LOCUS       DACGLI010000001       120811 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.001, whole genome shotgun sequence.
ACCESSION   DACGLI010000001 DACGLI010000000
VERSION     DACGLI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 120811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 120811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..120811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.001"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(37..1188)
                     /locus_tag="IXT22_000001"
     CDS             complement(37..1188)
                     /locus_tag="IXT22_000001"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAQ4861403.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1201..1638)
                     /locus_tag="IXT22_000002"
     CDS             complement(1201..1638)
                     /locus_tag="IXT22_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4861404.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1653..3419)
                     /locus_tag="IXT22_000003"
     CDS             complement(1653..3419)
                     /locus_tag="IXT22_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAQ4861405.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3683..4360
                     /locus_tag="IXT22_000004"
     CDS             3683..4360
                     /locus_tag="IXT22_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861406.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4363..5490
                     /locus_tag="IXT22_000005"
     CDS             4363..5490
                     /locus_tag="IXT22_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861407.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5690..6130)
                     /locus_tag="IXT22_000006"
     CDS             complement(5690..6130)
                     /locus_tag="IXT22_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4861408.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6141..8174)
                     /locus_tag="IXT22_000007"
     CDS             complement(6141..8174)
                     /locus_tag="IXT22_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4861409.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8176..9879)
                     /locus_tag="IXT22_000008"
     CDS             complement(8176..9879)
                     /locus_tag="IXT22_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4861410.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9973..10923)
                     /gene="manA"
                     /locus_tag="IXT22_000009"
     CDS             complement(9973..10923)
                     /gene="manA"
                     /locus_tag="IXT22_000009"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAQ4861411.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10962..11987)
                     /locus_tag="IXT22_000010"
     CDS             complement(10962..11987)
                     /locus_tag="IXT22_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4861412.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12196..13065)
                     /locus_tag="IXT22_000011"
     CDS             complement(12196..13065)
                     /locus_tag="IXT22_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAQ4861413.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13524..15416)
                     /locus_tag="IXT22_000012"
     CDS             complement(13524..15416)
                     /locus_tag="IXT22_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861414.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15413..17140)
                     /locus_tag="IXT22_000013"
     CDS             complement(15413..17140)
                     /locus_tag="IXT22_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861415.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17156..17806)
                     /locus_tag="IXT22_000014"
     CDS             complement(17156..17806)
                     /locus_tag="IXT22_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4861416.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18010..18306
                     /locus_tag="IXT22_000015"
     CDS             18010..18306
                     /locus_tag="IXT22_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4861417.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18478..19098
                     /locus_tag="IXT22_000016"
     CDS             18478..19098
                     /locus_tag="IXT22_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAQ4861418.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19190..20356)
                     /locus_tag="IXT22_000017"
     CDS             complement(19190..20356)
                     /locus_tag="IXT22_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4861419.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20368..20721)
                     /locus_tag="IXT22_000018"
     CDS             complement(20368..20721)
                     /locus_tag="IXT22_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4861420.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20849..21871
                     /locus_tag="IXT22_000019"
     CDS             20849..21871
                     /locus_tag="IXT22_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAQ4861421.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(22310..22744)
                     /locus_tag="IXT22_000020"
     CDS             complement(22310..22744)
                     /locus_tag="IXT22_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861422.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22854..24713)
                     /locus_tag="IXT22_000021"
     CDS             complement(22854..24713)
                     /locus_tag="IXT22_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4861423.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24831..25991)
                     /locus_tag="IXT22_000022"
     CDS             complement(24831..25991)
                     /locus_tag="IXT22_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAQ4861424.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26298..27722)
                     /gene="araA"
                     /locus_tag="IXT22_000023"
     CDS             complement(26298..27722)
                     /gene="araA"
                     /locus_tag="IXT22_000023"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAQ4861425.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27738..28436)
                     /locus_tag="IXT22_000024"
     CDS             complement(27738..28436)
                     /locus_tag="IXT22_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4861426.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28393..30054)
                     /locus_tag="IXT22_000025"
     CDS             complement(28393..30054)
                     /locus_tag="IXT22_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAQ4861427.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30272..31672
                     /locus_tag="IXT22_000026"
     CDS             30272..31672
                     /locus_tag="IXT22_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAQ4861428.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31924..33003)
                     /locus_tag="IXT22_000027"
     CDS             complement(31924..33003)
                     /locus_tag="IXT22_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4861429.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33089..34048)
                     /locus_tag="IXT22_000028"
     CDS             complement(33089..34048)
                     /locus_tag="IXT22_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAQ4861430.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34060..35583)
                     /locus_tag="IXT22_000029"
     CDS             complement(34060..35583)
                     /locus_tag="IXT22_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4861431.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35593..36156)
                     /locus_tag="IXT22_000030"
     CDS             complement(35593..36156)
                     /locus_tag="IXT22_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4861432.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36162..37025)
                     /locus_tag="IXT22_000031"
     CDS             complement(36162..37025)
                     /locus_tag="IXT22_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4861433.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37039..37935)
                     /locus_tag="IXT22_000032"
     CDS             complement(37039..37935)
                     /locus_tag="IXT22_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4861434.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38110..39381)
                     /locus_tag="IXT22_000033"
     CDS             complement(38110..39381)
                     /locus_tag="IXT22_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861435.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39371..40888)
                     /locus_tag="IXT22_000034"
     CDS             complement(39371..40888)
                     /locus_tag="IXT22_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4861436.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41086..41976
                     /locus_tag="IXT22_000035"
     CDS             41086..41976
                     /locus_tag="IXT22_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAQ4861437.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42049..42873)
                     /gene="nadE"
                     /locus_tag="IXT22_000036"
     CDS             complement(42049..42873)
                     /gene="nadE"
                     /locus_tag="IXT22_000036"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAQ4861438.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42885..44357)
                     /locus_tag="IXT22_000037"
     CDS             complement(42885..44357)
                     /locus_tag="IXT22_000037"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAQ4861439.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44994..45356)
                     /locus_tag="IXT22_000038"
     CDS             complement(44994..45356)
                     /locus_tag="IXT22_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4861440.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45579..46331
                     /locus_tag="IXT22_000039"
     CDS             45579..46331
                     /locus_tag="IXT22_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4861441.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46471..47394)
                     /locus_tag="IXT22_000040"
     CDS             complement(46471..47394)
                     /locus_tag="IXT22_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4861442.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47409..47681)
                     /locus_tag="IXT22_000041"
     CDS             complement(47409..47681)
                     /locus_tag="IXT22_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861443.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(48151..49776)
                     /gene="groL"
                     /locus_tag="IXT22_000042"
     CDS             complement(48151..49776)
                     /gene="groL"
                     /locus_tag="IXT22_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAQ4861444.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(49827..50111)
                     /locus_tag="IXT22_000043"
     CDS             complement(49827..50111)
                     /locus_tag="IXT22_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAQ4861445.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            50336..50998
                     /locus_tag="IXT22_000044"
     CDS             50336..50998
                     /locus_tag="IXT22_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4861446.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(51074..52366)
                     /locus_tag="IXT22_000045"
     CDS             complement(51074..52366)
                     /locus_tag="IXT22_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4861447.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            52536..53165
                     /locus_tag="IXT22_000046"
     CDS             52536..53165
                     /locus_tag="IXT22_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAQ4861448.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(53268..54077)
                     /locus_tag="IXT22_000047"
     CDS             complement(53268..54077)
                     /locus_tag="IXT22_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4861449.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(54132..55001)
                     /locus_tag="IXT22_000048"
     CDS             complement(54132..55001)
                     /locus_tag="IXT22_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861450.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(55002..56318)
                     /locus_tag="IXT22_000049"
     CDS             complement(55002..56318)
                     /locus_tag="IXT22_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861451.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(56315..58150)
                     /gene="walK"
                     /locus_tag="IXT22_000050"
     CDS             complement(56315..58150)
                     /gene="walK"
                     /locus_tag="IXT22_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAQ4861452.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(58155..58859)
                     /locus_tag="IXT22_000051"
     CDS             complement(58155..58859)
                     /locus_tag="IXT22_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4861453.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(59049..59909)
                     /locus_tag="IXT22_000052"
     CDS             complement(59049..59909)
                     /locus_tag="IXT22_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4861454.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(59896..60465)
                     /locus_tag="IXT22_000053"
     CDS             complement(59896..60465)
                     /locus_tag="IXT22_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAQ4861455.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            60846..60918
                     /locus_tag="IXT22_000054"
     tRNA            60846..60918
                     /locus_tag="IXT22_000054"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60879..60881,aa:Lys,seq:ctt)
     gene            complement(61414..61800)
                     /locus_tag="IXT22_000055"
     CDS             complement(61414..61800)
                     /locus_tag="IXT22_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4861456.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(61797..62318)
                     /locus_tag="IXT22_000056"
     CDS             complement(61797..62318)
                     /locus_tag="IXT22_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4861457.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(62320..63354)
                     /gene="sppA"
                     /locus_tag="IXT22_000057"
     CDS             complement(62320..63354)
                     /gene="sppA"
                     /locus_tag="IXT22_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4861458.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(63387..64802)
                     /locus_tag="IXT22_000058"
     CDS             complement(63387..64802)
                     /locus_tag="IXT22_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAQ4861459.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(64771..66924)
                     /locus_tag="IXT22_000059"
     CDS             complement(64771..66924)
                     /locus_tag="IXT22_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAQ4861460.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            67182..67418
                     /locus_tag="IXT22_000060"
     CDS             67182..67418
                     /locus_tag="IXT22_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4861461.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            67437..67652
                     /locus_tag="IXT22_000061"
     CDS             67437..67652
                     /locus_tag="IXT22_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4861462.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(68355..69107)
                     /locus_tag="IXT22_000062"
     CDS             complement(68355..69107)
                     /locus_tag="IXT22_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4861463.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(69122..70369)
                     /locus_tag="IXT22_000063"
     CDS             complement(69122..70369)
                     /locus_tag="IXT22_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4861464.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(70445..70591)
                     /locus_tag="IXT22_000064"
     CDS             complement(70445..70591)
                     /locus_tag="IXT22_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAQ4861465.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(70695..71006)
                     /locus_tag="IXT22_000065"
     CDS             complement(70695..71006)
                     /locus_tag="IXT22_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4861466.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(71008..71205)
                     /locus_tag="IXT22_000066"
     CDS             complement(71008..71205)
                     /locus_tag="IXT22_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAQ4861467.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(71599..73326)
                     /locus_tag="IXT22_000067"
     CDS             complement(71599..73326)
                     /locus_tag="IXT22_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4861468.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(73319..74512)
                     /locus_tag="IXT22_000068"
     CDS             complement(73319..74512)
                     /locus_tag="IXT22_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4861469.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(74699..75343)
                     /locus_tag="IXT22_000069"
     CDS             complement(74699..75343)
                     /locus_tag="IXT22_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4861470.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(75437..75571)
                     /locus_tag="IXT22_000070"
     CDS             complement(75437..75571)
                     /locus_tag="IXT22_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAQ4861471.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(75573..77705)
                     /gene="feoB"
                     /locus_tag="IXT22_000071"
     CDS             complement(75573..77705)
                     /gene="feoB"
                     /locus_tag="IXT22_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAQ4861472.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(77702..78175)
                     /locus_tag="IXT22_000072"
     CDS             complement(77702..78175)
                     /locus_tag="IXT22_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAQ4861473.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            78576..78800
                     /gene="nrdH"
                     /locus_tag="IXT22_000073"
     CDS             78576..78800
                     /gene="nrdH"
                     /locus_tag="IXT22_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAQ4861474.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            78959..81118
                     /gene="nrdE"
                     /locus_tag="IXT22_000074"
     CDS             78959..81118
                     /gene="nrdE"
                     /locus_tag="IXT22_000074"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAQ4861475.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            81168..82133
                     /gene="nrdF"
                     /locus_tag="IXT22_000075"
     CDS             81168..82133
                     /gene="nrdF"
                     /locus_tag="IXT22_000075"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAQ4861476.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(82222..83361)
                     /locus_tag="IXT22_000076"
     CDS             complement(82222..83361)
                     /locus_tag="IXT22_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4861477.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(83670..84383)
                     /locus_tag="IXT22_000077"
     CDS             complement(83670..84383)
                     /locus_tag="IXT22_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAQ4861478.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(84637..85338)
                     /gene="nagB"
                     /locus_tag="IXT22_000078"
     CDS             complement(84637..85338)
                     /gene="nagB"
                     /locus_tag="IXT22_000078"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAQ4861479.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            85572..87104
                     /locus_tag="IXT22_000079"
     CDS             85572..87104
                     /locus_tag="IXT22_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4861480.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(87295..88497)
                     /locus_tag="IXT22_000080"
     CDS             complement(87295..88497)
                     /locus_tag="IXT22_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4861481.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(88579..89268)
                     /locus_tag="IXT22_000081"
     CDS             complement(88579..89268)
                     /locus_tag="IXT22_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4861482.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(89374..89742)
                     /gene="rplL"
                     /locus_tag="IXT22_000082"
     CDS             complement(89374..89742)
                     /gene="rplL"
                     /locus_tag="IXT22_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAQ4861483.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(89795..90298)
                     /locus_tag="IXT22_000083"
     CDS             complement(89795..90298)
                     /locus_tag="IXT22_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAQ4861484.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(90708..91397)
                     /gene="rplA"
                     /locus_tag="IXT22_000084"
     CDS             complement(90708..91397)
                     /gene="rplA"
                     /locus_tag="IXT22_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAQ4861485.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(91501..91923)
                     /gene="rplK"
                     /locus_tag="IXT22_000085"
     CDS             complement(91501..91923)
                     /gene="rplK"
                     /locus_tag="IXT22_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAQ4861486.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            92266..92934
                     /gene="sdaAB"
                     /locus_tag="IXT22_000086"
     CDS             92266..92934
                     /gene="sdaAB"
                     /locus_tag="IXT22_000086"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAQ4861487.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            92947..93819
                     /gene="sdaAA"
                     /locus_tag="IXT22_000087"
     CDS             92947..93819
                     /gene="sdaAA"
                     /locus_tag="IXT22_000087"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAQ4861488.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(93910..94929)
                     /locus_tag="IXT22_000088"
     CDS             complement(93910..94929)
                     /locus_tag="IXT22_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4861489.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(95102..95989)
                     /locus_tag="IXT22_000089"
     CDS             complement(95102..95989)
                     /locus_tag="IXT22_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4861490.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(96066..96611)
                     /gene="nusG"
                     /locus_tag="IXT22_000090"
     CDS             complement(96066..96611)
                     /gene="nusG"
                     /locus_tag="IXT22_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAQ4861491.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(96712..96882)
                     /gene="secE"
                     /locus_tag="IXT22_000091"
     CDS             complement(96712..96882)
                     /gene="secE"
                     /locus_tag="IXT22_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAQ4861492.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(96906..97058)
                     /gene="rpmG"
                     /locus_tag="IXT22_000092"
     CDS             complement(96906..97058)
                     /gene="rpmG"
                     /locus_tag="IXT22_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4861493.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            97220..97864
                     /locus_tag="IXT22_000093"
     CDS             97220..97864
                     /locus_tag="IXT22_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4861494.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(97920..98423)
                     /locus_tag="IXT22_000094"
     CDS             complement(97920..98423)
                     /locus_tag="IXT22_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4861495.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(98436..98482)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            99020..99985
                     /locus_tag="IXT22_000095"
     CDS             99020..99985
                     /locus_tag="IXT22_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4861496.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(100084..101256)
                     /locus_tag="IXT22_000096"
     CDS             complement(100084..101256)
                     /locus_tag="IXT22_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861497.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(101243..102388)
                     /locus_tag="IXT22_000097"
     CDS             complement(101243..102388)
                     /locus_tag="IXT22_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861498.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(102402..103326)
                     /locus_tag="IXT22_000098"
                     /pseudo
     CDS             complement(102402..103326)
                     /locus_tag="IXT22_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            103443..104522
                     /locus_tag="IXT22_000099"
     CDS             103443..104522
                     /locus_tag="IXT22_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4861499.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            104554..105147
                     /locus_tag="IXT22_000100"
     CDS             104554..105147
                     /locus_tag="IXT22_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4861500.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(105257..105484)
                     /locus_tag="IXT22_000101"
     CDS             complement(105257..105484)
                     /locus_tag="IXT22_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4861501.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(105587..108175)
                     /locus_tag="IXT22_000102"
     CDS             complement(105587..108175)
                     /locus_tag="IXT22_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAQ4861502.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(108195..108854)
                     /locus_tag="IXT22_000103"
     CDS             complement(108195..108854)
                     /locus_tag="IXT22_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4861503.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(108903..109406)
                     /gene="trmL"
                     /locus_tag="IXT22_000104"
     CDS             complement(108903..109406)
                     /gene="trmL"
                     /locus_tag="IXT22_000104"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAQ4861504.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(109627..110493)
                     /locus_tag="IXT22_000105"
     CDS             complement(109627..110493)
                     /locus_tag="IXT22_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4861505.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            110602..111243
                     /locus_tag="IXT22_000106"
     CDS             110602..111243
                     /locus_tag="IXT22_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAQ4861506.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(111305..112666)
                     /gene="mgtE"
                     /locus_tag="IXT22_000107"
     CDS             complement(111305..112666)
                     /gene="mgtE"
                     /locus_tag="IXT22_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAQ4861507.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(112684..113583)
                     /locus_tag="IXT22_000108"
     CDS             complement(112684..113583)
                     /locus_tag="IXT22_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4861508.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(113585..114382)
                     /locus_tag="IXT22_000109"
     CDS             complement(113585..114382)
                     /locus_tag="IXT22_000109"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAQ4861509.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(114360..115064)
                     /locus_tag="IXT22_000110"
     CDS             complement(114360..115064)
                     /locus_tag="IXT22_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAQ4861510.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            115195..115770
                     /locus_tag="IXT22_000111"
     CDS             115195..115770
                     /locus_tag="IXT22_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAQ4861511.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            115888..116565
                     /locus_tag="IXT22_000112"
     CDS             115888..116565
                     /locus_tag="IXT22_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4861512.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(116644..118452)
                     /gene="pepF"
                     /locus_tag="IXT22_000113"
     CDS             complement(116644..118452)
                     /gene="pepF"
                     /locus_tag="IXT22_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAQ4861513.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(118628..119626)
                     /locus_tag="IXT22_000114"
     CDS             complement(118628..119626)
                     /locus_tag="IXT22_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAQ4861514.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(119852..120505)
                     /locus_tag="IXT22_000115"
     CDS             complement(119852..120505)
                     /locus_tag="IXT22_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAQ4861515.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        35803 a        24986 c        20657 g        39365 t
ORIGIN      
        1 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
       61 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
      121 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
      181 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
      241 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
      301 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
      361 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
      421 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
      481 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
      541 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
      601 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
      661 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
      721 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
      781 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
      841 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
      901 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
      961 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
     1021 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
     1081 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
     1141 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
     1201 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
     1261 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
     1321 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
     1381 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
     1441 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
     1501 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
     1561 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
     1621 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
     1681 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
     1741 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
     1801 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
     1861 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
     1921 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
     1981 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
     2041 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
     2101 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
     2161 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
     2221 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
     2281 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
     2341 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
     2401 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
     2461 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
     2521 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
     2581 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
     2641 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
     2701 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
     2761 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
     2821 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
     2881 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
     2941 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
     3001 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
     3061 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
     3121 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
     3181 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
     3241 cttaccatgg tagccaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
     3301 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
     3361 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
     3421 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
     3481 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
     3541 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
     3601 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
     3661 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
     3721 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
     3781 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
     3841 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
     3901 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
     3961 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
     4021 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
     4081 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
     4141 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
     4201 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
     4261 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
     4321 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
     4381 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
     4441 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
     4501 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
     4561 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
     4621 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
     4681 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
     4741 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
     4801 ccagcgcatc tccctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
     4861 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
     4921 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
     4981 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
     5041 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
     5101 attggtcagg agatacgaat ccttccgatg tatgagtatc ttttccagag ctttctgttc
     5161 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
     5221 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
     5281 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
     5341 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
     5401 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
     5461 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
     5521 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
     5581 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
     5641 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
     5701 catgttcaaa aatcatttgg acttcttcaa tggttttcgc atcactgagc gccattactt
     5761 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
     5821 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
     5881 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
     5941 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
     6001 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
     6061 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
     6121 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
     6181 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
     6241 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
     6301 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
     6361 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
     6421 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
     6481 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
     6541 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa acgaccgagt
     6601 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
     6661 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
     6721 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
     6781 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
     6841 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
     6901 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
     6961 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
     7021 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
     7081 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
     7141 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
     7201 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
     7261 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
     7321 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
     7381 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
     7441 agactattat atgtctcatt tgtcagtaaa tgatttttag tcacacgctc catcgtcaat
     7501 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
     7561 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
     7621 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
     7681 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
     7741 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
     7801 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
     7861 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
     7921 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
     7981 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
     8041 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
     8101 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
     8161 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
     8221 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
     8281 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
     8341 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
     8401 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacttttt
     8461 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
     8521 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
     8581 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
     8641 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
     8701 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
     8761 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
     8821 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
     8881 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
     8941 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
     9001 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
     9061 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
     9121 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
     9181 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
     9241 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
     9301 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
     9361 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
     9421 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
     9481 agccttgaat ttcacgtgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
     9541 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
     9601 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
     9661 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
     9721 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
     9781 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
     9841 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca tacttctatt
     9901 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
     9961 gctatctggg aactatttgc ctggttcagt cgcaatgatt gctagttcac cttggaccgc
    10021 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    10081 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    10141 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    10201 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    10261 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    10321 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    10381 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    10441 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    10501 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    10561 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    10621 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    10681 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    10741 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    10801 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    10861 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    10921 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    10981 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    11041 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    11101 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    11161 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    11221 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    11281 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    11341 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    11401 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    11461 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    11521 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    11581 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    11641 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    11701 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    11761 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    11821 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    11881 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    11941 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    12001 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    12061 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    12121 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    12181 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    12241 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    12301 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    12361 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    12421 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    12481 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    12541 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    12601 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    12661 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    12721 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    12781 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    12841 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    12901 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    12961 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    13021 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    13081 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    13141 gttaaaaaaa atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    13201 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    13261 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    13321 gaacaccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagataca
    13381 aaacggaaaa atagcttctc atattttgcc gttttttgag ctaataccga aggacagctg
    13441 attgaacacc gtttattcgg aaaaagggac tgtgacacga cttttgtcac agcccctaaa
    13501 aaaaataata aatttgtact attctatgaa gcttcttctt cagaaaactg actgttataa
    13561 agatctgcat agaatccgtc tttttccatc aatgtatcgt ggtttcctgt ttctacgatc
    13621 gaaccatgat tcatcacaat aatgttgtct gcatcgcgta ttgtagacaa gcggtgagca
    13681 acaacgaaac ttgtccggtt ttccaatagg cggttcatcg ctttttgaat cagtatttct
    13741 gttcgtgtat ctacactaga tgttgcttca tcaaggatca ggacatctgg atttgctaag
    13801 aatgcccgcg caattgtgat tagctgacgc tgcccttgcg aaatattgct tgcatcctcg
    13861 tttaatacag tgttatatcc ttctggcaat ttacgaacaa aatcgtctac gtgagcagct
    13921 ttagcagcct caatgatttg ttcgtctgtt gcatcgtcgt tcccatattt gatattgtca
    13981 tagatacttc ctgtaaacag ccaagtatct tgcagtacca ttgaaaactg tgcgcgcaat
    14041 tcatcacgtg aaagatcacg ggtatctaca ccatcgtaac gaatactacc tccagaaaca
    14101 tcgtagaacc gttcaagaag gttgatcagt gtcgtcttcc ctgcaccagt cggacctaca
    14161 atagcgacca tctcaccagg tttgacatcc aagttaaaat cagtcattag caagttatct
    14221 ggtgtgtagc cgaattgaac attttcaaaa cgaactttgt atggtgtatc tttttcttct
    14281 ggaaggccag atttttcatt ggacatctct tcttcatcca acacttcaaa tacccgttcg
    14341 gctgaagcaa ctgttgattg gatagtgttc atcaaacttg caagttgagt gattggttga
    14401 gagaactgtg ttgtatattg caagaacgct tgaacatccc ctaatgtcat gttcccattt
    14461 gcaactttta ctccgcctag tacagcgacg aacacatagc ctagattttt aacgaaattc
    14521 atcaacggca tgatgattgc cgaaataaat tgagctttcc aaccagcggc atacagattc
    14581 tgattttctt tttcaaatac ttcctggtct ttttcagtat gattgaatgt tttaacaatg
    14641 gtatgaccac catatgtttc ttctacttgg ttattcaata aacctaaact tttttgctga
    14701 tctgcgaaaa acacttgtga tttcggcgct acgatcatca cgatgatcaa gcttaaaggg
    14761 atcatcaata acgcgactaa cgtcaattgc cagctgattg aaagcatcat cacgatgacc
    14821 ccaatcaatg tgactgcact agttacaaat tgagtcaaat tttgctgcag cgtgcttgcg
    14881 atgttatcca tatcattgat tgctcgagac atgatatccc catttgtatg tgtatcataa
    14941 taggaaatcg gtacacgatt cattttggct tccaaatcat gacgtaattc ataaactgtt
    15001 cgttgggaaa cacgtgtcat aataaattgc tgtaaaaagt tgaatacagc agaaatcaaa
    15061 tacatcacga ttactgtcgc aatgatctgc gcgattttat caaagtctat cggaaatttt
    15121 gttacttgtt ggccttgttg catctgttga gcgccagcca ttacaccttt gaatatttct
    15181 gtggttgctt tccccaagac ctttggtgtt tggatttgga agatcacggc tgctattgct
    15241 agtacaaata cagcgatgat cgcaaccata cgtttagaca tatagccaaa caatcggcgt
    15301 accgttcccc agaaattttt aggcttttca ccttttacac cgagatttct gccaggtcca
    15361 ccatgtcctg gaccgcctgc tggtccatga gagggacgtg tgtttgtttt actcatgcta
    15421 agtcctcctc tcttagttgt gaatgaacga tttcttgata agtttcgttt gttgctaata
    15481 gttcttcatg tgttcctttg ccaaccagtt ttccttcatc tagcacaagg atcatatctg
    15541 catccattac tgtacttact cgttgagcaa ctaaaacggt gatactttct ttcatattcg
    15601 ttttcaatgc ttggcgaaga ttggcatccg ttttgaaatc caacgctgag aaggaatcat
    15661 caaacacata gatatctgct gttttgacta atgcccgtgc aattgccaga cgctgtcttt
    15721 gtccaccaga gaagtttcct cctccttgtt ccacatggct atctaagcca tcttccatct
    15781 ctgaaacaaa atctttagct tgtgcgattt ctaatgcttt ccaaatcatt tcatctgttg
    15841 catccggctt accatactgc atattgtctc ggatcgttcc agagaacaga actgcttttt
    15901 gaggaacaaa gcccattaat tctcgcaaat tatattgagt catgtcacta atgtccgttc
    15961 catttatttg gatcgaacca gattcgatgt catataatcg agggatcaaa ttgactaagg
    16021 tcgttttacc tgaaccagtc ccccctatga ttgcgacgat ctcgcccgac ttggcttgga
    16081 aatcaatatc ttccaatgca agtttttctg ctccatgata tcgataattg acatgattga
    16141 aggccaatgt tgcgtttttt ccagcaaaag aaactgtttt aggattttca gggtcatgga
    16201 taccgatttt ttcatccaac acttcattaa tacggtcagc tgaagcttgt gcacgaggca
    16261 ccatgataaa aatagcggaa agcatcataa agctgatcaa gatctgcatc gcataagtca
    16321 taaatgcaat cagattaccg acttccaaag tcatatctgc tatgtagtgt ccaccaaacc
    16381 aagtgattgc tacgtttgta ccgctcatga tcaatgtcat cattggcatc atcaatgcga
    16441 cgatcgtatt aactttgatt gccgtatttg tataatcttt attcgctaaa tcaaaacgat
    16501 tttcttcaaa gcgtgtctta tcgaatgctc gaatcactct gacccctgtc aatccttctc
    16561 gaaataccag gtttaaacgg tcagttttct tttgcatact tttgaataat ggaacagcaa
    16621 agtacatgat tccgccgatc aaaataatca ttactgggat gacaactaag aagatttttg
    16681 tcaactgatg atctttttga taagcaagta tgctcgcgcc aatcaacgtg attggtgcat
    16741 tgatcatcat acgtaaaaac atttgtgtaa ccatttggat ttgagtcaca tcattggtcg
    16801 ttcttgtgat caaagaggcc gttccatatt tatcaaacgc atcttttgtc agactctctg
    16861 attttttata gacatccgta cgcaattgct tacccagttt ctgtgattca cgagtagcaa
    16921 aaaatgtatt tgcgatagca gctaagatac tgatcaaaga aaagccgatc atcacaaaac
    16981 ctgtatgcca aatataatcg acatctcctt gcgctacccc tttatcaata atattggagg
    17041 taagtgtcgg caaatataaa tctgccagta cttggatcac catgaaaact gcagctgcaa
    17101 ttgctgaagt caaggagatc cgttttacga tttttagcat ctagttccct tctttctatt
    17161 tatatactcc gtttttcagc caagaaagtt tcaaattgaa ttcactgatt gcttgctcta
    17221 ctgagtaatc ttcagatgtt gaaaataagc gatacgaatg cgcaattgtt gtaaatacag
    17281 tattcatcac taattggatc agtaattcca attcatgatc attttttact ttcagcttcg
    17341 tccgatcgat caattcaagc aactcttttg catcttgttt gtgttcttta tgtggatcgt
    17401 gaggcgtttt ttggcgactc gtatgaggag cgacttttct tgaggcacgg taatccatgt
    17461 tcataaacaa gttacgataa aaagaagcat tctcgccttc caaaatctca taaatcattt
    17521 tagaaaaata ggattcgaat cctttgaata gatcaccatc ggattctttc attagttgta
    17581 acatatcttt agagctgtca cgtctcattg tctcaaagta ataaaaataa agatcctctt
    17641 tatcttcaaa atactgatag aaactgcctc tagggatatc cgctaatttg acgatattag
    17701 caatcgaagc ttcttttaag ggtactctag aaaactcgat tctcgcagcc tcgattagtc
    17761 ttttttgttt ttctttaggc aaatggaaaa atgtctgtgt cggcatatgg atcctccttt
    17821 ctttcaagat gacacattgt catatgacgc tgtgtcatta taacacctcc tacctgtttt
    17881 gcaagacatt tgcatagttt ttttcattat catccgatac attaaaaaag tgataagagg
    17941 aatccttcca tttgaattaa tgagagttgc ccattaaaat agccacatac taaacaaagg
    18001 atgagataaa tggcccaatc aattagtgtc caagacttca ataaattgcc tctcgatgct
    18061 gacagcatcg ttttagatac aagaaatacc ttagattaca caaaaaacca cttaagccac
    18121 tcgctttcta tccccgctgc tatcttgcca agacaattaa aaaatctaga tccaaagaaa
    18181 ctttattata ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact
    18241 gctaatggtt ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt
    18301 gcttgaatat tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc
    18361 ttttataccc tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag
    18421 ccttttcttt ttctcatagt tataacaatc atagcaataa aaggagaagg taagcatatg
    18481 gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg cacagttaag
    18541 gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga agtgactgtt
    18601 ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc aggttgggaa
    18661 gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca aaaaattgct
    18721 cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat cgcaaacgcc
    18781 ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt caatgtagct
    18841 ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg taaaaaagca
    18901 ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc tcaatatgta
    18961 aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat cgaaggaatc
    19021 gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa agctgctgct
    19081 ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga ggaaaaaatc
    19141 ttcaaagcag catttgtacc ttggatattt tcccatctgt ctctttttgt tattctttct
    19201 gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat tcaaaaacat
    19261 gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca ccgatgattc
    19321 cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg attgctaact
    19381 gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct actgcaaaaa
    19441 cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag atagccggaa
    19501 tcatcgctaa aaatgatcct aagtaaggga tcaggttcaa aaaacccgca ataatcccca
    19561 acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg attgccacag
    19621 caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc atttcactca
    19681 gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa taaggtgcta
    19741 attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc agagccacta
    19801 aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc ttagatatat
    19861 cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc aactgttcgc
    19921 gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca atcgtatcta
    19981 catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta gggatgatca
    20041 ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg atactgtaaa
    20101 gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag taatacaaga
    20161 ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt ggtgcaaaca
    20221 aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca acaagtaagg
    20281 ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt ctgttcttct
    20341 tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc ccaaaccaat
    20401 agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt cttctggaca
    20461 agcatcaaaa atcaatgata cgtgagctac tgtctctaaa ttcccattgg ccatcggacc
    20521 gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg ctttcaaaga
    20581 aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg cagctgttgc
    20641 tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg tcccaatttc
    20701 tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa acagtataac
    20761 acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac gaaaactatt
    20821 tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag gaacctatac
    20881 gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag aagaattagc
    20941 caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa gtaaagctgg
    21001 caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt acgataagga
    21061 ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg tagcggttga
    21121 tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa atgtctacca
    21181 tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag aagcgacagg
    21241 tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc ctgaccaacg
    21301 attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt ccgaaaacgg
    21361 caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc gccatcttgt
    21421 ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca cagtccgcgt
    21481 gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat cgaccttgcc
    21541 agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg atggcaagtt
    21601 cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt ttgaagatgg
    21661 ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc gcgatttcgc
    21721 actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata atctgacatt
    21781 atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg tctatgtacc
    21841 agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa tgaatcagca
    21901 agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg ggaaaatcga
    21961 agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac agaactactt
    22021 tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct gaaaagaaca
    22081 tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa aaccgccgag
    22141 atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac aaggttgttg
    22201 ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata aaggtaatat
    22261 tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt tattttttca
    22321 acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct tggtcttgtt
    22381 ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg atactttgga
    22441 tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt ttatgaatgc
    22501 ccattgcttt tgctggtgga cgcaaagtac tgactttctt aagcattgcc cgatattttt
    22561 ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc agttcacttg
    22621 tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt ccttctccga
    22681 ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca atattcggta
    22741 acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt gtttttatcc
    22801 tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca ttcttattcg
    22861 tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc atattggatc
    22921 aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc tttataccac
    22981 tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc taatgataaa
    23041 agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt cgctgcaaaa
    23101 taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc tttactgtcg
    23161 aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg gatcgtatct
    23221 gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct agaaagattc
    23281 ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc ttgcagataa
    23341 ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc tagattatca
    23401 tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa ctgaggtgtt
    23461 ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga aatatatgga
    23521 ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg gtcaaatcct
    23581 aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg gatcgctgtc
    23641 gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc catttttggt
    23701 acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga aaaaccagtc
    23761 aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag catattgcca
    23821 ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga tacttctacg
    23881 ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat gttcggcgac
    23941 tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc agtgatttct
    24001 ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt cagattgtac
    24061 aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta aggtatccat
    24121 agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa attactgata
    24181 taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg gaatcgcctt
    24241 ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt tcctgcggca
    24301 gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc gatttcagtg
    24361 atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt catataattt
    24421 gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg gacagatcct
    24481 gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa gaagaatttt
    24541 tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc attttgacac
    24601 cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat tgctgctgtt
    24661 ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt caaatgcttg
    24721 ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt acgaaattcg
    24781 aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct ttatggcctt
    24841 tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag ctgttgtttc
    24901 acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta gacatgctca
    24961 ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag cagagaaaat
    25021 atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa cggcgcttgg
    25081 aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa caaaagataa
    25141 tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg agtcgatccc
    25201 cctagatgag gcaacataag tatacggtca ttttctaaga actcttcttc tggaaaatca
    25261 gtcaagtatt tagccagatg ttgtttttcc aatgcttgca taacagcata tttatcaaca
    25321 atttcacttc ttcctacatt gataagtaca gcatcttttt tcattttttc tatattcgcc
    25381 tgatcgatca atccttttgt atcttctgtc aacggcagca tgactacgat gtaatccgag
    25441 gtagaaagaa ctgtttctaa atctgcttgc cgaacataat ccaactgggc atcgcggata
    25501 gaataaccca agacatccat ccctaagcta tagcaactta gcgctacttt tgtgcctatc
    25561 gctccaagac caagaagacc gatggttttg ccttgcaatt ctcgtcccac ataagcactt
    25621 cttttgtttt ctgcctgttc taaaatatta ggacctgtta gtgtttgtac catacgactt
    25681 gcttcgatta tcggacggga agataagagc aaacagcaca aaacaagctc ttttactgca
    25741 ttagcattta cacctggtgt attcatgacg atcgtcccgt tttcagaagc tttttcaacg
    25801 ttgatcgtgt tcaccccaac accagctctt gaaattgcta gcaaatctgg tgtaagccat
    25861 tcatctttca ctttcgtact acgaataact attccttcgg ctggcaaatc atctattatt
    25921 ttgaaatatt ccccttgtaa cttttctatc tcttgttctg gaatagcatc aatcaaatga
    25981 acgtgataca taaaaccccc tccttactaa caagtatctc gaaatttctg caattagaca
    26041 actgtttacc atttgacttc ctagaagcaa aaagagcagt tagagcagag taggctgagt
    26101 gataaaaata aggctatgac aagttactgc cataagcctt attttcgaga gcaaaatatt
    26161 gagggtgaga tatcttgata aatggtgttc cgttagctga cattgataat aagactaaat
    26221 ttcaaaaaag ttgaaaagca aatttcgtca atctcttctt atttcttaaa actaagtggc
    26281 tttttcacaa cctcttttta tctaataacc actgtttcca actcaactaa ttttgcccac
    26341 gtttcaattt gatctgttgt tagatttagc gagacaacgg tatgatgacc gccacctgcc
    26401 tgaatccatg aatggacacc ttcatggaaa ttcggtttag ttttccataa cacacgtgca
    26461 acaggtaaat taggtgcttc agtcgttggt tcaaaggctt ctacttcatt gatcagcagt
    26521 ttataatgcg taccgaaatc tgccatcgat acgactaccc cttctcctgc tttcccatca
    26581 aatacaagac gcgccggatc ttctctatct cccattgata aaggagaaac aacgattctt
    26641 ggtttcgtcg cagcaagcgt cggatctact tccatcatat gggattccaa gattgcttct
    26701 tggccactag ctagctcgta agtataatct tccatgaatc ctgtatcttt ccctcgagcc
    26761 atgattttca gcaaccgatc aatcgctgca gttttccagt cgccttcccc agcaaaaccg
    26821 tatccttctg ccatcaaacg ttgtacagct agtccaggta gttgtttcat tccatacagg
    26881 tcttcaaaat tagtcgtaaa agcgttatag cctccttctt ctaagaaacg gcgaataccg
    26941 atttcctgct gagcttgtac ttttacatgt tcctcccatg tcttttcttc ataatcacca
    27001 tagtcgaagg tatacaattc cttgtactct tcaaataatt gatcgacttc ttcgtctgat
    27061 acgcgatcga ttacttgtac aagatctccg ataccaaaat aatcaacagt ccaaccaaat
    27121 tgaatctgtg cttccacttt gtctccttct gtgacaccca cgtttctcat gttgtcacca
    27181 aaacgagcca cttttattcc aaaactttca ttataggcta ctgcaacatc catccaatca
    27241 gcaatctctt tttggatctc aggtcgtttc cagtagccaa cgacgatttt attttgttta
    27301 tttaatcgag cattgatgaa cccatattcg cggtcaccat gagcggattg atttaaattc
    27361 atgaaatcca tatcgatcgt tttccaagga atgctttcgt tatattgcgt agctaaatga
    27421 agcaatggtt tttgtagaag ctttgtcccg cggatccaca tttttgctgg tgagaaagta
    27481 tgcatccaag tgatcacacc tgctacttct tctcgataat tgacctcttt catgattttt
    27541 gtgatcgtat cagcagtaac tgctaattct tgaaggcgga ttggataagg caattggcca
    27601 ttttcattca gttcatcgac catttcttgt gcatgtttct ttacttctcg cagtgcttct
    27661 tccccatata aatgctgtga tcctacaaca aaccaaaatt ctttttctcc aatattcaac
    27721 ataattagcc actcctttta tttgttttgt ccgtaatacg cattttttcc gtgttttcgt
    27781 aaataatgtt tatctaaaat ccgttgaggc agctcttctg aaaatgaatt gagctgtctg
    27841 gtaaataaat tcatcttgca tacttcatct agtacgactg cgttcattac cgcactttgc
    27901 gcatctttcc cccaagtaaa tggaccgtgt ccgtgtaaaa gtacccctgg aattgctaag
    27961 ggatcaattt tgcgttcttt gaatgtttct atgataactt ttcctgtttc atattcgtac
    28021 ccgctgtcga tttcctgttg tgtcaaaaat cgagcacaag gtaccgatcc ataaaaagta
    28081 tctgcatgcg tcgtccccat cgcaggaaca tccaatcctg cttgtgccca gatcgtcgcc
    28141 catgtcgagt gagtatggac gattcctccg atttgaggaa atgaacgata taaaacagca
    28201 tgagtaggcg tatccgaaga gggattgagt ttaccttcaa tgatatgatt gtccaagtcc
    28261 acaacgacca tgtcgtctgc tgtcatctct tcataactga ctccgctagg tttgataacg
    28321 aaatatcgtg tttcaggatc aaaagcgctc acatttcccc atgtatattt gacgagtccg
    28381 tgtttaggca agtcaagatt tgcttggtat acttcttctt tcagttgttc cagcattttc
    28441 tatcactcct ttttcttgca attgatgaat cgctgttttt tcaatgtcga tcccctcacg
    28501 gtaacgtctc ataaatatct gatagcctgc tatttcttct gctgaaggtg tgatggtgat
    28561 tccttggtct tgtccaaaca cgtcttctgc caagaagttt tctaaagact tcccatgtcg
    28621 atccatcata taggctgcta ataacgcgat tccccacgct ccaccttctc cggctgtgtc
    28681 catcactgta actggtgcct ccatagcaga tgctagaatc cgctgtccaa cttctggtgt
    28741 tttaaaaatc cccccatgcc ccactaaacg atcaatttgg acattctcag atttcaatat
    28801 atccattccg attctcattg caccaaaagc actggctaaa tggatccgca tgaaattcgc
    28861 taaatcaaaa cggctacctg gtgtacgtac aaataatggc cttccttcat ttactcctgt
    28921 aatgttttca ccggaaaaat aaccataaga aagtaatccc ccgcaatccg tatcgccttc
    28981 tagcgctttg ttgaataata ccgtgaataa tttatctctg cttatctcca tacccaaaga
    29041 attggtaaat tcttcaaaaa tactgaccca agcattgata tccgaagagc agttattcgt
    29101 atgaaccatg cctactagtt ctcctgaagg tgtagtgacc atgtcgattt ccggatggac
    29161 attttctagt tctttttcta atacgatcat agcgaaggcg gaagtaccag ccgaaatgtt
    29221 ccctgtccgt ttggctacac tgttcgtagc gaccataccg gttcctgcat ccccttctgg
    29281 cggacaaacc gggattcctg gtctcaaatt tcccgtaggg tcgatcagat aagcccctga
    29341 ttcgcttaac ttgccagctt cttctcctgc tactagaact ttaggcaaaa tgtgatccaa
    29401 gtcaatcgct acgtgcgctt tttcgattaa ctgaccaaaa atatttttca tttcttgatg
    29461 gtaggttttc gttgaaggat cgataggaaa catgcctgat gcatctccta cgcctagtac
    29521 tttctcacca gtaagctgcc aatggacata acctgcaagc gttgtcaaaa aattaatttc
    29581 tttcacatgt tcttctttat tcaaaataga ttgatacaaa tgagcgatac tccatctctg
    29641 cggaatattg tattgaaatt tttccgttaa tattcgttct gcttcttcag tgattgtatt
    29701 tcgccaagta cgaaatggta ctagtaactg ttccttgcta tcaaatgcta gataaccgtg
    29761 catcattgca ctgaacccaa tcgacccgat tgtcgtaaga ttctcgccat agatttcgaa
    29821 tacttctgct gccatttttc ggtaactgac gcgcagtcct ttccaaatat cttctaatga
    29881 ataggtccag ataccatttt ctagtttgtt ttcccactca taactaccag cggcaatagg
    29941 agtaaaagat gaatcaatca atacagcttt gatcctagtt gatccaaact caatccctaa
    30001 agatgtacga ccatctatga catctaacat actttgcgca tttacttcct tcataatgat
    30061 ttaactccct ccttctcgtc aaacctgatc aaaccgtctt tttagtagcg cttacaatga
    30121 ttattgtata cttttgtacg tacatgtcaa gcggttattt acaagaatac aataaaaaac
    30181 acttgttttg tacgtacata agttataaaa tgaaattgct tacaaaatct gatcaaccgc
    30241 cttctcgaaa ttctagaagg agagaatact tatgaaaaaa gaaaaaaaag tttcctcatc
    30301 gtttatttat ttttttggcg catttggcgg cattctattt ggatatgata ttggtgttat
    30361 gaccggcgcc ttaccttttt tacagcatga ttggggtttg gcaggtaaag cttctttgat
    30421 aggatggatc acgtcttcgg tcatgttagg tgcgatcctt ggcggctctt tatctggtct
    30481 tctttctgat aagcttggac gacgaaaaat gattcttctt tctgcactta tttttatggc
    30541 tggttctgtc ctttctgcat ctgcccctca caatggttct tattttctga ttgcagcaag
    30601 gattcttcta ggtttagctg ttggcgctgc atctgcccta gttcctgctt atatgtctga
    30661 aatggctcct gctagactaa ggggaagatt gtcagggatc aatcaagtga tgattgcttc
    30721 tggcatgctc ctttcctatg ttgcagatta tttgctaaaa gtgttgcctg aaacgatggc
    30781 ttggcgcgtg atgttagggc tcgctgctgt ccccgcgctg attttatttt tcggtgtttt
    30841 agctctacca gagtcaccgc gttttcttat gcaatctggc cgcttggaag aggcaaaaag
    30901 agtattgaac tatattcgga caccaaaaga agctgaacag gaattcgaac aaatccagct
    30961 gaatgtcaaa caagaaaaga caaccggaac ttcttggcat actttgtttt tagaaaaata
    31021 tcgttcctta gtcattgccg gtattggtgt agcagtattc cagcaatttc aaggagctaa
    31081 tgctattttt tactatattc cgctgatcgt agaaaaagcg actgggcatg cagcgagcga
    31141 tgcattgatg tggccgatca tccaaggaat cattttagtt gctggttctt tgctcttttt
    31201 ggttattgca gacaagttca atcggcgaac tttattgaaa ataggcggta gcgtgatggg
    31261 actttcattc atcctaccag ctgttttagg aactgtactg gatgctcata caaattcgtt
    31321 gttgattctc ttgtttttat gtatttatgt cgcattttat tcttgcacat gggctccact
    31381 gacatgggta atcataggcg aaatattccc actagctgtc cgcgggcgag catctggcct
    31441 agcctcttct tttaattgga ttggttcttt cctagttggc ttgctttttc ctgtgatgac
    31501 tgcttctatg tctcaagaaa tcgttttcgg catttttggg atcatctgct ttttaggggt
    31561 tttatttatt caagagatcg taccagaaac tcgtgggaaa tctttagagg aaatcgaaca
    31621 aagtgcatct aaaaaaactt atcctaaacg tatttctatc catcattctt aaagaggttg
    31681 tgacagaagt ggtcagcttc aagaaataag aaggaaccgc ttagtttcca gtcacaagga
    31741 acaatttcaa aaaacagctt ctcatgtttg atgaatattg tgacttgtga ccagttggta
    31801 ggagaacacc gtttagtgga gaggtggtga aagaaacgtt cagccttgag cgatgacaaa
    31861 agctctcaca aacattgcga cgagtaaccg taggagcaat aagaggcggt aaaaacccgt
    31921 ctcttatttt tcgttttctt tcactgtttc ccgttcaact agtacaggtt catagagaat
    31981 atttggctgt gcctgtcctt tttcaatcgt tgtgacgatc caccgtgcgg catcttgtcc
    32041 caacttttct tttggatgcg tcaatgttgt caatttttta ttccctaaat ggcttaaaga
    32101 agaatcgtct gttcctacga tcgataggtc atctggaata tgatagccat tttctgtcaa
    32161 cttatctagc attaaactag ctatttgatc gttatagcaa atgatgccat ctaaagcttg
    32221 ttcttctttc aaccgttgta ctgttttttc agcgattgtt tctcgtgttt ccgtggtgaa
    32281 agtaatgata tcttccgtca aaaaacgcac attatactgt tcacacgcgc tgataaaacc
    32341 tttcatcctg tattttcctt gaagatcgtc gatttttgtg atgaacaaca gacgctgatg
    32401 tccttttttt atcaaatatt ctgctgccat aaaaccgact ttcacatcat ctaaacaaat
    32461 ataagaggca tttaactctt cataagcagc attgatcatc accatcggaa tgccttgttc
    32521 tctcaaagca acataaagtg ctaagtttgg gttatactga ttacttttcg taggctcaac
    32581 gatcaaacca tctaccccat aagcaatcat tttcttcaaa cactctttct ccaattcgtg
    32641 atcgttattc gtactggcta aaagcaatga atacccagat tctcgtaatt cattttcgat
    32701 tcctcggata atcgacggaa aaatataatc agagagatat gtggtgatga caccgatcgt
    32761 ttttgttctg ttcaatggtg ttttttcttt cttatagctg tcatctacat atgtgcccga
    32821 ccctttttct ttacgcagat agccctcatt taccaacaca gcgattgctt gccgaatcgt
    32881 atgtctgctg acgtcatata tttcttgcag cttgaattct gagggaatgg ttgtatttac
    32941 ttcgtattcc tcacgaagga tcttttgttt tatctcttct gcaatatctt gatattttgc
    33001 catttgcctt gccccttttt atttgtacgt acatatatca taacgagtct gcaaggttta
    33061 ttcaagcaaa aatcaaggtt tcttgtgctc ataaggcata cggaacaggt tcaccaaatt
    33121 ctggaaatcc ttgctcattc cacgtaaagc attgcgcgtt cgcgtgccga ttaggattgt
    33181 ctaacggatc ccctttttgg ttcttctctg gtcgagcatg atagatcaaa atatcaaagc
    33241 acccgtcttc tgaaaccgta aacgagttgt gaccaggacc aaattgctta tttttttcag
    33301 aagaaacgaa tactggctcc gataatttat gccatgattc ttttaataaa agattcttgt
    33361 gctcatcagc ccacagcagg cccatggcat agttttcatc tgttgcacta ccagaatacg
    33421 taatgaatat tttcccattg cgagtaagga ctgctggacc ttcatttact gaaaaacccc
    33481 gtttttccca ttcatactca ggtatagaaa ggaggatctg cttccccttt aacgtccaag
    33541 gattatccat ttcggataga taaagattag aattcccagt aatttcagga tcttgttggg
    33601 cccacacata atatagcttt ccttgagaag agaaagttgt tccgtctaaa ctgaaagttt
    33661 cccttttcgt ttttatttgt cccttttcta tccaatctgt attcattgga tctatatgct
    33721 gattttcaag tacgaacatg cggtgatgat gagattcatc acgtatagtt ttatgattgc
    33781 ttgcagcaaa gtaaatatac cattttccat tgatataatg gacttcaggt gcccagatca
    33841 attcactcat cggtccttct tcatgagcct gccatacaat caggcttgca gcatgttcta
    33901 attcattcag tgactttgcc cttcttaatt caatcacttg gtagcctgga accgatcctg
    33961 taaaataata ataaccatct gtatgtttat atacccaagg atctgcccgt tgccgaacga
    34021 taggattatt ataaagtgtc ttcatcataa caaatttcct cacattttct ttattctaat
    34081 tacattccaa gagtattttt ctatccctac atttaattcg tcatgttttt ctattgaaaa
    34141 atagtttatt tcaggtttta ttttttctgg ttcttcacgt gtatttttgt ccaacagatc
    34201 gctactggtt aatgtgtagt gctctccttg atctagcaaa ttgaaatcat gttcaatcgt
    34261 tatcttttgt tgttcatttg tgcgattgat caagaaaata gtcagctgat tgccgttatc
    34321 tacgatcaca ctgtccacat aaggaacatt ttttatcttt tcacaatcat aaacagggca
    34381 aatgatttgt tgtttcaata cttgaccttt agcatatttc gataagtgtt gcatcacata
    34441 ataagttgga ttcctccatg cttgtccttt agcatctgtc agtattaaag gtattgtgtt
    34501 tactaacaat gattgacaac taatctttac gcgatctgcg tgtcgtaaaa tagccagccc
    34561 taatgaacca aataataatg tatcttccat agtaaagtaa caccaatcga tgggactacc
    34621 gacttcaaaa tccctatgtc ttttttccgg ttgggcatgt acattccatt catcaaacgc
    34681 tagatacatt gttttctcac ttctcaaata tccttttaca taatcacaag tagcaacgat
    34741 ttcttcaatt tgacgatcga atcgataagc ttttgcaagg tatgtcgctg tatcatcacg
    34801 ctcattttta ggaggtttag tcaagtcttc ttcatcatac ttatcaatat agttatgcaa
    34861 agctaaataa tctacattct cataagcttc ttctaatgcg atacgatccc attcagggta
    34921 cgatggtaaa cgtggcgtag agcttccaac taagattgtt tcaattgaat catccactaa
    34981 cttcatgact tttgaggctt catttgctaa cctaccatat tcataagcac tcttagcccc
    35041 cacttgccat ggaccgtcta gctcattccc taaacaccat aatttaacgc caaaaggctt
    35101 tttttgccca ttttttattc ttaaatcact ccagaaggtt ccttttggaa aattacaata
    35161 ttctactaaa ttttttgctt catcaattcc ttttgttcct aaattcaccg tgaatatcgg
    35221 tttcgcttgt acatgactga tccatttaaa aaattcgtgg agtccaaaag aatttggttc
    35281 tatacctcgc catgctaaat caattttttt tggtcgttgt tctttcctac ctacagtatc
    35341 cacccaatca taaccagatg taaagtttcc tccaggatag cgaatgacac ctaattctaa
    35401 ttcctttaca taagagagga catcttgtct aaacccgtca ccatcagctg tttcatggcc
    35461 cggttcataa atccctgtat agacgacact tcccatatgc tcaacaaatg agccaaacag
    35521 ccgagaactg atctctccta ccgtaaaatc ctctctgatt tttactttca cttcttcgtc
    35581 caacagcttt ccctaccttt catttcctat agtcaagata atagatacaa gtttccatac
    35641 gccaccagca aagataaaaa taaaaggagg gaaaagaaat atgagcagta caaatcctaa
    35701 taacaatacg caacaaagaa tatttctcaa aaaatcaaaa aatactttcc atgcactttg
    35761 ttcaaaaatt tgtaaaaatg tgatatcttt gttttcagaa atcacatata tccaggataa
    35821 aagaaacatg gaataaataa gtaaaactac atatccacta attgaaagta cgattgtctg
    35881 ttcttctaat aattgattaa caagaaaata aataatgatc gttaacagac taaggaacaa
    35941 gttcttacca aaatgttgct ttattccttg aaagaaaaaa taaatgatat ttcctgatcc
    36001 ctcacctttc cattgcgcca ttacataaaa aacagcacat gtagcaggca cgatagtaat
    36061 aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag aaaccacaat
    36121 caactgtcca taaaatttag tctcaactat tttcatcttc ctcactcttt cattccagac
    36181 atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag taatggcagc
    36241 attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg ccctgtaaat
    36301 aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat caatggataa
    36361 agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag agtaggtttg
    36421 ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc aatgcgtgct
    36481 gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa gataccaaat
    36541 gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc aagcaaattg
    36601 acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt cagcaaaacg
    36661 aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata ccccgcaaga
    36721 gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt atttttgatg
    36781 taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt atagctatct
    36841 gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga agaaataatc
    36901 agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat cgttcgaatg
    36961 atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga gctttctggt
    37021 gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt acacattagt
    37081 ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg atgcatagcc
    37141 caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg tttctgtctt
    37201 aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca tcgaaccaat
    37261 cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg taatgttaaa
    37321 aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag agggagagat
    37381 tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc aaacagtcat
    37441 gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga tcggcaagcc
    37501 gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca tagaaaaaat
    37561 aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac gacaaaaacg
    37621 attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga taatttgtgt
    37681 tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg ctcgttcatc
    37741 actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa agaaaatatt
    37801 caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa ataataataa
    37861 aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat tccaatattt
    37921 ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata caatcttggt
    37981 ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat aacacctatc
    38041 tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta tcctgtataa
    38101 agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt tcatgagtgt
    38161 ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat cgttattgat
    38221 cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt gtttcgataa
    38281 ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat ccaagtaggc
    38341 aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc aatatttcaa
    38401 aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg catatcctac
    38461 gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg tagtcacatt
    38521 ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga tttcaatggc
    38581 tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt ctggaccagt
    38641 cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct caggagacgc
    38701 aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta acatccagtt
    38761 atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt tactactatc
    38821 agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt gttcagtatc
    38881 taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt gtacctgcat
    38941 ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt ctttaaaatc
    39001 agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg ctccgttttc
    39061 tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt ttttagaaga
    39121 aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca tttcaatttt
    39181 gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata tttcaccatc
    39241 agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat cagattctgc
    39301 tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca aagagccaat
    39361 taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga catctgacca
    39421 cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct tttacatttg
    39481 ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt gtatcaaatc
    39541 cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag tgaacagtta
    39601 gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg tcatttatta
    39661 cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag tttgctgaac
    39721 gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata aatggataat
    39781 agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca ataacgttta
    39841 ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa gtgattaata
    39901 gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa ggaggagcaa
    39961 tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata ttccattcat
    40021 caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta tcgcacatcg
    40081 ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa tgagaaagat
    40141 catttttttg gttgccataa tattgatgca gagacaaata atctatttga tcgtacgctt
    40201 gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc gaacttccgc
    40261 ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt tcctctgcta
    40321 accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc atttcattcc
    40381 ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc cttaaatcac
    40441 tccaataagt tcctttagga aaattacaat attcgactaa attacgagct gcatctactc
    40501 cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga caccagttat
    40561 aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa tccaaccttc
    40621 taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac acaaaatttc
    40681 caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg acgtcttggc
    40741 gaaatccact tttattagct gatggatgat ctggctgata aatcccttca tatactgctc
    40801 gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct acacgcttga
    40861 cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata catgaataat
    40921 acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt ttttatcgat
    40981 tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa cttttattaa
    41041 caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca actacaaata
    41101 aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat caagatcatc
    41161 cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact tggagtgagc
    41221 agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat caaaacagaa
    41281 aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat tagttttcca
    41341 gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg tcactataca
    41401 aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat cgggaaagtg
    41461 gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct ctggtttacc
    41521 agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac attggagatg
    41581 ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa ttggccttca
    41641 gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc tggagatttt
    41701 gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa tcaatacggc
    41761 ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga acccttgtca
    41821 aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg aatcgaagtg
    41881 aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt cggtaattac
    41941 gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct attttataaa
    42001 acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt atttccagaa
    42061 atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc accatgcttc
    42121 gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat caatttcatt
    42181 atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt caagatctgc
    42241 agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca attgtttccc
    42301 ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac caaatttcgt
    42361 gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc ctgctctttc
    42421 tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc ctttgttaaa
    42481 atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa cagctggttt
    42541 gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt ttgcatcttc
    42601 ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt tttcatcttt
    42661 tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta aagtagaatc
    42721 ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt tcaaatatgc
    42781 tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg gtttgacacc
    42841 taattcattg ataatttctg tctgcaggct catttattct cctcctatgc ttctgtatga
    42901 agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt ccagcattca
    42961 gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc ttcccatagt
    43021 gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa ttcgtaaact
    43081 ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc tcgaacagtt
    43141 ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc tcgagggtct
    43201 tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg agtgatgcgc
    43261 cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa cttgatcgta
    43321 tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc accaagggct
    43381 ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat tttagctttt
    43441 tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata gatttttgct
    43501 tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata ggccatatct
    43561 ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt cgccacgcga
    43621 atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa cacgcagtct
    43681 ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga ttggactaac
    43741 gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg tacattgctt
    43801 gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc atccagttct
    43861 tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga tttgatacga
    43921 gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc tgtttctact
    43981 aattggcagt gcgctaaagg cccttccact tggatcaatg gttcatttgc aaaaactagt
    44041 tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa atactccaaa
    44101 aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc attgaacgtc
    44161 agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta tccgtggtta
    44221 aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg acctaattcc
    44281 cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa actgtcgtct
    44341 gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc ctacccatta
    44401 taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag cacatgtttt
    44461 acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc ttattggtat
    44521 ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac gaagaaatta
    44581 gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca atcgtagccg
    44641 ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa tcaatggcaa
    44701 aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa agaaacggat
    44761 ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat ataccttgcg
    44821 ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag taagaaagca
    44881 gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc ttgtttttta
    44941 ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg ttattaaata
    45001 gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg tttgaattgt
    45061 attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc ttctcgtgtc
    45121 atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt tttcttcgta
    45181 ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg tgttcgatct
    45241 aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc cactacttta
    45301 ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag cttcatctca
    45361 ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc atctttccta
    45421 gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc ttttatcact
    45481 taatagtata acataatttc atgagaaaaa aatacaattt tttcttgacc atctcgttac
    45541 gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca ataaagaaaa
    45601 tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag attggactgc
    45661 taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa gaagtcgatc
    45721 gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat atccaagagg
    45781 tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag caaatgttgc
    45841 tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca cttgatatgt
    45901 acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa caacaaaagt
    45961 tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga aaaaaaaagg
    46021 ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa gaaatgcaaa
    46081 ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca gaagatgaaa
    46141 gcttagcaga ccgtatcttc caagctcata agaagtggtt atcttacagc tggcctgaat
    46201 atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa cggttcactg
    46261 catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa attatccaaa
    46321 aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga cctaataaca
    46381 aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct ccattctttc
    46441 acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat aaggtatttt
    46501 cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc aagcttccag
    46561 atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat cgcgtccaat
    46621 caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa ccatatccga
    46681 atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt gttttccttt
    46741 ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa aaagttgatg
    46801 acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc ccaacgtgat
    46861 gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa ttgattgttc
    46921 tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa aaactagagg
    46981 tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg taatgatcaa
    47041 tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt ctttctgata
    47101 gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa tgatcccact
    47161 gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa tgcttttcgt
    47221 ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt ctttcatgac
    47281 cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga ttacacgtga
    47341 aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg ccactgctgc
    47401 ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg accgcattca
    47461 aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc ccaatatata
    47521 tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt cctattcaac
    47581 ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc ataaaaataa
    47641 ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc tccttttgat
    47701 actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg ccaaagaaaa
    47761 gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata cattataatg
    47821 atactgtaaa tatatcttta ttattagtga atggatattt acttttaata gataaaatat
    47881 tataactatt aaaaataact attttcatta taattacaca caaaaaagag cgtgagacaa
    47941 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacagcggaa gcagaagcaa
    48001 ctccttcgga aataagctga aattcacaaa aatttgaaaa gcaatttccg tgaatttctt
    48061 cttatttctt ggagttaaac gcttctgttc cagcctcttt ttatctgtct ttcactaatg
    48121 atcagttgta gataagcaag ttgctttttc ttacatcata ccgcccatca ttgatggatc
    48181 cattgcagga gctgctggcg ctgctggttc tggtttatct gcaacgactg cttctgtcgt
    48241 taataacaag gcagaaacgg aagcggcatt ttgcaaggca gaacgtgtta ctttagttgg
    48301 gtctacgata cctgcttcaa ccatgtttac ccattctcca gtagcagcat tgaaaccagt
    48361 gcctagttcc acgttcttca atttatcaac aatcactgat ccttcataac cagcgttttc
    48421 agcgatttga cgaattggtt cttctaaagc acgaacaacg atcttgatac ctgttgccac
    48481 gtctccttct gcttctacag cagaaacttt gctgataacg ttcactagag ctgtaccacc
    48541 acctgagacc attccttctt ctactgcggc acgtgtagca ttcaatgcat cttcaatgcg
    48601 taattttaat tctttcaatt ctgtttcagt agctgcacca actttaacaa cagctacacc
    48661 acctgctaat ttagctaagc gttcttgtaa tttttcgcgg tcaaaatcag aagttgtttc
    48721 agcaatttgg tttttgatca attgcacacg agcttcgatt gcttcttttt ctccagaacc
    48781 ttctacgatc gttgtattgt ctttatctac aacaacttta gaagcatttc ctaagttttc
    48841 gattgttgca tctttcaatt ctaaacctag atcgtcagta attactgtac cacctgtcaa
    48901 aatagcgata tcttcaagca ttgctttacg acgatcgccg aaaccaggag cttttacagc
    48961 tactacgttg aatgttccac ggattttgtt caatacaaga gttggcaatg cttcaccatc
    49021 tacatcgtca gcaataatca acaatggacg tgattgttgc aagatttgtt ctaacaatgg
    49081 cagaatatct tggatgttag agattttttt gtctgtgatc aagatatatg ggttttctag
    49141 aacagcttcc attttgtcgt tatctgttac catatattgt gataagtaac cacgatcaaa
    49201 ctgcatacct tctacaacat ctagttctgt ttcgatccct tttgattctt cgattgtgat
    49261 gacaccgtcg tttccaactt tttccattgc atcagcaatc aaatgtccaa ctttatcaga
    49321 acccgaagaa acagctgcta cttgtgcaat ggcttctttt gaatcaacaa cagttgagat
    49381 attatgcaat tcttcgactg ctgcttttgt tgccaattcg atcccgcgac gaatgcctag
    49441 aggattagca cctgcagtta cgttttttaa accttcgcga acgattgctt gtgtcagaac
    49501 agttgctgtc gttgtaccgt ctcctgcaat atcatttgtt tttgatgcta cttctgatac
    49561 aagttttgca cccatgtttt caaaatgatc ttctaattcg atttcttttg cgatcgtcac
    49621 accatcattt gtgatcaatg gagagccgta agatttttct agtacgacat ttcggccttt
    49681 aggtcctaat gttactttca ctgtatctgc taatttatct accccgcgta acatagctgc
    49741 gcgtgcgtct tctgcaaatt tcaattcttt tgccatgatt gattcacctc attgattatt
    49801 tttgattatt tttttatctt ccaaatttac tcaacaatcg ccatgatatc ttttcctgcg
    49861 acgatcagat attcttttcc ttcgtatttt acttctgtac cggcgtattt ttcgaacata
    49921 acttggtcgc ctgcttttac agcggcagga actttttcac cgttttctaa caaacggcct
    49981 tcaccgactg caacaactgt cccagtttgg ggtttctctt tagcagcaga agctaaaacg
    50041 attcctccga cagttttttc ttcttctttt gcgacttcga taatgacgcg atcacctaat
    50101 ggttttaaca cgataaatcc ctccgataac tcttttttta atctgttagc actcttaacc
    50161 ttcgagtgct aacctacatt tttaataata ctcattctcc ctcttttttg caagctttta
    50221 aatcaaagaa aagaaatttt attctgacag ctgcttattg aaattatgat ataattgaaa
    50281 tcaatcgata taagcttgcc ttgcatgctt gttatccctt aaaaggagga attacatgtc
    50341 tttaaaaaaa tatagcttcc tcagcatttt ttgctatggt ctaattttta tctcaccctt
    50401 gatcctagct tcgataggac ttgtaaaatc tacgtctgaa ttgatcacag caactgcagt
    50461 catgtatata ctaggcgccg ttgtcctagc tattttttat tttaagcaac gtgaaccctt
    50521 agcgatcgaa tcagcggtaa aaaaagcttc tgctccaaag attgttattt atggattggt
    50581 tggaatcttt gtcgcattga ttctgcaaag catcgctgtc atgttagaat ctgtattgtt
    50641 tggcaaagca accccttccg agaatacaca aaatatcatc cagatgatca tggaagcacc
    50701 cgcttttatt ttggcgacaa ctgttgctgg acccatcatg gaagagttcg tattccgccg
    50761 cagtatactg gggatcatca gtcgatattc aaatttttgg gtcggagcag tgatcagctc
    50821 tttgctgttt gcgtttgctc ataatgatgg tcatctgcta atctactttt tcctaggttt
    50881 cttcttcagc ctagagtaca aagcaactgg tcggatctgg acatcgatga tcacacacgt
    50941 aggaatgaac acattagttg ttcttgttca attagctgtc caaaaagggc tagtataaac
    51001 atgactataa atactcctgt catcctagat tggtgatttt cccaatctaa agcgacagga
    51061 gtatttttgt tttttagtcg ttcatctttt ctgctgctcc atcatttttt gtctgtcttt
    51121 cctttttgca gtttgcagaa tctatttttt tcaaaaatgg gaaataaatg aaaaaactaa
    51181 ttgacaacac gataccttgt aaaatcgctg caggcactcc gcctactaag aaacccgaga
    51241 ggatcggcgg tgttgtccaa gggacttgga ctgctgtaaa taaaggaacg aatccaaaat
    51301 ataaagcgga ataggtaatc aatcctgaaa cgaccggtgc gaaaataaaa ggaacagcca
    51361 tcatcgggtt catcacgatc ggtgtggaaa aaataattga ttcattgatg ttgaaaaagg
    51421 ctggtaaaag agcaagattt cctaattctc tgtatttctt cgatttcgca aaaaccgtca
    51481 taaaaaatac agcccctaac gtcaatccag cacccgtaac cgtcatgaac tgatcgagaa
    51541 attgctgagt aacgatatgt ccgccatttg ccaccgtcaa ctcttgtcct gaggctaaga
    51601 tttctgcatt tgctaatgaa ttcgcttgca agacgggact aaccaaccca ttgaccatcg
    51661 cagatccatg aagaccaaat aaccataaaa acggaacaaa aaaacctaat aaaagcacac
    51721 caaacaacgt gtctatgaac gattgaatgg gaagctggac atatgtccat actccttgaa
    51781 caacagtcat tctgaacaaa tgttgaaaaa ccgctgaacc gataagcgta aaagtgacta
    51841 taacaatgat tggaatcaat gaagtaaaag actgccaaac attttcaggt atcttctctc
    51901 tttgcttcca ccctttcgca agtcttacta aacgtgcata gccccatccg atgatgagcc
    51961 cagttgtaac tgctcctagt atcccttcag cacctgtcca gacagtatct atctgagtat
    52021 ttagtggctg aataagcagt agataagcag acaaggctgt tatgccgact ggtaagcgat
    52081 cgatgtcttc ttcttttgca taagcgtatg caatggcaaa aacgatccaa aaggctatca
    52141 catcaaatgt agcctggtat acttgtgtaa aatacataga aaatcctgtt ttgtctatcc
    52201 actgagcgat gtaatccaca ggaaaatgag caaataagaa aaacagcgag ccaacaataa
    52261 ttattgggat cgtgtaagtc attccattac gcaaagcagt taagggtcta agattcacaa
    52321 cagatgttat cattggtaaa aaggcacgat ctaaccactc tttcatttct tatctccttc
    52381 aacttctatt tttatcaatc agttttctta atttaactat acccaatgat cacgaaccat
    52441 gaaaggaatg cgcactgagc ttttcaaaaa tcggattctt tgacgaatat tcagcaactg
    52501 cttacaatgg acaggaataa aaaaggaggt tttttatgaa aattgcactc attggagcta
    52561 ctggccatgc aggttcattt attttagacg aagcattgtc cagagattta gacgtgacgg
    52621 caatcgtgcg tcatccagaa aaattgccat cagatgttcc gtttatacaa aaggatttat
    52681 ttgagttgac aactactgat cttgcatctt ttgatgttgt cgttgatgct ttcaacgctc
    52741 ccaaaggaaa agaagaaatg catcaaactt ctttgtccca tttgattgag atgcttgaag
    52801 gaaccgatac acgcttaatt gtcgttgggg gtgcctcttc gttattctta gatacagaaa
    52861 agacgactcg tatgattgac caagtaccta aaaatgcacc cttctatcca acagctttca
    52921 atatgtacga aggattgtta aaattgaaac aatctaaaaa tctacattgg acttatatca
    52981 gtccagcttc tttatttgat ccacatggca aacgtacagg tacttatttg ttaagtgatg
    53041 attatttaca aagaaacgct gctagcgaca gtacgatcag catggcagat tacgcgattg
    53101 cattagtaga tgagatactg gatgagaaac atgaaaagca gcacatcagt gtagtcagtc
    53161 gataatacgg ttattttttt aatatgctaa aaaaataaaa atagaagata aaaccaaccc
    53221 tgattgattt tatcttctgc tttttatatt tttattgatt gaactgttta aatcgaaaat
    53281 agctcagttg cttcatctgg atctgtatca tagatttcaa aatcatgtcc aacgccaaaa
    53341 tctttttctt tcaaaacatt ttccattgtt aaatgagcaa gttctttcat attgttttcc
    53401 ttgctaagat ggccaagata gattcgtttg gtccgattac cgatcacatc agtcatgaca
    53461 agtgcaccgt cttcgttgga aagatgtcct ctatctccta aaatacgctg ttttaaattc
    53521 cacggataag gtcccatgcg taacatctca agatcatgat tactttccat caaataacca
    53581 tcggcatttt caatgacacc tcgcatataa tcactgcaat atccggtgtc cgtcaacatg
    53641 acgaatgacc gattttcttt atggaaacga taaaattgcg gagccgctgc gtcatgggag
    53701 acgccgaaac tctcaatatc gatatcgccg aatgttctga ctttccccat ctcaaataga
    53761 tgtttttgtt ccactggtac atttccaatc agtggttcca tcgcttccca agtctgctga
    53821 ttggcaaaaa catccaaatg atacttacga gccaagacac ccacgccatg tatatgatct
    53881 cgatgttcat gcgtcacaag tattccatct aattggtccg gtgtccgatc aatttgagcc
    53941 atcaaggaag tgattttttt accgctaagt cctgcatcga ccaaaagccg ttttttttca
    54001 ctttcgatat aaagtgaatt acccgaactt ccacttgcta ggatactgat tttaaaagct
    54061 ggtttttctt cagccatttg actcctactt cccttcttac tttgtaaact tttttcatta
    54121 tactcgcttt tttattgatc ttccactttt ggtacagtat tgtttgtcac gatcgtattg
    54181 ctgaaagcgt tgacgctctc aatttggacc actttatcgc ttgtttcgat cgctacatgc
    54241 caaacaggaa catacacatt tttttcccgg actttcagaa tacaggaata agctagctga
    54301 cgccataaaa tttttgatcc tcttggtatt ttgttattga tgtacaatgt attgattgct
    54361 tcctcttccg tatacagttc cgtcttttcg cgcagctgct cgatatcaga taaatgcgtc
    54421 tgcatgtatt tcgtgatgct ataatcatta tcgttttttt ctaaagaaag aacgattttt
    54481 gctgtatcat cattgaatgg gatgccttca tactcttggc ttgcttggat ttctagtggt
    54541 tcttcttcta aatgagaaaa gtttttcgtg tacacataat cattaccgaa taaaatattg
    54601 tctttgttag ataaaaaatc ttccaaggaa ctactaattt tatctggatc gatcacgttc
    54661 ttttcagcat ctgaactgga taaagatttc gtcaaaacat caccgtctaa aaacacacca
    54721 cttgccagca agccgctttt accagccttg cgataattcg ctaatgaagt gctaagattg
    54781 gtctgctccg cgctaagata atagccttgc ttgttctcag acgaaatctt ccccgtgtaa
    54841 gtgatatcgt cgctagccag acgttgttgg attgattcag tctgattaga gcgaatgaca
    54901 ttgttttctt ggtataccgc gtcatgataa ctgctgaata aaaacacatt caaccctaaa
    54961 aaagcgacga aaaatatcca ttcgattttt ttgaaatcca attaattcgc ctccaatcca
    55021 ggtaattttt ccagaaggtc gttagctgaa taccagttat ctttatattt cacataccat
    55081 tcaggtaaga gatcaacgac acgattcgtt tctttgacat tttgccatgt atagccaacg
    55141 atcactgaac caatcttgtt gctatctgct cccttagctt ttaactgctg gatgatttca
    55201 ttcgtacttg caagttctac ttcttcgtct gaaggtatcg gcacttgaat cgtattcaaa
    55261 ctggtttgga tattcacttg cacagaacca ttcgtttcac cgccaacttc cacaccaatc
    55321 tgtcctctgc tgtctgtccc aaaaaccggg aagccttcca cgaatatccg ataatcgatc
    55381 gtattgtcac tgcggtcaaa atatctgagg ttccctaaag aactgcctaa tttgctaata
    55441 taggggaaac tttcagaaaa tacactagca ttttcttttt tctctggcag ctctccacga
    55501 aaatcaacta cttgcgtttc cgaatggata gacattgttt cattcccacc gtaaaaaatc
    55561 aattcattgc tttcatcatt atttttcacg ctatctggtt tctggaaaaa agcatttcta
    55621 aaaagtgtat agggttgctg tgacaggata taactatact tcttcagttt gatcgaatgt
    55681 ttcgtagcat attgcgtgtc gatcgtcgat ggttctgttg tcatttctgt ccattttgtg
    55741 tcttttgctg ttaattcttt attgatatct gtccaattca acgaaatatt tgcttcatat
    55801 acgagatggt tcgaataatt caaaaatcgg atttttttat ttccttgatc gaattgtatt
    55861 ctagtaaaat acatattttc gctttctttt gccaagttcg acacatctaa atctaaatca
    55921 aatgcttcct tgtattctct tagcaaaaaa ggcgcattat aggccaactc aaaaccagag
    55981 ttcagatttt tcacctgttc aaactgtgat ttgtctcctg aaactacttc agaaagcttt
    56041 ccaaatcttg ctttatcgat gatcaattgc aatcggtaca cgagattttc actgttggtt
    56101 tcttggatca ttcccgaatg gtgccatgta acatgaagcg gaagaaagac ttcggaagtt
    56161 tttcgattgc tttgagactc gatcatttga gtgtttgtct catctacgtt gattgaactt
    56221 tttcctgctg ggctcagcca gattgcataa gagaagtata tgcttaacgc aaccatcaaa
    56281 atgagtccta tacgaacgac tttttcagag attctcattc ccaccattcc tcctcataag
    56341 gttcatatgg cagcgagata taaaaagtcg acccttttcc ttccttgctc tctgcccaaa
    56401 tagcgcctcg atgcgcctta atcacttctc tagaaatagc taatccaagt cctgtcccac
    56461 cttgtgctct tgcacgtgct ttatctactc gatagaaccg ctcgaacact cggttcagat
    56521 cttttttagg aatccccaat ccttgatcgg tgatacttaa aatcacgtta ttatgcgttt
    56581 ctaataagcg acaagtaatc gttcccccat ctggtgaata cttgatcgcg ttattcatga
    56641 tattatcgac tacttggatg attttatctg tatctacttc gacccaaaga tctctttgcg
    56701 taaattcacg acggatctta taattttttt cctgatttcc caccatcata tcaaaccggt
    56761 caagaacaaa attcactaac tcgttgaaat tgacatattc taattgaagc tgggtattac
    56821 ctgtatccat gcgagataga tttaagaggt cattgatcat tcgaatcatt cggtctgttt
    56881 catctagcgt taccttcaaa aaatttggtg ctacttcctc gtctttccac gcaccttcgc
    56941 tcaatgcttc gatataacta cgcatacttg tcaacggtgt acgaagttca tgggaaacat
    57001 tagagacgaa ttcacgacgt tcccgttctg ttttttcttg ttctgtcaca tcatgcaaga
    57061 cagctactaa tccgctgata aaacctgatt cgcgacggat catagaaaag tctactcgca
    57121 agatcatctg atcactttcc aatgtactgg ttgaacggtc aagtaccatt tcgtttggat
    57181 cttctaataa tttccgcaac gtatattctt cttcgatatc taaaagtgtc aaaatcgatt
    57241 gtccgattgc ttcctcgttt ttgatatcta gcaaggaaac agccatatca ttgatcgtaa
    57301 tgactttacc cctgcgatct gtcgcaatga cgccgtctgt catatgggat agcacgctat
    57361 ccaaacgatt gcgttcagct tccattgtat cttgagcttc ttcaatacgt tcagctaact
    57421 gattgaaggt atcagccagc tgtccaagtt catcttgtcc atgcactttg actttccgac
    57481 tgtagtctcc tctagcgatt cgaatggctt gttctctcat ttcaccgatc ggctgtgtaa
    57541 tcgaacgagc aactaaaaca gatacgatca ttgaaataaa tgccgcaatt agtgaggcag
    57601 taaagaaaat gactgctgtg ttattgattt ccgaatattt ttgttcgata ttacttttga
    57661 cgtaaagagc cccgataacg gcatcgccgg tcggggacag gatcggttga acattgatat
    57721 tcacccgttt atcgtcgtta tctaaagcaa cataacgttt agtcgtgaaa tcattgatat
    57781 caacataatc atttttcttt cccacagcgc tttgttcatt gacatcggtt gttcctcgga
    57841 tgatcccttt ttcgtcaacg acccgtattt cgatgatatc gctagtcgca ctgttttcaa
    57901 taaatctttt gatattcgca tttacctctt catcatctgc attatctttt cgattcaatt
    57961 ccgggctgat tgttgttgct aatgattcca ccgtttgatt catatcttta ataaatgtat
    58021 tgatcgtgga acgttctaaa ccacgtataa agtaggcacc aataatttcg atcgagatca
    58081 ataaaatcag aataaaggta atagcgatct taaaattgac tgatcgaaaa aagcggactt
    58141 ttcttttcat ccaattactc ctgttctggg ttacgcaaat agtaaccgac accacgacgt
    58201 gtcactaaat aatttggatg gcttggatta tcttcgatct tttcacgcaa acgacgtaca
    58261 gttacatcca ctgttcgtac atctccaaaa taatcataac cccaaaccgt ttgtaataaa
    58321 tgttctcttg tcatcacttg tccaaggtgc ttcgccaagt aaaagagtag ttcgaattca
    58381 cgatgtgtta actcgattgt ttctcctcgt ttcgtcacca tgtaagcttc tggatggatc
    58441 gtcaaatcac caatcgtcaa ttccgcaggt gctgcctctt ctggttcctt cgcagccgtg
    58501 gcaccgcgac gaagatttgc tttgacacgt gcaactaatt ctcggttgga aaatggcttg
    58561 gtcacgtaat catcggcgcc taactctaag cctaggactt tatcaatttc agaatctttg
    58621 gctgttacca taatgatcgg catatcataa gttttgcgta cctcacgagc aacttctaag
    58681 ccgtccattt taggtagcat caaatcaagt aaaatcaaat caggttctac ctcagcaact
    58741 ttttccaagg cttcttcccc atcatatgca gtataaacgt catagccttc tttggctaaa
    58801 ttgaatttga cgatatccga aatcggcttc tcatcatcga caactaaaac ttttttcata
    58861 aagagccacc tcttatatat tattgtcata ccttctcatt ataccgtatt tctgcttttg
    58921 tttcatcttt gcctataaaa caaaagagaa aattaaaatg aaagtgcaaa atactttatt
    58981 attttttgtt ctaacttcaa taaaaaagga aaacactgat tttcacctca gtgtttcctt
    59041 tttttgattt atccttctaa aacttgtaca ccgacaccca ataatcccgg accagtgtgg
    59101 actactaatg ccggagaaat ctggccaaag tagatttggt ttgcttgtgg gaactctctt
    59161 ttaagtctcg cttccatttc aattgcttct tctttcgcat ccccatgggc aacagctaag
    59221 ttgaagacct ttgcattacc gattttttct ttgacgtaag caaccgtttt atccaaactt
    59281 tttttacgtc ccctagcttt tcctactgtg taataaatcc cttcttcatt acatgagatg
    59341 attgggttaa gctttaaagc ggttcctaca atagaagcaa ctaaaccgat ccgtccacct
    59401 ttttgaagat attccaatgt cgcaacatta aagaaaactt ttgttctttc gactaactca
    59461 ttcagattac tgatcagttg atcccattct actccttctt ccagccattt tgctgcttgg
    59521 atcgcagaaa aacctgcacc aataccaata tttttcgtat ctagtacata tgcttccaat
    59581 tcttcttgct gttgtgcaat taaacgaacc acattatatg tcccgctcaa tccactggaa
    59641 attgttaccg caagtacctt ttcataaccg tcttttttga tttgctcaaa gatttctgtg
    59701 atcgactcac catccggcaa agatgtacca gggatttcct ctggcaaacg ttgatagatc
    59761 tcttcagggg taatgtcaat tttatctgta tatacctgat ctttataaat aattttcaat
    59821 gggatcatat acatctcgta tttttttatc aattcttctg gaacatccgt acctgaatct
    59881 actaaaattg cgattttatt gtttttcatt tgttttctcc tcttttaaat attcggtttc
    59941 tagaacaatc gttttttccg caagaagttt cattgcaaac gataaagttg ccgctcttac
    60001 agcaatatat tctacagggg ttgcctggtc gaatttttgc ggatgagatt taccttgtgc
    60061 taattggctg accatccaca cagctgcttc ttgttcatcg caaaatagat tataggcttc
    60121 acgaattcct actgtttttc cttggaacaa tatcccttct ttgatttcag gaatagtcaa
    60181 tacttgtttc aacgtagtga ttgcaagtaa aaatgctacg tgttctttgt tatatctttt
    60241 tttaactggt gctggtatca aacctagttt aacgtaattg tttaccatag aagaggtaag
    60301 caatggatgc ttttctcctt gtatcacagg tgaaagataa cgatcaacta acgttctgac
    60361 ttggtccata taaagttcta agtcagggag ttcttcccag tgaggcagac ggaatgtttc
    60421 tagttccttc ccccactcca ttaattgctg acgcattttt tccatcataa ccgctccttt
    60481 tttcatttca taaacatgat atcagactta tgataaacat tcaatctagt tgctttaact
    60541 aggtgatttg attagcggga ttctatgaaa acaaaaaaca agaaggctaa gccttcttgt
    60601 cttttatcgt taagaacagg agacccgccg gggagacggc gggaaaggag taaaaaatga
    60661 aaaaagtgtt agggtttgtt ctcttgcaag aactttgttt gttggtatgc ttatataata
    60721 gcgagcaaat gtgaataatc tatgaatgat ttcctataag gaagtaaaga tttttctgat
    60781 tttctttaaa tgtagtcttg cattttaaaa ttcttagtgc tactattatt aagtactttt
    60841 tgtacgggcc gttagctcag ttggtagagc agctgactct taatcagcgg gtcgcgggtt
    60901 cgagcccctc acggcccatt gggtgccaaa cccacggaac aggtaaatgt tggtgcgaaa
    60961 gcatttcgaa aacatttacg ctgttctttt tttatttttc aaaataacta gggcttttta
    61021 tttttaactc aaagtccact gtagcccttt ggactttgag ttaaaaaaga agcataatta
    61081 tgaacagtaa agtttctaat ataacaataa ttcgagaagc tttgcaaaat catgctgcca
    61141 atgaactctc taaacatata ggattaaatc taagtactat aaaaggttaa aaagtgaaga
    61201 atatttaata gaaaaactaa atttacttgc tgctttcccc ttttccatta atacaacaat
    61261 cagagagtgt ctttttttcg aaaaaattag aataaataaa agacacgtag tttttttatc
    61321 tacatgtctt ccatcgacta caagttatca tttctcaaaa cgtatttagc ttttaattga
    61381 ttaatcgttt cacgttgtct acacattgcc taattaagat tttcttatta gaagcatcaa
    61441 tcccgcaata atacctaaaa ctccaggaat tacccacaat aatgttaaaa gaaaaaatgg
    61501 aataatagat aaaatgagta aactaatacc atagaccact gttttttgat tttttcttac
    61561 taaaaaacct attatgaaaa tcattatcga aaaaactagg gtaattcctc caaataaaac
    61621 aacattcccg cttagattga ctaacatatc tatatcctta ctggttagtt ctgtagtatt
    61681 taaagtagtt gaatcaatag aagatagaaa cataccaccc atcaatgcta aaagactaca
    61741 taaaatccct gttattccac taattaaaat caaaataaac tctgtttttc tcttattcat
    61801 ttaattctct ccagattaag tgttttagaa ttagaaattt tttgaccata gttaatagct
    61861 tctaatgaac gaataacaac cactgacgtg ttagaaaaat aatccccaat atgttgtttc
    61921 ttgggcgtga aagcagccac caaataccca atttgaaata caaaattttt taatataaac
    61981 ctacatatac actcacgaat aaagatagtt tgccaactta gctctttttc ctcaaagctc
    62041 actactctta tcccaaaaat cattttccca attgtttgtc ctgaattcag cttagtcaaa
    62101 agtacaaaat aggttaaata aatagctaat gacgctatac cataaaaagt aataatggat
    62161 ttgtcagatt ccagtcccat gattttgtaa aagagaccta tagtagcatg ggtgatgatg
    62221 ctaatacaaa ttaaatcaat aagaaaagca aaaaatcgta accaaaatcc cgcaaataca
    62281 taattaggca aagtttcaat gccactcttc ttattcattt tatagccctc catagtaata
    62341 cattggtttt ggagtatcag aaaatccaag tttttcaaaa actgaaatta cacgatctga
    62401 tgtagttgcc tttagccctt gccattcagc aatcttatta cctaaccaag aagaagcaaa
    62461 gccagttgtg tcatttttat attctataac cgtcgcatca gttaatttct tctctttttt
    62521 tagggaatct aatgcatctt cagagtaacc aatttgatcc accaacccat tttctactgc
    62581 ttggttacca tcataaattc ttccatccgc aagttctttc actgcattag tatccatatt
    62641 tcttcctttt gctacaacat tgacaaaacg atcataagca ctcatcacaa attcctgtat
    62701 aactttattc tcttcctctg aaggtttgtg ttgaggtgac atcatatctt ttaatgcacc
    62761 acttttatac gtcgcatcag ttacgccaag tttttctaat aagccagaat aatttaaacc
    62821 agaaataatg acaccaattg atccagttgt tgtttcttcc gtagcaaata ttttatctga
    62881 accagcagaa atgtagtacc ctccacttgc cgctgtattt ttaaatgcag tatagatagg
    62941 aatatctagc tttttaattt ttgccatttc tttagcaatc tcagcacttt catatattcc
    63001 tcccccaggt gaatttactt ctaataacac tcccttaacc gctttgtctt cttgaatttt
    63061 ctttagctgt gttaaaaaat tctgatggtt atattgttcc ctactaaaaa gattgctttc
    63121 acctgtatct gcaataactc cattgacgga tagtttgaca atctttttat ttgatgcgcc
    63181 ttcttctaac gtttcttctg tgatttcgtt agatccgtaa aaaatcttat ttattcctgt
    63241 tagggttgta tttgatgctt cctctttatc ttttcctgga attagcgcga cgataatgga
    63301 tagtaacaat aatccgcacg ctactcccac agcaatccat cttcttttat tcatataaac
    63361 tcctcctata ttcttagtaa aaataattat tttttattta gaaacacatc gacaatttgt
    63421 tgccaatatg ttttttctcc tacaattaaa gacaactctc cagttaatcc ataacgaaac
    63481 ggaaacgatt gagttgtttt taacgttcct ttcactgcat aaaaaacacc tttctcagtg
    63541 gcagtagaat tttctgaaat ttcatctaaa gttccgtcga tcgtaatcgg agccccacct
    63601 ttttgatcca atttaaaatg aaccttcatc ccttctttaa tataggtact ttcattcgca
    63661 ggtaaaagtg ctgtaaattt catttttgat ttttcgtgga tcggataaat ttctgcaagc
    63721 actgttcctt tggctagttc tgcttgtccc tttgtttctt catttaaatg aaccgttcca
    63781 gatacaggag cttttagtat tccttttgaa agttgatcgt ccaaactttt gataactgac
    63841 tggttcttct cttgtttttc atttagctct gtaactgttt gttttacagt tgttattgct
    63901 tgttctagct cttgctttcc tttttccgtt tgactaattc tgtcattctc agaagtagtt
    63961 ggtttaacta atttagcttt ttctgactga tactgttcta cttctttttt tagttgctca
    64021 atttgttcat ttatgcttgc tgaaattgtc agtttcactt gatttttttg atcatcagaa
    64081 acattattta gttgttcttg ccaattctca tagtttgcca tcatttcttt tgaaaaatct
    64141 tttaatgatt gattattact ccaagctacc tgtacttgtt gccattcttg taatttacta
    64201 tctgaactct caatttgttt ttctagttgt ctttttgtct tttcgtatac ttctaattgc
    64261 ttttgatcat ttaattcact ttgcttcaaa gcgtagcgga gtgattcttt ttctgacaac
    64321 atgctcttta attgattact gtagccaaaa ctgtcatccg ttgaaaacaa attttttcct
    64381 ttacttatac tttcaataaa tagctgagcc atctttattt gttgagtaat acgttggttt
    64441 tcttgttcta tctgagcctt ttcattctct attaaagaac aatccaatct aaccaacaca
    64501 tcgtccttat gaacaaattg attttctttt aggaagtttt ccattatttt agcttctaat
    64561 ggcacttgta acttctctat tttttcgggg ttcaattgag ccgttgtccg aataacaacc
    64621 tcttttttag caaaggttaa aaacaatcca ataatacata aaaaaagaat tacagggtat
    64681 aacacccaac ggtagaagct atgatgttgt ttagtataga tactagaatg ttcgaaccaa
    64741 ttattattct gcataaattg tttccctctc ctagatttcc cataattttt gatagatacc
    64801 atcggcaaaa cgaagttcat cgtgcgttcc tttttctacc aaatgccctt catggagaac
    64861 taaaatttga tcacatgctt ttgctattgg taaatgatgc gcaataaaaa taatcgtttt
    64921 ttcttttaaa ttgaggagat aattcataat tgcatgttct aacaaggtat ctaatccact
    64981 agttgcttca tctaaaatta atatgtccgg attttttaat aaagcccgtg ctaaggctaa
    65041 tcgttgtcgt tgccctcctg aaagattatt tccaccttct tccaacaatg tctcgtaacg
    65101 taatggctgt tgattaataa attcatttag ttggactatc tcacaaactt ctattatttg
    65161 ttcgaaactt ggtgggctat ctaaaccgaa tataagattc tcaatgattg ttccactaaa
    65221 gaaaaatgac tcttgaggca aatatgtcac tcgatcgcgt aatatctgaa aaggaatgtc
    65281 taagtgatta atgtttccat aatggatcga tccttctgat gcttcataaa aacgaacaaa
    65341 taactttgca agagttgatt ttccagaacc actaactcca actatagccg ttttactgtg
    65401 cgaaggaatt gtacatgaaa tttcgttcaa cgttggggcc ttcatgctat acgagaatga
    65461 aacgtttttt acagtgatat cttgttgaaa taattgttca gaaagcatat attcaaaaga
    65521 ctggttcgat ttttctgaat caatcgcgaa aatttcattt aaacgattat ttgcaacttg
    65581 agccgtttgc attttcactt gtaaattaat aatgttttgt aaaggatctg tcaaaaatac
    65641 tagtaaagca ttgtatgtga taagttgacc tagactaatt ctattatcca taacaaaata
    65701 agaacctagc cataaaatta atgcactgct aattaattga atcaaatgtt taattccttg
    65761 ttgaatatta tcaagcgtaa ccgtacgaaa tgattttttc attaatttaa caaattcatg
    65821 gtctatacgg ttatatactt tctcttcacc gctatatgct ttaattgttt ctattccttt
    65881 aagactttct atgatactag aatttacagc tgcaccggct gccatttctt ccctgttcga
    65941 tttttcatag cttttcacga aagcgaatat tgcaactaca taaaaaggca aagagcatag
    66001 agtgattaaa aacaacgtac tattctgaat agctaacgta accccaacaa gcaacaccat
    66061 accaatatct aaaaatattg ataacgtagc acttgctaaa gcatcaataa tcttactggc
    66121 atcaagaaaa cgagaaataa tttcccctga ttttctcgta gcaaaaaaat tcattggtaa
    66181 agttaacaca tgtttgaaat actgaagcat aattgccata ctcattcgct gtcctaaaat
    66241 aataagaaga taactacgac tatattcaaa caatacccga aataaataga cagcgatcaa
    66301 gccaatggaa attatattta aagttgaacg tgcttgatta gggatgaaaa aatcaagaat
    66361 accttgaaaa taatatgagc ttcctatgcc aaaaaacgta atgaaaatcg atgctaaaac
    66421 gatgtggaat actaatcctt tttgtttcca aattataggc aaaaaagaac ttaatccagc
    66481 tactttttct ttaataggaa tataagtttc tctaggcata ggtaataaaa gaatacctgt
    66541 ccattctttt tgaaacgctt caatcgtttt tctatttttt ccattagcgg gatctgcaat
    66601 ccatagtacg tttcccttcg ttttataaat tacaacgtag tgcatatagc tgttatcaac
    66661 caatatatgt gcaattaatg gtaagataag atctctttct ttccagatct cactatctgc
    66721 ttgaatagcc atacaatcaa aagacaattt ttcaaatgtc tttttcaatc caaatgctga
    66781 agtaccctct aaatcagtcc cagataggtc ccgtaattta tgaatcggga tatcagtttt
    66841 aaaatatttt aaaatcatcg aaaggcaagc aacaccacaa tctttttcat cttgttgctg
    66901 cacaaaagga aatgatttta tcacttatct aacacaactc cttctaaaaa atttttatag
    66961 aaaaattctc aatatagctt taatacagtg aaaatattgt ctcataattc cacaaaaact
    67021 ttgaaaacag ttcttgaaca ctaacttttt cattcctgaa tcaaatttat tttggaaatt
    67081 ttactattca agaataaact tgataagttt caggaagatt tttactgtta atcaaatacg
    67141 tatgttacag tagcaccgta aaaaatatta tttaaagaag cgtgtttaaa catgcaaaat
    67201 gtaaaggaac taagtattgt ggaaatgcac aaactgttgg tggaggcaat aatgcttggg
    67261 gaaaattggg gcaagttgta ggtggactta ccacaggggc agtaggtggt gcaggtttag
    67321 gaacagcaat ttgcggacca gcttgcggtg ttgttggagg gttatatgga gctgtcgctg
    67381 gaggtgctgc agctggctgg gatgctcgaa aaaaataaaa aaggagaata agtagtatgc
    67441 atattaaaaa cacaaaaaca acatttatat tatcttcaga agagttgaaa aatattcaag
    67501 gtgggagtgc cgtgggagtt ttaggcacta ctttttctgg ggcaacagca ggagtaaaac
    67561 tttgttcagc cggaggacct tatgcaatag ctgcttgtgg tgtaggtgga gctttattag
    67621 gtgctggatt cagcatgtgg accggtgcgt aaacaattaa aaaatatcaa acctcaagat
    67681 tggtttgtgt cgattacgaa cataggtatg ttctttatct tttcaaaagt ttggaatgga
    67741 cagaactttt tactaaagct tcttgtgcta gtttttataa ttatattaaa tttttatctt
    67801 ttattaaagt cagataaaaa ttctttggaa atgtaatggt agagatattt ttacaaaagg
    67861 acttgcagcg ctgtagttgg tgctgcagga ggacctattt cggccgttac aggaggtatt
    67921 ggtaatgtac ttgtcggatg tgcattaaag cctgttcctg caagttaaat ttataaaaac
    67981 aggaaagtaa ttatctcaaa tcctatcaag tacaatcata ggattgcact tgacaggaca
    68041 aattttttaa ctaaaaaatg aaaaacactt tctaaaaatt agtagaattt gccaaatctt
    68101 tcgcatcttc caccatacat ttaattttaa ttccccttta tggtacttaa taaaaacaag
    68161 aaaagaacta ttcatttggc ccttttttgg ttccagacca tagaaatatt cctccagtaa
    68221 ctaatattgc tgttatgcac gtaactaata acagctataa aaattggtac aactttaata
    68281 ggattcagaa aaatttgcac tagtgaagga atctatttta ttagaaaaat gcaatctccc
    68341 taaagaaaaa accactaaac agtgctttct ttcaacttct ccttaatttt ttgtgctttc
    68401 cctaaagtaa agtttctggc caactctgaa tcaaaatata gtgaacgttt tttaaaatct
    68461 atttctttaa cgttaaagat atttactaaa cacgctcgac taattcttgt taacatagga
    68521 tatttctttt caagctcact aattcttcca taaaattcgt actgcccatc tttagtacac
    68581 aatgataatc tatgtggtaa ttttgaagct tctacaaaat aaatgtcatt tatatcaaaa
    68641 gtaaatgttt gagaacctat ggaaaaaaca aatgcttgat tcgtaacctg ttttgttgca
    68701 tctatccttt cttgcgctaa taacaataac tcaacaatct cgtttcgata ctcatctagt
    68761 gtttgatctt ttgttacaaa tcctaacgtt tcaactcttc tttttattgt tacgggtaac
    68821 atctcatcat gagtagttgt aaaaatgatt tttgcttgaa catcatattt tctgattact
    68881 tctgctaatt ctataccgtt aacttcatga tttaaatcaa tatctaagaa atatattcct
    68941 tgctttggtc ggaattgttt gaggtatttt ttaacttcta acggactttg tgttttcaat
    69001 actatcttaa atactttatc gtgaaaaaga atgaaattat caataattcg ttctaactga
    69061 tttaattgta taatttgatc ttcacataat attattggat aactcataaa tcctccttcc
    69121 ctcaaaacaa caaaataact tgagtagtaa attgatacgg atcgttttga tagttcacaa
    69181 acatattggg attcttttta ttgatttcct ctatactaga taaacctaac ccttgatgtc
    69241 ccttttttgt tgttattcct tttttcatta gagtatctat agagagtagt atctctctac
    69301 aactattcga tatcgaaatt tctatctgtt tatcatctcg gtaaatagct agagacagtt
    69361 ctctatcttg actctctata gatgcttcaa ttgcattatc gagaataatt ccaagcaccc
    69421 taatacagtc aaatattgga acaggaactt caataatagt acttggacat tcgaatttac
    69481 aacaaatctt attgttattt gcttggtata gcttcgctat caacaaactt ttcaaatatt
    69541 cattttttat attttttaaa taacgatatt caaacttatt ggttagataa gaattagaat
    69601 agatctctaa ttcttttatt tctttttcca atatcgaatc atggttttga ttagcgattt
    69661 cttttaaact cagcaataaa tttttatagt catgtctaaa tctggcaaat ttttcttgat
    69721 ctttttccag tgaatcagta tattttttta gataaaccaa ttcttttctt ttcaattgct
    69781 gttcatattg ttctcgttgc ctaatagtta ttctaataaa taaaaataga acaacaaaca
    69841 tttgaatgat taaaaatatt aagacaccaa acacaaaatg atcaaatact tgatattgat
    69901 gagcaacata agaaacaaat aaaccaattg taagtaaata aatcatgaat atagcagtaa
    69961 gtttagaact ggactgttca acaatcctat ttatagctaa ttttctatat aaccaaataa
    70021 acatcagcaa aaacaaagaa tcaagcatta tctggaatac tacataacca taccctttta
    70081 tcccttcaaa tgaaaacata tacgtcataa ccatggaagt aataatagat ctgaaatcat
    70141 caataagcat acataatagt aatttattta aaagcactat attagttttc ttcttttcct
    70201 ttaatataaa ataacttccg attataggta tagctgcgga aacatcagta aataattcaa
    70261 caaaaaaagt gagtggtatc aataaacata caaaaagata ttttcttttg ttaagatcag
    70321 tattagtcat ataaaataag agaaaaaaga aaaagtttcc cacgaacatt cttaatagat
    70381 aagcttttgt atcgatagta atcaagagat cccctcctga ttttaggata tcataaaaaa
    70441 aattttagtt acacttttta aataatgaaa aaacacattc cactaaattt gatgccggtt
    70501 ttccttgagg ttttgttcca gcacctcctt taattttttt aagctcttga tctgaacatt
    70561 gtttagcatt tagtctattt ttttcttcca ttacgattcc ccctacaaac tataaatact
    70621 tttatgtcac tgattcaata tacctatttt tctaatcaaa aaattttgag acatatttaa
    70681 tattataagt atcattaaaa ttgagattta tctccataat ctgctcgata taaaccattt
    70741 attccagcag ttcttccaat ttcactcaaa tttcttatta attcctcttg atattcagtg
    70801 aatcttattt tattagtata agcagtaaaa tatagataat tcaccaatct atttattaaa
    70861 ggaccgggat ctaattcata tttttgtttt tctaatttta aatatacctt ttgtaaaacc
    70921 tcaagaatat cagaatattt aggatcttta cttatagata tatcattata taattcatga
    70981 acaatttgct tagcattttt tttcatttta gcacttccct ggaattgctc cacctaaaaa
    71041 accacctata gacattcctg caatacaagt agttgccttg gcccaatcga ccgtacattt
    71101 atttttagtg caatacactc catttccata atattttcca ctatgagtgg tacccccata
    71161 gataagttgt gtctctttaa tagacaaaat ttttaaatgt ttcataatct aatcacccct
    71221 aaattaatgt ttttagacta ttattctaac attcattaaa tttcaaaaaa caattccttc
    71281 ttgaaacgta gcaaaataat tcctgaataa gaatttaatc acttttaagt atataaacta
    71341 tgtatattct ttaatatttt ttgagaatgc acttcgtaca taataaactt taatcacatt
    71401 agtctttcat acctacgatc gatctctttg actcgcaccc ataaattcat aatagtttgt
    71461 cggcgtcttt ggacgtttcg aagatgagct acgcattctc tttttttata gacaaaaaag
    71521 atagagacga acatggagct tccaaatttg gatatttgat ccaattttgg aagctccatt
    71581 tatttcgtgt ctgtcttttt attttttcca gctttcgact aattcttggt tctctttgat
    71641 ccagtctttt gctgcttgct gtggatcttt tccattgttg atttccaaca taactttttc
    71701 catatctttt tctgaccaat ggaaattgtc taatactttg taagcttctg gctggtcttc
    71761 tttcaatcct tttcgaacca tcgtatggat ctgctcttcg cttcccattc cgttttcagg
    71821 atcttctaag tatttcagat catatttggc aaacatccaa tgaggtgtcc atcctgtaac
    71881 tacaattggt tcgtgttttt tgatcgcttg acctagtgca acggtcattg ctcctgaaga
    71941 agatgtctct actttccagt ctttcaagtt gtcatatttt tggatcgtgt tttcagcagc
    72001 cgtaactaca ccagctcctg gctcgattcc tatgattttc ttacctgcct gatcggttaa
    72061 ctcatcgatc gaatttacat ccatgtaggc tggcactgct aaaccaactt ttgctcctgt
    72121 caaattggca cctaggtctt cgacttgatc tttatattgt gcatattgtg aaccatgagt
    72181 tttaggtagc caagctgaaa ccatggcatc tgactcgcca tttgaaacag atttccacat
    72241 gattgaatta tctaatggcg tcatcgttac atcatagccc atttgtttca atacttcacc
    72301 gactacattt gttgaagcaa cttctgtatc ccattcaaca taagataagt tgatacgttt
    72361 tgtttctttg gcagatgaaa aactccctat accaatcgca cctaagatca ctactactac
    72421 agcaccaatg atcagtcctt gacgtttttt acttttctgt gttgttgctc ctgcagcttt
    72481 tttattgttt ggctggttca aatgctgtgt aaaacggtca atgatgattg ctaagataac
    72541 taatgcaacc ccgttgacaa atccattccc gacttgtgct ctttgcaatg ctgataatac
    72601 gccgcgtcct aagccgggtg caccgatcat agaggcaata acgaccattg aaagtgacag
    72661 cattgttgtt tgattgatcc ctgccatgat cgtactttta gctaaaggca attctagttt
    72721 gaatagtttt tgacgacttg tgctcccgaa tgaatcagaa gcttctacta attctttagg
    72781 aacttgtcga atccctaaat tcgtaaaacg aacggttggt ggcagagcaa agatgactga
    72841 ggcaaatacc cctggaacca tcccgatacc gaaaaatgca actgctggaa tcaaataaac
    72901 gaatcctggc attgtctgca taaagtcaag gatcggtttg ataatacttt gggctttact
    72961 gctttttgcc atcaagatcc ctaatggtac cccaatgatg atcgagatca cactagataa
    73021 aagaacaagt gtgacagtat tcatcaaatc attccataga ccttggttat aaataaacca
    73081 tagaccgatt aatgtgaaca acgtaagtcc tggacgtttc ttagaaataa agaaagctgc
    73141 taccgtcaat aacaagataa acaaaggagc tggaatcact aacagtaaat ttgtaatccc
    73201 cgacatcact gcctgtccaa tcgtttgtaa aaatgaaaat aggccagaaa aagttgtcgt
    73261 aaaccattct gtgatatttt ctacccagtt tgccactggt aattgatagt tcaatagatt
    73321 attcatgttc actcacctcg cttgtttctg ctaatgcttc aatcacacta cctcggatga
    73381 cgacaccttt taattttcca tcctctacaa ctgcaagtgg agtcggtgag tcataaataa
    73441 tattgaaaat atcacttacc accatgtctt tcccaatcac cgtcacattt tcatctagga
    73501 agtcgatcaa tggacgtttt tgcttcctag cttctaacgc ttgatctgca gtgatgatcc
    73561 ctttcaggtg tctctttctg tcaacagcca tcagcatgct gacttcttca ttacgcatcc
    73621 ttgtcaatgc aacgtttggt ccatcagatt cgatattcgt cgtcaatgca ggtaccatga
    73681 tgttttgagc cgtaagcact ttggaacgat cgacttcttc cacaaattca cgtacataat
    73741 catttgctgg attggtcaat atttcttcac ctgttccgat ctgcatgatt tcgccgtctt
    73801 tcatcaaggc gattctgtcc ccaatccgta aagcttcatt caaatcatgg gtaatgaaaa
    73861 taatcgtttt ttgaacattg gcttgcaggt ccagtaattc gtcttgcatt tctcgccgga
    73921 tcagcggatc aagagccgag aacgcttcgt ccatcagcaa gatctcagga tcatttgcta
    73981 aagctctggc taggccaacc cgttgttgca tcccaccaga taactgacta ggatattggt
    74041 ctttaaatga aagcaaacta gaattttcta atgctttttc tgctttttct tgtcgttctt
    74101 ctttaggtac accacggact tctaacccgt attctgtatt ttccaagatc gttcgatgtg
    74161 gaaacagacc gaagttttgg aaaaccatat tgattttatg acgacggact tctcgcaatt
    74221 cttctttgct taacttcgat acatcttctc catcaatata gatactgccc gaagttggct
    74281 caatcagacg attcaataga cggatcaatg tggatttccc actcccggaa agccccatga
    74341 tcacgaagat ttctccttct tttacgtcaa aattcacgtc atacacacca accgttgcac
    74401 cggttttctt taaaatctcc gttttcggct ggtgatcatt catcatatct aaagcggctt
    74461 gtgtcttttt accaaatatc tttgttaaat gttttacttc tacttttacc aaacaaattc
    74521 tcctttttta tgtaaattca tttttctttc tgaaaaaagt gaccacacta tgttaacatc
    74581 atgtagtcac tttgtcaaaa atgaaagaaa tttgcttgtc caaactgaaa aaaacttggc
    74641 taaatctttg taaataaaag gtttagccaa gttaatattt ttttaatatt tcacacaatc
    74701 attctgcaag ctgatgctcc gggtaaaaaa agtttgtcat acgctgtagt gtatattcat
    74761 ttccaataaa atgaacgatg tcccctgccg taaatttagc ataggggcca ggtgaaacaa
    74821 gcagttcttc attatgagaa attgcgataa ctgtggcgcc agtcgcctgc cagatattca
    74881 actcgctaat tgaacggtcc agatgcattg ctttttctga taaagataat tcaaacggaa
    74941 gtaaaggatt catcttatgt attcgcttcg tttgattgac cagctgatcc aataattgag
    75001 aaaaatgatt cagctcatct tgttgcttct ccacacttgc catgatttct gcttttgtat
    75061 cttggatgga ttgtacatct tgatattgca ataggaaatc ttttgctttt tccttcgaag
    75121 caacaaatgc cccacttcca tgccgtactt ccatgattcc aagatctacc agcacattga
    75181 tagccttgcg ggtagtctca ggagaagcat tgtacgtact ggcaagtgtt gagcgggcat
    75241 ggatcttctc acccacttta tatcggtttt caacgatacg ttcggctaaa tcaacagcaa
    75301 tctgctggta gcgcgggcgg acgatttttt tctttccaga cattttcttt cctctttctt
    75361 tttttacttt ccctcatctt actatgctct agcaaaataa gcaaaaaagg ggagaatagc
    75421 ctcttgcaac gactgatcat cgcttgatct gttccttttt tactgggcaa gctgtttgac
    75481 agtcatcaca attcttaccg gattttaaac gagtatagac aattgcgcct gcacttccaa
    75541 agattaacac acttaataag aatgtcgcca tcctattcct ctccttctaa tgacaatata
    75601 gtataaaact ggttcttgga ttttggctga cggaacaaaa cataaacgag tcctatcatc
    75661 agtaaaatag caagatacgt ccctaacgct acctgtccac cctccaataa gtgtcccaac
    75721 tgataaatca caaaactaac taaataagct aaaccgcatt gatagcctat ggcgatccaa
    75781 gtccatttct tggcattcat ttcccgatgg atagccccaa ttgccgcaaa acaaggcgca
    75841 caaagtaaat tgaaggctaa caatgaataa gctgctgcgg gagtatatgt gtgttgtagc
    75901 acttgccaga tttctctgcc attttcggat acttccgcat gaccaaacaa aataccaaat
    75961 gtgccaataa tattttcttt agcgaccaat cctgtaatcg ctgcgactgt tccttgccag
    76021 tttccccaac caagcggctg aaaaacaact gccaggattc gcccgaaaaa ggctaagata
    76081 ctttggtctt cagaaacagg ttgagcataa aaattataag aagagctgaa ccagatcacg
    76141 atactagaaa caaagataat cgttcctgct tttttaacaa aagacttgct gcggtcatag
    76201 gtttgtctta ggaccgctga ccattgagga aaatgatatg cgggcaattc catgataaaa
    76261 ggagctgtat ctccagcaaa caaacgtgtt tttttcaagc tgattccaga gaaaataatt
    76321 gcagtcatac caagaaaata ggcagaagga gctacccaag attgatgagg aaaaaaggcc
    76381 cctgctacta aggcaataat cggcaacttt gcagaacaag gcatgaaggt tgtgaccatg
    76441 atcgtcaaac gacgatcttg ctcgttttca atcgtgcgac tggccatgac gcctggcact
    76501 ccacatcctg tagcaatcag cataggaatg aaggattttc ctgaaagacc gaatttcctg
    76561 aaaagtcgat ccatgacaaa agcgatcctc gccatatatc cgcagtcttc cagaaagctc
    76621 aagcataaaa acaatataat caattgcggt agaaatccta acactgctcc cacgcctgcg
    76681 atgatgccgt tcaagatcag ctcctgcatc catcccgcta cttgccattc agctaacaat
    76741 ctgccaacat gttctggtaa ccatgtacca aacaatgtgt cattgatcca atctgtcccc
    76801 attgttccta ctgtttgaat agccagataa tagatcagcc acatcacaaa tgcgaagatc
    76861 ggcaaggcta accaacgatt cgttgcaatc tgatcgattt tgtcactcat cgataattgg
    76921 aaagaatcat ttgacacaac acagagtgta catagttggg taataaattc ataacgttca
    76981 ttgaccagaa tcgtctcact atcgtcgtcc aatagtttct ctgttaactg gatcagttgc
    77041 tcgatctctt tttgctgaga aactgctatc tcgtaatcct ctcttacctt ctgatctcgt
    77101 tcaaaatatt tcattgcata ccagcgtttc ttgccgcttt gttctcctag tacatcttca
    77161 atttcatgta aagctgcttc taaacgtgga tcatatgtac agggaacagg aatagaaggc
    77221 cgcttttttg cagactcctg aatcttttcg attagttttt cgattccttg ctttttcaat
    77281 acgctgattg gtaaaactgg tacaccaaga ccataggaaa gcttttctag attgattttt
    77341 tttccttctt ttttgatgac atccatcata ttcagaccaa tgatcatagg aatgtctaaa
    77401 tccaataact gcgtagttaa ataaagattt cgttctaaat tggtagcatc aataatgttg
    77461 atgatcagtt caggctgttc ctgaaccaaa taatctcttg caatcacttc ttctggtgta
    77521 taaggagaca aagaatagat gccgggtagg tcctgaatat gaatgttcgg attttttttc
    77581 aacgatcctt cttttttttc tactgttacg cccggccaat tccctacata ttgattcgaa
    77641 ccagtcaaga gattgaacaa gctagttttc ccgctgtttg gatttccgac taacgcgata
    77701 ttcattcttt ttcctccctt tgtatcaaga ttagttcggc ctctgacttt cgtaacgtca
    77761 gttcataccc tcgcactgtc agttcgattg gatctcccag aggggctagt tttcggataa
    77821 ctatttttac atttcgcgtc aatcccatat ccattaaccg tcgcttcact gcgccttgtc
    77881 cgtggattgc tacgacgatc ccagtctctc ctgcttttaa ttgatcaaga gaagtccagc
    77941 tttcagagga agcagtcttt ttattgacaa agatttgacc tagtatttcc cgacttactg
    78001 ccactcgatg actttttacc agtaaaatgg cattgttgcc tgataaattg acgacgacga
    78061 ttttacttcc ggcaacgatc ccgatatttt gcaaatggcg ttttgttttt tcttctgttt
    78121 cgattcgttc gacttgataa acgaaattct gctttgcctg cgctaaggtc tgcatattga
    78181 ttcctctctt gtgaaataaa tcatgtatta aaatcattca ttatatgttc taattttctt
    78241 acgtgttacg caaataaatg agaatcattc tcacatagaa tactctcggt aattgagaat
    78301 gtcaattata cttgtgatat tatgagcgaa tctttagtat tgatagataa aaatgagaaa
    78361 aaaatatttc ttcatagttt tccacaattt tttctctatt aaatttgcta ttttcccaca
    78421 cgatacttgt tttcagctct tttttcaaaa acacaaaact tagtattcca cagtttccac
    78481 aacacaatat gtagtgtttg ttgtttgact tttttactaa gagttttata ctatctatta
    78541 tagataataa gaatgtgtta gaggaggcac tcaccatgaa cgtaaaaatc ttttctaaaa
    78601 ataattgtat gcaatgtaag atggtcaaac ggtttttaac agaaaatcaa attgcttttg
    78661 aagaagtcaa tatcgatgaa cagcctgaag cagtagactg gttgaaagca caaggattcc
    78721 aaagtgttcc tgtcattact tctgatgcag aaacagttat cggattccgt cctgatcagt
    78781 tgcgtaaact tgccagctaa catgactaaa agaatcaaaa cgtgatacat ggatttgaag
    78841 ggcttgagac agcaccagtt tttgtcgcaa acttccaaat ccttttttaa agcttaaaaa
    78901 caatgcaatg atttgcaatc aagcatcatc aaatacgaaa tgaaggttgg gcgtacgtat
    78961 gagtcttaaa aatttacaag atgtcagtta tttcaagctg aataatgaaa tcaatcggcc
    79021 agtcaatggt caaatccctt tgaataagga taaagaagct ttagttgcct tttttgagga
    79081 aaatgtcaaa ccaaatacga tgacttttct atctattatg gaaaaaatca attacttgat
    79141 cgatcaagaa tatatagaag cagaattcat tcaattgtat tcaccatcat ttattgaaaa
    79201 gctatatcaa tttttggacg agcaacattt ttctttcaaa tcttttatgg ctgcttacaa
    79261 attttattct caatatgcgt tgaaaaccaa cgacggttcc gcttatctgg aaacttatga
    79321 agatcgagta gccttcaatg cgctttactt tgcgaacggg gatgaagaat tagcacttgc
    79381 tcttgcagac gaaatgatcc atcaacgata tcagccagct acaccttctt tcttgaatgc
    79441 tggacgtaaa cgtcggggcg aattggtgtc ttgtttcttg actcaagtca ctgacgatat
    79501 gaactctatc gggcgctcaa tcaactctgc tttgcaattg tcccgtattg gtggcggcgt
    79561 agggattact ttatcaaatc ttcgtgaagc cggcgctcct atcaaaggat atgagggtgc
    79621 tgcaagtggt gtcgttccag tcatgaaatt attcgaagat agtttcagct attctaatca
    79681 attaggtcag cgtcaaggag ctggcgtggt ttatttgaac gttttccatc cagacattat
    79741 tgctttcctt tcagcaaaaa aagaaaatgc agatgaaaag attcgcgtaa aaactctttc
    79801 tcttggcgtg atcgtacctg ataaatttta tgaattgaca cgtaaaaacg aagatatgta
    79861 tttatttagt ccatatagtg tcgaaaaaga atatggtgtc ccattctctt atgtaaatat
    79921 tacagctgag tatgatcatc tagttgcaaa tccaaacatt cgcaaacaaa aaatcaaagc
    79981 gcgtgatctt gaaaatgaaa tctcaaaatt acaacaagaa tctggctatc cttacgtaat
    80041 caatattgat acagcgaacc gcgagaatcc aatcgatggc aagatcatca tgagtaattt
    80101 atgttcagag attttacaag ttcaaacgcc ttctgtgatt aacggcaaac aggaatatga
    80161 agtattagga acggatatct catgtaactt aggctcgaca aatatcgtga atttgatgca
    80221 aagccctaac tttggtcaat ctgtgcgtac gatgactcgt gcattgacat ttattacaga
    80281 tgcatctgat atcgatgtcg taccaccgat ccaaaacgga aataagctga atcatacgat
    80341 tggattaggt gccatgggct tacacactta tcttgcaaaa gaacaaatgg aatatggctc
    80401 agaggattca ttagacttta caaatattta cttcatgctg ttgaattatt ggacacttgt
    80461 tgaaagcaac aatatcgctc gtgaaagaaa acaagttttc cataattttg aaaaatcagc
    80521 ttatgctgac ggcacttatt tcgaaaaata cgtaactgga gaattccagc caaaatcaga
    80581 aaaagtcaaa gcattgtttg aaggcatttt tatcccaact gctgaagatt ggaatgcttt
    80641 gaaacaagca gtaatgaaag atggactgta tcatcaaaat cgcttggcag tagcaccaaa
    80701 tggctcaatt tcatatatca acgatacgag tgcaagtatt catcctatca ctcgcatgat
    80761 cgaagaacgc caagagaaga aaatcggtaa aatttattac ccagcgcctt atctatccaa
    80821 tgagacgatt ccgtattaca cttctgctta tgatatggac atgcgtaaag taatcgatgt
    80881 ttatgcaatg gcacaacaac acgtcgatca aggcatgagt ttgactttat tcatgcgttc
    80941 tgaaatccca gaaggcattt atgaatggaa gacaacaacg aagcaaacga cacgtgattt
    81001 gaatatttta agacattacg ctttccacaa aggaatcaaa tccatttatt acgtacgtac
    81061 ctttactgat gatgcagaag aaatcggaag caatcaatgt gaaagctgcg tgatctaata
    81121 tcatagatag attcgcttat tcatatttta attaaaggag cattctcatg tcagaaacat
    81181 attatgaagc aataaactgg aatgaaattg aagatatcat tgataaatcc acttgggaga
    81241 agctgacaga gcaattttgg ctagatacac gtatcccact ttcaaatgac ctagatgatt
    81301 ggcgtacatt gtctcaattg gaaaaagata cagtaggaca tgtatttggc ggtttgacac
    81361 tgctagatac tgtccaatct gaaagtggca tggatcagtt gcgtaaagat gtccgcactc
    81421 cccatgaaga agccgttttg aacaatattc aattcatgga atccgttcat gccaaaagtt
    81481 attcttctat ttttagtaca ctgaatacga aaaaagaaat cgaagaaatt tttgactgga
    81541 caaatacgaa tccttatctg caaaaaaaag ctgagcgtat caatgaaatc tacaaacacg
    81601 gtacaccgct agaaaagaaa attgccagcg tctttttaga aacattcttg ttctattcag
    81661 gtttttatac tcctctttat tatttaggaa acaacaaatt ggctaacgta gcagagatca
    81721 tcaaactaat catccgagat gaatctgtac atggaaccta catcggttac aaattccaat
    81781 taggattcaa cgagttacct gaagcagaac aagaaacgtt aaaagactgg atgtacaatc
    81841 ttctttatga gctttacgaa aacgaagaac gttatacaga agaattatac gatccaatcg
    81901 gctggacaga agaagtcaag acattcctac gctataatgc caacaaagca ttgatgaacc
    81961 tagggatgga tccactcttt ccagatactg ccaatgatgt caacccaatc gtaatgaacg
    82021 ggatttcaac aggcacaagc aaccatgact tcttctcaca agtcggaaac ggctatttgt
    82081 taggtcatgt agaagcgatg aaagacgacg attatttgat tggattggaa taaggattta
    82141 ttttaattca aaaatttttc gaaaaataaa aagagtttag cgtacagata ttttaaatgt
    82201 acactgaact cttttttatg cttattcact tgtttcttcc agcacttttg gactgtctaa
    82261 cttttccgaa acatgttcca ttcttctcaa taaatagatt ttccggatat ttaatattat
    82321 cgtcttaatc actgcataga caggtatgca aatcagcatg cctaatattc ctgcgacact
    82381 tcctgctcca atcaatacca agatgatcgt caaaggatgg atattcattg atttcccaaa
    82441 taacaacggc ttgatcaaat ttccatctaa ttgttggatc actaaaatcg acaacgccat
    82501 atacaaagct tgaaatggag agataaacaa accgacaatg attgctggta ccgctccaat
    82561 aaaagggccg acatacggga taatattcgt gattccgcaa atgaccgcaa gcaacaagct
    82621 ataaggctga tcgaatattc tcattgccaa aaagctcatt acaccaataa tcaaagcatc
    82681 taagatcgta ctgctgatat aggcagataa tgtttcgttt aattctttta ccgtttggcg
    82741 taactcttta cgaatcgctt tcggaaagaa gtgagacaac gcatcaataa atttgtgccc
    82801 atccttgaac ataaatagca aaataaatgg aacggtaaat aacaaaataa aaaattgcat
    82861 cataaatgaa atgatttttg agacacttgc agataaactg actaatatga tattgaacaa
    82921 attactaaga gataaatttg ctgatgctaa ttgttcttcc aaattgaaat ttttaaactc
    82981 ttcccgctgc gccaattcat ttaaccattt gcttgtttca tctgcataca ttggcaagct
    83041 ctgggtcaat tgaattgtct gttccattaa ctgaggcact acattcatga cagttaaaac
    83101 aactaaaatg attacgacca aaaacgtcaa taaaaaaccg aacactctcg ggatccgatg
    83161 cttttcgaga aaaacaacga ttggatcgaa catataatag ataaaaccag caacaagcaa
    83221 tggtaaaaaa actgccgaaa gcattttcaa tattggacta aaaatattcg gcatttgtaa
    83281 aataaagtac acgccgatga tcgtgagtac tagctccact gtccagaaaa ataattttga
    83341 ttgtttaaaa cgtgattgca tacatctcct ccaaggtcct ttgatacttc tattctatca
    83401 tttaacaaag agttacgcgc tgagattttc atttgcttaa aaaaaacaaa aaaaataaac
    83461 atattttaat gagtagacga gtacttaaac aaaaacacgg tttggagtag tgacaaaaat
    83521 tatactgcag tccctttttc caaataaacg gtgttcaaaa gcttgcatct tcgtaataag
    83581 cccagccaaa cgaaaaatat aaggaactat ttttatttgg ctgggcttat tacttgatgt
    83641 aggacatcta ttttacaacc tcagatcatt tattgcgcaa tactgactaa atgcaacttt
    83701 gtgatatttt tgtgtacgga caactcctcg atcacatcgg cataagtgag cccttttgga
    83761 agatcaatcg tatagatatt tttgtacact cggtagtcat caacgaattt tacgtcaaaa
    83821 ttcacatctt cgattacgat atttttctct tcaaaataat cggtaagaaa atctttggtt
    83881 tcttttctat ggataaattg gatttctaac tttttagtcg taggtacatg gatcacgcgt
    83941 ttcactactg tgagtgcaat agcaatcccg ataaaactga tgatcgcaat ggaatagtaa
    84001 cccatgccga tggcgatccc taatccagca attgcccata aagaagcggc agtcgtaagt
    84061 cccgtcaccg attgtttcgt gacgatgatc gttcccgcgc ctaagaaacc gacaccactc
    84121 accacttgag caatcagcct tgcttcatct gaacgaatcg ttccagcaag ctgtggatac
    84181 tctaaagcat ctcttaatgc accactagcg atctcaactt ggatcaatgc aatgatacat
    84241 gctcccatac aaactaaaat atgcgtacgc atacctgctg gacgattttt atattgtcgt
    84301 tcaaaaccga ttgctccgcc aaatagcata gcgatcccta aacgtaaaat aatctctgga
    84361 attgtcaata ccatatcatt catctaaaca ccctccagtc caatatatca tgtctgaaag
    84421 gagcagacaa aaaaagtgca atttttacct cttacgaaaa aaggactgtg acaaaatttt
    84481 tgtcatagtc ctttttatga ataaacggtg ttcaatcagc tgaccctcgg tattactcaa
    84541 caaacggcaa aatatgggga gctatttttc ctttgtcttc tctaatactc aggtcaaaac
    84601 gctgatttca caacctcttt agcctactat tgaaaattac aacttacttg ctgcttcttc
    84661 atcgatgatc acaacaacat tgtcgtgatt ttgcaataca cttgctggca aatgattcgt
    84721 tacaggtcct tcaatcatcc ctttgattgc atcagctttg ctttcgccaa atgccatcaa
    84781 gacgatttct ttacttttca taattgaacc gattcccatt gaaacagctt ttgttggtac
    84841 atcttctgct ttatcgaaga atcgtttgtt tgcattgatt gttgattctg ttaagtcaac
    84901 tactgaagtc gttccgtcaa atgaagcacc aggttcattg aaaccgatat gtccattttg
    84961 cccgattcct aagatttgga tatcgattgg atgtgcatcg atgatttgat catacttttt
    85021 gcatgctgct tccagatctt ctgcttttcc atctggtaca aacgtttctt tgaatggttt
    85081 tttatcaaat aattggacat ccatgaaatg acggtagctt tgttcatctg aaccgcctag
    85141 tccaacgtac tcatctaagt ttacagaagt catttcactg aaatccaaat cgcttgaagt
    85201 catttcttta tataaagtaa ctggtgtgct tcctgttgcc aatcctaata cttttgcacc
    85261 tttgttcata ccttctttga tgatttcaaa tgcttttttt ccgccttctt cagcgttttt
    85321 tacacgaatg atttccatag tgattgctcc tttatatttt ggtatagccc aattatagca
    85381 ttcttttttt ctttttacaa taattagtat agaccaaatt gcattttttt cattttcttg
    85441 acaataaata ggaatccgtg ttaggtttca taagatggtt caatcaaaca atccatgttg
    85501 catgaaaacc aagcaagtga ttcactgtgg acgctttatg tctgcagttt ttttatgaaa
    85561 aaggagttat tatgagtata ctgacattaa acaacattac ccagcaattt ggcgacaaaa
    85621 tcctctatga aggtgtcgat ctgcaattaa atgctggcga acatcttggg ctgattggac
    85681 aaaacggagc cggtaaaagt acattgatta aaatcatcac tggtgagatc ttaccagatg
    85741 acggacagat ccattggcaa aaaaatattc acaaaggtta cctcgatcaa tatgtggaag
    85801 tcgatgaaac attaacaatc gaagaatttc taaaaactgc gtacgcaaaa gaatacgaaa
    85861 aggaagaaaa aattgctttt ctttaccaaa catatagcga gaccttcgat gattccttgc
    85921 tggaaaaagc tgggaaactc caaacggaat tagaccaagg agtgttttat caaatcgaca
    85981 ccttagttgc tgagatgagc agcgggttgg ggatcgatgt cttaggttta gattcactgt
    86041 tgaaaaatct aagtggtgga caacgttcaa aggtgatttt agcaaaacta cttttagaaa
    86101 acccagatgt tctgatctta gatgaaccaa ccaatcactt agatgatcag catatccaat
    86161 ggctgacgca gtttcttcag gattttgacg gtgcgtatat cgtgatttcc catgaccaag
    86221 aatttcttga tcagatcacc acccatatcg cagacatcga gtttggaaag attactaagt
    86281 atactggcca tctaaaacaa gcattgaaac aaaaggaaca aaatcgcgaa agctatttgc
    86341 gccaatatca tgctcaacaa aaacaaatcg aaaagaccga agcttatatt cgaaaataca
    86401 aagccggttc ccgatcaacg atggcaaaaa gccgacaaaa acaattagat aaaatcgaac
    86461 ggctgacgcc tccagcttca gcaagtaaag ctgtctttga ttttccattc tcgcctattg
    86521 tcacgacatt agcagtggaa acaactgatt tagtcatcgg atatgatcga ccgctacttg
    86581 cacccatcaa tttgaccatc cgctttggtg aaaatattgc cattcgaggc ttcaacggga
    86641 ttggaaaatc tactttatta aaaacactga tcggtgagat tgaaaaaata agtggcgatt
    86701 tccacttccc agataacaca aaaatcaatt acttttcaca agatctgtac tgggaaaatc
    86761 cattagaaac accactacaa tatttaagca gtcaatttcc aaaagcgact atcaaagaat
    86821 tacgtcgcca actagctaaa gcagggttag ttaatcaatt agcaagtgaa cctctcacta
    86881 cattaagtgg tggggaacaa actaaggtga aacttgcaca gttgacaatg aaccaaggta
    86941 atttactgat tctcgatgaa ccgacgaacc atatcgatca agaaacgaaa gaaagcttac
    87001 aagacgggat acagaaattt ccaggaacag taatcatcgt ctctcatgaa caagaatttt
    87061 atcaagatct tgtgcaacga gtcattgaga ttgaaccaaa ataaacgttt gattgaatag
    87121 ttgaaaaaaa ggagctgtga caaaagtttt gtcacaactc cttcttctga ataaatggtg
    87181 gccaattagc tgaccttcgg tattagctca aaaaacggca aaatatgagg agctattttt
    87241 atttggctat tcttattact tgatgcagaa cagcttttca caacctcttt tcgtctattt
    87301 tttattttcg agatttctct ttcctttaaa aacaactgtt tgaaagaaga acgcacatcc
    87361 ttgaaaaaca agcccgctaa ccgttacacc taaccagcca tactgctgcc acattgtcgt
    87421 ccctagcaat gaaccagccg cacctccaat aaagtacata aacataaata cagtattatt
    87481 tcggttgctt gctgcttcac ctagcccttg tactcgtgtt tgattggcga cttgaccaaa
    87541 ttgattcccg acgtctaata aaataatagc taaaagcaaa atggccaaat ggcttccgcc
    87601 aaccaataaa gcaataaagc ttattgtttg cataacaagt cccatataca cgatttttct
    87661 ttcagaataa gaatctgcca gtcgtcccac gataggtgca gcaactgctc cagacaaacc
    87721 aaaaatcgct aatatccctg cttcgaatgt tccccaattg taggcgggac tgctgatata
    87781 aaaaatcaac gtagaccaaa agatcgaaaa tgttccaaac atgaaaaatc cactgactgc
    87841 cgcttctctt aatagacgtt gagaagcaac taaatgcggc aaacttttaa gtgaatcaag
    87901 gtatgaaaca gctgtactac tttgctggac agaacgcggc attttccagt aaagcagaag
    87961 tgtaagaatt ccgactgcac ataaagcaaa taaatagatc atccgccaag aaaaaagact
    88021 ggcaacaata ccagataccg tccgagaaag caaaatcccc acgagtaaac cgctaagcaa
    88081 tgtacccatg accttccctc ttgcttttgg tcccgctagt accgcaccgt aaggaatgat
    88141 gatttgcggc acgatcgaaa gtaatcctat taaaaaagaa gcgcatgcaa ataacgtaaa
    88201 cgaaggcgca aaaaaagcgg ccaacagaga gacggcagat aacgctgcca ttcgaatgat
    88261 caattttgga cgatccacca cgtcccctaa aggaactaaa aacagtaacc ctaacgcata
    88321 gcctaattgg gtcaacatcg tcaatatccc gactgcactt gtgctaacag ataaactagc
    88381 tgctactttt gttccaatcg gctggatgta atacatattg gcaacaacaa cgccacaagt
    88441 gattgataat agtaaaataa gcgaagttgt taaaggtttt ttttcattac tcttcattga
    88501 tttcccccat ttcctatctt agtttacaac ttatggaaaa gattggaaat agaaaaatac
    88561 aactattcgc cacacttatt atttgtgctt ttgttttcct tgttttttct tgcgatcttt
    88621 ataaatgaag acaactaacc ctactagcac agtaacactt gcaaccaacg tgactgcagt
    88681 tttgttatat ccgtgaaaca gagcttctcc accacacgca tacaacacag acgaagggat
    88741 gactccaatc acgatcgaca atatgatttg ctgtagaggc aatttcatcg catctgcagc
    88801 aaaattgacc atagaagatg gaataaccgg tatcatatag cctaacatta cacctatttt
    88861 tggatgtttc atttgtcgga ttgcttgcac ccaatgattc gtttcggttt tcttatctaa
    88921 aaattttaag cgatgcataa ggaaaattgc agtgatgtta ccaagagcat tacccaaaat
    88981 gttgatgatc gcacctgtca gtggtccaaa gctcaaacca gcaatgactc caactactga
    89041 agtaggaata cctggaacag cacacatcac cgctgtcaat acgatcaaga gtatcgatgc
    89101 aaaagtccca tgcgaacgaa tatgtgcgag tagctctgcc ttactcgctc tcggatttaa
    89161 aaataattgg atgtctgtct gatattctaa atacaaccga tagcccacta ccagtatcag
    89221 aatgattccc aacgagatca atatcaatcg gattattttc tttttcatat ttcctcctga
    89281 aaaaaatcta tattcattaa ataatagttt aacataaaaa caaaaaagca ccgaaatcca
    89341 acataggatc tcagtgcttt taaatagtaa aaattattta acagttacag atgcgccaac
    89401 ttcttcaagt ttagctttca attcttcagc ttcttcttta gatacgcctt ctttaactgg
    89461 tgcaggagcg ccatcaacta cagctttagc ttctttcaag cctaaaccag ttgcttcacg
    89521 aactgctttg ataactttaa ctttttggtc tccagctgca gttaattcta cagtgaattc
    89581 tgtttgttct tcagcagcag cagcgccacc agcagcagct acagctacag gagcagcagc
    89641 agatacgcca aattcttctt caatagcttt aactaggtcg ttaagttcta ggatagttgc
    89701 ttcttttaac tcagcaacga tgttttcaat gttcaatgcc attataattt cctccgttta
    89761 attgttcttt tttatttaat gctttatgcg gcaattaagc tgcatctcca tcttctttgt
    89821 ctgccactgc tttgacagcg taagccacgt tgcggactgg cgcttgtagt acagatagca
    89881 acatagatag aagtccttcg cgatttggca attttgccaa tgctgtgatt tcttccaatg
    89941 aagagacttt accttcgatg ataccgcctt tgatttctaa tgcttttgct tctttagcaa
    90001 attcgtccat gattttcgct ggtgcgacta catcttcgtt actgaatgca acagctgtag
    90061 gtccagtgaa tacttcgtcc atgccttcaa ggccagcttt tttagctgca cgtgaaagaa
    90121 tagaattttt gataactttc atttctacgt tagcatcacg aagttgttta cgtaaacgtg
    90181 ttacttcatc aactgttaat ccgcggtagt caacgactac tactgatgca gctgctgtaa
    90241 atttttcgct tacttcatca acgattgctg ctttttttgc gataattgct tcactcattt
    90301 ttgagtttca cctcctgaat tttgatggaa gagttttttg cactgaaaag gcaagtcact
    90361 tttatagtta ctttgctcaa ccagtattat tcatcaccta ttcacttcgt tcatagtgat
    90421 tctactcgct ttgctcgaaa ggaaactcct ttcgctttgc tcaaccagta ttgttcatca
    90481 tctcttcact tcgttcatag tgattcacaa taaaaaactc tatgccaccg cagacataga
    90541 gggactattg aatatattca ataaacgtcc tcggtaggaa attaaggctt gatgccacct
    90601 actgtcttcg gtacaagtta attattaacc tcaactagct tagcatgcta aactagttga
    90661 gtcaagaatt atttttcagt tggatcaatc aacattctaa tatttaatta gaaagaagct
    90721 tggtcaacat ggataccagg tccaaatgtt gttgtgatcg ttacattttt catgtattga
    90781 cctttagctg ctgatggttt agcttttagc aatacatcat ggattgctgc aaagttttca
    90841 actaattttt catcgtcaaa tgaaactttt ccgattggta catggatatt tccagctttg
    90901 tccacacggt aagttacttt accagctttc acttcgttta ctgcttttgt tacgtccatt
    90961 gtaactgtac cagttttagg gtttggcatt aagccttttg gtcctaatac tcgtcctaga
    91021 cgacctacag tagccatcat atcaggtgtt gcaacaacta catcaaagtc aaaccatccg
    91081 ttttggattt tttgaaccat gtcgtcgtca cctacgaaat ctgcaccagc tgcttcagct
    91141 tcttttgctt tgtctccttt agcaaaaact aaaacagttt gtgttttacc agttccgttt
    91201 ggtaatacaa cagcaccacg gatttgttgg tctgcttttt tagggtctac gttcaaacgg
    91261 tatgcaactt caactgttgc atcaaatttt gcaatgtttg tttcttttgc taaagctact
    91321 gcttcggcaa caggataaac tttacttgaa tcaacttttt ttaatgcatc ttgcattttt
    91381 ttgctctttt tagccatttt ggttcctcct tgattgtggt tataacggtt gtacctccca
    91441 cgtgttctat atctttcaat atagagccaa ctgagaagct gctgtcttag ggtgtataga
    91501 ttattctaca gtgatcccca tgcttcgtgc agttccttca accatgcgca ttgctgcttc
    91561 aacgttagct gcgtttaggt cttccatttt taattcagcg atttctctta cttgatcgct
    91621 agaaactttc gcaactttat ttttgtttgg ttcgcctgaa cctttttcga ttttagctgc
    91681 ttttttcaat agaacagcag ctggcggtgt ttttgtaacg aatgtgaatg aacggtcttc
    91741 gtatacagaa ataacaaccg gaatgatcaa acctgcttga tcagctgtac gagcgttgaa
    91801 ttcttttgtg aatcccatga tattgatacc cgcttgacct agtgcaggac ctactggtgg
    91861 agctggagtt gctttacctg caggaatttg caatttaacg attttttcta ctttctttgc
    91921 cacgagacat acctccttaa gtccgtgatg tggttaattg gagatgcata tttctcctcc
    91981 cacgttttat ctgatctgaa aaaatccaga caaataatgt gcaaaacaat gcacactggt
    92041 acagtatagc aaatttattt gttttttcaa gatttttttc tgctattttt acattttgct
    92101 tgaataaacg ctaaatttat tctaaaaaaa caacaatttt tcgttctcat ttcttctttt
    92161 atgttacact tgcgctagca tggttcaaca gatgaaagca aacaataaca cggtttttta
    92221 gacccttgta caaagattcc tacataacaa aatgaggtgg agaaaatgaa agatttaagg
    92281 tatagaagtg tctttgatat tattggacct gtgatgattg gtccaagtag ctctcacact
    92341 gccggagctg ctagaatcgg gaaaatcata cgtagtatat ttggcgaaca gcctgattct
    92401 gtagatattt atctatatga atcatttgca aaaacctatc gggggcacgg aacagatatt
    92461 gcattagttg gcggcctgtt agggatggaa cccgatgatg aacgtttagc tgattctttg
    92521 aaattggcat atgaagccgg tatggaagtc ttgtttgttc ctaagagtga aaaagccgaa
    92581 catccaaact ctgtaaagat gcttctaaaa aaaggaacac gaaagctttc agtcactggc
    92641 atttcgatcg gcggtggcaa tatccagatt tctgaattga atggattcaa aatttcttta
    92701 agcatgggta ctcctacctt gatcgttgtc caccaagatg ttccaggtat gattgctaaa
    92761 gtgactagta tactttctga gaccaatacg aatatcggca ctatgacagt gacacgggaa
    92821 tcaaaaggtg aaaatgccat tatgataatt gaagtagatg atcctcaagt agaagaaacg
    92881 gtaaaaagac tcaaacagct gccaaatatc gacagcgtaa attatttcga ttaaggagct
    92941 aaaaaaatgt ttttatcgat tgaagaatta gtagatcaag caaaagctta tccaagtgta
    93001 gcagaattga tgattgcagt tgaaatggaa atgagtggcc gttcccgtag tcacatcatc
    93061 gagatcatgg aaaaaaacct ctcagtaatg gaacaatcaa tcaacgaggg aaaagaaggt
    93121 gttacctccg tcacaggaat taccggtggt gatgcaaaaa aattagatga ttatttaaat
    93181 gaggcagact ttttaagtgg agaaacaatc ttaaaagctg tacgcaatgc tgtagctgtt
    93241 aatgaagtca atgcaaaaat ggggttgatt tgtgctacac cgactgccgg aagcgcgggt
    93301 gttgttcctg gtgtgctgat ggctgtccga gatcggcttg atttgacaca tgaacagcaa
    93361 ttggaattct tatttaccgc tggcgctttc gggttagtca tcgcaaacaa cgcttctatc
    93421 agtggtgcag aagggggatg tcaagcagaa gttggttctg caagtgcaat ggcagcagca
    93481 gctttggttt gtgcaaaaaa tgggactcct catcaagcag cacaagcagt agccattaca
    93541 ttgaaaaata tgatgggact gatttgcgat cccgttgcag gcttagttga agtcccgtgt
    93601 gtcaaacgta atgctttagg ctcttctcaa gcttttatct ctgctgatat ggcattagcg
    93661 ggtatcgaaa gtgtcattcc gccggatgaa gtcgttgctg caatgtacca agtcggacgt
    93721 caaatgccgt cgattttcaa agaaacagca gaaggtggct tagctgttac gccaactgct
    93781 aaacgacttg cggaagagat tttaaataag agggcgtgat aaagctcctt aatttcgagt
    93841 attaagagat tagttatctt cataacaaaa aacgaagaga ggactaattg cccttctctt
    93901 cgttttttat taatccatca atttcgtatt ttttacttca tcgatcgttt ttgttcctgc
    93961 aagttgcatc gtgatcgaca attctttgtt caggtgttca aaaacagatg ttactccttc
    94021 tgccccacct agattcaacc cataaatcac tggtcggcca atcgcaacta agtcagcacc
    94081 acttgccaga gctttgaaga catgctctcc tcgacggaca ccagagtcga aaatcactgg
    94141 tacacgtttg ttgactactt cggcaatttt tggcaatact tcaaaggacg caggacctcc
    94201 atctagttga cgtccaccat gattggatac ccagatacca tctgcccctg cagagatagc
    94261 gattactgca tcttctggcg attgtattcc ttttacgata actggaagat gggtgatttc
    94321 tttgattgtt ttgatgtcat ctggtgtcaa gccttgtttt gcagctgcat aaatttctgc
    94381 gattcctttt ccttcgccat taccacttgc actttgttcg ctatacgcag ctaagttagg
    94441 cattggtaat ggaaattgga attgattgat gacgtcttct tcacggtaac caccgagcgt
    94501 tgaatctgcc gttaaaatga tagctttagc ccctgcttct actgctttgt tcaaaatgaa
    94561 ctcattgaat ctgtcgtctt tactcatata taattggaaa aactgcggtg cgcctggcgc
    94621 tgcatcggct gcgtctttga ttgtcgtatt tgcataagtg ctgatggaaa agattgatcc
    94681 agcagcagct actcctttag ctgtatcagc ttcccctttt tcatgtgcca atccttgggc
    94741 cgctgatggc gcttggataa tcggtgtatc taattcaatt ccgaaaacag atgtatgcaa
    94801 atcggctgag tcgattccgc gtaatatccg tggcatgatt ttctttgtat taaaagaagt
    94861 cgtattttct ttcatcgtcc actcatcttc agaaccaccg cgaatatagc caaaagctcc
    94921 tgcttccatg cgctctttta cacgaccttc tagttaggca atgtttacaa tatcgattgg
    94981 atgttcttca ttacttgtat gataagtcat agtagatcct tctttcatct tcttgattac
    95041 atataaatca tactaaactt acaaaaagta agcaaacatt tactctcaga tacttttatc
    95101 gctattcttt ccaaataaat cgacttacaa gctgatctac ttcttggttt tcatgaagca
    95161 tactatgaga ggcattttca cctgtcacta ctttttcctc tatttcattt ccgcgttgct
    95221 tcaacaacgc atagaccgct aatgcactgt ttaacggtac tgttccatca ctcaagtctg
    95281 tttcatctag ttgaccagca atcaagaaaa atcgagtggt tataggaata ttaccgatca
    95341 tttgctggta atcttgatag cggttagaaa cgacagcagg cccctttgct aactcatctg
    95401 tcagagactg cgcactatca tcgacaaaat cattaaaagg cgcgccaatt gctgttaatg
    95461 tctgaacttg tggcaatgac gtatcctgtc catacgttcc taaatagcgt agtgcactaa
    95521 ctcctcccat ggaatgcccc actatgttga ctttatctat gccgtagttt tctttcagat
    95581 acaaaagaca agttttgatc cattctgctt gattccactc gttattttta ttatcttcaa
    95641 acaatacttg gaccatcgga ttgtctgctt ttccagacaa atctcctgtt gcttgtattt
    95701 gtccatctgt tcctactgtt aaaaccaatt cttttactgc ttgctgattt ttttccaaac
    95761 gccgcaacat ccctttaaag gaattttctg tcccgctgta gccgtggaaa aaaagtgttg
    95821 gaatagtggt tttttctatc actttactgg attctgccgt tttttcttta tcagaaactt
    95881 cagtagtatt tatcttcgtc gtctggcaac cacttaacgc aaacaaactg ataaggacta
    95941 aagctgctgc agttgcacgt ttgcataaat ttttgattgg ttctgtcata cacctcttcc
    96001 tttccatata gaaaaaagaa agacttgaaa ggccaatcat atgatcgaca tttcaagtct
    96061 ctttattaat cgattttatc tacttgatcg aaatcaagtt ctgtactggt ttcacgtcca
    96121 aacatatcga tgttgacttt caatttttct ttttctccgt caacttctgt tacttgtcct
    96181 tctaatccag caaatgcgcc ttcgatgatt ttcacgactt cgccaacttc tacttctaga
    96241 tcattttgtc gcaggctcat accgatagaa cgcaagatat gattgacttc ttctggaagt
    96301 aatggtgctg gtttgcttcc ggctccgtgt gaaccaacga atcctgtcac accaggtgtg
    96361 ttgcggacaa cataccatga agcgtctgtc atgatcattt caacaagtac gtatcctggg
    96421 aatgttttat gaacgatttc tttttctttc ccatttttga cttcagtttc tttttcttca
    96481 ggaacaacga cacggaaaat aaagtcggcc attttcatac tttgcgcacg agattcgata
    96541 tttgctttta ctttgttttc atatcctgaa tatgtatgca agacatacca gtttttttca
    96601 aaagattcca ttgaaggctc ctcatttcat tgtaaaataa aaaaacctca gtacacccga
    96661 agtttttctt tcgcttcatt atagcactaa aagtacgttg tggctagcga gttattttaa
    96721 aatccagcca aataagcttt ggatggctgt atccattacg taaaacatca atccgaaaat
    96781 aatagaagtt tcgatgacta ctaacgtatc tttacggagt tgttttctgc ttggccaagt
    96841 tacttgtttg atttcatctt ttacgctttt tagaaatttc atgagacaac ctcccttgct
    96901 actgtttatt tcgtttcttt atgtaatgta tattgattac aatatttaca aaacttattg
    96961 atttccaaac gttcgccgct ttttccttca ctgactgatt ttgtgtagtt gcgagaccca
    97021 caaacggaac aagcgagtgc tgcttttttc tttgccattt acttctgccc ccttgctgag
    97081 aatcagactt atacttcata acagtatcac gtaacttttt acttgtcaat ttgtgaaata
    97141 aactatctat tgttttggat aaaattatga tatgattaat ttgaaattaa gctaaaatga
    97201 gacaattgga ggtatagcga tgctattaaa aacacttgta tataagaaaa aagatctgac
    97261 aaccgttaca gagactagta cattagaaga agcattaaaa attttagaaa cttccggata
    97321 ccgttgtgtg ccgatcttag attcttcagg taatattttc cgtggaaaca tttacaaaat
    97381 gcatatctat cgtcataaag caaatggcgg tgatatgacg cttcctgtca ctcatctttt
    97441 gaaaaacgct acaaagttca tttacctgga tacttctttc ttcaaagtat tctttacgat
    97501 caaagagctt ccttatattg ctgtccttga cagtgaaaat catttttatg gtattttgac
    97561 acatagtacg ttgcttaata tgctctctca atcttggagc gtagaacaag gaagctatgt
    97621 actgacaatt gcttccacag gaaagcaagg agatttggct gctattgcaa aaatcatttc
    97681 aaaacacagc agcattgcca gctgtattac tcttgatatc gaaaaagacg aatacattcg
    97741 acgtacattg atcacgctac cggctaacac tgaagcgaaa gtatgtgaaa cgatcgtcaa
    97801 ccacttagag aaaaagaatt ataaagtggt agaaattgaa aatttgcaaa accaagaagc
    97861 ataatcaaaa agcgaaaaaa gaaaacagct aatctgcttt cttttttcgc tttttataat
    97921 tagacacgct tttcaaaatc aagcgcgcga tctaaataat acatcaatgg tgctgaaaca
    97981 gccatgacga taaactcact taatgcaagc gtgccatagg ttgtccaaaa tgcttggcca
    98041 cctgttggaa ctaacatata agcaatcagt cccatgctga tggtaaagaa gatcgtgttc
    98101 aatactaaac gcatctttac atttttcact ttgttttgca ataaagctgt caggcctaaa
    98161 gaaagcaatg tttggccgcc accaaaaacc acatccatga taccaaaacc aaagaaggca
    98221 ttatagacga tgaccccgcc taaaactccc caaagcaatt tacggttaaa gacaactaaa
    98281 tgattcaaac tttctgaaat acgaaactgg atcggccctg aggatacagg cgcaactaaa
    98341 atagttaacg ctagataaag agccatgatg atgccattta caacgattac ggataaccgt
    98401 tgtctgcttt tcgttttttg cattttctct cctcttttct cctagttttt ttaacgcggg
    98461 atggttgatg aaccgcggtt atgtgaaaca aacaataatt ataacagact tttcatttat
    98521 ttcaatccgt cttatctgct tttaaaaaag caaaagctta aacaatgtaa acgtttgcta
    98581 aaaatcgtgg gatatggtat aaagtaagtg taaggggtca taagaattcc cagtaaagca
    98641 gacgaagtag gatctgcaag aacagaattg ttgtgaaact taaataaata aaaaaggatg
    98701 tgggaatttg agcaacctct tactagagaa cggtctagca agcagctgaa gatctaagtg
    98761 gacatgccga accttggaac ttctccttac gtaagtaatg gatcatgcgc ttgctaggct
    98821 tttttgtgtt tttcggtctt cggacctttt tcattttcct agacttctgc tataataacc
    98881 aagaattaat tttgtaacag atttttttga aaaaacaagt ttctttcatt caaaaaatag
    98941 aaaaagcttg ctaattattg gttaaccagc aaacaggagt attaaaatat cttgttttat
    99001 tgaatagcag gaggaaatca tgaaattcca ttatcatata ttgatcaatc catcggcagg
    99061 cagcggaaat ggctataaag tagcagaaag aattttaccg gtattaaaaa ataagcatat
    99121 tgactataca cttcattata gtgaatacaa aggacacgat gctgagattg ctgaaacttt
    99181 ggcaaaagaa acattgattc cttggataga agaagaacag aaaacaatcg atactttccc
    99241 ccttttgatc atcgtaggag gtgacggcac cttacatcag gtacttgata ctttctatca
    99301 gatggaagta gaattcccag ttgcttatat tccagcaggt tctggagatg attttgctcg
    99361 aggggcaggc cttccaaaaa atcccaaaaa aggacttcag ctgattttag cagctcaatc
    99421 accagaaaaa gtccacataa tggcttatga agaaaaaata agtgaaaaaa aaggaatagc
    99481 tgttaataat ttcggtatag gattagatgc agctatcgtc catgcgacaa atcattcttc
    99541 cacaaaaaag cgattgaaca aatacaactt aggatcattt tcgtatttat tctctattct
    99601 ccgtgcttta ttcactcaaa aaggatttcc aattctggta gatgcaggag gaaaacaatt
    99661 aagtttttca aacgcatttt tatgtacagc aacgaagcat cctttttttg gcggaggaat
    99721 cgcgattgtt ccaactgctg atgcgtctaa accagtcatt gattttgtcg tggtcgaacg
    99781 aatcaatttc tttaaaatct tgtggctcat tcttttactt atacagaaaa aacaattgaa
    99841 atcgaaatat ttccatcact acacaacaaa cagattacgt atcgtttcaa caacaccgca
    99901 acatggtcaa gaagatggag aagaaatgga aaaacgacct tttgatatca caataaccac
    99961 aactaaacag ttgttttggt gttaataaaa gaggttttgt cagaagctac atctggaaca
   100021 ccgtttattc ggaaaaaagg actgtgacac gacttttgtc acagtccttt ttttactatg
   100081 cagttaattc tttgcccaat tgggttgcca tcgatagttt ctttctttac ccaaaataaa
   100141 ttggatcatt gaaaacaccg cagcaaaagc aactaagaca caaccattga accaaaaaga
   100201 ttctgcaaat gtttgattgt aactgagtgt ttcactgatc aagttattat tttgaacaaa
   100261 ccaatatgtt ggtgtgaatg ccgctatttt gctaaccatt tctggcaagt attctgctgg
   100321 tacaaacacc ccaccgataa agcaactgcc tgtgataaaa atatctttga tcccaccgct
   100381 ggtttctgag ttttttacca atgaagtgat acaagccgaa aagctaatga tcggcaataa
   100441 aaacaagaaa gtatttaaaa tatgatacca taccgttata tcccacgagg tgtggatcac
   100501 taacagaacc attagaagta agaagccact gaacaacagc agcgagtaac taatcaaact
   100561 aaaggttact ttgcgattca agtttcgttt ggtaatgggc gcactctggt ttcgtttact
   100621 gatctctttg cgattaaatg ctagattgat gacgctgaaa ccgctaaaaa tggatagaaa
   100681 caacccataa gacaagaaat taaaggttgt gcccgtcaac agctttttca tccgctgact
   100741 atatcccgca cttagctcaa cttctccagt aaccgagagt gccatttgtg tctgttccat
   100801 agctgcatcg attgttttat cttcttcttg aaacagaatc agtgtttgca aaaaggtgtt
   100861 cacttgctgt gtaacaactg ttttagaaaa ggcatctggg cgactctgta tcttgatcgt
   100921 cggcatcttt cctacttcga cttgttcggt aaagtctgca ggcagatgta agataatgtt
   100981 tacacgatta aaataaagag catcatcgat ttctttttgt gaggttccat ccaatgtaac
   101041 gactgtttcc ttgtcattca aatatttacg aaggccatcg actacaggcg actcttcttc
   101101 actaatcaag gcgattttcg catcttgcag agaggtattt tcaacatcaa tattttgcgc
   101161 aaaaaagaat gtggcaacaa cagtgataat tacacctatc agtaaattcg atttatttgc
   101221 tttaagcaat gtccaaatcg ttttataaag cgtcataacg cacccctctt tccatccaag
   101281 catttcctaa cgcaaaaagg aaaataaatc cgatcaacca tagaagattg gtataaaaac
   101341 tagccaaatc agtgtagaaa taaagtttat acaaactttc gctgatcaag ttgacgagat
   101401 ttaattgacc aacaatcgga atatgaagat caatccaata cttcacttgt tccgacccca
   101461 tcataccagc aaaaaagctc atcgcaatcg tcactgaaat caagatgcta tccttttgca
   101521 ccagattcat ttttggtatc aaattaccaa ccaatgtacc taacaaaatc gcacacaacg
   101581 accccagagc ggtaacaatc atcaaccatt gccaacgttc accaaagtct acttgataga
   101641 taaaacgaaa gacagctaac ataatataaa tctctgtcaa aacaatcgta aagcttgctg
   101701 ccaaattagc gattgaaact aacgattgct ttctaggaat caaggacaag cgaataccat
   101761 ttgacgattg atttgcttgc tgatcctgta cattgcggac cccccacatc gtcccgtaga
   101821 gaatcgccat tccaatcaga gtgaagaaat aaaaactttt gaaactcata ttacgacctg
   101881 catgaacttc ttgaaaagat acttcttgtt caaaaacagt catgatgggc gcgagatcaa
   101941 cgttctccac ttctgccact ttactcgaaa ttataccaat acgctgtaaa aattgatcca
   102001 tgacgttttt catcaacgtc tgactcattc ctgcttgacc cacatggagc gaaacagatg
   102061 aaccatcaat gagataaaaa ccagccaaat catctgcatt tagcttttca ttcgcttcta
   102121 cttccgatag ttcctgtact tcaaataatg gtttatcatt gacttcgact tgttctaaga
   102181 ctgtggtaaa attttccgaa agcgctgttt gatccgcttt gattacaatt ccagtattaa
   102241 tcgtttcgag attgccacct tgatcaatct cgccaaaggc cgccataaac atcaatccta
   102301 aaagaattgg aaaggccaat gtccaaaaca acatggattt atttcgcagc agtatttttg
   102361 tgcgatattt ataaaaatgc caaaacatta tttcccctcc tctagtctct caaatccttg
   102421 ccagtaatct ctaaaaagac atcattcaag gacgcttctt tggttgctat ttttccgtaa
   102481 ctgatctttt cttcttgtaa gattgtaaga atcggcaaca atactgtatt tagttcagta
   102541 gttgttactt ggagctgacc ttttttataa gcgattccat cagaagctat tgttcgctga
   102601 caacacgttt tctgggagta atgggatgtc gatcgtcaaa cgatccgccg tccgtaccat
   102661 atcttttaga gattctttgg ttcctttagc aatcacctgt ccttgatcca tgatcacgat
   102721 ctggtcgcaa agaatttcta cttcttccat gtaatgtgtt gtatagacaa tggttgctcc
   102781 ttgtcgattc agctccttga tactttctaa aattttattc cgactttggg ggtctacagc
   102841 tactgtcggc tcatctaaaa aaattaaccg cggcttgtgg gcaatcccac atgcgatgtt
   102901 caaccgacgt ttcaagccac cactaagttc tcctggacga aacgaaacat atttttctaa
   102961 tcccactaat tgaatcacct cttcaatcaa ggctttcctt ttctcttttt cggaaacata
   103021 taaaccgcaa aaataatcga tattttcttg cacacttagt tcgtcaaaga ccgcaacgtc
   103081 ttgaggaacg accccaatca ttgccttgac agcataattt tcaggagtca ttgttgtccc
   103141 gaacaattta atggttcctt tgtcataatt taacaaagaa agcatacagt tgatggcagt
   103201 cgatttccca ctgccgtttg gtcctaacag acctaagact tctccttctt gtacttgcag
   103261 atcaaaatga ttcaatgcta caaaatctcc atagcgtttg actaatttat caatttcgat
   103321 aatcatcatg aaaaactcct tccaaatttc ttgttgatct gactataata aagtgcaaga
   103381 aaagaaacta gtgacgattg gctaaaccac acatgacatt tgtcacaatg aaggagtctg
   103441 ctatgcataa atctcggcta ctcaacgaaa ctagctttct actggttatc tcattgcttt
   103501 tgctggtaag tcaaggattc gttgctatgc aagttatcta tttattgatc gccgttttat
   103561 tcactggtgt cagttattta ctgcctacaa agccaaattg gattttccaa gttattctat
   103621 ttcttttatg tgccttttta cctgatcttg tcctgtttct gccagcgacg atgcgagtga
   103681 tcgcccctga agaaagccac cttgattact tgtttttgtt aggttttttg ttgatttcga
   103741 cggttggtaa tcatcccccc atcaaggtcg cctttgtcgt aattttgctg tttttttcct
   103801 tttacttacg aaaaaaagat caacgaacga ccgatcttga gaaaaagtac attgtctcca
   103861 aagatactca ttgggaaaaa caacaagagt tatcggaaca aaataaagca ttggccctgt
   103921 cacaagaaac acaattagcc ttgcaaattg tggaagaacg gaaccgaatt gcccgagaca
   103981 tccatgacaa tgtcggtcat ctgctgtcaa gtgcgatttt acaaattggt gcgcttgaaa
   104041 tgatcaatca agaaccaaaa ctaaaagaac cattagaaaa tttaagtgcc accgttcaca
   104101 ctgggatgga tcggattcgt caaagtgtcc atgacctcca tgagacatcg atctcttttc
   104161 aacactcctt agagtttctg atcgctgatt ttccttcttc tgttacgatt gaaggaaact
   104221 tgtttgaagg attgaatgaa acgcagcaaa actgcttctt aatggtcatc aaagaagcct
   104281 taaccaacag tatcaaacat agtcatgcca aaaccgttgt tttacatttt cgaacgttgc
   104341 cggcctttta tcgcttgcaa atcacgaatg atggcaccag cccacaaaaa aattctgctc
   104401 ccggtattgg tttgaaaacg atgcgtcaac gtgttcaaga acaaaaggga caagtccata
   104461 ttttccaaga aaaccagcaa tttcagttaa cgatcatttt accaagggag ggacaccaat
   104521 gataacagta gtcattattg agatgatcca tttgtgacga aatcgttaca aaccatttta
   104581 gaaagcacga aagagatccg tgtgttaggc attggtcatt gtgccaagga tgcgctagtc
   104641 ttatacgaaa cccatcgtcc cgatgttttg ctgacggaca tccgcatgcc taaacaaacg
   104701 ggcatcgatg ctgccaaaga aattttggct aaatttccca aagccatcct tttgcttttg
   104761 acgacattca aagatgaaga atacatccgc gaagcatttt ccatcggtgt caaagggtat
   104821 ttaatcaaac agaacttgca agcgattatt ccttctgtca aatccgctta taatggacag
   104881 gccgtatttg gtaatgaaat catcgagact ttcactcaaa tgatgaagaa taaaccgacg
   104941 attgatagtc atgcttatgc ttcttttagt gaacgtgagc ttgcaatcat caaagaagta
   105001 gctgccggga aaaacaataa agaaattgca gatgccttgt acttgagtga cggcactgtt
   105061 cgcaattaca tcagccaatt actagaaaag ctagatttac gggatcgcac gcaattggct
   105121 atctattttt atcagcattt gcaataagtc ttatctaaca caaaaaaacc tgaatgatgc
   105181 tccttcgcat cattcaggtt tttttcacat cttctattca attgtcccgc aaaccatttc
   105241 ctcacgattg aaagaatcaa ggattcgcag ggctgccagg attcgttgga ttgttcggcg
   105301 tgttaggcgg aaaaataggc gccttgtcta acgttttttc tagttttgat tcttcacgat
   105361 cgtctcgttc tacatcagga ctttcattca atttgaattc tttttccatc tcatctaact
   105421 ttttaaagtc attgccagat tcttttgcta atttcgctaa tttatcttcg gtttctttag
   105481 ccataaagta acgcccccct tttgatttca gcttagcata tcacactgaa aaaacaaaag
   105541 aaaacgctaa ccaacgatca tttttagcta tttctcatct ttaaaatcaa gcattttttg
   105601 ccggtataaa atcgtaggga gaactgtttt ccataccaat catcggatct actaactggt
   105661 tatcgatcac ttctgctgta agaacgaaat ctttagaaac agcaggttct acctcttctt
   105721 tcttttcttc tccaacaaat gaagaaaaca gatctggttc cactgtttcc attacttggt
   105781 ttttcgtttc attcgtccca ctgtcatctt ctacaggtag cttttctttt acaacccgtg
   105841 gctcttttgt atagttccca tcttcaaatg gatcatttcc gaccaaagaa tcttcataag
   105901 ctgctagttt ggtccggaga gtgatattca ttttatcatt atccatgatc cttgatttca
   105961 acgtagtcat ccggcttgct gattcattcg ctacacaagt gacataggct tgctcttccc
   106021 ctaacaaaat caacagttcc ttactgcgag tcactgccgt gtagagcaaa ttacgctgaa
   106081 gcatccgctg atattgatgg accatgggca aaataaccat cttgaattca ctgccttgtg
   106141 atttatggat tgagcaacaa taagaaagag tgattttatt ccattcgttt cttttataag
   106201 tgacctcatt tgcatcaaac tggataacta attcatccac tttatcttca gaatcttttg
   106261 ccaagatgat acccgtgatt tctcccatat ctccattgaa tacattcaat tcgggagtat
   106321 tgactaattg gaggactttg tctcctatcc gataaacggt gtcgttccaa tgtacttcct
   106381 tttttccagg tttccctgga ttgaatatct cctgcatcat tttatttaac gcatcgatcc
   106441 ctgcaggtcc ccgatacatt ggtgctaata cttggatatc ttgtgcacgg aatcccttat
   106501 ttttcgcttt ttccacaatt ttagagatca agggttcaat ttgataagca tcacttcgga
   106561 aataggaacg atctttttga ttctttgtga aatcttttgg cagacgtcct tctttgatct
   106621 catgggcaag aggaataata ctagaaccat caccttgccg ataaatctga ttgagttcca
   106681 ttttgggaat ttgttcgatt tccaaaagat catggagtac ttgaccagga ccgacagagg
   106741 gaagctgatc tttgtctcct actaagataa cttgcatatt cgtcggaatc gctttgaata
   106801 atgtgttagc cagccatgta tcgaccatag acatctcatc aacaatcaaa agtccgcctt
   106861 ctaattcttt cgtactgact gaaggtgttt tttcccgtcc attcagcccc agaagacgat
   106921 ggatcgtact ggcaggcaga cctgtcgttt cgttcattcg tttagctgct cggccagttg
   106981 gtgctgcaag tagaatagga aaaatttctt gggtatattt tgaaggatcc aattccagtc
   107041 cgttcaactc tgcaaaaaga ttgacgattc cgttgatcac agtagttttc cccgtacctg
   107101 gtcctcctgt taaaataaat agaggggaac ggattgcttc agcgatagct tgttcttgcg
   107161 aaggtccata ctgtatgccg aatatttttt cgatacgccg aatattcttc tgcacttctt
   107221 tttcaggata atggatttct tttttacgac tgagaaggcg ctggatcgaa ttaccgatcc
   107281 cccattcaga aaagtacaaa ctgttttcgt aaagattagt ctcttcttgt tgtatctttc
   107341 cttcttcaac aagttggata attacagtag caacctgatc aggctggatt tcaattgggc
   107401 gacttgtttc taaaatacgg atcgtttgct gaagcaatgt ctccgccggt acgtatgtat
   107461 ctcctgtttg aactgcatgc tgaaaaatct gatgcaagat agctgctcga attcttctcg
   107521 gtgaatctgc tgcaataccg atttgttcgg ctagattatc tgcacgtttg aacccgattc
   107581 cttctatgtc ttcgactagc tggtacggat tttcttcgat gatatccaaa gactcgttct
   107641 tataggcctg gtagatactg aaagctaact gactaccgaa cccgtaacga ttcagtccca
   107701 tgatcacttg atccatcccg tggtttagcc gaatcgtctc agcaagcatt tctctttttg
   107761 gcttcgtcaa accggagatt tgttttaata ccgaaggatc agcaatgatt ttttcgatag
   107821 catcttctcc cagcaattct acaatttttt ctgctgtttt cttcccgatt cctgggaatt
   107881 tttcgctgga aagatacgct acgatcccat ttgcagttgt tggcttttct tgctcatatc
   107941 tttcgagttt aagctgcctt ccgtatttag gatgatccac taattctcca taaaaacgat
   108001 aagtctcatt ttcttgaata tcgccgaaac ttccggtgac tacaatctct ttttcacggt
   108061 aatcagctgt ggtttcactg atgtgtacca aaagcacttt gtaaaaatta ctaggatttt
   108121 gaaaaaaaat cgcggcaact gtaccaacga aataaggcat ttcttctggc tgcatcggaa
   108181 gccgcctcct tcttctatag taaaggttct ggtgctgttt cagttcctaa aaaatctgtt
   108241 tggttccata ctttcagttc atatggcaat aatctgcaag gctcttcagt ctctaaaatc
   108301 gtcaaactac tattgaacaa tccacccatt tcacgcaact cacttagctc ttttcctgtc
   108361 atccattgaa tggctgcagt taaagaagct ccatgtccta cgaataaaag tgggccatct
   108421 ttatgttggg caaccgcatc tgctacaaca gtttcgatac gtgtgattgc cgattcaatc
   108481 gtttctccgt gaaaaggaga aggatcatac agatctaaat gattacgcaa attcggcaga
   108541 ttatccggat atttctggta catttcatcg atcgactgac cttctaaagt acccagccct
   108601 agttctctta gcttatctgt ataaaaaatc tctaccggac gagcaagctc tttgttgata
   108661 ccttctgctg tatcacgtgc tcgctttgct gtactggaat aaattgcttt aaaaggaaca
   108721 tattttacct ttttcccaaa tgctttgatt tcttcgtaac tttgtggcaa aagcggagaa
   108781 tcgccattgc tcccttgaaa acgtctttcc tgattccatt gtgtcttccc atgtcgggta
   108841 aaatatagtt ccatacgcag caaactcctg tctttctttt attttactct ataataaact
   108901 gtctaatcca gcttgtcatt ttcatagtga tgcgtcaatt ctaaattagg gaatccttgc
   108961 tggcgaagtg cttcatacac tatcattgca gctgtattcg ataaattcaa tgagcggaca
   109021 tgctcatcat tcatagggat gcgtaaacac ttttcttcgt tttcacgcat aaatgtttct
   109081 ggcaaaccgg ttgtttcttt tccaaataaa aagaagtgct cttctccatc agcaaaattt
   109141 tcgtcactat atactttatg ggcaaatttt gagatcaaat gtagtttacg attacctaaa
   109201 aatgttaaaa aagcttctaa attactgtgg taagtaatat ttacatcatt ccaataatcc
   109261 aaccctgccc gttttagatg tttgtcatca gttgaaaaac ctagtggctc gattaaatga
   109321 agcggagtat tcgtggctgc acacgtacgg gcaatatttc cagtgtttgc agggattaat
   109381 ggttcaaata aaacgatatg attcatcagg atcattcctc tcatatttat gttcgtttct
   109441 attttctgac aatttgattt ttgcataaaa aaaaacgtat caactcggtg tcagtcactg
   109501 cgagtcgtta cgttagtgaa gctcttctca ctaactttta tcagaacagg aacctgataa
   109561 aaaccaatga aaaaacaact tgttgctaat ataacaccct caactttttt ttgcaacctc
   109621 tactcattaa aaactgctag aaaaacgttt tctcttagtt ccttttaata attctatgtc
   109681 aattgtaatc ttcttcaaag gattcttata taagtctgct ttgattcgct cttctacctg
   109741 ccattctaaa ggtgacatgg ccaaaagatc tttttgattt tcctctggta tctcaaattc
   109801 ataggttaca cgctgacgtt cagttaattt cattgcttca gcaaacttgg ctactacacg
   109861 ttcattggaa taactctgtt tttcaggttg attcggataa aaagcctgac gtagttcctt
   109921 taaataattt tcttgtggca ccaccttcaa cacttctcca tcttctgaga gtacacgttg
   109981 gaattcttgg taatgagaag gcgaaaagat atttaaaacc gcgttgaatg tttgatcagc
   110041 aaacggcaaa ttggtcaaat cagctacaca ccaaaatgct tcggcagatt gttctgtagc
   110101 tgcgtagact ccttcttttg aaatatcaaa tccaacagca ttttgaatct ttttcaattt
   110161 tgaaagttca ttcaagaagc taccttctcc gcagccaaca tctaatagcg agacttcttc
   110221 aggtaaatgc tgcgcaatag tctcaataac gggctgatac atgccagatt ggatcattct
   110281 acgccttgga acgaacattc cttgatcgta ttctgtttta accgcatggg ataaaaaata
   110341 aagtgttcct tttttggaaa ggtcaaaacg gtgattattt ttgcatatca agccattatc
   110401 agactttttt acttcttctt ggcaaaccgg acagcggaac agctgatgat tttctgccaa
   110461 aaactggcgt cctcggtcaa ttttttttaa catagttccc cctcatttct gttttatctt
   110521 accgttagat gctcactttg gcaactgcta aaaatatgat acaatgccta gaagaaagtg
   110581 aaagataaag gagaagatta gatgatcaaa gaattttgcg ctgaaaacta cacatctatt
   110641 cctctagcaa ttgctagagg agccgatcgg atcgaattgt gtgacaactt agcggtcggt
   110701 ggcacaaccc cgagtactgg tgtgatcgaa gaaacgttaa gttatgctgg ggaaaaagat
   110761 atccccgtaa tgacgattat tcgtcctaga gggggcgact tcgtctataa cgatatcgaa
   110821 ttgaaaatca tgcatactga tttgattgaa gcaaagaaat tagggacgga tggcgtagta
   110881 tttggttgtc ttactccttc aggctggcta gacgaagagg ccttagaact attgatcgaa
   110941 acagcagaag ggttgcagat caccttccat atggcttttg acagtattcc tgaagatcgg
   111001 caattcgaag caatcgattg gctggtagaa catggtgttg accgtatctt gactcatggc
   111061 ggtcctgctg acaaaactat tgtagaaaat ttcccacggc ttaaagaatt gattgcctat
   111121 acagatggcc gcttaatcat tttgcctggt ggtggtgtca ctgcagagaa tgcagcacat
   111181 gtagctaaag aattgaacgt aagcgaagta cacggaacca aaatcgtgga tcttcagtta
   111241 taatcttata aacaaaaaaa catttgcaac aggcataatg cttattgcaa atgtttttgt
   111301 ttttttacat aaaatagccc ataaataaag aagcaatatt gaaataaatc agtacactcg
   111361 tcaaatcgct caaagtcgtg ataaagggac cgcttgctac tgctggatca aatcctagac
   111421 gatccattag catcgggatt aaactacctg caagattcgc cactgtgatt gcaaatagca
   111481 tagccatccc tatgacaaac cccaagataa aattatgttt ccaaaaacct acgattagaa
   111541 aaatcgtgat ccccgtaaca gctcctgtga caacgccggt caagacttca gccaaaacaa
   111601 gtcgaacaaa tccatgatct ttctcatcag aaatcgcaag tcgacgaaca gccacagcta
   111661 gcgactgggt tccagcatta ccggcagttc ctgtaatcag cgaaatgaag actgctaaaa
   111721 tactcgcttc acttaccaag tcttcatagt gactgattaa agaagcggtc gacataccta
   111781 aaaacaacag agtgatcagc caaggcaaac gtcgagacgc tgcctttact ggattttcat
   111841 taatttcttc cacattgacc ccggcaagtc ctgaataatc gctagcagct tcatcatcaa
   111901 taacgtcgat gatatcatcg actgtgacga ttcctaacaa atgatcatca taatcggtaa
   111961 caggaagagc taagaagtca taatctctaa atgtttgtgc cacatcttct tggtcgtcgc
   112021 ctacatgaac tgaaagcact cgttcgctca tcagatcaga aatcattgcg tcgtcatcat
   112081 tcacgattag gtcgcgcaga gaaataaccc ctactagctg accttcttga ttaacgacat
   112141 agatgtaata gattgtttca gctacatctg cttcgttctt cagcacgtac atcgcagagc
   112201 gaacagtttg attggctacg atcgaaacaa attcagttgt catgatcgcg ccagccgttt
   112261 catcctcgta atggagaagt tccttgattt cactggcatc gtctgccgac atcaaactta
   112321 aatatttagc aatttgcttt ttatccagcg tattaagcaa gtcaacagca ttatctgtat
   112381 acatctcaga aagcatatca gctgcatagc taggacgcat ttcatctagg tattctttca
   112441 tatgttcgtt gtcttcttca atcacatcga acatatccgc taattcttta ggcgacagat
   112501 aggaatagat cagctgcctg ttctcttctg taagagattg gtagaattgc ccctgctcat
   112561 agatatgcat ctctaaaaaa ctgtttctga atgcctgaat attattttcc cttaaatctt
   112621 gagtcaactg ggcaaatctt tcctctaatt cttgattttc atccaaacca atctcacctc
   112681 gccttattct tcaaaccgtc tcacaactgc ctccatgtct gcggctaaag gctgcttgaa
   112741 ctccagcaac tcttctgtaa atggatggta aaaacgcaga tcataacaat gaagggcttg
   112801 tctttttatt cccagatcca ttcgcccgcc atacatatca tcaccgagca gggcacagcc
   112861 aattgcggaa aaatgaactc ttatttgatg tgtccttcct gtatgcagct ggatatcaac
   112921 taacgcgatt tctgttagtc gcttctctat ccagtactca gtctgtgccg aacgtccttc
   112981 atcagagacc attcgcttca atagcgaaga ataatctcgg gcgatcggca aatcgatatg
   113041 tccatgtgcc gataaatctg aaagccttcc actgactaag gcctgatatt ttttcacaaa
   113101 cttcttttca cgaagttgca tatctaattt tgcgtgcgca aatccatgct ttgcaaaaag
   113161 catcaaacca gatgtatccc gatctagtcg cgtcaccaca tggattactt ggttttcgta
   113221 accttgtttt ttataataag cctttacacg attagccatt gtcccatttg gatggtattg
   113281 ggcaggaata gacgaaacgc ctgctggttt atttactacc agaacgtgtt catcttcata
   113341 cacgatatcg atcggtgttt catccaaaag tacggtttca tgttctcctt cagcaggaat
   113401 cacaatggtt accttatcat ccttagctag agaaaacaag acattttcta cttgatcatt
   113461 aactttgatt tgaccgcctt gaaattttat tttcgctaac agaccctttg agatcccttt
   113521 ttcttttaaa aaatatttta cttgctgaga atgatctttc tcataatccc atgtaaactg
   113581 catatcaatc ctcactaata aaggcatctt tcacacgatg ccaaaaatgc atatgtcgat
   113641 aagaagcaaa atggatccgt tcttctgcta ttcgataata aattgagcgg atatttgctt
   113701 ttgcgacatt caattgatca accgttacaa gataatcttc tgtattttcc aattttattt
   113761 ctagccattc atcatgggca atcacgatcg gagaacccaa agtacgaaac actcgattat
   113821 tcagtgaagc aatctctgcc aactgaaagg cattgatact aggatggatc acagcaccgc
   113881 cgacactttt attatatgct gtcgaaccag taggcgtaga aatcgtcaat ccatctcctc
   113941 taaaactttc aaacagctcg tttttgatgt atacatcggc taccatcgta cgattggccc
   114001 gtttaatcgt tgattcattc agtgctaaaa aatgctggtc cggtgtttca tccaaataac
   114061 tgatccgaac atccagcaag ggataactaa cactttgttc ccggttcgtt cgtaagctgt
   114121 ctactagttc ttccagctcg taatcccgcc aatccgtgta aaaccctaaa tgacctgtat
   114181 gcacgcccaa gaaacgcaca tcattcagac aatgactgta gtgatggaac gccgacaata
   114241 atgtgccgtc tccgccgact gagatgacca attctggctc atgatcatct cgttgaatcc
   114301 ctgcttgttc taaaagtgcg ttcaaacgtt ctgtcacttc tatagtcttt gcttctttat
   114361 tatgaacgat cgctactttc atcccctgcc tcctctcttt cgctttcttt cttcaaaagc
   114421 gttcgatagt agacatcatc tgattttcct cttccatggg agaataaccg ctgtgcttct
   114481 tggatttctt cacggatact ggacatctct tcatccaact gataggcagc ttctgccgca
   114541 cgctgaagtc gttcactcat ttcttctgga aaaacgcctt gatatttata attcagcgaa
   114601 tgctcaatcg ttgcccagaa attcatcgca agagtccgaa tctggatttc cgccaaaatt
   114661 ttcttctcac cgctgatcag ctgtacagga tactcgatca ccagatgata agaacggtag
   114721 ccacttgctt ttttatttgt gatgtaatct cgttcttgga gaactttcat gtcttttctt
   114781 ttacggatga tctcaacaac ttgatggata tcttctacaa actgacacat gatccttaac
   114841 ccggcaatat cagacatttc ttcttctaaa cgtcccattg gaatatgccg taattgtgat
   114901 tttgttacaa tactatcgac tggcttgact ctcccagtga caaattcaat cgggacatgt
   114961 cgattttgtt cacggaactg tttgcggatc ccccgcagtt tcactttcaa ttctgataca
   115021 gtttgttcat atggtgctaa aaatgcttcc caatctcgtt ccatagctga tacctctact
   115081 tcattaacat tcattgttta ttctaccata tatgcaaagt tttttcgtac tcttgattta
   115141 tgcattgacc aaaaaaagaa aattaggcaa aatagacaaa aaggagtcga tcaaatgaca
   115201 caaatgcttg aaatcgaata taaatctatg ctgacaaagc aagagtacga gatattcatc
   115261 gctcactatc aattaacaga taaagatttc cgtgtacaga ctaatattta tttcgatacc
   115321 gttgatgaac agctgaagaa acaaaattgt ggcctacgga tccgtttcgt tggtcatcaa
   115381 gctgaatata cattaaaaac acctgctgaa aaagggcgtc tcgaaacaac ggataccttt
   115441 ataacagaag aagcagaagc atttatcttc gaaaaacgtc tgcctcgttc aggcgcagtt
   115501 tttcaaaaac tttctgattt gaatatcgat cctgcttcat taatccaaac cggaaagctt
   115561 acaacaaaac gggctgaatt ccctattgaa gaaggacttt tagctattga tgaaagctgg
   115621 ggagacaatc tacacgattt tgaactggaa ctagaggtag gggatgcatc tgtgggaaaa
   115681 attgctttta taaatttttt aaaacgtttt tctttacctt atcgtcctgc taagaacaag
   115741 atccaacgta tgcttgaagc taaaaattag aaacctttca ttttcacaag gcacttgagt
   115801 tcattttttt acttttttct gttaagttat aggatgtgaa agaatctagt cactagttgt
   115861 atagaatcta ttttggggga gattcatatg atcgaaatct atttatttgt taatccttta
   115921 ggggaatact gtttcgaaat ggaacaacag ttattacaat ttatcgaaga agagtacggg
   115981 acaccatcaa aagaaaagat gcaatttcgc tttcttcctt tggtcaattt gcagacaatt
   116041 ggggatgtca tgcaacaaaa aggaatttct cagaacaatc ttgaggaacg taatcactta
   116101 ttctcaatga cttattctgc agcattggac tgcaaagcgg cgcagtttca aggaaagaaa
   116161 aaaggccgcc gttttttgat caaattgcaa gaagcagtcg gctgtaatga cataccatat
   116221 tctcaagaac ttgctgaatc catatttgaa gaaatcggcg gcgatttgaa tatgtttaaa
   116281 gaagatcgtc agtctgactt cgttaaagaa gtattctttt ctgatcaaaa aattgctcgg
   116341 gaaatgggca tcacaaaaca cccttctgca gtcgtttaca attatgcctg cgaccgtgat
   116401 tttggtgttt tagtagaagt aaaaggtaca agtagccttt ggagaatcac agagctgtgt
   116461 aaaacaacag ataactcata tcaagttttt aatggtgaac atttacatac aaatgattct
   116521 cagttccatt caagaactag ccatttacac ttgctttcta attaaaaaaa tacgtcgact
   116581 cccttacaag agagccgacg tatttttttc gtttctattc gagaaaatca aaaatagaaa
   116641 gccttataaa cgatcgatca attcttctaa ttcatttaga cgttgttcaa acatcgacat
   116701 tgcatcttca atatatgcag cctgtgtcat atcaactcct gcttttttca ttacttccac
   116761 aggataatcg ctgttacctg cttttaggta agccaagtag ttctctagtg cctctggttc
   116821 ctggtttagt attttcttcg ccagtgctga agcagcagaa aagccagtcg agtattggaa
   116881 aacatagtaa ttataataaa aatgcggtat ccgtgaccat tcgaatttaa tttctgggtc
   116941 ttcttcgact gctggaccat aatattttgc attcaattta ccataactat cacttaggta
   117001 ttcactagtc aatggcacac ctttttcatc ttccgtatgc atgaaatgct cgaattcagc
   117061 gaattgtgtc tggcggaaaa ctgttccttt aaacccatcc aagtaatggt tgagtacata
   117121 agcccgtaca cgagggtctt tttctgtttc caataaatac tccgttagga tattttcatt
   117181 cgttgtcgaa gcaatttctg ctaaaaagat ggagtagtcg ccgtacacat aaggctggtt
   117241 cgaacgagtg aaataactat gaacactatg tcccatttcg tggacaagcg taaatagctg
   117301 atccagcgta tcatgccaat tcaataaaat atatggattt gtgtcatagc ttcccgaaga
   117361 ataagcatcg cttcgtttcc ctttattttc gacaacatcg atccaacgtt cagagaatgc
   117421 tttttctacg atggccatgt attcttcacc cattggtttc agtgcttcta aagctttttc
   117481 ttttgcttct tcgtacgtaa aggtaattgg agcttcccct aagaccggtg tataaagatc
   117541 atacatgtgc agtttttcca cttctaataa acgtttccgt aattccatgt atcgatgtaa
   117601 caaaggcaaa tgcttgttta ccacgtctac caaagtatcg tatacacttt caggaatatg
   117661 attattgctc aaagacgctt ctctggcaga gctgtaatta cggactttcg ctttaaaatt
   117721 atgtcctttt atatgtgtgc ctaaagtaga agcaaatgta tttctaaatt gttcgtaaac
   117781 actgtacaat cccttaaatg ctgcttcgcg cacccttcga tccgtgcttt ctagcaactg
   117841 accatacacg ccatgagata attggactat ttcaccattt tctccttcaa tcgttggaaa
   117901 aactagatct gcattattca aaacagcaaa tgtatcactt gaagcatcaa agatttcacc
   117961 tgctccagca agaagagatt cctgctcagc agataagaca tgggctcgat tatctactat
   118021 ttgctggata taatggcgat agacttccaa ttttggttct tctttgaaat attgccaaat
   118081 ctggtcatct gacaattgca atatttctgg ttcaaaccag gaaacggctt cactaacttt
   118141 cgaaaacaga ctgcttgctc ttgcataaag cgcttggtaa tctgtatttc cagtgtcttg
   118201 atcgttttta aggtgcgcat atacataaat gacttcagtt tggcgataaa ccctcaatac
   118261 gaattcaatc gcatttaaaa attgagaagc gccttgatca agtgttcctt tgtgtttttc
   118321 agattgtttt aactcttctg ataattccaa atatttctca tcaaactctt ggtcgcttga
   118381 aaagatcttg gtcaagtccc aagttaaatt ttcaggcaat tcttctcgtt ttggcaactg
   118441 ctttacttcc atgaaatcca ctccttttct tcccttagct ctatctatca aaatagatca
   118501 tagtctaaca tccacatgtc acagcatcta acttttctac tcattcatgt gtctgcttcc
   118561 atcaatttta gcataactaa atcttgtttt acatagaaaa ccgattccta gcctattttt
   118621 atacttacta ttttttcaaa gaagacaagt gtatgcattc gttaaaaaac tgctgataga
   118681 ccatctcttc atcaatcata ggaaaaagcc attccctttt atgttctttt atttggcaaa
   118741 gccatgagtt gaaatcagga actttctggt tttccaaggc ttcttcgtac aacattcgat
   118801 aaagaaaaac ctgttcttgt aaataaaaga aaaaccgact tttttgatag atccacgatg
   118861 atagatgcaa aagatgttta tgacgcaagt agcattgttc ttgtatggat actgtattct
   118921 tttgcttgtg aataagttgg cgtgtcagcc atttcttccc atcttcactc actttttcta
   118981 tttttttcat ttggttcatt ttaatttcgt tactagtgaa tatttcttta aggtccctac
   119041 tagaaaaagt ccagcagcta ctgcaaaagg aaatatgccc tgatacagtc tctgtaatat
   119101 gatgatacaa ataaagcttt tgtttcttga gatcagcttt ccagcaatgc actcctcttt
   119161 ttctattata gtagcagcaa cttttttcta tcaatgagaa ttgcgattgt ccaagaaaag
   119221 aattaccaag tatccaccat acttggtaac tgttattcaa ataattttgg gttctttcaa
   119281 taaatctctg gtgagacagt ctagaacatt ggatttctat tgctagattc gccaacaaaa
   119341 tatccggcct ttgccgcaac ctcggcaaat aggcttccaa aaatactggt tctactgact
   119401 gtcccagcca atccatgaag cattccttta actgtaagtg ctcttttgat tctctttcac
   119461 taaagaccga acagttatct gatttttgat gggcaaaatg agcacatttt ttctttccct
   119521 ttttcaaaat cactcttttt cgacagccac gacaataata tttctttcct ttttctgcat
   119581 gtttagcaaa acagcactta ttatattcat tcattgcaag cagcattttt ctccctctga
   119641 acttatttac gtctaagaat ttatttacac gaaaaaagag ggcgtgaaaa agctattctg
   119701 catcaagtaa taagaacagc taaacaaaaa tagttcccaa tatttttcgt ttggttgggc
   119761 ttgttaccgc agatgcaagc ttttgaacac atttatacga aaaaaagact gcgacacaat
   119821 ttttgtcaca gtctcttact ataatgctga tttatacaaa ataaaatttc gttcgctcga
   119881 tagcattacg cgccatcaga cattgtccat attcattcaa tgtttctggt gtacgatcgc
   119941 tcttttcagc aaactccaaa attcgagcaa tctgattctc tacatccgct tggttgagat
   120001 tttccatcca gaagtgaacg actaggtaat agcgctcttc gaataaatac aaatcagtcc
   120061 aagcagactc tagttcgaca tctgttgcaa gttggatcac ttgttcaaaa tcttcaaaag
   120121 caaaagttgc ttgtctttcc tgttcttcta gggcgcttcc agataattct tcctccggat
   120181 cgctgccaat aatctgctga cgaagaaagt cactcacatc ttctgaatca acagtagaat
   120241 cttctgattg agaaatttct tcatccggaa gatttttact gataaacagt tctaatccgt
   120301 ctccttttgg caaaacttgg aaagtgacag cttcgcttcc tcggaactcc tcttcgatat
   120361 caacttcttc caaaatacta taaaagaaat tttcgatttc tttgtgattg ccaagtaaat
   120421 ccaaaaatga aacgccccgt tcctctaaat cttcatgacc aattagtaca cggatcgtat
   120481 tttcattaat atgttccatt tccattttgc tacacctcac tttgccacaa tgtttaatat
   120541 agattcattg tagcgaaatc agcttaaatg taaagaaaaa aaatctcgct gttaagcgaa
   120601 tttaataaaa ccagcggatt tttcaacctt tcaagctatc ttatttaact ataacatttt
   120661 tggcagacga atactatata gccgactttt cagctaattt tccctctcta tttttcgtgc
   120721 aatcatcatc ttctactacc tttttataca tctaatcaag aatacttttt gtaaaaacaa
   120781 aaaaacttgg aaaaactatc tttgtaatag t
//
LOCUS       DACGLI010000002        93455 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.002, whole genome shotgun sequence.
ACCESSION   DACGLI010000002 DACGLI010000000
VERSION     DACGLI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 93455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.002"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            85..972
                     /locus_tag="IXT22_000116"
     CDS             85..972
                     /locus_tag="IXT22_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4861516.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="IXT22_000117"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="IXT22_000117"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAQ4861517.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="IXT22_000118"
     CDS             2274..2720
                     /locus_tag="IXT22_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4861518.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="IXT22_000119"
     CDS             2993..4345
                     /locus_tag="IXT22_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAQ4861519.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="IXT22_000120"
     CDS             4516..4803
                     /locus_tag="IXT22_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861520.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="IXT22_000121"
     CDS             5029..5472
                     /locus_tag="IXT22_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4861521.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="IXT22_000122"
     CDS             complement(5478..6662)
                     /locus_tag="IXT22_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAQ4861522.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="IXT22_000123"
     CDS             6930..7628
                     /locus_tag="IXT22_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAQ4861523.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="IXT22_000124"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="IXT22_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAQ4861524.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="IXT22_000125"
     CDS             complement(8438..8971)
                     /locus_tag="IXT22_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861525.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYSPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="IXT22_000126"
     CDS             complement(9268..11649)
                     /locus_tag="IXT22_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4861526.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="IXT22_000127"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="IXT22_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAQ4861527.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="IXT22_000128"
     CDS             12350..12889
                     /locus_tag="IXT22_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAQ4861528.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="IXT22_000129"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="IXT22_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAQ4861529.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="IXT22_000130"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IXT22_000130"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="IXT22_000131"
     CDS             13996..15162
                     /locus_tag="IXT22_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAQ4861530.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="IXT22_000132"
     CDS             15208..16704
                     /locus_tag="IXT22_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAQ4861531.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="IXT22_000133"
     CDS             16785..17468
                     /locus_tag="IXT22_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4861532.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="IXT22_000134"
     CDS             18113..19303
                     /locus_tag="IXT22_000134"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAQ4861533.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="IXT22_000135"
     CDS             19405..20358
                     /locus_tag="IXT22_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAQ4861534.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSGNVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="IXT22_000136"
     CDS             20427..21776
                     /locus_tag="IXT22_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4861535.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="IXT22_000137"
     CDS             complement(21959..22282)
                     /locus_tag="IXT22_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861536.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="IXT22_000138"
     CDS             22411..23574
                     /locus_tag="IXT22_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861537.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="IXT22_000139"
     CDS             23644..24993
                     /locus_tag="IXT22_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4861538.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="IXT22_000140"
     CDS             complement(25038..25469)
                     /locus_tag="IXT22_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4861539.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="IXT22_000141"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="IXT22_000141"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAQ4861540.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKEHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="IXT22_000142"
     CDS             28699..29295
                     /locus_tag="IXT22_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4861541.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="IXT22_000143"
     CDS             29417..30565
                     /locus_tag="IXT22_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4861542.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="IXT22_000144"
     CDS             complement(30603..31016)
                     /locus_tag="IXT22_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAQ4861543.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="IXT22_000145"
     CDS             31095..31526
                     /locus_tag="IXT22_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAQ4861544.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="IXT22_000146"
     CDS             complement(31625..31858)
                     /locus_tag="IXT22_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAQ4861545.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="IXT22_000147"
     CDS             32041..33711
                     /locus_tag="IXT22_000147"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAQ4861546.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="IXT22_000148"
     CDS             33858..34244
                     /locus_tag="IXT22_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861547.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="IXT22_000149"
     CDS             34231..34929
                     /locus_tag="IXT22_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4861548.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="IXT22_000150"
     CDS             34934..35398
                     /locus_tag="IXT22_000150"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAQ4861549.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="IXT22_000151"
     CDS             35395..36306
                     /locus_tag="IXT22_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4861550.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="IXT22_000152"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="IXT22_000152"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAQ4861551.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="IXT22_000153"
     CDS             37094..38377
                     /locus_tag="IXT22_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAQ4861552.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="IXT22_000154"
     CDS             38390..39316
                     /locus_tag="IXT22_000154"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAQ4861553.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="IXT22_000155"
     CDS             39335..40615
                     /locus_tag="IXT22_000155"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAQ4861554.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="IXT22_000156"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="IXT22_000156"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAQ4861555.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="IXT22_000157"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="IXT22_000157"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAQ4861556.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="IXT22_000158"
     CDS             44940..45716
                     /locus_tag="IXT22_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAQ4861557.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="IXT22_000159"
     CDS             45713..46645
                     /locus_tag="IXT22_000159"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAQ4861558.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="IXT22_000160"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="IXT22_000160"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAQ4861559.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="IXT22_000161"
     CDS             47365..47994
                     /locus_tag="IXT22_000161"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAQ4861560.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="IXT22_000162"
     CDS             47982..48296
                     /locus_tag="IXT22_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861561.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="IXT22_000163"
     CDS             48334..48975
                     /locus_tag="IXT22_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4861562.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49006..49710
                     /locus_tag="IXT22_000164"
     CDS             49006..49710
                     /locus_tag="IXT22_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAQ4861563.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="IXT22_000165"
     CDS             49707..50609
                     /locus_tag="IXT22_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4861564.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /locus_tag="IXT22_000166"
     CDS             complement(50767..52473)
                     /locus_tag="IXT22_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAQ4861565.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52663..53286
                     /locus_tag="IXT22_000167"
     CDS             52663..53286
                     /locus_tag="IXT22_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861566.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53736..54785
                     /locus_tag="IXT22_000168"
     CDS             53736..54785
                     /locus_tag="IXT22_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861567.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54782..55663
                     /locus_tag="IXT22_000169"
     CDS             54782..55663
                     /locus_tag="IXT22_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861568.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55666..56436
                     /locus_tag="IXT22_000170"
     CDS             55666..56436
                     /locus_tag="IXT22_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4861569.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56715..57569
                     /gene="aroE"
                     /locus_tag="IXT22_000171"
     CDS             56715..57569
                     /gene="aroE"
                     /locus_tag="IXT22_000171"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAQ4861570.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57747..58910
                     /locus_tag="IXT22_000172"
     CDS             57747..58910
                     /locus_tag="IXT22_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4861571.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59027..59437
                     /locus_tag="IXT22_000173"
     CDS             59027..59437
                     /locus_tag="IXT22_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4861572.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59611..61839
                     /gene="topB"
                     /locus_tag="IXT22_000174"
     CDS             59611..61839
                     /gene="topB"
                     /locus_tag="IXT22_000174"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4861573.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            61977..62294
                     /locus_tag="IXT22_000175"
     CDS             61977..62294
                     /locus_tag="IXT22_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861574.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            62454..62690
                     /locus_tag="IXT22_000176"
     CDS             62454..62690
                     /locus_tag="IXT22_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4861575.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62687..63086
                     /locus_tag="IXT22_000177"
                     /pseudo
     CDS             62687..63086
                     /locus_tag="IXT22_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(63753..64697)
                     /locus_tag="IXT22_000178"
     CDS             complement(63753..64697)
                     /locus_tag="IXT22_000178"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4861576.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64993..65937)
                     /locus_tag="IXT22_000179"
     CDS             complement(64993..65937)
                     /locus_tag="IXT22_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861577.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66158..67372
                     /locus_tag="IXT22_000180"
     CDS             66158..67372
                     /locus_tag="IXT22_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4861578.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67394..69409
                     /locus_tag="IXT22_000181"
     CDS             67394..69409
                     /locus_tag="IXT22_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAQ4861579.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69492..70865)
                     /locus_tag="IXT22_000182"
     CDS             complement(69492..70865)
                     /locus_tag="IXT22_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4861580.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70891..71175)
                     /locus_tag="IXT22_000183"
     CDS             complement(70891..71175)
                     /locus_tag="IXT22_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4861581.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71177..73192)
                     /locus_tag="IXT22_000184"
     CDS             complement(71177..73192)
                     /locus_tag="IXT22_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4861582.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73371..73676)
                     /locus_tag="IXT22_000185"
     CDS             complement(73371..73676)
                     /locus_tag="IXT22_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAQ4861583.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73765..74796)
                     /locus_tag="IXT22_000186"
     CDS             complement(73765..74796)
                     /locus_tag="IXT22_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAQ4861584.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75003..75878
                     /locus_tag="IXT22_000187"
     CDS             75003..75878
                     /locus_tag="IXT22_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4861585.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76030..76872)
                     /locus_tag="IXT22_000188"
     CDS             complement(76030..76872)
                     /locus_tag="IXT22_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4861586.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76964..78841)
                     /locus_tag="IXT22_000189"
     CDS             complement(76964..78841)
                     /locus_tag="IXT22_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4861587.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78838..80259)
                     /locus_tag="IXT22_000190"
     CDS             complement(78838..80259)
                     /locus_tag="IXT22_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4861588.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80262..83651)
                     /locus_tag="IXT22_000191"
     CDS             complement(80262..83651)
                     /locus_tag="IXT22_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4861589.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83908..85299
                     /locus_tag="IXT22_000192"
     CDS             83908..85299
                     /locus_tag="IXT22_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4861590.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(85372..86019)
                     /locus_tag="IXT22_000193"
     CDS             complement(85372..86019)
                     /locus_tag="IXT22_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4861591.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(86027..86713)
                     /locus_tag="IXT22_000194"
     CDS             complement(86027..86713)
                     /locus_tag="IXT22_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861592.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86719..87792)
                     /locus_tag="IXT22_000195"
     CDS             complement(86719..87792)
                     /locus_tag="IXT22_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4861593.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            88014..88688
                     /locus_tag="IXT22_000196"
     CDS             88014..88688
                     /locus_tag="IXT22_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4861594.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88693..90033
                     /locus_tag="IXT22_000197"
     CDS             88693..90033
                     /locus_tag="IXT22_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4861595.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90182..91168)
                     /locus_tag="IXT22_000198"
     CDS             complement(90182..91168)
                     /locus_tag="IXT22_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAQ4861596.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91892..92923
                     /locus_tag="IXT22_000199"
     CDS             91892..92923
                     /locus_tag="IXT22_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4861597.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            93032..>93455
                     /locus_tag="IXT22_000200"
     CDS             93032..>93455
                     /locus_tag="IXT22_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4861598.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT        29895 a        16575 c        18966 g        28019 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggagaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtggaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaagaac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacctc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagctgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggtat aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa
    52681 gtagttaaat cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat
    52741 ccaagtaagt attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt
    52801 gcaatgtttt tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg
    52861 tccataccaa ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa
    52921 caaagccggg cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg
    52981 cttgatgttt ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat
    53041 ccgatcgttt atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg
    53101 acatttattt tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga
    53161 ataactgatt ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc
    53221 aaacaattag aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct
    53281 aattgagaca ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga
    53341 acaagtgatg tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa
    53401 ttcaaaaatt cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt
    53461 atcaaaacgt atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt
    53521 attaatggtg agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat
    53581 ctatgctaga catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta
    53641 aagacaatga ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata
    53701 ataaataaaa agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag
    53761 ttgtagtaat tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg
    53821 aaaaagaaag tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat
    53881 acgtgagcca tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag
    53941 aaggattaaa agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga
    54001 gcaagctagc cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa
    54061 tcgcaacacc tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag
    54121 gtgctgtaac ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta
    54181 atgtaacagg tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt
    54241 tgttgccaaa tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat
    54301 accaagtagc acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg
    54361 cggtgccttc cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt
    54421 ttatctatgt tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag
    54481 caaacaaagc aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac
    54541 tagcaacaat cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag
    54601 aacttgcgag tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg
    54661 atacagtgat caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga
    54721 aggaaaaagc caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca
    54781 aatgatcgta tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt
    54841 catgacttat cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg
    54901 tgctgctgtc tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt
    54961 aggcgtaggt gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa
    55021 gataccggtt attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt
    55081 tgtgatgcga acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca
    55141 tcgctttggg ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat
    55201 cttgattgct gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac
    55261 aggagacaac gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt
    55321 aggtttaact ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga
    55381 cggatatgca gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat
    55441 catcggtgaa gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt
    55501 cggcagtatc atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac
    55561 ttatctgaag ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa
    55621 gaaagcactg aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg
    55681 acaatcaaaa atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg
    55741 gatgaaatta accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt
    55801 gctggaaaaa gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg
    55861 atctctttta aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt
    55921 tctcgagttt tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat
    55981 ttgctacttg cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat
    56041 caaaaagaag attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg
    56101 gatactccag cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg
    56161 acgatcacag ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa
    56221 acagctaaag cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt
    56281 ctcatgatca cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc
    56341 caaaaaggga aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc
    56401 gaccttttgc agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag
    56461 tagaaggact tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata
    56521 aacaattaaa catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa
    56581 atagaatatt ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc
    56641 tagacgtttc gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac
    56701 aaaggaggaa taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg
    56761 cttctcacag tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg
    56821 cggtgtattt agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc
    56881 gaacttttga tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt
    56941 atctggatga ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg
    57001 aaaagggtcg tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag
    57061 aagctgggat ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa
    57121 aggcagtcac tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa
    57181 acaaccaaac attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt
    57241 gtaagataaa agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa
    57301 gctgtcttct agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc
    57361 tcttagatat aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta
    57421 gagaaacacg tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg
    57481 gcatgttgat ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga
    57541 tccatgtgat tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct
    57601 cgcataaacg gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt
    57661 tttattaaat tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta
    57721 tcagtaagaa acgaggagga accacaatga gtcggatgga tcgctataag gacatccata
    57781 agaaggcgaa acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac
    57841 gaacgcgtat ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat
    57901 ttgaacattt gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac
    57961 aacaaaaaaa taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa
    58021 gaaagcgatc gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag
    58081 gtatctcatt ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga
    58141 cttcagaaac ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg
    58201 gaagtgatac acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg
    58261 atggtccttc ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc
    58321 caggggtagg acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc
    58381 gtcaaacttt agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca
    58441 aatcgtttga aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa
    58501 aagatctgaa tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg
    58561 ttcttttgca gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac
    58621 gccaacagca agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc
    58681 gtgcacctta tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt
    58741 tcttgacgaa aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg
    58801 tgccagtaga cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa
    58861 ttgataatca aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa
    58921 gatcaagaag aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa
    58981 aaacgctttc ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct
    59041 gaacttcaaa aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga
    59101 agcatcaggt atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga
    59161 agaagcaaaa aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt
    59221 tgcagatacg ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt
    59281 catccagaca agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg
    59341 taagattgag atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga
    59401 tcgatttggc atcaactggc agattaacca agagtgacag ctaaagatga atattttctg
    59461 gaaacatcaa gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg
    59521 actatacggt atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc
    59581 cgcaaaaaat taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct
    59641 tcacaagcaa aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat
    59701 gaaatcagcg atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg
    59761 gtagatatgg ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat
    59821 ttgcctattt tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt
    59881 tcgatcgtaa aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat
    59941 cgagaaggtg aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa
    60001 aagaactatt tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt
    60061 aagaatctcc aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag
    60121 aacgctgatt ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga
    60181 aaagggattg atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt
    60241 tatcagctgc aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt
    60301 ttaattacga caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa
    60361 acccaagaag agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac
    60421 ggacggattc ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg
    60481 ctatctagtt tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt
    60541 gatgctgctc aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt
    60601 tacattacag aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt
    60661 ttaggaatag aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg
    60721 aaaaaagttc aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc
    60781 tttgcgaagc tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg
    60841 gctatgtttg ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa
    60901 ttaaagctaa aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc
    60961 atcaagtcaa aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca
    61021 gaagtagaac tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga
    61081 acgttgatca cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa
    61141 attctcaaag aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat
    61201 cttaagcaga agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga
    61261 atcactcttt gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg
    61321 cgctgggaag ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta
    61381 gagaatatca aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag
    61441 gtagactttt cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac
    61501 gatcaattag gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc
    61561 gctacatgct tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag
    61621 ctgactaaaa cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa
    61681 ggttttactg gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca
    61741 atcggttttt cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa
    61801 gaaacatcaa gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg
    61861 aatatttatt ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat
    61921 caagcaaaaa cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga
    61981 aaaaagtgca ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc
    62041 aagcatttct aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa
    62101 cagcatattc accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt
    62161 atttttttca taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg
    62221 tggtggtagc ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc
    62281 aatattttgg ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt
    62341 tgtcattttt tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac
    62401 ttggatataa tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa
    62461 aaatgaaaaa gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag
    62521 aagtaaaaga attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg
    62581 atggttctgt acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt
    62641 cgatcatgaa tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc
    62701 gactaaagaa attatcaaaa tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa
    62761 tgatcggtgt aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag
    62821 tattcaatca agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt
    62881 tagctaaaaa acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt
    62941 tgtttcttca attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta
    63001 tcataatgat taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt
    63061 atttacgaca aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag
    63121 catgtcatta aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat
    63181 aaaaatatgg aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag
    63241 tgaatagtag gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta
    63301 cataatatat attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt
    63361 tatcaaaaat cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg
    63421 cagtttttct tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag
    63481 ttaatcaaat atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt
    63541 ttaattaacc acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt
    63601 tcatatgttc atatgtacgg atacattttc ggaccgatta attttaacca ttctgtttat
    63661 ttgcttacct attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag
    63721 ttttaggatt tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt
    63781 aaagcacttg ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca
    63841 acttcacgaa caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg
    63901 tcgtattcac cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata
    63961 gcttttacga tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca
    64021 atgatctcat aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca
    64081 atacgatggt ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac
    64141 catgcagcaa cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg
    64201 tcaactttta atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca
    64261 gtaccgataa cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata
    64321 tctactgggt ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt
    64381 acgatttggc gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt
    64441 ttttggttga taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca
    64501 cctgaccata cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct
    64561 tccccttctg ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg
    64621 ttgatcattg cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta
    64681 cgacttgttt ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa
    64741 aagtatagtc ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat
    64801 ttttgatgga aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta
    64861 tatcccctga taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg
    64921 caacgatata ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga
    64981 aagattttct tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt
    65041 gaataatttg aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa
    65101 cgaaaaactc gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag
    65161 ttcttgaaag gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta
    65221 gccaaaatga gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc
    65281 taatactcta agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc
    65341 taataaatga gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt
    65401 atgactgtat gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact
    65461 tgtttttccg ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt
    65521 tatcaaaaaa gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga
    65581 taaggtttct tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat
    65641 tctttgagta gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc
    65701 tccattaata atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg
    65761 tgtatgctcg ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg
    65821 aaatagatcc cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc
    65881 attgatattc attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa
    65941 aaatgtctaa ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc
    66001 ttattagttc acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt
    66061 tctatggttg ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac
    66121 tatatttttg ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat
    66181 gaaattttct ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc
    66241 aattcccagt atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac
    66301 gactgctccc tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa
    66361 aatcggacaa aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct
    66421 ccccctcttc tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg
    66481 ctttggattg atcaattctt tggcagtcag catgattgct gccttttatc acggagatga
    66541 acgagcctct atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac
    66601 atttgttgca ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat
    66661 cagcttacct attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact
    66721 tcaatcgcat ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag
    66781 ttatggtatt tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc
    66841 cacagtcctg acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat
    66901 catgcaattg gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca
    66961 tcgctatatg cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac
    67021 tgtgataaac ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt
    67081 attcattcct tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt
    67141 caatacttca atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt
    67201 gctctttctc tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag
    67261 tatcttgctg ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa
    67321 gacagtgata agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg
    67381 gaggtcgtgt aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga
    67441 ctttgagatc cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg
    67501 gccagcgtac tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt
    67561 tcttgatcaa ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa
    67621 tggacaaaaa catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg
    67681 tatctttgta ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa
    67741 atcagatatt ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc
    67801 gctttatgtc gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca
    67861 tccagtcact gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa
    67921 tggctgtgta gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg
    67981 agagtccgat gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac
    68041 aagaaaaatg aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac
    68101 tggaatggtt caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt
    68161 ttcaagcgat tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt
    68221 atgtagtgat ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga
    68281 tgcgtatcaa tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg
    68341 aacgatatta gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga
    68401 ctattcgatc ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga
    68461 atttttacgc atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac
    68521 gaatgaatta gggtttattt atgggagagc aaaagattgg atatttattg attggtctga
    68581 aatggataaa gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc
    68641 catgatcact tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac
    68701 tcatctctat caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga
    68761 tgaagaactt ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca
    68821 tgcgaatatt ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt
    68881 aaagaatgtc ttattgaatg acactatcac acagattact actccatatt tcaaattcta
    68941 tgaacaagat gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga
    69001 ttattgggga gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac
    69061 tcaaacagga aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca
    69121 tgcatgggga gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac
    69181 aaagccaggt tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa
    69241 ttgtacgcta cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt
    69301 gattacttct gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct
    69361 agcaaaacag ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact
    69421 gcttgcgaca tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt
    69481 ttgaagtttg cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga
    69541 aagctagata atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga
    69601 ccgtattctc ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat
    69661 gtagaagaag cgattttaag atctcctaat actggaagga taaataatgg cagccaacta
    69721 atcaataagc tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg
    69781 ccgaagacac cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact
    69841 gtagtttgca agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa
    69901 aagccaatta atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt
    69961 ttagaatcgg gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac
    70021 accattcgaa ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc
    70081 agtgcaaaga ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca
    70141 gctaacaaag caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa
    70201 tctcgcaaaa agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt
    70261 ccaaaaaact ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac
    70321 gcaacttgat tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata
    70381 gttaatagtg ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac
    70441 cccgcgctta ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta
    70501 agaaaaatga atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact
    70561 agcatgatca aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca
    70621 ttgctaggaa ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt
    70681 agtgaattac tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg
    70741 atagttcctt ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca
    70801 atcaaagaaa cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta
    70861 tccattgata gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt
    70921 ttcttttact tcttcgctgt caatgatcga ttgcaaaggt acgagctttt catcaggtat
    70981 agaagttagc gtatctttca aagaatgctc aatgaagaaa taatcagcca tatcgctaga
    71041 tacacttcca acatccgtat gacttacttc aaactcgtcc acatctgctc caagatctgc
    71101 aagtgcttgt ttgatgttca tctctaccat aaaacttgtt cctaatccac tttgacatac
    71161 tgcaaaaatt ttcatatcat tcgtctcctt ttcttatgat cgctaatatt tcttcttttg
    71221 ttgatgcgtg taataaatct tgaagatttt gtttattaga aagtagcttt gttaaatttg
    71281 ccaaagcccg aagatgtgcc tcattatcga tagcagctaa acagatgaac aaactaatgg
    71341 gatgggctgg attatcaagc agatccacag gttgttgaag tttcagcaaa gacatcccta
    71401 cttcgtttac gccatcttct ggacgagcat gaggtaatgc gatgtgatcg ccaatatgga
    71461 taaacgcacc atactgctcc acgcgctcga tcatagcttt gatataactt tcttctattt
    71521 tattttctga taatagcggc tgtgcggcaa atgtgattgc ttcttgccag ttttttggtt
    71581 gatccgataa ttggatcatt tcttctgtta ataattcaga tagcatagga cgttgatcct
    71641 ccttcttttc taaaagtttg ttcattttac gatttaatac ttgatagagc ttttcttcgt
    71701 ctacgccttc ttttaattcg atataaggca gtagcgccga caacaattct tgggcagaag
    71761 gcattgaaaa tcctggtatc agccaatctc tttgtacttg attgatcagc tgattttttt
    71821 ccaagtcagt catgattgga tgcagaacat agagagactt tttcttatca gtaagtgtga
    71881 gaggtacagt agaaaaaata atatcgtaag aagtttcgtc aacctcgtgt aagcggtcag
    71941 ctgaattagt ctctgtaaaa aagatcatcg ggaataattg ctgaagttca ctttttaaga
    72001 tcaatgaaga gctaatgcca cttggacaga cgatcacggc tcttattttt ctatttcttt
    72061 cttctgcgtc cgcttttctg atctctccgc caaatagtat agtgaaaaaa ccaatctctt
    72121 cttcagggat gctcttccct attcgtcttt ctaacggaag taatgctttt cttgtcattt
    72181 cgtagatgga agcatattga tgcttaattt gatcgatcat cacattaggt aaataaaaag
    72241 aataggaaat acgaaaatag gcagggacca agtgataaaa gacattcatc aataattcac
    72301 gaaacgaagc aaattctacg gccatcagga attccatgcg atggatgact tctgaagaac
    72361 attccagcaa aaaatcaagt gcaggctcct ggacatctcc ttcaacgatc gatgctaagc
    72421 aaagagagaa aaatataatc tccgaatttt gatgttcgga atagccaagg ccagtcaata
    72481 cttgtcgact aatgtcagtg actgcaagag aagccaacag ttcagcatct tttaccagtt
    72541 ccatggatgt ttttccaatt cgaatggttg tcaaactcaa ataataagct aattcatcca
    72601 ttcgatttgg tgcgaatcga agatctgata gtgaaatcgt tttatctagc aaatctctaa
    72661 ctttggcgta ataatcaatg gaaagggttg cggttaaata cgtgagccca aatcttccag
    72721 caagtgactg catcaaacga gcagtgcgat tttttgcttc tcttcttaat attgcttctg
    72781 accctagcag cctaaaacca gttttcctag tatacgacag ctgacaatct tccacttcta
    72841 attcatttct tatctttttg atatctgaca ggactgtccc tttagaaacc tgaagaaaat
    72901 cttgaaaatg aaaaacagaa acagacgttg cagtcgaata aaccatcaaa taaagaagat
    72961 ctcttcgctc ttgttcggta tacacagctt caaatcgagt aatatccaaa aatttttctg
    73021 cccagtcgat tgctcggaat ttctttatac ggatacgggt atcatccaca tattcggcaa
    73081 aaggagttaa ttgtttgatc gcctcgcttg tatttacttc gatgatctct gctgcttttt
    73141 ctagactgat ttctcttggt gttttcagga gataactaat tttgtagttc acagcgctgt
    73201 tcacctccta cttatattct agtatggtag cgcttttaaa tcgaggggtg tttggtacaa
    73261 cttacagttg gatttttttt acgactgtac cgaacgattt ctatcgaatg gatacagaaa
    73321 aaaagcaggt gaccaaatgt ctcctgcttt tatgaattga tttcgtccga tcaatgatga
    73381 tcatgtttat tttttgaggt cagttcttca aatttttctt tgacatcttc aaccgctttt
    73441 tcgatatctt tttcaaagtg attgggctca ttaggctttg tttcctcttc tacagaattt
    73501 gaaccagata aagctgtttc tttattttct gtttcaccag agtttgtgcc agctaatgat
    73561 tcttctttgt cttctgtttc accagaatta gttcctgcta aagccacttc ttcttctgtt
    73621 ttaggggcca ttgaacctct taatcgtttg tgtttttcac cgtcataatt tgtcatgttg
    73681 gttcctccta gtagttctat actttttcat cgtacaataa gacagtttat gcgtcaaaaa
    73741 acaaacccga ttcttacaaa tatgtcatat ttttccttct gattcttgaa tgcttttgat
    73801 tccttcttcc aaaattttca tttgtaagat tgtttcttca tctttgatga ctttttctgc
    73861 gccattaact aatgtctcgt aaatcccttc gtagacacgg ctgtaatcac caacctcgga
    73921 aattactttt tcttcatgat aactcccttg ttcatctata taggtcaata caccataatg
    73981 ttcgggcaaa tcgataccaa agtcttcatg atcaggcatg taaaacattt tcagatgttc
    74041 ttcttgtcga tcttttgttt gtttcacgaa catccctttt tttccgtaaa cgacgaaact
    74101 tggacgttct ttgatgcgga aataactgga ttttatcgaa attttcatat ttccatagaa
    74161 aaaatccaga tcgaagtaat cattcattcg tcctttccct aaaagttgac gtacatcata
    74221 gctgatatca tctggttcgc cgaaataaga aagaacttga tctactgtat gacaagcatg
    74281 tccatataaa tagctgttcg cagtagaaaa ttcatgcgta ttttctggta cttccggtct
    74341 gaaataatca taatgcattt ctacttctaa aatatcccct aattttccgc tttcgattac
    74401 tttttggact gtcaagaagt cagaatcgaa ccgtctgttt tggtaacatt ggataaatag
    74461 acctttttct tttgctaatg caaataactc ttctgcttcc tttgacgttt ctgcaaaagg
    74521 tttctctact agtacattct taccatgttc gagtgccatt tttccatatt cataatgaaa
    74581 ttgactaggt gtagtgatga caactaattg gatctcagga tcatcccaaa gatcagacag
    74641 ctgatcagta tattcgatgt cttcgaatgt tttccacact ggttcagatg gggaaaaaat
    74701 ttttttgata ttgattttgt tcgtaagttt tcttgaaaaa ggcaaatgat agcgatttgt
    74761 actctttcca ttgccaagat aagcgattgt aagcatgagt ggtgcctcct tttattgatg
    74821 ttttcagtat atcctagaaa agcgcagaaa gtatttataa tagctattct ggtaaaaaag
    74881 ttcagaaaaa cacttgttat cattcggttt ggtgaaatta atgttcaaag taaggataaa
    74941 aatcaaaaag atagtagcgg aaccaagtgt ttatcagtaa gatagaattt ggaggtcaga
    75001 tcatgcttat tgaagaaaaa ctaacaaaac aagagttgtt taccacgaca gagaaacgga
    75061 ttgtcgatta catccgtagg aatatcgaag ctgcagtcta catgacgatt gaagaattag
    75121 caaaagctac gtatacttcc cattcagcta tcattcgttt atgcaaaaaa atgggattca
    75181 gcggatttaa agaattccgt ttcgagctgg ggcgggaagt tcatcaattg attgctcagt
    75241 tcaatcaaac gattgatcct aattttcctt tttcaagtga agatagcact cagcaaattg
    75301 caaagaaaat ggcggattta tcgatccagt caataaaaaa agcacaattg cagattgaac
    75361 atgaagattt agatcaaatc ggtaaagtat tgaacaaggc acagcgaatc tttctttttg
    75421 caaaaggtga ttctcaaatc acggcaagga aattccagaa taaaatggtc aagttgaata
    75481 agtttttgat catggctgaa gaatacagtg attcttcttg gaatgcagcc aatttgacta
    75541 gcgaggattg cgccattttt attagctaca gcggtcgcat ccatcattat gaacgaataa
    75601 tgacctattt gaagcatgta gaggccccta ccttgctgat taccggaaat cagcattcag
    75661 aaatggccaa acaggctgat atgtgtcttg ttatatcgca ggaggaatat gattttgcta
    75721 aagtagcgac tttctcctct caaattgcct tcgattacgt attaaatacg ttattctcag
    75781 tgatatattc tcaaaatttt gaagagaata tccgcaactt gaaaaacaaa caagaattga
    75841 tgcaaaaagg ccttcttaaa gaatatcgga aaacttaaga aaagatcctc atttagtaat
    75901 aagaaagata gtgtttgata ggctctcttt gatatcatca taaaaacagg ctgaagtttt
    75961 ctttttcaaa cctcagcctg tttgtttacg gaacgattcg aatagatata ttatagaaat
    76021 gaggaatagc taacttctgt ttcttatttt gaacgattga cgaaaaagat atataagaag
    76081 gaggaaaatc agtatacatg cagctaacaa tccatacagg aaaaatcgtt tgttctcgga
    76141 tactttctgt acttcttttt gaacttcttt tgcatgataa ggaacccggt gccctctgac
    76201 aagtaagcga tgactgttga ccatataagg tgtacaagtt aggagtgtca cgaaatcctg
    76261 ccctttttcg attctcagat cttttgtatc agtcggttct accgtcttga tctgatcgac
    76321 ttgataagcg agtgtccgtc cattgatttc gatatagaaa gaatcaccta aagtcagttt
    76381 cggtaagtct gtgaacaact ttgcttgagg cagtcctcga tggctggaaa taacggcatg
    76441 tgtattttct ccccccgtag gataagacgt tccttccaat aatgaggcac ctttttctag
    76501 cagcacagta ttcgtttcat caaaaattgg caaatggaca ttgatctcag ggatcgtcaa
    76561 aataccgatc gtatgtttct caaaataggt tctatccttt ttcgcaggtt cttttttctt
    76621 agtaaaggga tctgcacctg gatttccacc ttcttttgct aattgctggt ttttctttgt
    76681 catgttttct tggattttag ccatgacttc ttcattttct ttgaccgctt gttgctgata
    76741 atgagagatg atctgctgat ccagataatt attcagcgcg tcgctaacaa atggataagc
    76801 tagtatccct attcctgaga gaagcaagaa aagcatcagc agatctagaa gtttcctttt
    76861 ctttggtttc atttgtgttc tccttgtgat gactgtttga taataaaaga aaaaggagca
    76921 tttgcgtaat ccgctgctcc tttttccaat tcttgcaaaa agactaaatc tgactgtgct
    76981 tgcgtctagc aaagtacagt ccagcaatca gtagaaggac tactcctgca ccgatataca
    77041 catagattcc cttaccgcct gttgaaggaa gtgtaccttt gtgtttattt ggtatttttt
    77101 caggagaaat caactgtcct gctgttacat aagattgttc atcgatagta aatgctacac
    77161 ggtttgttaa tggaacatat ttttctggcg ctttcgtttc ttccagatag tacgtgccat
    77221 attttagacc tgtcacatcg attaaaccgt tacttgtggt tgtaaaaacc gttgctgatt
    77281 ctttcgccga tacccagctg acggcttttg tggatgggtc gatcgataaa tatttcgctg
    77341 tgtcactatc ttgatcacga acgacgaatt ctgctccagc aagtgtttgg tctgatgtaa
    77401 cgtcaccatc tactttaaca aatcgtttgc ccccagtaac gacatcgact gacggtggtg
    77461 tttgatcatt tgtatgcccg ttatcgacat ttgcttggtt agaaaatcct ttggttggat
    77521 ctgctttttc gttcaaatgc atatagtaaa cgaatttcaa tgtaccgcca ggagttaatg
    77581 aaggaatata attcggatca actgaaaccg tgaatccgtc tgtttgctca gtgacagaat
    77641 aatttactgg gtcgatttct ttatttccat catataaggc ataagcatac gttcctgaag
    77701 aatcattatc aaatgttaaa gcagcgtcat gagtatcgat aagtttgaat gttgtgtact
    77761 tgttttgcgt tccttcttta tcagcgatac ctaatgggat attgacagaa atctcatatt
    77821 gaattttttc accgattgcg acatcttttc cattcaattg aggtgttgtt ttatcaactt
    77881 tagacgtatc atttttgatg gtcttttcta ctggtgtttg gctatttgcc aggatctcaa
    77941 aaggcgtgat tgtttgcttt tcaatcattt ccgcattatc aggagctttt acttcttcta
    78001 aattatattt tccaacttct aaatgattaa cgatcaactg gcctttttca atagatgcct
    78061 cggcaaagtc attgttgccg atgtcataag aatgaccagt aatgaaatgt ttggctttgg
    78121 tttgatcagt tgtccaagtg tacaatccat ctgtgacact ttggatgtat tttttgacgc
    78181 ttggtgttcc ttcttcttta gaaataataa attctgctcc atttagtgct tcgttttcgg
    78241 cagtaccgat ttttgtaact ttcaacgttc catcattacc gactgtattt ttagggtaga
    78301 gatggatagt atctagttct tctgtcccgt atttataaga gccatctgct tgtttgatca
    78361 tctcatatac agggaaagct aaaaccatgt ttgcggcagc tgacactccg tcttttggtt
    78421 cttctttgat cgtgtagact gcatctttcc cattttgttt tttaggtaaa gataaagtga
    78481 catttccatc agcatctgtc gttcctgaag caactggtgt accaggagtc aaagactgga
    78541 ctgcttgttt tgctgcatcc acggacgctc ctttatctcg ttgcgcataa aattcttgag
    78601 tgacgttata aactgaaaat gaaatatcgg ctaatccttg gtattgatcg aattcgctca
    78661 tttctttccc gctgttttgg attaaaggat cgggtaaatc agtcattttc tttttatgaa
    78721 ggatgacttg agctgctgtc tcctctgcaa acactttttt tgcgccgaag ctgtttgtga
    78781 gtaatggtaa aataaggaaa aggactccta acataacgtt tattttttta tgatttttca
    78841 ttttttcact cctgttcttt ttttgataaa caaccagatt gcaaagcttg cgaataccat
    78901 accaacaacg cctaaaagtg tatttttcgt ttcgtttgtt tttggaagaa atggacggct
    78961 attttctttt ttattgacta ctttcaatat actgtccgcc tctttatcct cagaaagaaa
    79021 agttgaaatg gtaaacggaa tttctgtttc acttaaaata taaccagaag gtgcttcgat
    79081 ctcttttaat cgataacttc ctgttttcaa cccggaaatt gaaaaagcgc catttttatc
    79141 ggaaatcagg tgaagcgcat ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg
    79201 ctggaggtaa tttcctgctt tgtttttaat aaggaatact gcgccagcta atcgtttatc
    79261 tggtttattt gtctcgattt tgacaaattg cttactccct gtatatacag agactttctt
    79321 tgtactgaca ccaaaaccaa aatccagtgt tccgttgttg ttgatttcct tgttcgcctg
    79381 tgctgtactg cttagctgca tctgataaga aatggtcagt ttttttccag catatttttc
    79441 caacgaaggg atcgaaaata aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc
    79501 ttctgtcagc ttttctccat tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc
    79561 ttcatccgca ctatctgaca attcgaactt ttgatagtca aggatattta caggaattgt
    79621 cgtatgcaag gaataagtga ttttttcacc aatcgtaaaa tcatttctag gctcttctaa
    79681 taccttctca aaaggtggat cagggtagtc gttttcttca tttttaggat acaaatggat
    79741 agttgaaagt ttttgattgt tttgtccatg tacaggaaga acaactacca tattctctgc
    79801 cttttctttg acgacttctg gtactttgga ttcaatgaaa agatacgctt tatctctttt
    79861 ttcttgatct ttagcggcca gagaaaaaga agcgatacca tcttcgttgt taagagttgt
    79921 agttgttgct tctgcggtaa acataccgga agacgcaccg ttttttgcga tctctgcttg
    79981 tgcttcttct accgttttgc ccttttcccg tagatggtaa aaagaatctg tgacatcata
    80041 aacttggaat gtgacaccat ttaatcctcg atacgtttgt aataaagctt tttcttgtcc
    80101 gtcatttgga tgatttttcg gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat
    80161 ctgaaccatt tctgtttctg tttctgttgc tacctgagta aaagctggtt taaatagtaa
    80221 caagaagaga cacatactaa gccaaccaag ttttttcata tttagctgcc ccctctttct
    80281 tttttcaaaa aaagatacca aatagaaaac gcacaaccaa tcatccctac tagatagatt
    80341 cctaaacggc caattcctcc cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct
    80401 aaagaaatct ggttgttttt ggctcctggt gacagaacag attcatgatc ttgtccatcc
    80461 acttgaattg acccatcttc gtgtataact atagtaactg gctcttttag accttggtat
    80521 ccttctggtg taaaagtttc ggtcagcgta taagttccag gttttaaatt ttcgaataga
    80581 aaggtatctg tttcttgtcc atcttttggc gattctaagt ccatttctgg tccctgcagt
    80641 ctgaattttg ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca
    80701 aacgctttta gtcgattttg atgagtgagc gtccatacat tatttgtcat ctcggtattt
    80761 tttcccgtgt aaatgatttt tccatattta tcgatttgga attcataatt tcccggcgaa
    80821 gtatcatatc cggcaggacc agctgtttca acgactcgat atttaccagg tgtgagtgaa
    80881 tcaaaactgg caagaccttt ttcattcgtt gtttggctgt caattggctg ataagtacca
    80941 tttgcttctt ttttctgtag ggaaaatgct gctcctttaa gatttatctc tttgtccgtc
    81001 ccttgcatcg catacttacg tactgctaca ggaacttcaa caaaaggatt ttcaatagtc
    81061 aactggatcg tatcatcgga agtagtgact gtttttccat caatggttac cgtaccatca
    81121 gaagcgatct tgatttccca agtagtcttt ttgcttaatc catgcccttc tggagctttt
    81181 gtttctgtca gcgtataggt catttctttt tgcaatttga cattttctgg aagagaatag
    81241 gttccgtcgc catgatctgt tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca
    81301 gcgccaataa gatccttttc acctgtagag gaatttttcg ttattttcaa gtttaacggt
    81361 gtgaattgtt tagtattttt ccatgtcatt gcatctattt gttgagaatc gtatcctggt
    81421 acaggtaatt ctttgattgt ttggtaactg aatgcttgac cttgattatt gtattgaggt
    81481 agtgataata tctcttgata actttctccg ctatttgcag ataatttgtc aatgtctgca
    81541 cgttcccacg tatttgttgt atctttagct ggtttaatga ttcgaatata tccgtttttc
    81601 caagctgcag catttgtcgt atgttcccgt tgaatctcaa aagtaacttg atctggacga
    81661 tcagctagat tgttgtcaaa ttcttcccat aactttttga tgtgaagact gactccggga
    81721 gctttagcag atggtatacc gaattcagct aattcattgg tatcaatgtt tggctggaaa
    81781 gttgtcctgc cgttcatttg ataccagaaa tttggatgga agtcctcatt ttctgtttgg
    81841 attctcactt ggtaatggat ttggatttct tggtcttttc ctaaatagat ctgattgctc
    81901 ttgatggtat ttccttctat ggaaatagat ggagtgaccg ttgtaggact tgtccccaca
    81961 ctcttgactg aaagtgtacc aggctgataa atgaatggtt ctgcgattgg atcatttatt
    82021 tgtccattgc ttacagttgc tgagatctgt acagcttttt tggctaggta ttcagagata
    82081 tctgttgcat gatcagctga ttcatagtaa agatcgcctt tttcatctga tgaaaccatt
    82141 tgtcgcatac gagactctac ttctgctttt gagagaccag ctgccggatc gctttgaagt
    82201 tggatgccaa gaccatgtat ttcgattcct cgttctttga gtgccatcgc ttctccgatg
    82261 gttgcgataa acgtactgtc gattcttctg gatagattgt tttggtcagg tgcatcatag
    82321 attcttgaga ttagagaagt atttcccggc cgatcttgcg tattagaaaa ctgagttccg
    82381 taataattgc tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca
    82441 ccatccgtca gcaaaacgat cactttttta tgtccatttg gaacggatag catgcttcct
    82501 gcatctctta gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat
    82561 tttacttgat ttttcactga atcaaatgaa cccatctgta ctgcaccgtt actgtagcta
    82621 tatccttcgc ttgagtagcc gacatatccc atattgattt tgtctgtgat accgctatct
    82681 gctaaagtat cgacaaaacg atcgacacca atctttactt caccgatccg attattgtcg
    82741 ttcatacttc ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat atctttttgt
    82801 acatttccac gagcattcaa ataaacatca aacaatccgg gtgtacttgt ttcctttgca
    82861 tactttcgta tcgcatagtc tgcttgatta ccggttcctc catattcgat atacgaatgg
    82921 gtccgatcat taggatctcc attccaagaa tttataccat cccattgatt tgttccgttt
    82981 ttattgcctt gatgatcaag aacatttgta tttcctgtag gttgccaact ggctttagga
    83041 taagtgccct gatcatctgt tgtatattct gtaggaatcg tttgattaga tggcacactc
    83101 acagctggca aggataatgt aggcaatgta aatgggctga cagaattttc gttttctttt
    83161 gatgattctt cttctatttc gtctggcttt ggtactgaca catctgtatc tttcttattt
    83221 tctgtctcat caataatgtc atattcttta ttatcgacga tcagcttgtt tgcctggctg
    83281 tggtaaagtg ctggatcgat tggaaaactc agatcgatag tttgtttagt gtttgatgag
    83341 atttccaacg taattttccc gctatttacc tgataagcat agccatctcc ttcttttctt
    83401 tccacatcac ttaagtaatt ttcgactaga ccaatttctt tttctatctt ttcagcactg
    83461 gtgttattcg catttagctt gatgttcagt gctttttttc cagactgatc cgaaatgact
    83521 tcagctgaaa ttgtttctaa aactgttgga tcatctgtag tgtctgctat tgcagataat
    83581 ggcacaaagt ttgataaact caatattatc agcatgaaaa taactttcag tttcttccct
    83641 gtggtcgtca tttttcccct cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat
    83701 tattaaaata aacaggcgtt acataatttt atttatttta atatgataat tattatacga
    83761 agggcgctaa agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat
    83821 tccttcgatt aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc
    83881 aggttgttgg aaggaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct
    83941 gacaagtgga tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt
    84001 gtaaggtata tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca
    84061 caaaaattgg ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg
    84121 gaaatgtcgc aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt
    84181 aaaacgattg agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag
    84241 ttgaaacaat gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt
    84301 tttcagttaa ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt
    84361 ttaagttact acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa
    84421 attatggtca agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa
    84481 tctttcttta ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt
    84541 gaatggaaag ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta
    84601 atcttgaaaa atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat
    84661 tttgtcaata cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag
    84721 atacgaaaaa atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa
    84781 gaatatgttg ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat
    84841 acgactcatt tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata
    84901 cgtctatatg ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat
    84961 ctgatttatt atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac
    85021 cattatactt ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa
    85081 tatattgaag aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact
    85141 gctattactg aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg
    85201 aatcaaccca ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc
    85261 gcaaatgaag aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt
    85321 ataaaccacc ctgataaaaa tttcaggaca aatacacata gctgtttctt tttattgtat
    85381 tccttcagca atccaacgag atttatagcg aaagtctttt aacaactctt cttttgtcca
    85441 attatttgca atgagatccg tcaaagtgtt cattacgagg gtcatggaaa agtataggaa
    85501 actaactgct tcttccgacg attgaatgga gaaatgattg attcttaata attccagcca
    85561 tttttcgttc attggagaat cagccgatag ttctctacgt ttggttgtct gctgatcatt
    85621 tcgctgggtt aacaagtata acctttgcca atagatactt tcgtgatcta agtcgcagca
    85681 ccactctaaa tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt
    85741 taagatatct tgatggacta tgtgagaact gcttttgatc gtatacaaat aagcatcttc
    85801 caaatcttga aaatatttat aaaaagcacc gcgcgacatc cccatcttgt caacgatttc
    85861 tgagactttg acttggctga tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat
    85921 tctctgtttc tttgcgttcg ataaattgaa aaaagtttct tttggcatcc acatctctcc
    85981 tttatctctg attatacgtg gatagccctt cattgtcatg aaggattcat tccttctttt
    86041 tctcttcttc tgtcaagtac ccatcttcca ttcgataaac gcgatcactc cattgaatca
    86101 tacggacatc atgagtaacc ataatagtcg ctttttgttt ctcatgagct tctttaacta
    86161 gtaatttgac gacttcatat gcatgatctg tatccaaact agctgttggt tcgtctgcta
    86221 agatcaagct tggctcatta tataaagcgc gagcaattgc cactctctgt ctttctccac
    86281 cagaaaggtc tttaggataa ctatttttaa gtgactggat atctaaagat tgcagcaagg
    86341 aatcgatttt tgttgaatct tctttttttg aagtaacttg gtcaactagt tcaaattgtt
    86401 cctttaccgt taaaaaagga atcaaattag agctttggag aataaatcct atttctttaa
    86461 agcgtaaatc tgctcgtttt ttttctggaa gctcagttag tgagtgaccg ttgatcacta
    86521 tttctccgga agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta cttttacctg
    86581 aaccagaagg accaatgatg ctgacgaatt ctccttcctt tacataaaaa tcaattgctt
    86641 tcaaagctga gacctttgta tgaccagaac caaatgtttt ggtaactttt ttcatcgtta
    86701 atattttttt catttttatt aacctcctat tgctgtaatt gggtctactt tggttatcgt
    86761 acgtatcgaa aacaatccgc ctagcattgc gacaatgatc aaaatcccac tatatagcaa
    86821 ccattgtgac caaaaaacag caaaaggcat cgcgcttggt aaaatcagac tagtcaaata
    86881 agcaaacaaa agagcaagca gaacgcctac caccccaaca ataaaggact gtgctactaa
    86941 agatttagcg atgaagaaat ttttgatccc ttgtgctttc attactccaa aaatagcagt
    87001 cttctgaagt gtcatcacgt acatgaaaat accgaccacg gcagcaacca ctaagaacaa
    87061 aaagtatatc atcgcattta aggtcatatt ttgggcagaa tagccaggaa tactttcaat
    87121 gaatgtccca atagttaata actgtagacc cttcgatgct ttttctttcg aaattttagc
    87181 tgaatccttt attacgatcc cattgatcgg ctgttcttct tcagaagcaa acggctgttg
    87241 tccatacttc aaagcagtcc acgtatctag ggacgcatag atgacgggag aaactgtgta
    87301 ataagtttca ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc caattttgat
    87361 cgtatctcca attttatagc ctgaatcagc cagattttga gagatgatga tttcattctt
    87421 tgttttaaat tcatgccctt tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc
    87481 gaaaactgta acattttctt tgttttttcc tttgattgct ccgctgtaca atccgattgg
    87541 tgctttctct cctccttcaa tgtatttcag atctcctctt gttaattgtg aagctgcaaa
    87601 tacttgattt gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt
    87661 tttaaactct tctgaaagtc cattcgctag tcctgacaac atgaatacga catacgcaat
    87721 caagaacata ataccgacga tcaagccata tcgtaattta gaatagcgaa tttctttgat
    87781 agctagaaac atttgttttt cctccctatg atagattgat agtgacaaaa tgtcacttgt
    87841 tgaatagtgt aactctaaag tgacaatttg tcacttgtgt tgtttttttc ttatcaataa
    87901 attgtctaag acatctttcg ataaaacctt aacatgagtc ataaaaaatt tatttaagcc
    87961 ttatttatgc tttccatgat aaactaaagt gaccaaatca atgaggtggg aaaatgatta
    88021 aactattagt agtagaagac gataaagtat tatccaataa tataaaagaa atactcgctg
    88081 caatcggcga gataacacaa gtttatgatg gtagtgaagg actgttcgag ttggaaagtg
    88141 gagtttatga tcttgcaatc ttggatttga tgatgccgga aatgaatgga tatgaagtgt
    88201 tagcaaaaat acggaaagaa aaaatacaga ctccagtatt gattttgact gcaaaagata
    88261 gtttggaaga taagattgaa ggatttgaac gaggtgcaga tgattatcta acaaaacctt
    88321 tctatcgaga agaactgatc atgcgcgtga aagcattatt gaaacgctcg ctaggtctct
    88381 ttgatgaaaa tgttctgaag tataaggata tcagttgtga tttaaaaagc aatgaagtct
    88441 tgtataaaga acaagttttg cccatacaag gaaaagagtt tgaattgctc gtttattttt
    88501 tacaaaataa gggaatcatt ttgacaaaag agcagatatt tgaccggatc tggggatttg
    88561 attctgatac gacgattaca gttattgaag tttatatgag caacttacga aaacatctgc
    88621 gaagtactgg attggataaa gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa
    88681 gggtgtgatg caatgaatgg agatattaca cgaaagcaac gtagtcgctt ttttgcgaca
    88741 aatgtagcag catttgcttt tatctttttt cttttgggat tcattacttt acagatatta
    88801 aaccaatctg catacagaga aacagatctg tcattagaga aaataaattt tgattctcga
    88861 acagtacaat tagagataca aagatatcag caaggcgatc cctttttaaa cccgactcaa
    88921 acggaacaaa acagaacaaa catggaacag ccattaatgg aaccatcaaa tgaccgtttt
    88981 aacactcaag tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc agctattggt
    89041 gggcgtttca accaaatcaa agaattaaaa atggatacga aaaatctgaa taccatccaa
    89101 aatattgaat taaatgaaga cagtggctca tctgccctct ctttccgttc gattacgaaa
    89161 aaagcggaga cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa
    89221 atcaagaatt cattagcgac ttttcgcacg attatgattt tgtgtatgat tgttttttgg
    89281 attctctcta ttggtatcag ttattacttg tctagtctaa gcatgcgccc tattattctt
    89341 tcttggagaa gacaaaaaga atttgttgag aatgcttctc atgaattgcg cacaccgtta
    89401 acgattattc aaaatagttt ggaacatctt tttaccaagc ctaatcatac tattattgaa
    89461 gaatccgaaa gcatcgctca agcattgtca gagacgaggc gcctcactgg attgacttcg
    89521 gatttgctga caatcgctcg gaatgattct gatcagcagc tgctttcaaa gcaaatgatc
    89581 aatacacaag aatatatcga acaacttgtt aaaccatttc aagagatggc catcatagat
    89641 ggaaaagagt ttattctcca taacgatgca acattagaag taccaattga tgaaaaaaaa
    89701 atccatcaag ttttggttat tttgctggat aatgcattaa aatatacgaa tccagaagat
    89761 aagatcattt tggattcatc tgttaaccat aaagaatggc tgattcacgt aaagaatact
    89821 ggcccttcta tcagtgaaga agatcaagca aggatttttg atcgatttta tcgggaagat
    89881 caatctcggg cgaaagagac tggcggatac gggcttggct tggcaattgc aaaacaggta
    89941 atcgaacagc atcatggaca gatttctgta tccaattatc ttccacaagg agtcgatttt
    90001 aaagtccaat tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac
    90061 aaaaatcttg tcacagccct tttttgttgc gaataaacgg tgttccagaa gtagcttctt
    90121 cggaaataag ccgaaatttc tttaagctga ccacttctgt cacaacctct ttagcttacg
    90181 cttacgattt tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca atatccaatt
    90241 cttctcggct aacatcttct gtcacttttt caacatcttc atgttcttct ttatgaatcc
    90301 caacttcttc acgaataact gtatgtttgc ttacatctac ttgctcttct ttgattggga
    90361 tagtaatcgt gtcatcttcc aatttttcgt ctgttccctg tgaagattga tctgttactg
    90421 gtttgcgttc gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt
    90481 tgaccacatg tttgtggatg tcgacttctc cagttgtcac atcatgtgta tttacatcta
    90541 atttttcttc ttttagttga attgtatcat catctagatt tggtttgcga tcgatgtctt
    90601 cagtcttgct tgtacccatt gtatcagtct cgccaggtac gtccatcgga tcagttcctg
    90661 gtgtcatatt caatggatcc gttgtatttt gaaagcctgt cgtgccacct acgtccattg
    90721 gatctgttcc agtgccagtt tctaatccag tccccattgt gcttgctggg ctaacagtat
    90781 cttgtgtatc cattgtatct tctgttgttt ctggctgacg atagcctttt actgtgatga
    90841 caaattttcc atcagaaata tctcctctat attgatataa aggatcattt tctggtgtag
    90901 ccgtctcaga atcataggta tcaaaagaaa aagtatcttt tattttttcc cataaagaac
    90961 ggtcttcttc accatccatc cgattttcat ctgtttcaac atctatacca gacaatccgt
    91021 caaatcctag tctagatgct gcttcatcag tagtataaat aacgatatca tctcgttcat
    91081 acccttcgtt acgcaaccgt tcaattactg ataatgcttc ttccctcgta ctatagcttc
    91141 cgatgaccgt taaatttttc tcttccatgt aaattcctcc tagcaaatag atttatgatt
    91201 ggtatattgt tacttataaa tttattctat aggagacgat tgttttctac aaatatttag
    91261 attggaattt gattaaaaca atttaattga aatttgaaaa catttatgtt aatgaaagtc
    91321 atattctaat aaaatgtcat ttgtttctat atgaattttt atgaaaaatt tcatataatt
    91381 tccactcgtt gtgatggttt aatttatcca atccatcaat aagcaaacaa cttatataaa
    91441 aaaggattaa ttctcaatat aattgctcct accatagaat aaatcttcat gtaaagtaat
    91501 gaagtaccaa ctatttctaa tacttcttta agaattatcc caacaatatc gttagacaaa
    91561 ccattattga ataaatggag agccaatcga ttctgaaaaa atgttttcta atttttcgga
    91621 aataaaagaa agagcctcct gccattagaa cgaaccaaat ccatttcatt gctcatgaag
    91681 taaccacata gctaaaaaga ggataaatca attaaaagat caaaagaatg actgcactaa
    91741 taaaataact aaaaatgtat cttcttactt catatctttt agctagtact tagttaaaaa
    91801 tttgcttcct aagatcaaga caaactgtct atcttcattt gatgaaatgc ggtaaaatat
    91861 agaaaatgaa cactattgga gggaatttgt aatggacagc aaaactagaa aacaactgca
    91921 agaaaagtta aagcaacgta cacacttgct cccttccgtc tttcaacagt ttttagaaga
    91981 aaatcgttct tccctttcat taggcagtcg ctatgaatac gcaaaagatt ttcatctgtt
    92041 tactgattat ttgagaaaag tattttctga agaagtggat gatcagctga ttatccattt
    92101 agaaaaacaa gattatcaga atttcttagc taaaatctat cgacatactc gttcgttcca
    92161 aactacagcg aaccaagaaa cggagcaatt gtttgaaaat agctattacg ggatttcaag
    92221 gaagcaatat tcattaaatc attttttacg atttttgtat caaaaaggac tgattgaaga
    92281 agagatttct cttttgggta caagtttacc ggaaacaacc aaagcagctc cgcgatatat
    92341 cgatgcagaa cttttcaaag attttgagca tttgtttatc ccgattgaag gctttcaaac
    92401 aagcagagaa gctagctttg aagaaaagaa tagaccgagg aaccttgcaa ttactgccat
    92461 tcttctgtat tgcggattaa agatccatga agtagtagaa cttaaacgta aagatgtatc
    92521 tttgaccaag cagattctta atctgaatag aaaagaaaac agactgaata aagtaccaat
    92581 accaaaagaa gcgatgccat ttctggagaa ctattttaag ttaacagcac aaaatacgga
    92641 cgaaaattct tttgtttttc gttcctcaca tgatcagcaa atttctcctc ggactattcg
    92701 ccaaattttg agcaaaatta cagtatataa aaacgtatcg ccagaactat gcagaaaaac
    92761 atatcgttat tatgcagaac tatatttaga tgatgctgac gcggtaaatt atttatgtgg
    92821 taatcgatac ctctcatccc attcttttca agatatctgg gaaaagatgg ttgatttttc
    92881 ttatcacgaa ttagcggcat tcgttcgggt ttcttccata taaaacaaat gtatgatctt
    92941 tttttcacaa taaactatgt tattatataa aggattatgt tacgattatc ttgaatttgt
    93001 atattactta acaaaagata atggagtgtg aatgatggag accataacgt attccccttt
    93061 gaacttattt acgaattttc aagaagctgc agctaacttt tccgagaccc cgattatctt
    93121 tgatgagcca ctttcagctt tcccagaatt aggacttgaa acaacttaca aaaaatgctg
    93181 cgaaagtgtg ttgaaacggg cttatcaatt ggctcatctt ggagtgaaat ccggagacaa
    93241 agttattatt tataagagtt ccgcttttga cacatacctt ctagctgttt ctgtgtctta
    93301 ccttggtgca gtgcctgtca tgacttctta tcatctacca acaacaacaa tggaagtatt
    93361 tatcgatcgt ttagaagacc ctttcatttt atttgatgat gagacaaaaa agcgagtgag
    93421 agaaatttca aatggaacaa aatcaaaaca gattc
//
LOCUS       DACGLI010000003        91749 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.003, whole genome shotgun sequence.
ACCESSION   DACGLI010000003 DACGLI010000000
VERSION     DACGLI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 91749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.003"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            107..970
                     /locus_tag="IXT22_000201"
     CDS             107..970
                     /locus_tag="IXT22_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4861599.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1099..2721)
                     /locus_tag="IXT22_000202"
     CDS             complement(1099..2721)
                     /locus_tag="IXT22_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4861600.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2970..3491
                     /locus_tag="IXT22_000203"
     CDS             2970..3491
                     /locus_tag="IXT22_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861601.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3677..5407)
                     /gene="spxB"
                     /locus_tag="IXT22_000204"
     CDS             complement(3677..5407)
                     /gene="spxB"
                     /locus_tag="IXT22_000204"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAQ4861602.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5572..6390
                     /locus_tag="IXT22_000205"
     CDS             5572..6390
                     /locus_tag="IXT22_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAQ4861603.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6493..6690)
                     /locus_tag="IXT22_000206"
     CDS             complement(6493..6690)
                     /locus_tag="IXT22_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861604.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6859..7437
                     /locus_tag="IXT22_000207"
     CDS             6859..7437
                     /locus_tag="IXT22_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4861605.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8482..8985)
                     /locus_tag="IXT22_000208"
     CDS             complement(8482..8985)
                     /locus_tag="IXT22_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4861606.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9344..10369
                     /locus_tag="IXT22_000209"
     CDS             9344..10369
                     /locus_tag="IXT22_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4861607.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10692..11570
                     /locus_tag="IXT22_000210"
     CDS             10692..11570
                     /locus_tag="IXT22_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861608.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12046..12162
                     /locus_tag="IXT22_000211"
     CDS             12046..12162
                     /locus_tag="IXT22_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4861609.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13090..13428
                     /locus_tag="IXT22_000212"
     CDS             13090..13428
                     /locus_tag="IXT22_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861610.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13522..13752
                     /locus_tag="IXT22_000213"
     CDS             13522..13752
                     /locus_tag="IXT22_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861611.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14152..14523
                     /locus_tag="IXT22_000214"
     CDS             14152..14523
                     /locus_tag="IXT22_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4861612.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14797..15489)
                     /locus_tag="IXT22_000215"
     CDS             complement(14797..15489)
                     /locus_tag="IXT22_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4861613.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15492..16277)
                     /locus_tag="IXT22_000216"
     CDS             complement(15492..16277)
                     /locus_tag="IXT22_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4861614.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16514..17914
                     /gene="lacG"
                     /locus_tag="IXT22_000217"
     CDS             16514..17914
                     /gene="lacG"
                     /locus_tag="IXT22_000217"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4861615.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17939..18256
                     /locus_tag="IXT22_000218"
     CDS             17939..18256
                     /locus_tag="IXT22_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4861616.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18269..19942
                     /locus_tag="IXT22_000219"
     CDS             18269..19942
                     /locus_tag="IXT22_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4861617.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19956..21587
                     /locus_tag="IXT22_000220"
     CDS             19956..21587
                     /locus_tag="IXT22_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAQ4861618.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22078..23643)
                     /gene="guaA"
                     /locus_tag="IXT22_000221"
     CDS             complement(22078..23643)
                     /gene="guaA"
                     /locus_tag="IXT22_000221"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4861619.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23702..24625)
                     /locus_tag="IXT22_000222"
     CDS             complement(23702..24625)
                     /locus_tag="IXT22_000222"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAQ4861620.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24821..25426
                     /locus_tag="IXT22_000223"
     CDS             24821..25426
                     /locus_tag="IXT22_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4861621.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25734..26750
                     /locus_tag="IXT22_000224"
     CDS             25734..26750
                     /locus_tag="IXT22_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4861622.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26891..28192
                     /locus_tag="IXT22_000225"
     CDS             26891..28192
                     /locus_tag="IXT22_000225"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAQ4861623.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28238..28900
                     /gene="deoC"
                     /locus_tag="IXT22_000226"
     CDS             28238..28900
                     /gene="deoC"
                     /locus_tag="IXT22_000226"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAQ4861624.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28921..29319
                     /locus_tag="IXT22_000227"
     CDS             28921..29319
                     /locus_tag="IXT22_000227"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAQ4861625.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29385..30467
                     /locus_tag="IXT22_000228"
     CDS             29385..30467
                     /locus_tag="IXT22_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4861626.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30679..32241
                     /locus_tag="IXT22_000229"
     CDS             30679..32241
                     /locus_tag="IXT22_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861627.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32234..33367
                     /locus_tag="IXT22_000230"
     CDS             32234..33367
                     /locus_tag="IXT22_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861628.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33367..34323
                     /locus_tag="IXT22_000231"
     CDS             33367..34323
                     /locus_tag="IXT22_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861629.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34422..35588
                     /gene="deoB"
                     /locus_tag="IXT22_000232"
     CDS             34422..35588
                     /gene="deoB"
                     /locus_tag="IXT22_000232"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAQ4861630.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35612..36430
                     /locus_tag="IXT22_000233"
     CDS             35612..36430
                     /locus_tag="IXT22_000233"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4861631.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36447..37154
                     /gene="deoD"
                     /locus_tag="IXT22_000234"
     CDS             36447..37154
                     /gene="deoD"
                     /locus_tag="IXT22_000234"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4861632.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37452..38138)
                     /gene="gpmA"
                     /locus_tag="IXT22_000235"
     CDS             complement(37452..38138)
                     /gene="gpmA"
                     /locus_tag="IXT22_000235"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4861633.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38310..38891)
                     /locus_tag="IXT22_000236"
     CDS             complement(38310..38891)
                     /locus_tag="IXT22_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4861634.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39024..39707)
                     /gene="rpiA"
                     /locus_tag="IXT22_000237"
     CDS             complement(39024..39707)
                     /gene="rpiA"
                     /locus_tag="IXT22_000237"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAQ4861635.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40026..40439
                     /gene="rpsL"
                     /locus_tag="IXT22_000238"
     CDS             40026..40439
                     /gene="rpsL"
                     /locus_tag="IXT22_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAQ4861636.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40523..40993
                     /gene="rpsG"
                     /locus_tag="IXT22_000239"
     CDS             40523..40993
                     /gene="rpsG"
                     /locus_tag="IXT22_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAQ4861637.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41087..43174
                     /gene="fusA"
                     /locus_tag="IXT22_000240"
     CDS             41087..43174
                     /gene="fusA"
                     /locus_tag="IXT22_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4861638.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43346..44533
                     /gene="tuf"
                     /locus_tag="IXT22_000241"
     CDS             43346..44533
                     /gene="tuf"
                     /locus_tag="IXT22_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4861639.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44940..45248
                     /gene="rpsJ"
                     /locus_tag="IXT22_000242"
     CDS             44940..45248
                     /gene="rpsJ"
                     /locus_tag="IXT22_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAQ4861640.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45279..45908
                     /gene="rplC"
                     /locus_tag="IXT22_000243"
     CDS             45279..45908
                     /gene="rplC"
                     /locus_tag="IXT22_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAQ4861641.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45936..46559
                     /gene="rplD"
                     /locus_tag="IXT22_000244"
     CDS             45936..46559
                     /gene="rplD"
                     /locus_tag="IXT22_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAQ4861642.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46559..46849
                     /gene="rplW"
                     /locus_tag="IXT22_000245"
     CDS             46559..46849
                     /gene="rplW"
                     /locus_tag="IXT22_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAQ4861643.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46888..47721
                     /gene="rplB"
                     /locus_tag="IXT22_000246"
     CDS             46888..47721
                     /gene="rplB"
                     /locus_tag="IXT22_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAQ4861644.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47764..48042
                     /gene="rpsS"
                     /locus_tag="IXT22_000247"
     CDS             47764..48042
                     /gene="rpsS"
                     /locus_tag="IXT22_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAQ4861645.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48065..48412
                     /gene="rplV"
                     /locus_tag="IXT22_000248"
     CDS             48065..48412
                     /gene="rplV"
                     /locus_tag="IXT22_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAQ4861646.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48426..49082
                     /gene="rpsC"
                     /locus_tag="IXT22_000249"
     CDS             48426..49082
                     /gene="rpsC"
                     /locus_tag="IXT22_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAQ4861647.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49085..49519
                     /gene="rplP"
                     /locus_tag="IXT22_000250"
     CDS             49085..49519
                     /gene="rplP"
                     /locus_tag="IXT22_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAQ4861648.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49509..49697
                     /gene="rpmC"
                     /locus_tag="IXT22_000251"
     CDS             49509..49697
                     /gene="rpmC"
                     /locus_tag="IXT22_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAQ4861649.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49722..49988
                     /gene="rpsQ"
                     /locus_tag="IXT22_000252"
     CDS             49722..49988
                     /gene="rpsQ"
                     /locus_tag="IXT22_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAQ4861650.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50046..50414
                     /gene="rplN"
                     /locus_tag="IXT22_000253"
     CDS             50046..50414
                     /gene="rplN"
                     /locus_tag="IXT22_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAQ4861651.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50451..50759
                     /gene="rplX"
                     /locus_tag="IXT22_000254"
     CDS             50451..50759
                     /gene="rplX"
                     /locus_tag="IXT22_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAQ4861652.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50787..51326
                     /gene="rplE"
                     /locus_tag="IXT22_000255"
     CDS             50787..51326
                     /gene="rplE"
                     /locus_tag="IXT22_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAQ4861653.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51345..51530
                     /locus_tag="IXT22_000256"
     CDS             51345..51530
                     /locus_tag="IXT22_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAQ4861654.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51566..51964
                     /gene="rpsH"
                     /locus_tag="IXT22_000257"
     CDS             51566..51964
                     /gene="rpsH"
                     /locus_tag="IXT22_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAQ4861655.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            51996..52532
                     /gene="rplF"
                     /locus_tag="IXT22_000258"
     CDS             51996..52532
                     /gene="rplF"
                     /locus_tag="IXT22_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAQ4861656.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52693..53049
                     /gene="rplR"
                     /locus_tag="IXT22_000259"
     CDS             52693..53049
                     /gene="rplR"
                     /locus_tag="IXT22_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAQ4861657.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53070..53570
                     /gene="rpsE"
                     /locus_tag="IXT22_000260"
     CDS             53070..53570
                     /gene="rpsE"
                     /locus_tag="IXT22_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAQ4861658.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53585..53764
                     /gene="rpmD"
                     /locus_tag="IXT22_000261"
     CDS             53585..53764
                     /gene="rpmD"
                     /locus_tag="IXT22_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAQ4861659.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53808..54248
                     /gene="rplO"
                     /locus_tag="IXT22_000262"
     CDS             53808..54248
                     /gene="rplO"
                     /locus_tag="IXT22_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAQ4861660.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54248..55543
                     /gene="secY"
                     /locus_tag="IXT22_000263"
     CDS             54248..55543
                     /gene="secY"
                     /locus_tag="IXT22_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAQ4861661.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55605..56252
                     /locus_tag="IXT22_000264"
     CDS             55605..56252
                     /locus_tag="IXT22_000264"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAQ4861662.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56443..56661
                     /gene="infA"
                     /locus_tag="IXT22_000265"
     CDS             56443..56661
                     /gene="infA"
                     /locus_tag="IXT22_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAQ4861663.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56694..56810
                     /gene="rpmJ"
                     /locus_tag="IXT22_000266"
     CDS             56694..56810
                     /gene="rpmJ"
                     /locus_tag="IXT22_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAQ4861664.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56828..57193
                     /gene="rpsM"
                     /locus_tag="IXT22_000267"
     CDS             56828..57193
                     /gene="rpsM"
                     /locus_tag="IXT22_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAQ4861665.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57221..57610
                     /gene="rpsK"
                     /locus_tag="IXT22_000268"
     CDS             57221..57610
                     /gene="rpsK"
                     /locus_tag="IXT22_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAQ4861666.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57690..58628
                     /locus_tag="IXT22_000269"
     CDS             57690..58628
                     /locus_tag="IXT22_000269"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAQ4861667.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58656..59036
                     /gene="rplQ"
                     /locus_tag="IXT22_000270"
     CDS             58656..59036
                     /gene="rplQ"
                     /locus_tag="IXT22_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAQ4861668.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59308..60147
                     /locus_tag="IXT22_000271"
     CDS             59308..60147
                     /locus_tag="IXT22_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4861669.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60123..60992
                     /locus_tag="IXT22_000272"
     CDS             60123..60992
                     /locus_tag="IXT22_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4861670.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            60982..61779
                     /locus_tag="IXT22_000273"
     CDS             60982..61779
                     /locus_tag="IXT22_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4861671.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            61982..62728
                     /gene="truA"
                     /locus_tag="IXT22_000274"
     CDS             61982..62728
                     /gene="truA"
                     /locus_tag="IXT22_000274"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4861672.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(63183..65852)
                     /locus_tag="IXT22_000275"
     CDS             complement(63183..65852)
                     /locus_tag="IXT22_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4861673.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(66090..66278)
                     /locus_tag="IXT22_000276"
     CDS             complement(66090..66278)
                     /locus_tag="IXT22_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAQ4861674.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            66548..66910
                     /locus_tag="IXT22_000277"
     CDS             66548..66910
                     /locus_tag="IXT22_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4861675.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            66962..68644
                     /locus_tag="IXT22_000278"
     CDS             66962..68644
                     /locus_tag="IXT22_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAQ4861676.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            68761..70797
                     /gene="recG"
                     /locus_tag="IXT22_000279"
     CDS             68761..70797
                     /gene="recG"
                     /locus_tag="IXT22_000279"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAQ4861677.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            70846..71847
                     /gene="plsX"
                     /locus_tag="IXT22_000280"
     CDS             70846..71847
                     /gene="plsX"
                     /locus_tag="IXT22_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAQ4861678.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            71969..72211
                     /gene="acpP"
                     /locus_tag="IXT22_000281"
     CDS             71969..72211
                     /gene="acpP"
                     /locus_tag="IXT22_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4861679.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            72479..73483
                     /locus_tag="IXT22_000282"
     CDS             72479..73483
                     /locus_tag="IXT22_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861680.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            73484..74428
                     /locus_tag="IXT22_000283"
     CDS             73484..74428
                     /locus_tag="IXT22_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861681.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            74428..75390
                     /locus_tag="IXT22_000284"
     CDS             74428..75390
                     /locus_tag="IXT22_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861682.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            75417..76331
                     /locus_tag="IXT22_000285"
     CDS             75417..76331
                     /locus_tag="IXT22_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861683.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            76357..78138
                     /locus_tag="IXT22_000286"
     CDS             76357..78138
                     /locus_tag="IXT22_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4861684.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            78486..79172
                     /locus_tag="IXT22_000287"
     CDS             78486..79172
                     /locus_tag="IXT22_000287"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4861685.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            79192..82773
                     /gene="smc"
                     /locus_tag="IXT22_000288"
     CDS             79192..82773
                     /gene="smc"
                     /locus_tag="IXT22_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAQ4861686.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            82782..83591
                     /locus_tag="IXT22_000289"
     CDS             82782..83591
                     /locus_tag="IXT22_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4861687.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            83602..84600
                     /gene="ftsY"
                     /locus_tag="IXT22_000290"
     CDS             83602..84600
                     /gene="ftsY"
                     /locus_tag="IXT22_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAQ4861688.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            84787..87054
                     /gene="gshAB"
                     /locus_tag="IXT22_000291"
     CDS             84787..87054
                     /gene="gshAB"
                     /locus_tag="IXT22_000291"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAQ4861689.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(87143..87595)
                     /locus_tag="IXT22_000292"
     CDS             complement(87143..87595)
                     /locus_tag="IXT22_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAQ4861690.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            87745..88695
                     /locus_tag="IXT22_000293"
     CDS             87745..88695
                     /locus_tag="IXT22_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4861691.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            88688..89647
                     /locus_tag="IXT22_000294"
     CDS             88688..89647
                     /locus_tag="IXT22_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4861692.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            89644..90399
                     /locus_tag="IXT22_000295"
     CDS             89644..90399
                     /locus_tag="IXT22_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4861693.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            90422..91375
                     /locus_tag="IXT22_000296"
     CDS             90422..91375
                     /locus_tag="IXT22_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4861694.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
BASE COUNT        29493 a        16376 c        19626 g        26254 t
ORIGIN      
        1 ttttgattag aacttgcgaa aataaaccgg ttaaagtgtg tctagcgcaa gagatttgct
       61 ataatagacg ataagggtaa aatgtaacga gaaggggttg aaaaatgtgt atcaaattgt
      121 aacagattct tgttgtgatc tgccatacca tgtattagca aaagaaaaag ttgatttttt
      181 atcaatgaat ctccaattga atgatcaaga gttagtagat gacctcggaa agacattcaa
      241 ttatgaccgc tacatgaatc agctgaaaaa tggtgcgatg cctacgacat cacaaatcaa
      301 tgttggccga tatttagaat ttttccgttc ttatgcggaa aaacagattc ctgttttata
      361 tgtggctttt tccagtggat taagcggctc ttacagtagt gcgcttcaag cggttgaatt
      421 gctgaaggaa gaatatgaag accctgagat ctatgttttt gatacaaaag ctgcaagtat
      481 tggggaaggg cttttagtat tggaagctgt aagattgaaa aaagaaggta aaagcatcga
      541 agaaacccta gagtggctgg aaagtaatta tttgaaagtc cattcatggg taacagtaga
      601 cgatctgaaa tatctagaac gaggcggtag gatttccaaa gcaagtgcta ctcttggcag
      661 tctattgagt gtaaagccta ttattacggt ggataaagaa ggaaggctga cgaatgttga
      721 caaagttcga ggaagaaaca agtcgatcca gacaatcgtc aatgagacgg taaaaacaat
      781 cgttgcacca cttgatcaaa tcgtttatgt ggcttacgct ggggatctag agagcgcgga
      841 gaaggcaaaa cggcttttgg aagagcagat aaagatgaaa gatgtgaagc tttatccctt
      901 aggaccaacg atcgccagtc acacaggcta tggctgtatc gcgatttttt cgatgggaat
      961 cagtcgataa aagcagtaac tcattctgta aaaaagccca gaaattgatt gtaacaaaaa
     1021 cagcgactct taaaagatag atgagcatcc tatctcttag aggtcgctgt ttttttattt
     1081 tttaagctaa ataggccatt atgcccataa ctcgttcaat tgtttttgaa tatctgcatt
     1141 ttccaaaaat tcatcatatg tcgtatcagc tcgatcgatc acacctttat ccgaaacggc
     1201 aatgatgcgg tttgccaatg tttggataaa ttgatggtca tgtgacgcaa ataagattga
     1261 gccagtaaat gccatcaagc cgtcattcaa tgctgtgatt gattctaagt ctaaatggtt
     1321 cgttggatca tctaatacaa gtacgttagc tttcgaaagc atcatttttg aaagcatgca
     1381 acggactttc tctccaccag ataaaacatt cactggtttc aatacttctt caccagaaaa
     1441 caacattctt cctaagaagc ttcttaagaa ggtgttatca tcttcttctt tacttgcata
     1501 ttgacgcaac cagtctaaaa tcgttagatc agtatcgaat tctttcgttg tatcctttgg
     1561 taaataagaa ttacttgttg tcacacccca acgtactgtt ccagtatctg gcgtaatttc
     1621 acccatgata actttgaata gcgttgttgt tgttatatca ttttctgcga cgaaagcgac
     1681 cttgtcttct ttgctcaaat taaaagatat atcatctaaa attttctttc catcaatcgt
     1741 tacacttaca ttttctacct gcaataagtc gtttccaatc tcacgttcag gtttgaatcc
     1801 aacgaatgga taacgtctag aagaaggttg gatatcgtct aaagtaattt tttcaagcat
     1861 ttttttacgt gaagttgctt gttttgattt tgatgcattc gcactaaagc gggcaataaa
     1921 ttcttggagt tctttgattt gttcttcttt tttggcattt gcgtttgctt gaagtttagc
     1981 cgctagttga ctagattcca accaaaaatc ataatttcct acataaagtt tgattttacc
     2041 aaaatctaga tccgccatat gtgtacatac tttgttcaaa aagtgacggt catgggatac
     2101 aacgatcaca gtattttcaa aattgatcaa aaattcttcc agccaattga tcgattggat
     2161 atccagaccg tttgttggtt cgtctagcaa aagaacatca ggtttaccaa atagtgtttg
     2221 tgctaataac acttttacct tttgtccacc agttaattca ctcatttgct gatggtgcaa
     2281 ttcttcaggg atgttcagac cttgcagtaa aacagctgct tctggttcag cttcccatcc
     2341 attaagctca gcaaattctc cttctaattc agctgctcga ataccatctt cgtcagtgaa
     2401 atcctctttc atgtaaatcg catctttttc tttcagcact tcatacagac gcttgtgtcc
     2461 catgatgact gtttcaagta cagtatagtc ttcatagtcg taatggttct gtttcaatac
     2521 ggccatccgt tcatctggtc ccatagtaac ggaacctgtg gaaggctgca gatcccctga
     2581 taacacttta aggaacgttg atttacctgc accatttgca ccaatcaagc catagcagtt
     2641 tccgggggta aatttaatat tcacatcatc aaatagtttg cggtctgaaa agtgcaaact
     2701 cacatcattt acagtaatca atttttttcc tcacttttat cattattagt tttgacaagt
     2761 cttatagaat tatatagggg aaaggtaaaa gattcaaggc aatcgaacat tctttgtgtt
     2821 tcacgtgaaa cagaatgaaa aaaataaaaa taaaagcgga gcgaaaatag ctactatagg
     2881 atttattagt ttgcaacagc ataatttttg acgttattta taagagggag tactataaaa
     2941 ctgtaaaaga aatgaaagaa ggattgaaaa tggatgaaaa aagaaccatc gactggggct
     3001 cattgatttt gggaatttta tttgtacttg tctcattgtt atcatttcaa gaccctgtcg
     3061 gaaatttagt tgcaattgta gtagtctttg cgatttttgc ctttattaaa gggatatttg
     3121 aactgtttgt acggaacaga ttaaaagagc taacaggata taaaggaaag atgcccttaa
     3181 taatcgggat catcgatatt ctagttggcg tctttttctt attcaatatt ggtgcaggag
     3241 tcgcagcatt gccttttgtt tttgcagtat ggtttattgc tgattcagtt ttagcgttat
     3301 ttactgctga cttggcaaga ggagtaagtg aaggatatta ttggtttacg atcatcgtca
     3361 atattttagg aattttatta ggaattttct tattgtttaa tccaatttct tctgcgttga
     3421 cattaagctt tttagttgga ttctatttta tgttatttgg tatcacacat atcgtctatg
     3481 catttagata agtaaaatca aacaaataaa aaagccggct tccgattaca gttttactgt
     3541 tgtaattgga agccggcttt tttatcatgg acaaatatgc acgaggtgat ttttaggtgt
     3601 cgagacaaat ttatgcaaaa atgtgagaag ctatatacac aaattttatc ttaatactcg
     3661 aagcatagcg cagttgtcac aacctctttt catataattc attcaatact ggcaaatcat
     3721 ggacttcata tttttctttg aatgcttgga tttcttcttc agaatatttt cttggatcta
     3781 aatgcagatc ttctactggc aatgggcgct tgttattgat cttcacatcg attactacag
     3841 gacgatctga ttttgcagct gcatcaaagg caaatcgaag ttgcgagtat tctgtgactg
     3901 taaagctatt tgccccgagc gcttctccaa ctttaccgaa atctgcatct tctaaaaata
     3961 caccaaattt cttttgttcc gtatcttctt gttctgcttc gatgaaacca aaagaatcat
     4021 tcgaaaagac aacattaata attggaagct gatatttgac ttgtgtaatg atatcttgca
     4081 tgaccatagc aaacccgcca tcaccactta aggtaaatac ttgtttttct gggtagctta
     4141 gttgtgcggc aattcctcct ggcacaccat tacccatagt tgcgaaccat ccagatgtcg
     4201 tatgtttttg tttaccgttc atattcaata aacgaataga atggatagtc gtgttaccga
     4261 catctgtgac gaaaatcgca tcgtcttcag caatacgatt gatttcttta tagacagcct
     4321 ctggacgaat cggttcttcc tctcgatctt caaaagattt caaccaattt acccattttt
     4381 ctttattttc ttgatttgct aggtaccagc tatcagcagg gcgagcatcc cctaactcga
     4441 caagtctttg caaagctgtg tttgcatcac cgaggatcga caaagatgtt tcatggcgtc
     4501 gtccaaattt tgacgcatcg atatcgattt ggataaattc agcagttgga ttaaaaaatg
     4561 cacgtccaaa tgggaagtcg ctaccgacaa ataagatcag atcggcttct gccaatgctt
     4621 catttccggg tttagtagcg acacgtccag caaaaccaag aaagttttca taatcatcag
     4681 gaataattcc ttttgctaga acggaagcga caacaggaac tgaaaaatgt tctgagaatt
     4741 ctttgatttg cggaaatccg tttcgcgttc cttgaccaac ataaagaact ggtttttttg
     4801 ctttttcaag ataaggcaaa gcagctagca aatctttttc ttctggtaat atcacacttg
     4861 ttttgtgagt gtgagcggtg gagaaaggtt gttcgtcaat ttcttcaaaa ccaagatcaa
     4921 cagggatagt cacgatagcc acgcctttat gctcataggc ggctttaatg gcttcatcta
     4981 ctacatgcgg aagactttgt ggtgtcatga ctgtacgatt gtatacgcta acatctgcga
     5041 aaataggatt ttcatttagt tcctggaaag agttatagtt catggatgta gaagcaactt
     5101 gtcctaagaa cgctactaga ggcacatggt ccatctgtgc atcatacaaa ccattgatca
     5161 aatgtgtcgc accaggtcct gcagagccga agacagcgcc gactttcccc gttaattttg
     5221 catctgcagc ggctgcgagt gcgccgactt cttcatgacg aacttgaatg tagttgattt
     5281 cggttttttc ttgatatagc gcatccataa ttgaattgaa agatcctccg ggaatgccgt
     5341 aaatatggtc gataccccag ctttcaagaa cttttaccat tgcgattcct gcattgattt
     5401 ttgacatggt gtttcactcc tttagcaatg atgatacata aattttttgt atctagagta
     5461 tagaactttt tatcgaaaat cccaactaat tcgtcttttc acaaaaatgt agtcatgttt
     5521 ttgggaatat gctagagtag tacatagata gattcaagag aggggaatgg catggttgaa
     5581 tggctattga gacttgaacc ttggcagcaa gcacttgctg ggacagcttt tacttatttt
     5641 atgacagctc ttggtgccgg gttggttttt ttctttaaag aaatcaaaaa agaagtgcta
     5701 aacttgatgt taggatttgc ttctggtgtc atgattgctg caagtttttg gtctttgtta
     5761 gatccggcta ttacaaaagc agaagaaaat ggagatattg cttggctagt tgtaagtatt
     5821 gggtttggtt taggcggtgt gtttttatat atggcagata aaacactgcc ccatatgcat
     5881 tttggaccac aacatgaagc agaaggattg cctacccatt taaaacggac gatcttgctt
     5941 gttttttcta ttacattgca taacattcct gaaggtttag ccgtgggggt agcattcggt
     6001 gcagcagcaa ctgcggataa tccgacagcc gctatattag ccgctgtttc ggtggcgcta
     6061 ggtattggta tccaaaactt cccagaagga gcagctgtat caatcccgtt gcgacaagaa
     6121 ggtctgagtc gtaaaaaggc ctttgtttac ggacaagctt ctggaatcgt tgaaccaatt
     6181 gctggagtga ttggagcgct actagtaacg aaagtggagc tgctgcttcc ttatgcactt
     6241 gcttttgccg caggagcaat gatttatgtc gtggtggaag aattgatccc tgaagcacag
     6301 cagacattgt ccagcaaacg tcattttgca gtttttggcg tcatgagtgg atttatcatt
     6361 atgatgattt tggatgtggc attaggataa ataaaaaaaa tatatatgat atatcaaata
     6421 gggccgcgaa cttatatcgc gaccctattt ttttagtaag ttatatcata atgaagtgaa
     6481 tggtatcata cattaataat agttttttct atgtgtattt cctttgatcc agcgaacaag
     6541 ccagatgata agtgcgattg ggattagaac tttgaccgca aaccataaaa gcccgcttag
     6601 gacactgaca aaaagactga tgacgaagct agctgcaatt agcactaaaa gaaccatgaa
     6661 gatatttaag aacatatttt tttgacgcat acaaaaccct cctcttgttc attctttact
     6721 atagaaaaag tataacaggg attgtttaaa aacacctcca actgaagact gatttttact
     6781 tcatctactt aaatgatcaa acaattgctt tttctctggt ttatcatcta aaatagagcg
     6841 gaaaaggagg agaatatcat gcctaaaaat cgtcttgaag catttacaga tgctgtaatc
     6901 gcgattatca tgactatttt agttttagaa cttcatgaac ctaacggaga cacgtgggag
     6961 gcgctcgctg cattaggtta ccgatttttt atctatattg tcagttttat cattttagcg
     7021 atttattgga acaatcatca tcatttattt caagttgtac ataagataaa tggacgggtc
     7081 ttatgggcga acagtttctt tgtttttgcg ctttcgcttt ttccgtttgc aacttcatgg
     7141 atcagtgagt acatcaatag cctggctcca gaaatgactt atggttttgt taccttgacc
     7201 gctaatattg cgtattatat cttggcaaaa gaacttgtca aagcaaataa aggccacgag
     7261 aaagcattga aggcgatgtt gaataattac aagaaatcgt atctatcgat tggtttgaat
     7321 gtgttaggaa ttgtcttagg gtatttagta gcgccagtag ccgtgctgat cgcaaacatc
     7381 gtgattctag ctgcttggat catcccaagt cgtaccatcg aatcacaata tcggtaaaat
     7441 gatccgtgtt taaaatttaa gagaaaaata tagaaaaaat aaataaacga tcaaatatcc
     7501 gagtgatact agtattcaaa gagggatgca gatggatcaa aaaagaattc atgtaggact
     7561 gattactagt tttgtcacga tgcttattta tttggatcaa ggtcatttga cttggacagt
     7621 agttggtgtc gtaggatttt tgacattatt cacagcaata aaaaaataaa catctttatg
     7681 taatctgatg ttctatctat ttaagaaaag catgtttaca gcagtatgat tctgttgtaa
     7741 acgtgttttt atttgtggaa aatttaattt ttagaaaagt gtatcgaaaa atagatagtt
     7801 agtttttcca cagtggataa cttcgtaaga gataaaaata aaaaattagt caaagaaggg
     7861 cgtatagatt tcttttgata ggagatatac aacagaaatg aataaatatt aacgtgtttt
     7921 caaacagtat aaaacggtgt ggtttttgga ataaaaaaat aacatatctc attttacact
     7981 tttgttattt tatacttaaa aaataacgac acagaaaata ccgtgtctca gatttctcta
     8041 ctacttctaa aaactactgt ttttttcctt tgaaatgcct tcaaaaagta ggatcaggca
     8101 gaatatactg gcagaatcaa ggagaaggga gcctaaataa ggagaaaaac catagaaaat
     8161 ataaagtaat tacttataaa acaagctttt tatagaaaaa taatatacct gagtagggta
     8221 taaattaaga cggaattcct ttctagattg agatattgac taggaagaat gttaagattt
     8281 taagccttta agctaaaaaa aaaccctttt tgttaaataa ggggaatata gcctgtcagt
     8341 ttcaaactgc aagtcgtcct gctgcaataa tatagtagat tagagatgaa aatagatttt
     8401 tttaaaccaa tgactgaata aaaagaccgt catagataca cattggaatg tgtctattac
     8461 ggtctttttt tacgaacgat tttattgaag acggacagtt cgggtcaaaa ataaaaaagc
     8521 tacgatcaga aataagaata aaatgtatcc caaaataatg gctagacggt ctaacttatt
     8581 tgtcgataga tgtttgttta gaagttgata ggcccataaa cctatcagtc ctcctgttgt
     8641 attagttatc aaatcagtga tgtccgctac gccaataccg aataggaatt gaatcaattc
     8701 tgccaagaag cttacaagga aaataatccc taatttttta gaaaaagaaa gtctcttgaa
     8761 attgacattc aaaagcaccc caaaaggaaa aaagacaatc aagttataag tggtctcacg
     8821 taataccgtc gtattttcaa aagaaaaagt agaaaaaggg acgagattga cattgctgta
     8881 agaataagtg agaaattgtg gaagattaaa tgatagcttg aataaaatca accataatag
     8941 aaagaataaa taaatcccta ataaaaattt tgatacatac cgcatagaca tctcctccat
     9001 ttaaaaagta taccatcgaa aaccgctgaa aaatcataaa aaagtatgaa gtttaaggac
     9061 caacgtagtt atcgtacgaa aattagaagc ttttttttgt tgggaatccg gtttctttaa
     9121 caaagctaag atagcgagtt gcttggaaaa gttgctatct tttttctgtc aaaacgactc
     9181 ggaatgttcg ttttttgttc taatttctcc aagttgttta ctttttgata ctaagtttat
     9241 gaaaaatcaa gaaatagttg ttatactagg taatgctgac aaacgggatt ggcatttcat
     9301 cttggttcag ctttttttcc aattactagg aaggagggat agattgttca agacttattt
     9361 tcgtttcaat aaaatacaag ataatccttt tcgtatcatg aatctgatgc tacttatctt
     9421 tattgtatta tggttaggtt acataaatca tgattttttg atttcaagtt tttcatcatt
     9481 agggatcttt acttttttct attatcaaaa cataccgatg aaatatttgc tgaaacgtat
     9541 gtttctgatc ggttgcggac tgttggttgc tttcgttttg gggatcttat cgacttatgt
     9601 tttatggctt gaaccatttg ccgtagcttt ggttgctttt tccagcagat tcgtgttgcg
     9661 attattccat atttctaaac caggtggctt gttttttgcg atgctttctg ccatgggaac
     9721 gagcatgcag ctgccaatcg ctcaattacc gatcgtctca ctttattttt ttatgggtgt
     9781 cgtttttgcc ctgattgcgg cagtgattac aaaattactg gattcacggc ctgagcagac
     9841 aattgaaaaa gcaactttaa aagaaagatt tcacgaagag cctttagtga tcattgattc
     9901 tgttttctac agcgctgcct tatttctttc cgtttatgtc agtcacggct tgaatctgca
     9961 taatccttat tggttgacct tgtcatgtgc atcgattttg ctagcagaaa acttggatgc
    10021 gatgaagcat cgacaagtcc aatatctgat tggatcgatg ggtgggttat gtgtgtcggc
    10081 attcttgtca tttgtgccgt ttacgcagtt gcagaccatt tttctgatca cttttctata
    10141 tggaatcgca caatttctag ttgctagaaa ttatgcagtt gctaatattt ttcttaatcc
    10201 gatggcgttg atgctatcta cacttattcg tggagcatac ttgatttctt tgatcgaata
    10261 tcgtttttta gggatcgtca taggaagttt catcggttta ggtgttgcgt gggtaatgac
    10321 ggttggtttg caacattatt taacggttgt tcgtcaaaaa ttagaataga aggacaaata
    10381 tatgtgccaa aagaggttat gacaagattt ttgtcacaac ctctaattca aggtgttcaa
    10441 aagccagatt ctcagcatta agtcaaattc acacaaaaat gtggaaagga actttcaaaa
    10501 aaattttata tttattctat caaaaaattt tgtttatgat ggtaactgaa taaactttcc
    10561 tgagatggtc aatgctttcc ttgaaagtct tacagatatt ctttcttcat agaaagttta
    10621 agttttatag ttagtgtaca ataaaagtat gtttatacca tatggtgtcc ggataatcag
    10681 tcatttaaac aatgaggttc aaagatatga aaaggggaaa tttgatgaag aaaataagca
    10741 atgaaatcca aattctggca gaaactttaa ctcttcccaa agtcgttata gagcaaatga
    10801 ttgtacaagc aaaaaacatc cttgatgagg tgtttgagca atatagtcat gaactaatgg
    10861 atcctaataa agcaaaggcg actgcaaaga aaatagacaa agtctatgaa gaggaacctt
    10921 ttgcagcatt agctatttat ctatatgcag cttctcaaag ttggaaaaaa atttatcaac
    10981 cattgaagat tccaagaact atctatttgg caacaatgaa tgcttttact agatttattc
    11041 atgaacattt ccaagtaaca ggaagctatc gctttgaccg tggtttttgg atttggcatt
    11101 acactagtgg cttgatcttt cggattggtg aattggagta cgaaatgaca tattttccga
    11161 aagggtacac ggatctaaga ttagaaggaa agcagtgcct ttctcttcat attccttccg
    11221 atgcagattt atctcagaat aagataagag atagttacga aagtgccatt cgtttttttg
    11281 aactttattt tcctgattac cattaccaag tgatgtacac agatacttgg ttactatcac
    11341 ccaatcttac taaatggttg aaaaaagagt caaaaatctg tctttttgca gccgattatc
    11401 gattattatc agttgatgaa caggacgata gtggagtccc ttggatcttt ggacgagtag
    11461 atgcccaaat acatgattat ccagaaagta cgagtttaca gcgacaagca aaagagcaat
    11521 tgcttgcagg cgagcacatt ggctctggct taggtattct tacttcataa gtttagtact
    11581 tcgaaatagt ttaaaagagc gtgagacaaa agtaaagaac acttttgtct cacgctctaa
    11641 acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    11701 atttgaaaag caattttcgt gaatttcttc ttgtttcttg gagttaaacg cttctgtccc
    11761 agcctctttt ttagtgttct atcgaacaca cagtacgttc aataggtaaa ctagctataa
    11821 caatagatat taaagttaac ggacaagagg gcctttttta ggtagctaaa acgtaataat
    11881 gaaaatttat ttccagagat aggagtcaat cagctagtct gatcgactgt tttaacaagt
    11941 tgactttcat tttaactttt gataccattt aaaacacaaa tcgtaattgt ttcgatttgt
    12001 gttttttagc atgactacaa tcaaagaaga aagtgggtcg tccatatgga aaaaacagat
    12061 atctcaagtg cataccgccg cttgaaaagc ccaaatatca aaacacgaaa acgtgcgctg
    12121 aagatcatca aagatgtgaa acggaatagt gggaaaaggt aagaagaagg aaacttaatt
    12181 aaaaaaatag ccgaaaaacg tttttcggct attttcaata atcggttttt gtgtaaggtt
    12241 tccgaaagaa ctgctgttga ttttccattt ttaacatatg ataaattggt agaatctttc
    12301 ttttcaaatt gataccattc cctaattcca gttatatagt taactacaga accacaaagc
    12361 acgtacgttt ataaaagtat tatctgtagt tatttttcaa ttccctttca acctcttatt
    12421 ttgaccagta gtattgatca ctttaccttt taacaccttt gttcgttttt gaaacatttt
    12481 tagtcaagaa tggaaacgta actacataat caaaggtttt gcgaaatatt tcatgaaata
    12541 tttcatgtag aagcgagcaa tacggttgca aataaccatt atcgtttaat aagcagttac
    12601 gaaagctccc aatatctcta acgttcagct cactccattt cttttcttca aaaaaatcag
    12661 tgattcgtat ctctttctat ttgtcgaaaa agttaacttt aaaaagtaac gccgaaaaaa
    12721 tatgcaaaaa aataaaaaag cagttactat tgctagaata acatcaagga ataataagtt
    12781 ttggttttca gataatagtc gataagttgt gtattggaat tttagataca gtaataaagt
    12841 atttttcatg aaattttgtg agaatcacta ttacaagtat ctttaataaa attaatggtt
    12901 aaggaggaac ttaaagtaga atgtaaatga atagttgtag tcagtcgatt gtgatactag
    12961 actcaaagtt gcaggaataa gtttttcaat ttgtgattgg aagataaaaa atgaaaaaga
    13021 agggcttttt tttatacttt gttgattgta gtgtttattt tccctctgtt tagccaagta
    13081 acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt tcgtgctaca
    13141 gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc tagtgagcca
    13201 attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt tatggtggta
    13261 aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat tgaaaaggtg
    13321 agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat cattttaacg
    13381 gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac actagtgaaa
    13441 tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa atcgatcatc
    13501 aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat ttattacgtg
    13561 aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag tcgctactca
    13621 attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa aactgttttt
    13681 tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga ttatgttagt
    13741 atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg ttattgtttt
    13801 ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt atccagagta
    13861 ttttatttta acttttgtat atttagtaag tagctacaca cttctatata aattcagaag
    13921 ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat aatatttttg
    13981 atttatatag gaaattaaaa atattataga atcaacactc agagaacggg ttggttttta
    14041 atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga agttggttac
    14101 cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat aatgagagat
    14161 tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa tgaattatct
    14221 gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga ctatattgat
    14281 atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat aaaagctttt
    14341 atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct agtaggaaaa
    14401 ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc tttgtctatg
    14461 ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt ggaaatcttt
    14521 taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga tgatttttaa
    14581 gattggtttg agaaataatg tgaaaacact atttttaatg ttaattatag atagagatga
    14641 acgcgtcata tggttaaaag aatgaaaaag tcaaagatac actgctatat ttcactaagg
    14701 atatagcagt gtatctttca tgtcgtttca ctggcagttt tttataaaag gaggtgtgca
    14761 tttcagttgc ttttctttgg tagttagttg aatcgtttaa gaattaacgg atgtggcaga
    14821 caggtgctct gtccaaaaac cagtaaaatc tttgatggtt ccatctttat ttagctgtgc
    14881 ctgttcaaat actgttttgt ttttaccgaa tggatcaatt gcaataattg ttccgatccc
    14941 cgcacgtttg gcagcaagta atcctgagta agcatcttcg ataacaagac aatcagccgg
    15001 agctaagctc agtttgtctg ccgctttaag aaaaatatcc ggttgcggtt tcccagggaa
    15061 agagccgtcg tcatagacaa tcttgtccca gtcaaaccag cgggctaaat cgaaaatatc
    15121 aaaataaaaa gcaacattct ctttgacagt agccgtggca atcgttaatg gaatctgttg
    15181 gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc aactgaagct cgttttcatt
    15241 ttgcaagcaa agcatacgat aatagctttc tttttcttct gacaatacgg cgatctcaga
    15301 ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc gtattcgtcc gaccatgaat
    15361 attttttaaa atatcctcgt ctgataaacc atcttttgta tgatcatgta tcatatgcag
    15421 ccaagcagct tcatgcagat gagagtccaa aaacattgtt ccgttgaaat caaatataat
    15481 ccctttcata gttacgctcc tatagtggta ttttcggttg aatcagcaat ttgcagatcg
    15541 acatattgtg catagtgctc ttgaacctcc cgcgagatct ggcgatccgt aatgagcaga
    15601 tcgaaatcat gcaaattata aaacacataa aaatcatctc gattgaattt tttattatca
    15661 acgagtagat atttcttacg ggaattattt agagcgatct gctgtgcttc tccttcttcg
    15721 gtactgtaag tagagatcgc ttcgttgtga acgccatttg aactgataaa tgcttttgta
    15781 aactttagtc ttcttaaatt gtcgttggtg atcggtccga caaatgcgcc ggtatttttc
    15841 cggaaatcac cgccaatcag tagaatttct ggtccatctg cttgagcaag aatatcaaaa
    15901 actggataat tatttgtaat gatccgaatt ttcttgttca gtaaatgcgt cgccaatagt
    15961 tcgattgttg tacctggtcc taagaaaatc gtttctccct cgtgaatcaa ggaggctgct
    16021 gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg ctttttcagt gtgagaaagt
    16081 tcttgatcta aagtgtagga aagactttga gcccctccat ggacacgcag cagcttgccc
    16141 gatttttcta attcatctaa atctctgcga acggtcatat cagaaacatc taattgattg
    16201 atgatttcat taacggtaag gattcctttt ttattgacca tttctacgat agtaagcaat
    16261 ctttcttttt tcaacattgt cttcacctct aatttaagga taatctatca tataaacgga
    16321 caacagtcaa tctaattcga acaaaagtaa acatttaggg tggtttttat gtttgttaca
    16381 atagatttta ttgctgtttt ctggttttta tgattatttg tgtttgtttt tgttgacaaa
    16441 tgttttggat gcgtttacaa tgcaatcagt tagaaagagc gaaaactgat tatagatttg
    16501 aggagagatg tacatgctta aattaccaga agattttatt tttggcggag ccacagcagc
    16561 ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc gctgttgctt gggatgactt
    16621 tttagaggaa caagggcgat tcagtcccga tccggcaagt gatttttatc atcaatatgc
    16681 aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt ctaagattat ccattgcttg
    16741 gagccgcatt tttcctgatg gagctgggaa accaaatcca gaaggaatcg ctttttatca
    16801 tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg tttgtgacgt tgcatcattt
    16861 tgatacccct aaacgtttgt ttgaccatgg agattttttg aatcgagaaa caatagaagc
    16921 atttgtttcc tatgccattt tttgttttca tgaattcaaa gaagtcaagg tgtggagtac
    16981 ctttaatgaa atctatccag ttgcaaccaa tcaatatttg ttaggtgttt tcccaccagg
    17041 aatcaaatat gattttacaa agatcgtcgc ctgtcttcat aatatgatgg ttgctcatgc
    17101 ccgtgtagtg aactatttca aagaaaacga acttccgggt gaaattggtg tagttcactc
    17161 attagagacg aaatatgcgg caacagacgc gccggaagat aagcatgctg cctttttaga
    17221 cgatgcattg tcgatccgtt tcttattaga tgctacctat ttaggctatt attcaactga
    17281 aaccttgact gctcttgatg agatatgtga agcaaatcag gccagctatc attttcctga
    17341 agaagatttc gttgaattga aaaaagcatc cacgcgtaat gactacttag ggatcaatca
    17401 ctaccaatgc cattttgtca aagcttacga tggagaaaat gcaatccatc ataacggtac
    17461 gggtgaaaaa gggacctctg tttataaagt gaagggaatc ggagaacgta tttataaaga
    17521 aggaattcct cgaactgatt gggactggct gatttatcca gaaggtctat atgacttgtt
    17581 gctgcgaatt aaaagcgatt acccacatta caacaaaatc tatatcactg agaacgggat
    17641 ggggtataaa gatcagtttg aagatggcat tattatggat cagccgagaa tcgactattt
    17701 gagagtctat ttggaatcct taagcaaggc gataacagcc ggggtaaatg tgaaggggta
    17761 ttttttgtgg tcgcttatgg atcttttctc atggacaaat gggtataaca aaaggtatgg
    17821 cttgttttat gttgattttg aaacccagaa gcgttaccca aaagaatcag cttactggta
    17881 caagttggtc agtgaaacca aaacgattat ttaataagtg ataatggagg aagaaaagat
    17941 gaataaagag gaattacaaa tgcttggttt tgagatcgtt gcatattcag gcgacgctcg
    18001 cagtacatta ttgaaattat tgaaagaagt aagacaagga aactttgaac atgttgattc
    18061 ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat aattcgcaaa caaaaatttt
    18121 agcggaagaa gcatctggga aagagatgga gatgggattc atttttatcc atgggcagga
    18181 tcatttaatg accactttat tgctgagaga tctgattcaa gactttattg tactgtacag
    18241 acagaatcaa ggataggaga agaacgctat ggatggaatc attaaacaaa tcgaaaaagg
    18301 gaaaccattt tttgaaaaaa tctcacgtaa tagttattta ggagccgttc gtgacggatt
    18361 tttaacagcg atgccagcta ttttattttc aagcattttc attttgattg ctgcggttcc
    18421 tgagattttt ggttaccaat ggcctgaatc tgtctccaca tggctatgga aagtctataa
    18481 ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc actgctcgct gcttggctga
    18541 ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac accacctctg tgatgctggc
    18601 ctctgtggta agtttcctgt tgttaagcgt ctctccgatt gaaggtggat tttcaacgga
    18661 atatatgggg acaaagggac tactggcttc ctttgtcgct gcatttttaa cagttaattt
    18721 atataagttt tgtgtgctga aagatattac cattaaaatg cctaaagaag ttcctggaac
    18781 gatttcgcaa accttccgag atatttttcc tttctctttt tcagtatttg cggccgtttt
    18841 aattgattta ggcattcgac aaatcttcca aatctcattt gcagaagcaa tcattacggt
    18901 gctgcagccg ctatttacag cagctgacgg gtacttagga atcgctatta tctggggagc
    18961 gatggcgctg ttttggtttg tcggtgttca tggaccgtcg atcgtggagc cggcaattgc
    19021 ggcaattatc tatgccaatg tggaaaccaa tctgcaattg ttcaattccg gtgaacaagc
    19081 ttctaaagta ctgacggtgg gtttagggaa ttttgtagga actatgggag gaactggggc
    19141 aacattggtt gttcctttta tcttcctact ctttgctaag tctaagcagt tgaaggcagt
    19201 tgggaaagct tcctttattc cagtaagttt cgctgtcaac gaaccattgc tatttgcggc
    19261 acccatgatt ttgaaccctt atttttttat tccatttttg ttaacacctg ttgtaaacgt
    19321 ttgcctgttc aagttttttg tcgatgtatt gggcatgaac agctttatgt acgttttgcc
    19381 ttgggcaact ccagcaccga tcggtttggt tctaggaacg ggcatgggta tcttagcttt
    19441 tgttctagca gcggttctaa tcgtcgttga cttcctgatc tatctaccat tttgcaaagc
    19501 atacgatgct gtcttagtag agaaagaagc acaaaaagca gaggtgatcg caaccgagga
    19561 aggtgcttct gccgatgtac gtgaggaagt acctgtggca gcgagtcaag ttatcagcga
    19621 tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc gcagggacaa gtgcgatgtt
    19681 agctaatgct ttaaaaaaag gtgcatctga atcgaaagca ccgatcagtg caatggcggg
    19741 tgcttatggt tctcattacg aaatgctgca ggattttgat atggtggtct tagcaccgca
    19801 agtcaattct tactatgatg atatcaaaga agacaccgat cgcttaggaa tcaagctggt
    19861 tgcgacaaaa ggagcagaat atatcggatt aacgagagat cctgaaaaag ctgttcagtt
    19921 tattctgaac caatttcaat aaaggaggag ccataatgaa aatgggaatt tggttgcgta
    19981 aagctgtttt atttgcagct gtgttagggg ctttgggggc tgtttcaaaa actgttgaag
    20041 catctgccag cgaatttatt cgcggagcag atatttcgat cctgtcagat atggaaaaat
    20101 ctggtgcaaa atattatgaa gacgatattt caaaagatgc cttagagatt ttaaaaaata
    20161 atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc ttataatagt aatggagaaa
    20221 gttatggagc agggacaaat gatctggaaa cgacgattga ccttgcaaaa cgagcaaaaa
    20281 atctgggact taaggtgctg ctggattttc actacagtga tttttgggtt gatcctggga
    20341 aacagaatct tcctaaagca tggcaaggtc tgacctttga agaaatgaat acggcattgt
    20401 acgactatac aaagaacgtt ctgtcggaaa tgaagcagct ggacgtttat cctgatatgg
    20461 ttcagatcgg caatgaactg aatagcggaa tgctctggcc ttatggcaag tcttggggag
    20521 aaggcggggg agaatttgat cgattggctg cttttttgaa gtctggtatc caagctgttc
    20581 gagacactca acctaaaaca actccagtaa tgctccactt agctgatggt ggcgatacag
    20641 gagcatttac ttggtggttt gatgaaatca cgagtcgagg tgtgtcattt gatttaattg
    20701 gagtgtcgta ttatccgtat tggcacggtt caatgaatga acttcaaacc aatatgaatg
    20761 cgatcagcca acggtatggt aaagaagtga tcgtagttga aacagcttat gggcatacaa
    20821 cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc cgaagcagct gcggggggat
    20881 atgaaccaac accgacagga caagcagagt atttgctgga tcttgccgat cggattcagg
    20941 cagtaccgaa taatcgcggg gcgggcttct tctattggga acctctttgg tacaacggaa
    21001 atgtgagttg ggcaacacaa gcaggtatga attatctcag tgttcaatcc actatgggaa
    21061 acgaatggga caaccaagcg atgtttgatt ttgctggaaa cgccttgcca agcttgcgtg
    21121 cgtttaaaca agcaggggcg caaataaatc tagttaaaaa tgcaagtttc gaaagcgatg
    21181 gaccaacgac cagtccttcc aattggcaaa cctggtttca acaaggaacc gctaagggta
    21241 cgatcaaaac ggaagcgggc actttttttg gggactacaa actaactttt tggcaggatc
    21301 aagcatacga ggcatcagct tatcaaaatg ttagtggcat aagcaaagga acttacacat
    21361 tgagtgccta tgtaatgtct gggggagagt ttgatactaa tcagttatat atcaaaaatt
    21421 atggtggagc ggaactaaat actgcggttg ttaaaacaag tgaatggaca aaaattacaa
    21481 tcaaagacat tccaattaca acaggtgttt gtgaaattgg ggtttatagc aaggcttcag
    21541 gaaatgcttg gacgaacgtt gattttgttt cattggtgaa acaatagact gcggatcgtt
    21601 tcgattcaag atcggaggtt cccttcagcc acatcgttag cgtagaaggc aggaatcgaa
    21661 cctgcacctc gcctttgcca aaaataacca gaaacgattt ccagtcattt ttaccaaaac
    21721 gagtaaagca ccagacttca tctacacttt gtattatgct aaagagagtt caacgatttc
    21781 gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata acataaagtt tgtttaagaa
    21841 agggtaacct tagaattccg tcgtgaatat gatttgagca cttagatgga tagaaaaaag
    21901 ttctcggaaa acagttcgtt tttcgagaac ttctttttat gataagaatg aaacaaatta
    21961 acttatatta tagtctcttt tggtagggaa ccatcttatt tttaatgaaa atcaagcatt
    22021 ttagctattg aagaatgttg atttataggg attccccctc catattatgt tggctcttta
    22081 ttcccactcc actgttgctg gtggtttaga agtgatgtca tacacgatac ggttgacgtg
    22141 ggctacttcg tttacgatac gtacagagat tttttgcaag acttcccatg ggatacgggc
    22201 aaagtcagcg gtcattccgt cgattgaagt tacagcacgg ataccgactg tgtagtcgta
    22261 agtacgtccg tcacccataa caccgacaga gcggatccct ggaagaacag tgaaatattg
    22321 ccagatatca cggtcaagtc cagcagctgc gatttcttca cgcaagatag catcagattc
    22381 gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga acacgaatac caagaccagg
    22441 accagggaat ggctgacgcc aaacgattga atcaggcatg cctaactgag tccctaattc
    22501 acggacttcg tctttgaata atgtgtttaa tggttcgatc aattcaaatt gcatatcttc
    22561 tggcagtcca cctacattat ggtgagattt gatcgtctgt gctgtttctg taccagattc
    22621 gataacgtca gtatacaacg ttccttgtgc taggaaagag acgccttctt caccagcaag
    22681 ttttgttgct tcgtcatcaa aaacatatac gaattcattc ccaatgattt tacgtttttg
    22741 ttctgggtca gatacacctt tcaacttgtc taagaagcga tctcttgcat tgactttgat
    22801 gatgttcaag ccgaattttc cgcctagact ttccattact tgttccgctt cgcctttgcg
    22861 tagcagaccg tggtcaacaa agatagatgt caattggtca ccgatcgctt tttgtaaaag
    22921 aaccccaacg acactagaat caacgccacc tgaaagacca agcaagactt ttttgtcacc
    22981 aacttgttca cggatttttt ctacttgcat atcgataaag ttatccattg tccagttacc
    23041 ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat tcgattccgt attcggaatg
    23101 acgtacttct gcatggaatt ggataccata aaaattacgt gttgtgtctt ggatagaagc
    23161 aatcggacaa tctttgcttg ttccgactgt ttcaaagcct tcaggaactt tagttaccaa
    23221 gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt tctttaaaca agacagcttg
    23281 atcgcttgtt acttctaaca aggctttccc atattcgcgg tttttagcag gctctacgga
    23341 accgccaagt ttgtacgtga tcaattgcat accatagcaa atccctaata caggaatacc
    23401 taaattgaag atctcaggat cgatcccaaa tgcattctca tcatatacac tgtttggtcc
    23461 gccagaaaga atgattccct ttggattcat cgcttttact tcttctgcag taatgcggtg
    23521 gctcaataat tcggaaaaga ctccaagatc acgaatacgt cttgtgatca attggttata
    23581 ctgactaccg tagtctaata cgataatctt ttcaacgttc gtcatatcgg caacgtttgt
    23641 caaatttatt acccctatcc ctttaaattt tatctcaaaa tagtcaaact attttaaaat
    23701 gctaatattt tcgcatgaaa atcgaatcga tgatatgatt ttcagtttta tggagaatta
    23761 tatcggctct tcctcgtgta ggcaagatat attcctgtaa atttttcaaa ttcacatttt
    23821 tccatacatc ttttgccatt ttaaaggctt cttcacgatc tccgatagca aaacgataat
    23881 aataattctc tggattttgg aaagccgtat ccagtaacgc accaaaacga tccaaatacc
    23941 atttttcgat cagcacggga tcggcatcga catagacaga aaaatcaaaa aagtcgctga
    24001 cgtagatttg ctgattcgca ggtaattgaa gcgtattgat cccctcaacg atcaagatat
    24061 caggctgctg gatcaattcg tacttgtctg gaatgatatc atacacatca tgtgagtaaa
    24121 caggtacttt tatctcttcc tgaccagatt ttacacggtt caagaaatcg atcagcatct
    24181 ccatatcata actttcagga aatcctttac ggtccatgat tccacgctct tttaatatac
    24241 gatttggata aagaaatccg tcagtcgtga tcagctgaac gtttcttcgt ttgaaggtac
    24301 gagacaaaat cgtctgcagc agtctggctg ttgtactttt tccaacggct acacttccgg
    24361 cgatcccgat aataaaaggc ggtacttcta cgtatttatg aagaaataaa cctttactca
    24421 agaacaaaga ttcaaattct ttcatataaa gataaatcag atgagcaaga ggtacataga
    24481 tatctcgaac atcctgcatg gaaatgcggt cattcaaact tttgatatta tctagttcat
    24541 cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg ccattcttct cttgccacac
    24601 ggtagtagtt cattggatca ttcatattag cctcctgcgt tctcccatca atggaactat
    24661 tttaacacaa aataaacgca aaccccacca cttaagagag attgccgatc tttttgtata
    24721 atctttataa tagaaagaaa cggagtctta ttcttgactt gcgcacggat acataaaagg
    24781 atagactgtt gtcatgaaag aaatgagaag gatggaagac atgacaaatc attactattc
    24841 tgaacgccca gatacggcgc acgattttga acaatgggct tttgagttaa aaggcagaac
    24901 ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa acagtggatt atggttcacg
    24961 tgtcctgatt gatgctttcg attgggaaga gttacctgat gaaggaaaga tcttagatgt
    25021 gggatgcggg tatggaccga ttgggttagc tttggcattt gcgacacagc ggtttgttga
    25081 aatggtcgac attaatgaac gagcggtaag tctagcgcaa ggaaacgcaa agcgtaacca
    25141 aatcgaacat gttgatatcc atcaatcgaa tatctatgaa gcagttcatg aagaaaccta
    25201 tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa aaagttgtac atgaaatttt
    25261 gacaggcgca tatcctcggt tgaagaaggg cggtacactg acaattgtga tccagaagaa
    25321 acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca tttggtaatg cagaaatcgt
    25381 cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa gaataactag ctgaaaaata
    25441 gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg gtacgtatca gttctttttt
    25501 tgttgagaag tttttaaaaa caaagaacta ttttttcttc aaaaagaaat agtaggaaca
    25561 gagtcgttgt tttttacgat aaaataaata agatacagaa cttgtataga aggctgccaa
    25621 gtcggtagat aaaggaggtt tttatcaaaa aacatacttt ccttttttct ctattctttt
    25681 cttgggggtt ttggtacact gatagggaat ttagatagaa gggagccaat aggatgaagc
    25741 tgaccatcag agatatcgca gaaatggcag gcgtatcagt aacaactgtc tcacagattt
    25801 tgaataacaa aggaagcaga tttagtgata agacaagaaa aaaagtgttg tcgatcgtga
    25861 atgaacatca ttataagccc gattatttcg cttcaaatgt gatcaatcga cattcaaaga
    25921 ccatcggaat gatcgtccct gatgtcactg atttcttctt ctccaaactg atcgaaggtg
    25981 tagagagcta tttgaatcct ttgggctatg tgatcatgtt atgcaattct cgtcatagcc
    26041 aagaaaatga gatcaagtat ttacaagagc tttcccaccg ctcagtggac ggaatcttgc
    26101 tggccacacc aaatatttta cctgagaaat atgcattaga cagcggtttt tatcaaaaaa
    26161 tgccaatcat tttaatcgat cgcggattga atcgtcggga taacggacgg cttatcgtaa
    26221 aggaatatga gggcgcctat caagctgttt cgctgtttat tgaaaatggc catacgaaga
    26281 tcggcatgct gaaggaaacc actggatact atcaattaga agaacgtttc aacggatatc
    26341 gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa atttgttgaa catggagagt
    26401 tgactgtcca aggtggatat actgcatcaa aaaaattact caaacataaa gatatcacgg
    26461 ctattttttg cgggaatgat gccatggcga tcggatgcta tcaggcgatc gatgaattgg
    26521 gcaaaaaaat cccagaagat atctcagtca taggattcga tggattaaag ctgtcagaat
    26581 acatgattcc gcaattgacg acagtgcagc agccaagttt tgatattgga ttttatgctg
    26641 cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa agttccgaac aaagtgttcg
    26701 aaacaaaatt aattattcgt gagagcgtaa aagtattgac aaagggctaa ctcggcggta
    26761 tattgcttat gtaagcattt acaaaggcta gttagtgctt tttttatttt tagtaaacca
    26821 gtttactaaa gtggtttacc tttcctaaaa ataatgtata ataccgaatg aagacaagga
    26881 ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag agggatggaa acgagctgtc
    26941 gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat ggaaagattc cagattatca
    27001 agtcagtgca ttattgatgg caatttttta tcaagacatg acaaatgaag aaatcacgaa
    27061 cttaacattg gcgattgcta attctggtga tgtcatcgat ttgagttctc ttgaaggaat
    27121 aaaggtagat aagcattcga caggtggcgt tggtgacacg accacattga ttttagcccc
    27181 cctagtagct agtgtcggag tgacagtggc taaaatgtct ggacgcggtc taggttacac
    27241 aggtggtaca ctagacaagc tagaagcaat tcccggattt cagatcgagc tttcggatga
    27301 agaatttgta cgcattgtta atgaaagtaa agtagcggta attggtcaat caggaaactt
    27361 ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc acagcgaccg ttgattctct
    27421 tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg gcaggagcag atgcaatcgt
    27481 tttggatgtg accactggag acggtgcttt catgaagaac atcgaagatg caagacgtct
    27541 ggcaaagacc atgacgagca ttgggaaact ggctaaccga gaaacagtgg cggttatctc
    27601 agatatgtca gaacctcttg gcgaagctat cggaaatagt ctagaagttg tcgaggcaat
    27661 cgaaacatta caaggaaatg gtccagaaga tctagtagaa atgtgctacg ccttaggaag
    27721 ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat gaagcaagaa cgttgcttca
    27781 agaagctctg gaatcaggta aagcgttagc aaaattcaaa gaaatgatcc aaaatcaagg
    27841 gggagaccca gcgatcgtgg aacatccaga acgaattttg actgcacgct acacaatgga
    27901 gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg gcaaatgaat taggaattgc
    27961 tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa gatattgatc acgctgttgg
    28021 attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa ggtgagtcac tattgacgat
    28081 ctatagtaac gacgaagaaa tcacttctgt cattgaatta ttatataaaa atattgaaat
    28141 tggtgaatcg gcaatgaagc caacgttgat tcatgacatc atcacagaat aaaggaaaaa
    28201 agcggacttt accgttttaa agaaaagggg aaaagaaatg gaactaaacc gaatgatcga
    28261 ccatactatt ttgaaagcag acgcatctaa agaagctgtg atgcaaatta tcgaagaagc
    28321 aaaaaaatac catttttatt ctgtctgcat caatccagca tgggttgcgc tagcgaaaga
    28381 acaattacaa ggtgagccag tagccgtatg tacagtaatc gggtttcctc taggagcaaa
    28441 cacacccgag acaaaagcat ttgaaacaac agatgccatc aataacggtg cagatgaagt
    28501 cgatatggtc atcaatatcg gtgctttgaa atcaaaggat gatcaacaag tccaaaaaga
    28561 tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt gtcaaagtta ttattgaaac
    28621 atcgttatta gatagagaag aaatcatccg agcttgcgaa atagcaaaag ctgcaggcgc
    28681 tgattttgtc aaaacatcaa ctggtttctc aacaggcgga gcaaaggtag aggatgtccg
    28741 tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa gcttccggcg gtatccataa
    28801 cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca agaatcggaa caagcgcagg
    28861 agtagcaatc gtatctggtt caactggtga aggctattaa ttttttcaaa ggagaagctc
    28921 atggcagaac tcaaacaaga atggatcaac acagctattg aagcgttaga taaagcctat
    28981 gttccttatt cccattttcc ggtaggcgct tgtctcgtaa cggaatcagg caagatttat
    29041 caaggcatca acattgagaa tgcatcattt ggattaacga attgtgccga gcgcacagct
    29101 tttttcaaag cagtatctga aggagaaaaa acatttacgc atctagtcgt agcggggcac
    29161 acccccgatc ctatctctcc ttgtggtgca tgtcgacaag taatggcaga attctgttcc
    29221 cctgatatgc cggttacgct agtaggagac aatggtgtga cgaaggcaac gaccgttcgt
    29281 gcactgctgc cttatgcatt tactgaaaaa gatctataac tcatgttcat tcagtcagct
    29341 gactgttgaa aaataaaaca attattttag gaggctttac agaaatgaaa aaagcaaaat
    29401 tatttggttt aggtgctgtc gcactagcag cagggttatt tttaggtgca tgcggcaaca
    29461 acggctctac tgattcatcc ggtggcaaaa gctcatcaga cacaacaact gcagcattga
    29521 tcacagacac aggtggtgta gacgaccgtt cattcaacca gtcagcttgg gaaggactag
    29581 aaaaatgggg gaaagatcaa ggactttcac gaggaaatga tggcttccaa tatttccaat
    29641 cttcaaatga atcagattac atcccaaata ttgaccaagc attgaatgct ggattcaaaa
    29701 cgatttttgg tattggttat aaactaaaac cagcgatcca agaacaagca acaaacaata
    29761 caggtacgaa ctttgttatt atcgatgatg tcatcgatgg attagataac gttgtatctg
    29821 caactttcaa agacaacgaa gcttcttatc ttgcaggtgt tgcagcagct tatacgactg
    29881 aaacaaacgt agtcggcttt atcggcggtg taaaaggtga agtaatcgat cgttttgatg
    29941 ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt aggaaaagaa atcaaagtat
    30001 tgaatcaata tgctggtgac ttctctgctc cagataaagg acgttcaatt gctcaaggta
    30061 tgtatgcaca aaacgcagat atcatcttcc atgcttcagg cggtacaggt aacggtgtat
    30121 tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa agtttgggtt atcggtgttg
    30181 accgcgacca atcagacgaa ggcgaataca cattaaacgg cgaaaagaaa aacttcacat
    30241 tgacatctac actgaaagca gttggaacag tagtagaaga tttggcacaa aaatcagcgg
    30301 acggtaaatt ccctggcggc gaacacactg tttatggatt gaaagaagac ggtgttggtc
    30361 taacagaagg acaactttct gacgaagcga aaaaagcagt tgatgaagca aaagaaaaaa
    30421 tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga aaactaaaac catttctata
    30481 gccttgttag acacatgttt gacaaggcta tggtttgatt agaacaagaa ttgttcattt
    30541 atccaagctg ccttgtgaca gtttggataa gggaacaact ccctgaagta atgtttgttt
    30601 caaaagaaga acgctcacta agcgtgaatc ttagtcaatc gttgccctag atagaaatcg
    30661 ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca tagaaatgca gaatattacc
    30721 aaagaatttg gaacattcaa ggcaaatgac aacatcaatt tacaagtaaa ggcaggagaa
    30781 attcatgcgt tgcttggaga aaacggtgct ggcaaatcta cattgatgaa cgtgctttcc
    30841 ggattattag agccgacatc agggaaaatt ttgatgcgtg ggaaagaagt aaagatcaca
    30901 agtccgacca aagccaacca attagggatt gggatggtcc atcagcactt tatgcttgtt
    30961 gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg agcctagtcg cgcagggatg
    31021 cttgaccata aaaaagcacg aaaagagatc caaaaagttt ctgaacagta tggattgtca
    31081 gtcaacccag atgcttacgt tcgtgatatt tcagttggaa tggaacaacg ggtagaaatt
    31141 ttaaaaacac tttaccgagg agcagatgta ctgatttttg atgagccgac agctgtattg
    31201 acccctcaag aaattgatga attaatcgtg atcatgaagg aattagtcaa agaaggcaag
    31261 tcgatcattt tgattacgca taagttagat gaaatcaaag cagtagctga ccgctgtaca
    31321 gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta aagacgtaac ctcacaacaa
    31381 ttagccgata tgatggttgg aagaacggtt tcattcaaaa cgatgaaaaa agaagcgaag
    31441 cctcaagaag tcgttttgtc tattgaaaat ctagtggtga aagaaaatcg tggattagaa
    31501 gccgtgaaaa acttgaactt agaggttcgt gctggcgaag tacttggtat cgctggaatc
    31561 gatggaaacg ggcagtcgga gttgatccaa gctttgactg gtttgcgaaa ggcagaaagc
    31621 ggacatatca agctaaaagg ggaagacatc actaataaaa aaccccgaaa aatcactgaa
    31681 catggtgtag gacacgtgcc agaagaccgt cataaatacg ggttagtcct agatatgaca
    31741 ttatctgaaa atatcgcact acaaacctat catcaaaaac cttacagtaa aaacggcatg
    31801 ctgaattatt cagtaatgaa tgaacatgcc agagaattga tcgaagaata tgatgttcga
    31861 acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg gaaatcagca aaaagcaatt
    31921 atcgctcgtg aagtcgaccg agatcctgat ctgttgattg ttgcaaatcc aactcgtgga
    31981 ctggatgtag gtgcgatcga atttattcat aaacgtctga tcgaacaaag ggacaaatac
    32041 aaagcagtgt tactgatcag tttcgaatta gaagaaattt taaatgtttc ggatcgtatt
    32101 gctgttatcc atgaaggaga aattgtcggt atcgttgatc cgaaagaaac atctgaaaat
    32161 gaattaggtc tattgatggc gggctatacc ttagaagaag cacgaaaaga gttagaaaag
    32221 ggggctggcg cacatgaatg atcgcagcga aaaattccgt aatttattag tgcctgtact
    32281 ttcagttgtt ttaggattga tcttaggcgc gatattgatg gctgcttttg gttttcagcc
    32341 catccaaggt tattcttcta tgctagatgc agcccttggt tcgcaaagag ggataggtga
    32401 aacgttaagg caagcaacgc cgttgatttt tacagcatta ggtttttctg tagctaactc
    32461 agctgggttt ttcaatattg ggctttctgg acaagcactt tgcgggtgga tcgtcagtgt
    32521 ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt ttgcttccgt tatgcgtgat
    32581 cttaggtgcc ttagctggtg cgatggcagc ggctgttcca ggtttacttc gagcattttt
    32641 tggaacaagt gaagtgatcg taacaatcat gatgaactat atcttattat acgtaagcac
    32701 atttgcttta catgaagtga tgcctgaaag ctatcgctca agtttggact cttccaatat
    32761 gatcagtcaa aatgcctcac tgcggttacc atggttaaca caagcttttg gcggctctcg
    32821 cgtaaactca ggattatttt tagcaatcat cgcgcttatt ttcgtttggc tgctgatgaa
    32881 gaaaacgact ttaggatttg aaatccgttc tgttggattg aatccttttg cttctgagta
    32941 tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg gtcatttctg gcgctttggc
    33001 agggcttggc ggtgtggttg aaggattagg aacgtatcaa aacttctttg ttcaaacgac
    33061 ttcgctatct attggatttg acggaatggc tgtttccttg cttggttctg gatcagcaat
    33121 cggtattctt ttatcagcga tcttgttcag tattttgaag atcggtggac ttggcatgca
    33181 gacaggagca ggtgttccgt ttgagatcgt caatgtatcg attgctttga ttatcttctt
    33241 tgtcgggatc aacttcctga ttcgtttcgt catggctaaa gtcttccaag ggaaaaaaca
    33301 agaagagatc gttgcgacaa tagaatcgaa accaacgaat caaaaccatg aagggggcga
    33361 actataatgt cgactatcga attaattgcc ttgatcctta cttctacact ggtttattca
    33421 acaccgctaa ttctaacgtc actaggcgga actttttctg aacgaagcgg gatcgtaaac
    33481 gtagggctag agggaatcat ggtcatgggt gcttttagtt ccatcgtttt caacttgacg
    33541 atgagtccat cacttggttc tatgacacca tggatcgcta ttttagtggg tggcgtcgta
    33601 ggtatcctat tttctctgat tcacgcagta gcaacagtca gtttgcgtgc tgaccatatt
    33661 atcagcggga cagtaattaa tctgatggca cctgctttag gtgttttctt gatcaaagca
    33721 tggtatggta aaggtcaaac tgataacatc acgcagaatc tggggtattt ttctttccca
    33781 ggattagcag atattccggt cattggacca attttcttta aaaatacatt cttacctgct
    33841 tattgtgcta ttttgattgc tgtcctagct tgggtgatca tcttcaagac gaaattcggc
    33901 ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg acacattagg tatcaatgta
    33961 tatgctatgc gttattcagg cgtactgatt tctggcttgt taggcggtat gggcggtgct
    34021 gtttttgctc agtcgatttc cggtaacttt tcagctggta cgatcgttgg acaagggttc
    34081 atctccatgg ctgctatgat ctttggtaag tggaatcctt taggggcaat gggtgcctca
    34141 ttgttctttg gttttgctca aagcttgagt atcattggcg cacaattacc agttatttct
    34201 tcgattccgc cagtattgct gcaaattgct ccatatttgc tgacaatcat tgtgctggtt
    34261 gttttcttag ggaaagcttc tggtccaaaa gcaaacggga agaactatat caaatcaaaa
    34321 taatctttta gcgaataaaa agggtgggtt acgggaagtg tttttcgtct cgcccttttt
    34381 gttttaaagg caataaaaat aaaaagaaag aaggaataat catgtttaaa cgcgtacatc
    34441 tgatcgtcat ggattcagta ggaattggag aagcaccaga tgccgataag ttcggtgatg
    34501 ttggttctga tacattagga cacattgcga aagaagcagg attgaacgtt ccacatttag
    34561 agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt ggaatcagtg aaagatcatc
    34621 aaggctatgc gacgaaatta gaagaagttt ctgtagggaa agatacgatg acaggccact
    34681 gggaaatcat gggattgaat atcaaaactc catttcgtgt gtttcctaat ggattccctg
    34741 atgatctgat caaacaaatc gaagaatttt ctggccgtaa agtcgtatgt aacaaacctt
    34801 atagcggaac agctgttatt gacgattacg gtgaacacca aatgaaaaca ggcgatttaa
    34861 ttgtatatac ttctgccgat cctgtccttc agatcgcggc acatgaagaa atcattcctt
    34921 tagaagaatt atatcggatt tgccaattcg ttcgtgatat aacaaaagat gatccgtata
    34981 tgattggccg aatcattgca cgtccgtacg tgggtgaacc aggagacttc acacgaacaa
    35041 gcaatcgcca tgattatgcg ttgaatccat tcggacacac agtccttgat tctttgaaag
    35101 aagcaggaaa ggacgtgatt gctgttggaa agatcaacga tattttcaac ggacaaggaa
    35161 tcactgaatc tgtccgcacg aaaagcaata tggatggcgt tgaccagctg ctgaaagtta
    35221 tgaaaaacga tttttcagga atcagcttta ccaatttagt agattttgat gcattatacg
    35281 gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga agaatttgac ttacgaattc
    35341 cagaattgct tgaagcgatg gaagaagacg acttgctaat gattacagcc gatcacggaa
    35401 acgatccgac gtttactggt accgatcata cgcgagaata tgtaccgtta ttggtttaca
    35461 gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata ttattcagat atttcagcaa
    35521 cgattgctga gaactttagt gtttcttcga ctgaaaatgg cgaaagcttc ttgaaattat
    35581 taaaataatc tttttaaata ggagaaagca aatgaccaag ttaagcgaga tgttacaaga
    35641 aacgacccag tttatccttg ataaaggagt aaaagaaatt gattttggtt tgattctagg
    35701 ttcaggatta ggtgaattag cagatgaaat cgaagatgct gtaatgattt cttatgatga
    35761 gatcccgttc tttcctgttt cgacagtagt tgggcatgca ggaaagctag tttatgggtc
    35821 tctggcaggc aagaaagtgt tagccatgca agggagattc cactactatg aaggtcattc
    35881 catgcaaaca gtgacctatc cagtacgtgt gatggccgga ctaggggccc attcagtcat
    35941 tgtgactaat gcatgtggtg gtgtcaacga atcatttgta ccaggagatt tgatgctgat
    36001 taccgatcat atcaatttta ctggtgaaaa tcctttgatc ggtccgaatg aagatgcaat
    36061 gggccctaga tttccagata tgagtcaagc ttatacgcct gactatcaag caacagcaaa
    36121 agcagcagca gaaaaactag gtttggatct taaagaaggc gtatatatgg gctattctgg
    36181 accaacttat gaaacgcctg cggagatccg aatgtctcgg acaataggag ccgatgcagt
    36241 agggatgtcg actgttccag aagtcatcgt agcagctcac agcggattaa aagtgttagg
    36301 aatctcttgt attaccaact tagcagcagg tatgcaagcg aatctgagcc atgaagaagt
    36361 tgtagaaaca actcagagag tcaaacaatc ttttaaagca ttggttaaag aaacattgac
    36421 attattgtaa taggaggaac aataaaatga gtgtgcatat tgaagcgaaa gaaggcgaga
    36481 tcgccgataa gattttactt ccgggagatc ctttgcgagc taaatatatt gcggagactt
    36541 ttttggaaga tccagtttgt tacaatcagg tacgcggtat gttaggcttt accggcaaat
    36601 ataaaggaga acgtatttct gttcaaggaa caggaatggg aatgccatca gccaccatct
    36661 atgcccatga attgatccag tcgtatggtg taaagaaatt gattcgagta ggtacatgcg
    36721 gtgcattgtc aaaagacgtc catgttcgtg atttagtact agcacaaggt gcagcgacca
    36781 gttcttcgat gatcgaaaaa aatttccaag cctttcattt tcctccaatc agtgatttca
    36841 atctattact gaaagcatat gagatagcta aagaaaaggg ctatacggtt catgtaggaa
    36901 atgttctttc ggaagattct ttctacaaag atgatttgac agagacgttc caattagctg
    36961 aacttggcgt tttaggagtg gaaatggaag cagcggctct ttattactta ggcgcgaaat
    37021 accatgtgca gacattaagt ttgatgaccg ttagcgacca tttgatcacc ggtgaagaaa
    37081 caacagctgc agaacgtcaa tctacgttca atgaaatgat cgaagtagga ttggaaacag
    37141 cgatagcaga ataagaagga aatgaaaaag ctgccctgca ttaagtaata agaacatcca
    37201 agcaaaaata gctcctcatg tttttgactt ggctggactt attattgcaa atgtaagctt
    37261 ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta actctgagtc acaaggaaca
    37321 atttcaaaaa acagcttttc atgtttgatg aatattgtga cttgtgaccg agaagttggc
    37381 aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa tcgtgtcaca gtcccttttt
    37441 tatagtgttt tttataggta gtatttttta gcaactgtta agtcatcatt taattcataa
    37501 acaagtggtt gacctgttgg aatttcaaga tccatgatgt cttcgtcaga gataccttcg
    37561 atatgtttag ctagggcgcg taatgagtta ccatgtgcag ctactaaaac agttttgttg
    37621 tctagtaatg ctggagcaat ttcatcttgc cagaatggca aagcgcgttc taatgtcact
    37681 ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca ttgcgtaacg acggtcattt
    37741 gctgcagaac cttcgtcagt ttcttccatt aatggaggaa gagtatcgta agaacgacgc
    37801 cagatgtgca cttgttcgtc gccgtatttt tcagctgttt cttttttgtt caaaccttgt
    37861 aatttaccat agtgacgttc gtttaagcgc catgatttga tttgtggtac ccaaagttga
    37921 tctgaatatt ctaagatcaa gttacatgtt ttgattgcac gagttaaaac agaagtgtaa
    37981 gcaacatcaa attcgattcc agcttctttg attttgcgtc cgccttcttt tgcttcttcg
    38041 attccttctg gtgctagatt tacatcagcc caaccagtaa attggttcaa tgcattccat
    38101 tcactaagac cgtgacgaga aaaaactaat tttggcatgt ttagctctcc ttttaagata
    38161 ggtttatatt tctgaaattt tcagttctgt tttattgtac aattttttgg aagagatttc
    38221 catcgaaaaa ttagataaga ttctatgaga aaacaagtag agaatataaa aaaacgaaca
    38281 gtgcccacgc aactgttcgt ttttaggtat tagatgcata attgctcgat ttctttttca
    38341 ggtaaattga tatatttata acatgttcca actgaaacac cgcattttga agaaataaat
    38401 tggatcgttt cttttttttc ataatagaga cgtcggattt ttttgatcgt ttttgcatcg
    38461 atttttggtc ttccgccgat ttttcctttt ttacgagctt catctaatcc aactaatgta
    38521 cgttctttga tcaatgcgca ctccatgttt gctaggtttt ccattaattg gaaatagatt
    38581 tttcccattt cgcgcgtatc gattccttca tcaagactaa tcaagtgcag cccgcgatct
    38641 ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt tgcctaatcg atgaagttgg
    38701 caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca ctgactccaa atgaacagca
    38761 gtagaatcat tttgttccac ttcatatgtc tcatggaaaa tttcttgaca accaaagtca
    38821 gataattgat caacctgagt tgttaaatca acgtcattta tggttgtgcg tgcataacca
    38881 ataattttca tggtgattcc tttctagcag tgattttcta actggatata acagtaaaaa
    38941 tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa ttttccgctg tcttttttta
    39001 ttggatgatc aagcagtttt tctttattta cgacggattg cgtcaagaat ctcaacgcct
    39061 ttttctgagc cgacaactac tttagaaacc atgtttagga aaagcccatg ttctactacc
    39121 ccaacaagtt catctaaata ggtagctaag ctttctggct gttcgatgac ttctagatgc
    39181 agatcaatga tgtaatgacc accatctgtg gttaagactt ctccgttttc gtctgtacgc
    39241 aagacgggtt ggaatctttt ttcttcaaaa atatgaagta gctgttggga gccataaggg
    39301 atcacttcaa ctgggagtgg gaacttccca agtttatcga ctaatttaga agaatcaacg
    39361 atccaaatcg tttcttttga gtacgtagcg actattttct cgaaaagcaa agcagcgccg
    39421 ccgcctttga tcccttgaaa atcagcactg atttcatcag caccgtctat tgtcaaatcg
    39481 actacgggga cttcatcaat actctttaac ggtattccta atttttccgc ttgttctttt
    39541 gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt cttcacgcat acggcgacca
    39601 atctcttcta ccatataata ggcggttgaa ccggtcccga gacctacgat catcccgtcc
    39661 tttacgaatt tcgcggcttc aatgccagct aattgtttta aattcatctt tgcgtccacc
    39721 tttttttagt ttgagcatcg tgctttcctc actattttag cgtgatttac ggtaaaaaga
    39781 taccattctt ttttattcca ataaagcttt ttcaaaaaaa attgcatctc ttgttgacat
    39841 gttttttcat tcgtgatatt ctaacaaagg tgctttatct acaggtttct gtgaagaaac
    39901 gtgctgactg tttatcaaag catatttgat aaggatgcag acattgcatt tattttttat
    39961 cacaaaaaaa gaaccacctg gatgtgtgga actagacgca aatcgtggga aggaggaaac
    40021 aaggaatgcc tacaattaac caattagtac gtaaacctcg taaatcaaag gtggaaaaat
    40081 ctaattcacc tgctttgaac aaaggatata acagctttaa gaaaactcaa actaacgtaa
    40141 actcacctca aaaacgtggg gtagcaactc gtgtgggtac aatgacacct aaaaaaccga
    40201 actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa cttaattgaa gttactgctt
    40261 atatcccagg gattggtcat aacttacaag aacacagtgt tgtattatta cgcggtggtc
    40321 gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg cggtgcttta gatactgctg
    40381 gtgttaacga ccgtaaacaa agccgttcta aatacggaac taaaaaacct aaagcttaat
    40441 tttaattatt aaacaaatga aacttgcttc tactatatag aagtaattac tatgaacaat
    40501 atttcggaag gaggagttac ggatgccacg taaaggtcct gttgcaaaac gtgatgtttt
    40561 accagatcct atttataact caaaattagt aactcgcttg atcaaccgtg taatggttga
    40621 cggaaaacgc gggattgcag ctaacattat ctataatgcc tttgacttga tcaaagaatc
    40681 tacaggtaac gatccattag aagtgtttga acaagcaatg aaaaacgttc aacctgttct
    40741 tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa gtaccagttg aagttcgccc
    40801 tgaacgccgc gttactctag gtcttcgttg ggtagtaaac tacgctcgct tgcgcggtga
    40861 acacacaatg gaagaacgct tagcaaaaga aatcatggat gctgcaaaca acacaggtgc
    40921 ttctgttaaa aaacgtgaag acactcataa aatggctgat gccaaccgtg cgtttgctca
    40981 ctatcgctgg taagattctc tctgtttggt cggcttttat aagtcgacct cagatagtgt
    41041 ccttattttt agcaactaga tagtaaagag aggagaaaca aggagaatga ccagagaatt
    41101 ttctttacaa aacactcgta atatcggtat catggcccac atcgatgctg gtaaaacgac
    41161 tgctactgaa cgtatcttgt actatactgg taaaatccat aaaattggtg aaactcatga
    41221 aggagcttca caaatggact ggatggaaca agaacaagaa cgtggtatta cgatcacttc
    41281 tgctgctact acagcacaat ggaagggtca ccgaatcaac atcatcgaca caccaggaca
    41341 cgtagacttc acagttgaag ttgaacgttc attgcgtgta cttgatggtg ctgtaactgt
    41401 tcttgatgca caatcaggtg ttgaacctca aactgaaaca gtttggcgtc aagcaacaac
    41461 ttatggtgta cctcgtatcg tatttgcaaa caaaatggac aagatcggtg ctgacttctt
    41521 atattcagta tcaactttac atgaccgttt gcaagcaaac gctcacccaa tccaattacc
    41581 aattggtgcg gaagacgact tcacaggaat tatcgacctt gtaacaatga aggctgaaat
    41641 gtatacaaac gatcttggaa cagagatcga agaaacagaa attcctgaag aataccgcga
    41701 attagctgaa gaatggcgcg aaaaattggt tgaagctgta gctgaaactg atgaagaact
    41761 tactttgaaa tacttagaag gtgaagaaat cactgaagct gagttaaaag aaggtatccg
    41821 ccgcgcaaca gttaacgtag aattctaccc agtactatgt ggttcagcat ttaagaacaa
    41881 aggggttcaa ttactattgg acgctgttct tgattacttg ccatcaccgt tagatatccc
    41941 agctatcaaa gggattgacc ctaaaactga tgaagaagta gaacgtcctg cagacgacag
    42001 cgctcctttc tcagctttag catttaaagt tatgactgac ccattcgtag gtcgtttaac
    42061 tttcttccgt gtgtactctg gtgttttaca atcaggttca tacgtacaaa acgcaacaaa
    42121 aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat gccaactctc gttcagaaat
    42181 ctctgaagtt tacgctggag atatcgctgc tgctgttggt ttgaaagaca caactactgg
    42241 ggacacacta tgtgatgaaa agagtctagt tattcttgaa tccatggaat tcccagaacc
    42301 agttatccaa gtcgctattg aacctaaatc aaaagctgac caagataaaa tgggtgtggc
    42361 tttacaaaaa ctatctgaag aagatcctac tttccgtgct gaaacaaacg tggaaacagg
    42421 cgaaacaatc atcgctggta tgggtgaact tcacttagat atcatcgttg accgtatgcg
    42481 tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa gtatcttacc gtgaaacttt
    42541 ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag tctggtggta aaggtcaata
    42601 cggtcacgta tggattgaat ttacaccaaa tgaagaaggt gctggtttcg aatttgaaaa
    42661 tgcgatcgtc ggtggggttg ttcctcgtga atacattcca gctgttgaaa ctggtttgaa
    42721 agatgctatg gaaaatggtg tcttagctgg ctatccatta gtagatatca aagctaaact
    42781 ttacgatggt tcataccatg atgtcgattc aaatgaaact gccttccgtg ttgctgcttc
    42841 tatggcatta cgtgcagcag ctaagaaagc taatccagta atccttgaac caatcatggc
    42901 tgtagaagtt gttatccctg aagattattt aggtgatgtt atgggtcacg taactgctcg
    42961 tcgtggacgt gttgaaggta tggaagctcg cgctggcggc caacaagttg ttcgtgcgat
    43021 ggttccactt gctgaaatgt ttggttatgc tacaactctt cgttctgcta ctcaaggtcg
    43081 tggtacattt acaatgacat ttgaccacta cgaagatgta ccaaaatcag tacaagaaga
    43141 aatcattaag aaaaacggcg gaaaagctga ataatttctt gaaaccggat agtcctgcaa
    43201 agagattatc caaagagact atatttttaa tatagtttcg tgtaaaataa ttatcgatga
    43261 tatgggcatg tggtgtacct tgtgtacatc atatacctat cagacaaata aaaaatatat
    43321 tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa tttgaccgtt ctaaaccaca
    43381 cgttaacatt ggtactatcg gacacgttga ccatggtaaa actacattaa cagctgcaat
    43441 cacaactgta ctatctaaga aaaacggcgg ccaagctatg gcttacgatc aaatcgatgg
    43501 tgctccagaa gaacgcgaac gcggaatcac aatctcaaca gctcacgttg agtatgaaac
    43561 agatacacgc cactacgctc acgttgactg cccaggacac gcggattacg ttaaaaacat
    43621 gatcactggt gctgctcaaa tggacggagc tatcttggta gtttctgctg ctgacggccc
    43681 aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa gttggtgttc cttacatcgt
    43741 tgtattcttg aacaaagtag acatggttga tgacgaagaa ttactagaat tagttgaaat
    43801 ggaagttcgt gacctattaa cagaatacga attccctggt gacgatgttc ctgtagttgc
    43861 tggatcagct ttgaaagctc tagaaggcga cgcttcatac gaagaaaaaa ttcttgaatt
    43921 aatggctgca gttgacgaat acatcccaac tccagaacgt gacaacgaca aaccattcat
    43981 gatgccagtt gaagacgtgt tctcaattac tggacgtggt actgttgcta caggtcgtgt
    44041 tgaacgtgga caagttcgcg ttggtgacga agttgaagtt gttggtattg ctgaagaaac
    44101 ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa ttgttagact acgctgaagc
    44161 tggagacaac attggtgctt tactacgtgg tgttgcacgt gaagacatcc aacgtggaca
    44221 agttttagct aaaccaggta caatcacacc tcatacaaaa ttctctgcag aagtatacgt
    44281 gttgacaaaa gaagaaggtg gacgtcatac tccattcttc actaactacc gtccacaatt
    44341 ctacttccgt acaactgacg taacaggtgt tgttgaatta ccagaaggaa ctgaaatggt
    44401 tatgcctggc gacaacgtaa caatggaagt tgaattaatc cacccaatcg ctatcgaaaa
    44461 cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt ggtgccggtg tcgttacaga
    44521 aatcaaagct taattcactt aagttttaaa gtaaagcaac atttattcgg acgtaatcgc
    44581 tcggaacgaa ggtcttagga tctttgttcc gagctttttt atttattgca ggatcaggaa
    44641 aaaagacagg agtattataa atagaagaaa cacgaaataa aagagtcagt attttctaaa
    44701 tgaaacttta tgaaaacaaa atgtttttta caagaaaaag ccttgctttg tgagtttata
    44761 tatattataa tgacaaaggt gcgtttactt tagtgaattg cacagacgta atcagaatga
    44821 tttcgtcggc taagaaacga gaggttgcga cacgcccgga cgctttgcca cgaacgagcg
    44881 tgacggaaat tttcgtggag ctatgtctac ttttcaaaat aggcgaagga gggaacaaga
    44941 tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga acaccgtatt ttagatcaat
    45001 cagcggataa aatcgtggaa actgcaaaaa gaactggagc tagcgtgtct ggtccaattc
    45061 cattaccaac tgaacgcagt ctttacacaa tcatccgtgc gactcataaa tacaaagatt
    45121 cacgcgaaca attcgaaatg cgtacacaca aacgtcttat cgacattgtg aacccaacac
    45181 caaaaactgt tgatgctttg atgaagctag acttaccatc tggtgtaaac atcgaaatca
    45241 aattataaaa ctaaaacaaa aataatggag gtgtactcat gaccaaagga atcttaggga
    45301 aaaaagtggg aatgacacaa atcttcactg aatctggtga attaattcca gtaactgttg
    45361 tagaagctac tccaaacgta gtactacaag tgaaaacaat ggaaacggat ggctacgaag
    45421 ctattcaagt tggttaccaa gatatgcgtg aagttttatc aaacaaacct gcgaaaggtc
    45481 atgttgcaaa agcaaacacg gctcctaagc gcttcattcg tgaattcaaa aatgttgagc
    45541 taggagaata tgaagtagga aaagaaatta cagtagatgt tttccaagca ggagacatta
    45601 ttgatgtaac aggtactacg aaaggtaaag gattccaagg ggttatcaaa cgccacggac
    45661 aaagccgcgg accaatggct cacggttctc gttaccatcg tcgtcctggg tcaatgggtc
    45721 cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc tggccgtatg ggtggcaacc
    45781 gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc agaaagaaat gttatcttga
    45841 tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac tatcaaatca gctgtgaaag
    45901 ctaaataatt gtaggaagaa aggaggaact aaggaatgcc gaatgtagca ttattcaaac
    45961 aagatggaag ccaaaacggt gaaatcacac ttaacgaaga aatcttcgga attgaaccta
    46021 atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc gtcattaaga caaggaacac
    46081 acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg taaaccatgg cgtcaaaaag
    46141 gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca atggcgtgga ggtggcgtag
    46201 tctttggacc aacaccacgt tcttacagct acaaacttcc taaaaaagtt cgtcgtttag
    46261 caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa cttggtagca atcgaaggct
    46321 tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt tcttgctaac ttatctatcg
    46381 actctaaagt attggttgtt ctagaaaaag gtaacgactt tgctgcttta tcagcacgta
    46441 acttaccaaa cgtttctgta gtaacttctg ataatgtgag tgtgctagac gttgtatcaa
    46501 atacaaaagt gttagcaaca caaactgctc ttactcaaat tgaggaggtg cttgcataat
    46561 gaacttacta gacgtaatca aacgcccagt gatcactgaa aaatcaatgc ttgccatgga
    46621 tgacaagaaa tacacttttg aagtggacac tcgcgcaaac aaaactttag taaaacaagc
    46681 ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac atcgtgaacg tacgtgcgaa
    46741 attcaaacgt atgggcaaat atgcaggata tacaaaaaaa cgtcgcaaag cgatcgttac
    46801 attgactgaa gattcaaaag aaatccaatt attcgaagct gctgaataag cactaataga
    46861 taactcatta aattaggagg gaaaaacgtg gcgattaaaa agtacaaacc tacctcaaat
    46921 ggtcgtcgta acatgacagg ttctgatttt gctgaaatca caacatcaac acctgaaaaa
    46981 tcattgttac aaccattgaa aaaccatgct ggacgtaaca acaacggccg catcactgta
    47041 cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga tcgacttcaa acgtaacaaa
    47101 gataacgttg ttgcaactgt tcaaacgatc gaatatgatc caaaccgttc agctaacatc
    47161 gcgttagtac actatgaaga tggagtgaaa gcttacatct tagcacctaa aggactagaa
    47221 gtgggtatga aacttgtttc aggtccagaa gcagatatca aagtcggaaa tgctcttcca
    47281 ttagaaaaca ttccagttgg tactgttatc cacaacattg aaatgaaacc tggtaaaggt
    47341 ggacaattga tccgttctgc tggtacaagt gctcaagtac ttggtaaaga aggcaaatac
    47401 gtattgatcc gcttgaactc tggtgaagtt cgtatgatct tagctgcatg ccgtgctaca
    47461 atcggttctg taggtaacga acaacacgaa ttaatcaaca tcggtaaagc tggacgctct
    47521 cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa tgaaccctaa tgatcaccca
    47581 cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag caccagtttc tccttggggt
    47641 caaccagctc ttggttacaa aactcgtaac aaaaaagcta aatcagacaa acttattgtt
    47701 cgtcgtcgca aaaataaata attactttga ccatgtgtcg cacattttga gaggaggttc
    47761 accatgggtc gtagtttaaa gaaaggacct tttgtcgatg agcatttaat gaaaaaagtt
    47821 gaagctcaag caggggttga aaagaaaaaa gttatcaaaa cttggtcacg ccgttcaaca
    47881 gttttcccaa gttttgttgg atataccatc gcagtttatg atggacgtaa acatgtacca
    47941 gtttacatcc aagaagacat ggtaggacac aaattaggtg aatttgcacc tacaagaact
    48001 tatcgtggac atgctgctga cgataagaaa acgaaacgct aatttgaggg gaggataaat
    48061 ccaaatggca gaacaaatca catcagctaa agcaactgca aaaacagttc gcacttcacc
    48121 tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa agtgtcgcag atgcaatttc
    48181 aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt gaaaaagtat tgatgtcagc
    48241 agttgcgaat gcagaaaata actttgactt agatgttgaa aacttggtag taagcgaagc
    48301 ttttgttaac gaaggaccta caatgaaacg tttccgtcct cgtgcaaaag gatcagcttc
    48361 tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta tcagaaaaat aaggagggat
    48421 aatcagtggg tcaaaaagta catccaattg gaatgcgtgt aggcatcatc cgcgactggg
    48481 atgctaaatg gtatgctgaa aaagagtatg ctgagttctt acacgaagat ttaagaatcc
    48541 gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc aacagttgaa atcgaacgcg
    48601 caacaggtcg cgtaaacatt tcaattcaca cagctaaacc aggtatggtt attggtaaag
    48661 gcggttctga agtcgaaagc ctaagaaaag aattaaacaa attaactggt aaaagaatcc
    48721 atatcaatat cgtggaaatc aaaaaaccag atctagatgc aaaattagta ggtgaaggaa
    48781 tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc tcaaaaacaa gccatccaac
    48841 gctcaatgcg tgctggcgct caagggatca aaactcaagt atctggtcgt ctaaacggag
    48901 cagatatcgc tcgttcagaa ggatactcag aaggaactgt tcctcttcat actttacgtg
    48961 cggacattga ttacgcatgg gaagaagcag atacaacata cggaaaacta ggagttaaag
    49021 tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa cactgagaaa ggagggaaat
    49081 aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa ttccgcggaa aaatgcgcgg
    49141 ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac ggtttgcaag ctgttgattc
    49201 acattggatc acaaaccgcc aaatcgaagc tgctcgtatc gcaatgactc gttacatgaa
    49261 acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa tcttatactg ccaaagcaat
    49321 tggggtacgt atgggttctg gtaaaggggc acctgaagga tgggttgcac cagtaaaacg
    49381 tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa gtagctcgtg aagcgttacg
    49441 tctagcttct cacaaattac caatgaaaac taagatcgta aaacgtgagg aaatgggtgg
    49501 tgaatcgaat gaaggttaaa gaaatcagag aattaaccac tgccgaaatg cttgatcaag
    49561 aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca attagcaaca ggtcaattag
    49621 aaaacactgc acgtattaaa gaagtacgta aatcgattgc acgcatcaaa actgtgttgc
    49681 gtgaacaagc taagtaatta tggaaggagg ccattaagcg tatgactgaa ggaagaaatc
    49741 aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat ggataaaaca attaccgttg
    49801 ctgtcgaaac aaagaaaaac caccctatct atggcaaacg catgaactat tctaagaaat
    49861 acaaagtgca tgatgaaaac aacacagcaa aagttggcga catcgtgaga attatggaaa
    49921 ctcgtccatt atcagctaca aaacgtttcc gtttgttgga agtagtcgaa gaagcagtta
    49981 ttatctaata acacgagatt ttcctatata gattgaatgc aaaatctgaa aggaggatac
    50041 acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga taactcaggc gcacgtgaaa
    50101 ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac tgctaacatc ggtgatgtga
    50161 tcgttgctac ggttaaacaa gcaacgccag gtggggttgt caaaaaaggt gacgtcgtta
    50221 aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac agacggttca tatattaaat
    50281 ttgatgaaaa tgctgcagtg attattcgtg atgataaaag ccctcgtgga acacgtatct
    50341 ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat gaagatcgtt tcactagcac
    50401 cagaagtttt ataatcttga gacacttatc aaaggaggtg cgaaacagtt atgtttgtta
    50461 aaaaaggcga taaagttaaa gttatcactg gaaaagacaa aaacaaagaa ggcgttgtac
    50521 tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg tgtaaatgtc gttaaaaaac
    50581 accaaaaacc ttctcaagct gctcctcaag gtggaattgt tgagatggaa gcgccaattc
    50641 atgtttctaa cgtgatggtg gttgactcta ctggtgtagc tggccgagtt ggctacaaag
    50701 aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg tgaagtttta gataaataaa
    50761 agtttaagga aggagggtct tactgaatga accgcctaaa agaaaaatat cttaaagaag
    50821 taactccatc attgatggaa aaatttaact atagctctgt tatgcaaaca cctaaagttg
    50881 aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc aaacgctaaa aacttagata
    50941 aagcagttga agaattaact ttgatcactg gtcaaaaacc aatgattaca aaagctaaaa
    51001 aatcaatcgc tggattccgt ttacgtgaag gaatgccaat tggtgcaaaa gttacattgc
    51061 gcggagaaag aatgtacgaa ttcttagaca aattggtttc tgtttcacta ccacgtgtac
    51121 gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg tggaaactat actttaggta
    51181 ttaaagaaca attgatcttc ccagaagtag attatgattt agtagataaa gtacgtggta
    51241 tggacatcgt tattgtaaca acagcaaact ctgatgaaga atctcgtgag ttgttgacac
    51301 aattaggcat gccattccaa aaataattaa aggaggcgaa ctacgtggct aaaaaatcaa
    51361 tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca agcttatact cgttgcgaac
    51421 gttgcggacg tccacattca gtttatcgta agttccatct ttgccgtatt tgcttccgcg
    51481 aacttgccta taaaggtcaa attcccggcg tgaagaaagc tagctggtaa aaagtaaatt
    51541 cgcataagaa ggaggtaaaa gatcaatggt catgacagat ccaattgcag attttctaac
    51601 tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta gaagtacctg catcaaaaat
    51661 taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc gttcgtgatg ttgaatacat
    51721 cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa tttggtaaaa acggcgaacg
    51781 tgttatcaca aacttaaaac gtatctctaa accaggtttg cgtgcttatg tcaaagctga
    51841 cgaagtacca aaagtattga acggtttagg tatcgcaatc atttcgactt ctgaaggtgt
    51901 tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc gaagttatcg cttacgtatg
    51961 gtaatcaagt agaatctaca aggaggtgtc tttaagtgag ccgtatcgga aataaagtcg
    52021 ttgttatccc tgaaggagta acagttactc aagacggaaa caacgttaca gttaaaggac
    52081 caaaaggtga attgactcgt actttttcag cagatatcaa aatgaatatc gaaggaaacg
    52141 aagtaacttt cactcgtcca aacgacagta aagaaatgaa aacaattcat ggaacaactc
    52201 gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg tttccaaaaa gcgttagaac
    52261 taatcggggt tgggtaccgt gcacaattac aaggatcaaa acttgtattg aacgttggtt
    52321 actcacatcc agtagaaatc acaccaccag ctggagtaac tgttgaagta ccagctaaca
    52381 cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg cgaattagct gcaaacattc
    52441 gtggaactcg tcctccagaa ccttataaag gtaaaggtat tcgttatgtt ggcgaatatg
    52501 tacgccgtaa agaaggtaaa actggtaaat aatcgtttag aaaaattgca tagaagccag
    52561 cagcaggaaa aaggcatttg gctgaagttt accttcaaaa aaatacattt ttacttgtgc
    52621 cgcagcttct atttttcgaa acgtatttac tgcttgaaat agtagtacaa taaaaataaa
    52681 gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa cacgtcaaaa gagacatcgt
    52741 cgtgtacgta acaatatctc tggtactgct gagcgcccac gcttgaacgt ttttcgttct
    52801 aacaaaaaca tctacgctca aattattgat gacgtagcgg gtgtaacgct agcaagtgcc
    52861 tctaccttgg ataaagaaat ttcaggtgga acaaaaacag aagcagcaca agctgtcggt
    52921 aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag tagtagtctt tgaccgtggt
    52981 ggataccttt accatggccg tgtgcaagct ttagctgaag ctgctcgcga aaatggacta
    53041 gaattttaga agaaggagga ataccattca tggtttatat cgatccaaaa catttggaat
    53101 tagaagaccg cgttgttgca attaaccgtg taacaaaagt tgttaaaggt ggacgtcgtc
    53161 tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg acacgtagga tttggtacag
    53221 gtaaagctca agaagttcct gaagcaatcc gtaaagcaat tgaagatgcg aagaaaaact
    53281 tagttgaagt acctatggtt ggttcaacaa tcccacacga agtaatcggt gcttttagtg
    53341 gtggtagaat cctaatgaaa cctgctgtag aaggttctgg ggttgctgct ggtggaccag
    53401 ttcgtgccgt attagaatta gctggggtag cagatatcac ttctaaatct ttaggctcaa
    53461 atacaccaat caacgttgtt cgcgcaacag ttgaaggttt gaaacaattg aaacgtgcag
    53521 aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt aatcggataa ggaggacaac
    53581 aataatggct gaattaaaag ttactttaaa acgcagtatt atcggacgtc ctcaaaacca
    53641 acgcgataca gttaaagcgt taggtcttac aaagattaac agttcagtgg ttaagccttc
    53701 taatgaagca attaaaggca tgatcaatac tgtttctcac ctagtggacg ttgaagaaat
    53761 ttaatttaga aaaatcataa ctagaacatt aaggaggtgc caaacctatg aaacttcatg
    53821 aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg tgttggtcgt ggtacttcat
    53881 ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca aaaagctcgt tcaggcggcg
    53941 gtgtgcgttt aggatttgaa gggggacaaa caccattgtt ccgtcgttta ccaaaacgag
    54001 gattcacaaa cgtgaaccgt aaagactatg cagtcattaa tcttgatgta ttgaaccgct
    54061 ttgaagacgg agctgaagta actcctgttg ctttagttga agctggaatc gtgaaaaacg
    54121 aaaaagctgg aatcaaagta ttagctaatg gggaactaaa caagaaatta actgtgaaag
    54181 cagcaaaatt ctctaaagca gctcaagaag caattgaagc ggctggtgga tcaatcgagg
    54241 tgatctaatg tttagactat taaaagatgc ttttaaagta aaagacatta gatcgaaaat
    54301 cctatttact gtatttgtgt tgtttgtatt tcgcctaggt gcacatatta ctgtaccagg
    54361 cgtaaatgct gcttcattgc aaaacctttc ttctttgcca tttttcaaca tgttgaactt
    54421 ggtaagtggt agtgcgatgc aaaacttttc cattttctca atgggggttt caccatacat
    54481 tactgcttct atcgtcattc agcttcttca aatggacatc gtgcctcgat ttgttgaatg
    54541 gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa gcgactcgat atctgacatt
    54601 agtattggca tttatccaat ctgtcggtat cactgctgga ttcaatcaat acgctcaatt
    54661 aggtttcgtg aataatccta acgtagcaac ttacgtaacg atcggtttga ttctaacagc
    54721 cggtacgatg tttgttactt ggctaggaga acagatcaca gaaaaaggta tcggaaatgg
    54781 cgtatcaatg atcatttttg caggtatcat ttctagattg cctgaaagta tcagagaaat
    54841 ttatgaagat tactttataa atattgatcc ttcagacata tggaaatctg ctatttttgt
    54901 ggccatttta ctagtagcgg tcttgttgat cgtgacattc gtaacatttt tccaacaagc
    54961 tgaacgcaag atcccgatcc aatatacgaa acgcgtagct ggcgcgccta caagcagcta
    55021 tctgccgttg aaagtaaatg cagctggagt tattccagtt atctttgcta gttcgtttat
    55081 tgctacgcca aatgctgttt tacaagcatt gagcggtaga ttcggttctg aaaactggta
    55141 caaagtgatg atggagatct ttaactataa tacagcacct ggtgctacga tttatacgat
    55201 tctgatcgtt gccttcactt tcttctacgc ctttgttcaa gtaaaccctg agaaattagc
    55261 ggaaaacttg caaaagcaag gaagttatat accaagcgta cgccctggta aggggactga
    55321 agagtatgtc tcaagattac tgatgcgttt aagtacagtt ggtgcagtct tccttggttt
    55381 agtggcattg cttccaatca ttgctcaaat ggtttgggat cttccacaat caatcggatt
    55441 aggcggtaca agcttactga tcgttatcgg tgtagcttta gaaactgcga aacagttaga
    55501 aggcttaatg ctgaaacgta aatatgttgg attcattgag taagaaagcg tgttgaggtt
    55561 tcccctcaac acacgttctc acacatttat taggagggaa aacaatgaac ctcattttaa
    55621 tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa aatcattgat gcttatggta
    55681 ttccgcacat ctcaacagga gatatgttcc gcgcagcgat gcaaaacgaa acagctcttg
    55741 gcctggaagc aaagtcttat atggataaag gtgcattagt tcctgatgaa gtaacaaatg
    55801 gaatcgtgaa agagcgacta gctgaaccag atacagagaa aggcttctta ttagatggct
    55861 ttccacgtac gctagatcaa gcaaaagctc tggacgcaat gctaaaagat ttgaataaaa
    55921 aaattgatgc tgtcatcgat atccatgttg gtgaagaaat cttggtcgaa cgtctagccg
    55981 gccgatttat ctgcagcaat tgtggagcaa cttaccataa aattttcaac cctacaaaag
    56041 ttgaagacac atgtgatcgt tgcggtgggc atgaattcta tcaaagagaa gatgataaac
    56101 ctgagacggt taaaaatcgt ctggctatca acatcaaaaa tagtgaacca atcttggctt
    56161 attataaaga acaaggtttg ctaaacacta ttgatggtgc tcgtgaaatc gatgctgtat
    56221 ttgcagatgt acaaaaaatc attgaaaaat agcacgattg cccgtagccg acttgcatta
    56281 tgcagttact cttgtcaagt tcaataaatt atgatagaat atgtcagtcc gacttctaga
    56341 gaatcctcta gatgatccat tttgagaatt ttgaggtggg aactgcagtt tccgccattt
    56401 tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt gcgtggcaaa agaagatatg
    56461 attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg caatgtttaa agttgaacta
    56521 gaaaacggac accaagttct tgctactgtt tcaggtaaaa ttcgtatgca ttacatccgt
    56581 atcttacctg gtgacaaagt aacggttgaa ttgtctccat acgatcttaa ccgtggccgt
    56641 attacttatc gctttaaata attgtactcc gtaaaactac aggaggtatt atcatgaaag
    56701 taagaccatc agtaaaacca atgtgcgaac attgtaaagt aattcgtcgt aaaggacgcg
    56761 ttatggtgat ttgcccagca aatccaaaac ataaacaacg tcaaggataa ttggaggtgc
    56821 tataaatatg gctcgtattg caggagtaga tattcctcgt gataaacgtg tagtagtttc
    56881 acttacttat atctatggta ttggtaacac tactgctaaa aagatcttag ctgatgctgg
    56941 tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa caaacagatg ctatccgtgc
    57001 agaagtagat aaattaaaag ttgaagggga tcttcgtcgt gaagtgaact tgaacatcaa
    57061 acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat cgccgtggat tgcctgttcg
    57121 tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc ccagctcgcg ctatcgctgg
    57181 caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc atggcagcaa aaaaagtgaa
    57241 tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt gcacatatcc attctacatt
    57301 caataacact atcatcatga tcactgatac tcacggaaat gcattagcgt ggtcatcagc
    57361 tggttcatta ggtttcaaag gaagcaaaaa atcaactcct tttgccgctc aaatggcagc
    57421 agaaactgct acaaaagcag caatggaaca cggattaaag actgttgaag taacagttaa
    57481 aggacctggt tctggacgtg aagcagcaat tcgttcatta caagctacag gtttagaagt
    57541 gactgcaatt cgtgacgtga ctccagttcc tcataatggt gcccgccctc caaaacgccg
    57601 tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt aacgtcattg aacaagacac
    57661 ttttcgtttt gaaaggggta aagataagaa tgattgagtt cgaaaaacca agaatcgcaa
    57721 aaattgatga agaaaaagat tatggcaagt tcatcgttga acctcttgaa agagggtatg
    57781 ggactacttt agggaattcc ctacgtcgta ttttattatc ttctttgcca ggtgctgcca
    57841 tcactaatat tcaaatcgat ggtgtactgc atgaattctc taccatcaaa ggtgttagag
    57901 aagacgtcac tcaaatcatc ttgaacatta aaggcttagc gctgaaaatg tatggccaag
    57961 aagaaaaaac ccttgaaatc gatattaccg gacctgctac agtaactgct ggcgatatta
    58021 tcgttgatag tgatgtagaa attcttaaca aagatatgta catctgtagt gtctctgaag
    58081 gagctacgtt ccatgctcgc ttaacagtga aacctggacg tggttatgtt caagcagatg
    58141 aaaataaaaa agaagatatg ccaattggcg ttcttccagt cgattcaatc tacacacctg
    58201 ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg acaccgtgaa gattttgata
    58261 aattgacgat ggagatttgg acagatggtt caattgaacc gttggaagca atgagtttgt
    58321 ctgcgaaaat catgactgaa catttggata tttttgtgaa cttaactgat gaagcaaaaa
    58381 atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga aaaaatgttg gaaatgacga
    58441 tcgaagagtt agacttgtct gttcgctctt acaattgttt gaaacgtgca ggaatcaata
    58501 ctgtacaaga acttacaaat aaatctgagc ctgaaatgat caaagtccgt aacttaggac
    58561 gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt aggtttaggt ttacgtaaag
    58621 aagattaaaa ccttttacga aggagggaaa ccaacgtgag ttatcgtaaa ctaggacgca
    58681 catctagcca acgtaaagcg atgttgcgtg atttaacaac tgatttatta atcaacgaac
    58741 gtattgtgac tactgaagct cgtgcgaaag aagttcgctc aactgcagaa aaaatgatca
    58801 ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc tgcggctttc gtacgtaatg
    58861 aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat tgaatcagct ttacaaaaac
    58921 tgttcaacga tattgcacct cgttacgcag aacgtcaagg cggatacaca cgcattttga
    58981 agacagaacc aagacgcggt gatggtgcac caatggttgt cttagaactt gtctaaaatc
    59041 acactaataa catcacttta tagatgattc ttttagagtg ttatgatgtt ggaagatatt
    59101 tttccgagtc tagctcagcg ctgctcctca agcgaatatc gcttggggag taagcactca
    59161 tcataaagtg tttttttata ccttcaatta cctgtcatga cagatatgtt tgaaggcata
    59221 aaaaaacatt ttaagcgaga aataattgaa aattttgtct ttttttgata gtgttagtag
    59281 gaactttagg atgaagaagg agtaatcatg gagccaatta ttgaattaga aaagataaat
    59341 tataaatacc agccagatga tcttcgcccc gcattgaaag atgtctcctt tacaattgat
    59401 aaaggtgagt ggatcgctat tattggacac aatggttcag gaaaatcgac acttgccaaa
    59461 acgatcaatg gattgcttct gccagaatca gggatcgtga aagtgggaaa tcaaatattg
    59521 gatgaagaaa atatttggac gatccgacag atggttggaa tggtttttca aaatccagac
    59581 aatcagtttg ttggttcgac agtagaagat gacgttgctt ttggtcttga aaatcaaggg
    59641 attcccagag aagaaatgct agtgcgtgtg aaagatgcac ttgagaaagt tagaatggct
    59701 gagtttgctt cacgcgagcc tgctcgttta tcaggagggc aaaaacaacg tgttgccatt
    59761 gccggcgtgg ttgccttacg acctgatatc attattttag atgaagcaac cagtatgcta
    59821 gatccagaag gtcgtgaaga agtgatctct acgatcaaga agatcaaaga agaaagtcaa
    59881 ttgaccgtta tatctatcac tcatgatatt gatgaagcag ctaatgccaa tcggatacta
    59941 gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa aagaaatttt ttctgctggt
    60001 cctgaactga tcgacttagg tctagatcta ccatttcctg aaaaactgaa gagcgcactg
    60061 aaagaacgtg gggttgatgt gcccagtgaa tatatgacag aagaaaggat ggtggattgg
    60121 ttatggacat ccgttttgaa caagtagact tcacttatca gccgaataca ccatttgaac
    60181 aaagagcctt atttgacatc aatatgacga tcaaagaaaa cagttatact gcattagtag
    60241 ggcataccgg aagcgggaaa tcaaccttac ttcagcattt gaatgcgctt gttaagccaa
    60301 caagcggtac agtccatatt ggagaacgag atattcagcc ggatacggat aataagaatt
    60361 taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt tccagaagca cagctattcg
    60421 aagaaacggt agcaaaagac attgctttcg gtcctaaaaa ctttggtgtc agcgaagaag
    60481 aagcactagt cctagcaaaa gaaacattag aacaagttgg gctggatgaa agctatttgg
    60541 aacgttcgcc atttgaactt tcaggagggc aaatgcgtag agtagcaatc gctggtgtgc
    60601 ttgccatgag gccggaagta cttgtattgg atgaaccaac ggcaggactt gatccccagg
    60661 gcagaaaaga aatgatggag atgttttggc gtcttcataa ggaacagcag atcactattg
    60721 tattagttac gcatttaatg gatgatgtag ccaattttgc agattatgtc tatgtgttgg
    60781 aaaagggacg aatcgttaat agcggggagc cgcaagaggt ctttcaaaac attgaatggc
    60841 taaaagaaaa acaactaggc gtacctactg ccaccgagtt tgcagaagaa ttaatggcta
    60901 aagggatgaa ctttgctacc ttgcctttga cagctgaaga attagcagac gctatcgtcc
    60961 attatgctgg aggaaatgcc catgatgaat aaattgatat ttggtcgtta tatgcctgga
    61021 gattccttga tccatcgatt ggatccccga gctaaattat tagccagttt ttattttatc
    61081 ggaatcattt ttttagcaaa taattgggaa acgtaccttt tgttggcatt tttcacatta
    61141 ctttctgtct tcttgtcaaa agtagatttg aaatttttta tccgaggcat tcgcccattg
    61201 atctggctaa tcctcttcac tgtagctttg caggtcttgt ttacaagtgg cggagaaact
    61261 tattggagtt ggggtgtttt ccatatcact gaatttggtg tgatgaacgg cctctttatt
    61321 ttctgtcgat tcgtgttgat catttttatg tcgactctac tcacgcttac tacaccgcct
    61381 ttggaattat cggatgcgat tgagtacttg cttcgtccat tgaaagccgt acggttccca
    61441 gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt ttgtgcctac attgatggac
    61501 gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg ttgattttgg tgaaggaaac
    61561 ctagttcaga aaatgaaagc agtcattcct ttgctgattc ctttatttgt cagcagcttc
    61621 aaccgtgcgg aagatcttgc gactgctatg gaagcaagag gctacaaagg tggggaagga
    61681 agaacgaaat atcgtgtatt gcattggcat aatagagaca cgatggttat cattgctttt
    61741 gtattattaa ctgtgctact gatcttttta agaggataaa cgttcagtgg gccgctatct
    61801 attcttttct tgctgatctg tttgcaagaa aggatgcaag cagtgtatga caagaaatat
    61861 tagggtctgt ggcagactaa ggtcacaggc ctctttcttt tatctgaaaa gaaagaacga
    61921 aaaaatttta tagaaaaatc attattccag ataacctttt aggaacaaag gagagaaaaa
    61981 catggtacgt tacaaagcaa tcattgcgta cgacggaaca aattttaatg gattccaaaa
    62041 acagccaaat gggcgtactg ttcaagaaga agtagaaaaa acattacaaa aaatggcaaa
    62101 tggaaaagaa atcacggtct ttggttcggg aaggacagat gccggagtac atgcgatcgg
    62161 gcaagtaatc cattttgatt atccagagga gcgtccgtta gaacgaatgc gtttcgcgct
    62221 agatacccag tcaccagagg atattgctgt aagacaagta gaaattgttt cagaagactt
    62281 ccacgcaaga tatttggtca aagaaaagac gtatcaattt cgagtggata tagggaaacc
    62341 acgcagtcct tttcgacgcc attatgcaag ttattttcct tacccacttg atttggaaaa
    62401 aattcagcgg gcgcttcctg atttattagg gactcacgat ttcacctctt tttgtgcatc
    62461 aggaagctcg atagaggata aaatacgtac gatctacgag gctaagatgg aggtaaatga
    62521 aacaaaagac gaattgttgt ttacatttag gggaaatggc ttcttgtata agatgatacg
    62581 gatcttagta ggaacgcttt tgaaaattgg caatggccga ttgcctgaag atagtatccc
    62641 agatattatt gcgaaaaaag atcgtaatgc agcaggacct acagcacacc ctgaaggact
    62701 ttatttgtat gaagtgaaat atgaataaga ggttatgata gaagtggtca gcttcaagaa
    62761 ataagaaggt atttacgaaa attacttctc aaaattttgc aaaatttcgg cttattttcg
    62821 aagaagctac ttctggaaca ccgtttaagg aagaggtcgt gaaatcagcg ttttgacctg
    62881 agtattagag aaacaaacgg gaaaatagct cctcatattt tgccgtttgt tgagctaata
    62941 ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc gtgagcctgt catttaactc
    63001 tgagtcacaa agagcaattt caaaaaacag cttctcatct ttgatgaata tcgtgacttg
    63061 tggacgaggc gttgataagt gaatcatctt tttgttacct attttttctg taaccaaaaa
    63121 acgatggaac gttgttttga ttgcccttgg tgcggacagt ctgaacaggt tccatcgttt
    63181 ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt gttcttctat tgctggatca
    63241 atcgtgccat aaaaggggcg attgcggtca aggtaccaga cataaagaat aaacaatgca
    63301 atacatagga caaaaaggat tgcacctatc gtaaatcctt caggcaagta actgaaagtg
    63361 acagtatgtt tacctgctgg aacttttatc atcaagaatg cgtctttgaa attgctgacc
    63421 ttgactggtt tcccatcaat tttagctttc catcctttgt cataaggaat agttgtcacc
    63481 aacatggaat cttcagcggt atttacagtc ccagaagctt ttctgccagt ggcttccatt
    63541 tcgacacctt tttctttgat ctgattcatt gcggcttgat aggctacaac atctagacca
    63601 acgactttag gctccatgaa acttatttct ttcgtcccat aaaaacttgc agtaaatgtc
    63661 actgttgtct cttgaggata atagccaaga tcatagtatt gaccagaaat gttgatttgc
    63721 gtttttcgcg atgtaccatt gacagtgatc gtcgcactag aactttctaa ttgcgcaaaa
    63781 ttggttggga acaaacttaa gtaagcttgt gtatttgcag gcacatggac ttcccaagtg
    63841 agctcttttg gctggttatc tgctgtttct gagtaagtga cgccagtcgt tgtctttgtg
    63901 atcgtcgtat tcaactgatt cttcaaagta ggtgtataga atgtaaaata ctgttcattt
    63961 agaccagaca atgtattgat caagtttgtc tgactggtca aattatctgt cactggctgc
    64021 tcaacatcat taacggacaa cggtgcagta aatgctagtg gcaatgcatt gacattctga
    64081 tacagtgtat agtcgccgct ttgaccagct tggcggaagc catatttact gaacgtgctt
    64141 tcgtttttag aaatgttata tttgattcct gtaaacccat ccatcagcaa agtattattg
    64201 ttataacgga tattcaaatt tgtccctctt gaacggaaac ctaatttatc caggtaagag
    64261 gaagaattac gatttcttat agaagaaaac aaactgatac cactgtaacc atagttgatc
    64321 gaatcgtttg cagatactgg atccagattt tccaagcggt aaaacgagtc ggaatctttt
    64381 tttgtttcat ttacaagagc tttcaagtca ggataaggat cagtatataa actgcgggaa
    64441 gcataattcc aatcatcaag aatgccatgg atcatactgt tcgtattgac cagtgcttca
    64501 gcagacatga tcaataataa caatatactc agatgattga atgaaagttt tttatgctga
    64561 taaaatccca cagcaaaagc ataaatccct aagaaaacca ctgtcaatac aaaggaagtc
    64621 atcgtcacat aggtgtagct tccttcaggt ttgatgcccc atgccaccgc aaagagagca
    64681 gctacgacca aaatgattcc taacaacagc ccacgatcgt cttgttctat cttttcccat
    64741 ccttttcctg caagcaggag cactaagaaa gagaacagat aggcataacg gaataaaaac
    64801 atattcggtg catgcatacc atgccagaac aaattcaatg gaacaagata aaaacttgcg
    64861 ataagtatgg cgaaaagact gccgtacaaa aatttatttt tcaacggtac tttccgactg
    64921 gcaaaataaa acagacagag gactaatggt agcagacctg cgtaaacgaa cggaatcgat
    64981 ccgtattttg tcgtgtcata aacaccaatc atatttttca tgattagatc cagataagaa
    65041 gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct cgccatttga ccgaagatcc
    65101 agcactgctg gcaatacaat gatcattgaa gcgccgcctg ccagtaaaga agtgatacca
    65161 taaggaacaa tcgttttttt atattctgac cagtttgtca atagacgggc gataaaatat
    65221 aagaaagaaa atacgccaat cataaaaccc atataaaaac tggataaaaa caagagtaaa
    65281 taactgataa ataaaagttt cggccgttta agatccataa cacgatgaat ccccaaaatc
    65341 actaatggaa gataaacaaa tgcatccagc cacatgatga tctccgaatg tgcagtgata
    65401 aatgagatca atgcgtaact gacgctaagt gcaacatgcc cccagcgagg aatcttgaac
    65461 gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga ccttaagcaa agtcagaaca
    65521 tacagtgcat ctggcatcat ctggtttgga aaaaagaaca ccagtggcgt gaagatcccg
    65581 cctagatagt aagaaattaa agataaataa ttcaatccta gagaagcatt ccatgtataa
    65641 aaaatacttt gctttccaag aagaacattt cggaagctgg catgaaaatt agaaaactgt
    65701 gaaaaggcat cacttgccaa aatacttctg ctgcttccag gatagattcc gatacttaga
    65761 taaacaagtg ctaaaatcaa aaacggaatc aggaaactag ctgctgcgta gcgtccgttt
    65821 tctctaaaga atgactttaa attttttttc atatttattt tccaccaaat ttctatgaag
    65881 ttgtattcag tttatcatat ccttgttttt ctctgcttaa aaagagtcta gttttcacaa
    65941 aaaaataaaa tttagaataa ataacttcat aatttgttcg tataacaaaa ataaacgcaa
    66001 aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt tattaaataa aaaaccgttc
    66061 actatctgaa cggtccaagt atcattcaat taaacgcgtt caacttttcc tgatttcaaa
    66121 gcacgagttg acacccaaac ttttttaggt tttccgtcga ccataacgcg aactttttgt
    66181 aagttaggtt taacagtacg ttttgttgag ttcatagcgt gtgaacggtt gtttccactt
    66241 tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg taatttcctc ctttgccttg
    66301 atttggagca atagaataat tcagctcata ccagactaac atatcatata gaatgggaat
    66361 ttgcaagtac attttcatag atacaattga caattgagaa gaataattgt aaattaaaca
    66421 aggttatacc tgaaattttg caaggttttt gagtactttg ggtaactgcc ttttatttca
    66481 agttgcgcta tgataaaata tgatagaaga aaaatgggag ttttttaccc gttaaggagg
    66541 ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc attgaaatta ccaatgatgt
    66601 aattgcaaca gttgttggtg gcgccgcgac agatgtgttc ggtgttgtag gaatggccag
    66661 caaaaatcaa attaaagata atattactga gattttgcgt aaagaaaatt actcaagagg
    66721 agtagttgtc cgccaagaag ataatggtat tgctgtagat gtttatacga ttatcagcta
    66781 tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa aaagtgaaat acaatctaga
    66841 ggcattatta ggcgtaactg ccaattcagt taatgtcttt gtacaaggtg ttcgtgtact
    66901 gccagactag gcaggagact ggctggtaac tcagcagtcg atctgaagga ggattatcta
    66961 ggtgagtgta acagaaataa gtgcaagcca gttccaggaa atggtccagg caggtgcgaa
    67021 tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat gtattccctg tgccagatgg
    67081 cgatacggga acaaatatga atctatctat gactagtgga gctaaggcag tagtagattc
    67141 aacctcagaa aaagtaggag aattagcagc aatgctttca aaaggattgc tgatgggtgc
    67201 gcgcggaaat tccggcgtta ttttgtctca attgtttcgt ggattttcta agcaaattcc
    67261 agatgttgtc tcattaaatg cttctgatct tgctgcagcc ttcactcatg gagttgaaac
    67321 tgcgtataaa gcagtaatga aaccagtaga aggaacgatt ttgacagtag ctagagaagc
    67381 agcgaaagct ggagaaaaga aagcaaaaag tactgatgat gtcgttgaag taatgacagc
    67441 tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca gacttgcttc cagtcctaaa
    67501 agaagtcggt gtcgtagaca gtggagggca aggactgctg tttgtttatg agggcttttt
    67561 aagtgcattg aatggagaat tccaagcgga tgaaacatat gaaccttctc cagcagaaat
    67621 ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa ggtcaaatgg cgacagaaga
    67681 tatccatttt ggttactgta cagaaatcat ggtaaaaatc ggagaaggac ctacagtcga
    67741 tagtacattc gattacgaag aattccgtaa ctatttagat ggtataggag attctttact
    67801 tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat acagaaaacc caggagaagt
    67861 cttgaattat ggacaaaaat tcggttcatt agtcaaaatc aaagtcgaca acatgcgctt
    67921 gcagcatgag acgattttgg aacacgatga agaagtgaac gagtttgcga aaaaagaaat
    67981 accacgtatc ccgtatggta tcgtagcgat cgctgctggt aaaggcgtcc aagagctgtt
    68041 tgaaagttta ggcgctaatt atgttatcag tggtggacaa acaatgaatc caagtacgga
    68101 agacattgtt aaagcgattc aagaagtaaa cgcagataaa gtgattgtct tgccaaacaa
    68161 taagaacatc ttcatggcag ctgatcaagc agcagaagta gcagatatcc cagtagcagt
    68221 tgttccttca agaacgattt cccaaggatt gacagctatg ctttcattca atgatcaagc
    68281 ttctttagaa gaaaacaaag aaacgatgac agaaatgttg tctagcgttg tgagcggtca
    68341 agtcactcac gcgatcagag atacctcaat tgacggtgta gagatcaaag aaggagactt
    68401 tttgggcatg atcgatggaa aaatcctgat ctctaaccca gatatcacag caacagcgtt
    68461 aagtacacta gaacaaatga tcaatgagga cacagagatc gtaacgatct tggcaggtga
    68521 tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa ctaacagaaa aacatcctga
    68581 tttggaaatc gagatccacc aaggagatca gcctgtctat ccttatctat tttctgctga
    68641 ataatttctg tgtcagaata tctttctaac acagtattca ttcataaaag gccttcggtt
    68701 agtgatcagg tatgatcgct gaccaagtcc tttttttgtt aaaggaggga ggaaaaattt
    68761 atgcgttctt tagatgatcc aatcactatg ctggcaggag tcggagaaaa aagagcagct
    68821 agtcttgcca gcttgggcat ccaaacgatt gaagacttac tgacttatta tccttttcgc
    68881 tacgaagata ttcaggaaag aaatctaaac gagatccagg atcaagaaaa ggttactttg
    68941 aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg gttataaaaa aagccgattg
    69001 caatttcgta tgatgcaaga acatgatgtg ttcaacgttt ctttttttaa tcaaccttat
    69061 ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat acggtaaatg ggatgcaaag
    69121 cgtaaagcct tgaacgggat gaagatttta ggttctcaaa caatggatga cttttcgccg
    69181 atatatcacg tcaacaaatc aattcgtcaa acgacattag ttgatctaat caaaaaaggg
    69241 tttcaagaat acggcacatt gattgaagaa aatctgccaa acaaccttgt ggagaaatat
    69301 cgactgcttg accgagcttc tgctgtaaga agtatgcatt ttccaaaaga ccacgaagaa
    69361 aaccatcaag ccaaacgacg tgtcgttttt gaagagttct ttttatttca aatgcgtctt
    69421 caaggattga aaaaagcaga aaaagcagaa acgaatggtt tggagatcct ttatgatgtc
    69481 caaaaattga aacaatttac tcaaaagcta ccttttgaac tgacaaatgc acaaaaacgt
    69541 gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc atatgcagcg acttttgcag
    69601 ggagatgtag gtagcggaaa aacagtggtt gccgcgattg cgttatacgc taccgttaca
    69661 gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct tggcacaaca acatatggaa
    69721 agcttgcaac agctgtttga tcccaatgaa gtaaccatcg cattgattac ggggtcaacg
    69781 aaagcaaaag aacgacgtga gctccttgaa aaactagagc aaggggaaat taacgtcgtg
    69841 atcggcacac atgcattgat ccaagatgga gtcgaatttc agaatttagg tctagttatt
    69901 acggatgagc agcaccgttt tggcgtgaac cagcggaaag tacttcgtga aaaaggctgg
    69961 cgaccagatg tcttatttat gacagcgact ccgattccta gaacattagc tattacagca
    70021 tatggtgaga tggatgtatc tatcattgat gaacttccag ctggacgtat cccgatcgaa
    70081 acacgctggg taagaacacc tcaattggac agtgtactgg attggacgaa aaaagaactg
    70141 gcaagaggac atcaaatgta tgtcatctgt ccgctgattg aagaatcaga agcattagat
    70201 gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac tatttgcacc aaaatatgaa
    70261 gttggcttgt tacatggtaa aatgaagaat caggaaaaag aagtaatcat ggaagccttc
    70321 aaagacaacc agatgcagat attagtttcg actactgtaa ttgaagtagg ggtaaacgtg
    70381 ccgaacgcga ccgtcatgct gatcatggat gcggatcgat ttggattggc acagctgcac
    70441 caacttcgtg gacgtgttgg acgcggaagt gatgcttcct actgtatctt agttgctaat
    70501 cctaaaaatg aactaggtgt ggaacggatg aaaatcatga cagagaccac caatggtttt
    70561 gtactaagcg aaaaagatct ggaattacgt ggtcctggtg aagtatttgg cttccgtcaa
    70621 tctggtctgc ctcaatttgc gattgctgac ttggtgacgg atggaaatgt tttggaggta
    70681 gccagagaag aggctgcagc cctttggcaa ataaaggatt ggcagatgct tcctgagtat
    70741 cagcctttag cgcaaagcct ccaaatagaa aatcaggata atcgttattt cgattagcag
    70801 actgtgctat actttatact gatgacggaa aaaggagtgg aaacaatgaa aattgccgta
    70861 gatgcaatgg gcggagatca cgcacctcaa gcaattgtag aaggcgtggc tttagcgcag
    70921 caagattttc cagaagtaga attcttactt tacggaaaag aagcagaaat caagaaatac
    70981 ttaacaaatg aaaaaaacat cacgattatc catacagacg aaaaaatcaa tagtgatgat
    71041 gagccagtaa aagcaattcg acgaaaaaag actgcatcaa tggtccttgc tgcacaagca
    71101 gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga atacaggcgc gctactagca
    71161 gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac gccctggctt gatgtctacc
    71221 ttgccagtag tagggaaaga aggtgccggt ttcgatatgc tggatcttgg cgctaacgca
    71281 gaaaacaaac cagaacattt gttgcaatac ggtattttag gttcttttta tgcacgtaaa
    71341 gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca acggaacaga agcaacaaaa
    71401 ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga atgaaacaag cttgaatttt
    71461 attggaaacg tagaagctcg tgagctactc aatggtgtgg ctgatgtagt ggtcacagat
    71521 ggatttacag gcaacgctgt tttgaaatct attgaaggaa cagcaatgaa tatgatgaat
    71581 ctattaaaat ctgctattct aaatgaaggg atcaaaggaa aaatgggcgc tatgctttta
    71641 aaagacggct tacgttcttt gaaagcagaa atggattatt ccaaacatgg cggtgccgtt
    71701 ttgtttggct tgaaagcacc agtcattaaa actcatggag caacaggccc cgatgctgtt
    71761 cgctatacga tccgccaaat ccacacaatg cttgagacag atgtagttgg acaattagtc
    71821 gaacaatttg aaaaaagcga agaatagtat ttggatatct gaagcgatcc gttccattga
    71881 aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag ccatggtgta ggtaattgac
    71941 aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa gaagtattta acaaagtagc
    72001 gaaaattatt tcaaatcatt ttgagataga taccgataaa gtgacggatg aattgaacat
    72061 caaagatgat ttaaaagctg attcaattag tattatggaa ttcgttttag agcttgaaga
    72121 tgaattcggt acggaaattt cagatgaaga cgctgaacaa attgaaacag tcggtggcgc
    72181 agtagattat atcagcagcc atcttaaata atttcaaata aaagcaaaga aggataaaaa
    72241 gctgcatgca gctttttatc cttctttttt taatcttttt gacacgtaaa agtcattttt
    72301 ctgataattc tggcgataaa cagaaattat gttgcaaagt aaagcggttt tctatataat
    72361 tattaataat tcattacaca aagataagaa taacctttgt tataaaacga tttattctgt
    72421 gtaatgtcct tttttattaa gaaaaacttc catttaggaa gcagagaggg gtattcgatt
    72481 gtccgataac caattattag aagttcagaa cctacataca ggattccgac tcaaagatga
    72541 ctattacgat gcagtagatg acgtttcatt tactttagac aaaaacgaga ttttagcaat
    72601 cgttggggaa tctgggtgcg ggaaaagtac cttggctact acgattatgg gattacttga
    72661 tcctaataac acaaaaatta caggtgagat tttatataac gatctgaatt taatcgacct
    72721 gaacgaaacg ctctataata aaatccgcgg aaatgatatc ggaatgattt tccaagatcc
    72781 gttgtctgca ttaaatcctc tcatgagaat cgaagaccag atcaaagaag gactttccta
    72841 tcacacaaag atgaatgcag aacagcgtca agctcgtgca ctagaattgc tagaacaagt
    72901 agggattcct aatcctgcga gagttggacg ccaatatccc catgaactat caggcggtat
    72961 gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa cctccaatcg tcattgcaga
    73021 tgaaccgacg acagccctag atgtaaccat ccaagcacag attcttgatt tactgaaaga
    73081 ccttcaggaa gaaacaaaaa cagggatcat cttgatcact catgacttag gagtcgtagc
    73141 agaaatggct gatcgagtgg cagtgatgta tggcggacag ttcgttgaag tagcaggtgt
    73201 aaaagaactg tttgatcatc ctaagcatcc ttatacacgc tctttactga actctatacc
    73261 acaagaagga aatcatgatg cagaactcca tgtgatcgaa ggtgtcgttc cttctctgaa
    73321 aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt ccatggatac cagcaagcga
    73381 tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac cacttggtac gttgctcctg
    73441 ctataagcat ttccacttta gagacgaaaa aggagaggtg tagatgacag aattaatcac
    73501 aatcaaagac ctgaaagttc attaccctat tcgcagtgga ttcttcaatc gagtaacgga
    73561 tcatgtatat gctgtagatg gtgtggattt tattatcgaa aaaggaaaga catatggttt
    73621 agtgggagag tctggctctg gaaaatctac tacgggaaaa gccgttgtgg gattagaaaa
    73681 ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta acgaagcgaa gcaaccgcaa
    73741 aaaaatgggt tataacaagg atgtgcagat gatcttccaa gattcaatgt ccagtttgaa
    73801 tcctaaaaag cgagtgttgg atatcattgc tgaacccatc cgaaattttg aacggttaag
    73861 cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat atcgttggga tgccggaaga
    73921 tgcgctatat aaatatcctc atgaattttc aggcggacaa cgtcaacgtc taggagtagc
    73981 ccgtgctgtt gctaccaatc caaaactgat cgtagccgat gaacctgtat ctgctctgga
    74041 tctatctgtt caagcgcaag tattgaattt catgaaacga atccagcaag aatacggcct
    74101 cagctattta ttcatttcac atgatttagg tgtagtaaaa cacatgtgcg acaatatcgc
    74161 aattatgtac aaaggtcgat ttgtagaaat cggtacaaga gaagacattt ataatgaccc
    74221 gcgacatatc tatacgaaac gtctgctttc agctattccg caaatcgatg tagaaaatag
    74281 ggaaagccac aaagaaaatc gacgaagagt agaacaagag tatatccaaa accaaaaaga
    74341 atactatgat gcgactggtc gagtctacga tttgcgtacg atcacaacta cacacaaagt
    74401 ggcgttgaaa gatggaggtg caagctaatg tggaaaacga ttctgcgacg tgttttattg
    74461 atgatcccgc aagttattat tttaagtgtt ctgatcttct tattagccca agcgatgccg
    74521 ggggatccat ttaccggttt gatcaatcca aatcaggatc cggcagtgat cgaacagatg
    74581 cgacaagcag ctggcttgaa tgacccatgg tatgtccagt acttccgttg gatcggaaat
    74641 gctttgcaag gcgattttgg tcaaagtttc ttatacaaac gctctgttgc tgacttgatc
    74701 ggcgaacgga tcatcaacac tttatatcta tcgatcttga cagttgtcct tacttatttg
    74761 attgctgtgc ctctggggat gcttgctggc cggtatcaaa attcaatctt ggataagatt
    74821 gtcgtaatct acaacttctt tagttttgct gttcctttat ttatcttcgg cttgatcatg
    74881 ctatttgttt ttggttatcg tttaggctgg ttcccaacaa gtggatcaca aacactaggt
    74941 ttgcaaggtg gatttatcac tcaatggata gaccgtttga aatatattct gttaccatca
    75001 attacccaag catttttggc gactgccgtc acaatccaat atctgcgaag tgaagtaatc
    75061 gattcgaaat cgctcgattt tgtcagaaca gcccgttcca aaggggtacc gacgaataaa
    75121 gtattcagtc gacatatttt ccgaaatgca gcgttgccga tggcttctca aatggggtat
    75181 gaaatcactt cgttgattgc tggttctgta gttatcgaaa agatttttgg ttatccggga
    75241 gtcggaaaac tatttattga ttccatcggc caacgggact ataccgtgat cacatcctta
    75301 gtattgattt taggaatcgc gacgctagtg gggacattac tttcagatat catcatgagt
    75361 atcgttgacc cgcgtattcg gattcaataa aaccaatcag aaaggagaat ggatcgatga
    75421 gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc tatggggata cgaatgattg
    75481 ctcgagaatt taaaaaagat aaaattgcta ttttttcatt aggtttgcta gtggttttat
    75541 tattagtgat ctttatcggt gcgatgctga ccgatcaaga caaagtgatg tatgttagta
    75601 tcttcgacaa atacgctgca ccaggaacag tttcgacaca aggacaaaag ttcattctgg
    75661 gagcagatga aggcggacgt gatgtattag gacaattgat cataggtgct agaaactctg
    75721 ttacgatcgg atttgcgatc acgatcctta cttcgatcat cggggttgga ttagggatca
    75781 tctctggcta ctacggaggg atcattgaca acatcttgat gcggatcgtt gattttatca
    75841 tgattctacc gatcatgctg atcattatcg tcttcgtatc gattatttcc agatacaatg
    75901 tctggtcctt tatattcatc atgagtgcat tttattgggt agctaaagcc cgattattcc
    75961 gaagcaagac attatctgaa gcaagaagag attatgtcag tgcctcaaaa acaatgggaa
    76021 ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa tctaagttca ttaatcatta
    76081 ctaatttgac gatgaacttt gcggcaaaca tcggtatcga gacaactttg actttcttag
    76141 gtttcggctt gccggcaaat gtacctagtt taggtacatt gatcggttat gcaagtaacg
    76201 gagaagtctt agtgaatcgg caatggatct ggttacccgc atcaatcctt attttagttt
    76261 tgatgttgag tatcaattat gttggacaag cattcaagcg ttctgcagat gcgcgccaac
    76321 ggttaggcta gtatagaagc gaagggggaa ataggaatga agaaaacgat ttttggattt
    76381 gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg gcggaggtac agatacctct
    76441 ggaaacaact ctggaggcaa cggcaataac aaagaggaat taacttttcc aattgcaaca
    76501 aaaaataatg atgatgcaat cgaagacggc gaattagaag ctgcggtcgc aacggacagt
    76561 cagtttaaag gattgttcca gtgggagttt taccaagatt catatgatgc agcttttatg
    76621 gctccttctc atgaaccgct atttgcaaac gatgacgatt tcagaatcac agacgacgga
    76681 gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga caatcaaagt aaaagacaac
    76741 gtcaaatggt cagatggtga agatgtaacg gcggacgatg tgattttccc ttacgaaatc
    76801 attgggaata aagattacac tggtatccgt tatgacgaca ctttccgtaa catcgtaggt
    76861 atggaagaat atcatgatgg aagtgccgac acaatctccg gaatcaaaaa aatagacgac
    76921 aaaacagttg aaatcgaata taaagaagta aacccaagca tgcttcaatc gggtggtggt
    76981 atctggtcat atgcagcacc aaaacatacg ttagaaggtg tagcaatcaa agatatggaa
    77041 tcaagcgatc aagtacgtaa aaatccagtg acttttggcc cttattacat gagtaatatc
    77101 gttgcaggag aatcagtaga atacttgcca aacgagcact actggaatgg tacgcctaaa
    77161 ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg caactgaagc attgaactct
    77221 aaattatatg atatgatttt ccaaatgcca acagatactt acgataccta taaagaaatt
    77281 gctggctata caaacttagg ccgtgaacaa acttcttata cttatctagg attcaagtta
    77341 ggtaaatgga atgcagatac aaagagtgtg gaatacaatc cagattcaaa aatggctgat
    77401 aaatcattac gtcaagcaat gggctatgca ttagataata atgcagtagg tgaacgtttc
    77461 tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc cagtattcca gtcataccat
    77521 gatgatgaga tgaaaggatt cacacaagat ctagacaaag cgaaaaaact attagatgat
    77581 gctggctaca aagatgtgga tgacgatggt ttaagagaag acaaagatgg aaataaacta
    77641 acaatcaact ttgcttcgat gtccggtggg gaaacagcgc aaccattggc agattactat
    77701 atccaacaat ggaaagaaat tggtttggat gtccaataca caacaggtcg tctgatcgaa
    77761 ttcaattctt tctatgataa attagaaaac gatgatcctg aaattgatgt ttaccaagct
    77821 gcttggaata caggaactga tccaaatcca agtggactat ggggaccaaa tgctgcgttc
    77881 aactacactc gttatgaatc agaagaaaat acaaaattga tcaacgatat cagttcaagc
    77941 aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa aatggcaaca atatgcattt
    78001 gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag tattgccagt caacgaccgt
    78061 gtcaaagact gggattggtc ttatgatgta ccaaacccat gggcaaatgt ttctgttaca
    78121 gcagattcac gttcataatc actaaaaatg accgaaaaag ggcgatgtcc tttttcggtt
    78181 ttttgatatt tttctgttta tttctctaat attcaggtca aggcgctgat ttcatgactt
    78241 ctccaataaa cggtgttcaa agtccagttt ctcggtatta agtcaaattt atgcaaaaat
    78301 atggaaagcc attttcacaa aattttttct tcatactcga aactaaacga atttttcaca
    78361 acttctcgtc aatcactagg attattaaag ctttacttac cttttgaccg aaccatttca
    78421 aatttgacaa aaaaccagta taataaggaa gtatcgaaaa aatatccata aaaggaatgt
    78481 ggaaaatgga caaccagctg acaaaagaac taaaagaaaa ctataacatc gtttttcacg
    78541 atctaaattt gcttgaacaa gcttttaccc attcatccta tgtgaatgag catcgcaatc
    78601 tgcaattatc ggataatgag cgacttgaat ttttaggaga tgccgtttta gaactgatgg
    78661 tttctcagta tttattccgt ttatatcctc atttgccaga aggaaaattg acaaaaacac
    78721 gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc caaagaatgt cactttgatc
    78781 aatatgtttt gttgggcaag ggagaagaga attcaggagg acgtacgcga ccagcattgc
    78841 tttgcgacct attcgaagct tttttaggcg cgttatatct tgaccaggga ttcgacacga
    78901 cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa agcaggtgct ttttcacatg
    78961 agatggatca taaaacaaaa ctacaagaag tcttgcaaaa atcaggtgat gtatcaatcg
    79021 aataccgatt gatcaatgaa gaaggtccag ctcatgaacg agtattttgg atcgaagttt
    79081 atgtagatga tcaattgatt ggcactggac aagggaaatc gaaaaaatta gcagaacaag
    79141 ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt gagggaaagc tttgtatttg
    79201 aaacgaattg aaatagccgg ttttaaatca tttgcagaca agacagtcat tgattttgaa
    79261 aatagcgtca cagcagtggt tggaccaaat ggcagcggaa aaagcaatat tacagaggct
    79321 atccgctggg tattaggaga acaatctgct aaaagtctgc gaggcggaaa aatgccggat
    79381 atcatctttg ccggttccga tacccgtaag cagctgaata ttgcagaagt cacagtgatt
    79441 ttagacaata gtgatcatta tctgccattg gagtacaatg agatcagtgt aacccgccgt
    79501 tatcgacgga ctggggaaag cgagtttttc atcaataaac aaagctgcag attaaaagat
    79561 atccaagaat tgttcttaga ttctggatta ggaaaagaat cgttctcaat catttctcaa
    79621 ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc gtcgtgggat ctttgaagaa
    79681 gcagctggtg tcttgaaata caagcagcgg aaaaagaaag cagaacagaa gctttttgaa
    79741 acagaagaca acctcagccg cgtccaagac atcatccacg aattggaaga acagttaact
    79801 cctttggccg cccagagtga ggcagcaaag gagtttttac ggctaaaaga aacactgact
    79861 caaaccgatg tctctttgat ggttgctgaa atcaagacag caaaaaaaga ttgggacaac
    79921 aaacaagcac agcttgcgaa attcaatcta gaattaggca aactatctga gtcgatccaa
    79981 gaacaagaat ccattttggc gaagcagcgt aaagaaaatg cgcaagccga tcgtctgatc
    80041 gaaaaaaatc agcaagtatt attagatctt tcggaaaaac tgaagcagac agaaggacaa
    80101 aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa gctcgcaaga atatcaaact
    80161 tcattagcag aagcacaaaa aaaggttaaa cattttgaaa agcttcaaga aagcttgatg
    80221 aaagcagcag cagaaaaaga aacagagatc caaaaagctg aagcaaatct cataaaaaca
    80281 cagcaagaat tagaaaaata ccaaaaatca acgaaagaat tattggcaga attaagagat
    80341 caatatgttg atttgatgca agaacaagca gctgtaggaa acgaactgaa gtatctagaa
    80401 cgtcaatata tacaagaaac agcaaaaagc aagcagacgt tagccaagca atcggaagta
    80461 gaagcatcag tagaccgatt gatcttacaa aaagaagaat tgacacaaaa gcaggcgcag
    80521 ctaaaatcat ctttaactga aacaaaagag aagttagaaa tgatccaaca aaacgggaaa
    80581 aagttccaag aagcattagc aaaagaacag cctaaaatgt atcaattaat gaatcaagtc
    80641 cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc aagaaaacta ttttggtttt
    80701 taccaagggg ttcgattggt cttgcagcat aaacagcagc tttcgggtat tgtcggagca
    80761 gtggctgaac tgatcgatgt tcctgcagat ttcacgttag ctatcgaaac agctttaggt
    80821 ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg ctcggcaagc catcacgtat
    80881 ttgaaacagc aaagaggagg aagagcaaca ttccttccac tgacgacaat caaaccaaga
    80941 caattaccgg ctcatatatt gacacaagca gcagctgtag aagggtttat agggattgcc
    81001 agtgaacaag tcagttatcc cgatcaaatc caaactgtgg ttcaaaacct gctaggaacg
    81061 atccttttag ccaaagactt aactagtgcc aatgcaatcg cgcaaacgat ccgctatcaa
    81121 tatcgagtgg tttccttaga aggtgatgtg atgaatgccg gaggatccat gacaggtgga
    81181 gcgaataaac gaggaaacca aggcagtttg tttgtacaaa atcaagaatt gaaacagttg
    81241 actagtgaat ttgaagaagc agataaacaa ctccaagcac aagaaaaaaa agttcaggag
    81301 ctgcaacaag aaacagctcg tttagccgaa gaacaagaag ttttgcgtac acgaggcgaa
    81361 caattacgtt ttgaagaaca agaagcgaca aatcagctac aaaacatcat aaatgaactt
    81421 gaacgttttg aaaaagaaaa gcaaatctca acttttgaga cacgtgaact gcagcagttt
    81481 atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca aacaaacaga tcttgaatcg
    81541 caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc aagaaagcga ccagatggaa
    81601 gccagaagag cacaagtaca aagtcaaaaa gcacaagaac aagcagatct tgctgtcttg
    81661 aaagagcagt ttaatcatct gcagatccag ctccgcggtg cccgagtcca aaaagcagag
    81721 gcaaccgaac gtcaagaagc gatagaaaag cagttggcga cattgacagc agacttttct
    81781 gatcatgaag tcacagaaga aagtttggaa aaacaaatta acgaattatc tgctcagcga
    81841 gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc gagatagaag gcaaaaggag
    81901 atcgataagc ttgaagcagt cttggcagag cgtaatcgtg agcaaaaagc acgactgtcg
    81961 gaacaatcca aattagaagt ccaaaaagac cgagctgaaa tgattttaga taatcatttg
    82021 acctatctgc agtcagaata tcagctgaca tttgagaaag cttcccaaga ctatcaagaa
    82081 acaaccgata tcgaagacag tagaacaaag gtttcatcct taaaagaaca gattgaaaaa
    82141 ctgggaccag taaacttaaa ttcaatcgaa caatacgaac aagtcagtga aagacataca
    82201 ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa accaattgtt tgaaacgatg
    82261 gatgagatgg atgatgaagt gcggacaaga ttcaaagaag tatttgaagc tatccgtcaa
    82321 gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta aagctgaatt agtactgacg
    82381 gaaccaactg atttgctgaa aacaggtatt gagattgaag tacaacctcc tggcaaaaaa
    82441 ctgcaaagtc taagtttgct ttctggagga gaacgagcac ttacagccat cgcgttgctc
    82501 ttttccatta tccgtgtctg tcctgttccg ttttgtatct tagatgaggt agaagcagcg
    82561 ttagatgaag ccaacgtgaa acgttttggt cgttacttga gcgatttcca agatgacaca
    82621 caatttatcg tagtcacaca ccgcaaagga acgatggtcg cagcagatgt actgtacgga
    82681 gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg tacggatgga agatatcaat
    82741 gaagaggcga aaatcaacga aacgaaagtg taggaacgaa aatgatcaaa ttagtagcaa
    82801 tcgatttgga cggtacatta ttaaatgaac aaaagctgat ttcagatgag aataaacaag
    82861 cattagcaca agcaaaacag caaggggtca agatcgttct atgtacagga cgccccttag
    82921 ctgcgatggc gcattatctg caagaattag gactggtaga tgaaggtgac tacagcatca
    82981 ctttcaacgg cggtttggta caaaaaaatg atactggtga aatcatggaa aagaaagtga
    83041 tggaagtatc agatatccaa cgcttataca aactggctca gcaattggat ctgccactag
    83101 atgttttgtc tgacaatgtg gttttacagc tgcctagtgc cccaaggaag caatccttgt
    83161 acaatgtgtt gaataagctg ctgcaattcc aaccagcgga tataagcgat attacagatg
    83221 aatttgtgct taataaggca gtaatcgctt atgaccaaga agaattagat cctaaaatca
    83281 aagaaatacc agcagaattc catgaaatgt atgagatcat caaaacaaga agtatgcttt
    83341 tggaatttat gccaaaaggt gttacaaaag cttatggtat ttctttattg gcaaaagatc
    83401 ttggtttgaa acaagaagaa atcatggcga tcggtgatga ggaaaatgat ttaccgatga
    83461 tccaatatgc tggactaggc gtagcgatgg agaatgctgt gcctttcgtc aaagaagcag
    83521 cagatttcgt gacagccagc aatgaagaaa atggcgtagc caaagtgatc caaaaatttg
    83581 tattagagta gggggagtca aatgggattt tttgataaaa tcaagcgtgc ttttactggc
    83641 gaagagaaaa cagaagaagt tgaagtacag gagaagtacg acaagggttt agaaaagacg
    83701 cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca attttcgaac agtcgatgaa
    83761 gacttttttg aagaattaga agaaacactt atcggtgcag atgtaggttt tgaaacagcg
    83821 atacgaatca ccgaagcatt acgtcaagaa gtgaaactca gaaatgcgaa aaaatcggca
    83881 gaagtccaaa atgcgatcat cgagaaactt gtggatctct atgaagcgga aggaatcaat
    83941 gaagtaaatg aactaaatat ccaagaagac ggactaacag ttattttgtt tgtcggtgtt
    84001 aatggtgtag ggaaaacaac aagtattggt aaacttgccc atcagttcaa aaacgaaggt
    84061 aaaaaagtat tgatggcagc agcagatacc ttccgcgctg gagcaatcga ccagttagtt
    84121 gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca atgcaggagg cgatccagca
    84181 gctgtcgtat tcgatgcttt ggaaagagca aagacagagc aggcagatgt tttactagtt
    84241 gatactgcag gccgactgca aaataaagtg aacttgatga acgaattaga aaaaataaaa
    84301 cgagtaatcc agcgggaatt accagaagca ccccaagaaa cacttcttgt attagatgca
    84361 accactggtc aaaacgcgat ggttcaagca aaacaattca aagaaacaac agatgtgacc
    84421 ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg gtatcgtact tgctatccgt
    84481 aatgaattgc atttaccagt gaaattggtc ggtcttggtg aaggaatcga tgacttggag
    84541 ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag gattactaaa agaagaataa
    84601 cccatgtcta aaaagcagga gctgtgacaa aagttgcagc tccttgtttg aatgattgtt
    84661 tttaacatag ctgtgttttt gatgccttca tttttatact tatttgtaag cggttctcaa
    84721 acaatttcgt tctttttctt agactttttg attataatta gattcatatg aattggaggt
    84781 cacttaatga tgaattttaa gcaattatta ttgcatgtca atgcgcgccc ttttatcgac
    84841 caagctcgat ttggtataga acgggaagga cagcgggttg atcttgcagg aaatctagca
    84901 aaaaccgatc atccagcaat ctttggcgat cgatcctatc acccctatat ccaaacagat
    84961 tttagcgaaa cacaaacaga gatgatcacc cctgttaccg attctattcc cgaattattt
    85021 cagtatctcg ctgctgttta tgatgtgact gctcgttcta taccgaaaga agagatgatc
    85081 tggccattaa gtatgccacc tgccttaccg gaaaaagacg aagagatcat tattgcaaaa
    85141 ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag caaaagaata cgggaagcga
    85201 aaacagatgg taagcggtat tcatttcaat tttgaatttg gcgatgagtt gctaagaaca
    85261 ttgttcagcc atcaggaaga atttcaagat ttttccgaat tcaaaacaga actttatttg
    85321 aaaacagcga gaaactttat gcgctatcgc tggatgatca cttatttatt cggtgcttca
    85381 ccaatgagtg agaagaacta ctttttagat gaatcacatc cgcaagaacc tgttcgcagt
    85441 attcgcaaca gtgcgctggg ctatacgaat catccaaatg tgaaagtttc ctatgcttct
    85501 atgaaacagt atttagcaga tatcgagcga atgatcgaag aagggaaact ttcggaggag
    85561 aaagaatttt atacaccgct tcgtttccga ggcggaaaga aagtcgcaga tttagcaaca
    85621 acaggtgttc gttatattga attgcggaat atcgatttga atccttatgc aagattgggt
    85681 atcaatccag agcaagttcg gttcttacaa ttattcctga tgtacatgtt atggacagaa
    85741 gaaaaagaag actgtgacca atgggtagca gaaggtacga ctcgaaataa caaagtagca
    85801 ctagaacaac catcagatca aacagaattt catcaagaag gtagagaaat tcttgaagga
    85861 atgaagcaaa tgctggttga attggattgg ttggattctc tttatttagt agaggaagca
    85921 ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga aactctatca agaagcacag
    85981 ctatcgagtc agcaagaagt tgctgtggca ttgggacatc aatattataa agaaagccat
    86041 gaacgtccct atcagttggc cggttttcgc gaaatggaac tttctactca gatatttatg
    86101 ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag atgagtcgga tcaatttttg
    86161 cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg caaacatgac aagtaaggac
    86221 agctatatcg tcccacttat catggaaaac aaaacagtaa cgaaaaaagt cttaaaagaa
    86281 gctgggttcc gggtaccagg aggcgcagaa ttttcatcca tggaagaagc ggtaaaagct
    86341 tatccgagat ttgccgagca ggcatttgtg atcaaaccta aatcaaccaa ttacgggtta
    86401 ggtatcacga ttttcaagga aggagctagt ctggaagatt atcaagcagg tttagccatt
    86461 gcttttcgtg aagacagttc ggttttagta gaagaattta tgccgggaac ggaatatcgt
    86521 ttctttgtga tcgacggaga agtccaagcc atcatgttgc gagtccctgc taatgttatt
    86581 ggtgacagta tccgaacagt gaaagaactt gttgaagaaa aaaatagtga ccctttgcgt
    86641 ggaacgaatc atcgtgcacc tttagaattg atccaattag gtgaattaga acaattgatg
    86701 ttgaaagaac aagggttgac gatcgaatca gttccccaag ccaatcaaat tgtttatcta
    86761 agggagaact caaatatcag tacaggtggt gattcgatcg atatgactga tgaattttct
    86821 gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac taggagctaa gattagtggt
    86881 atcgatttga ttataccaga taaagaaatc gatcctacaa ctgataaaaa agcatatggg
    86941 atcatcgaag caaatttcaa tccagccatg catatgcatg tttatccttt tgcaggaaaa
    87001 ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc ctgaagtatt ttaaaagaaa
    87061 aagcttttga cagattgtcc tatttgatgt caatctgatc aaaagctttt tttgcatgta
    87121 aaaatttatg tgttttttcg ttttaaaata aacgatccca gaagcttttt ttcttttttg
    87181 gtttttcttt ttcagctggc gaagagtttt cttctgggta ttttttttcg atatcaatca
    87241 caggttcatt tactgcttct tttgctgtta agagcaatcc gaattcctca ggatttgcag
    87301 tgacgtaatc gttgactaca gtgaaacggc tattgttttt cgttgctagc tggatatatt
    87361 ggttttggac agaaaggggt agagccccat tcaagagtat ggaagcatct ggatgttttt
    87421 tgagttcttt taaaaagttt tctttgtttt ttggttggat catttcagca acagtcatac
    87481 taagatagca gcgttccctg aatgtcccta aatatttatg ctgttcttca gggttcacta
    87541 aaggtgtacc ataaagtccc ttatccaaat ggctttttac atcatcttgt gccataaaaa
    87601 ataccctcct tcttctcttt gtctttctta cgattatagc atattcccaa taatacctaa
    87661 aacatatgaa aaagcggttg cttttgttca acgattcact taaaataaga atgaaaatca
    87721 ttctcaatta gaaaggtgga ttggatgcgc tacggacgac tagtagcatt attagttatt
    87781 ttaagtagta tttcattgtt catcggagta tcgaatgtac aattgtcaga actgctccag
    87841 ttagatgggc aaagcttaca aatcttgcta gtgactcgtt tgccacgaac gatttgtttg
    87901 atccttgtgg gagcgaccag tagtatttgt gggttgatca tgcaacattt gacccaaaat
    87961 aaatttgttt caccaacgac tgcgggcacg atggatagtg cgcgtttagg tattttagtg
    88021 gctatgattt tcctacctgg tgcatccttg attgtccgat ccttgacagc attttgcttt
    88081 gcttttgcag gaacattgct ttttttatcc cttacgcgat tgttcctcca gaaaaatcaa
    88141 ttgatgcttc cgttgattgg agtcatgtta gggaatatca ttggttcagt tgctactttt
    88201 tttgcttatc aattccagtt ggtacaaaat atgacttcat ggcttcaagg gaattttgcg
    88261 actgtgatac gaggaaatta tgagttattg tatgctgttg ttccattgtt gctcttggtt
    88321 tggctatttg cttaccgatt tacgatcatt ggtctgggcg aatcgtttgc agtaaatctg
    88381 ggaatagatt accagaagat gcagttttta ggcattggct tagtatcatt ggctagtgca
    88441 gtcatgttga tcatggtagg aagcattcct tttatcggag tgatcattcc gaatcttgtc
    88501 tctagaatat atggagatca agtgcacaaa acaattggcg taactgcttt agcaggtagt
    88561 ttgttcttag tattttgcga tcttgtcgct cgcgtgttga tttttcctta tgaaatacca
    88621 gtcagtgtga tcgttggaat catcggtggg gctatcttcc tttatcttct gataagggga
    88681 cgacgatatg cttaaaaaaa agccatctat ttttattggt atgcttgttc ttgttttatt
    88741 tgttacagga atgtacttga cgatccatac atatggaaac tggcattttg catgtgcatt
    88801 gaggagtaag aaaatttttg catttatcct tgtctcgcta gctgtcagca gtgccacaat
    88861 cagctttcag acaattacgc ataaccagtt tttgactcct tcagtattgg gacttgagtc
    88921 gttatatgtc cttgtccaaa cggtcctttt cttctttatc ggaggagtga cgatgcttca
    88981 gcagacaggt acagtttttt tcttattgaa cgttgggctg atggtcgggc tgagtctatt
    89041 gttatttttc tttcttttga aaaaaatgag agcgaatctt tttttattac tgatgtcagg
    89101 gatgatttta ggtacgcttt ttggtagtgt cagtaccttt ttacaagtca tcatggatcc
    89161 gaatgaatat gatttgcttc aaggcagatt atttgcaagc tttggcaata tccagagtca
    89221 gtatcttttg cctgcttctt tgatcattat cggctgctgg tacctgttat ttcgatatcg
    89281 acatgtgcta gacgttttcc atctcggaaa tgaacaagca gtaaacctcg ggatagacac
    89341 agatcgtttt gaatttttga ttttatgttg tgtcagtctt ttgacaggga catcaacggc
    89401 tcttgtgggt ccagttactt ttttagggtt tattgtcgca aatatcagtt atcgtgtctt
    89461 ttctacttat cgtcatggtc agctatttat cggaagcttt ctggtagcta tgctgtttct
    89521 gacaggagga cagctcgcag tagagcagat tttcggctgg aatacaacag tgagtgtcgt
    89581 cgttgaattt gtcggaggaa tttattttgt cacaaaattg attcgcgaaa ggaagagtat
    89641 cctatgattg atttacaaaa ggtcaataaa ctgtaccatg gaaaatcagt ggttaaagat
    89701 gtacagttaa cgattcctga aaagaagttg actgctttta tcggtccaaa tggtgctgga
    89761 aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa aagatacagg tgaaatctat
    89821 ttagaccata acgaagtaaa ggcttggaaa tccaatgaat tagccaaaaa attatcgatc
    89881 ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga aagaattagt agaatttgga
    89941 cgatttcctt atacgaaagg aaaattgacg acaaaagacg aggaaatcgt tcaggaatca
    90001 ctggaacacc ttgggttaga agaaatagcg gatcaatcga ttgacactct ttcaggcggt
    90061 caactccaac gtgcgtatat tgcaatggtg ctagcgcaag acacggatta tattttactg
    90121 gatgaacctt tgaacaatct agatatgaat tttgcggttc aaatcatgca gattttaaaa
    90181 aatttagtac aagaaatcgg gaaaacaatt gttattgttc ttcatgatat caactttgct
    90241 gcaagttatg cagacgaaat tgttgcaatg aaagatggac agttatttac gcaaggaacg
    90301 acccaagaaa tgataaaaaa agatgtattg gatgaattat acgaaatgga catacggatt
    90361 tgtgagattg aaggccgcag attctgtctt tatttctaaa actaacatta ggagagaaga
    90421 gatgaaaaaa ttagtagtag gtatcttgat tctagcatca tttggtttag cagcatgtgg
    90481 aaatagcaac aacaccagtc aggcagacac aaaaaaaagc agcacacaaa ctgaaactac
    90541 attgacgata acagatagta atggagacca aatcgaggtg ccaaataatc cagaaaaagt
    90601 cgtcgtattc gacaatggtt ctttagatac gatggatgct cttggtgttg gagataaggt
    90661 agttggagca gctacaagca gccttcctga gtatctttca tcctataaaa aagtagaatc
    90721 agcaggtgga ataaaagaac cagacttaga aaaaattaat cagcttcagc cagatctaat
    90781 catcatttct ggccgacaaa gagattttca aaaagatcta agtcaaattg ctccgaccat
    90841 tttcctttct ttagatgcga aaaatccatg ggaatctttc cagcaaaatg tcactgcttt
    90901 aggggagatc tttggtaagc aagaagaagc taaaactcaa ttagaggaat tatctagtgc
    90961 aatcgatcag acgaaaaaga aagcagaagc tactgacaaa aaagcactag tcacacttgt
    91021 gaatgaaggg caattatcag cctacggatc tggttctaga ttcggtttca tccatgattt
    91081 atttggcttt gaacaagcag atgatcaaat cgaagcatcc actcacggtc aaagtgtttc
    91141 ttatgaatat gtgctggaaa aaaatccgga tatcttattt gtagtagaca gaacaaaagc
    91201 tattggtgga gacgacagca aagatgatat ttctgccaat gaactggtag cacaaacgaa
    91261 tgctggtaaa aatcagcaga tcatctccct tgaaccagat gtctggtatt taagcggggg
    91321 cggtttagaa tcaatgaaac tgatgatcga agatgtgaat caagcattta aatagcataa
    91381 ataacagagg attaaactct catactatgt aacaataatg tttcttacat tcttaaatag
    91441 caagagccta tcctcaaaga agttatcaaa aaccatccgt aaaatcgtat tgatgatttt
    91501 acggatggtt tttatttatt tgagaaatct tttttcaacg tgaattcatt atctacatca
    91561 tacgggttga ttctagaatg gggagtggca aaaaatagtg tgatccattt tttcagcatc
    91621 aagatcgcct cctttgattt gaatcaaagg tacaaagcga aacttagata aaacttaaat
    91681 ttagatattt ttattttgta ccgatctctt ctttaaacga tgttccatct gctgcttctc
    91741 ggcaataag
//
LOCUS       DACGLI010000004        77530 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.004, whole genome shotgun sequence.
ACCESSION   DACGLI010000004 DACGLI010000000
VERSION     DACGLI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.004"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(270..1766)
                     /gene="lysS"
                     /locus_tag="IXT22_000297"
     CDS             complement(270..1766)
                     /gene="lysS"
                     /locus_tag="IXT22_000297"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAQ4861695.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="IXT22_000298"
     CDS             complement(1877..2881)
                     /gene="dusB"
                     /locus_tag="IXT22_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAQ4861696.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="IXT22_000299"
     CDS             complement(2882..3769)
                     /gene="hslO"
                     /locus_tag="IXT22_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAQ4861697.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="IXT22_000300"
     CDS             complement(3986..6097)
                     /gene="hflB"
                     /locus_tag="IXT22_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAQ4861698.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="IXT22_000301"
     CDS             complement(6187..6732)
                     /gene="hpt"
                     /locus_tag="IXT22_000301"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAQ4861699.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="IXT22_000302"
     CDS             complement(6732..8177)
                     /gene="tilS"
                     /locus_tag="IXT22_000302"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAQ4861700.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8297..8767)
                     /locus_tag="IXT22_000303"
     CDS             complement(8297..8767)
                     /locus_tag="IXT22_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAQ4861701.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8813..9238)
                     /locus_tag="IXT22_000304"
     CDS             complement(8813..9238)
                     /locus_tag="IXT22_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAQ4861702.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9305..9574)
                     /locus_tag="IXT22_000305"
     CDS             complement(9305..9574)
                     /locus_tag="IXT22_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAQ4861703.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9585..11180)
                     /locus_tag="IXT22_000306"
     CDS             complement(9585..11180)
                     /locus_tag="IXT22_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4861704.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="IXT22_000307"
     CDS             complement(11195..14716)
                     /gene="mfd"
                     /locus_tag="IXT22_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAQ4861705.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14733..15293)
                     /locus_tag="IXT22_000308"
     CDS             complement(14733..15293)
                     /locus_tag="IXT22_000308"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAQ4861706.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15646..16620
                     /locus_tag="IXT22_000309"
     CDS             15646..16620
                     /locus_tag="IXT22_000309"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4861707.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16790..18190
                     /locus_tag="IXT22_000310"
     CDS             16790..18190
                     /locus_tag="IXT22_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAQ4861708.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18268..18990)
                     /locus_tag="IXT22_000311"
     CDS             complement(18268..18990)
                     /locus_tag="IXT22_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4861709.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19069..19575)
                     /locus_tag="IXT22_000312"
     CDS             complement(19069..19575)
                     /locus_tag="IXT22_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4861710.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19698..21497
                     /locus_tag="IXT22_000313"
     CDS             19698..21497
                     /locus_tag="IXT22_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAQ4861711.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21565..23139)
                     /locus_tag="IXT22_000314"
     CDS             complement(21565..23139)
                     /locus_tag="IXT22_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861712.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="IXT22_000315"
     CDS             complement(23394..23903)
                     /gene="mreD"
                     /locus_tag="IXT22_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAQ4861713.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="IXT22_000316"
     CDS             complement(23907..24761)
                     /gene="mreC"
                     /locus_tag="IXT22_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAQ4861714.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24916..25554)
                     /locus_tag="IXT22_000317"
     CDS             complement(24916..25554)
                     /locus_tag="IXT22_000317"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAQ4861715.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25555..26205)
                     /locus_tag="IXT22_000318"
     CDS             complement(25555..26205)
                     /locus_tag="IXT22_000318"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAQ4861716.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="IXT22_000319"
     CDS             complement(26218..27117)
                     /gene="rsgA"
                     /locus_tag="IXT22_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAQ4861717.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="IXT22_000320"
     CDS             complement(27282..29351)
                     /gene="pknB"
                     /locus_tag="IXT22_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAQ4861718.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29348..30088)
                     /locus_tag="IXT22_000321"
     CDS             complement(29348..30088)
                     /locus_tag="IXT22_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAQ4861719.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="IXT22_000322"
     CDS             complement(30101..31459)
                     /gene="rsmB"
                     /locus_tag="IXT22_000322"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAQ4861720.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31459..32397)
                     /locus_tag="IXT22_000323"
     CDS             complement(31459..32397)
                     /locus_tag="IXT22_000323"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAQ4861721.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32390..32881)
                     /gene="def"
                     /locus_tag="IXT22_000324"
     CDS             complement(32390..32881)
                     /gene="def"
                     /locus_tag="IXT22_000324"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4861722.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32896..35304)
                     /gene="priA"
                     /locus_tag="IXT22_000325"
     CDS             complement(32896..35304)
                     /gene="priA"
                     /locus_tag="IXT22_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAQ4861723.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35557..35862)
                     /locus_tag="IXT22_000326"
     CDS             complement(35557..35862)
                     /locus_tag="IXT22_000326"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4861724.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="IXT22_000327"
     CDS             complement(35867..36481)
                     /gene="gmk"
                     /locus_tag="IXT22_000327"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAQ4861725.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36968..37252)
                     /locus_tag="IXT22_000328"
     CDS             complement(36968..37252)
                     /locus_tag="IXT22_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861726.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37270..38160)
                     /locus_tag="IXT22_000329"
     CDS             complement(37270..38160)
                     /locus_tag="IXT22_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAQ4861727.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38180..38398)
                     /locus_tag="IXT22_000330"
     CDS             complement(38180..38398)
                     /locus_tag="IXT22_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861728.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38368..40068)
                     /locus_tag="IXT22_000331"
     CDS             complement(38368..40068)
                     /locus_tag="IXT22_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAQ4861729.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40335..41108
                     /locus_tag="IXT22_000332"
     CDS             40335..41108
                     /locus_tag="IXT22_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861730.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="IXT22_000333"
     CDS             complement(41189..41758)
                     /gene="thiT"
                     /locus_tag="IXT22_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAQ4861731.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41824..41926)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41932..42903)
                     /locus_tag="IXT22_000334"
     CDS             complement(41932..42903)
                     /locus_tag="IXT22_000334"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4861732.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="IXT22_000335"
     CDS             complement(42997..44370)
                     /gene="glmU"
                     /locus_tag="IXT22_000335"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAQ4861733.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44873..45691)
                     /gene="purR"
                     /locus_tag="IXT22_000336"
     CDS             complement(44873..45691)
                     /gene="purR"
                     /locus_tag="IXT22_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAQ4861734.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45858..46682)
                     /locus_tag="IXT22_000337"
     CDS             complement(45858..46682)
                     /locus_tag="IXT22_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4861735.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46655..47335)
                     /locus_tag="IXT22_000338"
     CDS             complement(46655..47335)
                     /locus_tag="IXT22_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861736.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47358..48296)
                     /locus_tag="IXT22_000339"
     CDS             complement(47358..48296)
                     /locus_tag="IXT22_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861737.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48541..49392)
                     /locus_tag="IXT22_000340"
     CDS             complement(48541..49392)
                     /locus_tag="IXT22_000340"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAQ4861738.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="IXT22_000341"
     CDS             complement(49546..52119)
                     /gene="mprF"
                     /locus_tag="IXT22_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4861739.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52260..53066
                     /gene="proC"
                     /locus_tag="IXT22_000342"
     CDS             52260..53066
                     /gene="proC"
                     /locus_tag="IXT22_000342"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAQ4861740.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53145..54701)
                     /gene="rny"
                     /locus_tag="IXT22_000343"
     CDS             complement(53145..54701)
                     /gene="rny"
                     /locus_tag="IXT22_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAQ4861741.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55112..56161)
                     /gene="recA"
                     /locus_tag="IXT22_000344"
     CDS             complement(55112..56161)
                     /gene="recA"
                     /locus_tag="IXT22_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAQ4861742.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56270..57511)
                     /locus_tag="IXT22_000345"
     CDS             complement(56270..57511)
                     /locus_tag="IXT22_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAQ4861743.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="IXT22_000346"
     CDS             complement(57751..58329)
                     /gene="pgsA"
                     /locus_tag="IXT22_000346"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAQ4861744.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58538..59422)
                     /locus_tag="IXT22_000347"
     CDS             complement(58538..59422)
                     /locus_tag="IXT22_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861745.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(60200..61486)
                     /locus_tag="IXT22_000348"
     CDS             complement(60200..61486)
                     /locus_tag="IXT22_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4861746.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61479..62747)
                     /locus_tag="IXT22_000349"
     CDS             complement(61479..62747)
                     /locus_tag="IXT22_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4861747.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            62999..63460
                     /gene="mscL"
                     /locus_tag="IXT22_000350"
     CDS             62999..63460
                     /gene="mscL"
                     /locus_tag="IXT22_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAQ4861748.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63519..63965)
                     /locus_tag="IXT22_000351"
     CDS             complement(63519..63965)
                     /locus_tag="IXT22_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4861749.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64058..64303)
                     /locus_tag="IXT22_000352"
     CDS             complement(64058..64303)
                     /locus_tag="IXT22_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861750.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64418..64996)
                     /locus_tag="IXT22_000353"
     CDS             complement(64418..64996)
                     /locus_tag="IXT22_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4861751.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65073..65603)
                     /locus_tag="IXT22_000354"
     CDS             complement(65073..65603)
                     /locus_tag="IXT22_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAQ4861752.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="IXT22_000355"
     CDS             complement(65607..66467)
                     /gene="rlmB"
                     /locus_tag="IXT22_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAQ4861753.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66460..66855)
                     /locus_tag="IXT22_000356"
     CDS             complement(66460..66855)
                     /locus_tag="IXT22_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4861754.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(66852..68264)
                     /locus_tag="IXT22_000357"
     CDS             complement(66852..68264)
                     /locus_tag="IXT22_000357"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAQ4861755.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="IXT22_000358"
     CDS             complement(68261..68797)
                     /gene="cysE"
                     /locus_tag="IXT22_000358"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAQ4861756.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(69119..70579)
                     /locus_tag="IXT22_000359"
     CDS             complement(69119..70579)
                     /locus_tag="IXT22_000359"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAQ4861757.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70749..71906)
                     /locus_tag="IXT22_000360"
     CDS             complement(70749..71906)
                     /locus_tag="IXT22_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAQ4861758.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(71940..73310)
                     /gene="radA"
                     /locus_tag="IXT22_000361"
     CDS             complement(71940..73310)
                     /gene="radA"
                     /locus_tag="IXT22_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAQ4861759.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73373..73900)
                     /locus_tag="IXT22_000362"
     CDS             complement(73373..73900)
                     /locus_tag="IXT22_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAQ4861760.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74130..74936
                     /gene="proB"
                     /locus_tag="IXT22_000363"
     CDS             74130..74936
                     /gene="proB"
                     /locus_tag="IXT22_000363"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAQ4861761.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            74933..76180
                     /locus_tag="IXT22_000364"
     CDS             74933..76180
                     /locus_tag="IXT22_000364"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAQ4861762.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76256..76600
                     /locus_tag="IXT22_000365"
     CDS             76256..76600
                     /locus_tag="IXT22_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861763.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76717..77043)
                     /locus_tag="IXT22_000366"
     CDS             complement(76717..77043)
                     /locus_tag="IXT22_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861764.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
BASE COUNT        21323 a        16833 c        13944 g        25430 t
ORIGIN      
        1 ttttgttatg tttttgaata aatattttct tctgtctttt ggacaagtaa taatatacca
       61 actaaattta gcttggtcaa cgaatttttt gtattttttc aagttttttt caataaacga
      121 ttattcataa cttttctttc tttatcgttc gttttcgtct tctttaatgt ctagaatagt
      181 cggcattagc ttttgaactt tcgttattat ttattccttt ctacacagca aaagctgcct
      241 aaggaattcc ttagacagct tttattcgat tatctcattg ttgggaatag caaaacatcc
      301 cgaattgatt gtgcatcagt tagcaacatt actaatctgt cgatcccgat gcctagacca
      361 ccagttggcg gcataccgta ttctaaggct tccaagaagt cttcgtctac accgtgagct
      421 tcgtcatttc ctagttcacg ttctttttct tgcgcttcga atctttctct ttgatcaatt
      481 ggatcgttca gttctgtaaa ggcattagca aattcgcgcc ccactatgaa tagttcgaat
      541 cgatctgtga atcgaggatc ttctggattt ttcttcgcta aaggcgaaac ttcgactgga
      601 tgtccgtata caaacgtcgg ttgtgtcaat gtttcttcaa caaatgtttc aaagaattca
      661 ttgataacat gtccgacacc catagcttcg gttacttcta cattgtgttt ttcggctaaa
      721 gctaatgctt cttccaatgt catttcttgc cagaagtcta caccagtttg ttctttgatt
      781 gcatctacca tatggatgcg tttaaagtca ctttctaagt cgacagcttg tccatcatat
      841 gtgatttttg ctgttcctag tactttttca gctgcgttac ggataatacc ttctgtcaga
      901 ttcattacat cattgaaatc agtatatgct gtgtatgctt ctaacatcgt aaattctgga
      961 ttatgtgtag tatcaattcc ttcattacgg aaaacgcggc cgatttcata aactttttcc
     1021 attccgccaa caattagtcg ttttaaatga agttctagcg caatacgcaa atataaatca
     1081 atgtccagtg cattatgatg cgtgataaat gggcgtgcgg cagctccacc tgcctcattg
     1141 tgcaatactg gtgtttctac ttcaatatag ccattgccat ctaaatagcg acggatttcg
     1201 ctgataattt ggcttcgttt cataaatcgg tcaaagcttt cgcgattact gattaaatcc
     1261 aagtagcgtt gtctgtagcg ttgttcaata ttcgttaagc catggtattt atctggcagt
     1321 ggacgaagtg cttttgacaa aatcgtgatt tctgaagctt tgatagaaac ttcgcctgtg
     1381 tctgttttca tgatttgtcc agttacacca aagaaatctc caaggtctgc atgtttgaat
     1441 acttcatagg cctcatcacc tacttggtct tttcttacat aaatttgaat ttggccttca
     1501 cgatcttgta gatgcgcaaa tccagctttc ccttttcctc ggcgagtcat catacgacca
     1561 gctacactag cggtcaatcc catttctgct agttcttctt ttgttcttgg atcaaatagt
     1621 tcatgcaatt cttctgagtt gtgcgtgcgt tcaaatcgtt ttccaaatgg atcgattcca
     1681 tcttcacgca attgttccat tttttgacga cgtacaagca tttgatcatt taaatcttct
     1741 acttgatgtt gttgttcctg tgtcacaaaa gttcctccat tctcatgtta atctctttcc
     1801 tataatgcca atgaaacaca aaaaaagcaa gccgaacttg gaatttcggc ttgaaaattc
     1861 acgaaaaact tagaaatcac aacgtttgtt tcaatagtac tttttccgct ttttctacaa
     1921 attgatccag caggtcattg atttcttgct gtttttctgt ctgattgatt gctactttca
     1981 ctttcgctgc tcgaggaatc ccttttaaat aataagccgc atgtgttctg aattctctac
     2041 aagctacttt ttctcctttg agatctgcta agcgttgtaa atgaagttta gctgtagcaa
     2101 ttttttcggc tggtgttggt tcaggaatca gttcccctgt ttcgagataa tgctgtgtgc
     2161 ggtgaatcat ccatggattg cccagcgctg cacgaccaat catcacaccg tctgcaccga
     2221 catagtcaag catccatttt gcatcttctg gcgttttgac atccccgttc cccataaatg
     2281 gaatcgtcaa atgttttttc acttctttca atacttccca gtccgctttt ccttcataca
     2341 tctgaacccg tgtacgtcca tgcatagcga tggcacttgc tccagctgat tgtgctgcta
     2401 atgcattttc tacagcaaag acgtgctctt catcccaacc aatacgcatc ttgattgtta
     2461 ctgggatatt tactgctgaa gaaacagctt ggaccatttc gtatactttc tcaggatcta
     2521 aaagccattt tgctcctgct tctgctttga ttactttatt tactggacag cccatattga
     2581 tatctattat atcggcagct gtgttttctt cgacaaattg agcagcttca actagactat
     2641 ctttatttcc gccaaatatc tgtaaactta atggatgttc tgtttcttca atgtggagca
     2701 tctctaaagt ttttttgttt ctgaaatgaa taccttggtc actgatcatt tcacatacga
     2761 ctaagcccgc accaaattct ttgacagtga ctcgaaatgc tgaatttgtt attccagcca
     2821 tcggtgcaac aacgacacga ttagggattt ccacattgcc aattttccat gtgtgttcca
     2881 cttaaatccc tcctaaggct tctttcttca atccatctaa ttcttcttcg ctatacttgt
     2941 atttgttatt acagaaagaa caaaccgctt ctgcaccgtg atcttcgtct atcattgctt
     3001 ggatttcttc tgcacctaac gcgataattg cttctgcaaa tttttctttt gaacagtcac
     3061 atttgaattg aacaggcatt ttttccaaaa tgttcaattc ttctgtacca agcaatcctt
     3121 tcaatatttc ttctggtgtc tgtccttcat ctaagagggt agagattctt ggtgtcgttt
     3181 ttaattgttc ttcgatcttg ctgattgttt cttcatcggc acctggcatg atttggatca
     3241 tgaatcctcc cgccgtcttg atgctgtcgt cagtattgac caatacactc agtccaacag
     3301 ctgaagggat ttgttctgag atagcaagat agtaagtaaa atcttcagcg atttctccag
     3361 aaacaatcgg cgtttgccca gaaaaaggtt cttttaatcc taagtctttt gtgacagtaa
     3421 acattccttg tgttccaact gctccccgca catcgatttt accttcacta tttagaggaa
     3481 gactgagatg cggatttttg atgtaacctt tcacatctcc ctttccattt gcatctacta
     3541 caattcctgt tgctggacca tcgccttgga ttcgaacagt tagtttgtct tctcctttga
     3601 gcgtcgcacc aagtagcaga ctaccgacca atgtccgtcc caaagcagct gaggaggtgt
     3661 gccaagtatc atgacgtctt tgtgcctccg ctacggtatt tgttgcttga acggcgtatg
     3721 ctcggacgaa tccgtcgtga gcaagtgcct taaccaaata atctttcatt tgttatgtac
     3781 tcctttttcc gtttttaaac tcatagtgaa tcatactagc aactactgct tttttcaact
     3841 ttggaatgct tcttttaaaa ataattcaga atcatctaga aaacaggaca tcaccctatt
     3901 tacaacttaa ataaagaaat ctcccgaaaa ccggtttttg ttccggtttt cgggagtcat
     3961 atcagatcaa ttgacctata tttttttatt tgtattgatc gtctgaatga ttatcttctg
     4021 attgttgaga atctgaatca tgttctgctt tattttcctc attcagttca tgttttgctt
     4081 cttcaaaatc acgtttttct tccgcttgtt tttcagcgtc tttttcttcc aaagcacgtt
     4141 ttgcttcttc aaaagttttc gcttcttttt cgcttggata atcatttgac tcagtacctt
     4201 caggcatcac accgtgttca aacaatgact tgattgcttt ggcatccaat gtttcgaatt
     4261 ccaaaagttt ttcagcaatc agtttatgct gtgcacgatg agcttcgatg atttctcgag
     4321 ctttatcatg agcttccatc aagatttttc gtacttcttg atcaatctcg aaagcgactt
     4381 gttccgagta agcttttgtt tgaccatagt cgcggccaac aaacacttga tggtttcctt
     4441 catattgaac aggacctaaa cgatcactca ttccatattc tgttaccatg cttcgtgcta
     4501 gagctgtcgc ttgctcaaag tcattggaag caccagttga ttggacattg aagatgattt
     4561 cttcagctgt acgtccacca agtaagccta cgatttgttc aaacatatct tctttcgtca
     4621 tcaagaactg atcttctttt ggtaaagcga tcatatatcc gccggcgcgt ccgcgaggga
     4681 tgatcgttac tttgtggacg acccgagcgc gactcaatac taatccgaca atcgtatgac
     4741 cagcttcgtg ataagcaacc atttcgcgtt cttttttgct gattacgcga tcttttttag
     4801 ctggacctgc aatcacgcga tcttccgctt catcgatatc agaagcatcg attttctttt
     4861 tatttcttct agcagctact aacgctgctt cattcaagac attttctaaa tctgctccgg
     4921 caaaacctgg tgtctgttga gccacaactt tcaagtcaac gtcatctgcc atcggtttat
     4981 tccgtgcatg gactcgcaag attgcttcac gaccttttac atctggacgt ccaactaaaa
     5041 tctggcggtc aaaacggcct ggacgtagta acgctgggtc tagtacatca gaacggttgg
     5101 ttgcagcaat gacgattact ccttcatttc cgtcgaagcc atccatttct acaagcaatt
     5161 ggttcaatgt ttgttcgcgt tcatcatgtc cgccgcccat accggcacca cgttgacgac
     5221 ctaccgcatc aatttcatca atgaaaatga tagctggtgc gtttttcttc gctgtttcaa
     5281 acaaatcacg aacacgactt gctccaacac cgacaaacat ttctacgaaa tcagaacccg
     5341 agatcgagta aaacggtact ccagcttctc cggcaacagc ttttgctaat aaggttttac
     5401 ctgttcctgg aggtccttct aaaagtacac ctgccgggat acgggcacct aattcaacaa
     5461 atcggcgagg atctttcaga aattcaacaa cttcaactag ttcttgtttt tcttcttccg
     5521 cacccgctac atcagaaaaa cgtacgcgat tagctttttt gtctgcttct ttggcttttg
     5581 atttaccaaa gttcatgaca cggccgccac cgccaccgcc gccgccttgt tgtcccatca
     5641 tcatgtaaaa gaaaaagatg atgattacga ttggcaagaa gctaagcaat agggaaaccc
     5701 atataccgct gcttgattct tcttttactg ttgtagcaac tttgttttct tttgccagtt
     5761 ctgttacttg gctcaatgtt gtatcatttg gcaaaatgat tgttgtgaaa tgggtagtag
     5821 tcgtatctgt tgaacctaag atagctaacc caccgctgtt agcgacggtc tgctgttctt
     5881 tgtattcacc agtgatctta tatacaccat ttgcaggctg cacttcaaat tctttgatct
     5941 tgcctgcttg tagttgttct gtgaattttg agtactcgat atctgacgat cgctggccgt
     6001 tattaccaaa aatgaaataa acgaccatta ccatcgctaa gattacgagg acataataca
     6061 aggcattttt catcatgccg ttgttctttt tgttcatagt tgccctccct aagcgtcaat
     6121 ttaatttaac agttttttat caatcctgac cattctattg taccataatt taattgagat
     6181 acagcattaa tttgattgat aaacactagg tttcaataca ccgatgtacg gaaggttacg
     6241 atatgcttct gcataatcca agccataacc gaccacaaat tcatttggta cgttgaagcc
     6301 aacataatct gcttcgatat ttactactct tccttcaggt ttgtcaagta gtgtaacaat
     6361 tttgactgat tttgctttgc ggtatttgaa aagatccact aaataagcaa gtgttcttcc
     6421 gctgtcaatg atatcttcaa cgatcaacag atcgcgacct tctacattcg tatctaagtc
     6481 tttgacgatt tttacttccc ctgacgagac tgttgcattc ccgtagcttg aaacatccat
     6541 gaaatccaat tccaaatacg tatcgataga acgaacgata tctgccatga atggtaccgc
     6601 tccttttaag acacctacta ctaggggatt ggtgttttgg taaatttctg ttaactcttt
     6661 gcctagttct ttgcaacgaa cttgtatctc ttcttgtgag atcaaaattc tctcaatatc
     6721 cttttccaac atcaggttct ccttccaatt gcttcttttt gatatttgta aagaagtatg
     6781 tagtgtattt tatcagtttc ttcacgaata ctcaaatatg aaaaggcaaa aggtatcaag
     6841 ctatatatat ttcttttggc atctgtaatg atccaagcat gctgcctttg tgaattaggt
     6901 actttctgat cgataaaata tctagatact ttttttgtga gattctctgt taatttaatg
     6961 cggtctcctg cttttctttt ttcgacatac agttgcacat cagcaggaat ccaaatgtca
     7021 tgagaaaata gagaccatga atctgttgct ttgatgtccc ctgcattttc aggtttgacc
     7081 agaccaatcc attctgtttc attcaaatat attccttgtt ctggaatcag caacaagcgc
     7141 tggtcttctg tctggctagt tgcttgtttt tcttttttag agagtacaac aaaatgatac
     7201 tctcttttca gtatccaatt attgccaata ctgagttgcc attggctttt tttctgttgc
     7261 cactggtcta aaatcgactc catttgttgt tctttcaaaa taattcctgt ttttgagaat
     7321 gctttgtcga aaaaggagta aaaaaaatag tatcgttcag catctgtcat ttcttcaatc
     7381 atttctgcag aaaatcgaaa ttgttcctcc cactgttcga cttccttttc gatcaactgt
     7441 cccatatatt tttgaatgac ttggtctgcc cattggatct gttgcgaaaa ttgctggaaa
     7501 tgtctcaacg cctgtgtatt ttcttgtttc aattgaggaa ctaccaaatg acgaagccga
     7561 tttctctgga tatctaacaa ttggtttgtc tgatcctcaa agtaaacaag ctgcgattcc
     7621 gctgcataag tatataggtc ttctttgcta aaactcagca acggacgaat cagtctgccc
     7681 gtagcaaatg gttgtacttc tttgattcca gaaaaagtat ttaactgtcc cccacgaacg
     7741 attttcatta acaccgtctc gatttgatca tctccgtgat gagcagtcat caacgtgtca
     7801 tattgtcctt cttccatcac gcgagtgaat tcttgataac gaaagttacg agcttctgtt
     7861 tctatggcgg atttggctgg atcttcccaa atacttacat ataaagggag attcttctct
     7921 tcacaatatg agcgaagata ggcagcttct tctgctgatt cttctcttaa ttggtgattg
     7981 atgtggacga tacctaaaga aaaaccgatt tggcgttgca cttgtaaaag taaatggagc
     8041 aaaaccatcg aatcaacacc acctgatacc gctgctaaaa ttctcgatcc ttgttgccag
     8101 aatccttgtt cattcccgtg ccgaataaat gactgctgta atagcggtgc ttttttcccg
     8161 cctttttcaa cgttcatcct ttccacaccc tttcttccta aaaaaaagag agcgggaaaa
     8221 cgtctaaaac gacaattaac ctgccctctg ttgatactat gacccaaata gtcgcactat
     8281 cattatttgc ggctttttag ctgcgacgtc cgccacggcc accgcgcttt ccttctgtgt
     8341 ttcgcttcaa tgaagataag cggtcatcgc tatctttcaa aaatgaactc atcaatgaat
     8401 cgaagtcttc tttttgagct gaaggttgac tgcgagaaaa agattttttc tgtgctggac
     8461 gatttcggtt gtcacgggga tctttttgtt gatatttttt aggacggctt tcttctccag
     8521 attcagcagg ttgttcctgc gctttccgga tagatagtcc gatttttcca tcatcattta
     8581 ctgaaataac tttaactgtt acttcatctc ctacacttaa aacatcatgg atgtctttta
     8641 catagccatt tgacacttcg ctaatatgaa ctagacccgt ttttccagca cctagatcaa
     8701 taaacgcacc aaaatttgtg attcctgata cttttccttg cagttttgct cctacctcga
     8761 ttgacataaa aaaaatgttc ctcctaatta tttccctttt ttatattcct gcttattttg
     8821 cagttgtaga actagttgat tgatctgttt catttgtcga gctgtctgta tttgattcta
     8881 atataggata aactttttca ccgtcttttg agtaaaagaa tttgcttctg gcaagtttag
     8941 ctacatactc atcatctttc agcaatgaaa catcttggtg cagctgatca acgtctgcgt
     9001 tgacttcttt catttcagta tttgcttcga ctctcaattc gttcaattga tgcatccttt
     9061 gcatgtcatg gaaaatctgc acacctatta tcgcgaaaat gaccaaagca ccaacaaaaa
     9121 ttgcagccag tctgcgtctt cgaaaaatca gttgacgttg ttgttgctga aattcagcat
     9181 actttttctt tgcatattcc gtatctagcg cagcgatttt attgcttttt ttcgtcactt
     9241 ggattcgctc caatcttttt gattgtcttt ttcattatac caatatcgtg aaagcttgtc
     9301 taatctattt ctctagtgtt tctgtgcgat tttcagaaat aatttcgtac attttttgtg
     9361 catcttcttt tttggttgat tcatgtaatt ccgtaatttt cacttccaac gttttgttgc
     9421 caaactggac tttcaaaata tcgcctactt tgacatcact ggaagatttc gccaatttac
     9481 cgttgatttg aattcttcct ttatcagcta cttcttttgc tactgatcgt cttttgatga
     9541 ttcgggaaat ttttaaaaat ttatctaatc gcatatctta ttcctcactt tttaattttt
     9601 ttatttaatc gcaggatttt cttaccaaaa ggcaacatta gccattctcg tactgtaaac
     9661 agacgaagac gaatcactgc ataaatgaac acagaagccc cgatcccaac tcctatcacg
     9721 ctgacaaaaa aagcagtgga acgatgagtt acaggaccaa atactatatt caatacacca
     9781 taatacagca gcagtactac tgtcatacaa agaaggctga acatcaactt ccgtccaaaa
     9841 tgccgttctt tccaaaaagc atttagctct tttgtttcaa ttcgaacaaa ataccaaagc
     9901 gtcacaccta atcctaaaag ggtagacagg cttgcacctg ctgttcctaa taaaccggtc
     9961 agaaaagaag tagtcaatcc ttttaccaat agtccccatc ctgcgccttt taaagaaggg
    10021 cgaaacgagt tcttgctttg agcaatactt tgataagctt ggatgactgc agtgaaagca
    10081 atggaaaaaa caaataatac aagcgctgca tttcccgcat aatctttaaa caacgcataa
    10141 ttgatataag ggagcagcaa ggctaatccc aaagacgcag ctaatgctaa agcggtcgtc
    10201 aatctaagat agattttggc tgtctgtaaa aactgacgat agatccggtt ggtcaaatga
    10261 cgagtcaacg caggcaggaa tgtcgcactt aatgcagtgg caatcactaa acctaattgt
    10321 actaaaggct gacctcgatc atagacccct tttgctatct tcgcaccgta ttctgacagt
    10381 ccgtaaactt ccaaagcatt ttttacaaag aaagagtcga tcagctggaa aaagataagc
    10441 aatccactat aaatcgaaac cagtccgcct tctaccagaa aacgccggat caagggcttt
    10501 gacggctgtt tgaacaatgg aaaccgtcgg aagcttaacg ctcctccatg aatcttttgt
    10561 tcatagtagt gaaggatccc atatgcgcat aaaccgccaa aaacagctcc actcattgct
    10621 gccgtccctg tttggtacac cgtccatcca agctttctaa aagcaaacgc actacagaca
    10681 atcacaaaaa cacgaacgaa ctgctcaact acttgagaaa cagcagttgg ttccatcaag
    10741 aatcttcctt ggaaattccc tcgataaaaa gatagaccag gcatcagcaa aaaggtaaag
    10801 gaaactactt ggatcagcgg tttcaattgt atgtctccca tcatccaagc aatccagctg
    10861 ctaaatgcaa agacaaacaa ccacaaaaag acacctgtcc aaaatactaa gggataaaga
    10921 ttttgcaaag cttgctttcg ctcgaaagga ttctttcttt ctgcaacgta ctttgatatg
    10981 aactgcggaa gaccggataa agctaaagtc attgctatcc cataaattgg ataaacttgc
    11041 tgataaacat aaaaaccttc gtcgccgact aagttttgga ggggaattcg gtaaagggca
    11101 cttaatactt ttgctatgaa agaagcaatc gtcaatacaa atgctccttg catgacgcgc
    11161 cgcatttctt tatgatccaa atcattgctc cttcctacgc tgacagatat ttttgctcac
    11221 gcaacgcttt gacaaacttt tggatttcct gaagccatac tgcttcttcc atttggttgg
    11281 ggatcgtcaa gcgtatcacc atctgttctt tttcaacgcc tagactggct tttagttttg
    11341 tcgctgtcag tgcttcgaat aactgttcca cactatagcg ttttgttcca actttactta
    11401 gagtaaagac tatatgcgcc tcctgtttcc ttatcgtttc taggagcgct cgatcgccat
    11461 ccattttgat ctgcccaatt gtcaagagat gtgctacttc ttctggatat tctccaaaac
    11521 ggtcgagcag atcatcttct agttcatcta gcatttcttg cgaatcaagt tcacgaattc
    11581 gtttatagat ctcgattttc tgccgttgat ctgccacgta tgtttcaggt agatacgcat
    11641 cgacaccgag gtcgatctca acagtggtct tctccacttg actattcttt ccttgtttac
    11701 gagaaacagc ttcgcttagc atttgagaat acatatcgaa accgactgca tcaataaatc
    11761 catgctgctg agcacctaag agattacctg caccgcgaat ggaaagatcc cgcatcgcaa
    11821 tcttgaatcc agatcccagt tctgtaaaat ctttgattgc ctgaagacgt ttttcactga
    11881 cttcgttaag gatcttctgc tgctcataca taaagtaagc atatgcgaca cggctgcttc
    11941 ttcctacccg ccctcgcaat tggtataacg tggataatcc catataatca gcgttctcaa
    12001 cgaacaacgt atttgcgttc gggatatcta ctcctgtttc aatgatggtt gtagtgacaa
    12061 gaacatcata ttgaccttca ataaattcaa aaagcgtatt ttctaattgc gcctctgtca
    12121 tttgcccatg agcataaccg atccgtgctt ccggaacgag ttcttggatt tcttctactt
    12181 tttgttcgat cgtttctacc cgattatata aatagaatac ttgtccacct cgtcccattt
    12241 ctcgatggat tgcttcgcga atagccccag gatttttttc cataacatac gtttggatcg
    12301 gataacgatt cgcaggcggt gtttcgatta ctgaaagatc ccgcacgcct aacatcgaca
    12361 tatgcaaagt tctcggaatc ggtgttgcag tcagagtcaa aacatccact tgtgcacgta
    12421 actgtttcaa tcgttcctta tgttttacac caaaacgttg ttcttcgtca atgatcagta
    12481 gacccaaatc gctaaattca atatcttttg acaaaattcg gtgggttcct acaacaatat
    12541 caacttgacc tgtacgcagt tgttcgatgg tttctttttg ttgctttctt gttctgaaac
    12601 gacttaatag cccgatattt acggggaaac cttcaaatct ttccagcatc gtttcatagt
    12661 gctgctgtgc caagatcgtt gttggaacta aaaaggctac ttgtttgctt tcctttatcg
    12721 ctttaaaggc cgctcgaagc gctacttctg ttttcccata accaacatca cctacgagta
    12781 gtcgatccat tggtttttct ttttccatat cccgtttgat ctccgctgca cttctcaact
    12841 ggtcatcagt ttcagagtag gggaaggcat tttcgaattc tttttggtag gcgtcatcag
    12901 gtccaaaagc atatcctttt tctgactctc ttgcggcata taatttgatt agatcgtcag
    12961 cgatatcctc gatttttgaa gagacttttc gcttggtttt cgtccattca cttccgccta
    13021 gcttattgat gcgaggcgct ttggcttcag aggcgacata tttttggatc agattcagtt
    13081 gagtaacagg aataaacagt ttgtcgtcgt tttgatacaa aatagtcata tagtcttggt
    13141 gaacgccatc tacttctagc gtttccatcc caatgtattt cccgatacca tgattggcat
    13201 ggacaacgta atctcctgct tttaactcat tatagctttt caatcgctct gcgtttgtta
    13261 ctgtttgacg tctcgtttgt tttttcgtcg ttttttggaa aatttctttt tctgtgatag
    13321 ctactatttt ttcttgagga agttcaaaac cagcctgcaa agctccttca actaattgta
    13381 cctgtcctct gatcaatgca tttttttctg tttctactac taatatgtct tcatctcgaa
    13441 gcatttgttc tgctttgcgt attctgtcct ttgtcggaat aaagatcaca acagtctgtt
    13501 tttgcttgcg ccaacggtcc atttctgttt tcagcaatgg catttgtccg aagaactgtt
    13561 gcatcgtccg atattgaaaa ttatggattg cttggaaacg aagatttccc atcccttttt
    13621 ggaagagtga gaaaaaggtt gtggtgaact tttccttctg cacgattttt tgtatatctg
    13681 ctgaaaatgt ctgctcagaa aacacccgca attcgctgat tttttgagtc tgccattctg
    13741 ccgcttccct ttcgatttcc cgatttgttt ccatgattcg ctgataatca tcaacgacta
    13801 gtaaactatt tgaagggaaa taatccaaga tcgtcacaga ttcttggtaa agaagatctg
    13861 agtagaattt tgcttcttct gtcgggacac ctgcttgcca gcttgaagtc agctgaccga
    13921 agtaatcttg caaaaactcg cggtctgctt cttctgtggt cgcagcaagc cgtttttcta
    13981 gcattttttg catttgctct attccatgtt ctagatcctc tggtccgtag acttgttcac
    14041 tcgttgggga aacccagatt tcttccgttt tttcgattga gcgttgtgtt tctgcttcaa
    14101 aataccgcat agaatctatc tctacatcaa atagttctac acgaacagga taggttgtcg
    14161 ttaacgggta aatatcgata atgcttcctc gaatactgaa ttctcccggt tttgcgacca
    14221 tctcttctcg tacatagccc atcaaagtca attggcgagg aagattttcc acgtctatct
    14281 catcaccaat atgccaattc aattgcgcct gtagccaagt tttcttattc ggcagtcgtt
    14341 tgtgcaaaga tgcgactggc aacaaataga tacctgcttt tttttcttga agtgcgttaa
    14401 gcgttgcaac tctctcgcct cgcgcttctg gagaagaaaa ggccatttca gcagaaagca
    14461 cttcatccac tggaaataaa tggatctgat cttgcggaat cacatgttgc agatcttctg
    14521 ctaactgatt cgcataatac aaatttggca tcagaataat catgttttta tttgttttct
    14581 taaacgctcg agcaaataga agtgttttcg ctgagcccgc taatcctgtg attagttgtc
    14641 taggcatttt ttcttctaaa ttgctgaccc attcttttac ttgcggatct tttccgacta
    14701 attgaataat atccattcct tttcctcctt cctcaattga atcgattcat cgcatccacg
    14761 aacgaatgcc cttctatgag atattcgact gctttaacag attgacacat gctttcttct
    14821 atcaaaggct gattttcttt gctgaaagga ctaagcacat gctggactac tgtttttttc
    14881 ccttctggcc tgccgattcc caccttgatt cgatcaaaga cattcgtatt caaatgggaa
    14941 ataatacttt tgataccgtt atgcccgccg gcacttccct tttgacggag ccggattttt
    15001 cccactgcca gatccaaatc atcgtagatt acgactaatt cctctggata aatcccaaaa
    15061 taagtcatta gtgggccgac tgcacgacca gattcattca tgaatgtttg tggtttgact
    15121 aaaaggatct tttctccatt atgaaaaaat tcggcaactt ctgcttcgaa cggatttttt
    15181 ttgaaagtag cttgatgctc gcgtgcaatt ttatccacga ccataaagcc gatattgtgt
    15241 tttgtatatt ggtatttggt acctgggttt cctaacccga cgatcatttt catttttgtt
    15301 ttccacctaa ttctaaaaag cagcacaaaa ggctggactg ctaattagcg gtccagtcca
    15361 tcgagctttt ttctttttta cacttgtcaa tgcatagtat aacacaaaac aaggcgtttc
    15421 ggctaaaaga gaatcgttaa taaatgataa agaaattaaa aatttcttca aagtttaatg
    15481 aaataattga tatataaaaa tagtgaaata acgcacatgt aagcttttac atataataca
    15541 accttgttat ctgttatatt ttatagccaa atagcgtgac atggggcttg agaaatgtta
    15601 gcataagcat gggaaaaaac aaatcaatgg aaggattgat actaaatgac tgcagctgca
    15661 gaaaaaaaag atcatcaaaa agttattctt gttggagacg gcgccgtagg ttctagctat
    15721 gcctttgctc tagttactca aaatatcgct caagaagtag gtattgtgga tatcaatact
    15781 gctaaaactg aaggagacgc aattgacttg tctcacgctt tggcatttac ttcacctaaa
    15841 aaaatctatt ctgctactta cgcagacgca catgatgctg acttagttgt tattacagct
    15901 ggcgcaccac aaaaaccagg tgaaactcgt ttagacttag taaacaaaaa cctaaaaatc
    15961 aaccgcgatg ttgtcacaca aatcgttgaa tcaggattta acggtatctt tttagttgcc
    16021 gctaacccag tagatatttt gacttactca acttggaaat tctcaggttt ccctaaagaa
    16081 cgcgtaatcg gttcaggtac ctctcttgac tcagctcgtt tccgtcaagc acttgcggaa
    16141 ttagttgacg ttgatgcacg taacgtccat gcttacatct taggtgaaca cggagattca
    16201 gaattcccag tttggtcaca tgcaaatgtt gccggcttgc aaatctatga atgggtaaaa
    16261 aacaacccag aaatcgatga agaagctatg gttaacctat tctttggcgt acgtgacgct
    16321 gcttacacaa ttatcgagaa aaaaggcgct actttctatg gtatcgcagt agcattagca
    16381 cgtatcactc gtgccatctt agatgatgaa aatgctgttc ttcctttatc agtattcatg
    16441 aatggcgaat atggattgaa cgacatctac attggtgcac ctgctgttat caaccgtcaa
    16501 ggtatccaaa aagtaatcga aattccttta agtgacagcg agcaagaccg tatggctgct
    16561 tctgctaagc aattaaaaga aattctagat gaagcttttg ctaaactaga cgctgaataa
    16621 tctttgaaca tgacggaaaa catctattcg gtgttttccg tttttttatt ttatcaccct
    16681 tatggtttct aaattttttc ataaagtaga gataaccttc gtcttttcct ctaaattatg
    16741 ctatcatgag accgttccac cctaaacttt tacttaagga gttgtcgata tgacaagatc
    16801 ttcgcatcga aaaaaatcga aacatgttgc tttgctttca gttcttggtg ttctcttagt
    16861 gctgatcagc ttttatacct atcgcagtac atactacaca aagcattttt tgccgaatac
    16921 agaaataaat ggaataaatg tcagcaatct aacagtcgaa aaagcaaatg aaaaattaaa
    16981 agaagcttat tctgataaaa aactggctat taaagaagat ggaaaagtct ggcaggaagt
    17041 accaaaatcc gagctcggct acaaagatga tttcacttcg gagctttctc cgatcctaaa
    17101 tgaacaaaac ggatggactt ggggaatgac ttatgtctca gcggcagaaa aacaagaaat
    17161 agatcctgtc agtcaaaacc accaaaaact agacactacc gttcagacat tgacaactaa
    17221 gctgactgat ttgaacaaag accggacacc tactactgat gcaacgatcg aaaaagcagg
    17281 tgactctttc gttatcaagc ctgaagtcaa tggaaatacg atcgacgtcg atgctgcggt
    17341 caaacaatta aaaagtgcgg taaactctgg taaagataca attgaattga ctgaattcaa
    17401 agaaaaacca aaagtaacat ctgaagacag ctcactgaaa gaacaactcg catccatgaa
    17461 tgctatcgca aatgtaaaag ctacttacag tataaacggt gagactttcc agatcccatc
    17521 aagtgatatt atgagttggc tgacctacaa tgatggaaaa gtcgatttag atacagaaca
    17581 agtacgtcaa tatgtaacag atttaggcac aaagtataac acaagtacga atgacacaaa
    17641 atttaaaagt acaaaaagag gagaagttac ggtcccagtt ggcacttaca gttggacgat
    17701 ccaaacagac agtgagacag aagcattgaa aaaagcgatt ctggcaggcc aagattttac
    17761 tcgttcaccc attgtgcaag gtggcacaac cgctgatcat ccattgatcg aagatacgta
    17821 tatcgaagtt gatctggaga accagcatat gtggtattac aaagacggaa aagtggccct
    17881 tgaaacagat atcgtttccg gaaagccaac tacacctaca cctgctggag tcttctatgt
    17941 ttggaataaa gaagaagatg caactttaaa aggaacaaat gacgatggaa caccttacga
    18001 gagtccggta aactactgga tgccgattga ctggacaggt gttggtatcc acgattcaga
    18061 ctggcaacct gaatacggtg gagacttatg gaaaacccgc ggttcacacg gctgcatcaa
    18121 caccccacca agtgtaatga aggaattatt cgggatggtc gaaaaaggaa cgcctgtatt
    18181 ggtcttctaa caaaaataat atataaaaag aaagcacccg tacgattggt acaggtgctt
    18241 tctttttatt atctaacaat gtgctactta catttcagca gcagtaaaga cttctgaaac
    18301 atcatcatcg tcttctagct tatctactag acgttccaat tgctcttttt gttcctcatt
    18361 taaatcaatc gtcgtttgtg gaatcatcgt caattctgct tgcgccaaag tgaactcttt
    18421 ttccaactca tctcgtacag cagcaaaatc ttctggtgca gtataaatct cgaatacttc
    18481 aggagaagtt tgcagatctt ctgcccccgc ctctaataca tcctcaaaca tcgtctcttc
    18541 atcaacagtc aacccatcgc gttcaatagc gatatatcct ttgcggtcaa acaagtaact
    18601 gactgaaccc gtttctccca gtgatccacc gtttcgagta aaagctactc ggacatttgt
    18661 cgctgtccga ttacggttat ctgtcaatgc atggactaag attcctactc cacccggacc
    18721 atatccttca tacgtgattt catcgtaatt cgtttcatct acggcactcg tagccttttt
    18781 aatcgcccgt tccacattgt cgttaggcat atttgcagct tttgctttgt ccacaacaag
    18841 ccgcaaagct ggattcatag atggatcagg accgcctgct ttagctgcca tataaatttc
    18901 acgagaaagt ttctgaaaga ctttccctcg ttttgcatct tgggcatttt ttcttccttg
    18961 gatattatgc catttactat gtcctgacat gatttttcct cccttgttct tttgagaata
    19021 cacttctatt ctagtactat ttcacaaaaa aacaaagcca cagccaatct ataaacgctt
    19081 cttgaatgcc gcaaaaagca cacataatat cacagcagtc agagcaccga tcgaatccaa
    19141 catgacatct tggaacatag gtgttcgtcc accggtcatc atctgatgga attcgtccaa
    19201 acctgcgtac cctgttgctg aaagccaagc aaggatcgct gtcagccacc aaatttttag
    19261 cttggggaaa acacctaaaa acaagctgcc tcccaaaata aaataggtac cgaaatgtgc
    19321 gcccttcctt aaaaagaact ctaaaaattt ggcgtagccc agatggttga tactcaccat
    19381 acttccacca taattaaaac gtatacccgc taatgtgtct ttaaatggct gattaggcag
    19441 ccagctttct aatcgcgaaa cttgtgattg ctgtccgtaa gtttgagaag aactgtaaaa
    19501 taagattata acgactatca gtgcgattac taaataaata tttccgtttt tcatttgttt
    19561 ttttgaagaa ttcataagtc acctctgtat tttatcttag actttttttg aagaaacaac
    19621 aatcattttc atagagactt cttccataaa aaagtgctat acttaatttt gtattacaat
    19681 atgaagggag ttttttcatg agttattcat taaattggaa tctagattct attttttccg
    19741 gaggcagtca ttctgatgct ttgaaccaac ggatgaagca attggaagac caaatgaacg
    19801 agtattatca ccgcgtaaca aaatggtcac ctagttctga caatgcagag cagttaaacg
    19861 ctattcttca attgcaagaa acgattacga atggttttac ccaatgcagc agctatatta
    19921 ctgcattgct ttctgccaat gtcaatgatt cagatgcaaa ggtcttatca ggcaagcttt
    19981 acgcaatgct gcctcgtctg caatcagccg aaactgtatt gtcaaagaaa tttgcagaaa
    20041 tatctgacaa tgattggaat cagatgcttt ctcaatcttc gtttgaaaca attgcttttc
    20101 gtttaaacga gattcgtcgt gatggctcac aattattatc agaagctgaa gaaaacatta
    20161 taaatacgct ttctttagat ggtctaaatg cttggagcag tcattatgat acgattgtag
    20221 ccagcatttc gattcccttc gaacaagatg gacaagtagt cgaattatct gctggacaag
    20281 ccttcaataa gatgatgggc gatccagatc caaaagtcag agaaacactt ttcgcagcat
    20341 gggaagaagc ctggaaagaa aaggcacccc tcttcacgga tactttgaat catttagatg
    20401 gttttagact ttctgactat gaacttcatg gtgtcacaga ttttctacaa aaaccattag
    20461 agtacaatcg gttgaagaaa gaaacattgt ctgtcatgtg ggatacaatc cagaaaaaca
    20521 aacaacccct tgttaattac ttgactagaa aagctaatct tttcggtaaa gaaaaaatgg
    20581 aatggcaaga tcaagatgca cctattattt taggcgattt gaaagaaaaa acctttagtt
    20641 ttgacgaagc agcagcattt attatcgaaa actttaacaa attcagtcca aaaatggcta
    20701 aatttgccca atctgctttt gaaaagagct ggatcgaagc agaagatcgt cctgggaaac
    20761 gtcctggtgg ttattgtact gagttaccag aaacaaaaga atcaaggatc tttatgacct
    20821 acagtaattc tgttaatgag gttgcgacac ttgctcatga actaggacat gctttccata
    20881 gcagcacgat gtgggattta ccttctttaa atcgcgaata tgccatgaat gtcgcagaaa
    20941 cagcaagtac attcgcagaa ctgatcgtag ccgatgctac attaaaagtc gcaaaaacaa
    21001 aagaagaaaa aatcaatttg ctagatacaa aactgcaaaa tgctttagct atgttcatga
    21061 atatccattc ccgattcatt tttgaaaatc gattctatga agcacggcaa gaaggattag
    21121 tctcagaaga taagatcaca gagatgatgg ttgaggcgca aaaagaaggc tatcaaggag
    21181 ctttagctac ttaccatcca tatttctggg ctgcaaaatt gcatttcttt attgatgacg
    21241 taccgtttta taacttccca tacacatttg gctacctctt tagtttgggc atctatgctt
    21301 acgccaacca aaagggagca aattttgaag aagaatatat ccatttacta cgcgatactg
    21361 cctcaatgac gacggaagat cttgcgaaga aacatttgaa tgtcgatctt acccaaccag
    21421 atttttggca agcaggtatc gacatggtga ctgaagatat ccaaacgttc atggaattga
    21481 cagaagaatt tatctgattt ctattttatc acaataaaaa aagagttagt ccagaatggg
    21541 ctaactcttt ttgattaatc attcttacat gctgacagca aagtcagggg caaaccattg
    21601 aactgaacca acttttacgc tttcgcctgg ttgaggagca tggatatatt gtcctccgcc
    21661 taaagcaatc gctacgtggt aagttccgcc ttgtgacccc cagaataaca agtctccagc
    21721 ttttgcttga gaaactgaaa tttttgttcc agctgattct tgaggaactg tccaaccacc
    21781 gatgtcacga ccagttactt gcatgtaaac atagcgtgtg aaccctgagc agtcaaagcc
    21841 acttggatct ttaccgcccc aaacatatgg agtaccaata tatttgtaag cttctgctac
    21901 gattgctgca ccattcacac ttccagaagg agctggagca ggtgttacag gttttggttg
    21961 ttcaggtgtt ggtgttggcg ttggagccgg agtactactt cctgtgccgt ttcctgtatc
    22021 aacactttga tctgttgatg gtgttgtagg cgcaggtgtt gttgattctt ctgttgttga
    22081 agattcaggc actgttgttg attcttctgt tgctgaagat tcaggcactg ttgttgattc
    22141 ttctgttgct gaagattcag gcgctgttgt tgattcttct gttgctgaag attcaggcgc
    22201 tgttgattct tctgttgaag attcaggtgt tgttgattct tctgttgctg aagattgtgt
    22261 agctgatgat gattcttcag tcattgaaga ttgtgtagct gatgattctt ctgttgctga
    22321 gctttgtgca gtagatgaag cttgagtagc ttgtgcttca gcctctgctt gttcgcgtgc
    22381 ttctttttca gctttttctt gtgcagcttg ttgacgagct tgttctgcta gacgttgttg
    22441 ttcacgaata cgagcttgct ctgcttcagc ttctgctttt tgacggttca agtcagcttt
    22501 cttgtcttca gcagttgctt gttcagcagc taatgaagtt ttcagtacgt tcaaatcagc
    22561 ttgtttagat aaaagatcgc ctttttgaga ttccaaagca gcttggtttt cagctaattc
    22621 ttttagttta gcatcgtttt cagctttttt gtcttctaca gcttttttat cttgtttttg
    22681 ttgttccatc aagtcgttgt ttgcttttac catcgttgtc attgcttgaa cgcgtccaat
    22741 agcatctgct aatgaatcag cattcaatac agcatcgatg tagtttgagc ttgtgttgct
    22801 tacttgtgct tcgcgtgctt gtttttggat tgtatcttca cgtttttcaa tacgttcttg
    22861 taaatctgca atgtctttta ctaattgtgc agattcttga cgcaatgtat cttgttttgc
    22921 taataggtct tgtgcttgtg tgttgatttc agaaacttgg ctttctaagg catcgatttg
    22981 tgattgtgca tctgcttgtt gatttttcaa gtctgcaatc ttttgatctt gctgttgtat
    23041 ctgagaatca aaatcgtccg ccgcggcagc gatcggtgat gctacggcag tcaaggtcat
    23101 tgaacatacc attactgctg atattaaact ctttttcact cttcattcct ccgactggct
    23161 taatttaata aatatctaaa tatatttaag tctttcttaa cgatataaaa attgtaccat
    23221 agcagtgtgt caacgatata atagttatgt tacaaaaatg tttcaaaaca acttttaaaa
    23281 atgacaaaac tgttcgtttc agaaaatgat catgaaaaag ccgcgttaag tctagcattt
    23341 cttaagataa caacgattct ttttcgcttt cgacctaaaa ataaaaaaag aaattattca
    23401 tcactgaata atttcttaaa gggaaaaatg aataatacaa atataatcat gttcaacagc
    23461 agtgtaggtc ctaaaaacct tgtaataaaa tacgtgttat ttactactgc taatttaaaa
    23521 atcaactgga ccaccatcgt aaacaattca taacccgtga caaagatgat catactgaaa
    23581 aattcagtaa agatgttgac atggataacg tctttcatta catacatcaa ccatacaatt
    23641 aaagggagag ctactgcata gataccgata acgccaatat agtaagcgtc atagatagcc
    23701 ccgagaacaa tcgtggtaat cagtaaataa cgtttttcaa acgccatact gcaacataat
    23761 aatgccaata tcagaaagtg ggcatttgac atataggtgc ctttcgacca ctcccctagc
    23821 attcttgtta aatgaccatc tatcaacatc aaaaagaaca aaacgattgg cagatagtac
    23881 ttcattgttt ctttcttcaa catggactaa tcctccgcta gccgttggac aatcgtcaca
    23941 actgacacgt catacatttc tgcataaggt ttcacataaa cttcccgatc cagcccataa
    24001 ctatctggtt tcgttttaat aaccgtaccg atcggcaagt tagctggaga attccctcca
    24061 agaccggatg tctggacaac atccccttct ttgatatccg tatcaccagt taattgggtc
    24121 accactaagg catggagctt ttcatcatag tttttaagca aaccaaacgc ttcgccatta
    24181 gccgaagata cccgtactgg aaaatgattg gagctttcat tagaggatga cagtaattcg
    24241 attttagacg aagccgtatt gacctcgatc actcggccaa tcaatccttt ttgcgacatg
    24301 actgccatat ttgcttcgat accgtcttta gaacccttgt ctacgatcag catgtcctgc
    24361 caactgtcag gcgaacgagt aatgacattt gccgttactt tttcgtaact agtcagcgtc
    24421 tgattcaact caagttcttt tttcaacgct tcgatttctc tctcgtaatt cttgttttgc
    24481 tgtgaaacgt catcatagct atcgattttt tcttttagcc gctcattttc ggcataagtt
    24541 gaaaaaagat tatggacaga atctactcca tttcgtaccc accgtactgg ggcagagatt
    24601 gttttatcaa ccattgcaac actgtcatta acgatggatt ggaagaaatt gggctttcct
    24661 tcattcgctc gctgcgcagc ggtcacactt agtatcgtca ccacgatgat aacaataacc
    24721 aaggtaataa taatattttt attaggattg aacttcttca caaagacacc tcgaattaat
    24781 tagactcttg tgttcaattt tatcactaaa tgccgtgaaa caaaaggtaa gttgctcctc
    24841 ttaagctttt ttttagcaaa taatagattc tgtcattttt agcctgaaag acaaattttt
    24901 ttatttgttt atggatcaat ctttgctttg aataactgca atcataccat ctgaaaaaga
    24961 aaattctgcg gtatctgaaa gaaattcgtt acttgcataa gatgtcggat attctacttc
    25021 tttattttcc aatacatact tgctgccttt taatgtaaga ttcgagacgg gagtcaagca
    25081 gcaataagct aaatacttca tatctggtat ctgtcttact atatgctctc caggcaaata
    25141 ataagacaaa taattttgac aatctctgat aataagctga tgggcaaagg gtttgaagcg
    25201 aggttccata cctaaccaga gattggctaa aagatgatcc aatcttccgc ccgtagctcc
    25261 aatcaaagtg acttccgctt gcgggtaacg ttcaaatgtt tttaagatac ctaactgtgt
    25321 atctgtatcg tctttttctg caggggaacg ggtatactct ttggcttttg caaatacttc
    25381 cttctgctct tcgttcgaca atgaatcaaa atcacccact gccagatcta ctgggtagcc
    25441 tgcttgaagc aggtacagcg caccacggtc tatcccgaca taggcatcgt atttggacag
    25501 cagagactgc ggccagtttt gcggattacc tccagcagct aataaaattt tcatttagtc
    25561 taatgcctct tttaatcgtt cgatttgtcc gactggattt tcggctccat agatatatga
    25621 tcctgcaacg aagacatccg cccctgcatc tttacagatt tttgctgttt ctggaacgat
    25681 tccgccatct acttcgattg cataagtcca attgttctct ctacgtagat cagcgagttc
    25741 cgtaattttt tctactgttt cttcaataaa gctttgtccg ccgaacccag gattgacagt
    25801 catgactagt acttgatcag ccaaaggcaa aacatgtttg atcatggaga ctggtgttcc
    25861 tggattgata actactccag ctttaactcc taagcttttt gtcatttgaa gtgcccgatg
    25921 aatatgagga gttgcttcga cgtggacagt aatgatatct gctccagctt ttgcaaatgc
    25981 tggaatgtag ttttctggat caacgatcat cagatggacg tctaacggta atttagtaac
    26041 aggacggatt gcctgaacaa tatttggccc taatgtgata tttgggacaa atcggccatc
    26101 cattacatct acgtggatgt aatctgcgcc tcctttttcc actaactcaa tgtctctttg
    26161 taaattggca aaatctgcac tcaaaatgga tggtgctatc ttcattcttg tttcctccta
    26221 ttttcgttta ccttcttttt ttgcatacat tggttttctt ttttcgattt cttgtaagaa
    26281 ttgcaaataa ttgtcgtaac gtgtctgtgc gataccacct gtttctactc tatgttttac
    26341 ttcgcagcca ggttctttag catgcatgca ctctctaaat ttgcaatgga cagaagcttc
    26401 tacaaattca ggaaattgtc tcggcagttc tcctgcttca attgtcaaaa agtcaatcga
    26461 gctaaatcct ggtgtatctg ctactaaccc gccatagata ggaatcagtt ccacatgacg
    26521 tgttgtatgc cgtcctcttc caagtgcatc agaaatctct cctgttgcta aattcagttc
    26581 cggtgatatt tgattcagta gcgtcgattt tcctgctcca gactgaccca taaagaccga
    26641 tagccgttct gggaagtaac ggatcagttc tgtcgtatca cccgtatgat tgggtacaat
    26701 caccggatag cctattttag tataggtttg cttgatctct tcgatttttt ctgggtcgtc
    26761 tgacaagtcg gtctttgtca aaaaaataat cggttcgatc gactcgtatt ccaaggtaac
    26821 tagaaagcgg tcaagtagat tataagaaaa tgcaggctct acgatacttg tgacaatgat
    26881 tccaagatca acatttgtga ctggtgggcg aactaattga ttttttctcg gcaagatttc
    26941 cagaagatag ccgtctgttt gattttcact ctcaaagatc acctgatctc cgacaagcgg
    27001 cgtgattttc cgattccgga aatttcctct tcctcttgtt tgataggtct ctccgtttgc
    27061 gtatacatag taaaaaccgc tgattgcttt tctgatttgt cctttgataa gtgccacctc
    27121 cgtttttgtt tattttacca tacgaagagg aaagtaggtg ttattccatg caaacttctc
    27181 aaagtatatg gcttgaaaat tgatcaaaag agatagaaac acaaaaaaga gaatgcaaca
    27241 aatcaatgtc gcattccctt ctgatatatt ttattcagca cttattttga actttctgag
    27301 gtgctagctg atgaacttgt ggagctggaa gattcttctt ttgaagagtt gcttgtgcta
    27361 ctggagctac ttgagctgct agaactgtct gaagagtctt tttcagaact agaagacgct
    27421 ggatctggtc ctttagagta aattacgttc acaaccattc ctttggtaat tgtcgttcct
    27481 gcccctggta ctgtacgaat cactttatct ttatccaccg tgtttgaata ttcggaagtc
    27541 tcatgcccga tatattctgc accgacacta gctaaataac tttgtgcttc gctttttgta
    27601 tagccggaga tatcattcaa tttaggctct gttccttggc ttacgacaaa attgatgtaa
    27661 gtttcttctg ctacaacttc acccgaggct ggatcctgac tgatgatcga acctgatggt
    27721 acagtgtcgc tatagtcata agtagcacta atattattga tattgaatcc ttgtgtaaca
    27781 agccaattac gaacagtttc gtagttttct cctacatgac tactcaaagt cactgtttct
    27841 ggtcctttgc tgactgtgaa agtaatcgtg tctgttttag gatcgacttc tgtatcttct
    27901 gatggagatt gcgaaatgat cattccgctt tctacctctg aactgaattc ctcttctttt
    27961 tgaatcaagt cagcagaaaa ccctaattct ttcaaacttg cttcggcatc ttcataactt
    28021 ttaccactgt aatcatctaa tttgattttt ttcgtgccgc tactaatata cagagtgact
    28081 tcgcgttttt gcttgactgt cgttcccgct gccgggtctg tcttcactac attaccttct
    28141 tcgattttgt catctgcaat ttcttctgtt tttgttgcta cttctaattt cgcttttgcg
    28201 agtgtttctc tagcagaagc ttcagaaaga tcagaaacat caggaacaac aacttctcct
    28261 cgcccgccag aagcaaagaa tacagctgtt ccgattccta aaacagcaag aatagctaat
    28321 aggatcagcc accatttttt ctgtcctttc tttttaggat caggcagaac ttcttcctcc
    28381 tctggtaagg tttcgttttc tggcttgtct tttggcagag gcatagattt gaatgaatca
    28441 ggcattggtg catcttccgt aaggggtgtg ataacttttg tttcattatc catcacatga
    28501 ggctgccatt tttcttcgtt tgcacgagct ggtgataata ctgtagaaag atcatcagac
    28561 atttcctcgg ctgacttata acggtctgca ggttctttag ccgttgcccg taaaatcacg
    28621 ttttccagtg cttgtggcac atttggatca agtgctttta tagatggaag atcatcttga
    28681 aaatgtttta aagcaattgt tacagcagat tcaccatcaa acggtacgct acccgtcaac
    28741 atctcataaa ggatgatccc taaagcataa atatctgact gcttcgttgc catacttcct
    28801 ctggcctgct caggggacag ataatgaaca gatcctagca tcgtattcgt ctgcgtgatc
    28861 gatgtttcag ataaagcgat agcaatcccg aaatccgtga tttttacaac accttcatta
    28921 tcgatcagta cgttttgggg tttcaaatct cggtggatga tttgatggtt atgagctaaa
    28981 gaaatagcag aaaggatctg ctgcataata tttactgctg tttcataagg aacaggataa
    29041 tgtgtttgga tatatcgttt caagtccatt cctttgacgt attccatcac cagatactgc
    29101 atgttgtctt cttcaccaac atcgtaaaca ctaacaatgt ttggatgaac gagttctgtt
    29161 gctgctaaag cttctctctg aaatcgtcga atcgcagtct ggtcattttg aaagtcaaat
    29221 cgtaagactt taactgctac atcacgatcc aagattaaat cgtgcgccaa aaatacattt
    29281 gccataccac cgctaccgat atttccagtg atttgataac ggccatttaa ttttttgccc
    29341 aactcgatca tacactgtcc tccttatatt cgataagaag aacggtgata ttatccgctc
    29401 cgcctgcttc attggcacga tcaatcagct cagttacttt atgagacaat gggccttctt
    29461 gattgatgat cgttcctatt tcttcttcag acagcatgtt cgtcaagcca tctgaacata
    29521 acagcagtcg atcttttagt tgccaaagat gagtagaaac atctacttcg actgttccag
    29581 gcatgccgac agaacgtgtt aaaatatttt tccttggatg gttcactgcc atttcttcgc
    29641 tgatttctcc tgatttgact agttcattga ctaaagaatg atcctccgtc aattgcatga
    29701 ttttatcttc acgaatcaaa taagctctgc tatccccaac attggcaatc gtgaaccagt
    29761 catctgacag agcggccgct acgattgttg ttcccatacc gttatattcc ggctgttctt
    29821 gtccacgctg ataaatcagc atattttctt cttgaatcga ttgaatgaac cattgggcga
    29881 ttttttcatc gtcaacagct tcttgttttt cccaagcttc gcctagattc gttaccgcca
    29941 tctgactggc aatgtctccg gcacgatgac cacccatccc gtctgctaat acagcaagct
    30001 tgagacctga acggctggta aatacactgg catagtcttg atttgtgtta cgtcgtcttc
    30061 ctacatctga ttgatattca atctgcattt tttcacctca ttactttttg cgcaaacaac
    30121 aaatgaaaaa tccatctgtg taaaactgat gcggatacaa agtcaacatt ttctcttcga
    30181 ttgatgattg tagcatagga ttggtcaaaa catcaatcct ctcaaaatca gggtgtcttt
    30241 ccaagaaagc agaaacaacg tcttggtttt cttcttttaa gatcgtacaa gtgctataag
    30301 tcagaatacc ggaagacttt aaagttggtg cgcagctttc taaaatttcc aattggattt
    30361 ttggtaaatt cgctaattca tccggctgtt ttttataacg aatatctggt tttcgccgaa
    30421 gcagcccaag acctgaacaa ggcgcgtcta ctaaaatccg atcaaactgc tctgcttcga
    30481 actgtttact gacttctcta gcatccatct tttgagcgta gacagcagaa gagacaccta
    30541 gacgtgctgc attatcttca atgagtttga ctttgtgttc gtgtacatct aaagcgacca
    30601 cttctccacc gcatgacgga tctaaaaaag aagcaatatg cgtcgtctta cctccgggtg
    30661 ctgcacaggc atctaagaca tgatgttcag gctcgatttg catagacggc gctacaagca
    30721 tcgaactttc atcttggatc gtcatgacgc catcgtggaa caatgagcta gaagctaaat
    30781 gccctttttt cgctactata ccgtatggac tgacttggct tttttcagct gtgatctctt
    30841 cttcttgcaa aacagtgatg gcctgatctc tggaaagtcg gcgtgtatct actcgggcac
    30901 tagcatggct aggctgatat agcgataaac cgagcttttc agtttcttcg tatccgattt
    30961 gatccaccag tcgtttcgtc atccatagag gcaggctgat tttgacagaa agtctttcga
    31021 taggatcagc aatgccttgc agatctggtg ctccttgacg ctgataattc ctcaagacac
    31081 catttacaaa tttccctgtc ccaggatttc cttttacttt tgcgatttcg accgcctcgt
    31141 ttaaaatagc atgtgcaggg actttatcta aaaattctaa ttggtataca gaaagataaa
    31201 gaagcatctt gacccagtca tccacttttt ttgctttagc gatcaatggt gcaacgtaaa
    31261 attccaatag tcgctgatgg ctaatcgtac catagatcaa ttctgtaaat aaacccacat
    31321 ctttttgatt tagctcgctt tgtttgatca tctcattcaa caaaagattc gagtaggcgc
    31381 cacccttgtt cactcgctct aatgtcagta atgccatata tcgtactgat tttttcattt
    31441 ttttagggat ttttttcatt atttcacctg ctgaccaatc tgaacttgct gaccgcttcc
    31501 gttaaggaaa tcatgtacgg cctgttttcc tttaccagct ggctgtaatt cattgatggc
    31561 taagacggtc tgtttaccgc aagcaatcca tagatttttt ttgtctttcc ggatgatcgt
    31621 accaggtgct ttgtctgtag tttctgccaa tacttcaacc gataataatt tccagcgtat
    31681 gccctcatag gtcgtgaatg caattggcca aggacgcatt ccgcgtactt ggttgtcaat
    31741 ttcttctgca gttttatgcc aatcgattgc ttcttgttcc cgtgtgatgt ttggcgaaaa
    31801 agttgcttct gactcgtctt gaggtactgg tttttgtcca tccaaaatat tgggcaatgt
    31861 ttctagcaat agctttcttc ctaaaaggct aagcttttca aacatcgtcc ctacatcatc
    31921 ttgtttagtg attggtatgc tttcttgcgc atagattccg cctgcatcca tttttttgat
    31981 catttccatg atcgttacac cagtttcttt ctccccattc atgatggcat aatgaacagg
    32041 cgcacctccc cgatatttag gaagtaaaga agcatggaca ttgattgccc ctaattttgg
    32101 tacttgcaat aacttttcag gcaagaattg gccaaatgcc gcagtgacga tcacatcagg
    32161 caccaattca atgatttctt ccatttctgg cgaaccggag attttctctg gctgcagcac
    32221 acggataccg tgcttcagag ccgctttttt taccggtgtc ggcgtaatta ctcgtttccg
    32281 cccaactgga cggtcgggct gtgttaccac tgcctggatc tcgtaacctg attctatcag
    32341 cccttcaaga atcggcacag aaaaagcagg tgtgcccata aatactagct tagtcatcaa
    32401 gatgttcctc catatattct tcaagttctt cttccgggat ctgctgtatc attttctcaa
    32461 tgaacaagat accgtctaag tgatcgattt catgctggaa ggcacgggct aaatagccaa
    32521 aagccgtcac ttctatctct tctccgtctc gatcataata acgcacggtc acttcatctg
    32581 ctcgcttgac cgttccatag acatgcggaa tactgagaca accttctacg tcaaggcttt
    32641 caccttttgc ttcgatgatt tctgggttaa tcagttcaaa tttctcgcct tcatctactt
    32701 cgatcacagc aattctcttg ttttgtccta cttgaggagc agcgatccct attccgtcat
    32761 tcgcaatcat tgtctcatat aaattgtcta ataaagcgat tgtctcgtcc gtgattacat
    32821 cgattggctg agcagttctt tttaatttat cattagggtg gatcaatata ggatagcgca
    32881 taatttggcc ctttcttaaa taaagtttaa tggttcgttg tcaattgcca caaaaagacc
    32941 ttgtcgctgt tctttctggc ttccattcaa aatttcatcc aaaacatgag gaagattcgg
    33001 ttcatgttta tatttgatga ttagttgata ataatatcgg tttttcactc tcaaaatcat
    33061 gctgggcgtt ggccctaata gcaagctttg agggcttaac acttctttta gctgattggc
    33121 aatctgaaag attttctttg ccgctacttg ttcttcagga tggctggcgg ttattttcac
    33181 agtaaagtaa taaggaggat agcctccacg atgccgtaca tgcatttcct gctgataaaa
    33241 ctgctcataa ttttgttttt tagccaattc tatggcgtaa tgttgaggat tgaatgtttg
    33301 gatcacgact tcgcctgctt tttccgctcg ccctgctcgt cctgaaactt gggtaagcaa
    33361 ttggaatgta tgctcactag aacgaaaatc cggtaaattc agggaggtat cagcattcaa
    33421 caccccaact aatgtcactt ctggaaagtc caaaccttta gcaatcattt gtgtccctaa
    33481 taatatatct gcttcttttg caccgaattt ttgtaaaatc tgttcgtgtg ccccttttct
    33541 tcgagtggta tctacatcca tacgcaaaat cctagcttgc ggataaagtt ctcggagttc
    33601 ctcttctact ttttgagtac ctgttccata gtagcggatt ttattgccgc cacaattagg
    33661 acagcgattg ggaataggtt cttcatgtcc gcaataatgg cagcgcattg aacgtgtatc
    33721 catatgcagt gtaagagaga tatcgcaatt aggacatgga agaacaaatc cacagtccct
    33781 acacatcaca aaagacgaat atcctcgacg attgagcagt aggacagttt gttctttttt
    33841 gtctaatcga ttttgtattt tttcctgcaa attagcagaa aaagtagagg tccgatgatt
    33901 ctgaaactct tcacgcatat ctacgatctc aatagctgga agctgtgcag ctgctttggc
    33961 tcggtggttt aactgcaata actgataaac gcctttttga gctcgtgctc ttgattctaa
    34021 agagggcgtc gcgcttccta gaactattgg gcaatgatga tatttactgc gccaaattgc
    34081 tagatctctc gcatgataac gcggtgtctc atcttgtttg taacttgatt catgttcttc
    34141 atcgataatg atcagcccga tatttttcag cggggcaaaa atagcagatc gtgcgcctac
    34201 tactacttgc gcttcttccc gctcaatctt gcgccattca tcatattttt caccttggga
    34261 aagtccgcta tgtaagaccg caactgattc tccgaagcgt cctttgaatc gctcgaccat
    34321 ttgcggagtc aatgcgattt caggcactaa cataatagcc gttttatttt ctgacaaaac
    34381 atcagcgatt gcctgaagat atacttctgt tttcccgctg ccagtgattc cctccagcaa
    34441 aaagacctga tctttttgct gctgacctgc tgtgatgatt tgttcgacag catttttttg
    34501 ttctgcattc agttccaatg ccgtcgtttg gtcaaatact cggtctttat aagggtcgcg
    34561 ataacgttct gattctataa actccagcca gcccttttct tttccttgat tcaagacagc
    34621 agtactgatt cctttatttt tgaaataagc aattggttct tcttggctca gttcagataa
    34681 acacaaaaga agttcttttt gtttcttggc attttgccgt aattttgccc attcttcttc
    34741 gatttgcttt tcagttaaca aagaacggac caaacgaatc gtttttactt tatttcgtgt
    34801 atggacttca tatttgatat ctactaattg ctcttggcgc cagcgaatca attgagaaag
    34861 gctgccttct tcttctgctt ccttccagga aatcacttct cgctgatcaa acaatacctg
    34921 aacttctggt gtgtctgcca aaggatagat caatttatca tattctgctt tcatcacact
    34981 cggaagcatc gtttgtagac aagtgatttt gaatgcgtaa gtaatttttt tcatataatc
    35041 agctaatgaa agtaattctt cattgaccac cggagcaagg tctagcaaac gaataactgc
    35101 cttcaaagat ggattagctg attcttctga tttttggata gccataacaa atccttggac
    35161 atgacgattg ccattaccaa aagggacttc tactcgcatc ccgacttgca aagctgtttc
    35221 catttcagag ggaaccaaat aagtgaatgg ctgatcggtc tgcatagtag gtacgtccac
    35281 aatgacttca gctgttaatg tcatggttcg tttcctcctt tttttgtctt ttcttatcaa
    35341 gcgacaaaaa gttccttgcc tattttacta gagatcgatg gatttgtctt atcttctgcc
    35401 aaatcctaac aaaaaattaa cagcagataa gaaaaaaaag aactgtgtca aaaagttcag
    35461 acacagcctt ttctaccaga caataagtgg cgaatgtttg aaaaggaaac agctgggttt
    35521 gcttttcttt ttagatgttc gctctatttt tctttattac attttttgct cttcacggat
    35581 acgtgattcc aattcgtgtt gttcacgctc tttttgtgct tgacgttcct cttcttccat
    35641 cttcaaacgt tcacgtttta attcaggatg tggatcattg actacatttc ctgcatcgat
    35701 ttcttctaaa gcttgaccga cgctttttac tgaatcaaaa gaatctagag taggctgtgc
    35761 acttgcatcc aattcatgcg cgcgtttact tgctaaaatc actagagaat attttgaatt
    35821 tacacgatct aatagtgagt caattgaagg ttttaacatc ataagactac atctccttta
    35881 acattttaat atatttaccg attacgcgat ctactcgaaa atgttcactg gcaataatgt
    35941 ttttgattcg ttcaactgct agcggcactt catcatttac aacagcatag tcgtaaagag
    36001 ccatcatttc gatttcttct tttgcaactt tcattcgttt ttcgattact tcatctgcat
    36061 ctgttcctcg gcctacgatc cgtgatttta attccgctaa atctggcgga gtcaaaaaga
    36121 tgaatacacc atcgggcact ttttctttga cttgttttgc tccttggact tcaatctcca
    36181 agaaaacatc ttttccttca tccaatgtct tgttgacata tgacaaagga gttccataat
    36241 aattcccgac atattctgcg tattccagca tctctccagc ttcgatcatt gattcaaact
    36301 cttctttgct tcggaagaaa taatcaacgc cttcgacctc cccttcacgc attttacggg
    36361 tagtcattga gatcgaatac tgaaaatcat tatcctcact ctcaaaaatt gcttttcgta
    36421 ctgtgccttt tcctacaccg gatggaccag acaacacgat taataatcca cgctctgaca
    36481 tgacgacgtc ctttcaacta gtctttttgt acttatcgtt tattttgcac tttttttctg
    36541 caactttcaa ggttatcttt aattatagct agaaattggt aaaaaagcta ccctgtacca
    36601 agaggtcgta aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca taaacagctt
    36661 ctcatgtttt tcgtttggtt ggggttatta tcgcagatgc aagcttttga acgccgtgta
    36721 taagaggtcg tgaagaagcc gattagtttc gagtatgaag aaaaattttg tgaaaatagt
    36781 ttctcacatt tttgcataaa tttggcttaa taccgagaaa atggtttttg aacatcactt
    36841 attcaaaata aaaaaagatt gtgacacgaa ttttgtcaca acctttaaat gtattcctag
    36901 agcaaagaag ctaagcgaag aaatccaatt ctgtttattt attgtatttc tttgttcagc
    36961 atccttgcta aaagcccata ttggacaaag tattcactac acccatgatc tcatcttttc
    37021 gagaacgtgc tttttctgtc ggatcttcta cctcttctgt gtcaattcga acaataaatt
    37081 tccgattcat cgtcacgtaa gcaccgtcgt tgatcaaaat aaacagttcg ttctcattat
    37141 agtctgcaca ggcatctttc catacgtcaa agccgttttt ttcagaaggg atatcccgtt
    37201 taaccacagt ttttccactt aattcgtgga acgttacgtc ataatatttc attatctcta
    37261 cctctttcgt cattcaatat tttgtacttg ttctctgatt ttttctaaga tcgtcttaga
    37321 ctggacgact tgatttttaa tttcgattgc atttgatttg gaaccgatcg tgttgatttc
    37381 ccgattcatt tcttggatca ggaaatctaa ttcccgacct acaggacatt gtgcttcgat
    37441 aagttcatct agtttttgta catggatcgc cagacgatcc agttcctcgt gaatatctcc
    37501 gcgttccaac aagatggcta gctccgtcaa caaccgttgc tcatcgactt tcgctccaag
    37561 aaattcctcc agcttttttt gataccttat ttgaaattcc ttttcataga tttctacaaa
    37621 actatcgagt ttttttagta cttctttgaa ttcttcagta ttctttttca acactaaagc
    37681 taaagcttga ccttcttttt ctcgactcgc ctcaatagaa tcaagtgcgc ttttcaatgt
    37741 atctagagct aactgtgcca attcttccat gctctcttcc ggtttttctt ctaccgttac
    37801 gaagttttcg tccagcacga agcgttccgc catccgacta attgacactt gattttgact
    37861 accgtatcgt tgttgaattc cgtctgtcaa ttgagtgata agtgaatcaa tcaattccca
    37921 gttgatgacg atctgttttt cgtttttgcc aatataagct agattcacaa atacttcgat
    37981 tcgaccgcgg cttaactgct gtttaataag ctgacgaaaa tcgttttcaa caaagttcag
    38041 gattttagga cttcgtattt gaacatctag aaaacgctgg ttgacacttt ttatttcaat
    38101 atctaactga tacgcttttg tttcgcggat ggctttgcca aaaccagtca tacttttcat
    38161 tcgacagggt ccttcctcat tacatatttt ctattgcttt ttgcagttgt tcaaactctt
    38221 cgttcgtcaa tgtcaggcct ttccccattt tttcatggtc tggcgcccaa tctcgaagat
    38281 cgaattttgg cgggcgacca ttccagctga ctaggttcag ttctttacgc caccccttgt
    38341 tgttttctga caatatagcg atttcttcta cgatttcata tgaaaattct tgtgccatgg
    38401 ttgttcctcc ttgagataat ataaatatag gatcagtaat gtgtcaactg gttgcttaag
    38461 caattcatgc tgcaaacgat ccttgcgttt tccttgtagc agataatcaa aataaacagt
    38521 tttcgtgcgc tcattttgta ttttttgctg gtattttcga taccttcgcc attcttcagt
    38581 acttaattga ccaatttgtg ccaataaatc atccggcata ctttttatat cttgttggca
    38641 gatcatttga atcatcatgt ctacttgata gatttcattg ggcagtaaaa aatgtttttt
    38701 tgctaaaagt tctagcatcg ccaatccgca tgtctctggt acgaccctgt tcttatataa
    38761 attacgcagt ttttgccaaa attttatgct tttgaaaaaa gataattcta actgaatttc
    38821 ttttgttaag taagacaaaa atcctcgcca gtatgttctt gcaggtttaa cagaatgaaa
    38881 tgtataccag ttcccatagt aatagcctaa tcgttttttc atttccagat agcctaattg
    38941 taaatttaat tggttccttt ggctatcaaa aagcagaaag ctgcctagtg tccacaatgt
    39001 ttgacatttc caatggataa aaatgtctgg catacgaatt tttttcgctg ggcctggccc
    39061 ttgcacatct acgacaaatg cctctgttgc tcctttgtta atcgcaatat caataggtat
    39121 tttgttgcga tacccaccgt ctgcatattt attttttccg atctttcgat aagccatagc
    39181 gggataaaat gaagcagagg cgagtatcca atctggtatt tcttctgttt ttgtctgttg
    39241 gatatcagtc actacttccg ctagttctgg cagtttagta gacaccgtat ataaacgtat
    39301 tttgggatta tgtttgagta aggacaaatc caaattgtct ttgaccatct tttccaatgg
    39361 agcagaagaa accccgcctt caattagtgc tgttttcgtc atttggcgtc tttctcgata
    39421 gaagcgttca cgaaggtctt caactgcagc catttctggt aacgcaagca cttgtcttgt
    39481 cgacagcttt ttccataaat tcacagcttt tttcatatct ccttgtaaaa tcaatgcgcc
    39541 gttcaacgca cctaccgagg tacctgtgat aatctcaaag ttgatatcat gttccttcag
    39601 cgcctgccac acaccaatct gataagcacc gtgcgctcct cctccaccta aaacaagtgc
    39661 tgtatgatag accagctttt tatttaattg tgtggttcct tgatagccgt ttttatgaaa
    39721 aatacgcaac cattcttctg atagaggaga ttgaaataaa aaacaacagt tttctttaat
    39781 aaaaaaacga gcgcaagctt ccatataccg aaaaaatttt ttccattcaa aagtttcacc
    39841 ttcaatcaac agattattaa aaataacatc tcctctactt ttagcaatag taaaatagac
    39901 ggtatatttt ttcgatactg ctttaaaagc acattgcttt tttgcagaac gccaaaaagc
    39961 gtctctactt tcttgatgac tttgaaaaaa tggaaggggt tgttttgctt gctggatagg
    40021 cgaatacagc gacattttct gtgaaaagta aacttttttt atctccatcg cgctctcctt
    40081 tttcttcaag tataccagta cgtcataaaa aggtcatgag tctcgtattc gactttgtag
    40141 attccataag aaaacaattc ataaaacctc ctttaaataa aaaaatacaa aaatcacaaa
    40201 aattaattga aaatgagagt gttttcaatg aaaacgtgat tttgtaatgg aattttaaaa
    40261 taaaagaaac aagctttttt aatgcaaatg ttgtaaaata aaagagatta agaggaaata
    40321 agaggaggaa catgatgact gagtcagttt atgtacatat tgataccaca agtaatgctg
    40381 ttttaacaaa agggctgact gctactgact ttgcaaacag tatcgtgcat tttcctcaaa
    40441 acttgctctt gcttgatcca tctgcttctg ctggagaata tgaatcccat acagggctga
    40501 aagtaatccg tggtacagaa aatattcagc gtttcttttc ctcttctcgt aacaggcgtg
    40561 gattcgatga attgaagtgg atcgacttta ctgatttaac gatgctgaaa gaattgacac
    40621 ctttagaaat ttcagaatta ttatattttg gtcatatgaa aacacatctt cattcgccgt
    40681 ttttttataa actacagaat aattttgtat acttcgatct taatgatcag ctgaatcgga
    40741 tttattatcg ctatttagat gaattttata ggatttttgc tagtaaatta agttcgatct
    40801 tgtcagataa gatcaatgta aaaaaatctt ttttcaaaaa agaaacacct gttgaaaaaa
    40861 tcagtgtgga attattgaaa gaaatgcgta atttgatgca ggaagggatc attttttctt
    40921 ttgatcaagt tggtttgatc gatggtaaat atcgtatccc aatctatgtg attgaagatt
    40981 atatttggaa attaaaaggc acccggtatc gagaagagga aatcatcgct actttaatct
    41041 actctgtcac cgatcgacac tggcaattgg tagaagatgc cgatctttct tatctgccat
    41101 tgaagtagat ctatttctta tcaaaaaata aaaaggaaac aagaaactag gacatgattc
    41161 tgtctcaagt ttcttgcttc ttttttattt acagctcctg tcgtttatct ggcacaaaaa
    41221 tcgaaggagt cgtttgttgg atccctaata aaacgatgat cgttacaata gctgtactca
    41281 acccgctggc accattcatt acgaaagaaa agagccaagg attcatcccc catagtgcat
    41341 acgctcccca gaaaaccact cctgcaataa aatgccaaaa atatctggaa agtgcgccaa
    41401 tcaatgcacc aaacacgatg ctttttctaa tttgtttcgt attatcgtct acatagcctt
    41461 tttggacatt tgaagccatg agccctgctg cgcctgcaaa agtataggca atcgggtact
    41521 caatcaacac ttgaacgaca cttaaataat aaacttgtcc caacggaaaa tgtaggatgc
    41581 cccaaatgaa acctgccagc atccctgcct ttgtccctct tcttaacgca aaaagagtca
    41641 atggaatctg ccctaatgaa atagaaaaac tgctgccgat ctggatcgga atcaacgaca
    41701 acaccatcgc taacgctgca acaatcgttc cttctaccca aactctattt tttcccataa
    41761 aaaaacttcc tcctttgaat aaaaaagtca caaaggagga agcagctttc gaaaatagtc
    41821 aaacagctgt ttattcacaa ttcctacgct cgcataaccg atacaggtac gaagggttta
    41881 gaaatagatt caatctcagc ccaattggac tcccctttgt gagtttattt attatttatt
    41941 ttttgtttca aacaatggac taactggttt gttttcatgg atacgtttga ttgcatctcc
    42001 cattagtccg ccaacactta cttcatcgat tttgtcgatt ttacgatctt ctggaagata
    42061 gatcgagtct gtaacaacta gacgctcgat agctgaatct tctattcttt gtaaagcagg
    42121 gccggataat actggatgtg tacatgaagc atacacacta gttgcaccag cttctttcaa
    42181 agcattggca gccaatgtga tcgtacctgc tgtatcgatc atatcatcga tcagtacaca
    42241 agttttgcct ttgacttgtc caatgatatt cattacttct gcaacatttg cttttggacg
    42301 gcgtttgtct atgatcgcaa tcggagattt caaaaattcc gctaatttac gtgcccgtgt
    42361 gacaccacca tggtctggtg aaacaacgac aacatcatcg cctttgattc ctttttctaa
    42421 gaaataattg gcaataagtg gcgcacccat caaatgatcg actggaatat caaagaaacc
    42481 ttggatttgg actgcatgaa ggtccaaagt cagcattctt gttgcaccag ctttttgaat
    42541 catgtttgct actaatttcg ctgtgattgg ttcccgtgca cgtgctttac ggtcttgacg
    42601 cgcatagcca taataaggca tgactacgtt gattgttttt gcacttgctc gtttcagtgc
    42661 gtcaatcatg atcagcaact ccatcaagtt atcattgact gggctgctcg ttgattgaat
    42721 aacatagaca tgcgatccac gaatactttc ttcaatgttt acttgaattt ctccatcact
    42781 aaattgagta acagatgatt ttcctaactc gacgccgact gctgctgcaa ttttctctgc
    42841 taatgggcga ttggaattta acgcaaaaat ttttaatctt gggtcaaagt aatgttttga
    42901 catggggacc tccactttct ttttcacaac tctagaattc tacctaataa atagtagtca
    42961 tattttttaa ataaatcaag tgattttgca aaagtcttag tttagataag ggagtttttt
    43021 tgcatatcct tctttattga cttgtcttgc tctcgcaatt gccagcgcat attctggaat
    43081 attgtctgta attgttgacc cggcagcaat cgaactgttt ttagctacct cgacaggtcc
    43141 gatgatattc gtgctagaac caataaagct gtggtcgccg acagtcgtat gatgtttgtt
    43201 ctttccatca tagttgacga agacaacacc acatccgaca ttgatttctt ctcccagcgt
    43261 agcatcacca acataagtca agtgaccgac tttagttcct ttgccgattt gagcattttt
    43321 cacttccaca aagtttccga tatggacgtt ttcgccaatt tcagcttttg gtcgtaaatg
    43381 tgcataaggt cccacatctg catgtttctt gacatggctg ctttcaatga ctgagttttc
    43441 aatgacgacg tgatcctcaa tcctactgtc tacgattttt gaatgtgacc cgatgacaca
    43501 atcagaacca atgactgtat ttccttggat ttgtacacct gcttcgatca atgtgtctgg
    43561 accgatttct acgcctgcat cgatgtatgt cgttgctgaa tcgacaaagc ttacgccatt
    43621 gaccatatgc atctggttaa ttcgctttct catgatctca tttgctttag ctaacgcgat
    43681 ccgatcattg actcccattg attcttcaaa atcatccgtt tgataagcag caactgtatg
    43741 gccttcttct tttaagattt cgatgatatc tgttagatag tattcacctt gagcattgtt
    43801 tgttccaact ttgcttaacg catcgaacaa agcttcgttg tcaaaacagt aagttcctgt
    43861 attgatttct tgtacaagag cttcttctgg tgttgcatct ttttgttcca cgattttttc
    43921 tacgatccca atatggtcac ggatgattcg tccatatcct gttgggtttt ctgcttgtgc
    43981 cgtcaagatc gttgcacttg cattttttcc ttggtgatat tcaaaaagat tgttcagcgt
    44041 ttcagtagtc aataatggtg tatcgccact gataactaac gttgttcctt tttttccttc
    44101 caagaaagaa gcagcttgca aaacagcatg tcctgttccc aattgttctg cttgtaacgc
    44161 atatttactg cgttctccta gttgtgcttt aacttgttct gctccgtgtc caacgatcgt
    44221 aatcacttca tctggtttcg tttcactgac ccgattaatg atatgttcta ccataggttt
    44281 accagaaacg ggatgtaaaa ctttatataa ttttgacttc atgcgggtac ctttccctgc
    44341 cgccaaaata attgcataac gtgcgtccaa ctgcgtcact cctaaatata gtttgctgat
    44401 ttcagtttat cccagtatac ccattttttc aacaaaacaa gtgattttct tttatcccag
    44461 cgttttctgg ataaaaaaat agatagacca taacgggcct atctatttgg taaccggtgc
    44521 tctcctgcca actcctcggt cacaagtcac actactcata aaacatgaaa agctgttttt
    44581 tgaaatcgtt tcttgtgact tagagttaaa cggtaggctt acaacctctt cattaaacgt
    44641 ttttcaatca gctgaccttc ggtattagct caataaacgg caaaatatga ggagcaattt
    44701 ttccgtttat tgagctaata ctcaggacag gacgctgatt tcacaacctc tagataaacg
    44761 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gaaaaaatgt ggaaagccat
    44821 tttcacaaaa tttttcttac tactcgaaac taagcggctt tttcacaacc tcttattctg
    44881 aaaaataatt tcctggcaca accgtaatat ttttcgtttg agtatctaca tctttgacat
    44941 aaagcagtga cgtataatca tcgatggcgc gatgaccgtt gaattttgat tcggcaaata
    45001 cagtgatgcc aacaagttct gattcgaatt cttcaatcaa gctcttcatt ccgttgactg
    45061 ttccgccgcc tttcatgaaa tcatccacta caaggacacg tgaaccacgt ttcaaacttc
    45121 tcttagacag ttccatcttt tcaattcttt cagaagatcc agacacatag ttgacactta
    45181 ctgttgatcc ttctgttatt tttgagtccc ggcgtacaat aacgaatggc gcattcagat
    45241 aataggacac agcttgggca ataggtacgc cttttgtggc tacagtcatt acagcatcga
    45301 ttttttcacc aaggtattta gaagcaatga ttcttccaac ttgacgcagc agttcaggtt
    45361 ctcctaacaa atcagagaga taaacatatc ctcctggaag cagacggtct tgttctgata
    45421 gacgttctgc tagagattca atatattttt tcgcctcttc atatgaaatt tcagggatga
    45481 acaatacacc acctgcagca cccgggattg tttccaaggt tccataccct cgttctttaa
    45541 atgttttctt gatgattccc aaatcttcac tgatagaaga tttagcagat tcataacgtt
    45601 cggcaaagct tgttaaggaa atcaattcat gcgggtgatt caataaatac tgtgtcatgt
    45661 caactagacg ttcactgcga cgtactttca cctattccaa ctccttttaa gaaattttat
    45721 cgttttacat tatataagtt tttcttcaaa aattcgagca ttttatgaaa aaataagaaa
    45781 atagttcggt atttattaaa ataaaaagaa gcctataaaa aatttttcgt ttttataagg
    45841 cttcttttct ttataattta gttatttttt cttctgaagg caaccaatat tcgtttgatg
    45901 atatttacaa tcaggaacaa agcaataaag actaatgtga ttgttgctcc tggaggtgta
    45961 tctagataaa acgagctagt tagtcctgac agcatcccta gaaatcctac acaaacactg
    46021 atagcaatca cgacattgaa gcttttgcct aatcgcatac cgattgctgc gggaagaacc
    46081 atgattgcgg atatcaaaag tgcaccggca atcgggatca tcacagcaat agccacacca
    46141 gtaatcacat tgaacatcat cgacatcaaa tgaacgggta gcccatccac gtgggcggta
    46201 tcttcatcaa aagtcagaac atacatcggc cgtttgaata aaaagaacaa tataccgatg
    46261 gcaacgaata agattcctaa aaagatgact tgctcccatg taatggtcac gatcgaacca
    46321 aacagatagg attggatact tgttgctgaa ttccctccgc tcaaattcat caatactaac
    46381 gctagcgcca aaccaccagc cattaaaatg gcaatggaga tttctgaata ggttcggtag
    46441 atcgttcgca gatactccaa tatcacagct gctaatacaa cgactagcat ggtcgtaagt
    46501 gtaggattaa ggttcaaaaa gaatcctaac gctacccctg ctaaagagac atgagaaagc
    46561 gtatcagcca tcagcgattg tcttctgatc actaaaaaca cacctagcat cggggcgatt
    46621 ccggcaatga agatagcggc aagaaacgct cttctcatga attcatatga aagcaacgcc
    46681 attgagaatc ctcctttctc accagtcgga tctgtctgtc cgcatactgt ttgatatctt
    46741 catgatcatg ggtgatcatt agaactgatt tcccatggac atgcgcacta tgtcggagaa
    46801 gacgataaaa ttcatttctg gattcttcat ccatacctgt tgttggttca tcaagaacaa
    46861 ataagtcagg gtcagtagca aaaatacgcg ctaaactgat tcgctgcttt tgtccgccag
    46921 acaattcacc tattcgccga tttcgcatat cccacatccc tacagcttct aaagcacgct
    46981 gtacatgttg atgatctttt tcagagagac gcttgaacca gcggcctctt ggatatcttc
    47041 ctgaacggac taattcgatc accgtactag gaaaacctgc attgaaagat gcaacttgtt
    47101 gaggaatata accgatactt aatttttttc cttcttgatt tttctcagca atctttatca
    47161 ttccttttga aggtttcagt aatcctaacg atgctttcac caaggttgac ttggctgctc
    47221 cattttctcc agttaaaatg acaaattcac ccgcatctac atgataagag acatcttcta
    47281 gtacaggttc atcatcatag taaaaggtca aatcagatat ttcgatataa cgcaccttac
    47341 aacctccatt ctaaaactta attgatactt tcttttaaag ctttcagatt tttttccatg
    47401 acagaaatat aattttcgcc tgctttgatt tgttcattag tcaagctttc taaaggattc
    47461 aacacttcta gcttcactcc tgtttcattc gacaatgtct cagctacctt cgaagaggca
    47521 ttttcttcaa aataaatcac tttgatgttg tttttcttca caaattcttt tagctcagct
    47581 aagcgacttg gtgtgggttc ctgatctggt gaaacgcccg aaatcgctac ttgttttaag
    47641 tcgtattgat tcgctaaata agcaaaagca gcatgctgag tgacaaatgt gcggtttgtt
    47701 gcatctttta gctcatcgga gtatttttga tccagtgctt caagcttttt gatataagca
    47761 tcggcattct tcgtaaaagt ttccttttta tctggatatt tttcgcctaa ttcttcagca
    47821 atcgttctga cttcttttat agctaatacc ggatcgagcc aaacatgtgg atcgtattca
    47881 tgtgaatgac catgcccttc ttctgattct tcatgttcgt ctgcttcttg cgattctaaa
    47941 cggtcgattc ctttagctgc ttcgatcatc aaggtctgtt tgctatccac tgaatccttt
    48001 aacgaatcca caaaaaattc catgtctgaa ctattataca cgaaaacatc tgcatcggaa
    48061 atttctgctc tttcttttgc acttggttcg aaatcatgcg gctccgttcc agcagggatc
    48121 aaaagtttca cgtttccttc atcccctacg atctcttttg taaaatcata catcggataa
    48181 aaagtcgtaa cgatcgtcaa atcctctttt ttgtctgctt ccttgttcgt atttccacat
    48241 gctgcaaaca gtaaagcacc tatcattacc gtagctgtca aaagatattt tttcatttat
    48301 atgctccttt caatgaacaa atcggaattt tacgatttat taacgtgaac taatgtatca
    48361 aaataaaaaa acacagtcaa tagaaatcca tcaatttctg atttaagcat gtatattctt
    48421 gattaaatcg taaaatggat gagttgctgc tcatatctag ccatttcact acaataaaaa
    48481 actgaagaat accattttag gattcctcag tttttcatca cctattttac ttcttatatt
    48541 ttattgcagg gttcgtacta aataaacttc ctcacaaaaa ccttttaacc cattatatac
    48601 tctctgcgct cttgaataat gttgacacaa ggcaaaaacg gttggtccgc ttccactcat
    48661 caatgcagca tctgctccgt acttgatcat acgctctttg atttgatgga tgactggatg
    48721 ccgctttccc gttatatctt ctaaactgtt tcccattttt ttgatcatct gctgataatc
    48781 ttgctctcgg atggcttcag caagtccgtg gatgtcttga tgttggatgg cttgcgtatc
    48841 tacttctcta aacactgtac gtgtagagac actcattctt ggtttgacca acacaaccca
    48901 gcactgtggc atagaaggta atacttggat ttcttcccct ttgccaccga caaatgccgt
    48961 acttccgtag acacagtaag gaacatctgt accgacttcc aaaccgattt ctgccagttc
    49021 ttctaacgaa cagcccagat tccataattg gttgatccct cttagagcag ctgcacagtc
    49081 tgtacttcct ccgcctaatc cagctgctac tggaatattc ttcttaacaa agatcttgac
    49141 accggttttg atattgtatt tattttttag caataaagca gcttgataaa cattgttccg
    49201 ttcatctacc ggtaaaaatg ctttatttgt ttctacaatg attttgtctt ctgttatttc
    49261 ttcaaaaaat agatgatctg ccaagtctac gctcgacatc accatttcca actcatgata
    49321 cccatcttgc cgtctatata atacatccag tcctaaattt atcttggctg gcgctttttc
    49381 aatcaattcc atcctctcac ccattcgaaa agtctaagtc gcaagtattc tatcataggg
    49441 aaaaataaaa gtatagctta tgtctgccta gtggttgatt ttgtcatcgt ttcaacagct
    49501 ttcacagaat tttctcttca taatccaaac aagttctagt gattcttata attctgtgag
    49561 cacttcttct gccaaactcg gaacatttcc tttttctttt cctatcagac tgagtagctg
    49621 catggtagca aatccgaaat tacttccttt cctataagca aaataacgtc cttcccaatg
    49681 atcgacatat tttaatttct tttcataagc agactggaag gaatagaaaa aattaccata
    49741 attatatacg atatgcatga ctttttcttg aaagaaagaa aaatctgttt ctccaacatt
    49801 agctaatgga gctaagccta gattggcttc cgagtagccc attttctcgt atacaataaa
    49861 cagattggct aacagatagt cagctaattc ctcagattct ttaggtaaga cccgcaacaa
    49921 atcatatccc gcctgcttct tcgtcatcgg ctgagcggtg atgaagccaa cgactttttg
    49981 atctttacgg acaataccga caccgctaga taatacatat gatttatcaa atcgtcccac
    50041 agagaagtat ttttctcgtg caccttgaag ccatttttgt gaaacttcat ttacagcttg
    50101 atgtaattct tccggcagtt gatcgtacca agtaaaatgg tatccttctt tcatcaaacg
    50161 ttgatattca agttgctgac tcagccgaga caagtcttct gttgctagat caacaatccc
    50221 tgcttcacct actttcgtga agtgaaaacc caattcatga agcatcacta cgtagctttc
    50281 tgatatctta taaaacgcaa gctgatagcc taaacaatct gcttgtttca taaactgatt
    50341 cgttgctgcc cgcatcattt taggattgcc aactggatct cctaaaacaa agcatttgtt
    50401 tcctttgatc tgataaccaa aaacgacttg atcttggtcg tcttcttggt aataaaaata
    50461 actgtaacct gacaagcgaa gctgatggct tgtagctgtg cctccgtatg tttccaataa
    50521 acggtcaaaa cggtcttttt cgtactcact gccaagcttc gtagtatctt cagctaaata
    50581 ttgataaagc gccactaaag ctagcaatga gatgcccaaa ccaataagcc ctgagaacca
    50641 cacatcatct gaaggaaaca aaataaaatg atttcctgtt attcgaccga ctaaaaagcg
    50701 tccgctgtga tagcctgcaa ttgcgtaaac gataaacaaa aagccgaaca agctagcatc
    50761 aaagattata gctccccaag aataaacgaa ttttgttcga taaaattctt ttctggataa
    50821 ccacacagct aacagaatca agacatatac caatatcaac tgccaagata acgtacgtgt
    50881 gattgtattt aaaataccaa aagatagtaa agcaatcgta ggcagaaatg cctttttgac
    50941 ttttactgaa agtgctctag caaggccgag taataaaaag ccaaccaata gattcactgt
    51001 ctgatctaaa aaattgaatg agaacggcaa taatacttga aatagccgac tgattgcaga
    51061 cagattagtg attgttgata gaagtaccat catgatcccc gcaaaataga cagcacttac
    51121 gagcacgata tgcgcaacct tttggaaaaa cagtcgcgga atgttatcta aaaatcgatt
    51181 gattttgact cctgtatgtg tgatgaacaa tagaagtccc gtcataaaag gtagaacata
    51241 ataaaacaac cgataatata atagccaaac tactgctaca tcttgccgaa cagacaattg
    51301 actcattcct aagatcatca aaacgtcaaa agtccccatt ccacctggga ccatcgtcag
    51361 cattcctatc aatgtagcaa tcatgaacat aggatagatc gaaagcatcg aaatatctat
    51421 tctcatcaac ttgccgatga tcaaaaatac cgcaagggct cccgtccatt gtccaaagga
    51481 tgccagtagc agaccaagca agccttttgg ataaaactcg aagaacaatg tctttctctt
    51541 tagataagca aaaaagaaaa tgactggtgc taaaaaacta ccgccgaaaa gccagatcca
    51601 atagcttcga aaaatacttt ctgactgaat aaaaaagaca tcaataaatg taagaaacga
    51661 ccatacagac aaaccagtca gcataaatag tgcgactttt gatacagtgg ctaaaaccat
    51721 ttttctattt gtctgctttc cataaaaact agcccgcaga cttgctccta ccacaccacc
    51781 aaaaccggcg agattgttga tcgtgtttgt tacccacgca gcaagaagaa actcttttct
    51841 ttccattttt ggttttcctt gtttttctaa gactctgatc gtcacccaat catacaacaa
    51901 catcggagtg acacccagca gtccagccag aatcatgagc aggatcgtca tgcggctttg
    51961 ttgtcccatc ctttgccaaa tatcttgcca actcatgcca ttagcaatat ttgcgacttg
    52021 atttgccaca aagactaaca cggagccgaa aaaaatcagt tttaaaatca gactatgttc
    52081 ctttatccat tgcagcatca agtatcgttt atttttcaca ttttcccatt cctaacttgt
    52141 atacttttgt gtcatacccc aatgttatct tatttatttt aatttttcca ctttagacct
    52201 gttctttgct tgcgatgata gaaaaagaaa gatatcctaa tgctaaagga gaggataaca
    52261 tgaaagtagg atttatcggc acagggaata tggcacaagc tattattgat ggtttattaa
    52321 aaaaaggaac agtctcgaaa gaagaggtgt tcgtttccag tggacatttt gaaaatgcac
    52381 aaaaatttgc tgctgaaact ggcgtccatg catgcaaaag taatcaggaa gttgcatcac
    52441 aatcagatat cgttctttta gccgtgaaac caaaaatcat tgaaaaagta ttggaagaac
    52501 taagagaata tagccagaaa gtcttattca tttctattgc ttcaggaaaa tcattaatag
    52561 atttagaaac agcgcttgaa gatcctcagg cctccatcgt acgtgtgatg ccgaatgtca
    52621 atgtcagcgt aggagcaggc gtttctgcga tttgcaaaaa tgaagctgcc acggaggaac
    52681 agcttcagca agctacgatg atttttgaag caatcggcag cgtctatcct ttagcagaat
    52741 cagatttcag tacattcatt ggccttgctg gcagctcacc cgcattcgtt tacatgctga
    52801 tcgatgcgat gggacggact ggtgtactga atggtttgtc caaacagaca gccactgaga
    52861 ttgctgcaaa agcaattatg ggttcttgtc aaaaattcct ttcaagtgat aaaaatccat
    52921 gggaacttgt agaccaagtt tcttctcctg gcggtacaac tgttgcaggt gtagttgcct
    52981 tagaagaagc aggattcatc ccagcaatca tcaaaggaat caatacgacg atcgagaaag
    53041 atcttgagat gttgaataaa aaataatgat agcaatgttt tttcgtgcct tacaaaaaaa
    53101 gaagagctgt ggcttttgcc gcggctcttc ttttgtattt tttattattt agcataatca
    53161 gttgcacgag tttcccgaat aacgattact ttgatgtgtc caggataatc cagttcttct
    53221 tcgattcgtt tacgaatatc acgtactaaa cgaacagcgt ctaaatccga gatttcttct
    53281 ggcttgacca ttacccgaac ttcgcgtcca gcttgaactg cgtaacttga ttctacaccg
    53341 gcgaagctgt tcgaaatatt ttccagactt cttaaacgac ggatgtagtt ttctaatgat
    53401 tcacttcgcg caccaggtct tgctgctgag agcgcatctg ctgcagctac aaggacagag
    53461 ataacagaag tagcttccac atctccatga tgagaagcga tcgcgttgat tactactggg
    53521 ttttctttgt acttggcagc taattccgca ccgatctcaa cgtgagatcc ttcaatctca
    53581 tggtcaagtg ctttcccaat atcatggagc aacccggcac gttttgctaa ttggatatct
    53641 tcgccaagct ctgctgctaa gataccagct aattttgcaa cctcgaccga atgcttcaag
    53701 acgttttgtc cataactagt tctgaatcgc agacgtccga tgatcttgat tagatctgga
    53761 tgaagtgtat gagcaccgac ttcaaacgct gcctcttccc cgtattcgcg aatacgttca
    53821 tccatttctt tacgagattt ctcgaccatt tcttcgatac gcgctggatg gattcgtcca
    53881 tcttgtatca gtttttccaa ggtcatccgt gcgatttctc ttcggattgg atcgaatccg
    53941 gaaagaacaa ctgcttccgg tgtatcatcg atgattaaat cgataccagt cagcgtctca
    54001 agcgttcgaa tattacgacc ttctcgtcca atgatacgac ctttcatttc atcattcgga
    54061 agggtaacga ctgaaacagt cgtttctgaa acttgatctg ctgcgcagcg ttgaatcgct
    54121 aatgataata agtttttcgc tttgcgatct gcttcttctt tggcacgctg ttcagattct
    54181 tttaccatta gagttaactc atgattcagc tcttcttcag tcgatttcat gatgacatct
    54241 cgtgcgtcct cttttgataa accagcaatt ttttctagtt ctttttgttg atcttcaatc
    54301 attttttcaa cgtctttttc tcgctcttca attaattgct gttttgaact aagtgcttct
    54361 tctttacttt caagtgagtt ctcgcgtttt tctaacgagt catctttacg attcagcgtt
    54421 tgttcgcgtt gaatcaaacg attctcttga gattttaatt ctaacttact ttctctcagc
    54481 tcactttcaa cttcagaacg gtatttctga ttttcttcct tagcttctaa caatgcttct
    54541 ttttttagag tttctgcttc tttttttgca ctatcgatga ttccagcagc tgatgattgt
    54601 gcaccagcta tttctttctc gtgacgtgac tttgcgacca taaaccctaa accaagaccg
    54661 acaattaaac cgatgatagc gaggagaatg ttgaatacca taaaatccac ctccatacta
    54721 tctttttcat ttttatcatc tatacagctt ctatgataaa ttattctaaa ctcgtcaata
    54781 tgcatcttcg catatatgtg tacaaaaaac atgcacaact ttattctaat gtttgtaccc
    54841 cgtagtgtca actttaaata aacaaagaaa cggctttcta cttattcatt aaacgatggt
    54901 ttttaaaata aatgacacta gtttcatata ggtaaacctt taaattgaga aacttttcta
    54961 ttaaattatt ctttgtagat gaacagatat ttttatttta tgtacccact cgtataatta
    55021 aataactcac gatttcttta ttcaataaaa aaacggcagg tcaaggagag tacctactct
    55081 tcagaccagc cgtttttgtt tatcataatt tttattcttc tactaaaggc aattcttctt
    55141 gtcctttttc atcttctggg acagcgactt cttcaccaat accataagct gctctaacta
    55201 gagcagaaac ttctgccatc atttcaggat gattagccat atagatttta gcgttttccc
    55261 gtccttgacc aatccgatct tctttataag aataccaagc accgctttta tcaacaatgt
    55321 ctttttctac tgccatgtct agaagttctc cttcttgtga gatccctaaa ccatacatga
    55381 catctacttc agcgattttg aaaggaggtg ctactttgtt ttttacgact ttgatctttg
    55441 tacggttacc aacaatatct gtaccttgtt tcaattgttc tgcacgacgt acttccaaac
    55501 ggatcgttgc gtagaatttc aatgcgcgtc ctccaggagt gatttctgga ttcccaaaca
    55561 tcacgcctac tttttcacgg atttggttga tgaaaatagc gattgttttt gttttgttga
    55621 tcgaaccaga gagtttacgc aatgcttgag acatcaaacg tgcttgtaac ccgacatgtg
    55681 agtcacccat ttcgccgtcg atttctgctc gtggaactaa agcagcaact gaatcgacta
    55741 ctacgatatc tacagcccca cttgatacta aagcatcagc gatctctaga ccttgttctc
    55801 ctgtgtcagg ctgtgaaaga agtagttcat cgatattcac acctaatttt tgtgcatatt
    55861 gcggatctaa cgcatgctca gcatcaatga aagcggccgt tccgccattt ttttgtactt
    55921 ctgcaatagc gtgtagtgca actgttgttt tacctgaact ttcaggtcca tatacttcga
    55981 tgatacgtcc acgggggtaa ccgccgacac ctaaagcgac atctaacgca agagagccac
    56041 ttggaattgt agagatttgt tggtcgattt tttcgcccaa tttcataata gagcctttac
    56101 catagctctt ttcaattttt ttcagtgcag catctaaggc tgctttacga tcatctgcca
    56161 atacgataat cctccttata tttacaaatc agagcaacat ttcattatcc ttatcatatc
    56221 ttttttagtg aaaaaaagca agaaaaaacc gaacaaatat tcgcatttat cattttctta
    56281 aaagctgttt tctcaaaaga tcaaatcctt gcataaccgc attatatctg atagcagcac
    56341 gatctctggc aaagtgatat ttttccgaaa ccacgccgtc tttagatgaa atagcgatcc
    56401 atactgttcc tgcagattga ccttctaacg tgtccggtcc agccactccg gtgaaagcta
    56461 cactgtaatc tgttcttgct atctcacgtg cttgaatggc catctgctcc acacattctt
    56521 tgctgactgt tccatattct gctaatagct ccggatcaat ctccagaaaa ccagcttttg
    56581 tttggagcga gtaggtaacg aatccgcctg gaaatacttc agatacacca gcaatgtcgc
    56641 ctaatgcggc ttggaaggcg ccggctgtca aactttccgc tgctgttaca gtctgcttgt
    56701 tttctttcag tagttccact acgacttttg ctagcgaatt atcatcgccg tatccataaa
    56761 aatattcccc tactcgttct tggatttttt cttctaatgc taaaagagct tgattccctg
    56821 cctgaacatc atttgttttc actgtcagtc gtaatgtcac ttcatttggt ttggcatatg
    56881 gtgcgatcgt tggattgatc tgtgtctcaa tcagatcttt tagctcagtg accagtcgcg
    56941 attcaccaat cccataaaag cgcaaaactt tagaaattag tttttcttca gaaggaaaac
    57001 gttcctctag taaaggacgt acttgttcca caaacattgg tttcaactca ttaggcggac
    57061 cgggaagaag gatatacgca tgtgtatctg tttgataaaa agtccctaaa gcaagccctg
    57121 tacgatttgg tagaggaacc ccgccttcga taatctggga ctgttgcaga ttgtttttgg
    57181 tcatttttcg atgggttgtt tcaaaatatg ccaataattt tttgtatcct tccgtatttt
    57241 gtatgagaga cttaccgagg tgagccgcag ttgcttcttt tgtcaggtca tcttctgtcg
    57301 gtcctaatcc gccacataag agtatgagtt cacttcttgt ttcagctaga gcaatcaact
    57361 cttctaaacg ctgctgatta tctcctacaa ctgtttgata ataaacttcg atacctagat
    57421 cagctagctg ttctgacaag aaagtggcat tcgtattcac gacttgtcct agtaaaagtt
    57481 ctgttccgac agctattatt tctgctttca ttacttcccg ctcccttata tagtatacgc
    57541 tgtattttta tattttttta tttaaaaaga gggcaaggag ctgtgacaaa aatcttgtca
    57601 cagctccttg ttccaaataa acagtgttct cctgccaaaa cctcggtcat aagtcacaat
    57661 atacataaaa catgaaaagc tgttttttga aattatccct tgtgactcag agttagacgg
    57721 caggctcaca acctctccac taaacgatac ttacattgat cctttgaaca caccgctgtt
    57781 tttgatgaag taatccacac ctgaatagat agtaaagatc agacaagcat aaagcatgat
    57841 ttgatctact ggaataccga tcaggctgaa tgggatatta ttgataaaca gcaagataat
    57901 agcaaccatt tgtgtagccg tcttgacttt tcccggccaa gctgcagcca tgacttctcc
    57961 atgttcgaca agtagtaaac gcaagcctgt gacggctaat tcacgacaga caatgatcgc
    58021 tactacccaa ccaggggcct ttccttggtc aaccaacatg ataaaagcag tcataactag
    58081 cattttatct gccaacgggt ccgcaaactt gccaaaatta gtgacaaggc ctcgcgcacg
    58141 ggcaattttt ccatctaacc agtctgtgat actagctaaa gcaaaaataa ctgcacctac
    58201 tagctgtgtg acagccagtg tggtgtctcc tacgttaaat tgtccccaat ctaaaggtaa
    58261 acctacaacc aaaatgaaaa tcgggatcat acaaattcta agtacagtta atttatttgg
    58321 taaattcaca ctatcgactc ctttcttccc tattctacgt gactatcagc gaagtttcca
    58381 ccgatattat ttacttttcc aaatgaattt attcaaagga gtatttttat tgaaattgat
    58441 ctttttgaat taacgaagaa ggaccgcgac acagatttgt cacgatcctt cttttttata
    58501 cctacaagta aacagatgcg taaactaatt tatacgatca ttctgcgtat tgaagagtaa
    58561 ggttcacatt ttttggactc tgattgtttt cccctggatt aactggtacg gattctccat
    58621 tcgctttgat cgttgcattg cttgctgcac caatcgtgat ggtcgcattt gttgctgttt
    58681 ccggtaacac ggtactctgt gtttcatttg ctgccagtgt cccttgataa acataggcat
    58741 tgtctactag cacacctaac catacacgat tgacagcagt aaattcaagg gttacaggct
    58801 tggtagcgtc tgtgatattt actgcgatgg cactgccaga atcttctcct gtagctattg
    58861 ccattttctt ttcttcactt gattttgttg ttgattctac tgtagaagac tctttggtct
    58921 gcgtgctttg ctctgaggaa gaggactcct cgactgatcc ttctacttta agcgaagaag
    58981 ctgtgtctcc gattattgga tcagcttgac gatcttgcca agtcatatag cccacgacaa
    59041 cgacaatcgc caaagcaacc aatcctaata aaatgacagg aagacttgtc caaaagcgac
    59101 ttggatgcga ttcttcctga tgcattgctt ttctagaagt acttactgtt tcaggctgcg
    59161 gacgttcagg gaccgatcct gtcaatttgc ttttcccatc aaaaacatcg actaaatggt
    59221 ctccatcttc tcctacagct tcagcgtatt gccgaataaa tgcccgcacg taaaatttac
    59281 caggcaattg gtcaaaatca tcattgtcga ttgcttccaa ataacgtttt tgaatttttg
    59341 taatctgctg taattcatct aaagatattt ttttattcag gcgtgcttgc cgtaattttt
    59401 ctccgatggt ttcaaaagcc actcgttcat cttctccagt ctgtttgatt ctccgaagca
    59461 tctgctgttg caacgaaaga cgttatgttt gggtgctgtg acaaaagtca tgtcacagct
    59521 ccttttttcc gaataaacat tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
    59581 aataaatata agaagctgtt ttttgaactt gttccttgtg actcggagtt aaacggcagg
    59641 ctcacgacct ctttcttaaa cggtgttcaa tcagctgttc ctcggtatta gctcaaaaac
    59701 cggcaaaata taaggagata tttttccgta tgtttctcta atactcaggt caaaacgctg
    59761 atttcacaac ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagtccaa
    59821 ccaagttaaa aacattaaga agctgttttt acttggctgt tcttattact tgatgcaggg
    59881 cagctttttc acaacctctt ggtacacggt gttccagaag tagcttcttc ggcaataagc
    59941 cgaaatatca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt tcttgaagct
    60001 gaccacttct gtcacaacct ctttgattac ttcgtttgat tttattttaa tataagttga
    60061 ttaaaagaga gcatgatttg ttttattttc tcactaattt ttccaacaca actaagaata
    60121 ccataaaagc tgattttgga ggaggttcct actacaagtc taaaacgaaa tttaagactt
    60181 ttcctcataa aatactggtt tattttggtc tcatgtaaaa ctcgctgaag gcctcttcac
    60241 ttataaatgc ttccccagct gccagtacgt ctttcatttg gatcgaatcg atgatttcag
    60301 gaagatcaaa taaagttcga tcgccaaata aactttgcgt aaattgattg gcaatatatt
    60361 cgatcgaatt taatgattgg aaatattgtc caagcatttt cttcttcagc aaatcgagat
    60421 ttgtttctga cacttccgga tcatcagcga atccaagaat gatttctttg actttttctg
    60481 ctgctttctc tggttcgtcc gtatctccgc tgaagtccgc aaagtgaaat tcacgatcca
    60541 agctgaattc aaaaccaaag ctgtcatcga taattccttg attgtacatc gctagatagt
    60601 ttcgagaagt attgcctaaa atcatttgga acaacagatt gattgctgtt ttatagcgta
    60661 acagttctgt tccttcttgc ggcaatgtgt ctaatccttt aataccaagt acaaatttat
    60721 ctcgtgtaat ggctgcttcc aatgcacttt gtttgatgat ttcttttgtg ttttcaggga
    60781 aataacgtac aatttcttgc tttggaggga aattttttgc ttcttggttt tcccgaataa
    60841 gtttcatcaa tttctcaggc tccatcttac caactacaaa taaaaccata ttgcttggct
    60901 gataaaacgt ccgatagcac gtatacaagt cttgagctgt gattttgtcg atactttcaa
    60961 ccgtgcccgc aatatcgata tgcaatgggt gtgtaggata caagttattt agtatgccaa
    61021 aaaacatccg ccagttaggg tcgtcttcat acatttggat ttcctgaccg atgattcctt
    61081 tttccttgtt tacagtttct tctgtgaagt aaggtgcttg tacaaaatcg atcagagtcg
    61141 tcagattctt ttctacctga tccgtcgtag aaaacagata gctggttttc gtaaaacttg
    61201 tgaaagcatt ggcggaagct ccttgtttcc caaataattg aaagacatca ccatcttctt
    61261 tttcaaacaa cttatgttct aaaaaatggg caattccatc tggaactttc accttttctt
    61321 tttcaccata gggaataaat tcgttatcga tcgaaccata attcgtactg aacaaaccat
    61381 atgtcttgtg atagtcattt ttaggcaaca aatacacggt caaaccgttt ggcagtactt
    61441 catgataaag tgtttcattg atttgctcat attctgtttt attcatttgc atttcctcct
    61501 gctaaaaaga agattgcctg caattcgatt tgctcagcta cttgttgtat ctctttgatc
    61561 gttacgctct ccatacgttt caaccattct tcatcagata attttgtttc cggcagccag
    61621 ctgtccaaaa aagaagcttc gattgccgct tgcggagagt ctagagaaag cagatattgg
    61681 tttctcagca ttgcttttgt ctgagacagt tccaactctg ttatttcacc atttcgcaaa
    61741 ctttctaatt gctcgtgaat cagatgaagt acttgatttc ggttcttttc atcgataccg
    61801 gtttggacac tcatgaatcc tcggaacgta tccacgctac tagaggcata ataagctaga
    61861 ctttctttct ctctgacatt catgaaaagt ttagagtgag gaaaaccgcc aaataaaccg
    61921 ttaaagacca ttagcgcaaa acgttctggt tcatcgtaat acacatttgt ctgataagct
    61981 aggttcagct ttgcttgaac gattggctca cgtacttgtc gttccttcac gatattcact
    62041 tgaggttggg tataaaacag atctggataa actgtttccc gcgactcaaa tggtaattgc
    62101 ccaactgctt cagctgcttt gtccggatca acatcgccga caacaaaaat gtcgatttga
    62161 tcatttgcca tcatttcttg atagtaggac gctagcgaac tagcagtgat cttgtccaaa
    62221 tcttcgacta cgcccaaccc tgggatcttt tgttccgggc tgttttcaaa ataaagttct
    62281 tgcaaggcat aggaagcaaa agtttgttta tcttccttca aactttccaa atatagacgc
    62341 agattgttct tttccaagtc aaacgtcaac tgatcaaact gatgattttt aatatttgga
    62401 taaaataaaa cctcttttaa aaaatctacc gcttgagaaa aaaggtttgg atcattgaca
    62461 tattcaccat tcacaaaact gatccctgcg tttagccaat gtaaatttcc tttttttcta
    62521 actgataatc caaagcttgc gccataaagc tctgcaagtt gcgcacttaa ctttgtctga
    62581 tccgaataat tcaaactatt tgtttccaac atgctgctga gaagtgaacg tttcgtgatg
    62641 acttcttgtt gcagacgcgc agtaaaacgg ataaaaatcc ggatcgtttt gtattgtttt
    62701 gttggtaaga catgaagatt cacgccttct gccaattgat acaccatatt tatatgctcc
    62761 ttttcacagt tgattgcccg cttactcttt taatgggtca acctgccttt tttacttatt
    62821 cctctgcttg aaatttataa gttcaggcaa ttcgccgttt tttctaaatg atgttacact
    62881 ttatagtata gcatagatgt tttttatcaa aagaaacaga cggctaaaag cgtatattgt
    62941 ttttttattt tttatttttc gatatactaa agacaaataa aagaagggag ggtcattcat
    63001 gatcaaagaa ttcaaagagt tcatcatgcg tggagatgtc ttggatcttg ctgtcggcgt
    63061 tgttattggt agtgcgttta caagcatcgt aaaccaagtg gtgcaaggct tgatcacacc
    63121 actaataggt tggtttgtcg caatgatcac aggtacttct gatttagaag gagcactttc
    63181 aattcttgac tggtcgccga caaaaggcgt cacatttgcg tttggtaacg ttattagtgc
    63241 tatcattaca tttctgatca ctggttttgt cttattctta gttgtcaaag cggcaaaccg
    63301 tgcgaagaat ttacgctcca aagaagagca agtggaagtg gaagaaactc ctactgcaga
    63361 agattatctt agtgacatac gcgatcttct tgccaaacaa gtggcagaag acaatacaca
    63421 tccagtagag caaacaaatc tttccgatac ttctaaataa taaagaatct aaaaaaaaga
    63481 aagccgattt tcagtgtcgg ctttcttttt ttagattctt aacttgctac ttgttccttt
    63541 ttcatgtcga tatgtggaat atcatcttcc aaatacacat ctgagattgc cttgaatcca
    63601 aacgactcat aaaaagcttg taggtattct tgtgcgccga tcacgattgg tttttctgga
    63661 aaatttttct ggatcatgtt aatcgtttct tgaacaatct ttcttcctaa accatcttta
    63721 cggttgtcct gatgaacaag gacacgtcca aaatggatac tctccgcttc ttcatatact
    63781 cgcgtgtagg caaggatctt cccatcagta tcttgaaaaa acgtatgcca agcttctcca
    63841 tcaatgtcat caacttcttg ataaggacac tgttgttcca caacaaaaac tgcgattcgt
    63901 tctttgacga tcgcgtaaaa ctctgctgtt gacaattctt caaatttctt tacctgatat
    63961 tccactaagc aaacgccccc tgctttttta ttcttagcat accgattcgc acacaaaaaa
    64021 gcaaacgaac cttacgaatc tcaggctcgt ttgcttttta aactgcttca gttaaaaatt
    64081 cgatctcaac tgtccgagta agtacatctg aatagctgta agatactcgt tcaaaagaat
    64141 tttcttcagg atccaaatca acaacgaata ctgaaggata ggtttctgtt aaaacgccgc
    64201 ggcgttctgt ttgacgcttt cttcctgtct gagcaaccaa catgattggg ctgccgatac
    64261 gaccttctaa atctttcttg attgaagcta aagttgttgg catacagttc acctctacta
    64321 tcaactatac cacatatttt taaaattttc aagtttacca taaaaaaaaa agaaatgcaa
    64381 taaaaataaa taagaagctc attaagattt ttctaaatta ttcctcatta taaaatttca
    64441 agtgtttttt tattttgagt tttactctcc cgtaagcgct cattacttgc ttgtgatcca
    64501 ttgctaaaca ttcagccatg tctacaaaat caacgccttg catataataa tgaaaaattt
    64561 tagcttctat ttttgaaaac tggatttcgc aattttcgat tgcttctttt aataaaagat
    64621 gctgaattgc taaaggttct tgcaatgtga tctctgctaa aaagtctggt ccttctgtct
    64681 ctattttttg gtcgattgag acttcatctt tttgatcacg acgcttcagc gcgttctgct
    64741 tcctcaacag agaatagatt tgattgctta taacgctttt ataataactt ccaaagctaa
    64801 cacctttgct tttttcgtaa gttctcaatg cctgatataa agcgatcctt gcttcttgtt
    64861 cccaatcctc agaaacataa tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg
    64921 gaaaatattt ttgatacagg gcagcaaatg cttcttcgtc accattacgt gcagcgcgca
    64981 ataactcctc agacataaaa taattcctcc ataaattcgt ttatggagga atcttatcat
    65041 caatgattca tcgaactgat tagaacgata tgttatttat tttttctcat taaatcgtcc
    65101 aatttttggg acaatttttt taactgctct tcattccatg gagaattacg tcggaaatca
    65161 ataaaatgca tatctttatt ttcttgggct attgtttttt ccgttttttt tatcgtctta
    65221 tataattcat aagcagaagt tcgtaatgct ccttgggaaa agatcatcca ctgttctgct
    65281 aaatcgcttg tcgccactgt cacttgtgtc aaacggtcat tcagctgacc agcgattctc
    65341 tcgatataac tgtcagccgt ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc
    65401 ttataatttt gttggatgcc cggaactagt tgggcatcga agacaacgat gacttccatt
    65461 ccttcatatt tcgcataatt tgataaacga tgtaaaagag cttctcttgc atccgccatt
    65521 ttgtcctgct ttttaagctg gacaagttcc ggccacgaac caatcatgtt gtagccgtct
    65581 acaatcaaca gctgtttttt catggtctac tccccctgac gttgggaaaa agcctgatac
    65641 ataagcaaac cagcagcaac actggcattt aagctctgga cgtgcccggt catcgggatc
    65701 gtcagcaatt catccatttc ttttttcaat cctggactca ttcctttgcc ttcattacca
    65761 atgactaaag caattgatcc tttggcattc catttttgga agtttgtgcc ggtcatatct
    65821 gtgccaaata cccaaaatcc tgtttctttg agctgttgca cagcttgtac caaattcgtc
    65881 acgcgtgcaa cagggacatg ttcgactgcc ccagtggaag tctttgttac gataggtgtg
    65941 attccaactg ctcggtgttt tggtatgatc acaccatcga cgccacttgc gtctgctgtc
    66001 cgtaaaatcg acccaaaatt gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg
    66061 tcttcttttt tctcttttgt tcgttcaatc agttggtcaa gggataaata ttcataaggt
    66121 gtaatcgcaa gaacgactcc ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt
    66181 ttaggaaccc atttgactgg cacagcttgt tcacgtgcga tttctttcag ttcttctact
    66241 ttttctcctc gtgaatcttc ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct
    66301 tctactgcgg catggtgccc aaagacgaaa ttatcttcta atgcttcttc attttgatca
    66361 gaaactgact gatttcgtcc agtttgcttt ttatttgaat atctattttg ttttttgtct
    66421 tcaaatccac gtttcgattg atgtttgttt gttctttctt tacccatttt tttcaccaac
    66481 tttctgaata caccagcgga tcaattcttc catccgctcg gtttgttttg tcaaatgcag
    66541 atagcccatg agcgcttcga accctgttgc gacccgatac gtcgtaacat cagcattttt
    66601 tgcgctcgta tggcttttag catttcttcc tctgcgataa taaagttctt cttcttctgt
    66661 caaaagatgt tcttccagca tttgctgaat caaaaaggct tgtgcattcg cagaaacata
    66721 attcgttgcc gcacgatgca gcttattggg ttttgtttct ccttgatcaa tcaggtggtc
    66781 acgaacatag atttcgtaaa tcgcatctcc aacataagcc aaggctaaac cgttcaattg
    66841 tgtgtaatct ctcatgcttc tcttctccat cgggttcctt gcggtgtatc ttctaataag
    66901 atcccttttt ctttcaacaa atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt
    66961 cttgcttgat ttcgttcttc gatcaattgt tcaatctctt catctaataa ctcttctgct
    67021 gtaaataaaa taccgaagat cgaaagccat tgcgagaata aagcttctcc ttgtgccaag
    67081 acagcggcag aaactttcgg ctggtctaga taagtgttca gccacttagc aagctcatag
    67141 accactgtga tcccatttgc tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt
    67201 tctaaatttt ctaacaaagc gattttatcc gcatcatctg ccaaattctc tgaggcagtt
    67261 tcttggcgga atttcaaatt gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct
    67321 tctttcatcg tcgtttcact gtagcggatc ggacgacggt attgtgtggt cgccatgaag
    67381 aaacgcaaga cttgtggatc aacgtttttg atcatttcat gtacagtgat gaaattccct
    67441 agagatttac tcattttttc atcgtcttcg ccaatcgtta catagccatt gtgcatccag
    67501 taattagcga attttttccc tgttttcgct tcactttgtg cgatttcatt ttcatgatga
    67561 ggaaattcta aatcttgccc gccaccatgg atatcgatcg tttctcctaa atgttttgtt
    67621 gccataacgg aacattcaat atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa
    67681 gaaatctcgc caggttttgc ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc
    67741 tgctgttctt cccctgtacg ctgacttgct ccgacttcca gttcatcgat ggattggtca
    67801 cttaatttcc cataattttc aaatttacgg gtacggtaat acacatcacc tgaagattca
    67861 taagcatagc ctttttcaac caacacttga ataaatgcta aaatatctgg catatgatcc
    67921 atgactcttg gatgcagtgt agcaggttcg acattcaacg ctttcgtatc ttcttcaaat
    67981 gctcggatga aacgatcagc aacttctggt gctgtaatac ctaattcgtt tgctgtacgg
    68041 atgattttat cgtctacatc cgtgaaattc gatacgaaat cgactttata gcctcgatat
    68101 tcaaaatagc gtcgaattgt atcgaaagca atggtgctac gagcatttcc gatatggata
    68161 taattataca cagtcggtcc gcagacatac ataccgacat gtcccttttg tatagggatg
    68221 aattcttctt tttttctggt caatgtattg tagattttta tcattctgat ctcctcactt
    68281 tttctccttt gattcgaacg acttttgctg gtactcctac cgctgtagcg tcgtctggaa
    68341 catctttcaa cacaacggca cctgcaccga ttttggcgtt ttttccgatc gttaccggtc
    68401 ctaatatctg cgcattcgca gagagcatgg ctccttgttt aacagttggg tgtcttttac
    68461 ccgtttcttt tcctgtgccg cctaatgtta cgccatggaa taaaatcaca tcgtcctcga
    68521 tttctgcggt ttcgccaatg acgattccca ttccatggtc gatgaacacg ccagttccaa
    68581 tcgttgctcc tggatggatc tcaacaccag ttaggaaacg ccagaattga gcattgatct
    68641 tcgccaataa aaagagccgg tgctgatata aaaaatgaga gaaacgatgc caaaacaagg
    68701 catgaaaacc agggtatgtc aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc
    68761 tctttgctgc atcaatcgct cgggtaaacc aactcatgac tttccactcc tttcgtaaga
    68821 attttatgta ggaaatcatc ttcttataaa gaaaagaagc gccttttaaa taagtttcct
    68881 tatcaaaaga cgctttccgc gtggttccac ttttcttcat aatcaatgat tatctctgac
    68941 agctaacgcc tgttatacgt tcttggctac tttgtttcct ataaaacagt ttttcctgtt
    69001 ttctgtgttt cgccaagacc actcccagag gcatttcggc aaccattcat tgataccttg
    69061 caccacccgg tatctctctt gtaatgatca gctgcttact tttttctgtt catcgtgttt
    69121 agttcagtac ttgatttaaa tgtgctaatg atttttcacg accaagcaat tcgatcgttt
    69181 caggcaattc tggaccatgc atttgtcctg atacagctac acggattggc atgaaaagat
    69241 tttttccttt tacgccagtt tctttttgaa cagctttgat ggcagctttg acagttggag
    69301 catctactac ttccatttgt tctagctgtg ctttgaatgc gtggagaaca gtaggaactg
    69361 tttcaccagc aagtacttct tttgctgctt cattcaatac aggatgttca ttgaaaaata
    69421 gcgtagacag atcaacgatt tctgcagcat agctcatttg aggttgatac aggctaacga
    69481 tcttcttcac ccattcgatt gtcttttcat ctgggttttc tgctacacgt ccatcagcga
    69541 ttagataagg cagacacatg tcagtaaatg catctagatc cattgctttg atgtaatggt
    69601 tgtttaccca ttgcagtttt ttcgcatcga aagctgcggg tgatttactt aggcgttttg
    69661 gatcgaacat tttgatcaat tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc
    69721 agcccaataa tgcaataaag ttgaacattg catctggtag atagcctaat tcgcgatatt
    69781 gttcgataaa ttgcaagatt gattcgtcac gtttgcttag ttttttacct gtttcactgt
    69841 tgatgatcaa tgtcatatgt ccgaaggttg gtggtgtcca gccaaatgct tcatagatca
    69901 tcagttgttt tggtgtattg gcaatatggt catctccacg taaaacgtga gtgattttca
    69961 tcaaatgatc atcgaccgca acagcaaaat tataagttgg cataccatcg cgtttttgga
    70021 tgacaaagtc gccaccgata ttatcggatt cgaacgaaat agcgcctttc accatatctg
    70081 taaatgcgta ttctgtattg cgaggcacac ggaaacgtac aacagattct agaccttgtg
    70141 cttctttttc tgcttgttct tcaggtgtca agttcgcaca tgttcctgcg taatgaggca
    70201 tttctcctct tgcgcgttgt gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc
    70261 atttgtatgc tcgattgcta gcaagcagct gatcaatcag cggttgatag atttctttac
    70321 gttcagattg acggtaaggg ccgtattctc caggattttc aggagattca tcccaattca
    70381 ttcccaacca agcaaggttt tccaactggc ttttttcgcc atcttcgata ttacgttttt
    70441 ggtcagtatc ctcaatacga ataataaagt ctccatcatt gtggcgggca aacaaataat
    70501 tgaataatgc agttcttgca tttccaatat gcaggtgccc agttggactt ggtgcatagc
    70561 gtacgcgtac tttcgtcatt ttcttcctct tctttcaaac tagactttga ctaacagcaa
    70621 aaattccgtc agttacggct tctcaaatat catttattta aagccactca gcacaaattt
    70681 taccttttct aaggtaaata gtaaagccaa ctggttgaat ttccttacca gttggctgaa
    70741 tttctttttt attttgattg tttagtcttt ttctctgtct cttttttatt gtcgattcct
    70801 cgtcctgcat gtgcaggttt agcaaagatc atgcgtccag cagctgtttg aagggcactt
    70861 gttacaacga cttcgatacg ttcattcatg taatgctgtc catcttctac gacaaccatc
    70921 gtgccgtcat caaggtaggc tactccttgt tggcgttctg tcccggcttt tactactaga
    70981 acattcatcg tttcaccagg gatgacgact ggttttacgg catttgccaa cgcattgata
    71041 ttaagaacag gtacattttg gaattcagag actttattca agttatagtc attggttaca
    71101 atgacaccat ctaaaagctt agccaatttg atcaatttgc tgtctacttc actgatatct
    71161 tcaaagtctc catcgtacat ttcgacagat ataccctctt ctttttgcaa ggcatttagg
    71221 atatctaatc cgcgacgacc acgcacacgt ttcaaactat cccctgagtc cgcgatgtat
    71281 tgtagttcgt aaagaacaaa attagggatc atcaaggttc cttctaagaa tccagtcttt
    71341 gtaatatcat aaatccgacc gtcaatgatc acgcttgtat ccaagatttt atatttatgg
    71401 aaattttctc ctgattttcg ttctaacagt tgactctcaa cttgactagc tgtttcttgc
    71461 tcgatttttt tgcttcgtga accaaaaact ttcttccatt cttcgattcg tgtcgttccc
    71521 attctcaatc ccagatagcc taagatgatc atcagtaaaa tcggcaatac actattgacg
    71581 aatggaattt ccatattgta aagaggggtc gagatcacaa cacctaaagt caatccgatg
    71641 atcgcaccga tcgcaccgaa gagaagataa gtcaagctga cctcacttag tttttgttct
    71701 acttgtttga taatagctga gatatgtttg gccaacagca aagataataa aaagaaaata
    71761 agtgcgccta acaggctgtt ggtaaatgta ttattcagcc atccgtttga ctgttgaccg
    71821 attgcctgcc aagctgaggg taaaaatgaa atacccaagc ttgcgccgac aatgatcatc
    71881 agcaaagtaa tgacacgttt ttgcatcgtt tttcctccgt ttcgacaatc atttattagt
    71941 tagcggaaca cacgcttcaa cgtttcagcc aaagttgcta ctccaactat ctcgattcct
    72001 tttggcgctt cccagttacc taagttgttt ttaggtaggt atacttttgt gaagccgagt
    72061 ttttggactt ctttgactcg ttgttcaata tgactgacac gtctgatttc tccagtcagt
    72121 ccaatttcac cgatgaaaca ttccgttggc tgtgttcctt tttctttata gcttgaagca
    72181 atactgacag cgatagctaa atcaatcgct ggttcattta attttacccc acctgcagct
    72241 tttaagtaag catcttgatt ctgaagaagc aacccagctc ttttttccag cactgccatg
    72301 atcagagata cccgattgaa atcaagacct gttgttgttc gtttggcatt tccgaacata
    72361 gtaggtgtga ctaatgcttg gatctctacc aaaattggac gtgtcccttc cattgccaca
    72421 acgatagcag agccagttgc accgtctagg cgttcttcta agaaaatctg tgaaggatta
    72481 gcgacttctt ccaatccatg ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca
    72541 aatcggtttt ttactgctcg caaaatccga aaactatgat gttgttcacc ttcaaaatat
    72601 aacaccgtat ccaccatatg ttctaacatt cttgggccgg cgatcgagcc ttctttggta
    72661 acatgaccga cgataaaaat ggctatccca tttgttttag cggttttgag tagttctgca
    72721 gtggtttctc ttacttggct gacacttcct gccacacttg tgatgtctgg ctgcgtcatc
    72781 gtttggatgg aatcaatgat aacataatca ggggagatat gttcgatggc acgactgatt
    72841 tcgttcatat ctgtttcagc gtatagataa aattctgtgt tgatacttcc gaggcgttcc
    72901 gcgcgtaatt ttatctgctc tgcgctttct tcgccggata catataagac ttttccgcct
    72961 atggctgcta attgctgaga aacttgtaac agcaaagtgg atttcccgat acctggatcg
    73021 ccaccaatca agaccataga ccctggcacc acacctccgc ctaacacacg gttcagttct
    73081 tctaattttg ttttgatccg aggttctttt ttagggacga cgtctgcgat ttttgttggt
    73141 tttgcttttt ctcctgtcaa acttgtccga gttctgcggt ccgttgtatc ttgttcgatt
    73201 tcttcgacca tcgtattcca ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac
    73261 acatacccgc aattttggca aacaaattgt acttttgatt tttttgccat tgtaccgcct
    73321 ccttttatcc taatcatgag acattaaatc aagcttaagt atctttaacg ttttatttac
    73381 tggaagaacc aaatccgcct tgacgttgag cagtcgtttg atcttgatct gcttttaaaa
    73441 acggcaaaaa gatcccttgg ccgatacgct cgcctttttt gatcactaca tccttgaaac
    73501 caaagttggt gaattggaac atgatatggc cttcatttgc ctcattattg taataatcac
    73561 tgtcaatcac acctactccg tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac
    73621 ggttagcaag ctgcaaaaat tcatcttctc ccatgtaagc tttgattcca gtaggcacga
    73681 gggttggttt caattgtttt tcattttctg atacatcttt tttcaatcca tctgcgactg
    73741 tttccaaccc ctttttccag cctgctttcc agatacttgg aatcacgacc tcttctgctg
    73801 cttcaaaatc atagccagca gcatgatgtg tagcgcgctg cggtagattg atattttgat
    73861 ctttatattt agaaataact tcaaatcctc tttttctcac cggttttcct ccctaaataa
    73921 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
    73981 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tgcaagttgt
    74041 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
    74101 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
    74161 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
    74221 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
    74281 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
    74341 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
    74401 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
    74461 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
    74521 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
    74581 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
    74641 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
    74701 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
    74761 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
    74821 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
    74881 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
    74941 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
    75001 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
    75061 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
    75121 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
    75181 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
    75241 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg atcggcatca tttacgaatc
    75301 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
    75361 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
    75421 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
    75481 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
    75541 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
    75601 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
    75661 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
    75721 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
    75781 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
    75841 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
    75901 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
    75961 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
    76021 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
    76081 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
    76141 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
    76201 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
    76261 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
    76321 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
    76381 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
    76441 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
    76501 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
    76561 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
    76621 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
    76681 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
    76741 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
    76801 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
    76861 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
    76921 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
    76981 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
    77041 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
    77101 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
    77161 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
    77221 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
    77281 acctcttggt aaacggcgtt caatcagctg accctcggta ttagctcaaa aaacggtaaa
    77341 atatgagaag ctatttttcc gttttgtttc tctaatactt aggataaaac gctgatttta
    77401 caacctctgt taaacggtgt tcaatcagct gtccttcggt attagctcaa aaaacggcaa
    77461 aatatgagga actatttttc cgtttgtttc tctaatactc aggacaaaac gctgatttta
    77521 caacctcctg
//
LOCUS       DACGLI010000005        75408 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.005, whole genome shotgun sequence.
ACCESSION   DACGLI010000005 DACGLI010000000
VERSION     DACGLI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 75408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.005"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(541..975)
                     /locus_tag="IXT22_000367"
     CDS             complement(541..975)
                     /locus_tag="IXT22_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861765.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(992..2197)
                     /locus_tag="IXT22_000368"
     CDS             complement(992..2197)
                     /locus_tag="IXT22_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAQ4861766.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            2891..3277
                     /locus_tag="IXT22_000369"
     CDS             2891..3277
                     /locus_tag="IXT22_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4861767.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            3371..3562
                     /locus_tag="IXT22_000370"
     CDS             3371..3562
                     /locus_tag="IXT22_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861768.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            4076..4408
                     /locus_tag="IXT22_000371"
     CDS             4076..4408
                     /locus_tag="IXT22_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4861769.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            4704..4859
                     /locus_tag="IXT22_000372"
     CDS             4704..4859
                     /locus_tag="IXT22_000372"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAQ4861770.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            5135..6475
                     /locus_tag="IXT22_000373"
                     /pseudo
     CDS             5135..6475
                     /locus_tag="IXT22_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(6716..8332)
                     /locus_tag="IXT22_000374"
     CDS             complement(6716..8332)
                     /locus_tag="IXT22_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4861771.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            8450..8668
                     /locus_tag="IXT22_000375"
     CDS             8450..8668
                     /locus_tag="IXT22_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861772.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            8863..9324
                     /locus_tag="IXT22_000376"
     CDS             8863..9324
                     /locus_tag="IXT22_000376"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4861773.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(9517..9756)
                     /locus_tag="IXT22_000377"
     CDS             complement(9517..9756)
                     /locus_tag="IXT22_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861774.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(9780..11303)
                     /locus_tag="IXT22_000378"
     CDS             complement(9780..11303)
                     /locus_tag="IXT22_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4861775.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(11321..11443)
                     /locus_tag="IXT22_000379"
     CDS             complement(11321..11443)
                     /locus_tag="IXT22_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4861776.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(11473..12456)
                     /locus_tag="IXT22_000380"
     CDS             complement(11473..12456)
                     /locus_tag="IXT22_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAQ4861777.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(12480..12629)
                     /gene="rpmG"
                     /locus_tag="IXT22_000381"
     CDS             complement(12480..12629)
                     /gene="rpmG"
                     /locus_tag="IXT22_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4861778.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(12650..13027)
                     /locus_tag="IXT22_000382"
     CDS             complement(12650..13027)
                     /locus_tag="IXT22_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861779.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(13059..13238)
                     /gene="rpmF"
                     /locus_tag="IXT22_000383"
     CDS             complement(13059..13238)
                     /gene="rpmF"
                     /locus_tag="IXT22_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4861780.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(13253..13522)
                     /gene="rpsN"
                     /locus_tag="IXT22_000384"
     CDS             complement(13253..13522)
                     /gene="rpsN"
                     /locus_tag="IXT22_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4861781.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(14045..15817)
                     /locus_tag="IXT22_000385"
     CDS             complement(14045..15817)
                     /locus_tag="IXT22_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861782.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINM
                     VPAFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     VQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(15771..17525)
                     /locus_tag="IXT22_000386"
     CDS             complement(15771..17525)
                     /locus_tag="IXT22_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861783.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(17635..18204)
                     /locus_tag="IXT22_000387"
     CDS             complement(17635..18204)
                     /locus_tag="IXT22_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAQ4861784.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(18222..19646)
                     /locus_tag="IXT22_000388"
     CDS             complement(18222..19646)
                     /locus_tag="IXT22_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4861785.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(19648..20316)
                     /locus_tag="IXT22_000389"
     CDS             complement(19648..20316)
                     /locus_tag="IXT22_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4861786.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(20446..21030)
                     /locus_tag="IXT22_000390"
     CDS             complement(20446..21030)
                     /locus_tag="IXT22_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4861787.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(21361..21594)
                     /locus_tag="IXT22_000391"
     CDS             complement(21361..21594)
                     /locus_tag="IXT22_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAQ4861788.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(21609..22559)
                     /locus_tag="IXT22_000392"
     CDS             complement(21609..22559)
                     /locus_tag="IXT22_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861789.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(22556..23398)
                     /locus_tag="IXT22_000393"
     CDS             complement(22556..23398)
                     /locus_tag="IXT22_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4861790.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(23400..24119)
                     /locus_tag="IXT22_000394"
     CDS             complement(23400..24119)
                     /locus_tag="IXT22_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861791.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            24811..24969
                     /locus_tag="IXT22_000395"
     CDS             24811..24969
                     /locus_tag="IXT22_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861792.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            25041..26267
                     /locus_tag="IXT22_000396"
     CDS             25041..26267
                     /locus_tag="IXT22_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4861793.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(26856..28304)
                     /locus_tag="IXT22_000397"
     CDS             complement(26856..28304)
                     /locus_tag="IXT22_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019035073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAQ4861794.1"
                     /translation="MDYEIQKFISEKEDQYFDRKSARIKPRDIIKHIVAFANADGGKL
                     VIGIEDDGTISGFKFQGAIDPDEYVLAINSMTKPNPTFKKEMKSIKNARGEDDILFII
                     DVEPSISHVIFNSNGDCFLRIGDKSVHQTHDQISKLEYDKGQRMFEDIEILDSTLDDI
                     DESLMDSYKKLKKAEAISTETILTGRGLMRNGHLTNAGMLLFGKNTFLALPNSRIRFL
                     RYDGKRNETGRRLNIVKEFDYEGAIPKLIESITRDVKTQLREFQYLNDDGKFSIIPEY
                     PEFAWFEGIVNALTHRDYSYKGDYVRINMYDDRLEIFSPGALPNIVTLQNMRRTRYAR
                     NPRIARTLSEFGWVKELNEGVNRIYDEMQLLFLNEPKYSEPNNNSVLLVLENSITSRH
                     LRERDRLDDYLGEFEVDSLSTSEKMIVSHLFNNEKISVKEASEVLKKGVGYSRKVLKE
                     MLRKKIIQWHGTSTKDPTQYYSLNRVKQSKIE"
     gene            complement(28450..29946)
                     /locus_tag="IXT22_000398"
     CDS             complement(28450..29946)
                     /locus_tag="IXT22_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAQ4861795.1"
                     /translation="MNHQEAKQFFLKTSSFFSTSLPNYIDLSVGIEKAVDLLKNKSFT
                     ELVRHKRSLSEAVDVNHRILANKDGNYAWRPLQILHPLVYVDLVNGITQKNNWNHIKN
                     KFEEFQADKRIECISLPVESISSKSDTAETILNWWENLEQAQISYALEYDYCIHSDIT
                     DCYSSMYTHTIPWAVHSKEWAKTHRKDTQGVGNLIDSKIRYLQNGQTNGIPQGNVLMD
                     FVAEIVLGYADKMLLNKIEKTEIKEFKILRYRDDYRIFSVRKDQAEVIIRLLSEVLSD
                     LNLKLNSNKTFLSDNIILDAIKPDKIYWDLKHASFTEKSNNKWKFKLSLQKHLLQVKL
                     LGDKYPNCGSLSKALSEVYTHRVSTLNKRPDDIYQLISILVNIMQKNPRTLEACIVIL
                     GKLFEFIAVEEINLYLDKILRKFVNTPNTDIVEIWLQRLSLIHSREKSYSAKLCKKVS
                     NPKGFTLWNSDWLKKGFDESGIVNETFISNLSLTTPAKDLELFISQYE"
     gene            complement(30118..30363)
                     /locus_tag="IXT22_000399"
     CDS             complement(30118..30363)
                     /locus_tag="IXT22_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861796.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            30468..31241
                     /locus_tag="IXT22_000400"
     CDS             30468..31241
                     /locus_tag="IXT22_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861797.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAKLYTEKVEQFFKSGANKDFSKISDYSENFFNETQDEIMNSTFMA
                     EDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDYEYSPDYLEKPLQHENNDINFR
                     FVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIKIF"
     gene            complement(31471..31719)
                     /locus_tag="IXT22_000401"
     CDS             complement(31471..31719)
                     /locus_tag="IXT22_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4861798.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDLMKNEKEDDFKVV"
     gene            complement(31818..32168)
                     /locus_tag="IXT22_000402"
     CDS             complement(31818..32168)
                     /locus_tag="IXT22_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861799.1"
                     /translation="MIFENESEEIGRMTEENKVDLLETLVINKKEFEQLFLDFFVQYD
                     RIYDFNSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFR
                     EFRNKIIGFSQTTK"
     gene            complement(32209..32703)
                     /locus_tag="IXT22_000403"
     CDS             complement(32209..32703)
                     /locus_tag="IXT22_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861800.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(32696..32998)
                     /locus_tag="IXT22_000404"
     CDS             complement(32696..32998)
                     /locus_tag="IXT22_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861801.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(33021..34358)
                     /locus_tag="IXT22_000405"
     CDS             complement(33021..34358)
                     /locus_tag="IXT22_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4861802.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQLTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEGELILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSKEVLTEIAIRHL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(34343..34840)
                     /locus_tag="IXT22_000406"
     CDS             complement(34343..34840)
                     /locus_tag="IXT22_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861803.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(34989..35327)
                     /locus_tag="IXT22_000407"
     CDS             complement(34989..35327)
                     /locus_tag="IXT22_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861804.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(35331..35516)
                     /locus_tag="IXT22_000408"
     CDS             complement(35331..35516)
                     /locus_tag="IXT22_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861805.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     MMKNELMNELSHIQKGA"
     gene            complement(35530..38082)
                     /locus_tag="IXT22_000409"
     CDS             complement(35530..38082)
                     /locus_tag="IXT22_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861806.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLNTVVIGLMVLSLVIIGYKMVTGKGTVDLKSVGMNVVMSIVLI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     MIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENSTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISTNIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNSGGNDQTEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMAS
                     ERATKPFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPI
                     RLSDRKDGAKIENADRIMSSSERMREAMKNIAESNTNYASAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKN
                     SNTGLEKSVKENLQNSTSSQDRRSVDVRENLHNTTSSQSGNRTVDVRENVQSSSTGQT
                     RTVDVRLNLQDTTSSQSGNRTVDVRENVQSSAPNQPKTVEVRETRAEASQGDKTQKIN
                     IVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSLFKK"
     gene            complement(38069..38287)
                     /locus_tag="IXT22_000410"
     CDS             complement(38069..38287)
                     /locus_tag="IXT22_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861807.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(38280..39020)
                     /locus_tag="IXT22_000411"
     CDS             complement(38280..39020)
                     /locus_tag="IXT22_000411"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861808.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(39153..40037)
                     /locus_tag="IXT22_000412"
     CDS             complement(39153..40037)
                     /locus_tag="IXT22_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HAQ4861809.1"
                     /translation="MIFMAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIV
                     EAYPYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFK
                     LLNLKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNS
                     QDQTNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKD
                     SIEREYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIA
                     KQEKASRLDMLETLKKIG"
     gene            complement(40198..40525)
                     /locus_tag="IXT22_000413"
                     /pseudo
     CDS             complement(40198..40525)
                     /locus_tag="IXT22_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40534..40731)
                     /locus_tag="IXT22_000414"
     CDS             complement(40534..40731)
                     /locus_tag="IXT22_000414"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861810.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            40898..41272
                     /locus_tag="IXT22_000415"
     CDS             40898..41272
                     /locus_tag="IXT22_000415"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861811.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            41362..42528
                     /locus_tag="IXT22_000416"
     CDS             41362..42528
                     /locus_tag="IXT22_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4861812.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(42627..43019)
                     /gene="rpsI"
                     /locus_tag="IXT22_000417"
     CDS             complement(42627..43019)
                     /gene="rpsI"
                     /locus_tag="IXT22_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4861813.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(43035..43478)
                     /gene="rplM"
                     /locus_tag="IXT22_000418"
     CDS             complement(43035..43478)
                     /gene="rplM"
                     /locus_tag="IXT22_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAQ4861814.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(43997..44464)
                     /locus_tag="IXT22_000419"
     CDS             complement(43997..44464)
                     /locus_tag="IXT22_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAQ4861815.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(44584..46122)
                     /locus_tag="IXT22_000420"
     CDS             complement(44584..46122)
                     /locus_tag="IXT22_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAQ4861816.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            46202..46888
                     /locus_tag="IXT22_000421"
     CDS             46202..46888
                     /locus_tag="IXT22_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAQ4861817.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(47089..47616)
                     /gene="msrA"
                     /locus_tag="IXT22_000422"
     CDS             complement(47089..47616)
                     /gene="msrA"
                     /locus_tag="IXT22_000422"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4861818.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(47700..48377)
                     /gene="pgmB"
                     /locus_tag="IXT22_000423"
     CDS             complement(47700..48377)
                     /gene="pgmB"
                     /locus_tag="IXT22_000423"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4861819.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(48374..49504)
                     /locus_tag="IXT22_000424"
     CDS             complement(48374..49504)
                     /locus_tag="IXT22_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4861820.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(49504..51687)
                     /locus_tag="IXT22_000425"
     CDS             complement(49504..51687)
                     /locus_tag="IXT22_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4861821.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(51684..52709)
                     /locus_tag="IXT22_000426"
     CDS             complement(51684..52709)
                     /locus_tag="IXT22_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4861822.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(52754..53581)
                     /locus_tag="IXT22_000427"
     CDS             complement(52754..53581)
                     /locus_tag="IXT22_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4861823.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(53578..54645)
                     /locus_tag="IXT22_000428"
     CDS             complement(53578..54645)
                     /locus_tag="IXT22_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAQ4861824.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(54671..55507)
                     /locus_tag="IXT22_000429"
     CDS             complement(54671..55507)
                     /locus_tag="IXT22_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4861825.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(55504..56373)
                     /locus_tag="IXT22_000430"
     CDS             complement(55504..56373)
                     /locus_tag="IXT22_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4861826.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(56443..57726)
                     /locus_tag="IXT22_000431"
     CDS             complement(56443..57726)
                     /locus_tag="IXT22_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861827.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(57740..59425)
                     /locus_tag="IXT22_000432"
     CDS             complement(57740..59425)
                     /locus_tag="IXT22_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAQ4861828.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            59700..60725
                     /locus_tag="IXT22_000433"
     CDS             59700..60725
                     /locus_tag="IXT22_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4861829.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(61320..64973)
                     /gene="rpoC"
                     /locus_tag="IXT22_000434"
     CDS             complement(61320..64973)
                     /gene="rpoC"
                     /locus_tag="IXT22_000434"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAQ4861830.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(65052..68669)
                     /gene="rpoB"
                     /locus_tag="IXT22_000435"
     CDS             complement(65052..68669)
                     /gene="rpoB"
                     /locus_tag="IXT22_000435"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4861831.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            69397..70365
                     /locus_tag="IXT22_000436"
     CDS             69397..70365
                     /locus_tag="IXT22_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861832.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            70383..71288
                     /locus_tag="IXT22_000437"
     CDS             70383..71288
                     /locus_tag="IXT22_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861833.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            71285..72091
                     /locus_tag="IXT22_000438"
     CDS             71285..72091
                     /locus_tag="IXT22_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4861834.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            72248..73216
                     /locus_tag="IXT22_000439"
     CDS             72248..73216
                     /locus_tag="IXT22_000439"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAQ4861835.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(73533..74057)
                     /locus_tag="IXT22_000440"
     CDS             complement(73533..74057)
                     /locus_tag="IXT22_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAQ4861836.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            74344..>75408
                     /gene="scm"
                     /locus_tag="IXT22_000441"
     CDS             74344..>75408
                     /gene="scm"
                     /locus_tag="IXT22_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4861837.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        22977 a        15019 c        12082 g        25330 t
ORIGIN      
        1 taggaatctt actaacctta tgttaactaa tttacttaga gaatttcatg aacattacaa
       61 caaaaaaagt acatttcttc atgttttttt cggatatttg tgctttttaa ccattcagca
      121 gctgaaaaca tataaaaaga tatgtatgta ttctttctga aattaagttc atttctatgc
      181 gatgaagcat gttttcaaaa tattaccctt tcttagatta aacttcagag tattcaaata
      241 acggaataag gagccttatc ccgcattact gaatgagact gtgacataag taaaaaggtg
      301 acttcaaatt ccttcttcgg aatttgaaat caccttcttt ataattataa agtatcggtt
      361 tcacagcatt tctgaatgat tcctagaatc ttaaacgaat gattggagtt atcaacattt
      421 tttcactcgt ttttagcgaa acaaaaaatg acatttgtca cagcctcatt aaattattga
      481 ttctttttct ttataattga attgtccata tttaaagtgt ctagtactct acatgaataa
      541 ttaattgctt tcactcaaat acttataatc tattaacttg tagttgttta acttttctga
      601 aaaagttaga cccacgtaat aatcttccca gctttctctt tcaattaact gatccaattt
      661 ttgataatcc ataaattcat catgtatcaa aaagaataaa taacttgata ttttagcatc
      721 tagcttaatc agattaaata atgtttgttt aaaattgcta ccattaatat gactgataga
      781 ttctctagct tcttcacata aactttttac tttattaatt actactttgt catattcatt
      841 taacacacta ttattaccat tacttagacg ctcagattct acgaaacaac tcaaatcaga
      901 aatttcccaa aaaaattttt tgttaaaatc caatttcctc aactcctcca aactacgtaa
      961 atgatatagt ctcataataa aataaaacct ctcagctaat gttgttgaaa ttgtccacta
     1021 aacctaattg atattgctta ggagatacac ctgcgtactt tttgaatact ctcgaaaagt
     1081 gtgaagaatc tgaaaatcct aaacctaaag aaacttcact gatagtatgg tttgatttca
     1141 acattatttt agccgtagaa atttttcgct tagagatata attataaatc gtaatatgca
     1201 tttcattctt aaagctttct cttaatttag tttcacttac agaaaaataa ttagctattt
     1261 cctttacagt aattctttta tagatattta agccgatgaa ttgaacgaca gaagaaatta
     1321 agggagaaag atgctctatc ttagtttttc cgatttcctt agtataataa acaatcccag
     1381 aatccctcac ttttaagacc tcaggtaacg atacagctaa ttcgttttct tgtatcaaag
     1441 catctctact ttgatacgct tctattatat ccattcctaa tgttatagac gtttgtgcta
     1501 acttttcaaa aacaatgata gaataatttt tttcagaccg aatcgtatct ccactaacac
     1561 ttggaattat tccattactc agattaaaaa ccatgttttc taaatttcga atatctccat
     1621 ttttaacata ttccagtatt ttattttcat aaagaaacag atatatttct ggatcgtaat
     1681 tttgtgataa cagattatct attttgattt gctcgatagt tttacttaga ttttctgtat
     1741 attcaattaa cggttcatgg aatagatctt ctatttttcc agtaaaaaaa taatgaacta
     1801 aaatcagaat atctcgaatg tctcctaaag aatacaaagt caaattttgc aatgaattat
     1861 agagtcgttc tctatcagcc attgcaacat tcaaattgtt catttttagt ttaaaaaaaa
     1921 ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt
     1981 atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa
     2041 tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat
     2101 actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat
     2161 gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct
     2221 acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct
     2281 aacttacttc attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt
     2341 acattttatc accgagaact catcattttt catcatgatg aatactattt acatatatct
     2401 agttcaaaga caataattat tatgatccgt tattatctaa gcactataca gataatagga
     2461 atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt
     2521 gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat
     2581 ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa
     2641 aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa gatatatgaa
     2701 ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca tttttgaaaa
     2761 taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc agcgcagcat
     2821 aattgcatta gcttcttttc gtgttttttg cctcttttcc ctttaaatct taatggagga
     2881 ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc gattctttga
     2941 aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa ttcaaaaaca
     3001 tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa aatttaaaca
     3061 accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag caaaaatcct
     3121 tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct ttgataaaac
     3181 tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa atttaaaaca
     3241 tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata actaattttg
     3301 tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc catgggaaga
     3361 aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg gaaatgaaga
     3421 agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat cctggagaac
     3481 tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc tagctatctc
     3541 gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt aaaaagatag
     3601 tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa gtatcgattt
     3661 tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta tcaacgtttt
     3721 ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa aattacttta
     3781 tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac ttcaacgagg
     3841 acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg tagatttatt
     3901 caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga attttggttg
     3961 ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat actaagttgg
     4021 gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa ctctattgag
     4081 aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg agaaaaaagt
     4141 aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt cccgatgggt
     4201 ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa gattacctga
     4261 taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg aagacgagtg
     4321 ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact ttacgatgaa
     4381 ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa tttatgcaca
     4441 agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaacaatcaa agaaatggta
     4501 aaaaaatgtt gaatcgataa tttgaacaga accaaattga tgctgtttgg gtgatggata
     4561 ttacttacat tccatgtaat gacggtcgcc tctatttgtc cacctatatt gacttagcaa
     4621 ctcgtattct acgttactat atggtagatt cacacatgaa aaaagagatt gtcgtccgtc
     4681 cattacaaat ttattaagga gaattgccta cggtaattca ttccgataga ggtagccagc
     4741 atcggtcttt tatttatcaa gagctgttga acgaccacca catcacacat tcagtgagcc
     4801 aaactgggac tcctgttgac aatgcagtaa ttgaagcgtt tcatcgatca atcaaatgag
     4861 aattaatcga ctccaacaaa tataaaagta aaatagagat gaaggtgtta atccaagatt
     4921 atttagaaga ctactaccca aacaaaagaa tccatacaaa atttatgatg actccttgac
     4981 aatttgaagc gaagaaaata agggatctat aatatctagt gttggtgacg ccttctgttg
     5041 ccaatacttt ttcttttttc taataaacgc aaacagacac cttaaaatcc tttagaataa
     5101 agtcgacgaa aaccattcaa aggagtgttt caagatgtcc tattcagagt ttaccaaaga
     5161 gttactagat attctagacc taaatcttat ctttcatgaa gatgcctttc gcaaagagcg
     5221 aatcaatgac gaaacatgtt ttgtttttga tggcacattg acctatcaac cggaggaatg
     5281 ctttcatcgc cactatcaaa atgaacaaac gatcattaaa tagggctgga aaaaagtatc
     5341 catcttattg aatgatgtca gtaactacaa gaccattctg cggattaaca aacagcgctt
     5401 caaatgtaaa cactgtggaa agactttttt agcagaagat tcagttagtg atcgtcgctg
     5461 ctccattgct cgcagagtca aacaagccat tcttgagcta ttaagcgaac ctctttctat
     5521 gtctttgatc gcacgtatga agcacatttc tccgaccact gtcattcgaa tacttcgcag
     5581 ccttcggcct aaaaccattt ctttgagcca gctgttacca gaagtggtgt gtttcgatga
     5641 attcaaatca gtgaaaaatg tctcgggagc catgagcttt gtcatgatgg acggcaagac
     5701 ccatcaactg attgatattg tggaaaatcg gcaactcaat cctttacgcg actatttctt
     5761 gcgctaccct ataaaagtcc gtgaacaagt gcgtctagtg gtttcagatt tctatacacc
     5821 ctatcgcaca ttggtgaaag agtgttttcc gaatgcccga atcgtcgccg atcgctttca
     5881 tattagccaa cacattggtc gggcttttac caaccaccga attcaagtaa tgaagacctt
     5941 taaaaaaggg gatcgtcggt cgaagcactt aaagaaatac tggaaactac ttcaaaagaa
     6001 tgcgtgggaa ttgaaaggtc agcatcgcta ctggcgtccg tcatttcgag atcatctgac
     6061 agaagcagag atagtcgatc ggctattatc ttatgatgat tccttaaagc gaggctacga
     6121 agtctaccag gattttcttt ccgttatcag aagacaagat gttcctgaat tcgtcgcgct
     6181 cctaaaagaa gactacaagg agttgccaga gcactaccaa ccagtgttca cgaccttcaa
     6241 gaaataccaa acagaaatca aacgagcgtt gcgcgttccc tattccaacg gccctataga
     6301 atgtttgaat aaccatatca aagtactaaa acgaattgcc tatggctata gaaactttca
     6361 aaactaccga gaacgaatct ttttatatcg aggaaaatat tttaagaaaa ctaagaatac
     6421 tacccaactg actaaagcca gaacaacaac acggctagac aagatagctg tctagccgtg
     6481 tgagtatctc gattattcta ttgaatttct tcaccaacac tcattgacga agagccaaaa
     6541 taagtaatct aaccgactgt taactaaacc attgcaggtc ccgttaaaga tacttgtgcc
     6601 tgttgtcacc gcttcttttt cttgtccaca agcgcttaac acacttaata aagcccctgc
     6661 tattattaat aataatatct ttttcttatt aaaaacctcc tcatctattt ccagattagt
     6721 aaatgtagta atctgtgctt tcttttttct caatactaat aactaactta tggggtaaac
     6781 aaatactcgt ttgaccgggt tttgagatcc atccagttct aaccgcgatt tgatcaggac
     6841 tattatcttc tttaactcga attcttccat ctttaatctc aacaatatta tattgtccct
     6901 tcgcaggatg ataattcacg agtttatgat tgatcttatc caaatcgaag cgatccattt
     6961 ccttgccatc aattcgaacg atggcatatt tgatagcatc ttcagttgtt tcattctcct
     7021 tttctataga gaatacaaat aagggaataa aagaggtaat aatcaaaatg ccaataatta
     7081 tgacatcgcc tatcttgaca ccagcttttc ttaaaaattt cattaacgat atctggctaa
     7141 acatattaga ctttttccat ggaaatggtg aaatttttcg gaaattatct gcattaagag
     7201 aatcagttaa acaaccctca agttgttcct taatacattg ttgatccatc ttcataccaa
     7261 taaaaactag tttattaatg cgttcaccaa acaacggatg ccaggcttcc ttcaattcgg
     7321 gatttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
     7381 atgattcaat acttttatag ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
     7441 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
     7501 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
     7561 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
     7621 ccactgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
     7681 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
     7741 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
     7801 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
     7861 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
     7921 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
     7981 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
     8041 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
     8101 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
     8161 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
     8221 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
     8281 tttttcctga accaagatag ccagttaaga ttgtaatagg tatttttttc atagggaacc
     8341 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
     8401 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
     8461 tcgtcatctt actatactcg aacgagaaag aatctttctg cttcacgaag aaggattttc
     8521 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
     8581 aagaaacaag aaaaaaacta ttcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
     8641 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
     8701 ttatttgtcg attttcagtg gtcgccagag gaaatctcga atcgtttgaa gcatgaacat
     8761 atggactttt caattagttt tatcacgatc taacgtgcaa tttgcaatga tcttttcgat
     8821 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
     8881 acaagacata caaaaaatca tgtcgagtct cgtggaaaga tttgccttac tcattcgatc
     8941 catggccgtc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
     9001 gtagctggca aaactggtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
     9061 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
     9121 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
     9181 gaattctcca atcatttcgc agttacagaa gcattgaata atatgccctt ttattttcca
     9241 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
     9301 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
     9361 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
     9421 ttgataaagt gttgcgcttg atttgacaat tcaagacata ataaaaagca gatcaaatcc
     9481 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
     9541 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
     9601 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
     9661 tgtactccca tttaatctca tttgctttgc aaatcgataa cgccgataag catcaatatt
     9721 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa aattgaattt
     9781 taatgagcca tcatttcttg agcaatttca tgtttagaca atgaagctgg atagaaagta
     9841 ggccaattat gcaattcatt atagagtttt tcttgacttt ctccaccaaa gaaaatatgg
     9901 aaatgctctg ccttacttgg tgcaattcca tgatcactaa attgaatata tttaaaacga
     9961 ccagcacctg catcatcagt ttcaaaatta aaacgaacac cacggtttcc tttttcataa
    10021 ttcaaaattt tgtatccaac atatttgtat gtgtattgat gatgttcacc gttgactaca
    10081 aaatcaatgg tgttgtcttt aatgttgata gtatcaatat ctgtcttata gccagtagta
    10141 taataatctt tgtactcggc agctgtcatg tctttattga tttttgcttt gtaatcgaaa
    10201 acttcatcca aaattccatc ttttaacaac ggataaacag attgccattc gcctgtataa
    10261 tcactcaatt cgcgatcctt cacatcggca tctttaaagt acccattagc aactgtcttt
    10321 tcatccttcg cttctttttc tggaactacc tcttcaccag caaccatagt tgttttttct
    10381 aacgctttta gattgtcttc cattactgaa acataatctt caccattatc catttgttct
    10441 tttgtaagac tttcaagagg attcagtact tccaatttta tcccagcttc gttggccaaa
    10501 gtttttgcaa ttttatcatt agcattcttt tcaaagtaaa tataattgat cttatttttt
    10561 ttaacatact cttttaattc agctaatcga ccagaagatg gctcttcttc aggacttagt
    10621 ccagcaatag gaacttgttt caatccataa tccaaagcta aatatccaaa ggctgcgtgt
    10681 tgcgtcacaa aacttttttg tttcgcttct ttaagactag tggtatagtc agcatccaac
    10741 cgtttcagtt tagtcaaata cttttcagca tttgtctcaa atacttttgc ttttttcgga
    10801 tacaatttaa ctaactgatc cttgatattt gaaacttcct taattgccat tttgggtgaa
    10861 acccacgtat gaggatctag ttcatgatgg tgatcttctt ctccgtgatc atgatcttct
    10921 tcttcactac ctggcaataa aatcatgtct tttgttcctt ctactacatt aggcccagct
    10981 ttcttccaac tttctttagc ttttggtacc catgattcca tgttttcgtt atgatataca
    11041 aaaacatcag catcatgagc ttttgccata tccttagctg agggctcata gtcatgaggt
    11101 tctgatcccg ctggaaccat taaatccacg ttcgcttcat cgccgacgat gtttttggtg
    11161 aaatcataca ttggatagaa tgttgttaca atttctaatt ttccatcttt atcattcgat
    11221 acttttgcat cattagtgct ggagcaagct cccaataatc ctagagctgc tatcccaata
    11281 agtcctacac tgattttctt cattcttttt ccttccttaa ttatgctaat ttcttcattt
    11341 tatttcgttt atgttctttg ataattttta atgccctttt tctagtttta atattcgggc
    11401 ttttaagtcg tcgatatgca ctagatatat ccgttttctc cattagaaat tacccccaat
    11461 cactacttat cattatttgc tttccgccag taatttatca aaactctgtt tgatcctttc
    11521 ttcatccaac atttttccga ttagaataat agtggtttgg tctttttgtc gagtggtgta
    11581 ttgaaaatta acctgttcgt ttacctcttg catggcaact ataaaatcct gctcttgtaa
    11641 agcaatcaat cctttaaaac gatacaggct cccttggttg gttaaaatca gccagtcaat
    11701 ccattggagt aaaaaatctt tttttatgtc ttgatctgaa gttaagagaa ttgatttaaa
    11761 ctcatgtact tgatggtgtt gatgatagta tttgccatta tagtgatttt ctgatgaatc
    11821 actttcaaaa actaagggat gattaaattt tttcaaatta taaaaatcct ttttttgaat
    11881 cgtttcacta tgtgtgaaca ttcgaatatc ggataaaggg ttaatacttt tgatttctct
    11941 ctgtaatttt tttagtgcag ataaattcaa gttttgtttt ctagacacaa aaatgcgatc
    12001 tgccatgaca agttgcttaa gggcttgtgg ttctctttca ataagttcaa aactgtcact
    12061 atcaataaca gtcaataaac tatcgatata tactcttcct cttagttgag gcgctgttaa
    12121 aagtgtttga atgattggtt ggggatctgc tatacctgta gtttcaatga tgatttgtga
    12181 aattggttgt tgatgttctt ctattgtttc cagtaaagaa atcaatattg ctaataaatc
    12241 actgcgaaga ctgcaacaca tacatccatt atttagttgt aacacccgtt cctcgctatg
    12301 aactaataat ttgtgatcaa tcccaacttc accaaactca ttttcaatta taataatttc
    12361 ttccctgggg tagggtgaga cttgcaaggc ttgattgatt agcgttgttt ttccagcccc
    12421 taaaaaccca gaaacgattg taactggtat gcccattttg tcaccttttt accacttagc
    12481 tatttcactt ctttaaaaat tgcccgtctg cgcaattttg gcgaatactt ttttaattct
    12541 aaccgttcag ggttattccg tttatttttg ctggtgagat acagacgttc tccagtttcg
    12601 acacattcca aaataatatt ttgacgcata aatcttcctc cttcaatact tatcgatctt
    12661 caagatatgc ttgaatttgt tgtgcatctt caaaagttaa ctcgccagat tccaattgtg
    12721 aaactaaatt ttctttcata tcaacaggta tctcccaata accatcgata cattgaaata
    12781 actcctcgtc atactcttca aaaattggat agattcttaa aaaatcatca aatgataagc
    12841 cttggtcctc atagtaatct ttgactaatc cattttcaat tgcctgttgg gtcggtaaac
    12901 ccgtttcagt aataattcct ctctctacca tcgaacgata aaaagtgcat ttatctagcg
    12961 attgctgggt cgtttcaaga taatacttta atccttcttc aactaaaggt gggtaaataa
    13021 tttccatttt gattccctcc taaaagttat atattaaact attttgaagc tcctttaatt
    13081 actttctttc cattatagta cccttttaaa gatacatgat ggctacgtct ataatcacca
    13141 ttcgcttcgt caaatgaaat ttctggtttt actacagttt gatgagttct tcttaaccgt
    13201 ttcttcgcct tagatgtttt tcttgctggt actgccatga tatttcctcc ttttaccaac
    13261 ttgctttttt tactccagga atcaaccctt gatgggcaag ttctctaaac ttaatacggg
    13321 acataccgaa ctttcgcata taccctcttg gacgaccatc cgtctgatca cgaagcctca
    13381 gacgattcgg atttgaatct cttggcaatt tagcgagagc ggtgcgatct cctgcggctt
    13441 ttaattcctg acgtttatct gcatactttt caatcatcgc catttgtttc tttgctttag
    13501 caattttcga cttttttgcc atataccttt atactccttt tattttgatt tagacacctc
    13561 aaatcgtaat cgttacgttt tgacactgat actttaccaa caagagttgc tcttgtcaac
    13621 aataaataac atgaaataaa actcatatga atagataact atttgaaaac gaatttatcg
    13681 gtacatagag ataatcaaat catttaaaag aatatgcagt ttaggctctg aaaaataaga
    13741 attcactttt attagtccaa tcaaacacaa ataccgtttt aagtagcttt tcctctactt
    13801 aaaacggcaa tatgaaagaa actataactt tttattcaat cttttatgtt taactggttt
    13861 atcgccaatt ttttaaaact ttgattattc cttatattat aagaatagac attaagtgaa
    13921 ctaattcaat catactgatt ctttcgtgta ttcaaaatta gatgctgttt aataaaatta
    13981 ttctttttga aaaagaatta taactatatc ccaaaaattg taggttaatt taaagcctat
    14041 ttcatcatcg tgattgagct tctttttcat agacgaattt ctcagatagt ttagttttct
    14101 ttatgagatt tttgtatatt tctgaccttc gatacaactc attatgagta ccttgatcaa
    14161 ctagttttcc ttgatccatc actacaattt tatttacctt ttcaatagac ttcaagcgat
    14221 gcgatataat tagtactgtc ttatcttgta ttaaacgatt taaactttcc tgaatacgtt
    14281 tttcattttc cgcatctaaa ctggcagtaa tttcatctaa aattaaaatt ggcgcatttt
    14341 tcaaaaaagc ccgtgctatg gataggcgtt gtcgctctcc tccagaaagt gaacttccgt
    14401 tttctccgac caatgtatga taaccgtcag gtagtttttc aataaagtct tcgcagttag
    14461 ctaaacgagc tgcttttttc acttcctcat ctgacgcttg actatttcca atacgtatat
    14521 tttccaaaat acttgtatta aacaaagtta cctcttgaaa aacaatagcg attttgctaa
    14581 acaaagaagc tggagataca cgtttaatat catacccatc aattaaaata cagccttcat
    14641 cataatcata cagtctagac actaatttca agatactagt tttcccggaa ccactagcac
    14701 ctactaacgc agtcacttct ccttgtttag ccgtaaaaga gatatgatct aaaattgggg
    14761 tattgttatc atatgagaaa gagacatctc gcaactcaat gtcaaaagat ttcagaggac
    14821 tatctgatcc ctcttggata ctggtttcct tcatagctct aattcgctgt attttaggag
    14881 ctaaataaaa tatttcaagc actgcttctt tcatagaatc gaaggaatcc tttattttta
    14941 ttgcggctag taagtaacca acgacgtaga gtatagtcac ttcacccgtt aacagtaagt
    15001 gaacacctac tagaatgact actgctaaac taacatatga gaaaatagag gataaggcca
    15061 tgactgaaaa agtacttaat tctaccttta aatgaatcct ttcactctct tccatttttt
    15121 tgaaaagtct gtcttgaact tttttagata gattaaagct attaatctct tgctgcaatt
    15181 ctatagtttc ttgaaattct tccgagtttt ctctcaaagt atcgtaatat ttagtattgg
    15241 ctttcgtttg ggatttcttt gataacaaga ttaagacaaa actaaataac gttggcaaaa
    15301 taacagctaa tcccattttg acattaccaa ccaaaagcat cactgaaata aaagggaaaa
    15361 acagagccat accgccggct ttaggtattg catgactcat cgcatgctca ataccttcaa
    15421 cgtcagacat gatagtttga gataaatctg ataaattatg ttttgaaaaa taggataatg
    15481 gtaaatttga caaatcgtct gcaatttgca ctcttaaatg cgcactttct ttataagtac
    15541 tattatataa gttttcatac tccctatcta acaaccaata catgaaaagc aaagtaacaa
    15601 acgatacggc aaaataaagc caacggggct ttgtattttc taaaactaat tcgtctatca
    15661 gcatcattat aatgaatgct ggtaccatat taatgcagta tacaaaaaaa ctagaaatag
    15721 aagctttagt taaagcttct gcgccctgat cacttaaagc aaatttgttt ttataaaaac
    15781 ttttcattgt caagcctcca atcatttgca ttctcataat tagtgaccaa ttgtttatac
    15841 acttgatgtt tagccattaa ttcattatga tttccacgtt ctactatttt cccttctgac
    15901 aagacaagaa tttcatctac agatttaatg ctggataatc gatgagctat cataataact
    15961 gttttttctt ttatcagatg ttgaaaagcc ttttgtagtt catactcatt atctggatca
    16021 atagatgcac tggcttcatc cataataaca atctttgcat cttttaaaat tgctctggca
    16081 atagctatac gttgtttttc tcctcctgac agataaactc ctttactacc aattaaggta
    16141 tgctctcttt cgggaaattt ttctaaaatc gattcgcaac cggctaatct tagcgcgtca
    16201 aatactttac ttgctggcgc ttgaggattt gctatagaaa cgttatcgta aatactctga
    16261 ttgaatagtt tcgtatcttg aaagacaaaa gcaattgtgt taataattgt gtcttttgaa
    16321 tagtgattta aaggcttacc accaatttta atctgtccct tatccacatt gtagaaacct
    16381 gaaattagtt tagctatcgt actctttccg cttcctgatt ttcctactaa tgcataaatt
    16441 cttttttgtt ctaaaactaa gttgaaattt tctaaaacac actcttcttt gtatgaaaag
    16501 ctgacatttt caaatgcaat gtcacaattt ttaatctgtg tctcgttccc atattttagt
    16561 tggtcttgct tcatttctaa ataaagggag tctagtgttt cgactgcata tcttgcttca
    16621 aacaagtgca tacttacata cattattctc atgaaagaaa caaaaataat tccacttaaa
    16681 aaaaacaaca tcaacaagtc aacagctaat atcttgggag tggtaagaga agttataaaa
    16741 aaggttatag gaactatcaa aatgcaaact atgccaaaaa atagccattg aaaaagaaca
    16801 aaaggtgttt tcccactcaa agaatactta tatgcaaact tagcataatc gttaattgct
    16861 ttattcaagg ctttaaatga tgttacttta gcaccaaata tctttataac ttgaattccg
    16921 cggatatatt ctaccgtttc agagcttaac acatctaacg attcttgata tttttgaata
    16981 aaatttgtat tctctgtcat tttctttaac aagaatacac caattactaa catggcgatt
    17041 agaaccaatc caattttaaa gttaatgaaa aagcctaagg caactgataa aacaggtgtt
    17101 actatggctt gagcactatc tggaatcaag tgagcaattg ccatatgtgt tttagccgcg
    17161 ttgtcatcaa ttgtctttcg aatatatccc gaagaattta aatcaaaaaa acgaaaactt
    17221 gcttctgtta aaccgctaat tccctttttt ctcaaattag tctctaagcg aaacccaagg
    17281 atatgagaaa ataagccaga aaaaatataa aataaagctc ctaaagttaa ccaagcaaca
    17341 gtttgaaccg cataactctt agctaaatat tcatctccta caataattag agactgaaga
    17401 aatttgtaaa tactgtaata tccatagact gttaatacga cagaaaaatc agaaaataaa
    17461 gtggctaacc atccgtagta tttcatttta gggacataac taaataattt tttgtatact
    17521 ttcatttttt cctcccccgc attcaatttc ttctcttatt cgtttacaac tgttaatgct
    17581 ttccgtaata gcgtaaatta gagatgtaca aacagataaa aggtaaacta cgttctattt
    17641 tttgtatttt tttaagactt ttcttccaat caatacacca atcatagata aacttgctac
    17701 aactaacact gaaatgattc cccatatacc taccgcatag tggatcattg catccattgt
    17761 tgcagcagat tgtcctttat ctatccaatc ttgacgaaaa cgatctgtaa agaaccatat
    17821 aggaatccac tgtccggcag cactgcctaa ttgcattaga gcccaagacg caacttgagg
    17881 aattgctcga tcatatccaa atacagatag aataatatca gctaagatcg ccatactaat
    17941 cgaactgata aaccaaggta agtacgcccc gcccattaac gtaaaaaata acaataaaac
    18001 aattgtgtaa atagtaaaaa ttccttttct agggtagtta tagctaatat aaacaaatat
    18061 gattccagat aataatccaa aaatcccggg ggatatgctg tgaccaaacg ccccaccaat
    18121 actactaacc attattgaaa aaaagtaaat tactagggaa ataactgtag ctaaaccaat
    18181 aaaaatataa tcttttgttt tcatatatat tctcctcaat tctatttcgt tatgtcatta
    18241 aaaatctgtt ctatcaaagt tgaatcttct actctaagtt ttatatcttt ttttattcca
    18301 ccatttttta aataaataat tctattgcat gttttataaa gaaattccgg atcatgagta
    18361 gctataacta ctgcaccctt ttcttttaag tctttaataa ggtcagcaat cctttccata
    18421 ttaatataat ccaacccact tgtaggttca tcaaatagaa ataaattagt ttttgacaat
    18481 gaagctatag aaaccaataa tctttgtttt tctccaccgg ataaatcaaa cggtaattga
    18541 tctttcattt tataaagttc catttttttt aaaatttttt cttgctgatc tttactaact
    18601 atttcattcc ccagggctaa ctcgctcctc actgattctg tgaaaaattg gtaatccatt
    18661 tcttgcatta ctaaaaacgg cgatgacaaa ttttttttat tttcgattat ctttcctttg
    18721 gtagggcgaa taatcttcat gagtattctt agtaaggttg ttttccccac accgtttttc
    18781 cctaccaaac caataacatc tccaactttg acatcaaaat ttatgtcttt tagaatattt
    18841 tcataagtaa tttcttcaac ttttaataca tctgcactta ccttttcgat atagggaact
    18901 tcaatcgaac tattaaaaat gtcaaatttc cttaatgcgt tattgttttc agtttttaac
    18961 aactgaatag ttgtagtttt tacagttcta tttttaacaa atagaacttg atcaattaat
    19021 tctttcaaat agtaaaaacg atgttcagct ataacaatag taaatccttt attttttaaa
    19081 tcacaaagta agtcagcaag tttcttagtc gctttgaagt ccaaatttga agacggttca
    19141 tccaatataa ttaatttaga gtttagcgat aaactacatc caatagaaat tttctgccgt
    19201 tcaccacttg atagcgaaaa aatgttttta tctaatatat ttgaaagatc taataattca
    19261 gctaattcat tgattctttt atccatatgc tcttttgtaa atccaaagtt ttccatcgaa
    19321 aatactaact cactcgttgt atttgttgta aagaattgtc ctctaggatc ttgacttacg
    19381 tagccaatat tttttgatat actttcttgt gttaaggatt gtagcgagtt attttcaaat
    19441 aaaatttccc caaccaattt tccgtcataa agtcttggaa taagtccatt cattaacttt
    19501 aatagtgtgg atttcccact cccagaagaa ccagtaatca atgtaagact gccttttttt
    19561 attgaaaaat taaggtcaac aagcgcttgt tccttaacat ccttatatga aaaagaaaca
    19621 ttgttaaatt caaacaattc tttcacctca aatcaaaata cttaagaaaa aaatagtaac
    19681 ggaaaacagg atgatatagt ctaataagct catgtttgtt ttatagtaag aacttctttt
    19741 cacaggagat tctatcccct ttgttattgc attagcggtc atttcttcag caatcatagt
    19801 tgcacgtata agaacgggaa ctaacagaaa ttccaaatat tgcagaggct gaaaaaaaga
    19861 caagcgaatg tttctcattt ttaaagattc tttaatcatt cttatttcag aacgataagt
    19921 cggaaagaat ctgatcacta ctgtaatact taacattatt tttttcggta aatgtatttt
    19981 ttctaaagag gataataatt cattgctagt atagacacta accaacaacc atgagatcat
    20041 tacgaccggc aacattcgaa atacaatata taaggatgtc gcaaaaaata tagtaaaaaa
    20101 ctctatcttg atagcatcaa taattttcat tactaaaaac agaactgaat aaatcaagat
    20161 gaaataaata catgtcttta ttttacgaaa catcaatact aaaactgtag caataatgaa
    20221 acaccccact tgaaatatat ttccctttcc taaaaaaata atgaccggaa aaaaaatatt
    20281 taaagtaatc aaggttaacg gattgatttt tgacactctt tcacctccaa aaaataagat
    20341 cgcactgtta tcttaagctg ataaaaatgc accgttattc agataacagt gcgatcttat
    20401 caaaaagcat aactgagaac aattctcaat gcaagctttt tttaattaac tcagtaattc
    20461 aatccaccca ggaacagaaa attgatacaa tcttctggtt aatagcatag tcttttcttt
    20521 tgaatagcta tgcttcaata tatcatagaa tgtagcgtag aatgagtaaa tgtagaagtg
    20581 gatttcttct tcattaaaga ctaaattttg attgatcatt ccgatagtct ttaacttatc
    20641 tagacaacag actgtctttt tcgtcacaaa tgatgtaatt ttttcaacaa tatcttgata
    20701 tttggttcca gctgattgga ataaaatcaa atcgaatata cgtttattct caaaaatata
    20761 attaataaat ggatctaatt cattgaagtt ctctctccaa cttttctcta tatctatatt
    20821 ttctaagttt aagaggtatt tggtaaactc ttcattatac atattaataa gcgcattaat
    20881 atgcggctga ataatttctt caaataacgc ttccttagaa gtaaaatgtt tataaaaagc
    20941 acccgtagtt acgcctgcgg tcaggcacag ttgccttatc ttagtttgct gaaatccttc
    21001 tttttcaaaa tggcttagtc cactttctat taacttttgg tgagttataa tataatctct
    21061 ggtttctatg ggtacttcct cctaataaga tgaattaact ttattatctt acacaggact
    21121 tgaagtttca atcgttaacg tttattactg aactcattcc ttagagctaa actaatgaga
    21181 aagagcagaa taactgatac aaaaagcaat cctacaagaa ttaatagact catctaaatc
    21241 attcaccttt tctaaaataa tccgagaaag atttaaaaaa attatatcca gctattagga
    21301 taagtcctat cataatcact ccaatagcca ttttcttatc ctccctaaaa ataaagtctt
    21361 ttacttaaaa ccttttttgt aatcgtcaat aaattttttc cctttatcag ttaattgaaa
    21421 tcctatatct aaatagtcct catatctaag tttagccagc atctcactta cagatgctgg
    21481 actaacactt agaacttttg ctaaatcatt attttttaat ttcttttttc tttttgataa
    21541 ttcctgaatt gctagtaaat aaattagtat agtagtcgtt ttaatttgta ccatacctac
    21601 cctccaaatt atttcgaaag gccttcagca attttatcca ggttccattt catcatcgca
    21661 tagtaactat caccatcttg tcctttttct gcaattgaat cagtaaaaat cgttgaatag
    21721 ataggaatat tggtatcttt tgatactgtt ttcattggtc tatcatccac actgctttct
    21781 acgaataagg agggaacttt tgttgtgcgt aatttttcaa ctaagtgttt tatttgatct
    21841 ggtgttcctt cttcttcagt gttgatttcc caaatgtaag cagaaggcac attatacgct
    21901 ttcgagaaat atttaaagca tccttcactt gtaacaatca tttttttatc attcggaatt
    21961 gaagcaaatt tagatttagc ttctttgtct agagaatcca atttttcaat atacttatct
    22021 agattttctt tatagaattt tttattatca ggatcttttt ccgctaactg tttttcaata
    22081 tttttagcgt aaataatacc gttttctaaa tttaaccaag catgaggatc ttccttccct
    22141 ttctcactct gaccctctaa gtaaataaca tctatgccat cacttgctgc aaaatagtct
    22201 ttgttttcct ctttgttcgc atttttaact aattttgtaa accaagcatt tcctccagtt
    22261 tccaagttaa caccgttata aaaaatcaaa tctgcttttg aagttttttg aacatcttca
    22321 ggcaaaggtt catattcgtg gggatctttc ccaataggta cgatactgtg taaatcaatt
    22381 ttatcttttg ctatattttc ggtaatatct gctaaaatcg aattagtaac tactactttt
    22441 aatttttcgt tcgaagccac tttatctttg tctttactat ttattgaaca tgccccgaat
    22501 ataaaaagag caatcaaaat ccccagactt cccagtactg ctttccattt tctcatcata
    22561 acgatctctc cttctttctt aaaaattttt gttttggtga gattagaaaa ctaattacaa
    22621 ataagaatgc cgctgttaaa acaatacttg atcctgctgc tatgttaaaa ctataaccaa
    22681 taaacaatcc aagcaatgat gaacttgctc cgactgttgc agaaataaat atcatagttt
    22741 tcaagctatt tgcatataaa tatgctgtag ctgctggtgt aattaacatt gcaacaatta
    22801 atatagttcc cacactttgc atagctgtta ctgctactaa agttaataga accatcaata
    22861 gataatgata aaaactgaca ttcatcccta ttgcttttgc cattaatgga tcaaaagaag
    22921 tgattaataa ttctttaaaa aatagaacta ctataaccaa cactaaaacc gaaacgccaa
    22981 ttgtaatcca cttatcaata tcttgtacag ctaaaatatt tccaaataaa atatgaaata
    23041 aatccgttga gctatttgca actcctataa ggataactcc tagtgctaaa aaagaactga
    23101 aagtaatacc aattgctgta tctcctttta ttacactatt gctttttata aaagtaataa
    23161 tgatagaagc taatagacca aatacaatcg caccaataaa aaaattaata cctaaaatat
    23221 aagaaattgc tactcctggc aaaacagcat gagaaatagc atcacccata agagacattc
    23281 ctcttaaaat aataaaacaa cctactgttc cagaaacaat ccctataact acagatgtaa
    23341 ttagagcatt ctgtaaaaag tgaaagtcat acagaccatt aataaaattt tgaagcatat
    23401 tattccccct ctccaataaa tatagtatct ccataggctt tttttaaatt ttcttcatta
    23461 aatacagatt ctacacttcc gtgagcaatt agatttcgat tcaaaagaat aatattatca
    23521 aaatacttct ttaccttgct taaatcatga tgcacaatta gcactgtttt tccctgatgt
    23581 ttcaattttt ttaacgtatc cataattatt cgttcactaa ctaagtctat ccctacaaat
    23641 ggttcatcta aaaatatgaa atccgcattt tgagcaagac atcttgctaa aagtacacgt
    23701 tgaaattgtc ctccagataa ttctcctatt tgatgattag aatattttcc catatcgacc
    23761 ttttccaaag cctttgaaac tctttgccat tctgcatttt taattctttg aaaaactttc
    23821 attccggcat atgttcccat agatacacat tcttttactt ttattggaaa agtaaaatca
    23881 atatcagctt tttgctctac atatgcaatc ttcaccagtt ttttattgat atcttcatta
    23941 ttaatggaga cctctccctg atgagggata atatttaaca ttgctttaag caatgtggat
    24001 tttccagcac catttggacc aataatacct gttaaagcac cttcttgtat ttttaaagaa
    24061 atctcgttca atgctaaaaa atcgttataa caaacattaa gctttttcac ttctaacata
    24121 actttctcct tctaaatgat aatgattatc acgatcatat ggtatacaaa aattatattt
    24181 tagtcaaccc taaattttat agtttagatt tttttctgtt gctgaagatt agaatgacaa
    24241 aactatttga aactacgcgt atagtaagta gctttcaaaa tatataaaaa aggagcgttc
    24301 tcaaatgaga acatgctcct aaaactactt tattggcgta tggaaaaatt atacttgaag
    24361 tggatagcgg gttgaataag ttgataagca tcaaaacatt tataaaaatt attcaagact
    24421 atgtctgttc catatacaaa tatgaaaatc agtaaactcc atttaacttt tttcgtagtg
    24481 tgtcttttta tacatgttta tcgttattaa tagtgaatag gaaaaaaact atttttgatc
    24541 attgacaatt aaatacaatt tttgaataac gatccctgct attcgagcta gaaactcaag
    24601 tacgccatga cctgattagc gacaaatact tagagatttc tttttgttct gggaaaacaa
    24661 aatgccatga caatagcagc aaataatgat acttccgtaa ggctcgccgt aaactgggga
    24721 gaggtgaaat tcctatgtgc ttacccaaag caattcaaaa atttcataac tactatttta
    24781 ggagatgatt ttatagaatc cagagtctac ctgaataaaa aacaaacctg tgcatttcta
    24841 ggaatcgata ataatactct agataagtgg attcgtatat ataatttccc agtaataaga
    24901 gttggtggtg tagttcgctt tgacgtagaa gatattaaag actttatgaa tacatttaaa
    24961 ataacttgaa attttcttct cgccgcatat actaaaatta gtgaaatata ctgccttact
    25021 ttttttaagg agtgaggatt ttgcctacaa agctttcaaa tgggaaatat aaaactaatc
    25081 tgagatatcc aaaaaggttt aaagaaataa caggaattgc atcagaaaag tatcaaaaaa
    25141 catttccaaa taggcaattg gcgattaaag ccgaaaatga tatgaagaag aaaatagaaa
    25201 aagttttgag agaggagaat gcaaactcat tagaattaaa aggaaaaata acgtttaaaa
    25261 aattttacga atctaaatgg cttcctagat atgaattagg tcaaacaatt agatcaaaca
    25321 ggcctcctag tgatataacc attagtaata caaaagatat atttcggttg catattttac
    25381 ctatgtttgg tgaatacgca atgaattatc taaatatcaa tactgagata atatcagatg
    25441 aattaaccaa aaaatcgaaa gaatatgcaa atataaaaat cataaaagga tatgttcgtt
    25501 ccatgttcga tattgcagaa atactaaatt atatcgaatt taatcgaact actaaaatta
    25561 ttcaaagtat cactgcacct aaaaaaaatg ctttagaaga aaaaagaata caagaaggta
    25621 agcaagcact atcatcaaaa gaacttacta attggataga agcagtaaat gatgatttta
    25681 ataatcattt acttactttt catgattaca cactttttat gattaccctg tatcttggtg
    25741 atagaaaaag tgagacttac gctttgcaat ggaaatatat tgattttgaa aaacaaacgg
    25801 tccgtcttaa acatacttta gataaatatc aaagaaaaaa gtttacaaaa ggtcgaaaag
    25861 ataccgtcat tcaagtacca gaagttgtaa tgacattgct aagtgaatgg aaatcggtac
    25921 aagctgatca attgttgaaa ttaaaaatta agcaaacgtt agatcagtat ctctttactt
    25981 atactaaacc atctggagaa gtaaattgtc ctgttcatgc cgattaccta aactatcgaa
    26041 tcaattcaat taaaagaagg catcctgact tagttcattt atctccacac aaactccgtc
    26101 atacttatgc aactatagct agacaaggtg gagcagatat gaatcaaatt tcaaatgctt
    26161 taacacactc agatatttct acaacaaaga tatatgtgaa cacaccagat atagttgata
    26221 aggctgtttt tgaagctttt cagagaggat tgaataagtg tgattgatat gtgttcttaa
    26281 atgtgttctt aaaaacaaaa gaagcacttt ccaaataatt gaaaagtgcc agaaacgttg
    26341 atatataaag gatattaacg ttttgagaat tgtgaagctt tacgtgcttt cttaagacct
    26401 ggttaaacaa acttttcatt tataatgttt tacagagata tatgtcgtat gaaattaatg
    26461 ttctcttgtt catgaagttt tacagaattg tatagggtta tctgttgtca ttacctcaaa
    26521 tcattaccac aacttggcga gttggctgat tgaagaagta ctctgtttta ctctatctta
    26581 ctctgcttta ctctatctta ctctgcttta ctctagctta ctctgcttta ctctagctta
    26641 ctctatctta ctctatctta ctctgcttta ctctatctta ctctgcttta ctctagctta
    26701 ctctgcttta ctctatctta cctgctttac tctatcttac ctgctttact ctatcttact
    26761 ctgctttact ctatcttact ctgctttact ctatcttact ctgctttact ctatcttact
    26821 ctatcttact ctgtcttact ctatcttact ctgtcttact ctatcttact ctgttttact
    26881 ctatttaaag aatagtattg agtcggatct ttggtactag taccatgcca ctgaattatt
    26941 tttttcctta acatttcctt taatacctta cggctatatc cgaccccttt ttttaatact
    27001 tctgaagctt cttttaccga aattttttcg ttattaaata aatgtgaaac aatcatcttc
    27061 tcagaagtag acaaagagtc tacttcaaat tctccaagat aatcatctag tctgtctctc
    27121 tctcttaaat gtctagaggt tatactattt tctaagacta ataaaaccga attattattt
    27181 ggctcactat atttaggttc atttaaaaat agtaattgca tttcgtcata tattcgattc
    27241 acaccttcat taagttcctt aacccatccg aattcagata atgtcctagc gattctggga
    27301 ttcctagcat acctagttcg gcgcatattt tgtaaagtga ctatattagg taaagctccc
    27361 gggctaaaaa tttctaacct atcatcatac atattaattc taacgtaatc ccctttataa
    27421 gaatagtctc tatgcgttaa agcattgact ataccttcaa accatgcaaa ttcaggatat
    27481 tcaggtatga tactaaactt tccatcatca tttaaatact gaaattctct tagttgcgtt
    27541 tttacatccc tagttataga ttcgattagc tttggaattg caccttcata gtcaaattct
    27601 ttaactatat ttaatctccg tccagtttca ttacgcttac catcatatct caaaaaacga
    27661 attctagaat taggtaaggc tagaaatgta ttcttaccaa atagaagcat gccagcattt
    27721 gtcaagtgac catttctcat taaccctctt ccagtgagta tggtttctgt ggatatcgct
    27781 tcagcttttt ttaatttttt atatgaatcc atgagagatt catcaatatc atcaagagta
    27841 ctgtctaaaa tttctatatc ttcaaacatt ctctgtcctt tgtcgtattc tagtttggat
    27901 atttggtcat gagtttgatg aacactttta tccccaattc tcaagaaaca atcaccgttc
    27961 gaattaaaaa tcacatggct tatgctaggt tcaacgtcta taatgaataa tatatcgtct
    28021 tctcctctag cattcttaat actcttcatt tcttttttaa aagttggatt gggttttgtc
    28081 attgaattta tagctagtac atattcatct ggatcgatcg caccttgaaa tttaaaccca
    28141 gaaatagtcc catcatcttc tataccgatt accagcttac ctccatcggc atttgcaaac
    28201 gctactatgt gttttataat atctctaggc ttaatccgtg cactttttct atcaaaatac
    28261 tgatcttctt tttcacttat aaacttttga atctcataat ccatttaaaa tttcccttct
    28321 taaatttttt tattatagag ccgtatattc aatttccaca aaaaaataat ctaaaacaaa
    28381 acagacacct tcattttgat atgttctccc acatatgaat cggtcgctat acagcattac
    28441 atatagtaat tattcatact gcgaaataaa tagctccaaa tctttagctg gcgtagttaa
    28501 gcttaaattc gaaatgaaag tttcattgac tattccactt tcatcaaatc ccttcttcaa
    28561 ccaatcagag ttccacaacg taaatccttt aggattagaa actttcttac ataattttgc
    28621 actataggat ttctctcttg aatgaattaa agaaagtctt tgtaaccaaa tttcaactat
    28681 atccgtatta ggagtattaa caaattttct taagatttta tccaagtata agttgatttc
    28741 ttctacagca ataaactcaa aaagcttacc taaaatcaca atacaagcct ccaaagttct
    28801 aggattcttt tgcattatat taacaagaat actaatcaat tggtagatat catctggtct
    28861 tttgtttaaa gtagaaactc tatgtgtata gacttcactt agcgctttac ttaaactccc
    28921 gcaatttgga tatttgtctc ctaaaagctt tacctgtagc aaatgctttt gaaggctaag
    28981 cttaaacttc cacttattat tacttttctc tgtaaaactt gcatgtttaa gatcccagta
    29041 aattttatca ggcttaattg catctaaaat tatattatcc gataagaatg ttttatttga
    29101 atttagcttc aaatttagat ccgataatac ttcagataac aatctgataa tcacttcagc
    29161 ttgatctttt cgaaccgaaa aaattctata atcatctctg taacgaagta ttttgaactc
    29221 tttaatctct gttttttcta tcttgttcag taacatttta tcagcatacc caagtactat
    29281 ttcagctaca aaatccatca atacatttcc ttgaggtata ccgttcgttt gtccattttg
    29341 taaatatcgt attttagaat ctattaagtt tccaacgcct tgagtatctt ttctatgtgt
    29401 cttagcccat tcttttgaat gtactgccca cgggatagta tgtgtgtaca ttgagctata
    29461 acaatcggta atatctgaat gaatgcagta gtcatactcc aaagcataac taatctgtgc
    29521 ttgttcaagg ttctcccacc aatttaaaat agtttccgca gtatcgctct ttgaagaaat
    29581 agattccaca ggaagtgata tacattcaat tcgcttgtcg gcttggaatt cttcaaactt
    29641 atttttgatg tgattccaat tatttttctg tgtaatcccg tttactaagt ctacatatac
    29701 taatggatgt aatatttgaa ggggtctcca agcataatta ccatctttat tagctaatat
    29761 tcgatgatta acatcaactg cctcagagag cgatctctta tgtctaacta gttcagtaaa
    29821 tgatttgttt tttaataaat ccactgcttt ctcaatgcct actgataaat caatataatt
    29881 gggcaacgat gtactaaaaa aacttgatgt ttttaaaaag aattgctttg cttcttgatg
    29941 attcatctct aaaatacttt ttctagtcct agtcaaattc aaaatctcct agatcaatta
    30001 agttgtaatg taagaggata ccctaacgtt acatatctca ttcattatta taccagtatt
    30061 tcttcatgac acataagggt gtaacataat aattttaaac gaaatgacta caagtagtca
    30121 ttgaagtaag tcttcataag atacctgtag gatatcccta attgctctca attgatctaa
    30181 cttaatgtgt tgccggccac cttcaatttt aaccaatgtt tccctagtta tagcaatttt
    30241 atgaagctgt aggtctctaa tcagctcggt ttgaccaatt cctttttcta atcggattcg
    30301 tctaatattg ctaccgatta cattttcttt atcaataatt ttttcctctt tcaagaatag
    30361 cacacctttt ggactaaaat tagtcctttt tcttattaat cttaaagatt cggtatgcta
    30421 caatgggact agtattagtc cacattcaat tttaaggagg aatttttttg aagaaatttg
    30481 caatcattct aacctgcgct ttactcatcg gaactataag cgggtgtacc acttctgaaa
    30541 caagttctac aagtacggaa actagtacaa caacctcaga aaagaattac ccaatacatt
    30601 tttttccggt tccagatgga tttgaagctt attatcatga taaaaaacta gatgtccctt
    30661 tatcagaaac tgaatctact gaaaagattt tgccaattga aattgaaaga aatcaagacg
    30721 atataaaact aaaagctgat cttcccttac tgaacagcac acaaattgat agacatgaaa
    30781 atattaaagt taatattgaa aaaggagcgt tagcaaaact ttatactgaa aaagttgaac
    30841 aattttttaa gtctggtgcc aataaagact tttcaaaaat aagcgattat tcggagaact
    30901 tttttaatga aacccaagat gaaatcatga actcaacttt tatggctgaa gatatgtaca
    30961 atatgacatt aaaaaaaata aaagcttacg accatccgtt aaatctgaca ctaaataatg
    31021 gactgctttc ttttgtatta gcaggttacg ttgactatga atattcacca gattatttgg
    31081 agaaacctct tcaacacgag aacaatgata ttaattttag atttgtctac gagtcaaaaa
    31141 gtaaaacatg gttagttgat caattaagca cgataaacac aagcttccat gaattaccta
    31201 aacctgaaaa tgaagttgag atggtcatta aaatcttcta aaaaagaagc gttgaaggag
    31261 aaatattcct ttcaacgctc ttttttatat gcttagaaac ataaataaat tgtatacttt
    31321 ctttttagcc cctattactt ttcacgaaaa atatcttttt ttcgacgcta gcgtttctct
    31381 acttctaata ctgtacacag tttttgtatt attgaaaaat tactcattat ttagcattaa
    31441 tccacatcgt tttatcaatc gaccttcata ctaaactact ttaaagtcat cttccttctc
    31501 gtttttcatt aaatcagaca cataagccca tgtacccgtt cgttgtaaat aaagttcttc
    31561 ttgtaacaac tcccattttc tcttagaaat cataatgacg ccatcgttca atccattttt
    31621 agaatcccta gtaatttcta tttcagaatt tgaatgaact acttcttgca acactttacc
    31681 tatattttct ttgaagtttg ttggagtaat agtatccaaa atgaacacct ctcttctcta
    31741 tacctctatt atgaagcgcc catcaaataa agcaagcgtt gaggaataat tctatcaaca
    31801 cttgctttat taagctttca ttttgtagtt tgactaaaac caataatctt atttctaaac
    31861 tctcgaaaaa cttcttgtgg ctgataatag tctgcatcta tttcaaatgt ttctgagaat
    31921 aattcattga atttttctac tgaaataatg attttaccat tcttctctcg actgttttct
    31981 attatttctg cttctaattc aaataaatct agtgacgaat taaaatcata aatcctgtca
    32041 tattgaacaa aaaaatcaag aaaaagttgc tcaaactctt tcttatttat cactagtgtt
    32101 tcaagcagat caactttatt ttcttcagtc attcttccaa tttcctcact ttcgttttca
    32161 aaaatcacaa aaatgatatt aacttaaaag ccactaacaa aataagactt acaaattaaa
    32221 gggtaatcca acaaaataac cattcgctct acgtactacg atttggtagt cctgcctttc
    32281 aatcggtaat tcataatagt aatttactgt ttctgattta ccactttcaa tatactcagg
    32341 attatccaat atcatagcat actcataaag ctcttcacca tccttatttt caatcgacca
    32401 ttgttgcgga cgtatcggat tttctgtatc atttttcatt gtataggtca cttgtaatac
    32461 acgatcatgc tgtgcaaatt catttctttt ttcggtcagt tcaatatttt taaatgttag
    32521 ttcaacccca tctgcctgat aagtttcacc tatttttaaa tcttttgtta caatttttat
    32581 tggcttttct tctggaaaat acctggcttt aattgttaga taacttccaa aaagaatcaa
    32641 tcctagtagc acaaaaaaaa ttcctttaac gagccactga aacgggaagt aaactttaaa
    32701 catctttttt ctcctccgtt ttgtatttgg tttttagaga acacgataac ttttgatcaa
    32761 taccatccaa ctttttcatt atacttgatt ctagttctga aattgtttgt tcaagtttaa
    32821 tgctttcagg atcactaaat tttttatttg attgactagc caacattggt aaatttgaaa
    32881 ccatcacacg gaacatattt gctttcgttc caagagttcc tttattcttc tcataaaagc
    32941 tgtcaaacaa tttttttgtt tcctttgaac aatatacttt aatatacgga tcagacattc
    33001 ttttccctct ccctgtttac ttaaaaatcc atatcatatt gattttgttg tttttgataa
    33061 tcaattcctc ttgctgtttc ttcatactct ctccgagctt tttcaatcgt accatcatca
    33121 attgcacgat taaataaata aagaacacgt tttgtttctt gaatataacg cttcttaaaa
    33181 ttacgtttta aagcgggttc agtatcttga atgttaaatt ggtcataatc agttgataaa
    33241 ctctctgcga tatcataaac aactttttta tacaccaaat ttacacattt cttcttatat
    33301 tttaaaggtt cctcttccac tgcaaatcca aagaattggt ttttattctc accaaaaaca
    33361 tccaataaat tttctattct gtcctctatt tcaaatttat atttatcata aaattcttca
    33421 taatcttttg atgatctaag aaatggtata ttctcattat ctaattcaaa gcgttgcgct
    33481 cgttcttgcc aattaaatct actatccgct ctaccattta acgatttacc aagatgtcga
    33541 atagcaattt cagtgagtac ctctttagat tgaatttgct ccgctttttt attttctgtg
    33601 aacaaatcat caagataatt catatcatag ttttgcccta aacgctttcc gccaattttt
    33661 aagattaact cgccttcaga atctaagagt ttgtacccaa tacgctgatt tttggcaaac
    33721 cggtaagtct caatagaatg gtttttcttc aattccgcat gaaaatcatc ataatttttc
    33781 gcatactgag caacttcaga aacagctagt tttatttttt ctcgatttga aatcttattt
    33841 tcagttctaa attcacgttc tttccaattt tcacgatctg caactaaatg attatactta
    33901 tacatatcaa gtgggttaat tccattatca ataagtatat tatcattcca agcctgcaaa
    33961 actcgaatat cattctttcg aatatccatt ttctttcctg ttagctgatc gtttggcgaa
    34021 ataccaaagt gattgtgaac atgccctttg tctgtgtgtg tgacaaccaa aattgactgg
    34081 ttaggaaaca ttttttctgc ccacttaaca cccaactcat gtgctttttc agcggaaata
    34141 tcttctagtg gatcaaagct ttgtgtaaaa tgccaaagct ttattttccc tttatcacca
    34201 aaaatttcat tggttcgttt aaattcctca atagcattta aatcattcga tacgccaatt
    34261 cctgtcacga gttcagaatc ttcttgttta tttaacatat atgaaattgt attatgaata
    34321 ctcctacttt ttgaagcaat ttttataatc gagcccataa cttattcaac tctttttcca
    34381 agcgattcaa tggatcgctt attgatttta tttgtatcat taagtcattt ttttcagcat
    34441 atagccgctt taatcgctct tgcttagttg taaaagataa gtaaacactc tgatgttctt
    34501 ctttttgtat ctcggtatct tttttattta actgaacacg caaataattt gctgttttca
    34561 ctaattgatt caaatttctt cctattgcta gtaaatgaaa attaatttct ttatattgtc
    34621 gatcggtata ttttagactt ttccctgcgt tgtctactgc gattttcttc acgtacattg
    34681 gaacagataa accaaaaatg tctgctgttt tttctagctc ttggtactga taatcgtcta
    34741 ctcgaaactt tatcggccta ttttgtcgtc gactatcttc attacgttta tatcgctttc
    34801 gcctttcttc taatggtagt ttactgacat caattgccat gcgcacttct ccttttcaat
    34861 attattttta agttcaaaag aagcaagcga ggggaaaggg aacccttccc cgcttgtcga
    34921 gggagtaaac tccctacgag caccctcatg ctccgcattt tatcgagatt agatagccga
    34981 taaatcagct acctaacact ttcttcttgc gcctcttctc gatagaaaat tcgatacgct
    35041 gtctctcctt ttcttctcaa aaattgttgg aatttcgttt ccatcaattg atcgcttgca
    35101 agaaattcgt gtactagggt aaattcgcta ttcgcgaaat ttaccgcctt ttgccatttt
    35161 tcttgagtac ctttttgatt aatttcaaaa gtttcttcaa actcttttac tgatgaaatt
    35221 cctgtttttt catagacata ctttcccagt tcgggataaa gttttctctc caactcggcg
    35281 agttcttttt tcaaatctgc aattgacttt tgttttttcc ttgccatttt tcatgctcct
    35341 ttttgtatgt gactaagttc attcataagc tcatttttca tcattaattc ttcttgaatc
    35401 atcagttcaa tataatttgt gaccgtgatt ttttcatttg ttgctttctt tactgattca
    35461 cataattcgt caagttctaa gaaatcatgt gtactaatct gtagaattaa ttgcatgaca
    35521 atcacctctt tattttttaa atagactatc aaacagcgga tttggtttat cagaaatatc
    35581 ctgaaacagt ggattatttt cataagtaaa tcgttgacgt ttcttctcct tcacttcttg
    35641 ttctacaatc actttttcgt taggtctttc ttttcgttcc tcgacaatat ttattttttg
    35701 cgtcttatct ccctgacttg cttcagctct tgtttcacgt acttctaccg tttttggttg
    35761 atttggcgca ctactttgta cattttctcg tacgtctact gttcgatttc cactttgact
    35821 acttgtagta tcctgtaagt ttaatcgaac atctaccgtt cttgtttgac ctgtactgct
    35881 actttgcaca ttctctctga catccactgt tcgatttcca ctttgactac ttgtagtatt
    35941 atgcaagttt tctcgaacat ctactgagcg cctatcttga ctacttgtag aattttgtag
    36001 attttcttta accgattttt ctaatccggt atttgaattt ttagcttctt ggattctttc
    36061 tttggtcaac gcttcttttt cgtccatatt agctcctgta cgcccttcta cacgtttcct
    36121 taacatttcc tcacgattca ttgcttcagg cgtgtatttt gcttcctgtc gcttctgatt
    36181 aattaattct tcagcagact tagcttgacc gtgcatagca tttttacgtt cttcaatatc
    36241 ttgttgaact ttttgctgaa ttgcacttgc ataattagta tttgattcag caatattttt
    36301 cattgcttca cgcatacgtt cagaactaga cataattcta tcggcattct caatcttagc
    36361 cccatctttt ctatccgaaa gacgtattgg catagaatca gcatattttc cagtttcatc
    36421 ttctttgttt ttagctacta taggtttgct atttttatta atagcggaca cggtaccatc
    36481 atctaaacct tctttgaatt tattcttggt atcattagcc atatcacgca tactcttaaa
    36541 tggttttgtt gctctttcac tagccattgt agctccatcc gaagctaagc ctgataatcc
    36601 acgttcacga gcatacccaa gcgttttccc cgttttatta gctttttgag aaagtgattg
    36661 accaaagttg cgttcaggtt ttcgttcttc cccttccgtt tgatcgtttc caccactatt
    36721 tttcccacct ttagatcggt tcatgccacc tgttccttta cgaaacagca ttgcacccat
    36781 tccaaaagca gaagcaagtt gcccatagcc ttctttgagt ccaatatcca caccaaagta
    36841 acgcatgact gttccactgc ctttgattaa aacaaacaca gcacagatat aagcaattgt
    36901 ttttataaaa atatttgttg agataccttc gccagtattt aagtaattta tgaacattgc
    36961 aaacatagat aatccaaacc cttgaaatcc gactgtcaaa tagcactgta aaatatctga
    37021 caaaacttgt tttgatcgtt gtcctgtttc taagtcagta gcaaatacta aaactccgag
    37081 tacacgtttg aatgctagct cgagtattgc tgtaattata atgaaagcac taaaaacata
    37141 cgctaccgct aaagcaatca atccaaatga aattccccac aggttcgctt gatagcgata
    37201 atatcctgat ttgataccat caacaaaggt tgacaaaaaa ttatctgaaa atttagtagc
    37261 aacaaattca ttatcagaat tttcaactaa ttcataacgc aggttatcag ctgttgagtt
    37321 ctctttttcc attttatcaa ttacattatc tgtcaatact tgcgtaagat ccgttttcca
    37381 aaaattttct tttgttagat tgttccgatc attcgtttta tcgatcatgg aatattgatc
    37441 cgttttattg atataagcta aatcagtaac cccttgttca atcagcgacc atgccacacc
    37501 gccatcttga ttgttaatac tagttgcgtc attataaaga gtctttgcaa acattattcc
    37561 tgaaagtttt tctgttgatc caatcaaagt cggcattaaa agaattaata ctatcgacat
    37621 tacaacattc attccaacag attttagatc aactgttcct tttccagtca ccattttata
    37681 accaataatc actaatgaga gtaccattaa accaataaca actgtattta aaactgactg
    37741 atagactttg ttcaatccag cactttccac aaagctaaac aaatctaaaa cctcgggaat
    37801 catattttga atgccatcga caacagcgaa cattgatttt ataacagacc aacctatcca
    37861 cataccgaac tggctgtaaa aatttccgtt atatttttta agataattct gataaagtgg
    37921 attagttaaa aactcagttt gactctcagt atcatcaaac cagttgaaaa tactgccttc
    37981 tgcaacgtta ctcgtaaaaa taatcatagc tatgagaata agaaaactaa tcaacaacca
    38041 atttattttt ctattatcaa tctttttttt aattattttc attgttacct ccctcagccc
    38101 atttttttag gctctcagaa agcttctgag ccattttttt attaacgatg atgtgagtta
    38161 cgtaatcatc attaacagct cttaaatcta gaacaatagt atttgagcag atactctcga
    38221 ttaactcaag agtatctgcg ttatgatcaa gacagtaaat cttatctact agatgatttt
    38281 caatcaaaat aacccctccc gtagtcaaag ttctcaattt tatgaagata tccctctact
    38341 tcatttaaat caattctatt cttattgctg actaacccgt tgtaaaattc tttttgtaga
    38401 ttatatttat ctgtttcttg aatcttttta tataaatcaa ccagggagtc cctgtcttta
    38461 aaaacttgct tgaattgttc gcttgtatat cggttttcat taattgcaac aactgcttga
    38521 atttcaggcc atttttcttt caacttaaaa taacggggaa cgctgaaata gttctcaaaa
    38581 aagaagtctc gtgcttcata gtattctcta ttttgtcttt ttatatcctc gacaatttcg
    38641 tatcgtgtag agatcttcaa agctgaactt tcgttaattt ctgttccttt tcgaaagact
    38701 ttcacttttg aagggcgttc aattttataa tttatcccct ttttacttga ataacttttg
    38761 atacgaccat caaattgaac catatctcct ttttttaacc acccaaattt tagaaattgt
    38821 ttagttaaat tcatccaaat gtggtctgtg accaactcta agttatcccc ttgaacaatt
    38881 tttaaattcg ataacataaa agtagcattt tcatactctt gaccaaactt gtatttatcc
    38941 tttttatatc cgttaaattc aaaggtacct tgaaatgtat gccgtttctt atctcctaat
    39001 tttttcaatt tttctctcaa aataatcaac tccatcattt aatatatttt tgtgatggta
    39061 gatactctcg attaacacaa gagtatctgc gttgtaatca agacaataaa tttgatatat
    39121 taaccgtttt tcaatcatat tattaatcct ttctaaccta tttttttcag tgtctctagc
    39181 atatccagtc tactagcttt ttcttgctta gctatgtcct cccagtggtt cctagctgtg
    39241 gtgttgataa acttcatttc atcaatttct tcaccgagat tcagtttttc atttatagaa
    39301 ttaaaaagtc ttgttagcat tttgtttgtt atatcaaaat agtcttgacc tcgaatttct
    39361 attttatatt ctctttcaat tgaatctttc atactagcaa tcaacttaag atacttttct
    39421 ctttgaactt cagtatatct atcacctagt ctggtaatta tttgaattcc tttctgattt
    39481 ataatatttt caaaaaagga attctgatct tgattaatct cttctatact atccttatct
    39541 tgattagttt gatcttgact attctgatct tgacttaact gtgtatccga tttgacgtcg
    39601 catggtatac cagctggata ccatttttcc atcagatcaa ctcttaatgg ttctacttga
    39661 ccagactgca aaatcatatc aaattttatt ggctttagct ttgagaaaaa ttctggtttt
    39721 aagttcaata acttgaatcg ataaatagaa ggtttatacc tatcgattcg tatattttga
    39781 ttttgtaacc agtggggtag aaacgctaac aaatcttcat ttaaaaaaaa tacaaaacct
    39841 tttgtaaaaa gtatctttac atcatcatcg ggtgttccga gcattttcgt gtatggataa
    39901 gcttcgacaa ttccgtcatc atctgcgttt gtgttcagat atacgtataa taattttgct
    39961 gaatctgaca tcttcataaa acttgcatta tttaaaaatg atttagccag cattcgtttt
    40021 tctgccataa aaatcacact tcttcctatt tgaatgttaa aatgtagtca aataaagttt
    40081 agctagaact ttattattga gcgttcctag tggtctgcaa actaacggga acactctttt
    40141 ttattcttat taaaaccagc aatactagtt caccttcttt catcctttta catccaatta
    40201 aatttgatgc tgtagcatcc atttttttac ctcttctttt gaatatagtt caattgtgtc
    40261 aaccacgata ataggtaatc ctaacctttt aaacttcaga aaagttccat atgatacgtt
    40321 tagaaatttt gccatttctt ttcccttaag aaaaggtcgt tctaatccgc tgtctattct
    40381 tgcttgatca atagcttctt ttgtcacttc aaacacatgt gtcttcaact gatttgtttg
    40441 atcagtattc aacattacac tgactccgat ttgctccatt aaaaattccc actttcatat
    40501 tttcatcaat aagccaactc gccaagttgt ttgttaataa tctgatttca ataaccaacc
    40561 tattattttt tgataaacat ttttcgacac actttgaact tcgaagcatt caattttttt
    40621 aagagtttgc cttgaaattc caattaattc tgctgcttta gttttcgtaa tcatcaactt
    40681 tcctcgtctc tctcgaattc ttatactaaa atcctcatta atttgaaaca taaacatccc
    40741 tccattttta tttttgcatt tatccgttta tccgatgtcg gataaataga ttttagtata
    40801 tattattttg atagtcaatt aaaaatatac attttggata aaattgttca tttttttatc
    40861 caaatcatat attatagata gtaagaggtg aacttcattg actcaaaaaa acagaattaa
    40921 agaaactcgc gaagaacaga atttaacact taaagaactt agcaatctgt cggatattcc
    40981 gtatcaaact ttgagaaact atgagattgg taaaagaaaa cccagaaatg atgaagtttg
    41041 gtggaagtta ggtacgattt taaacgtccg tgggccctac ttaaaaggag aagatagttt
    41101 taaaacaaat gatgaattgc atatttatta tctaaaaaaa agtcatacaa attttgaact
    41161 gtctaagaaa gaagaaatta tagatataat agataaacta aacgaagacg gtttagatga
    41221 agccttacgg cagttagcac tattatcaaa aatagatgat ttcaagcggt aacttactta
    41281 tcatcatgta gactatcagg tatcataaac taattcctca atcagccaac tcgccaagtt
    41341 atcagattgg agagattagt tatgtcaata caaaagtaca aaacaaaaag cggtacacga
    41401 tatagtgtcc gcttatatgt tcgtaaagat gaaaatggga agcaagaata ctatgtaaaa
    41461 aaaggcttca aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt
    41521 gaagatatgg gctatcacag accttctaat gacttattta gaacagtcta tgaagaatgg
    41581 ttgccgtctt ataaaaatcg tgtacaagaa acgacttatc aacgaacaaa agaccttttt
    41641 cgcttgcata tcctgccaaa gttcggagac aaatcgattt ctaagattac tcctatttac
    41701 tgtcagaatg caatcaatga atgggctgta aaatatacaa atatcaagca acttaaatcc
    41761 tacagctctc aaatatttga gtatgcaatc ttcgcagaat tgttacagcg taaccctatg
    41821 acaaatacca aactgccaaa acaagaaaag aaagaatccg aaaattattt ctcactagaa
    41881 gaattaaaag agtttttgga aattctcaat aaagaagagt ctttaaaaca tatcctgatc
    41941 tttcaacttt taattactac cggtgttcgc aaaggtgaat tatcagccct acgctgggca
    42001 gatattaatt ttgaagaaca gttactacac atcggaaaaa gttatgcaac aattcgcact
    42061 gaagatccga atgctactag aaaaacaatc aggattcaga agaatacaaa aaatgtctct
    42121 tccgaacgaa ttttaccgat tgatactcaa accatcgaaa tgctgaaact ttggaaaaaa
    42181 gagcaagcag aggtactttt acaattcggc attaatgcaa ataccaaaaa gcaacttatc
    42241 tttacctatg taaatgcaaa tggcgatgtt aaccaacctt tacacgcaga ttattccaat
    42301 aatattatga gacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattg
    42361 cgacacactc acgccacttt acttttagaa ggcggtgcga gcattaaaga agcacaagat
    42421 cgattgggtc ataaaaatgc tgaaactacg ctcaatactt attcccatgt aactgaaaaa
    42481 gcgcaacgaa atgcggtaga caagtttatt gcttacactg gattatagac aaaaaagttg
    42541 ccgtcattac ctttttcatt accacaacga aaaaaagcac cttccaactg aatggaaagt
    42601 gcttgaaatc gttggtataa caacgattaa cgcttagaga attgtgaagc tttacgagct
    42661 ttcttaagac ctggtttttt acgttcgacc atacgtgcgt cacgagtaag taagccagca
    42721 cgtttaagag ctaaacggaa gtcaggatca acttctagca atgcacgagc gataccatga
    42781 cggatagctc ctgattgtcc agcgtatcct ccgccgttta cgttaacaaa tacgtcatat
    42841 gcgccttttg tttcagtaac agcgaaaggt tgattgatta cttcacgcaa gtcagcatgt
    42901 ggaatgtatt cttcaacatc ttttttattt acagtaattt tgccagttcc tggtactaga
    42961 cgtacgcgag caactgcgtt tttacgacgg cctgtgccga tatattgaac ttgtgccaat
    43021 gaaattccct cctattagat taagtttgtg atgtctaaaa cttctggttg ttgtgctgca
    43081 tgtggatgtt ctgctccacc gtatacgttc aattttgtaa attgtttgcg gcctaaagtg
    43141 tttttaggaa gcataccttt tacagaagtt tcgatcaaac gacgagaatt tttagcacgc
    43201 aattcgccag cagtgattga tttcaatcct cctgggtagt tgctgtgacg gtaataaatt
    43261 ttgtcagtcg cttttttacc tgttaatttc actttgtctg cattgatgac gatgacgaaa
    43321 tcgccagtat ccaaatgagg tgtgaaagtt ggtttatttt taccacgtag tacagatgca
    43381 acaactgttg aaagacgtcc caatggaaca tcagttgcgt ctactacata ccatttacgt
    43441 tctacttcgc ctggtttggc catatatgtt gtacgcacgt tattttcctc caatttaagt
    43501 tctgatgttt gacatacact tcgagtttcc ggggctcttt gtggggcaaa caataccatt
    43561 taacatatta cccgctaatc tagtcaatgt caacgttttt ctgcttgatt gaaaaattta
    43621 tatgaaactt tacttctttt ctttctttta tataaaaggg tcgtttcctg tcaaaatgaa
    43681 aaacaaaaag aggctgtgac aaaagtcttg tcacaacccc ttattttgaa taaacggtgt
    43741 tctcctgcca actcctcggt cacaagtcac aatatccata aaacataaga agctgttttt
    43801 taaaattgtt tcttgtgact cggagctgaa cggcaggctt acaacctctt ggtaaacggt
    43861 gttcaatcag ctgaccctcg gtattagctc aaaaaacggc aaaatatgag gaactatttt
    43921 gacgtttgtt tctctaatac tcaggtcaaa acgctgattt cacaacctct ttttcggtca
    43981 agttcaacaa cagtttttac gcgtcgatct ctggcgcttt gcccaaatga gcttggatca
    44041 tccagatacg tttttctgtg gctgttttga attcgataaa gatatcttgt gttggatcgt
    44101 cgccttcttc tccagaaact tcgattcctt tttggtaaag atctgctaga taacgatagc
    44161 ctgcaacaag tgtttccaaa cgttctggaa tagtacgatc ccagcggcca atttcatcag
    44221 ggatttttgt gttatctgca aattcacgca atgtagaata aggtgaaccg tctaatgtga
    44281 tcaagcgttc ggatacttca tctaactgag cgttcaaatc atccatgaac tcatccatca
    44341 ttgggtgcaa tgtaaggaaa cctggtcctc tcatgtacca atgtgtttgg tgaacaacaa
    44401 cagacatttg gcttagatct gcaactaatt gatttaatac ttctttggtt tgttggaatt
    44461 tcatctttct tgcctcctaa cattttctta cacttaaaat aatagtagac tttcaatgaa
    44521 aagtacaaca aaatcattta cctgagaacg attttcagtt cgctttttta tccgtaaagc
    44581 caatcatttt tcagaatcag ctaattcttc tcgcagttga gcaaattgct gataagtctg
    44641 tgctaaatgc ttttgtgtcg aaacaaataa tggatagatt ttctgatatt ttttatgatc
    44701 agtttcttgt actccaactt gctctttcaa ttctatcaat tcctgtgctt cactgatact
    44761 ttggatcttt ccgatgcttc tccagcctaa aatcacagct cctaatgcgg atgcttctgt
    44821 gacagtaggg aaaacaagcg ggtaacccag tacatcagcc atcatctgac gaaaaatcgg
    44881 agattgagca aacccgcctg tagcacggat ctctgtgagc tgattttcct ggcaaactcc
    44941 ttttaaaatc cgataaaggt tgagacagat cccttctaga atcgccttca tcatttcttt
    45001 ttctgtatgt tgccgctgta aaccgataaa actgccaaac gcatctgcgt cccaaagcgg
    45061 tgctcgctca ccaagtaaat agggatgaaa aatcagacca ttggcacccg ctggcacaaa
    45121 agcgatagcc gaaagcagtg catcatatgg attttctcct ttttctttag cagattgaac
    45181 gacttcctgt aaaaatgtat gccctgccca atcaaagatg ccagcaccat tgctagtcgc
    45241 tcctcccact acccaatgtt tctgatccag aacataacaa aacgtctcca tttctggatg
    45301 gaactgaggc tgagtagtaa taaaacgaag tgctccgctc gttcctacgg tcaaagcggc
    45361 gatcgtatca ccaaaagcac ctaaccctag attagaaagc ggcccgtctg cccctcccaa
    45421 aacaaatgat atatcatttg gcaaacctag ttctgctgct gtttttgatg gtagacctgt
    45481 tacttgatag gtggaaggaa agacttgcgg caattgctct attcgaatgt tcaagtagtc
    45541 aagcacttct tctgcccatt ggaattcatg gatatcaaaa tatccagttc ctgaagctgt
    45601 tccgtagtcg ctgatcagtt cgccaaacaa tctataaaag atatagtctt tgataccgac
    45661 aaaataagca gtttttttga ataattcagg ttggctgttt tgcagccact tgattttgtt
    45721 caatggtgtc attggatgaa tcggcgtccc agtctgccga taaaattctt tgccaagcac
    45781 ggtatatttc agtttttctg cttcgtccgc tgctcggtta tctgcccaag tgatcattcg
    45841 agataacggt gttttctctt catccaacaa tatcaggcca tgcatcgcag aggagaagga
    45901 gacaaattga atgattgtgt ctgaaggcaa ctgtttaatt acttctttta taacggtgca
    45961 gacaccttga aagatcaatt cctgatcttg ttctgccatc ccttgtgttt cttggatcaa
    46021 agggtagcga aaataagcgg atgctgcttc ttgggcttca tctgtgaaag caactgcttt
    46081 ggtttgtgtg gttccgatat ctaatccgat tgaaacgttc attttttcac ctcaaatttt
    46141 atgtatgtac aaaaatttag tttaagcttg cgtatcttgg ttttgaaaag ggggagatgg
    46201 cgtgttactt tattttatca ttggttgctg tatcggatca tttttatgtt taaccgccca
    46261 gcggattccg ttaggtcact ctattattta tcctagatct cattgtgtca aatgctgtcg
    46321 ttcgctttct tggtatgaat tgattccgat tctctcgatc atcgtccaac gatttcgctg
    46381 ccgctattgc aggtgtcggt tgcccttcta ctatttgttg gcagaagcct tatgtggtgg
    46441 tctttttgcc tggttcttta ctttttcttc cgcaagaaat ttttcgacgt tcatatggat
    46501 gctttcggct ttgctatttt cgttgatgga tttattttac ttcatggtcc attctcacac
    46561 gctattctgt tcttgggcaa ttttatggat tttttggttg caggccggcg tcttccaatg
    46621 gcaaagtgtg ctgttaacgt ttatcgtagg cggtgtgtgc cttcgctatg gtcaatccta
    46681 tctcggagct ggcgatactc tgttgatgct ttcttggagt ggtggcttgt ctctagaaga
    46741 gttgcttcag atcttgtttc ttgctagtct gtttggaata tccgtttttt ctgtttactt
    46801 tatctgtcat aaaaaaaagt tggaaaagct gcctttcatt ccttttttga gcagtgcgtt
    46861 gctgattgtc cttcatctta ggtattgaaa aaaggttgtg acaaacgact tgtcacaacc
    46921 tctgatatat agtgttctct taccaaatcc ttgtgacttg gagctaggcg acaggttcac
    46981 aacctctcca ctaaatggtg ttcaatcagc tgaccctcag tattagctca aaatgctggt
    47041 tttacaacct ctgatatacg gtgttccata agtagctttt tcggcttctt atttcttgac
    47101 gccccaatgt cgacgaagga aacctgcacg tccagaacct tctcgataaa gattgtaatg
    47161 gagcttgttt ttcttgtaat aatcctgatg gtaatcttct gcaggataaa attcgcttct
    47221 tggttcgatt tttgtcacga ttggcttatc gaatcgcccg ctgtcttgca atgcttgttt
    47281 tgaacgctct gcaatatttc gttcttcttc atcattatag tagatcactg gacgataaga
    47341 atcaccgcga tcagcgaact gtcctaatgc gtcagtcgga tcggtttgct gccaatagat
    47401 ttccaccaac tgatcataag aaataacttc tggatcatat tcgatctcta ctgcttctgt
    47461 atgccctgtt gtgcctgttg ttacttgttc ataagttgga tttggtacat gcccgccagt
    47521 ataaccggat gtcacagaaa tgatccctgg ctgctcttca aatggtttga ccatacacca
    47581 aaagcatccg cctgcgaaaa ctgctttttt tgtcatataa aatccccctt ttttctcatc
    47641 ataccttgat ttccaaaagg aggataacgt tttgcttgtg acagaaaaaa cggaaactat
    47701 tatatacgtg atacggcttc tgataaatgc caaaacgaac gtacttgatc aaaaacggtt
    47761 aaatcaggaa tcacatattc agcagaagga agatttatgt tttcacctat tcccaataca
    47821 tgcatgttac cagccaaagc tgcttgacaa ccagcttctg aatcttcaat gaccaagcat
    47881 gcatttggcg gtacattcaa ttgctgtgct cctttgagaa aaacttctgg atcaggtttt
    47941 gcttttgata cttgcgtgcc gtcaataagg acatcaaaat aacttgtcaa attcgttttt
    48001 tctaaaatga ggcgtgcatt tttgcttgct gatcccaatc cgatcttgat gtttgttttt
    48061 ttcaagtact caagaacagc tattgcacca ggcaaaacgg atgtttcatc cattttttga
    48121 atcgcttgaa gatatagatt gtttttttgc tcagcaaagg ctgatttctc tttttctgag
    48181 aatttctgtt ccatttttcc aaatgacagc aatcgctcta gtgactcggt tctggatatt
    48241 cctttcagtt gctcgttttc tttctcagtg aatggaatgg acagctggtt agctaaaacc
    48301 agccacgctt cgtaatgata acgagctgtg tctacaagaa cgccatctaa atcgaatagt
    48361 gctgctttga ttttcatcga ttacctcctt gaaaatgaac gacttgaagt aaagatgcga
    48421 tgtttttagc tgtgcgatga agattatcag tggcttgctg taaagcttct tgtaaaggca
    48481 cagctgcagg aaggatcgga aaaacggccg aaatgccaac atctgctgct ttttcgcttc
    48541 ctttaccaac acttccgcaa atagctatca caggaacgcc ctctggtact cttctagcaa
    48601 tcccaactgg cgcttttcct tttagacttt gtccatctag acgtccttcg cctacgatta
    48661 cgaggtctgc ttgctgtacc cgtttatcga actccagtaa atccaatacg tagtcgatgc
    48721 cagagactat tttccctgaa gcaaatgcta acagtcctgc acccattcca ccaccagcac
    48781 tactgcccga tgcctcgatt acttgagggg caaatctcat ataaaaatca tgcatggctt
    48841 ggtcagccac tgctaattca ttttctttca agcctttttg tggtccgaaa acaaaagaag
    48901 cgccttcttt tccgcataaa agattagtaa catcagtaat gacagtgatt ttggctttaa
    48961 tcagctcaat aggcacgttc gttttatcaa ctgtagcaat tttacctaga ttttctccca
    49021 gtgcttctac tttttgatta tcttgatcgt aaaaagcata acctagacct tctgccatgc
    49081 cgatgccgcc atcgttggta ctacttccgc caacgccgat gatgatgtgt cgaacacctt
    49141 gttgcaacaa ttgtcgtatc agttctccta ctcctcgcgt ggataaccta agtggctgtt
    49201 gttggtttag tgggacatct ttcaatccga cgatttctgc catttcaaaa atcgcagttt
    49261 gaccgtctga agcgtactgg atttctttgt ttttgccaaa tgcattagta acgactgctg
    49321 tttgccgctt caaccttaaa ctgtctgcta atgatgaaac cgttccttct cctccatcgc
    49381 ctataggtag cagatcatat tcagcctgaa caaaaacttc ttgaaaacct gattgaatgg
    49441 cttgtgctgc ctctaaggct gtcagacttt ctttgaaaga atctggcgca atcagaatac
    49501 gcattatttt cccctccgtt ccaagatcag ttctttttcc agctggtatt ggtctccatt
    49561 gacaaaaata ggtaatgttt ctttcgtctc tttttttatt actatttgtt tttttgtcaa
    49621 aacaaatagc aacctgtgat ttttccaaat aaaaggaaaa gaaatttttt cccatgctga
    49681 aggaagtctt ggagaaatag aaagagttcc attcgttact gtaatacctg aaaaaccaaa
    49741 tataactgct agccatagtg ctcctaatga agcagcatga attccgtcat ctgatgaatg
    49801 cggatctggt cctaaatcaa tcaggcacgc ttcttggaat aaatgatacg cccattccat
    49861 ttcttggata cggcaagcct ctatggcgtg aatcgcttta ctcaacgatg agtcgtggat
    49921 tgttttgttt tcatagtaat gcaaattctt agaaacgatt ggttgagaaa aatactcagg
    49981 taataagtat aacagcatga caagatctgc ttgcttgctg acttggagtt catttacttc
    50041 gctacgggca taatcaagta aaatagactg gctgccagga cgttctttgt aagtggtcaa
    50101 atcaataact ggcttactga gatacgtgtc atcttgcgga atcagctgtt ctttgttagg
    50161 cactggcaaa tataacttat ctaaaaaatt ttgacattct ttcaaaaaaa gcggatcgcc
    50221 agcttgatat ttaacagcta aggccacatt ataatgcgcc agatagttcg tatatgcatt
    50281 attgtcgata tattctgtgt attcatctgg accaatgact ctgtgtatct ctaaatgatc
    50341 atcgactttt acagctctgc tcagccaaaa agctgctgtt tcatgaatga gcgtttttcc
    50401 ctttgtttct aaaaacgatt gatcctctgt tgcttggaca tactcttgaa cggcataagc
    50461 aaggtctgca ctgatatgat gttctgcggc agctgaagca acttcttgtc ttgttccggt
    50521 tttgatattc aatgcagcaa atttgggtgt ctcttcctga ccagtgtgtg cgctttccca
    50581 tgggaaaagt gcaccttgat agtgataatc tcttgctttt tgccgtgcgc cttctaatcg
    50641 atcataacgg tacagcagca aattctttgc tacttcagga aactgatata aaaagaaagg
    50701 caggataaaa atttccgtat cccagaaaac atgcccttta taaccttcgc cagttagtcc
    50761 cttcgcccct acactaacac ttggatcatt gcggggagtc ataatctgta aatggtaagc
    50821 agcgaagtcc atcgctaact gatcgaaaga agaatcgcct tggatcgtta tccgatgctg
    50881 atgccaaaaa tctgtccaat aagacatcga ctgctctaaa atttctgtat aactaacgct
    50941 tttctgggct tgggcaatac ttttcttaaa cgggtctgtt tgctgaagag aggtagagag
    51001 cacgatgatc ttctccagcg taaaggacgt attttttctg atcttttctg aaaaggaagc
    51061 ggtgatccgg cgattttttg cttggaatac acctgcttta ttgaatttag ctgcaatccc
    51121 aatatcaatt ttactttctg ttgtctggta ggatgcactg atcaaatcgt caccaaatac
    51181 tcgcagttct ttttcaacca actgctgtgt accaaaattg gtttgctgtc catcgatacc
    51241 cgttttcaca tctacttggc agtcttcggt caacggcttg atgaccactt tcagggctgc
    51301 ctgatggaga ttattttgat cagcaacacg acaagtaatg acttccactt tttttccttg
    51361 agcagtttca atgagcgcat agcgtttaag ctctcccatt tctaaatcta gtgcccgctc
    51421 gtatgcaaga actttcatcg tctcaagaga aaaatgttca ccgtcgattt ttatttccca
    51481 tctgatgaca tctgggagat tcactaactc ggctgattct gctcctaaag gtcggttata
    51541 tacaccagct gcaaacattc cccttacttg attccgatag tcttcctcct ggcttcctct
    51601 gataccaaaa aatccatttc caatggtcat ctgactcgca tacttattga tatactctaa
    51661 atcaaactgt ttttcttcta ctttcataag gtaataactt ctcctgtttc tgccgaacga
    51721 tataaatttt ccaccagatt ctggatgaca tatccttgcc agccatctgc aatcatctga
    51781 gtctggtcac cgagcgcccg attcacaaaa tgagccatac ttagttcatg tgggtcatta
    51841 actggcgtgg tcttttgtaa ggaaaccagc tttccatcta catcttcgaa tagttcgcct
    51901 ggatacagat tagcacctgc ctgatcgcca caaaaagcca cattcagttt gtcttctctg
    51961 atattcaaag caaacgaagt attcagttgg atgatcttgc cgttttctaa ttccagtgtg
    52021 ccaaaaattg catcttctac tgtgaatttg cttggatccc atttcccgaa tttccctgaa
    52081 ttttttttcg taccaatttt ttggaagctg tacgcccgaa cgctttttac tttaggaaat
    52141 ccagtaatat acatcgctgt atcaagcatg tgaatgccat aatcgatcaa aggcccgcct
    52201 ccttgaagtt ctttgtcgat aaacgttccc cagcctggaa caccagaccg acgaagcgca
    52261 ttcgcttcta cgtaataaat atccccgaga acatcaagat gattcttgat cattgttgct
    52321 tcgtcagaaa aacgatgctg gaatccataa gccaaaatct gcccgttttt atcggctgtc
    52381 tctgccatct ttcttgcttg atcagctgtc atagctggtg gtttctcgca catcactgaa
    52441 gcattagctt cgagggcagc caatacatgt tcgaagtgaa agcgattggg tgtacagaca
    52501 ctcacgatat cgggagaaat ctcattcagc atttgtgtaa ctgatgtata cgcatgagaa
    52561 aatcctgtac gtcggcaaaa gtcttctgct cgctggctga ctggatcaac cacagcggcc
    52621 aattctaaga catctgatct tttttgataa taagcagcat gtactttttc tgctacttgt
    52681 ccagcgccta tgattgctac tttcttcatt tatttctccc tcctttgctt atttacttat
    52741 tgttattctt tctctattct ttctctaaat catttaaatg acgcgctgtt tccagacagt
    52801 ttttcaagta ttgcaatgat tcctgataaa ttttcacttc attttctcct cgcaaacgac
    52861 attcatatac catataacct tcatactcat tttgaagtag cgtttgaaaa tggcgagtaa
    52921 aatcaattgc gccagatcct ggttggtagc gatgattatc tgctaaatgg atatgaccca
    52981 catactcttt ttgcgtagtc aatgcttttg aaatatcatc ttcttcaata ttcatatgat
    53041 aaaaatcagc gatgatctgc acatgtttca attgattaga gtcaatgtaa tgacgcgcat
    53101 ccgctaacaa attgatcata tggtcttggt atcggttcaa aggctccaaa taaataaccg
    53161 tacctgtttc ttcggctact ttatctaaat aacgaagtga ttcgctgact gctttatagt
    53221 ctccttcttt gcttcggggt gaaaccatcg gcggtaatcg ataagtgaac attccccaag
    53281 ctgctgggat aacgattcct ttgcctccaa cctcgcttag tgcacgcaaa atctcagcaa
    53341 tttgacgtac accattaaga cgccgttctt cgataaagtc accgatccac ccatcgtagc
    53401 cgttacaagc tgtcactact gggatccctg tttctttgat tgcctgtttg actgtgtcga
    53461 tattttctat taacaactta ccgtcgattt cgtattcttc aaatccacag tctttgataa
    53521 atctaaattt ttctaaaatg tctcttggga aaaatgcttg atcttgcgta ccgaatttca
    53581 ttgttctcct cctcggactt gaacgcccat tttgatactt tcttctgggt gctggtctac
    53641 ataacgcatg taagcttctg cgctttctgc aaatggcaca actggatcaa tgatttcttc
    53701 acaatccaag taaccgttca tcaataattc ccaacatgtg tcctcgattc gtttacggtt
    53761 ccatcttggg taatctgggt ttggttcact agatgctcga gcaaagacga tttttgcatt
    53821 attgaaatgt gcttcgcgac caagattaaa cccagctgga aaaggtttag caaaggcaac
    53881 ataagaaatg atcccgccat agccgatccc tcttaaagaa gcttgtaatg cggcagcact
    53941 gccactcgtt tcaataactg aatctactcc acgtttatct gtcaattcct ttagacgaaa
    54001 accgacatct gctttcatag gatctagcgt gtaatcggca ccgtattttt ctgctaattc
    54061 tctacgctgc gctatgggat cgatcccaac gatggtagta gcacctgctt ttttagctaa
    54121 ttgaatcgca atttgcccga tagcgcctaa accgaagatt gctacagcat cacctgctcg
    54181 aacatgtgct tcccggatac cacctaaagc gaattgagca ggatcgtaac atactgcatt
    54241 tttccattga tccaaccgat caagtttacg tagtttataa ttatcaacac cgtttgtaat
    54301 cagcgtttca cgaatgggtc cataagtgca gactaactct cctttttgat actctgtcac
    54361 caaactgccc gtttcttcga tcgtaccgac aatcatattt cctaattgaa attcgccaaa
    54421 taccacaccg cgttggcttc cttcttctct tggcaagaat aggcgccatt cttctgaaaa
    54481 ttcttcatcg ataaatggac ttaatcctct aaagtcgaca atttctgttc ctggttttgg
    54541 agtagcgaaa attactcgga tacgtacttc gttcttttcg atctcacggt cttcgtaatc
    54601 tttgaatccg gctattcttg gttctaatgc aactaatttt ttcatctttt ctttcctctt
    54661 tcttttcttt ttatcctttt acgccgcctt cgactaaatc acctttaata aatcgttcag
    54721 ataacgcata cataatgatg actggtaaag cggtcaccaa tgaagcggcc atcattcgtc
    54781 cccaaatgta gtctggtgta ctgaataatg tgttcaaacc gattggtaaa gtaaattttt
    54841 cggaggtcga caggaaaatc gaagcaaata aataatcatt ccacgaaacc ataaagcaat
    54901 aaacgaagac agaaatgatt ccagaaatag ccaatggtat aatgatccga ataatgatct
    54961 ggatccggct aagaccatcg atcattgctg cttcttcaat atcagtcgga atcgtgtcaa
    55021 aataactttt tagcatgaat atcgcagtag gaagtgtttg aacgaccatc gtgataatca
    55081 gtgctgtatt ggtatcatac aaacctagac cggaaatgat tttaaataat ggaacaacga
    55141 tcaaaatacc ggaaaacata taaacggtgt aaaagctagc attgattttc gagcgagctt
    55201 tgaagcgtag ttttgacaaa gcgtatgccc cgctgatccc aatcactact gcagttacgg
    55261 aggctatcaa ggagatcact aaactatttt tgaaatacat gatgaatgga aaaatctcag
    55321 cattgaaaat atcctgataa tgttcaaaag tccattcttt cggaaaaata gtttgtgtcg
    55381 ttgcaattgc ttcttgtgaa tccttgaatg atgtcatcag catgatcaaa aatggaaaca
    55441 aattgacagc taatagcaac aaaatcgtcg cgtaaaataa gattttcctg ctctttttat
    55501 ttttcatttc aagtccacct tctttcgtga gagcaagacg accgctgcaa taatgatgaa
    55561 caatagaatc gatatagctg ctgcttttcc aagatcattg aacgcaaagg ctgtctgata
    55621 caaataaacg cctaagatat tgactttatt cgtcagtaga tagacatctg taaacatata
    55681 gaacatccag atagatcgta aaacaatcac agttgctagt actggtttga ttgccggcag
    55741 tgtcacgatc ttgaacttct gccaagcatt tgcaccgtcc atttcagctg cttcataaag
    55801 cgttttgtcg actgtttgca aaatagccaa aaatgaaata aacgcatacg gatagtatct
    55861 ccagatagca aacaaaacga ccataaagaa gctagcaact ggctggtcga accacagcgg
    55921 tgcttcgttg aaaagctgca acctatctac taacagatca ttgacgattc cataactatt
    55981 attgaacata tatttccaag caaaaatcaa agaaatagat ggcgtaacat aacttaataa
    56041 aatcagtgaa cgcaccgttt tcctaaatct gaacttgcgg ttaagcaaaa tagctacggc
    56101 taatcctaaa gctgtactgc ctgctacaac taagaatgtg taagcaactg ttaaacctaa
    56161 agaacgataa aattcactat cacttaaaat ttcaagataa ttgcttaatc cgataaaaac
    56221 ggcgtctgag ttaggattca gcggcatatc gaaaaaactg atctgaatat tggaaagcat
    56281 tggaatcagc actaaaacag ctaataaaag catgcttggt gctaaaagtc ccatggctaa
    56341 ttttaagtca gaatgtttcc ttggacgatt cattgaaacc tccccctgat aatctgccaa
    56401 tagctatcta cttttttcga acaccattgg cagaacttct tgttatttcg tatttttttg
    56461 tgcgtcagct aaagcttgat cgacatcttc gtttccgaca gttacttggt tcactgcttt
    56521 tccgatcaca cctgagcttg tgatatctcc cattttcgtg aaattctttt ccccgactag
    56581 tccaaagact tgtacttcat caaaagcact agcaatctca gatggcagct cgccaaaaga
    56641 cttgatgact tcattttctt tgtaaccatc cagttcgact acttgtttat tcactggttg
    56701 agcaccacca ggagacatca agacccactt ttccatgttt ttcggttgag ataagaaagc
    56761 tgtgaatgct tcagcagcct ctttttgttt ctcgtctaga ccagaagaaa tcgtcaatcc
    56821 agatactgtg ccatagacag cttgatcttt ttgtgttggg atagcaaaac cgatattttc
    56881 tgagttcccc gcttcataaa cagaaggcaa aatgtaagtt gaatagattg ccattggtgc
    56941 tgttccattc atgaaagcat ctttgatttc tgtcacatca ttagagcctg gcatcgtgta
    57001 ttgggataag ttttgataaa acgacaatgc ttctctcatc ttttccgtat cgatcgttac
    57061 ctcgccttca tcatccaaaa catttgctcc atttgacaaa gcaaattgag agaacgcttg
    57121 ctcactcatt gttccttcag cagtaggcat agcaattcca tattgtttat tctctttatc
    57181 tgtgaaatgt tgagcaattt ttaaaatatc atcccaattt tctggttctg aaaaaccagc
    57241 ttctgataat ttttctttgt cataccaaat accttgaacc cagccgctaa ttggtgcagc
    57301 aatatagctt tttccatctt ctgaacgaac aaggtttttg gctccgtcat aataattatc
    57361 ttctccagct tcctcgataa cgttttggac tgccgtctga tcaatcagtt catctttatc
    57421 catcacttta gcaaaatcct gactgacttc cattacttct ggtaatttac cggaacgagc
    57481 taacgtaacg atttttgtat tgaacgctga ttcttctacc ggcacttgct tgattttgat
    57541 gtctggattt tctttttcaa aatcagcaac cagttcattg atcacactta atcgttcctg
    57601 ttcgacagaa gagtgcatga attgaatcgt tgtctgttgt gattcgttag agctttgact
    57661 ttcaccacaa gcagtaagaa gaaatccagt agctagcaga caggtagtaa caataatttt
    57721 tttcattttt ttccacctct tattttatta ttttcagcca catatattca tacggctgga
    57781 atatcaactt tcgttcttga ctgcaatgga taatttgtcc agaaaacagg tctaggtaat
    57841 ctccttttgg taaaagataa cctgctgatt gattggaaaa attatggata actaagactt
    57901 tctcttcctt cgcttcgcga ataaaactga taaaagaatc tgctgagtcc agtaagtaaa
    57961 tcaaactatt cggatggaag gctttttctt tttttcgaat agatagcatc tgggtcaatt
    58021 caccatatac tgctgttctt aatggatctg tctgcaactc tttctcaata tctgctaaca
    58081 aaaatttttg ccgattgatt tttcgattct ctcctgtttt ttctacgcct ttgtaatcat
    58141 ttcgacttcc cagcacactt tgaatataaa ttgccggcac gcctggtaac gttaccaaaa
    58201 atgaatgagc agctaaaaag cgtttgcttc tccattccgt cgtatctgtt ggagaactta
    58261 acgcatctag atacgtagcg tttatctcat atggactggt cgttccatct gggtttttct
    58321 tgtagtttac tcgggcaccc tctttcttca gctgttccac taattcaagg atcgtttttt
    58381 ccggcagaat acctcgtacc ggattcaatc cgataccgtc atgggaggct aaaaaattaa
    58441 aaaaagttgt ttttttcgat gcgaaatcga tggtttttaa ccattctttc aacttacttg
    58501 tattacccga acgaatcgct tgaagggtca aaggtggtag cgaaaactga tagaccatct
    58561 gtgcttcatt ctcgccattc ccaaaataac tgatattatc tttgtgtggc acatttgtct
    58621 cagtgatcaa taccgttcct ggagctgctt catcagcgat tgcacggaat aattggatga
    58681 ttttatgcgt ttctggcagg tgtatacaag aagttcctag ttctttccat aaaaatccca
    58741 cagcgtccaa gcgaataaat gaagcgcctt tttctaagta aaacaaaaga atatcgatca
    58801 ttttcaataa aacttctgga tttttaaaat tcaagtctac ttgatcttcg ctaaaagtcg
    58861 tccatacgtg tttttctttc ccgtttttgt caatgaacgt tgtaagtaac gggctggtcc
    58921 ttggtctagt cacgctgctt gtatctgtat ccagtggcaa atcaataaaa aaatctttgt
    58981 acgtatcatt caagtttaaa tattcctgaa accaagtact ttcggcagac atatgattgc
    59041 agacaaagtc gaacattaac cgtgtttcgc ttctcatttc ttctatatct tcccatgtgc
    59101 ccaaacggtc gttgattgcc tgataattta caacggagaa accatcatca gatgtatatg
    59161 ggaaaaatgg caagaaatgt acaactctaa atgtatctgc caaatacttt tgataaaatt
    59221 tcttaaatgt acgcaaagtt ggttgctgct cttcaaaaaa ttgatcccca taagtaatca
    59281 agaaaatatc ttcttcgtcc caatgcagtt tgcctgcctg gcctttcttc tgctgataaa
    59341 cactgacttt ttgttcaatc atagaggcgg ttttctcaga caaatctgag tcgcgataaa
    59401 tcgcttgtaa aagttttgta tacatcggat tcccctttct tttttgggag cgttcccaac
    59461 gatttgatca tattatggaa aacgcttact gtcaatagca tttttttaaa taattttgat
    59521 atacacaaaa atacaaataa gaaagcttat gtatcaataa ttaatagctt cttaaaaaaa
    59581 tatggtctct catgatcatg caagctattc ctaaattttc aaaatcatag acaaaaaaga
    59641 atgtctattg tactatggaa ttattctaaa acgctcccaa aaaggaggtg catataaaat
    59701 tgaaacctac tatttatgac attgcgaaaa aagctaatgt ctcaaaatca actgtctcca
    59761 gagtattaaa taaccagcca aatatctctg ataaagcaaa agcaagtgta cttcaagcaa
    59821 tcaaagaatt gaattatgaa ccgagcaaaa ttgcaagagg actgtcagga aatggttttg
    59881 acgcgattct agcattatct catcgtactt ctcatacgac ctatggcaat cctttttttt
    59941 cagatgttat tcaatccatt tctgccgttt ctgaacaaaa taacttcgac ttgattctac
    60001 aaacggcaaa aacaccagaa gaagagctag aaaaatgcgc gaaaaagatc caagaaaaaa
    60061 tgatccgagg aattattatt ttaagctcta cgatggatga aacacttctt tttgaattgg
    60121 atcaatacaa tattcctatt gtggtaatcg gaaaagtcgg aaacgactac acgaacatct
    60181 actcagtgga cacggataat ttccaggata gttacgattt ggtggaaaca ctgatcaaga
    60241 atggacaccg tcatatcggc tgtctccatg ctccgacaga agtttatgta tccaatgatc
    60301 gtctcaatgg ttaccgtcaa tgcttatttg atcaccacct agatatccgt aatgaatgga
    60361 ttatagacgg cggctttcgc ttagaagata gcatggcagc aatgaatgat ttaatgaagc
    60421 tacgagaaag accaactgcg attttttcta ccgatgcatt aaaatcattg agtatttaca
    60481 aagtggcaga acaatctgga aagcagatac ctgatgatct ttcgatcgca ggattcagtg
    60541 atcccttatt gtcctcccta ttttcgccac agttgactcg gatagacatt ccgacaaatc
    60601 agttaggaat caaagccaca gaacttttat tccaactaat ccaccaccaa taccctgaag
    60661 aaaaaagaat cattctttca accgagatta ctctcacaga ttcgatccaa caacaagaaa
    60721 tgtagaacag aattataaaa gaacagaaac actgaggata agtcagttac tctgttcttt
    60781 tttcaatcac tcatccctcg ttaccccctc ccggtatttt agcgaatttt tcttattttc
    60841 catctgtttt agatagctgt ggataactat aatgtttgtg ttaaactatt ttttccacag
    60901 ggaagaaaaa actattttta accacgttgt gtataagttt ttatagttcg tttttttaaa
    60961 cacatttacc cttatttcaa tccatgttat ttggggatac ttatctctaa aacataaata
    61021 gaataacaga catgtctact ggttttgttt tattcgagga attattcaat aatagctagc
    61081 aaaatattaa aaataaccgc tctatcttcc catcaattta ttttgcattc aaaaaatgat
    61141 ctatctttac ttttgttgat tgacttctct tggaagatga tcgttccgat accttaattg
    61201 gatacgaacc gatgttgtta agatcctttc ccacttttct tctagttaga caaattattt
    61261 tagacaaacc aaaaaagagg ttgtgacaat aatttgtcac aacctctttt ttaaaatatc
    61321 tattttgttt gattgttcat tgcgtcttct gcagccattt gcgcttcaat atctgaaata
    61381 ctgtagacat tttcgcttgc tacaccgact tcttttggtt ccatgtcacg ataacgttgc
    61441 ataccagtac cagctgggat gatcttacct ataataacat tttctttcaa accaagaaga
    61501 ggatctttct taccgcggat cgcagcatcc gtcaagacac gagttgtttc ttggaatgat
    61561 gcagcagata agaaactatt tgtttctaat gatgcttttg tgatacctag taagacaggt
    61621 cgagaagttg caggaacgcc tcctgagact agcgtattgt agttttgatc tttaaagtct
    61681 gcgatgtcta ataatgtacc tggtaagata tctgtatcac ctggatccat tacacgaact
    61741 ttacgcagca tttgacgaac cattacttcg atatgcttgt cgccgatttc taccccttgc
    61801 atacggtaaa cacgttgtac ttcacgaagc aagtagtttt caacagataa tacatcgcga
    61861 acttgcaaca attgttttgg atcgattgat ccttctgtca atggtgcacc acggtggatc
    61921 atatcgcctt ctgctacttt catacgtgct gtataaggaa cagtatacgt acgtgtatct
    61981 gtttttcctt tgattgttac ttctttggta cgtgttgcag gatcttctga gatatcgatg
    62041 acatcccctg ttacttctgt gatcactgct tgccctttcg gattacgtgc ttcaaagatt
    62101 tcttggacac gaggaagacc ttgagtgata tcgtctccgg caaccccacc tgtatggaat
    62161 gtacgcatcg tcaactgagt accaggttca ccgattgatt gagcggcgat cgtaccaact
    62221 gcttctccga cttcaacgtc agagccagtt gcaaggttgc gtccgtaaca atgtttgcag
    62281 acaccatgtt ttgtattaca tgtgaagaca gaacggattg tcactgtttc gacacctgca
    62341 tcaacgattt gttttgcgat gtcttcggaa atcaattggt ttcctgcaat gatcaattca
    62401 tttgtttcag gatgacgtac ttctttacgg gtgtaacgtc ccactaaacg atcttctaat
    62461 gattcgatga tttcatttcc ctcgcggatg gcttggattt caagacctcg gtcagtaccg
    62521 caatcttctt cacggatgat tacatcttgg gccacgtcaa ccagacgacg agtcaagtaa
    62581 cctgaatcgg cagtcttcaa ggctgtatcg gtcatccctt tacgagcccc gtgagttgag
    62641 ataaacattt ccaagacgga tagtccttca cggaagttcg aaatgattgg caattccatg
    62701 attcgaccat taggagcggc catcaaacca cgcattccgg caagctgtgt aaagttggaa
    62761 atgttaccac gagctccaga atcagacatc atgaagattg gatttttcgc ttccaaacct
    62821 tccatcagtt tttgttggat gctgtctttt gcagcattcc aaacagcaat gacacgttca
    62881 taacgttcgt catctgtgat cagaccacga cggaattgtt ttgtaatagt ttcaacttgt
    62941 ttatgggcat tttcaatgat ttcttgtttt tcattcagta cactgatgtc agcgatccct
    63001 actgtgatac cggcatgtgt cgaatgtttg taccctaagt ctttcatacg gtcaagcatc
    63061 ttagaagttt cttttacttt gaatcgtttg aagacttctg cgatgatgtt tcctaagttt
    63121 ttcttcttga acggtaatac taattcttgc tctttgatat gtgcaggaat atcagtacca
    63181 gcttcaacaa agtatttgtc cggtgtttgg acggtcaagt tgaagtctgt tggttcattc
    63241 agataaggga attcaggagg catgatctcg ttgaagatga tcttaccaac tgttgtgatc
    63301 atcgtacgtt ctttttgcca ttcagtaaat ggtttttcac ctaatgagtt agggttcaca
    63361 ccgatacgtg aatgtaaatg aacatatccg ttgcgccatg cgataacggc ttcgttttga
    63421 tctctgaaga ccattccttc gccttcgcgt ccttcttctt ccattgtcaa gtagtagtta
    63481 cctagaacca tatcttgaga aggagtaaca actggtttac catctttagg gttcaagatg
    63541 ttttgagcag ctaacatcaa catacgtgct tctgcttgtg cttcttcatt caatggaacg
    63601 tggacagcca tttggtctcc atcgaaatcg gcattataag cttcacatac aagtggatgc
    63661 aaacggattg cgcgtccttg tactaaaact ggttcgaatg cttggatacc aagtcggtga
    63721 agcgtaggtg cccggttcag caatactggg tgttccttga ttacgtcttc taaaacatcc
    63781 catacttcgt cttcttgacg ttcgatttta cgtttcgcat ttttgatgtt tgaagctagt
    63841 tcgcgttgaa caagctcacg catcacgaat ggtttgaata attcaatggc catttctttt
    63901 ggaagtccac attggtacat cttcaagaaa ggtccaacaa cgataacgga acgacctgag
    63961 tagtcgacac gtttacctag caagttttga cggaaacgac cttgtttccc tttcaacata
    64021 tgagaaagag atttcaatgg gcggttacct ggtccagtaa ctggacgtcc gcgacgaccg
    64081 ttatcgatca atgcatctac tgcttcttgc agcatacgtt tttcattttg aacgatgatt
    64141 ccaggtgcat tcaagtctaa caaacgtttc aaacggttat tacggttgat tacacgacgg
    64201 taaagatcat tcaagtcact tgttgcaaaa cgtccacctt ctaattgaac cattgggcgt
    64261 aaatctggtg gaataacagg gataacgtcc ataaccatcc agcttggttg atttcctgaa
    64321 gcgcggaatg cttctaaaat atccaaacgg cggattgcac gtgtacgttt ttgtccttgt
    64381 gcagatttca attcttcttt caattcggct gcttctgcat ctagatcaac attatcaagt
    64441 aattgtttaa tcgcttctgc acccatagca gcttggaatt cttgtccata ttgttcacgt
    64501 ttttcgcgat attcgcgttc tgtcaacaat tgttttttct ctaaattcgt atttcctggt
    64561 tcgatgacta catatgaagc aaaataaatg atttcttcca aagcgcgtgg gctcatgtct
    64621 aatacaagac ccatacgtga aggaatccct ttaaagtacc agatatgtga aacaggagct
    64681 gctaattcaa tatgtcccat gcgttcacgg cgaactttcg aacgagtaac ttccactccg
    64741 catcgatcac aaacgattcc tttataacgg atacgtttgt attttccgca ggcacattcc
    64801 cagtcttttg taggaccaaa aatccgctca cagaacaacc cttcgcgttc aggttttaag
    64861 gtacgatagt taatcgtctc aggttttttt acttcaccgt aagaccagct tctgattttt
    64921 tcgggagaag ccaaacctat ttgcatactt tcgaatttat ttacatcgat caaaaggggt
    64981 tccctccatt tcatttaatg gcaaaccgca agacggctga tcttcgaccg ccttgcagct
    65041 catagaccgg attagtctaa attatcttct gcggtttcaa agttttggat gacatcgtct
    65101 ttttcatctt ccacttgttc agcagctttc ttttctaatt ctttggcagt ttgctgttcg
    65161 gcaaattttg tcaaagcatc aacagtgatc aaatcgtcgt cttcatcgtc catgtcgcga
    65221 agttcgatct ctgtttcttc gatatccaag acacgcatgt ccagacctag tgattgcaat
    65281 tctttcacca atacgcggaa tgattccggt acacctggtt ttggaattgg ttcacccttg
    65341 acgattgctt cgtatgtttt cacacgtccg actacgtcat ctgatttgta tgtcaagatt
    65401 tcttgtaaag tataagccgc accgtaagct tccagtgccc atacttccat ttcaccaaaa
    65461 cgttgtccac caaattgagc tttacctccc aatggttgtt gtgtaaccaa tgagtaaggt
    65521 ccgattgaac gtgcatgcaa tttgtcatcg accatgtgag caagtttgat catgtacatc
    65581 acaccgacag acacacgtcc atcaaatggt tcacctgtac gtccgtcgta cagaacagtt
    65641 ttcgcatcgc tggccatacc ggcttcacga actgtttccc atacgtcttc atcacttgca
    65701 ccatcaaata ctggcgttgc tacgtggata cctaactgac gtgcagccat acccaagtgt
    65761 aattccaata cttgcccgat gttcatacgt gaaggcaccc ctaaaggatt cagcatgata
    65821 tcgattggtg ttccatcagg taggaatggc atatcttctt ccggcataat acgggataca
    65881 acccctttat ttccgtgacg accggccatt ttatcccctt catggatttt acgtttttga
    65941 acgatataaa cacgaactaa catgtttacg cctggtgaca attcatctcc agcttcacga
    66001 gtaaagattt tcacatcgtg aacgataccg ccgccgccat gtggtacacg taatgatgta
    66061 tcgcggactt cacgagcttt ttcgccaaag atcgcatgca atagacgttc ttctgcagat
    66121 aattctgtta ccccttttgg cgtgactttc cctacaagca aatcgccatc ttggacttct
    66181 gcaccaatac ggatgatacc catttcgtct aaatctttta atgcgtcttc cccgacatta
    66241 gggatttcgc gtgtgatttc ttcaggtcct aattttgtat cgcgggcttc tgattcatat
    66301 tcttcaatat ggatagaagt gtatacgtca tcttttacca aacgacggct catgatgatc
    66361 gcatcttcat agttgtaccc ttcccaagtc atgaaaccaa ctaaaacgtt ttggcctaga
    66421 gccatttcgc cttgttccat agatggtccg tctgccagag tatccccttt ttcgactttc
    66481 tcacccaaat gaacgattgg acgttggttg tagcttgttc cggagtttga acgacggaat
    66541 tttgttacat cgtatttatc taatgcaccg ttgtcgcggc gtacgcggat ttcagaagca
    66601 tcaacgtatt caacgacacc atcatgttta cataacaaag cagctcctga gtcatgcgct
    66661 gatttgtatt ccataccagt accaacccat ggtgcttgag gattgatcaa cggcactgct
    66721 tgacgctgca tgttggcacc catcaaggca cggttggagt catcgttttc caagaaagga
    66781 atacatgctg tcgcaacggc aactacttgt ttaggtgata cgtccatgta gtctacttta
    66841 tcaatagata cttctaagtt ttcactttga gcacgagcca taacaacgtc ttgagcaaat
    66901 gttccatctt cattcaatgg gctgtttgct tgggctacga tgtaatggtc ttcgatatca
    66961 gctgtcaagt agtcgatttg gtcagtaaca cgacctgttt cacggtctac acgacgataa
    67021 ggtgtttcga taaatccgaa tttatttact ttcgcataac tggacaaact attgatcaac
    67081 ccgatgtttg ggccttcagg agtttcgatc ggacacatac ggccatagtg ggagtagtga
    67141 acgtcacgaa cttcataacc ggcgcggtca cgagtcaatc cgccaggtcc taaggcgaaa
    67201 agacgacgtt tgtgtgtcaa ttcgccaaga gggtttgttt gatccatgaa ctgtgacaac
    67261 tgagaagaac caaagaattc tttgatactt gccacaactg gacggatatt gatcaattgt
    67321 tgaggtgtca atgtttcagt atcttggatc gacattcttt cacgaaccac acgttccata
    67381 cgtgctagcc cgatacggaa ttggttttgt aaaagttcac cgactgaacg gatacgacga
    67441 tttcctaagt ggtcgatatc atcgacattg ccgatacctt ccatcaagtt caagaaatag
    67501 ctcattgaag caatgatgtc ggctggacga accgttttta cagctgcttc tggatagccg
    67561 tttccgatca cgtttacttc acgttcaggg tctcttggtg aaaatacttt gatgacttgg
    67621 acagtcattg gatctgtgac cacaccgtct tctgatggat agtaagtcac tgaatttagg
    67681 ccattatcaa tgaaaggagc tagtgtttcc atgacttggt gagtcagaac tgttcctttt
    67741 tcaacgatga tctcgcctgt ttctggatca actaatgttt cagctaatgt cagattcaat
    67801 agacgtgttt tcaaatctaa ttttttgttt actttgtaac gaccaacgtt tgctaagtcg
    67861 taacgttttg gatcgaagaa acgagcattc agcaagttac gtgagctgtc tgctgttttt
    67921 ggttcgcctg gacgcaaacg ttcgtaaacg tctttcaaac cttcttctgt tcttgagtcg
    67981 cttgcgtttt tatgcaagtc tttttcgact gtattgcgta atgtttcgct gtcgccgaag
    68041 atttcaaaga tcgtatcatc ggaaccaaat cctaacgcac gaactaatac ggttaaagga
    68101 atcttacgtg tacggtcgat acgtacataa gagatgtctt ttgcatcagt ttccatttct
    68161 agccaagctc cacggttagg gataacagta gaaccgaatc cttcttttcc gtttttgtcg
    68221 acttttccat ggaaatagac acctggtgaa cggactaact gagaaacgat tactcgctct
    68281 gccccgttga tgatgaatgt tccttgttct gtcattaatg ggaaatcacc gaagaatact
    68341 tcttgtgctt tgatttcgcc agtctcgcgg tttgtcaaac gcaatgttac atgtaatggt
    68401 gcagagtagt ttgcatcatg cgcacgagct tctgctactg tatactttgg ttctttcaat
    68461 tcataatcta caaattccaa agatagattg ccattgaagt catcgattgg caaaatgtct
    68521 tcaaacattt ctctaagtcc ctcatctaag aaccattggt aagagtctgt ttgaatttcg
    68581 atcaaatttg gtaattccaa cacttcactg attcttgcga aacttctacg ttcgcgatgt
    68641 tttccgtatt ttactacgtg tccagccaag ctcttcaccc ctctaaaatg tcattcaaaa
    68701 agactacccg atcaattgtt acaataatat ttcaaatatt atttttaggt aacaacagac
    68761 attttttgcg gcttttaggc aaaaaaaaac caaaaataga acattctctt gaaaccttac
    68821 ttcgtgagct tctacttttg tttccttata ttaaagccga aacggacaat atttcgtttc
    68881 tgccttttct tcatcagata gtttttgcaa cttcatatac tacacttatt ttctataaaa
    68941 gtcaacactt cctggcgttt cttctgcttt ttcgcaacat tttcttaatg ttttcaattt
    69001 tatgttttca attatctgac aattcttaat tgacagacct ttttatctcg gttatacttt
    69061 agaaaattca ttttgtggag gaacttctat gcgaaccaac atcaaccaaa tcgcaccaac
    69121 acaactgaat aacttttact ttagctactt tagataggtt tgtattcatc atgatggata
    69181 caaacgttaa acgacagttt gtatctatga tggctaaaga actttgtatt gcagcaaaaa
    69241 gccacgtaga caaaatgcta agtggctgag cagtgaaaat acaaagtaaa agtatcaagc
    69301 attctacttt ttcaatttat tttccgactt ttcaatccat ttggacattt tgtctgaatg
    69361 gattttttgt ttcccaaaat taaggaggaa aaagaaatga aaaaaaatat aatcatcgga
    69421 ttaggcgctg ccctgctact agctttagga ggttgcgcac aaaaagacaa ttccgcagag
    69481 gcatcagatg gacaaaaaac aattggcgta ttgcaacttg tacaacataa ctcgttagat
    69541 gctgcctata aaggattcaa agaaggatta gcagaagaag ggtataaaga aggcgataat
    69601 ctaacaatcg attatcaaaa tgcccaaaac aatcaagaca acctgaaaag tatgagtgag
    69661 aaactcgtca aagaagatcc tgatttgcta cttggaatcg ccactccagc agcacaatct
    69721 ttattaaatg aaacaaccac tatcccgatg actgtcacag cggtcacaga cttggaacaa
    69781 gcccatttag tcacatccaa tgaaaaacct ggcggcaatg tgactggcac gacagatatg
    69841 gtgccaatcg aaaaacaaat cggcttactg ttaaatatcg tgccagacgc caaaacaatc
    69901 ggcatcatgt ataacaacgg tgaagcaaac tctaagatcc aagctgattt ggcagaaaaa
    69961 gaattgaaaa aagcgggcgt caaagtcaaa gtactgacag caaattccac aaatgatgtc
    70021 caacaagtga cgaaaagtct agctaaagat gtagatggaa tctatattcc tactgataac
    70081 acgttcgcaa gtgcggcaag tgttgtcggt gaagtcgcaa aagaaacaaa aacacctgtc
    70141 gttgctggcg cagttgatca agtcaaagac ggcggtctag caacagtagg aatcgactac
    70201 gaaagcttgg gcaaacaaac agggatcatg gcagcaaaaa tcttagacgg caagaatcca
    70261 agtgaacttc ctgtcgaaac agcgaatgat ttggaactgt atgtcaataa agacatggcc
    70321 aaagcattag gcatcaatcc agacagcatc aaagaagctg aataaaacac aggaggattc
    70381 tcatgacaaa tttgctctct cttttcttat catctgcatc gcaaggggtc ttatgggccc
    70441 tacttgcgat tggtgtatac gtcactttcc gtatcttgga cattgccgac ttgactgctg
    70501 aaggaagctt tcctttaggt gcagggatcg cggcagtaag tattacaaat ggctatcatc
    70561 cattgacagc ttgtcttcta ggctttttag ggagtgcggc agcagggctt gtttccggac
    70621 tgcttcacac aaaattgaaa attcccgccc ttcttgcagg gatcatcacc atgactggtt
    70681 tatattctgt cacatcccgt gtgatgggtg cgccgaacat ctctttattg ggtcagccaa
    70741 cgatctttca ttgggtcgag tcattcggca taacaaaaga caacgctgta ctgatcgtcg
    70801 gtctgctttt tgctttgatc gttgtatgtt tacttgtttt gttcttacgt acagaaacag
    70861 gacttgctat tcgtgcaact ggcgataatc tggcaatgag cgaagcaaac gggatcaaca
    70921 cagataatat gaagatcatc ggttatatga tttctaatgg atgcattgct ctttctggct
    70981 ccttgcttgc gcaaaacaac ggctttgctg atttaaattc tggtattgga acgatcgtaa
    71041 ttggacttgc ttctattatc atcgcagaag ttttgttacg taaccagcca ctatttctcc
    71101 gtctcttgac tgtcgtttta ggtgcggtca tttatcgttt tattttagcg ttagtcttcg
    71161 aactgaatgt tgaaccaagt gattcgaaac ttgcttctgc tttcgtgcta gtgatctgtc
    71221 tttctttccc gcagatccag caaaaattcc atttacctca aaaaaagaaa ggcggtagtg
    71281 tcaaatgaat gacgtcttaa cattggaaaa tctccatcat acctttgaaa aaggaacgat
    71341 caacgaaaat catgtcctga aaggcattaa tctttcctta gatcccggcg acttcgtgac
    71401 gatcatcggt ggaaatgggg ctggtaaatc tactttgctg aacagcatcg ccggtacatt
    71461 ttctgtcgat cagggtcaaa ttttattgaa tggaaaaaat atcacgaaaa aatctgttgt
    71521 cgaacgttcg aaatccatca gtcgcgtatt ccaagatcct aaactaggga cagccgttcg
    71581 tttaacggta gaagaaaatc ttgctcttgc tatgaaacga ggaaaaaaac gcggcttctt
    71641 ccgtggtgtc aaaccacaag accgaacatt tttcaaagac cagctggttc ggctaaattt
    71701 ggggttggaa aatcgtttat cctcagaaat cggtttgctg tctggaggac aacgtcaagc
    71761 tattacgtta ttgatggcca cattacagcg tccagaactg atcttattag atgaacacac
    71821 tgcagcgctt gaccctgcta cttccaaaac ggtgatggaa ttgacagaaa agctgatcac
    71881 tgagcagaat ctcactgctt ttatggtcac tcatgacatg gaagacgcga tccgctatgg
    71941 gagtcgactg atcatgctgc atcaaggaag gatcgtcgta gatatccagc aagaggaaaa
    72001 acagcagctc acagtgcccc aattattagc gttgttcaaa caaaacagcg gcacggcatt
    72061 aaaagacgat caagtacttt tatcttcata atcagaaaga ggatgggaca aaaaatgaac
    72121 gcccaccctc ttcttttttc tctttccttc tttcgttttt gctttatgta tcaaccgttg
    72181 tttcttcgaa aactattttg ttctctcctt cttcctgata gaatggatgg gaaaggagct
    72241 tgatgccatg acaacgaaag acaaggtact tcaattattg aaaaagacac cagattttct
    72301 ttccggagaa aagttggcac agcaactgga agtttcccgg acaagtattt ggaaagccat
    72361 caaagaattg gaaaaggcag gctatcgttt tgagcacggg cctacagggt atcgttacct
    72421 gccctctgac gtactagatg caaaagaaat ccagcaagag ctacggtcgt ttattcctga
    72481 tttgaaagta caaacgatgt tgacttctga atctacgatg aaagatgcca aactggcagc
    72541 agctcaagga gattctgttt cgaagttatt tgttgctgat acacaagaac aagctcgtgg
    72601 acgttttgga cggccttttt tcgctgaacc tggacgagga atctacatga gtctcttgct
    72661 ccatccagac aaacggtttg atgaattgcc tcaatatacg atcatcgcag ccagtgcctg
    72721 tgtgaaagcc attgaatctg taaccggtcg ttctgcttcg atcaaatggg tcaatgatat
    72781 ctacatggat ggaaaaaaag tctgtgggat tttatctgaa gcagtcagtg atatggaaag
    72841 cggcaggatc agtcatatca tcattgggat cgggcttaat ttttctgttc ctcaaaatca
    72901 ttttccagct gatctccaag aaaaagccat ctctgtcttt cccgacggac aagctagtgt
    72961 cacaaggaat cagctaatca gcaaaatctg gcaagaattg ttcacttatc tttctcaccc
    73021 agaaaaagcg ttggacttct ataaagaaaa atcattcgta ttgggaaaaa ccgtgtcgtt
    73081 caatcaaaaa ggaacgactt atgtcggtct tgcaaaagaa atcggtgatc atggcgaact
    73141 gatcgtccaa acaaatgaac agaagatgag tttgtcttct ggcgaaatca gtctcacatc
    73201 tatccgtacg caataattat cagatttcac aaaaggacac ctgatctcat acagtgtcct
    73261 tttttctgaa ttctcttcaa aagactctcc ttattctatc agctgacagt ttctctatcc
    73321 tctagaaaaa ggtattctaa aaatatctat aaagcatggt acactttctt taaatgaatc
    73381 aatgcaaaaa acaagagagt catcagttta cacgatcaaa agagatagca ggccgcttcc
    73441 tttttcaatc ttatagatag accatgggta acgataaaaa caaaaaagaa cttgcgactt
    73501 attttgccgt aagttctttt ttagctagtg ccttaatctc ttaatcccaa caaacgtctc
    73561 gcatagatca cctgaccaga gtgcatagca gcatcatcaa taatagaaac gagacgcatt
    73621 cctcgtgtga ctggtggtgt ccagttctcg tcaattactt catctagctc ggaaggttcc
    73681 agccttctta agtaagaaat agcaaaatca gcagctcctc gcaagtatcc tagcagatct
    73741 tctatttgat tagcttggat ctgctttgct tgttccagac tatgcttcca atcttgttcg
    73801 ttatctgcta tcgtcatcgg aaaccggctt tcccagtctt gactatgcca aattggagaa
    73861 gttcctgcta aatcagcaat ctggaaatct aattctcgag cggtatgcca agccagccaa
    73921 gtcattgatt tgatctgcgg ggctctatct tccactggaa aacgattggc ctcctcaata
    73981 gagacgcctt caaacaaacg ttcaaaccga tcgtatgccc gatccacact ctcgcatagc
    74041 atatctaaat aatccattta ttttcctcct ttttatttat cctacttact ttttcctaat
    74101 tctaggatac ctacttatat gttactacac acccttattt tttacacttt aacagtcacc
    74161 atcatcaata gtttggagat tgaaagaaaa agatagtgtc gaactatcaa ttgaacaaga
    74221 agcaacaata tgaacgtttc attaatattc tttaaataaa caatgatttt tcaaacgaac
    74281 agtttaagac taggagaaaa agagtataat aggaaaatgt ttgaaaggaa aggaagggga
    74341 aaaatgaaaa aaagggcaag tttactagtc ctagttgctt tgttgttcaa tatcttttcg
    74401 tatggtgtgg ccgtttcagc ggaaacatac attcctaaag accctgggaa tatttataat
    74461 gatctaactg gtaactatgg cttgttagga attgctagtc aattccacgt atttgctaaa
    74521 aataagacaa ctgtgaatgc acatacagac ggaaatatag caacacatga acttgatgca
    74581 aaaaataatt ttggtacaga gcttcatgaa ggtttattga accaagaaat aaattatata
    74641 caaaaaactg attctttcgc taattcttca ggcataccta caggtagcac aagaatgaat
    74701 aaatttgtcg ttggcagtaa cgtggatgta gcacttcaag atggtcatcc tacagtcaat
    74761 ggatccaggc ttgatcactt aactccagat gatttttata aagatcgtgc tgggcatgaa
    74821 tatattgatt tcgagcagga atttgctaaa ttgaatgtag cagcaaatga tcttgcaacg
    74881 atcactccag ctaaaacata tactgctgca gattttccag acatgaacaa tcggacaatc
    74941 gatttaactg atttatcaga taccgggttt ttattggtaa atatcgatgc agaagtgtta
    75001 acgatgaata cgccacttca aatcattaat ccaaatgatc aagtagttgt atttaatgtc
    75061 atcaacagtt cttctgcatt gaacgtacag tcaccaatca aatacaatga tcgttcaaat
    75121 catgaaacag aagatttttc ggatgcgaat atctcttgga attttggaaa tgagatgact
    75181 gatttgacaa tcagtgctcc ttttcaagga acaatccttg cgcctaatgc tactatccgc
    75241 attactcaaa accaagacgg aacgattata ggaacaaatg tgattttaga tgcagctacc
    75301 aatcgttggg atcctaacga aatatttatc agcgacaatg gtacagatac tacagacaca
    75361 agcgacagta cagatacatc taccacaagt gatagctcag attcatca
//
LOCUS       DACGLI010000006        65552 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.006, whole genome shotgun sequence.
ACCESSION   DACGLI010000006 DACGLI010000000
VERSION     DACGLI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.006"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            204..722
                     /locus_tag="IXT22_000442"
     CDS             204..722
                     /locus_tag="IXT22_000442"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4861838.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            850..1533
                     /locus_tag="IXT22_000443"
     CDS             850..1533
                     /locus_tag="IXT22_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAQ4861839.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1842..1915
                     /locus_tag="IXT22_000444"
     tRNA            1842..1915
                     /locus_tag="IXT22_000444"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1876..1878,aa:Arg,seq:tct)
     gene            2074..2433
                     /locus_tag="IXT22_000445"
     CDS             2074..2433
                     /locus_tag="IXT22_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAQ4861840.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2556..4187
                     /locus_tag="IXT22_000446"
     CDS             2556..4187
                     /locus_tag="IXT22_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAQ4861841.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4249..4890)
                     /locus_tag="IXT22_000447"
     CDS             complement(4249..4890)
                     /locus_tag="IXT22_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4861842.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            5172..5480
                     /gene="rplU"
                     /locus_tag="IXT22_000448"
     CDS             5172..5480
                     /gene="rplU"
                     /locus_tag="IXT22_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAQ4861843.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5507..5851
                     /locus_tag="IXT22_000449"
     CDS             5507..5851
                     /locus_tag="IXT22_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAQ4861844.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5864..6157
                     /gene="rpmA"
                     /locus_tag="IXT22_000450"
     CDS             5864..6157
                     /gene="rpmA"
                     /locus_tag="IXT22_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAQ4861845.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6564..9398
                     /locus_tag="IXT22_000451"
     CDS             6564..9398
                     /locus_tag="IXT22_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4861846.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            9589..10080
                     /locus_tag="IXT22_000452"
     CDS             9589..10080
                     /locus_tag="IXT22_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAQ4861847.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10183..11172
                     /gene="manX"
                     /locus_tag="IXT22_000453"
     CDS             10183..11172
                     /gene="manX"
                     /locus_tag="IXT22_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAQ4861848.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11205..12008
                     /locus_tag="IXT22_000454"
     CDS             11205..12008
                     /locus_tag="IXT22_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAQ4861849.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12029..12943
                     /locus_tag="IXT22_000455"
     CDS             12029..12943
                     /locus_tag="IXT22_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAQ4861850.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13026..13400
                     /locus_tag="IXT22_000456"
     CDS             13026..13400
                     /locus_tag="IXT22_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAQ4861851.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13539..13784
                     /locus_tag="IXT22_000457"
     CDS             13539..13784
                     /locus_tag="IXT22_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4861852.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13956..15020
                     /locus_tag="IXT22_000458"
     CDS             13956..15020
                     /locus_tag="IXT22_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4861853.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15266..15691
                     /locus_tag="IXT22_000459"
     CDS             15266..15691
                     /locus_tag="IXT22_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4861854.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15684..16133
                     /gene="nusB"
                     /locus_tag="IXT22_000460"
     CDS             15684..16133
                     /gene="nusB"
                     /locus_tag="IXT22_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAQ4861855.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16230..17084
                     /locus_tag="IXT22_000461"
     CDS             16230..17084
                     /locus_tag="IXT22_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAQ4861856.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17085..18422
                     /locus_tag="IXT22_000462"
     CDS             17085..18422
                     /locus_tag="IXT22_000462"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAQ4861857.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18427..18651
                     /locus_tag="IXT22_000463"
     CDS             18427..18651
                     /locus_tag="IXT22_000463"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAQ4861858.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18653..19543
                     /locus_tag="IXT22_000464"
     CDS             18653..19543
                     /locus_tag="IXT22_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4861859.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19552..20370
                     /locus_tag="IXT22_000465"
     CDS             19552..20370
                     /locus_tag="IXT22_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAQ4861860.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20477..20926
                     /locus_tag="IXT22_000466"
     CDS             20477..20926
                     /locus_tag="IXT22_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4861861.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20944..22626
                     /gene="recN"
                     /locus_tag="IXT22_000467"
     CDS             20944..22626
                     /gene="recN"
                     /locus_tag="IXT22_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAQ4861862.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22681..22797)
                     /locus_tag="IXT22_000468"
     CDS             complement(22681..22797)
                     /locus_tag="IXT22_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAQ4861863.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22870..23826)
                     /locus_tag="IXT22_000469"
     CDS             complement(22870..23826)
                     /locus_tag="IXT22_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4861864.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23997..24365
                     /locus_tag="IXT22_000470"
     CDS             23997..24365
                     /locus_tag="IXT22_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAQ4861865.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24535..24966
                     /gene="mraZ"
                     /locus_tag="IXT22_000471"
     CDS             24535..24966
                     /gene="mraZ"
                     /locus_tag="IXT22_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAQ4861866.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24987..25946
                     /gene="rsmH"
                     /locus_tag="IXT22_000472"
     CDS             24987..25946
                     /gene="rsmH"
                     /locus_tag="IXT22_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAQ4861867.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLRQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25951..26352
                     /gene="ftsL"
                     /locus_tag="IXT22_000473"
     CDS             25951..26352
                     /gene="ftsL"
                     /locus_tag="IXT22_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4861868.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26353..28545
                     /locus_tag="IXT22_000474"
     CDS             26353..28545
                     /locus_tag="IXT22_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4861869.1"
                     /translation="MSLKNKIWRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28571..29533
                     /locus_tag="IXT22_000475"
     CDS             28571..29533
                     /locus_tag="IXT22_000475"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAQ4861870.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29547..30908
                     /locus_tag="IXT22_000476"
     CDS             29547..30908
                     /locus_tag="IXT22_000476"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAQ4861871.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30934..32022
                     /gene="murG"
                     /locus_tag="IXT22_000477"
     CDS             30934..32022
                     /gene="murG"
                     /locus_tag="IXT22_000477"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4861872.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            32037..33257
                     /locus_tag="IXT22_000478"
     CDS             32037..33257
                     /locus_tag="IXT22_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAQ4861873.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33413..34738
                     /gene="ftsA"
                     /locus_tag="IXT22_000479"
     CDS             33413..34738
                     /gene="ftsA"
                     /locus_tag="IXT22_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAQ4861874.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34761..36002
                     /gene="ftsZ"
                     /locus_tag="IXT22_000480"
     CDS             34761..36002
                     /gene="ftsZ"
                     /locus_tag="IXT22_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAQ4861875.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            36019..36696
                     /locus_tag="IXT22_000481"
     CDS             36019..36696
                     /locus_tag="IXT22_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAQ4861876.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36710..37309
                     /locus_tag="IXT22_000482"
     CDS             36710..37309
                     /locus_tag="IXT22_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAQ4861877.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37324..37611
                     /locus_tag="IXT22_000483"
     CDS             37324..37611
                     /locus_tag="IXT22_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAQ4861878.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37660..38442
                     /locus_tag="IXT22_000484"
     CDS             37660..38442
                     /locus_tag="IXT22_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAQ4861879.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38463..39170
                     /locus_tag="IXT22_000485"
     CDS             38463..39170
                     /locus_tag="IXT22_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAQ4861880.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39432..42230
                     /gene="ileS"
                     /locus_tag="IXT22_000486"
     CDS             39432..42230
                     /gene="ileS"
                     /locus_tag="IXT22_000486"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAQ4861881.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42279..43805)
                     /locus_tag="IXT22_000487"
     CDS             complement(42279..43805)
                     /locus_tag="IXT22_000487"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAQ4861882.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43820..44467)
                     /locus_tag="IXT22_000488"
     CDS             complement(43820..44467)
                     /locus_tag="IXT22_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAQ4861883.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44651..44980)
                     /locus_tag="IXT22_000489"
     CDS             complement(44651..44980)
                     /locus_tag="IXT22_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAQ4861884.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45157..45885
                     /gene="sfsA"
                     /locus_tag="IXT22_000490"
     CDS             45157..45885
                     /gene="sfsA"
                     /locus_tag="IXT22_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAQ4861885.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45901..46914
                     /locus_tag="IXT22_000491"
     CDS             45901..46914
                     /locus_tag="IXT22_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4861886.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFYVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46914..48191
                     /locus_tag="IXT22_000492"
     CDS             46914..48191
                     /locus_tag="IXT22_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4861887.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKKKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48254..50956
                     /locus_tag="IXT22_000493"
     CDS             48254..50956
                     /locus_tag="IXT22_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4861888.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKKEFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51108..51425
                     /locus_tag="IXT22_000494"
     CDS             51108..51425
                     /locus_tag="IXT22_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4861889.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51455..51775
                     /locus_tag="IXT22_000495"
     CDS             51455..51775
                     /locus_tag="IXT22_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4861890.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51883..53343
                     /locus_tag="IXT22_000496"
     CDS             51883..53343
                     /locus_tag="IXT22_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4861891.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53411..53632
                     /locus_tag="IXT22_000497"
     CDS             53411..53632
                     /locus_tag="IXT22_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861892.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53663..53845
                     /locus_tag="IXT22_000498"
     CDS             53663..53845
                     /locus_tag="IXT22_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAQ4861893.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53845..54258
                     /locus_tag="IXT22_000499"
     CDS             53845..54258
                     /locus_tag="IXT22_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAQ4861894.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54381..55562
                     /locus_tag="IXT22_000500"
     CDS             54381..55562
                     /locus_tag="IXT22_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4861895.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            55951..56024
                     /locus_tag="IXT22_000501"
     tRNA            55951..56024
                     /locus_tag="IXT22_000501"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55985..55987,aa:Arg,seq:cct)
     gene            complement(56093..57232)
                     /locus_tag="IXT22_000502"
     CDS             complement(56093..57232)
                     /locus_tag="IXT22_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4861896.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57531..58166)
                     /locus_tag="IXT22_000503"
     CDS             complement(57531..58166)
                     /locus_tag="IXT22_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861897.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58279..58914)
                     /locus_tag="IXT22_000504"
     CDS             complement(58279..58914)
                     /locus_tag="IXT22_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAQ4861898.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58948..59409)
                     /locus_tag="IXT22_000505"
     CDS             complement(58948..59409)
                     /locus_tag="IXT22_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAQ4861899.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59539..59970)
                     /locus_tag="IXT22_000506"
     CDS             complement(59539..59970)
                     /locus_tag="IXT22_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4861900.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59988..60308)
                     /locus_tag="IXT22_000507"
     CDS             complement(59988..60308)
                     /locus_tag="IXT22_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861901.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60607..61383
                     /locus_tag="IXT22_000508"
     CDS             60607..61383
                     /locus_tag="IXT22_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAQ4861902.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61398..61601
                     /locus_tag="IXT22_000509"
     CDS             61398..61601
                     /locus_tag="IXT22_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861903.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61617..61937
                     /locus_tag="IXT22_000510"
     CDS             61617..61937
                     /locus_tag="IXT22_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAQ4861904.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRR"
     gene            complement(62119..62901)
                     /locus_tag="IXT22_000511"
     CDS             complement(62119..62901)
                     /locus_tag="IXT22_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861905.1"
                     /translation="MDISDTPYYQKLIASSKLIGETIAPSLDVVNAMQPAIEQAKKLI
                     AIQDTFIASQAILNDSLIQIVEKRNKSIANMIPPSLFAIQKQLESPSFNIAKKMAATM
                     PKPYFSDISKITEKFAVDMSKYDFRIGVATQELEKAFSSEPEVSTKNLLFKDTSNPSD
                     EFEAKFFDILNEQRKVLDDSIKLFEEINTAKNKDITNEPSEKQQASPAFYKDKMWYLE
                     QTGAALIGLVVTEIVNITIGVDPNNTISLALFLRYLLQFLIN"
     gene            62967..63659
                     /locus_tag="IXT22_000512"
     CDS             62967..63659
                     /locus_tag="IXT22_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4861906.1"
                     /translation="MLKNKEAVTTSLQVAETFRKEHRAVLKAIDDLKDGLAQKYADLF
                     WEDVYIHPQNKQAYRIVYMNRDGFTLAVLGFNNTQKVLEFKLKYIEAFNEMEKAIRKN
                     TAFDTIEDMMIYQLEEMKDVKKDVSMLKNTMRISGQQEFEIKQKGNTKVMEVLGGKES
                     RAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEIDQL
                     NRQQRLFGDENE"
     gene            63837..64178
                     /locus_tag="IXT22_000513"
     CDS             63837..64178
                     /locus_tag="IXT22_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861907.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            64171..64842
                     /locus_tag="IXT22_000514"
     CDS             64171..64842
                     /locus_tag="IXT22_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4861908.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64848..65534
                     /locus_tag="IXT22_000515"
     CDS             64848..65534
                     /locus_tag="IXT22_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861909.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
BASE COUNT        21746 a        10985 c        13700 g        19121 t
ORIGIN      
        1 tcctttctaa aacttgtaat gttagggtaa acgtttttta aactaacgtc aattatttat
       61 aataaaaaat gagataaaga tgaggaaata gaattagaaa catataatta ttaaagggaa
      121 acatttttac agctataatt tgaaaaaaat ttatcgttat tatatgatta agaaggattg
      181 aataaagaaa gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta
      241 taacgttgat tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg
      301 gtttgactcc ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc
      361 tgatatatgt acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt
      421 atgaaaattc aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg
      481 aagattttta tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga
      541 gaaatattat cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa
      601 cggcatttgc atggattcag gggttattct ttacgattgc tttttgccta acaggaatca
      661 cagcatggaa tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt
      721 aagaatgtta aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca
      781 cgagaaaaca ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg
      841 aggagtagta tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat
      901 tttatgcgta cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct
      961 catgtagcag aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt
     1021 ggacagcttc agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt
     1081 gtcatggcca cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc
     1141 atgatcgaga aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg
     1201 cttgaaggtc aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt
     1261 atggatagtg caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga
     1321 aaaggtggcg ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat
     1381 gaagagattc cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt
     1441 gtgatggatc atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta
     1501 atgacaaagg aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa
     1561 tcgattgaat cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa
     1621 ttaaaggata caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt
     1681 ttcaattgat aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag
     1741 tagttgggcc aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag
     1801 caatttaatt atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg
     1861 atagagcatc cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa
     1921 aaaccgttag aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt
     1981 gttttcaaag gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa
     2041 aaaataaaac tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg
     2101 actctagttg caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct
     2161 gacacgacaa gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa
     2221 acattgttta agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga
     2281 gcttatcttt cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt
     2341 gttgcattat atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta
     2401 gctctgttgg cattgctttc tattttctta taaatataga aaaaataaga atttatctaa
     2461 caggaaactt tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt
     2521 attttagaaa atttcatgaa aaaggagtta gataggtgtt caaaaattat gtttcctcac
     2581 taaaaaaaga attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga
     2641 tcacagtagc tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg
     2701 atgcggccgc aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag
     2761 gcggttttta tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg
     2821 cggcaacaaa gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac
     2881 ttgcagcagg acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta
     2941 cggggtttac ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg
     3001 gtgttcactc ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat
     3061 ttccgataaa cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct
     3121 atccaaaaaa atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag
     3181 cagttatgct attgttccat ttaccagtag caactgtggg taagattcca caaacattga
     3241 tcagtagtaa tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag
     3301 ttccagctat tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg
     3361 ctggccgaat ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg
     3421 gaaatctgtt gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa
     3481 gcgtggccat caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct
     3541 tactgctctc catgcttgtt tttgcgccag tgatgtcaca gattccaatg ccagcacttg
     3601 caggtgtttt gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat
     3661 ttactaataa atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta
     3721 tctttgattt aagtattgct atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg
     3781 tcaaaagcgc tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc
     3841 cagaaacgga aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta
     3901 tgtcttcaga aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt
     3961 tctccatgcg aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc
     4021 aagaaaaagc agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag
     4081 aaaaacaact ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc
     4141 atgcgttgac agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag
     4201 aacagacaag actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg
     4261 taaaagtgaa gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta
     4321 gaaaatagct gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta
     4381 ggcatccttt tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt
     4441 ggtaaccgta tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat
     4501 taattttggc tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc
     4561 ggaacgagta ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat
     4621 ccgatgagtc acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg
     4681 tgttaagcca gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg
     4741 aacatgcgta tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg
     4801 aagaggtcct tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc
     4861 ttcttgtatc agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag
     4921 aataaaagaa acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga
     4981 agtattgctt gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct
     5041 gttctggtaa gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa
     5101 gtaataagca cagcatatgc tgtcacttcg gatggcgagt ctaagtatat cagaaggagg
     5161 tgctttatag catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg
     5221 gacaagcaat ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg
     5281 aagttatctt agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa
     5341 ctgttgaagg tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca
     5401 aacctaaaaa acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta
     5461 tcgacgcgat caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac
     5521 atttaagcga aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc
     5581 tggtccttat ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt
     5641 caacgggatt gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg
     5701 cggttatctt tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga
     5761 gattctatta gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata
     5821 tatccaaatt aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa
     5881 tctacaatta tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga
     5941 atcaaaacgt ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct
     6001 ttaccgtcaa cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga
     6061 cactttattt gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa
     6121 acaagtgtct gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt
     6181 tgtgacaaga cttttgtcac agcctttttt gtttataaaa ataaaagttg tagtggaggc
     6241 tacgaagttt actttgtctt tttacactta atattttttt gccaatttgg aatcaggatg
     6301 ttttgataac tatcgttttc aattgatgga agctatattg tttgctatca gtgaaataat
     6361 tatatggtaa acagtgttct ttttcttgtt tccattataa aaatcgtatc gggatttttc
     6421 gttcttttaa attgaacatt tctatctatc cgcgtgttat caacaaaaca aaatcaggta
     6481 aatagttgac gaaacagaaa taaatacata gtattatgtt ttgaagccta agtacaatag
     6541 tctatagaaa aggagcgata ccattggcaa aacgcattga ccgaatttat atgtatgtca
     6601 aagaaaaaac cgctcattta acaaaggcag aatatgatca aggagtaaca acacaggaaa
     6661 ttgctgaagt gttagggatt cagcgaacaa atagcagtaa agatctgaat cagctagtgc
     6721 gcgaaggaaa actgataaag acagacggac gaccagtacg ttacatatat caaacactcg
     6781 ttacgcacgt aaagccagtt acaaaacatg tagtcagtta caaagaaacg ccggtctctg
     6841 aagaaaaaaa tacactccaa atagatacta aggatatctt tgcaaaaatc attggagcta
     6901 acggcagcat gaaaaattca gtggaacagg caaaagctgc gattttgtat ccgccaagag
     6961 gattaaattg tttgattaca ggacctaccg gatcaggaaa gacttatttt gcacacgcga
     7021 tgtatcattt tgcaaaagcg catcatgtaa tagatgagga aacggaactg attgttttca
     7081 attgtgctga ttatgccaat aaccctgagc ttttgatgag tcatttattt gggtacgcaa
     7141 aaggtgcttt tacaggcgca gatgaagaaa aaatggggat tatcgatcaa gcggatggcg
     7201 gtatgctgtt tttggatgag attcaccggt tgccgcctga aggtcaagaa atgatctttt
     7261 actttatgga tcatggaact tacagtcgtc ttggggaaac aacgaaatcc catgaagcaa
     7321 atgtacggat cgtaggtgcg accacagaag acccaggttc ttctctatta gaaacttttg
     7381 ttcggcgtat cccaatcaat atcaaacttc cggcttttga aaaacgtcct gcaaatgaga
     7441 aagtcgattt agtaaaaatc atgattgccc acgaagcaaa ccgcacgcag cgaaagattt
     7501 ctttgacaga agatgtagca aaagcattga tcggcagtgt gacctatgga aatataggac
     7561 aattgaagtc aaatatccag ttagtatgtg cacgaggatt tctaaatcat atgcaatcac
     7621 ccgaaatctc gatcacaatc gatgatttga cagaagggat tcgtagcgga ttgattcaat
     7681 tagcaagcaa ccgcagtgca atggcagagc tttctaaaat attggagcca aagataactg
     7741 tagcaccaaa tgatacgatc atgaaaatcc aatcggactc ctatgagtta ccttataatc
     7801 tatatgatat catcggagat aaagcagctt tactgaagtc ggatggtttg gatcaagaag
     7861 caatcaatca tttcatttct acagatatca acatccatct gaagtctttc tataaagacc
     7921 atggtttttc ttttaatgca gacagcaaat tagcagaatt tgtagatccg aaaatcatag
     7981 aagtgaccaa tcagatttat gtaatggtca aaagatcttt accatatgag tttcagcaaa
     8041 actttattta tgctatgagc ttgcatatca gttctttttt gaaaaaaatc aacttaggag
     8101 aagaacggca tacgaatgat aacatccgtg agatggcttt tgattttcca gatgaatatg
     8161 ctgttgcgaa agaagtgcgt agttatatcg aaacgtattt tcaagtggag attccagaaa
     8221 gtgaagacta ttacttgacc gttctactcg tctcgttacg ggcaaatcaa gcaagcggca
     8281 gaatcggtgt agtcgttgca gctcacggaa acagcacagc aagcagtatg gtccaagttg
     8341 tccaacagtt gttagatgca gagaacgtac gagcagtaga catgcctttg gatatggatc
     8401 cgaaaacagc attggaccga attgaacgca atgtacaaga agtagatgaa ggaagcgggg
     8461 tcatactctt agtagatatg gggtcccttg cgtcgtttaa ttcgcaaatt caaagagaca
     8521 ctggaattcc agtacgtact gttgatatgg taacaacttc tctagttttg gaaactgtac
     8581 gaaaggtctc agtattaggg acagatctag atatgttgca tgaatcattg aaaaattttc
     8641 gaggttacgc agaaatatct tctgtagaat ctgttcagga agcaaaacct attcataaga
     8701 aaaaagctgt tttggctatc tgcgcatctg gcgaaggtac agcacaaaga atcaaagaat
     8761 tgatcgaacg agcggtaaac aagcgtcaag aaacagaatt agaagttcta gctttgtcga
     8821 ttgtggaagt gaaagaagaa ctgccagtta tccaaaaaga atatcagatc atagctacta
     8881 ctgggattac tgatttgaat atccaagccc catttattcc tttagaacgt tttattgatc
     8941 aaaatatcga agtcattttg gatcagttgc tgatggaatc agaattggag gaaactgaat
     9001 tcatctccct agatgaagag tcagctaaaa atacgtgtgt tgagtttatc tctgataact
     9061 tcatctttat taatggtagt aagttaatcg atccaatgtg gcaattttct acacaaatct
     9121 ctcagacgac gggaatcggc gatgaagaat atggattcaa aatcaaccta gtgatgcaca
     9181 cagcaggaat gatcgaacgt attattcgga atgaaccatt gactgtggaa gaaaacgaat
     9241 tgacaaatac aacgaatgat cctctttata gccaattggc agcctcagtt gttctgttgg
     9301 aagatcagat aaaagtaaaa gtgccgatag aagaaatgta ttatctgcta cgtctagtcc
     9361 ataatcagtt agataaaaaa gaatacactg tgccatgaat acacaaaaac gatacacttt
     9421 tatagtgtat cgtttttgtg tattggttaa gaatccttta aattcaatta gtgtatcgta
     9481 aaaaagttgg cacgcttttt gcttatagta gtgtgtgcta ggaggtggtt gttcacacag
     9541 aaatgatagg ggtttctgtg aagtagtgag gaagaaggag ttttgcagat ggatattcga
     9601 ttggcacgta tagatgatcg tttaatccac gggcaagtcg caacagtttg gtcgaagcaa
     9661 acaggtgttg aacgtatcat tgtgatcagc gatgtagtcg ctcaagataa attgagaaag
     9721 tttctactaa aagaagctgc accgccgggg atcacagcaa atgtaataac cgtgcagaaa
     9781 atgattcaaa tctatcatag tggattatta tcacgagcaa aagtgatgct tttattcacc
     9841 aatccccaag atgttgaagc ggttgtccgc tgcggtgtac agttgaagtc gttgaatatc
     9901 ggcggtatga gttttactga aggcaaatca atgattacca attttgtttc agtaaatcaa
     9961 caagatattg attcctttcg ttacttgaac agtcaagaag tggagttaga gattcgaaaa
    10021 gtacctgctg acaggaaaat ccttttgatg gaactactag cgaaaatcaa aaaggtgtag
    10081 caagaatggt tgttggaaaa ggtcaaataa ttctgttgta atggttagca attattaata
    10141 tttttgaatt tgttacaaca aaagtaaata ggaggtataa atatggtagg gattatccta
    10201 gcaagtcatg gacaatttgc tgaaggaatc ttacaatccg gttcaatgat ctttggcgaa
    10261 caagaaaacg tcaaagccgt gattttgaaa ccaagtgaag gtccagatga cttgagagcc
    10321 aaattggaag aagcggttgc ttcttttgat aatcaagacg aagtgttatt cttagttgat
    10381 ttatggggcg gaacaccgtt caatcaatca aacacattat tcgaagagca caaagataaa
    10441 tgggcaatcg tcagcggttt gaatttacca atgttgattg aagcctacgc atcacgcttt
    10501 tcaatggaat ctgctcatga aattgcagca cacatcattg aaacagcaaa agacggtgta
    10561 aaagtaaaac cggaagaatt agaaccggca gaagcaccga aagcagcagt tgaagacgca
    10621 caacctaaag gagcacttcc agaaggaact gtggtcggag acggaaaaat caaatatgta
    10681 ttagcacgtg ttgactcacg tctgttacat ggacaagttg cgacagcttg gacaaaagca
    10741 gtgcaaccaa accgtattat cgttgtttca gatgcagtat caaaggatga tctgcgtaag
    10801 agactaatcg aacaagctgc tcctccaggt gtaaaagcaa atgttattcc tattagcaaa
    10861 atgatcgaag tagcaaaaga ccctcgtttt ggaaatacca aagcattgct tttatttgaa
    10921 aatcctgaag acgtattgac agctgttgaa ggtggcgtag acatcaaaga attaaatgtt
    10981 gggtcaatgg cgcattcggt cggtaaagtc gttgtaagta aagtattgtc tatgggacaa
    11041 gaagacgttg aagcgtttga gaagcttgaa caaaaaggtg tgaaattcga tgtacgtaaa
    11101 gtacctaatg attcacgcga taacatggat gatattttga aaaaagcaaa agctgaatta
    11161 gcaaaagcgt aataaataat attaaaattt ataggaggct tatcatgtct attatttcaa
    11221 taattttagt cgtattagtt gcctttctag ctggtatgga aggtattctt gatgaatttc
    11281 aatttcatca accactagtg gcatgtacat tgatcggttt agttaccggt aacctcgaag
    11341 ctggtatcgt acttggcggt acgcttcaga tgatcgcttt aggttgggca aatatcggtg
    11401 ccgctgtagc accagatgct gcattagcat cagtagcatc agcaattatt ttagttttag
    11461 gtggacaagg tgttaaaggt gttccttctg cgatcgcgat tgccgttcct ttggctgttg
    11521 cagggttgtt cttaacaatg atcgtacgta caatcgctgt tccaatcgtt catttgatgg
    11581 atgcggctgc tgaagaagga aacatccgta aggttgaaat gtggcacatc attgctgtat
    11641 gtttacaagg ggttcgtatc gcggtcccag cagcagcgtt gctatttatc ccagcacaaa
    11701 ctgtgcaatc attccttgaa tcaatgccag catggttaac agatggtatg gctatcggtg
    11761 ggggaatggt cgtagctgta ggttacgctt tggtaatcaa catgatggct acaaaagaag
    11821 tatggccatt cttcgttatt ggtttcgttg tagctgcaat ttctcaatta acattgattg
    11881 ctctaggtgc tttaggtgtt gcattagctc ttatttactt gaacctttct aaaatgggtg
    11941 gttcatcaaa taatggaggc ggaagcaact ctggtgaccc tttaggcgac attttgaatg
    12001 actattaatc ttgaaggagg aaaataaaat ggcagaagaa aaaatcaaat tatcaaaaaa
    12061 agatcgttta gctgttgcgt ggcgctctac cttcattcaa ggttcatgga actacgaacg
    12121 tatgcaaaac ggtggctggg cattttctat gattccagca atcaaaaaat tatacaaaac
    12181 aaaagaagaa cgttctgcag cattaaaacg tcacttggaa ttctttaata cacacccata
    12241 cattgcttct ccaattttag gggttacatt ggctctggaa gaagaacgtg cgaatggcgc
    12301 gcctgttgat gatgtagcga ttcaaggggt taaagtaggt atgatgggtc ctttagctgg
    12361 tgttggtgac ccagtgttct ggtttacagt acgtccaatg ctaggtgcac taggtgcttc
    12421 attagctatg ggaggaaata tccttggacc aatcatcttc ttcttaggtt ggaacattat
    12481 tcgttgggca ttcatgtggt atacacaaga atttggctac aaagctggtt ctaaaattac
    12541 tgatgacctt tctggcggat tgttacaaga cgtaacaaaa ggtgcttcaa ttttagggat
    12601 gttcgtatta gctgcccttg tacaaagatg ggtatcaatc aaattcttac cagttgtatc
    12661 aactgtaaaa ttagataaag gtgcttacat cgaatgggat aaattgcctt caggtggtga
    12721 aggaatcaag agtgcatttg aacaagttaa taatggctta gccctttctc ctgaaaaggt
    12781 aacaacatta caagacaact tagaccaatt gattcctggt ttagctgcat taggattaac
    12841 attgttatgt atgtggttgc ttaagaaaaa ggtttctcca atcgttatca tccttggttt
    12901 attcgtagtc ggtgttgttg gacacgtcat cggactttta taatccataa aaatatagct
    12961 cgggcgttgt cccgagcttt ttttatatag tatactgttc ataaacaaat atctggaggg
    13021 agaaaatggt tcaatcaatc aatacaaaag tagacttggt aattgatgct acttcgttta
    13081 cgggtctgac agattacggg caaatcatga taggtgataa tggttttgag ttttaccatg
    13141 cgcgagatag acgcaaatat atccaaattc catgggaaga agtggattat gtactagcat
    13201 cagtcatgct aaagggaaaa tggattcctc gatatgccat tcaaacgaaa aaaaatggta
    13261 catacacatt ttcttccaaa gaacctaaaa aagtgcttcg tgcgatcaga gaatatgtag
    13321 atgaagatag aatggtacaa tcattgagtt tctttgatgt agtgaaacgt ggtattcgta
    13381 gtatgtttaa acgcaagtaa aaaataaaga aaacttctaa gaggaggttt tctttatttt
    13441 tttactttgc agaagaaaat atgaaatagc aaaaccaatt atttgtcccc tttaaatccc
    13501 atatgctaaa attgattagc aaagaaggag gttatattat gagttggtta tggacattga
    13561 ttgttggagc cgtgatcgga gcaattgcag gtgcgatcac cagtaaagga aattcgatgg
    13621 gctgtgtaac gaatatcatt gctggactag tcggttcaag tattggacaa gcgattttcg
    13681 gcgaatgggg accaaaagct gcaggtatgg cacttattcc atctatttta ggcgcagtga
    13741 ttttggtagc agttgtctca tttttctttg gaaaacgatc ataagttttt acaaaatagt
    13801 aaactaaaag gagttgcagc gagactgtga ctcctttttg gctttattta tttaaaataa
    13861 aaagaagttt tccggaaatt tttatttaac tgtcgtgtac gaagaaaagt ttgctataat
    13921 ggaaaaaagc gtgcaaagaa agagggagtt tcattatgat gctacgtgta gaaaaattgc
    13981 gcaaaaaaat gcaagaagaa aatttggatt catttttggt taccagtccg tacaatcttc
    14041 gttacttaac gaactttaca ggtacgacag gattagctgt tattactttg gaaaaagcat
    14101 tttttattac tgattttcgt tataccgagc aggcggcagc gcaggctcaa gggtttgaaa
    14161 ttattaaaaa tgtcggacct atttttgatg aggtagcaaa cttagtacgc aaagaagaac
    14221 tgcactcatt agcttttgag gaaacaacag tctcattttt agaatattcg gttttagaag
    14281 aaatcatcga tgcggaatta gtacctgttt cacagatgat cgaagaactc agagaagtga
    14341 aagatgaaga agaaatcgct attatcgaaa aagcatgtca tattgcggat atggcatatg
    14401 atcacatcct gaaaatgatc caaccgggca tgactgagat tgaagtcgca aatcaactag
    14461 acttttatat gcgttctctt ggcgcttcag gtgtttcttt tgatacgatc gttgctagcg
    14521 gattgcgttc ggctatgccg catggtgtag caagcaaaaa aatcatcgaa caaggtgact
    14581 tgatcacatt ggactttggt tgctattacg aagggtacgt ttccgatatg acacgtacat
    14641 tcgctattgg tgatcctggg gaaaaattaa aagaaattta tcaaatagtc ttagatgctc
    14701 aattagcagt tattgatgct gcaaaaccag gaatgactgg tgtccaatta gatgcagttg
    14761 ctagagatta tatttcaaaa catggttacg gggaagcatt tggacattct acaggacatg
    14821 ggatcggttt agagatccac gaaggaccaa acgtttcttc tcgtgcagaa aagcaatttg
    14881 taccaggaaa tgtgatcact gatgaaccag ggatctactt accaggaatc ggtggagtac
    14941 gtattgagga tgacttgttg atcacagaag atggaaatcg tgtgttgact cgttcaccaa
    15001 aagaattgat catcttatag tttcatcaat agaagaagta agcgtaaaaa tcagtgttca
    15061 cagactttgt tatagaaaat cactcgattt aatgatacac tatagaagaa cttttaagct
    15121 gtaagagata ataaagttgg gtgttttctc caattcatag cagtttgcag ctgatcggcg
    15181 gcagttttct taccacgtga tcactatgcc gcatcataga gaattcggat gtatctcgtg
    15241 cttaggcaaa gggaggaata aataaatggc agatgaaaaa aatttgattt taaacgcaaa
    15301 ccaagattta ggagagatcg tgatcgctcc tgaagtcatc gaagtaatta tcgggattgc
    15361 agcttctaaa gtagaaggcg tatacggaat gcgcggaact tttgccagca atgtcactga
    15421 attattagga cgtgcagctc acggaaaagg tgtttactta gcaaacgagg aagatggctt
    15481 gaaagtagat ctttactgtt atctagaata tggtgtttca gttcctaaag tagcaatgga
    15541 aatgcaggaa cgggtcagcc agcaagtcct tttcatgacg gatatcgatt tatctgaagt
    15601 caatatccat gtagtagctg ttgttcctga aaaattagaa caaccaacaa tcgaagaact
    15661 ttttgaagac gaagaggaag agaatgaata aagaattatc aagacacgag attcgggaaa
    15721 tggcattgca ggctttattt ccattagact tcaatgcaga cctaacaaaa gaagatgcga
    15781 ttttcaacgc aatcgaatta gaccaccgcg acatgatcaa cgaagatgaa tcagagtttg
    15841 ttcctgttta tcttgatacg ctagttggcg gtgtctgtgc aaaaaaagat gaattggata
    15901 aagtgattga aaaacattta aaaaacaatt ggcacatcaa tcggatctca aaaatggatt
    15961 tggtgatctt gcgtatcgcg atttttgaaa tgacttatgt gacagatgta ccagcggctg
    16021 ttgctttaaa tgaagcaatc gagttggcaa aaacatttag tgatgaccgt tcacgtaaat
    16081 tcgtcaacgg tgttttatcc aatgtattga aagaattaga agctggggcg taagtcctag
    16141 cttttttcta tgaatcatca taaacctgtt ataaatcggg aaaattctat ggtagaatga
    16201 aaacacaaaa aatatctggg agtggttaga tggcagaatt gattaacgga aaagaattag
    16261 ctgaaaaaat gcaggcagag attgctgaaa aaatccaaaa attgaaagat aatggtatcc
    16321 atcccggatt agtcgtttta ttggtagggg aaaatccagc cagccaaatc tatgtaagaa
    16381 ataaagaacg tgtagcaaaa gaaatcggaa tccattcatt ggtagagcgt tatcctgaga
    16441 cgatttctga agacgaacta cttgcagaaa ttgaaaaata caatcaagat cctagttttc
    16501 atggtatatt ggtccaatta ccattgccaa agcatataga tgaagaaaag atcctgttag
    16561 ctatccgccc tgaaaaagac gtagacggtt ttcatccgat gaatttaggc agactccttg
    16621 cgggtaaacc ggacaagatt ccttgtactc catacggcat catgaaaatg tttgaagctt
    16681 attctatcga tccggcgggt aaacgagcag tagttatcgg acgaagcaat atcgtcggta
    16741 aaccgatggc tcagctactc ttgatggcag atgcaactgt tactgttgct cattctaaaa
    16801 ccgaaaatct ggctgaactg gcacaagaag cagatatttt agtcgtagca ataggacgtg
    16861 gacattttgt cacaaaagaa ttcgtaaaac caggtgctgt agtgatagat gtagggatga
    16921 atcgtgatgc taacggtaag ctgatcggtg atgtgaaatt tgatgaagtg gagcctattg
    16981 caggctggat cactcctgtg ccaaagggtg tagggccaat gactatcacg atgctgatgt
    17041 atcaaaccgt aaaatctgcc gaagcttttg gagcaggtga atagatggca caagaatatt
    17101 taactgtcac tacattaacg aagtatttga aaagaaaatt tgatgccgat ccttatttag
    17161 aacgcgtata tttaacaggc gaaatatcga atttccgttt acgtgccaat gcccatcaat
    17221 atttcagctt aaaagatgac catgcaaaaa tatctgctat tatgttcaaa ggagcattcc
    17281 aaaaattacg attccagcca aaagaaggaa tgaaagtcct tgtcgttggg cgtatttcat
    17341 tatatgaagc gggaggttct tatcaaatct atgtagagca catggagcct gatggaatag
    17401 gtgctttata tcaagaattg gaagaacgaa aagaaaagct gatgaaggaa ggcctttttc
    17461 aagggcctaa aaaaatgctg ccacgtttcc caaagcgaat cgcggtcctt accagtccaa
    17521 gcggagcggt tatccgcgat atcatcacga cggtgaaaag aagatatcca attgtccaat
    17581 tggttttgtt cccaacagtt gtacaaggaa accaagcagc ggacaatgtt gtcaggaata
    17641 tccagagagt agaagagatg ggcaatttcg atacaatgat catcggtcgt gggggtggtt
    17701 cgattgagga tttatggccg tttaatgaag agcgggttgc tcgggcgatt tatcaagcta
    17761 atacgccggt gatttcatct gtaggacatg aaacagatac cacgatcgct gatttagtag
    17821 cagatgttcg ggctgccact ccaacagcag ctgcagaatt agctgttcct gttttgtcag
    17881 aagagttgat gcgcattcaa gaacggcaag ctagattgca gcaggcgttt gtacgccaga
    17941 tccagcgcaa acaagaacgg ttcgagcgtg ctcgacgttc ctatgtattt cggcagcctg
    18001 aaagattgta tgaaggtcag accatcaaat tagaccagtt gaaacagcga ttatatcaag
    18061 ctacacagca aatttatcat gcgaaagaaa aacaaacgat cgcattaagc caccaattgg
    18121 aacaagtggc tccgctttat cgagttaaag cagctcgcca agaaactgct tatctagaaa
    18181 aacgcttaga agagaaaatc caacaatata tgaaacaaca gcagcagcgt tttgctcaag
    18241 ctgttcaatc tcttgatttg ttgagtccat tgaaaatcat gggaagaggc tacagctata
    18301 cgacgttaaa tgatcaagta gtaaaaagtg tcaccgagat tcatcaaggg gatttgctga
    18361 cgatccatta tcaagatgga atcgttaaag gacaagtaca agagatagac aaaggagaat
    18421 aaaaatatgg aaaatccaac ttttgaagag tcactgcaag aattagaaaa aattgtcatg
    18481 cagttagaac aaggagacgt tccattagaa tcagctctag attcgtttaa acgaggaatg
    18541 gaattaagca aacattgcca agatacatta gctaaagcag aagagacctt gacgaaaatg
    18601 atgacagaat caaatgaaga agttgatttt gacggaaacg aggaaagctg agatgagatt
    18661 aactgacttt tcagctattc atctacctgc tgtagaaaaa gaaatcttgt cttttttaga
    18721 tgagcataca acggatagag gactctatga tgcgatgagt tattcagtga aagcaggcgg
    18781 gaaaagaata cgtcccttat tacttttaac ggccgttgct tcctttgatg agcctattga
    18841 tgttcccgtc tatcaagtag cagctgcttt agaaatggtg catacgtatt ccttgatcca
    18901 cgatgatttg cctgcgatgg acaatgatga tcttcgtaga ggaaaaccta ccaatcataa
    18961 agtattcggc gaagcattag ctatattggc cggagatggt ttgcttacag gagcattcca
    19021 gctaatcagt atggcacact taggtaattc tcctaagctt ctgctgcttc agcaattagc
    19081 tgtttgtgcg ggatcacaag gtatggttgc tgggcaagct gcagatatcg agggcgaatc
    19141 gaaaaagctt tctttagaag aattagcatt tattcatgaa agaaagacag ggcatttgat
    19201 tcgttatgcc ttgctggctg gtggcatatt agcgaagcaa cctgaagaaa tcttattgct
    19261 acttcaacga ttagccgaac atttaggttt agcttttcag ataagagatg atctactcga
    19321 tgtgattggt acaacgaaaa cattagggaa aacagctggt aaagatgaac gtatggaaaa
    19381 aaatacttac ccgcgtttat taggcctaga aaagacacgt gaggcgttgg agattgagct
    19441 gttatccgcc aacaagatca tagacaaatt agaagaggac gttttttctt ttgatggcgg
    19501 gctgatgcgc cagatgatca agcaatttga tgtggagaaa tgagggaaag aatggaaaaa
    19561 gaacgcgtag atgtattagc ggtcaaacaa ggattatttg aaacaagaga acaagccaaa
    19621 cgttcagtga tggctggttt gatttacaac gaaaaaaacg agcggtttga taaaccggga
    19681 gaaaaaattc cagtgagtag tgaattaaga gtcaaaggta aaaaacttcc ttatgtttct
    19741 cgagggggat taaaattaga aaaagcactc aaagcatttg atctatctgt tgaaggaaaa
    19801 acattgttag atattggtgc atccactggc ggatttactg atgcagcttt gcaaaatggc
    19861 gcaaaaatga gttatgcttt agacgttggc tacaatcagc tagcttggaa aataagacaa
    19921 gatcctagag tcgtcgtaat ggaaagagtg aattttcgtt atgcaaaacc cgaagacttt
    19981 accttaggaa ttccagaagt tgctgttatc gatgtttctt ttatttcact aaaactgatg
    20041 ctgcctccat tacatgctat tttaaaagaa gagggagaag tgattgcttt aatcaaaccc
    20101 caattcgaag caggcagaga agctgtaggg aaaaacggaa ttgttcgtga ccctcagacc
    20161 catcaaaaag ttttagaaga cattttgtca tttgcggcac aaggtggata tgatgtgctg
    20221 gaattaagtt attctccgat cacgggggga gaaggaaata tcgagttctt ggctcacttg
    20281 aggaaagtac ccgaaagcgg aacaatcaat tcagctatta atatggcaga agtggtttca
    20341 aatgcacacg aacagtttga ccataaataa attgtaactg tgaaaatcaa gtgagaagta
    20401 tgcggattct tctttattat accaaggaaa taagctatca ttgattaaga agaatatgct
    20461 aaggagcgaa gacgtaatga gaaaaaaaga tcggcatcgt ttgattactc gattgttgag
    20521 tgagcaagat atccgaaagc aggaagaatt tgttgaaatc ctgaaaagca aaggaatatc
    20581 tgttactcaa gctacgattt ccagagatat aaaggaactg aaactgatca aggtaccggc
    20641 ttcagatggc ggctaccgtt atagcatacc agctgaaaca aacgaagatg taaatactaa
    20701 attggaaaaa ctattaaaag acgctttcgt ggcagttgac caaatggaaa aatttgttat
    20761 tttgaaaaca ttgccgggaa atgcttcggc agcagcaaat ttgattgata aacgttacaa
    20821 gaaagaatta ttttcgatta tcaatgatga cgataatgtt ttgatgatta cacgaactga
    20881 agaccaggca gttttattga agaaagactt cctgcattac ctttaagttg aggagcgaat
    20941 gtgatgctac aagaaatcag tattactaac tttgcgatta ttccggaatt gcggctttct
    21001 tttcacgaag gaatgaccgc gctgaccgga gagactggtg cgggtaaatc cattattatc
    21061 gatgctttag gtctgttagc aggaggaaga ggttcaagcg attatatacg tcaaggagca
    21121 gaaaaatgtg tgcttgaagg gttgtttgaa ctaccaaaac aagaaggatt ctctgaactg
    21181 atggttgaat tagggatcga aacagatgag gacaatctga ttgttcgacg ggatatgtcc
    21241 ttaactggaa aaaatgtttg tcgagtgaat ggtcatatta tcacattagc taatctgaga
    21301 agaatcggca gttatttagt agatatccaa ggacaaaacg aacatcagga actgctccag
    21361 cctgaatcac atcttgcttt attggatcgt tttggagatg tagctttcca acagaagaaa
    21421 aagagttatc agcaagaata tatctcttat cgtgagctgg aaaaaagggt acgaaaagtg
    21481 cagcaaaatg aaaaatccta tgttcagaga atagatatgc tccatttcca gcaagaagaa
    21541 atagctgctg ctgatttgca agtcggagaa gaagagaaat taaaagaaga aagagaaaaa
    21601 cttagcaatt atcaaaaaat tgctgatgga ttagctgcag gttacggagc actgacgaat
    21661 aatgaacaaa acagtgtaga tggtgttggc ttggccgttt cagaactgca agggatcgcc
    21721 catctagatg tggagtatga agcaatttat gaaaatatcc aaagtgctta ctatttgctg
    21781 caagatgcaa tcggcgatat gagtcgtcag attgatttat tggagttaga tgagagtcgt
    21841 ttagaagaag ttacgcaacg tttagaatta atccgacagt tgaaacgtaa atacggcgaa
    21901 tccattgagt caatattggc ttactatgac gaaatcaccg aagagctagc ttcttctgat
    21961 ttttcagaag gtcaattgga caaaatgaaa gaggaactag agcaaaaaga gcttctactt
    22021 cagcaacaag ccgcagatct tcatgaagcg cgtaaaaaaa tcgcaaaaga attggaaaaa
    22081 tccattctgc atgaattgaa aagtctgtat atggaaaaca ctgagtttga ggtacgtttc
    22141 ttaaaagaag aaaatagaca attgaatcat gatggatttg accaaatcga attttacatt
    22201 acgaccaatc caggagagcc actgaagcct ttggtgaaag tcgcttctgg tggcgaactg
    22261 tctcggatgt tgcttgcttt gaaaactatt ttttcttctg agcaaggtgt gacaagtatt
    22321 atttttgatg aagtggatac aggtgtgagc ggaagagttg cacaggccat cgcagataaa
    22381 atttctcaaa tatcgaaata ctctcaagtt ttgtgcatca ctcatctgcc tcaagttgct
    22441 gcagtcgccg actatcaata ttatattgtg aaagcagtga ttgatggacg tacgcaaact
    22501 tctgtttcag agttgaaaac aaaagaaaga gaagaagaaa ttgcacgtat gctggctgga
    22561 agtgagatta caaaactcac actcgaacat gcaaaagaac tattgaaact cgcaaaaagg
    22621 acctgagcca cctcgcagtg gttcaggtcc ttttcagcag ctgatagcta tattttattt
    22681 ttacatgaca ctcattacag cagtcaatac aacagatcca atcgttaaaa tcagcattgt
    22741 ccaaatgaca aattttgtta ctttagcaaa agtacttgtt tgtttttttt cacgcattgt
    22801 tttcaacctc gtcattaatt agttgattca agtgtacaat cttttttcca tttccacaag
    22861 agggcttttt tataaaaact tccctttttt taaataatag gtagttacga tacaaataaa
    22921 taatgttaat agaactagcc atataaaggc atcatccctt tcagcaatag gtaacttaat
    22981 gttcattcca tagatactgc cgacgattgt cggtatagtt aaaataatcg ttaaagaagt
    23041 taaaattttc ataatattat tcagattatt cgatacgatt gctgaaaaag tctgattcat
    23101 ttgttctact agttttaatt gaatgcgaga agtagtcatt gcctgctctg tttccaccaa
    23161 tacatcacgt aaatgatttt tcaaagcatg attttcttgg aaaagtttat tttgcgctag
    23221 ttctttcaat gcatctaaat tagcagaagt cgcttctctg aaataaacga ggcttttttg
    23281 gatatccatg atttgataaa gttgtttgtt ttcagtggat acttgaagtt tggcttccaa
    23341 agtatcgcat tgagattgaa gcgtagctaa ataactgttg taagagagtg tgacctgcca
    23401 aatgaattga aagaagatat tgagattagg cgaaatatca ctttttggaa aggtctggct
    23461 aaagactttc tttaaaaaca gtggttcatg attcgtaatt gtgataagct tctttttggg
    23521 cgtcaaaata atagagagcg ggtatgtatc cacttgaaaa taaccgctag gacttgtttt
    23581 agcaaaagga tattgtaaca ataataacgc tggctttgtc aactttgatt gattgaattc
    23641 ttctgtacgg gaattttctg catcgtccaa tatggaagtg atgtaatctg acggaatttc
    23701 aaattgatgt gtcagctgat gaatctcttc ttgattagga cgttctacac aataccagat
    23761 cgtttggtca gtttcctttc cggtattacg cagtttctca ttatctaatg taaaatattt
    23821 gatcatgatt ttcctcctgt tgcctgtttc ttttattata acggataggg aattggaata
    23881 catggaatgt gtttgtaaga tatagaatat aactgcataa atttaaataa aatgaaacag
    23941 ttgtgtaaag tatatacagt atacttgaag caacgataaa aaaggagttt acgttcatgg
    24001 gcacattcac accacttatc ttgttttggt atatttaccc ggtaatcgtt ttgtttggtt
    24061 gccaatttct tgtaaaatta ttttcgttaa atcgtcgttt taaaataaaa gcccctgatt
    24121 tggcgattcc ttttttgtgg ggcggtatgc atgcattgtc tagaaataca gggacaattt
    24181 ctatcttacc gtttttcttt atttctgttt tgctaatggg aatttgtatt gctgttttcc
    24241 aagcatatta ttatgaagaa attatttatc cgcgttattt caagatgact tggcgtttgg
    24301 tttttctgtt gacaatcgtc ttgtacgctg tcttgatcat tgtgaacata ctttcttacc
    24361 tatgaaaaaa atagaaaagc tgtaaaaagt cttttaaaag gctttttgca gcttgatttt
    24421 taaaaaaatg tttatgaata aaaaaagttg ttcccggatt tcccagaaaa ggtggtagaa
    24481 agtgggggat tgtggtagac taattttagt tagtggagga atggggggct ttcaatgttg
    24541 atgggtgaat tccaacataa tattgatgca aaaggacgtt taatcgtgcc ctcaaaactt
    24601 cgtgaagaac ttggcgaaaa gtttgttctg acacgcggat tggatggctg tcttttcggc
    24661 tatccgatga gcgaatggga aaatctggaa gctaaactga acgaaatgcc gttggctaaa
    24721 aaagacgcac gtacttttgt gcgattcttc tattcggctg ccactgaatg cgaacttgat
    24781 aaacaaggac gaatcaatat acccagcacg ttaagaaatt atgcagcttt gacaaaaggt
    24841 tgcgtagtca tcggtgtatc taaccgaatt gaaatttggg atgagacacg atggcaagat
    24901 ttttctgcag cagcagaaga gaactttgac gaaattgctg aaagtatgat tgatttcgga
    24961 ctataagaat aggaagaggc tgactaatga ctgaaacatt tcaacactat acagtcatgt
    25021 tgaaagaaac ggtagatgga ttgaacatca aaccggatgg cgtttatgta gactgtacac
    25081 tcggcggtgc cggacatagt gaatatttat taagacaact aagttctaaa gggcatctgt
    25141 atgcgtttga ccaagatcaa aaagcaatcg atcacgccaa gctgcgttta gcttcttatg
    25201 tcgaacaagg tatggtcaca tttatcaaag cgaacttcag agaattagaa gaacgcttga
    25261 gtgagcatgt agataaggta gacggcattt tgtatgatct aggggtttcc tctcctcagc
    25321 tagatgaagc agaacgtgga tttagttatc atcaagatgc accgttggat atgcgcatgg
    25381 atcagtcagc tcctttatcc gcttatcacg taattaatga atattcctac catgaattag
    25441 taaagatttt cttccgctat ggcgaggaga aattttccaa acaaattgct cgtgaaatcg
    25501 aacgagtacg aaaaacaaaa ccaatccaaa caactggtga gcttgtcgaa atcattaaac
    25561 aagtcatccc agctcccgca agaagaaaag gcgggcatcc tgcaaaaaga atttttcaag
    25621 ctgtgcggat tgcagtaaat gacgaactcg gtgccgaaga ggcctcttta gaacaggcaa
    25681 tccggttatt gaaagtcaat ggaagaatca gcgtaatcac attccattca ttggaagaca
    25741 gaattgtcaa aagtatgttt aaagaatata gtacggtaca agatctacca ccgggacttc
    25801 ctgtcatacc tgacgaattc caaccagaac tgaaagtcat tactcgtaaa ccaatccttc
    25861 cttcagagga agagctaaca gaaaacaatc gatcacgcag tgcaaagtta cgtattgcag
    25921 aaaaaataag aatgaaagag gagtagaatg atggcagaat taaagaaaat gcaagattac
    25981 gaatatgatt tacctgaatt ggtggatcag ccggaacaac aaatgcctga ttcttcttcg
    26041 aatcaagaaa tcattcttcc acaatcaccg gcaaaacgat taaagcagat ttctgctttg
    26101 gaaaaaattg ctgtggcaag cgtggcgatt gctattgttg ctttatgtgt tttaacagtt
    26161 atgctgcgca caaatatcag cggagctgaa aaagaaatca cgtcaataca aacagaaatc
    26221 aatgataaaa agcaagaaaa aacgagttta gaacaagaaa aaaacgaact ttctcgtact
    26281 gaacggatta aacaaatcgc agaagaaaaa ggattgtcta ttaatgacga caatttaagg
    26341 aaagtgaagt aaatgagtct taaaaataaa atttggcggt ttatggaaaa gaaaaatcta
    26401 aatccgatga acaatcgcaa aaaagtaggt atcattttat ttgctacgag tattggattg
    26461 ttctttttat ttgccgtccg tttctcgtat atcgttattg gaggtcatgt tgctggtacc
    26521 tcattagctg aaaaaacaaa acagttgtac caaggaagtg aagtagtaaa agcaaaaaga
    26581 ggaacgattt atgatcgtaa cggtgtggcg ctcgcagaag atgcctcctc ttattcaatt
    26641 aaagcgatac tctcaaaaac atatacctct ggggataaaa aactgtatgt tgaagaaaag
    26701 aattttgata aaatagcaga aatcctgcat aagaatcttt ctatagacaa aaaagatgca
    26761 ctgaatattt tagaggacgg cgcaaaaaaa gagctgtatc aagttgaatt tggtagctat
    26821 gggaaaaata tctcccaaga aaccaagcaa aacatcgaag cggacatgaa aaaagaaggt
    26881 gtcgctggtc tttattttgt cgaccatcag gctcggatgt atccaaatgg cgtcttttct
    26941 tctcatttta ttggatacgc agttccagac aaagatgaga atggcttagt tggtaaacta
    27001 ggtttggagt ctgcttacaa tgatatcttg agcggtaaag atggtaagat tatttatcaa
    27061 aaagataatt ttcaaaatcc tctgccaggt acagtggcag aagaagaaaa agctgtcgac
    27121 ggacaagata tctacacgac tttagacagc agactacaaa gttatttaga aacactgatg
    27181 gatcaagtaa atgaagaata tcagccagaa gaattgacag cagtcctgat gaaagcaaaa
    27241 accggagaaa tcttggcaat gggacaacga cctactttca atcctgaaac aatggaagga
    27301 ttgactggaa aagatgctat ctggcgtaat ttcttggtac aagatagtta tgaaccagga
    27361 tcaaccatga aagttttcac tactgcagct gctatcgaag aaggagaatt caacgagaat
    27421 gaaaccttcc aatctggaaa aatccaagta gaagatgcta cgatcaatga ccatgacttt
    27481 ggtgaaaaag gtgtgctgac catgcgtcaa gctctttcat ggtcaagtaa cgtcgggatg
    27541 gtcatactgg aacagcgatt aggcggacga tggtataact atttacaaaa actgggattt
    27601 ggacaaagta ctcattctgg attagatgat gaagtaaacg gtgctttacc tacattaaat
    27661 attgtcgacc gagcaatgag tgcttatgga caagcggtag gtgtgacgaa tttccaaatg
    27721 atgaaagctt tcacttctat tgcgaataac ggtacaatga ttcaacctcg atatatcagc
    27781 aaagtggtgg atccccaaac tggagaagag cgaacaactc aaacagaagt tctagggcaa
    27841 cctttttcaa aagaaacaac agaaaaagtc cgtgaatata tgagagatgt tgtcgaaagc
    27901 gaaaactacg gtagtgctta tggtgtatat agtgtacctg gatacaatgt atcggcaaaa
    27961 accggaacag cccaaatcgc ttctgataca gggggatatc aaacaggaga tacagcctac
    28021 ctgtattcga ttgtggagat ggttccttct gaagatccag actatgtctt gtatctaaca
    28081 atgaaacacc ctaagacata tgatcgaatg gcattggcta aaatcgcaaa tccattgatg
    28141 aaacgggcaa tggattttaa agaaactgaa gaagattcag atacagaaac aaaaacagaa
    28201 aaagtatccg tagccgatta tcgtaatctt gaagcggacg ttgcagcagc tgatgctcaa
    28261 aaaagtggac tgcaacctgt agtgatcggt aatggtaaaa aagtacaaaa acaatctact
    28321 gccaacggtg atcagttgat ctctggagaa aaactgatcc tatatactgg tggtgataag
    28381 ctgatgcctg acgtaacagg atggtcaaaa gcagatatca tgaagctggg gaaaatcctc
    28441 ggtattgaag ttagttttga tggagatggt tattgtgtca aacaagaact tgctccatat
    28501 gaaaaaatca ctgaagacaa acttagtttt actttagaag aataagaaga gaaataggag
    28561 agaaaagagc atggaatgga cacaagcatt gattcccatt gtcagcagtt gtgcaatgac
    28621 aattgccgca atgccgctat ttattggtta ttttcaaatg aaaaagcaag gtcaggcgat
    28681 tcgtgaggag ggaccaaagt ggcacaatag caaagccgga actcctacaa tgggcggctt
    28741 agtgtttctg atcggctcta ttttgacagg aatttgggtt ggagcttggc aaaaacagct
    28801 aactcctact cttttcatct tgctttttgt attagcgtta tacggagtaa tcggctttct
    28861 tgatgatttt ataaaaatat tcaagaaaag aaacatggga ctgaactcga agcagaaatt
    28921 gattggacag attctagggg gaatcatctt ttatcttgtt taccgttctg aaggttatcc
    28981 aggtgtattg aatttcttcg gactagatct acctttagga atcatttatg gtattttcgc
    29041 tctcttctgg cttgttggat tttcaaatgc agtaaatctg acagatggca tcgatggatt
    29101 agttgctggc ttaggaagta tctcttttgc agcttacggt ctaattgctt ggcatcagca
    29161 tcagtatgat gtattaatca tttgcttaag tgttttagga ggtttactgg gtttcttcgt
    29221 ctacaacaga aaacctgcca agatttttat gggagatgtc ggttcattag cgttgggcgg
    29281 acttttagcg gcaatttcta taatgctaaa ccaagaatgg acattgcttt tgattggttt
    29341 gatctatgtt atggaaacag caagtgtgat gcttcaagtt acttccttta agcttacagg
    29401 aaaacgaatt tttaaaatgt ctccaattca tcatcacttt gaaatgtgcg gatggtcgga
    29461 gtggaagatt gatacagttt tttggttgat cagcattgtg acttcgttga tcacattatg
    29521 gatcgtttgg taggagatga cgggaaatga aaaaaatatc aacatatgaa aataagaaag
    29581 tgcttgtctt aggactcgca aaaagcggag taagtgcggc caaattatta catgaattgg
    29641 gcgcacttgt caccgttaat gatggaaaac cttttgacga aaatccggaa gcacaagagc
    29701 tgctttcttt agggataaaa gtaataacag gtagtcatcc aatcgaattg ttggatgaag
    29761 aattttcatt gatggtcaaa aatccaggga ttccctacag tcatccttta gtagcaaaag
    29821 cccaagaaat gggtattccg gtaattacgg aagttgagct agcttacgaa gtagcggaat
    29881 gcccaattat tgggattaca ggaacgaacg gaaaaacaac gacaacaacg atgacaggac
    29941 tactactgaa tgcaggagca gatcaaggaa ttgcacgttt agcgggtaat attgggtatc
    30001 cagcaagtgg tgtagcgcaa gaagcaaaat cagaagataa aattgtgatg gaattgtcta
    30061 gcttccaact catgggaatc acagatttcc gccctcatat agcggtgatt accaatatct
    30121 atgaagcaca tattgattat catggtacaa gaaaagaata tgtcaaagct aaatggaacc
    30181 ttcaaaaaaa catgacagaa aaagattatc tgatccttaa ctggaatcag tcagaactac
    30241 aagaattagc gcaaagaaca aaagcacgcg tactgccttt ctcgacaaaa gaagtgttgg
    30301 aagacggtgt gtatgctgac gattactcaa tatactataa aaaagaaaaa ataatggaaa
    30361 tatctgaact tggcgtacca ggtaagcata atgtagaaaa tgcactagct gctatttctg
    30421 tagcaaaatt gtatggtata tcaaatgaag ctatacgaga aacgttgcat tttttccatg
    30481 gcgtaccaca tcgtacgcaa tatgtaggag aaatccaagg cagaaaattt tataatgatt
    30541 caaaagcaac caatatttta gcgactaaaa tggctctaag tggatttgaa acgtctaagg
    30601 tcgttttatt ggctggcgga ttagacagag gaaatacatt tgatgaatta attccttcat
    30661 taaaaggaat caaagcaatg gtcgtatttg gccaaacaaa agaaaagttg atggatgctg
    30721 gaaaaaaagc aggcatcgag acaatagtaa cagccgattc tgtagaacaa gcagttcctt
    30781 tagcattaga aaacagtaca gatggtgatg tagttttatt atcaccagcg aatgccagct
    30841 gggatcaata cccaaatttt gaaactagag gaaacagatt catggaagct gtgaaccgat
    30901 taaaatagaa aaagtagaag cgagcgataa aaaatgaaaa ttttggttac aggcggagga
    30961 acagggggac atatttatcc agctcttgcc tttgtcaatt atgtaaagac tcaagaaccg
    31021 aatgctgaat tcatgtatgt gggagcaaaa cgaggtctag aaaacaaaat cgtccctgat
    31081 acaggaatgc ctttccatac cttggagatt caaggattta aacgaaaaat ttccatgcat
    31141 aacatcaaga cggtccgatt gtttcttaag agtatccgtc aagcaaaaaa aatcctcagt
    31201 gattttcaac cagatatcgt tatcggtact ggaggatatg tttccggagc ggtagtgtac
    31261 gctgcagcca aaatgggtat tccaacagtt atccatgaac aaaacagtgt accaggtgtt
    31321 accaataaat ttttaagccg atatgtggat cggatcgctc tttcatttaa agatgcggct
    31381 tccttttttc ctgaaaacaa agcagttctt gtaggtaatc ctcgagcaca agaagtagca
    31441 gatactaaaa aatcagatat tttgaaaaca tttgatttgg atccagaaaa gaaaacagtc
    31501 ttgatttttg gcggtagtca aggagcactt aaaatcaatc aagcagtatc agttttttta
    31561 agtgaatata ttccttcttc ttaccaagtt ttgtatgctt caggagatag atattatgaa
    31621 gagatcctaa ataaaataaa tcctgaaata caaaatatta gtgtccagcc ttatatcaaa
    31681 aatatggcag aggtcatggc ttccagtgat ctgctggtgg ggcgtgctgg tgcaacttcg
    31741 atcgcagaat tcacagctct ggggttaccg gcagtgttgg ttcccagccc atatgttacg
    31801 aatgatcatc agactaaaaa tgcaatgagt cttgttcacg caggagcagc aaaaatgatt
    31861 gcagataatg aactaacagg tgaatcacta agtcagacag tcaacgaaat catgggtgat
    31921 gaagaattgc aaaagcaaat gtgccgagct tctaaagaac aaggaatccc tgatgcttca
    31981 aaacgtcttt atgacttagt aaaacaaata atcaaaaaat aaaggcggtg gtcttagtga
    32041 gtaagaaaaa agaaccaaaa aaattgtctc atccgtcttc tgatgaaaac aatttgactc
    32101 cttggcaaaa ggctaaccga aaatatctgg cagaacaaga gatgaaaaac caagagccaa
    32161 aaaaagaaga cataacatta gatacacccc tttcagattc tgaagaagaa aaaacggttc
    32221 aagaggaaca gcaagaagaa agccagtccg agaaaaaaat cgaatttttt gaagagatca
    32281 agcaaaagaa aaacggtgga ccatataacg gttctttttt gaaccggctg cccaatttaa
    32341 aaagtcaacg gcacaaagta ctatttcgtc ggttagcttt gatcatcact gtattgggta
    32401 taccgctgat ttttttgatc tattatgttt ctccttatag caaattacaa gcagttgcag
    32461 tatcaggcaa taagacagtc aacagccaag aaatcatctc tgatacaaaa ttgtcattag
    32521 gagaaaatgt ttggggacag tattttcatc gatctactta tatcgatcgc cttaaaaaag
    32581 cacagccaag aatcgaaaca gcaaatatac atttcaaagg gatgaatgaa ttcgatttgg
    32641 atgtaacaga atataaagag attgctttga tcgcaaaaaa caatcaatac tacccagtga
    32701 ttgaaaatgg aacagtatta gatgaaaaag tagcaaatcc tacaaaaaat ctccctatct
    32761 tggaagagtt caaagactct gcaaaaatca aagaattaac aaagcaatac aatcagttat
    32821 catcagaatt acaaaaagca atttctgaaa tcaagtacac gccaagagca agcaataaaa
    32881 atctgatcca attgaatatg aatgacggca atcaagttat tgtaaatatc aataatcttg
    32941 cgaaccaaat gaaatattat tcgcaagtag ccaaagatat ggatgaaaaa ggtgtgatcg
    33001 acatggaagt tggtatcttc tcgcatcctt acggtagcac tcaagaaacg gaagaatcgg
    33061 gccaatcgga agaaacaact gaaagtgaag aaaatgcgga tcaaacaaac gaatcaagtg
    33121 aagaggcaga aacgcaaaaa gcacaaacac ctggatcgtc tagcacaaac ggatcatctg
    33181 attcaaatga ttcaagtgaa acaagtcaaa tagaagataa tccaagtaca actccgtcaa
    33241 gtttaaatga aaattgataa aacaacttta aaaagtaaga atgtactttc taaaaaccag
    33301 taatttatgg tagaattgga agcagtgaat atatctatta ataagtatat tttaaaacgg
    33361 acgctagttg ttcgcttgta tatggaatag taagtaggag ggaatcccat tcatggcaaa
    33421 aacaggaatg tatgtaggcc ttgatattgg aacgacatct gttaaagttg tcgtggctga
    33481 atatatcgac agccaaatga atattattgg agtaggaaac gcaaaatcag aagggattaa
    33541 ccgaggcatt atcgttgata tcgataaaac ggtccaagcg atacaacgag cagtacgaca
    33601 agcagaagaa aaagcaggta tccagatcaa aggcgtaagt gtcggtttgc cagcaaacat
    33661 gcttgaagta gaaaattgcc agggaatgat tgcagttaac ggagattcaa aggaaatcac
    33721 cgatgaagat gtcagaaatg tggcttcagc tgcccttgtt cgttcaatac ctcctgaacg
    33781 tcaaatcgtg tcaatattgc cacaagattt tactgtcgat gggttcgagg gaatcaaaga
    33841 tcctcgtgga atgatcggcg taagattaga aatgtacggt ctgttgttta caggacctaa
    33901 aacgatcatc cataacatac gtaaatgcgt ggaaaatgcc ggattaatcg tcaacgaaat
    33961 ggtgattact cctttagcgc tgactgaatc aattctttct gacggagaaa aagattttgg
    34021 tacgatcgtc attgatatgg gtggcggcca aacaacaacg gctgttatgc atgataagca
    34081 attgaagttt accaatcttg accaagaagg tggcgaattt gtcactaaag atatctctat
    34141 tgtattaaat acgtcattta acaatgcaga agcgttgaaa ataaactacg gggatgcata
    34201 cccagaacgg acatcaccag atgaagaatt tccagtagat gtgattggtc agtcagaacc
    34261 agtgaaagtc gatgaacgct acttgtcaga aattatttca gctcgaatgg aacagatttt
    34321 caacaaagca aaagatgcat tggaccaaat cgaagcatta gagttgccag gtggcgtcgt
    34381 attgacaggc ggagctgcta gtcttcctgg tgttgtggac ttggcacaag aaatcttcgg
    34441 cgtaaatgta aaattgtatg ttccaaatca catggggctg agaaacccgg tatttacaaa
    34501 tgtaataagt atcgtggatt attcagcaaa cttgagtgaa gtgtatcaat tggcaaaaat
    34561 tgctgttacg ggtgaaacct cagcagctcg tcaaatggta gttgaacaag aaacaacaaa
    34621 cacatatgag agctatgaag cacctgaaga aacaatctac gatgagccgg aaccaaaaga
    34681 gtccggagaa aatgtaaaaa ataaaatcaa gggtttcttt acaaatattt ttgattaatt
    34741 catcctggga ggaataagat atggaattct caattgataa taatatcaat gacggcgcag
    34801 taatcaaagt catcggagtc ggtggtggcg gtggaaatgc tgtaaaccga atgattgaag
    34861 aaaacgttaa aggtgttgaa ttcattacag ccaacacaga cgtgcaagca ttaaaaaatt
    34921 caaaagctga aacagttatc caattaggcc ccaaatatac tcgtggttta ggtgctggtt
    34981 ctcagccaga agttggacaa aaagcggcag aagaaagtga acaatcctta cgcgaagctt
    35041 tagacggtgc agatatgatt ttcatcactg caggaatggg tggaggaacc ggtacaggtg
    35101 ctgcaccaat cgttgcaggt atcgcgaaag aattgggcgc attgactgtt ggtgtcgtga
    35161 cacgtccatt cacttttgaa ggaccgaaac gtggccgttt tgctgcagaa ggtatcgctc
    35221 gtttgaaaga aaatgtggat acattattaa ttatctcaaa taaccgttta ttagaagttg
    35281 tagataaaaa gacaccgatg cttgaagctt tccgtgaagc agataatgtt ttacgacaag
    35341 gtgtacaagg tatctctgat ttgatcacag cgccaggtta cgttaacctt gactttgctg
    35401 acgtgaaaac agtgatggaa aaccaaggta cagcattgat ggggatcggt gtggctagtg
    35461 gagaagatcg cgtagtagaa gcaacgaaaa aagcaatctc ctctccattg cttgaaacat
    35521 ctattgatgg agctgaacaa gtacttctta acatcacagg cggtttggat atgacattgt
    35581 tcgaagcaca agatgcttca gatatcgtag caaatgcagc aactggcgat gtaaatatca
    35641 ttctaggtac atctatcaat gaagaaatgg gcgatgaaat ccgtgtgacg gtcatcgcaa
    35701 caggtatcga tgaatcaaaa aaggaacgca agtctagccg accagctaga caagcacaaa
    35761 tgcaatcacc tgctcaaaag actgtattag atatggatca agctaaacca acttcttcag
    35821 aagaagaaaa cagttttggc gattgggata tcagacgtga acaaaatgtt cgtcctagag
    35881 ttgatgattc caattttgac aatatcgaaa aaaaagaatt tgatacattc aaccgcgaag
    35941 aaacaaaatc tcatggcgat gatgaattaa atacgccacc gtttttccgt cgtaaaaaat
    36001 aaaggagagg aagagcacat gattgctgac aacttgcaga aaatcaagca agaaattcag
    36061 gattcgtgtg ctcttgttca tcgtgatccg aaagaagtta cattagtagc tgtaacaaaa
    36121 tctgttgaat ccgctcaagc tgaagaattg gttagagctg gcgttatgaa ttgtgcagaa
    36181 aaccgagtag ataaattatt agaaaagaaa caagatttat ttgattttcc tgaaataaag
    36241 tggcatttaa ttggtaattt acagcgcaga aaggtaaaat tgattgtaaa tgaaattgat
    36301 tactttcatg cgttggacag tttaagatta gcagaagaaa tccagaagcg gttagagaaa
    36361 gaattatcct gttttattga agtaaatgtt tctggtgagg aatcaaaaca tggaatttca
    36421 ccagatgagc ttttaccgtt tgtggaatct ttagctgcct gcacaaaaat caaggttgtt
    36481 gggttgatga ctatggcgcc taaagaagct tctgatgagc aaatccataa agtgtttggt
    36541 acgctgaaag aattgcgtga tcttgttcaa gcaaaaggtt atgcccatgc accatgtagt
    36601 gaattaagta tggggatgag tcaagacttt caaattgcga ttgaagaagg tgcaacattt
    36661 atccgtgtag gaacagcgct attcaaagac gaataaagga ggaacaaaaa tgccgctttt
    36721 aaacagagga gcaattgcta attttttcgg attagctgat gaggaagagt acgaatacca
    36781 agattatcct gaaacaacaa aaaaggctgt acagccaact aaaaaaaata caacacagaa
    36841 tcaatcaact cattctgtat ctgctgcgaa tactcatgaa aaacaaaaaa cggcgacttc
    36901 acgtcctgta acgcatgaaa gtattcagcc ggctgaaaag aaaaaagtaa ttgaactaca
    36961 tcaatcacct acaaaaactg tagcgaaaga aagaacagct tcaagaacct ctacacaacc
    37021 taaagcaaat cttgctggaa aaatcactgt aatggaacca agagcttatt ctgaagctat
    37081 ggcgattgct aaacgaatca ttgctggaga agcaacctta gtgaattttc atttagtaga
    37141 agaaaaacaa gcgagaagaa tcgttgattt tctaacagga acagtttatg cactagatgg
    37201 agatatcaaa cgtgttggag atgagatttt tctttgtaca ccgactggga tggagattga
    37261 cagttcaacc gctcaatctt ttgcagatgc gaatttgttt gatctgtaag aggaggaact
    37321 acgatttata ctattgcact attacttcat ttacttcaac gggcagccta tttctatagc
    37381 attatcttga tggtatatgc attgctctct tggtttccag gcgggtatca atcagggcta
    37441 ggacgattat tagctaagat ctgcgaaccg tatatcagtt tgttcgatcg tctgcctttg
    37501 aggattggac ccttggattt cacaatttta ggggcaatcc tgatcttgaa cttagccgta
    37561 caaggtttag cacagatcgt tatatggata actgtccatt tagtttattg attgaagcaa
    37621 caaaatcttt attctcagaa tagataggag gggaaaattt tggatgcaaa tgtataccag
    37681 cactttcggg cagatgaacg tacatttatc gattcggtag gcgattggat tgaacaggtt
    37741 caaggacaat atgcacccta tctgaccgaa tttcttgacc caagacaatc ctatatttta
    37801 gaaacactga ttcgacaaag cagtgatttg cgtttcatgt tttatggcgg atatgaacag
    37861 gcagaaagaa aaagatgttt gattttcccc gattattacg aacctgtaga ggaagatttt
    37921 gaaacagcat tgtatgaaat ccattatcct agcaaatttg ccagcctaag tcatgggaaa
    37981 atccttggaa ctttagtggg aacggggatc aaacgctctt actttggcga tatcatctcg
    38041 gacggtgatc gctggcaagt atttattgca aatgaggtgg atcattttgt tgctgcacaa
    38101 gtaacaaaga ttggaaaggt tgctgtacgc ttggaaccaa tcaaatacac agaaatgatt
    38161 atgccgaaag atagctggac acaagaaaga ggaacagtta gttccatgcg actagacagt
    38221 gtgatctctg agatttataa tatttccaga cagcggtcca agcagctgat cgaagctggt
    38281 aaagtaaaag tgaactggac agaaaataca agacctgatt ttgtacttga actattagat
    38341 attatttcag tcagaggtta tggcagagtc cagatccaag aacttgaggg gaagacgaaa
    38401 aaagaaaagt acagggtact gttcggtgta ttacgtaaat aaaataaaaa ggtggtttac
    38461 tcatggcttt aactccatta gatatccaaa ataagacatt cccgacaaaa atgcggggat
    38521 ataatcaaga cgaagtagat gatttcttag atttagttgt tcgtgactat gaggaattga
    38581 ctcaaagaaa tcgagaatta gaaaaagcag tcaaacattc tgaagaaaaa cttgagtact
    38641 tcaatgaatt aaaagatgct ttgaaccaat caatcatcgt agctcaagat acggctgata
    38701 aagtaaaaac aagtgcaagc aaggaatccg aagtgatcgt tacttctgca caaaacaaag
    38761 cagatgagtt agttgcgaac gctgaaaaac gtgcacatca attaacaact gatgcagaag
    38821 aaaaagcaag aaaaatcttg acagatgcaa cagaaaaagc aagacagctt gcgacagaaa
    38881 ctgaagatct taagaaaaaa acacgagtat tccatcaacg tatcagcttg atgcttgagt
    38941 ctcaattaga acaagtgaaa agtccggaat gggatgaaat tttacaacca ttctccagct
    39001 acgtgactga cagccatgaa gtgatcaaag aagttttagc aaaacagctt gacaatgaaa
    39061 atgatactga tgtaaactca gacacaggag tcatagaagc acctatgacg gcatttgata
    39121 cacaggctat tgatatctcg atcgtgcctg gtgaaaatga aaacgagtag aacagaaaag
    39181 cactttgtta ttcttaaagc gagccgatga gagtggaagt tcggtaagac actgcatggt
    39241 gaaagatcct ctacttgaga cctgcttttc cgaaattaga gtaagaagca gcggctgacc
    39301 tcgttattgg tcacagagag tttgcactag atagatgcaa ctaaatttgg gtggtaccac
    39361 ggcatgttcg tcccttgcgg ctgaacatgc ttttttgtgt ccggaaaaca aataaaggag
    39421 tgtatggttg aatgaaaatg aaagaaacct tgcaattagg aaaaacaaaa ttccctatgc
    39481 gtggtaattt gccaaaccga gaaggcgagt ggcaaaaaga atgggaagaa aatcgaatct
    39541 accaaaaaag acaagagttg aacgaaggaa aacctagctt tgttcttcat gatggacctc
    39601 catatgccaa tggtaatatc catttaggac attcattgaa taaaatcagt aaagacatta
    39661 tcattcgttc aaaatcaatg tctggctatc gtgcaccata tgttccagga tgggatacac
    39721 atggattgcc gattgaacaa gtattggcta ataaaggcgt gaaacgtaaa gaaatgtcca
    39781 tggcagaata cttggaaaaa tgtcgtgaat atgcactttc ccaagtagat aagcaacgag
    39841 cagatttcaa acgcctagga gttgcaggag attgggaaca tccttatgtt acattagatc
    39901 cttcttatga agctgcacaa gtacgcgtat ttggtaaaat ggctgaaaaa agctatattt
    39961 acaaaggatt gaaaccaatt tactggtctc cgtcaagtga gtcttcttta gcggaagctg
    40021 aaattgaata taaagatgta aaatctccat ctatttttgt agctttcaat gtcaaagacg
    40081 gcaaagatat tcttgatgaa gatacagctt ttgtcatttg gacgacaaca ccatggacat
    40141 tgccagcaaa ccaaggtatt gctgtaaatc caaaatttac gtatgtattg gtggaagccg
    40201 atggccgtaa gtttgtcgta gcgaaagatt tgctagaaac agtccaatca gaaatcggtt
    40261 gggaaaatgt aacagttcta aaagaatttg ctggacaaga aatggaatat atgactgcaa
    40321 gtcatccatt ctatgaacgt gaatcacttg tgattttagg cgatcatgtt actttagacg
    40381 ctggtactgg attagtccat actgctccag gacatgggga agatgactat atcgctggta
    40441 gcaaatataa actatctgta gtgtcacctg tagactcaaa aggattgttt acagaagaag
    40501 cacctggatt tgaaggtatc ttttatgaca aagcaaatcc tatgatcact gatctattaa
    40561 aagaaaaagg agctttgctg aagctagatt tctttactca tagttatcct cacgattggc
    40621 ggacgaaaaa gcctgtgatc tatcgggcaa ctccacaatg gtttgcatct atcgataaat
    40681 tccgtcagaa tattttggat gaagtagaaa aagtagagtg ggttatccca tggggtaaaa
    40741 cacgtttgta taatatgatc cgtgaccgcg gcgattgggt aatttcccgt cagcgtgcat
    40801 ggggagtacc acttccgatt ttctatgctg aaaatggaga agcaatcatc acaccagaaa
    40861 caatcgaaca tgtggcaaaa ttatttgctg aacatggatc aattatctgg tttgaaaaag
    40921 aagcgaaaga acttcttcct gaaggattta cccacccagg ttctcctaat ggcgaattta
    40981 caaaagaaaa agatatcatg gatgtctggt ttgattctgg ttcttctcat gaagctgttt
    41041 tacgtcagcg accagaatta tcattcccag cagatatgta tttagaagga tcagaccaat
    41101 atcgtggctg gttcaactca agtatcacga ctagtgtggc tatcaatggt gtagcaccat
    41161 acaaatcagt tatttctcaa ggatttgctt tagatggtga aggccgtaag atgagtaaat
    41221 ctttaggaaa catcattgca ccagaaaaag tgatcaaaca atttggtgca gatatccttc
    41281 gcttatgggt atctagtgta gattatgaag cagatgttcg tgtttctatg gatatcttaa
    41341 gtcaagtggc agaagtatat cgtaaaatca gaaatacgat gcgtttctta ttagcgaata
    41401 cagaagattt cgatcctaaa aaagatactg tttcgtacaa tgatttacgt tctgtagaca
    41461 aatatatgac cgttcgattg aaccaagtaa tcaaagaaat ccgagaagaa gggtacgaca
    41521 aatataactt catgcatatt taccgtacag ttatgaactt cttgacggtt gatctatcgt
    41581 cattctacct ggattttgct aaagatgtag tttatattga agcagaagat gattatcaac
    41641 gtcgttgcat gcaaactgtt ttctatcaaa cagctgtagc tttgacaaaa ttattgactc
    41701 ctatcattcc gcatacagca gaagaaatct ggtcattcct gaaagaagaa gaggagtacg
    41761 ttcagttaag cgagtttcct ggttatgaag agtttgcaaa ccaagaagaa ttgatggata
    41821 cctggactgc tttcatggac ttccgtgata atgtcttaaa agcattggaa gaagcaagaa
    41881 acagcaaatt gattggtaaa tctttggaag caaaactaac tgtttatcca aaacaacaag
    41941 ttcgtgaaat gttaaaagct ttggatgcag atattgcaca attattgatc gtttcaccag
    42001 actactttga agttatggca gcagatgaac aagtgccaga taacgctatg gtatttgatg
    42061 atgttgctat tacagtggaa aaagcagacg gggaaacttg cgatcgctgt cgccaagttc
    42121 gtaaagatgt aggagtagat gaaaaacttc ctcatctatg cggtcgttgt gcaaaaatcg
    42181 ttgaagactt ctatcctgaa gctgtagctg aaggattcga agaaaagtaa aagggaaaag
    42241 ggggtgtgac atgttctttg tcacaccccc ttttgttatc aatcgtttaa ttttccacgt
    42301 tcacgatacc agttatctgg ttgccagatc cattcgaatc cgtctttttc aagtagttcg
    42361 aaagctgctt taggtcccat tgatccagct ttgtagttgg gaaaatccgg ttgtgtttgg
    42421 tcccaagctt ttcgaatgac atccacgata tgccaagatt gagcgacttc ttcccaatga
    42481 gagaagttcg ttccatcacc attcaacgca tctaatagta atttttcgta agcttctggg
    42541 ctattttcaa ccatttctgc actatttcta aattccaatt tgattggttc cgtttcaaat
    42601 ccttgcccta cttctttccc attcaaggat aaagaaaatc cttcagttgg ctgaatatag
    42661 atcgttagaa cattaggtgg aagtgtcgta tcgtcacatg gttcatcgac agatgttttg
    42721 aatacattaa caggaacttg tttgaatacg atgttgatcc gagtcccttt ttcagtcaaa
    42781 cgtttgcctg tacgtacata gaaaggaaca cctgaccaac ggaagttatc gatagtgaat
    42841 ttgcctgcga cgaatgtttc agtctctgat tgagcatcca ctttgtcttc ttcgcgatag
    42901 cccttgaatt gtacaccatc caattcacct tgagcatatt gcccgcgaac gaagttttct
    42961 aacacttctt cttcgttata aatgcggata gctttcaatg ctttgatctt ttctgtacgg
    43021 atttcttttt cggaaaatgc tactggcggt tccattgcaa gtaatgctac aacctgtaaa
    43081 atatgatttt gcaccatgtc tttaagtgcg ccactatgat cgtagtagcc cccgcgatct
    43141 tctacaccga ggttttcgcc aaaagtaatt tggatattgt cgatatagcg attgttccat
    43201 tgagcctcaa aaatattatt ggcaaaacgg atagctgaga tgttttggat catttctttt
    43261 cctaaataat gatcaatcct gaaaatatct tgttctggga atacttctct gatttgctgg
    43321 ttcaattcaa aagcagactg gtaatcagaa ccgaacggtt tttctatgat caaacgattg
    43381 aagccatttt ttgtcataat attttgtgat ttcaaatgag aaacgatcgt tccaaaaaat
    43441 tgaggtgcca tagccaaata atagacacgg ttaccgttta attgatagtg tccatctaat
    43501 cggtcagaca attcttttaa tgtctgataa tgcgttgaat catttacatc atgggattga
    43561 tagtaaaaat ggcttgcaaa ggtagttgct tcttcatctg aaggattcaa tgcacggatt
    43621 gtttctttga caacttcacg gtagtgctca tcgctccagg gacggcgagc ggttccgatt
    43681 acagcaaaat gctcgcctaa atttcctttt ctgtaaaggc ggaacaaaga cgggtacaat
    43741 ttacgctggg ctaggtcacc tgtaccgccg aatatcgtaa acaatacatt tttttcatta
    43801 gacatgtgga tacactcctt tatattttat cgacaaaaat cgtgctggcc gccttaaagc
    43861 tgacggggat tttctttcta tcattttgga tagtgatcgg tccttcataa gctgcgatgt
    43921 caacgatctc atattcttcg ttgatattca ggtcaatagt gactaagtaa tccaacaatt
    43981 ctttttcatc aagcactcgt gcgatacgca cttttgtacc gacaggatag gactccaatg
    44041 tttgtcggcg ttcttcatgg acaacttcct cttttttagg aatcgatcct ccatgaggac
    44101 aatgttcagg atgattcaaa tagttttcta aatgatctgc aagatgttcc gaagtcacat
    44161 gttccaatac ttcagcatca tcatggactt cattccagct atagtctaaa tgttcaacta
    44221 aaaaaacttc ccataagcga tgtttgcgaa tcagactgct agctttttgc agtccgcttg
    44281 cagtcaattg tacaccttga taaggggaat gttctacaag ctcttctttc acaagtttag
    44341 aaatcatttc actgacagat gcagctgaga catctagact agatacgatt tgtttattgt
    44401 tgactttcgt tgtatctcca cctagttcta aaatgatttt caaataatct tctcgatttg
    44461 gtgtcatatt cgatcatcct ttcatggtaa aaaaccatca ttagtaagtg taacaaaaaa
    44521 aacgttaatt gactattttt ctaaataaaa aacaaaggat ttttagacgt ttttacaaca
    44581 aaaaacgaaa gatgatagag aagactcatt ctttcgttta taaaggatat atatatacat
    44641 tgggagggat ctatttttca gataacaact tatatgaagt gtctgcagat tcgtcataaa
    44701 gagtttgttc gggataagaa aagataagat aaaaaccata ctgatcacgt acgactaaac
    44761 gatattcatc tatttctacc acagatgtgc caagagactg accgttgatc aaaaacgtgt
    44821 aatcagatgt aatctgtaat tgttgttttt gctggctatc actaaagaac catgtacctt
    44881 gatactttga gagtccttct gacttttccg cttgtttttt ctttttcaag taaataaaac
    44941 ttgagagaac ggtaatgagt gaaccaagaa aatagatcat tttttttatc accaaatcac
    45001 ccctttatga gaaaataatc gcatagacat attctttctt ctttatttca ttgtaccgaa
    45061 taaaagctaa aatttctcta agactttcga ctggtttttt tactgttttt ctacaaatta
    45121 tgataggata catagtagga agaaaggtga cataatttga agtatcagca agtggaaata
    45181 gcttttttta ttgaccgccc gaatcggttt atagcacatt gtatgaaaaa agacggagaa
    45241 ataattattg cgcatgtcaa aaatacaggt agaggaaaag aggtcctgat accaggcgct
    45301 gaagtggcta ttgtatttgc tcctggacct aaacggaaaa ccgcctatga tctgattgct
    45361 gtaaaaaaga agggtgactg gtttaatatc gatagtcaat tgcctaatcg gctggcaatt
    45421 gatggtattt tagacggcac gatcctttta ccaggattaa ctggtccatt tacggtatac
    45481 aagcgtgaag taacttatct tcactccaaa tttgatattt atttagagac ggtggtcgga
    45541 caaaaagcat ttgttgaagt caaaggtatg acacttgaaa ataaagcgat tggtgctttt
    45601 cctgatgcgc ccacactcag aggattgaaa catataggag aattaacgta tgccgcacaa
    45661 gatggttatg ccgcttatgt cttgtttatt gctcaattcg aacatcttca tctggcaacg
    45721 atccatgaag aaatgcaacc agcactagct gatatggttc gacatgcgca gcaaagcgga
    45781 gttcaaatcc tcgcctataa ttgtcaagta tcggcagatg aggtaactgt caagcaggcc
    45841 attccatttg atgtagatat cccttttgaa gatcctatac aatagaaaga aggtaaaata
    45901 atgatcaact taggtattat cggaacaaat tggattactc atcaatttgt ccaagcagct
    45961 ttaagcacaa aaaaatatga attgacagcg gtatattcta gacatttgga aaaagcacag
    46021 gaatttggtt ctcattatga aggggatatc gaattcgcaa cagatttgaa gacttttttc
    46081 aatattactc atatggacac catttatatt gcttctccga atagtcttca ctttagtcaa
    46141 gctaagcaag caattttggc aggaaaaaat gtgatagttg aaaagccagc tttttcgacg
    46201 ccaaaagaaa tggatgaaat catccatttg gcaaatgaac acaatgtgta tttttttgaa
    46261 gcagcaagaa atatccatga atcaggtttt aaaaagattg ccgattactt accattaaaa
    46321 gacgagataa tcggtgcaaa tttcagctat atgaaatatt cttcgcgcta tgaccaggta
    46381 ttagatggag aagaaccgaa tatcttctcg actcatttct caggtggtgc attgatggat
    46441 ttaggtgttt accttgtata tgcagctgtt gcttggtttg gaatgccaaa agaagtccat
    46501 tatttcccaa gaaagatttc tactggtgta gatggtcttg gatgggggat cttacgttat
    46561 gagaattttt atgtatcgat ccagccaggt aaaatcggtg attcttattt accgtcagag
    46621 atttattttg actcaggaac gctagtgatg aatggagtca atgcaattga acaagcacaa
    46681 tttcatgatc gcgcgcataa agaaatcatt gatttggcgg taacagctgc agaaaatcca
    46741 atggcagatg aagcagagga ttttgccaat gtcatggctc atccgaaaga tccagcttgg
    46801 ggattgttgt atgaagagtg gatcgagcta gctagaaatg tgaaccaagt gatttatgat
    46861 ttaagaaaaa atggcggcat caaattcgat gcagataatg aggaagattt ttaatgaacg
    46921 aatttgtaca agtatttccc gaaaattggc agaaaaaata tgaggataaa gggtttatct
    46981 caccttctct tattcaacga gcagtttttc agccactaag taataaacaa agtatagtag
    47041 cggtttctcc tacaggttca ggtaaaacac tggcttatct ttggcctcta ctactaaacg
    47101 tggaaccagg tgaagcaagt gcgttggtca tttttgcttc ttctcaagaa ctagctattc
    47161 aagtagcaga tgttgcacgt gaatggggaa aagacaaaga gttgaaagtc caatctttgg
    47221 tgggcggagc caacgtcaaa cgtcagattg agggtttgaa gaaaaaacca gaaatcttga
    47281 ttggtacacc aggaagaata ttggaattga tgaaagcaaa aaaaataaaa gcacatcaag
    47341 tgaaaacaat ggtatttgat gaagcagacc agctatttga cgctgggaac agccaaatca
    47401 ttgatcaaat tcttcatcaa gctccaacag agtatcagct agcctttttt tcagcgacag
    47461 cagatcgttc ccttgaaagc attgaaaaaa tcactgggaa aacgtttgag acaattgacg
    47521 tgacagcaga ggacgattct cgaaaaggac tgagacatta ctttttacgt gtaccgatac
    47581 gaaagaaaga tgactatttg agacgtctca cgcatataga agattttcat ggtctgattt
    47641 tctttaatca actgactgaa ttaggcgtga tggaagaaaa attgctgtat agaggtgtac
    47701 cggtaggaag tctggcctct gatcagaaca agctactccg aaaagcagcg ctagaacaat
    47761 tcaaaaagaa aatggtcaga gcacttttga ccacagatgt ggcggctaga ggtttagata
    47821 ttacaggtct tccttatgta gtgaatgcag aagttccgtt aagtgaagaa gcttatttgc
    47881 atcgttcggg aagaactggt cgaatgggta atgaaggaat agtaattaca ctcgtacaag
    47941 ataataatct aagagattta aaacggcttt tacgtccatc aaatataaca cttgaagaga
    48001 tttttttata cggaggtaag ctgcaaactg agcagccaac caaagaagat gcagctcctg
    48061 cagtaaataa aaagtatgcg aaaacttttt ctggaaagga gcagaaccca gaatataaca
    48121 aagaaaaaat aagaaaaaaa gttaaaaata aatcaaaaaa agagagaaat aaaggagcaa
    48181 ggcgcaaata agcgcctttt tatgctatga ttatgaaaac gggaacaaaa ttggttgcca
    48241 gaggaggggt tatgtgaaag aacgtcaaga agagatcttg cagctattga cagaaaacca
    48301 acaaggattg acagcaagtg atgtagctga gcgcttaact atcgatcgaa gcaatgcaag
    48361 ccgatattta agtgaactat acaaggccca tcatattgta aaaaccgctg gccgaccagt
    48421 cgtttactct ttgccaacgg aaaagtcaaa atctgatgaa gtgcatgtcg actcttctac
    48481 gcaagtgact tttgaaacac tcgttggaga aaatgattct ttaaaagtca gcatacagca
    48541 ggcaaaagct gcgattcttt atccaccgcg ggggctgcat acgattattt ttggagaaac
    48601 tggtacaggg aagtcgatgt ttgctgaatg tatgtatcat tttgcaatcg attcagagat
    48661 gctttctgca gatgcgccat ttgtttcttt caattgtgcg gattatgctc aaaatccgca
    48721 actgctcttt ggacacatct ttgggatcaa aaaaggggct tacacaggag cagctcaaga
    48781 tagtcccggt ctaatagcca aagcagacgg cggtatattg tttttagatg agatccaccg
    48841 tttaccgccg gaagggcagg aaatgctgtt tactttcatt gataaaggta tttaccgtcc
    48901 gcttggagaa agtgcacaag tacatgaagc atctgttcag atcattgggg cgacgactga
    48961 atcttcagaa agtttcttat ctacgtttaa tcgacggatt cctatggcaa tcaccttgcc
    49021 gaatcttgct tcacgttcac tggatgagcg ttatgaaatc atctctcttt ttatcaaaca
    49081 agaagcgaat cgtttgaatc aacgtatcga tatcgaaaaa gaagcgattc ttgccttcat
    49141 gctttatgat gcggaaggaa atatcggtca agtgaaacga gacttgaaac tagtctgtgc
    49201 aaaatctttt ttacattacc gtactcatca tgagaaaaag ctaatcattc gaaaagaaga
    49261 actttccctt caagtacaaa aaggattact gaaaatcaag gaaataccgg aacgtctcga
    49321 ccgattcatg gacagcaaaa gtcagtattt gacatttgaa ccaggatttg ctgatgttgt
    49381 ctggtcacaa gatccagaac gaaacatgca ggtctataac gatattgagg aaaaagtcac
    49441 ttctctttcc gaaaccggtg tggagaacat tgatctagag accctcattt caaaagatgt
    49501 ggatgcttat ttccagacat atgtcaaaga attgactaaa agttcgattc ccaaagatct
    49561 tttgccagat gaaatctggc ggttaaccaa tcaattgtat gatgtggctg aaaaacggtt
    49621 agaccgtatt tataatgaaa aagctcgttt tgcttttgct ttgcatctgc aaagtacatt
    49681 ggatcgtgtg agagaaggtc atatgatcgt ccacccagat ttgaataacg tacggaaaaa
    49741 ttttaagaag gaatttcaag tagcaatcga tctttcaacg atcattgaag aagaagaaca
    49801 agttgagatt ccttttgatg aaatcggctt tattagtatg tttctttcta tcaatctagg
    49861 agaaagtgag cctgttaaag aaaacaaagt agatgttctc atattgatgc acggcagaca
    49921 gactgcttca agcatgttgg agatggcaca agaactatta ggaacaaaag tagggaaagc
    49981 ttttaatatg ccactggtta tggaagttca aacaatgtat gaagaagtgt tacaatatgt
    50041 caaaaactat caagagcatt tgacgaatgg cctactcttg ttaacagata tgggatcatt
    50101 aaacaccttc agtgatttga tttatgaaga gactggcatt cggacgaaag ctatcacgat
    50161 gacaagtacc atgattgtga tagaagcgat acggatggca agtgttggaa gaagcttaga
    50221 agatatttat caaaatatcc agctttcctt tgaatcgatc gtacgtgatc agttcaaagc
    50281 ggaaaagtct gaaactttac agcgtaaaaa agccgtaatc gtgacatgct ttactggtga
    50341 aggagtagct gccaaattat atcagcgtat tatgccagtg attaatcaaa ataaggtaga
    50401 actgatccag atgcagtttt tagaacgtga atcattcaaa aaacacatcg atgccttatt
    50461 ggaagaatat gagatcaaag caattgcggg aacagttgat gttgattatc aaaatatccc
    50521 atttttttca gcctatgacg tttttgatga tgaaaaacta aatattttaa agcgtatagc
    50581 tgatgatgag atcccgacag ctaaaattgt cgattcactt gctggatcat taagcgatgt
    50641 cttttctatt gatgaactga tccgttcatt gcaaaagaca gttcagcaga tccagaccga
    50701 tttgtcgatt atcgtggaac ctggagtaga tactggaatc gttatccatt tagccttcat
    50761 gttagacgga ttgatcaaac aagaaagcca tcggcaattt gagaaactgt ctattttctc
    50821 aaaaatttat cgtttggaaa tggatatcgt tcgggcaaac ttgatggcac tagaacgaaa
    50881 atatcaggta aaaattccag aagatgatat cgcatttctt acacaaatgt ttcttgaaaa
    50941 taaaataaaa aaatgaacac actaatcata ctgtttacac actaaacatc tgtgtgcgca
    51001 ctataaaaaa gagctaaaaa gcatgaaaac gctatttcag ctcttttttt tattggcatg
    51061 cttcttgcgt tatataaaag tgtaaaaaaa taaaaggagt gttaaaaatg gcaaaaaaaa
    51121 caatcatgtt agtttgttca gcagggatga gtacgagttt attggtcaca aaaatgcaaa
    51181 aagcagcaga agaaaaaggg atggaagccg atatttttgc ggtctctgcc tcagatgcag
    51241 ataataattt agaatctaag aatgtcgatg tattattatt aggtcctcaa gtacgtttca
    51301 tgaaagctca atttgaacaa aaacttgcgc ctaaaggtat tccattagat gtcatcaata
    51361 tgcaagacta tggcatgatg aacggagaaa aagttcttgc acaagcagaa aatctaatga
    51421 aataaatcaa gtatgcagtt gggggtataa caacgtggaa gatcaacaaa atctagaagc
    51481 catcatgggg ttaatcatgt ttggcggtaa tgcaaagagc gatgcaatgg aagcgattgc
    51541 ggctgctaaa atcggtgatt ttgagttagc ggataggaaa atcgctgatg cagaagaatc
    51601 acttatacaa gcgcatcatg cacaaacaga catgttgaca caagaagcac aaggaaatca
    51661 tatgcaagtg acattattga ctgttcacag tcaagatcac ttaatgacat ctattgcgtt
    51721 tactgattta gcaaaagaaa tcatcgaact ttatcgtcgc gtatacagcg aataaataca
    51781 acttcttttt tgaacggaag aagaaaaatt tttgaacgga ttttttattt tgttataagg
    51841 agaactctct ttatataaaa aacttatagg aggaagtaaa aaatgaacgg actatcaagt
    51901 tggatggaga aatacatcct gccggttgcc gcaaaaatcg gagcgcaaaa acatttagtt
    51961 gctttgcgtg atgcttttat cggcacactg cccgcaacaa tggcgggatc agtcgctgta
    52021 atgatcaatg caattattcg tgatttaccg caacagttta acagtaccta tgctgacagt
    52081 ttagcagcag acaaaggaat ctttgccgta ttgaatgtca tcatcggaat caatggtttt
    52141 gtctggaacg gtacactagc aatcgccgga ttgatctttg ccttttcttg ggggtataat
    52201 cttgcccgag cttatggagt aaatgatcta gctgggggga tcgttggttt agctaccttg
    52261 attcaaggta tttcctttgg tccagcatta tcagcagcat tagatgtgaa tgttccttca
    52321 aatgtcgcag atgcaatcaa tagttctgag attggtgcaa cgattgcaga tggcacactg
    52381 tcagttggat tatggggttg gctaaaacta gatcatttga atggaaacgc ttattttaca
    52441 gttatgatca tgggagctat ttcagtcatt attttttgta aattgatgct tgccaacatt
    52501 acgatcaaaa tgcctgattc agtaccacca gcagtatcta aagcatttgc agccatttta
    52561 ccagcgacga tcgctttata cgtcattgct attatcaatt atatcgtagg tcgtgtagct
    52621 gatgggcaac tgatcattga tttggtgcaa aaatatattg cagaaccatt cctaggatta
    52681 tctcaagggt tgggagcagt attgatcgtc acagtatttg ttcaagtatt ctggttcttt
    52741 ggtattcatg gaccaaatgt attggcacca gtgctagagg gaatctgggg acaagcacaa
    52801 ctaatcaata ttgatatttt ccaaaaaggt tataacggaa aaactggtac accagccgtg
    52861 ttagatgcaa tcgaagatgg aaaagcttat atgtgggtcc gcggatcgtt cgatgctttt
    52921 gcatggtttg gcggatcagg cggaacgatc gtcttactga tagctatctt gattttctct
    52981 aaacgtgcag attatctaac agtagctaaa ttatccattg ggcctggtat cttcaatatc
    53041 aacgaaccag tgatgtttgg tctgccaatc gtattgaatg caatcatgtt tatcccattc
    53101 ttgattgctc cagtagtagc aacagcaatt ggatggacag ctacttatct tggcctagtc
    53161 gctccggtat cgcagcaagt cacatgggta gtaccgccgt tcttattgtc attcttagca
    53221 acaggagcgg attggcgggc accgatcgta acattagtat gtatggtcgt gactttcttg
    53281 atttgggcac catttgtcat ctctgcaaac aaaatggacc ctgccgcagg cgaacaacaa
    53341 taagatgaac gtgaggagcg ggacgcttta agtttcgttc ctcataatga attttcgagg
    53401 aggaactgaa atgattacaa ttgccagtgc aatgcaacaa gatgaaatca aagaattgtt
    53461 agaaggatac aatgaagaag gaatgacttt tacatttaaa gaaaaacaag gaatcaagct
    53521 gttctttgaa acaagtgcag aagatccgga agttgcggct aaaaaagcaa aggaactaat
    53581 caaagcacag ccttggggaa cagtccttta ttttcaatca acagctgttt agaaaatggt
    53641 ttaaaaagat aggatggttg agatgataaa aaacggttta tttttatgta gtattggttc
    53701 tttgatcgtg ttgtatagtt tgaatccaca ttcgcaaagg tatgatttgt atagtatggt
    53761 cacaggtctt tttctaacag gattaggaat ctatttcttc atgaagggga aaaaaagaga
    53821 agaagcaaag gagaaaaata actaatggaa atcacgaaaa aattaaatat tccagcatcg
    53881 tttttttacg ataaagttat ggactctgtc cttttcgatg tacgtaaagc gaccggcaaa
    53941 tcagtaacta gaaaacagct gaaaaatttg gagtacgtca aacaattctc gcaaaataac
    54001 cgggctcgca taaaaatcga agaagtcatt gaaaaccagt cttataagtt tcgtacatcg
    54061 acaacgaaga atgaattcgt cgttcattat caaatcaaac cattggacga ttcgacctgt
    54121 gaggttcatt acacagaaaa aatggagtct tatggcatgc ttcaaaagtt gaatgatatg
    54181 cttttaggaa caatcttgat gtattttaaa cggagacgtt tcaaaaaaat gctagatatg
    54241 atcgaagcaa cgtattaaat caatgaaaca tggtactatt tagttattga aaaatgaagt
    54301 aagctagaag gaatttttca taggaagata gatctttcct gcgaatcctc actagctttt
    54361 ttgtaggaag gggcagcaaa atgacaaaca aagtaagaga gctaggtgta tcttcgattg
    54421 aggaaatgtt tgatttagcc acttatgcat ttaatggggc agatacacct gaaaggcgag
    54481 aacgttttcg tacacttgcg gagaattctt ggaattacgg attttttgat gaggaggatc
    54541 ggctaacaag tcaagtcatg gcgacccctt ttccagtgaa tttttacgga caagagtacc
    54601 taatggccgg cattggctat gttgcttctt atccagaagc aaggggacaa ggcgggatca
    54661 atcagatcat ggaaaagatc cttgaagatt gccgtgatcg taaagtaagc ttatcttatc
    54721 tggcgccatt ctcctatccc ttctatcggc gctatggcta tgaacaatca tttgataaaa
    54781 tcagttatca actaaacagt cgtgatgtgc cgtttatcaa aaaaaaatct ggaaaaataa
    54841 agcgtatgga ttttgaagat gcaaaagctg caatcagaag aatttatgaa cagatgccgg
    54901 aaaaccaacg agctggtctg aagcgcgaag actggtggta tacgtataaa ttcaagcaaa
    54961 aaggcaatta ccagtttgct ttgcattttg atgataatga ggaagcaacg ggatatatcg
    55021 tttatcagct tgcaacgtct tcctttatta ttgcggagtg gggatttttg gatcatgatg
    55081 ctttttgcag ccttgttcgc ttcgtaagtt ctcacaatgg tgcttttgaa acatttgaat
    55141 attcatgcgg ctacggcggt aatgatcaaa attatctatt agaaaatcca tttgcttctg
    55201 taatgatcac accttatatg atggcgagga tcgtagatat ttctttgttt ttggaaaatt
    55261 atccatttaa aaagagacaa gctgcatttg ccctacaaat agaagaagat cattatgcga
    55321 aatggaatga aggaatcgtg gaagtaacaa tcgaaaatgg aaaaaatcat ctctcaaaag
    55381 tagaacaaac aaaactccca atcgttcgag gaagtatcca acatatcacg cagctattat
    55441 tagggtatcg taaagtggaa gagttggtat tccaagaaag aatacaggtg acaaaagaat
    55501 atgaagaaac gttaagctca atcttgccac agcaacagcc aattcttaat gactattttt
    55561 gataaaaaac gggtgatgac aatatttttg tcaccaccct tttgtttttc atttggcatt
    55621 tgaaggaaaa tgttaaagta aatcctcttt tttcgtaaat ttgaattttt tgttttcttt
    55681 tgttttaggg ttttcttttt tgtggtcttg gattgcttct ttcgtaatct tttcccgatt
    55741 ttttttagat gaatctaagc gttctgcgta tactttttct tttggcttat cattcattgg
    55801 aaaggacctc cctacattat ttcattctac ctctagttta tcatctgtta aggactagtg
    55861 gaaacgtttt gcctaactta taagctgatt tttttagcag ataagcttgc aagtaaaaaa
    55921 caaacaagct acaattgatt tattgaaatt gttcctgtag ctcagtagga tagagcaatc
    55981 gcctcctaag cgataggtcg ctggttcaat tccagtcagg aacgtataaa taacccctgt
    56041 atcctttgcg gtacaggggt ttgttttgta tttgtgccaa aaatgtgcca aactagttat
    56101 catttttata taaactatcg aacacagtat tgattttttc tttatcctga tcttcaagct
    56161 ctcgaacaat atgaagataa gtagacattg tagtttctaa actgctatgt cctaaacgtt
    56221 tcgatacgct aagtatattt actccttgat aaagtaaaat agatgcatgt gtatgcctta
    56281 gtccatgcaa agtaaattgc ttttcaatcc ctaattcttt taattttttg cgcaaatatt
    56341 tgctgacggc gtttgatgaa actaatccat tttttaagtt gaaaaaaaca aaattatgag
    56401 ggtttttgat ttcaaaattc tcgaataatt ctttttgatt gattttaaac ttttttaaga
    56461 gatcaatcgt atgtttatca atggaaattt tcctatttga agtttcgttt tttgtttttc
    56521 cccattcatt taatttataa ttccatgttt tattaatagt gatgatttga tcttcgaaat
    56581 cgatatcttc ccatgttaat cctagaagtt cagcaaatcg cattccagtg gcaccagcaa
    56641 ctaacacgag cataggagaa gagtactgcg cagaaaggtt ttcttctacg agtttcatta
    56701 aagatttaaa ttgatcataa tctaaatatt tatcttcttt tggcttcaat gaatcttttc
    56761 ctttgattac tgcttttcta gttggatcaa acggaattaa tccttcttct acggcatctt
    56821 tcaacgacgc tctaatatgg ttattaaact taataacggt agattttaca tggtctttag
    56881 catacttatt taaaaagcgt tgatatccca ctctatctaa atcagaaatc aataccgctg
    56941 gcatatattt ctttatgttc attaacgtat cttcgtattt tctataagtg ataggagata
    57001 ctgttccttc tttataaagt tgcatccaat cctcaaagta atctgataat aatagatttt
    57061 tgcgatcccc tttaaggcct ttgttcaagt tatattctaa ttcgttggcg gcatcttttg
    57121 cttctccttt tgtcttaaat cctgattttc ttatcttcgt gtattttccg tcatcttttt
    57181 tgtatgaaat ttcgtattgc caactatttc cacgtttgac taatcttgcc ataattgaat
    57241 cagctctctt tctctgatac aataggaact ataaagaagc ccattgtttg ggttttatta
    57301 ttttttgcac atcctttttg cttgccggcg caaggatgtg ctatttgtcg ttttaatggt
    57361 ataattggat gtgtattaga tcatccaatc agaggtgttt attatgatta aagtgatttt
    57421 taaaagaata actgaacttc cagagtttag attatttgtt gattattggt atgtctggtt
    57481 ttttattgtt gcattgctga taggtctaga tgtcatatta gaaagaaaac ttaagtaaga
    57541 gttgagttaa taaattgaat tcctaaatga gatattttgt agcccatatt ttgtttgccg
    57601 acatcaccta atactatgga gctaatcgtt ttttctaaca gaccaaaatc agataatcta
    57661 tttaagctac catctattag ctcttgtgaa tagccagaca tgctgatatt tccagtgaaa
    57721 ttttcgtttc cacgactcat taagcatgct aacaattgaa tctcaatcga tgttaattga
    57781 ttcagtacaa gaagataata ctcctcgtta tcccatgaag cgttgttaat tcgaagtaaa
    57841 caattcttat aaagattttt atacatatct attttatttt gtgcctttga tttttctacc
    57901 tcgtcattta tcccttcgaa tattccaatg agttggtcct tgttctctaa gttgaaaaca
    57961 tcttctggaa tttgatcgcg aatgttttct aatgattcgt ttaaattttt gtagaatttc
    58021 tcgatgcgtt tgaaacgctt ctcgttttta gacccaaaat aaagtgactg cacaacgcca
    58081 ccaatataag gaattgctcc aataccgcct tcaactatta attcaagata ttcttttttg
    58141 gttagttttt cattgctatt atccatagtt acctcctatt ttgtcatttc ctttacaagc
    58201 attgtgactc ctgatggcac tcttttgtat aggttttatt attgtgcaca atctaactct
    58261 tagtggggcg tggttcattt attttttact tactttacta ttaatcatat cccattgagc
    58321 ataggatttt tctatgttcg atcctcttga actaatttct cctgtaaaag ttactttatc
    58381 gccctttgta aaggtatcag cattgtttaa gtccttcgca aaaattacat atgaaacttt
    58441 aggtgttgca gaaatatcat tccaactttt atcatcgtac tctttgtctg ctataatggc
    58501 tattctagta gtcattgatt cgataacagt tccttcaaaa gtatatgttt taccactaat
    58561 atatttagta aaagctgtat tttgctcagt agctggagta atagaataat aactatctaa
    58621 gaaagcaccc cagtcatgat tatttgtctc taaaaattct tcaaattgag ttaggctttt
    58681 attgctgctg ttagatgtag tagtttgagt atcagatgat gagctttcct gtttgttatt
    58741 gtcatttgcc tcgtttgatg aggaaagcga gaaacctacg gtagtaaaaa taatcccgat
    58801 aataaggaga atcataggtg ttttcttatt tgtttttttg ataaatctta caattaacat
    58861 gattaaacct ataataaata aaacaatacc agtaaaacca aatataccgt ccattaatag
    58921 atcctctttc tcttttgata ttgaatatta taaaccaagc aattcttttt tcttaaaatc
    58981 gaattcttct tgattaataa tcccttcatc taacaactct ttatactttt taatttcatc
    59041 tgcacttgaa atttgtgttt ctttggaatt attatctaat atagattgtt gcttctctat
    59101 atattttttt aaattttcca tttcattcca atattttttt gtaaacataa cggtgttttc
    59161 atctttcgtg gccgctaata tacctccgcg actttcgttt ccgcctagca aggtaaattg
    59221 tatataacca ttactcatac ctggtttttt taattgtacg gctgatatat ttttaaaggg
    59281 gatagttttt tctcctttaa taccttgatt aactaaattt ataaatcctt ttctaataat
    59341 tgaaatagaa tcatcagtta ctttaatcaa ggtttttcct ggagatttta ttaaaatctc
    59401 tttttccatt ttttcttcct catttctgtg atatgatttt ttttgtagaa gctcatatat
    59461 gaggaaagag cccgtgttgc agcacgggct tttttaatgt tttgctgaaa tcggtttttt
    59521 taataattct tgatgtattc atacatattg ccttgcgtaa gaatattttt tcttaaaata
    59581 gcattggcag acagcataac aagtgtatct gagcttattc tgaatagaat aatactccat
    59641 aaatttttcg agattaaact gagattcatc agtcagttcg ttctcaatat agatatttaa
    59701 taaaattaga atagctattt tatctgcttc tgtttcaaat tttgagtgaa aagttgtaga
    59761 agtatcgtac aaaactgaaa attcaaaatg agaggcgctg aaatgtgcaa gttcatgaga
    59821 taaatgaaag gcttctgcag tttcaccgta tagattttca ttcaaaaaaa tgattctggg
    59881 ttttggatag tagaaaccag gctctttcat ctccatataa actactttca aattgtattc
    59941 gctcaacatt tctttcaatt tcaaatacat acaaaccatc actccaacta ttcattttcc
    60001 tctaaagctt tagcaattgc aatcgcttta cgcattgtct ccttagatat ttcttttcca
    60061 tcaaaagaaa aaacagtatc gtcttctgat aaatccacat gtttaggggt ttctctttct
    60121 tctctaccta gaaggtagtc tacagagaca tcgaaatagt cagcaatccg acttaattca
    60181 tctgaattag gagtattatt tttccacttt gctagataac cgttagaata tccaaaatta
    60241 atttctaact gccgtataga tatctttttc ctcttcgcca agtcttttat tatttcatag
    60301 gtattcatcg ataaaacaac ctttctaaat gtttacaaaa aaagtttaga aaaatacgca
    60361 gaaataattt gactaattct gagtaatgag ctatactata tcttgtaaac agatttaaca
    60421 actaaaaaga caacaaaaaa cactattgat atgtaaatgc agaccgccaa gaaagcttta
    60481 aaatcaatgt ttttatgtct tatttaatta tgctcttagt atagagtatt actcagatac
    60541 tgtcaattga atttagaaaa aagttgttaa atttgtttac gaatataaaa gaaaggaatg
    60601 agaaatatga acacaccgca aatttttaat ttcgaacaaa acgaagttcg gacaatttta
    60661 gtaaatgatg aaccatattt tgtaggcaaa gacgttgcga gtgttttggg ttattcaaac
    60721 actaaagatg ctttgtcgcg gcatgtagat ttggaagata agatggggtc gcgaatcacg
    60781 acctcaggtc aatcaagaga gatgacaatc atcaacgaat ctggtttgta cagtttaatc
    60841 ttaaaatcaa aacttccctc tgccaaaaaa tttaaacgtt gggtaacaag tgaagtgttg
    60901 ccagcaatta gaaaacatgg aggttatcta actccagaaa aagtagaaga agctttgctt
    60961 aatccagata caatcattca attagcaact caactaaaag aagaaagaac tggaagatta
    61021 atcgcagaac aaaagattgc agagtacgaa cctaaaatct cctatttaga tagcatatta
    61081 tcttctacag attcagtaac aattagtcag attgcagcag attatgggat gtctccacaa
    61141 cagatgaata aattacttca taaactaggt attcagaaaa aagtcggtaa ccaatggtta
    61201 ttgtgcaaaa aacacatgaa ccaaggatac acaaaatctc atacaactga gatcccgaaa
    61261 gccgatggtg gcactaaaat tgtaatgaat accaaatgga cacagaaagg gcgtctattt
    61321 atctacgaat tactaaaaaa agaaggatat taccctcaaa tggatttaga ggaaattggt
    61381 tagaaaggag ttttagtatg actgacattg cagaaatcac tcaacgagat agagaaaaaa
    61441 tcaaagaata tgtcgaaagt tcaaagttct taacttacac catgcttgct gaaagatttg
    61501 gaattagcaa aagctactta tctttaattt taaacggtaa aaagacttct gcagaagcaa
    61561 acagaattat agattcgatt atcactatgt acgaattgta aagggaggaa cagctaatgc
    61621 aatatctaga agcaaaaatc ccaattccag aaggctatgt aattatctcc caagtggatt
    61681 atgaggagtt aaaaaaagct gatgatactg gtagatggat gacgttgcca gaagtgctag
    61741 aacggattaa cagaaaatat gattggttta cttctagagt tttaaagaac ccaagatata
    61801 gaaatattat cgatatcgag aaaaacaaaa atggatttgt ctattatcca gttgaaggaa
    61861 gagacacata tctattttta agaagtaaaa cacttgaatt tttagaaaca aatttttcgg
    61921 aaatcttaag gaggtaagcg gatgggtaaa tttaatagag cactagtatt cagcgcacca
    61981 ctaattatct acgctttagg tctttgggga agcagacaag cattaatcgg cacaattgta
    62041 tatatggtct ggatctttat ggggcttgat gaagctgaat atagagcgaa aaagccagtc
    62101 gggagggact gacttaacct aattaattaa aaattgtaac aaataacgca aaaataaagc
    62161 taatgaaatt gtattgttag gatctactcc aatagttata tttacaattt cggttactac
    62221 tagtcctatc aaagctgccc cagtttgctc taaataccac attttatctt tgtagaaagc
    62281 aggtgaagct tgttgttttt cagatggttc attagttata tctttgttct tggctgtatt
    62341 tatttcttca aaaagcttta tagaatcatc aaggactttc ctttgctcat taaggatatc
    62401 aaaaaactta gcctcaaact catcagatgg attagaagtg tctttaaaaa gtagattttt
    62461 tgtactaact tccggttcgg aagaaaatgc tttttctaat tcttgggtag ctacccctat
    62521 tctgaagtcg tacttagaca tgtcaacggc aaatttttct gtgattttag agatatcaga
    62581 aaaataaggt tttggcatag tagctgccat ttttttagca atattaaaac ttggagattc
    62641 taattgtttc tgtattgcga acaaagaagg aggaatcata ttagcaatag atttgttacg
    62701 tttctcgaca atttgaatga gagaatcatt gagtattgct tgcgaagcta taaaagtatc
    62761 ttgaattgca attaattttt tagcttgttc tatcgcaggc tgcatagcgt taacgacatc
    62821 tagagaagga gcaatggttt caccgattaa ttttgaagaa gctatcaatt tttgataata
    62881 aggagtatct gaaatatcca attatataca ccaccttttt acctaaatta taccaaaagg
    62941 gagagaaaaa aatgcaataa ttagtaattt tgaaaaataa agaagctgtg actacgagct
    63001 tacaagtcgc agaaacattc cgaaaggaac atagagcagt tttaaaggcg attgacgatc
    63061 taaaagatgg gcttgcacaa aagtatgcag acctattttg ggaagatgtg tacatccatc
    63121 cgcaaaacaa acaggcttat cgaattgtct atatgaatcg tgatggcttt actcttgctg
    63181 tattaggatt caacaatact caaaaagttt tagagttcaa attgaaatac attgaagcgt
    63241 tcaacgaaat ggaaaaggca attcgcaaaa atacagcttt tgacacaatt gaagacatga
    63301 tgatctatca attagaagaa atgaaagatg ttaaaaaaga tgtttccatg cttaaaaata
    63361 ctatgcgaat tagcggacaa caagagtttg aaattaagca aaaaggaaat acgaaagtta
    63421 tggaagttct agggggaaaa gaaagccgag cttatgaaga aatcagcaaa aaagtattct
    63481 caaaattttg gtctgaattt aaacgtacct tttcaatccc aagatatggc gagttacctc
    63541 gtaagagatt cgatgatgct gtttcattta ttgaaatgtg gttaccagaa actgcgattc
    63601 gcatggaaat cgatcaactg aacagacaac aaagactttt tggtgatgaa aatgaataga
    63661 gctgaagcgc taagaatcgg gacggtaatt gctaatcgct ggtggagaca caataaacca
    63721 atcatcctaa gccaacaaca tattgacaag caaaaagcat ggcaacaaat aaaaaagtga
    63781 ctccgccggc aagcaaagag tcacaaagaa aacacatcat aaggagattt tagcatatgg
    63841 aaaaagaact ttccactcta gatcaatatt tgactgatcc tagttggggc aaatcgaata
    63901 tcaaggaaac aaataatcga aaaatcagac gaaatctttt gacggatgaa gaactagcat
    63961 gtgatcaaga cgatttggga aattttgtga gtatttggga tcatgtctat cttatccatt
    64021 tatcgaggaa gtccaaaaaa cctgaatata tctatgtcat cgaagatggc ttgattgatg
    64081 cgctagaaga gtatgacaga gataacttga ttgatatctc ttattacgga tcaggtaaga
    64141 aatacattgc tgaaatggag gcagaatttg atgagtgaaa acaaagggac aacgactttt
    64201 gaaaaacttt ttagtcgcaa gttaaataaa atactcaaga aaaaaggaaa ttttgattat
    64261 ttatcttggg ctcacgcatg ggagattatg aaaaagaatg atccacaggc aacggtaact
    64321 attaatgagt ataaacacta cagagttgtt tctggaactc atcaagactt tcttgttgag
    64381 gaatataaac cttttcttat ggatgaaact gggacttatg tatctgtctc agtaacggtt
    64441 aaaggacaca cggaaaccga attatttcct gttttagatt atcgaaacca accagttgtt
    64501 aaaccaaatg caatgcaaat caataactca ttgaagcgat gctttgtgaa agcattggct
    64561 ctacacggac tgggattata tgtatttcaa ggggaagata ttccaacacc acctagaatc
    64621 gatacgaaga aattaaacat gctagagacg attctagaag ctttcaatga gcagatgggt
    64681 aaagatatga ccaaaacctt aatcgaatat gttaatgagc agacagataa attagggctc
    64741 ttagctgata acgttgaaac tattgaacag ttaagctatg agcaatgtgc cttgatggag
    64801 cgagcaatag cagctaagag aaaagaatta gataagaagt gatatgagtg tttaaaccat
    64861 taatcgattc atattcagcg gttctgaaaa agttcaaagg aaaagacata ggtgcaacca
    64921 tcaatgagga agtgaacatt gatcgactaa agacgatgta tgacggctac gatggtgatc
    64981 gagttattga aattcgtttt attgatccta gacgtttcac agtacagcaa cgaaacttca
    65041 tctatgcact cataggcgat attttcatcg atacaggcat gccaacggac ttctggaagg
    65101 aattctttta cttccgcttt gaaggtgtca cagggcgcaa aataagcctc aaagatgaat
    65161 cgaatacgac tgtgagtgat gctaacgtct tagcaaatat catcttagat ttcatctttg
    65221 aacatcatat tcctttcaaa gaaggctatg agattttacc agcgaatcaa gaatattact
    65281 tctacaaatg catcacaaaa agagtctgtt gcatctgtgg caaaacagga gctgatatcg
    65341 atcactttga caaagcgcta ggaagacgaa agcgcaaaga agttgatcat tcagagtaca
    65401 catttgcagc actctgcaga atccatcaca cggagaaaca caagataggt gtgatcaatt
    65461 tcaaaaataa atatcaaatc aaagggatca agttaaacca ggaaacaatt aagaaactta
    65521 gaataggagg ataaaaaata ttggctgaca ac
//
LOCUS       DACGLI010000007        61729 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.007, whole genome shotgun sequence.
ACCESSION   DACGLI010000007 DACGLI010000000
VERSION     DACGLI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.007"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(59..187)
                     /locus_tag="IXT22_000516"
     CDS             complement(59..187)
                     /locus_tag="IXT22_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4861910.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IXT22_000517"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IXT22_000517"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4861911.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="IXT22_000518"
     CDS             complement(1674..2729)
                     /locus_tag="IXT22_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4861912.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IXT22_000519"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IXT22_000519"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAQ4861913.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IXT22_000520"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IXT22_000520"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAQ4861914.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IXT22_000521"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IXT22_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAQ4861915.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IXT22_000522"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IXT22_000522"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAQ4861916.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IXT22_000523"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IXT22_000523"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAQ4861917.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="IXT22_000524"
     CDS             10491..12050
                     /locus_tag="IXT22_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAQ4861918.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="IXT22_000525"
     CDS             complement(12161..14092)
                     /locus_tag="IXT22_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4861919.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IXT22_000526"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IXT22_000526"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4861920.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="IXT22_000527"
     CDS             complement(15021..15773)
                     /locus_tag="IXT22_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4861921.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="IXT22_000528"
     CDS             complement(15932..16141)
                     /locus_tag="IXT22_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861922.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="IXT22_000529"
     CDS             complement(16152..17480)
                     /locus_tag="IXT22_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861923.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="IXT22_000530"
     CDS             complement(17845..18432)
                     /locus_tag="IXT22_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAQ4861924.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IXT22_000531"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="IXT22_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAQ4861925.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="IXT22_000532"
     CDS             complement(20012..21301)
                     /locus_tag="IXT22_000532"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAQ4861926.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="IXT22_000533"
     CDS             complement(21455..22387)
                     /locus_tag="IXT22_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861927.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="IXT22_000534"
     CDS             complement(22544..23203)
                     /locus_tag="IXT22_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4861928.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IXT22_000535"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="IXT22_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4861929.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="IXT22_000536"
     CDS             complement(24244..24534)
                     /locus_tag="IXT22_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861930.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="IXT22_000537"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="IXT22_000537"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAQ4861931.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="IXT22_000538"
     CDS             complement(26821..28176)
                     /locus_tag="IXT22_000538"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAQ4861932.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICARYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="IXT22_000539"
     CDS             complement(28200..29369)
                     /locus_tag="IXT22_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861933.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="IXT22_000540"
     CDS             complement(29366..30253)
                     /locus_tag="IXT22_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAQ4861934.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IXT22_000541"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="IXT22_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAQ4861935.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="IXT22_000542"
     CDS             34320..34841
                     /locus_tag="IXT22_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4861936.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="IXT22_000543"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="IXT22_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="IXT22_000544"
     CDS             complement(36284..36940)
                     /locus_tag="IXT22_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861937.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IXT22_000545"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="IXT22_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAQ4861938.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="IXT22_000546"
     CDS             complement(38477..39475)
                     /locus_tag="IXT22_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAQ4861939.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IXT22_000547"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="IXT22_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAQ4861940.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="IXT22_000548"
     CDS             complement(40491..41222)
                     /locus_tag="IXT22_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAQ4861941.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="IXT22_000549"
     CDS             complement(41226..42491)
                     /locus_tag="IXT22_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAQ4861942.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IXT22_000550"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="IXT22_000550"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAQ4861943.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IXT22_000551"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="IXT22_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAQ4861944.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="IXT22_000552"
     CDS             47833..49335
                     /locus_tag="IXT22_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4861945.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="IXT22_000553"
     CDS             49337..50074
                     /locus_tag="IXT22_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861946.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IXT22_000554"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="IXT22_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAQ4861947.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IXT22_000555"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="IXT22_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAQ4861948.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IXT22_000556"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="IXT22_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAQ4861949.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IXT22_000557"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="IXT22_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAQ4861950.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="IXT22_000558"
     CDS             complement(55574..56740)
                     /locus_tag="IXT22_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAQ4861951.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="IXT22_000559"
     CDS             complement(56756..56983)
                     /locus_tag="IXT22_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAQ4861952.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="IXT22_000560"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="IXT22_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="IXT22_000561"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="IXT22_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59630..60304)
                     /locus_tag="IXT22_000562"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="IXT22_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313658.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            60827..61417
                     /locus_tag="IXT22_000563"
     CDS             60827..61417
                     /locus_tag="IXT22_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAQ4861953.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17125 a        13258 c        10689 g        20657 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtatcta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt catagatgga atggcaacag tttttttgac
    61561 aaattttata aggtgcagaa cttctttccg tatgctattc cgattgtcct tgacaatgag
    61621 cctcctcgga tgtgacgatc ttcggcagga gctaacagtt aaagttagac tgcctcgcta
    61681 gcgttagcac atccgagctc attatcaagg attcgctgcg ccaatctct
//
LOCUS       DACGLI010000008        60950 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.008, whole genome shotgun sequence.
ACCESSION   DACGLI010000008 DACGLI010000000
VERSION     DACGLI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.008"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(146..1111)
                     /locus_tag="IXT22_000564"
     CDS             complement(146..1111)
                     /locus_tag="IXT22_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAQ4861954.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1345..2190
                     /locus_tag="IXT22_000565"
     CDS             1345..2190
                     /locus_tag="IXT22_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4861955.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2381..3568
                     /locus_tag="IXT22_000566"
     CDS             2381..3568
                     /locus_tag="IXT22_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4861956.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3574..3930
                     /locus_tag="IXT22_000567"
     CDS             3574..3930
                     /locus_tag="IXT22_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAQ4861957.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            3932..4270
                     /locus_tag="IXT22_000568"
     CDS             3932..4270
                     /locus_tag="IXT22_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAQ4861958.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            4665..5699
                     /locus_tag="IXT22_000569"
     CDS             4665..5699
                     /locus_tag="IXT22_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4861959.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5692..6378
                     /locus_tag="IXT22_000570"
     CDS             5692..6378
                     /locus_tag="IXT22_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4861960.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6402..7250
                     /locus_tag="IXT22_000571"
     CDS             6402..7250
                     /locus_tag="IXT22_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4861961.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7447..8220
                     /gene="sufC"
                     /locus_tag="IXT22_000572"
     CDS             7447..8220
                     /gene="sufC"
                     /locus_tag="IXT22_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAQ4861962.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8233..9519
                     /gene="sufD"
                     /locus_tag="IXT22_000573"
     CDS             8233..9519
                     /gene="sufD"
                     /locus_tag="IXT22_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAQ4861963.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9516..10751
                     /locus_tag="IXT22_000574"
     CDS             9516..10751
                     /locus_tag="IXT22_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4861964.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VIAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFKHGTI"
     gene            10738..11208
                     /locus_tag="IXT22_000575"
     CDS             10738..11208
                     /locus_tag="IXT22_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAQ4861965.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11213..12604
                     /gene="sufB"
                     /locus_tag="IXT22_000576"
     CDS             11213..12604
                     /gene="sufB"
                     /locus_tag="IXT22_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAQ4861966.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(12699..13841)
                     /locus_tag="IXT22_000577"
     CDS             complement(12699..13841)
                     /locus_tag="IXT22_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4861967.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(13880..14614)
                     /locus_tag="IXT22_000578"
     CDS             complement(13880..14614)
                     /locus_tag="IXT22_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861968.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            14849..15124
                     /locus_tag="IXT22_000579"
     CDS             14849..15124
                     /locus_tag="IXT22_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861969.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            15222..17219
                     /locus_tag="IXT22_000580"
     CDS             15222..17219
                     /locus_tag="IXT22_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861970.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(17295..17630)
                     /locus_tag="IXT22_000581"
     CDS             complement(17295..17630)
                     /locus_tag="IXT22_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861971.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            17757..17972
                     /locus_tag="IXT22_000582"
     CDS             17757..17972
                     /locus_tag="IXT22_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4861972.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            18009..18371
                     /locus_tag="IXT22_000583"
     CDS             18009..18371
                     /locus_tag="IXT22_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAQ4861973.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWVSMVVSLAFIPVVFGAVAVIMGYLYRETDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            18417..18743
                     /locus_tag="IXT22_000584"
     CDS             18417..18743
                     /locus_tag="IXT22_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861974.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            18944..19720
                     /locus_tag="IXT22_000585"
     CDS             18944..19720
                     /locus_tag="IXT22_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861975.1"
                     /translation="MMKKNYLKTGIFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKI
                     PVDYNFKITKDRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKE
                     TTGISNITFMPIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQT
                     VDKKIDTFIKTYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVS
                     EQVGKDIPLRLLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            21494..22261
                     /locus_tag="IXT22_000586"
     CDS             21494..22261
                     /locus_tag="IXT22_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HAQ4861976.1"
                     /translation="MVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGIKEACEE
                     LQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGVELLEDN
                     AQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKRTPDDNP
                     IIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLDLFSFDD
                     EVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            22239..26636
                     /locus_tag="IXT22_000587"
     CDS             22239..26636
                     /locus_tag="IXT22_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4861977.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(28076..28741)
                     /locus_tag="IXT22_000588"
     CDS             complement(28076..28741)
                     /locus_tag="IXT22_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4861978.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            28867..30903
                     /locus_tag="IXT22_000589"
     CDS             28867..30903
                     /locus_tag="IXT22_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAQ4861979.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            30907..31545
                     /locus_tag="IXT22_000590"
     CDS             30907..31545
                     /locus_tag="IXT22_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4861980.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            31573..32001
                     /locus_tag="IXT22_000591"
     CDS             31573..32001
                     /locus_tag="IXT22_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861981.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            32458..33369
                     /locus_tag="IXT22_000592"
     CDS             32458..33369
                     /locus_tag="IXT22_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4861982.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            33586..34023
                     /locus_tag="IXT22_000593"
     CDS             33586..34023
                     /locus_tag="IXT22_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861983.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            34118..35002
                     /locus_tag="IXT22_000594"
     CDS             34118..35002
                     /locus_tag="IXT22_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4861984.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            35226..38393
                     /locus_tag="IXT22_000595"
     CDS             35226..38393
                     /locus_tag="IXT22_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4861985.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSKYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            38413..38958
                     /locus_tag="IXT22_000596"
     CDS             38413..38958
                     /locus_tag="IXT22_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAQ4861986.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            38986..39441
                     /locus_tag="IXT22_000597"
     CDS             38986..39441
                     /locus_tag="IXT22_000597"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAQ4861987.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            39438..40196
                     /locus_tag="IXT22_000598"
     CDS             39438..40196
                     /locus_tag="IXT22_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4861988.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(40282..41022)
                     /locus_tag="IXT22_000599"
     CDS             complement(40282..41022)
                     /locus_tag="IXT22_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4861989.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            41083..42336
                     /locus_tag="IXT22_000600"
     CDS             41083..42336
                     /locus_tag="IXT22_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4861990.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            42658..42885
                     /locus_tag="IXT22_000601"
     CDS             42658..42885
                     /locus_tag="IXT22_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4861991.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            43008..43334
                     /locus_tag="IXT22_000602"
     CDS             43008..43334
                     /locus_tag="IXT22_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4861992.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            43402..44115
                     /locus_tag="IXT22_000603"
     CDS             43402..44115
                     /locus_tag="IXT22_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4861993.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            44425..45276
                     /locus_tag="IXT22_000604"
     CDS             44425..45276
                     /locus_tag="IXT22_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4861994.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            45397..47262
                     /locus_tag="IXT22_000605"
     CDS             45397..47262
                     /locus_tag="IXT22_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4861995.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            47276..48718
                     /locus_tag="IXT22_000606"
     CDS             47276..48718
                     /locus_tag="IXT22_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4861996.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCMDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            48826..49527
                     /locus_tag="IXT22_000607"
     CDS             48826..49527
                     /locus_tag="IXT22_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4861997.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQEILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            49699..50178
                     /locus_tag="IXT22_000608"
                     /pseudo
     CDS             49699..50178
                     /locus_tag="IXT22_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            50189..50695
                     /locus_tag="IXT22_000609"
     CDS             50189..50695
                     /locus_tag="IXT22_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HAQ4861998.1"
                     /translation="MDYKKRVQQMFLDSGVVLKETELERIEYTDFGLGAIETEGLNLF
                     VYENNERYCGKELVLLPYQTCPEHRHPPRDENEGKKETFRCRKGLVYLYVEGKETKKL
                     SCIIPKGQERYYTAKKEIILHAGDQYTIEQNIKHWFQAGATGAVITEFSSSSDDPSDS
                     FTNPAIYR"
     gene            51106..51681
                     /locus_tag="IXT22_000610"
     CDS             51106..51681
                     /locus_tag="IXT22_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAQ4861999.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            51681..52121
                     /locus_tag="IXT22_000611"
     CDS             51681..52121
                     /locus_tag="IXT22_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HAQ4862000.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVLAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFEKLPVETYVGEYL"
     gene            52137..52838
                     /locus_tag="IXT22_000612"
     CDS             52137..52838
                     /locus_tag="IXT22_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4862001.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDTFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(53336..53761)
                     /locus_tag="IXT22_000613"
     CDS             complement(53336..53761)
                     /locus_tag="IXT22_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862002.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGADSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATVTFTKIGNYRLKDKDGNIYSL"
     gene            53992..55317
                     /locus_tag="IXT22_000614"
     CDS             53992..55317
                     /locus_tag="IXT22_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4862003.1"
                     /translation="MKVVDRLSEKMLPIVSKMSSQRHLLAIRDSFIVTMPLVMAASVM
                     VLLNALIFSNATVQRILDLSPLAELASIVNNGTMSILAIIVCYNIGWNLATHYIQTGV
                     IDDPSFSPVHAGILSTAVMFILMSLSSTVTLMDGNTAEATGVFLQSLTSSSGLATAMI
                     AALVSTELFIKLAKMKSFKIRMPEGVPPAVAASFNSLVPEIVVILFFSVVVFTLNHTT
                     GLNVPQLIELAIQTPLKAFVLSVPGILFLQFFSDFLWVFGMHGSSILAPIRQAPLLQS
                     IQENMDAFSVGKEIPNIITEPFTNAFGLIGGGGCILPLVIAILWASKRQEQRSIAKFG
                     LTTCLFNITEPIMFGLPVVMNPIYMIPCAIIPSINLVIAYAATSLGIISKTVAAAPWI
                     TPPVIQSFIATGGDIRAAVLTVILIILDVFLFLPFVLAANKAKLAEGGY"
     gene            55319..57619
                     /locus_tag="IXT22_000615"
     CDS             55319..57619
                     /locus_tag="IXT22_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 3 glycosyl hydrolase"
                     /protein_id="HAQ4862004.1"
                     /translation="MYDYPYQNPKLTIRQRVEDLLSRMNIAEKVGQVNQHLYGWECYE
                     KNGDKIELTEKLKEHVKWGGGLGALYGLFRSDPWSKTDYKNGIPAKESWKVANLVQEY
                     VLQHSRWKIPVLLVEECPHGHQGLDGISYPTNIGRGNTFNVALLEQSSRLMAKELAAK
                     GVHLALVSTLDLAKDPRWGRTEECFGEDPILSARFSEAVVRGFQGEIISEKVSFLDQT
                     VEEINKKKDQIGVVLKHCIAQGEALGGHNSGTVTIGRREFSDIYGPLLKSTRNAVGVM
                     AAYNDIDGIPCHINRALFEQTLRKEIGYQGIVMADGVALDRLSDVFTDKKTAAAYALA
                     AGIDLSLWDETYTKIAEAIDNQVVDEKLLDQAVRRVLSVKFLLGLFEQPFANDPKEYW
                     DHLMEESEHLNLETAKESITLLKNDGILPLDQQVKNIAVIGPNAHDVYHLLGDYSAPQ
                     TEDRLKKKIVQEIKTEFPQSKVSYAQGCEVRNQEDQEEKLLEAVTLAQNSDVIIAVLG
                     GSSARNFDMEFLRNGAVSSKGINMDSGENVDVASLSLGGYQEQLIEQLYQLGKPIITI
                     LVQGRPYDLMKIESFTNAIATAWFPGQEGGKAIAQMISGRNNPSGRLSLSYPRNSRQL
                     PVYYYQRAASKQENYYDLSGSPFYPFGHGLSYTTFEYSQMEVKTDIDKVIISIKVKNT
                     GSVSGKTSTLVYVRLIDGVVIQRTKLLKAFRKDELRSQEERLLVFELTSEDFSYMDID
                     DKRHYAKKAVIMVEQQEKEIKCNWQE"
     gene            57626..58597
                     /locus_tag="IXT22_000616"
     CDS             57626..58597
                     /locus_tag="IXT22_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4862005.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMEKISEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISNRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHAIDGLIVFLSEEEWSGFEMLTKMSIPVVALNCPGGPAGIDTIVVNDR
                     ESVAKVIAHHGGQGHKTIGFIAAAQTDYVARERLAGAKEAVQKDPSIHLEIFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            58619..60016
                     /locus_tag="IXT22_000617"
     CDS             58619..60016
                     /locus_tag="IXT22_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4862006.1"
                     /translation="MKRYQFPKNFWWGSAASGPQTEGRISGDGKGENIFDYWYKNEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HHYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFQLFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKAYHEMDQSGVI
                     GIILNLTPSYPRDESNPEDVKAARIADAFFNRSFLDPAVKGEFPSELIERIKELDLMP
                     EIHPDDLTIIKENTVDLLGINYYQPRRIKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEKGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDRNGFEA"
     gene            60172..60795
                     /locus_tag="IXT22_000618"
     CDS             60172..60795
                     /locus_tag="IXT22_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862007.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWEEYKLTANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLVVLLLTHDGDKVARLKNGKVVTAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     ASSQKNESTELSPSDSGSGQTITGNEENQASIITNESSEGQYQTYGQ"
BASE COUNT        20459 a        10028 c        12764 g        17699 t
ORIGIN      
        1 ttacgacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccag
       61 tacaaaaaca tgaacagctg tttttgtttg gccgttctta ttacttgatg cagaacagct
      121 ttttcacaac ctattgaatc gattattaag cgattttttt agaaacaaat tttccatgtt
      181 tgctatgttc tttaattaag aaacgtacgt aatgagcaag aacgtagaag acaactacac
      241 ttgcaaacag acattccgca acttttaaga aatccaatac gctactatag atacctaaac
      301 tgttgaagta atgaacagta gtaaatatag ctgttgcaga gataacaagc gggaatgtaa
      361 aggctgcata gcttggataa aaacgaagct tgaacaaacg tggaagcata gacagcacaa
      421 cgaaatacaa tacttgagat aaagcgaaca atgctacgac aagataaaaa ttaggttcag
      481 caaagttttt aagataacct gttaggcaaa gagaaccagg tgctgcaacg atcgtaatca
      541 gcggacgtgt cggatgagcc atatttctta cgaaaaagac acgtttgatg atgatcggca
      601 ataagaacgc atagcagatc aatgaaatcc aaaagaaaat ttttccaata agcgggaaga
      661 agttcccggc agttacagtg atgaccccaa atccaacgta aatgataaac cagcttggat
      721 aaattgcttc aattgaaaga tcagctttga taacatggtg ataattgaaa taaaagacaa
      781 ggatcacttg gaagataaca gcgcacagcc aaatgaattt gacaattggt gcaatacttt
      841 catatgaaac aaaataagta caaataacca tgagtgacat cgtaaaagtt ggtgaaacgg
      901 aggcgatgat tggatcatgc aacgtttgtt tcgtgtgttc gaataagata aacaatttaa
      961 caaaaatgaa tatcataaga atcatagaga taccgccagt tagattgcct aaagcaacat
     1021 ggtgatagtc tttaaacaga tttccaaggg aagctaaccc aaggatcaac ccgcagatcg
     1081 ggatcggaat aattttcaaa aagttcttca tatataatat tctccttttt atttaataga
     1141 ttttagtacc aagatgaacg aatacattgt aaaatgaata ggaatgtatg attacgagca
     1201 agcagacagc tgattgtctt catctaagtt actagttgga tcagcaactg ttttgttgta
     1261 catttctatt atagatggtt ttttgtatat ttaaatcaaa tagtttttat agtaattatc
     1321 ataaaaagtt atggaagtgg tgccatgttt aagttattaa cgacttttcg agcagtatat
     1381 gaaacaagaa atttttccag agcagcagaa gtactgtttt tatctcaacc agcagtctcg
     1441 aatcaaatca aacagttgga gcgggaattg aatatcgatc tttttcaacg taacggaaga
     1501 aaagagatgc ttccaactaa gcaagccgac ttattatatg aacggacact ggttttgtta
     1561 gaagaatggg aagaaactca gcaaaaattg ctcaatgaac aaaatgaaga agaagtatgt
     1621 cggatcgttg cttcccacac ctttgctgtc tatcttttgc ctcagttgat gaaacatctg
     1681 atcaaaaggt ttcctaaagt gcattttgag atcgaaatcg cgaattctca tgaatcatta
     1741 gaacaagtag cgaaacatga atccgatttt ggttttatcg aaaagccatt agagacttcc
     1801 ggcgtacaaa gatactcttt gatggaagac cagctagtca tcgctgggga cccaaaaagc
     1861 aaattgtggc ttgtaagaga agcaaactct ggtgtttttc attatacgca gcgttatttt
     1921 gaagagatga atatccaaga taagaagatg atcgtgaaaa gtaacgatgt aattgttgcg
     1981 ttgctgaagg aaggaatcgg tcgctcgatt ttgtctaagc gctctgttcc agaaaatgtg
     2041 ccaatgactc cgttgaattt ccatcgatat ttttatttca tccaacgaac caatctggtt
     2101 tctgatcagc tgctagagat tgccgaagag atccttcgat acaatgaaag cacagaaact
     2161 tctcacagcg aggagaatct cagctggtag ataattgcat gtatcaaaaa aagttctatg
     2221 atacactaaa gataagcagt aggcttttgt actgcatttg ctcaagcaac tgcacaaacg
     2281 gaaagttaat ttttcccaaa tgtctatgga aagactttcc attatctaac tggaccgcta
     2341 taataatcag cagtatggtt tttaagaaaa gggatgaaac atggaaaaaa aattaaaagc
     2401 ttcgaacgat aatcgtattg attatggcgt gattttacca gtctttctgt tatgtttgat
     2461 tggtctgctc tcattatatg tagcacttag ccatgatccg aacaatccag cagtcttgaa
     2521 aggcgtaggg atgcaagttg tctggtattt agttggagcg gcagcaatcg ttgtcatcat
     2581 gcatttgaat tccaaatgga tctggaaact gactccttac ctttatggtt tggggttagt
     2641 ggtaatggga ctcttgctca aattctatga tcagaattta gctgcttcaa cagggtctaa
     2701 aaactggttt cgattcggtg cgtttacttt ccagccagca gagttgatga agattgcgta
     2761 catcttgatg atggcactga tcgtaactaa acataatacg caagtaaaag aacggacgat
     2821 gaaatcggac ttttggctga ttgggaagct cttgatcgtg acaataccgg ttttagcatt
     2881 gatcatggcc caagatgact ttggaacgat gcttgtcttt cttgcgatct ttggcgggat
     2941 tttcttgatg tctggaatct cttggcgcat catcgcacct gtagtaatct tggcagtagt
     3001 cgttggagca ggaacgatct tcttggttac gactgaaggc ggaagagact tgctttacaa
     3061 agttggcttc aaatcttatc agtttgcacg tattgattca tggctggacc ctttccatga
     3121 tacgtcagga atgagttatc agccggccca aggacttttg gcaattggta ccggtggctt
     3181 gtttggtaaa ggattcaacg taagcaatat ttatgtgcct gttcgtgagt ccgatatgat
     3241 ttttaccgtt atcggtgaaa acttcggctt tatcggtggt gcattcgtca ttttcttgta
     3301 ttttatttta atctatcgta tgattcgggt gtgtttcgat acgaataatg aattttacgc
     3361 ctatatcgca agcggtttga tcatgatgct gctgttccat gtctttgaga atattggagc
     3421 aaatatcgga ttacttcctt taacagggat cccattgcct ttcattagtc agggaggatc
     3481 ttcgatttta gggaacatga tcggtatcgg gttgatatta tcgatgagat accaaaatga
     3541 agcacctgca agatcttcaa ggaggtaaga aaattgtaca ccttttactg gtacccgaaa
     3601 tgttcaacat gcaaaaaagc caaagcgtgg ttagaccagc atggcgttag ttatcaaact
     3661 gttgatatga tcaaagaagt accgaaggcc tcaacgattg agacttggct agaaacgagt
     3721 caagtaccaa tccgtcgcct gttcaacaca agcgggatga aatatcggga acttggactg
     3781 aaagatcaag taggcgagtt tacggcttca aaagcgagcc aagtcttatc gacagatggt
     3841 atgctgatca agcggccact gatcttacga gaggaccagc ttgttgcaat tggattcaat
     3901 gaaaaaattt atgaaggaga actgatataa aatggcaggc aagcatttga agaaaaagga
     3961 caacctttgg atcttattta atggaaaaga atactgtgtt ggtttgacaa atgaagcgca
     4021 agaagaactt ggagacatca cgtttgccaa tctgccaaaa gcaggacaat cgctaaaaaa
     4081 agatgaacct ctgatcgaag ttgaagcgga aaaagcggtc aatgaatttg ccagcccgct
     4141 aacgggtaca gtttcttctg ttaatgataa aatcggtgaa gatatcaata tcttgaatga
     4201 ttcagatgaa atgaatgcgt ggatcttaag tttcaaagat gttgatccaa aagaatttga
     4261 cgaattataa aatcagaaaa tcacttgaaa aaagttgaca ctgattcttc cagttgctat
     4321 aatcataagc aatcctatat gaaacgagaa agctttgaaa agaagagtac atgtcacgga
     4381 cgtttgaaga gagccctgtt tgctgaaaat gggtaacgaa aatgagatgg aagatggtct
     4441 tagagcagag taagcgagcg taagcaaact tactacggga gtgcccgtta cagcgcgaca
     4501 gtatacggaa agaagctaag tccaagtact ggaagaggct gttattgcga agtaacggta
     4561 aatcaaggtg gtaacacgga agttcaagct ttcgtccttt tgcttaaggc aagagggcga
     4621 aggctttttt gtttgaaaaa tcataagaga aagatgtgaa tggcatgtca ttaatccaac
     4681 taacgaatgt caaaaagaca ttcaatggga aaaacggaaa catccaagcc gtcaatgacg
     4741 tttcactaaa cgttgaaaaa ggggatattt atggaatcgt cggctattct ggcgcaggaa
     4801 aaagtacatt agtccgtctc ctgaatggac ttgagcttcc cacgagcggc gaagtgatcg
     4861 taaacgatca agatattaca aaattaaaaa acaaagaatt acgtacattc cgaaagaaaa
     4921 tcggtatgat cttccagcat ttcaacctgt tatggtcaag aactgtactt gaaaatatcc
     4981 agctgccgct ggaattagct ggcgtaccaa agagcaaacg taaagaacgg gcagaagaac
     5041 tgttgcgttt agtcgggtta gaaggacgcg gacaagcata tccttcacaa ctttccggcg
     5101 gacagaaaca acgcgtcggt atcgcacgag cattggcaaa tgatcctgag atcctgcttt
     5161 gtgatgaggc tactagcgca ttggacccgc aaacaacaga agaagtatta gacttattgt
     5221 tagcgatcaa taagaaattg aatttgacca tcgtcttgat cacacatgaa atgaatgtga
     5281 tccgcaaaat ctgcaacaaa gtcgctgtga tggagttggg gaaagtcgta gaagaaggag
     5341 acgtattgac tgtcttcaga caaccgaaaa aagaagtaac caaacgcttt gtacaacaag
     5401 acatcgaacc agaagctgat tcgacagaac tattagctga actcatcaaa gaaaatccaa
     5461 gcggccgttt ggcaactttg acctttagcg aaagaaatgc caacgagcca gtcatttccc
     5521 aagcgattcg acgctataac atcgatgtca acgttgtgta tggaaagatc aaacaagtga
     5581 aagaaggttc ctttggttca ttgactgtct tgatgactgg tgaaaccaaa gaattagatc
     5641 aagcagaagt gttcatcaaa gaacaaggag taggaattga ggtgatccat cgtggataaa
     5701 agcttttcag aaacatatct agattttaaa caaatcaacc cggaaacgat gaatcaggct
     5761 atccttgata cactatatat gacattaatc tcaatggtct tagtgacgat catcggatta
     5821 gttttgggat tgatccttta ctctattgga cgcaaaaaca aaccgtatgc tcgaatcatt
     5881 tatggaatcg tatcgatcat cagtaatatt ttccggtcaa cgccatttat gatcctgatg
     5941 gttttgatca ttccatttac taaagcaatc gtaggcacta tgctaggtgc gcaagcagcc
     6001 attccagctc ttgttttatc cgcagcacca ttttatgccc gtctagtaga gattgctttt
     6061 cgtgaagtca gccctggtgt actggaagca gcagatgcaa tgggagcaag ttactgggaa
     6121 atcatctgga aggtcttgat acctgaaagt attcccgcat tgatttctgg attaacagtt
     6181 acaacgatct cgatgatcgg atttactgcg atggccggcg cgatcggcgc aggtggactt
     6241 ggaggtcttg cttggcagga aggctaccag cgtggtaatc tgacagtgac attcgttgcg
     6301 actttaatta ttttactaat cgtatttatc gttcaaggaa tcggtgattt cttaactaag
     6361 aaaacagaca aaagataata ggatataggg ggatgtagga tatgaaaaag aaaatttttg
     6421 gatttgcagc agcgcttttg ctgactgtag gattagcagc atgcggtaac aacagcgaca
     6481 gcaaagattc agcaaataaa gcagacgaca cgacattgaa agtcggcgct tcaccgacac
     6541 cgcacgcaga gattttggaa catgtgaaac cattattgaa agatgaagga atcgatcttg
     6601 aaatcgtcaa attcgatgac tatgtattac cgaaccaatc tttggaagaa ggcgacattg
     6661 atgccaatta cttccagcat attccttatt tgaacaaaga aatcaaagaa aaaggatatg
     6721 actttgtcaa tgccggtgct gtccacatcg aaccaatggg cttgtactct aaaaaagtca
     6781 aagatgtttc cgaattaaaa gatggtgcaa caatcattac ttcaaattct gaatcagact
     6841 ggggacgcat catcacaatt ctacaagatg ctggcttagt caaagtcaaa gatggagtag
     6901 atctggaaac agcaacattc gatgatattg aagaaaaccc taagaacttg aagttcaacc
     6961 atacgatcga cccatcactt ttagcttcta cgtaccaaaa tgatgaaggt gacctagttg
     7021 caatcaacgc aaacttcgct tacggcgcag ggttgaatcc attagaagat gccgtattgc
     7081 ttgaaaagga caactctcct tacgtgaata ttattgcgac tcgtaaaggt gatgaagaca
     7141 gtgacaaaat caaaaaactg attgaagtgc ttcaccgcaa agaagtccaa gaatggatca
     7201 cagacaaatg gggcggctct gttaaaccag taaaggctga tgcaaaataa ggtatggaac
     7261 aaaaaagatg agaaataagt ctgtaatggc ttatttctca tcttttttat acctattcta
     7321 atttagaaat caaaattgtt taataataaa taaaagatat ttgattttag taaggaaggt
     7381 cattgcgctt cattctcaat tagtctaaaa tgagtgagaa cgaaagagaa tttgggggta
     7441 taatgcatgt ctgtcttaga aataaaaaat ctacatgtgt cgatcgagga aaaagaaatc
     7501 cttaaaggcg taaacctaac aatgaaaacc ggagaaatcc atgccatcat gggacctaac
     7561 ggcacaggaa aatctacctt atctgccgct atcatgggca atccaaacta tgaagtaaca
     7621 gaaggcgaaa ttttgtttga cgggaaaaat gttttagact tggaagtaga tgaacgtgcg
     7681 cgacttggct tatttttagc tatgcaatat ccaagtgaga taccaggtat cacgaatgcg
     7741 gaattcatgc gtgcagcgat caatgcgaaa cgtgatgaaa acgacaaaat ttctgttatg
     7801 gcatttttga aaaagttaga tgaaaaaatg gctttactaa atatgccaga agaaatggct
     7861 gaacgttatc tgaacgaagg tttttctggc ggagaaaaga aacggaatga gatcctgcaa
     7921 ttgttgatgt tagaaccaac atttgcaatt ttagacgaaa tcgattcagg tctggatatc
     7981 gatgctttga aagtcgttgc taaaggagta aatgaaatgc gcggagacaa tttcggtgca
     8041 ttgatcatca cccactatca acgattattg aactatatca cacctgatgt cgttcacatc
     8101 atgatggaag gccgagtagt catgacaggg aatgctgacc tagctaaacg tctggaagca
     8161 gaaggctacg ctggtatcag taaagaatta ggaatcgact ataaagaaga agaagcgtaa
     8221 gggggagcaa gaatgaaaga aaaaaactgg ctcgattatc ttgacgcggt aaatgatttt
     8281 tctttaagta aaggcgaacc tgattggatg agaaccttcc gtcaagacgc actagcgaaa
     8341 gcagatgaac tgccattgcc gcatatcgat cgggtgaaat tccatcgctg gtcgttattt
     8401 gatgtgaaag aaacacaaac catcagtgaa acaggcacga ttccggcatt tgatgcaatg
     8461 aaagacaatc ctgtgcttgt ccaacaaggt tcatggacga tttttgaaca actgcctgtg
     8521 gaattagcag aaaaaggagt catttttacc gacttgttca ctgcaatgat cgaatatcca
     8581 gaactagtcc aagaatatta tatgaaaaaa gcagtaaaca tgaacgaaga ccaattgact
     8641 gcactccatg tagcttttat gaacagcggt attttcctgt atgtgcctaa aaatgtcgtg
     8701 atcgatgaac cactcgagtc cttattcatt caagatggcg catccgatga gcacttcttc
     8761 aagcatgtgt tgatcgtggc agatgaacat agtgaatttt cttatctgga acgtttccag
     8821 acaaccaaag aacaagtagc aaaatcatca ggtaatatca tcgtggaagt catcgctaaa
     8881 gctggttcaa aaatcaaata ttcagccgta gatcaattag gagaaaatat tacttcttat
     8941 atgaatcgcc gtgggcacat tttacgagat gcttctgtcg actgggcaat tggtgtcatg
     9001 aatgacggtc atgtgatcgc tgactttgac tcagatttag caggagaagg tgcacacgca
     9061 gaagtcaaaa tcgtggcaat cagctcgggc agacaaatcc aaggaatcga tacgcgagta
     9121 accaataaag cccctcatac gatcgggcat attttgcaac acggagtgat ccgagaaaaa
     9181 ggaacattga cctttaatgg tatcggccac atcttgaaag gggcaaaagg tgcagatgcc
     9241 caacaagaaa gtcgtgtctt gatgctttct gataaagcac gtggtgatgc gaatcctatt
     9301 cttttgatcg atgaaaacga agtaactgct ggacatgctg ccagtgtagg acgagttgat
     9361 ccagaagaaa tgtactatct gatgagtcga ggattgcata aagaagaagc agagcgctta
     9421 gtgattcgag gattcctcgg ttctgtctta acagcaatcc ctgtagaaca agttcggaaa
     9481 gaattagtcg aagtaatcga agggaagttg aatggatgat cgatgctaaa aagctacgca
     9541 atgattttcc tatcttattt caagacgtca atgatgaacc tttagtttat ctggataatg
     9601 cagcgacgac ccaaaagcca aaacaagtac tccaggcatt agcgcactat tacgaacacg
     9661 ataacgccaa tgttcatcgc ggtgtccata cgttagcaga acgcgcgacc catgattatg
     9721 aacaagcaag agaaaaagta cgggcgttca tccatgcaaa agaaacagca gaagtgctgt
     9781 ttactcgtgg tacgacgaca agcttgaatt gggtagccag aagcttcggc gaccgctata
     9841 tcaaagcagg agacgagata gtgctctctt acatggaaca tcattctaat gttatcccgt
     9901 ggcagcagtt ggcaaaacga acaggtgctg tcttgaaata tatcgaacta acagaagaag
     9961 gcttcctgga tatggaggat gcagcgaaaa agattacgga caaaaccaaa atcgtctcca
    10021 ttgctcatgt atccaatgtc ttaggtgtca tcaatcctgt tcaagaatta gctgaacttg
    10081 tccatgaaaa cggcggggtc atcgtagtag atggtgctca atctgccccg cacatgacca
    10141 ttgatgttca agcactagac tgtgatttct ttgctttcag cggacacaaa atgtgcggac
    10201 caacaggtat cggtgtttta tatggtaaac gaaaatggtt agaagaaatg gaacctgttg
    10261 aatttggtgg cgaaatgatc gattttgtcg aattatacga cagtacatgg aaagaactac
    10321 cttggaaatt cgaagcaggg acaccaaata tcgctggcgc tatcgcatta ggtcatgcaa
    10381 tcgattattt gcaagaactc ggcatggaca atatccatcg atatgaagaa gaactagccg
    10441 cttatgtgtt gccaaaatta caagcaatcg atggattgac tgtttatggt ccgcaagacc
    10501 cgaattttcg gacaggagtc attgcgttca atttggatgg gttacatccc catgatgtcg
    10561 cgacagcttt agacatggaa ggggtagccg ttagagcagg tcatcattgt gcgcaaccgc
    10621 tattgaagta ccttgaagta tcagcgactg ctcgcgccag cttttatttc tacaacacaa
    10681 cgcaagacgc cgaccgttta gttgaagcaa tcatggcaac aaaggagttt ttcaaacatg
    10741 ggactatcta aattagacaa tttataccgt caagtgatct tggatcattc ttcccatcca
    10801 catcatcgtg gaagcttgac tgactcgaca agcaagatcg aattgaacaa ccccacatgt
    10861 ggagatgtga tcgaattgca agttgatgta aaagatggaa tcatcaaaaa tatcgccttt
    10921 gacggcagcg gctgttccat cagtacagca agtgcctcga tgatgacaga tgccgtcatt
    10981 ggaaaatcaa tagaagaagc agaacattta actgtagact ttctacagct tgtccaagga
    11041 aaagaagtca aagatcccga ccaattaggc gatgctgcta tgcttggtgg tgtagctaaa
    11101 tttcccgctc ggatcaaatg tgcgacactt gcctggaaag cactaggaaa agcaatggaa
    11161 aacgatggta ccgcagcttt ccatcattac cacaaggaag aggagtgaga acatgggcgt
    11221 accagaatta gaagaatata aattcgggtt tcacgatgat gtcgaaccgg ttttcagtac
    11281 aggagaaggc ttgacagaag aagtgatccg tgagatgtca agaatcaaag gcgaaccaga
    11341 atggatgctt gaattccgtc tgaaatctct agaaacattc aataaaatgc caatgcaaac
    11401 atgggggccc gacctttcag acatcgattt cgatgccatc aaatattacc aaaaaccaag
    11461 tgacaaaccc gctcgtgact gggaagacgt accagaaaaa atcaaagata catttgaaaa
    11521 gattggtata ccagaagctg aacgagctta tctagccggt gcttccgcac aatatgaatc
    11581 agaagtcgtg taccataata tgaaagatga attcgaaaag ttaggaatcg tctttactga
    11641 cactgactct gctttgaaag aataccctga attattcaaa gagtactttt caaaacttgt
    11701 accgccaacc gacaacaaat tagcagcgct gaattcagcc gtatggtcag gtggcacctt
    11761 tatttacgtg ccaaaaggcg tcaaagtcga tgttccatta caaacgtact tccggatcaa
    11821 tgcggaaaac acggggcaat tcgaacgtac gctgatcatt gttgacgaag gagcaagcat
    11881 ccactatgtc gaaggttgta cggcacctac ttattcaagt aatagtctgc atgctgccat
    11941 cgtagaaatc tttacaagaa aagatgcgta ttgccgttac accacgatcc aaaactggtc
    12001 agacaatgtg tacaacttag taaccaaacg agcaaaagca tacgaaggcg caaccgttga
    12061 atggatcgac ggaaacttag gtgcaaaaac aacgatgaaa tacccaagtg tttacttaga
    12121 tggaaaaggt gcacgaggca ccatgctctc catcgccttt gcaggagcaa accaaatcca
    12181 agatacgggt gcaaaaatga tccataatgc accaaataca tctagctcta tcgtctctaa
    12241 atcaatttca aaagacggcg gagaagtaaa ctatcgagga caagtaacct ttgccaaaaa
    12301 cagtgcgggt tcgatctctc atatcgaatg tgacacgatc atcatggacg aatggtcgaa
    12361 atccgatacg atcccattca atgagatcca caacagccaa gtctctttag aacacgaagc
    12421 caaagtctca aaaatctcag aagaacaact ctactatctg atgagccgag gcctgaccga
    12481 atctgaagca actgaaatga tcgtcatggg ctttgttgaa ccattcacca aagaacttcc
    12541 aatggaatat gcagtcgaac tcaaccgatt gatcagttat gagatggaag gcagtgtagg
    12601 ataaacttgt tataggagct agaatccttg gtatataagg gttctagctt ttttattttg
    12661 tctatatact agaaatgacc agcttttgac cagctctttt actgatgagc catcatatca
    12721 gcaaagtctt gacctgtttt cttaggtgca ttatttgtaa tatgtgcata gatgtctaat
    12781 gtcactttac tattttcatg ccctaatcgt tgttgaacta ccttgacaga ttctcctgct
    12841 tctaataata aactagcatg tgtatgtcta aacccatgag gtgtaatacg aggcaagtta
    12901 tattttttca aaatatatct taaccaatca ttaacagtgt ttggaatgta tagagtgttt
    12961 ttaactgttg taaaaacatg ttgctcttta gagctagtat tgtatccaag ttttaaatac
    13021 tcttcttttt gctgtaattt ccagttgttg aggatagaaa gagtctcagt atctaaagag
    13081 ataactcgtc tagaagctct tgttttcgga gattgaatta taactttacc aaattcatct
    13141 acagcaagag ttttattgac atgtagttct ttattaaacg tgtctatgtc tttccactgt
    13201 aaagcgagta cttcactctt tctcatacct gtgtatgcca ataatctgaa gaaggcgtat
    13261 tgtttcatgt taccaaaatc tttaaaagca tccagtaaat tattaagctc ctcttttgag
    13321 taaaatttac gatttttctc atactctttt tttcgtggaa gaagtgtttt ttccatagga
    13381 ttattgtcaa tatattgcat tgcaaccccg tagcgtaaaa tttgtgcagt ctgttttctc
    13441 atataatcgt aactttcata tttactgtgc cattcatcta ccactttttg acaatatggg
    13501 acagagatat tcgatagttt aagcttacca aatgctggaa gtatttgatt atttgcgtat
    13561 cttactgaga ttgcgattgt tgaagcttta acactggtac gctgatgagt tatccattca
    13621 ttatacaggt cttcaaatgt catatcaggt gctttctttt taacaccgta taatatttga
    13681 tgtctgtact cgtcataatc tttttgagct tcttgtttgc tactaaaacc tcttctcgta
    13741 gtatttattt tttcaccagt tcgtggatcg gtggcaatgt gtcctttata catccacgcc
    13801 acttgaccgt ttttcttttt gtactttgat atttttgcca tgaaatcatc tcctcttagt
    13861 ttacaaggag tacttaccac tagatggtat cacctccctt catttttttc ttagtgtatt
    13921 ttttcccaat tgatgaaatc gtttgtttta gcttgtttat attatcaata atttcgttta
    13981 cagcttcttc gggataattc atgtcttcca cttgactatg tatcccttca tctatcattt
    14041 cttctagttg ttcctctata ctgctagtga gcagaagaat gttattgtca aattcttcta
    14101 taatagcatt gatgaataat tcttctattt ttaagatatt gaaaagacta attttttcat
    14161 ttttaacttt attacaagtc ttgttagcaa taaattcttg catctctggt tctaatttgg
    14221 aatatctatc cagccatgta tctaaattag agtgtactgg tgggaactgt tgacgaagat
    14281 gctggaacag gtttttatct ggaaatgtta taccatctag tacaatgcta tctctataaa
    14341 gaataattcc caaaatatat tcttctacat tgccacaaac taactcctct atactcatat
    14401 ttcccaaatc agcaattcgg gataatcgct ctggtattgg taaataggtt cccttttccc
    14461 attcgtagat agtttttttg tcaatcaatt gaccattgtt aatcataaga ccaaatgctg
    14521 gttgtgttaa ttttttactc tttcttatag cttttatttt tgttccgagt atcttttttc
    14581 gttctaaata atttattggt ggacgcttta tcatattgac cacacctcct aaaattagta
    14641 tacctcaaaa agggggtgtt gtaaataaat tcacacaaca tattgacacc ccttttgtat
    14701 cgaggtatta tgtgtatgtc gatgaactga taatcatttt ttatttgatt aatcggttaa
    14761 taacaacaaa atacttttat tttgatcaaa taatacgaag atgattctta gaaaatttgt
    14821 tcaagtaatc acgaaaggag ggggaaatat gtctctacaa atcattgata gcattgtttc
    14881 tatacaagtt gaacaacaag tgaaagagat aattacagtg ctaaagccta tgctagaaga
    14941 cattatttct ggtgttactc tagagtatat ggactatcag caggcaagtg aatatctagg
    15001 tgtatcagta ggaacgatta gaaaatatgt ttctcaatac gggttacctg ttataaaaat
    15061 tgatacggtc attagattca aaaaatctga tattgatagt ttcatggaac agtataaagg
    15121 ttgagtaaac aaataagact aaaacatata gtaataaaga gtttgtgttt attatctgta
    15181 tgttttagtc tttaacagaa ttttataagg aggaaacaca aatggaaaca tcaatgatta
    15241 atattccaat ttatgtagat caagaaaaat tattagagaa gccagttaca aaaaaagaaa
    15301 aaactgatgt aagagatagg tgtttagata actatagaga agttacaaga gatgagtttg
    15361 tagagatact aaattcatca caatcattta ttccaagcaa gacaaagaat aaaggcaatg
    15421 acaaggagag ttttgtggaa accagagtaa ttattctgga tgtcgataac actgttaaag
    15481 atgagaaggg gaaggtagta gatttgagta aagatgatag tagatactta agcgtagaaa
    15541 aggttttatc tatcaattta gttcataatt ctgcgtttgc gatacaaaaa agtattcggt
    15601 actctgaaaa tctagaaaaa tacaagattg tctttctatt aaaagaagca attactgact
    15661 atggtaaaat ggttgctgtt tacgaatact tgaaaaagaa catccccggg tgtgatgaca
    15721 atgtaaatgc ttcgaataga atgttttttg gaggatataa gtcagatgca gtgataataa
    15781 ttaatgaaga caacatgtta gatattactg agcttccgat tgattttacc atgacatgtt
    15841 ctaaaaattg tcaaagtgat tcagggagag agtatgaact agtcaatgaa accgattttg
    15901 ttaagttgat aaaaaatgac gacaaagaag aaatgaaaca gtggtttaaa gactgcctgt
    15961 ttgattcctc cgacatgtct tttaatgaga tttatgaaag attgttaacc attgatatga
    16021 ataaattact taagtcaagt aaaaacttaa gatgtctgtt tcacaacgat cataatccct
    16081 ctgctagtat ttttaccagt aaaactgggc attccatttt ttattgtcat tccagtaatt
    16141 gtgatatcag tgaaaatttt attggagttg tgatgctaat tttaaagaaa gacagtcggg
    16201 tagaaacatt taattggcta ttagagaacc tagacttgta tcctacacat tttcgaaaat
    16261 tgaaagagga atcaaaagta ctttttgaca ctcttgaatc aatgaaagac aaacttttca
    16321 ggacaataag gaattatcta gaggaaatgc gacgtgtcta tgatgtcttg ctttctgatg
    16381 ttaatttttt tgatgatagt aaggaaagtg tgacttgtat tttgtcgggg gaacaattag
    16441 ctaaaaaaat gagttcttac tatggtaaaa cttatgacat agataaatgt aataagttac
    16501 tatcacttat gacttttata ggattgataa aaaaattaga tgatgaagat gttcctttga
    16561 agatgctcga atacctaaat aggttaaagg aagagaaagc gttaggaaac tttaatcata
    16621 agagaagcaa tgtctatcga ttagacgttt ttaatgcaac ttctgtgatt caaaaattga
    16681 atgaagatat ccttccactt ctggaaaaaa ttcattttac atatcaatat ttttcttatg
    16741 aatgggttaa gatatgtttt aacgaaaaag aggctaaaag agtatttcct caaaattccc
    16801 gatcagaact cagcaaggaa aaacaattga ttttagatga agcacatgaa gttttacagg
    16861 gcttatcgtg gcaagggaca tatctaatga cagagaaaga acttattaac actgtttgtg
    16921 aacgcctacg taatgttggg gataacagcg tgaaaaatgc tttaataaaa aacagaggct
    16981 actttgttaa acaaggattc actcttgaac gagcttctaa ggatattaag aaactataca
    17041 atgtgaaagc aagtagtagt tttttaatat atttagcgaa aggggcaggg atagatgaaa
    17101 caataaaaga attgatatta tcaggagctg ggatagttcc tctgtatcaa tttacaagtg
    17161 taacaagaga tgatggacgg agagtaagga agagaaaaga cccaattgta ttaaactaga
    17221 caggttatcc atagctctta atcttatttc atctcaatac acccaccgtt aaagttcggt
    17281 gggttattta tttttcaatc tttcaatagc tgattgcgtt cattttcttg cctttttaat
    17341 agcttcatat agtcaattgt tcgaactgca tcttcagtgc taagagaacg atagagagcc
    17401 aaaaactctt cctcataatc tacgacaaca ttgtctagaa aatggcttac aggggttcct
    17461 agggctctag aaagagctgt taagctatcg aggttaggct ctgttacaga attttcccat
    17521 cttgctactg cctgttgtgt agagaagatt ttttcagcta attctttttg tgtccacccg
    17581 agagcttttc gcttttctct aatgaccttc gcatattgtt tctgtttcat taatacaccc
    17641 ccatctcagt atagtacaac aagttgttgt atttgtaatg gtatttgaag ttttttatat
    17701 tttatgagtt gaaatacatc atattgttgt atataataaa acaggagggg agaatcatga
    17761 aaaaagtaag taatctcagc cgatacagaa aagaaaaagg actttctcaa acggagttag
    17821 ccaaaaaaat gaatgttaca cagcaatgtg taagttcgtg gcaaacaggg agaacgattc
    17881 ctaaacccta tcaaatgaaa atgctttctg agatattaag tgtaccaata aacgagctgt
    17941 tttctgatgt gtttaataaa gtaaacagtt aactattaag caattgaatg attttaggag
    18001 gagaagacat gtattgtaga aaatgtggta aagaaataac agatgaaagt aagtattgcc
    18061 agttttgcgg agcattacaa gaaacagatg agacaactgg agcagacgaa gtaaagaaaa
    18121 gtactgagca gacatttagt gaaatgaagg aacaaatcgt acatggacaa gagacaggga
    18181 agctgtattt gattattggt tgggtttcta tggtagtatc gttagcattt attcctgttg
    18241 tatttggtgc tgttgctgtt attatgggct acttatatcg agaaacagat gagaaaatgg
    18301 gtacgatttt gatgatagca ggggtagctg gagcaatctt tggtgtactt ttagggatgt
    18361 caatgtactg ataagaggga taagagcaaa ttattttgga gataggagat aaaaagttga
    18421 ataaagtaaa tatgaacaag aagtttgtca ttataggtat cgttgtcttg gctattatag
    18481 gtatcatttt ttcaaaaatg acaggtacat ctggattaga gaagtcatct aaaccattgg
    18541 tgacacagat tttacaagaa cagtacaact taaataggtc atgtgatgat gtgacgatta
    18601 ctcatgaaaa tggagataac acataccggg ctaaagctac gttagacaat ggaagtgcta
    18661 tcaatataaa tgtcgagtac tatccaaaga aagaccgtgt atatgtagag ataccatata
    18721 ctgaggtgtt aatgttaaat tgatttaaat gtattatgta taccgtccaa acaggaactc
    18781 ctaaaggtgt aagcttacta aggagttttt ttgattccct gtaaataaaa tactaatata
    18841 gatgagaaaa ataatgttat aataattgat ggaaattgtt tttaaagagc tttaaaaatt
    18901 gggttcttac attgttgatt aaatgcttta aaagaggagc tttatgatga aaaagaatta
    18961 tttaaaaaca ggtatatttt tggttatagg aactatactg gttattcaat tatcaggttg
    19021 tagaaataaa gataaagatt tctatggata ttggtcagga actgctgaga aaattcctgt
    19081 agactataat tttaaaataa ctaaagacag agtaatagaa ctacaaaaaa atggtgaaat
    19141 ggtggatttt aagtatactc taagacataa aaaatttgat tcaactacat ttcgttcaat
    19201 catgatatca aaagatgaat tagttaaagc gattccagaa ttaaaggaaa ccacgggaat
    19261 aagcaatata acgttcatgc ctattgacgg tgaaaaagat aaattaactg tgttggtaaa
    19321 tttggatgaa cacttatcaa cagccactct ttataggact acgaaagatg agagtccaat
    19381 tggtaaggta gaaaagaaaa acgatacaat atcaagacaa actgtagata aaaaaattga
    19441 tacgttcata aaaacatacg cggctatacc acctacttgg aaacttgtaa atgaagataa
    19501 gggaataacg ataaatactg atacagagat tccgactgat gctcaatctt tatcagattt
    19561 attagctaat ctaacaggag tcagtaatgc ggtgtcagag caagtcggta aagatattcc
    19621 acttaggtta cttgaaaatg gaaaaaaaga ttattctgtg gtatttaaga acggaaaggt
    19681 aactgattac aacgaaatat ttgagaaagt cattgaataa tggtttttct atctttttat
    19741 taactaccct accccgttgt tttttgaccg tgtttcgaga ggaatcatta gaaagcatag
    19801 gctaactagg ggtttctttt tcttttattt tttgggaatc cgcttaagtg aaatgtatct
    19861 gaaatgaaac ggagataaag tgattttttg ctgtaatgac aaggttttag ctgtttcaga
    19921 taccatgtaa cccaaaatag tttattgaga aaataggaga gtatttgata ctaactagta
    19981 gggaaaaatg agataaaaag taaatggaat catttcaggt aatctgaaat aaaaaaatat
    20041 acagtcctgt ggcactttac ctatgggact gtatattttt tactctcagc gttttttgac
    20101 tccgtgtctg actccgtttt attgatttta tatgttattc agtgaccctt taacaggtca
    20161 atttttatgt ttttgtcttc gtatgactca gtttgatacc tagtgatttc catggtaata
    20221 cgggatgttg aacaagctag agaagttctg caggggttaa ttgcaaacaa ttcagataaa
    20281 caaattacaa tagattattt caagagggaa attaaaaaat cagaggaaaa atatttagat
    20341 ttaaagtcgg atatcctatt agcagacgat ataggttcac taactgtcga agaagatagc
    20401 ctattctacg tctattgtgc attgacttcg taaaagaaga cgtcttttcc aggtatacag
    20461 ttcttttatc tacttcatat gaaaatttgg gtacaaacga caaggaagtc agttttctgg
    20521 tcagactatc gtacgaacat cttgttgtgg tatttacact cagctttgat gatgagtaca
    20581 agagtttttc agcgaacaag acagaacatc gaaagaggtt tccagacgaa gttttacagg
    20641 ctgggctgaa gtattatcaa gaaggactca ccattaagaa gtctttatcg agaatataag
    20701 aagatacagg tatagaagtc agtcggtcaa cattctgtga ttacctaaac agcaaggagt
    20761 aacaggtgaa cgggaaaaag agcacaggga gggctatgtt cactggctga agaagcaaga
    20821 taaacctgtt tatgacttgt tctttgaaat aaagaaagct ttagatagtc agtcattaga
    20881 gaacttcatt gatgggtatg atgaaaagtt atctaatgag caaatgattg cgataatgaa
    20941 agaggtgttt cgtcagtatg ggttatcaaa taaacgtagg aaagaggttt ttgaccacgt
    21001 taagacaata atgagctttt accacacgac cctcggctaa atctaaagag ggcgaaaaag
    21061 ggacgagtgg taaaatttaa tgggaatagc taaaagtaaa taataataag tcaaagactg
    21121 cctagtttgg tggtcttttt tcatgttcat aaaaataaaa taggacagac gaacatcttc
    21181 gctaactccc ctgtgttgca agaggcaaac tctataattc tccagttaag ctatattttg
    21241 ttctttattt tgagatagag gaaaaaacaa aaatgtgtta aaattgaaca taagcataat
    21301 tagaaattgt cgagtttttt caagtaaaaa tcttgacttg taaggaggaa aagggcatga
    21361 tgacacgcaa tcacagtact agccagcagt ctgcccaaaa gcccatatat gaaagtgata
    21421 accgattcgt agcatccgtt tcggttattt gtgttgggaa gatgggtgat ttttagtggt
    21481 tgaagatatg gtgatggttg aagaggaaca aggacgacta atcaaaagta aaaaacgtgt
    21541 ccagaagcac ggtgaggtat ttacaccgca aagaactgtc aaagatatgt tggatttgcc
    21601 aggcataaaa gaggcttgcg aggagctgca gacgactttc ttagagcctt cagctggaga
    21661 aggtgctttc ttagttgagg ttttgactag aaaaatggca atggttgctc gtgaatataa
    21721 tgagtcccta gaacagtatg aaaattactc cttactggcg ctttcaactc tatatggcgt
    21781 ggagttactc gaagacaatg ctcagacctg tgtaatgaac atgtttcaag tattcaacga
    21841 tttgtacaga gaacaatcga aaaaacatgg taccgcaatg aaaaggaaag tccaagacag
    21901 tgcaaagact ttgatttcta ggaatatcaa acagggagat tttcttacaa aacgaacacc
    21961 agatgataat ccgattattt ttagtgagtg gacacctaag acgctaagaa aaggacagaa
    22021 aaaaatcact gtaaatcgaa ctgaatattc tttggaggat atttattcag gggtaacacg
    22081 agagtttgga gaggcatact cagctctgcc tgtatttgaa cagctcgatt tgttttcatt
    22141 tgatgacgag gtcgatgaag aagtttcaaa tgatccaata ttacgttatg tagcgatgcc
    22201 gataactgag gtttataagg aagagatgga ggaaattgat gacgacagcg ttgaaatcta
    22261 aagctaaata cttcgattac ttacctaaat atggttctaa gctagaacac ttccttggga
    22321 ttcctaattt agtagatgca attaacacgt accgtgtaac cgttaatcaa atacctaatg
    22381 aagttgctat tggaactaga cgttattcgg aggtagcagc acggaagatt gcttcaaatg
    22441 tgggtattga ccagcaaagt atgaagtatg ttgatgtact tcgcgagctt agggtcagaa
    22501 ataatattac tcctacgata gctgacttat ttcataagtt gagaaaatat ggaaatgttg
    22561 cagcacatga aaatggaatt atacctgttt cagaggcggt cgaatcttta gttactcttg
    22621 ataccttgct aagagtcttt gcacgcaatc tgtctgggga taaatcgtta aacccaaagg
    22681 aagaaattac ggatgagatg tttgttatca cctataacac ctttgaccgt aaacttattt
    22741 acatccagag tgccaaggat gctgacggca catggaaaat gtaccaagga ctggaaaaga
    22801 ttggggatgc atcagtacca gagaattatg aggcagactt tactcctaat agcgagtatt
    22861 taagagagta tgcaagtaga agaataaagc agtacatgac aacagcgggg gtaccttttg
    22921 tccttcattg ggcgcaattg gctgttaata agaagaacca atttttccgt gaccatgacg
    22981 tgcatgaagt attaaagcgt tcgggctata atcctcaaac gattggcgaa gatgacacag
    23041 ggaagcctaa tgagtggttc agtgtaacag ttgacgttgc caagaaagca atccaagcgg
    23101 ttaaagatgg taaaggtagt cttgactcag aaaaagatga ctttgacgag ttcaaaatta
    23161 attttagacc agaacaaaaa gatgctattg agcagactaa gactgtattc aaaacgaaag
    23221 atgagatgct ttggaatgcc aagatgcgtt ttggtaagac gctttcttct cttcaagtga
    23281 ttaaagagag ccaatacaaa aaagttctta tcatgactca tcgacctgtt gtaagtgatg
    23341 gttggtttac ggatttcaaa aaaatcttca cagatggttc gtacatctat ggttcaaaac
    23401 aagatggaga aaagattcaa aaccttgttg ataccgaaaa acctttcatc tattttgcaa
    23461 gtattcagga cttacgcggt tctgagtggg caggtggaaa agcaggggat aaaaactatg
    23521 aattcttagc gattgactgg gattttatta ttattgatga agctcacgaa ggaaacgaaa
    23581 cggaattagc taataacgta aaggctaagt tgcggaaaga gcataccaag gtcttagagc
    23641 tttcgggtac accatttaac cttttcgata agtatgatga ggataatatt ttcacttggg
    23701 attatactat ggagcaagaa gctaaggaga aatggtcagt agagcatccc aatgaaccta
    23761 acccatacga aggtttaccg aaagtatcta tgttcacctt tgaaatacca aataaatttg
    23821 attatttcga tgaaaataag gcatttaact tccgagaatt ctttagggtt aaggaagatg
    23881 atgaaacaaa gttgcttcat gaaggtgacg tacgcaagtt tcttgattat attactacaa
    23941 acgatgaaaa gactaatttt cctttctcaa aaccagagtt tagagaaaac ttacggcata
    24001 ctttatggct gatgccgggg gttaaagagg caaatgcttt tgaaagagtg ctcgaaacgc
    24061 accctatatt caaagattac aatattgcaa acgtagtcaa gacaggtgac agtgagcatg
    24121 ctagtgattc agatttagaa ttggtgcgta aagctattgg taatccagct aagtctaaga
    24181 cgataacctt aacagttcgc aagcttacaa caggagttaa tgttccagag tggacagggg
    24241 tatttttcct ttcaaacaca gaaagtccta catcttatct gcaggcagcg ttccgtgcac
    24301 agacaccttt taaccatgca gagcttggaa ttaagaaaaa ctgctacatc tttgattttg
    24361 cacctgaccg tgctttaaaa attatgagtg gaagtgtcgg actaactagc aagaagggaa
    24421 aggttaatag ttcagagcaa aagaaaaaac tagagcgcat gctaaatttc ttacctatcc
    24481 ttggtaaaca ggggaatgtg atgaaagaat ttagcgttga ccgaatgctt acggcactga
    24541 agaaggctta tgcagaaaaa gctgtacgga ctggctttga agacagctct ctttacaatg
    24601 acaacctatt aaatttagac caagctgatc ttaccaaatt tgaagacctt aaaaaaattg
    24661 ttggctcaag taaaccaacc aaagtgaaag acttcattgt ttcagataac ggtatgagtg
    24721 aagaggagta tgaaaaagct tcgagggcag aaaagaaacc aaaacgtcaa cgtaccaaag
    24781 aggaacagga agcaatagat agggcaaaga ggcttcgaga gcagcgaaat aaaatgattt
    24841 ccattttgag gggcgtttct attcgcatac ctatgatgat ttatgggatg gacattgata
    24901 ttaaagatga cgttactatt gagatgtttc ttaatttggt tgatgaggct tcatggaatg
    24961 agttcatgcc agaggggtta agtaaagggc gattcagaga gtttattgag tactatgatg
    25021 cagacgtttt tgtggaggca ggacgcataa tccgtagacg tgcaaagtct tatgatgagt
    25081 tagatgttat tgaacgtact aggaaaatag gtgaattatt tagcactttt aaaaatccag
    25141 acaaggaaac cgtattgact ccatggcgag ttgttaatat gcaccttggt aacactatcg
    25201 gtggactttc cttctttgat gaagaatacc aaaattctac ggagaacggt caaccaatcg
    25261 tgcgatggag gaaaactgac tgtacagatg atatttttaa ggaaaataga aagattcttg
    25321 agataaactc aaaaacaggg ctatatcctt tatatgcagc aacgagtatg tactatgttc
    25381 agctccttaa acaaagcgat attaatgctg gaagggtaga ttcagaggca atatgggaaa
    25441 aagtattatc agagcaaatt tttgtcattt ctaaaactcc aatggctaag acgataacga
    25501 agaggacttt gattggttat aacgcatgga aggtaaatgt tgaatactca agtgaattag
    25561 ttacgagtat gaaacgttca atcaatgacg gtttaacgaa tttgaaagga gtttataaaa
    25621 acgtgaaatt tgatgtgata attggtaacc caccttatca ggagaaagat ggaggttcag
    25681 gagctagtgc tacaccgcta tataatctat ttgtagaaac ctctgttaag ttatcagaac
    25741 gctatgtttc gatgattact ccttcgaagt ggtttgcagg tggtaaaggg ttagataagt
    25801 accgtgactt tatgcttaac agctctagct tgaaggtgat ggtggatata gtaaatggga
    25861 aagaaatatt cccaaacacc agtattggtg gcggtgttag ctatttcttg tgggataaga
    25921 aatataatgg attgacacag tatactaatc aacatgatgg tgtatcaaat acacaagagc
    25981 gaaaaatgaa cgagtttcca gtgtttgtgc gatataatga agccatttct gcaattcaca
    26041 aaattgggga acacgctagt gttggtgact ttgttatatc acgtaaccca tttgggcttc
    26101 caacgaaaat tcgaggggaa gaagtgcagg attccagaaa ttcaataaaa gtaatctcta
    26161 gtggtggggt aggctttgtt ccactggaag atatcactaa aggacaggat atggttggaa
    26221 agtataaagt cattagtagc tcactgacta gcgaacatgc aggtgaaccg aacaaaaatg
    26281 gtatgtttaa ggtgatttct actaacagag ttattaaacc taatgaagta gttacagatt
    26341 catacctagt gctattttct gctgataccg aaaccgaagc aattaattat ctgaagtatt
    26401 tacgaacacg tttttacaga tttttattac ttcaagcagt gacatctatt cacctatcca
    26461 aagataagtt catgttcata ccagtacaag attttacctc aggttcagac attaactgga
    26521 atgtaggtat tgaagaagtt gatatgcagt tgttcaagaa atattctttc gatgcaagtg
    26581 agatattgtt tattgaccaa acaatcgtcc cgattcttca cgaggaatat tactaagaga
    26641 acaagctaac aaatgaggct tagaaccctg ttttcttgat taattgcccc actttaaatc
    26701 aagatttaac tgtctattat caacaggtca aggtaaaata aaggatgtta gcaagtaaag
    26761 agattgattt gagtctacat cgaacaaggg aataatccaa taaaaaatga tttagaatat
    26821 caaaataaca aaaaagagga ctacctgtat tagtcctctt ttttgaccag attttgacca
    26881 gtctatttta cattctaata tattcatatg agctaatttt atgattaaat ggtaagtttt
    26941 tccttgtttg ttttagttta aactagtgtg taattcaaaa atctatatgg aagggtctgt
    27001 ggggtaatac ttaaataaag gctaggaacc tgataacatc aaggttccta gcctttttat
    27061 aataaaatga agcgaaaata atttctttta aagagccgag attatcagct atataagagt
    27121 gaatttgatg caaaaaacag agccgaaaca gtcttggtgt tcgtagctct gcttatatgt
    27181 ttcgaattta agacaaagag ttggcaaaag atgttgataa ggaagataag ataactgtgt
    27241 tatataaact aggtaactaa ctgtaacaag ctaattttaa gagattctta ttagaagacg
    27301 tttaggaata taactaagaa aatgattata caggtaattg tcatttcaat aatgttttct
    27361 aattttcgcg tctttgtttt aagaaaaagg ccagaatcag ttggaaaaaa gttcgtacga
    27421 tagtgaagag gggcaaaatt tcctactaat attcccacta acaagagata aaacggccag
    27481 gttggtgtga ttcctctata aaaaaatgcc catgctaccg aaatcccata gattaacaac
    27541 tgaacaattt ttacaatgaa aaaattgttc tgccattact caaagtctct tcctccttgt
    27601 atcgtttatt tgtttcattt tatcattatg ataggcgctt gaacaatcca ttttgtattt
    27661 tattgagtac tcttggataa actaccagcg attatcatat ttatttatgt tactgtaagc
    27721 catcatataa aagtaaatga gcagatcata gaaatataaa aaagaactaa aattgatcta
    27781 aattatgtgc agcttgacta cgtaccaatc tatattactt actagattgg tcgttaatct
    27841 attcggatcg aatgagcaaa atatttttgt gaatgtccat ccttgattat gattccaaaa
    27901 agaatcattg ggaggctgtg gcgtaaatat tatactataa gccagaaata cctatcattc
    27961 tgaacttttt tatttaggaa ctttcatctc aaggcttttt caattaattt gtacccctgt
    28021 tttttggata agatcatgtg cattgatttt ttctatctct acgttcatct cctacttaat
    28081 gcctatctgg ctcctgaggg cttcttttta aggcgtcgtc atagtcttgg ctgaggattt
    28141 cttggtaatc tgagggaatg gcttcccaag tgagcaggcg aacgttcatg acgtgttttc
    28201 ctttgtgttt gattacagca tggtttttct ctttttctac ctctccagcg tgaaaagaca
    28261 gccatgtacc atggccaaag atatcattac atacccaacg ttcgatggaa ttgtccacgt
    28321 atcctacagg gagtgtggta tagccgattt gtggtttcaa aaaaggattg aatcgatcga
    28381 tcgtttcatt tttgtattga taattgataa gaaaaagata gaccaaacaa aagacgagca
    28441 gaaagaaaga tagtgtcttt ttgagtgaga agggttgttt tgatgaataa gatttcttgt
    28501 taacaagagg ttcatctggc aatgttggtt ctattgattc ggtagctgat tcaatagaag
    28561 gaaaatcaat cggcagacct aaagtatgat gtaaaagtga cagcatttca aagtctggca
    28621 ttgtacgaga attttcccaa ctagaaatcg ttttatcgga aacaccaatt ttttcgccta
    28681 attctttttg cgtaagctta caatttctgc ggtaagttcg tattttttct ccggtgttca
    28741 tcttcttctc ctttcgattc tacagtatat agatttattc tacatgacct atacacttga
    28801 tagatacgtt tttttgatga aaaacggtat gattttatca aagaatcatt taagtaaggg
    28861 agagtggtga taatcaaaaa aaagttcaca gttttactca caatcatagt gaccggtatc
    28921 atgagtggtt ttgccttggt tagtataaat aaacaggtac tctatcggac aaatgaattt
    28981 ttccatcaaa cagatactta tactccgatt cgattgccac aacattttat tgggcaagaa
    29041 gaatatgagc agctaatcat ggtatttgaa aatgtctcat cagaaactga gctttcttat
    29101 atgaaaaaaa cagtaaatga atccaatgaa gtagatacat cttggaactt caagatacag
    29161 ccaaagcttg aaatgacatt gtattatcaa ggggatgtca aatcttctca cgagaaggta
    29221 ccctattcta atacctcctt tcgcgtaacg tccattgaag aatcgatcaa aataaaagat
    29281 tttgaaggtg aatttttctt gatgacgaga gaaaaagaag cctatgaacg ggtcatttca
    29341 ctattcactg atcgattcaa tcaagcattt cacactgatt atgccactaa tatttttgaa
    29401 gactttgaaa atagctattc gtattcggtt atttcaaata cagacgtata taattatcga
    29461 gtgtatttaa ctattggatt gattctttta ttccttttgt tatcatcctt tttcttattg
    29521 atgaataaag aaatcagttt attgttgaat aatgactttt cattacatca agtattgtgg
    29581 tgtttattgg ggaaaaagaa aatcattatt acattcataa ttgcaggaat cattggtggt
    29641 tttattttta tgtattataa ggagcaattt ctttatttgt tccagatgta cgttttcttg
    29701 ttcagcggaa tatatggtat ctctttgatt tctcttttat tagttgaaaa aatcgcttcg
    29761 ttaagagaag cgttcaacta tatccaatac attcttttta catttggatt gttgttttct
    29821 cttcttttga ccgttgccaa tgtcgaatta gcaactatcg ttttttcttc ttcacagtta
    29881 gctgtttccc atgaaccacc aaaagaaatc gctggtgagg actatcatgt attttatcca
    29941 gtaaccatcg ggaaaaacca cgtggatttt atttattcca atcgttttgc atcagcagca
    30001 gatcaggaat tatatgaaac tttgaataaa aacggaagta tattagtcaa tgtatcagat
    30061 tacttgaatg aagaaaatga acagtttggc agagggataa aaataaatct gaattatctt
    30121 aagaaatttc ctttgattga tgtctctgga aggttgatcc aaataaccga aaaagaaacg
    30181 caccctgtta tattgatccc tgaacgatat agacatacag atttaaaaaa tgacctggcg
    30241 caaataacag aatattatca agaaatcagt gaaaaagaac cgaaatttct atttataaaa
    30301 aacaatcaac ccatttatac atttattcct tctatcccct ggatcgaaca ttatccggtt
    30361 gttgaaatac tgacattgaa aaacagtatg tatttggaaa gaaatattct cagcggagaa
    30421 atctatccac cgttaaagat caagataggc tctttgtcga aagaaaggtt atttgagctg
    30481 attgaagaaa gtcagttacg tgataacttg cagttatcat ttccgtatac tcagactgaa
    30541 gagatagctg tcaaagtgtt aagcagatca tttcattact tgatacagat atttttactc
    30601 actttctttt ctttcttctt gttgagctat gtcatgttat gcatatattt tgtctacaat
    30661 tgtcggaaaa tcgctatctt tcgttcaagt ggttattcgc tctttgaaac gtataaagat
    30721 ttcttcatga tgaacctcat caaatgggga acgacaagtg taatcttcct ttttcttata
    30781 gaaagagagc ctaaatatct ttttaatatt tttttcttta gcttcattga ttttattctt
    30841 tcagttgttt ttattttgtc tacagaaaag aaaagtcagt tattgctgat gaatggaggt
    30901 taacaattgg agccgttgat agtgataaaa ggtgcgaaaa aaatcattcg aaacaaaacg
    30961 attcttcatt tggatcgttt cactgcggat gctggggatc ttgtgactgt tgttggagaa
    31021 agtggagcag gtaaaagtac gttattgaat atattaggat tgaatgatca gttcagttca
    31081 ggacaattct atttgttcga tcaagagacg aaacaattaa ctgggagaga gaagcgcttg
    31141 ataaaaagaa ataccatatc ttttcttttt caagattttg ggttgattga atatgaaaca
    31201 atcgatttta atttagatat tggattgaag ttttcgaatt taaatgtttc agataagcga
    31261 acagcaaagt atgaggcatt gaaaaaagta aatataaaca agaagctaag tacgcctatc
    31321 tacacattat ctggtggtga gaagcaaaga atcgcctgtg cgagagtctt attgaagaat
    31381 agcaaaatca ttttagccga tgaaccgact gggtcattgg ataaaagaaa taaggataaa
    31441 gtagttgaaa tcttatcgca acaagcttcc caaggtacgt tagttatcgt agtcacgcat
    31501 gatccatatc tgaccaaaat aggaaacaag aagatcatgc tttaaaaatc aaaaaggaaa
    31561 ggatgtcgtt ttatgaaaaa agcagttatt atttgtgcac tagggatagg ttttgttgga
    31621 ggaaacgcta tgtcatctga agtggaagca aattcagttc acggtgaaat ctattacaaa
    31681 tctttaaagc caggagagat tcattttgat gctaaaggta atattattaa gtcaaattta
    31741 ccagtagacc gggaaatttc tagaacagca attaatcata gctctggaag atgggtttat
    31801 tatagtgata caacttgtac gagaaaaaca ggtcattcta accactatag tcgtgtctat
    31861 aatcgtcacg gtgcaaaagc gaaagttgga aactctattc gatcagcaaa tgcaacaaaa
    31921 ggagtatggg cctatgcaag tgcgacagga aatagaactg acacattctc atgttggtac
    31981 aatccaaccg gttggtatta agtatccaaa agtttatata aaatagaaaa aacatataat
    32041 gaaacagcgt taaaagttat ttttggtagt tttaatatat tcatttttag ttgtataaaa
    32101 atatatcata ataaaaacaa caaaaaaatg tctggaaaat cgaacataaa agtgtctgat
    32161 ttgaatatcc cagcagcgga agaagaaaaa caaaatcgat aacatttgtt ctaagaatta
    32221 gttacgttaa atacggaacg caagatagac ttgaaaaacg gtaacaaaag aagtagtata
    32281 ttaaggtgtg atgtgctact tgacatttat tctgctgagc gaactttctg gattgtgtag
    32341 ccttatatct attcaggacg tatcgagcag attagtaaag gtgttcttga tgattttcat
    32401 cttgaacacc tttgttttta gcaattcgca aaaaacgaaa agtaggagaa ttgataaatg
    32461 aaaaaaagat ttttagcact tgccatcgta ctaggcactg gcttattgtc aggctgtacg
    32521 aatgccggtg aaaaaacagc cgttagttat aaaggcggta caatcagcga acaagaagta
    32581 atggatagct tgaaaaaaat gcaaggagca gattccgctg tgcaacagtt gatcgtttat
    32641 caagtatttg aagataaata tggagatgac gtatcaacca aagaaatcga ttctcaatat
    32701 gatcaaacaa agaaacaatt gggtgattca tttgattcac aattgaaatc tgcaggttac
    32761 acagaacaaa cattcaaaga cagtatcaaa caaagtctag cctttcaaga aggtctaaag
    32821 aaacatatca aattgaccga tgaagattta aaaacggctt gggaatcttt ccatccagaa
    32881 gtggaagctc aaattatcca agtagcaagt gaagatgatg caaaagatgt gaagaaagct
    32941 gctgataagg gagacgattt ctctaaatta gccaaagaca agtcaactga tactacgaca
    33001 aaagaagatg gcggaaaagt gaaatttgat tccactacta caacggttcc ggcagaagtc
    33061 aaagaagcag cctttaagtt gaaagatggt caagtttctg atgtgatcac ttctaccaat
    33121 gcttcaactt atactacgga atattatgtg gttaaaatgg tgaaaaacca aaacaaaggc
    33181 aacgacatgg ataaatacaa aaaagaattg aaagaaattg caacagacac aaaattaagt
    33241 gacagtacct tccagaataa agtaattggc gaagtattga aagacgctaa tgtaaaaatc
    33301 aaagacaaag actttgaaaa tgttttgagt acattcactt cagattctag tacagcaagt
    33361 agtaaataag cggtataaat aaaaaatatg aactatttaa atcaataaaa ctgttcatct
    33421 aaatcttttt attagaacta aatcaacagt agtttaatta ctacttgatt tagttctttt
    33481 tattttaaaa atttttttta cttagaatcc agcgacccta gatatttttc tgtataatct
    33541 taaataaaga aaacaatatc aaaaaatgca cgtagaagta gataaatgga gtggttttgc
    33601 aaatttcttt tatttctaga agttattcac gtatacggat ttgtttttct cacaaataaa
    33661 aaggcaggaa gtacaatgga tcatttgtat ataaaatata ttcatcaatt ttccgttttg
    33721 gtgttaggca cactaattat agcggggatt gtcgcattta ttattcaagg ccgtgacata
    33781 ttaacagtac atcaagagtt tttcagttat gcatttggta ttcctctgat cgctataagg
    33841 tctgataaca aaaagtggaa gaaacgctat tacattctct tgctattttt gtgtttttat
    33901 ctgccaccta agatttttac tttattaggt atacaatgcc tatcattttc ttttatttcc
    33961 tatatcattg ttttaatttt cctcagtttc atagtatgga tgttttatct tgtcaaaaaa
    34021 taaatgaatg tttcatgaac agtacttcat cacagcctaa tttttttctt tatgctatcg
    34081 ttatattaaa gaaatcaatc agaagggaaa gaaagtgatg aaaaaagttt tattagtggt
    34141 aaaccccagt tcaggcggtg aacaagcaaa ggaatttgag caattagcga tagcaaaatt
    34201 ggaatcggtg tttgatgaag tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa
    34261 ctttactcgc gaagcggcta cggaagggta tcatagtgtg tttgtcatgg gcggagatgg
    34321 aacagtcaac gaaggaatca gtggaatcgc tgaacaagaa catcggccaa atttcggatt
    34381 tttcccattg ggtacggtga atgacttggc tcgagcatta gggataccgc tagaacctga
    34441 ggaagcgatc aatcattttt cgattgaatc agtcaagcca ttggatattg gaaaaataaa
    34501 tgacgactat tttatgaatg tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt
    34561 agatgcggag aagaagacga aatttggaaa actagcttat ttcatgtcag gaatcaaaca
    34621 gttagcttcc acacaatcct actcgtttca cgtagaagtt gatggaaaga aggaagaaat
    34681 tgagagcagt accttgctga taggactaac taactcagtc ggcggttttg aaacattact
    34741 tccaaatgca aaagtggatg atggtaagct ccatttggtt tatttaaaag attcttcttt
    34801 gatcgatacg cttaaaacat tgccagacct attaaaagga gtagatgaat ctacgaaaaa
    34861 tctagcctac cttacttgtg agcaattagt tgtgtcatta gctgatgagg aagaattgac
    34921 gacgaatgtt gatggagatg aaggggataa attacctgtg acaatcaaag tattgccctc
    34981 acatttacag gtttattgtt aaaatggagg ttgtgaccga ggagttggcg ggagaacacc
    35041 gcttgttcgg gataagggac tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa
    35101 aagaaattta cacctaatag aaaaattttt ccataaaaat acatatttta aatatgaaag
    35161 tacaattgga aatagattaa aacgataaaa taaaattgtc aaaacgtcag agaggatggt
    35221 ggagaatgaa tcaatgtgta aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct
    35281 tgatggtgac atccgttttt gccgatgtag agaaaacaaa cgaatcaacg caatcagaga
    35341 atcaaagttt tgacaagact actttttcag aagaatcgat tacttctgaa actacagaat
    35401 ctcaaagtga ggcttctact aataaaaggc aagaagaaaa taagacaagt gagacctcag
    35461 aagtagctga acaaacgtct gatagcagtg aagcggcact ggcaagagct gtttcagcgg
    35521 atgggtacag cgaagctgcc acaacagaag aactggcgca gcttctcgca gacgaatcag
    35581 taactaagat ccgactgatt cagcctttga ctttagacag ggaattagag atcaaacgag
    35641 atatcgttat tgattttggt ggattcgctc acaatttcgg cacacaccat atttatatca
    35701 atgagatacc tcagtcgatc gagttccaga attttaaagg aacagctgca catccaggtg
    35761 gattgacacc aaatatcgat ggaaatgcca ttatcattgc ttatatgacc gatttttggg
    35821 gaagcaaata tcattttacg ggagaaataa aatttaccgg gacacttgat ttgtatgatg
    35881 ggtccaaatt aggactgatt tacgctcctc gtgcaactgt cacattagat ggtgtttccg
    35941 gtgtgttgga tgtccaacca gtgaaggaag gactgaatgc cgctccgggt aaagcctatt
    36001 tttgtagaag ctatcaattg aatgtgatca atggtagtca actttatgga ccgtatctag
    36061 ggaaattcta cggttttcta gattcaggag atgagactgg tagtggaaaa acagcgccag
    36121 gaatccatat cttaagcggt tcaaaggtct ctcttgatta tgatcgggca gatggcgtta
    36181 gcgatgaagg agaggcagtc gatacgctac ctggtaatgt catgtttgaa gtcagtggtt
    36241 cgggaagcga attttcggta aatacaaaga tcaatattac caatgacaac aatcgcggaa
    36301 tcatccaaat gagaggttca ggatcgaaag tcactgtatc gaatggtggg aaaatcacca
    36361 tcaatacagc aactacgggc ggatttcgct tgcaaggaga ttctagtcaa atccatgtat
    36421 caagtggtgg acaaatctcg gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg
    36481 ggatgcgttt tgtaggaaaa ggcctttctt tgatcgtaga aggagccgga tcagttatcg
    36541 acatcgataa gcagagtggg cgttccagcg cagttcgttt tgagaatggt acgcaaaagc
    36601 tgacagtaac caatggaggc tcattgaggg taagaaatac aggtgatggc aaatcttacg
    36661 tgaacagact caatcaagga aatcaagcga tccaatttta tgacgcttct ggttttctag
    36721 aaagtccagg ttcagctgat tttacagtca ctggagaaaa atcaaatatc gatatacgcg
    36781 cagattccgg agcaactgta gatacaactg gagatattga tttaaatttt acggcaggtg
    36841 aaaaaactta tttagtcatg gtcgggaaaa caggggaaga taagaccggc atcatcagtg
    36901 gggatgtgtt gaatgtggac ttagaatctc ctacctattt tgatttccaa aacaaacgga
    36961 ttggaagcga gaccaatggc ataggcggct gggtattcca aggaaatgga gattcttctt
    37021 taaagatcgc ccattcagaa atcgctttat ggcgaaaaac aggcgcaaca ttcgataact
    37081 ttgaaaaaga cccggattat ttttctgata tgacagactt atcgatcaat gggaccgact
    37141 taggcaattt cgtatcaagc cctagtgcag gtttaacaaa tgaatttgct cagacaggtg
    37201 ccggaatgaa aaattataat cgaatcagtg ccaataatca gctcccgatg attgaatcct
    37261 taagagtgcc aacgaatgca gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg
    37321 tcgaggcaaa gccaagagat gcttggacag gcgaagtaga agtgacttta cgtattactt
    37381 acgcagatac gacgaaatca tctgtagaaa ttactgctct cacgcaagga caaacagatg
    37441 aaaatgaagg ggcaggatat aacccatggg gagaaggcga acaaggcggc ttgttcgaag
    37501 ttcaagtacc caatgatgag agattaaaaa cggaggatca agtgcaagtt gttgctgcta
    37561 aaaaagtaag aggtggccaa gaagtgacag aactggactc tgccaaaacg acagtcgatg
    37621 tgattcctcc tgaacctgct aatttaagta ccacattgat caatgcagct tctcgcacga
    37681 tcacaggtac aggtgaagca ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt
    37741 cagaaacaac tattgatgat acaggggaat ttgttctttc tatcccagaa aatcaacttt
    37801 ttgcaggaga tgtattagaa attgtattaa acgaccaagc aggagaagct actgctaagg
    37861 gtgtgcagaa caagccaagt accaacgatg aaattgggaa tcacaatcca agtgatacgc
    37921 cagttgttta tcatgatgcc ccgccttttg cacctgctac gaagatcgta gtagaaggtg
    37981 gtctctcatt tcttgcccct tccaaactcg attttggtca gatcaaagca actggtttga
    38041 cacaagaagc atttggccaa atggatatac aggaaaaatt atggatttat gatcagcgag
    38101 aaacgaaaaa tccgtggatc ttaacgataa aattatctca gcctttcaca aatgatgcag
    38161 gattttctat gcaggatgtc ctatatttca agaaaggaga ggagtatcaa ttagtgaatg
    38221 aagaagaact ggaaattgtc agaggacaaa attcaacgaa tgtgcaagca gattattcag
    38281 aatatttaaa taacggtcgg gcgtttaaac ttgtcttaac caaagaaaat cagatagctg
    38341 gtaattactc agcagagata acatggacat tagcagatgc gccgacagaa taaagatcaa
    38401 ggaggatgat tgatgaatcg aatatggaat aaaagtcatc gaaacaactg ctctttactt
    38461 atgatccttc tccttggatt catcctttgg cagacacctg tccatgcctc cgaattcaat
    38521 tttgcggtag attttgaatt accggctaat cagattgata agaacaaaac atatataaat
    38581 gtaaggatgg agcctgggaa aacacaggaa atcccctaca cggtctttaa ccgaacagat
    38641 aaatcagtaa cagttgagac attgatccac tccgctacga cgaattcaaa cggtgtgatc
    38701 gaatatggag aatcaaaaag taaatttgat gaaacattaa gttatgatat gaaaaactta
    38761 gcaaaaacag tgggagaaat aactgttcct cctcaaagtg cggtcactga gacactttca
    38821 ctgaaagcgc cagaaaaaga gctggctggt gtggtcgcag gagggatcac gtttcaagaa
    38881 aaaaaagaga acgtttctaa caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg
    38941 aaagcaatct tgatttgaaa tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa
    39001 gcttatgcgg atcaaagcga tggaagaaat gtgattaagg cgaatcttca aaatccaaat
    39061 gcttcttata tgttcggctt gactacatcg gttgaaatct acaaaaaaga aacaaaagag
    39121 ccttaccttt caataaaaaa agaaaaaata gatgtagcac ccaatacaaa ttttgattta
    39181 cttgtcccat tagaaggaaa aaaattagct ccgggacatt atcaagcggt tgtgaagggt
    39241 gcttggaaag aaaaacgctg gaatctccat accgattttg aaataactga tgatgcagcg
    39301 gaccaattga atgaaaagga tattgattta aaaaatcagc cagaaacatt tgactggcga
    39361 tggctgatac ttgttggagt cattcttatt ggcttatttg ctggattatt tattttaaaa
    39421 gaaagaagga aaaagaaatg aaaaaaacaa ttgcattaag taccgttcta gctggaagtc
    39481 tattattatg tacacaaagt gtttttgctg agaataagag ctcagccact acagaaggaa
    39541 cgatttctgt gaccaaacca gatgctgcaa atcctgaaga cgttgttcca gttcctcctg
    39601 ttgatccaaa tgatcctgat actcctttta cacctgacga accaaatcag ggaacatccg
    39661 gattactgac gattgaccaa gctccagatc ttgattttgg aacaatcaag ttaggtacag
    39721 caaaaacagt atatgctgca ttacaaagcg gaacggacag tactggagca caaacacaag
    39781 tacagaattt cgtacaagta acggataaaa gcggaaatta tgccggttgg aaattatcag
    39841 tcaaacgaac agaatttatt ggtacaacat ctgatacgaa taaactaact ggttcaaagg
    39901 tgaaattcaa aaacgccgtg attcgaaata gcgcaactaa tagcagtgga atgccatcta
    39961 ccgtttctgg aactggcgct gaaggaatcg aaatcccagc agatcaggca gtagatctag
    40021 taactgcagg agcaaatgaa gggattggca catggattta ttcattagga gagaatgtgg
    40081 aacaagggag acaatcagtg gaattatttg ttcctgtatc caattatgct gtagacaact
    40141 acgtttcaac attcacatgg tcgttaacag atgctcctac agaagaggaa gcgtaaaatc
    40201 atatcaacga cttcagggag tggagccgat tcaaggccca ctccctgaaa tctgctatgc
    40261 ttacgtctca gctcttattc atcaactcga agcagttttt tggaagtcat ggaaacgttc
    40321 ctttgtcttt tcaaagatct ttcgaccaac gagtaaggag tcaccgttga aaaattctaa
    40381 cacataatga gcagaatcaa ttttctgcaa ttgcgataag ttgatacagt aagattttaa
    40441 aagtaaaaag taagcatact tttctaactc tgtcttcaat tgttttaaag aagtattcac
    40501 taatttatct tctgtagttg ttttgaccat aacttggttt ttcaaacctt tgatactttc
    40561 aatatataaa atttcccgag gatacaggac gagacttcca cctttttgat caataaagat
    40621 tttatcgaca tttacgatct gctgttcttt ccaattgatc tgttctagca cttgacgaat
    40681 ttgttcagat aaattcctgt cttttctgat atatccaatc ggaaggattt tccgattgat
    40741 gatctctact gcaaaattcg tataagcggt gaaaaaaaca atattactat gtgcattttt
    40801 tttacgtatt tgttcggcga catcaatacc tgtgagtgat tgcttcaagt cgatatcgat
    40861 aaagaaaaca tcgtgattat caatagtgcc caactggatc aactgattga tttgagagat
    40921 agaagtgagc tgcacgatat tctcgatatg atgattgacc aattctctga tgatccattc
    40981 gctgtgaaac tggttatctt ctatgataaa atactttttc atatgcaggc tcctattaaa
    41041 aaaatatgtg tacattttga aacaaaacaa tggaggaata agatggtcgc aacagtgaca
    41101 ctttatttga cctttacttt gattttagat ttaggtatct atttattctt ttcgaaacaa
    41161 ctgctagtaa aaaacagctt tggttgtata gctttgatgg tggtgacact tttacttcct
    41221 atccctaaag tgagctttcc ttacctaatt ggcttattat tgatgtttct tttttatttt
    41281 actacgaaaa acctgtttat cagctgtttg atcagtaatc ttttttttgc tatcactgga
    41341 ctcagctttt ttctggtttt tgatctgatg gattatttag gaaagagaca tcttggaaca
    41401 gcaagttttt ttgcactact tatcgcattt attttctatc tattagtaaa aagtatagac
    41461 aaacagacga gatttctcaa cttgcttttt acttatccaa ctgaacacta ttttggaggt
    41521 atttgtattt tattaagctg gggcgtgatt tacttggtat tgggaagtgt tcacttccgc
    41581 tcatctaatt atctgcttct atctcttttg tcgatagtca tcagtttttt ttctttgttt
    41641 ttttccatta tgttgatcag tttccaagta aaagaaagac aacatcagga atcgcttcaa
    41701 ctgtatcaaa taaatgaaga atattaccat catctagagg aattcaaaca tgattataaa
    41761 agtctactgt tttcattaaa aattactctt caggaaaata aaaaagaaac gttggaattt
    41821 ttagaaatat tagaagatca ttctgcagct atttttgaaa aaccgcaaat acaacagcta
    41881 acaaatattg tatccccagc tgtcaggggt gtctttttaa aatttctaga aaaagcagaa
    41941 tcggagaaaa tcccgatcca agtagttatt cctgtcgaag tgaaaacaat cccgattgat
    42001 ctggttgttt ttattcgctg tttatctatt tttatttcta acgcattcga tcatcgtgta
    42061 gccgatcaga gtccgattac gatcaatctg ctggaagaaa aagagggatc acgttttagt
    42121 atagcgaaca aggcaaatcc aacgaatttg acgctatcgg agatggtcaa aagaggaaaa
    42181 acctctaaaa aaaatggcgg gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac
    42241 gaaaatgcag aactaaaaat cgaattttca aaacagaatc actatttttt tgtagaaatg
    42301 tatctggcat ctagaaagag caaatcagcc tactgactta ctgtcaaagg ataagtttga
    42361 ggaaagtcta cacggagata gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg
    42421 atgaccgttg tcacccttct gtttcttttg ctatgtagtt aaacaaagta gttgacactt
    42481 ccgctactta gtattagtac gaaagtatac ttcatgatac taagtagata agaagtgaaa
    42541 agcggaaccc acgatcgtca aaatgctaac tgctttgctt acaccagata aagggaagag
    42601 caatatcgct tattttaggc gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg
    42661 ctgacccagc agttaagaga gttagaacaa gatgaaagta tccatcgaaa agcctataac
    42721 caagtcccgc ctaaagtaga gtactcgctc accgaagaag gaaaatcatt aagagagatt
    42781 ctagtagcgt tgtctgtttg ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa
    42841 gaagacacgc tactgcatac acatggtggc tacctaaatt attgattttc tatgacattt
    42901 attttaaata aaagaaaaca ggagtttttt taaaagcatc atctattttt tatgtaaaaa
    42961 aatggtatga ttaatcaagt aagaagtgat tggaagaagg caagcaaatg aatagtatgg
    43021 aaaaagtcaa ccagtttaga gatgaacgta attggcgaca atttcataac gaaaaagatt
    43081 tggctatctc tatttctttg gaagcatctg aattgttaga actttttcaa tggaaaacgc
    43141 cggaagaagt aaaagaaaca caattagaac gaatcaaaga agaactggca gatgtattga
    43201 tctattcata catgatggca gacaaccttc acctggatct agatgagatc attgaagaaa
    43261 aattgatcaa aaataatttg aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat
    43321 acacagagtt gtagaaatgt gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa
    43381 atgagtctgg agggagagaa aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat
    43441 atcctcttgt tcctcttgtt attagtagga ctagctttga ttttcaatga acagatcaag
    43501 gattattttg tcagagagac aggagataaa tatgctatag cgaatgtaac aaaagaagat
    43561 ctgaaaaaga ataacgataa agatgtcagt tttgactttg atgcggtaga accaatgacg
    43621 acagaagggg tcatgaggtc gcaaatgaga ggaacagatc taccagtgat tgctagtatc
    43681 gcagtccctt cagtttcaat caatttaccg gttttcaaag gcttggataa tacgtcacta
    43741 ctttacggag caggaacatt atctccagat caagaaatgg gaaaaggaaa ttatgcctta
    43801 gcaagccatc gtgcaacgaa ccctgaattg ctgtttacac cgctagaaaa tttagagatg
    43861 ggtgccaaga tctatttgac agatttagaa aatgtgtata catacaaaac attttttaaa
    43921 gaaaaagttg ctcctacaga tacccaatta ctgaatgaag tcgagggaaa agaaattgtc
    43981 acactaatta cttgtggcga catggacgcc gtcacgcgac tagttgtaca aggagaactg
    44041 gaaagtgtta catcgataaa agatgcgaca gatgatatga gatctgcttt caatctagag
    44101 acaaaaacat tttaggatac tgggacataa gtcgttacag attaaaaaca gccaaaggat
    44161 atgaatcgat aaggaaaaac caatttgctg aaaaaaagag aaacgcaaag aggtgcatct
    44221 ctgatttggt tgttttctag atagacttgt gttccagttt ttttattttt tatatgaaaa
    44281 ggtttgcata aataaaaatt cgatggtatg atgattttga ataagaaatg gattgttact
    44341 gtacggcagg caaaaccaga attcagctaa gaaacagtag gcgaattcta ggttttttta
    44401 tttttcttga gagggcgaag caaaatgaaa attgataaaa ttttgaataa caatgtcgtc
    44461 atttcgaaaa atggattcgg ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa
    44521 aaaaagattg gggacgagat ttcgccagaa gcggtccaaa aagaatttgt tttaagagat
    44581 tcttttgcta aaaaccaatt ccagcagctg atggctgata ttccggcaga ggagatcgaa
    44641 tgggtcaaac aagtagtcga actggctgaa gataaactaa aagttgaatt ttcgcctaat
    44701 atttatctga cattgaccga tcatcttcat tatgcgatca cacgagcaaa agaaaatatc
    44761 caactgccta atccattatt atttgaaaca aaaaaatttt atccgaaaga atatcaagca
    44821 gcgaaagagg ctcttttgtt cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa
    44881 gccggtttta ttgcctttca ttttgtgaat agccaacaag gaaacgaaga catgcaagtg
    44941 acgatgaccg ctaccacaat ggtaagagat atactgagta tcatcagtaa attcttcggc
    45001 atcgtgttcg atgaagaatc tttgaattat cagcgtatca ttactcatct gcagtttttt
    45061 gcccagcgtt atctcaaagg ggaaggatct gacgagcaag atgaatttct ctacgcatta
    45121 gttcaaggaa agtatccaaa agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga
    45181 caaacgcaaa aacaggaaat ggggatcgca gagcagattt atttaacgat tcatattcaa
    45241 agagtagtaa gtgagaaaaa aagcatccaa tcataaggat tgttactgta tggcaggcaa
    45301 aacctggatt gaaaaaatag gttcacgaat gtttgtgact gtttttttca atctgggttt
    45361 ttatttttta aataaaaaag aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt
    45421 cgtgtatggg aagcggtagg aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg
    45481 cggttgcgat tcagattaaa agatgaatct ttagcagata cgcaaaagtt aaaagaagac
    45541 ccggacgtga tccaagtcgt acaaagtggc ggtcagtatc aagtagtgat tggcagtaat
    45601 gtagcagatg tttatcaatc gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga
    45661 aaagaagagt ccaaaaatat tttgaatcgt ctgatcgata ttatctctag tatatttaca
    45721 ccttttctag gggcgatggc agccgccggg gtattgaaag gattcttatc attggcaacg
    45781 gtgatgggct ggctgacagc tgatagcggt acttatcaaa tattgtttgc tgcagcagat
    45841 ggtgtcttta ccttcttacc tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc
    45901 aaccagtttt tagcagtagc aattgctatg gcacttgtgt atccagctat cacagcagtt
    45961 gctggtgcgg gagaagctat cagtttcttt gggatcccag tgattctttc accatctggt
    46021 tatacttctt ctgtcatacc aatcattcta gccgtatggg ttcaaagtaa attagagcca
    46081 ttcgtaaaaa aagtgattcc gcaatttctg caaatgattt tagttccgct tgtcgtttta
    46141 gtagtgatgg ttccattaac atttcttgct ttaggaccaa tcgggacggt tgccggtaat
    46201 gctttaggcg gtctcttcaa ctcgatttat ggatttagtc caatcgtagc aggtctaatc
    46261 atgggaagtt tatggcaagt attcgtgatg ttcggcatgc attggggatt cgtaccgatc
    46321 atgtttttga atatcgaaca atatgggttt gatgtattga tgccaatgct tcttccagcc
    46381 atcttggcac aaggtggggc tgctttagct gtagcattgc gaacaaaaga tacgaaactt
    46441 cgagcattag ggatttcttc tacagtgact tcgttatttg gaatcactga accaactgtg
    46501 tatggtgtga cattaccttt gaagaaacca ttcattgccg cttgtatttc tggaggtatt
    46561 ggtggagcta ttatcggatt ttccggagta aaagctttct ccagcagttt ggtcagctta
    46621 ttgacgattc cgactttcat taatacggtg gatggtgtag agtcaaatgt gacagtagca
    46681 gtaatagcta caggaattgc ttttgttctt gcattcgtag gtacattgat tttaggattt
    46741 gacgaacaaa cacaagacaa tcaattagaa aacaaacatg cgaatgcagg agaaccgatt
    46801 acttcagcac ggcatacctt aaaaagtcct ttaacgggta aagtactgcc attgagtgaa
    46861 gtaccagacc aagttttttc ttctggcgtg atgggaaaag gtatcgctat tgatccagaa
    46921 gtaggagaac tagttgcacc tgcagacgga gagatcacga ctatttttcc aactggacat
    46981 gctgtaggga tcacaacgac tgacggagcg gagattttga ttcatatcgg gatggataca
    47041 gtagaattaa atgggaatgg ctttgagatc ttagtcaaac aaggggatct cgtcaaagca
    47101 ggagatttat tgattcgttt tgacatcgaa gcaattagag cagctggcta tagcgtaatc
    47161 actccagttg tcattacgaa tactgatgca tttgccgata tacttgaatt agaccaaaaa
    47221 gagattattg caaacgaaga tgttctggca attgtaaaat aaggaggaaa tcaggatgca
    47281 atcacgtttt tcagaaaaat ttttatgggg tggagcaact gctgccaatc aattagaagg
    47341 ggcttatgat cgagacggaa aagggctatc cgttgcagat gctatgcctg gaggtaagca
    47401 gcgctttgcg attatcggca gtgaagaatt tgactggacg attgatcaag aaaaatatat
    47461 ttacccgaat catcgaggaa ttgatcatta cgatcgtttc aaagaagatc ttgccttgtt
    47521 tgcggaaatg ggattcaaat gttatcgttt ttcgattgcc tggacacgaa tttttccaaa
    47581 tggagacgaa ggtactccta acgaagcggg attagaattt tatgatcagc tgattgatga
    47641 gtgcttaaaa tatgatattg aacctgtgat cacgatttct cattacgaaa tgcctcttca
    47701 tttggcaaaa gaatacggtg gctggaaaaa tcgaaaactg atcgacttct atgaacgatt
    47761 tgctcagaca gtattagaga gatacagcag taaagtcaaa tattggatga ctttcaatga
    47821 aatcaattcg gcctttcact ttccagcttt aagtcaagga ttagtaaaaa gcaatggagc
    47881 aggagagtac caaaatattt tccaagcatg gcataatcaa ttcgttgcaa gtagcaaagc
    47941 cgtaaaaatc ggccacgaat tgcgttcgga tatccaaatc ggctgcatga ttatctatgc
    48001 aacaacttac agcatcgatg ccaatccagt caatcaggca gcaacaatga tccaaaacca
    48061 agaattcaat tttttctgca cggatgtcca agtacgtgga gaataccctg catacacagc
    48121 gcgtacccat aaaaaatatg gagtcgatcc ggaaaaatta gagcaaacgg aaaaagactt
    48181 ccagttgcta aaagaatatc cagtggacta catcggattt agttattata tgtctacggc
    48241 aatcaatgag actgatccac aagcagcaac ttcagaaggg aacttgctgg gaggagtaaa
    48301 aaatccgttt cttgaggcaa gtgaatgggg ctggcagatc gatccagaag ggctgagaat
    48361 cgcattgaat gaattataca atcgttacca gaaaccatta ttcattgttg aaaacggtct
    48421 tggagccatt gatcatatgg aagaggatgg cacgattatt gatgattatc ggatcgatta
    48481 tttacgtcgt catatcgaag cgatggctaa tgcagtagca gacggtgtag atttgatggg
    48541 ctatacgcct tggggatgta tggatcttgt cagtgcatca acaggagaaa tgagtaaacg
    48601 ttacggcttt atctatgtgg atctagacga tgaaggaaat gggacactga atcgatcaaa
    48661 gaaaaaatct tttgattggt ataaagaagt aattgcctca aatggcgtaa acttgtaatt
    48721 aaagcagctg aatgaaaaag aacacacttc tcacatgtga tttgtgttct ttttttattt
    48781 tttatgtgct attcttttag taatagtaaa gcaaagggtg acgttatgaa aaggacacgt
    48841 gtactatact tggaagtcgc agataaaatt aaagaagata ttttctcagg aaaatatcca
    48901 gtcggttcga tgttaccgac agaaagtgaa ttagaagaac tgtttcaagt cagcaaaatc
    48961 actgtccgaa aggcaatcga actgctggca tcagatgaat atgtcgcaaa gaaaagtggt
    49021 cgtgggacga cggttctaag caatcgtcct tacaatcgat tatccaaagc ggcaagcttt
    49081 acgcaaatct tggagaactc ccgatatgaa gtccggaaag aaacgctgga tttgcaattg
    49141 gtccatataa agaaggaaga tcctttgttt tcctttttcg gtgagcaagc tgtttgtttt
    49201 aagcgcttat attatttgaa caatcagcct tatatttatt ttgttcatta tcttccacaa
    49261 gaaatgatgc aattcagcag agaagaattt ggcaaagaat ctttgtatcg tttgctgacg
    49321 aaaaaaggat atactattga ctcattttct gatgatttct cggcagtatt tttaacagaa
    49381 gaagaacaag aaattctgaa aacagacgca cagatcggca tcaaacggat acggaaatcg
    49441 tctacgcaaa ttggggaaat gattgaatat tcggaggcgg tctaccatac ggagctgcat
    49501 ccttaccata ttgattatga aacataaata aaaaaagagg ttgtgaaaaa gctgccctgc
    49561 atcaagtaat aagaacagcc aaacaaaaat agcttctcat attagcttct catatttttc
    49621 gtttggttag gcttattacc gcagataccc ggctgtttct ggattaccat ttattctgga
    49681 taagggggtg tggcacgatt ttcagaagga atctatgaac caatcactgt attgatttta
    49741 gcttcgatgg taaccccatt cggcttgacg atcgcttatt tcttagggaa aatcattcgt
    49801 aaaaatatat tcaatcgtca agaaatcgat acattgaaga ccgcttttcc tatggggatc
    49861 tgtcagatca cagagggatg tttccctatc gtattgaacg acttggcacg caatgtcata
    49921 gcaacgggag tcggtggggc agtcggcggt ggattgagca tgttttgggg cgcagatagc
    49981 cgtattccgg catcgggaat gtttgcagtc gctacgatga ccagaccatg ggcattcatt
    50041 ggtgcattgt tagctggttc ttttgctacg ggaataacta ttttattatt gaaaaaacca
    50101 gttgacccaa atgcagaagt catccaagaa gaaaaagagg aagaagagat atcttgggat
    50161 gacttgacaa tcagttagga ggaacagaat ggattacaag aaaagagtac aacaaatgtt
    50221 cctagattca ggagtagtat tgaaagaaac agaattagaa agaatcgaat atacagattt
    50281 tggattagga gcaatcgaga ctgaaggatt gaatttattt gtttatgaaa ataatgagcg
    50341 atactgtggg aaagaactgg tattattgcc ttatcaaact tgtccagagc atcggcaccc
    50401 acctcgagat gagaatgaag gaaaaaagga aacctttcgt tgtcgaaaag gcttagtata
    50461 tctttatgtc gaaggaaaag aaacaaaaaa actttcctgt attattccaa aggggcaaga
    50521 acgttactat acggcaaaaa aagaaatcat acttcacgct ggagatcagt acacgatcga
    50581 acaaaatatt aaacactggt tccaggcagg tgcaacaggc gcggttatca ccgaattttc
    50641 ttccagcagt gatgatccaa gtgatagttt tacgaatcca gctatttatc gttaatacaa
    50701 aggtttggga acaagctgat gaaccaaaat gatcaaattt cgattatttg gttcgtcggc
    50761 ttttttattt agagaaacat caggcgttgg tgaaacataa cacgagaata aaatggattt
    50821 ttcattaata ggagaaacaa gtgtgtgact atttaaataa tgcgtgttat tgacatgcag
    50881 gacgaaatcc caatttcttc tataagtaag tcgtttcaat tttatattta ctagttattt
    50941 atttttttgg ttactgtaaa atagctgaaa aattattttt ttgcaaatac tatatatagt
    51001 ggtgtttgat ctatatacca ctaaaaaact acaaaatcta gtcttttatt ttaaaaaaac
    51061 acgtgtagaa tgaagataga cttttgagtt agggagtgtt tttttatgaa acttactgtt
    51121 ttttgcggtt cccgttttgg caataaagaa agttacaaat ttattgcgca aacgttagga
    51181 aaatatatgg cacaagaaga aatcgaactg gtttacggtg gttcatactc cgggattatg
    51241 ggagtgatta gtaaaacagt actggaaaat aacggaaaag tcacaggtat ctatccaaat
    51301 ggcctttttg aaactgagct gcctgggaaa gatgttacta catttattcc tacagagaca
    51361 attgatgaaa gaaaggtatt attatttgaa aaaggagatg ctgtcctcgt tttccctgga
    51421 ggtctaggta cattggagga attttcgcaa cttctttctt ggatagcgat cggcctgaca
    51481 cctgataagc caatcggaat attgaatatt ggcggttatt acagcggctt gcaacaatta
    51541 ttagaaactt ttgcaaaaga ggattttatg gataaaaaat ggttggatca agtgatcttt
    51601 tccaacaatc cattggaact ggtcaatgaa ttacgagcag tatctattaa aaatcagtta
    51661 ttattgaagg aggcaaaata atgagtcaaa tatatttagc aggaccattt ttttcagagg
    51721 agcaaatcga tcgagtaagt cgtatcgaaa aagcgttgga ggaaaacaaa acagtcacaa
    51781 gtttctactc tccacgtcat caccaagaaa gcaattatga actattcagc gctggatggg
    51841 cgcaggaagt atacgaaaaa gatatggaag agttgacaaa tgcagaattt gttttggcta
    51901 tccttgactt tgagcatcaa acaatcgatc caggaacggc ttacgaatta ggtgtggcaa
    51961 ctatgttgaa aaaaccgatg atcatcgtac aagaagagac ggtacctacg aacttgatga
    52021 ttacacaaag tcttcacacg tatttaaaat cagaccaagc tgtacgtgaa tatgattttg
    52081 aaaaattgcc tgttgaaact tacgtaggcg agtacttata gaagaggaag ggttgtatgt
    52141 cagtgatttt gatttcagga acgattggtg caggtaagag cagtttgacg gatatgcttg
    52201 caaaagagat tgattctaaa ccattttatg aaaatgtcga agataacgaa gtattgccgc
    52261 ttttttattc aaatcctgag cagtacgcat ttttattgca aatcttcttt ttgaataagc
    52321 gatttttagc aatgaaaaat gctttagtga acgatgacaa tgtgctagac cgctccatct
    52381 acgaagatag tctgttgttc catctaaatg ctgatttagg tcgggtaacg gatatcgaag
    52441 tacagcagta cgatagctta ttagatacga tgctaaacga gttagatgat gttgctccaa
    52501 aaaaacgtcc tgatttgatg gtccatatca aagtttcttt ggacacgatg ctagaacgta
    52561 tcaaaaaacg cgggcgtgac tatgaacagc tagaaagcga tgaaacgtta tacacctatt
    52621 acgaaacact gaacacccgc tataatcaat ggtatgagga ttttgatgta tgtcctaaaa
    52681 tacaagtgga tggggataca ttcgattttg tagaaaatcc agaagatgca aaaaaggtga
    52741 ttcgtcagat ccaagaaaaa ttagctgaat tggaaggaaa gcctgctgga aaatatttta
    52801 cagataatca gcatgcgaaa ggtcaagaat taggctaaaa gtaaaaaacc aaacgacggg
    52861 aaagaaaaat tactacgtga tgtagaataa gtctttctat cgtttggtta ttttatattc
    52921 aaagatgtga aataaataaa acgttactct ttgatttgtg aactgaaatg atccactgtt
    52981 tgttttactg attccagttt ttgaagcttg atcaaaggaa gaagctgagt ttgaagttca
    53041 taaaaatcag ccatagtgag ttttgcttga ttttgcttat cttcttttgc tttttacata
    53101 atttttgaca ggataagatt caaacgattt aaaagaatct ttgactagtt tgtggcaatt
    53161 gtcgcatata ctcaaacttc cttgatcatt aaattctgta tggatatttt tgttgttatt
    53221 acatgtacaa taatcaggac tatcgatcat ccatttcgtc tcctttacag tcatcttgct
    53281 tctttactat agcagaaaag aaggggagaa acaaaagaag atccaacaga tggcactata
    53341 gactgtagat gttgccatcc ttatccttca aacggtaatt accgattttg gtaaatgtga
    53401 ctgttgcttc ttttttattt tcttttcctg aaataatata ttcgtcatct ttggtagtaa
    53461 tcttgatatc tgtcagcact gttttttctt cagatgattc agaagaatca gctccttgtg
    53521 tctgatacgt gcgtgtccat tccatttttt tatctgtaaa tgtcaactgt cccgcggata
    53581 aatccatatc tttacgtact tttagcgtat atacactgtt ggtgatatct gctttttccg
    53641 cttttaagac agaagaatcg gttgtttcgt ccgaggattg gtcagagccg ccaaacaaat
    53701 cacagccagt caatgtcaaa agtcccgcag acaaaataaa tagtacgatt aatttcttca
    53761 aaatacttcc cccatttgat aggataaaga aattatacca ttggaaagta aaacttcaaa
    53821 cggatggaag agaaaaaatt cacaaaatac cattaaatag aataattttt caaaagtcat
    53881 aaaaaatcca ccacctttag aaagcgtttt aaaaaaatgt gttgcaatct ttaaaaaaag
    53941 tgctatatta aaaatgaacc ggttcaattt tagaatctag gagatgaaat aatgaaagtc
    54001 gtagacagac tatctgaaaa aatgctacca atcgtatcta agatgagtag ccagcgacac
    54061 ttgctggcca ttcgagacag ttttatcgtt actatgccgt tagtaatggc tgcttctgtc
    54121 atggttttgc tgaatgctct gattttttca aatgcaacag tccaaagaat acttgatcta
    54181 agtccattgg ctgaacttgc ttcaatcgtg aataatggta cgatgagtat tttagctatt
    54241 atcgtgtgtt acaatatcgg ctggaatttg gcaacccact atatccaaac aggcgtgatt
    54301 gatgatccat catttagtcc tgttcatgca ggaattctaa gtacagccgt aatgtttatt
    54361 ttgatgtctt tatcaagtac agtcactttg atggacggaa atacagcaga agctacaggg
    54421 gttttcttac aaagtctgac ttcttcgtct ggcttagcaa cggcgatgat tgctgccctt
    54481 gtcagtacag aattatttat caaattagcg aaaatgaaga gttttaaaat caggatgcca
    54541 gaaggagttc caccggcagt agctgcgtca tttaattctt tagtaccaga aatagttgtc
    54601 attttatttt tttcagttgt cgtttttact ttaaaccata cgactggttt gaatgttccg
    54661 caattaattg aattagcgat tcagacacca ttgaaagctt ttgttttatc cgtcccaggc
    54721 atcttatttt tacagttttt ctctgatttc ttatgggtgt ttggtatgca tggttcgagt
    54781 attttggctc ctatacggca agcacctttg ttacagtcta ttcaggaaaa catggatgct
    54841 ttttcagtag gaaaagaaat tcctaatatt attacggagc cctttaccaa tgcatttgga
    54901 ttgatcggag gtggcgggtg tattttaccg ttagttattg ctatcttgtg ggcttctaaa
    54961 cgtcaagaac agcgatcaat cgctaaattt ggtctgacta cttgtttatt taatattacg
    55021 gaaccaatta tgtttggatt accagtagtc atgaatccaa tatatatgat tccatgcgct
    55081 attataccat ctattaactt ggttattgcc tacgcagcca caagtcttgg aatcatcagt
    55141 aaaacagttg ctgctgcacc ttggatcact ccaccggtta tacaatcttt tattgctaca
    55201 ggaggcgata tacgagcagc agtcttaaca gtaatactta tcattctaga tgtattttta
    55261 ttcctgccat ttgtattagc cgctaataag gcaaaattgg cagaaggagg atattaaggt
    55321 gtacgattac ccgtatcaaa acccaaagtt aaccatccgc caaagagtag aagatttact
    55381 ttcgaggatg aatattgctg aaaaagtagg acaggtaaac cagcatttgt atggttggga
    55441 atgttatgaa aaaaacggag acaagatcga attaacagaa aagttaaaag aacatgttaa
    55501 atggggaggc ggtctgggtg ccttatacgg tctgtttcgc tctgatccgt ggtctaaaac
    55561 agattataag aatgggattc ctgcaaaaga aagctggaag gtggctaacc tagtccaaga
    55621 atatgtacta cagcattcgc gatggaaaat tccagttttg cttgtagaag aatgtccaca
    55681 tggtcatcaa ggcttggatg ggatttctta tccaacgaat atcggccgtg gaaatacttt
    55741 caatgtagca ttattagaac aatcgagtcg attgatggca aaagaactgg ctgctaaagg
    55801 tgttcattta gcgctggtgt cgactttgga tctggcaaaa gatcctcgtt ggggaaggac
    55861 agaagagtgc tttggggaag atccgattct ctcagctcgt ttttctgaag cggtcgttcg
    55921 agggttccaa ggagagatta tttcagaaaa agtttctttt cttgatcaga cagtagagga
    55981 aatcaataag aagaaggatc agatcggtgt tgtgttaaag cactgtatcg cacaaggaga
    56041 agctttaggc ggtcataatt caggcacagt aacgattgga cgcagagagt tctccgatat
    56101 ttacggacca ttattgaaga gtacaagaaa tgcagtaggt gtcatggctg cttataatga
    56161 catcgacggg ataccttgtc atatcaatcg agcgcttttt gagcaaacat taagaaaaga
    56221 gatcggttat caaggaatcg ttatggcaga cggtgtggct ttggatcgtt tatccgatgt
    56281 ttttacagat aaaaagactg ctgcagcata tgcattagcg gcaggaatcg atctcagttt
    56341 gtgggatgag acctatacca agattgcaga agccattgat aatcaagtcg tagatgaaaa
    56401 gctactagat caagcagttc gccgagtttt atctgtcaaa tttttattag gtttatttga
    56461 acagccattt gcaaacgatc caaaggagta ttgggatcat ctcatggagg aatcagagca
    56521 cttaaattta gagacagcaa aagaaagtat cactttacta aaaaatgacg gtatattgcc
    56581 gttggatcaa caagtaaaaa acattgctgt tataggtcca aatgctcacg atgtttacca
    56641 cttgttggga gactactctg caccacaaac agaagaccgt ttgaaaaaaa agatagtaca
    56701 agagataaaa acagagtttc cccaatcaaa ggtttcttat gcacaaggat gtgaagtaag
    56761 aaatcaggag gatcaggaag aaaaattatt agaagcggtg acccttgctc aaaactcaga
    56821 tgtgatcatt gcagttctag gtggatcaag tgcgcggaac tttgatatgg aatttcttcg
    56881 taacggggca gtttcatcga aagggatcaa catggattct ggagaaaatg tagatgttgc
    56941 ttctctttct ttaggtggat accaagaaca gctgattgaa caattgtatc aactaggcaa
    57001 gccaatcatc acgatacttg tgcaaggaag accctacgat ttgatgaaaa tcgagtcatt
    57061 tacgaatgcc attgcaacag catggtttcc tggacaggag ggtggaaaag ccattgcgca
    57121 gatgatttct ggaagaaata acccaagcgg acgattgagt ttgtcttatc ctagaaatag
    57181 tcggcaacta cctgtttatt actatcagcg tgctgcttct aaacaagaga attattatga
    57241 tttaagcgga agtccatttt atccttttgg acatggtcta agctatacaa catttgaata
    57301 cagtcagatg gaagtcaaaa cggatattga caaagtaata atatcaatta aagttaaaaa
    57361 tacaggaagt gtttcaggta aaacaagtac tcttgtctat gtccgattaa ttgacggcgt
    57421 tgtcatccaa agaacgaaat tattgaaagc ttttcgtaaa gatgaattgc ggtctcaaga
    57481 ggaaagactg cttgtttttg aactcacttc tgaagacttt agttatatgg atattgatga
    57541 caagcggcat tatgcaaaga aagcggtcat catggtcgaa caacaagaaa aagaaatcaa
    57601 atgtaactgg caggagtgaa aatgtatggc atcgatccgt gacgtggcta agatggctgg
    57661 tgtttcagtg ggaacagttt cccgctattt aaacggtcag cagctgaagg aaaagaatat
    57721 ggaaaaaata tcagaagcga tttcagcgtt ggactataaa gaaaacatca ttgctaaagg
    57781 attgaagaat aatcgaagtt tctctattgg actgttgata aacgggatat ctaaccgatt
    57841 tggttcggag gttgtttcag ggatcgaaag agtagctgaa gaaaatgggt atagcttatt
    57901 attaagcggg tttgccgatc agccagaaaa aatcgaacaa aaaatcgaat acctgatgaa
    57961 gcatgcgatc gatggattga tcgtcttctt atcagaagaa gagtggtctg gatttgaaat
    58021 gctgacaaaa atgagtatcc cagttgtcgc attgaattgt ccgggtgggc cagcaggtat
    58081 tgatacaata gtagtgaatg atcgagaaag tgtagcaaaa gtgattgctc atcatggcgg
    58141 acaaggacat aaaacaatag gatttattgc tgccgctcaa acagattacg tagcaagaga
    58201 acgtttagct ggagccaaag aagcggtaca aaaggatccg tctatccatt tagagatctt
    58261 tacaggagac tattctagaa aaagcggcta ttacggggca aaagcattat tagaaaaagg
    58321 ggcaactgct atttttgtca gcaattacaa catgtcgatt ggtgccatcg aatgtttcaa
    58381 tcaagaaggt gtcagaatcg ggaaggatat tgcgttcagt cactatgatt atttagataa
    58441 aaacgatctg agtatccttc caaaaatcac gatcacgcca ccaacagata aaatcgggga
    58501 acgagcagca gaacagctgt tgaaacgaat caaaaaagaa gaggaagaaa atgaaaaagt
    58561 gattgtgatg gaaaatatca tacatggaat caactaaaaa agaaaaagag gtgctttgat
    58621 gaaaagatat caatttccaa aaaatttttg gtggggctct gcagcaagtg gtccacaaac
    58681 agaaggaaga atttcaggcg atggaaaagg agagaatatt tttgattatt ggtacaaaaa
    58741 cgaaccgcaa aagttctttg atcaagtagg acctgaaaaa acctcgcaag tttatacgaa
    58801 gtatcaagag gatgtacagt tgatgaaaca gactgggcat aattcatttc gaacctctat
    58861 ccaatggagc cgtttgatac ctgatgaatc tggaacaatc aacgaagaag ccgttcgttt
    58921 ctatcatcac tattttgatg agttgattga aaacggtatc gaaccctttg ttaatctgta
    58981 tcatttcgat atgccgatgt atctgcaaga aaaaggcgga tggttgaacc gagaaacggt
    59041 tgaagcctat gaaaaatacg caaaaagttg ttttcaattg tttggctcga aagtaaaaaa
    59101 atggtttacc cataatgaac caatcgttcc agtcgaggca ggctatttgt atcgatggca
    59161 ttatccggaa gaatcagata tgaaaaaggc aatccaagtt ggttatcatg aagcgttggc
    59221 ttcagcatta gccatcaaag cttaccatga aatggatcaa agcggtgtga tcggaatcat
    59281 cttaaatttg acaccgagtt atccaagaga cgaatcaaat cccgaagatg ttaaagcagc
    59341 acgaatagca gatgcgttct tcaatcgttc attccttgat ccagctgtaa aaggcgagtt
    59401 tcccagtgaa ttgattgaga gaataaaaga actcgatcta atgccggaga ttcatccaga
    59461 tgatttgacg atcattaaag aaaacacagt agatcttttg ggaattaatt attaccaacc
    59521 acgccgaata aaagcaaaag aaacaccaat cgatactaaa aacggtccta tgcctgagga
    59581 ttacttcgac aattatgaaa tgcctggtcg taaaatgaat ccttatcgcg gatgggagat
    59641 ctatgaaaaa ggaatctatg atattttgat caatgtacga gatcattatg ggaatatcga
    59701 ctgttttatt tctgaaaacg gcatgggtgt agaaaatgaa gcacgattta tcaaggaaga
    59761 tggtatgatc cacgatgatt atcggatcga atttgttcaa tctcatctga aatatgtcca
    59821 tcaagccatt caagaaggtg ccaattgttt aggttatcat atgtggacat gcatggataa
    59881 ctggtcgtgg accaatgcct ataagaatcg ttacggtttt atttcagtag atttagcaca
    59941 agatggaaaa agaacgatca agaaatcggg tcattggttc aaagatgtat cagacagaaa
    60001 tggatttgaa gcttaaagaa tagccaagag agaatgtatg aaaattcccg ttcttaccgc
    60061 ttcaggaaaa agaagttcaa ttatttacga tctttttcaa cttttttgtc tttctatttc
    60121 attttttgta tataatagaa tagtcaaaat taaataggag tggaggaagg catgaggaaa
    60181 aaaagaccgt ttcttctctt ttggttattc ggttttttct tactgcttat tttatccgca
    60241 gcattttcag gaaaaatgac agcagatctt gctcagaaag aaacagaaaa aatcgtagca
    60301 agcaaagaat cagtagataa tttcaaaaaa gaattctcaa cttattggtg ggaggaatat
    60361 aaattaactg ccaattacga aaaaggtgaa ttggacatct atttgccaaa aggaaaagaa
    60421 gaaaatcaat ttatcaatat cgatgacgta cttagtgcga tttctctcag acaatatcaa
    60481 ttcaaagaca aacatttggt cgttttgctt ttgactcatg atggcgacaa ggtagcacgt
    60541 ttgaaaaatg gaaaagtggt tacagcttat tctgaaaaag tggacaaaaa agtggtggcc
    60601 gatcgactag cggaatggaa aaagaccaac gaacaagtca agaaaacaac tgcttcttct
    60661 caaaaaaacg agtcgacaga actaagccct tcagattctg gcagtggaca aacgataacg
    60721 ggaaatgaag aaaatcaagc ctcaatcatt acgaatgagt catcagaagg acaatatcaa
    60781 acctatggac aatgaaaaac agaagttgtg acagaagtgg tcagcttcaa gaaataagaa
    60841 gaaatttacg aaaagtgctt ctcaagtttt tgtaaaattt cggcttattt ccgaagaagc
    60901 tacttctgga acaccgtgaa tcagaggttg tgaaatcagc ggtttgacct
//
LOCUS       DACGLI010000009        57647 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.009, whole genome shotgun sequence.
ACCESSION   DACGLI010000009 DACGLI010000000
VERSION     DACGLI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.009"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            132..506
                     /locus_tag="IXT22_000619"
     CDS             132..506
                     /locus_tag="IXT22_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4862008.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="IXT22_000620"
     CDS             complement(620..1249)
                     /locus_tag="IXT22_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4862009.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="IXT22_000621"
     tRNA            complement(1383..1455)
                     /locus_tag="IXT22_000621"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="IXT22_000622"
     tRNA            1669..1742
                     /locus_tag="IXT22_000622"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            1697..1846
                     /locus_tag="IXT22_000623"
     CDS             1697..1846
                     /locus_tag="IXT22_000623"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862010.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2339..3667
                     /locus_tag="IXT22_000624"
     CDS             2339..3667
                     /locus_tag="IXT22_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4862011.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="IXT22_000625"
     CDS             3869..4702
                     /locus_tag="IXT22_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAQ4862012.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="IXT22_000626"
     CDS             4718..5455
                     /locus_tag="IXT22_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAQ4862013.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="IXT22_000627"
     CDS             complement(5610..6578)
                     /locus_tag="IXT22_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAQ4862014.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="IXT22_000628"
     CDS             6810..7643
                     /locus_tag="IXT22_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAQ4862015.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="IXT22_000629"
     CDS             7677..8516
                     /locus_tag="IXT22_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4862016.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="IXT22_000630"
     CDS             8542..9102
                     /locus_tag="IXT22_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4862017.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="IXT22_000631"
     CDS             9301..11022
                     /locus_tag="IXT22_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAQ4862018.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="IXT22_000632"
     CDS             11187..12329
                     /locus_tag="IXT22_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4862019.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="IXT22_000633"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="IXT22_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAQ4862020.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="IXT22_000634"
     CDS             14129..14776
                     /locus_tag="IXT22_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4862021.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            15169..17814
                     /locus_tag="IXT22_000635"
     CDS             15169..17814
                     /locus_tag="IXT22_000635"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAQ4862022.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="IXT22_000636"
     CDS             18124..19437
                     /locus_tag="IXT22_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAQ4862023.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="IXT22_000637"
     CDS             19427..20080
                     /locus_tag="IXT22_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4862024.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20806
                     /gene="radC"
                     /locus_tag="IXT22_000638"
     CDS             20135..20806
                     /gene="radC"
                     /locus_tag="IXT22_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HAQ4862025.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20701..22053)
                     /locus_tag="IXT22_000639"
     CDS             complement(20701..22053)
                     /locus_tag="IXT22_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4862026.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22119..23408)
                     /locus_tag="IXT22_000640"
     CDS             complement(22119..23408)
                     /locus_tag="IXT22_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAQ4862027.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(23495..24199)
                     /locus_tag="IXT22_000641"
     CDS             complement(23495..24199)
                     /locus_tag="IXT22_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HAQ4862028.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            24399..24665
                     /locus_tag="IXT22_000642"
     CDS             24399..24665
                     /locus_tag="IXT22_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4862029.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            complement(24833..25063)
                     /locus_tag="IXT22_000643"
     CDS             complement(24833..25063)
                     /locus_tag="IXT22_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4862030.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            25135..25290
                     /locus_tag="IXT22_000644"
     CDS             25135..25290
                     /locus_tag="IXT22_000644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862031.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            complement(25599..25823)
                     /locus_tag="IXT22_000645"
     CDS             complement(25599..25823)
                     /locus_tag="IXT22_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4862032.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            26090..26425
                     /locus_tag="IXT22_000646"
     CDS             26090..26425
                     /locus_tag="IXT22_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862033.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            26658..27599
                     /locus_tag="IXT22_000647"
     CDS             26658..27599
                     /locus_tag="IXT22_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAQ4862034.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            27601..28491
                     /locus_tag="IXT22_000648"
     CDS             27601..28491
                     /locus_tag="IXT22_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAQ4862035.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28534..29334
                     /locus_tag="IXT22_000649"
     CDS             28534..29334
                     /locus_tag="IXT22_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4862036.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            29349..30200
                     /locus_tag="IXT22_000650"
     CDS             29349..30200
                     /locus_tag="IXT22_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4862037.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            30197..30514
                     /locus_tag="IXT22_000651"
     CDS             30197..30514
                     /locus_tag="IXT22_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862038.1"
                     /translation="MNLTKQEKRICRQIMLQIIGDRDMDELSQQESRMVRKISKLIGA
                     DTMDRSKPLPKLNFESFTFEKYSHLREVGYSVNAIRKALGVGSSVWAKWRKENVNEVN
                     QND"
     gene            30507..30689
                     /locus_tag="IXT22_000652"
     CDS             30507..30689
                     /locus_tag="IXT22_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862039.1"
                     /translation="MIKLIGKETLKVYYVAETKAEVSRWLLKMFNKTRANASVSQKAS
                     VSETGMPEAMWISRRN"
     gene            30691..31161
                     /locus_tag="IXT22_000653"
     CDS             30691..31161
                     /locus_tag="IXT22_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862040.1"
                     /translation="MAMIPKFRAWDREKDRMIYPSTTGVCFEMNDDGISVLDIDVDYP
                     NDYGFPKIASILMQSTTLKDKNGVEIFEGDIALITHKSTNYADTYWHSYVEVFRAKNG
                     AYRIRGEHIYETELYSNRKQLTVAGNVYNSPELLKRDRFMTTTENPELLKEEQR"
     gene            31158..31700
                     /locus_tag="IXT22_000654"
     CDS             31158..31700
                     /locus_tag="IXT22_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAQ4862041.1"
                     /translation="MNKQELIDKYTAEISRLRPYCPNRHLISDQLKYGLYKEILEDLK
                     QLDEPQKPAVPKFVAEWIEYAKKKGDSLAISFKPWNLYGVEYSKTDRWIEDNQGTFAR
                     AWLIGYEVEKEPLYYVKLPVVYFNHWDLETYLMKDDRGNITIADNNDFDDMKFTESEI
                     KAIDERYWPFAVPVEEVAEG"
     gene            31697..32080
                     /locus_tag="IXT22_000655"
     CDS             31697..32080
                     /locus_tag="IXT22_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862042.1"
                     /translation="MSNLKVGDIVFYKGDEGIIREVMTDGKENFYRVDVSRKSILYLY
                     EDELDLGTQKLNDNQKMVFDYLKSNVEQGGKSVMYSIFLLGDWDSRIGAARNVDIAYC
                     GLNGKQEAEVLSAFAQWGLEQEEAE"
     gene            32077..32307
                     /locus_tag="IXT22_000656"
     CDS             32077..32307
                     /locus_tag="IXT22_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862043.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            32314..32517
                     /locus_tag="IXT22_000657"
     CDS             32314..32517
                     /locus_tag="IXT22_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAQ4862044.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            32514..32810
                     /locus_tag="IXT22_000658"
     CDS             32514..32810
                     /locus_tag="IXT22_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862045.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDIELINDK"
     gene            32887..33300
                     /locus_tag="IXT22_000659"
     CDS             32887..33300
                     /locus_tag="IXT22_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4862046.1"
                     /translation="MQLLREVAFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            33313..33699
                     /locus_tag="IXT22_000660"
     CDS             33313..33699
                     /locus_tag="IXT22_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862047.1"
                     /translation="MWKDYVSLKELKKDLIFKKIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHSSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKEKLCVVTDA"
     gene            34191..34263
                     /locus_tag="IXT22_000661"
     tRNA            34191..34263
                     /locus_tag="IXT22_000661"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34224..34226,aa:Lys,seq:ttt)
     gene            34649..34909
                     /locus_tag="IXT22_000662"
     CDS             34649..34909
                     /locus_tag="IXT22_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862048.1"
                     /translation="MNHEKFIEKCKAIVRERIENEIADLSGAVPEFSVFIVWSCKTLQ
                     NSKALVSASLKGAPYFEITLNGDKGEIYVDTYLKKSNECIKV"
     gene            35514..36347
                     /locus_tag="IXT22_000663"
     CDS             35514..36347
                     /locus_tag="IXT22_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAQ4862049.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFETLSDEEKDIYSSLNDNPSFVLSEEIRLLKIRQFRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKNPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            36340..37755
                     /locus_tag="IXT22_000664"
     CDS             36340..37755
                     /locus_tag="IXT22_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HAQ4862050.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            37767..39296
                     /locus_tag="IXT22_000665"
     CDS             37767..39296
                     /locus_tag="IXT22_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4862051.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            39388..40266
                     /locus_tag="IXT22_000666"
     CDS             39388..40266
                     /locus_tag="IXT22_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAQ4862052.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            40268..40585
                     /locus_tag="IXT22_000667"
     CDS             40268..40585
                     /locus_tag="IXT22_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862053.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            40634..41335
                     /locus_tag="IXT22_000668"
     CDS             40634..41335
                     /locus_tag="IXT22_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAQ4862054.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            41350..42240
                     /locus_tag="IXT22_000669"
     CDS             41350..42240
                     /locus_tag="IXT22_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAQ4862055.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLFGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            42263..42478
                     /locus_tag="IXT22_000670"
     CDS             42263..42478
                     /locus_tag="IXT22_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862056.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            42490..42831
                     /locus_tag="IXT22_000671"
     CDS             42490..42831
                     /locus_tag="IXT22_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862057.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            42831..43202
                     /locus_tag="IXT22_000672"
     CDS             42831..43202
                     /locus_tag="IXT22_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862058.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            43195..43590
                     /locus_tag="IXT22_000673"
     CDS             43195..43590
                     /locus_tag="IXT22_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAQ4862059.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            43592..43969
                     /locus_tag="IXT22_000674"
     CDS             43592..43969
                     /locus_tag="IXT22_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862060.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            43970..44578
                     /locus_tag="IXT22_000675"
     CDS             43970..44578
                     /locus_tag="IXT22_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4862061.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            44578..44919
                     /locus_tag="IXT22_000676"
     CDS             44578..44919
                     /locus_tag="IXT22_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862062.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            45161..47950
                     /locus_tag="IXT22_000677"
     CDS             45161..47950
                     /locus_tag="IXT22_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAQ4862063.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            47940..48680
                     /locus_tag="IXT22_000678"
     CDS             47940..48680
                     /locus_tag="IXT22_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4862064.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            48677..51439
                     /locus_tag="IXT22_000679"
     CDS             48677..51439
                     /locus_tag="IXT22_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4862065.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            51452..52360
                     /locus_tag="IXT22_000680"
     CDS             51452..52360
                     /locus_tag="IXT22_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAQ4862066.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            52360..52980
                     /locus_tag="IXT22_000681"
     CDS             52360..52980
                     /locus_tag="IXT22_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862067.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            52984..53433
                     /locus_tag="IXT22_000682"
     CDS             52984..53433
                     /locus_tag="IXT22_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862068.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            53433..53927
                     /locus_tag="IXT22_000683"
     CDS             53433..53927
                     /locus_tag="IXT22_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862069.1"
                     /translation="MADIVQLKEDGVAKYLKTHVKAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            53941..54288
                     /locus_tag="IXT22_000684"
     CDS             53941..54288
                     /locus_tag="IXT22_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862070.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKSGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            54281..54421
                     /locus_tag="IXT22_000685"
     CDS             54281..54421
                     /locus_tag="IXT22_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4862071.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            54521..54910
                     /locus_tag="IXT22_000686"
     CDS             54521..54910
                     /locus_tag="IXT22_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4862072.1"
                     /translation="MTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTGLAKAWKLKEI
                     SSEIGFEGLLKKVLIFVVIAVAVDVQKIVGNSIPLREIVIMFYVANEGISFLENISVF
                     LPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            54907..55917
                     /locus_tag="IXT22_000687"
     CDS             54907..55917
                     /locus_tag="IXT22_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4862073.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYSINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTL
                     SDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIP
                     KR"
     gene            56032..57240
                     /locus_tag="IXT22_000688"
     CDS             56032..57240
                     /locus_tag="IXT22_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862074.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
BASE COUNT        20073 a         8864 c        11790 g        16920 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttccggaata tataagttag tacacataaa
    20701 ttatataagg aaatttactg ttatattgcc atctggaaat actattatgt tatcgataat
    20761 tgaacgccat aatgcatttt tttcttcttc cgaagattct ttataaattt catcgaattc
    20821 ttttgataga ataaattcga cattttttat atctatttta gctggctcta cttcaatttc
    20881 atttaattct ttcattaaag cttctcgatc ttttttgtat tcctctaagt ctataacttc
    20941 attcaagtag gctttcttca atctatctaa tttattctca atatttttct tactattttt
    21001 ctttttaata atctttggtt gtttttttga atagtttatt tgtatttgtt caaatttttg
    21061 tttagtagct tcaaaaatat aacgttctaa atttttttcg taaaaagcgc gcttatttgt
    21121 gcaacgtaat ttattatttc ttcgttttac acatctataa caagtccttt cgtatataga
    21181 ttctgtaccg tcttttttct tatatcttgc tttaatagtt tgaccagcta ctgatccctg
    21241 acagtcagaa cattttaata aacctttaaa aatgtaatca cgttttgcat ttgtttttaa
    21301 atttttaggt aaggcttttt gaacagcata aaaaagtttt ttatcaataa taggaggaca
    21361 gtaattttta ttatttctta attcaccaat gtattttttg ttcgtcaaca tatttttaac
    21421 actttgataa tctctaacga ttccatactg agagcctaaa taataaacag tttttcttaa
    21481 actaccacta gaaagaaagt agttgaatat atctatcacg ataggagcat catcatttat
    21541 tactaatttc ttattttcta tagagtagcc taacggagtt ttcccgctta ctacttcacc
    21601 ttgtgcaatt ttatttgcca taacagcttt gatgcgttct gaatcaattt gggcttccaa
    21661 ttcagcaaaa ctcattactt gtgcaatgaa agttctgcca tacgctgtag ttgtatcata
    21721 atattgttga gaaacagcat tccaagaaac attgtgtttt tctaaaattt cttgagtgtt
    21781 taaataatgt cgtagatttc taaaccatct atctaatttt gtaaataaaa ttagatctat
    21841 tttattttct tttacatctt gtaatagttt ttgaaattca tcacgattta ttttttgacc
    21901 agaaatacca ccgtctacat attcattaac tactttcaaa tccttgtgtt gttcgatata
    21961 ttcatagagg gtttcttttt gttctctaag actatctcca tgtttggctt gttgttcagt
    22021 tgatactctc atatataatg ctactcgttt catgttatct cctttcgaat gtatgttctt
    22081 atcgttgtaa aagaaaagcc cgaaggctaa tctttttact acacatctgt taattctaat
    22141 gatcttctgt attgttcagc ttgagctagt ttagtaaaag atacagttcc gttataattt
    22201 tctaaaacaa ctttttcaat ttcatcaaga gatactttaa agaattcttt tcgttgatta
    22261 actttattga cttcgttttt tctaaaatgc gaatgtagtt gattttctaa tgttggtgca
    22321 tcttctgaaa atatcattgc atgaacatca aattcaaaag gtacagaagc gctactaagt
    22381 tccttaattc tatccatagg ttctaaccgt ctagtcattc ctattttata gacatcttca
    22441 ccgaaagatc cgatattact gatgacataa acatagccag ctctagtatt aagttctctt
    22501 tgcaatacat cttctttgac agtttctagt tctcttaatt tctcttccag ttctttaatt
    22561 ttatcagcat agagttcttt ttcaacatca gcactagctt tttgcatgta tgccattaac
    22621 ttagttatct ctgagttaaa ctgtcgttct tctttatcaa tgcgtttctt ttcacgttct
    22681 atttcacgtc ttaccttttc ttcttcaatc atttgttctt ttattgcttt ttgctgttct
    22741 ttttcatcgt taactttaac tatgtatgaa tagttgagtt ctaattcttg aagttttaat
    22801 tcaagtaatt cttttttgaa ttctgcttca tcgtttttaa aaagcttgtt tattttatca
    22861 aaagttctta taattttttc tctagttgaa tctacgttag aaatagtaag tttattgaga
    22921 agtccagtta tttctgattc taatggtata agcattttct ttttaatatt attagcttct
    22981 ctattattca aataagaagg aatattaatt gcaccgtcta aaataaaatc cttttcttta
    23041 atctttaata aagaaagttt gttttttatt tcggatgaag aagtttcatc tatattcgga
    23101 ataattactg atttatagat agtgaccaga gatgtgtcat atttttgatt aatttcatcg
    23161 tctaaccgct ggctttcagc attaagaata tcaattttgt tttctagcgt tgacaagttt
    23221 ttattcaatt tacttatgtt tttctctttt tcagatataa acgtttccct agcatttaat
    23281 tcttgagaat attcctttac cttactctct aaggcagaag ttttatcttt taatttttta
    23341 gcttcagata atttgctact acccataatt attaaaacta ttccaactaa aaacaatagt
    23401 actcccattc aaaacgcctc gcttctttta taaaataatt gtcaaaatca tataaaccct
    23461 taccgaagtt gacggctccg gcatgggaat ttttttaaaa tacaactttt ccgataattc
    23521 taatctgttc tggcgataca attctatctt cgtataagtc gtttatagaa cgtaaaatga
    23581 ttgtttgatt ttcgtaatct ttatatatct ctttacatgt aactccgtca ccacctaatt
    23641 ccacaatagc aatttcccca tcttctacgt ccggttgttc tttaacgaat acgaattgtc
    23701 cattcctgat aacaggttcc attgaatcgc ctataatagg tactgcgaag tcagcagcac
    23761 ttggaactct ctcaaattct tcctcttcga caaccgtatc accgtaagta agttctgttg
    23821 gattggcagc cgaagccgaa ttgtgaacag ttgggatttt ttctttttta ggaaaatcta
    23881 ggacattttc ttgtttttgt tcttctaatc gattacttgc aaattcatag gtagcaactt
    23941 tattttcgtc gttaagctga ttatatatag gaaggatatt atatatctga ttagatatag
    24001 ataaatcaat attcatcaaa tcatctatat caacattgaa tatcttagct atctcattta
    24061 aggtttttaa ttttggtgta tattttcctt tttcccattc gcttattgag gatgaacttt
    24121 ttcttcctag tttttcggct agttcttgtt gatcaatatt atacttttct ctaagaaact
    24181 ttagattttc agcgaacata gtaacacctc cttgagttaa ttgtaacacc gtttcggaaa
    24241 aaatgtaaca ggtttcttag aaaatatttt agtgttttta aagaagtatt tacgcaaaat
    24301 agaaatcgat ttcaggaaaa ctgaaatatg cacttgactt cggaaaaacc gaagtatata
    24361 atttagtcag aaagttaaag agaggaggcg aataaaatat ggataccgcg aagaaagaaa
    24421 aatatacatt gagacaatta agagctttaa agggttattc aaaagaagaa ctgtcaagga
    24481 aaagcaaagt gacatcaaga acaatattta tttacgaaaa cgatgtagat aaaatgagga
    24541 acggaaagta cgccactcta gaaaaaattg ctaaggcatt gggtgttaga gtttccgata
    24601 tttttttaga ccctgattcg gaaaaaccga aatcaataac aggtgaaaca aaacaagtca
    24661 gctaggaggt gtgaatagtg gaagagaaga atataaaagt accgactctt gaagaatata
    24721 caaaaattgt tgtcgaaaca gacgagcaga acccgaaaac aatcgcagtt attacggcga
    24781 atgatattga atcatgcgaa ggttttcgag ttcgaatgac ccctagatat gattaatgtt
    24841 ctttatcacg tggaggtata ggatcgtttc caaaactatc ttttgattgt atttgtccat
    24901 tctttttttg gacaataaac tctgattgct gttttttaga aatcttttta ccatactcaa
    24961 cagcatctga tttattatca aatagttttg tatcttcgga attaccttca ccacgtacag
    25021 cccatttgcc atttctagga gatacccatt gatttttacc cataacaatt cacctcgctt
    25081 tcaagttaat tctattaaga ggtgaaaaga aaacaaactg atggaggtga gattgtgagt
    25141 aacaagccaa aaatcacttt gaatggcaca cctaatcttc aaagattagc agatgaaatg
    25201 gctagaatac gttctagaca ttggggagtt actgtggtgg caaccataat tgaacaaaaa
    25261 gaaaagccca cacagccggc aagcaagtag tgggcaccat agaacaataa tattatatca
    25321 cacactcgcc acttccgaaa agaggagttg ctgctctcct ttcaagtttg ccaaagtcca
    25381 cgtttcttca ttttggcaac tcctcttctt ggaggtggtg acggcgagag acgaaggagg
    25441 gatgacatga aggaagaatc aaaaataggg attttgaatg agaacaatta cacaagatta
    25501 attattgaaa cagaagaagg ggaaaaagta gcagaagtta cattgaccga tgcaactcct
    25561 gctgacggtt atcgtattcg attaactcct aaatatgatt aaccttttgg tgggtgtgga
    25621 tcgtttccgt gactatcacg gctttgaatt tttccatctc tgccatgaat aaatagctca
    25681 gatccttgat ttttagaaat ctctctagcg atttttactg cttctgattt tgtattagta
    25741 tgtgcagtcg ctttagaatt tccagcacct ttgacattcc aaccaccatt ggaattaggt
    25801 acaacatgtt gattttttcc catagttttc acctccattt ctatagaaat attttatcaa
    25861 atagaaatgg agaaattcaa taaacgaaag gagggatcaa atgacattac aagagcatca
    25921 acacttgatg cgaaaactaa atcaggaata ccacgaggaa atgaaaccta gattgctagg
    25981 ggaacaatgg cgtgaacgcc agaagaagtg gttagaaata aaaaagtgac tcagccgtcc
    26041 aaagcaatga gtcacaaacc aaaaattata cctaaggaga ttttatcaca tgaataagaa
    26101 aattgaaaat cttatcgaag aattgaaacg tgaatgccaa aagcaaggtg tttctattat
    26161 ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt tatggtgaga caacagaaat
    26221 tttactttgt cttgctatgc aagaagaaca tttagatgaa aatctcccat tgtcagcaca
    26281 tattatgcgt agaattgctg tggatgctta cgaacaagcg aaaaatgaag aagaaaatca
    26341 accttcaaat catacttttg ttattaataa caaggaagat ttagctgatg tgatgactcg
    26401 tattctcaag ggggaatttc aatgatgaat gaaaaaacaa ttgatctact cattatttta
    26461 tttttcacgt tagtgattgt agcgaaaagt tatgtaatct ttggcttgtt attcgcaatt
    26521 accatgcttg tgctttgcgt gttagcaagc agaaaagagg ttaaacatga acgagttagc
    26581 aaatcttgac aactatttaa ctgatcctga ttatgctaaa ccaccatatg aagcgccaat
    26641 tgatgaggag gatgaagatg agtaaatcta ccttagaaat gagccatcaa gaatggctcg
    26701 aagaccgcaa aagaggtatt ggtggctcag atgttgcaac cgtacttgga ttaaacaaat
    26761 acaaatctcc ttatcaattg tggcttgaga aaacgggtca aattgaattg aaagatttag
    26821 aaagcgaacc agcttattgg ggtaatgttt tagaagaagt ggttgctaaa gagtttcagg
    26881 aacgtacagg caaaaaagta cgcagaagaa accaagtatt tgaacatcca ttacatccat
    26941 ttttaagagc aaatattgat cgggaagtag tgggagaaaa tgccattctg gaatgtaaaa
    27001 cagccaatca atttctcgga aaagagtggg aaggtgaaga ggtaccgctt agctatctct
    27061 gtcaagttca gcattacatg aacgttttaa acaaagacta ttgttatatc gctgttttga
    27121 tcggtggaca aaaattcatt tggaagcgga ttgaacgaga tcaagagctg atcgatacaa
    27181 tcactgaaca attagtagag ttttgggaaa cgaacgttct tggaggtatc gagcctgtaa
    27241 ttgacggaag tggagcgact gctgacttct taaaagaaaa atatgcagat gtagaagaaa
    27301 atcaaacagc tctaccatca cgttttgatg aacttatcga gcaaaaaaga gaactcaagc
    27361 ggacgaaaaa agaaattgaa tcatctattc gtcaagtaga caacgagatc atcagtgagc
    27421 taggtaaacg tgaagccagt atcggtatca cacaaagaaa cattatcagc tggaaacttg
    27481 ttcgtacaag acggatgaac acgaagaaac tagcagagaa atatccagat gtcgcaaatg
    27541 atgaagagat ttataacgtt actgaatcaa gaaggctaac cgaaaaggag atcaaataat
    27601 atggcaacaa atgaatcgtt aaaaaatcaa ttggcagaaa agccacagaa acaagttgca
    27661 ccaggacagt tagggcttaa agctctaatg aatacaccaa caatgagaaa gaaatttgaa
    27721 gaagtacttc atgacaatgc taatgctttt atgtcgaatg ttatgactct tgtatctaat
    27781 gacagttatc ttgcagatag tgaaccgatg tctatcatga gtggtgcgtt aactgctgca
    27841 acattaaatc ttgggctaga taagaattta ggttatgcat atttagttcc attcaatagt
    27901 aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat tcatgcttgg ctataaagga
    27961 tatatccaat tagcccaacg atcaggtaaa tacaaagcat taaatgtgat cgaagtttac
    28021 gaaggagaac taaaaagctg gaaccgactg acagaagagt ttgagtttga tccaaatggt
    28081 agaacgtctg atgaagtcat tggatatgtt ggctatttcg agttactgaa tggattcaaa
    28141 aaaactgtct attggaccaa acaagaaatc gaagctcatc ggattgctaa caataaagat
    28201 cgcgataaga caaagttaag tggtgtgtgg gcatctgatt acaatgcaat ggcacgaaaa
    28261 actgttttga gaaatcttct ttctaaatgg ggaatcttgt ccatcgaaat gcaagaagcc
    28321 accacatcgg atgagagagt ccaaagggtt caagaagacg gcagcattat tgctgaaaca
    28381 gaagttgaag aagatattcc tgaaagaaaa gaagcagagg ttatatctga agaaaatgaa
    28441 gatgtacaaa ctggattatt tgatgcatct aatccgccgt taaacaaata atgagggagc
    28501 tttctccctt gcttttctag aggagaaata cgaatgaaca caggatatgt caaattacat
    28561 cgaaaagtga tgaattcatt cgtttggacc aatccttata tgtataaatt atggagcttg
    28621 tgtttgatga aagcgagtca tgagaatcgc aagatacttt ttaatggaaa agagatacaa
    28681 gtgaacagcg gagaattcgt cacagggcgc gatgctatca catctgagat gaacgaaggc
    28741 gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga gatggctaaa acaatttgaa
    28801 aaaaacggaa tgttgaacat caaatcaact acgaaataca gcgttatatc aataaaaaac
    28861 tggtctttgt accaaagcag tgaacaacaa atgaacatca aacgcacaac aagtgaacaa
    28921 caagtgcaca caaacaagaa tgaaaagaat tataagaatg aaaagaataa taaaacatca
    28981 tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact cagtttacta cattctcgcg
    29041 gaggagttat tcaaacagat ttgtcagaat caggaaatca aaaagccgaa tctgcaaagt
    29101 tgggcagata acattcggaa aatgatcgag atcgacaagc ggaccgaaaa ccaggtacgg
    29161 ggaatgattg aatggagtca gcacaatgtg ttttgggcat cgaatatttt atctgctaaa
    29221 aaattgcgag aaaaatacga cacaatggca gcgcaagcaa atcgtgatta taaaacaaaa
    29281 caaactaaaa cgcttgaata cgagaaattt agcacagatg agttgcctat ttgagaggag
    29341 gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct gatacagaaa gtgcttgtcc
    29401 aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg atggcgtacg aagaaccctg
    29461 atggctcaga acgttgtaag ccaacctgta tgcaatgtgg gtataaagca ttgcgagttc
    29521 aggaagactt acaaacagaa cgaatttaca acgagagcct gaaagcaaga gcaatcaatt
    29581 ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt tgattgcaca ttgcagaatt
    29641 atcaaattgt cgatcaagaa acaagacaag cggttgaagt aaccaaacgc tttgttaatt
    29701 cagtcttgtt aggaaatcca agtcaccttg ttttaactgg aaaacaagga acaggtaaaa
    29761 gtcacctagc gatggcagcg gcttgggaag tcttgaagcg atcaaactac gataaaaaaa
    29821 tcttatttat cgggttacag gaaatgctgg atcaaatcaa attttcgtac aacaatcctg
    29881 aactcagaaa aacgattgag ggatcgttga ttgcagatat caaaacagcg gatttagtca
    29941 tcattgatga tatcggttca gaactaggaa aagatgcatc agatagtcga gcgtttggca
    30001 taaacacgct aaattcgttc ttggatgcac gacagaacct agcaacgatt atcacaacga
    30061 acttgcttgg tgaagaactg aaaaaagctt acggtacgag aacaatatca agaatgtttg
    30121 tcaactctga tggatttacg atggtatttt ctcaaacagc agacaagcgc ataaaaccag
    30181 tcaaaggagc gatcgcatga atttgactaa acaagaaaaa agaatctgtc gtcagataat
    30241 gttgcaaatt ataggtgatc gtgacatgga cgaattatct caacaagaga gtcgaatggt
    30301 tcggaagata agtaagctaa tcggtgcaga tacgatggat cgatccaagc cattacccaa
    30361 actgaatttt gaatcattta cgtttgagaa atatagccat ctgagagagg taggctatag
    30421 tgtaaatgct attcgaaaag cacttggggt aggaagtagt gtatgggcaa aatggcggaa
    30481 agaaaatgta aatgaggtaa atcaaaatga ttaagctaat aggcaaagag acgctcaagg
    30541 tttactatgt agcggaaaca aaggcagaag tcagccgttg gctattgaaa atgtttaata
    30601 agactagagc caatgcttca gtaagtcaga aagcaagtgt atcagaaaca ggcatgcctg
    30661 aagcaatgtg gatttcaagg aggaactgag atggcaatga taccgaagtt tagagcgtgg
    30721 gatagagaaa aagacagaat gatttatcct agcacgacag gagtttgttt tgaaatgaat
    30781 gatgatggta taagtgtgct tgatattgat gtagattatc ccaatgacta tggttttccc
    30841 aaaatagctt caatcctcat gcaatctacc actctgaagg ataagaatgg tgtggagata
    30901 tttgaggggg atatagcgct tatcactcat aaatcaacga actacgccga tacttattgg
    30961 cacagttacg tagaagtttt tagagcaaaa aacggagcct acagaattcg cggtgaacac
    31021 atctacgaaa cagaattata tagtaataga aaacaattga cggtagcggg gaatgtttat
    31081 aattcaccag aacttttgaa gagagatcga tttatgacta ctaccgaaaa tccagagtta
    31141 ttgaaggagg aacagcgatg aataaacagg aattgattga taaatatact gcagaaatat
    31201 ctagattaag accttattgc cctaatagac atttaattag cgatcaactt aaatatggtc
    31261 tttataaaga aatcctagaa gatttaaaac aactagacga accgcagaaa ccagcggtgc
    31321 ctaagtttgt ggcggaatgg atagaatacg ctaaaaagaa aggcgatagt ctagctattt
    31381 cattcaagcc gtggaacctc tacggtgttg agtatagcaa gactgataga tggattgaag
    31441 ataatcaagg aacgtttgct cgtgcttggc taattggcta cgaggtcgag aaagagccgt
    31501 tgtattatgt gaagttgcca gttgtgtatt ttaatcattg ggatttagag acgtatctaa
    31561 tgaaagatga tagaggaaat ataacaattg cagacaacaa cgattttgat gatatgaaat
    31621 ttacggaatc agaaataaaa gcaattgatg aaagatactg gccatttgct gtgccagtgg
    31681 aagaggtggc ggaaggatga gcaatcttaa agttggagat attgtttttt acaaaggtga
    31741 cgaaggcatc atccgagaag ttatgacgga tggaaaagaa aatttttata gggtagatgt
    31801 cagcagaaaa tctatactct acctgtatga agacgaatta gatttaggta ctcaaaaact
    31861 caacgacaac cagaaaatgg tgtttgatta tcttaaatca aacgttgaac aaggtggcaa
    31921 atcagttatg tattcgatat tccttctagg tgattgggac tctcgaattg gagcagcaag
    31981 aaacgttgat atagcttact gtggattaaa tggtaagcag gaagcagaag tcctatcagc
    32041 attcgctcaa tggggattag aacaggagga agcggaatga aatacgaaat accactaagt
    32101 gaagcagacg tccagtcaat tattaacggt cgggaggtta ataaaaaact tcctgatggt
    32161 actgaattag tcatcagaca aagttatttg aaagatatgg cagctccagt attaattgat
    32221 cgttttaacg tgactgattc tgtggtagag aaccatttaa aagaatttcg atcaagtata
    32281 gacgacactt tcagattagg gagttgattg acaatgaaca acagacatcg cagaataaca
    32341 aaactaagaa aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt
    32401 tcagcagaag aaacatataa agtggcaagt cagtgtgttg ctgatgcgag taatgctatt
    32461 cgtaagtttg ggatttcgat attaaatgat gatcgtaaat gggaggaaat gagatgaaac
    32521 taaaagacgg attttacgct agtagtcacg gcatcggcgg tttaatgcta gatatgccga
    32581 caaagaatcc taaaacacgt aagaaaccaa aagtcaaagt cggtgacatg gttcgctgcg
    32641 aagcagaagg gttcatctat ccatttcgtg gatatgtaga acacgtctat aatcactcag
    32701 caatcattcg tattgaaaac acgatggaat gtgataaatg gacagctaaa agcaaagaga
    32761 atttagcagt ggtgagattg gtggatattg aactaatcaa tgacaaataa aaaagccgga
    32821 tcgctccgac tgattcaata aattccacaa gtttattata tcacataaaa ggggcggttt
    32881 gacttgatgc aattgttacg agaggtagct ttcaaacaga caagatgtaa tgcgagagat
    32941 gtgctgaaga actttcggcg tttggagcgg atggcaggtc gctctttgat agatattaag
    33001 tcgccgatta ttacggacat gccgaaggca ccgaagcacg gcaataaggc agaagacgcg
    33061 atcattcaga tgatggatat agaagcagag agagacgcga ttttagcggc tttgatggcg
    33121 cttagtctga ttagtcgtca gatactctac tacagctttt gtgtgccaga tagcttctca
    33181 aactacagga ttagccgtga agtgggttat tcagaaagaa gcatacaacg gatgaagtcg
    33241 gaagctctga tagagtttgc agaagcatat aaacatggga aaataattgc ttataaatag
    33301 gaggactata taatgtggaa agattatgta tcattgaaag agttgaaaaa agatcttatt
    33361 ttcaaaaaaa tcgtagaatg gtcagagagt gaattaattt tagaagatgg aaccaaaatg
    33421 gaagttgtat gtagcgaatc agattgctgc gcatgggccg aaggtgaatt caaaaatgta
    33481 aagcttgatg cagtgattac agatataaag atttttgata aaggtaaccg tctctataat
    33541 ggcgatggac atagttctta tgccgaagtc gttgtttatc ataatcgaaa tgagattgct
    33601 aaagcggaat gtacagcaaa cgatgggaat ggaggctact attacagtgt ctgtgcttta
    33661 aaagtcaaag aaaaactttg tgtagtgact gatgcataaa aaatggcggt tttttggcgg
    33721 aatgatggcg gtttttagct atttaccagt gatattatgg tagtgtcgaa agattagtga
    33781 taggtctgag acaaaataaa atgtaaggga ggaaatctcc ctcatcgttt aattaagctt
    33841 cgatagacag cagcggaaat attaagaata aggatgtgaa ttttaactcc ttctaaattg
    33901 ttcttattat ctatcatccg ttgctgtcta ttgttattat gtcactgtgg cggaaagggt
    33961 agacgcttaa aaataaggtc aatacgtcga gggatagcct taacgtttta tgatttgacc
    34021 atgcaaggtt cgattccttg ccagcgactt agacgaaagg tagcttaaat attaaccaca
    34081 tcaacatcgt cagcgagttg ataaaggtaa ctagcagact ctaggattta agccagtctt
    34141 accgattagt ctgttatagt agcaagcttg ctagaggtag ctcctctggt tgacgtgcag
    34201 ctcagttggt agagcgcctg acttttaatc aggaggtcgc cggttcgaat ccggtcacgt
    34261 taataaagaa cctacggaaa caatcaatct tatcggatgc cgattggttg gctgaattaa
    34321 gcagtgtgtc tgtgaatcag ttaataggca taaaatacta gcacagacgt gtgccactct
    34381 caggtgtagg ttaggagaga aacattagca accgagggtt ggaaatgggc gctcaaagta
    34441 cacgagcaag gcgaggtcga tagtaatcga tggaatcggt gtaggttgct attacataat
    34501 tgattgggtt agattgagtt ttgggattcg gtacaaatga atcgtcaaat gactcaagca
    34561 caggatcgga aacgtccctg cctgtgcatt acatattaga tcactcgttg agtggtcttt
    34621 ttattttaga aaagagagga ttttgaaaat gaatcatgag aagtttatcg aaaaatgcaa
    34681 ggctattgta cgtgaaagaa ttgagaatga gattgctgac ctaagtggag cagtacctga
    34741 gtttagtgtt ttcatagtct ggtcatgcaa aacactacag aatagcaaag cattagtcag
    34801 cgctagctta aaaggagcac cgtattttga aattacgttg aacggggaca aaggtgaaat
    34861 ctatgtagat acttatctca aaaaatcaaa tgaatgtatc aaagtctagc aggtgctagg
    34921 ctttttcttt acataaagga ggaatgatct catgaaacaa tataccgcta aagatttcga
    34981 ggaaatgaag cgattaaaga aggactatga agaagttgat atggagctaa ctgttggagt
    35041 cattcaacga agactgcggg tcggattaga gacagcaaag gctatttaca atgatctaaa
    35101 tgctattgaa gagaagaatg gctaatgagg aactactggt atatatcgct aactaatgaa
    35161 tatcctcgaa ccattgatga ttgttcagtg cgtgttgtgc gttctgtaca aatcaaaggg
    35221 aagtactcta ttgtcgaaat ggggagagaa gcagaaccat gtgagattga tgcgtgcaag
    35281 ctcgtttatt gcggtcatgg tttctatgat gaaccaaaca ttcaaaataa tattaacaag
    35341 aatttgaggg attagaatgc aagaaatggc ttaaaaatct ccaatcagga caaatcaagt
    35401 tagacaaagt ttccgattta aagatattaa ttgaagcaga tctaatgttg aaagatattg
    35461 aaaattagaa aacaaaactc aacctaagaa gattgcgagg tggtgtgtat tgaatggcaa
    35521 gacaacgtga tccaagacgt gatgaagcca aaagaatttg gttagaatcc aacggagaaa
    35581 agcagttaaa ggaaattgca tctgaattaa atgtttcaga ttctcaggtt agaaaatgga
    35641 aatcgcaaga caaatggagc gctgaattga aaagtaacgt taccaatggc aaaagtaacg
    35701 ttactaatca aggtggcgct cctattggta atcaaaatgc taaaggtaac aaaggaaata
    35761 gccgagcttc tccgccagtg ggtaataaaa acgctttgaa aacaggcgag tatgaaacca
    35821 tattttttga gacactaagt gatgaagaga aggacatcta ttctagtctg aatgataatc
    35881 cttcttttgt tttgtctgaa gaaatacgtc tacttaagat aagacaattt cgtatgatga
    35941 agagaatcca acaagctgaa gctggactaa atgatgaaga agtcgaacga ttgcagcagc
    36001 taagaaagat taaaaatccg attgaaaaaa atggtaaaaa gctagaaatc aagcgtgagg
    36061 ttatgcaaga tgtgcagatt agcagaaaaa aacatcgcaa aattgatgat attctttcaa
    36121 ttgaagattc attgactcgg attagcaacc agttagctaa agccatcaag caaatgaatg
    36181 aactttatat gaatgaatac agaactgatt taattaaagc tcagactgat aagatccaag
    36241 ctgagacaaa tgaaattggc ggaaataatt caggtgaaga aatagaagaa tggaaacagg
    36301 cagttttaaa tgccgcaaac aaacgggcgg tgaaagaaaa tgaataatga atttattcct
    36361 tttgctgata ttggttctgc cattgattat tactatgata aaccagtagc tttttgccaa
    36421 gatattttgc atttgaatcc tgatgaatgg caagaaaatg ttttaaatga tttagctgaa
    36481 ttttcaaagg tttctgttcg ttctggtcaa ggagttggaa aaacagcatt agaagcagga
    36541 gcaatacttt ggttcttaac gtgtcgaccc tacgctaaag taatagcaac agctccgaca
    36601 atgaagcaac tttacgatgt actttgggca gaggtagcta aatggttaaa tgatagcttg
    36661 atcaaaaact tactgaagtg gacaaagacc aaaatttata tggttggtga ttcagagcgt
    36721 tggtttgcta cggctagaac agcgactaaa ccagaaaata tgcaaggttt tcacgaggac
    36781 catatgttga ttgtggtaga tgaagcttct ggtgtgtctg atccaattat ggaagctatt
    36841 cttggtacgc tatcaggttt tgataataag ctgttgatgt gtggaaaccc caataatatt
    36901 gaaggtgttt tttacgattc ccacaattca gaccgtgata aatacagagt tcataaagta
    36961 tcaagctatg atagtaaacg tacaaacaaa gacaatatag aaatgattct taaaaaatat
    37021 ggaaaagaaa gtgatgttgc tcgtgtccgt atttttggag aatttcccaa aggtgcgttg
    37081 gattcattta tcagtcttga aacggttgaa ttggctacag aaaaacaaat tagtgattct
    37141 ttagtcaata aaacaacggt tgctcatatt ggtgttgacg tagctcgata tggtgatgat
    37201 tctacgattc tctttcctag aattgctacc agggcattgg agtatgagaa gtattcaaaa
    37261 cgtagcacca tggaaacaac aggatatgtc atcaacatgg ccaagaatct aatgagtcaa
    37321 tatccgagta ttgataaagt gatgattaaa gtcgatgaca ctggtgtcgg aggtggtgta
    37381 accgaccgcc tagaagaact tatagaagac aaacattatc cttttgaggt gtttggagtg
    37441 aataacggtt caacatcaga agacgatttt tacgataatt taggtactca actatgggga
    37501 aacatcaagg aaatgttaga agaaaatatg acagcaaatc ttaacggaga acagcctgtt
    37561 attgaattgc cttctgatag ttcgttaatc aaagaattaa gtactcgcaa attcaaaatg
    37621 acaagtagaa gtcgtatacg tttagaaagt aaagatgata tgaaaaagcg aaatattggt
    37681 agtcccgata ttgctgacgc actggcttta gcgttttatg agccaccaag tcactatcaa
    37741 tttattcaat tttaggaggt gagcttttga ttagtacagt attatcttta gagagatata
    37801 agaagctacg tgttaaatat gcaacacaaa ttgaagatgg aatgtttgat ccgaatggtt
    37861 ttatagaaga tatgaaacca ttttttgctg atcgcgaaag aaaatatcta gcttatacta
    37921 gcgaaaagaa tgaaatagat aatagaccaa agcctaacac tgatattgta aaagttaata
    37981 ataaacttca tgctggtatg tattcaattg tcgtagacca agcagtcaat cattttactg
    38041 gtatacctat caaatgggat tacgatgtat cggaacaaaa aagaacactc attcaaagat
    38101 taaaagataa attcttaaaa aatgatatag aacttccgac agttccagaa gcttttaaca
    38161 aattaacaag caatcttgat tccatgagat tcgcaatgct tgattctgaa actgcaactt
    38221 ttcaaggagc ttgtggagta gctttccgat tgttagagcc tgtggaagaa gatgatggtt
    38281 ggaagttaag agcaagtaat attgaacctt ggagagcaga aagatatgga aatgccggaa
    38341 tctatatcaa agaaaagtat gactcttacc agaaaaaatt ttttcaagaa atgaaagtta
    38401 tgacgagaaa taaaattctg acatatgctt gctatggtga tttgaatttt gttacaagcg
    38461 gaacgttcaa aaaaattgat gagaccgata accctttggg gacgattacc ttggcagaat
    38521 ttaaaaataa tacgaatcgt tattgtgatt ttgaagtagc tgaggaaatt ggagatgcaa
    38581 ttgatcgtgc tttgtctgat caacaaaacg aaatcgaaca atttaagctt gcgtacatgc
    38641 ttgttactgg cacaacaatg agcaaaggca ctgctaaaga aatgatgaat cagctaggga
    38701 ttatcaactt aaaagaccct actgcaaaag ctgaatatgt cacaaaaaat ttagcaaaag
    38761 atttcaatga atatcatatg gatctattga aaaaacagtt ttacaccatt tgtaaagcaa
    38821 tcgattttaa cgatgaggtg tttaaatcaa acagttctgg agaagctcgc aagtggcaaa
    38881 tcattagcct agaagcgaaa acaaatacta aagagcaata ttttagagaa ggattgaaag
    38941 aatgcgcaga aacaattgct gcttttctta agtttcatga caaagtagaa attgagcctg
    39001 aaaaaattat ttttactttc tctagatctt tgccaactga tttaagttat ttagctgaag
    39061 ctttacctaa acttgcacca tacgtatcca aacgaactat tcagagccaa attccatttg
    39121 taacagatgt tgattatgaa aatgaaatga tggaattgga aagtggaagt gcttatccag
    39181 atagtgaata caattttggc ggaggtggca atagtgacga tagaaacgaa gtattggacc
    39241 aaacgtcgag aactggagga tcaagcaagg ctcaaacaag aaaatcagac acttaaaaaa
    39301 ttaactagtg tatttcctga agcactgaaa gagatacaag caaaactatt atcacaagct
    39361 gacttacaca atatcactta tccagaaatg atggagtttt atagtacaag taatcagaaa
    39421 aaatatcgtg aatatgtgga aaaaaattat aagtcattaa aaatgtatga tgcaaaatac
    39481 aaagagttta tcgatgaatt ttttccacca tttgactatg caaaagtcaa tcgcttatta
    39541 caaatacgat cagatgtatt taaaattctt gcagaatatg cgatggatgc agatgtgaat
    39601 caatattttt ctgatcgctt agaggaaatt cttcaaagaa catattcttc taatgctaat
    39661 gtttttgttc aacttttaaa cgttgatata ccaaattatt taccagaaaa tgaaattaaa
    39721 cattatttga actatccatg gtcaggaaag acattttcaa gaagactttg gggaaatatt
    39781 tcatcgcttg aacagaaact ctctaatgct attgtaaaaa gtgttgctag tggagaaggc
    39841 gttatacacg cattaaacac catgagatta gactcagaaa tttgtgacat gtttaagtta
    39901 gaagaatcaa agtataacaa agcgatagaa aatctcgttc gaacggagta tgcaaaattt
    39961 gcacaagatg gtattgaaaa atcatattta gaaacaggta ttgaggaata caacgtattg
    40021 actgcaaaag atgagagagt ttgccggatt tgtggaggaa aggcaagtaa gaatccctat
    40081 aaactgaaag atgctgtcat aggtgaaaat cgagcacctt tccatagtcg ttgtagatgt
    40141 acggatgttc ctaatttacc aaaattagga aaggatattg atgaagaata tgaccgttta
    40201 tttggcgatt tattagatga gtttgcacat gattcttttg gaattaattt gaaacggagg
    40261 aagtagaatg aaagattttt ttgaagcagt actaacaatt aatgtaaatg ctgatattgc
    40321 agaagcctac aaaacagcta ttgagtctga gaaccatcct aatggcttga gagaccattg
    40381 gaatggcaat tatgcctacg tggttattgg cgatcaaact gttaattatc aagataatac
    40441 tccagttgat aagaataccg ttaatttaac gattcaatta ttatctcatt cattaccaaa
    40501 tttaaaagaa acagttgatt ggtatgaaaa gatgggatgt attgttgtta gaactgacta
    40561 caaagaagga aagtctagta attaggcttt tttattttgt ccgaaatgac gttaaactag
    40621 cgcaatactg ggcttggttg aatggtgggg cgcaactatt aaaactcaaa gcaatgcggg
    40681 gcgtgaaaac gaatcgtggg gcgaaaggag aatgagcatg aaacacaaat cattaatgcc
    40741 aatgaatttg caatactttg ccgaaggtga cgatcaaaag ttttcttttg atgacttcaa
    40801 atcttttgtg gaatccaatg aagaagctca aaaatttatt cagtcacaat ctcaaagtgt
    40861 tgccgacaaa caattggaag cttggaaaca aaataactta gataaaatta aacaggatac
    40921 catcaaggaa tatgaggaat ctaagaaaaa caagtcacct gagcaaattc aactggaaaa
    40981 actacaagct gaatttgaag cagaaaaagc gttgcgtgtg acaagtgata ataaagcatt
    41041 tgttgcagaa caaattgctg gattagaact agatggagag ttaaaagagt ctatttctca
    41101 atttatgcta aataatcttg ttagttcgga tacagatttc actaagaatg ctgttgaagg
    41161 ttttacaagt gtcttgaatg caattaatga gaaacatgca gatgcattaa aagaactaca
    41221 aatgaagtct gcatttggtg gaactcaaca atcgaataac caggttcagc agaacaatga
    41281 aacattaaca aatccagaag aacaattagg acaaattctt caacaattta actaggagag
    41341 tgaaaaatta tgaaaaaaac atctttaaat aatttagagt atttggatat ttcaccagcg
    41401 attaatgcta tgcaagtacc aaatacacct tttttaagct atttatttgg tgctggaaaa
    41461 acagagccag caaactcgac agaaattaaa tggcgtgaat atgatatcaa caacgatgat
    41521 tcttctgaaa aacttgaggg cggagaatat ccagatgctg aatcaggtcg aacttggttt
    41581 aacaactata ctgaaatttt tagaaaatca acctctgtat ctggtacatt agatgctatt
    41641 aatgtgaatg gagtcggaaa tgaattaact aatcaagtag cactacgtgg tatggaaatg
    41701 aaaattgatt tgaaccgaaa attgattact ggtgtaaaag ctgatgaaaa tggttctaaa
    41761 ggtcgtcgaa tgaatgggat tttgaacttg atcaattcag caaataaggc agaaacagcc
    41821 actgcgggtg cagtaacaag aaaagatatc gatactttat ttaaattgat gtatgaaaaa
    41881 ggttatatgg gagaaaaact atgcttgatt tctccagata tgcaggagtt aatgactgat
    41941 gagttagatg gaaaatcaac aaaaattgtt cagttcgggg aaagagtaac ttttggattg
    42001 caaattggaa atatcgtgtc taattacggt acaggtattg ctctactaga accatcattg
    42061 ccaaaaggaa caattgccgc aatcgatact aattatgtga aactacgtcc attacgtgaa
    42121 tggagagcag aagaacttgc aaaaacaacg gattctagac gtatcggtct tgtaggtgaa
    42181 tactctcttg aatacaatgc ttcaaactct ggggcaattt taaatttaaa gtctgaataa
    42241 aagggagtta gtactccctt ttttgatagg aggaattaca gtggtaaaaa aagatgaaac
    42301 taaaaaagat gaagtcgtga aatatagagt aggtaaaact aaaaattttg ttgggtttgt
    42361 tcatcctaaa actcgtagat ttatcacagc agattcaaat aacgaattta tcatttctat
    42421 agatgataaa gaagcaattg caattttgga agatgcaatt gatgttaatg aaatttagga
    42481 agtgatctga tggatgaatc gctaaaaacg gaaatcattg agtctacaaa agaagatttt
    42541 ccagatttga gtgaagaacg cataactaat ttattagaaa taattttgct agaaattgaa
    42601 tcatacaaca cttgtaaaaa tgatatttca tgggaaaagt taaaaagcgt gattagtgaa
    42661 gtgttgtata aaataataaa aaatgaatca gaaaaaacag tatcttcagt tagacgtggc
    42721 gatacaacga ttagttatgc ttcaacaaca aatgatgtta gtgagttact tctaggctat
    42781 ggtgatttga tacgaagagt tattggttgt ggaggattgg agttttttta atgaatgaag
    42841 cagatatttt agaaactact tatgaagata gttgtattat tgaaagactg acggacattg
    42901 aagattctaa tacaaatatt actattcaag attacaaaaa agtatatgat aatcctattt
    42961 cttgcgctct ttcacaaggt caaatcgatg gactagcagt catagaagat ggagagatgg
    43021 taaatgtttc aactgacaca tataaattat ttgttcatcc taagattaaa ctaaaaaaag
    43081 gagatcgaat aacaataact caaaaggcca gtggcttaat tttttctcta tttgctacta
    43141 agccttttta ctatcctagt cattgtgaag tgaatttgat aggaagtgag aaaaatgggt
    43201 aatctcaaat atgaatcaaa tgcagaaaag atcattgaga attttaaaaa tatgactgta
    43261 attgctcaaa aagaaggaat atccttcgtt aacgattcaa tgaataaagt cgttagttta
    43321 gctaaaccat taactcctgt aaaatcaggt aatttaaggc gaggatatcg tgtagtaaaa
    43381 gctagaaaac tatcaagcgg tcgaattgtt ggagcagtta taaacaatga acattatttt
    43441 aaatatgtag aagaaggtca taggactaaa aatggtggct ttgtcaaagg gaaattcatg
    43501 ttaactcgtg caacgaatct tgcaaatatg tcttatattc ctcgaagatt taaacaaatg
    43561 gcaataaaaa tcgttaagaa aggaaagtaa catgaaagat gaaatcattg ctgcaatcag
    43621 tagcaaatta aaagaaatct atcctgatgg gacaatatat cttgattcag ttatgcagtc
    43681 aactaaagat ttttatttcg ttttatcagt aatggaatct ggaactgaaa atgtaggaat
    43741 tgatattcaa aatgtttctt tcttaattga tattgcattg attgataata aacctaatag
    43801 aaatttaatt aatgaattag tctcacgttg tgggactttt tttaatacga ttacaatcga
    43861 tgagcaaata ttatttccaa aagcctattt acctgatgaa gcagatggtg ttcaacatat
    43921 tcgttttaca ttagaatttc cacaatatat tgaatggagt gaaagataaa tgggagaaaa
    43981 aagaagtaaa accggaatta tttctgtcga aaaacctact tggtttcctt tggaagatga
    44041 gacagggaat tttccggtat atggtactgc gttgccaatg ggaacagcag taagtatcaa
    44101 accaacagct aattatgaaa caacacaaga ttatggggat tcagtggttc aagatcaatt
    44161 tacagctttt ggtggtgcag aagttgaact ggaagcaaat ggatatactc ataaagtttt
    44221 atctacaatt actggaggga aaattgttaa aggtggtgcc ttgcgttctg gagaagatat
    44281 tgcgcaagat ggtgcgtttg catatagacg taaaaaatcg aatgggaaat accgttatac
    44341 ggtcttttat aaaggacagt ttgctctaga ttcagatgaa acatcaacga ttgaaggaag
    44401 taaagtaagt tttactcatc caacttggaa gggttcattt gtagatgtac caggacttgg
    44461 atatatgtat tcagttgatg aagatgatga aggcgtggat aaagcaatga tcggaaattg
    44521 gtttacaaaa gtagcaattc caattgaaga agcagaactt tcaggaggta cagaataatg
    44581 tcaaaatatc aaacaacgat taaattaacg aaaaaagatg aagaaggtaa atatgagcaa
    44641 gtacaattta aatctgctga atttttacca ggaacagttg tagaagatgc tgcaggagtt
    44701 atggaagaaa tgcaaacagc gactgataaa caatcagtta aaaaagcttt aagtcgtgct
    44761 tattcattta ttgcagatac tttatttgag ggacaattta ctggtgaaga ttattgcaaa
    44821 ggaattgatg ctcgtgagat tgcctcattg acaggaaaat tattgaagtc tgttactgca
    44881 ggttttgatg aaacttatac agagacgaaa aaaaagtaag tgaggcgctc aagtcacctt
    44941 catttaagta ttcgattact taccgagaat tagatataaa gacgcaatta ctcgaagcag
    45001 gttggacgtt accagaaatt gaacgtactg acttggatga gttaatgcgt ctttttgctt
    45061 ttagagatgc ggtaaaagag catgaagatg ttgagtacta tgataatttc actcaatttt
    45121 aggaggtgat actttgaata acgatgacct aattctgaag atgatactag atgaatctgg
    45181 ttttactgcc ggtatgaata atgctgtcaa aaagttgaac tcttttgatg aaacaatcga
    45241 aagaaaaagt agaaatagtg gcagttcatt aggtagtatt tggaaaatat ttgctggaag
    45301 ttttctagct agcggagtaa ctagaatcgt aggagctggc tttgatctaa tcaagggttc
    45361 cataagtgga gcggttgatc gagtagatac gatgaataac gctctacgaa atttccaaaa
    45421 tatgggattt agtaattcag aaattatgaa gaatatcgga aagaatgggc ttttatctca
    45481 aggtattcaa ggacttccta ctgctttgaa tgatgcgata agtcatgttc aacttcttgc
    45541 ttcttctaca ggtgatttaa ctcgttcaac tcaaatattt aaagctttaa atgatggaat
    45601 tcttggtttc ggtggttcaa ctgatcaagt taatgaagct gttattcaat tatctcaaag
    45661 tttctcaaac ggaaaagtag acgcacaaac ttggaactca atgatcaacg ctcaacttgg
    45721 acctactctt tctgctattg ctaaaaagat gggaattaca atgggagatc tgaaagaagg
    45781 tttgtctcaa ggtaagattt ctgttgaaga attccaaaat caattaatag aaatggatac
    45841 caaaggtggc ggaggactta aatcattaag tcaaatcgct aaagattcta ctaagggaat
    45901 taaaacctct atacaaaatg caaaaacagc tgttacacgt ggtgttggtg aggtaataga
    45961 aggattaaat aaagcattag tagattcaga tttaggtgga tttaagggaa ttattgataa
    46021 agtgggcagt tcaatggaat cgttcttaaa agtaattgct gcaaatattc ctacagcagt
    46081 atcattttta agtaatttat ttaacgaaat tcaaaaattt ggttctgctt tgaaattcat
    46141 gatgcccttt cttgttcctg cagctaccgc ttttggagcg ttcatgtttc aacttaaagg
    46201 tataccagca ataataaaaa gcttcaataa ttttaagaat gccataattg gcgttggaaa
    46261 ttcattaaag attatggggg caatagctgc tgctaattca tttgttttaa ttattggtgc
    46321 agtcgttggt gcaatagctg ttttcggtta ctttatggca accaatgaag agtttagaaa
    46381 caaggttata tctatttgga atgatgtgaa agattccgta attggtgtat taaaaaatat
    46441 aaaggactgg ggaattgata cttggaattc tgctaaagaa atggcatcaa atgcagttga
    46501 gggtgtcaaa gatgcttggt caggaacaaa ggaatggttt tctaacacct ggaaaggtat
    46561 taaggatggg gccacaggtt tatttgataa aacagtagag acttcaagaa atgcagtcga
    46621 tagtgtaaaa aatgcatggt ctaatatgaa gaaatggttt tctgatactt ggcaaagtat
    46681 aaaagattca gccagagaaa aatggaatga aattaaaggt tctattatgt cggttgctgg
    46741 tccattgatt acaggtataa agaatgcatt tttacatgtt actttttatc tagagacctt
    46801 atggaataat ttagttgaga ttggtaaaaa cgtctttgag attttaaaaa atgttatact
    46861 tgcgccggtt ttgtttatta cctccatgat ttctggtgga tgggaagaaa caaaaaataa
    46921 tatgattgct gtttggaata atattaaaga aagtgccata aatatttggg aatctataaa
    46981 gaatatattt gtaagttatt ttacaaatat ttattttgct gcactcaata tttggacagg
    47041 gttcaagctt acattgataa atatttggaa tgaagtggta aatcaagcta aatcgatttg
    47101 gttaaacata aagtattttt ttattaatct ttggattgat ataaaatatt ttgcaattca
    47161 gaaatggatt gaattgaagt tttctattat tcaaacttgg atcgatttaa aatataatgc
    47221 cattactact tggaataata ttaaacagtt tttcaaagat acttggaaaa atattaaaga
    47281 tacggcatac aatacgtgga tttctataaa aaataccatg attaatacat ggaataacat
    47341 taaggactct ttctggaata ttgttactgg aattgttaat tctgctgaaa atgcatggac
    47401 aaatctaaaa aatggtgttt caaatgctat taatcgggta aaagaaatct ttaattcgtt
    47461 aagggaagtc aatttatttg aaattggcaa gaacatcatt gatggactta taaatggtgt
    47521 aaaagaaaag tggaatgctt tgaaagatac tatcaaaggt attgcaggta atatcaaaaa
    47581 ttggattaaa ggagctttag atattcattc tccatcaaga tggatgcgtg atatggttgg
    47641 taaaaatatt gttcaaggta ttatcgttgg tattgataaa gagcaaagta agttagatca
    47701 aaccatgaca aatttagtaa aaacaccgtc tgttcaacct gtagtaaatg gaataagtca
    47761 cctaccaatt acacaaacaa agcaaaatat atctgctagt gaaacaaaag aaattcattt
    47821 acatttaaat gtttatggag atttacctga ttcaatggtt cggaagatta ccacaaaaat
    47881 taaaacagaa ttgacaagac aaatgaaacg agatgctggt gcagtaggag gaacattata
    47941 tgcaacttaa gagaggacaa ttttttatta atcaacatta ttcttctgaa tttaatgtgt
    48001 atattcaaaa caggcctgct tctgtttcag ctagtcgagt aattgaattg agagagcgag
    48061 aaggaaatga ttctatcatt attgataaag gctattacag aaatgtgact agaaagattg
    48121 agtgttacta taaagcacct tcaattgatg tggtgcagga gtgggaagat cgaatcactg
    48181 aatggttaga tatgtcgtct tatagtgatt ttattcttta ctatgatgaa caatatattt
    48241 atcaagctgt agtaatagaa ggacctgaat ttaaaggaac aagaaaaaca ggaaatattg
    48301 tcccttttga atttacagtg agcattcgac catttaagga aaattacaat ggtagattta
    48361 ctattcgaca aacagaaact tttgaaattt ataacccaga gaagtattct tcaaaaccgc
    48421 ttattaaatt gagtggttct ggagatgctt ctttttatat taataaggac aaatatgatt
    48481 tgaaatcgtt ggacagagaa ttatttatag attctaaatt agaagaggct taccgaaaat
    48541 tagatggtaa tttagaacat caggatcaag tcactttatt tttagatttt ccatttttat
    48601 atcctggaaa aaatgaaatt aaatggacga aaaatattca ttcatttgaa ataatgccta
    48661 ggtggtggag aaaagtatga aaccaagaat atatagtcct actgaaacag atttctcaac
    48721 gaatggctta ggaattttaa aggattgtac aagatgtgaa atatatgaag tagctaatgg
    48781 aaaatatgaa ttagagttgg attatccttt aggaactaga tttgatgaat attttgaaaa
    48841 tgactatcaa ataaaagcaa agccaaacga tcaagaagag tatcatatct tttttattga
    48901 tgataaagat atagatactt ttttaaatac agtaactatt tatgctcaga gtcgtacaaa
    48961 tcgacttgga agacgggtag tcactcttgc ggaagtagac tctaaaactg gtcaagaagc
    49021 gatatcaatt attgaaacca aaatggataa aaaatctgac atacgacttt attctgatat
    49081 tacggccgtt tctagcacaa tctttgaagc gagaaatgtt ttaaattgta ttgctggtga
    49141 acaaggatca ttgcttcaat attggggtgg agaaattaaa cgtgaaccat ttaagctttc
    49201 tttgttaaag cgaagaggtc gcaataatgt tggaacgatt cggtatggaa aagatatgtc
    49261 tggtttaaag gtcaaattag attggacagg tataaaaaca agacttattc catatgctga
    49321 tcctcaaagt gaggtaggta cgactaatcg aatttatggt tcgccagtag atagtgccta
    49381 tattaataac tatcctgatg tgtatacaga gcatgttcag tttacagaag aacaaggagt
    49441 aaaagacatt aagagcttaa ataaaatagc taaaaattac tttaaaacga tcaatcctgg
    49501 ctgtgataag cctaaagttt ctattacggt tgaatttgat aagttgactg atagtgaaga
    49561 agcgaaagaa tttgcgaaga ttagaaatta tggtctgttt gatacattta aaatatatca
    49621 taaaaaatat aatatttatc ttgaatcaaa ggttagtgga ctacaatacg attctttatc
    49681 tgaaaaaact ttgaaattag aagcaggaga cattcaagtt gctttttatc agcaacaagc
    49741 tgtaactatt caggataaat taaaagatta tgcaacgaat aattatatga gtgattttaa
    49801 tgattatgtt tcttcaatga ttacaggtca aggcagtgca ggaggatatg taagtttatg
    49861 gccaaaagaa aaaccttcca acatctttat tatggataat ccagatttag aaaaggcaag
    49921 agaagtacta agaatgaata aaaatgggat tgctttttct aagaaaggat ggcgggggcc
    49981 ttttacttca gcttggacat tagatagtat atttaatgcc aattttatac aaactggatt
    50041 aatcaaagca gatatctttc aaaattcttt taacaagact ggagatgtat tgaaattagt
    50101 taatggacta ctccaaattt ggaacaacaa aaagaaaata atggagttaa ctaaaaaagg
    50161 aatggaattt tggaattcta agggttcaat tggaacgatt ggaacaactg attctgctgg
    50221 taatcctttt cctggggctt ctactccaac ccctattgaa gataattctt tagttattcg
    50281 tacaaatgga gacggcaaat atattttgat ttctcctaaa gtaggaaaag gattagtttt
    50341 attaggaaat ggtaaagcaa tttattttgg agacttagat gtacaaggaa aacttacagt
    50401 taaaggaaaa gaaataattc ctggacaagg tggtggtcca tcgggaggtg gagaatctac
    50461 tggtgggtat cctagtgaat taaaaacaga tgcagaaaag agagcttgga gaatttacga
    50521 tattttgtgt aataacggat ttacgaaaca atctgcatgt ggaatattgg ggaacattca
    50581 acaagaaaca ggaggaactt ttgatcctga tactgttcaa ataggtggac cagcatacgg
    50641 attagttcag tgggatggtt cttcatatcc tcttgttggt ccagcaacat gggatggaaa
    50701 agtttatgtt caaaacttat ttaatgctgc aggtattaaa gaaccaataa cgagcttaga
    50761 tgcacaagtt cgattgctta tttggacatt tacaaatgga caatggatgg gcgtagtaca
    50821 acctacgacg gttgatggat ttaaggcctg tactgatcca agacaagcag catatgcttt
    50881 tgaacgaaac tatgaacgtc cggcagcgac acatcctgaa cgtcaagatt atgcagttaa
    50941 ctggtataac aaatttaaag atttaaaacc aggaggagct actggagaag caggactaaa
    51001 acatttagag tctttgattg gacaacgaat tggcaatggt cagtgttatg gcttgtctgc
    51061 agaatattca ggatatctgg gtggttgtgg catgggtgct ggaacaaaat atggtttaac
    51121 tcatgtgata ggaaatactt ctgcagcatc tgatattggt attgcctatg attggtctgc
    51181 tgttggttgg aaagtgattc aaaaccctag atatgatcaa ttagtagttg gtgcaattat
    51241 taattgggca agaggtggac aagtgggttc atggtttgca gacggaactt atggacatac
    51301 tggcgttatc cgaggcttag ctaatggtcg tatgcaaact tatgaacaaa acacagagtt
    51361 aggtatgatt tgtggaaagt tagatcgcca gtattatagt gcaagtgcaa tttcttccat
    51421 tgtcatacca ccaaaatagg gaggtgattt aatggcaaag tggaatgtca tattaagtac
    51481 aacagaaccc tataattacg tggggatgat tcaagttcga caaggcaata aaaacactga
    51541 agttatggaa gctacaattg tcgaaaatgg tcttccatat gatttatcag aatgtaaggt
    51601 atattttgaa tcagttgttg gcggaaaata tccagtccaa ttagaaacaa gaattgtgga
    51661 tgctaaaaaa gggaaaatca aatatatttt tgataaatat tccatgcagt gtttgcatcg
    51721 acaaacagcc aatttcatta tatttaaagg agaagacttg attggaacaa ctcaagactt
    51781 ctcctatttt gtcatcaatg ctgtttcaaa aacagaagga gaaatgggtt cttattggca
    51841 atcaattgaa gatttaattg ctgatatgac agattttatt aatgaaaata aaggcgattt
    51901 tacggactgg atgaatgaaa ggaaagaaga atttgatcgc tggagagaag aacaggagaa
    51961 tagtttccaa gattggagag aaggacaaga atcagattat ttgtcatggt ttgaatcaat
    52021 caaggatatt ttgaagtcta tcgatccagg tggagtaatg ttagccgaat taatggatgc
    52081 acgtgtagat cttcaaggtg tacgccatga atcgatttct gaacgtttcc tatccgatct
    52141 aaattatttg tatcaaaaaa tgaaagcagc acttttcacg attgaatacg gtgaaattga
    52201 agtgactgat attcttcaag acgatctctt ttcagataat cacgaagtcg aaaaagttgg
    52261 aactgtagaa ttcccgattg aagaaggagc cttgatcatc gcaaccgttg atgatccaaa
    52321 gcaaaatgtg ttcactcttg agaaagtcgg ggtgatctaa tggctaaaac taaacgaatg
    52381 atggaaacgg atgaaaaaac aggtgtacaa cgccaattct ttccaatcac acatgcttcc
    52441 gcagttcttg ggttagaaga aataatagca ggagaagcaa cagttttatc tgttaatgga
    52501 aaaattggag ccgtcgtcat tactaaagaa gatttgggat tagagaatgt tctcacagaa
    52561 ttaccctatg caagtgaaga agatgacggc attatcacgg cagaaatgta tcaaaaaatt
    52621 ttaaacagtg gagaaggtga ctacgtgttg ccagttgcca ctatcgaccg tttgggtggc
    52681 ataaaagttg gtgaattatt gacgattgat gagacaggga aagtctctgc agtcagacaa
    52741 tctgatgtca atttttcgct ggagttaaaa gaaaaactcg attcactgaa aaattatact
    52801 gctggagaaa acatcactat tgatgaagat ggaacaatta gttctacagg tggtagtggg
    52861 actggtggtg tcaatcagtc atatgtagat caaaaattcc aagaagctgt aaatcaagca
    52921 gaaaattaca caaacgaaag aattccaaat tttacttttg aaaaaattgg ggaggtatag
    52981 agaatgacag atatcgtaaa aataaaacaa agcaatgtac aggtttatcc acaaactcat
    53041 tggaatgcta tagaaggcaa accaacaacg gtgaagggag ataaaggcga tcctggccaa
    53101 gcagcaacaa ttaccatagg aaccgtttct agtggttcaa ccgcttctgt tacgaatgta
    53161 ggaacatcat ctgcagctag atttaatttt gttttaccaa agggagataa aggtgatcct
    53221 ggaataaatg ccacaactac agctgtagct acaactacag caaatgggtt gatgtcgtcc
    53281 acagataaaa ctaagttgga tggaattgca gctggagcac agaaaaatcc aggtaatgct
    53341 acaactacga cagcaggttt aatgtcagca accgataaag tgaaacttga tggattagcc
    53401 aatattacat ttgagaaagt ggggacggtt taatggctga tattgttcaa ttaaaagaag
    53461 acggagttgc taaatactta aaaacgcatg taaaagctat tgatggtaaa gaagcattgg
    53521 tgcagacaga tggagaccaa gccattgcag gacataagaa tttttcaggt tctgtaacaa
    53581 tcaataataa acgtgttttg acgactgatg ataacagata tgaagtggta aatctggttg
    53641 tcactaacgg taatacaggg acagcaaagc tttatcgtga aggaaaaaca gtttctatat
    53701 attttgtggc tttaaacgga aaaagtagtg gcgggaatga ttcggttatt ttaactgttc
    53761 cagaaggcta tcggacacca attagttttg aacaactggt tgggtcaata gaccgttcta
    53821 ctttgaacag tgctcaacta tctattggcg cagacggagc cattaaatgg agaagaaatt
    53881 caagttatgg atcagcttat tcatttgtta tcacttattc aatttaaggg aggaaatcta
    53941 atgaaagtag tttacaaatc aatcaagcct tacggattcg agcaaatcat tttgaacaat
    54001 caagaaaata tccctgaaaa ctgtacagag attaaaccac cagttcctaa ctggagacca
    54061 agatttgatt ttgataaaaa acagtgggtt gagttagcta ctgaagaaga gaagagtggc
    54121 acagcggttg acgatattga agatgtcgat cagttgaagc aattaaatgc tctactgaca
    54181 aaacaattgg cgatatcggt acaggaacaa gaaaaaatgc aacaaatgtt agctcaattg
    54241 acgatggaag tcgcaagtat taagaatgga gggaaaagta atgaatagtt ttccgggctt
    54301 tgaaaatata aaacaatttt atgattgggg atgttatacg gaccaagatt tacttgacta
    54361 tgtaaacatg aactgtttaa caaaagacca atataagcag attactggaa atgaaattta
    54421 attaagcaca aagttaaata aaaagcgtac tcaaacgagt gcgcttcttt gcataaagga
    54481 gaaatagata ttggaaaaat atttaaatac actctcagta atgacagggg tgataggcgg
    54541 gacaattgtt ggtttattgg gagggatgga caatatacta catgttttaa tttttcttgt
    54601 gggtgtggac ttcttaactg gacttgctaa ggcatggaaa ttgaaagaaa taagtagtga
    54661 gataggtttc gaaggattgt tgaagaaagt cttaatcttc gttgtgattg ccgttgcggt
    54721 tgacgtacag aaaatcgttg ggaattctat acctctaaga gaaatagtta ttatgttcta
    54781 tgttgcaaat gaagggatta gttttttaga aaacatttcg gtattccttc ctttgccaga
    54841 taagttaaaa gaggtattcc aacaaatacg aaatgatact gaaaataaag accgaggagg
    54901 aaccaaatga aaaagaaaat ctttgtagga gctattatag ctcttttttt attgccaata
    54961 aacgcctttg cttactcgat caacaatgaa ttcaatttgg gcgcaaacga aggtagttct
    55021 caagtagcaa ataaccaata catcctattg catgaaacag caaacgaaac tgcgacagga
    55081 cgaaatgaag cgcagtacat gaaacgttct tggtacaatg cctatacagc gtatattgtt
    55141 ggcgatggtg ggatcgttta ccaagttgga caacctggtt atgtacaata tggcgctggt
    55201 tcatatgcta atgcaaatag tcctgtgcaa atcgaactgc aacatacgca cgataaagta
    55261 acgtttgaaa agaactacaa ggcatatgtt gaattagcga gagattccgc taataaatac
    55321 ggtattccac ttacattaga cacaccgtat aatcaaccag gaatcaaatc acatttatgg
    55381 gtaactcaaa acatttgggg cgatcacact gatccgtatg gatacttatc agaaatgggt
    55441 gtaagtaagg aaaaactggc ttacgattta gctcatggat ttacagacga aaacccaacg
    55501 acttctgaga acaagcctgt cattgatcca acccgagcag gtgcagcaaa tccaacttta
    55561 tcagatggaa cgaaccattc tcacattgat cagtttggag aaatcgaaaa tgcgaactta
    55621 cacgtcgctg gatggcacat cgctaactat aaatacgagt atattttcat tatggactac
    55681 aatactggga aagaattagc tcgagtaaga gctgatggaa tttatagacc ggatgtaaat
    55741 caagcttata atacttctgg aaacgttggc tatcatgtat cttttaacat gcgcaatttc
    55801 cctaataaga aagtatacgt catgatgcgg gcaacgaatg atccagaagg aaacactaaa
    55861 ggcggtgcgc aagatttcca tgacaaacgt tggtatttaa atattcctaa acgataaaaa
    55921 tagctcctcg ttgaggagca gtacatagaa ttgaaaatta acgttaaatc aaaaaaatat
    55981 ttacaagatg tttatttaag tagataataa aagaaaaaag caggtgaaat tgtgacagca
    56041 gaaattggta ttatgaataa aagtggaatc gtgttagctt cagattcagc atctacgatt
    56101 ggagatagca aagtatataa tactgcaaaa aaattattta ctttggattc catgcattct
    56161 gtaggtatca tgatatatgg taatgctgaa tttaatggta ttccttggga aataatcatt
    56221 actcaatata agaaaagcat tggtagttct gtttttaata ctttggaaga atacgcggat
    56281 aattttatag aatttgtcaa aacagcatct tttattagaa gtgaacagac cgagcaagaa
    56341 caaatgattg gggtttttca aaaaataatt tcaggtttat ttgagagtat agaagtagat
    56401 attaactttt taataagcca aggtacacaa atagacaaag atgtcctagt gaagttatta
    56461 caaacaaaaa tgaataccaa tttgtctcaa cagtcccaga cattcatttt agatattgaa
    56521 aaggcgttat ttcttagtaa ctatggagaa atattaaaag atattcttaa tagtatttct
    56581 acaatggaag gtgtttcaga agctatatca gaggaaattc aaagttacgt ttatgaaatt
    56641 ataattagag acgatgttta ttcttcccct acaggaatag ttatagcagg atatggaaga
    56701 atggatattt tccctaaact atattcttat aatatgtttg gatttgttat gaatattctg
    56761 aaatactcag aatatgaaag tgctcaaata ggaaatgaca atggttcatt aagatctact
    56821 atattaccat ttgctcagtc tgatgtggta aatactgtag ttcaaggggt agatccacaa
    56881 attactaatt atctgtcgag tcaagtcgat agttttgacg ataacggaaa aaatacctat
    56941 attaatatta taaagaatat ttcagagttt caacaaaatc aattcatatt tccgttacta
    57001 aacatgattg ctttactccc agttgaagaa acagcaatta tcgcagagac tttattaaat
    57061 ttaaccagtt ttaaacgaaa atatactact tctgtagaaa cagtaggtgg cccaattgat
    57121 gttttagcta ttacacctaa tgatggccct atttggatta aaagaaaaca ttattttgat
    57181 attgataata atattggata cagattgcga aaggagagag cgaatgatta caataattaa
    57241 acctcaggaa aaatcccctg ttttgaaatt taatgagagc aatctagccc ataataaaat
    57301 gagtataact gatacagtat ttgatgtaat ggttgagcaa caaaaaaaaa ttaataataa
    57361 caatagacaa agaaaagaaa ttaaccaata ttaatgtttt ttctgttgcg ttttttgcag
    57421 tcataattta aaacctcgct caatcttggg cgaggtcttt ttttattttt ctgaaaagtt
    57481 aaagtaaata atagcataaa ataatatatt ttacaaagaa taagtacaat ctagtttttt
    57541 gctattaaat gtgtaataat aaatatgcca tcacaacatg aagaatgaaa tccattatta
    57601 tctagtctag tccattcttt ttgtttgcag tatttgtgat ggctttc
//
LOCUS       DACGLI010000010        57516 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.010, whole genome shotgun sequence.
ACCESSION   DACGLI010000010 DACGLI010000000
VERSION     DACGLI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.010"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(61..2424)
                     /locus_tag="IXT22_000689"
     CDS             complement(61..2424)
                     /locus_tag="IXT22_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAQ4862075.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="IXT22_000690"
     CDS             2872..3093
                     /locus_tag="IXT22_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862076.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="IXT22_000691"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="IXT22_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAQ4862077.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="IXT22_000692"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="IXT22_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAQ4862078.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="IXT22_000693"
     CDS             complement(5894..6205)
                     /locus_tag="IXT22_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAQ4862079.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="IXT22_000694"
     CDS             complement(6202..6495)
                     /locus_tag="IXT22_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAQ4862080.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="IXT22_000695"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="IXT22_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAQ4862081.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="IXT22_000696"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="IXT22_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAQ4862082.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="IXT22_000697"
     CDS             complement(8333..12685)
                     /locus_tag="IXT22_000697"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAQ4862083.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="IXT22_000698"
     CDS             complement(12897..14606)
                     /locus_tag="IXT22_000698"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAQ4862084.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="IXT22_000699"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="IXT22_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAQ4862085.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="IXT22_000700"
     CDS             complement(16103..16903)
                     /locus_tag="IXT22_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAQ4862086.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="IXT22_000701"
     CDS             complement(16900..17712)
                     /locus_tag="IXT22_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAQ4862087.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="IXT22_000702"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="IXT22_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAQ4862088.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="IXT22_000703"
     CDS             complement(18467..19189)
                     /locus_tag="IXT22_000703"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAQ4862089.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="IXT22_000704"
     CDS             complement(19325..20206)
                     /locus_tag="IXT22_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAQ4862090.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="IXT22_000705"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="IXT22_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAQ4862091.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="IXT22_000706"
     CDS             21446..21925
                     /locus_tag="IXT22_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAQ4862092.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="IXT22_000707"
                     /pseudo
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="IXT22_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
     gene            23226..24011
                     /locus_tag="IXT22_000708"
     CDS             23226..24011
                     /locus_tag="IXT22_000708"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4862093.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="IXT22_000709"
     CDS             complement(24357..26048)
                     /locus_tag="IXT22_000709"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAQ4862094.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="IXT22_000710"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="IXT22_000710"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAQ4862095.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="IXT22_000711"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="IXT22_000711"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAQ4862096.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="IXT22_000712"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="IXT22_000712"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAQ4862097.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="IXT22_000713"
     CDS             30332..31033
                     /locus_tag="IXT22_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4862098.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="IXT22_000714"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="IXT22_000714"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAQ4862099.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="IXT22_000715"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="IXT22_000715"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4862100.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="IXT22_000716"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="IXT22_000716"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4862101.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34439)
                     /gene="tsaB"
                     /locus_tag="IXT22_000717"
     CDS             complement(33615..34439)
                     /gene="tsaB"
                     /locus_tag="IXT22_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAQ4862102.1"
                     /translation="MYHCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDKIIVPMFDARRKNVYAGAY
                     RWKENRLEIVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFYEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="IXT22_000718"
     CDS             complement(34528..35508)
                     /locus_tag="IXT22_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4862103.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="IXT22_000719"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="IXT22_000719"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAQ4862104.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="IXT22_000720"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="IXT22_000720"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAQ4862105.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="IXT22_000721"
     CDS             38266..38433
                     /locus_tag="IXT22_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAQ4862106.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="IXT22_000722"
     CDS             complement(38495..40306)
                     /locus_tag="IXT22_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAQ4862107.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..40668)
                     /locus_tag="IXT22_000723"
     CDS             complement(40303..40668)
                     /locus_tag="IXT22_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAQ4862108.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40831..41226)
                     /locus_tag="IXT22_000724"
     CDS             complement(40831..41226)
                     /locus_tag="IXT22_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4862109.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41244..42206)
                     /locus_tag="IXT22_000725"
     CDS             complement(41244..42206)
                     /locus_tag="IXT22_000725"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAQ4862110.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42206..42418)
                     /locus_tag="IXT22_000726"
     CDS             complement(42206..42418)
                     /locus_tag="IXT22_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAQ4862111.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42439..43137)
                     /locus_tag="IXT22_000727"
     CDS             complement(42439..43137)
                     /locus_tag="IXT22_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4862112.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43157..43699)
                     /locus_tag="IXT22_000728"
     CDS             complement(43157..43699)
                     /locus_tag="IXT22_000728"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAQ4862113.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43831..44835)
                     /locus_tag="IXT22_000729"
     CDS             complement(43831..44835)
                     /locus_tag="IXT22_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4862114.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44832..45821)
                     /locus_tag="IXT22_000730"
     CDS             complement(44832..45821)
                     /locus_tag="IXT22_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4862115.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45818..46624)
                     /locus_tag="IXT22_000731"
     CDS             complement(45818..46624)
                     /locus_tag="IXT22_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862116.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46790..47746
                     /locus_tag="IXT22_000732"
     CDS             46790..47746
                     /locus_tag="IXT22_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4862117.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47823..48341)
                     /locus_tag="IXT22_000733"
     CDS             complement(47823..48341)
                     /locus_tag="IXT22_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4862118.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="IXT22_000734"
     CDS             complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="IXT22_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4862119.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48806..49252
                     /locus_tag="IXT22_000735"
     CDS             48806..49252
                     /locus_tag="IXT22_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4862120.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="IXT22_000736"
     CDS             complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="IXT22_000736"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAQ4862121.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51667..52641)
                     /locus_tag="IXT22_000737"
     CDS             complement(51667..52641)
                     /locus_tag="IXT22_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4862122.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52977..53064)
                     /locus_tag="IXT22_000738"
     tRNA            complement(52977..53064)
                     /locus_tag="IXT22_000738"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53030..53032),aa:Ser,seq:cga)
     gene            complement(53209..53775)
                     /locus_tag="IXT22_000739"
     CDS             complement(53209..53775)
                     /locus_tag="IXT22_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4862123.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54030..55361
                     /locus_tag="IXT22_000740"
     CDS             54030..55361
                     /locus_tag="IXT22_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAQ4862124.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55327..55677
                     /locus_tag="IXT22_000741"
     CDS             55327..55677
                     /locus_tag="IXT22_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862125.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55769..56188)
                     /locus_tag="IXT22_000742"
     CDS             complement(55769..56188)
                     /locus_tag="IXT22_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAQ4862126.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56189..56533)
                     /locus_tag="IXT22_000743"
     CDS             complement(56189..56533)
                     /locus_tag="IXT22_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAQ4862127.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56883..57479
                     /locus_tag="IXT22_000744"
     CDS             56883..57479
                     /locus_tag="IXT22_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4862128.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16181 a        12116 c        10051 g        19168 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgta acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag ttgtttcctt
    40681 ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa aaaaaatgaa
    40741 cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat gattgattcg
    40801 gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga tttttccaga
    40861 ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt tacgtaattt
    40921 atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag gctggtcttt
    40981 tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg cacctaaaat
    41041 atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt ttctcattcc
    41101 ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta ctcgtagata
    41161 gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa ttacccataa
    41221 aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc agcaccaatg
    41281 acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct tacttgcggg
    41341 aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc tgctgccgat
    41401 actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt ggcgcaagct
    41461 aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc gtcttcttga
    41521 gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat tgctttcagt
    41581 tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac accagtagcg
    41641 ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc ttcaggatcc
    41701 acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa atttccgcca
    41761 gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc tggatcgttt
    41821 tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt atcgatagcg
    41881 aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc tgtccagttt
    41941 aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg ggtacccatg
    42001 ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg gttgattgat
    42061 tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc gatgctccat
    42121 ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt tccacctaaa
    42181 tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt tcttcaattc
    42241 ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca atcaaacggc
    42301 tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg cgtgcaccca
    42361 catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag ctctccatct
    42421 ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca gtaaaataca
    42481 tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta tcgaatagct
    42541 tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa ttagcccacc
    42601 gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg tcaacacaat
    42661 aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa aatgaaaccc
    42721 taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac cagacagaac
    42781 attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga acatataaat
    42841 caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa aatacagtat
    42901 cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg tcactaaacg
    42961 ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat aagggatctc
    43021 aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta aaaaagcata
    43081 ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat aattcatgaa
    43141 aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca aagctctccg
    43201 gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt ttatgaaaat
    43261 tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg gctctattgt
    43321 agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc ttctctgatt
    43381 gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc atttcataaa
    43441 acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt tctttttctg
    43501 ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc gtccctatca
    43561 cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc tgttcttttt
    43621 cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc cggcgtaatc
    43681 ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt ataggaaaaa
    43741 aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa gaagacctag
    43801 aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt tttgtctgat
    43861 aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc ctgtaggtac
    43921 ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa aaatggaacc
    43981 gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta gcttcgcagc
    44041 atgaggagct agtagtccta caaaagataa actacctgtc accgctacac taccgcttgc
    44101 caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa ggcctaatcc
    44161 ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa gtcctcctag
    44221 cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc tcgcacccca
    44281 gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata attggatcgt
    44341 gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca ataagattcg
    44401 attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc aagcagctaa
    44461 aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt gcgaaaagaa
    44521 acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata tactagaatc
    44581 tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa gacaagctcc
    44641 tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca gcgccaaaga
    44701 agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa aaggcgtacc
    44761 aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat agaacgtcca
    44821 atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg aacgccaatc
    44881 aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct cgctgtaaaa
    44941 tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac ataacgatag
    45001 tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa tgaaacaggt
    45061 ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac aatcaaccgc
    45121 gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg aatcaaagat
    45181 attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg aaacaatact
    45241 gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc aagatcctgc
    45301 tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga actaatagct
    45361 acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg caaaaaacca
    45421 aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac agaaaaatca
    45481 gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc cgcgttgatt
    45541 cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa tgcaccgctc
    45601 aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg aatatttcgt
    45661 atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca aaaatctgct
    45721 tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa aagaacaaaa
    45781 cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc tcctgctctt
    45841 ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc gtgacaatcg
    45901 ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct tcaggtgtac
    45961 cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa cgtgaagcat
    46021 gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg atttcagtca
    46081 ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt tcatccaaga
    46141 tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg gtttgtccac
    46201 cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca tccaacgccc
    46261 actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga taagggtatc
    46321 gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta gtttgtgcta
    46381 ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca gagttattga
    46441 caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat aaagtagatt
    46501 ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc gtaacagaca
    46561 tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct cttaatctcg
    46621 tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt tcaacatttc
    46681 gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt cgaaatatca
    46741 ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa tgaaattaaa
    46801 aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga gcgcttgctc
    46861 cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat ccaatagtac
    46921 tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc ccaaacggat
    46981 catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta tcgcccagtg
    47041 gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg atgtcccaac
    47101 gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt tgctgttgat
    47161 ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa tcgcgccaac
    47221 ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag atgtcggcaa
    47281 agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa aatccatcaa
    47341 gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag tgttgtgggt
    47401 gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa tcgtatacga
    47461 cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag ccacttctga
    47521 ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca tcatccttgt
    47581 gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc ttaaagcagt
    47641 gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata acggacctat
    47701 tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt aactaaaaaa
    47761 agaatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta gacgcataga
    47821 ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg aaaacgatgg
    47881 gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc gaagtctgaa
    47941 aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa tgttcgccag
    48001 atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga aacatagata
    48061 tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat tacttccgca
    48121 ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg ataaggaagt
    48181 gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg atccattgta
    48241 tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc atttttgccg
    48301 atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc tccttatgat
    48361 tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa ttgagaactt
    48421 taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg gcaatatttt
    48481 tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata gttacgttct
    48541 ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc catttttaca
    48601 agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt ctagattgct
    48661 agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac ggttttactt
    48721 ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat atagattatg
    48781 ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc ctgcatcaat
    48841 gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg cattattaga
    48901 tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa aaaaatggta
    48961 tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc caagcaagac
    49021 ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg tgatcgtaga
    49081 atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa gcaaccattt
    49141 tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca aagaatcaac
    49201 tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt gaacatatgt
    49261 aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa tggtgttcct
    49321 ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg ttttttgaaa
    49381 ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat tgatatttga
    49441 ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt catctacaaa
    49501 gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt gctcttcttt
    49561 acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa aaaattcttt
    49621 tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt ctttcaacca
    49681 agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt ccggaagatg
    49741 tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata aaaacttact
    49801 tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc ggacttccaa
    49861 agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca tccattgatg
    49921 aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt tctcgtaatg
    49981 aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta acacttctga
    50041 tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg caggagcaag
    50101 tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt tacgtcctaa
    50161 attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac ggatgaattt
    50221 tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg ccccttctcc
    50281 agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca aaggtacgca
    50341 agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg ctttgaacga
    50401 catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg ttagttttct
    50461 ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag aatgatctgg
    50521 tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag aaccaacttc
    50581 tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga ttttttcgat
    50641 ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat attgctgaat
    50701 gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat agacatcttt
    50761 gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt tcaacgcttc
    50821 tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt ctgaaccaaa
    50881 cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt ggtctcttgc
    50941 accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc cgcggatctt
    51001 ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg tatctgcatg
    51061 tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt aattatagat
    51121 ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct gagtaccgcc
    51181 ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat cgatatattc
    51241 tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa taattgtttt
    51301 tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt cacatcctaa
    51361 tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat agcggacgaa
    51421 tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc tgtttttaca
    51481 gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta ccttattctc
    51541 ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa aaaagacacg
    51601 acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa cggatctatt
    51661 cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac tgaccaattc
    51721 atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt cttcatacgt
    51781 acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg tatattcgta
    51841 ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta gtatatgaaa
    51901 aaattgactg atactttcag attctgaatc acctgatgca gcattcattt tagtaaatgt
    51961 ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc ctcccatccc
    52021 acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg ttccatttga
    52081 tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat tatttgtcaa
    52141 cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa ttactatcga
    52201 tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt cactaaaatc
    52261 gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg ttgagcattg
    52321 ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt cttgtaattc
    52381 tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt tttcatttgt
    52441 agcctcataa tagagtggat agttggatac cccagctgct attcctatca ttgcataatg
    52501 tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag taatagtgac
    52561 tacttcatta taagacatct cataatcaaa attccttcca aaataatggt ctttcgttgc
    52621 ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt acacttttat
    52681 cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat ttactagcat
    52741 ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag tacaacaata
    52801 aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt gttcaaaagc
    52861 ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat ttttgtttgg
    52921 ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt gatataagga
    52981 aggtacagga tttgaacctg cgcgccggta ttagccggtt cgccggattt cgagtccggt
    53041 gcattaccac tctgccaacc ttccgtaagt actattttta aacttttttc acgaaatgtc
    53101 aagcctattt ctaatagata aataacagaa atcgcttttt ttagcaaaaa agtccattga
    53161 cagtttgcag ccaacggact taccgatcaa attcatactg atagaacact atctgattat
    53221 ttcaggatta tctaatgcta aaatcgagtc aattgtccgt ttgatcagtg caatgatttg
    53281 ttcttctgtt ggatgcatga tgtttgatga catcaatgac gctaagccag tcactgctac
    53341 ccatgtacca gtatgcagag catcgacata ttcatccgat aattgattgt atctttcatc
    53401 ttctttaact atttcacgga aataattgta tgaaaaatca tgcattttct ttccgtcccc
    53461 atgttcatca atgtacaatg ccatgtaaag actatgatgc ttttttgcaa agtagatata
    53521 gttcaaaccg agatcaatga ttttatcacc agtacgttca atagggaaaa catcttcttt
    53581 tagttgttca aagatagaat ccagcaacgt attttttaaa tcttccatgt ttttgaattc
    53641 cagataaatc ggctgtgtcg aaatccccat ctttttagca atatttctcg cagtaaatcc
    53701 tttaaaccct tcctttgcaa caacatcata agcagctttt agaatttgat ccttggtata
    53761 gacttttctt ctcattaaaa ctcccccact tctttactgc agtatatgtt gttttattgt
    53821 accctatttt tagcattttt tgcaaacatt ttactcaaaa cgttatattt taaatttttt
    53881 tcagtcttct ttaacttttt tttgcaaaat taaaaaaatt tggttaaatt caatgggttc
    53941 ccttacattt ttagttttga cctaaatgat agttgtccaa atctttcatt tcaagttata
    54001 gttaaagaaa atgaaaaaga aggtgtgtaa tggaaaacga aactgacgtt atttatattc
    54061 atcctcaaaa acgaatcgtt tcacagaaaa gaaagtattt ttatcttggt tttacaggtg
    54121 ttttttttct ttttattggc ttgctttcta atactcctac tgataattgg agtggattgc
    54181 taactattct tacctcgcca agcaatcttt tgacagatta ttttgcttta ggtgttttcg
    54241 gaagcgcatt cataaatgta gggattttga ccttactttc tgtgctttta gcttatcggc
    54301 acaaggtgat tttaaacggt cccttatttg cttcgattct aacagttacc ggtttctctt
    54361 tttttggcaa aaacctttat aattctatct caatcatttt aggtgtgtat ctatacgctg
    54421 tatttgtcaa taaacctttt tctcagtaca tcatgatcgg actgtttggt agcgtattat
    54481 caccggtcgt tagttatatc acttttggta tgcgttttcc tttactgata ggtattttat
    54541 tggggaattt agctggcata gcaattggta tacttcttcc gcccttagct gctcaaactt
    54601 tagttttcca tcgtggattc acactttata atattggatt cacctctggg ttgattgcga
    54661 tgacttttac tgctgttttg aggttattca gctattcaat cgtcgaaaat acattggttt
    54721 tcaatgaata tcactttcct ctcatttgga ttatttttgg ctttttttcg ctgacagtcg
    54781 gaattggttt ctattataat tcctttcggc tttcggggat tcgagaaatt ttcgattcat
    54841 ctggaaaatt gacaactgat ttcattgcta attctggtat tggtgctact ttgatcaaca
    54901 tgggcttagt tggtctgatg ctgtcttctt atgttttgct ggttggcggt cagttaaatg
    54961 gacctgtcat cggtgctatt ttatctgcgg tgggtttcag tgcttttggt tgtcatttaa
    55021 aaaacagttt tccgatacta gtcggaatat ttattgcttc tttgtttgga acttttcatg
    55081 agatcaccag tactggcatg cttgttgcag ctgtgtttgg gacaggtctt gcgcccataa
    55141 gcggttttta cggcagtttt tacggtgtaa tagctggtgt gctacatatt gctcttgtcc
    55201 ataacgtcag cactttgcac ggaggactaa atctatataa cagtggtttt tcaactggtt
    55261 tcgttgcagg tatccttgta ccgatactag ataactttac cgctgtcaga aaggaaaaaa
    55321 agacacttgg aaaaagaatt atcaaaaaga atcatcgatg agcttcttac ttatttatat
    55381 tcccatgaaa taactgaaat acgtattgga gtagaatttg ctgaggaagg gcttttcata
    55441 gagatacagg gtacggcaga aactcagcca gaagatttag atgtacttgc tgatttgctg
    55501 aacaatcctc gggaccctag tatggaaatc tactatcaag aactattagg taatccccga
    55561 catgatcggg aagattatca tctgttaggt agtttgattg atgacgtgga aatcatgtat
    55621 gcccagccga ttatcaatat taagatcttt cgacgtgctt ctcattccta ttattaaccc
    55681 tattttctat ttataaaaga ctgaatcaaa aaagcagctc ctgaaagttc gattaaaatc
    55741 tactttcagg agctgttcaa gcttgacatt attgattttc caatccttca tacacttcat
    55801 ctgttacagg ttctaaaaac tctgaattac cagcagtgat cgccaaatgt tcaaaccaac
    55861 tgtcttttgt cgcaccatgc caatgtttaa tccctttgtg cgttacgacg acatctccag
    55921 ccattaatcg tcttgctggc tttccttctt cctgatacca gccttctcct ccggtcacaa
    55981 gtaagatttg atagccgtct gtatggacat gccagtgatt gcgacaacct ggttcaaaag
    56041 ttacattacc tacaccaaca gaaacttcgg gatcattcac taacatattc agatagcttt
    56101 gcccggtaaa tacttgagcg taagcttcgt ttttttcacc tgctggaaaa atcacgccat
    56161 tgtgtatttc ttcgtgtttt gtcatcattt acgcctcttt cttatcttcg ctattttctt
    56221 ctaaatagat ttcttttgct aaactaaaag ctgaccaagc ttttggccat tctacataaa
    56281 aagctaaatg ggtaatgatt tctgctattt cttcactagt aatgccattt tgcttgccaa
    56341 tcttcagatg agctggcaat tgttcaaaat ttcctcctga aattaatgca gatatggtga
    56401 tgatactacg ctgatgagca gataattctt ctctggacca tacttgtcca aataaaacat
    56461 catcatttaa ttctgcaaat tttggtgcaa aatctcctaa ttgatctcgt cctgcggttt
    56521 gtttttctgc catttctctt attctccctt cacgactgtt aggtgattca actatggttc
    56581 taaggcaact ttattttcta ttgtttcttc gcatttcatt ttaaatgtag tctttcagcc
    56641 tgtccaatgc ttagtttatt cagtcgatat gctttttaag catagttgct aacgcttttt
    56701 ttattttaaa aaaaacaagt tattaaataa gtctttagtt ggatgttttt ttgagatcaa
    56761 tcttttatac ttatgatgaa cttacaaaat tgtttgtttt ctgtcatatc aaaaaatggc
    56821 gcagttagtt gcttttctag taaagtatag ttaacaaaga acctctaagg agttgatgaa
    56881 taatgaatat tgctgcctct cgaaaactga taaatttcat atccattatc ggattaggcc
    56941 tatcaatcgc gctgacgatt tattttatta atttaggtgt tttcaaagat ttgaatgcgt
    57001 taagaggatt agtaggtgat tccatcattt taggaccgat tatttttgtc ttcatccaaa
    57061 tcctgcaagt agttattcca atcattcctg gagggatcag tactgcagct ggtgtcctga
    57121 tatttggccc ttatgctgga tttatctata actatattgg aatctgcatt ggttcgatta
    57181 tcatttttct gctagggcgt cgttatggaa agccattcat actttccatg attagcgata
    57241 agacatataa caaatatatt ggctggctgg ataatcaaaa ccgttttgag aagctgtttg
    57301 ctctagctat ttttcttcca gttgctcctg acgatgcgtt atgtttgatg gctggattga
    57361 caaacatgtc agtgaaacga tatacactaa tcattttgat tgctaaacca ctgtcgattt
    57421 tcttatatag tatggccttg atttatggag gtcaatatct aagtggtctt cttggataat
    57481 atttattttg taaaattagt cattgattga caatgt
//
LOCUS       DACGLI010000011        56470 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.012, whole genome shotgun sequence.
ACCESSION   DACGLI010000011 DACGLI010000000
VERSION     DACGLI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.012"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(38..2488)
                     /gene="parC"
                     /locus_tag="IXT22_000745"
     CDS             complement(38..2488)
                     /gene="parC"
                     /locus_tag="IXT22_000745"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAQ4862129.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(2500..4545)
                     /gene="parE"
                     /locus_tag="IXT22_000746"
     CDS             complement(2500..4545)
                     /gene="parE"
                     /locus_tag="IXT22_000746"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAQ4862130.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(4711..5145)
                     /locus_tag="IXT22_000747"
     CDS             complement(4711..5145)
                     /locus_tag="IXT22_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAQ4862131.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            5272..5910
                     /gene="plsY"
                     /locus_tag="IXT22_000748"
     CDS             5272..5910
                     /gene="plsY"
                     /locus_tag="IXT22_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAQ4862132.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(6042..6917)
                     /locus_tag="IXT22_000749"
     CDS             complement(6042..6917)
                     /locus_tag="IXT22_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAQ4862133.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(6999..7790)
                     /gene="codY"
                     /locus_tag="IXT22_000750"
     CDS             complement(6999..7790)
                     /gene="codY"
                     /locus_tag="IXT22_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAQ4862134.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(7808..9208)
                     /gene="hslU"
                     /locus_tag="IXT22_000751"
     CDS             complement(7808..9208)
                     /gene="hslU"
                     /locus_tag="IXT22_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAQ4862135.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(9222..9770)
                     /gene="hslV"
                     /locus_tag="IXT22_000752"
     CDS             complement(9222..9770)
                     /gene="hslV"
                     /locus_tag="IXT22_000752"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAQ4862136.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(9807..10712)
                     /gene="xerC"
                     /locus_tag="IXT22_000753"
     CDS             complement(9807..10712)
                     /gene="xerC"
                     /locus_tag="IXT22_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAQ4862137.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(10910..12286)
                     /gene="trmFO"
                     /locus_tag="IXT22_000754"
     CDS             complement(10910..12286)
                     /gene="trmFO"
                     /locus_tag="IXT22_000754"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAQ4862138.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(12255..14333)
                     /gene="topA"
                     /locus_tag="IXT22_000755"
     CDS             complement(12255..14333)
                     /gene="topA"
                     /locus_tag="IXT22_000755"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAQ4862139.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(14455..15312)
                     /gene="dprA"
                     /locus_tag="IXT22_000756"
     CDS             complement(14455..15312)
                     /gene="dprA"
                     /locus_tag="IXT22_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAQ4862140.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(15368..16135)
                     /locus_tag="IXT22_000757"
     CDS             complement(15368..16135)
                     /locus_tag="IXT22_000757"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAQ4862141.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(16128..16988)
                     /gene="ylqF"
                     /locus_tag="IXT22_000758"
     CDS             complement(16128..16988)
                     /gene="ylqF"
                     /locus_tag="IXT22_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4862142.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            17248..17646
                     /locus_tag="IXT22_000759"
     CDS             17248..17646
                     /locus_tag="IXT22_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4862143.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            17883..18425
                     /locus_tag="IXT22_000760"
     CDS             17883..18425
                     /locus_tag="IXT22_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4862144.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(18508..19059)
                     /gene="lepB"
                     /locus_tag="IXT22_000761"
     CDS             complement(18508..19059)
                     /gene="lepB"
                     /locus_tag="IXT22_000761"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4862145.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(19211..19438)
                     /locus_tag="IXT22_000762"
     CDS             complement(19211..19438)
                     /locus_tag="IXT22_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4862146.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(19435..19953)
                     /gene="msrA"
                     /locus_tag="IXT22_000763"
     CDS             complement(19435..19953)
                     /gene="msrA"
                     /locus_tag="IXT22_000763"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4862147.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(19973..20686)
                     /locus_tag="IXT22_000764"
     CDS             complement(19973..20686)
                     /locus_tag="IXT22_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4862148.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(20689..21585)
                     /locus_tag="IXT22_000765"
     CDS             complement(20689..21585)
                     /locus_tag="IXT22_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4862149.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(21743..22585)
                     /locus_tag="IXT22_000766"
     CDS             complement(21743..22585)
                     /locus_tag="IXT22_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4862150.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            22717..23370
                     /locus_tag="IXT22_000767"
     CDS             22717..23370
                     /locus_tag="IXT22_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4862151.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(23433..23960)
                     /locus_tag="IXT22_000768"
     CDS             complement(23433..23960)
                     /locus_tag="IXT22_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4862152.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(23980..24927)
                     /locus_tag="IXT22_000769"
     CDS             complement(23980..24927)
                     /locus_tag="IXT22_000769"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4862153.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(24939..26825)
                     /locus_tag="IXT22_000770"
     CDS             complement(24939..26825)
                     /locus_tag="IXT22_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4862154.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(26985..29063)
                     /locus_tag="IXT22_000771"
     CDS             complement(26985..29063)
                     /locus_tag="IXT22_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4862155.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(29076..29351)
                     /locus_tag="IXT22_000772"
     CDS             complement(29076..29351)
                     /locus_tag="IXT22_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862156.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(29713..30168)
                     /locus_tag="IXT22_000773"
     CDS             complement(29713..30168)
                     /locus_tag="IXT22_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862157.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(30322..31530)
                     /locus_tag="IXT22_000774"
     CDS             complement(30322..31530)
                     /locus_tag="IXT22_000774"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4862158.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(31642..31974)
                     /locus_tag="IXT22_000775"
     CDS             complement(31642..31974)
                     /locus_tag="IXT22_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4862159.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            32122..32997
                     /locus_tag="IXT22_000776"
     CDS             32122..32997
                     /locus_tag="IXT22_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4862160.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(33079..33660)
                     /locus_tag="IXT22_000777"
     CDS             complement(33079..33660)
                     /locus_tag="IXT22_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4862161.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(33666..34925)
                     /locus_tag="IXT22_000778"
     CDS             complement(33666..34925)
                     /locus_tag="IXT22_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4862162.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(34927..35973)
                     /locus_tag="IXT22_000779"
     CDS             complement(34927..35973)
                     /locus_tag="IXT22_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862163.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(36208..36483)
                     /locus_tag="IXT22_000780"
     CDS             complement(36208..36483)
                     /locus_tag="IXT22_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4862164.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(36726..38036)
                     /locus_tag="IXT22_000781"
     CDS             complement(36726..38036)
                     /locus_tag="IXT22_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4862165.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(38218..39447)
                     /gene="rpsA"
                     /locus_tag="IXT22_000782"
     CDS             complement(38218..39447)
                     /gene="rpsA"
                     /locus_tag="IXT22_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4862166.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(39582..40262)
                     /locus_tag="IXT22_000783"
     CDS             complement(39582..40262)
                     /locus_tag="IXT22_000783"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4862167.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(40311..40946)
                     /locus_tag="IXT22_000784"
     CDS             complement(40311..40946)
                     /locus_tag="IXT22_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4862168.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(41012..42415)
                     /locus_tag="IXT22_000785"
     CDS             complement(41012..42415)
                     /locus_tag="IXT22_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4862169.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(42402..43433)
                     /locus_tag="IXT22_000786"
     CDS             complement(42402..43433)
                     /locus_tag="IXT22_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862170.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            43464..43685
                     /locus_tag="IXT22_000787"
     CDS             43464..43685
                     /locus_tag="IXT22_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4862171.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(43850..44587)
                     /locus_tag="IXT22_000788"
     CDS             complement(43850..44587)
                     /locus_tag="IXT22_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4862172.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(44740..46080)
                     /locus_tag="IXT22_000789"
     CDS             complement(44740..46080)
                     /locus_tag="IXT22_000789"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4862173.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(46317..47840)
                     /locus_tag="IXT22_000790"
     CDS             complement(46317..47840)
                     /locus_tag="IXT22_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4862174.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(48218..48829)
                     /locus_tag="IXT22_000791"
     CDS             complement(48218..48829)
                     /locus_tag="IXT22_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4862175.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(48952..49077)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(49159..49875)
                     /locus_tag="IXT22_000792"
     CDS             complement(49159..49875)
                     /locus_tag="IXT22_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4862176.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(49881..50450)
                     /gene="scpB"
                     /locus_tag="IXT22_000793"
     CDS             complement(49881..50450)
                     /gene="scpB"
                     /locus_tag="IXT22_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4862177.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(50434..51231)
                     /locus_tag="IXT22_000794"
     CDS             complement(50434..51231)
                     /locus_tag="IXT22_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4862178.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(51201..51572)
                     /locus_tag="IXT22_000795"
     CDS             complement(51201..51572)
                     /locus_tag="IXT22_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4862179.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(51591..52478)
                     /gene="xerD"
                     /locus_tag="IXT22_000796"
     CDS             complement(51591..52478)
                     /gene="xerD"
                     /locus_tag="IXT22_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4862180.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(52574..53047)
                     /locus_tag="IXT22_000797"
     CDS             complement(52574..53047)
                     /locus_tag="IXT22_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4862181.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(53152..54015)
                     /locus_tag="IXT22_000798"
     CDS             complement(53152..54015)
                     /locus_tag="IXT22_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4862182.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(54211..56310)
                     /locus_tag="IXT22_000799"
     CDS             complement(54211..56310)
                     /locus_tag="IXT22_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4862183.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT        15232 a        12013 c         9645 g        19580 t
ORIGIN      
        1 atacagatgg cgtctcttca ttaaaatact acaacagtta cgactcgatg aaaatctcag
       61 gagcatcgat aacttcgatg acttctccac cttttttctc atccatcgca aatgatccat
      121 tcgatgttcg atcacctata gggaaatcag ttgggtcaat cgttaactgc tgcccttttt
      181 gattcatcaa ggttatttct tttgatcttc cttccgacat atagataata cggtgcggat
      241 tttttttcag ctcacgcatg accgtcactc cccgcttcgc acgtgaagtt tggctgattt
      301 cttgagcaag catgcgttta acagctcctc gctgagtaac gattacgatc ggcgtatcac
      361 cttctgctaa cacaagcagc ccgttgataa tcctatctcc atctttcaaa ttcatagact
      421 tcactccagc tgcctttgct ccaacaacgg gaacatctgt taaaggatag cgcaaaccca
      481 ttccttgatg cgttactaag aaaacatcta agcctggctg atcttctttc agatacacag
      541 caatcagttc atcttcttcc gcctttagct tcatacagct gagcggacgg ctcttatagg
      601 tgcgccatgg ttcgaactct gtcattcgtg tttgcttgat caatccattc ttgctgatga
      661 atacaaatgt tttctctgct tgaatttttt gatatgggaa aacagctaaa atcgattcgt
      721 ctacagacag attggagatt gtttgagaaa tgtgctcacc agcatctttc catttcaaat
      781 cgggtagttc atggacaggg cggtagatca catttgcttt atttgtgatc agaagaacat
      841 ggtccaatgt actcaattca cctgagtata gcaagtagtc gccttctcgc atcccgattt
      901 cttctggttt ggaagcacta taagaacgaa ggcttgttcg cttcacatag ccttctcgcg
      961 tcacactgac aattacgtct tcttgtgcca ctaagacttg cgtatcaatt ttgatttctt
     1021 cgatttcgtc ttcgattgtc gttagacgag cggaagaata attttttttc acttctcgca
     1081 attctttttt cataacagag aaaagctctt tgtcatttga aaggatttta ttcaactctg
     1141 tgatttgcgc aatcaagctt tcggattcct tttgaagctc tgtgatatcc gtgttcgtca
     1201 aacggtataa ttgcaatgtg acaattgctt ctgcttgttc ttctgtaaat tgaaagacgt
     1261 cgactaaatt ctttttggcg tcttttttgt ctttactttc acgaatcgtt gcgattactt
     1321 catccagaat cgataaagct ttcatcaatc cttctacgat atgctgtctt ttttgagctt
     1381 tggctaaatc gaattgacta cgttttgtta tgacttgctt tcgatgctcg atataacttc
     1441 ttaaaatgtc tttcagtcca acttgatgcg gagtcatatg gtcgatagcg accatattga
     1501 aattgtaatt gatctgtagc tcagtgtttt tgaacaaata attcaaaatt ccttgagcat
     1561 tggcgtcttt tttcaattcg acgacaattt gcagacctgt tctatcactt tcatctcgta
     1621 cttcagctat tccatcgatt ttcttattca aacggatctc atccattttt ttcaccaagg
     1681 tcgctttatt tacttcatat gggatttctg tgatcacgat ttgctgttta ttacccttca
     1741 ttgcctctat ctttgttttc gaacgaagaa taacttttcc tcgtcctgtt tcataagctt
     1801 ttttgatttc atcttttcct tgcaagatcc ctcctgttgg aaagtcaggt ccaggaatat
     1861 attccatcaa tttttcaagg ctcgcttgtg gatgatcgat catatagatt gtgccatcga
     1921 tcacttcagc taagttatga gtcgggattt ctgttgcata tccagcagat atacctgtcg
     1981 atccattgac gagaaggttt gggtatcgag ctggaaggac tgttggttct ttttctgtat
     2041 catcaaaatt ccacacgaga tcgactgttt ctttctcgat atctgctagc atctctccac
     2101 ttaacttgga taatctggct tcagtataac gcatcgcagc aggtggatca ccgtccatac
     2161 tcccgttatt cccgtgcatt tcgatcagta cttcccgcaa cttccagtct tggctcatgc
     2221 ggaccatcgc ttcataaata ctgatgtcac catgaggatg ataattcccc atgatatttc
     2281 cgacagattt tgctgattta cggaatcctt tgtcatacgt attgccatct ttgttcatgg
     2341 caaataatat ccggcgttgc actggcttca atccatcacg gatatcaggc agtgcacgtt
     2401 cttggataat atatttggaa taacgtccga agcggtcacc catcacttct tctaaagtta
     2461 attcttgtac ttcttgtcga ttttccatca ggtgacctcc tattctactt caaataactg
     2521 attgttttca tttttatctg ctcgttcttc atctaataaa tcattagaaa ctgaaggaga
     2581 gatttcagta tcctcttttt tatctaagat actgccatct tcttcgagcg taaattgcac
     2641 gtgattttcg atccattttc ttcgaggttc tactttgtca cccatcagtg tggttactcg
     2701 acgttcagct tgcgcagcat catcgatacg gacgcggatc aacgtacggg aagtcggatc
     2761 catcgttgtt tcccacaatt gttccgcatt catctctcca agtcctttat atcgctgcag
     2821 catatatcct ttgccgactt ttttaatcat tgctgccaat tcgtcatctg tccacgcata
     2881 ttcaatgact tgcttctttc cttgtccttt ggatacttta tataaaggcg gtaacgcgat
     2941 atatactttc ccagcttcaa tcagcggttt catataacga taaaagaaag taagcagtaa
     3001 tacttgaata tgggcgccgt ctgtatccgc atcggtcatg atgattactt tgtcgtaatt
     3061 acagtcttcg atagaaaact caggaccgac tcctgcacca atcgtataga tcatcgtatt
     3121 gatttcttca tttttcaaga tatcttgcat tttagctttt tcggtattga tgacttttcc
     3181 tcgtaaaggt agaattgctt ggaactttct gtctcttcct tgtttagcag atccgccagc
     3241 agaatcccct tcgactaaat acaattcatt tttcttaggg tttcgggatt gtgcgggtgt
     3301 caattttcct gaaagaagag attcgccttt tttacgcttc ttcccatttc ggctttcttc
     3361 tctggcttta cgtgctgctt ctctcgcttc tctggctttg attgctttac ggaccaacat
     3421 ctggctcatt tcgctatttt cctgcaaata aaagcccatt tgttcactga tgacgttatc
     3481 tactacggta cgagcaactg gcgtaccaag tttttctttt gtttgccctt caaattgcag
     3541 aagattttca ggtacacgga tagaaagtac agcagctaac ccttctctga aatcactacc
     3601 ttccagattc ttgtcccgtt ctttcagcaa accaactttt ctcgcatatt cattataaga
     3661 tttcgtcatc gccgctttca taccagcttc atgggttccc ccatcttttg tccgaacgtt
     3721 attgacaaaa gataaaacat tttctgaata accgtcattg tattgataag cgacctctac
     3781 ttcgatacct tctttttctc ctgaaaaata aacaactggt gtcaatgtat ctttttcttc
     3841 attcagataa tcaacaaatt ctttgattcc ttcttcgtaa tgaaaaattt ccttgactgg
     3901 ttcttctcca cgaagatcag aaagagagat tttaacgcct tttagaagaa aggcagattc
     3961 tcttaaccgt tcggctaaaa tttcatatga aaatttcgtt gtactgaata ttgtatcatc
     4021 tggtaaaaaa tggacagtcg tcccgtttgc tttttttgtt tttcctatct ttttcaaagt
     4081 accgtcaggt ttaccgccgt ttttaaattt ctgctgatac tctacgccat ctctaacgat
     4141 cgttacaatt agccatttcg ataaggcatt taccacactg gctcctacac cgtgcagtcc
     4201 accagaagtt ttgtaccctc cttgaccaaa ctttccgcca gcatgcagca cagtaaaaat
     4261 cacttcaact gttggtattc cggaagcatg cattcctaca ggcatcccac gtccgctatc
     4321 tgcaacagtt atactattgt cttcatggat ggtcacatca atctcactgc cataacctga
     4381 taatgcttcg tcaactgcat tatcgacgat ttcatagact aaatgatgca agcctcggct
     4441 gtcagtggat ccaatgtaca tccctggtct ttttctaact gcctctaatc cttccaatac
     4501 ttggatggac gagtcattgt attcgttgtt tacttttttt gccaaggcaa acgctccttc
     4561 aataatactt tgcggcaaaa ccgcaccacg attatcatac tagaaaaggt cgtgaaaaaa
     4621 aagagggtag acgagaaatc aattttaatt atctcctaac cgctttttcg acattcccct
     4681 ctatcgatca tctcttcttt gtggtcattt ttatttttgg ttttctttca acttaccaag
     4741 ttcaatctta atacaacgat ccattacgat atctgtacgt cctgcttttc ttagcatctc
     4801 agctgcttct ttgttttcaa tccctaattg tgcccagaac actttagcat cagttttcaa
     4861 aaaatcacct gctatttcag gtaaaaattc actccgtcta aatacatcta cgatatcgat
     4921 tggatcatcg atttctgtca aattcgcata gactttctcg cctagaattt cttcaccagc
     4981 caataatgga tttactggta tgattttata tccattgtct tgcaatacct gtgcaaccat
     5041 gtaacttgtt cgttctggtt tattgctcaa gcctacgacg gcaatatttt ttgcttcttc
     5101 caaatagttg aaaatcgttt cttgtgttgg attttttaca gacatttctg ccaccccttg
     5161 cttttctttt tattccatct attatacttg tatctttcat tttttcaatt gttcctgtta
     5221 cctattcatg ctaaaataaa ggatagtttt caacttgaaa gagggtaaaa aatgaaattg
     5281 atcttattac ttattttagc atatctttta ggttctattc cttccggtgt ctggattggc
     5341 aaattgtttt tcaaaaaaga tatccgacaa cacgggagcg gtaatactgg aacgaccaat
     5401 acatttcgtg tattaggcaa aacagccggg attgttgtcc tgcttatgga tattttaaaa
     5461 ggtacattgg ctacttgttt gccgatgatc ttccaccttt ctgggattaa ccctctttgg
     5521 tttggggtat gcgccattct tggccataca tttccgattt ttgctgggtt caaaggagga
     5581 aaagctgttg cgacaagtgc aggaatgctt ttaggattta atcctgtatt ttttgtttat
     5641 tcttgtatca tctttatcgt tagtttattt tgtacaagta tggtgagttt gagcagtatg
     5701 atcagtgcag tattgatcac tttatctacg atcgtccttc cttatgtagc tcctgtgatt
     5761 ttggctaagc ccaattggtt actgacgatc attgcctttt tagtttcttc ctttatcttt
     5821 tatcggcata aagacaatat caagcgtatc agaaaccata ctgaaagtcg aatcccgttt
     5881 ggtttgaata gcagcaagaa aaaatcctga tactttttca ttccaaagag ataaaacggg
     5941 agtgtgacaa atcgatgtca cactccctta ttacttacag gatagctttt ttacacacct
     6001 tggtaaacgg tgttccctgc taacttctcg gtcacaacct cttacttcac tgtgatggaa
     6061 tattttgtct tgaagatttc atgggcacct agttgattga tccctacttt ttccatcaag
     6121 tttccactac tgttcaccgt gtcagcgatt ccgcaccacg gttcgataca aacgaaaggc
     6181 gcttcttttg gataaggaga ccagatccct acataaggca tatctttata gcttaaagtt
     6241 acgctatggg aagatttttc acttcgaatg gcgtacgcat ttagacccct tgtttcaaaa
     6301 accaaggcat cttgctcaaa aagttcacga ttcaaagcca gattcgtatt tgtctgacct
     6361 aacgtctttt gatccatatc gatgaatggg cctttcaatg gtaggcgtaa tcttgatttc
     6421 aatggagaaa atgccagata gaaatcttca aatgacaatc cttcttcaag aggtacattg
     6481 aaagcaggat gtccaccgat agaaaagaac atttcttttt caccggtatt tgccacttga
     6541 taatgaaccg tgatgccgtc tcctcctaat tcatagctga tcactaattc aaaatcaaat
     6601 ggatactttt ctaatgtctc cggcgtactc cttaagatga aactagccat ttcttgtcca
     6661 tgttcaatga cttcaaaatc catatcccga gcaaatccgt gttgccccat ttgatatgtt
     6721 ttcccttgat aaacatactg atcatctttt aaacgtccaa caaaagggaa taaaaccggt
     6781 gcatgtctgc cccaatacgc tggatcacct tgccagatat actctaaacc atgttctttt
     6841 gatttcagac tgatcaattc cgcaccgtgt tcagcgattt cggcgatcag ctggtcattt
     6901 tgaataataa cagtcattgc cattcctcca acttcgactt actttttaaa atgggaaggc
     6961 tggaacaaac atttctatct gccccagtcc ccttacttct aataactgtg ttttgctaac
     7021 tcgtctttaa aacgggaatt caatactttt aaataagttc ccttcatgcc taacgaacga
     7081 gattcaatga ttccagctga ttccaatttt cgtaaagcat tgacgatcac agaacgagtg
     7141 atgccgatac tatcggcaat attagaagca gtcagacgac cttcatctcc atccaatgct
     7201 tcaaagatag cttgtacagc cttcaattcg ctataagata atgtgttgat tgccatttgg
     7261 acagccgttg cactccgtac atctgcttcg atgcttcgag acttctgata aaggatctgc
     7321 ataccgacaa ccgtagctcc atattctgct aagactagat cgtcatctgc aaacgattgt
     7381 tccatacgag ataagataat cgtacccaaa cgttcgccag ctccaaagat cggaacgaca
     7441 gtcgtcagac caaatggata tttctctctt gactctaccg gaaatgcagt aatatcacta
     7501 gtaattggga tattagcttc agttttcatc aactgtgcca ctgtatcagt ataagattca
     7561 ggaaattgtt tctcaacaaa cattgttttg attcgttcat tgttcacatc gtgacgttca
     7621 ttataaccta gtaatactcc gtcacttcct atgatatagg tgttgctgtc aagaatacca
     7681 cctagtgtga cagccatttt atcgtaaggc aaatctgctt gcatgtcaaa agtattcttt
     7741 tgctgcaaaa gtgtgtttat cttgcgggtt ttcgttagca agtctgtcat tgtcgtcctc
     7801 cgatttttta taaaatatag cgacttaaat cttcatttgc cgcaattgag ccaagtttgt
     7861 catccacata tgcttctgtg atcgttattt ctcccatttg catatctggt gcttcaaata
     7921 atagatcttc tagtagtttt tccaaaatgg tatgcagtct gcgtgcgccg atattatctg
     7981 tgtcacggtt gacatcgaaa gcgatttgag cgatccgttc aattgcttct tttgtaaacg
     8041 taactgacac attttctgta ccgatcaacg cgacgtattg ttttactaaa gcattatttg
     8101 gttcggtcag aatcttcaca aaatcttcag ctgtcaaatc atctaattct acccgtatcg
     8161 ggaagcgtcc ttgaagttct ggaattagat cacttggttt agacaaatgg aaagctcctg
     8221 aagcaatgaa taggacgtga tctgtttgga tgatcccgta ttttgtgttt acttgtgaac
     8281 cttcgacaat tggcaatatg tctctttgga cgccttctct ggatacttct ccagattgct
     8341 gtgatttaga agtgatctta tcgatttcat cgataaaaat aattccactt tcttccgcta
     8401 atttgattgc ctcactatgg atatcagcat ccttgactaa ttttgctgat tcttccttga
     8461 tcaataactc taaagcttct ttgactgtta ccgtccgttc cacttttttc ttcggtgtca
     8521 aagcacctag agtttcattt aggtcgatcc ccatttgctc caatccattg ttcatcattg
     8581 gtgcaggttt cttttggtct tcaacttcaa tggttacttc acgactatcc agtaaaccct
     8641 tttgtagttg ttccaagact gtacggcgat tgattcgaat atcttctgtc acttcttctt
     8701 gcggttcagc ggtattttgc tgactagcat taaaaagatt catcatttgt tcaaattgat
     8761 tagtggattg tttctgttct tttttgatac caggtaccaa gatttttacc aaacgttttt
     8821 ctgcattttt tttagcactt gtgtatacac ggctgtactg ctctttttct acgatttgga
     8881 tcgcattttc tactaaatcc cgaaccattg attctacatc tcttccgaca taaccgactt
     8941 cagtaaattt tgttgcttcg actttgacaa atggtgcatt gacgattttt gccaaacgtc
     9001 gtgcgatttc tgttttaccg acccctgtag gtccgatcat cagcatattt tttggtgtaa
     9061 tatcttgttg cattttttca tctaactgca aacggcgata gcggttacgc aaagcaacgg
     9121 caacagattt ttttgctgcg tgctgtccta cgatatattc atctaattca cttacgattt
     9181 gtcttggtgt ttgttttaat tcatacatat ctactcacct cttacagttc ttctacgata
     9241 atattatgat tagtaaagat acagatatct gcggcaatat ttaacgcatt ttctgcaatt
     9301 tctttcgcac tcatgtcgtt ttgagcatag tttttcattg ctcgggctgc agccaacgca
     9361 aaattccctc ctgatccgat agctaagata ccatcatctg gtgtgataac ttctcctgta
     9421 cctgaaacaa gaagcatttc tttatcattc attacgatca gcatcgcttc aagtttttgc
     9481 atagattgct gtgtccgcca ttcttgagct aattcgacag ctgcgcgttg tagattcccg
     9541 ttatattcgt ttagtttgcc ttcaaatttt tcttctaaag taaacgcatc tgcaacactt
     9601 ccggcgaaac ctacaacaac ttctccattg tagatacgtc gtactttctt tgcagtgcct
     9661 ttcatgacaa cagattcacc cattgttact tggccatctc cagccatagc aaatttcccg
     9721 tctttttcga cggcacagat agtggttgaa tgaaatggtg attcgaccat gtttgtttcc
     9781 tcctaaattt gttcttttcc ttatttttac gctcttggat ggaaagaacg atagtttttt
     9841 tgtaaacttt cttttgttac atgggcatag atctgggtag tcgataaatt ggcatgtcct
     9901 agcaattctt ggactgtccg caaatctgcc ccattattta ataaatgagt agcaaatgta
     9961 tggcgcagca tgtgaggatg gatatcacta tccaaactgc tttttttgat catttgattc
    10021 aagacatatt caattccagt aggcgtgatt ggttttccat gatgattcac aaaaacgata
    10081 tcatgctctt cgtgatattt tgtcatcaat acctggcggc cttccctgaa atattcttgc
    10141 agagcatctt gagcaaaaga acctagagga gcatatctct ctttgttccc tttaccatgg
    10201 atcaacatga cctctgaatc aaaatcaatg tctgataccg acaaactgct acactcactt
    10261 aaacggatgc ctgacccgta aaggacttcc agtaaagcgc ggttcctcaa atccaaagga
    10321 ctatctcctg ctacgctgtc aaaaagtgct tgcatttcat tttcataaaa aaaacgtggc
    10381 agtctcaaat ttttcttttt gagatgaacg taagaaaatg gattttcttt tatcacttct
    10441 tctttgagaa gatactgata aaacgaacgt aggctggcta tcttgcgact gatagaattt
    10501 ctgctatagc taggacgatg atcagctaat gcactcaaat agacacgaac cgtaaaatat
    10561 tccgccttca gcagatcagc gtctccagat tcctccaaaa aatgtttgaa atggagaatg
    10621 tcttcttcat atgcttcttt cgttttttct gaatatcctc tttcgacaat caaataacgc
    10681 aaaaattttt gttcccacgt ggcttctgtc attttctcac cttccttttg tcccagagaa
    10741 taatttagca cagcgtttat aaaaagacaa ataaattgtc agaatttaac caatatttct
    10801 aagtttgttc acaattggcg caattcctca cattttgttt gagaaattct taagaaaaac
    10861 gcaagaaaaa gagcgagact atccgtctca ccctcttcat ggagtttcct tactcatttg
    10921 ggattgcagt tttttctaat tctgttttta ttgcctcatt agcttttaaa gctcgttgtg
    10981 caattgcttc atatcttgct tttttgtctc gaatgcgctc tggcagttca ggaaacagac
    11041 catagttggc attcatcggt tggaaatgtt ttccttccgc atgagtaatg tagtaagcca
    11101 tacttccaat agctgtttct tgtggaaact cgactggttc catttctttt gctaagcgtg
    11161 cggcgttgat tccagcaagt agtccgctcg ctgcactttc aacatagcct tctacaccag
    11221 tcatctgacc tgcaaagaac agatcttcgc gtttcgttga ttggtaagtc ggtttcagca
    11281 attctggcga attcataaag ctgtttcggt gcatcacacc atagcgaacg aattcagcat
    11341 tttctaaccc aggaatcatc cggaaaacac gtttttgctc gccccatttc aagtgagtct
    11401 gaaagcccac gatgttgtat aaagaagctg cagcattgtc ttgacgcagc tggataacag
    11461 cataaggacg tttgccagtt ttaggatctt ccaatccaac tggtttcata ggtccgaaaa
    11521 gcatcgtttt gaatcctcgc tgtgccatta cttcaattgg catacatcct tcaaaatatt
    11581 tttctttctc aaaagattta agttctgcca cttcggcatt gattagtgcc tcatggaaag
    11641 ctttgaattc ctcttctgtc atcggacagt tcaagtaagc tgcttctcct ttgtcatagc
    11701 gggacttcaa atatacttta tccatatcga tcgtagcttt gtctacgatt ggtgcagctg
    11761 catcatagaa ataaaaacca tctgaaccat tgaatgcttt gatgctttct gctaatggat
    11821 gagaagtcaa aggtcctgtt gctactacgg tgattccttc cggtatttca gtaatttctt
    11881 cgtttatcac tgttactaat ggatgctctt tgacttttcg ggtaattgtt tcagaaaaag
    11941 aatcgcggtc aacagctaag gcaccaccag ctggcactgc tgtttcatct gccgaagtga
    12001 ttactaccga attcaatcgg cgcatttctt ctttcaataa ccctactgca ttagccaaac
    12061 tgtttcctct taatgaattg gaacatacta gttcagcaaa attacttgtg tgatgcgcct
    12121 cagtcgattt gactggacgc atttcatata aacggacagg gactcctgct tgtgcgatct
    12181 gccaagcagc ttcacttccg gcaagccctg ctccaacaac atttaccatt ttcaatgaaa
    12241 gaacctcttt tctattattt ttggatgtct tcttcgtaat ctccatttac acagactact
    12301 tgtttaccgc ctttgacttt cttctcgacc agatatccgt cacattttgg acaatttctg
    12361 cccactggtt tatcccaaga agtgaattca cattctggga aacgggaaca accatagaat
    12421 agtctgtttt tcttagattt tcgttcaatg acttgtcctt catgacatac tgggcaagtc
    12481 acaccgattt cttttacgat tggtttcgta ttccgacaat caggaaaatt actgcaagca
    12541 taaaacttcc catatttccc taattttatc accatcggat gtccacagac atcacaatcg
    12601 aatcctgctg gttcatcttt gatttgaatt ttttcgattt tttcttccgc attcgtcagt
    12661 tctttttcaa acggtttata gaaacgatca accactttga cccacgcttc cgtgccttct
    12721 tcaattttat ccaaatctcc ttccatttct gctgtgaaat ggatatcgac gatttgaggg
    12781 aagaattcac agattaatga attgacaatt tctcctagtt cagtcggctc aaatcttttt
    12841 tgtgtcaatt ttacatagta gcgtctttgg atcgtatcaa gtgttggtgc ataagtggaa
    12901 ggtcgcccta ccccgttttc ttctagtgca cgaatcaacg tagcctcact aaaacgtgct
    12961 ggtggttgag taaaatgttg ttttggttca atatcaacag attggactac atcgccttct
    13021 tcaagttctg gaagaatatt ttctttctct tctttgccgt catctctacc ttccacatac
    13081 acttgcatga atcctttgaa tttgattttt gaaccgttcg caatgaagat gacaccattt
    13141 tgttctaatg tcactttcat tgtatctaaa atagctggtg tcatctgact agccacaaaa
    13201 cgtgaccaga tcaatgtata aagtttcaat tgatctttat ctaaatattg tttgagttca
    13261 tctggtgtac gaagcacact cgttggacgc acagcttcat gggcatcttg tgcgccttga
    13321 gcatttttga tctttcggtg atcatgtcta gaaaattctt ttccatacgt atcttcaata
    13381 aatgctgcgg cctctgcttt tgctgtatcg gcaatccggg tagaatcagt acgcatgtat
    13441 gtaatcaagc cgactgttcc ttgtttaccc aaagtgattc cttcatataa ttgctgtgct
    13501 accatcatgg tttttcttgt tcgaaagttt aacttacggg cagcttcttg ttgcaggcta
    13561 cttgtagtga aaggattcgc agggtttctt ttgcgctctt tcttttctac ttttttaact
    13621 tcgaagtctg ttccatcaat tctagcagtg acttctttta cactttgtgc atctggtaat
    13681 ttctttttct taccgtcgat tccccagaaa tttgctttga atttcttgcg agctttttta
    13741 aaattaccgt cgatgctcca atattcttct ggaacaaatt ctcggatctc tttttcacgg
    13801 tcaataataa tttttaaagc gacagattgg acacgtcctg cacttaaccc tttcttgacc
    13861 ttacgccaga gaataggact gatcgaataa ccaacgattc tgtctaaggt acgacgagct
    13921 tgctgtgcat ctactaaatc tacatcgatc gttcttggtt ccttaaaagc tgctttgact
    13981 gcgtcttttg tgatttcatt gaagaccacc cgattttttt ctttcagatc caacccaagt
    14041 aggtacgcta aatgccaagc aatcgcttct ccttctctat ccgggtcact tgccaagtaa
    14101 actttttgag ctttttttgc tgcggctttc aggcttttga tgacatcgcc ttttccgcgt
    14161 atagaaatat aatggggttc ataattgttt tcaaaatcga tacccatttt acttttcggt
    14221 aaatctctta tatggccaac actggccatt actttatagt ttcgtccaag atatttctca
    14281 attgtcttgg cttttgcagg tgattctaca atcactaaat atttatacgc cattactgaa
    14341 tggactcctt tccattgtcg tgttcctact attaaaagag gattcataca aatcgtagct
    14401 aatcatatcc attcagaaaa cgtttgtcaa gaaaagcaaa tgaaaagtat ggtgttattc
    14461 tttaaattct gccaagatat cttcacccga aaccgtgcaa actgcaccgt cttggatcaa
    14521 atgatgacat ccggtagaat gttctgttaa aatatttcct ggaacagaaa aaactgttct
    14581 tccaagatcc aatgcttgct gtgctgttat cagagagccg ctttttttct tggcttcaaa
    14641 gacacatgtt cctttagaca aagctgcgat aatccgattt ctcattggaa aacaatgctt
    14701 tttcgggccg gattgaggag gatattcact caaaagaaga tgatcatttg caatcacctc
    14761 ttgcaagtca cgattttcag caggatagac ttgctctatc cctgttccaa tgactgcgat
    14821 tgtccgtcca ccatgagaga ttgctgcttg gtgaccgtat gtatctatcc ctttcgcgca
    14881 gccactgacg atcacatatc cagcttctat cactggtttt agtaaataat aaactgtttt
    14941 tttggctaaa gcagaagtgt gtcttccacc aacaacgctt aacatgttac aagaaagtaa
    15001 agatagatca ccattataaa acagtacaat tggcggatag gtcaagtgaa gcagctgagg
    15061 gggatatttg ggatcaaagc aagtgataaa cgactgtttc gattggattt tgccccagtt
    15121 agcgtgaatt tcctgccaac ttttgcgaaa cagctcccgg tgtttggtta ttttacctat
    15181 cttaatgatg tcttcaaatc cgatttcttt ataaggatac tgcatcatcc agttagcaag
    15241 tgcccatttt ccttgactac tgattccttt tgtataagca agtttcaata aattttcttc
    15301 tatttgatac atcataaaac cgcctttcgt ctctctttct aataagatac gtaaaagcgg
    15361 ctgtttttta ttgtaaatat ttttttacag gtgcaaaact tttacgatgg attggcgtaa
    15421 ttccttgtcg ttcaagtcct tctaagtgtt cctttgttcc ataacctgca ttatgcgaga
    15481 aaccatatcc aggataaagc acgtcatatt ctttcatcaa ttggtctcga tatactttag
    15541 caatgatact tgcagcagca atcgacacag atcgtacatc ccctttgatt attttttcct
    15601 gctgaatagg caaatccaag gtcatcgcat cgatcaacaa atagcttggt acaatggaca
    15661 atttttctac tgcttggatc atcgctaatt tacttgcttc ataaatattc acatcatcga
    15721 ttgtctgctg atcaacgatc ccgatcccga ttgccagggc tttttcttga acttgttgat
    15781 aaagaagttc tcgctttttc tctgataatt gtttggagtc attcagccct aatatgatct
    15841 catttttcgg caagataact gcagctgcca cgacaggtcc agctaatggt cctcttccta
    15901 cttcatcaat gccggcaatc cattggtgac cttgtgcgta cccttgcttt tcaaagcaaa
    15961 acatttcttc atatttttcc ttaattaatg cttccttttt caatcgtcgt tcaaaagaag
    16021 ccagtgcttg ctgcacgcct ttgcgtggat catttcttaa tgattctagt gtaggatcat
    16081 ctattctctg tatgcttttc aatcgttctt tgatactttg gatggattca gtcatcactt
    16141 ttttgctcca tttcttcgca acgatccagt gtgtatcgtc caagttttcc ttgacgaata
    16201 tcatgcacga ctaattcgct gccacgatca tagtcttctt tatacccacg ttttgctgta
    16261 atatccatca gtaattccgg tgccaatttt tcttcttgct cgattgataa accataacga
    16321 tcgctgattc ttcctgaata atatcgggca aaaaagtcta atccgtaaat cgctaaatca
    16381 tctaaatgga caagctggtc tttgatcgcg cctgtcagcg ctagtttttt gccgatttct
    16441 tcatcttcaa atttgggcca taaaatccct ggtgtgtcta acaattccaa ctcattacct
    16501 aaacgaagcc actgctgacc ttttgttacg ccaggcttat ttcctgtctg tgcaattttc
    16561 ttgcctacta gtcgattcat caacgtagat ttcccaacat ttggaatacc taagaccatt
    16621 gcccgaatag cgcgaggctt gatcccccga gcagcatctc ttgcccgttt ttctttcaat
    16681 gcttctttag ccgcaggtac tagaccttta attcctttac tttcttgtgc cgtgatagct
    16741 aatgcaagat ggccttgttt acgaaaatat tcttgccaca gctttgtctg ttgtggatct
    16801 gccagatccg ctttattcaa taaaacaagg cgaggttttt gctgaatgat ctgatctagc
    16861 attggattac gagaagataa aggtaatcgt gcgtctacca attcaaatac gatgtccaca
    16921 tatttcattt tttcagaaac ttctcgtcgg gcttttgcca tatgtcccgg aaaccattgg
    16981 atggtcattg ttctctccat tcctttcata ccggaatatt ccccggcttt acttgttttt
    17041 ttctttttca atataaattc acttttttat tataaagaaa ttccatctat tagttaagtg
    17101 aaagtgaacc agtcctcatt ctatcacatc ttcacttttt tgatgatgca aatttttatt
    17161 ttggtttcta tatatgaatc taaatttttg acagcgtttc ctaaataaga gatgatagac
    17221 gaacaaaaca gaaaggagac gaaacaaatg aatagtatgg tttttgttaa ttttcctgtt
    17281 gctgatgtca atcgttccgt tgctttttat gaaaagctgg gttttaaaaa aaatgaagaa
    17341 ttttctactg aagaagctgg ttcaatggta tgggatgaca ctttttggat aatgcttctc
    17401 tctcatgatt tttataaaaa atttataaaa gataaagaaa tagctgataa taaaaaaaca
    17461 agtggtgctt tgatttcgtt tagtgttgaa aatgcggatg aagtaaaaaa atttgctcaa
    17521 attgcaaaag aaaatggtgg tactttccac gaagtagata tgggaatgcc tgaagaagaa
    17581 atgttttcat tagaagtcca agatctagac ggaaatacat tagaacccgt atggatgaag
    17641 atgtaagcag ataactaatc tgacgttttt tataacaaaa aaacaaaggc ggatgatacg
    17701 ataagtattc tccgcctcta ttttttttat tcgtacaatc tcttttttac agtttataaa
    17761 agcagtcttc tcaccctttt tttaattgtt agatgccagt gtatgtaaat caccaatgtg
    17821 tcatgacaca ttggtgattt tatggtatcc ttttattatt aactgacaaa ggagagaata
    17881 ttttgaacac tttgattgca aaagacgttt ttagattgcc cgaaatgaat gcaagattgt
    17941 tgtcgacctc tgctctttta ttagcccttg atgtcatctt atacaagata gcgattggtc
    18001 ctgcttattt tcaaatcaca ttcggatttt taagtatggc gcttatgggt tatctatatg
    18061 gaccgatctg ggctggtttg cttgaaatgt tgtcgaacac tttaaatttc acgatatttg
    18121 gttcaggaac gtttcaagct gcttttctta tcacggcttt ccttggtgga tttattaatg
    18181 gcttattttt atatcataaa aagataaacc tgccttccgt catcgctgcc caattattga
    18241 ttatgatccc agtcagcctt tttatcaatt cttggctgat gtctgttttg tttggtgcag
    18301 atttcaaagt aatttttcta ggtagattca tcaggaatat gatccaaatc cctattcaaa
    18361 taatggttgt ttattcattt atcaaaactt tagaggctag aaaagtgttt aaacgagctg
    18421 tttgatttta cgtactaagg tagtaaactg attttggatt aaacaataaa gcgtgcagtc
    18481 tcaacagact gcacgcttta ttgtttctca ctggatccat tttatttcat caagtggata
    18541 atagacaaat cttgctttac ctagaatatc agttttattg atcgtgccaa acgaacgact
    18601 atcttttgaa actcttcgat tatctccaag tacaaaataa ttatcttccg gaagcttgga
    18661 ttgtcccgtt agctcttgta gtgtaaagtc cgtcgtatag gatgcatttg catgatctga
    18721 tttcaggttt ttagttagat aaggttcctt aactactttc ccattgatct tcaattgatc
    18781 attttggtag ctgacatttt ctcctggaag accgattact cgtttgatat aaatcgtgcc
    18841 atctgctaat tgaaaaacaa caatatcaaa tcgtctgatc tccgaaaatt tttccatcac
    18901 aaccatatca ccttgcttca acacgttttc cattgaattg ccttccactg gtaccgggat
    18961 gaataaaaat ccccgcaaca tgaacgcaag gaatacagaa acaagtaagt atttgaatac
    19021 aagccagaag cgattaatat agcgttgttt ttttgtcaat ctctatcaat ccatccctct
    19081 ttttttcatt ctttctttat tataagaaaa atatcaaaaa aatgcgacta gatagctgaa
    19141 ataaaaataa ttctttcaat taggctattg gacaaaaaac ttttttgatc ataaagtaca
    19201 aaactatctc ttatatgtca tgattatttt ctaaatattt ttcccatgct tcgtcaaaga
    19261 tatccatgga cggcaaatag tcgacattca gttccagata attagaaatt tcttcgtagc
    19321 tagagctgtg cttaggaaat tggatgtctt taccggcttc tgtagcgaaa acagataaag
    19381 catcatgtgt gccaccgcct cgcagtgtca ttaaataatg aaaaaagctt cgattcaccc
    19441 ttcgttcctc caattttctt cgataaaggc agcccggcgt gcatggtttc ttttaaaatt
    19501 ttcaggatgc tttttataat actcttgatg gtcttcttct gctagataaa atggttgggc
    19561 tggttcgatt tttgtaacga ttggctgttc gaaacgtcca ctttcagcta actgtttctt
    19621 acttttttca gcaatgatcc gctgttcttc tgtcaaataa aagatcaccg ggcgataatt
    19681 gtcaccgcga tcctcgaatt gtccgaaagc gtcagttgga tcagtttgct gccagtaaag
    19741 ttctactaat tgttcatatg aaatcaatgt tggatcatag ataatctcca ctgcttctgt
    19801 atgtccagtc gtttggcttt ttacttgttc ataagtcgga tctggtacat gccctccagt
    19861 atatcctgac atcactgtat ggataccagg aagcgtgtcg aaaggctgga tcatacacca
    19921 gaagcagcct cctgcaaata ttgctcgttc cattatgatt ccccctctaa tactactcat
    19981 ccgatgattt tttattttct tttgtcttgc tttcagtact gctggtgcta gttttgttgg
    20041 tatttgagtt gtttgaagca tcagaggtat cttttggcaa atatagacta aaccgaatgt
    20101 catcatttac taagtcgatt ttatctgctt taatatacat cccgttttgc attcggaatt
    20161 gatccaacct aagcatgata gtcagatcat ctgtattgac ttcgatccaa tctggtaatt
    20221 tatagtttct cttgatcata ttcatcacat ctttgattgg caaactcaat gttccgatag
    20281 aaagacttct agcttttagt tggacatttc cgttttccat cacatacgga tcaaaatata
    20341 aatagaaatc gataggaaaa cctagtactt cgaaagtacc attgagtagt gcttcatttt
    20401 ccaaataaaa tttatattca atatcactat ctttttgata ctcactaagg aaaaagctga
    20461 tgatttgatt gactttttct ttatttgaat tgatcgttaa gacaggatct ccttgtcttt
    20521 ccgtaagagc tggtatttct gggagttctg gttcccgatt agcaaaaata cggctgccta
    20581 aaaatacggt cgaaccaagt actaccccaa gaaggataag gaaggcgaat ttccagtaat
    20641 ttgttttctt tgttttgttt gaagatacgt cagatcttgt tttcatgttt attgatcatc
    20701 ctccttctct aaccattggt tttgtgtctc gatcagctga tctctcactg catttgccat
    20761 caattgataa cctaaattat ttggatggaa atgatcttct tcatagagca cattattttt
    20821 gatgccattt agattttctg tcgtgctagt tgtttgatct gttccttctt ctgtgacacc
    20881 tacttcctga ttcaatcctt gataaagcaa atcattgatt gggataaagt agcagttcgg
    20941 catttttttt gtcaccgttt ctgttccttt gttccaattg ttaacaattg tctgcatgtc
    21001 agtgatctca ggaaagttca aataaaatgg attgtagatg cctaaaatgt aaataggtgc
    21061 ggttttattg agggatcgaa attcttccaa tagttctgtg acattttcct gatagttttt
    21121 cagtggcttt ttaaaggaat tgaccgttaa cccgaataaa ttattttgga taactttcat
    21181 caaatcatta ccgccaacag tcagtgtgat aaaatcagct gttttgatat tgtttcgaat
    21241 ttcttctttt gtttttactc gctttaagat ctggtcactt cgttcaccat ttacaccata
    21301 gttttctgtt tcaaccgcgg tcaaattata acggtctttt agatcatttg cgacaagggg
    21361 aacgaatcct ccttgcttgg tttgatctcc tactccttca gtcagcgaat ctccgatagc
    21421 tatgtagtga agtttttctt ttttatttgg atcttctctc acagtagtta ctggtttcat
    21481 tagtgggcca gctttcggta tagaagcagc taaacctgca tagatgatga tcgcaattaa
    21541 taatgggaac aaaacgagga tcaaatgtcg tttcgttaat ttcatttttt cacctcttgt
    21601 attcgattgg ttctaatgtt atcaaaaatt ttatcaaaaa ggtagtcttt atgaaaaaag
    21661 aaaacaatta ttttcctaat tttataaaga aaaagagaat aagctgcaag cctttcaggc
    21721 tgagggctta tcctcttttc gactaatcta cataatacat gattgcaaac gcgtctttac
    21781 cagtatgcgt agcgataacc ggattcgtat gcagtacagg gatatgcatg tccgggaata
    21841 attcttgcaa accctctttg aattcttgcg ccaattcttt tgcatccgca tgtgaaatac
    21901 cgatttgtcg cacatttggc aattctttca gttcattttt caaattatta aaccatttat
    21961 cgaacgtttt ctttcctcgc cccttagtta cagggattaa ttcagaatgg gcgaaattca
    22021 tcaccacgcg tatgttcaaa acactagaca gcaaaccagt tgttcggctg attcttccac
    22081 cttttaccaa gttatctagt gtggatattc cgatgtataa ttttgtattg tcttgtactt
    22141 ttttgacttc ttcaaggatt ttctctactg ttttaccttc ttttgctaat tcagctgctc
    22201 gaattacctg aaaagataat ccttggtcag tggtatcact gtcgataacc gttactttcg
    22261 tttttgttag attactggct tgtcttgctg cttctactgt tccactcaag ccttttgtca
    22321 tatggatcga aatcacttca ctgccgtctt ctcctagctc atcatacatc gagatgaatt
    22381 ctccaattgg tggttggctt gttttgggca gattttttgc tttcgccatc atttccataa
    22441 atctttcgcc gtctagttgg tcatcatcgg gatatactgt tccgtcgatc atgatggata
    22501 gcggcatgac acgaatgcct aaagcatcgc gtacattttt ttccatcgta catgaagaat
    22561 ctgttacgat ttttacattt gtcattattt tctctctctc tttctttaac aagatgcctt
    22621 attcatgtta aactacatgt aagacaattt ctatttttag tataacagac aaataatgat
    22681 ttttcattaa ttacacctag taaaggagcc gttttcatgg aaaaaacgaa atttaatcga
    22741 acgtatgaaa tattaaatga agtgtttaat gcagtcaccc atggaattgg gactggattg
    22801 agtatcgcgg gactagtggt tcttttagta aaaggtgccc acttgcattc ctccctccat
    22861 attgtctctt atgctatcta tggatcgatg atgattcttt tatttttaac gtctactttg
    22921 tttcattcat tgatttttac aaaagcaaaa aaggtgttcc aagtattcga tcatagttcg
    22981 atttttcttt tgattgcagg aagttatact cctttttgtt tgctgagtat ccgaggatgg
    23041 ctaggttgga ctttatttgt attaatctgg ttgtttgcga ttcttggcat tatatataaa
    23101 gcgttgacgt tgcataaacg ggagagagta tcaaaagtat ctacgatcat ctatattttt
    23161 atggggtggc tctgtgtcgt ggctgctgtt cctctttatc actctcttgg aatgactggt
    23221 gttattttga tggtagcagg cgggctttct tacacgatag gcgcattctt ttatagcttg
    23281 aattctatcc gctatatgca tgttgtttgg catttgtttg ttatgttagg tgcaggtttt
    23341 atgtacttct ctgttttatt ctttacttaa taaaaaaaat aaagctatgg atgggacagc
    23401 tctaaataac agctagtcta tccatagctt ttttatatcg tcaattcgcc tgtcccgctt
    23461 tttacaggat tctcattacg ctgatacgtt tcaaattgat gcggataacg atttttttca
    23521 tccatttctc cttgactagt attgatcagt gaccaatcag accagtcaac aggtggaaaa
    23581 taagcatctc catcgaatac atgatggatg actgtacggt ataatatcgt acaaaatggc
    23641 agaaattctt gataaacagc tgaccctcca gcgatgaaaa agataccgtc tgtttctttt
    23701 tccagagcaa gcacgtcttc cacactatgc atgacatgca cgccttctgc tttataggaa
    23761 gaatctctcg tcaaaacaat cgtctgacga ttcggcaacg gacggctacc catcccttcg
    23821 aatgtttttc gtcccatcac tagtgtattt gcttctgtca tttgtttgaa gaatttcaga
    23881 tcatttggca aacgccaagg aagacggtct tcttttccaa tcaatccgtt ttcatcctgt
    23941 gcccaaattg cagctaacat tttctcatcc tttctgattc taaacagcga taggagcttt
    24001 gatcgccgga tgtgggtcat atccttctaa ttggatatct tccatctcaa aatcaaatac
    24061 tgactgcttt tcctgattca aaactaaagt cggaaatgcg cgtatttctc ggctcaattg
    24121 ttctttcatt tgttcgatat gattgatata aagatgagca tctcctaatg tgtgaacaaa
    24181 ttcgccaacc gctaaacctg tttcatgtgc aattaggtga gtcagcaacg cataacttgc
    24241 aatgttgaac ggaacgccta gaaacacatc cccactgcgt tgatacaatt ggcagcttag
    24301 ccgtccctct tgaacataaa attgaaacat cgtatgacaa ggaggcaaag ccatgctagg
    24361 aacatcttcc ggattccatg cagaaacgat caatcttcta gaatcaggag tctttttgat
    24421 tgcttcgatc acttgtttga tttgatcgat aaagccaccg tcttttgttt cccagtgacg
    24481 ccattgatag ccgtagatgt gtccaagatc gccgtatgtt tcagcaaagg aatcatcggt
    24541 taggatcttc tcgcaaaaaa gcttgctctg ctttttatat tcttcattga attcaggatc
    24601 tgtcaaacat ctatggccaa aatcagtcat atctggtcca ttatagtctg gacttttgat
    24661 gtagcgttca aatgcccatt catcccaaat atggttttta ttttgtaata gatagcggat
    24721 attcgtatct ccttttaaaa accaaagcaa ttcgcttttg atcaatccaa aaggtactcg
    24781 tttcgttgtt aacaaaggaa accctttttg cagatcaaac cgcatttggt atccgaataa
    24841 gcttaatgtg cctgtgcctg ttctgtcttc tttacgatgc ccttcttcca acaattttct
    24901 tcctaagtca agatacgctt gttccatcct ttttcctcct aatcttctac ccattcactc
    24961 aagtattccc accgtgccat tttttcttca agttgtgctt ctgtttcaga tacgtcgttt
    25021 tgcaattctt gtaatcgagt gaaattatct ccttgatgat tcatctcttc ttggagcaat
    25081 gagatttttt cttcaagttc tgcaatctca tcttcaatcg tttcccattc tttttgttcc
    25141 atgtaagata atttcttctt ttcagcaggt tccttgctct gtatttttgg tttcgctttt
    25201 tcagcaggct gctgggtctc tttttgcttc agtaaataac tggacatgtt tccgtaataa
    25261 agttcttgtt ttccgtttcc ttggaatact aataacttat ctgctacctt gtccaagaaa
    25321 taacggtcat gggaaacagt gatcacagca cctggaaaac ttctaaaata atcttccaaa
    25381 atcgtcaatg ttgctatgtc caaatcattg gtcggttcat ccaataataa aacattaggt
    25441 tgctgaatca gcagtttcaa caaaaataac cggcgttttt ctccgcctga aagtttgcct
    25501 atcagtgtcc catgcataaa tcttggaaat aaaaatcgtt caagtaattc tgctactccg
    25561 atttgactgc catctgctgt ttttgcttct tcagcagctt cttgtaagta agcaatcatc
    25621 cgtttatctg gtgccatttc ttcattttct tgtgtataat acgcaagatg aaccgtttca
    25681 ccgatagaca ttgtaccgct atccagggga attctgccag ctagaatatt aagcaatgtc
    25741 gattttcccg caccattttt accagtaata cctagtcttt cccgagattg aatcaataaa
    25801 tctaaatgtt ctagcagtgt ttggtcattt atacggtaac tgccatcttt gatttccagt
    25861 acttttttcc ctaaacgttg tgtcgctagg ttcagctcta aatcatcttc ttggtttact
    25921 tggtacaagt tctcctttag atcttcgaaa cggttgatcc gtgcttgctg cttggtgcca
    25981 cgtgcctgta cgccagccct catccaagct aattcctgtt tataaagccg cttgcgcttt
    26041 tcttcttgtt ctacttctac acgatcacgt tctgcttttt ctaagacgta agcttcataa
    26101 tttcctttat actcgtataa ttttccaaat gaaagttcga agattcggtt tgctactcta
    26161 tctagaaaat aacgatcgtg ggtaaccatc aatagtgcgc cacggtattg tttcaaatag
    26221 ttttccaacc actcgatcgc ttcataatct aaatggtttg ttggttcgtc tagtaatagt
    26281 aaatcgggtt catcaatcaa cacttgcgcc agactaactc gttttttctg accacctgat
    26341 aaagtactga tttttttatc taattcactg attcctaatt tttgcaaaat aatctttgcg
    26401 ttggtatctg tagtccaagc atcttcttta ttcatttgtt cttctgcttt agcataacgt
    26461 ttttgcacat cagggtcttc tccgttttcc cctagttcga tcaatgcttc ctcatatgct
    26521 cgaacagttt ggatcaaggg gctgtttcct tgaaagactg cttggagaac agttaattca
    26581 tcggaaaatt cagctgcttg agaaagataa ccaatacggt aatcagttgg ataaaacact
    26641 gtttgccgat caccgtcgct gctatcgata ccggcaataa tatttaagag acttgtttta
    26701 cccgtcccgt tcgtcccaat caacccgata cggtcttttt cgtggaccaa aaaagaaatc
    26761 tggtcaaaca aatctttttc accataagtt tttttgaggt cagttacttt taattctttc
    26821 aacatgttcc ctccttatct tggatattgt atcataaaaa tagtgaactt caggaaaatt
    26881 tttttggtat ttgttctttt tgtgttctca aaaaaagaac aggaccgatt cgatcctgtt
    26941 ctgatatgtt ttgtttttta taaaacttga aaatttttac ctttttattt tattggactc
    27001 gttttttttg actttgctcg aaacgcaaat cggaaagaaa agttatcaga tggtttgttc
    27061 atcgtataag attctaacaa attgatattc ctgcgatagc tgttcgcaga aaacgtcgtg
    27121 attttttcag caacttcgta ttcatcaatg atttttcttt caagataata acctcttagc
    27181 atttttttcg taaacagact atcttgctgg atcatccacg aagaaatcaa attccccgag
    27241 ttcattttta ttccttcaag tttgcgttgc tggataaaaa attgaaccat cgtttcatca
    27301 taaatatcag tcaagttatc taaactttca ataatcaact gagtattttt ttgatatgtc
    27361 tctctgattt cttggatatc ttcatcacta ataaatgtct gacgatcagc atatcttctt
    27421 tgccaaaaca ttttcggatg gagaacgatt cgcattaacc tacggacaac aatgaaccaa
    27481 aagccgataa aagacaaaat ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg
    27541 gagtaaaaac gataaccatt agaagaaagc ttgcccgaac gataactttc atccaatcca
    27601 tcccgttcga tcgacaaaat cagtgcttgt atttcttgta cttcttgctt ttcatcatcg
    27661 gttaaatctt ccaagtacag atcacgtatc cgttcttgat aattttctat cactgcttca
    27721 gtggctaaaa attcttttgt attacgatca atttccttta tttcttttcg caaaacttca
    27781 acgacctctt ctaaaatcat caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc
    27841 gtcagcatag gcaagacaat gatccctatg accaaagtca ctaagatgac acccgccgtc
    27901 agaaacaaaa gcaaagaccg ctggtaaaac atcatattat tgattgaaaa tggcaaaata
    27961 aaaatcgtag ccaaactgac tgttcccttt acaccgccaa atgttaagat caagatctcg
    28021 ttcaactgtt ttttgaactt tttactgcca tctttgaata cataaaaaag actgatagaa
    28081 atgaatctga tcacaaaaag catgacagag attaatacga taatcgctaa taaaagaccg
    28141 tttggatata aaccgtctcc ccatactggc gagaacactt gcgtcaattc gattcctaaa
    28201 aatataaata ctaatgcatt cagtgtaaaa gcaatagttg tccatgtact gtgggacaag
    28261 ctcgacaatt ctgcatcaaa cacagagatt ttcctaaaac cagaagcttg gagaatacct
    28321 gctgccactg cagcaatgat tccagataca tcaaatgcct ctgccaatac ataggctaga
    28381 aaaggaagca aaagttcgat cagcagatac cctgtgacat cttgtgctga tgctttttcg
    28441 atcaaatgaa ttattttttg tttgaaccag acaagcaaaa agccgatcaa agctccccca
    28501 atactagaaa ctactagact catccccgcg tttactgctg aaaaagatcc ggtgatcagc
    28561 gcaccaagag caaactggaa ggcagtaaca ccagatgcat cattcaaaag accttctcct
    28621 tccaaaatat gcatcgcctt tttagggata ttcactcgtc cagaaagaga actgactgct
    28681 accgcatctg tcggacctaa cgctgctcca aaagcaaagc aggcagcaag tgggacactt
    28741 ggcaacagga atgataacgt cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat
    28801 gccaagaaca aaattgtccc gaaatttttg agaatcgaag aaatatctgc tttttctcct
    28861 tctctaaata acaatggtgc aataatcata actaagaaca attcaggttc aaaatcgatt
    28921 gattgtcccc actctgtcag acctaatacc actccaagga aaatttggat cagtggagct
    28981 ggaatcattg gcaaaatgcg gctagctatg ttcgataagg tgatcgttac tgcaaataca
    29041 ataactaact cagcaaattc catcgtccat cccctttatt ttttattttg tgtaagcatt
    29101 tttaaaaatt gttctttttt ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg
    29161 ttcccctcta attcacactg tacacgtttt gactccaaac gaagcagatc atgtttcaga
    29221 cgttccaact gacgatacat caatatattt cttttacgca acttacaaag tatttgacgg
    29281 cggtcatcca tcgaaagggc gccatagcga tcatgcaaca gttttttttg ttgttcaaaa
    29341 ctctctctca ttttccagat ctcctataca caaacttcca tcattatagc aaagttcttt
    29401 ttggatgaaa aatatttcat tgtttcatcg tttattgcta gttagaaatt tccataaatt
    29461 tttcaacgcc tcattctatt ccaaatagta tcagatatca agtaaaactt aagaaagata
    29521 aaagtttctg acaaaaggat gtttactttc ccattcctgc ctttcttgtt cttttatcac
    29581 aacaaaaaaa tggggctgcg acaaaaatct tgtcacagtc ccttattctg aataaacggt
    29641 gtggaagaga cagcctatca gtagtaataa gacacatctc tttcacagcc tcatttttgc
    29701 gtaaaaatcg atttattcga aaaattcccc gtatacatct tctacacgtt gatctggatt
    29761 gatcacgata tacaagttac ctgttttttc gctgattttt gttgattgat attgattgtc
    29821 taatccttct gttcctttat ctagatatgg gaagtacaca agatcaggtg tgccatttcg
    29881 gtaaaggatt tccattcgct cgatatcttc gtatttcaat gcgcgattaa acatgcccat
    29941 ttccagtccg cctaggttga tatcatgtgt cgcaactgcg tccccttcat ggaagatttc
    30001 gattttaaat ccagcacacg gatggatttc aacaaattca ctgccattga ttcgtccaaa
    30061 acttgttgtg atttgtttga tccaaagatc gccgatatga cggcggttga tcgtccaggt
    30121 ttctccattt ctaaaataaa attttagcgc tgtcatttct ttactcatta aaaagactcc
    30181 tttatgatgt aatttattct tgtactacct cagtttagca caaatttatg taagtggtca
    30241 catcttatgt tttttcttct aatgacgtat ctgcccactt taagtagcca acaaagctga
    30301 gcagatacag tctagtgttt tttaaatcaa tttttctttc gataaaaaat ccaaaacctg
    30361 ttttttatca ttttttattc tttgttctac gacggctttt tcagctaatt gcaaagcttc
    30421 actaacccac ttaccaggtt tttttccagt ttcttctagc aagattttac catctactgc
    30481 taattcgctt aatgacttga taggtaaacg atcataggat tctcctacgg catccatctg
    30541 aggtgtttcg tcaaaataga tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa
    30601 gaagtacaat tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag
    30661 tgcttgaacg tctttaatca tttggttaga acacttccac gatttcaaaa aggaacgaat
    30721 ctcattttct tttagatcca gttggctgat caataatgcc catgcttggc tctcttcttt
    30781 caatgggacg gatggtaatt cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc
    30841 gggacagcaa atgtagcact ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt
    30901 tcccaagagc atcttgatga attccacatt tatacgttct acagatattt tacctaatag
    30961 ctcgtggttt tctttgatgg cgtagaaggt ttcttcctct aatttgaacc ctagttgact
    31021 gacaaaacgc aacccgcgca tcattcgtaa ggcatcttca tggaaccgct catgaggatt
    31081 gcctacagct cgcaagatct gttcttctag atcttgcaga ccatcgaaca aatcgatgat
    31141 ttctccatct tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc
    31201 tgccaacgaa cgaacgaatt cgacatgatc tggtctacgg tagtcctgat aagttgattc
    31261 cgtccgaaat gtggtgatct catattgttc atcattttct aataccaaca cagttccatg
    31321 ttcgatccca atatctatcg tttttggaaa aagctgtttg atttcttctg gaaatgcgct
    31381 tgttgcgata tccacatcat ggattggctg gttcagcaag atatcacgaa cacttccacc
    31441 tacaaaataa gcttcatatc ctgcattctc taattttttc agaactggaa ttgccttttg
    31501 gtattccaga ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc
    31561 ctgagataaa gactcagttg catggtgact gtttgacaag tccgtttcag agtcttcaag
    31621 gccaggacca cttcatcttg tttactcgtc cttacgctca aagcgattat ggtctctttg
    31681 attgaatttt tccatgtttt tttcaaaaac ttcagttaag tcgatattca atgaattagc
    31741 catgatcatc gtaacgaata aaacatcacc aagttcttct gctaccgagt taactggttc
    31801 agaagccttt ttgctttttt ctccataagt gtggttgact tctcttgcca attcacctac
    31861 ttcttcagtt aatcgagcca tctgagctaa tggagagaaa taccccacct tgaattgctg
    31921 gatatattca tccacttcct gctgcatact gtataaagaa cgctttttat ccatcttttt
    31981 ccctccaaaa ctatcttacc aaaactttaa cgcaaatcct agataagagc aattgagaaa
    32041 atcgaatttc catgctacat ttaggaagga atttctaaat ggaaattctg tgaaaataca
    32101 taattgaaag ctggaattca tatggtcaaa cgaaaaacag taaaagaagt tctttttatc
    32161 attataggaa caagtattta tgcatttggt cttgtttact tgaacatcgc taatcattta
    32221 gcagaagggg gagtctcagg gatcaccttg atcttaagag ctttatttgg tattgatcca
    32281 gcttatacga ctttattaat caacatccca ttgattttac taggaggaaa gatcctcggt
    32341 aaacgttcct tggcctatac tgttctaggt acactttctt tgtcattctt tttatggatc
    32401 tggcaaaggg ttccactaga aatcaattta cagcatgatc tactgatcgt ttctctactt
    32461 gcgggtttag ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg aacaacaggc
    32521 ggcagtgata ttatcgctcg gattttagaa caaaattacg gcatcactat ggggcgttcc
    32581 ctattggcat ttgatatcat cgtcttactt gcttcattaa cctatatcga cttgaaacgt
    32641 atgatgtata cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat
    32701 ggcggatatt ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga gattgcacca
    32761 ctactgatga ccggtctgca aagaggtgtg actttccttt ctggagaagg cgcattctct
    32821 ggtaattcaa aaaaaatcat ctatatggtc gttagctcta gtgaattaac tgaagctaag
    32881 aggatcgtcc acgagattga cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg
    32941 gaagggcaag gctttactta tttgaagcca cagacaagat tactgaaaaa actataagaa
    33001 aaaagacaaa gataggctat gaggaaagat tccacatcca gctgaccttt gtctttttta
    33061 gtactatact atttttaact aattgttatg ttcacttacc cggttacttt tcttttgtgt
    33121 ctgcaaaagg atctttcggt taacttcatc agataatttc aaaaaagcat ccctatctcc
    33181 atcttctagt gcttgatcga tttgagcata aagcattttt agttttgcct cttcttcttt
    33241 ttcttgaaaa tatcgttcaa ttaattcagt atcttcttca ctgactgaag aatcccaaga
    33301 agaaaatgga ttgtcttcta agatagatag atattctctt gtctgccaag cattttcgaa
    33361 tatacattcc acatataaag gctttttcca attcaaacgg atttcatgaa aaatctggtc
    33421 tgtgtccgta aattcttttc cctgcaaaaa caatttcatg ggttcccctt caacagatag
    33481 atcactgatc tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt ggacattgct
    33541 taaaatcgct tcatgattgg caagataatt caagatccaa aaaacttctc ttcggctaaa
    33601 agatacatga ttgaccatcc acgttaaaaa attcttcttt tcccgtacat caattagcat
    33661 ttttctcacc tctctgttag gtcatctaat aatgacagtg cctccatatc tcctggttca
    33721 agtgttaaat aataagtcaa taattcttgc gctcttttca gctgcccttc ttctcttaag
    33781 aaaaaggcat actctttcaa gaaatctggt tcatgtgata gttcatgata agcctgttca
    33841 tagtgtacag ctgcaacggt aaagtcttct aattcattat aagcatgggc taggttccat
    33901 tctgcataag gattagcagt ttcttccatc tgattgatca cttgtatcac atcttcatat
    33961 ctttcatcat ccaagtaaag attacttaaa gtaagtaatg tttcatcttg tttgtctcct
    34021 acttctaaag ctttcagtaa aagttcttct gctcgctgtc tatcatgcag acggaaagca
    34081 ttttccgagg ccaggtgata aagttcgact tggtaaggat tttctttgat tccttcttct
    34141 aacactgttt gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc tagatataga
    34201 tataacgatt gataatgcgg attaacttct cgaagttctt ccagatagtt gattgcctgc
    34261 tgattttctt tcaattgaag attcgtaaaa gctagctgga acagtcgatc atctgtcctt
    34321 tcttctttca gtgcttcttc taaaggtacg atagctgctt cgaattctcc ttgcatactt
    34381 aaggattgtc ctaaacgttc ctgcatcgag attcctgaaa tttcatttat cccgcttgcc
    34441 aacaatgttt cataaaccac tgctgcctct ttgaaacgat caactgaaaa atacaattca
    34501 gctagcgcaa actggatcaa tggttcatca ggaagcaacc cagctgcttc tttcaatttt
    34561 gcttcactca cttcagggat tccgataact tggtacaaat cagctatcgc caataagctt
    34621 tgcggatagt aatcactttg cttatccact ttttccaggt attcaaaagc taagtcgatc
    34681 tcattatctt cgattgcaat ttctgctaac gggatgttca gtccgtcatt ttctgggtat
    34741 tggttgatca gttgttcaaa aatctgtttt gcttcgatca aaaagccaat agccagcaat
    34801 tcttcgccta gttcagctaa tatatctgct gggtcttctt ttaatgcttt ttctaaaaag
    34861 atttgtgctt gtgacaagtc ttcatctgat aaagcttgca acattttttc gctatttgta
    34921 ttcatttcaa ttccctctta tctcactgac gatttgttga aataccgtca ttgttctcaa
    34981 taattctttt tcgtttggat gttggtatcc gtctattata cctatttttt ctaaaacaag
    35041 tatttttttg cttttttctg ccaaaaaaag aactttttcc aaatactcca tctttgaaat
    35101 ctgttccagc cagtggattg gatagccaag caagtccagc cacacaaaaa agttttttag
    35161 ttggaaatca aaaggatatg cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa
    35221 ttttttcata ctagcagaaa gtagatggcc attttcggtc agataaaaag cttgttcaaa
    35281 cagtttacca taatttgaca ggttttctgc ctctaattga taaaaataga tcatttcttc
    35341 gatcatcccg gcaaacggcc gagtcgttaa ttgcttttta tttggatagt ttttatacag
    35401 attttgcaaa aaacgatgat cacaaatcat tccgcaacag ataaaagtca aaaagtcaat
    35461 ctgctttccg tccacctgcc gctcgctgat tgtttgatca taaacgatgc gttctggcag
    35521 attgatggtt tgcagcacta cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa
    35581 tgctcggctt agagaacgga tcgatacagg gatcatccat agtgatgaat caagggttgt
    35641 atgtttttga aaaaaacctg ccagatccat gatcccttca tttccaaatc cgatgataaa
    35701 catggattga ttttcgggat agcgtttgac gaaatcaagc aggttcttta attctgttaa
    35761 atgattgcat tgagtgttgg cacaaatata ccagtcattg tttgcttgat ttgcaaataa
    35821 cgggttgatc ttatctgcaa acaaatcata atagcgctga ttcgttaaaa ataagattgg
    35881 ctgatcaatg gaaagttctc ttagctgact gactagcgtt tctccgtaaa acactttcgt
    35941 caacgcatct tctacttgat aatcaagttc catacgcatc cctcctcttc ttatttttat
    36001 tttaccatta gtaagcaaat tctagaaaag ataagagcaa agctcacctc ataacttgca
    36061 aataaataaa aattaaataa aatacatgtg ttttctatgt atgacatacg gattcggaat
    36121 ctctgtctct tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct
    36181 agagccacaa gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg
    36241 tttgaatgca ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg
    36301 acctttgcga gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt
    36361 ttcgccgtta gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc
    36421 atctttttta gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc
    36481 catggataga ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt
    36541 tctgagtggt ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg
    36601 atatcatatg aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc
    36661 atagaaacgt aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa
    36721 aatgcctatt ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct
    36781 tttctgattt gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg
    36841 acaaaaacga caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg
    36901 cgttttcctt tatctgttgg tgttggattg attgctacag catccataat gatatcattc
    36961 aacacagccg aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc
    37021 agacgttcca accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga
    37081 taccggaatt catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt
    37141 acaagatccc atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc
    37201 gctactcgct tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata
    37261 tcagaacggt caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat
    37321 acttttccgc gtttacgcat accagctgta tctatcatta agaatttctg accactttca
    37381 gaaacgaagt gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca
    37441 cgttcttctc ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc
    37501 aaactaaact taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact
    37561 gcttcatcta aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg
    37621 cctagcccta aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta
    37681 ttgactgcta aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct
    37741 gcgtctgtca cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc
    37801 gcgatttctg cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg
    37861 cctgtgtcga tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca
    37921 cgagttactc caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa
    37981 atcgtagact taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta
    38041 tttcctcctc acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag
    38101 catagattgt caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca
    38161 aaagaaaaac tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta
    38221 tttttcagaa tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat
    38281 gtctcccata gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg
    38341 ttcttcttct gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc
    38401 ttctggatgg atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg
    38461 tggtgtcgca atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg
    38521 gaacacttca acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt
    38581 gccaactgga gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga
    38641 caaggaaaca cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt
    38701 gacagccaat acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac
    38761 tagaccgtca attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg
    38821 tccactgaga acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct
    38881 ttcgttttcc actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc
    38941 gatgatttta aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc
    39001 ttccaccatt gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt
    39061 gacaacattt gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc
    39121 ttcccaaact tttttagcat ctaaacggcg ttttgaaagt agatagctgc cgttttcttt
    39181 atctttgccg atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc
    39241 gctgatatct tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc
    39301 agccccttcg attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac
    39361 aacatcgcca acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt
    39421 ctcttgattt tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta
    39481 agtacggtac tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt
    39541 tttccttgaa aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct
    39601 tttttcaaaa caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta
    39661 tcgatacgaa cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa
    39721 tggtctcttt cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct
    39781 tggttctctt tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc
    39841 acttctgcat tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg
    39901 cgttccccta tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag
    39961 acttcagaaa cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat
    40021 gctatgaata catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc
    40081 agcgaaacta gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt
    40141 actgcgcgat acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc
    40201 ttggcaacgg tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc
    40261 atgatataac tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt
    40321 cttaattctt gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac
    40381 aattgatcag tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga
    40441 acagtcgttg ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg
    40501 cttgaatccc ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca
    40561 atactgcttt ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta
    40621 ctagattcta ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct
    40681 actactgatg tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt
    40741 ctgatccaga aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat
    40801 agcgaaagaa ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact
    40861 tcatcatctg tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta
    40921 gattgatgtc tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat
    40981 accataggaa aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat
    41041 ttagtaaaat cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca
    41101 gaagttctgc ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt
    41161 cgccaaaata agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca
    41221 tctgctgcag gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt
    41281 ctggtttttc agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag
    41341 cttgctctgt ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt
    41401 gattaaagaa ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt
    41461 cttcctgatc tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca
    41521 aatcataatg gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg
    41581 tagcaatgag aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag
    41641 ctgcatcaag accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca
    41701 atcgttcgac ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca
    41761 tgaagtgttc aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt
    41821 gccgattgac tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat
    41881 ctcttgctac taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa
    41941 gctttcggat ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca
    42001 cgcaatgagc ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa
    42061 gagaaggatt agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac
    42121 ggaggacgta tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct
    42181 cccctcgttt ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga
    42241 tgatgaccag accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc
    42301 ctgtaggcaa aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt
    42361 ggccgggacg aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt
    42421 atcgcttcct ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt
    42481 ccatctacat tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa
    42541 cgttcgattg tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc
    42601 cactcaataa gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg
    42661 tcaattgtct gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt
    42721 tgctgtaata atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt
    42781 gctaacaaaa ggtggataca tctgctttgt tgcagataaa ccgctgactc atcattgttt
    42841 tttgccagct gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa
    42901 aaatctgctg cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta
    42961 tcaatcaaaa tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta
    43021 taaaaaggac ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt
    43081 acttgaacag caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca
    43141 aaacgcaaac cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt
    43201 agctttgctt cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt
    43261 tgataaaact tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg
    43321 gtaaatccat aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa
    43381 ctaatccgca gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc
    43441 tccttaagtt aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta
    43501 ttgcatgcgg tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa
    43561 tcgttttatt tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa
    43621 catatgtaaa aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa
    43681 tataaatata aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc
    43741 gggatctgtt tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc
    43801 tatagttaat tgactagttt tttcacggac cctataggac ccatttatat tatttcaact
    43861 ttttcagcca gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt
    43921 ctgcctctcc atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat
    43981 tgattgatac atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct
    44041 gattcaatac tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca
    44101 atgttccttt tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg
    44161 aatgattctt attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca
    44221 cataatcgga atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg
    44281 ctagatcaag tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg
    44341 cccaaatact ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag
    44401 actttccatg attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt
    44461 cttttaccaa cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat
    44521 aaccggctcc accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata
    44581 ttttcacttt ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt
    44641 ataccttaaa aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga
    44701 atatccattt gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata
    44761 cacagcttct gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt
    44821 cgcctggtgc ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt
    44881 catcgtacga gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat
    44941 atcgcgatat gtccccaata gatttttcac taactcactg tctagtggca cgtataatga
    45001 atcaaggaag tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt
    45061 agctactaaa tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt
    45121 ttgttctggt gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc
    45181 ttctgttttg cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa
    45241 attgattggg ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt
    45301 cactccttgt gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc
    45361 ttgttcttcg aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc
    45421 tccagagtaa ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa
    45481 ctcgttcgtt cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa
    45541 aggaaattca gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt
    45601 ttctaaacaa cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt
    45661 gaattccacg ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc
    45721 tttgtcatct tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg
    45781 ttttgtttcc caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc
    45841 gaataattca tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa
    45901 tgttctaaat cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt
    45961 tttaccgaag ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat
    46021 caattcgctc aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat
    46081 gatattatcc tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt
    46141 cttctcaaat aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat
    46201 gatgaaagaa aaaacactca ctgaatggag ctattgactt atccacgtgc ttatcgatag
    46261 ccgtttatcg gtttcttcat tcttatgata gaccttgtac ctgtatttgt ctaggtttag
    46321 aacattgctg ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta
    46381 ccggtaaatt tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg
    46441 atagcagatg ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt
    46501 actaaatcct taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca
    46561 gcagctaagc cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta
    46621 ataatgatga atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg
    46681 gtgtctgtga ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg
    46741 attgctacac cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct
    46801 ttcatgccat aagtgattgc tactacgatg gacattacta agaataacat agtaatttct
    46861 gggaagtacc agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga
    46921 aggtttgtta accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc
    46981 caaggaatca aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt
    47041 ttttgttttt tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata
    47101 tcttctttac gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca
    47161 taacgataca catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga
    47221 ccaatacctt cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga
    47281 tttaccgttg aagctagaca gcctacttga gaccctacta atacgattgc tacagctact
    47341 actgtatcaa agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt
    47401 tcttctgcca ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata
    47461 agcatttttt cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc
    47521 cctgttttgt tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg
    47581 attgcagcag gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt
    47641 ggcgccatga aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca
    47701 gcgacgatgt tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt
    47761 acagcgatta ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt
    47821 ttcttttttg tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg
    47881 gctctaatgt tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta
    47941 aaacttttgt tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa
    48001 gctttcttct ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt
    48061 aaaaggagaa gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa
    48121 aatactcaaa acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa
    48181 aaaaaaagac caagaaattt cttgatcttt ttgatattta tttgactgct gtatgacgtt
    48241 gttcgaactg atgttgtttt cgacttaacc atggaagaag ttgcgcatgc agcactaaaa
    48301 agacagcact cacgatgaat cctttgatca agttgaaagg aacgatccca atcagtacat
    48361 agtttgctaa agacatgccc agcatctgtg ttgcgttcag ccctaaaaac attaagtaaa
    48421 gaggcgtaat aacgaaataa tttgcgatac tcataaaaat agttagagcg atggttcctg
    48481 taatgacacc taaaaatttg tttcttcctt tatgctgttt ctttacacta aagaaataat
    48541 aaatcgggaa tgtaaagatc gttgttgata agaaactagc agtgtctcct accaaattat
    48601 ccggagaaaa acctgtagtc agcagatgta atactgaacg caagaacgct gttgcaactc
    48661 cggccgctgg accgaataag aacatgctga tcaataccga gatatcacta aaatcgatct
    48721 tcaaaaaact aaaagccggc atgatcggaa aagcaaaata ctgtaaaact aatgcgatcg
    48781 cagcaaacat cgctactgca accattttct gtacacgggt gttcttcatt tgaaatcctc
    48841 ctgttaggac tcctcttcag cgaacttttt gacgtttctc tccaaatgaa aaaactctat
    48901 tttccaggga aaatagagtt agagttattt gatcaagcgt cgtcaaataa gctctatctt
    48961 ctttatccag actatactgt cggtatcgga atttcaccga ttcagctatt tttttgcaaa
    49021 ataggtcgtg gactataacc accggtcggg aatttcaccc tgcccctgaa gacgaacctt
    49081 atataatttt tgtttacata ttcattatac atatctattc aaaaaacgca acatctaaca
    49141 cttataaaaa gtaagtgttc attttgagtg gttcagcaaa ctgctgactt cttttttgtt
    49201 cagttcacgg taatccccag gacgtaggcc ttgtaaagtc agatctccgt atttttcacg
    49261 ttttagtttt tgcacaggaa gaccaactgc ttgaagcata tttttcactt gatgattacg
    49321 tccttcgtgg atcgtcaatt ccacgatact gtggtttgtc ttaggatcca ctgataaaat
    49381 ttggaattta gctggagatg tttttcgtcc ttcgatcttt attccttttg tcaaaggtgc
    49441 aagcatcgat tttgtagcga tcccttttac ctttgcaacg taaactttat ccacttcatg
    49501 ttttggatgt gtcaggcgct gagcaaaatc tccatcattt gtcagtagca agatccccga
    49561 agtatcgtaa tccagtcgac ctacaggata gatacgttct tttaccatcg gcaaaagatc
    49621 cgtaacaact tttcttcctt tgtcatctgc aacagcagaa ataactcctt taggtttgta
    49681 caataaatag taaccgtatt cttcttgata aattgggact tcatccactt ccacagtgtc
    49741 atgtttccca acttttatcc ctaattccct tacaacttgt ccgtttactt ttacacgtcc
    49801 tgcaaggatg aattcttctg cttttcgacg agaagtgatg ccagcgtggg caattacttt
    49861 ctgcaatctc tccattacaa ttattctcct ttattcattc catcaaagaa tagatctggt
    49921 gacacgtctt cttcaagtga aatttccatt tcttgtgtat caggcagttc ttctaatgat
    49981 ttcaaaccaa aataatctaa gaagtagcca gttgttccat ataatatcgg ccgacctggt
    50041 ccttctactc tacctttttc ttcaatcagt ttatgggcag ctagacgctg taccgctcct
    50101 gaaacctgaa ctcctcgaat ctgctcgatt tcagctcttg tgattggctg tttataagcg
    50161 atgattgcta aggtttcgac ggcggcttga gataatgtgt ttgatgtccc ttgcgcatat
    50221 cgcttaagta agggagccag ctctttttta gtcgttaata cataatggct ttccgtttca
    50281 aaaatatgca aagctgagtg cgagttttga gtgtaagatt cttttaattc tttcactaaa
    50341 cttgtgactt ctgcttcgct gagatttaac agtccgctta attcttcatt actgatccct
    50401 tcctcgccaa caataaaaag aagggcttca agttcactta atttcgtcat gttcggtatc
    50461 tcctactgct ggataaagca taattgattc atagttttct ttttgttgcg caatgatctg
    50521 cccttttttc atcaattcta gcaaagccat aaaagtagtg acaacttcac ttttagaagg
    50581 tgactcaaaa aaagaatcga aagtacagcc atgcgcattt ctttttatac gctcttcgat
    50641 aaataccatt cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt ccactttttg
    50701 agaaaatttc ttacgttcta agattttctg catggcacgg atcaaatcga tttttttgac
    50761 ttgtcctcgc ttcaacggct tttcagcatc cgctaaccca tcgatgttca taggttcttt
    50821 tgtgtaataa agacttcgtt cctctgcttt ttctgtcagt ctttcagctg catatttata
    50881 tttacggtat tctaaaagct gagtgaccaa ttcttctcga ggatcttctt cccataattc
    50941 ttcatcgtct gtgacgaatt cttggacagg aagcaatgtc ttgcttttga ttgccatcaa
    51001 tgtagcagcc atcactaagt attctcctgc aacagctagc tcgagtgttt tcattgtatg
    51061 gatataattc atatattgct ccgtgatcgt agcgatcggt atatcatata tatcgatttc
    51121 catttgctga atcagatgaa gcagcagatc gagaggaccc tcgaatacat ctaatttaat
    51181 attgatctcc gtcaactcat tcactctttc ttctttttct ttgctagcca ttttccaatg
    51241 taaggctctg tgatttcagt tgcacggatg gagacatccg ggtacttttc ctgtaattca
    51301 tctaacattt gaaagcccat attctcaccg cgataagacg gattcaaaga aatgtcatgg
    51361 atgatcagct gatcgttcgt tgcccagtaa ataccaataa tcccttgaat gttggttgaa
    51421 ccttctggcg taaagaaaaa aagttcataa tcgtcttcag attcgtacgt atcaatctcc
    51481 ttcaacaaag aagttttacc tgtcagtttc ttatggaaac tcaatagtcc catagcaatt
    51541 ttacggtttt ctttccggta atgtgttaac atcttctcac cttcctatga ctaagccctt
    51601 ggaaaatgct gcttataaac atccgtcatt cttttcttcg tgatatgtgt ataaatctga
    51661 gtcgtagaga tatccgcgtg acctaacaat tcctgtactg tccgcaaatc agctccattt
    51721 tctagcagat gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc tttgtaaatc
    51781 ccagcctctc gtactaactg cttcagattt ttccagattc cttgccgaga aagacctttc
    51841 ccatgattat tgacaaatac atgcatttca gatgcgtcct ttacaagtaa tggacgtgct
    51901 tcgtctaagt agcgttccag ccattggatc gcataatcac ctaaaggaat gatccgctct
    51961 ttatctcctt ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc tcccaatttc
    52021 aatccaatca attcactgac gcgcatccca gtagcataca tgacttccaa gattgcacga
    52081 tctcttatcc ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc tacttctgtc
    52141 agagtcaatg tacttggtaa tttctgtgct ttcttcggcg tatcgatatg ttgcatcgga
    52201 tcatgatcag tgatacgctc ttgccgtaaa aactgatgga atcttctgag acttgagatc
    52261 atccgagtaa cagttgctgt cgcttttttt tcttcatgca acttctccag aaaacggatg
    52321 actaaaaagc gatcgacatc ctgccatgaa gcaattttct gctcctgtag aaaatgcaag
    52381 tactgttcca aatcacgttc atagctttgt cgtgtattgg cggacaatcc ccgttcaata
    52441 ttcaagtagt ggagataatc gttgatttgc tctttcataa taatccccct catgcctctc
    52501 tatcatatca gataccgctt cattctgata gtctttttcc ataatctgag caaagaaaaa
    52561 gccgtctaga cactcagacg gactggtttc ttttttcttt ttcatagcat tcctgacaga
    52621 ttccatggaa cgttagccga tgatctttta ctaaaaaatg ataacgttct tctactactt
    52681 gctccacttc aagtaaaaga tcctcttcta cttcctcgat cgtgccgcag ttcaagcata
    52741 gtaaatgatg atggaaatgt ttggcgcctt cttttctcaa atcataacgg gctaatccat
    52801 cattaaaact tactttatcg acaattttca attctgtcaa gatttcaagg gttcgataaa
    52861 cagtagcaag tccaatttcc ggactctttt ttttcactaa aaagaagatt tcttctgcag
    52921 ataaatgctc tttctcattt tccaaaagca caagcagagt agcttctctt tgcggtgtca
    52981 gcttaaaccc cgcttcatgt agctgctgtt ttgttttttt catcgccgaa atagcattca
    53041 tgaccattta ctcaacccca acaatttata ataattacaa ataaaaaaag atataacact
    53101 atgttaatta aaattattat aagctagtta agaaaaacat gcaagggatt ctcaattaga
    53161 ttttttgact agttttgtca caccgttttc ttgtgtaatc aatccttgtt tcaaaagatt
    53221 acctaatgcg cgcttaaatg ctcctttgct gataccaaaa gctttcatga tttcttctgg
    53281 atccgattta tctgtaaagt tgatttgctg atctgcagaa cgttctaaaa tggttaaaat
    53341 catttgtgca tcatctgata tagcttcata tgctcttggc ttcaatgaaa gattcagtac
    53401 accgtctggt cggacaccaa tcactcgacc ttttatctgc tcgcctagac gaggttcatt
    53461 atatcgttca gaaggatgga taaacccaag atagaaatct tccgttaaaa cgtacgtacc
    53521 tgttaatttc aagcggtatg ctgttcctat cacatctttg tttttcattt cttctgttcc
    53581 atatttgctt aaagatttga atattttttc atctgctaaa ctgccccaaa tacggtcttt
    53641 tgcatcaact ctaagggaaa tcatcaagcg atcccctttt ttaggccata gctctgtcat
    53701 tgtcggcaat tcatcaagag atacgacaaa gtctttatct ggaagaccga tatcgacaaa
    53761 cgcacctaaa tcttttcgtg tagcagtaac gattccaaaa ccgtaatgac cgatacggct
    53821 tttaggaatt tgtgtagtga tccgattttc atgtttttga ttttggtaac cgaatccttc
    53881 aactgcttca ccgattttgt gttcaccttc tgatttgctt aagccaaagg tttgtccgtt
    53941 tttttggaca aagtagtttt tttcattttc atcaataata atacctgtaa atatagttgc
    54001 taataaatcg ttcatttttt tctccctcta tagtgaaagg ttttcttaat acatttcttt
    54061 gctatcataa cataatgtta tctacttgaa tagctgagcc ttggtttgga aaggtgaaaa
    54121 aaggagtatg acaacagttg tgtcatactc ccctttttcg aataaacggt gttaaacggc
    54181 aggctcacag cctctttcat ttgcctaaaa ttaattgctc ccatttcctc cgaaccatcc
    54241 agttttacag ttgatggtta cgatgtaaaa tggcaaagca ctttctccaa tgcctttcat
    54301 caatgcagat tttgttgaag tggcatatag attataatag ccttccccat tttcgattct
    54361 ggctttttct aatctgtaac ctccttcaac gatatatcca cgttggatac atgtagcaat
    54421 cactttgctt tggacacctg gtgcccacgt ccatgctgga ttagatgcat cggcaatatc
    54481 acttgctctg gcagatttga ttggctgatt cgctgagttt gaagaggaag gggtcgagga
    54541 tgccgcttct tgctgtgctg cttgtgcgac cgcagcttgt tgagcggctt gagctgcagc
    54601 tgctgcttga gcggcttgtt ttgcttgttc ttcagctgct tttttcgctt cttctgcttt
    54661 tttcttttcc tcttcttctt ttttctcttt atcagtgagc atcttatcta cttgtttcaa
    54721 ttgttcattc aactgagcag atagatctgt atttttcact ttttctactg cttcttttgc
    54781 cgtcttgtat tggtcgcgtg ttgctgaatc cactactttt ccgtctttaa agactatagc
    54841 tgttttttct ttagctgttt gcaattcagc atattgattt ttagcttctg tttgtgcttg
    54901 ttgaatcaat tttccaaaat ctgtgttatc cgtttcgatt gcttggatct ctttatctgc
    54961 tttcaacttg atgtcatctg ctagatgatc atcgacgatg gcaggtgcta tgaaccactc
    55021 attcactttt tggatatctc ggatcttaga ttggatatct tggtaagttg tttctaactc
    55081 tgaatatcct ttttcattct taagactgga taaatcattt tttagttttg ataaatcttg
    55141 atgaatcata tctgcacgaa taaattgatg gtgatcatct gtataaaagg cagcaagttt
    55201 ctcatgaagt tcttccattt gttgctgtct ttttgcttct gctgctactt cggcttctac
    55261 tttttgatga tggtcataat aagcccagct tcctccaccg agtagaagta ctgctgctaa
    55321 aacgagataa ggtacttttt ttgatttttt cttttgcgct ttatctggat ctgttttttc
    55381 taagtttgat tcttgatgtg ttttttcagt atctggcacg attgttattg atttcgcttc
    55441 tgcttcaaac agcttaggct ggttctcttc tttttctatt tttgcttcaa gatcagtacc
    55501 ctctttgctt acagattgat tttcagcatc ggattcacta tttatttcat cgggctctgt
    55561 tgactttttg tctgtgtttt cgagtatttc ttttttctct gcttccggca gtttattcgt
    55621 tttttccttt tctaattgtt tttcagtaaa tacttcagtt ttttctgtga tatccgtttt
    55681 tacgtctttt atttttactg tttctttacc tgtggcgttt tctctatcag agtctttttc
    55741 agtttcttgt tccttttctg gctctacttt gttttcctgt gcaatttttt cactgatcat
    55801 tttgagcagc tctttcgcgt gctcttcttt tgtatcttca cgatgtgctt tgatataagc
    55861 ggatagtatc gaattttctt cctcattatc gacgatttct ttcagttcag ctactcttct
    55921 tttttgtttt gattcaagcg tttcttcttg attctttcct gattcttccg aagtctcatg
    55981 aacagttgct ttcttctgtt catttttctc tatattagtt acttgatcgt gagcaggtgg
    56041 ttcttcgtct tctggttctg ctttttcgaa taattccatt acagattcta gaggtaaatc
    56101 tttcaattcc gaccattcga ttggatcgtt taattctgta tcaggaaaga ctgcatcttc
    56161 agttgattta tcctgcatag ctgcatctgt atttgtttct tcaattgatt cttttatttg
    56221 ctgatcttct gcagttattt gatgaccgca gtctggacag atagtattct gctccatttt
    56281 tttcgatccg caatttggac attttttcat cacttagcga tcggctcctt tactaggttt
    56341 acgctaccat ttaatctatc atattctata cgtcacgcca atagcttatt tttaggattt
    56401 acttaaaaat aatgaatgaa tttccttcct atagaaaaaa aagcttgaga ctgcgtagtc
    56461 tcaagctttt
//
LOCUS       DACGLI010000012        51743 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.013, whole genome shotgun sequence.
ACCESSION   DACGLI010000012 DACGLI010000000
VERSION     DACGLI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.013"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(115..918)
                     /locus_tag="IXT22_000800"
     CDS             complement(115..918)
                     /locus_tag="IXT22_000800"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAQ4862184.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(938..1780)
                     /gene="kduI"
                     /locus_tag="IXT22_000801"
     CDS             complement(938..1780)
                     /gene="kduI"
                     /locus_tag="IXT22_000801"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAQ4862185.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKESEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(1796..2803)
                     /locus_tag="IXT22_000802"
     CDS             complement(1796..2803)
                     /locus_tag="IXT22_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4862186.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(2810..3454)
                     /locus_tag="IXT22_000803"
     CDS             complement(2810..3454)
                     /locus_tag="IXT22_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4862187.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(3554..4312)
                     /locus_tag="IXT22_000804"
     CDS             complement(3554..4312)
                     /locus_tag="IXT22_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAQ4862188.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(4439..5590)
                     /gene="fucO"
                     /locus_tag="IXT22_000805"
     CDS             complement(4439..5590)
                     /gene="fucO"
                     /locus_tag="IXT22_000805"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAQ4862189.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(5672..5983)
                     /gene="rhaM"
                     /locus_tag="IXT22_000806"
     CDS             complement(5672..5983)
                     /gene="rhaM"
                     /locus_tag="IXT22_000806"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAQ4862190.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(5985..6830)
                     /gene="rhaD"
                     /locus_tag="IXT22_000807"
     CDS             complement(5985..6830)
                     /gene="rhaD"
                     /locus_tag="IXT22_000807"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAQ4862191.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(6844..8100)
                     /gene="rhaA"
                     /locus_tag="IXT22_000808"
     CDS             complement(6844..8100)
                     /gene="rhaA"
                     /locus_tag="IXT22_000808"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAQ4862192.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(8097..9557)
                     /gene="rhaB"
                     /locus_tag="IXT22_000809"
     CDS             complement(8097..9557)
                     /gene="rhaB"
                     /locus_tag="IXT22_000809"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAQ4862193.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            9710..10579
                     /locus_tag="IXT22_000810"
     CDS             9710..10579
                     /locus_tag="IXT22_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4862194.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(10705..11604)
                     /locus_tag="IXT22_000811"
     CDS             complement(10705..11604)
                     /locus_tag="IXT22_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4862195.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(11769..12593)
                     /locus_tag="IXT22_000812"
     CDS             complement(11769..12593)
                     /locus_tag="IXT22_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4862196.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(12604..13899)
                     /locus_tag="IXT22_000813"
     CDS             complement(12604..13899)
                     /locus_tag="IXT22_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAQ4862197.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(13915..14394)
                     /locus_tag="IXT22_000814"
     CDS             complement(13915..14394)
                     /locus_tag="IXT22_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAQ4862198.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(14400..15428)
                     /locus_tag="IXT22_000815"
     CDS             complement(14400..15428)
                     /locus_tag="IXT22_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAQ4862199.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(15445..16551)
                     /locus_tag="IXT22_000816"
     CDS             complement(15445..16551)
                     /locus_tag="IXT22_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4862200.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(16780..19377)
                     /gene="adhE"
                     /locus_tag="IXT22_000817"
                     /gene_synonym="adhC"
     CDS             complement(16780..19377)
                     /gene="adhE"
                     /locus_tag="IXT22_000817"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAQ4862201.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(19682..20062)
                     /gene="yajC"
                     /locus_tag="IXT22_000818"
     CDS             complement(19682..20062)
                     /gene="yajC"
                     /locus_tag="IXT22_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAQ4862202.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(20159..21304)
                     /gene="tgt"
                     /locus_tag="IXT22_000819"
     CDS             complement(20159..21304)
                     /gene="tgt"
                     /locus_tag="IXT22_000819"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAQ4862203.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            21521..22219
                     /locus_tag="IXT22_000820"
     CDS             21521..22219
                     /locus_tag="IXT22_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4862204.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(22387..25026)
                     /locus_tag="IXT22_000821"
     CDS             complement(22387..25026)
                     /locus_tag="IXT22_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4862205.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(25645..26676)
                     /gene="queA"
                     /locus_tag="IXT22_000822"
     CDS             complement(25645..26676)
                     /gene="queA"
                     /locus_tag="IXT22_000822"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAQ4862206.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            26869..28044
                     /locus_tag="IXT22_000823"
     CDS             26869..28044
                     /locus_tag="IXT22_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4862207.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            28048..28689
                     /locus_tag="IXT22_000824"
     CDS             28048..28689
                     /locus_tag="IXT22_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862208.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            28686..29603
                     /locus_tag="IXT22_000825"
     CDS             28686..29603
                     /locus_tag="IXT22_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4862209.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            29600..30271
                     /locus_tag="IXT22_000826"
     CDS             29600..30271
                     /locus_tag="IXT22_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862210.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(30812..31300)
                     /locus_tag="IXT22_000827"
     CDS             complement(30812..31300)
                     /locus_tag="IXT22_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAQ4862211.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(31501..31767)
                     /locus_tag="IXT22_000828"
     CDS             complement(31501..31767)
                     /locus_tag="IXT22_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4862212.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(31767..32030)
                     /locus_tag="IXT22_000829"
     CDS             complement(31767..32030)
                     /locus_tag="IXT22_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4862213.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(32023..32295)
                     /locus_tag="IXT22_000830"
     CDS             complement(32023..32295)
                     /locus_tag="IXT22_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862214.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            32506..32691
                     /locus_tag="IXT22_000831"
     CDS             32506..32691
                     /locus_tag="IXT22_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4862215.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(32833..34656)
                     /locus_tag="IXT22_000832"
     CDS             complement(32833..34656)
                     /locus_tag="IXT22_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAQ4862216.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(35253..37958)
                     /locus_tag="IXT22_000833"
     CDS             complement(35253..37958)
                     /locus_tag="IXT22_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAQ4862217.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(38264..39211)
                     /locus_tag="IXT22_000834"
     CDS             complement(38264..39211)
                     /locus_tag="IXT22_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAQ4862218.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            39401..39670
                     /gene="rpsN"
                     /locus_tag="IXT22_000835"
     CDS             39401..39670
                     /gene="rpsN"
                     /locus_tag="IXT22_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4862219.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(39846..40208)
                     /locus_tag="IXT22_000836"
     CDS             complement(39846..40208)
                     /locus_tag="IXT22_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4862220.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(40219..41340)
                     /locus_tag="IXT22_000837"
     CDS             complement(40219..41340)
                     /locus_tag="IXT22_000837"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAQ4862221.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(41356..41706)
                     /locus_tag="IXT22_000838"
     CDS             complement(41356..41706)
                     /locus_tag="IXT22_000838"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAQ4862222.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(41836..43347)
                     /locus_tag="IXT22_000839"
     CDS             complement(41836..43347)
                     /locus_tag="IXT22_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4862223.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(43669..45021)
                     /locus_tag="IXT22_000840"
     CDS             complement(43669..45021)
                     /locus_tag="IXT22_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAQ4862224.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(45174..46250)
                     /locus_tag="IXT22_000841"
     CDS             complement(45174..46250)
                     /locus_tag="IXT22_000841"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAQ4862225.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            46446..48191
                     /locus_tag="IXT22_000842"
     CDS             46446..48191
                     /locus_tag="IXT22_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAQ4862226.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(48471..48908)
                     /locus_tag="IXT22_000843"
     CDS             complement(48471..48908)
                     /locus_tag="IXT22_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAQ4862227.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(48892..50265)
                     /locus_tag="IXT22_000844"
     CDS             complement(48892..50265)
                     /locus_tag="IXT22_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862228.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(50587..51075)
                     /locus_tag="IXT22_000845"
     CDS             complement(50587..51075)
                     /locus_tag="IXT22_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862229.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(51097..51699)
                     /locus_tag="IXT22_000846"
     CDS             complement(51097..51699)
                     /locus_tag="IXT22_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4862230.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        14583 a        11284 c         9331 g        16545 t
ORIGIN      
        1 gcttctgtcc cagcctcttt tttcgaataa atgatgttta atcagctgtc cttcggtatt
       61 cgttcaatcc gctgatttca caacctctcc actaaacagt gtactaaagc tcttttaagg
      121 ttgttttccg atataggcaa gtatgcctcc gtccacatac aagacatggc cgttaacgaa
      181 atcagatgcg ctagaagcca agaagacaga tggtccagcc aaatcgattg gctcgcccca
      241 gcgtgctgct ggcgtacgtc caacgataaa ttgatcgaat ggatgacgtt caccgttttc
      301 ttgtgtttcg cgtaatggag cagtttgcgg tgtagcaata taacctggtc caattccatt
      361 acattggata ttgtattgac cgtattcaga agcgatgttt ttcgtcagca tttttaatcc
      421 gccttttgcc gcagcataag cactgaccgt ttcgcgtcct aattcactca tcatggagca
      481 gatattgatg attttaccgc cgcctttttc gatcatatcc ggaataactg cttttgaaac
      541 gatgaatggg gcatttaaat ccacgtcgat tacttggcgg aagtctgccg catccatttc
      601 gatcatcggt gtccgtttga tgatccctgc attgttgact agaatatcaa ctgaacctac
      661 atcttctttg atctgttgaa ccatcgcttg aaccgcttct tcatcggtca catcgcagac
      721 ataacctttt gcatcgatgc ctgcttcttt ataatgcgct ataccttcat caactgattc
      781 ttgattcaag ttattaaata cgatttttgc tcctgctgta gctaaagagc gtgcaatctc
      841 aaatccaata ccatagacag caccggtgac taatgctact tttccatcta aacgaaacat
      901 atccatacta aattccatca ttttctctcc cttatgctta ttttaattga tccatttgca
      961 ccatatccat gtctgtatag gtgatatttt ctccgcacat tgcccagatg aatgagtaat
     1021 tgcttgtacc tacacctgaa tggatcgacc agcttggcga aataatggct tgttcattgt
     1081 ctacaactaa atgttttgtt tcatctggtt tgcccatcat gtggaacaca cgtgtatctt
     1141 cattggcata atcaaagtag acataagctt ccatacgacg ttcatgtgta tgacaaggca
     1201 tcgtattcca agcgcttcct ggttctaaaa tcgtataacc catttgtaat tgacagcttt
     1261 cgcatacatt tggatggatg tattggtaga ttttacgttc attcagtgtc aggccttcac
     1321 cagtctccat tggttttact tggtcgatac tgatttttac atttggatat ttatgatgag
     1381 ctggaacaga actaatatag aatttagctg ggttttcagc atcttgagaa gaaaatacaa
     1441 catgtcgtgt ttcttttccg atatagtatc cgtcttgttt tttcatttct tctttttgcc
     1501 catcgatctc gatgaatcct ggtccaccga tattgatcac acctagttca cgacgctcta
     1561 agaagtaatc aacacctagt tctttgtcta atgtgatttc tgattctttt tcagtaggtg
     1621 tcactccacc aaagatcatt cgatcgttgt gcgtataagt caaactgatt ttccctggtt
     1681 caaatacctt ttctactaaa aattcttttc tcaattgttc cgttgaataa tgacggatat
     1741 cttctggact gtgtgtataa cgtgtttcca tttcttgcat tttcttctac tccttctatc
     1801 gaatgatttt tccagagccg catgctaaaa attgtgcgac ttcttcttga ctaaattggt
     1861 tgcagtcccc atggatcgta tgcttcaagg cagaagctgc cgtagcaaaa tcaatgattt
     1921 cttgcggaga catattggat aaaatcccat ggagcacgcc acctgcaaaa gcatctccgc
     1981 cacctactcg atccacgatt ggggtgattc tatggacttg ggattccaca tattcatggt
     2041 tcatccacaa tgtccccttc aattcatttt cacttgctga atgaacggta cgcttggtcg
     2101 aataaaacac ctgaatattc gggaactttt cctgcatttt ttgataataa taaattagag
     2161 gttgttcttc tgcttctggc gctttctcga tacctaacaa ataaagagca tccatttttc
     2221 cagctgagca gatatctact aaaggtaaaa gctgatggat tacttcgctg gcttcttgct
     2281 gtgtccataa ttttccacga tagttgatat cgaagctgat caggcagcca gctttttttg
     2341 cagcttctat cacctgtttc gtcatttttt gccatttttt agacaaagct ggggtgattc
     2401 ctgaaacatg aaatatatct attccttgga ataactcctc tagcgaccat tccaaatgat
     2461 ccatttcagc aaaacttgat ccggcacgat catagatcac tgaggcggcg cgttcgccac
     2521 taccagtttc catataataa gtacctagtc ttgatccacc agataatacc tgtttcgtat
     2581 ctactccata acattgcaag tgctttttga ctgcttttcc caatgcgtta tcaggtactt
     2641 ttgtagcaaa aatcgcttca tgtccgtaat tagctaaaga aattgctacg tttgcttccc
     2701 ctccgccata atgggcagcg aatcgttcac ttgaatcgat acgggttccc tgctctgtgg
     2761 acaatcgcaa catgatttct ccgagtgtca ctacttttcc cataagcagc tacctcttga
     2821 tttctttcat ttttgctgca tactgttgcg cgacttccgt tactttgtca aaatctcctg
     2881 tagctgcggg tgctaaaagg ttcccaccta ctccgactgt tacgacacca gcatcgaacc
     2941 actctttcat attgtccaga ctcacaccgc cagttggcat gatattgact tgaggcatcg
     3001 gcgccttgaa ggcagaaatg atacttggtc cataagcgct tccaggaaat agtttgacga
     3061 tatctacccc gcttttcagc gctgttttga tctcggtaat agtcatacat cctggtaagt
     3121 aaggaatttg atacagattg cacatctctg ccgtttcttg atcaaaggaa gggctaacaa
     3181 tatactctgc gccagctaag atagccaagc gagctgtgac agcgtctaat actgtgcctg
     3241 cgccaatcac tatttctggt tggtctttgt agaatgacaa aagttctttg attacttgat
     3301 ctgcttgagg gactgtaaaa gtcaactcaa taccagttag accacctttg atgattgcgt
     3361 ggcaagcatt caaagcttct tctttgcttt ttccgcgtac caccgcaatc actccggcgt
     3421 ttttcaatcg agataaaata tcaatttttt tcatcttctc cacctatttc ctatttagaa
     3481 attttatttt ataacttgga aatctatacc catattatac ggcagaaaag aaaaattgca
     3541 aacgcttttt tcattatttt tgaattcttt gctcgatttc gctttttgtt tgcttgaggg
     3601 cactgattat ttgttctttt gtctcatctg ttaaacgata tttcggcata cttacactaa
     3661 atgcaccaat gatttgttcg tttttcacga ttgaggctcc tatacaaaaa atatcacgtt
     3721 cgatttcttc atcgtcaaat gcgatgtggg tttcttttac cgttttgatt tcctttttca
     3781 accgtaatgc attggtgatc gtatattctg tgtaagggat caacggatgc ttttcaagat
     3841 aatcagtgta ctgctcttca ctgaattctg ctaatacggc tttgcccatc gcagaattgt
     3901 ataatggtcg ggtgattccg atttttgaag acatgcggat cgtttgatgt tttggatcta
     3961 gtttgttcac gtacaagatc tcattgttgt ccaatacccc taagtggata gtctcatcga
     4021 tcttttgctg cagctgttct aaaaacggta aagtcaactc taccaaatcg atttgttcaa
     4081 tgtttttatt cgcgtagcga ataagctttg cacctaaacg atagtttttc tctgaatttt
     4141 tatttacgta gccgatcatc aacaaagtat ctagtatttt caagactgta gaagaggtca
     4201 ttcccacacc ctttgcgatc gtctgcaaag agacatcttg gttttccgct aaatagtcta
     4261 gtattttaga ggctttgatc aatacagttc cataaggctt tttattttcc atataatatt
     4321 ctcctatttc tttataagaa aaattatagc ggaaatacca tcaatttaaa agagatatcc
     4381 agatataaac taccatttct ctttacaggc aatttaatgt tgaagatccg cttcgttttt
     4441 acatcaaact ttgatataaa gcaatgattt cttctactgt cgtttctctt ggatttcctg
     4501 gtgtgcatac atctcgcaaa gcatcttctg caattgctgg aatatctgct tcttttacac
     4561 ctaattcaga aatggtttct gggattccaa ccgctttgct caaccgatcg atctcaccac
     4621 aagccgcttc tcttacatct tctaaagaca tttcagctgc tcctttaatc cctagaacaa
     4681 gagcgatctc acggtacttt tctccagtat attctttgtt atatttcatg acagttggca
     4741 aaagtgctgc acacgctacg ccatgaggaa tgttgtacca tgcacttaac gggtgagcca
     4801 tcccgtgtac cagtcctaaa ccgacatttg agaagcccat tcccgcaata tactgtccta
     4861 atgccatttt ttctcgccca ttttgatcgc catctacaga agcttccaaa gaatggccga
     4921 tgatttcgat tgcttttaaa tgcagcatat cagtcatttc ccaagcgcct tttgtgataa
     4981 acccttcaat agcatgcgtc atagcatcca tacctgttga tgcagccaat tttttcggca
     5041 ttcccatcat catatcgctg tcgatgaacg cgacgattgg gatatcatga ggatcaacac
     5101 aaacaaattt tcggtgattt acttcatctg tgatgacgta gttgatcgtt acttctgctg
     5161 ctgttccaga agtcgttggt atagctaata taggtaaaca tggatttttc gtatcagcaa
     5221 caccttctaa actaatgacg tctgaaaact ctggattcgt caaaataatc ccaatggctt
     5281 ttgccgtatc gattggcgaa cctccaccga ttgcgatcaa acagtctgcc tctgcctctt
     5341 taacaaaagc cactccatct tttacatttt ggatcgttgg attaggtacg atcccgtcgt
     5401 ataaagcata agcgattgct gctttatcta gaagttctgt tacttttgtt gctataccgt
     5461 gctcgatcaa tcctttgtca gtaatgacag ctgctttgcc gaatcctcgc tgctgaaatt
     5521 cagggacgat cgactcaatc gctccttttc caaaatacga tgtttcattt aaaatcattc
     5581 gattactcat tttctattcc tcctaatttg tattattttt cacaataaaa acgaaagaac
     5641 cccaagcaac cggttgccca gttgcttgtt gctacagttc aaagactggc atcaattccc
     5701 aactgactgg agaggcatct ggatttgtct ccatgatatc ttccatgtac ttccaccatt
     5761 tttgattgat agatgtattt gccatttttt cccataactt ttcatcttcg atcactaagt
     5821 aaccaaataa caaacttgta ctcggatcaa gatagatcga atagtcgatg accccgtgtt
     5881 cacgaagtgc tgtacgcatt tctggccaaa gttcatcatg tctttttttg tattcttctt
     5941 gtttttctgg gtaaactttc atgcaaaaag cttttttcac catgtcagac acctgctttc
     6001 gtatgaactt cctccaaata acctgctttt ggagtgacac caaacgcatc tgctaaatgc
     6061 cacaggtttt cgtccgtgat tgtttgcaag attggtcctt gcgctttgac gtacgtatag
     6121 acttctgctg ccttttctgc tgtctcgatc aaaccaaaga cttcatccat gtcttttcct
     6181 gacccgtaga ttccatgttg tggccataaa accaatcgag tttctttcat tttttcagct
     6241 gttgcttccc caatctcatt tgttcccgga accatccacg gaatgatgga aattccttct
     6301 ggaaaaacaa ctaagcattc cgtacacatt tgccatagcg tacgactaaa ggaacgttcg
     6361 tctaattcat gcgtaaaact catcgctaat agatgactag catggcaatg cataacgatc
     6421 cgattatctg ggtctacttc taaacgggcg atatgactca tgaaatgact tggcaactcg
     6481 cttgtaggaa ggcattcgtt ttccagcccc cacaaaagtt ccagtgtttt gccatcttca
     6541 gcaactcgaa cgattccaag attctcggca ggttcgctcg ctacattttt aaaatatctt
     6601 cctgaaccag ttacaataaa atagcatcct gctaaacggc tggcatcaaa aatcatcgag
     6661 atgcggcgga tcactttttc aggatccaag aacggtgtga tctcttcttc ttttagtaaa
     6721 taagaaatat tcccgccatt tctttcatcc catcccaagc gataaagatt cgacgtcgtt
     6781 tcgatcattt ctttcacata aggcgcttgt aaaatatcta tttttttcaa tatagccaca
     6841 ctcctatttt cttaattcca acacgtcttt ttgatattcc tggacttctt ccagccaatc
     6901 caaaccaact ggaacttgat ttttgtaaca gaaataattc catacatcgg catacgggaa
     6961 atctttcaat tcttccgtat aagccattct tgaagtaaag tcaaaagcca gctccatttc
     7021 tttcaatcgc tcaactggtt ccagcatagc tttcagcagt gctttttgtg tatttctcgt
     7081 accgatgacc caagcagcga tacggttgat cgttgcatca aagaaatcca gaccgatatt
     7141 tgttttttcc aacaattcgt tacggactaa ttctttagcg atttcctgca attcatcatc
     7201 catcaaaacc acatggtctg aatcccaacg cactggacgg gaaacatgca acatgattcc
     7261 tttgctgaat aaagctaatg aagataattt attggaaatc acttctgttg gatgaaaatg
     7321 tccagcatct agacaaacaa gtttgtcacg agtcaacccg taacccatat aaaattcatg
     7381 ggaaccgact gtataagctt cagcgcctaa accaaatagt ttgctttcta ctgcatcttg
     7441 tacataccgt tcatctaact cttctgtaaa aatttcatcg agtgattcca ttaaacgttc
     7501 ccgtggggta aaacgatcaa tcggattatc tttcatccca tcaggtaccc aaaagttatt
     7561 gatacttgtt tgcccagttt ctttcccaaa gtactccgcg attttgcggc ttcttttccc
     7621 gtgttcgatc cagtattcac gaacttcttt atctggatga gccaatgtaa agccgtcttt
     7681 catcattgga tgcgaaaaga aagtcggatt gaagtcaaga ccgatttctt ctttttttgc
     7741 ccactctacc catttttcaa aatgtttcgg ctcaatttca tttagatcga cagattcttc
     7801 tgtatccaaa tagatagcat gaaggttcaa tttgtgtttg cccggtatca acgaataagc
     7861 cttctccaga tcttgtctaa gctcttcagg tgttcgtgcg gctcctggaa aattccctgt
     7921 cgccatgatt ccaccggtca attcgccatc cggtgtcaag aaacctttga catcatctcc
     7981 ttgccagcaa tgcatagaaa ttttgatgtc ctgtatcttt tctagtacag catctgtatc
     8041 tacaccgata gttgcatatt tttcttttgc ttgttcgtaa tttctttcaa tcgtgttcat
     8101 acgattactc ctttgatttt attcacgtac cattccatcg tgttttgctt attttcatct
     8161 gggtaaaaag tttcacatgg aaacgactgt ttgattacat ttcttgcttg ttctatattc
     8221 gaaaactgac ctgtactgag catttgcatg gcaacattcc cgattgctgt ggcttcacta
     8281 ggtcctgctt ctacaatgat tccggcataa tctgctgtca attgattcag tagacgatta
     8341 ttcgatccgc cccctacgat gtgcagcttt tccaatttcg ttccagttaa gtgttctact
     8401 ttgatcagct cttgtgcgta acaaagagca agattatcat acacacaacg agcgatagct
     8461 cccgatgaga cagggactgg ctgctctgtt tcaaaacagt attgctgaat ctcttctatc
     8521 atatttgggg gattcaaaaa tcgagggtca ttgatttcca tcacttgctg cagcggtttt
     8581 tcttttgcag caagctctgc caattccgca taactgtact cgtactcttg cattcgggca
     8641 acttcctgga tcaaccacat ccccatgatg tttttcaaaa aacgcaccgt gttatgggca
     8701 ccccattcat tcgtataatt ttcagaaaaa gcattgcgag aaacattggc gatctttgtt
     8761 tcaatcccta aaagcgacca tgtcccactg ctgatataac cccaacgttc tccttgacct
     8821 ggcgttccta atacagctga cgccgtatca tgacttgcta ctgtgataaa ggtcacatct
     8881 ggcaaatcat attttgaaaa ttgttctttt tgcagatctc ctagtatcgt tcccggctct
     8941 gtcaatggtg gaaataattc cttcgagaca ccgatttttt caagaagttc tatttcccat
     9001 tcttttgtcc ctgcattcag cagctgcata gtagatgcat tagttttctc cgtcaccatg
     9061 ttaccagtaa agacataccc taaataatca ggtatcagta acaatttatg tgcttttgcc
     9121 aaattttctt tttcttcagc aaacaattgg aacaaggtat tgaaaggctg gatctgaatc
     9181 cctgtctgct catacaactt atctagagaa tagatttcag aaaactgttc tactgctcca
     9241 ttggtacgct tgtcccgata agcaatcgga tcatttatcc gatccccttg ttcatcaatc
     9301 agacagtaat cgactgccca tgtatcgatc cccgcaaaaa ggcgatcaat ccctgtctgc
     9361 tttaattttt caaatccaat caaaatctct ttgataagat aatcgatctt ccagcgatcg
     9421 tgaccgtctt tgttccgaaa gccgtttttg aaccggtgta cttcttccaa gatcaaagaa
     9481 ccttttgcat ccctcgtact tttcattagt cgtccgcttg atgcaccgat atcgatggca
     9541 acaaatgttg gattcatttc tccacctctt ttactttatt gttgattagc actttattaa
     9601 taaagcgtta tcatttattg acaatgctat cataatacag aatcttatat tttgcttcac
     9661 actattttgg tatataattg cattatcttg acaagttggg agtgtttaca tggattactg
     9721 ggaaaaagcc aaccactcat ggtcggaaga ctcaaaaaga gtgatcttga cgcctacaca
     9781 aagaagcagg aatttatttt tttatatcca agaaatcggt tacttcaaag caccaatccc
     9841 ttactatact gaacgagcac atttaccttc ttacttgata aagtttactt tgtctggcaa
     9901 aggttcgctt acatataatg ataatcagca acagctaaaa gctggagact tattttttat
     9961 tgactgccaa gaatatcagc gttatcaaac gatcagcgaa gaaccatggg aaatggattg
    10021 gatccatttg aatggtcaga acgtccaatc attttatcag gagttcacaa aagacggcca
    10081 taacaccttc cattcaacag gagatccatc agaaaacaag atccaccatt tgatcacaga
    10141 attgatccac atgcaacaag gcacgaatgc ccgtaccgat ttccagtcct ctgtagctat
    10201 ccacgagttg ctgaatgaac tgattttgca aaagtatcag ctagatttcg aagaagagga
    10261 tattcccgcc tacgtttaca aactgaagca atacttagac gaacatttca aagaaacgat
    10321 tacacttgat caattagaac aacaattctt attgaataaa tatcagctga gcaaagattt
    10381 ttccaaattt atcggttctc caccaatcga ttatttgatc agcaaaaaac tttcttacgc
    10441 taaagacctt cttcggtata cagaatttac ggttcgaatg atttccgaag aaatagggat
    10501 tgagaatttt gcttacttta gccgcctgtt caaagcaaaa acaggactat cgccgagaga
    10561 ctttcgtaaa ttcagctgat tcatataata tgtacgtcat tttttcaaaa tattttgaaa
    10621 tatatagata aaaataaaat aaccgcagtt tctgcttcta tgtaaacaac agcagctact
    10681 gcggttattt tttagtgatc attctcattg ttcatcttca aaatgttcat aatgaaccaa
    10741 ctgtttctgt gtatcacgtt tcaaaaattc tttaggcgtt atgccgaact ctctcttgaa
    10801 tgctttcaga aaatgcggat aagaagaaaa accactttta ctatatacag cactagagct
    10861 gcggtattct cgcaacaagt gcttggcata gatcagcttt ttcttcatta catactgatg
    10921 aaacgtaaat ccagtgtact ttttaaattc tcgtgtgata tggtatttgc tgacaaaaaa
    10981 ctgcttttcc atttcctcta aagaaagcgg atgagataaa ttttttgaga tatattgtaa
    11041 catttgttcc acacgctcat taggaactac agcattctgt tcttgcgcac tctcttcttt
    11101 ttgtacaact tgattgagaa aaatcaagta ttctaccaga gcttgttcat attttatgtc
    11161 ttcaccgtaa atttttttat caggaggatg gtcgataaat gataattttt gcttcaatac
    11221 ttcctgttct atttgcaata cacgactcct cttctctccc attggttgaa aacaagccga
    11281 tagattagac catggcgtgg aacgactttc tagaaaagaa ggggtgacaa agatatagac
    11341 acgctcgaat acatctgaag attggcggac gatacgatgc aaatcattgg aatggatgag
    11401 cagcacactt cctgctttga tcgtaaattg tcgtccgttc aaataaaaag tcgcttctcc
    11461 ctttaatgta gcatggatct catagaaatc atgatgatga tagatcgttt tattttggct
    11521 gacgacatct ttgacatgat agatttcata ctgatcagaa accatcgtat tgacttgttc
    11581 accgctgatt ttcttttgga gcatgtgccg cacctccttt tgttcactta tgcacaattt
    11641 tattatacca cgttttttgt aatcaaaaag agctgctttt atatactctt ataaaaaaga
    11701 agagacgtgg catcttctag ccccgccccc tccattctaa atattagtta accaacgtct
    11761 tctttacatt attcaagaag acttcttcca taacgaatcc catcatcttt tgtttcttca
    11821 agaaccacat acaggtacgg acgattcttc atgatgattt ctttgatttt tgtgtactcg
    11881 atcacaccgt ctcccaaatt taccggcacg attttttcct gttcgacacg aaaatctttc
    11941 aaatgaaccg cacatatctt ttcaccaaaa cgttcaaaag cttcttctac caattggact
    12001 tgttcttgat aatcactact tgtgatcaaa ttggtcggat ctaaaatgat tcctagatag
    12061 tccgaatcta ctgcttggat cagctgctct acccttgcta aagaatacac cggatgattc
    12121 aaacctggtt ctatccccac catcatttgg tatttttctc cagcttttac caagcgacgg
    12181 ataacggaca cagcttcagc aaatgcttca tctgtgaaat tttcttccgt atattggatt
    12241 tccggcaaaa cacatccagt ttccgaagca accatcgacg caccaaagga agaagcatag
    12301 cgaagatact gctcgaactt tgtcagcaac tcttgtcgta tcgttaaatc tggatgaatc
    12361 atattgatat agcaacttaa aattcctacg gtcacttctt gcttttctaa aactcgtttg
    12421 acataatttc ccatcccaga attgatctca tttgcgccag aaggtatttc aggaaacgaa
    12481 agacctaagg cgagctgcag tgtatgaatc ccttgttctt ttgttttttc tgcaagatct
    12541 tctatcgttt ggacttcgga aagatcatgt cctctaattg taatgttcaa cataactatt
    12601 ctcctaactc agcatattgg gtagccacat gacgatttgc gggaagtaag taatcaaaaa
    12661 caagacgact aagataaccc cataaaaagg aagaagcggt ttcagcattg cctctgcttt
    12721 tacgcctcct acacttgcac cgacatatag tcctgtacct actggcggcg tgatggagcc
    12781 tacacacaga ttcatgattg aaaacaaccc gtaatgtaca ggatcaaccc ctacacttgt
    12841 gacgattggt aaaaatattg gtgtaaaaat caagatagca ggcgccacat ccataaacat
    12901 acccaccagt aataacacaa gattgactaa taacagaata ataaatttat tatccgttac
    12961 gcccataatc aacgaactaa ttgcctgagg aataccggta aacgccatgg cgaaagacat
    13021 catggaagaa gtagccaata agaacatgat cgtccctgac attgctactg attgaaacaa
    13081 catattaggt atatctttta gttttaccgt tttatagtaa aacatagcaa tcaacaggga
    13141 gtaaatgaca gctatcgctg aagcttctac tgctgtaaat atccccgtca agataccacc
    13201 gataatgatg acaatcaata gaaggctagg aatcgcctct tttattattt ttccagcatg
    13261 agccatctgt cctttttcga caacagggta tttattcttt ttagcaacga tgaatgctac
    13321 tagcatgatt cctagcgccc acaaagcgcc tacgagataa cctcccataa acaaagcaga
    13381 gatcgaagca ccaccagcaa caagtgaata catgataaaa gcagtacttg gaggaatgac
    13441 catacctgtc ggagctgacg cgatattgac cgctgtcgca aacttccggt catatccttc
    13501 ttccacttgc tgagggatca acactccgcc aatcgcggta gaagcggcaa tggccgagct
    13561 agagatggaa ccaaataaag cattccctaa cacattcgta tgagccaaag cccccggcac
    13621 gcgcccgacg aacaacatcg caaaatccac tagtttctta gctatccctc cattattcat
    13681 gataatgccc gagagaacga aaaacggaat agcgatcagc gaaaaactat tgatacttcc
    13741 caccattttt tgagctgaac taaaagcaga aacatcaaac ggtataacta acaataaagt
    13801 catcatcgat gagaatgcaa tacttatagc aatcggcatc cctaatacaa gcaacacaac
    13861 aaatacaaaa aataacacta atccggcttc tattgccatt ttattcctcc atttttatat
    13921 tttttcttga attgctggct tgttgcttaa tgtatcgatt agattgatca ggctatagat
    13981 aatgatgagt acccccgata caggtactga cagataaaca tatcccatag gaatacttaa
    14041 agaaggcgag atctgcccca ttgtcaatgt gacagcattc catccgccat acaccatgat
    14101 catcgcagca aataccagaa ataaactttg aacaacaact tctaaaattt tacttttttt
    14161 gccagttaat ttttcactta aaaccgttac ggctaaatgt gctttttgtc ccacaacata
    14221 cgcggaagac aacatggcaa accagacaag accgaatcga acaagctctt ccgtgaccgt
    14281 atttggattt cctaaaaccg ttctggaaaa tacttgccat aaaacaacag cgaccatccc
    14341 aacaagcaaa acagctccca ggatctctaa taccttgttt aaaatcattt tcatcacagc
    14401 tacgctcctt gctcttggat cttttgataa aggtctttgt aggtaggatc gtttttgaat
    14461 atatcatgaa gtggggcaac tgcctctcga aacggtgtat tatctacatc attgaattgg
    14521 actccatgtt cttcttgtgc taaagctttt tcttcttcaa ttgcttttgc aaaagcttca
    14581 atttcaaaaa ccgttgattc tttcgctgct tcttcaatgg ctttttcctg ctcatcagtt
    14641 agctgttctt tgatggcatc attcatgatg atgatatctg gcacacgtgt atgctcatca
    14701 taggaatagt atttagccac accaccatgt ccagctgtat acaagacaaa ttcattgttt
    14761 tctgatccgt tgatcaaatt ggattgaaga gacgtgtaca cttcatcact tcccataggt
    14821 acgggcgaac cgcctaaaag ctctaccatt ttgatagcgg tttcgctttg catcacacgg
    14881 atcttctttc ccttcaaatc ttccggcgta tggatcggac cgtctaccat ataaaagctg
    14941 cgctgaccag aatcataata ggtcaatccg gtaaatccta aatttttggt cgattggtag
    15001 attggctcca ttatttcttc attatccatc accttaaaga aatgttcttc atcattgaat
    15061 agataaggaa ctgaaaaaat cgaataatct ttagagaaac tttccaacgc tgaggcactt
    15121 acttttgtga aatctactgc tcctgactgt gtcaattcga tcagttcacg ttctccaccc
    15181 agttgtccat ctgggaaata ctggatctgt acggaaccat ctgttttttc ttttactaaa
    15241 cgcccaaatt cattcattgc atcaattact ggctggctgt tgcttgcata agcaaagcgc
    15301 aaggtaacta tctcatttac atctgcatct gcgacagttg ccacactaga attatttccg
    15361 cagccgctta gacctagcag acctaggcta agcgaacttg ctgcaaacag cagtgatgtt
    15421 tttttcatat gggtttcctt tcttttaaca ataagagacg agcaattctg tcaaacaaag
    15481 caccgttaac gactgtccat aaggcattgc tgtgattccg atattccgat aaaaatctaa
    15541 actgtccccc attcctgtcc cgattgaaac gttttgaact tctccttttt catcgatttg
    15601 ttcaagcaat ccttggatag cacgataagc gacttcttta tattcttgtg gtaaataacg
    15661 tttatggacc gctttcaaaa taccgtaagc aaatcctgca gttgcagaag attctacgta
    15721 agaagaagga tcatccaaca acgtatgcca taaaccgctt tcagactgat aagtttttaa
    15781 tgcacgcact tgtgcttcaa gtgtttcgat caataatttg cgcaatgcat cttctttcga
    15841 taattctaag atttcaatga tctctggaat agcaatcgtc aaccagcagt ttccacgagc
    15901 ccaaaatgct tcggcatagt tatgatttcc ttcaaacgtc cagccgtgat accacaatcc
    15961 tgttcgttta tccatcaagt atttgatatg gatcataaac tggtaacgag cttcttctaa
    16021 atattctggg cgattcaaca gtttcccgat ttttgccaaa ggaagcactg tcatcatcaa
    16081 tgtatcgtcc cacaactgat tcttattttc cggtccatat gtggcatgct gtaacccgtc
    16141 ttcatttgtc cgaggcatgt cattcatgac ccattctgcc cattgttcta aataaggcaa
    16201 atagcgtgaa tctttcgtgt cttcatacaa gtaagccata gtcaatagcg gtgccattgt
    16261 attgacgttt ttgggcggag cgccttcttc catacgatcc tcaaaccatt cattgaccac
    16321 ttgataagcg cgaggatttt ttgtcatctg gtaattttta taaataccat atagaccgac
    16381 accttgtggc caattccaca ctgtccagct tttgtcatct actttcagtc catcaaagtc
    16441 caacaaaaat tcaccattat cgtctttgat cgttgtcagg ttttcaacga gcaggtcaat
    16501 tttttctttc actaattctt taggtacaaa aatctcttct ttaataatca tctttacgcc
    16561 acctttttaa acgctttcat tttatatcct taatatagca gtaataccgt ccactataaa
    16621 tatcgctttt tgaacaaaaa ctgtctaaaa ttgacctaaa tgttaaataa caaaagtaac
    16681 tttcagttac ttggaaatta aaaaaagaac ttggagaaac aacgttttcc aagttctttt
    16741 tcatctattt tcttatcttt tttctacgct ttcttttgct tatccgttgt aagcatcaat
    16801 gatgatctgt ttcaattcag agatcaatgg ttctttcgga ttagctgtcg tacattggtc
    16861 ttcgtaagct aattcagcca tacggtctac ggttgtatct agtgtttctt gtgtgactcc
    16921 ttgagctttt agactcatgt tgatgccgac agattttcct aattcataaa cagccgttgc
    16981 taaagcttcg actaattcct ctgttgtttc gcctttcaga cctaagaatt ttgcgatatc
    17041 tgcgtaatct gtatctgcac ggaaatagtc atatttaggg aacatcgcat gtttttgtgg
    17101 atcttttgca ttatagcgga taatatgcgg taaaagaatc gcatttgtcc gtccatgagg
    17161 gatcccgtat tccccgccga ttttatgtgc gactgagtga caaataccta ggaatgcgtt
    17221 agcaaacgcc ataccagcca ttgtagaagc gttgtgcatt ttttcacgtg attccatatc
    17281 aggtgttttt actgattttt ctaaatagtc aaagactaac ttgattgctt gtaggctcaa
    17341 tccacgtgta taatctgaag ccatgactga aacataggat tcgattgcat gtgttaacac
    17401 atccatcccg gtatctgctg tgacagatgc tggaactgac atgacgaatt gaggatcgac
    17461 gattgcgaca tctggcgtca atgcataatc tgctaacgga tatttcacat gtgtttcact
    17521 gtcagtgatg accgcaaatg gcgttacttc agaaccagtc cctgatgttg tcgggataca
    17581 tacgaattgt gttttttctg gtttgtcgat cttatatgtc cgtttacgga tatccaagaa
    17641 tttttgtttt gcaccaaaga aagatgtgtc tgggtgttca tagaacatcc acattccctt
    17701 agctgcgtcc attgcagaac cgcctccaag agcgattact gtatctggct tgaagtctgc
    17761 catcagtttc gttcctgcgt atacggtatt tgtcgatggg ttcggttcaa catctgagaa
    17821 gacttcgatc ttcacatcat ttttacgtcg tgccaatact tcacgaactg tatcgcagta
    17881 accgaattgg accataccag ggtcacaaac gatcatgaca cgttcaacgt tttccatttt
    17941 ctctaagtac aatagagagt tcttttcaaa gaagattttt ggcggtaatt tgaaccattg
    18001 catgttattt ctccgtttcg ctacagtttt gacattgatt aagtttacag cagagacgtt
    18061 acgagaaaca gagttcttac cataagaacc gcatcccaaa gtcaatgacg gaatcatttc
    18121 gttatagata tcaccgatgc cgccttctgc agatggtgta ttcactaaaa tacgacaagc
    18181 tttcattcga agaccgaatt tgacatgcaa ctcttcgttt tctgaatgga taactgctgt
    18241 atgtcctaat cctccaagat tcaacatacc ttcacacaaa tcaaacgcat ggtccgtgtt
    18301 gttagctttg atcatggcaa gaactggaga aagtttttct cttgatagcg gataatctgg
    18361 gcctacgcct tccaattcag caatcagcat tttcgttcct tttggtacac tgattcctgc
    18421 caattttgcg atttccatcg cagaatgtcc aacgattgat ggattgaccg catattttcc
    18481 ttcgttcatc actgcatctt ctaatttttg caattcatct ggttttacga tataaacttg
    18541 gtgtgcttgg aattctgctt ttactgctgc atagatttct ttatccacga tcacagcttg
    18601 ttcagaagca caaatcattc cattatcaaa tgttttcgaa acgatcaaat cgttcactgc
    18661 acgtttaatt tttgctgttt tttcaatata agctggtacg ttacctggac ctacacctaa
    18721 agctggtttt cctgtagagt aagcagactt gaccattcca gctccacctg tcgctaagac
    18781 gatcgcgata cctggatggt tcattagcat agaagtcgct tcgatcgaag gatgttcgat
    18841 ccattggata caattttcag gagctccggc agcgatagca gcatcacgta ccactcgtgc
    18901 tgcttctgca gaagattttt gggcacttgg atggaaagca aaaacgattg gatttcttgt
    18961 tttcaacgcg atcattgatt tgaaaatcgt tgtggaagtc ggattcgttg ttggagttac
    19021 tccgcaaacc acaccgactg gttcagcaat ttcaatcaac cctttttgga catcttcatt
    19081 gatcacacca actgttttat catgtttgat attatgccaa atatattcgg acgcatacat
    19141 atttttgatt gctttatctt cgtaaacacc gcggcctgtt tcctctacag ccatcttcgc
    19201 taatggcata tgttgatcca aagctgccat tgccatttca tgcacgatat ggtctacttt
    19261 ttcttgatca aagctttcca tttctttcaa tgctgcattt gctttttctg ccaaatcatc
    19321 aatcattgct tgtacgtcaa ttgtcttcgt tttttctttt tctattactt tagccatcat
    19381 tatcctccta atgggtcatg gttatttgtt aaataattca catgtatatc atacaatatt
    19441 tatttttcta tgtaaacact tttttgtgat ttttttcaca gttattttta aatataaaat
    19501 tgctttattt acaggtgttt gtatagaaaa atatataaag ttatttatta ttatttatat
    19561 gacacacccg attattcaat attgagcaat atatcccatg ctcttatctc tttctttttt
    19621 gaataaaaaa tgaggtagga catctttctg ccctacctcg tctttaaata agctttgata
    19681 cttatttttc ttccttctct tctgtctctt ccagcgtttc tgttgtttca gtttttactt
    19741 caactgtctc agctggttct tctgttgttt caacagtagt cgttgcatca tttgttacga
    19801 cagtccctgg tttgaccgtt ttgattgctg cacgatcgta ctcaaggaag atcccttcgc
    19861 agtctaaaac aactgtccgt ttgtcattgt cgatttctga aacaactcca tgtaatccgc
    19921 cgatcgttac gactgaatca cctggtttca tgctatctaa caagttttga cgttcttgct
    19981 gttgtttctt ttgcgaacgt gacataaaaa accacattgc taatagcgcg ataaacatca
    20041 caagcattgg taatgttccc atttttttca cctcactaat tctgtatcta caaaaaacac
    20101 tttagcagaa aaatgctgat aacactagtt ttttacttaa tttttaaaag attttccttt
    20161 agaagctttt tgcgttttct ttattgaacc cgtattcttc aaaaaaggct tctctaaatt
    20221 caagcaaatt atcatccatg attgcttgac gtacttgttt cattagattc aacaagaagt
    20281 ataaattgtg gtaagaagtc aaacgaatcc caaatgtttc atcacatttg atcaaatggc
    20341 ggatataggc acgtgtatag tttttacatg tataacaatc acatttctca tcaattggac
    20401 ggaaatcatg ggcatatttc gcatttttca ctactagacg gccttgagaa gtcatacatg
    20461 tgccatttcg agcgattcga gtaggcaaga cacagtcaaa catgtctact ccacggataa
    20521 caccatcgat caacgaatca gcagcaccga cacccatcaa gtaacgtggt ttgttttcgg
    20581 ggatcaacgg tgtagtgaat tctaatacac gattcatttc tgatttaggt tccccgacag
    20641 ataacccgcc gattgagtaa ccagggaaat ccatcccgac tagatctttc gcgctttgac
    20701 gacgaagatc ttcaaaccct gctccttgga tgattccaaa taatccttga cggtctggat
    20761 tagcatgagc tttcaatcct cgttctgccc atcgagacgt acgttctact gattttttca
    20821 cgtagtcgta actttcatcg aatggtggac attcgtcaaa actcatcatg atatcagagc
    20881 ccaatttatt ttggatgttg attgcttttt ctggtgataa aaacatacgc gaaccgttca
    20941 agtgattttt gaaatgcacg ccttcttctt cgatattccg catatcactt aatgaaaaaa
    21001 cttgaaagcc gcctgaatct gttaaaatcg gttgatccca gttcataaat ttatgcagtc
    21061 cgccagcttc ttctactaag tcttcaccag ggcgtagcca taaatgatat gtattactta
    21121 aaataacgcc agcacccatt tctttcaact cttctgggga cattgttttt actgtagcta
    21181 atgttcctac tggcatgaac attggtgtgg ggaaagttcc gtgtggcgtg atcaattccc
    21241 ctaaacgcgc gccagtatgt ttttctttct tgattaaacg atagcgaatg gcaggttgcg
    21301 tcattcattt ccctactttc tatataaaat atcttgacaa ctcccaccat cataatcgtt
    21361 tcaagtgctt tttgcaagtt ccctcggctt ccttctactt tatttaatat tcttttttta
    21421 tccttttttt atgaataaca aaaaaaagaa aaacattatg acagaaatat tttttgatac
    21481 atggtatatt ggtgttatta aagaaaagga gggaaaaatc atgcaatctt ctgcagaatt
    21541 aaaacgccaa gcaaaagaga gtctaaaagg acgttgggga caagctgttt tactaaatct
    21601 aatccctaca ttgattggta ttgctactat tcttcttatt atgattccta ttatcttgtt
    21661 tgccaccacc atatatgatg gatcagcgag cgtctcagaa gcgacaactt caggaggcgg
    21721 tagttcagga ggcggtggcg gaattatttc cagcatcatt agcgctttgt tcatgagcgg
    21781 tatttcttgg acttatcttg atattttacg tggacaaaaa gatcagatcg aaccattcaa
    21841 agatgcattt cgtggattca aaggtttgtt tatcggcgga gtgatcagct tagctgtgct
    21901 gatctcgatc tttacaacat tatggggttt gctattagtt attcctggaa tcattaaaag
    21961 ctattcttat tctcaaagct attttattta ctacgatatc gtccaagaaa caggacaaac
    22021 acctaaagta ctggatacga tcactgcaag tcgaaaattg atggatggtt ataaaggaca
    22081 acttttctgg ttagatcttt catttatcgg ctggcatatc ttagcattag caactgctgg
    22141 tattggttat ctatggctca gcccatacat ttctgcaaca aaagcagcat tttatgaaca
    22201 attgccaaaa gatatttaaa agagagtgtg acttgtgacc gagggggtgg caggagaaca
    22261 ccgtttatcg agaggcagta aaagaaacat tcagcccatt agcaaaaagg aggtgtgaca
    22321 acattcatgt cacacctcct ttttgtatag ttccagtaaa aagaaaatca acttagaaac
    22381 agttaatcat tcctcttctt ctgcttccgg taatcgatgg aacttgatca gttcattcac
    22441 cgcgattggt acgatagata aaatccctac caagaaccag tgattcaaac tgatgtgtac
    22501 taggccgaat agttcttgcg taaatggcag caaagcaaca gccgttgtaa tagctaatgc
    22561 cagtaacgcc atttctacca aagctttatt ggtcgctaaa ttgactttga agatcgattg
    22621 gctgctgcgt acattgaaca catgcagaat cgatgaataa gctaagatca agaatgcaac
    22681 agtttgaccg acatgctgac ttgcgtctac ccatgggctg atagtatcga cataactacc
    22741 taaataataa ccaaacaagg ttacgatggt gaagacccct gcatttatgg caattttttg
    22801 caataaacct cgagcaaaga tcccttcatt tttcggaatg ggtggctgat ccatgatgcc
    22861 gtgttccgct ggctctcttc ctaaagcaaa tcctggaagt ccatcagcaa ctacattgac
    22921 aaacagtagt tgcacagctg taaatggtgc tccccatcct aacagcatcg caatcaaaac
    22981 aataaagatc tccgaaatat tacagcttag caaaaagttg atagctttac gaatattctg
    23041 ataaaccgaa cgtccttgac tgacagcgtc tacgatcgtc gcaaagttgt catccgtcaa
    23101 aatcatatct gcggcacttt gcgccacatc tgttcctgtg atccccatgg cacacccaac
    23161 gttacttgct ttcaacgctg gtgcatcatt cacaccatcc ccagtcatcg ctacgactgc
    23221 acccgtacgt tgccaagatt tgacgatccg gatcttgtct tctggcgtta cccgagcata
    23281 gacagagaga gctttgacac gcgcatctaa ttcttcgtct gataattgat gcagttctga
    23341 tcctgaaagt gcttctgacg gatcattcaa gatacctaat tctttcgcta tggcactggc
    23401 agtcaccaca tgatctccag tgatcatgac tgttttgatg ccagcctttt tcgctcgctt
    23461 gattgctcct ttactttctg gacgtggtgg atcgatcatt ccgatcagac caatcaaacg
    23521 taagtctttt tccagtgctt cagaagaaat atcttgcggt tcttcgtcat aagtagcata
    23581 accaacagca atcactctca gtgcccgttt accaaagcga tcattaacga tcgccgcttg
    23641 ttctacatcg cctgaactaa agcgcggagc aagaacatcg aatgctcctt tggtgattga
    23701 gatgtatttt tcgcccattt ggtgaactgt tgtcatcatt tttcgttcag aatcaaaagg
    23761 aagctcgttt actcgtggat atttttcttc taattctgcc tttgtatgat aattctcttc
    23821 aacagccctt acgatggcta cttctgttgg attacctttg ataacaaggt cgtcatcttc
    23881 ttgctcgacc gtcacatctg tacatagtgc agccattttc aatatttcca tcgcgctgtt
    23941 cgtcattgaa tcttcgatat tcgttacttc atcttctttg ctccataccc ggcggacgcg
    24001 catttcattt tgtgtcagcg ttcctgtttt gtctgagcag ataacattag cggttcctag
    24061 cgtttcaact gctggcaact gtcggatgat cgcatgtttc ctcgccatct tctgcacacc
    24121 gtatgcaagt gtcaacgtaa caataacagt caaggtttcc ggtacagctg caacagccaa
    24181 ggaaatcgaa gtcatgaaca tctcaaggag tggttctcct tgcagttcac caatcacaaa
    24241 tactaaagcc gcagccgcta aagcgatcat actgattcgt ttgcctagct gattcaatcg
    24301 gacctgtaaa ggtgtttttt gcatagtatt ttcgttcaaa agatccgcga tcttacccat
    24361 ttctgtagcc atgccaatgg cagtgacgat cgctttccca cgacctgcag caaccgtaca
    24421 tcctttaaat accatattaa gttggtcacc taatgactca tcttcttcag caataaatgc
    24481 tgcatctttt tcaactgctt cactttctcc agtcaacgcc gattcttcta cacgtaattg
    24541 tgatgcttcg atcaaacggg catcggcaga aatagcatca ccggactcta aaacaagaat
    24601 atcacccact accagttgct ctgactcaac agtggtcact ttgccgtctc gtatgacagt
    24661 tgccgtttgt ttattcatat cttgcaagga ttccagtgct ttttctgcgt ttccttcttg
    24721 gacaatcgcc aataccgagt tgatcacaac gatagcgatg atcagcagtc cttcaaataa
    24781 atccccatgt tctgtagcaa atgcggtata aaaggaaatc accgctgcta caagaaggat
    24841 gatcgttgta aaatcggaca agcttcgaaa gaattttttg atcatcgatt ctttcggcgc
    24901 ctcatcgaat ttattcaatc cctgcttttt tcgccgttca tccacttctt gtgaagacaa
    24961 cccagtatct ggatctgctt ctgttacctt ctttacttct tctattgtct gcttgtattc
    25021 ttccatccta ttcctccttt aaaatcttcg tacaaaaaaa ggtacttatt ttactataac
    25081 atcctttttt tatttacttc aaataaaggg cttatcgatt atttgttaag aaagcgtaaa
    25141 atttaaagtg cttatatttg caaacgctac caaaggatgc tattatatag atgtaaggaa
    25201 ggaggatacc atcaaataga cagaagaatt tctcgataga acagtgtaag caaacaaagt
    25261 tgttagaagt acaggtttca cccagacatg cgtgtagagt acaaacctat aaatagtgaa
    25321 tgcgtatgga tgtttggatc acgaagtatc cgaaacaaga agtaatgcga tacgtaacaa
    25381 ttgaataacg taaacgtctg aaaattgaat aggaacaaga gatgtttcaa atgttgaaga
    25441 tgtaacgaaa acaaaatttt tgtttaacat gaagaaattc aacaccgtgc tttgcatgta
    25501 tgatggaaag ttacaatcat ttctgtttat ttgaatcctt ccgaggtaca agaaagccga
    25561 gcttatcgag agctcggctt tttctttgtc ataaaatctt tgtaaagctt ttttgttatt
    25621 caaaactagc ggcttttcat aaccttattt cacgaacatc gcatctccaa aactaaagaa
    25681 acgatagcgc tcttcaatcg catgctggta agcagataaa gtcaattctc ttcctgcaaa
    25741 ggcactaact aacatgacta aagtcgattt tggcaaatgg aaattagttg agaaagcttc
    25801 taccactttg aattcatagc caggcgtaat gaaaatatca gtccatccgc tgtctgcttt
    25861 gatttctcca ttaaatttcg ttccaatcgt ttctaatgtt cgaattgaag ttgttccgac
    25921 agccacgatt ttcccgccat ttttacgtac ttggttcaat cgctcagccg cttcttccgt
    25981 caaacggtag aattcactat gcatatggtg ttcttcaatt ttatctacgc tgacaggtcg
    26041 gaatgtacct aaccctacat gtagtgtcag atagactaat tcaacaccct ttgcttcgat
    26101 ctcatcaagt aattctttcg taaaatgcaa tccagctgtt ggcgctgcag cagaaccatt
    26161 ttctttcgca tagacagttt gatagcgatc tgggtcttcc agacgttctt tgatatatgg
    26221 aggcaatggc atttctccca atgattcaag aatctctaga aaaattcctt catactcaaa
    26281 gtcaatgatc cgtccgccgt gttccaattc ttctttcact actgcttgca atctgccatc
    26341 accaaaagag attcttgtcc caactttggc acgtttcgca ggtttgatca atgtctccca
    26401 cgtatctcct tgtgtattcg ttagaagaag gacttctaaa tgcgcaccag tatctggttt
    26461 ttctccatat aaacgagcag gcagaactcg tgtattattc ataactagcg catcaccagg
    26521 ctgtaactct tcaatgattt catggaaatg tttatcttcc atctctccag ttttccgatc
    26581 caaaacaagt aaacgagaat gatcgcggtc ttttaatggt gtttgtgcga ttaattcttc
    26641 cggcaagtca aaatcaaaat cttctgttgt taacatatcg tcactcactt tctatcatgt
    26701 gcttcatcat tctatcatgt ttttcgttct gttggcaaaa tcagcacttt ttcacttcta
    26761 ttttttgttt tcctaaataa aaaaactacc ctatttgtat tttttcattg ttttaggcat
    26821 actagtaata gatagttctt cattgaaaat agaaaaagag gtggcaccat gattgaattt
    26881 caaaatgtgt caaaaattta taaaggtgga aaagtcgctg tagaggacgt caatctttca
    26941 tttgaaaagg gtgagttcat ttgttttatc ggtacgagcg gaagcggaaa aacgacgacg
    27001 atgcggatga tcaaccgaat gactgatcca acacaaggga aaattttgat tgatggaaaa
    27061 tccatccaag aaattgatcc agtggaattg cgacgtcaga tcggctatgt tatccaaagt
    27121 attggattga tgcctcacat gacgatccgt gaaaatatca ctcttgtcca aaaattgttg
    27181 aaagtcagtc aagaagaacg gaataaaaca gctgaaaaaa tgattgatct tgtggaattg
    27241 ccccgtgaga tgttagatcg ctacccacat gaattatctg gtggtcagca gcagcgtatt
    27301 ggagtcgttc gtgcccttgc agcgaatcaa gatatcatct tgatggacga gccattcggt
    27361 gcgcttgatc caatcactcg tgattccttg caagaccttg tcaaagattt acaagagcgt
    27421 ttgggaaaaa cgatcgtatt tgtaacccat gacatggatg aagcgattaa actagcaagc
    27481 cgtatcgcca tcatgagtga aggccgtgtg atccaatttg atacaccaga aaatatttta
    27541 cgtcatcctg caaacgattt cgtagaagag ttgattggag aagatcgcct actacaagcc
    27601 aagccaaatg cgacaagagt cggcgaagtt atgctaaata cagcaatcac gattacaccg
    27661 gaaaaatcat tacaagaagc aatcaaactg atgagggaaa aacgtgtaga tacgttgtta
    27721 gttaccgata attcgaatgt attaaaagga tttatcgatg tagaaacgtt gaataaaaaa
    27781 cgaggaaaag tatccagtgt cggcgacatt ttgaataaac atgtttttta cgtaaaagaa
    27841 tccgcctatc ttcgtgatac cttgcaacgc attttaaaac gcgggctgaa atacgtgccg
    27901 gtcgttgatg aacagaacaa agtcgtaggt atcctgactc gtgcatcatt agtggatatc
    27961 gtctacgatg tgatttgggg agaagatccc gcaactactg atgttgcaga gtcagctact
    28021 cctgaagaat ctaaggaggt ctgacctatg cagcagtttt ttcatcagca cggttcagaa
    28081 attctctcaa aaggttttga acatctttat atttcaggac ttgctttgat cattggtatc
    28141 atcattgctg taccgcttgg tgtcttactg acacgttttc caaaagctgc cacgattgtg
    28201 attggcttaa ccagtgcctt gcagacaatc ccttctcttg ctttattggc attgatgatc
    28261 ccgctatttg gcgtaggtaa attacctgcg attatcgcac tctttattta ttcattattg
    28321 ccgattttac gtaatacgta cattgggatg aaaaatgtcg attggaatta tcgggatgtg
    28381 gcaaaaggca tggggatgac tgagttccaa tccatttttt ccgttgaatt gcccattgct
    28441 atgccaacga tcatggctgg tattcgttta gctgccgttt acgtgattgc atgggctaca
    28501 cttgcctctt atatcggcgc tggtggttta ggcgatttga tttttagtgg actgaataat
    28561 taccaaccag atctcatttt ggcaggtacg atccctgtaa caattttagc actattggct
    28621 gattggcttc taggtctctt ggaacaccgg ctgacaccga tcgcacttag agaggagaat
    28681 gaagaatgaa acgtatacta aaaatgacca tggttctttt ctctcttctt atacttgcga
    28741 gttgttcctt ccctggtctt gccagcaata cagatgaaga caccatttcg atcacaggtg
    28801 gaatcacttc agaagcacag atcttagcaa gtctagttgc cggaatggtt gaacattata
    28861 cagataaaaa taccgcaatc atcaacaatc tggctactac aactatcaac catcaagcga
    28921 tgatgaacgg agatgcttca atttcagcgg ctcgctacac aggaacagat ttaacgacta
    28981 cattgaacct tcctcctgaa aaagatccga aaaaagcgtt tgctaccgtg aaagatgaat
    29041 ttgagaaaag atacggtcaa acgtggttcc cgtcctatag ttttgaaaat acgtatgtct
    29101 ttcttgttcg aaaagacacc gcacaaaaat accatctatc taaagtcagc gatctgaaaa
    29161 atgtagcgga tgaattagta gctggtgtag atacttcttg gatcaatcgt aaaggagacg
    29221 gttatgacgg cttccaagaa acttatggct tctccttcaa ttcgatatta cctatgcaga
    29281 ttggacttgt ttatgacgca gtcgaagcag gaaaaatgga tattgttctt ggctactcta
    29341 cggatggacg gatcgccagt tatgatctag tcatgttgga agatgatcgt caattcttcc
    29401 caccatatga tgctgctcca gttgtagaca acaagatatt agctgatacg cctcatttaa
    29461 aagaagcctt aaataagtta ggtcatacca tcagtacgga aaaaatgcag gaattgaact
    29521 acgaagcaga taataatcta gtggaaccat cagtagtagc acaacgtttc ttacaagaaa
    29581 accactattt tgaagggaag tgaagcaatt ggataaaatg aatgtctttc aacaattttt
    29641 ctattatttc caggaaaatg gctcctatat ctttgcacaa tttatccgtc acttcctgat
    29701 ttctatctat ggtgtcctct ttgcagcagt tgtcgggatt ccggttggga tcatgatttc
    29761 taggagacgt aaattagcaa actgggtgat tcgtttggcg aatatcatcc agacgatccc
    29821 ttctctagcc atgatctcca ttttaatcat tggattaggc ctgggagtca atgtcgtgat
    29881 tgttactgta tttttgtatt ccctcttacc gatcatcaag aatacgtata ccgggatgat
    29941 ccaagtagac aaaaacatcc ttgatgtcgg caaaggcatg gggatgactg ctagacaacg
    30001 actattcatg gtagagttac cactctctgt ttctgttatc atggcaggca taagaaacgc
    30061 gttagttgtt gccatcggga taaccgcgat cggtgcattc gtcggtgctg gtggtcttgg
    30121 agatatcatt atccgaggaa ccaatgcaac agagggcaca tcgattattt tagcaggtgc
    30181 attgccaact gcattaatgg cgatcatcac ggactggctt ttaggtattt tggaaagacg
    30241 gctagatcca gccagccgta catcacgctg atgttattgt aaaaaacaaa agcttctgcg
    30301 accatttgtt ggtcgcaaag gcttttttag ttctgtcatt tttaaggcaa taatccactc
    30361 tgattcttcc ctccttatgg gcaaagagtt gcttttctta gctatttatc cattccgtat
    30421 actccaactt catactgcca acgggttcat atctgcatcc accgactaag tttttttctt
    30481 atccgctaag gcattttgcc aatccatttt cccatcactc gtcatggaat tcataccaca
    30541 tgatctctaa atactcgtct gcttgttctt tgaattgggc atcaattctt acatcctttg
    30601 gcgtggcttt catttaagcc ttttccatca gtcctcgatt gttcgatgcc ttcagctgca
    30661 tcatcaaaac tggtgactgc cgtatcggta acttcgatca tcttttatac aatcgggaac
    30721 ttgccatcct catccttggc taaaaacata tctagccatt ccagcttctc gccatgggag
    30781 gtttgcggtt cctaaaaccg gtacacgatt cttatggact gcatccgtcg caactagact
    30841 tggcgatacg atgatccttc accagaagag cacccccgta aaccaattga tcgatatatt
    30901 gccaataaga aaagacattg gcgtaaaaga tatcgatccc tcgtgatgca ttgccgttga
    30961 tactgctatt catggccgaa agcgccacga ctttaacttc ttccgtttga gtgacattca
    31021 tgttcggcaa tgtcgctttg gatacccgct ctgctaaagg aacgacactg gtattgtatt
    31081 tcgtatctgt atcttttcca aaagaccatg ccaacgaatc ctctgggaac caataagacg
    31141 actccggttg attgtccatt gcttttttca acatactttt ggctgtttct cgataaacga
    31201 catttccaat tgtcttcgcc tcactttggc gataatcgat ggtcgttgcc actgccaaca
    31261 ctaacaacga tgctccaatt ttactgattt tccttgtcac acttcttcct ccttgtttta
    31321 cataaacccg tcaacattcc attcctaaac tcaaacaatg acccttcaaa ggtggagata
    31381 taggaacaaa ttaaagaaat catgcaataa atccaagaag gttggtttta gaacaaaaaa
    31441 agagtctcct ttttggggag actctttgtt aactatctaa aaaggttggc tcttctcact
    31501 tcactcataa tgtgtccagg cagaataaat ttctacaact ttattttcct catcaacttt
    31561 gtaaaccact cgatgctgtc tattcagcct gcgtgagtat ctgccttcat gtgtaggtct
    31621 cagcttttca aaagactgcg tgggcatata tggatcttcc ttcaatgtct gaatcacttc
    31681 ttcaaattgt ttctttaaat tcgtttgctt gatttttctt aaatccactt tcgcagagtt
    31741 tttgattgcg actgtatagt tactcatcaa agagcttccc aatcaatatc atcgatattc
    31801 gtaaagctac tgtcgtcttt ttcgcggtct cgtactttat ctaaagtacc tgtttgctca
    31861 agaaaaaggg tttcttgaat cgctctccag tcttccagcc caatcaatac agcattgttt
    31921 ccactacgat cactaataat ctcgatttca gtatgatttt catttacctc tttcaataac
    31981 tgataaaaat ttttacgagc agtgctagga ttcatcgttg tattagccat tgtctctcct
    32041 cctttttctg atataattat agcgtacttg attaagtacg tcaaaaaaat acaataaagc
    32101 acttaaattc agcaaacttt tcctcttttt tacatagaga aaaagacccc tttttaggga
    32161 ggatctttgt ccacgctcac ttcttactcc tttacgacta gcggtagcca aacgtaaagt
    32221 aattggtaac aacgtatcat ctttagcaaa ggtcgaatcc aaagcctgtg agtctatgca
    32281 acaacaccaa tacacgaagg ttcctcgttg cagtgtgact tgattgatat cttgaataac
    32341 ctgaggatac gcacgaaaga tttgtaacgg ttattcaaaa ctgattttgg ccgtcaagtc
    32401 ttctactgcc tcaaaaatga ttgcctcttt cgtctcctgt cattcatgtt cactatcgat
    32461 ttgatacttg cttagaccgt tgggtttgtg aatcaccaat taaaaatggc actgagttat
    32521 ggtaacaaaa aatggtcact tgacgaggct gagattccta cttatgaaga cacatggcac
    32581 ttaagagtcg aggtaaagga agaagctgaa aatataggag gctgtacatt atttggcaaa
    32641 ggattcggaa attatgatca agacatcaaa atcaaaatgt tttacagcta aataggaaga
    32701 ataataacat ttcatacgct gttcccatct ttaatggctt atagagggca cctttagctg
    32761 agaataagac aaaacagacc ctctagcttc aattaagagc tagagggtct gtttttgatt
    32821 ttaaaacttg gtttatttct tcaaatggta gctataggtg ctgacaacga tattttcacg
    32881 ccaagacaat cgcaatctta accgcaaact tgtttggtta tggagaatat tctgccagcg
    32941 tctgtttggt acaaattgag gaatcaacac agtagttgta tagttttgtt tcgctgcatt
    33001 tttacttacg atatctacat aacggataat tggattttca atcgagcgat aagaagagtg
    33061 gacgattgaa aaacggacat ctgggaaatg ctttttaaat tctgcttcga tttctttttc
    33121 tttttcgaca tcttcgtcta gcgaaacatg catcgcaacg acataatcac cgatcgaacg
    33181 tgcgtaattc aacgcaccga tatttacccg tgtcacattc ccgactaata caagaacggt
    33241 attcccgtca taatcatgta gttttgcatc attttctaaa cgaagctgtt ctgctacttt
    33301 tttataatga tcatggatct tataaaaaat gaacataacg attggcataa tgatgaagaa
    33361 aggccaaatg tcccctaacc gatagacaaa caaaatcgca atgattgcat atgagatgaa
    33421 cgcacccgta atattggcaa tcgatttgct taaccatctt tttccttctt ttttccattt
    33481 gacgaccatc cctgtttgag ataaagcaaa tggaatgaac acgccgatag agtataacgg
    33541 aatcaagcgt tctgttgagc catggaaaat aaacagcaat acgatcgaac ctagcgctag
    33601 tgtgataatc ccattggaat agcctagtcg atccccacga tcttgataca tgtgaggcat
    33661 gaatttatct tttgccagat tgtatgcaag aactggaaaa gcagaaaaac cggtgttagc
    33721 agcaactgct aaaatcagcg ctgtagcaaa ttgaaggacg taatacaaaa taccatgtcc
    33781 aaagacagct ttaccaattt gagacaaaac agtgacttct ttttcaggaa cgatcccata
    33841 ccaatagttg ataaatgtga tccccacgaa gaagaaacct aagatcaatg ccatcatcgt
    33901 caatgtagca gcggcatttt ttgctcttgg cttcttaaag aatggtacag cattactaat
    33961 cgcctccacc ccagttaaag aggaagaacc agaagaaaat gctcgtaaaa tcaaagcgat
    34021 agaaacaccc ggcacagccg ctcctggaag tgcagtagct tgcaatggca cagcacctgt
    34081 cacgatatta tataaaccaa caacgatcag taacgagatc acaaggataa atgtgtacac
    34141 cggaaataat aggaacgatg cagattccct cagcccacga agattcagca tcatcagtag
    34201 caaaacgatt gtcacagaaa tagcgacttg atgaccgtag agtgctggca ccgctgatgt
    34261 gatcgcttca gcacctgctg agacagatac tgctactgtc aacatgtagt cgatcaataa
    34321 agagccaccg gaaatcaagc cagcattctt tccaagattc tcactgctga cgacatatgc
    34381 tcccccgcca tgaggataag catggatgat ttgacgatat gatagcgtta atgaaatcaa
    34441 taaaataata acaaaagcgg caatgggtag cgaataccag atggctgcag cagacaaagc
    34501 gactaaaacg acaacgattt gttccgtacc atatgcaata gatgataacg catcagacga
    34561 caataatgcc aaagcagcaa atcgggttaa tttgtgctca tcattttcag cagattttaa
    34621 aggcttacct actaacaacc tttttaagta atccaatttc taaactcctt tacacacaat
    34681 tttacttcaa gttttatagt cgaaaattta tagtaaacaa gatgttatag tacgctcact
    34741 gaccttaaaa gtcaataaac tttaagaaaa taattggaaa aaaacagaaa aatatcaagc
    34801 gctttttcaa acgctttaat acagcaaaaa tctaacattt tttatgggct ttttctttga
    34861 attctataat aaaaggatag aacttgactt agaaaatcaa gttctatcct ttttgatatc
    34921 ttaacttttg gaagagagat gtaaggctgc tttctaccca tcattcttac tactcgaagc
    34981 atagcgcagt tgtcacaacc tcttgataaa cggtgtttaa aagcttgcat ctgcggtaat
    35041 aagcccaacc aaattaaaaa cataagaagc tgtttttatt tggtcgttct tattacttga
    35101 tgcagagcag cttttttaca acctcttggt acacggtgtt caatcagctg accctcggta
    35161 ttagctcaaa aaaacggcaa aatatgagga actatttttc catttttttc tctaatactc
    35221 aggtcaaaac actgatttca caacctcttt ttttaatgaa aaatatggct ctcatgcgcc
    35281 gcttctttga atttcgtcat tttttcttcg atgaacggat agattgccgt tcctacgatt
    35341 ccaaagacaa caaacaaacc gatcatgatc cagattgctt tcgtagcatt tggccaataa
    35401 attcctcctg cagattcccg taacaagttt accgcatgag taaatggcaa gaacggattg
    35461 atcatttgga agaatttccc tgagacttgg atcggatagt tcccgcctcc gccagagatc
    35521 gacagtacta agatgataat agcgatccct ttaccgacat tatcgaataa tgcagccaag
    35581 acatagacga tcatcatgaa cgctaaggcg atcaagacag caaatgacac gctgtagacc
    35641 ggattttgga catctactcc tagtaagaaa atattcccta atgtaacgat caagctttgc
    35701 gcaatcgcca ttgtcaaaaa tgtcagcata cgagcaacga attgttctcg tttcgtaaaa
    35761 ttgtttcggt ctttctttcc taaatagtat tctgtcgtag caacacttga aagaagaaca
    35821 gcgccgaccc acagacatag tgcagtataa aacggggtgc tagctgaacc gttatttgcg
    35881 attggataaa gcgcattggt ttgtagctca acaggttgtg taaagaagtc actttctttt
    35941 gttgcgtcta gtttcaataa tttgatgact tcgcctagat cgacttcttg ttcgcctttt
    36001 cggatcgcgt ctgctgcttt ttggatacca gctttgatat ttggccagtc attgttgatc
    36061 aagtccgcag cagcgttcac agctgtttcg acttctggca ttttttcatt tactgttgtc
    36121 aatgtaccgg tgatttcatt ttttagtgct ggccaatcat tttggataaa atcagcggcc
    36181 aatcctaatt tttgctgaat gatcggtaat tcattgttgt ataggtctgc cccttcattg
    36241 atgccattga cgatggtatc catatttcca ttcagcattg tattggcatc atggatttct
    36301 tgtccaattg caggcatttc tttttgatat ttttctaaaa ttgccactgc attcgttaca
    36361 gttgctttcg ttgagctgag aagcgaatca aagtcgatct ggtccgcttt gctcagtgcg
    36421 ccttgtgcag tcccaatcgt atcgatgact tggtctagta gagaagtgac agtggaactg
    36481 atttgacctg tattgatacc agcaatgatg ccattgatat tattaacaac ggcatcaatt
    36541 tgatctagca attcatcaat agccttcgtg tcttcatttt gaacagctgt gttcaaagca
    36601 gataggcggt tttgcagatt gcttagcaag ggttttaatt gatttagctg atcaataatt
    36661 ggctgtaatt tcgtatttcc agcacttgtt tgcaatttag tcaggaactc gaccagttta
    36721 tcgattgcat tttgttgttg agatattccg tcaataaagc cgttcaatac attgctgatg
    36781 tttttctttt catcatcagt cagcttacca tcttcaatag ctgttcttac agtatctatt
    36841 aacgaacctg tcgttgttgc cacttgtcca attgacttca atgtaacatc tacactgttt
    36901 gtgatgcttg gtatcgcatc tttcagctga gaggcacctg attttgtttg gtttgctaga
    36961 tcacttgcct gattttctaa atttttcaca tctggcaaga tatcttgtac ttgttggatg
    37021 atcgtcaagc cttgttttgc ttcatcgatt ccttggttca ttgtctcttg gatcgaagca
    37081 aaatcgccgt cgatctctgc tagttgctta ccggcatttt ggatctctgg gattttttct
    37141 tgcaaatcaa ggatgatttt tgcttgatct ttcaactcag gcattttgtc attcaatgca
    37201 acgacttttt cacccatctc atctacttta gggatgtaat ccacgaattc atttgcttta
    37261 ttcagttttt ccttgatttc aggtagttga ctttgtaatt cgaggacttg ttttgtgtag
    37321 ccgtcgatcg tgtccaaatt ttcatctgtt gataaaatca tatctttaac tttattgata
    37381 cttactaggt tcgtatcgat gtcgtaacct atctcattga atactttcaa taaagtcgaa
    37441 ctggctgttt tgataaattc atttgtgatt tgcgattgga tcgaacttgc tcctttatcg
    37501 gtgattttcg gtgcaatcgc attgattttt tcatttaccg tatattcgat ttttggtttc
    37561 ttgatatcac cactagtaaa actcagcaga tcttctgaga aatcctttgg caagtaaata
    37621 cctgcgtaat actttccgga acggactccg tcttctaatt gttcttttga atcaacgaat
    37681 tgccatccta attgtttatt tttatgaagc gattcgatga cttgctcccc aatggccact
    37741 tctttacctt gaaactctgc tggcttgtct gcactgtaaa cagcaattgg cagctctcca
    37801 gtatttccat atggatccca taatgctttg atgttaaacc acgcatatag cgaagggatg
    37861 atcatgatcg cgatgatcag aagtgttgca atcgggtttt tgaaaatccg tttccagtca
    37921 agcaaatata atcgaagcgt atttttgatt gactgcatag ttctccccct tcttcttttt
    37981 tcagctgaat tactttacca tgtatttcat acttttttca atcggctttt ttcaaaaaag
    38041 tcgaattttt ggacatatca cggcaattgt ctcattgtaa tctcttacat attgagaaat
    38101 aattaaggat tacagccttt actttatcat gaaataaaag ggaaagataa ttttatgcca
    38161 aagtttttat ctattatacg tatacgcaaa aaagctaaaa cattttttgt ctttgcccct
    38221 acaaaaatgt ttcagctttt ttcgtttttt attcctgtat ttcttatttt tcgaatgaca
    38281 ggatgatttt cccagcagga ggatgtcctt caactagctg atgtgcttgg atgacatgct
    38341 taagtgaagc agacagattc attgaaataa aaacatgaaa ggctcctttt tggtaggctt
    38401 tgattatgcc agcaaaggct tctgcatcta gatattcctt tcttggaaca aacgattcat
    38461 aaaagccttc ctttttttgc cgcaaatcta gatctgggag gtcatttaat gcaacatacc
    38521 tgccgcctgg tttcatgatc tggatgccgg tttctccttt gatacttcct ttcgtcgcat
    38581 cgattacaag gtctgcctga tcagcaaatt gcagacctgg atttgtttta tcataagcag
    38641 caaatgctga agctcctaat ttttttacct tttcctcatt tttactggat gcactggtta
    38701 agattcggat tcccttttca tggagaagct ggatcagact tgacccgacc gcacctgatg
    38761 ctcctagtat cattacagta tctgtcggct ggatttccgt caaatggttg attagattat
    38821 aagccgtaat tcctggcgtg accattccgg ctgcttcttc ccaactcatt ttatctggaa
    38881 tttttgctac ttttgctgat ggcaacacga cttcttctcc gtaagtcccg ccgactgcat
    38941 ggacagctac tcgatcacct acatgaacag ttgtgacatc tgaaccaatc tctgtcacaa
    39001 taccagcgcc atcattacct ggtacataag ggaatttcaa tgttcgtatc tctttcattt
    39061 ctcctaaacg caaggcaaca tcataaggat tcacactgaa tgcttttatt tctacacgaa
    39121 catgtccaga accgacttct ctgggatgag catcgatttc ttcaaaaaca tcttgtgctt
    39181 ctccgtaacc gttaattgca aatcttcgca tggtcaccat ctcccttttt ctttaagttt
    39241 acgtttatgc ctttattttg acaaaaaaaa tgtcttttcg ttttggcgca tgattcaaaa
    39301 caaaatagtt gtcttttttc gcgtaacgtg ttaaattatt tatctaaaag cgtaaagatt
    39361 acgatttacg ctaataaaaa ataattggag gaatttgttg atggctaaaa aatcaaagat
    39421 tgccaaagca aaaaaacagc aagaaacgat tgaacgctat gctgctttac gccaggaatt
    39481 aaaagcgcaa aaagattacg aaggcttgcg taaacttcct ttagatgctc gtccagaacg
    39541 attgaaaaat cgtgatttaa tcgatggacg ccctcgcgga tacatgcgta aattcgggat
    39601 gtcccgtata aaattccgtg aattagcaca taaaggtttg attccaggag taaaaaaagc
    39661 cagctggtaa tccaagtctg gctgtaatgt aaaggaggag ggcgcatgga ccactccttg
    39721 gatcatcaaa aaagatacgt tcgcttcttc tagcagaaat gctggtacta gaagcagacg
    39781 tatctttttt tacgcacagc tggtcctttt ttatatgtaa aggctgcatg gttacttcgc
    39841 tatatttatt tagtaacagg agtcagtgct tcgataccca cactaatttt caatgctcgg
    39901 tcaacttctg ccataatggg tcgatccaaa tggcagacct tttctttcaa tcttgattta
    39961 tcgatcgttc tgatctgctc caacaggata acggagtctc tttctattcc tgttccagta
    40021 gctttgatcc caatgtgagt cggaagctta ggtttagcca tttttgccgt tatggccgca
    40081 acaatgatcg tcgggctaaa atggttacct agattatttt gaataaccaa aactgggcgt
    40141 gttccgcctt gctccgatcc cacgactgga gaaagatcag caaaataaat atctcctctt
    40201 tttaccatag gatcctcctt attcttgata ttctcttggt atccgctgtc ctaatccgca
    40261 agccacttca tagtggatcg tacctaattg atctgctata tcctgcatag tgatttcttt
    40321 gtctgcattt ttgccgataa gcgtcacttt tgttccgaca ggaaattctt gaggcaatcg
    40381 gatcatcagt tgatccatac atacacgccc aatcgtttca cagtagttcc cttctaccaa
    40441 tagagaaaaa ccctgcatct ttcgtggcca gccatctgca taaccgatcg gtatcgttcc
    40501 gatccactct gcttcaggag tgatatatgt ttctccatag ccgattcctt cacctgctgg
    40561 gagttttttg acttgaatca attcagaaac cagctcaagt gctggctgca atggataaac
    40621 ttccggtagt gcgtgcccag agggattaag tccgtacatt gctactccat aacgaatcat
    40681 attgccgatt gtttcatcat gccataaagc cgttgcacta ttgctgacat gtacatatcg
    40741 aggaagttcg ggaagttttt tcagcacttc tataaagcgt tctttttgca gattccaata
    40801 tgtatcatct gcctgatctg ctgtagaaaa atgggtaaat aaaccttccc attctaatac
    40861 acgactttct ttgatgaatg cagctgcctc ttttacttct tcaggtgtac aaaatccgat
    40921 acgacccatc ccagtgtctg cttttagatg aatcgaaaga ggcgtctcta gcttactttt
    40981 ctctaaaaca gcagctgctg cttgcaacca ttcccgtgta cctgcagtta ctgataaatc
    41041 atgagcaaca gctacagtca gtgcgtcgta aggaaccata ttcaagataa ggatgggctg
    41101 agtaaatcca gcttctctca actcgactcc ttcatctaaa tttgaaacac aaaagcccga
    41161 agctccacct gcaactgctg cctcagctgt ttcaatagct ccatgaccgt atccgttcgc
    41221 ttttactact gcaaacaatt cttttccttg cggaagtctt gcaacttcat ttgctacatt
    41281 ttcagttata gcttttttat gtatcactgc tttcgttggg cggtgccaag cgacaaccat
    41341 cgtttttcct tctttctagt cttccaaaat aatttgtgca aaagctgttt catttgtatg
    41401 agtaatactg acccatacat tgccttcatg aggtgaacgc gtcacaacag gctgaccatt
    41461 ttcatttttt aaaatctcga catcttgaaa ggtaactttt ccgatcccag ttccccaagc
    41521 tttagagaaa gcctctttgc aagcgtaacg cccgcctaaa aattctactt ggcgatgaaa
    41581 aggcaaggac tggaatagtt tcatttcatc agaggtcaag attcgtgcaa tgaattttgg
    41641 tttttcttcg atcagccgag tgatcctagg aagttcgact gcatcgatcc caattccttt
    41701 tatcatatgc ttttctcttt tcaataaatt tagaacactc tcattctacc aaattataac
    41761 cattttgcca caaataagtc cacaaataac aaaaatgaaa gtttctctta aaaaagagaa
    41821 actttcattt tatgtttaat cgttatttga acggattaca aatccgcgtt ttttatcatt
    41881 gtgacgttta ccgccatctt tttggctgtt attatttttg ctataaccgc cttttgattt
    41941 gtttccacga taattaccgc cgtcacgacg attacggttg tttccgccac cacgtttgcc
    42001 atttttattg tatccttttt tctgcattgg caatgggcgt tctggtgtga tcttcactgg
    42061 cactgcatca gctggatctt ttgctgtcgt ttttagcaaa agtgcaacta aatcttgtgc
    42121 agaatattct tctaataatt tatctgctgt ttgcaggtat ttatctagac cattttctgc
    42181 aagttttgtt tcgatttgtt caactgcagc acctaattga cctttgaatg cttctttttc
    42241 ggttggtgga cgtaaagtcg tcatccgttt tttcgtcaag ttttcaatca catgcaagta
    42301 gtccatttca tttggtgtaa cgaaagtcac agacataccg ccttttccgg cacggcctgt
    42361 acgtccgata cggtgaacgt agctttctgg atcttgaggg atatcatagt tgtacacatg
    42421 agtgacacct gaaatatcta atccacgtgc agcaacgtct gtcgctacaa ggatatctaa
    42481 atgaccgctc ttaaatgaac gcaatacgct cattcgtttt tgttgagaca aatcgccatg
    42541 gattccttct gcacggtaac cgcgtgcttc taatccgcgt gccaattcgt ctacacggcg
    42601 ttttgtacgt ccgaagacga ttgttaattc aggtgtttga acatcaaaca agcgagtcat
    42661 gatatcgaat ttttcgtatt cttttgcgcg gacatagtat tgatcgatca agtcagctgt
    42721 catttctttc gctttgatct tcacatgatg tggatttttc atgaatttaa cgccaatatt
    42781 cttgatagct ggcggcatcg ttgctgagaa aagtaatgtt tgtctttgat caggaacttg
    42841 tgaaatgatt ttttcgatat cttccaagaa gcccatattc aacatttcat ctgcttcatc
    42901 caaaactaat gtttgaacgg ttccaagttt caatgtgtgg cggttaatgt ggtcaagcat
    42961 acgtcctggt gtacccacaa cgatatgtgg acgatctttc aagccacgga tctgacggcc
    43021 aatatctgct ccgccgtaaa cggcttgtac acgtactttt ttgtcgcgcc ctaaacgata
    43081 taattcttct tgtgtttgga tagctaattc acgtgttggt gcgataacta aaccttgtaa
    43141 ttcgtgacga tctggatcga ttttttctaa cattggtaat ccaaatgcag ctgttttccc
    43201 tgtacctgtc tgtgcttgtc caataacgtc ttttccagct aatgctagtg gaatcgtttc
    43261 tgcttggata ggcgttgctt cttcaaaacc agcgcgttcg actgatttca acaattctgg
    43321 tgataattct agttctttaa atttcaaatg aatcctccta tatggttgtt aactgaggat
    43381 gtagcttttt tgctaccccg tcgatttgtt cggtcaaagt gtattgtttc tttttgacag
    43441 tggccacgca cgtttttatc cattcttagc ccctgtggca ccaccgaaaa atcactttgc
    43501 gaagtttagg cattagaaaa gccaaacggg tcgcgttcag ctttatcatt attatgacat
    43561 ctggcttcaa caagttgttt ctatggcaaa accagtccaa tttctcttca tctttcggca
    43621 ataggttatt ctaacatagt ttttcgtttt ctgcaagttt acagattttt atttcatttg
    43681 ctgaagttgt tctaccactt caaataagcc catgctgttg ctgcctttta gcataatact
    43741 atctgttgct tcaagatttt gtttgatagc atcaatcaat ttattctttt ctttttcaaa
    43801 atagaacaca ggtagttggg ggtatttttg gttcaattct tcttttagtg catgcatttg
    43861 ttccccataa aggaaaatca tggcgaattt ctcaggatcg atatgttcac tcatttgcgc
    43921 atgcatattt aaagactctt tccctaattc cagcatatct gctaacacag cgattctgcg
    43981 tccttttgtt ggcagatttt taaaagtatc taataccagt cccatggctg ttggatttgc
    44041 attgtagaca tcgctcaaaa tagctgcacc atttcctgcc gttagccatt cggttctgtt
    44101 ttgagtgata gaaacatggg cgagcccttg gcgtatctca ggtatggaca gtccaaagaa
    44161 gcgcccgatc gtatacgcaa tcaaagcatt cgttacatta taacttccag gcagcgggat
    44221 cgtaaatgtt tctccttcta ctacaaaatc ggtttgtgct tttccttttg ctgtcacttc
    44281 cgcatgaaca tcgccatttc caataccgaa tgttgtgact gtttgtacta atgttgccgt
    44341 taaaggtgtc agcaacggtt catctgcggg cacaacgagt aatccgtctg atacaagtcc
    44401 gtcagtgatt tccattttgg ctttagcgat tccttctcgc gacccaagat tttctatgtg
    44461 tgcttcaccg atcattgtga ttgctgcagc ttttggttga gccataagtg aaagttccgt
    44521 gatttcattg gcgtgatcca tgcccatttc caaaacgatc ttttctgtat cttggggcat
    44581 gtgcaaaatc gtgtaaggaa gaccaatatt attgttgtaa tttccttgcg tcttatatgt
    44641 tttgtatttt tcagacaaga cagacgcggt tagatctttc gtggtggttt taccattgct
    44701 tcctgtaatt gcaacgactt ctgcgcctac tttttccaag taataggttg ccaattgctg
    44761 catggctttc aaaggatctg ctacaggaat aactggaaaa ttttttggag cttgttcaac
    44821 aggcaagctc caaaatgaag cagatgctcc gtttgtgatc gcttgctgga taaattcatg
    44881 tccatctcgc gtaccagcaa gaggaacgaa taaacttcct tcggttatct tccggctgtc
    44941 aaattcgaca ttggtaatct ttgtcagtgc agagcattcg ctgcccacgg cttgtgcaat
    45001 ttcttgtatt gttagattca ttgagatctc tcctaaaaaa ggttgtgaaa aaagcgtttg
    45061 gcctaaacgg cgggttcgca tgactctcac ttccaagtaa atttctctat tcgtatttag
    45121 aagctagaat gaacgcggtt acgcaatcac tccagcctct tctttatttc tctttattca
    45181 tttttttcaa aaaaagattg acgctgatgg tatcgattca ttcctaactg gatcagttct
    45241 tcaatcaaat caccgtattt caagcccata ttttcccata agagtgggta catactgaac
    45301 tccgtaaatc ctggcataga gtttaattca ttcaggaata attcattttt atttgtcaaa
    45361 aagaaatcgc accggctcaa tccgcttcca cctaacatcg tgtaagctaa cttcgcgtac
    45421 tcttgcgctt tttgataaac ttcttctggc acttcggctg gaatctgcat ttcgatttta
    45481 ttattgatat attttgcttc ataatcatag aatgctacgt cttttacgac ttcaccaggc
    45541 aaagtcgtcc gaacgtcttc atttcctaat acagcaactt cgatttcgcg cgcttcaatt
    45601 ccttgttcaa cgattgctcg agaatcatac tgataggctg ttgctaaagc attttgcagc
    45661 tcttctcggt tttctgcttt tgtaatgccg acactagaac ccatattcgc cggtttgaca
    45721 aacatcggat aaagcaaaga accttcacat tgatcaaata cttttttagg attttctttc
    45781 cattgattct taagtactgg tacataagga acttgcggca caccagcagc ttgtaaaata
    45841 tacttggtca tgattttatc catggcacat gcactggtca atacgcctgc gccgacataa
    45901 ggcatattca atgtctctaa gaagccttgg atcgttccat cttccccgtt tggcccatgt
    45961 aaaactggaa aaacgatggc tccttcttct ttgatttcgc ccggattgat cacttttcct
    46021 gtaaagcctt cctctgtctg tccacttggg tcccatgaaa gatgcaagac atctttgctg
    46081 gcaggttttt ctgttagtaa tggacctttg acccattgtc cttcttttgt aataaatacg
    46141 agttgaactt ggtaataatt ataataaatg gcatttaaaa ctgaaaatgc ggaaagaatg
    46201 gacacttcat gctctgcgct gcgtccgcca tatagtaaag taatcttcaa aagattgtcc
    46261 tcctgtattc taaatcgttc agtgatttac tctcatattt tagcacaaaa caaaaataaa
    46321 cgaataactt atttataaaa aaacgagcca gcttctaaaa gaacgagcgt catttatttt
    46381 ttgtcagcta gattatttgt cccgtttttt ataaaaagtt atgataaaga aaaggaggga
    46441 tgatgatggc gcaaacaaat ccacgcagcc gcttggcaga aatcattcga gtgttcatca
    46501 attacaatgt agtgccaaac tttgtacagc aaaaaaatcc cgaacaggta aaaaaagcct
    46561 ttgaagaact aggccccacc ttcatcaaga taggacagat gctttctgtt cgagaagatt
    46621 tgctttcttc tgccttcact caaacattca aaacattaca agatagtgta cctagcgaca
    46681 cattttcaac ggtcaaaaag acgatcgaaa cagaactttc tctttcatta tcagatatat
    46741 tcgatgattt ttcaaaatcg ccttttgcct ctgcttctat ggggcaggct catcgtgcca
    46801 agctgaagaa cggtgacgcg gtagtcgtta agatccaaca ccctaacatc gccgaagaga
    46861 tccgacttga tcttcaacta tttgaacgag cgatcccttt gatcaaatac attcctgaaa
    46921 ctagcgtagt tgatctaaaa ggggtactcc aagaagtaaa acgttccttg atcaatgaaa
    46981 tggacttctt aaaagaaagt caaaatggcg aacaattcta tcaaaagaac aatggctgga
    47041 aagagatccg cagccccaag atttatgacg ctttttgttc gaaaaaagtg atcgtgatgg
    47101 aagaaatgtc tggtaaaaac ttgaatcatt taatgaacgc cgaaaacaaa actgaaactt
    47161 ttatcactgg aattcaaaac aagcagctga aacaagaagt tgcaaagctt ttagttgaga
    47221 actttatgaa acaggtgttt gatgatggtt ttttccatgc tgatcctcat ccagggaatc
    47281 tgctattcca tgtactaaca aaagaagaac agacacaagc tagccgaaaa actgaaacag
    47341 tccatgaaaa agagttcggt tcctttgctt ttcgagcctc cacttctgca gaagaccctg
    47401 ttgcgccata taccatcaac tacatcgatt ttggtatgat ggggcatctt tctgcaggac
    47461 ttaggcaaaa actcacacaa gccgttttag cgctgtatac gaaagatgct tatcgaatcg
    47521 aaaaagcggt ccttcgactt tgtcagcaag aaggctcgtt tgatgaaagt cggttccacc
    47581 aagaactgac aagttttctt gaacagtatt atgattctcc tattgatgaa atcaacttgc
    47641 aagaagtatt cacacatgtc gtgacgattt gtcatcaaaa taatctgcag ttcgatcgtg
    47701 atatcacgct tttgctgaaa gcatttggga cattagaagg ggtgatccgc gtcctcgatc
    47761 ctgaagtttc cctcatggaa gtcgcttcgc cttttgctca acattatttt ctcactcatc
    47821 tggatgtaga agatacattg aaacaaagcg gattagactt attggaaggg atgaaggctg
    47881 cgcctaagat ccctcaacag ctccaccatc tattagaaat gtggacttcg ggacaaggaa
    47941 aagtcaattt ggaattgaaa aagcaagaca aattattgag caggatcgaa agtatgatca
    48001 atcggcttgt tttcggtatg attttagctg cattgatcgt agggtcctcc ctgcttgtcc
    48061 aagcagcacc tgtagaaaac gcagaggtcg tttccttatt agggatattt acgtatgcta
    48121 ttgccgcatt cgtcattatt tttttggcaa tcgatgcatt gatccaaatg tataagaaga
    48181 ggaaaaagta gaaaaaggtt gtgacagaaa gaatcagctt caagaaataa gaaggggttt
    48241 tacataaatt gtttctcaaa tttttgtgaa aattcggctt atttttcgaa gaggctactt
    48301 ctgaaacacc gagaataaaa aatgtgaaaa agctgttctg cacccagtaa taagaacaat
    48361 caaaaaggga acatggaaca catttatcct gtttccctgt tccctttttg atgtattcga
    48421 gcataaataa aataccttcg ttacctacta tcttctgtac ttggtaaacc ttagtcaatt
    48481 gcctttttta acgcttgacg aaaagacata tgatctttct ccgtaaaggg ttttggaccc
    48541 tttgtcctta tgccagcttt tcttaacttt ccactatgat aacgttgttc tagaagcgtg
    48601 ccgatattcg cttcgtcaaa ttcttttcca gagtgatgga acactcgcac acccttcggc
    48661 aatacaagtg aagctaaacc ataatcttgc gtgatcaaaa agtcattctt cttaaccata
    48721 ccgacgattt tataatccgc actatcagct ccgcggtcta cgtagacgat ttggacatga
    48781 ttagcgtatt ctttggtcgt ataatggtcc acactggtca cgataaccac gtcaagacca
    48841 taggattctc ctaattttat gacatcttct tttactggag aaccatctcc atcaatgaat
    48901 agcctcattc tttttcgcct tcttccataa atgataaaca gttactaatc cgctcagtaa
    48961 aagaccaaca ttgatccatt ttgccaagat aagcagttgt acactttcta tcggcactga
    49021 ttcatggttc agcgtgatca ataatagatg gattggctct cccatttctt ttgctaaaac
    49081 aaacaaaagc gtcatcaata aaaactggtg gatcacactc cctttatttt gagtagtata
    49141 cttgacaacg atccggcgat ccattggaat agctgtatca gtttgataat attccttatt
    49201 tagccagctg cctgttacta cgtgccagaa actaagcaga aagacaccta tcgcaaaacc
    49261 atttggaatc aagaggacca ataaagaaga actcagtcca agcaattgca tagccaatgg
    49321 agaccatgtt aaacgtttca aaatccatgg tccgactatt tttgctgcaa tcaagcctgc
    49381 tgcataaggc aaatacataa aaatcgaaag tttttctaat ccgtacagta tgccaacata
    49441 aaaactgcta aataaaaaaa ggaaattccc tagcattcca tttagaaaag taaacagatt
    49501 tagccagctt ggcaacttcc attccttctt ctggtgtcct aaaacaaaca cgaacaagat
    49561 gaacagcagc aagaaaccat aaatagcaag atcaaaaagc ctttcatcga ataacaatcg
    49621 ggcatttctc aaaagaaaca ataagccaaa gaatatcaaa aataaaacaa gctctcgcgt
    49681 agctaccaga tttcttttga tgtctttgaa atccagttcg taacgcggat aatgactaac
    49741 cgtatggtag gccatgacgt aaaaaagtgt ataaatagta aagcttgctg caatctgagt
    49801 cggtgcaggc aactcaatcg cttgatacag gagaaatagc cagatagctg caaataagta
    49861 ctttttccca tccatattga taaaaccttg cgtcttttcg tgaaaattga ccgtggtatt
    49921 agcaggtaca agccatgctg cactcagccc tagcaaaaca cttgaaaaat aaaataaagg
    49981 aaaataaaat acgcctaata ttccaagcaa tgaaccagca ccaccaatca gcagagcgat
    50041 catcagcaac gtgtaactat ctagaccaaa tcgtagactg ttgactaaaa atagtccagt
    50101 catccgaaag gcataaaaca gcgtaaatgg caaaatcgtc agccaattat gcgagtctgt
    50161 tagtcccaaa aataaaagat aaggaataaa aataaccgtg ttacttaaga taaagggcgt
    50221 tgtttgtgta aaattacgcc caaatcgttt gagtttttcg aacatgacaa tggctcctta
    50281 aacagtctta taactaatct gctcttcgat tttagcatta aaggggaaat aaaccaattt
    50341 tacagaatat attcttgtaa aaaaaaatac agaaagaagc ataagcttct ttctgcattt
    50401 ttacggtact tgattactca agcagacaag cccttctcca caaaagtctt gcccgacacc
    50461 cctgcatccg gcaggtgata aagatagaaa tcaattatcc tgtgcctcca aaatcaatta
    50521 ggagctctgt aaaccagagt ccttctcgac ccgtcgcata aatttacttt aacacagttc
    50581 ctatgtttat gcgagagctt ttttcatttt ataatcgacc atttgaaatc cttgaccgat
    50641 atctgaaata agttcttctg taatctcaaa tccttcatgc ttataaacct cgattgcttg
    50701 atgattcccc tgattcactc gcaaaaagat ctctctttcc tttgtttgcg cagcaagttc
    50761 ttcataccag cgaaaaactg aagaagtcaa tccttgacca cgtactttat ttagcaaata
    50821 taatttactt aaataaattt ttccatttat ctcttcataa gcagtgtaac cgacagtctt
    50881 ttcttcgctt tttaataaaa agtaggacac accttctgtc agttcttttt gaatctgttt
    50941 ttttgactga taagttttca gcatgtaatc cacttgtttt tgaccaatga tcggcacaaa
    51001 aacttccggc catacttctt gtatgactgc catcagctca tccagttcat tttctgttac
    51061 ttttattttt tccatacacc cacgtccttt tttacattat aaatgacctt gcgcttgatg
    51121 gaataaaaag agcatgatca tgctatacac acccaccgac cacggtttca agaaaatcac
    51181 aatctgcata aattccctaa aagataattt cgtcaaacca gctactagac agatcaagtc
    51241 gtctggcgca aagggaagca gcaaggtaac aactagtact tttttaatat ctttcgtttt
    51301 tcttgtcagc aattcatcaa atttctgata cttttttggc gataaaataa gctggacaaa
    51361 ggctacgcca tagtaacgga caagcaaaaa tccgattgct tccccaatca ctaggccaat
    51421 acaactatat aaaagcccaa atccattgcc aaacatcagc atgcccgcta ctgaggagat
    51481 ccctcccggc aaaataggaa tgatcacttg gatcacttgc aacagaacaa atatcatcac
    51541 tgcatacttg ccaaattgct ggataaacgc ttgcaaagac gtgctcgatc gaaaaatccc
    51601 atgatgataa gcataaagaa tcaacacaaa gaaaaaaaac agaccaataa tgggcatgat
    51661 ctgaagacat ttttgtaaaa ctgatccttt tttagacatc tatattcccc acatcttttt
    51721 tcatttatta aaactgcctc ctt
//
LOCUS       DACGLI010000013        51373 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.014, whole genome shotgun sequence.
ACCESSION   DACGLI010000013 DACGLI010000000
VERSION     DACGLI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.014"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            330..1175
                     /locus_tag="IXT22_000847"
     CDS             330..1175
                     /locus_tag="IXT22_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4862231.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="IXT22_000848"
     CDS             1456..2676
                     /locus_tag="IXT22_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAQ4862232.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="IXT22_000849"
     CDS             2673..5393
                     /locus_tag="IXT22_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4862233.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="IXT22_000850"
     CDS             5377..6321
                     /locus_tag="IXT22_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4862234.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="IXT22_000851"
     CDS             complement(6390..7400)
                     /locus_tag="IXT22_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4862235.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="IXT22_000852"
     CDS             complement(7580..7924)
                     /locus_tag="IXT22_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4862236.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="IXT22_000853"
     CDS             complement(7917..8351)
                     /locus_tag="IXT22_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAQ4862237.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="IXT22_000854"
     CDS             8489..9226
                     /locus_tag="IXT22_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862238.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="IXT22_000855"
     CDS             9219..10430
                     /locus_tag="IXT22_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862239.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10637..11416
                     /locus_tag="IXT22_000856"
     CDS             10637..11416
                     /locus_tag="IXT22_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAQ4862240.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="IXT22_000857"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="IXT22_000857"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAQ4862241.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IXT22_000858"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IXT22_000858"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAQ4862242.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="cpaF"
                     /locus_tag="IXT22_000859"
     CDS             14132..15061
                     /gene="cpaF"
                     /locus_tag="IXT22_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4862243.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="IXT22_000860"
     CDS             15018..16067
                     /locus_tag="IXT22_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAQ4862244.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="IXT22_000861"
     CDS             16064..16342
                     /locus_tag="IXT22_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAQ4862245.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="IXT22_000862"
     CDS             16317..16787
                     /locus_tag="IXT22_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAQ4862246.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="IXT22_000863"
     CDS             16804..17106
                     /locus_tag="IXT22_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862247.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="IXT22_000864"
     CDS             17123..17494
                     /locus_tag="IXT22_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAQ4862248.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="IXT22_000865"
     CDS             17466..17825
                     /locus_tag="IXT22_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862249.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="IXT22_000866"
     CDS             17997..19004
                     /locus_tag="IXT22_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4862250.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="IXT22_000867"
     CDS             19029..20213
                     /locus_tag="IXT22_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAQ4862251.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="IXT22_000868"
     CDS             complement(20650..22233)
                     /locus_tag="IXT22_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4862252.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="IXT22_000869"
     CDS             complement(22811..22954)
                     /locus_tag="IXT22_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAQ4862253.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23176..23655)
                     /locus_tag="IXT22_000870"
     CDS             complement(23176..23655)
                     /locus_tag="IXT22_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4862254.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23728..24012)
                     /locus_tag="IXT22_000871"
     CDS             complement(23728..24012)
                     /locus_tag="IXT22_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862255.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24090..24284)
                     /gene="ssrS"
                     /locus_tag="IXT22_000872"
     ncRNA           complement(24090..24284)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IXT22_000872"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24356..25642)
                     /locus_tag="IXT22_000873"
     CDS             complement(24356..25642)
                     /locus_tag="IXT22_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAQ4862256.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25780..26451
                     /locus_tag="IXT22_000874"
     CDS             25780..26451
                     /locus_tag="IXT22_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAQ4862257.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26417..26905
                     /locus_tag="IXT22_000875"
     CDS             26417..26905
                     /locus_tag="IXT22_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAQ4862258.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26918..27865
                     /gene="prmA"
                     /locus_tag="IXT22_000876"
     CDS             26918..27865
                     /gene="prmA"
                     /locus_tag="IXT22_000876"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAQ4862259.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27866..28630
                     /locus_tag="IXT22_000877"
     CDS             27866..28630
                     /locus_tag="IXT22_000877"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAQ4862260.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28863..31076
                     /locus_tag="IXT22_000878"
     CDS             28863..31076
                     /locus_tag="IXT22_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAQ4862261.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31087..31533
                     /locus_tag="IXT22_000879"
     CDS             31087..31533
                     /locus_tag="IXT22_000879"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAQ4862262.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31704..32963
                     /locus_tag="IXT22_000880"
     CDS             31704..32963
                     /locus_tag="IXT22_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAQ4862263.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33052..33999)
                     /locus_tag="IXT22_000881"
     CDS             complement(33052..33999)
                     /locus_tag="IXT22_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4862264.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34393..35685
                     /locus_tag="IXT22_000882"
     CDS             34393..35685
                     /locus_tag="IXT22_000882"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAQ4862265.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35700..37469
                     /gene="aspS"
                     /locus_tag="IXT22_000883"
     CDS             35700..37469
                     /gene="aspS"
                     /locus_tag="IXT22_000883"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAQ4862266.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37578..38453
                     /locus_tag="IXT22_000884"
     CDS             37578..38453
                     /locus_tag="IXT22_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4862267.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38719..40602
                     /locus_tag="IXT22_000885"
     CDS             38719..40602
                     /locus_tag="IXT22_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4862268.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQISNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40677..40961)
                     /locus_tag="IXT22_000886"
     CDS             complement(40677..40961)
                     /locus_tag="IXT22_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4862269.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40951..41685)
                     /locus_tag="IXT22_000887"
     CDS             complement(40951..41685)
                     /locus_tag="IXT22_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAQ4862270.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41814..42437
                     /locus_tag="IXT22_000888"
     CDS             41814..42437
                     /locus_tag="IXT22_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAQ4862271.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42629..43750
                     /locus_tag="IXT22_000889"
     CDS             42629..43750
                     /locus_tag="IXT22_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAQ4862272.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43757..46885
                     /locus_tag="IXT22_000890"
     CDS             43757..46885
                     /locus_tag="IXT22_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAQ4862273.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKAEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTALVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46904..50098
                     /locus_tag="IXT22_000891"
     CDS             46904..50098
                     /locus_tag="IXT22_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4862274.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYAEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKSKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50244..50951)
                     /locus_tag="IXT22_000892"
     CDS             complement(50244..50951)
                     /locus_tag="IXT22_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4862275.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16823 a         8961 c        10653 g        14936 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc ttgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatctcaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggctt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg aaactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccctggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttat
    23041 tttacttgaa ctcattgact gttttccctt tattttaaac attataaaga ccgatgagtg
    23101 cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa aaaaacctgc cgatagttgg
    23161 caggtcgtct acgtgttaag ctttggtgtg gtctttagct ggcaattggt tttctaaatc
    23221 agttcggaca acaagcacat cgcaagctgc gtttctaata acatattcag aaacagaacc
    23281 aataaataaa cgttctacag cattcaatcc tgtggctcct aacataatca aatctacttg
    23341 attatcttct gggatttctc tggcaataat ttgttttggt gagccatatt ctacgacaga
    23401 ggttacatta ttcaagccag ctttcttcgc attgctttca taatctgcca atgtttgctt
    23461 tgccatttca gtagcttgtt ctgcaagcat tccatcaaag gatgaaacgg tttggaaaga
    23521 acgtgtgtca atgacatgtg ctaatagaag ttctccgtta tttcggatag ctacattgac
    23581 cgccttttta aaagctaatt cagcttcatc agaaccatct acggcaacca tgattttttt
    23641 gtattgttgt aacataagca ttcactcctc aagtcaatcg tattgtactc ttttattgta
    23701 gaacacttta gggaaaaaga gaattattta ctgctttggt tcagcaattt tttttgcaaa
    23761 tcggatactg aaggtggcag aaacaataat tacgatcagt aaaaagacca aggcaataaa
    23821 gcgttgattg aaaaaagctg ttaaaatacc cattacgcct aaaacagcat atgcagcacc
    23881 gtaaaattgt aggaatcctt gatttttatc atttttgttg atcaatacaa aaaagatatc
    23941 ctgtttatta aataaataat agctaacgaa taataatact aaagtggcga taatcattaa
    24001 aatcctaatc atgaacaaat cctccaaaat aagcaacaaa tagaaaaagc aatttgccaa
    24061 gagcaaattg ctttattctt taaaagatgg taatctccgt taatgccgtt gtttgtcctg
    24121 tagtattgat cccgcgaatt caagcaggtg ggtcccatgg tcgtagcttc gaactaccaa
    24181 atgataaggc atgttaccag cagtgacaca agacgggtcc caagatatca ataaaaatgt
    24241 tcggtcaaca cacaaagagg acaattcgaa catcacagat ttcccacctc tatagtagca
    24301 tatgaattta aaaagagcaa tgagagagct cgcagaaaca gaaccgtttt cttgtctagt
    24361 tttttggagg atgctttttc cactctttta tacggtaata ctgttgaccc agagcctgtt
    24421 catatttccc tgtatctttt ggctgataat actgagcatt cttcagttta tctggtaaat
    24481 attgctgatt gacccaagcc tgatcaaaat gatgaggata ctgataaccc acgccacggt
    24541 tgagtgattt cgcacctttg taatggctat ctctcaaatg atcaggaaca tctccagctt
    24601 tgccctctcg aatatcagca agtgctgcat ctaatgccat gtaggcagaa ttggattttg
    24661 gcgacaagca aagatcgacg acgacgtctg ctagtgggat acgtgcctca ggcaatccca
    24721 atttttcagc agctaataca gcgttcactg tacgagccgc agcagcagga ttacctaaac
    24781 ctatatcttc ataaccgata accatcagac gccggcaaat acttgccaga tcacctgcct
    24841 caactaaacg ggcgagataa tgaagtgcag catccacatc acttccacga atcgattttt
    24901 gaaaagccga aataacgtca taatgagcat ctccattttt gtcatgggta agagcttttc
    24961 tttggacaca ttcttcaatg atcgacagtg taagatgaat ccttccttct ttatctgaag
    25021 gagtcgatag tgtagccagt tccagcccat tcaatgcact ccgcaaatcg ccgttcgttg
    25081 cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat tgcttgttgt ccaaggccgc
    25141 gttctttatc ccttaaagca tgttcgactg ccaactggat gtcttgttct gttaatggtt
    25201 tgacttcaaa gatctgtgta cggctgcgga tcgctggatt gatggtaata taaggattct
    25261 cagtagtcgc tccgatcaag atgattcggc cactttctaa atgaggaagc agaaaatcct
    25321 gttttgtttt atctaatcgg tgtacttcat ccaataagag gatcactgta ccactcattt
    25381 ttgcttcttc cgctacaact tgtagatcct tttttgaatc tgtagcggcg tttagcatgc
    25441 gaaatgcata attagtagag ccggcgatcg cacttgcgat actcgttttt ccagtaccag
    25501 gaggtccata tagaatcatg gaagagagca tgcgagcatc gaccatgcgg cgtatgattt
    25561 ttccttcccc gactagatgc tgctgaccaa cgacttcatc gatcgttcga ggtctcatgc
    25621 gataagccaa tggctgttgc ataggatttt cctccttctt gtttttacgt cccttaatta
    25681 tatcatattt agcaagatgc ctagaaagaa cagccttctg ttgttttgtt ttcatagctt
    25741 atccaactaa tattgtgtat gataaagtag gtgagaaaaa tgacggataa acaaaagata
    25801 gatgaatttt tttggaataa aacgacgcca gaagtggcac gggatttatt ggggatgtat
    25861 ttggagcatg acacaccaga aggaagatta gctggatata ttgtagacgc ggaagcatac
    25921 ctaggtccag aagacgaggc cgcccatagc tatggtttaa gaagaacacc gcgtgtgcgg
    25981 gcaatgtatg aaaaaccagg tacgatctac ctttacacga tgcatactca tcggattttg
    26041 aacatcatta ctcagccaga agggattcct caaggagtaa tgatacgtgc aatcgaaccc
    26101 gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa aaactggtcc agatatcagc
    26161 aacggtccgg gaaaattagt ggaagcatta gcaattcctc aagaacttta tggtcagtct
    26221 atagcagata gttcgttacg cttagttttt gagaaaaaaa agacaccaaa aaagatcaat
    26281 gctttgccta gaatcggtat cccaaacaaa ggtgtatgga cagaaaagcc gttgcgtttt
    26341 gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa accaaatcga gaaagattgg
    26401 ggttggagga aagaaaatga aaaagaagga tctattaaca tatttagatg aaataattga
    26461 aaaacaagtg acagactatg atgtagcttt agattgggat acaaaaaatc atacgatcga
    26521 gatcgttgtt cgcttgtttg cagaaaataa agcacaattt gagattgatg atgcagaagg
    26581 gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc gtacttcttt ttaatcctca
    26641 gaaatctgtt tttgatgaac gcaattatct agcagtaatc ccttatgaag gaaaaaaagg
    26701 gttggcaaaa tcagtagctg attctttagt ggaatatcta aatgaagtat tagctcaagg
    26761 gcaaagcgat ttgcttgatt ttttggatga agacgatgac gaagctgtat tcgagcttca
    26821 ctgggataat caacaactag cagaattagt agaagtaaaa cagcaaaatg aagcagatac
    26881 ttatttaccg tacccaagtt attaaggagt gacagatatg aaatggaatg aagtaaaagt
    26941 agaaactgaa agtgaagcag tcgaagcagt tgctaatatt ttgatggagg caggggcgag
    27001 tggtgtcgcg attgaagatt ctttagatgt tgaacatttt cagtcggatc aatatggtga
    27061 gattttagat aaaaatgatt ttacatcgct gaaagaaggc gcactagtca tggcttattt
    27121 tccggaaacg actttcttac cggaaatctt gccttttatc aaagatcgta tcacacaatt
    27181 acctgagttt ggtctagcta ttggaaaaaa taaagtaaca gttagtgaag tagaggaaag
    27241 caactgggca acagcctgga agaaatacta tcatccggtg cgtattacgc gaatgctgac
    27301 ggttgcgcca agctgggaaa actaccagac agaagatcct ctagaaaaaa ttatcacact
    27361 agatcctggt atggcatttg gcacaggcac tcatcccacg acttccttga cattgacagc
    27421 actagaaaca gtcttgcgtg gtggtgaaac attgctagat gtgggaactg ggtcgggcgt
    27481 gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc tatgcctttg atttagacga
    27541 agtagccgtt cgttcggcga aagaaaatat ggatatgaat gaaatagcca aagatgtcca
    27601 tgtatcagct aacgatcttt tgacaggaat cgagattgaa agtgatgtaa tcgttgcgaa
    27661 cattttagca gatatcatct tattgatgat cccagatgct tggcgtttac tgaagcaaac
    27721 aggcacgctg atcgtttcag gaatcattga agagaagaag caaatggttc tggatgccat
    27781 gttagaacaa gggtttatcg tggatcaaat tttccagcaa aaagactggt atgcaattat
    27841 tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt ttaaaagaat catatgaatc
    27901 aaaagactat tttgttttag aaggggaaaa ctatcaccac attgtacggg ttatgaggat
    27961 ggaacccgag gatgaagttt ttttggcatt caatgatcaa atagccattg ttgcagaaat
    28021 cacggagatt actgaagagg ctgtttatct gaaagaaatt aaaaaagaag aaaatcaaaa
    28081 ggaactgcca agttcgatta ccatagcgag tggctatcct aaaggggaaa agctggattg
    28141 gatcgttcag aaatccactg aattaggagc gcaagctttt cttggtttcc cggcatcagc
    28201 ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga caacaacggc ttgaaaagat
    28261 tgctcaagag gcagcggaac aatcccatcg gcagatcgtg ccatcagtag agttattgga
    28321 aacgaaacaa gatttatttg agcggctaga tgattatgac gtggtcttgg ttgcttatga
    28381 ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa attcttagtg aaacaaaacc
    28441 agatagtcga atcttagctg tctttggacc agaaggtgga ttatcccgcg atgaagtcga
    28501 ttattttgta gaacacaaag ggatactttg tggattagga ccaagaatcc ttcgtacaga
    28561 aacagcacct ctttatttat taagtgctgc tagctatcaa tgggaattaa tgaatccttc
    28621 tttcagctaa cgttcttcat taataaaaga gtatcgacag aaagaattga aaaaatagtc
    28681 aacaatttgt ataatagaaa caattattta tacaatggat acgaaaaatc gtttgaaaaa
    28741 gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac tgcacggatt ttgggacaat
    28801 tatcaaacag atatttgtcc cgattcccgt tttaccgaaa aaagaaaggg ggatcgattc
    28861 ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat aaagctcgtt agtcaataca
    28921 tgggtcccga acatgtagca tttgttgaga aagcatgcga atacgcgact gctgcacatg
    28981 acggacagtt tagaaaatca ggcgaaccct acattattca tcctatccaa gtcgcaggta
    29041 tattagcaga tttaaaaatg gatccccata cagtggctac aggcttctta catgatgttg
    29101 ttgaagatac agaaatcact ttagaagatc tgagagaaga atttggcgat gacgttgcta
    29161 tgttagtgga cggcgtaacc aaattaggga aaataaaata taaatcccac gaagagcagc
    29221 tagcagaaaa ccaccgaaag atgctgctag caatggctca agatttacga gttatcatgg
    29281 tcaaattagc tgatagacta cataacatgc gtacgttgaa gcacctgcga gaagataagc
    29341 aaagaaggat cgctcaggaa actttagaaa tctatgcgcc tcttgcacat cgtctaggga
    29401 tcagccggat caaatgggaa ttagaagata cagcacttcg ttatctaaat ccaaaacagt
    29461 attaccgtat cgtccacttg atgcagacga agagagaaga acgtgaaaaa tacgtaagtg
    29521 gtactgttga agatattcga atagcgacag aagagctggg gatttttgca gaaatctatg
    29581 gacggccaaa acacatttat tcaatctatc gtaaaatgaa agatcagaaa aagcagttca
    29641 acgaaattta tgacttgcta gctattcgag tgatcgtaga ttcaatcaag gattgttatg
    29701 ctgtattagg agcaatccac acaaaatgga aaccaatgcc cggcagattt aaggattata
    29761 ttgccatgcc aaaagctaat atgtaccaat ctttgcatac taccgtgatc ggtccggcag
    29821 gaaatccggt agaaattcaa atccgaacac aggaaatgca tgaaatcgct gaattcgggg
    29881 ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa agtagaacca gatggtatga
    29941 cgaaacaatt aagctggttc catgagatac tcgaacttca agacgaaagc tatgatgctt
    30001 ctgaatttat ggaaggcgta aaaggagata tctttagtga taaagtctac gtcttcacac
    30061 caaaaggaga cgttactgag ttaccaaaag gatccggacc attggacttt gcatacagta
    30121 tccatacaga tatcggtaac aaaaccactg gtgcaaaagt aaatggcaaa atggtgcagc
    30181 ttgattacaa attgaaaaac ggagatatca ttgagatcat gacttctcca aattcatttg
    30241 gcccaagtcg cgactggttg aaattagttg ctactagcaa agcaagaaat aagatcaaac
    30301 gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa aggccacgaa tccgtggtca
    30361 aatgtattac agatctagga tttacgccta aagatatttt gacgaagaac aaactgcaag
    30421 aagcactcga tcgttttaat tatcaaacag aagatgatct ctatgcagct gtagggtatg
    30481 gagaagttag ccccttgacg atggccaatc gtctgactga aaaagaacgt aaagaacaaa
    30541 aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa tcagccgaaa aaagaacctg
    30601 acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca aggggtagaa aacttactaa
    30661 ttcgtatcag tcgctgctgt aatccgattc ctggtgatga tatcgttggt tatatcacta
    30721 aaggcagagg gatatccatt catcgtcgag attgtccgaa tgttcagcct gacaaaccaa
    30781 atgtagcaga acgtttgatt gaagtcgaat gggaagatac atcgaataca cgaaaagagt
    30841 atgatgcaga tttggaaatt tacggctata atcgttcagg cttattgaat gatgtacttc
    30901 aaacagtcaa tgcgctaacg aaaaatctca acagcgttga agcacggacg aataaagata
    30961 aaatggcgac gatccatttg acggttggta tccagaattt atcccaccta aagagtatcg
    31021 tggataaaat caaagcagta cctgatgtct acagtgtacg ccggacgaat ggataggagg
    31081 acagatatga gagcagttgt tcaacgggta agtaaagctg ctgtgtcagt cgatcagcaa
    31141 gaaattggaa aaattggcta cggcctactt gttttattag gcattcatga aaccgatacg
    31201 caaaaagatg tggactatct ggtaaaaaaa attgcacaaa tgcgtatttt tgaagatgaa
    31261 caaggaaaaa tgaatattag tgtagaagat gtgggaggac aaattttaag tatctctcaa
    31321 ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa gctttgtgga agccgcacga
    31381 ccagaaacag ctattccttt atacgaatca ttcaatgaag gaatcagaag tcgcggcatc
    31441 acagtcgcta ccggacaatt cggagcagat atgtcggttt ctctcgtcaa tgatggacct
    31501 gtaacgatca ttattgattc taaaaacaaa taaagtaatc tggttttcac tagtaaaaac
    31561 tatgaaacac gtcgcttaag ttagactgat aaactctaac ttaagtggct tttttgtctg
    31621 caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta agcttaaatt atacaagtta
    31681 ttttttatag gaggttgctg aagatgaaag aagtaccagt agtagatatc aaaatcacag
    31741 atttaaaaaa attgtatcaa aaaggataca acatgttgga ggagttacgc catgaagcgg
    31801 acgctcccgt cgtcaaagca aagattttca ataaagaagc tatcacgatc tacggatcat
    31861 cagcagcaaa agtattttat gatccaagga atttcaaacg aaaaggtgct atgccaaaat
    31921 tagtattgaa gacacttttt ggtcaaggtg gagtacagac tttggatgga gctgctcatc
    31981 accatcggaa aaatattttt atggatctaa tgacaccgga aagaatggaa gattatcatc
    32041 gtatcttaga taagaatctg acacaagcac ttgaagcaca gcatggtcaa tttgaactat
    32101 ttgatttaag taagatggtt ttctttacat ctatttgcga gtgggcaggt atcaatttat
    32161 cagcgatttc taaagatgag gtcgaaaaat tagcagaata tcaaatctct atgatcagcg
    32221 gaacgtttac ttctccgatt gatcacataa aaggtgtcga gaatcgcaaa aaatcagaaa
    32281 aatgggcgca aggcttgatt gaagaagctc gacaaaatcc tgtggctgga aaagaaaatg
    32341 tggcattata tgcttttgcc aatgccacag atttagatgg tcagctttta cctctggaag
    32401 tggcagctgt tgaattattg aacatcatcc gtccaacggt tgctctaact gtgtgggcgg
    32461 cattgatggg acatgcactt ttcagtagac cagatttgta tcagcaatta aaaaatgact
    32521 tttcgacgtt acaagatccg tttattcaag aaatgagacg ctattatcct ttcttcccaa
    32581 tgctacctgc gatttcgctg aaagaagtag aagtagatgg ttatcgtata ccagaaggca
    32641 gttgggttat tttagattta tatggaacag accatgatga acgaacagtt gaagcgccag
    32701 attcctttat gatcaaacgg tatgtaggga aagcaaaaga tatttcctat aaagaagaat
    32761 atgagatgat tgcacaaggc gggggaaatt ttcgacaaat gcatcgctgt gcaggagaat
    32821 ggatcactct tcatagtcta cgtgtgtttt ccgatcagct agtaaataag tttgagttct
    32881 ctgtacctga acaagattgg acgattccat tcaatcagtt tccgacttat ccgaatagcc
    32941 gagcgctact ttacaagaat tagattagca taaacttatc gaaaaaaagg aagatcaaac
    33001 agtgctgatc ttcctttttt catattacta taaattgata aggtcaattg atcaaaatcc
    33061 acgaaatgct tcatcaatgg tttgataatc ttcattggat aaatgcaaat ctaaagcttg
    33121 gacattgtca gatacttgct ctggacgctt agctccaggt ataactacag acactcgtgg
    33181 attcttcatg taccaagcta aaacaagttg cgcaggagtg gcttggtatc ttttagcaat
    33241 ggggcgaagt acatcgacag cggttaaaat ttctctgaaa cgttctcctt ggaaatctgg
    33301 atttcttttt cgaggatctc cttcaccaaa ttgtttttcc tcaccaagtt catattttcc
    33361 tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa ctgattttgt ttttttcaag
    33421 ataagggaat aattcttttt cagcctgccg atggatcaaa ctgtatttat cttctactac
    33481 atcgacatat ccatctgcat tcgcttcttt caattgttct aacgtgaagt ttgacacacc
    33541 gactgctcgg atttttcctg cttcttttaa ttcgtgcaat gtagcaactg attcattttt
    33601 tggtgtgctt tcatccggaa agtggatata aaaaatgtcg atgtaatcag tttgcagacg
    33661 ttttagtgca tcttccaccg attgtttgag aaactcagga gaattatcaa atgttcgccc
    33721 tttatttggt acatgagcag cttttgtagc gatgacgaca cgtgagcgat catattcttt
    33781 ttccttcagt acctcgccaa tcagttcttc ggaacggccg tttccgtaag cataagcggt
    33841 atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact acttgttttc ctgtctcatc
    33901 ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt gctcctaatc caagctgttc
    33961 tgcgtagact tgtgaatgtc cgattcttat ttctgccata gctgattcct cctttttgtc
    34021 tagtctaaaa caaaatacca aaaagctgaa ctaaaacgtt tttgtgaggg gaaatagtca
    34081 gatatctctt gactttgaga ctggttttta gtaggttata agtaatatcg aatgtcaatg
    34141 aaagagcgag taagtttttg aaactttaca agagaggatc atcgaggctg aaaatgatct
    34201 aaagtttcat tagcctaaag acactctgga gatggacgag tgaaaagccg tcccgcgtac
    34261 gagcgttatt cgtaagagga aagagaaatc tttcaaaatt aggtggtacc gtgtatgaat
    34321 ttcattcacc cttgttcatg atgaacaagg gtgatttttt tatttacata gctaagaaag
    34381 ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa atgatatttt gccaggcgaa
    34441 tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat tattcagaga ttatcagtat
    34501 aatgaaatgc gtacaccgat ttttgaacac tatgaagtga tatcccgaag tgtaggggat
    34561 acaacggata tcgtttcaaa agagatgtat gatttttatg acaaagggga acgccatgtg
    34621 acgcttcgac cagaaggtac agcaccaatc gttcgttctt ttgttgagca taaattgttc
    34681 ggcccagagt atgcgaaacc gttcaaaact ttttatatgg gaccaatgtt tcgctacgaa
    34741 cgccctcaaa aaggacggtt acgtcaattc catcaaatcg gagtagaagc atttggatca
    34801 gaaaaccctg caactgatgt ggagagcatg gtgatggcac ttgatttctt caaacagttg
    34861 gggatcacgc aaatccggct agtcatcaat tcattaggtg ataaagaaac gcgtcaagcc
    34921 tatcgtcaag cattgatcga ctatctttta ccttttgaat cagagctgag tgaagactct
    34981 aaacgccgcc ttcatgaaaa tccattacgc gtattggaca gtaaagacaa acgagatcaa
    35041 aaatttgtgg cagaagctcc atctatctta gattatctaa gcgagcctgc tcaaaaacat
    35101 tttgataccg ttgtttccat gctggatgca ttggctgttc cttatgaaat cgacagtaat
    35161 atggttcgcg gactagatta ttacacacat acgatttttg aaatcatgag tgacgcacca
    35221 aaaatggggg cacaagcaac gatttgcgca ggcggacgtt atgacaatct agtggaagaa
    35281 ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg gtatcgagcg attactcttg
    35341 actatggagg cagaggaagt agttatccct gcatttaatg agttggatgc ttacgtggtc
    35401 gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg tccaagcgat tcgaaacttt
    35461 ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa aagcgcaatt taagacagca
    35521 gataaagcga atgccaaatt agtattggtg atcggtgaag atgagcttgc tagtcaaacg
    35581 attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt ttccattaga agagatatat
    35641 gaacattttg atgaagtcta tgatgaaatg actttattcg agtaggagga aaaaaataaa
    35701 tggcacaaag aacgatctat tgcggattag tttccgaaca acaattagaa caaacagtta
    35761 cattaaaagg atgggtacaa aaaagacgag accttggggg agtaatcttt atcgacctac
    35821 gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga aatcaacaaa gaagcatggg
    35881 aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt gactggggaa gttagaagac
    35941 gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga attcgaagtg attgcaagtg
    36001 aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca aattgaagat gatcaagcaa
    36061 tcagtgacga aatacgtttg aaatatcgtt atttggatct gcgtcgtcca aaaatgacta
    36121 aaaacatcaa attaagaaat gcgacaacaa aagcgattcg tcattattta gatgataatg
    36181 actttctcga tatcgaaaca ccttacctag ggaaatctac accagaaggc gcaagagact
    36241 acctagttcc ttcacgtgtc catgctggac atttctatgc gttgccgcaa tctcctcaat
    36301 tgtttaaaca attgctgatg aatgctggat tcgaccgtta ttatcaaatc gttcgttgtt
    36361 tccgcgatga agatttacgt ggagaccgtc agcctgaatt tacgcaagta gatattgaaa
    36421 caacgttctt aacagcagaa gaaatccaaa cttacacaga gggattgatt gcgaaggtaa
    36481 tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc tcgtatgacc tatgatgaag
    36541 caatggctcg ctacggcagc gacaaaccgg atacacgttt tgatatggaa ttgatcgatc
    36601 taagcgatac agtcaaagaa gtagaattca aagtcttcca aatggctctt gaaaacggcg
    36661 gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg ctactcacga aaagacatgg
    36721 atcagttagg tcaatatgta ggacaattcg gagctaaggg gcttgcatgg ctgaaagtag
    36781 aagaagacgg attgaaaggt ccaattgcta aattcatggg agaagcaaca gaagcaatca
    36841 ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt tggcgcagat aaaagtgaaa
    36901 tcgtcgctgc tgcattaggt gctatccgga cacgtttagg aaaagaatta ggactaattg
    36961 atgaatcgaa attcaatttc ttatgggtaa ctgattggcc acaatttgaa ttttcagaag
    37021 aagaaggtcg atatgtctct gctcaccatc cattcacgat gccaaaagaa gaagatatcc
    37081 cgttattggc tgaagaccct gcaaaagtct atgcagaagc ttatgatatc gtcttgaacg
    37141 gttatgaatt aggcggaggt tctatccgta ttcatactcg tgagcttcaa gaaaaagtac
    37201 tagaaactct aggctttaca aaagaacaaa tggaagaaca atttggtttc ttgttaacag
    37261 ctttagatta cggattccct ccacatggcg gtattgcatt aggattggac cgttttgcaa
    37321 tgttattagc cggagaagat aatattcgtg aagtcattgc ctttcctaaa aacggaaaag
    37381 cagcagatgt gatgagtgat gcaccaagta tggtttcgcc tttacaattg ttcgaattga
    37441 atattgatgt aacgaatata gaagaatagc cgataaaaag gtaaaaagga tttgtcgaat
    37501 acgcttcttt tgacaacctt gatttaattg aaaaacactt tataatgaag ccataacata
    37561 taaagcgggg cttttccatg aaaaaaacat tcgaaaattg ggcttatcat gattacacga
    37621 ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc agtcgcattg aatttctttt
    37681 atcagccagg acatatttat tcaagtggta ttactggtct agctcagatt ttgacgactt
    37741 tgtcaaaatc actgatagga ttcgaagtac cggtatcaac aactttgtat ttactgaata
    37801 tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa gtttacaatt ttcactttta
    37861 tcacagtcac tttgacctcc ctttgtatcc atattttacc ggaaacagtc ctatctaccg
    37921 atccaatcat ctgtgcgttg tttggggggg ctgtgatggg actaggtatt gggctagcgt
    37981 tgagaaacgg cctatcatcg ggcggtctag atatcgtgag tatcacgatt cgtaaaaaaa
    38041 caggaaagtc gattggttct atttcgatct acttcaatgc attgatcgtt tttgttgccg
    38101 gaattctatt tggctggcaa tatatgtttt acagtacgtt gtctattttc gtcagtggaa
    38161 aagtaactga tgtcgtttat actaaacaaa agaagatgca ggtaatgatc gtaacgaaac
    38221 atccagaaaa agtagtaaat gaaatccaaa actgtatgcg tagagggatc acgatcatca
    38281 atgaagcaga aggtgcttat aagcatgata agcagacagt attgatgacg atcgttacac
    38341 gatacgaact gcctctactt agagaagcaa tgaaagcttc tgatccacaa gcttttgtaa
    38401 gtattgcaga aaacgtccag atacttggtc gtttctatga ggatggcatt tagatcgagt
    38461 ttgacaaaaa ttcatgaaat actgctgtag acagacgttc gtttgtctgc agtttttttc
    38521 taccatagta gaatcagcaa agaaaaactg cttttttatt tgaaattttc ttaaagttga
    38581 aaaaaagcat gtttattttt ttaaatttat gggatgatag aaaaaaatag tagagaaagg
    38641 acacgattct acttgctatt ttcacttaat acccgtatat tacgaatgaa aaaagtttat
    38701 gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa aaaacagccg ctacatcact
    38761 gggtttgatg ggctccgttc attagctgtg gtgggtgtta tcttctatca ccttctgcca
    38821 actagtatga aaggcggcta tttgggcgtt ccgatttttt tcgtcgtatc tggttatttg
    38881 atcacggatc tgctgcggca ggaatgggaa caaaatggaa aaatcaatat ttggcaattt
    38941 tatgtcagaa gaatgaagag actctatccg gcacttgttt ttatgcttgt gacagcttcg
    39001 gcttatatca ctttgtttca gcgagggctg ttaaacaatc ttcgaggagt tgtggtcagc
    39061 agcttactgt atgtcaacaa ctggtggcaa atcagtaacg gtttatctta tttcgatcga
    39121 tttgctaatg agtcaccgtt tacgcatatc tggtctttag cagtagaagg tcaaaactat
    39181 ttggtttggc cgatcttgtt tgtattgttg atggtatttg ttcgtaaaag aaaatggatc
    39241 ttttatactg tgttaggtac atccttcctc tccgccatct tgatgatgat cttgtataca
    39301 ccaggaggcg atccaacccg tgtttattac ggtaccgaca ctcgtctgtt ttctatatgg
    39361 ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt taaagaaaaa catcccgaaa
    39421 caagcgaaaa atattctgaa tatcgctgga ggaatctcgc ttttggcact gattctttgc
    39481 ttcttctttt tagatgatca ttacaatttc atctattacg gaggaatgct cctagtgagt
    39541 ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg gagcaagttt gaatcgatgg
    39601 ctgacaaatc cagtatttac ttggattggc aaacgaagct atggcattta tctgtatcag
    39661 tttccagtta tgatttttta tgaagcaaag gtgactgata ttgccgatca tgttttgttg
    39721 catactttag tggaaatcac attgattcta atcatcagtg aactttctta tcgatatgtg
    39781 gagcgtccgc tagcacgttt tgattatggt cgtacattcc aagtgatgaa aggatggttc
    39841 agcaaaccga tcatcagtaa gagcaaacca tgggttgttc caggcacatt acttgtagca
    39901 attgcactcg ttggtttcgt tacggcaccg aaaaacgctg taacagccga tcaaaaacaa
    39961 ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag aaaccagaaa caattcagaa
    40021 aacaccacta gttcggttga ccaagcgatc cttgataagt acgagttgtc caaggcacaa
    40081 gggaataagg cacaaaaatt agaactaacg gcatttggtg attcagttat gttggatgct
    40141 gcaacggatc tacaagaact ttatccaaaa gtagtggtag atggagatgt cggacgacaa
    40201 ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac aagatttgtt gaaagacact
    40261 gttctgattg gactaggaac gaatggctca ttctcggaag ctcagtttga tagtgtgatg
    40321 gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc gagtaccgac gaagcgctgg
    40381 caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa aatacgacaa tatgacgctg
    40441 attgattggt acagctacag taatgaccat agtgactggt tttatgatga tcaagtccat
    40501 ccaaatcctg aagggatgac acattacatt cacttagtca gcgaagcctt gctaggagga
    40561 agttcaagta cgaacagcag tgagacaaac gtgacagaat gatagctaca aaaaacttca
    40621 ggcaaaaaca tttgtttttg cctgaagttt ttttatattt accgtgtttt taacattcat
    40681 atagattcag gaagcaaaac ggttgagtgt gtctgtaaat aacgttcttt ttgttttcgg
    40741 gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc ttcttgaaga aaatacttct
    40801 gcatggatca tcttaacagg tcttcttttt tgaagacgag tatatttagc accagtacca
    40861 ttgttatgtt cctctaatcg tctagaaaga tcggttgtat atccaccata aaatgtctga
    40921 tctttacaga ataatacgta aaaataatgt tcatttgcca tagagcatct cacgaatctc
    40981 tgcagtgtat tctccatcca tattgtaagt gatcaatggt ggagcgactt tgaatccgtc
    41041 taatttgcct tctttgattc cttcaactaa caaaatattt gcctcttttc caggttttgg
    41101 gtaaacaaat tggatccttt taggtgcaat tcgatagtct tccatgacct gaatgatttc
    41161 taagaaccga tcaggacgat ggaccatagt aaagcgtcca tttgttttta gtagcttact
    41221 tgaaatatcg atcacttctt ctaacgtcgt atgaatctca tgacgggcga ttgccaggtg
    41281 tttattaggg ttcgttttat ttgttggcag ccctttgaaa taaggtggat tacagacgac
    41341 taagtcacaa gaattatgtc gaacgacaga taagctgtct ttcagatcga tggtgtggac
    41401 agtcatttgt tcatttaaat ggttaagcgc gatactacgt cttgccatgt ctgctagacg
    41461 aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt ttacttaaaa aaagtccaac
    41521 tgcgccattt cctgcacaaa ggtcaacaat cttccctttt ttaggtacac gggaaaagtg
    41581 agcaagcagc acagcatcta aagaaaaaga aaacactttg gaactttgga taatcttgat
    41641 atcttctgcg tataattggt cgattcgttc gtcttcgtga agcatggatt ccctccaaaa
    41701 tgaaaaaaat agtcgtctgt attatactat ttttattaaa aagaaccaag gtggcttgtc
    41761 aaacctctat tttttatgca tactatgacc ataagaaggg aaaggaagag actatgtttt
    41821 atcgatttat gcgcggggta gttcgagtac tattagcctt agttaatgga aatgcccgct
    41881 atgagaataa agaagtttta ccgcaagatg agaattacat actagttgct ccccatcgta
    41941 cttggtggga cccattatat ctggcggtag ctgcagcacc caaggaattc agctttatgg
    42001 caaaagaaga actgttcaaa aatccagttc tgcgatttat attaactcga tccaatgctt
    42061 ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa aacacctgta aagattttga
    42121 aatcgacaaa tttgagtttg atcatgtttc ccagtgggac aagacatgct acagaactta
    42181 aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa aatcgtgcca gctgtatatc
    42241 aaggtccgtt gacacttggg gatctgttca agcgtcagag agtgacagtg cgtttcggcg
    42301 aaccaatcga cttatcagat atcaagaaaa cggataaaga aggtatggcg gagatcgaac
    42361 gacgaacaca agcagctttt gacaaattgg acaaagaagt gaaccctgat ttcaaatatg
    42421 aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg gtcttttgaa tctactgtcc
    42481 tgttcagttc agactttttc aatgaaaacg agggagagac gtcaagtctg ccctcttttt
    42541 gcgttccaat atgtaaaata gaagacaggt gtcatgtaat ggatcaaagt gttataataa
    42601 ttagaaggac attttttgag gtgattgaat gcgtttttta catacagccg attggcatat
    42661 cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag cgtcatgtac tatcttctat
    42721 actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg attgccggag acttatatga
    42781 taggagtgtc ccagctgttg atgccgtaga attatacaat gaattgatgg tcgattggaa
    42841 tttaaaggaa aagatcccga tttttgctat atcaggaaat cacgatagca gtacgagact
    42901 ttcagcgggt acgccatggt tcagttattc gaactatttt ttgcgaacac agctagcaga
    42961 agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc tttcttcctt actttgaacc
    43021 aattgcagcg agattatatt ttgaagatga caatatccga acgatcaagc aagcggtagc
    43081 caaggtgata gataaaatgc aggagctatt tgattcagaa aaaaaacaag tattgattag
    43141 ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa acgaaaatcg aagtaggcgg
    43201 gttggattcg atccctggtg aactacttac accgtttgat tatgtagcac taggacattt
    43261 gcataatcaa gctgctttga gacaggataa tgctcgctat agcggttccc cattgaaatt
    43321 ctctttatct gagatcaacc aaaaaaaagg cgtatggatc gttgacctga caacaggcct
    43381 ggagttgaat tttagggaga tcgaacccct gcatgatatt gaagaaataa cagcgagttt
    43441 caaagaattg ctggatcctg ccttttatca gtccgtcaat cgggagaatt acatctatat
    43501 ctatctcact gatagaacga tcatcccgaa tatgatgaac cagcttcggc aaatatatcc
    43561 tcgtattttg gggattgaac gggcaaacgg tcgagcagaa caaacaaagc gcaaacgaaa
    43621 agtactagaa atgaaagatc ctcaaaaatt agcagaagca ttttttagtg aaatgacgga
    43681 agagcagcta actgcaaacc aagaaaaatg gctcggagaa acgttgcaag aaatcatgga
    43741 aatggaatga tcaagaatga aaccgaaaaa attacaactt aaaaattttg gtccttttat
    43801 caatgagacc gtagattttt cacgtttgac agaagcaccg ctttttttga tcagcgggaa
    43861 gacaggagct ggcaaaacga cgatttttga tgggatcacc ttcgcacttt ttggtgaaac
    43921 ttccggaaga cttcgctctg gaaaagagat gcgttctttg tttgctacac cagacgaaga
    43981 aacaagcgtg actttttctt ttgaacatca gcagatgagc tatgaaatcg aacgaaaacc
    44041 agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa aaacaggcag ccaaagtaac
    44101 gttgaccatt tttgatggga aaggaaaaga aataaaacaa atcacaaaac gtacagaagc
    44161 agatcagttg atcagagaac tgatgaatct cgatgcgaaa cagttttctc aaatcgtttt
    44221 actaccccaa ggagaattcc gtaatttttt ggtttcatca agcagtgata aagagactgt
    44281 tttacgtcat ttattcggta ctcaattttt ccaacagttc aatgagcgat taaaagaaaa
    44341 agcaaaacaa cagcaacaaa aattggatca tttagagcaa gagctgcatc ttctgcaaaa
    44401 aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg tttgaagccg ttttagccca
    44461 atggacaaac catcaggcaa tactcgaaaa acaaatcacg gaagaaaaag aagctctaac
    44521 ggaacttcag gaaaaacaaa agcaactaga aaattcctac tatcgttttg aaagcttgaa
    44581 aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa aaggaattag ctgctcaaaa
    44641 agacgaaata gaggaaaaga aacgatggat tgggtattat gaatttacgc aacgattagt
    44701 cgaaccaatc cagcgcctac aagaaataaa agctgaaaaa atagaactgt cgcaaaaaag
    44761 tagtgagcaa acaaagaaac tagcgatgac tacgcagaat tatgaagagt ggcaaaaaaa
    44821 tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa gctgctcaaa aactgcaaaa
    44881 caaacagatg atggtgccaa ttgtcgaatc cttacgtagt aaaaaacaag acgcagaaca
    44941 attaacaatt tcattggata aagaagaatt gaatgccgag aagctgtatc aaaatctcgc
    45001 tatctatcag gaaagaactc gaattcttca agaaaattta ctggatcagg aaaaactgca
    45061 agaagatcgt cttgcttttg gacagttaaa atatctagat gaaaagcagc aagaaataga
    45121 aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata agagaagaac tcaaaaaagc
    45181 aactgaagaa ataacaaaaa atagtcagct attgaaagaa cagacagaac aagcagaaca
    45241 gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt cagctttttt tgcgtccagg
    45301 ggagccatgt cttgtttgtg gatcaacgga acaccccata caacaattaa aacacgaaca
    45361 gccaaataag gaagatatct taaaagtaga acaacaactg gcagaagctg agtctgctgt
    45421 agaaagaact cagcaaatca ttgccaaaag tgaagcacat gaaaataatc ttcaacaaca
    45481 attatcagat ttagaacaaa aaatcatggc aacgaatata caattggctg aacaagaaga
    45541 acacttgcaa caggctttga aaaaggcatt tcctgagata acagaacaaa aaacaaaaac
    45601 agctcttgta gtaatcgaac aatctttaga tagacgaaaa agcaagatgg ccaatgcaag
    45661 aatagagctg gaagaaataa gacaacaagc agaaaagctc gaacaacaat tagctgtcta
    45721 caaacagcag cagacagaaa aaaataatca gctccagcaa ctgcaaggag aaatcaaaag
    45781 tttagaacaa caattgcaag atacggatag taactgttta gaagaggaga tacgacgact
    45841 tgaaaaacag ttagaagaag actcgaatca actagctgtt gagcagaaag caggagtgca
    45901 attgttgcaa gatcttcata cgcttcggac acagcttgat cttcaacatg aacaaataga
    45961 aaaaatagat gaaaaaatag aaaaggaaca agaaagaata gctaaaaagt tagaaagcca
    46021 gtcgtatttt tcaacaattg aagaaatctg tgcatttgca caacagcaag cacaatataa
    46081 agaaaaccaa cgtacagtta cttcttatca tgaagagcaa ttagtgacag ctgaccggct
    46141 gcgtcaatta gaaaatatcc agctaactga gacattccca gatacagaag agatcagcca
    46201 acagttagaa gaaataagac gtatgatcga aataaagcaa gaaaagatat acggtttaca
    46261 agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt ctttcgattt atcacacaag
    46321 ccagacgaaa ttagatgagc ttacgcaatt acagcagctt tcgcaaacat tcaacggaga
    46381 aaatcctaag aagactagtt tggaacggta tgtgcttcag gtttatcttc aagaagtgtt
    46441 acaagtagca aatgatcatc tccaacgttt aacgaaaaat cgttatcaat ttgagctagc
    46501 ggataccatt ggcagttatc gagggaaaac cggattagaa atcaatatct atgatgatca
    46561 ggcaggtatg tctcgaagtg cgcataccct gtctggcggt gagagtttta ttgcagcact
    46621 ttctttagca ttagctcttg ccgatgtgat ccagacacaa gctggtggtg tagcaatcga
    46681 tgcattgttt attgatgaag gatttgggtc attagatgaa gaagctttgg aaatggcaat
    46741 ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc ggcatcatta gtcatgtaag
    46801 agaattgaaa gaacgagtat tacaacaaat aagaattgat acagaaggta gcggacaaag
    46861 caaaatacgc tatcaacttg gataaaaagg gagattggta actatgaaat ggagtattcc
    46921 agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa ggccgagtgt tatcggttgt
    46981 ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg ggcagtgaat tgtatatggt
    47041 tgatttggat ggtacagcaa aagagataga ttactgccaa tgtccttatt gggaggaaca
    47101 taaatattgt aagcatacag ttgctgtgga actttattta cggtcgaaaa atctatctcg
    47161 tatcatgaaa aaagaccagc caatgctaga accggtaaaa gcaacaagtg agggagaaat
    47221 cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat cctcaagcgg tgcaaccttt
    47281 gattattgaa taccaagtag aaacgattga gactaatcag tatcacccag agctttctat
    47341 tttggcactt tacttgcgta tcggttcatt ggcatcaccg aaaaaaacat atatcgtaaa
    47401 aaacatctat gattttttac aagcttacgc agaaaaagaa acttacactg ttaataaaca
    47461 gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa gatcaaaaaa tactcacgca
    47521 tcttgcagga agtgctcaga cgcatcaatt attaggtacg aacggcttac aagtcaaagg
    47581 aaaactagat aaaagatatc tgcttctccc agtagaacaa gcccgcttcc tgttagagca
    47641 gatgaatcag actacacgtt tgcatctgca gataaatgaa caaaacgatc aaggaataca
    47701 attttccgat caaaacaaac ctttatcatt caaagtggaa aaatttggag aagattattt
    47761 gctgcaagca ttgaatgatt ttgatttttt ctttatgcat tatcagtggg gagttatcca
    47821 agggacattt tattctctga cgaaatatca acaaacggtt tatcaaactt ggaaacaatt
    47881 gattcgccga ttggagaaac cagaagtagt gttcaagaaa aaagaattac cgtctttgtt
    47941 taaagagatt atccctctgc tttcagagat cggcgacgta gctattgccc ctgcagtaga
    48001 agaggaagta gcagatatcc ccgtcgaatt tattttcttt ttccgaaaat caaaaggaaa
    48061 aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc tattcgactg acccgaagca
    48121 tgaggtctcg acagaacagg cttttcaggt gttacgtgac acagtagaag agaaacgagt
    48181 acttgatcta ttcagaatgt atcgctacca gaaaaatgaa actggttatg aacgtccatt
    48241 gccaagcggg gaagaactat atgccttttt ccgcacagaa ctatctgtct tccgtcagtt
    48301 tggtgaagtc agacttggaa gaaaattgcg agagttgtat ttagatgcgc ataaacatca
    48361 accgaaaatc gaagtaaccg agaccggttc atggctcgat attcgattcg atgtgacagg
    48421 gatagaggag caagaaatcg atcatgtcct gcaaagcttg ctgagaaatg atgcttttta
    48481 tacattagaa aatggtcagg ttctttcttt tgattcagaa gaatttcaac aaacaagcca
    48541 agtgttgcaa caattacggg aatcgatacg tacagaagaa ggaacgatcc atgtacctaa
    48601 aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc aatgctactt ttagtgaatc
    48661 gttccaaacg atggtacaag atctcattca tccagaaaga taccaggcac agcttcccaa
    48721 aggattgaat gcaacgatga gagattatca aaagcaaggt tttcgatggt tgaagatgtt
    48781 aggtcattat cagtttggcg gtattttagc cgatgaaatg ggacttggga aaacactaca
    48841 gacaattgcc tttttacttt cggaaaaaga agaacggaaa agcttctctg ctttgatcgt
    48901 agcgcctgcg agcttaattt acaactggca ggcagaggtg agaaaattcg ccccttcttt
    48961 aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa gaattactgg ctaaagacac
    49021 agatatccga gtgacttctt atgccagctt aagacaggat ctagctaatt atcagtcgca
    49081 aaaaattgat tatttgattc ttgatgaggc acaaatggtc aaaaatagca gtacgaaaac
    49141 tgcacaagca ttgagagaat tagctgtacc tcagcggttt gcactgagtg ggacaccaat
    49201 cgagaataat ttagaagaat tgtggtcatt gtttgcaacg attatgccag gatttttccc
    49261 gactaaaaca aaattcaggg aacttgccgc agaagaaatt gcgcaaatga ttcgaccgtt
    49321 tattttacgg cgagataaac aaactgtgtt gaaagacttg ccggaaaaaa cagagatgaa
    49381 tctatattct gcacttacag aagaacaaaa aactgtttat ttagcttact tgcgtcaaat
    49441 gcgtgaagaa atcacatcaa tggattctga agcattcaag aaaaaccgga tcgggatact
    49501 tgctggtctg acaagactgc gacaaatttg ctgcgatcct cgtctgttta ttgaagatta
    49561 ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta ctggtagctg ccaaagagaa
    49621 caaacgaaga gttttgctgt tttctcaatt tacagggatg ctgactatct tgcaagaaga
    49681 gttagccgag ctagggatct cgacatttta tttaagaggc agtacgaaac cacaagatcg
    49741 gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat gtttttctga tttccttaaa
    49801 ggctggggga actggattga atctcacggg agcagatacg gtcatcttgt atgacctttg
    49861 gtggaatcct gccattgaag aacaagctgc tggacgtgca catcggatcg gacaaaaaaa
    49921 tgtggtagaa gtgtggcgta tgatctctga aggaacgatt gaggaacgca tggattcact
    49981 ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa ggtaatgaag aacagttgac
    50041 gaaactgact gaagaagaca tccgcatgat tttaagtgta ggagaaatcg aggagtaaga
    50101 gactcgaaaa agcgttcagt aatgggtaag aaagcctttc taaagaagcg attgtttatt
    50161 tgatttaaaa aatagcaagg aggctgggat tccattttat cccagcttcc ttgctatcat
    50221 ttttttattt ctatttttaa aggttataca aagattgtct tcattgtctc taacagctga
    50281 tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt caattttgcg ttctcgatgg
    50341 ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta gaacatcatt gtcgtaatta
    50401 tcgccaacgt ataaggtctc ttctggaagc atatgaaatt ctttctcagc cagctgaaaa
    50461 atctcttttt ctggtttttg gaaacctgtt gcttgagaaa tgagcatatt gcgggaagga
    50521 atccaattgt tcaattgaag ttgcttcagt ttttttgtct gatggtcagt cggcccattt
    50581 gtgataattc ctaatgggac attcttttcc ttcaagaaat cgagggtttt tttgacctcc
    50641 tcatgcaagc agatattatc aagttcttcc tcgtaaattt tttgaaataa gaggccatct
    50701 tcttccgtaa tatgagggta gtctaaatct tttagtgatt ggctgatccg atgtgctcgc
    50761 atatattcta gtgtccaatc tcctgccatt acttttggga agttttcatc actatgatgg
    50821 cggaaccgga tatatagtgg atgcatatct gcatctgaaa caagcggaac gactcttttg
    50881 accgcgtttc gaaatggctg ctgctgatca tacatcgtat catcaacatc aaacacaact
    50941 gatttaatca aaattttaca cgcctttcgg ttttcattga ttttttcaca aatccttgac
    51001 tattgtaaca gaaaaaattg tctaaaaaag ctgataaata aaggtttttc ttactatatt
    51061 tctatttcct tgacagaata aggtttttat atttcagttt ttttcactaa aaatcgtgaa
    51121 acacgtcaat aagtttgatg aacaaattaa tcattatggt agaagtcgat tgatttattt
    51181 taatgcaatc tctgtggaat tttcgaaaga tttatttttt taatacagtc tcaatataac
    51241 tattcaaaca taaaataacg ttatttgatt tatttgttta tagtaaattt tatttagtaa
    51301 tcattgcttt aaaatactac gcttatataa cagagaaaat aagcgttata ataaagaaca
    51361 gtattattta aaa
//
LOCUS       DACGLI010000014        51284 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.015, whole genome shotgun sequence.
ACCESSION   DACGLI010000014 DACGLI010000000
VERSION     DACGLI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.015"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(114..1316)
                     /locus_tag="IXT22_000893"
     CDS             complement(114..1316)
                     /locus_tag="IXT22_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4862276.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            1433..1948
                     /locus_tag="IXT22_000894"
     CDS             1433..1948
                     /locus_tag="IXT22_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4862277.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2147..2593)
                     /locus_tag="IXT22_000895"
     CDS             complement(2147..2593)
                     /locus_tag="IXT22_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4862278.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2640..4118)
                     /gene="msr"
                     /locus_tag="IXT22_000896"
     CDS             complement(2640..4118)
                     /gene="msr"
                     /locus_tag="IXT22_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4862279.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(4472..5101)
                     /locus_tag="IXT22_000897"
     CDS             complement(4472..5101)
                     /locus_tag="IXT22_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4862280.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(5085..5549)
                     /locus_tag="IXT22_000898"
     CDS             complement(5085..5549)
                     /locus_tag="IXT22_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4862281.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(6036..7304)
                     /locus_tag="IXT22_000899"
     CDS             complement(6036..7304)
                     /locus_tag="IXT22_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4862282.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(7535..8272)
                     /locus_tag="IXT22_000900"
     CDS             complement(7535..8272)
                     /locus_tag="IXT22_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4862283.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8339..8908)
                     /locus_tag="IXT22_000901"
     CDS             complement(8339..8908)
                     /locus_tag="IXT22_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4862284.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            9036..9908
                     /locus_tag="IXT22_000902"
     CDS             9036..9908
                     /locus_tag="IXT22_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4862285.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            10250..11122
                     /locus_tag="IXT22_000903"
     CDS             10250..11122
                     /locus_tag="IXT22_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4862286.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            11119..13077
                     /locus_tag="IXT22_000904"
     CDS             11119..13077
                     /locus_tag="IXT22_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4862287.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(13409..14260)
                     /locus_tag="IXT22_000905"
     CDS             complement(13409..14260)
                     /locus_tag="IXT22_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4862288.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            14383..14850
                     /locus_tag="IXT22_000906"
     CDS             14383..14850
                     /locus_tag="IXT22_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAQ4862289.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(15113..15595)
                     /locus_tag="IXT22_000907"
     CDS             complement(15113..15595)
                     /locus_tag="IXT22_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4862290.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(15695..16558)
                     /locus_tag="IXT22_000908"
     CDS             complement(15695..16558)
                     /locus_tag="IXT22_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4862291.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            17156..18031
                     /locus_tag="IXT22_000909"
     CDS             17156..18031
                     /locus_tag="IXT22_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862292.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(18176..18328)
                     /locus_tag="IXT22_000910"
                     /pseudo
     CDS             complement(18176..18328)
                     /locus_tag="IXT22_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(18596..19927)
                     /locus_tag="IXT22_000911"
     CDS             complement(18596..19927)
                     /locus_tag="IXT22_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4862293.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(20076..20789)
                     /locus_tag="IXT22_000912"
     CDS             complement(20076..20789)
                     /locus_tag="IXT22_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4862294.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            20964..22388
                     /locus_tag="IXT22_000913"
     CDS             20964..22388
                     /locus_tag="IXT22_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4862295.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            22687..23394
                     /locus_tag="IXT22_000914"
     CDS             22687..23394
                     /locus_tag="IXT22_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAQ4862296.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            23381..23704
                     /locus_tag="IXT22_000915"
     CDS             23381..23704
                     /locus_tag="IXT22_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4862297.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(23793..24830)
                     /locus_tag="IXT22_000916"
     CDS             complement(23793..24830)
                     /locus_tag="IXT22_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4862298.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(25151..26134)
                     /locus_tag="IXT22_000917"
     CDS             complement(25151..26134)
                     /locus_tag="IXT22_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAQ4862299.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(26549..27319)
                     /locus_tag="IXT22_000918"
     CDS             complement(26549..27319)
                     /locus_tag="IXT22_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862300.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(27312..28247)
                     /locus_tag="IXT22_000919"
     CDS             complement(27312..28247)
                     /locus_tag="IXT22_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862301.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(28563..30212)
                     /locus_tag="IXT22_000920"
     CDS             complement(28563..30212)
                     /locus_tag="IXT22_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4862302.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(30329..32932)
                     /locus_tag="IXT22_000921"
     CDS             complement(30329..32932)
                     /locus_tag="IXT22_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4862303.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(32944..33993)
                     /locus_tag="IXT22_000922"
     CDS             complement(32944..33993)
                     /locus_tag="IXT22_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAQ4862304.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(34019..34333)
                     /locus_tag="IXT22_000923"
     CDS             complement(34019..34333)
                     /locus_tag="IXT22_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HAQ4862305.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(34349..34795)
                     /locus_tag="IXT22_000924"
     CDS             complement(34349..34795)
                     /locus_tag="IXT22_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4862306.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(34796..36772)
                     /locus_tag="IXT22_000925"
     CDS             complement(34796..36772)
                     /locus_tag="IXT22_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HAQ4862307.1"
                     /translation="MKIEIIIVHLSCIQEVKIMGIEFSERQMKILYFLIENEHTTYKE
                     LSEQLYVSTKTISKDILILKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKIN
                     IADSPEDRLTYVFAKLLNTNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLV
                     SDRNGVRIKADEKSKRRLMSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDI
                     LKKVAELLNRYMNKTQLKFTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNT
                     LILIKMIEKAFSIIVPIDEQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVR
                     IKLNEFYPDEELINNLVLHLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEE
                     IEERFCIHFNEDEIAYVTLHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFA
                     DMVEIEDVLSINELQDRKVTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQL
                     NEQTEDAFLNLLDKRFCFFTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKL
                     SSTAMNDFAMPHIEVDFIKKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKI
                     YETFNEIASNHELLANLKTSSSFEKLVYILKEGL"
     gene            complement(36930..37826)
                     /locus_tag="IXT22_000926"
     CDS             complement(36930..37826)
                     /locus_tag="IXT22_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4862308.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(37819..38499)
                     /locus_tag="IXT22_000927"
     CDS             complement(37819..38499)
                     /locus_tag="IXT22_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862309.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(38500..39282)
                     /locus_tag="IXT22_000928"
     CDS             complement(38500..39282)
                     /locus_tag="IXT22_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4862310.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(39275..40192)
                     /locus_tag="IXT22_000929"
     CDS             complement(39275..40192)
                     /locus_tag="IXT22_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862311.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(40356..40679)
                     /locus_tag="IXT22_000930"
     CDS             complement(40356..40679)
                     /locus_tag="IXT22_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4862312.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            41467..44694
                     /gene="fss3"
                     /locus_tag="IXT22_000931"
     CDS             41467..44694
                     /gene="fss3"
                     /locus_tag="IXT22_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAQ4862313.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            44807..45121
                     /locus_tag="IXT22_000932"
     CDS             44807..45121
                     /locus_tag="IXT22_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4862314.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            45134..45508
                     /locus_tag="IXT22_000933"
     CDS             45134..45508
                     /locus_tag="IXT22_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4862315.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            45518..45853
                     /locus_tag="IXT22_000934"
     CDS             45518..45853
                     /locus_tag="IXT22_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAQ4862316.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            45936..47276
                     /locus_tag="IXT22_000935"
     CDS             45936..47276
                     /locus_tag="IXT22_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4862317.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            47354..48028
                     /locus_tag="IXT22_000936"
     CDS             47354..48028
                     /locus_tag="IXT22_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4862318.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            48261..48695
                     /gene="dcm"
                     /locus_tag="IXT22_000937"
     CDS             48261..48695
                     /gene="dcm"
                     /locus_tag="IXT22_000937"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4862319.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            48696..49403
                     /locus_tag="IXT22_000938"
     CDS             48696..49403
                     /locus_tag="IXT22_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAQ4862320.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLLPGKFEQGNRV
                     YEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFPNSTSRRGRLGKQSVHT
                     LLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVNSDSQLYKQAGNSVTVP
                     VIFDIARRLKELDVHGL"
     gene            49393..49683
                     /locus_tag="IXT22_000939"
     CDS             49393..49683
                     /locus_tag="IXT22_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862321.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            49942..51126
                     /locus_tag="IXT22_000940"
     CDS             49942..51126
                     /locus_tag="IXT22_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4862322.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            51141..51260
                     /locus_tag="IXT22_000941"
     CDS             51141..51260
                     /locus_tag="IXT22_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAQ4862323.1"
                     /translation="MGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKGK"
BASE COUNT        15765 a        10117 c         9269 g        16133 t
ORIGIN      
        1 aaagcttgca tctgcggtaa taagcccaac caaacgaaaa atatgagaag ctatttttgt
       61 ttggctgttc ttatgacttg atgcaggaca gctttttcac aacctctgat ttcttattct
      121 tcttcatttg tagcaaaata attacggtga taaatgatac aacatacact gataagaaca
      181 atggcacctg caaaataaaa cgcatagctt tcaccaatat gttcaccaat cacacctgca
      241 ataaatggtg ctaaagctcc accgaaaaag cggacaaaac tatagctgga cgaagcaacg
      301 tttcgttgca gacctggtat ttccatagca atcgtcgtca acagtgtatt gataattcct
      361 tggaaaaatc ctgctaacac aatgctgatc ggtacaagga ctggcataga agttccagct
      421 cctaataaca gcaaacaaat aatgaataag acaaatgctg ctaaaattgt ccgataagtc
      481 gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag caatagccag aagcacaccc
      541 cagccaaaaa atacaaaacc gacttctaat tcagaatagc caatcaataa aaatggcgca
      601 tacgcaagta aagtaaagaa tccgaaatta tataacaatg cgattagtcc aactgaacga
      661 agtttatgat tgcttaacgc tttgacacct tcccaaaggc ctacttttct ctttggtttc
      721 tcagtttcag gtaaaagtac cgctagggct ataaaaccgc aaaacatcaa aaatgctacc
      781 ccaaaaaatg gataacgcca tgaaccactg cccaagaccc caccgactag agggccaaca
      841 gccattccgc agccaagtgc tgcttcatac atcatgattg ctttttctgt gttaccaact
      901 aaaatactga cgatcgttgc taaagcagta gagacaaata aagcattccc gacaccccag
      961 ccggcacgta acccaatcag cattccgata ttcccagata atccgccaag accagcgaat
     1021 acaacgatga taaacaatcc tgtcatcaat gtttttttca aaccgatccg actagataag
     1081 aaacctgtaa atagcatcac cacaccagtg actaacatgt aactagtaaa taacagggtc
     1141 gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt ttaagattgg gtctactaga
     1201 cccactccca taaaagcgat catacaggta gctgctacaa ctagcgctga acttttcccc
     1261 tttgtttctt catttgtttg ttcttgtata tctatttgat tctccaatat ttccatccct
     1321 ttctctctat tagcatcata catgatttat tttacatgtc aatatgcaca tgtaaaacgt
     1381 ggaaacttta ctgtgatata ataaagaaaa taagacgaga ggtaggattt ttatgaatac
     1441 tttagcctat atattattat gcgtgctttt atccaaacca cgttctgggt atgaattgaa
     1501 gcagctgatc acaatttttt gggaagccca tcacagtcag atctatacaa cgcttgccaa
     1561 gttagaccag cagggttatg tgaccgtttt ggacaaagac gagcactctc aaaaaaagat
     1621 ctaccacttg actgatgaag gacgtgctct tgtagaggaa tggatcaaag aggaaactcc
     1681 cgctcctacg caaaaagatg aatttctagc aaaaatctat gctttttcga cgctcgataa
     1741 aacaacagct actggactgc tattcactag agaacaacag ctgaacaaaa tcatgcaaaa
     1801 aaatcaaaaa aaattgaatg acctctcgct agacaagaaa caagaatttg gacgttatgt
     1861 tgtgatccag cgcagaatta tgctttgtca gcaggaactc caatggtgtc agcaagtaag
     1921 agaacaaatg cagcagtttt ttgagtaagg gataaacaga acctttctag aaatatctat
     1981 tgaagagcaa attatcttca ataaaagagc aatacagttg gaaaagaaaa agcgatccga
     2041 acgacaggcc aaaacctatc gttcggatca ctatttttct agaactgcat tcaagagact
     2101 atgacaaaaa gcatgccaag gccttttttc aaataacagt gttccatcat tcattacttt
     2161 gaattgcttt tagcacactt cttgaaagcg ggccaacgat gatcaactgc aacggtaaag
     2221 cggcaatcac attcattttc caagcattca tataagcaga gaataattga tcaggtattc
     2281 cttgttccat gatcacaccg aataaagaca tacatgtcac cattcctaaa accatcaagc
     2341 atgaaatagt taagatcatt tggaccttgc tttctggatt tactggtagt ttaaaggcaa
     2401 tttttttcgc cagcacaccg atgatgaaga catccaaaat gaaagccacc acgaatccag
     2461 gcactagacc aatcaacaaa cttgataaat gaagatcttg atgcagccat aaattatacg
     2521 cgctcatccc caagaccatc aaaaaacaca tcattgttgt aaaaattatt ccttcttttt
     2581 tatttgtagg caatctgtac cactccttta aatttgtcac gaaaatcatc gtagcacatt
     2641 taaaaatttc tcgtaagtac tttttttatt ttctgccctt ttatttcata aacttcatca
     2701 gccgtacgct cgacaaagta agaatcatga gaagtaaaca aaatcgttcc cggatatatt
     2761 tgcattagct tctctaaagc ttcgatcgtt gccatatcaa taaaattagt cggttcatct
     2821 aacagcaaca cattacttgg cttagtaaaa agcaaagcaa tcgtcagacg ggtcgcttct
     2881 cccccactta atgtacataa cggtttcgtc aaagtttcct gagcaaaccc taagtgattc
     2941 agcaaactac ggacaagcga ttctgaaaac tctgtttgtc tcatgacaaa acgaatgatg
     3001 gattcttcag atgtcatttg ataacccttt tgctgatata cttgaaagct tactttcgga
     3061 gagagaagga ttccttctcc ttgtttgcgg atatgttcta ataaggttgt cttacctgaa
     3121 ccattttcac cgacaatcgc gattttttta cctaaagaaa actgaaaatc accatttacc
     3181 agtaatgttc tcccacttct ttccaattgg acattttgtc ccatgatggg atagcggctg
     3241 tggagttcaa gagattttgg tactggaaaa cggatttgtt tcatctgctg cggcttggtt
     3301 gtttctccta ttttttggag tcttctctct aatgttttcg cattcttttg gatggctttt
     3361 tgtacactgt ctttttgttt agaggaagac aaccgatcca gtctgatttg ttgctttttc
     3421 tttttactgg acactttttc caacttttcc gcttgttttt tcttttcttg gatcgatttt
     3481 tccaatcgtt ttttctcttt catgatcgac tctgcttctc gtagctgagt ctttttctcc
     3541 aattcctttt gagtgagata ggcactataa ttccccgaaa actctcggat ttctccgtct
     3601 tttacttccc agattttcga tgctagctca tctagaaaat agcgatcatg actaacaaaa
     3661 accagcgtac cataataata acgaagctct tcaatcagtc gatcaatact ttttctatct
     3721 agatgggttg ttggctcgtc tagaagcatc ccttgttcat aagaagaaag aagacgtatc
     3781 aactcgatct ttcgttcttc ccctccgctc catttccgct ctgaagtttc ttccagtctt
     3841 aactggaaat gactggctaa ttccaaattt aggtcctttg cttcagcgag ataggttaat
     3901 tgaggcaggt agttgaaggt gatctctgtt tggattttcc catgatcggg aaaaagttca
     3961 ccggctatta gtttgagcaa agtcgattta ccgacaccat tttctcctat gatccctata
     4021 cgatcttgct gatagacacg aagagaatca atagatagtt ctagctggtt gccaaagctg
     4081 acttgtagat ttgttatatt tactgctaaa ttttccatat gttttacact cctatttcat
     4141 gtaaaacaac aattatcgat actaaaaaag agcagaaaaa tctgtttgca aaaaaactgc
     4201 atcacatctt ttcctactct gaacgaaata actatgacta aatcaccaaa tctgtcatag
     4261 ctttcaccta ttctactgtc gttcgaaaaa atggacatac tccatccatg aaattgttgt
     4321 ttatacatgt cttttgaatt tatttagttg ttattcaaaa gttcgaaacg taatttcatc
     4381 gatgcagtca tttttccgac ctcctttttt attaggttac cacacacgat tcaaaaaaag
     4441 caatagctac tgaatagtaa ctgaaaacct tttattcgaa catagtgatc ttttctggtg
     4501 ctaaacgaac agactcgtaa ccttcttcta ccgcttttcc tattgataaa ataataactg
     4561 gaacataacg gtctttatcc aaaccaaatg cctctgccaa ctgatctgct tcgaatccac
     4621 caattggatt tgtttcatag ccatgatcac gcgcaactaa catgaattgc atagccgcta
     4681 agctagaatc gactttgact acatcgttca tttcttctct tgaaaaactc ttgtaataag
     4741 gaatgatcgc agctaattgt tgatctctga cttcttttgg catcttccct gattcgtaag
     4801 cttggttgta gatttcttcg ccatattcgt aacattgcat atcgccaaaa atcatgacca
     4861 ttgcagaaga agtatcattt tgtctcgtat tgaaacggat caaaggacgc aagatttctt
     4921 ttgcttcctc gctttcagcg accacaaagc gccatggttt catattgaca gaagaaggtg
     4981 cagtcgtcgc ttctttgatc atttccagca tttcttcgtg tgggattttg tatgtttcat
     5041 catatacgcg aacggatctt ctaccagtca taattgttga aaaatcattt ttttgttcca
     5101 ttattattaa cctctttcgt ttctgttgtt atattgcaaa gttgggtatt caatttatct
     5161 aaaagtgtta gaaattgttt catttctaca tcgctgaaag ccggggatag cacggaacct
     5221 gtatctttat ggtccatttc acaatgcttg attttcttct gggctttttc tgttagcgct
     5281 acatacactt cccggttgtt ctgaggattt ctctgacgcg aaacatagcc atttgcttcc
     5341 aataccttca gatgacgagt aactgctcct tgatcaatct gcaacttttc ttgcaaactg
     5401 ctttgtagca atggattttc ttctttcagt ctcatcatga tctcgtatct agtaagactt
     5461 ataccgatat tttcttcaaa gatctggacg attttttgat cggctaattt gatttgatat
     5521 aaaaggtgac taatctcttc taaagacata atttcctcct ttctaataat tgactcgtca
     5581 acgattgact tgtcaataat agaataaaaa aagaaaaaag tcaaagaatc agctgtgtaa
     5641 taaaaaaaac gctctcaata gaaaagtata gagaaaagaa attttttgta gaatgaacgg
     5701 aaaaaatgat aaagaaagca caacgctaaa accaagatta ttgattctta tcaaactata
     5761 gaagatagct cttctgcagt agataatttt acaccgccaa aaatttccga aatcgccttt
     5821 tgcaagaatc ccgtcgaata ttagaaattg gatcagtatg cttaaacagt aataaaaaag
     5881 ttatgacaag atgttgtcac aacctttttt gagtaaacgg tgttcaaaaa cttgcatctg
     5941 cggtaataag ttcaaccaaa caaaaaacat gaaaatctgt ttttgtttgg ctgttcttac
     6001 tacttgatgc agggcagctt tttcactacc tctttttaat aaccataaaa tcctattcct
     6061 tcatatctcc agcccatcgg tgttagccaa tctctttcct tagcactcaa ggtatagtga
     6121 tgggtaccag ttttttcatt tggattaaat agtcgataaa ttggcttgga accaccagaa
     6181 taaaaactta gaccttcata acgccaaccg atttttgtta aagagttgat ctcagattgt
     6241 gccattgtgt aatgatggtc tccactgtaa ggattgtata aacggtagac aggttgtccg
     6301 ctgtttggtg cttgccaagc aatcccttca tattcccagc ctacagttgg cagataattt
     6361 ttttctccgg cattcaatgt atataaatgt tctcctgtat gacggttata cagacgatac
     6421 atcggagaag ttgaagttgg tgctgtatca tactgtgtca gattataggt ttcgattaca
     6481 ttgttcaatg tagaaccata attaggcgca gtggcataac gacctgttag ccaagccgta
     6541 gcatctttgt aagagttcgt attgcttttc catgcaccgg aatagtagta aacgcctggc
     6601 tgaaaagaag tcgtcttcaa taccgttacg ttatcttgca atgattcttt gtacgaagga
     6661 tattttctaa aagcggcatt caccgtaatc cattgcccat tcacatattc cgaagtaggc
     6721 atcgtaacag attggccatt atagcttcct ttaatcccaa atagattgta attaggggca
     6781 gaagccaaag tactgttccc ccagccactt tcaacgatgg cttgagcaat catgactgat
     6841 gcatataagt cattggcact tgccaaactt tgtgcagttg aggcaatact atcaatgaac
     6901 gcttgttgag aattagcaga tgagcgagca taaaaagcat agccagtata gttttcgaat
     6961 tcagacaaat ctgcttgatg ggtatgtgtc aatgtttgcc catctgtcaa ttggttcgtg
     7021 atttcttctg cattctctgg attgttctga gcttctgctg atgtactgtc ttcggtttgt
     7081 gtttgttctg ttgtttcagt tgttggttct tcggttgaaa ttgtattttc tgagacagta
     7141 gctgactgca aagtactttc tgtatcgttt tcaattcctg tttctgaaga actcgatgtc
     7201 tgagttgcga cagtttctgt cgattcttca gctagcactg ttgtgttggc aactgctaga
     7261 tttcctaaaa gaataacgct aaataataaa ttctttgctt tcatcttttt tctcctttga
     7321 attatgaaac ttttcctaaa taacagtgta actaaaaaag taaaagcaag tcaatgtcca
     7381 tatttaaata acatttgttt ctttttaata aatttgcttt ttctgcataa aaagacgtaa
     7441 atgaagaata ttcttctcca ttcacgcctt aaattgatgg tcgtttgaat aactatttaa
     7501 caagtaattc tctctggata ttatccgtta tggattatac ttcctgtgtc gtcggacgga
     7561 taatcatgtt gctgacagac atccggtctg gcgtttctat cgcaaatgct acagcagaag
     7621 ctatatcttc agatgttaat ccccattctt tttgcgcttc atgaagttca agagcagcct
     7681 ttttgtcgct gatggtttga tataattcag tttgaacagc tcctggagag atgatcgtag
     7741 atttgatgtt attttgccgt tgctcttgac gtaatccttc catgattgca cggacagcaa
     7801 attttgttcc gcaataaacg gcggaatcag gataaacaac atgtcccgcc acagaatcag
     7861 ttgaaatgat atgcccagat ttttgttttt ccatgattgg aagtacggcg gaaattccat
     7921 ttaacacacc catgatgttg atatcaagca tattttgcca ttcatcacgg tgaccttcaa
     7981 ctaatggagc ggttggcatg attcctgcat tattgtacaa tacatcgatt cgaccgaact
     8041 tttccatcgc taaatcgata actgcttgga cttgtgcaaa atctcttaca tctgctgttt
     8101 gaatatatag ctcagcttct ggtaaagatt cttttattgc ttttaggcga tcttctcggc
     8161 gtgcagctat aactagttta gccccttttt ctgctaatag cttcgttgtt gcttcaccga
     8221 ttccgcttga agcgcccatg atgacaatca ctttttctga taaatcattc attctattct
     8281 cctcctgttt tgaaaaatct cttgcttata ctcactatct cttatttcat cttactgttc
     8341 aaataatccg ttcgacaggt ttgacgattt tggcagggat tcctgcaacg atggtattgt
     8401 ctgggacatc tttcgtaaca gttgcattcg ctgcaacaat ggcattctcg ccaatcgtta
     8461 cgcctggcag aatagttgct cctgctccga tccaagcatt tttcttgatg tggattggct
     8521 ttactgacaa gcctcttcgt tcttttggat cggttagatg gttcaccgtg atgaggttga
     8581 cacgaggacc aatcaatact gaatcttcta aacagatgcc acctaagtca acgaacatca
     8641 cttgacgatt gataaagaca tttttcccta tactaatatg tttgccgaaa tctgtataaa
     8701 aaggcagcag aacagtcacc gtatcatcta ctttgtcact aatgatattt tctagccgtt
     8761 tgcggatatc tgctggttca tggtacccag tattcagcgc tgctaaaggc tcttcgtttt
     8821 ccgcttggat ctgatggatc acttcaaaga gcggatccgt tactcgaatc tctttattga
     8881 cgatttgttt ttcgatgagg cttgtcattt tgctccctcc ttttatcctt actttataac
     8941 ggacggctta tgatgtctaa tacttataaa acatacttaa ctattccttt taactatact
     9001 tagtggtatg cttttttaaa aacaggaggg aaaaaatgga tattcgtata ctgacgtatt
     9061 ttttagcagt agctagagaa aaaaatatca gccgagcagc aaaatctctg catatcacgc
     9121 aacctactct ctcaaaacaa ctgaaagatt tagaagaaga acttggtgtg acacttttca
     9181 ctcgaggctc ccgagagata cagttgacgg attctggtcg atatctttat tcaaaaggaa
     9241 aagaaatctt gtcgttggta gaaaaaacgg cgaacaattt aacaaatgac gcaatcatct
     9301 ctggagaaat ctacattggc ggaggcgaaa ctaaagcaat ctctttcatt tctgatagcc
     9361 ttcattcgtt gatcaaggcg catcctgata tccagtttca tttatatagc gggaatgcag
     9421 atgatatcat agacaaactg gatagcggat tacttgattt tggactcgta atcgaaccga
     9481 caaacaaaca aaaataccag tcatttcgac tgccagccca agatcgttgg ggacttttga
     9541 tacatcggaa tcatccttta gcaaagcaaa cagtcatcca tccgcaggaa ctgaaaactg
     9601 ttcctttgat catttcccgg caaacgtcag tggacagtca actagctgaa tggctaggtt
     9661 tcagcataga tcagttatcg atcgtcggaa catataactt attgtacaat gcttctttga
     9721 tggtcgataa cgggactttt ggtgcattag ctctagatgg gatcatcaat acttatggga
     9781 cggaaaaagt attcatccca ctcgatccgc cattacaagc ttcactgaat ctcatttgga
     9841 aaaaagacca gcctctttct cctgctgctc gtaaattttt agatgtccta acggagaaat
     9901 acagttaagt agagtttttt tccttcgctt tcagcttttt aacaacgaat aagttaagca
     9961 aaagatccaa tgattaaata acataagttt cttaatttgt tccttccttt tatttctgat
    10021 aattccagta aattactata attataaaaa aagaattgac aaaacataac tgtctatata
    10081 aaattgatta cgttaacaat aattcgtttc atgtgactag atcatactag gcatgaaaaa
    10141 tctctgagga acatggtttc cctaggaggt ttttcgtgtc tatttttgtt tggccgcaat
    10201 caactggtct agcaaacgtg aaaaccaaat cttcaaaaag ggtgcgcgca tgaaaatcaa
    10261 aaagatcttt aatcaaaatg cagtattggt agatgacggt ggacaggaaa aagtagctat
    10321 tggaaaaggg attggatttg acagaaaaag aaatgatttg atttttgatc gtgatgtcga
    10381 acggatattt gtcatggaac cagaaggtca aatcaagttg caaaatttac ttaatcagat
    10441 tgatgaacgc tttttatttg cagcagaaac gatcattgat catgcggaaa ctgttttgat
    10501 ggaaaagttg aatgaacatg tattgatcgc tttgaccgac cacattgctt tttctgcgga
    10561 gaacattaat aacggtatcg tcatccgcaa caaactttta agagaaatcg aagtgcttta
    10621 cagtgatgaa ttcagtattg ctcaatgggc agtagagtat ctgacaaaag agcttgggat
    10681 tccatatact tatgacgaag caggatatat cgcaatccat attcacagcg gacgaagcgg
    10741 tcggaacaat aaccatcgca gtatccgtga agtgacgatt gtatctgaca tcatccattt
    10801 agtggaatca gaattggaaa cagatatcca ttcagaacca ttttcactga attattcaag
    10861 actggtgaat catttacgac tgcttctaca acgaacccat gcgcaacaat atgctgtttt
    10921 agacacggaa atcgtagaaa tggtcaaacg aaaataccca gaaagctata agatttctaa
    10981 aaaaatccgt gtgttgctga ccaaagaata ccagctcgcg atcacgaaag aagaactggg
    11041 ttacttggcc atccatatcg agcgtttaag aagcgcaatc gtacaaacaa atgttaacaa
    11101 tcatgaggag gaaaaaaatt gaaagcatat ctacaacgaa tgggacgttc ccttcaactt
    11161 ccagttgcgg tcttacctgc tgctgcttta ctagtaggga tcggaaactg gtgggcatct
    11221 tatagtaacg acattgtcgc tcatttttta caagctggcg gtaacgcagt tttaggtcaa
    11281 ttacctttgc tgtttgccgt tgggttagca ctagggatgt cagtggacaa atcaggtgct
    11341 gctgccttgg caggtttggt cgcatttgaa gttccagtaa atgttttaaa aactgattca
    11401 gtagctactt tattgaatat caaaccagaa tcagttgatc catcttttgc tcagatcagt
    11461 aacgtattta ttggtattat tgccggattg attgcggcag ctctttataa tcgtttccac
    11521 gaagcaaaat taccgatggc tttatctttc tttagcggca agcgtctagt gccaatcttg
    11581 gctgcctttg tcatgttgct gatcagtgca gtgctactgc tcgtatggcc tccggtttac
    11641 tctgctttag tttcttttgc taaattcatt ttgagtttag gctggggtgg tgcaggtctt
    11701 tatggcttct tcaaccgttt actgatccct acaggattgc atcaagcaat gaactccgtg
    11761 ttctggtttg acgtagcagg aatcaatgat attggtaaat ttttggcttc tgaaggaaca
    11821 aaaggcgtaa caggaatgta tcaagctgga tttttcccaa tcatgatgtt cgggcttcca
    11881 gcaggagcat atgctattta cagaaatgca cgtccagaaa acaaagcaaa aacagcttcc
    11941 ttgatgttag cagcagcttt tgcttcattc tttactggtg taacagaacc acttgaattc
    12001 tcatttatgt tcgttgcttg gccattatat gtcttgcatg caattttcac tgggatttct
    12061 ttagcagtga gtgcattctt ccattggaca gcaggatttg cctttagtgc cggatttgtc
    12121 gattacttcc tatctttgaa aaatccgatt gcgaatcagc cattgatgtt gatcgtccaa
    12181 ggattagtaa cagcagtgat ttactacttt ggctttaact ttgctatcaa aaaattccat
    12241 ctgatgactc ctggccgcga ggaagcagat ctttcagatg acgatactgc aacgactaat
    12301 tcagacaata aatatgcggc acaagcaagc aaaatctacg ctgcattagg cggagccgac
    12361 aatgtaactt cgatcgataa ctgtactaca cgccttcgtt tgcaagtcaa agatacaggc
    12421 ctgatcgatc aaaataaaat caaagccact ggcgtacctg gtatgaagat catcgacgga
    12481 aaaaatgcgc aagtcatcgt aggtacagaa gtacaattcg ttgcagatga gatggcaaaa
    12541 ctacatggtg gtgctgcaac acgacctgca caaacaaaca ccgtggttaa aacagaaaca
    12601 tttgccggtg gaacgatcga acaagatatt tacgctatcg caaatgggaa actgattcca
    12661 atcactgaag tttcagatga tgtattcgcg gaaaaaatga tgggtgacgg ctatgctgta
    12721 ttaccagaaa atggagaaat cttctctcca atcgctggta cgatcacaaa cattttccca
    12781 acgaaacatg ctgtcggaat ccaaacagat gctggtatcg aagtcttgct tcatatgggc
    12841 atcaacactg ttgacttaaa aggcgaacca ttcactttat atgtaaaaga aggtcaaaaa
    12901 gtcgcaagag gtcaattgat tgctttagtt gatcttgccg ctattcaatc tgcaggcaaa
    12961 aacacggata tggtcgttgt attcacaaat ggcgacaaag tccaaagctt agaaatcgaa
    13021 cccgcacgtg atgtaaaagc aaatgataaa atcggctctg tttccaacaa agcctgagcc
    13081 atcgtcttcc ccagactttt ttatcgataa acaaacagga gctgagacaa aaatcttgtc
    13141 tcagctcctt tttccgaata aaaacggcgt tctcctgcca actccgcggt aataagtcca
    13201 gccaaacgta acatatgaag agctattttt tatttgactc ttcttattac ttgatgcaga
    13261 acagcttttt tacaacctct gataaacggt gttcaaaaac cagtttatcg gtatgaagtc
    13321 aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttcata ctcaaaacta
    13381 atcggctttt tcacaacctc tttatacatt attcctgatc caatatttct tttaatgctg
    13441 cttcaagaga agttaatggt tttcccaata ctttttctaa atcatcagag gaaatagcta
    13501 actgatcctt tttaatatca tgttggatcg ctaaaaacat gtcagctgct tcttgaggga
    13561 atccggcttc ttttagattt tcgacaaacg ctgcatcact tgcttcaata atttctaact
    13621 ttttacctgt cgcacgctct aatgccttgg ctaattcttc atagtcagtt agattgccgg
    13681 ataattctaa gatttctgga gagtcacttt ctactagtac ttttgctgca gcttctgcat
    13741 attcacgttt caatgcccaa cctgtttttc catttcctgc agcataaacg aattgaccag
    13801 tttttaaagc ctgcccaatg ataggtaatt cattctctac ataccaatta ttccgtaaaa
    13861 atgtatggga aatacctgaa tccttaatca ttttttcagt gaattggtga tctggcgcta
    13921 atacactgat cgagtgatcg gcatctgcaa aacttgtata agcgatataa gataccccag
    13981 ctgcttgtgc tgccttcact acattcttat gttcggcttg acgatttcct ggaacgccag
    14041 agacaaaaag caatcgatct attcctttca acgcttcttt cattgagtct aaatcatcat
    14101 aatcaccaat acgtatatta aatccagctt ctttcagtgc ttctcctttt tcttcactac
    14161 gtactagtac atagatttca ttttgtggaa ccatcttttt taagaattcc agcgcataac
    14221 caccaaaacc tccagttgct cctgttacta aataatgcat atttgccact ccctattctt
    14281 tttatttgtt aagatttaca gctgtacatt tataaattac acctttatca taaagagtgt
    14341 ggtaagataa gtcaagcaaa aaaaatgaaa ggatgacaac tgatgaagta ttctctgcaa
    14401 tttagtgatg caatccatgt acttgcctat attgaaatgt ttcaagatac ccgatcactt
    14461 tctagtgaga tgattgccag tagtatcgaa acaaatgcag caaatgtacg taaaatcatg
    14521 agtcagctca aaaaatccgg tttgatcttt acaaaaaccg gaaaaccgca gccttccctt
    14581 gccaaaagtc cagatcagat ttctttacta gatgtctatc gcagcatcga aggtaataca
    14641 cagcttatcc aagtcgatcc aaaaacaaat ccaaattgcg tcgttggtgc gaatatccaa
    14701 gaagctttag aagaaagcta cgctcggctg cagaaaaagg cagaagaaga aatggctaag
    14761 atcacacttg atagtctgat acataaaata gccgttttgg aaaaagaaaa aagaccagaa
    14821 aacacaggcc tcgtagagag atttttataa ttctctctac tgtgcctgca tttttctgat
    14881 cggaatcgtc tacataaatt cttttattct ccgggggaca aaagccttgt catgcccctt
    14941 tttcctctct aatgctcagg tcaaagcgct gaagtcatga cgtcttgata aacggtgttc
    15001 aagtagctga ccctcggcat tagttctgaa aaatgcaaaa tatggaaagc tatttcccat
    15061 ttttcctctc taatgctcag gtcaaagcgc tactttcacg acctctatat tatcatggtt
    15121 tattgactac cggtatccag atttctccca tatatttccc gttggtaact cccatttcga
    15181 ctacagcatt tggaccccca acataggcgt aatcttctac ttctcttaaa acatgcccaa
    15241 aggccgtatt cgtcaaatca tttcttaatt cttcaggcga ttctgctaaa gcgattacaa
    15301 caagatacgt tccttttggg aatgggatga ttcgggtagt gtttggaaca tcctgactcg
    15361 tttgaacacc gacatagtac atcattttcc cgttataggg ttcgttgact gtaaagaaat
    15421 aatgattttc agcagcttgt ttcaatgcat ctattgttcc attaccgata actttttgct
    15481 caaatgcttg tttctctgca gccaaaccga caaaatccgt attgctactc ttcaattcca
    15541 caccaatacc cgtcaccgta aaatctggtt tttcttcgat cctatacttt gccatttctc
    15601 ccaccctttc tattatatta agttcatctt acataaaatt aaagggaaat gacacgatta
    15661 cgctcttttt tctagggata tttttatttt ttaactattt ttttgctttc actgcaatcc
    15721 aaatctcact gtaaacatta ctgaaatcct ctccccattt tgtaaaagag atctcgggag
    15781 cttcgactaa ctcataatct gaagaaggaa gccattctgc atagattttc ccccaagtat
    15841 cttgtaaagt ttggggaaat ggccctttat taggaaaaat ggcccaagtg tgttcttcta
    15901 tagcaagcat ttctaaatca gcgtacggat tttcttttgt cgtagcaaag ccaatcatgt
    15961 gcatcaaact gcccttttct tccaagcggg ctccatcaaa tccataagaa acgttgatta
    16021 cttgatttgg atataaatct cctaacttat gcatctcttc cctttgagtc tccgtgatcg
    16081 tctgcgctaa cttttgtatt tcttgattga ctccttcaaa tttgacagga acttttttcg
    16141 ccacacctgc cacataaaac tgttctttct tttcgatacg aaattccatc gattttcctc
    16201 ctctgacatc aataaaaaat gtcaagcgtg gaaaagattt ttgtatgccg tatctgctga
    16261 tttctgaagg cagatatcct gaccaatcac gaaaagctct tgaaaaacct tcgactgttt
    16321 catatccata tctaaacgcc gtttctgtca ctcttgatcc atctaggaga tcgcgattag
    16381 ccaaagccaa tctacggttt ttgatatagt ccattagcga catccctgca ataaacgtaa
    16441 agatgcgttt taattgatat tcagagattc ctgtattttc ggctattatt ttataggaaa
    16501 gtccttctgt caaatgttct tcgatgtaat cgatcaattg gttcagatct ttaagcatat
    16561 ttatcttcct ccttgcttgc ctttttatca tattatcaaa gaaagtcaat tacttgatga
    16621 atcaggaacc aatttagtca gatgtagaaa atgttgtatg gatctaaaga aaattctcaa
    16681 gcagcgtttc gtaacggata attggtatta tctgcctatc tatgttttac ctttagaaaa
    16741 ataaattttg gggaagacac attctaagta aacaaagcgg taaaaatatc ttttattccc
    16801 ttagttaatc cgcttactac ctactgtaca aagcaaattg ttgttcaaac tgctgatcag
    16861 aacgctgctt ggatttttct ttgcgataca tcatacctct tttatcaatt ggaacaatta
    16921 tttatttcta acaaaatcac ttcatttttg tcagataaat aaaaaacaaa aaaagttcca
    16981 tctttaaaac acgctattct tttacttttt ctcacattct ctaagaaaag aaaaggagaa
    17041 tgaatttttg acaattcgag caaaagtgat tatcaaatat gtaaaatcag ctactttttt
    17101 cttaaacgtt tctttatact aaatataaat aagtgtttca tgaaaggaga actagatgaa
    17161 taattggctt gagtattttc ctgaaaacgt tttggaacgc ggttacagct atcatctgca
    17221 cggttttgtc cgtcatttga actatacaag caagtacttg tccgcaacag tttctggcac
    17281 ggaagattat aaggtagtga tcacttggga tgaaaagacc aacatgactt gtgattgtct
    17341 atatgccata gaaggaaaaa aatgcaaaca catggctgct gtcttattcg cttacgaaga
    17401 acgtccaata aaaaaatcca actactcact ttccgaactc tcgtcccttg tttcctccgc
    17461 tagttcctct cttgtacggg agcttttaac agagattctt atagaacatc cgcaatttat
    17521 cgaacgcttc aaagttaaga tgccatttca tgcaataaat tattcagata aattaacaac
    17581 tatcatccat aaatacgatc atattatcaa gaaaaacaaa aacaggaaaa cagcgaagtt
    17641 catcatggag atgcgaaagt tcatccaaga agcagttgaa tcgctcattc agcaaaatgc
    17701 ctatcttccc gcattcgaat tgatcaatga agtgattgct actctcgaaa cattctattg
    17761 ggagcctgag gatgaacgaa cccttcttct gatagaggac tgttattatt tatggaaaga
    17821 attattagca gaagcacctc atgcagaaaa aaggcaaatg ttctcttggt tcgtctgcca
    17881 agtcgatcat actgacgcct cttattcaaa acgctactcc ataaaaatcc tgaaagaaga
    17941 ctttcgggaa aaagaatttt ctaaccaaaa gaaaaaaata gataaaaaaa ctaaagaaac
    18001 ggtaaagaaa gacgatttca atgaaaaata gcaagtaaac gataacaacc atcctaaatc
    18061 cacaagaaat acagcagacc ttgctttaaa aacacgaatc atgcaaagga tgaagtaaag
    18121 aagacttaac gcgtacccaa tattagtcat ttgactatta ggtacgcgtt ttgttttata
    18181 agtcatgaca aatttccttc gttgctgggt agattttccg gcattgttga tagattttat
    18241 gatacttttc tacattttgt aagagaggtt ccactgcatc tgtatattgg ataaaattct
    18301 gacaacaact ttcaggtgtg tcgaaccact ctaatcttta aagataaata ttaaaataac
    18361 gattaataat attaacagtc tttatttttc accaccaaaa acctatcttt gcatatacta
    18421 aatagacgta tatacacaga taggtttgtc ttgtgaaaaa taatgattat ccttaccaaa
    18481 aaatgtttgt ttttctacat gttcgtactt atcaaaaaat atgatcctta ttgaaattac
    18541 tggctattta tattccaacg acttcttgtg ttaatttttg ttatctcata gtaaattatg
    18601 tttcattttc acttaattta gttgtcacgt gttcgtcaat tcgtaaaaac ggtaaatata
    18661 taaacacact tgcggctata attaatattt gtaaaacagc tgctcgccag tctccggctg
    18721 ttgctaaaaa tcccgatata actggtggcg tagtccaagg aatttgcact actacatgat
    18781 taattaatcc cacagcagtt gcaaaatatg ctactgtcaa agaaaaaatc ggtgcaagca
    18841 caaagggaat aatcagactg atattaaata caataggcaa tccaaaaata ataggttcgc
    18901 ttatattgaa tatagcggga gttaccgata atttagcaaa gtccttataa tcttttctac
    18961 gactgaagat aaatattgca atcaataaag caatcgtatt tcccgatcca cccattaccg
    19021 caaaggtatc tttaaaggcc atattgataa tatgtggaat ttgctctttg tttgcataag
    19081 ctgccatatt ttcttgcata ttctgaatca aaaacggatc taacaatgaa cctgatatta
    19141 ctgcttgatg gataccaaat ccaaaaaata gattagcaat agatgtaatt aacaaaaatc
    19201 ctggtaaacc agttgtaatt ttacttaatg gctctgtaac tatcgtggta attagcttat
    19261 ttatatccat attaaacaat tgaatgatta taaatgacaa taaagcaaac gaggtaatcg
    19321 taataatgat tgggattaat acattaaaag actttaaaac agcgggagga atatttccgg
    19381 atagctgaat ctgtagtttc ttattattag aaagtttaat aaataattct gtagccgcta
    19441 atccaacaaa tatacctaca aacattcctg aagctcctgt ataggatata ggtatcacac
    19501 ccgtcacttc aacagcttta tccgcatttt caggagtaaa catcatctgc ataggtgtta
    19561 atacaacaaa tgtcgaaata gcaactaata ccgctgcaat atgatttgta taatttctgc
    19621 ttgcacacat atgataagat actgctgcta caactaataa tgtagttatg cttaatgtac
    19681 cattggcaat tgaagtacca atttgttgta acgtggtcaa tgtactagta tcgacaattt
    19741 cccccatgaa tcctgttggt tctaagatca ctgaattaat aagtgtcaca aatcctgcta
    19801 acatcataaa tggcataaat gtagcaaacg catctcgcaa agttcttaaa tggatctgat
    19861 tccccaactt agtcgcaact ataccaaatt tttcaaatac aatgtccttc ctgctacttt
    19921 tgcccatatt ttttctcctt tatgcttatt gtaatcgatt actttttcca cccaaataat
    19981 acatcactta tcaaaaaaag taaatacttt taattaaata tatatatctt ttttagtata
    20041 aaaaaataag ctctgaaaaa ataattttcc cgagcttatt tttcaacaaa aacagcttca
    20101 aaaacaaagt cttgatataa atgtctcgat accgaatact cgaaaggttt accagacgat
    20161 agagcaacaa ctttgtctat ctcaatcata aattcacctg gatctatttt taatattttt
    20221 gcgtcaaatt cattcgcagt atctcctttg atacgtatgt gcgaagtctt tatttccaga
    20281 cccagttcat ttgtgatata agcatataca gatttcttta aatgttttgg ttccaagcct
    20341 ggtatgactg ctaatggcat gaatgtttgc tcaatcgagt atggttgaca atcaataaaa
    20401 cggcttcgta caatattata tacatagtct tttacactga tacttaattt atcagctact
    20461 tttttcgatg gaagttcaat tgagaaagta tggatttctg aatctacgtg ttcttcacca
    20521 accacgctaa acaaaccttc gtttggacca agaactcgtg agttatcaat tggtgttctg
    20581 acgacttcag tcccataccc acttctactt cgcaaaactc cttcggaaac aagtaagtct
    20641 acgcctttct ttactgttaa cttgcttgta tgataaataa ctgccaattc atctcctgta
    20701 ggaagtttct caccaatttt atactctcca tttacaattt ttttctttat atctaagtaa
    20761 atttccatat acttcgcaat ttttttcaat ggtgaccctc caatcaaaaa catatcttca
    20821 tctatacttt aacataaata aaccgataaa atccacatca aaattataca cacaataaaa
    20881 aagatatata tatttaaaca aaactattta ctttaagttg taagcggtgt tatcattaag
    20941 tggaaacagg aggtaaaaaa attatgacaa ctatgaaaaa gctaactttt ccagatgatt
    21001 tttggtgggg ttccgcttgg tcagctgagc aagcagaagg aaaaggagaa acaggaaaag
    21061 cagagactat ctgggatcgc tggtttaaag aacaacctta ccggttttat caacgaatcg
    21121 attcctctat tacaaccgat cacatccatc aatataaaga agatatagaa ctaatgaaaa
    21181 aaactgggca taactccttt cgcgtttcta tttcttgggc acgaatgttt ccaaatggcg
    21241 gtaccggaaa agtaaatccc aaagccattt ctttctatcg aaaattattt tccgaaatga
    21301 ataataacgg aatcaaagta tttgccaact tatatcattt tgacatgcct gctactcttc
    21361 aagataaagg aggatgggaa tcacgtgaag tagttgatgc ttatgttcat tacgctgaaa
    21421 cttgttttaa agaatttggt gacttagttt gtcattggtt taccttcaat gaaccacttg
    21481 ggcctatttt aggtacttat cttgaagatt ttcattatcc aaacctcatt gactttaaac
    21541 gcggagcgca agcagcattc ttcactatac ttgcacacgc aaaagcaata caagtattta
    21601 aagaactagc tcttcctagt aaaataggcg ttattctaaa tttgagtcct acttttcctc
    21661 gtagtcaaaa tcctgctgat gtgaaagcag cagaaatcgc tgatttattt tatacgcgga
    21721 gctttttaga tcctatggtt aaagggaatt tttctaaaaa gcttatcctg ttattacaag
    21781 aatataatca gcttcctgaa gattatacga aagaagatct tgtatgtatc tacgaaaata
    21841 ccgctcaaat tcttggacta aactattacg agccacgtcg cgtcaaatct cgttcttcta
    21901 tggtggatac atctagtcca tttttaccag agtggttttt cgaaccacat atcatgcctg
    21961 gacgacgaat gaacgaatac cggggatggg aaatttacga aaaaggaatt tatgatttgt
    22021 gcatggatat caagaaccat tatggaaaca tcgaagcatt tatctcggag aacggaatgg
    22081 gcgttgcgga tgaagaacgt ttcatggatg atacagggca aataattgat gattatcgga
    22141 ttgagtatat caaagatcat cttgcttact tatggaaggc aataaatgaa ggatgtaaca
    22201 ttaaggggta tcatctttgg acatttattg attgctggtc atggatcaac gcctataaaa
    22261 accgatatgg gctggtttca ctcgacctta ctactcaaaa aagaacaatt aaaaaaagtg
    22321 gcgaatttta caagcaatta agtgatacaa atggatttag atacgatgta gacttgttag
    22381 ttgaataata ttctaaaatt ccacttgaag tgaacacatt agaaaacaag aataatgaga
    22441 aataccaata acaaatactt tttcttcata cttcatttat acttgtcagt ataagagact
    22501 gtgacaaatg tagtgatcct cagaagttag gtctggaaat ctaacttgag aagatttttt
    22561 taaactacgt ccagtctttt ttatttgttt aaaattgaag ttgacaagtc ttcattaaaa
    22621 atttagaata ttcacaagtt tgacgacaat tatgaaaatt tatgtcgtgc taaaggagtt
    22681 ttgttattgg atgaaaagtt agatataaaa actgcgatca aagacacgtt acctaccgtt
    22741 tttggttata tcggtattgg acttgcattt ggtatcgttg ggaaagctgc cgggtttcat
    22801 ccgctggtcg tcacgttgat gtccctgctg atctatgctg gttctgccca atttatcacg
    22861 gtcagcatgc ttgctagcca tagtccactg ctctccatcg ttctctcgac ctttctagtc
    22921 aattcccgaa tgattctgat gagtatgacg attgctcctt atttcaagaa aaatcggctg
    22981 cttcaaaatc tgctgattgg cacattgctg acagatgaaa gtttcgcact gggaatgaat
    23041 aaattgaact atactggaca aaagttaaac tttcgttgga tgaatacagc taattggatt
    23101 tcttatttga cgtgggtggg ttcttctctt gttggcgcac ttttagggaa ttttattact
    23161 gatccgaaaa agtttggttt ggatttcgcc atcgtcgcta tgtttatcgg gttactttat
    23221 cttcaagtca tttctgatag aaacacctct aaacgattac agttgatcct gattggtctc
    23281 actttgattc tggtatatgt cggactgatt tttatcccaa gtaacttagt gattttagtt
    23341 gtaacactga ttgggtgcgg attgggggtg tggatcaaac atgccttctt ttgagtttac
    23401 attgctgact attttaggtt gtactttagc aacttggctt tctaggatcc taccatttgt
    23461 cttactgaaa aaattcgatt tgccgcaacc gttgcttgag tatttaagtt ttgtcccgat
    23521 cgtcattatg tctgctttat ggttcagcag tctatttacc caaaatatcg gacatctgcc
    23581 gcagatcaat ctcgaaaatg ctttggcttc agttcctaca cttttagctg ctattctttc
    23641 aaaaagctta ttggtgatcg tcttggtagg aattctttcc ctttcgttga ttcgcttatt
    23701 ataaataaaa aaacaagagc ttatggcaaa ttactgtcat gcgctcttgt ttttatcaaa
    23761 gtcaaataag aaaaaaatcg gcgtattctt gcttatccgt tgaacggacc actaacaacg
    23821 acttttccta atatatgtcc tgtttctacg tctttggttg cttgtttcaa gttcttcgca
    23881 ttcatcccat ctgaatagac cttgctcaat gtactgcgga taatcccttc atttgctaaa
    23941 gcagcaatgt gcgctaaagc ttctccttgc gtttcgattt catagttata gtctgtttta
    24001 gcgaacatat actcccagtc gaagctgata gattggtttt tccaaacacc tatatctaac
    24061 ggctctttga tccctacgat cgttcccaca tgtccaaatg gtcggacaag gtgtttgatt
    24121 tgatcaaagt agcgggtaat atcgaataat acagcgacat actctacttg atcgattcct
    24181 aattcacgaa aacttttact taagtcgtga tgataatcga ttggatagtc tacacctgtt
    24241 tttttcagcc attcaaaatt cttcggactt gcagtcgcgt agacttctag gccagcccaa
    24301 tgcgctagtt gattcaaaat cgaaccgacg cccccagctc cgttgatcac taagattttt
    24361 ttcccgcggt tggcattttc ttctggagtc agaccaaatt tttcaaataa caattcataa
    24421 gcggtcaatg aggtcaacgg caaggctgcg gcttcttcat ctgaaagatt ttttggtgca
    24481 agagcgacaa tacgttcgtc aaccagttgg tattcttgat tgcttcctgc tcttgtcgtt
    24541 gtacctgcgt aaaaaacgcg atcgccgaca gaaaattttt gcacttcatc acctacagca
    24601 acaactttcc cgactccatc aaaccctaag atacgtaaag catttcttat cccgttatct
    24661 tggcgaagtt tcgtatcgac aggattaaca gatactgcgt tgacttttac cagaagatcc
    24721 cgtgaactgg gtacaggtat ctgttctttt tcatcaataa agctttttgg atcatcgatc
    24781 gacaaccctt cataaaaacc gactaccttc attaattcct tttctgacat acgaattcct
    24841 ccttagcttc atcaagttgg agcatccata cagttttcat ttcaatatat atagtatgct
    24901 atttgttcca cttttattca tcataattat tctcttactt aaagtaaact atttgcactt
    24961 ttttggttaa aaaagaggtt gcgacaagac ttttgtcaca acctctttta aacggtgttc
    25021 aatcaactga ccctcggtat tcgctcaaaa aacgacaaaa tatgaggagc tatttttgtt
    25081 tggctgttct tattacttga tgcaggacag ctttttcacg acctctaatt cacggtgttc
    25141 aagcaagaaa tcattgttca ctgaaaagcg ttggatgttc tttttcaaag gtgtctaaga
    25201 tctctcgtac ttcatcagta gatttcgtat tcatcaactg aactcgcaag tcatttgctc
    25261 ctggaaatcc tttgatatag attttaaaga aacgatgtag tcctgtgatg gaacgcggga
    25321 tgatttctga ataatgatct tgcagatcta gttgcagacg aagtagtccg atcagttctt
    25381 tttctgtatg ttccctcggt tctttttcaa atgcataagg attcttgaaa atcccccggc
    25441 caatcatgat gccatctacg ccatattttt cggccaattc ttctcctgtc tggcgatctg
    25501 ggatatctcc gttgatcgtg atcagtgttt gcggagcgat ttggtcacgt aaagcaatga
    25561 ttttagggat gacttcccaa tgtgcatcta ctttactcat ctctttacgc gtacgcaaat
    25621 ggacagaaag attggctata tcttgatgaa gtaggtgact gatccattct tccatctcag
    25681 acatttccgt atagccgata cgcgtcttga cgctgacagg caaaccgcca gctttagccg
    25741 cttcaatcaa ttgtgccgct acttctgggc gaaggatcaa gccactgcct tttccacgtt
    25801 ctgctacatt agggactggg cagcccatgt tgatatcgat tccttggaag cccatttctg
    25861 ccatagcaat gctcatttct ctaaaaaatt ctggcttgtc tccccaaata tgggcaacca
    25921 tcggctgttc atcttctgta aaggtcaatc ttcctcgtac actgtctttt ccatctggat
    25981 gacagaaact gtctgagttt gtaaactcag taaagaagac atccggtgct gctgcatgct
    26041 ttacgacatg gcgaaataca acatctgtta catcttccat tggtgctaaa acaaaaaaag
    26101 gctttggcag ctctttccaa aaattagtag tcatttattt gttactctcc attctatcaa
    26161 gcagtgaagt cgcaatcttt ctcaaaaaca ttgtcattat actaggaaac aaaaaaagaa
    26221 gcaaagtgaa cagcttaaaa gatgtttctg attgagcaaa aaaagactgt gacaaaaatc
    26281 ttatcacaat tccttttccg gaataaatgg tgttcaaaag cttgcatctg cggtaataag
    26341 tccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
    26401 agaacagctt tttcacaacc tctccactaa acggtgttca atcagctgac cctcggtatt
    26461 agctcaacaa acgacaaaat atgaggaact attttcccgt ttgtttctct aatactcagg
    26521 tcaaaacgct gatttcacaa cctcttttct aacttctcaa tcctcttcct ttattgatca
    26581 aataccaagt aacggcgtac aaaacaacga tgaatagcac aagtacgatc atcgatgttg
    26641 ctactggcac atcgattgtt ccaaggaatc cgtaacggaa accgaagatc atataaacga
    26701 tcggattgac tttcgaaaca gcttgccaaa atggcggcaa catagagatg gcatagaaaa
    26761 cgccacctag ataagttaac ggctgcaaga caaatgtagg cacgatcgat acatcgtcat
    26821 aagactgagc aaaaatcccg ttgagcagtc ctgctaacga aaacaagatt gccgtcatca
    26881 ataatgtaat gatgaccatg aaccatgaat acacatgaag tggtacaaag aacaaggaaa
    26941 tgatcgttac gagagagccg acgagaatac tgcgacccac tccgccaatc acaaagcccc
    27001 aaatgatcac atgcgtagga acaggcgcta ccaagatttc ttcgatgttt ttctggaatt
    27061 tttgagagaa gaaggacgaa gaaacgttgg catacgaact agtgatagca gacatcataa
    27121 tcaaaccagg cacgatgaat tccatatatg aaaaaccacc catgtcaccg atccgaccac
    27181 cgatcatttt tccgaaaata acaaagtaca aggatgtcgt gatcacaggc ggaaccagtg
    27241 tttggaccca gatacgcaaa tagcggttcg tttccttgat agctaaactt tttaatgcag
    27301 taaaataaag attaaacatt tttctcctcc gtatgattat tttcttctgt gattttcaaa
    27361 aacagttctt ctaaacgatt cgacttattc ctcatagaaa gaactttgat tccttgtctt
    27421 gtcagctgat cgaagattcc gttcacccct tgatttcgtt caacttcgac agcgattgtc
    27481 tgttcatctt caaatgtaca agcgtatcct tcaatcacag gtttggtctc atatggcgct
    27541 aaatcaaaga taaatgtttc aaattgcagt ttggatagaa gctctttcat actagtattc
    27601 tcgatcagtt cacctgattg gatgatcccg atgttgcgac aaagcatttc agcttcttct
    27661 aaataatgcg tcgtcaaaat gatcgttgta ccattttcgt tcaattctcg gagaaactcc
    27721 cacatctcgc gtctcaattc aatatcgact cctgctgttg gttcatccaa gatcagcaaa
    27781 cgtggttcat gcatcaatgc cctagcaatc atcagtcttc gcttcattcc cccggaaagc
    27841 atacgtgcac ggacatttct cttttcccaa agattggact gcttcaaata tttttcgctg
    27901 cgtttcatcg cttctttgcg agagacaccg tagtagcctg cttgattcac gacgatttgc
    27961 tggaccgttt caaagggatt gaaattgaac tcttgcggga ctaatccaat ctgttgcttt
    28021 gctcggacta gatccgtatc cagatcataa ccgaagacat tcacttttcc agatgtttta
    28081 ttgactaaag aagtaatgat tccgatcgtt gtagacttcc cagctccatt tggtcctaat
    28141 agcgcataga aatctccttc tttcacggaa agatcgattc ctcgcaatgc ttcgacccca
    28201 cttccataaa cctttttcaa attatttatt tcaagcgcat ttgccattta tttcctatct
    28261 ccttatagac atgattcttt attgtatcat ggaatacagc agatgaaaaa acaacttggt
    28321 tccagcgaaa aatcaggttg ctgggctcag gaaaatctcc taatgaaaga catcaatcgg
    28381 acgaagtcag acaacctttt cagaaaaaac aaatcgaaga taaaggatta ctattcatat
    28441 gtgcaacaaa aggagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    28501 gtataaacgg cggaagcaaa agccaagatt tttgatccaa taaatacttt cgatcacttc
    28561 gcctatccca atacatgcca ctgccgcttt tcatcaaata acgcggcttc cgtttttgcg
    28621 gtttctacta aagtctctgg gtaatccaaa actttcagca aggcaatcgc atttcgggtc
    28681 cttgaaggtc cttcttttaa tttgaaatca aaactgattc cttttccttc tgttacttgt
    28741 tcttcaaagt ggacattctc acaataattc tttaaaatct ctgtcaattc gatatcatgt
    28801 gtggcgacaa atgctaaaga tggatactcc gcaagccacc gaacgactga agcggaagaa
    28861 gcaatccgtt cgatcgtatt tgtccctttt aaaatctcat ctacgaagca gtagcagcgt
    28921 tctttggaag ccacttggtc caacaaacgt ttgatcgatt tgatttctga aacaaaataa
    28981 ctgtcgcctt caaataaatc atcttcgatt gccatggaag tcaacacatg tccaggttgc
    29041 agggtaaact gttctgcaat cgctgtttgg atcgtctgtg ctagaataca gctgatggct
    29101 atacttttga catacgtaga ttttcctgat gcattggaac ccgtgactaa tgtattcttc
    29161 tgccagttga ccggattcac taccgcttct tttaacaatg gatgatagat atctttcgct
    29221 gtcacaccgc cctcagtaaa ctctggtcgg caagtgatgg gcatataagt acggtaattc
    29281 aatattgcag cggctacttc taattctccc agcaattccc acagcttgat ggcttcagtt
    29341 gaatgctttt ctaatttagt gagaacgaaa tgataggaga taaatggcag catgaacatg
    29401 atgttgacat attcaaaaat caactctgct tcactcccac tcttcatacg aaatgaaaaa
    29461 cctaatttag ggatgtctct taatggttta gtttgctgtt tcagctcttc ttgaagtggt
    29521 gtcggcagtt ttgctagctg attggcggct gaaatcgttg aaaccaaata actcatgcta
    29581 ttcagctctg tttctagtgt ttgtttcttc actagataat agaccgtatt gaatactaac
    29641 ccaccgattg ccaaatagat tcctagtact tgtcctaaaa gaagcaaacc caaacccacc
    29701 agcggaagca agccaagaaa aataaataaa cctacgcgtc caatcttttt actttttcca
    29761 tccgctagat attgttttgc aaaattatga tctttttttc ctaaacgagc gaattgatat
    29821 tggatttttt ctctcagttg aggattttcc tgataaaaag caatcagttt ttctaactgc
    29881 tgatcttcac caaaatcaaa gctgcgtaaa cgttgataca acgcttctga acctacacta
    29941 gaataggtac tgttgattcc ttcgaatact tcgaacatat ccaggtcata ccaagtaaga
    30001 tcatcgattt cgctatccca tgaacggaac ttcttctccg tgagccatgc ttccttcaag
    30061 ctttcttctt tatcaaatct cggttgataa ggaatttttt cccatttgct acgaactgtt
    30121 tcctttaatt tcaaacgtga aaaaatgtct aaagcaacta ataaaataac agctgcaata
    30181 ataattaaaa cgataaattc tctttgaccc atatccctct ccgttccttt atttgttagc
    30241 tttagtatag cactgttgcg ctatttgaaa agagggtaaa aaaacacctt tcaaaataaa
    30301 aggtgttttt ttcttgtata ttacatattt atctctcatt tatcaaaatt gacaaataat
    30361 catagggagg aattgttgtt aattcttgtt tattctccag tgcattgaca actgtcccaa
    30421 gggaaaggat agcctcaggt actatttttt cttgttctgt tggattagct aagcgaagaa
    30481 caaatccttg ttcatgaaaa taagaaggat aaatcgatga tacaattaag tcttcaggta
    30541 attcaatcaa tgaaaattta cgaggaacat caagttcatt ttgtaatggc caaatcttgt
    30601 tatctaacct gtgaataaat acattcagtt tctgcttttg ataagaaata gattgttcta
    30661 accgtttttc tgcctgtttt gccactttga actcattaaa tcttccttct tctacattaa
    30721 atccaaaagt gactttatac tcacctatct cttgagctag cggtgtttcc atcatgacat
    30781 gcccttcatt tgtcgtatct cctgaagctc gcccaggtcg ccaagcaaga ttaggttttc
    30841 caagttcccc tgttgttgaa aataaggtta tgattaattg attttctata cgttcatact
    30901 cttttaaacc atctgcataa aacgtaaaat aatgatcatt ttctgccaca gagacactct
    30961 tatcgaatat ttctaaatta acaggtttct ctaccatagt ttctgaccaa ttcggaggaa
    31021 tgacatcagg ggtattttca ataaatccgt tttgaatttg tgcaattgat ttttcagatt
    31081 tatctaaaac attaattgct aagcgcatac gatgcgagta aacagtatta tgaattttga
    31141 gtgtgccttc aacgatttga ctttctccca gactgaacga tatttcataa gatatttctt
    31201 ccatttcggg tttttcagat aaacgatctt ttaaatcttt aggaagttga gcttttccgt
    31261 aaacaactaa tgtttcttgt aaagaatctt tatatacttt agctgtttct aattttagag
    31321 atagttctgt atctccttct aatggtgaat aatcatacgt atcgccatca tttgctgaat
    31381 cgatcaaatg aacgaaatca agatattgtc tatctccaac tatcaaattc aattgcccat
    31441 ctttaaaaga aagtttatat ttattgttac ttatctcagt tttgtctatc tcgattgctg
    31501 tttctaattt ttcattattt ttctcaaatt caacaacagt gtatcctagt gctggcacat
    31561 ttacatttat ttttatgtca agttcataat aagctggttc atcaaaatat tcgaaacctg
    31621 tagcaatcat ccgataagca tttttccgtt ctggaaaata aacttctttt tcaatgatat
    31681 tatagggact acctttgaag tgtattttct ttgaatcagc tactacatgc acgattttcg
    31741 atccactata attctcagtc gttgtgttga aaacaaggac ttcattcgat tttagcttta
    31801 atgcatcagc catccgtttt acaataaggt tttcgattcc gtcagctatc tcattagctt
    31861 ctttgattcg atggaaaata tcttccgcaa cattatctga aacacagcca ccaatactat
    31921 catgagcctg gttttgcaaa atctttttcc ataaccgacg aagtaggcct ttactgatat
    31981 ggataccatt tctttctgca atcagcatga gcggctcaac tcgttttaga attttttgtt
    32041 ccaatttaaa attttctatt ttcatttttg ttcttactga gccaatagaa cgatgaacac
    32101 gagagtaaac cggctgacga agttcacctt tatattcagg taattctttt ttgtttctga
    32161 taacttctac ataagaagga taatctgaaa taatattgtg gaatttactg tatttattca
    32221 acttctctac gacttgatca aaatttaaaa tcattgactt ttgatctaca cccgaaggta
    32281 ctaaaatatc tttgtttttt ccttgcatat gaagcatttc aactgcttca tccaactttt
    32341 cttttgcaaa ttcaggaata tctttaattg cgtctaaggt catcattcca gtcatataac
    32401 caaatggaaa attcatggca taaacaaatt tatctcccaa tcctttccag ataaaataag
    32461 gagatggaac catcgtttca aagtttaatc ctcgccaaca catgaaatta tcgatttcta
    32521 cttgatgcaa aagtgtaggc aaattcgcat tgaacccaaa cgtgtcaggc aaatacccta
    32581 ccatcattgg atctccatat ttaaggatcg tatcactgat tccaatcatt aagtttctta
    32641 aaattgattc agcatccact aataaggcat ctgtttgtgc ataccacggt cccacgaata
    32701 gttgtcctgt tttcatcagt cgttggataa ccttaagctt ttgcggattg atctccaaat
    32761 actcatcgac gattgaagtt tgtccatcta aacaaaagtt tactttaggg ttcctttcca
    32821 attcatctag aacttcagta aagacctgat cagacaatac gatggcatct tcatttgtaa
    32881 aataccattc tctgtcccag tgcgtgtgtt gaattatatg tgcatttacc atatcagatt
    32941 ctcctacttt ccttcttcta ctgaatttac ttgttgttct tttttatact tgatggattt
    33001 tagtgcattg accattaacg ctgtaaccac tcccccaata acaattgata ctaaatataa
    33061 aggtatattc gtaacaaaag gaattgccat aaaggttgaa agcattgttt cttgagtaac
    33121 accaaaaaat ccatttagac cacatgctac tgcagtgccc accacgatgc ttggtattac
    33181 tcgtaaagga tctttcacgg caaacgggat cgtcccttca gtaatcccca caaggcccat
    33241 aatcatagct gtctttgcat tatctcgttc cgattcatca taaagttttt tgtttaaaat
    33301 tgttgctaaa aacattccaa atggcggaat agcaattcct aataacatgg ctgtactagg
    33361 tccaaagctt ccgcttgaaa aagaagcaac cccaaaagca tatgcgattt tattgatagg
    33421 tcctcccata tcaaacgcca tcattcctcc taaaatagcc gacatcaaag cagcatttgc
    33481 tcctgacatg ccttctagcc aattagtcag tcctgttgtc attgcttgaa taggcgtagc
    33541 tagtacatac cataatatga ttccaacaac taatgtagta acaaaaggaa tcagcataat
    33601 tgattttaga ctaataactt gcatcggtac ttttactttt ttcaatgcat tagctaaata
    33661 gccacaagct aatccagcaa ccattcctcc aataaatccc ataccaagat tttgacacat
    33721 catcccagtg ataaaagctg gtgctagacc gggacggtca gcaattgaat atgcgatata
    33781 ggctgaaatc atcggtacga taaactgtaa tcccgtctga ccaatcattc gcaggactcc
    33841 ccagaatgta tccgtctggt cccaaacacc tgtgccacca aaaatgactg caatagaagt
    33901 tagtaaccct gctgctacga caagcgggat catataggaa accccacttt ggaaatgatt
    33961 tagaatttct cttccttgtt tcttgaattc cattagtaac tcccccacga tatatttttt
    34021 atttgttaat taatgcaatt gcttcatcaa tcgtctcttc accatctttt actacctctg
    34081 aggtccctac tgttaaaatc ggtttaccgt caaagcgacc tcgttctgaa acatttgtat
    34141 ctactgcaaa tatgacaaca tctgcctcgg aaacatccga aattgaaagt ttgttttcta
    34201 tccccatagc cccctgtgtt tctactttaa tatctaaccc tttcttcttc gcaaactttt
    34261 ctaaattagc ttttgccata taagtatggg caatccctgc gatacatgct gttactgcta
    34321 ctatttttgt catatgaaat tcctcctttt aaaatgatag agcttttacc aattcttttt
    34381 tatttctcga atcttttatt cttttaacaa actcgtcatc catcaatctt ccagataatt
    34441 ctgctaaaat acgtaaatga ttagtacctt tatcagtgtc ttttattgct aacaaaaaga
    34501 cgagatcaac tggttgatca tctaatgcgc cccattcaac agaccgcttt aacttggcta
    34561 cagccactgt tgattcaatt actgctaggc ttttgccatg aggaatggcg atatttttcc
    34621 caattcctgt ggtcatatgg ttttctctgt caaatacgtc tttttgaaat tgtttgtggt
    34681 cagacacaaa cccattagtc tctaacaatt tcgataattt ttcgactaca ctttttttat
    34741 cagatgcatt taaatctatc actatattat ttatattgat tttttcactg atcatttata
    34801 agccttcttt caatatataa actaattttt caaacgacga actcgttttt aaatttgcta
    34861 ataactcatg attcgaagcg atttcattga atgtttcata aattttattc aattcaggtt
    34921 ttactttttc attaagtgca aaaaagaaaa cagaatgaac aagtgtccca tcccaatcaa
    34981 ttccttctgg attaacgtag acacagatta ctggcttttt tataaaatct acttcgatat
    35041 gcggcatagc aaaatcattc atcgctgttg aagatagttt ttctcttttg attgctccct
    35101 ctagtatccc ttctttcgcg taattttctt ttaccaattt tttggtaatt atatttaaaa
    35161 cgttcacttg attatccttt atttggtggg taaaaaagca aaatcgttta tctaataaat
    35221 ttagaaaagc atcttctgtt tgttcattta actgtagata ctgttttact tttctgacat
    35281 ctgcccctaa catcaaagga ctaacaacaa taacaggaaa atttgtattt tcaatcggaa
    35341 tcgtgcttat aacaagttca tcagtgactt ttctatcttg tagttcattg atgcttagta
    35401 catcttctat ctcaaccata tctgcaaaac cgttatttat tctttgctct aataattttg
    35461 atgttccata tccgctacta caaactaata tcactttcgt tttgtcaggt ttgtaacgat
    35521 ccaaaagtga ttgaatatgg agtgttacgt aagcgatttc atcttcatta aaatgtatac
    35581 agaatctctc ttcgatttcc tctaataaat ctacacttat cataaatgac cttttaaaag
    35641 aatatttgat tttgtccgta taagggttat agatatttac tcccaatttg agtcttttaa
    35701 ctgctgcatt gagatgtaat actagattat tgatcaattc ttcatcagga taaaattcat
    35761 ttaatttaat tcttactaac tcttgtagct caacacccat atctaaatag gaaagcttcg
    35821 tttgatctaa gtcgtgattc atagcatttt tttcaatcga agtaatgtga atgtcaacat
    35881 aagcttgttc atctattggc acaataattg aaaatgcttt ttcaatcatt ttgattaaaa
    35941 taagtgtatt ctttgagatt tcttcttcag aattattact acgtgataag aaattgcttg
    36001 tttcaatcct ttctatcgca atagcaaggt ggatagctaa agtttgaaat tcataatctg
    36061 taaatttcaa ttgtgtctta ttcatgtatc gattaagcaa ttcggctact tttttcaata
    36121 tgtccttatt taagaaatta ttcgcttcac caatgaaatt gatattcaag tctaagagat
    36181 ctgttttact gttagatgct gtaaagccac cccaataata gttcacaact tctgacatca
    36241 accttctttt acttttttca tcagctttga tgcgcacgcc atttcgatct gaaactaagg
    36301 acatcccatg cttgtttagt ctttttctaa catctttcat tgtgctttct accgtcgacc
    36361 tgctcacgta taattcgtca gcaagatttt gaatctttag agaatcatta gtattcaata
    36421 atttagcaaa cacataagtt agacggtcct ccggagagtc tgcgatattg attttatgac
    36481 tggataataa atttcgaagt gtttcttttt ttccaataag cgaaacgcct tttttaggtt
    36541 gaaccaacat ttgtacatct ggcatttttt ggattatttc tttcaaaatt aaaatatctt
    36601 tgctaattgt tttcgtagat acatataatt gttctgataa ttctttgtaa gttgtgtgct
    36661 cattttcaat caaaaagtat agtattttca tttgccgttc gctaaattcg atgcccatta
    36721 tcttcacctc ctgaatacag cttaagtgta caattattat ctctattttc atacagaaga
    36781 aagttcttga ttaatgtaga agtttctaat attcttgatt atttcaaatc aataaaaaag
    36841 cctgcaatat ttatatcaca ggcttttttc tctattaaat atatataaga taatacattt
    36901 ttctactagt tctcactaat cttgtataat taaaccctcc gcaacttgac ggagatggag
    36961 aagatgcccc cgtctaatct agcggtcatc tctcctccca ttccttccac caattttttt
    37021 gacaggtaaa gcccgattcc gctagattcc gtatttgtgc ggctggtatt ttcggtataa
    37081 aaacgctgga agactttttc aacagaggtt tgcgttcctg gtttgatagg attggccact
    37141 gttaatcgaa tgaatggatc ctcttttgaa aatgtcacct ttgcttgtcc atctgcataa
    37201 cgcaataaat tctgtatgat attttgcagc actcgcagca acatgagcgg atctgctaat
    37261 acagttgtat ttatcgagtg ttcagcgaac gctacctcga tatttttctc agaaaattgt
    37321 tcataaaaag agaaaaatac ttcttccacc tctttagaaa aagaaagcgt atggagatcc
    37381 atttcttttt gcttcgtctc tattcgagca agatcataaa actgatccgt catactgagt
    37441 aatcttgcaa cagattgttt gatgatcgtt aaatacttct cccgtttctc cgtatcctct
    37501 acctgttcca gtaattgtac ataaccgtta atagcagtca aaggagttct gagatcatga
    37561 gaaaggccga cgatcgatag tctgatgttt tcttccattt cttgaaatgc ttgtcctttt
    37621 tgttcatttt catccaacca tgtattcagt gcatctacta ggtccattag attcttttct
    37681 cgaaattcga ctgaaagacg accaccatat tcttgtcgtt cagaaagagt ggcgattttc
    37741 ttagttaatc tcttgatttc cctttgcagg aagaaaataa aacttcccat aaagataaca
    37801 acgagaagca acagccattt aatcaaatct aaaccccact ccccacaccg tatgaatata
    37861 cacagcatgt gcctttgcta gcttccctcg aagattggaa atatgcatat tcactgtttt
    37921 ctcactatca aaatatggtt cttgccaaac tgtttcataa agatttgctc gcgaaaatac
    37981 ttttttcgga tgttctaaaa aaagcttcag cagatcgaat tctcttcctg tcaaatggac
    38041 agccacacca ttcacattta catccctcga ctctttgtcc agtaagattt ccttgtaata
    38101 gatgcgttgc gacagatctt ttacttggac agaagtctga tgacgaagtt ggatgccgat
    38161 tcgtaacaaa agttcttcga tatcaaatgg tttcgtcaca tagtcatccg ctcctgctgc
    38221 caacaaggaa actttatctc tttgatcgct ttttgctgaa agaacgatga tcggaacatt
    38281 cgatgtctgt cggatttctg ctaacaatgc ttcacctgaa agccctggaa gcatgagatc
    38341 tagaaggatc aaatcgacag gatatgtgct taacaataat tttccttccg tacctgaata
    38401 agcatcaaga agtttgtatc tctgttcaag aacctcctcc agtaaggaat gaacagcttc
    38461 atcgtcttcg ataatcaaaa tagtttccag caggaccacc tacttaatgt cagatttttg
    38521 gaaaataaac attcctagag ctgatgatac cacgattgtt actagactga ccagaatcat
    38581 tttcggtgct tgcgaataag ttgcttgttg cgcaaagtcc gtatacatga gccacgtttc
    38641 cgtaaaccac tccgttagaa attccaagcc tttgattttt gcgaaaacac cgggaatgaa
    38701 ggccgttccc atgatataaa gaaaagaaag aagcaaactg acactggtac ttctagtgat
    38761 gaatgtcaaa gccactggaa cagataatgt ccctaatgtc agcagaagca atacaggaaa
    38821 tacttttaga acataatttc catagttttt gattccctca acttcaccaa atccgaaagc
    38881 aagtgtgtaa gcaagcatgg ctagtcccgt gatcaaaacc acgccaagtg ttgtgatcaa
    38941 aagcgtaacg agaagtttcg acacataata agtcattcga ttccgtccta aagataacgt
    39001 attgcgaatc gtaccgtttt gaaattcttc cccaatataa aagcacgcaa atgctgcgaa
    39061 agccagaaga atccatgcag ccattttttc taccattaaa atccctgttg caccgttgat
    39121 gactgtatcc gttgcttggt ttaattcatt gccgtatttt gtatgcatat accattcgtt
    39181 ccaagaataa aaaagcggaa gtacgaccat cagtcctagt gagacccaca ttttacggct
    39241 cttccatact tttatttttt cagcagttaa tagattaaac atgtggattg cctccagtta
    39301 attgtaagaa ataatcttcc agtttttgcc caactaggtg aataccatcc acaggaactt
    39361 ttgcttctac caatgcttga ttgatggctg ctacttggtc aattccttca aaaagctgga
    39421 taacacggct agattgtaca aaataatccc tataaccaag agagtcgaga accgttactg
    39481 cttgttccgt cgccgaagtg tcaattttta taaattgacg agattcttgt gccaattctt
    39541 ctttcgataa ttctttgatc aagtgtcctt catgcaaaat accatagtga gtggcgatct
    39601 gtgacaattc atctagcaag tggctagaaa gcaagacggt gatgccccgt tcttttacca
    39661 aacgttggat gatttctcgc atttctgcca tccctgctgg atccatccca ttcgtcggtt
    39721 catccaaaat caaaaattct ggattcgtga tcagtgcatt tgcaatagct aaacgctggc
    39781 gcatacctaa agagaaattc tttgctttct ttttccctgt attttccaat cgcatcattt
    39841 tcagcaggtc ttcgatttct ctatccgaca caccgccgtt cgctgcttgg atacgtaggt
    39901 tatctcttgc agttaattct ggataaagag caggggtttc aatcgattga cccatacgtc
    39961 gtcttgctgc ctgcaaatcc gtcgttccaa ataattcgat cgaaccttca tcaatcgaga
    40021 tcaaacccat aatagttctc ataaaggtag acttacccgc tccattttcc ccaatcaatc
    40081 catagatcat tccacgtttg atttcgattg atactttatc taatgctttg gcagcaccgt
    40141 attttttggt tataccagtt gctttcaaga ccgtttcatt tccaaaatcc atacttatcc
    40201 ttctttctta ttgatgagtg aagtatagtt gacgggtata aagaaagcag ccagaaatgt
    40261 ataaagaaag tgtaaatttt ccaattgaat gtcaaaaaaa acaatcggac aatacgtgtc
    40321 tttcctatta tcaggcagtt tgttatacgc ttgtatcagt ttcctgattc tttcttttcg
    40381 accaaagtcg tttctctgta ttcctcttca ctgaaaattt ttgcttcttt cagatcaagc
    40441 ttgagtaatt ttaccagacc ggttataagg ataactatag caagactccc tcccagaaaa
    40501 attagactgt ctcgcagacg tggttgcgtt gtcttccaat caaagagcgc accaaacagt
    40561 gctaatccaa gtggactggc caccatggta atcgttgtta tcgttgacat aagtcgtcct
    40621 tgtatatgcg ttggaacttc tcgctgaagc cagaccatat aaaaagcaaa agaaaacatt
    40681 aatccttaaa aacggactta tgaaaaataa tacatgccgt ttgggattta caattagcta
    40741 ccaaataaga ggttatgaca aaagactttt cacaatccct tcttccgaat aaacggtgtt
    40801 ctcctgccaa ctcctcggtc acaagtcaca atatttatca aacatgagaa gcaatttttg
    40861 taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaga agcggataaa
    40921 taatattgtt tgatgatact ttatcttttt cccgtttgtt tatagatcga atgatattat
    40981 agaccaagaa tcctacctat taacatagct aaaaacacaa aaaaggcact ttccaaattg
    41041 tggaaagtgc cagaaaagtt aggattaagg taactgcgct cagcattgct tcgcccagta
    41101 cgattctcgt aactcgtgaa ctcgaacgat aatcgcaatt aacgttttga gaactgtgaa
    41161 gctttacggg ctttcttaag acctggtttt ttcttcgtat cattgaataa gtttgaaaaa
    41221 ccttgattta taaaggtttt cccgtaaata tattttatta tatttgatta aatttgaaat
    41281 gtttgtgttc taaaatgtgt tctaatttaa aggcagtata tttcgtattt tagattaaat
    41341 ttttaggctc attcattctc aaatccattc tattcagtca ataaaaattt taaaaagact
    41401 ttataaacaa agatgttcaa gcgagcatct tatttttttg tgcttaattt gaaaggagaa
    41461 catttcatgt ataaaaaaca aaaaaagaaa ttatgtgtat taactatttt gagtttggct
    41521 gttcaagcaa ttgttggagc aattgctcct acgattactt ttgctgatga aattacccat
    41581 ccacaaacgg taaccgtaga actagattta gcacatcaat atgctgttga aggaactttt
    41641 agtgatggtc gtccaatgtc agaagtcact gttccgcatt atgcagtgta caacggcttt
    41701 aaacaagata ttttctgtat tgaaccagga gtcccgattt acaatgagtt cactcctggc
    41761 tatgagaaaa acccgttacc agatatgtcc gataaagcca aattagtttc cgttttatgg
    41821 aaaaaagtag gtacagatgc agatactcat attgtggcac agaagatgat ctggcaagaa
    41881 gttaatgggt atacccttca ctcaataaaa cgatcagatg gtagtgccgt aaatatcgca
    41941 gccattgagg caaaaataaa tcaagccatt gacgattatc agaagaaacc aaccttccat
    42001 aatagtacgg ctaaaacagt attagggcaa tcgactactg tgacggatac gaataatctg
    42061 aatttgtcag agttcgatga ggttgtggaa aatgccgcaa acattgatta tcgtgtgaat
    42121 ggtaatcagt tgataatcac cccaaatgcc aattcaaaag aaagtggtgt gctgacgctt
    42181 aagaaatctg ctggtaccgg aacacctgtc gcctataaaa aggctggcca acagacttta
    42241 atggccgggg cgattgataa acctaatacc tacacaatca aaattgatgt ggaaacggag
    42301 ggttctttaa agatcaaaaa agtcgataaa gaatcgggtg atgttgtacc aggaacggtt
    42361 ttccatttag actttggaaa aactttacct gcaaaagacg tgactactga caaagaaggc
    42421 attgctacat tggatgagat tcctcatggt acaaaagtaa ccattaccga aaaatcagta
    42481 ccggcgcctt atacgattga taccaccccc atgactacca ccattaaagc aggcgaaacc
    42541 atttacgtga cttcaaaaaa cgcacgggaa aaagggcaaa tcattctgga taaaagcgga
    42601 gttgaaacag ggagtgatct ttggaatgac aattattcct tagctggtaa tacgtttgcc
    42661 attcgcaaag acagtccaac cggtgaaatc gttcaagaaa tgaccacgga tgaaaacggt
    42721 catgcggaaa caccaaaaga gattgctaat gcgttggaat tgggaaccta ttatgtgacc
    42781 gaaactaaag ctagtcatgg gttcgtgaat acgttcaaac ctgtaaaagt cgaattgaag
    42841 tatgccaatc aaaccgtagc ccctgttacc agtaacgtaa aagggcaaaa tcaagaagtc
    42901 actggcgaaa ccactttgac gaaagaagac aaagatactg gggataaagc acaaggtaag
    42961 gcagtctttg agggtgctga atacaccttg tttactgcta aggatggaaa agctgttaaa
    43021 tggagtgagg cttttaaacc agagttagcg aagggaacga aaggttctga tgaaacggtc
    43081 actttgactt tagacgaaaa gaaccaagtt gccgttaaac atttagctat caacgagtat
    43141 tattgccaag aaacaaaagc gcccgaagga tatagccttg atgaaacaaa gtatcctgta
    43201 tccatcaaaa aggtggatga tagcgaaaaa aatgccgtga ttacccgaaa tgttacggca
    43261 aaagaacaag tgattcgctt tggctttgat ttctttaaat ttgctggatc agctgcgggc
    43321 actaccgaaa ctggcttcaa tgatctgacc tttaaagtgt cgccattgga agggaccaat
    43381 gaaatcacag gtgccgaaga tgaagcgacc acagcttata acgagcaatt agggtttgat
    43441 ggttatggca agtttgaaaa tcttccttat ggggattatt tacttgaaga agtagaagcc
    43501 ccagaaggtt ttcaaaagat tacgccatta gaaatccgtt ctacttttaa ggaaaacaaa
    43561 gaagactttg tgaagagtga gtatgtcttt accattaccg aacaagacca aaaacaacca
    43621 attaaaacgg tgaccgttcc ttacgagaag ctgacgaaca aagcattttc tgttagtttg
    43681 aaccgtttaa tgctctatga tttgcctgag gaagaagata gtttaacttc tcttgcgact
    43741 tggaaagacg gaaacaaaga attaacttct ctggattcta ccgagctagt tgataaattg
    43801 agttacaatc tacatgaaat caaagaagac tggtatgtgg tagcgcaagc cattgatgtg
    43861 gatgcgacaa aagctgccca agaaaaagat gaaaaagcca aaccagtggt gattgcagaa
    43921 acaagcgcaa cgttggcgaa caaagagaaa acaggaactt ggaaaattca gcataaatta
    43981 accgccgaac aagttttaaa taaaactatt gtcttattca actatgtgta tgaaaataag
    44041 gaagcttttg aagcaggcga taagccagta gcgaaggatg ttagcttgaa taaccaagcc
    44101 caaactgtca gttgtacagt ggaacaccat gtttctatcc aaacaaaggc ccacctagaa
    44161 aacggttctc agacctttac tcatggtgat gtggtggata tgtttgatga tgtgtcgatt
    44221 actcatgatg tactggatgg ctcaaaagaa gctttcgaaa caattctgta tgctttatta
    44281 ccggatggta caaacaaaga aatttggaaa tctggcaaga ttgattatga agtaaatgat
    44341 aaagaattca ccaaaactgt gcttgcgaaa aaagtagata ccggaaaata tccagaagga
    44401 accaagttta cttttgcgga aatcaattac gataaagatg ggaatatcaa tggaaaacac
    44461 aatgaagatt tgaaagaaaa atctcaaacc ttaacaccaa aagaagttcc aaccatacta
    44521 agtacgccga aacaaccgga aacaccaact gttccaagtg gctctcaaga atctagtccc
    44581 acagtgaaga ccttccctca aaccggggag aaaaattcca atgttttact gttcattggt
    44641 tttactttga tttttgcgac ggcgggctat tatttctgga atcgccggaa ctaaggtgat
    44701 gagatgatac aagtaaatcc taagaaccaa cgtgcgcgac cgcctcctaa aaaagtagtc
    44761 gcgctatttt tgtatccaaa actaacaatg aaaagaggaa aagaagatgg aattgaaatt
    44821 tgtcgtgcca gatatggctg aaacctttgg aaagttaagt tatgccggtg aaggagaaat
    44881 tataacagaa ggatatggac ggaatactac ggtgattggt cgcagttatc atttgtattc
    44941 cagtaagcaa cgggccgatg atattgaggt ggtagtagct gcggaagccg gtgaaaagga
    45001 ttttgatcaa gaccaaccgc taaaagccgt gaatccccat ttggttgcca aaggctatga
    45061 gattgagaat cgtgggttta ctgattacgt gttgtatgtt gatgatttag tgaaagcata
    45121 ggaggaaaag aagatgagat taacagaagg tattgtcgta gattcaggtt taacatttgg
    45181 gaagttgcgt ttttccgcat tacgccgaga agtacggaag caaaatgagg atggaacaat
    45241 tggtaatgag gtaaaagaac gaacctataa tttaaaatcc tctgcacaag ggcgaatgat
    45301 tcaagttagt atcccagcta atgtaccctt acgcgagttt gcttatgatg cagaggtaga
    45361 gttggtcaat ccaatcgtgg ataccgttgc caattatgtt tttcgagaag gaactaccgt
    45421 taattggttc attaaggcgg atgatttagt cttgaagcgg cagccgaatc aaggaaatcc
    45481 tacgaaccaa aatgaaagaa agaaataggt gaagattatg gaaattaatg ttgaacatat
    45541 tttagattgt ctcgatcaat atggaaaagg cgagctgact gaggaacaac tcgttaaagc
    45601 attaacctct gatgaaaaaa tgtttctgat tatacatcaa ggtttacttg gagaaaatag
    45661 cgacagtgaa gaagactctg atgtactaga ctggttagga gaagaagagt ctttctttat
    45721 agttgtcgaa gtaaatgaaa acttatgtcg gcaggcagaa tccattttgg aagaaattgg
    45781 tgtggagatg ccggatgcta ttgaaggctt tttaaatcaa ttggttgaaa cgaaacaact
    45841 cccctcctcg tagcagtaaa tgactagcat aactttttga aattgcctaa tgaaatccta
    45901 ttgggctttt tcgattggag gtggaaacca tcaaaatgta caaaggacat cgcatacgcg
    45961 caggagatca gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg
    46021 gttggatgag cgtcttttat tttcaagagt ttagacaatt tgatatttct aagctatcac
    46081 tttctactat tgaaatcgtt tggtctataa aagatttagt atgtctgctt ggaagtctcg
    46141 ctttttcagg agctatgata ttgctttata ttcacttttt tcttgatcat tggcgaagct
    46201 tgtggcatcg acaaaagcta gctcggatga ttctagagaa ccattggtat gaagtgaaac
    46261 aaactcaaag tgaaggcttt ttcaaagatt tgaatagtag ccgaaccaga gagactatca
    46321 gttacttccc caaaatctgt tatcgaatga aagatggatt actgtctatt cgcgttcaaa
    46381 tttcacttgg gaaataccaa gatcagcttt taaaattgga aaagaagtta gaaagcggac
    46441 tgtattgtga gttagtagaa aaggaactca aagactccta tgtggagtat actttactgt
    46501 atgatatgat cgccaatcga attgggatag acgaagtagt ggcagaaaat gggactctgc
    46561 gattgatgaa aaatcaagta tgggcttatg attctttacc ccatatgtta atcgctggtg
    46621 gcacgggtgg agggaagacc tatttcctcc tcaccattat cgaagcacta ttgaagtcag
    46681 atgcagaatt gtttatcctc gatcccaaaa atgcagattt agctgattta ggtacggtga
    46741 tgcctcatgt ttattcacaa aaggaagaaa tttctgcttg tgtggaagat ttctatgaac
    46801 gtatgatggc tcgtagcaag gcaatgaaag aaatgtctaa ctacaaaaca ggagagaatt
    46861 atgcctatct tggacttcca cccaactttt taatctttga tgaatacgtg gcttatatgg
    46921 agatgttaac gacgaaagaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt
    46981 tgggtcgtca atctggtttc tttctgattt tggcttgcca aaggccggat gcgaaatatt
    47041 taggagacgg aatccgcgat caattcaact ttcgcgtggc tttgggtcgt atgagtgaac
    47101 tcggatattc catgatgttt ggggaggtcg aaaaaaactt ctttatgaag cacatcaaag
    47161 gtcgaggtta tgtggataca ggtggcagtg tgattagtga gttttatacg ccacttgtac
    47221 caaaagggta tgatttctta gattcaatta gtaaattaga aaagatgaat gattgagtga
    47281 tcttcaatac tgactttata cttcaagtaa cgtataatac ttttatatag taggaagaaa
    47341 ggggataatt aatatggaaa gtaatgattc ttatttagag tatgcaaaag caaataagga
    47401 taagtttatt tcttatatta tcaaagggaa atcccccgaa gttggacgag acgcagtttt
    47461 tatggcaggg agtcctgggg ctggaaaatc agaggttgcc attggattag ctgagaatta
    47521 tgataaccat gtgattattg atgcggatta ctttcgcacc cagtttcctg attataatgg
    47581 aaaaaactct agtctctttc aaaaagcatc ttcttggttg gtagagcagg catttagata
    47641 tgtcttagat catggctatt cttttattct ggatgcaact tttgcaatat taagtgctga
    47701 aaaaaatatc tcgcgggcgt tgaaaaaaca ttttcgagtg acgattttct atgtttatca
    47761 agaccctaaa atcgcttgga aatttacaca agaacgtgaa attgcagagg gacgtcatgt
    47821 gccgaaaaag gcatttatta acgctttttt caaatcaaga gagaacattg caaaagtaaa
    47881 gagtaaacat ccagatgtat tgcttcatat cataataaaa gattatacga ataatatttc
    47941 cgaagttcat tatgctacgg ataatctaga attattttta ccactagggt atagtaggaa
    48001 agatttggag gttcaattac atgactgaga aagaacaagt aacgaaaatt gtaaagaaat
    48061 acaataagag cattgcggat ttatcggaaa atgctactgc aaaagagttc aaaacggtga
    48121 ttaaatatgt agccgatcag gccaatgaaa aacaacggaa attagttgga ttaaataaaa
    48181 aatagtagga caaattaata atgtatgagc caagagcaaa atgttcttgg cttttttctt
    48241 tgcaatgaat gaggtaatgt atgagatttt tagatttatt cgccggtatt ggtggctttc
    48301 gtttaggtat ggaacaggcg agccatcatt gtatcggttt ttgtgaaatt gataaatttg
    48361 ctagacgtag ttataaagca attcatgata caagtaagga ggtggaaatg catgacatca
    48421 caagtgtatc agatgagttt attcaatccc tcggaccagt ggacatcctt tgcggcggat
    48481 ttccgtgcca agctttttca attgcgggaa agcggcaaag attttccgat actcgaggta
    48541 ctttattctt tgaaatcgct cggttcacca ctcttctccg acctaagctt ttattccttg
    48601 agaacgtccg aggattgctc aatcacgaag gaggggctac gttcgagacg atcctccgaa
    48661 cgctggatgg attggggtat gacgtggagt ggtaggtgct taactcaaag gcctacattc
    48721 cccaaagccg ggagcggata ttccttatcg gacattctcg agacgcatgt accgaacaag
    48781 tatttcctat cattggaccg tcttcaacat ctgatcaaaa catcagaaat ttggtaaata
    48841 tcaatccttc caatcgagga atgggtggac aagtctatgg ttcagatggc gtagcgccaa
    48901 ccttaacagg tgatgaagga atcaaaatcg cactgccagc aagggatgga atctctgtag
    48961 caggactatt accgggaaag tttgaacaag gtaatcgagt ttatgaagtt actggaaccg
    49021 cccccacctt gtcaacgaaa caaggtggta caaaaatcat gattcgaaaa aatgaaacag
    49081 aatatcaaga ggtgaagcca gaagacagtg tgaatctggc ttttcctaat tccacaagtc
    49141 gccgaggtcg tctgggaaaa cagagtgttc ataccttact aacaggagac caacaagcga
    49201 tcgtcacgga tcagtatcaa attcggaagc taacacctag agagtgttgg cgacttcagg
    49261 gctttcccga ttgggctttt gatcgagatt ctcaagtcaa ttcagatagt cagttgtata
    49321 agcaagccgg aaactctgta acagttccgg tcatttttga tattgccaga agattaaaag
    49381 agttggatgt acatggttta tgatgagttg attggagaaa tttattgggt gattggaaag
    49441 attcagtcag acccagaatt agaagaacaa ttgcgacggt taaaatttga tattcgcaag
    49501 aatggtgtca aagtcgctgg cgatccatat ttaatgaatg aggagacgga tgctcgaatt
    49561 gaaataaatc aagtaattgc agaatttgag cggattgcgg accaagcaaa agaaccagat
    49621 attcgtcaat acttgttaga aatgaaagca gagttggaag taaatggtat tacagatgag
    49681 taacctaaac caacacaact gactgttagg cgctgaccgc ggaggattcg cgaagcagaa
    49741 atcctccgtg gtgctgtgcc tgttcatgga cggcgttagc cgaccatgat gtctcacccc
    49801 cgtatctaac aggggggtac aaaaacacaa aaaataagta agcaaccatt aagaatgctt
    49861 gttgtatcaa agatagtaag taatttgtat aggtgttaac tcatttgaaa aagttaacac
    49921 cttgaatttg gaggtgagaa cttggcacaa cggaatttag attatcggct attaaaagac
    49981 cgacgcaacg aatacggcgt ttcacaaaat aaattggcta cggcttgtgg acttagtcgg
    50041 ccgtacttaa atcagataga aaatggtggc gtaaccgcat ctataaaaac catgaggaaa
    50101 atttttgacc aactggaaag ctttaatccc gatttgcctt tgacgttact gtttgactat
    50161 gtaaggattc gctttcccac aacggatgca cgaaaaatta ttcaagaaat tctccatttg
    50221 aaatttgagt atatgctcca tgaagattat gccttttact cctatcaaga acagtatgtc
    50281 atgggtgata ttgtggtgat gttgtctcat gaagaagata aaggtgtgct tttagaatta
    50341 aaggggcgag gttgccgaca atttgaaact tttttactcg ctcaaaagcg tagctggtac
    50401 gactttttcg aggattgtct aaaggccggt ggcgtgatga aacgcttgga cttggcaatc
    50461 aatgatcgag tggggctatt ggatatacct gagctaacga aaaaatgtca gaaggaagaa
    50521 tgtatctcct tgtttcgtac ctttaaaagt tatcgttccg gggaactttt aaaggctgat
    50581 gaaaaggacg gcatgggcaa taccttatat atcggcagtc tcaagagtga ggtttatttc
    50641 tgtttgtatg aaaaagacta tgaacaatat atcaagttag ggattccatt agaccaaact
    50701 gagacgaaaa atcgttttga gattcgactg aaaaatgacc gtgcttttca tgcgattcaa
    50761 gatttgttaa aaggtcgtag cattgagagc accacgtttt ccattatcaa tcgttacttg
    50821 cgatttgcgg ataaagtaga aggtaaaagg cgaaccaact ggcccttgaa tgaacaatgg
    50881 gggcgtttta ttggacggaa tcggaaagag attcaattaa cttccgagcc aaaaccgtat
    50941 accattgaac gaaccttgaa ttggctaggc cgacaagtcg cccctacgtg gaaaatggct
    51001 aaggagttgg atcgattgaa tcggacaacc tatatccagg atatggtaca gaatgcacgc
    51061 ttatcagacc gacataaaaa gattttggag caacaaagta tggcaattga aaatttgatt
    51121 atatgaaaag aggaatcgtc atgggaattg taaaagatat ttttttggta tttggtggca
    51181 gtatgcttgg tgttactgtg atgtgcttga tgaatgcaag tgcagcagcg gatcgagcaa
    51241 tggaaaagaa aggaaagtga caagatgaat ttcggacaaa attt
//
LOCUS       DACGLI010000015        49690 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.016, whole genome shotgun sequence.
ACCESSION   DACGLI010000015 DACGLI010000000
VERSION     DACGLI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.016"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            220..1278
                     /locus_tag="IXT22_000942"
     CDS             220..1278
                     /locus_tag="IXT22_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAQ4862324.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1297..2316
                     /locus_tag="IXT22_000943"
     CDS             1297..2316
                     /locus_tag="IXT22_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAQ4862325.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2418..3134)
                     /locus_tag="IXT22_000944"
     CDS             complement(2418..3134)
                     /locus_tag="IXT22_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4862326.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3103..3888)
                     /locus_tag="IXT22_000945"
     CDS             complement(3103..3888)
                     /locus_tag="IXT22_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4862327.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3879..4628)
                     /locus_tag="IXT22_000946"
     CDS             complement(3879..4628)
                     /locus_tag="IXT22_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAQ4862328.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4926..5450
                     /locus_tag="IXT22_000947"
     CDS             4926..5450
                     /locus_tag="IXT22_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862329.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5466..6965
                     /locus_tag="IXT22_000948"
     CDS             5466..6965
                     /locus_tag="IXT22_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAQ4862330.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7053..7655)
                     /locus_tag="IXT22_000949"
     CDS             complement(7053..7655)
                     /locus_tag="IXT22_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4862331.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7759..8715
                     /locus_tag="IXT22_000950"
     CDS             7759..8715
                     /locus_tag="IXT22_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAQ4862332.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(9020..9976)
                     /locus_tag="IXT22_000951"
     CDS             complement(9020..9976)
                     /locus_tag="IXT22_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4862333.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10150..10710
                     /locus_tag="IXT22_000952"
     CDS             10150..10710
                     /locus_tag="IXT22_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862334.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10703..11527
                     /locus_tag="IXT22_000953"
     CDS             10703..11527
                     /locus_tag="IXT22_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAQ4862335.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11537..12154
                     /locus_tag="IXT22_000954"
     CDS             11537..12154
                     /locus_tag="IXT22_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAQ4862336.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12172..12855
                     /locus_tag="IXT22_000955"
     CDS             12172..12855
                     /locus_tag="IXT22_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4862337.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13538..14821
                     /locus_tag="IXT22_000956"
     CDS             13538..14821
                     /locus_tag="IXT22_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4862338.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLRTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVNKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14837..15724
                     /locus_tag="IXT22_000957"
     CDS             14837..15724
                     /locus_tag="IXT22_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862339.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15741..16577
                     /locus_tag="IXT22_000958"
     CDS             15741..16577
                     /locus_tag="IXT22_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4862340.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16580..17203
                     /locus_tag="IXT22_000959"
     CDS             16580..17203
                     /locus_tag="IXT22_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862341.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17200..18492
                     /locus_tag="IXT22_000960"
     CDS             17200..18492
                     /locus_tag="IXT22_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4862342.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18851..18948
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19064..19645
                     /locus_tag="IXT22_000961"
     CDS             19064..19645
                     /locus_tag="IXT22_000961"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAQ4862343.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19648..20955
                     /locus_tag="IXT22_000962"
     CDS             19648..20955
                     /locus_tag="IXT22_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAQ4862344.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMILISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21371..21859
                     /gene="purE"
                     /locus_tag="IXT22_000963"
     CDS             21371..21859
                     /gene="purE"
                     /locus_tag="IXT22_000963"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAQ4862345.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21843..22976
                     /gene="purK"
                     /locus_tag="IXT22_000964"
     CDS             21843..22976
                     /gene="purK"
                     /locus_tag="IXT22_000964"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAQ4862346.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22989..24284
                     /gene="purB"
                     /locus_tag="IXT22_000965"
     CDS             22989..24284
                     /gene="purB"
                     /locus_tag="IXT22_000965"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAQ4862347.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24464..24841)
                     /locus_tag="IXT22_000966"
     CDS             complement(24464..24841)
                     /locus_tag="IXT22_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862348.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            25097..25825
                     /locus_tag="IXT22_000967"
     CDS             25097..25825
                     /locus_tag="IXT22_000967"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAQ4862349.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25825..26079
                     /gene="purS"
                     /locus_tag="IXT22_000968"
     CDS             25825..26079
                     /gene="purS"
                     /locus_tag="IXT22_000968"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAQ4862350.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            26081..26752
                     /gene="purQ"
                     /locus_tag="IXT22_000969"
     CDS             26081..26752
                     /gene="purQ"
                     /locus_tag="IXT22_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAQ4862351.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26753..28975
                     /gene="purL"
                     /locus_tag="IXT22_000970"
     CDS             26753..28975
                     /gene="purL"
                     /locus_tag="IXT22_000970"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAQ4862352.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28960..30399
                     /locus_tag="IXT22_000971"
     CDS             28960..30399
                     /locus_tag="IXT22_000971"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAQ4862353.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30431..31474
                     /locus_tag="IXT22_000972"
     CDS             30431..31474
                     /locus_tag="IXT22_000972"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAQ4862354.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            31471..32049
                     /gene="purN"
                     /locus_tag="IXT22_000973"
     CDS             31471..32049
                     /gene="purN"
                     /locus_tag="IXT22_000973"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAQ4862355.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            32046..33581
                     /gene="purH"
                     /locus_tag="IXT22_000974"
     CDS             32046..33581
                     /gene="purH"
                     /locus_tag="IXT22_000974"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAQ4862356.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33597..34871
                     /gene="purD"
                     /locus_tag="IXT22_000975"
     CDS             33597..34871
                     /gene="purD"
                     /locus_tag="IXT22_000975"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAQ4862357.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34993..35907
                     /locus_tag="IXT22_000976"
     CDS             34993..35907
                     /locus_tag="IXT22_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAQ4862358.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(36040..37605)
                     /locus_tag="IXT22_000977"
     CDS             complement(36040..37605)
                     /locus_tag="IXT22_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4862359.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37598..39049)
                     /locus_tag="IXT22_000978"
     CDS             complement(37598..39049)
                     /locus_tag="IXT22_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4862360.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(39063..40079)
                     /locus_tag="IXT22_000979"
     CDS             complement(39063..40079)
                     /locus_tag="IXT22_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4862361.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40299..41387
                     /locus_tag="IXT22_000980"
     CDS             40299..41387
                     /locus_tag="IXT22_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4862362.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41441..42967
                     /locus_tag="IXT22_000981"
     CDS             41441..42967
                     /locus_tag="IXT22_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862363.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42969..44174
                     /locus_tag="IXT22_000982"
     CDS             42969..44174
                     /locus_tag="IXT22_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862364.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44431..45408
                     /gene="guaC"
                     /locus_tag="IXT22_000983"
     CDS             44431..45408
                     /gene="guaC"
                     /locus_tag="IXT22_000983"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAQ4862365.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45672..47096
                     /locus_tag="IXT22_000984"
     CDS             45672..47096
                     /locus_tag="IXT22_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4862366.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47557..48666
                     /gene="pdhA"
                     /locus_tag="IXT22_000985"
     CDS             47557..48666
                     /gene="pdhA"
                     /locus_tag="IXT22_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAQ4862367.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48669..49646
                     /locus_tag="IXT22_000986"
     CDS             48669..49646
                     /locus_tag="IXT22_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAQ4862368.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        15850 a         8549 c        10924 g        14367 t
ORIGIN      
        1 ataatttaag ttaaccttaa aactaaactt cttaagtttg gttttaaggt tttttttgtg
       61 ttctagtaaa aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat
      121 aagtaacaat gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt
      181 ttttattgtg aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt
      241 cgatcgactt tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata
      301 ttattagggt ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta
      361 tcgaaagtcg tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat
      421 atcaatacag aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat
      481 attattctta ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca
      541 acgttgcgtg tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt
      601 gcgatttatg gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc
      661 tttttgtatt cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc
      721 aaagcgatgt tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg
      781 ttccaagggt atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta
      841 gcgtttttgc gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct
      901 ggtttaagtt caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc
      961 aaaaaagctg catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta
     1021 cctgcattga atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat
     1081 tttgaagcac tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca
     1141 gcctatgcta tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca
     1201 actatttttg ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc
     1261 ataggtttat tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt
     1321 cgtccgaacg agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt
     1381 tatgaagaac tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg
     1441 ttgaggggaa attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt
     1501 cgttatgttt ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat
     1561 tttggtatga cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct
     1621 ttgacttttg ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc
     1681 aaagattttc gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg
     1741 atcataggaa caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc
     1801 aaagtgatcg gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac
     1861 tcgcttgaag agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca
     1921 ggtgaaaacg atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc
     1981 ttgattaata cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa
     2041 agcaatcatt tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc
     2101 cgatccttca agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg
     2161 taccctagag ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat
     2221 atgatttcga caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat
     2281 gaggtatctc ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa
     2341 aatgtttaaa aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta
     2401 tgggataatt cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat
     2461 tcataacagg ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct
     2521 tgttctacta aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga
     2581 gccagttctt ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt
     2641 aaagtcagtt ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga
     2701 gtggtgtggt tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt
     2761 gtctgagaga aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt
     2821 ttgatcaaat aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct
     2881 gcagcagtga tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa
     2941 tggataccac tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt
     3001 ctgaaatatt tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg
     3061 atgctttcca caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg
     3121 acatttgtca tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc
     3181 atttgtttgt ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag
     3241 attcaatcca aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc
     3301 tgagatttct tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc
     3361 ttctgtgtca tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac
     3421 ggcttctttt gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc
     3481 atccatctcc attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc
     3541 tttggcttcg tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact
     3601 tgagacttgg ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac
     3661 ttcttcatac ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc
     3721 atgggtttga gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa
     3781 tttcattact tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct
     3841 aaaaagaggt gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg
     3901 aacggtcgtt tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat
     3961 ttttttccta cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt
     4021 gtattgatca agaggatagt tttatcagaa gagatggcta agattccttc atctacttca
     4081 ttttcgataa tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc
     4141 agtacttttt tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca
     4201 ataatcaatg aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg
     4261 tttgttaagc caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa
     4321 tagcggaagc cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc
     4381 acttttttca catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga
     4441 gaatatcgaa tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg
     4501 atttcatttg ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg
     4561 atgagtttat cattggcaac gattttagca atgctagaga ttttatctga cacactagat
     4621 cggttcatcg aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat
     4681 gtggagaaac aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa
     4741 aaaggaaaca taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa
     4801 atttaacaaa ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta
     4861 aaagaagcta tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg
     4921 tgtatatgat agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg
     4981 caggattggc agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg
     5041 atccgatgct tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc
     5101 gtttaacaga tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt
     5161 tggtattttt gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt
     5221 cgtcttctga aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac
     5281 gaggtatggg agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt
     5341 tttacagccc ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca
     5401 aggaaagaat ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt
     5461 gttaaatgga aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga
     5521 tgttgctgat cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca
     5581 tcagtggaag ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca
     5641 aaattgtgcg tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca
     5701 gtctattatc gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac
     5761 cggtgatgtg tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta
     5821 cagcagcaga acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag
     5881 tattagaagg acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa
     5941 atcgcgataa gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg
     6001 ggttgatcat cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact
     6061 ctttagggaa accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag
     6121 ctctaaaaga aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat
     6181 tacagcgaca aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct
     6241 acaaacaaga acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg
     6301 cccgagcaca acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa
     6361 aacaaatcga actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag
     6421 tgaagaaaaa agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag
     6481 tcaaagaagt gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg
     6541 aagccaataa gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa
     6601 aagcagaagc cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag
     6661 ctgtcttgag tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc
     6721 taggaaatat cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg
     6781 gagcgaaccg agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa
     6841 aagcgacaac aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta
     6901 ctagccaagt aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag
     6961 aataaagtag tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc
     7021 tctccatttt tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt
     7081 tggatcttag cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt
     7141 tcgaccaaat cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa
     7201 ttgataccga ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac
     7261 aaagcggatt cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa
     7321 atgataccgg aattattgtt aataccatct gacacgacga tcacaataat aactagaata
     7381 ggaagcaaga tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa
     7441 atgatagcta atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg
     7501 gttgtagtca agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt
     7561 cctcgttgag tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc
     7621 gtacgcatac ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt
     7681 actatcatac ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa
     7741 taaaaaaggg ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc
     7801 ttcttttcga tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc
     7861 attgcattat taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga
     7921 atcgcagcct ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat
     7981 actatttttg gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa
     8041 ttaaccgaag ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac
     8101 atgtcttggc agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct
     8161 ttgcttgcaa atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag
     8221 atcgaaaaag aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat
     8281 aaagaagatg tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa
     8341 gatgccagag aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac
     8401 ttctctatga gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga
     8461 atccagcaac cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa
     8521 acattttcag agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta
     8581 ttgtatcggc aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg
     8641 ttccagtttt tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa
     8701 aaaatccaaa aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac
     8761 aacctcttct ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa
     8821 caaacatgag aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct
     8881 cacaacctct ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa
     8941 acgaaaaata ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct
     9001 ttttcacaac cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt
     9061 cgatgacatc ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta
     9121 ccatattctt tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct
     9181 ttgtaccatc tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca
     9241 cataaccgtt ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc
     9301 tgacagcagc aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc
     9361 ctgtttcaaa aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac
     9421 gagcgaaaga tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat
     9481 tgaagaaccg gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt
     9541 ttaaagcccc cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt
     9601 tgaagattgt catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt
     9661 cagccagttc ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt
     9721 ccaatgctgc caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt
     9781 cgatttcagc atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac
     9841 ggtgagcgaa gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg
     9901 tctcttgatt gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc
     9961 attgatattt tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct
    10021 attattataa caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat
    10081 gaaagcagcg atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag
    10141 gggataaacg tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt
    10201 gaaactgaaa aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa
    10261 tggaaagatg gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc
    10321 actgattatg aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa
    10381 aaacgaaacg ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg
    10441 cttagcagca aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt
    10501 agataccttg acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg
    10561 aattttcgtc tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc
    10621 gattgggtga atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa
    10681 gaacaacgaa aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat
    10741 gatcgcagca atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa
    10801 tcaagcagtc gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac
    10861 aaccagcagc aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga
    10921 tgttaaaaca gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga
    10981 aattgatgag tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat
    11041 tgctccagaa tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat
    11101 ggtctcagct taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga
    11161 tgtgatgagt cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat
    11221 tacggagcca ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa
    11281 ctggtacaac agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc
    11341 taaatggatc gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca
    11401 cgaagatata actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa
    11461 cgctgagtat atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga
    11521 aaagtaggaa ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg
    11581 ttggccagca gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa
    11641 gaatctgtct tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca
    11701 atttattgaa cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc
    11761 tagtatcatt ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag
    11821 caaatacaat aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga
    11881 aacaaaggaa tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga
    11941 ttcatgggaa cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa
    12001 tcctgcgctg tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt
    12061 gcaagatgca ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga
    12121 gacgtatcaa ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa
    12181 caatttacgc cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc
    12241 attttagaag caagcgggat caagatattt ggaaaattga tccgttcgat catctttact
    12301 acggatattg cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt
    12361 acacctcatc cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc
    12421 ggtgtaggtg gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa
    12481 gcgcaaggtt cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa
    12541 gtttgtcgag tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata
    12601 gatgaaaagt tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca
    12661 gaagcagtac gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt
    12721 ccaacggaag aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg
    12781 ccaccaagta gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa
    12841 aagaatcatg aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc
    12901 tcgtcttttg tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt
    12961 ttttttacct gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa
    13021 caaaaaaatg tcttgattta ttaaagcgct ttctatagaa tgaaaaacga ataaaaacta
    13081 aaaaaggcac ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga
    13141 actgaccaat caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat
    13201 ttcatacaga attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca
    13261 tgcttattta gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt
    13321 aattatcctc ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact
    13381 atctaatttt tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct
    13441 tggtttttat tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt
    13501 atattgaaaa ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat
    13561 cttagcttta agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa
    13621 aatcacgctg aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt
    13681 aatcgagctt tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta
    13741 tgaaggatat tacacaaaat tacgtacact agcagcatca gatgatatct gggacatttt
    13801 ccaactgaac aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt
    13861 ggagcaaggg ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta
    13921 cgacgggcaa ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa
    13981 aaatatattt gaacaattaa atatccctga accagcttca aattggacat gggatgaatt
    14041 tgaacaaatc agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga
    14101 agattttata gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta
    14161 taatcgggaa gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt
    14221 tttccagctg cgtaaaaatc tggtaaacaa aggggcccat ccagaaccag gtggtggagc
    14281 tgcaagtacg acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt
    14341 tctatcaagt aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca
    14401 gttgattaat ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc
    14461 gcaaatgctg agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga
    14521 tttctttcaa aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat
    14581 catgtcgaat attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt
    14641 tgattattta gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc
    14701 tttgaatccg gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga
    14761 agtaacagca gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata
    14821 gcagcaggag gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt
    14881 ggtcggttac gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc
    14941 gatgatcttg tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg
    15001 gatcggcttg gataattata taaagatgct gagtgatgcc cgttttttga actccatccg
    15061 agtcactttt ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat
    15121 tgcttatctt ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt
    15181 gcctagtttg atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa
    15241 aaacgggtta gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag
    15301 cgatcaaaaa ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc
    15361 aatgatcatc tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga
    15421 gatcgatgga gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc
    15481 gatcattttg tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc
    15541 atttatcatt acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta
    15601 taaccaagct ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct
    15661 gttgattatg ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt
    15721 gtgaatgaga ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta
    15781 ttttgctatt aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta
    15841 aaacggatca agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg
    15901 aaaattacgc aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga
    15961 attcgtttgt catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg
    16021 cttacgcatt atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag
    16081 taacgatgat gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc
    16141 tgaatttggt tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt
    16201 tcatttacca gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga
    16261 ttattgacgg atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac
    16321 cttcgatcat cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac
    16381 cattgattta tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg
    16441 cagacgctgg atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc
    16501 taccggtttt tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa
    16561 gcggtctgaa gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa
    16621 ctactatgtc tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt
    16681 tctaggatgt ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta
    16741 ttttttgatg atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt
    16801 atgttggagg aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt
    16861 tgtcattatt tttgcagttg attggtattt attagtggga aagattggag cttggtatct
    16921 gattcctttt ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat
    16981 tgatatctgc aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg
    17041 gctgttgtca aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt
    17101 ctggtgtata cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt
    17161 cacagtattt tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa
    17221 gtcggacttg gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa
    17281 acttgtgaac tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg
    17341 atacttgtga acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag
    17401 caactactgg atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat
    17461 catgattata tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg
    17521 actatcgatg aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc
    17581 ctgcgagtca cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata
    17641 gaaagtgatg tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa
    17701 cacggggcag attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt
    17761 gttcataaat ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa
    17821 aaggtatttg cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga
    17881 gtagaaatat tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct
    17941 atagacctgt cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt
    18001 ggatatattc gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc
    18061 gtaacggtca aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg
    18121 tgggaaggat tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc
    18181 gaaaagtctt acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag
    18241 tccatccatg tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg
    18301 ggcggacatg gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa
    18361 gaagatccgt ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga
    18421 atcgcagcaa atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc
    18481 ttaaaagaat aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt
    18541 attgccgata ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt
    18601 tttgtcatgc cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact
    18661 atttaaaccc gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata
    18721 agtaaaccac gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa
    18781 cattttttat tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa
    18841 tttacactat tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt
    18901 tctagccagt accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt
    18961 tcttatgata aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa
    19021 agcggttatt tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga
    19081 acgtattcaa aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt
    19141 cactcaccaa gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt
    19201 taaagaacaa ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt
    19261 atttgctgca agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac
    19321 gatggatgaa gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac
    19381 gatttctatt tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt
    19441 cttggcaaac ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca
    19501 agtagaagga atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga
    19561 agaaatggga ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt
    19621 tgagtttctt gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg
    19681 gttttagggc tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg
    19741 atcggtacag gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc
    19801 tttatgtgtg gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc
    19861 ttgcctgtcg ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc
    19921 aatgaaggag taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta
    19981 gtttctggtg tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt
    20041 atcaccgtta ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat
    20101 gcaacagcag ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc
    20161 ctaattgtag gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt
    20221 ggtttagtcg gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt
    20281 ggagatgcgc cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac
    20341 gtatggtcga ttttactaat gatcctcatt tccatggtca gcatggtaga atcaacaggt
    20401 gtatattttg cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag
    20461 ggatatcgtg cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat
    20521 actggctttt ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc
    20581 atctatttct ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta
    20641 gcacaaatca tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg
    20701 gcagtccaag gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg
    20761 attgttgctg tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt
    20821 caaatgccgc aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg
    20881 gctatcatat tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa
    20941 gccttcaaga agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt
    21001 tagagaaaca aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga
    21061 gggtcagctg attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag
    21121 tcacaaggaa caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac
    21181 cgaggagttg gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc
    21241 acattccttt tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat
    21301 tcgaaatttc tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg
    21361 aggaaaaaca atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac
    21421 aatgaaagaa gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt
    21481 ttctgctcat cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg
    21541 aatcaaaatc attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc
    21601 aaaaacaact ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga
    21661 ttcgcttctt tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg
    21721 aaaagcggga gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt
    21781 agaattggag gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag
    21841 tagtgatcaa cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg
    21901 gtcaattagg tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc
    21961 tggatcctgt gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct
    22021 atgatgacac ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat
    22081 tcgaaaacgt cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag
    22141 ggacagactt gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga
    22201 ataacatcgt gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga
    22261 ttgacgggat cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg
    22321 ggcagtatgt tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag
    22381 gaacctgtgt tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag
    22441 gaaatggtca aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata
    22501 ttcttcatga aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc
    22561 gtattgcccg tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt
    22621 ttttaacaaa aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg
    22681 gacattattc tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt
    22741 gtggttggcc attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt
    22801 tgggagaaca actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc
    22861 atttctatgg aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga
    22921 cagaagacat ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga
    22981 gaaaaaacat gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga
    23041 acaaataccg tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg
    23101 gtgaaatccc gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc
    23161 ggatcttgga aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt
    23221 ctgaaacatt gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg
    23281 tagatactgc ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga
    23341 aacgttttac ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg
    23401 gtcggacaca cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt
    23461 attcagaaat gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag
    23521 gaaaaatctc aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg
    23581 tatgtaaaca attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc
    23641 tacatgctga atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa
    23701 cagagatacg cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag
    23761 gtcaaaaagg ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg
    23821 ctggtctagc cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat
    23881 ggcatgaaag agatatttct cattcttcag cagaacgaat catcttgcct gataccacga
    23941 ttttattgaa ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc
    24001 ctgaaaacat gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta
    24061 tgctgaaatt gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa
    24121 aaactgcgta cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa
    24181 ccatcacatc ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt
    24241 tgaaaaacgt tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca
    24301 aaattcaatt aaaatagaat agcaaaaata accaaaaaag aagcagatcc gttagcggtt
    24361 ctgcttcttt tagtttatta tattttctta tcaataatag gaacctgatt ttaaaagcgg
    24421 ctacctcttt accgtgcctc tttacataca aaaaatagag gaattaagcg taaatggctt
    24481 ggctattata actaaaatgc tggttatgga gatgttgcag caagttttcg agaaaagcgt
    24541 attccatctc ttgtccattg aataagatct ggatacgata atgatttttg aaacgcttct
    24601 gttcatgaat ctgactgatt gaaagttcgc ctttgtgttc tgtctgataa agaaaagtcc
    24661 ttttacggca ttcagcacag cgcttggttg ctcggcggat ttttcggaat gtataaaaac
    24721 tagtatcttt attgcataaa taaacgtctt tgatcgacag caaatcatta tatagacagg
    24781 aacgttcttc agctgttaat tctgataaaa aaagctgacc ttgttttatt gcatcttcca
    24841 tcggcaagtg cctcctcgaa cccattatcc aaatttttag ttaattctaa tataccatca
    24901 ttaagtataa atgtaaacgc ttgttgatgg tataagattt tcgtttctga taaaacacga
    24961 acattaaaag aatctaatgc cttaaatgta catatttttg ttgatttata aaaagatgat
    25021 tgctaaaatt taaagtgaaa aaacgaacaa aaaacgatgt atttgctttt aatgtaaata
    25081 aaaaggagag acgtacatgg agaagaaaga acttttgtat gaaggaaaag ccaaaaaaat
    25141 atatcttact tctgatgaga acttgatttg gatagaatat ttagatcaag caactgcgtt
    25201 gaatggcgcg aggaaagacc agataagtgg aaaaggagaa ttgaataatc aaatcacaag
    25261 tgcaattttc cgttatctga ctcaaagagg aataaaaaat cattttattg aacaattgtc
    25321 taaaaccgaa caattagcaa aaaaagtaca aattatccct ctggaagtgg ttatccgaaa
    25381 tattgcagca ggaagtttct caaaacgtct aggtgttccc gaaggtaaag aattcatcaa
    25441 accaatcatt gaattctact ataaggatga ccagttggat gatccattta tcaatgaaga
    25501 gcatatctat ttcttacaac ttgcaaagcc ggaagaaatc agtgagctga aagcccaagc
    25561 gttggctatt aatgaaattt tgaccgaatt atttgctaag gtcggtttgg ttttagtaga
    25621 tttcaagcta gaatttggcc ggtcgaatgg acaaattttg cttgcggatg aagtaacacc
    25681 ggatacttgc cgattatggg atgaacgtac gaatgaacat atggacaaag acgtttaccg
    25741 cagagatcta ggtgatttga tcccagtcta tcaagaagta tataaccgtc tatcggaact
    25801 aactgaagaa aaggagcgag tatgatgtat ttcgtaaaag tatatgtaac ctataaagat
    25861 tcagtgttag atcctcaagg ggaggcagta aaaaaagcag tccatcgtat gggatatgaa
    25921 acaatcgaag atatccgaat aggaaaatac tttgagatac aacttgctga tgcagaagaa
    25981 ccaatcgata cagtgattga aacgatttgt gacaagctgc ttgcaaatgt aaatatggaa
    26041 acataccgat atgaaatcaa aaaaatggag gaagtataac atgaaatttg cggtcatcgt
    26101 ttttccaggt tcaaattgtg acgcagatat gttatgggca gttcgcgaga tcatgggcgc
    26161 tgatgccgaa tttgtacggc atgatgagtc ctctttagaa ggatttgatg gggttttact
    26221 gccgggagga ttctcctatg gtgactattt gagatgcggt gcgattgctc ggttttctac
    26281 aatcatggaa gaagtgattc gttttgctga agaagggaaa ccagtattcg gtacatgcaa
    26341 tggattccag atattgacag aagcaggact tttgccaggt gtactgagac gaaatgagtc
    26401 tttgcatttt atttgcaaaa ctgtaccatt gaaagtcaac cccaagacgg cctttacttc
    26461 agagtatgaa gccgacgaaa taatctatct tccagttgct catggggaag gaaattattt
    26521 ctgtgacgaa gaaacacttc aagaactaaa aaaaaataat cagattgcct ttacttataa
    26581 tgacaacatc aacggcagcg tggaaaacat tgcagggatt acgaacaaag cagggaatgt
    26641 gttaggaatg atgcctcatc cagaacgtgc agtagaagac ttgctaggat cagaagatgg
    26701 gaaacggttc tttgcttcca ttttaaaaaa cttcggaaag gtgaccgtat agatgaaaac
    26761 attgaaagaa ccgacagctg aagagatcaa gaaaaaaaga atctatgccg aatggggatt
    26821 gactgatgaa gaatatcgaa tgatcgaaga agatatctta ggaagaatgc ctaattatac
    26881 ggaaactgga ctgttttctg ttatgtggag cgaacattgt tcctataaaa attctaaacc
    26941 ggttctacgc aaatttccta ctagtggacc tcatgtgttg caaggccctg gagaaggcgc
    27001 aggcatcgtc gacatcggtg atggactagc agttgtcttc aaagcagaaa gtcacaatca
    27061 tccttcagcc gtggagcctt atgaaggagc tgcgacagga gttggcggaa tcatcagaga
    27121 tattttcagc atgggggctc gtccaattgc gttgctagat tcattgaggt tcggcgaatt
    27181 agataatcca agaacgaaat atttactaga agaagtagtt gcaggtatcg gcggatacgg
    27241 caattgtatc ggcataccga ctgtaggcgg cgaaattgca tttgatcctt gttatgaagg
    27301 aaacccatta gtcaatgcaa tgtgcgtagg tttgattgaa cacaaacata tccagaaagg
    27361 gcaagccgct ggcgtcggta attcgatcat gtatgtaggt gcaaaaacag gtcgcgacgg
    27421 tatccacgga gcaacttttg cctcagaaga atttaatcaa gaagaagaac agcaacgttc
    27481 tgctgtacaa gtaggcgatc cttttatgga aaagctgctg cttgaagcgt gtttggaatt
    27541 aatcttgcat cattcggatt ctctaatagg tatacaggat atgggagcag caggacttgt
    27601 ttcatctagt gcggaaatgg cttcaaaagc tggctcagga cttatattga cattagatga
    27661 agtcccacaa agagaaactg ggatgacacc ttatgaaatg atgttatcgg aatcacaaga
    27721 acggatgttg atttgtgtta aatcaggaga ggaagaaaaa atccaagaac tatttcagaa
    27781 gtatgatcta gatgcagtca ctatcggtaa agtaacagac gacgggcaat atcggctata
    27841 tcatcaagga gaagaagtag caaatctgcc agtcgatgca ttagctgaag atgcaccagt
    27901 ttatcataaa gaaatgaaag aaccagctcg aatcgtagaa tttcagcagt tagctcctta
    27961 tcagccagtt atcgaagaac ctggacaagt attgcttgat ctgctgcagc aaccgacgat
    28021 tgcttcaaaa cgttcaatct acgaaactta tgattcacaa gtacaaacca atacagttgt
    28081 ccgtccagga agcgatgctg ctgtgatgag ggttagaggg acgaataaag cgttagctat
    28141 gaccacagac tgcaacgcgc gctatctgta tttggatcca aaaatcggag gacaaatagc
    28201 agtggcagaa gctgctagaa atattattgc tagcggtggt aagcccttgg cgatcaccga
    28261 ctgcctgaac tatggttctc ctgataaacc agaagttttt tgggaattat cgacttcagc
    28321 tgacggaatt gctgctgcgt gtgaaacgtt aggaactcct gttatttcag gaaatgtctc
    28381 tttatataat gaaacggatg gtcaagcaat ctatccaaca ccaatgattg gtatggtcgg
    28441 attgattgag gatcataaac atatcactac tcaggaattc aaaaaatcag gggatctaat
    28501 ctatatatta ggtaagacgt ttgcagattt tgatggcagt gaattacaaa agatgcagct
    28561 tggaagaatc gaaggtgtga tccgaaactt tgatctatcc attgaaaaga gaaaccaaga
    28621 gttagtattg acagccatcc aaaacggatt gattgaaagt gctcatgact gttcagaagg
    28681 tggcttggca attgcactgg cagaatcagc tttcaaacat cagctaggga tatctgtaca
    28741 gtttgaattg tcctctgctc aattatttgc agaaactcaa tcaagatttg tgttgacagt
    28801 cgcaccggaa aataagacac gattcgaaga aatgatggga gatgctgctg ttttagcagg
    28861 taaggtgacg gatgaagcga taatcgaaat ttcagcaact gacggtcaga tcaaaataga
    28921 aactgcagta gcaagaaagt gctgggagga tgcaatcgta tgtcttatga agtgaagagt
    28981 ttaaatgaag aatgcgggat cttcggtgtt tggggtcatc cagacgccgc tagtgtggca
    29041 tacttcgggc tccatagtct tcagcatcga ggacaagaag gtgcaggtat cgtgtccaat
    29101 gatcgaggaa agcttaaggg gcatcgagat ttggggctgc tttctgaggt attcaaagat
    29161 caaagaaaat tgcagcagtt aacaggagaa gctgcaatcg gacatgtacg ttatgcaaca
    29221 gcaggcaatg gaagtgtgga caatattcag ccttttctat tcaaatttca tgatcagtcg
    29281 atcggcttag cgcataatgg taacttgatc aatgctcgtt cccttagaaa agagttagag
    29341 gaaaatgggg cgatcttcca ttctaactcc gatacggaga tattgatgca tttgatccga
    29401 cgaagtgaag aaacagattt tttaaataaa ttaaaaagtg ctttgaatga agtcaaaggt
    29461 ggctttgcct atttattaat gacagaaacg gcaatgattg ccgctttgga cccaaatggt
    29521 tttcgtccat tagcaatcgg acaaatgaaa aacggagcat acgtgattgc ctcggaaact
    29581 tgtgcattag aagttattgg ggcacgtttt ataagagatg tccagcctgg tgagatagtg
    29641 atcatcaatg acgaaggaat ccagattgat tgctttacga aggacacgca gctttctatt
    29701 tgttcgatgg aatatatcta ttttgccaga ccagattcaa acatcgcagg gatcaatgtg
    29761 catactgcac ggaaaaatat gggacggaat ttagcgaaag aatcgccagt aaaagcagat
    29821 atggtcgttg gcgtacctaa ttcttctttg tcagccgcaa gcggttatgc ggaagctagt
    29881 ggaatccctt atgaaatcgg attagtaaaa aatcaataca ttgcccgaac atttatccag
    29941 ccaacgcctg agctaagaga gcaaggtgtt cgaatgaaat tatctgctgt acgaggagta
    30001 gtggaaggta aaaaggtgat tatggtcgat gattcaattg ttcggggtac gacaagcaga
    30061 cggatcgtcc atcttttgaa agaagcaggg gcaaaagaag tccatgtgag gattgcttct
    30121 cctcctttga aatatccatg tttttacggg attgatattc aaacgcgtaa agaactcatt
    30181 gcggcaaatc acacgattga tgaaatcaaa gaatgtatcg gtgcagattc tttaggtttt
    30241 ttaagtgaag agggtctgat cgaatcgatc ggtctggaaa aagatgctcc gtattcagga
    30301 ttgtgtatgg cttatttcaa cggagattat ccgacgccgt tatatgacta tgaagaaaaa
    30361 tatcaggaat cactaaaaga aaaagtatcg ttcttttaaa agcagaccaa gaagggagta
    30421 tatgaattca atggcaaatg catacgcaaa agctggcgta gatgtcgaag ctggatatga
    30481 agtagtagaa cggatcaaga agcatgtcaa aaaaacggaa cgtttaggta tgatgggcgc
    30541 tataggagga ttcggcggtt gttttgattt atcggtcttt caattaaaag agccagtcct
    30601 tgtctcgggg accgatggcg tggggacgaa attagcagtg gcaatcgaag cagacaaaca
    30661 cgatacaatc gggatcgact gcgtagcgat gtgtgtcaat gatatcttag cacaaggcgc
    30721 agagccgtta tatttcttag actacttagc aacggggaaa aatgatccgt tacgtttgga
    30781 aaatgtagta aaaggtgtag cagatggatg tgttcaagga aatatggcgc tgattggcgg
    30841 agaaacagct gaaatgcctg gtatgtactc aggtaatgat tatgatctag ccggatttgc
    30901 tgtagggata gctgaaaaat ctcaattatt gacaggagaa acgatcaacc caggagatgt
    30961 gttgcttgga atagcatcta gcgggattca ttcaaatggg tactctcttg ttcgcaaaat
    31021 tttctttgag cagcagcagt tttctttatc atcaaaactg ccagaattga aaaaaacact
    31081 tggcgaagaa ttgcttgagc caacgaaaat ctatgtttct tccttgcttc cgctgatcaa
    31141 agaaaagaaa ataaaaggag ctgcacatat cactggtgga gggtttgtag aaaatatccc
    31201 gcgaatgtta ccagaatcta tggctgcaca aatcaaactt ggctcatggc cgattcttcc
    31261 aatattcggc tgtttacaaa aatatggtga aattcctgag atggagatgt atgaaatctt
    31321 caatatgggc atcggtatgg tcctggcagt cgaagaatcg aaagtaaaag aaatagtaca
    31381 cgaaattgag caagctggcg aaaaagttta tgaaatcggg aaagtgatcg ccaaagaaaa
    31441 acatcgtgtg gtgtttatag gagaagaacg atgagaatcg ctgtttttgc ttctggaaac
    31501 ggaagcaact ttcaagcgct agccgattat ctatcgaaaa aaggattgga atcttcgatt
    31561 gactggttgt tttgtgatca gcctgaagca tatgttttga aacgtgcaac tgcgttgagt
    31621 gtaccggcag attgtttttc acctaaagaa tttgattcaa aaaaagagta tgaagaagca
    31681 attttgcata aattgaaaga aaaaaagatc gatttgatcg tattagctgg atatatgcga
    31741 atcattggac cggtattgct gaaaaattat gataaaagaa tcatcaatat ccatccgtct
    31801 cttttacctg ccttccctgg tttgcatggc atacgtgatg cctttgaagc tggagtaaaa
    31861 gaaacgggtg tcacaattca ttatatcgac caaggtgtag atactggacc aatcatccgg
    31921 caggaaaaag tgagaattga acaggaggac acgttcgatt ctttagaaga aaaaatccat
    31981 agagtagagc atcgaatcta tccagaagtg attagtgaaa ttattgaaaa tggaggctat
    32041 ctgaaatgac aagagcattg atcagtgtat cagataaaac tgggattgta gcattcgccc
    32101 aaggtttgat tgaacaagga gtagaaatca tttcaacagg aggaacaaag catgcgttgg
    32161 ataaagctgg gatcaaaacg ctttcgatcg aagaagtgac agggtttcct gaaatgatgg
    32221 atggccgtgt caaaacactt catcctaaaa tccatggtgg tcttttagga agacgcgatc
    32281 tccctagcca tatggaggca atggaaacgg aaaatatcca accaatcgac tttgtttgtg
    32341 tcaatttata tcctttcaaa gaaacgatta tgaaaccaga tgtcgaaata gcagaagcta
    32401 ttgaaaacat tgatatcggt ggtcctagta tgctccgtag tgcagcaaaa aaccatgaat
    32461 ttgtcacctc tgttgttgat ccatctgact atgaagaagt actttcagaa ttacgtcagt
    32521 atgggcatac ttcactttct ttcagacaaa aactagcggc aaaagtcttt cgtcatactg
    32581 cggcatatga tgcactgatc gctcaatact taacggattg ggtggaagaa aaagaaccgg
    32641 aaaaattgac acttacgtat gaacgaaaac aaacgcttcg ttacggtgaa aatagccatc
    32701 aagccgctgc cttttatcag tccgctcttc tggaaaaata ttcgatcgca gcagcaaaac
    32761 aactccatgg gaaagaactt tcttataata atatccgaga tgcagatgct gcgctacgga
    32821 tcatgaagga atatgacgag ccaacggtag tcgccttgaa acacatgaat ccttgtggta
    32881 ttgggacagc atctacgatt ttagaagcgt gggaagcagc gtatgaagca gatcctgttt
    32941 caatctttgg tgggatcatc gttttgaatc gagaagtaga tctgccaaca gcagaacaga
    33001 tgcataagct gtttctagaa atcatcattg ccccttctta tacacaagaa gctttggaat
    33061 tactgcaaaa aaagaaaaac atccgattac tgacagtaga ctttgcgcag gaagaaaatc
    33121 aaaatcgaga agaaacggtc tcagtcttag gtggacttct tgtacaagat caagatctgg
    33181 caatagaaaa tgaagaagag tggaaagtcg tgacaaaacg taagccgact ccagcagaag
    33241 caaaagcatt agcgtttgct tggagagctg tcaaacatgt gaaatctaat gcgatcgtac
    33301 tggcaaacga acgtcagaca gtaggaatcg gagccgggca gatgaatcga gtcggttcag
    33361 taaaaattgc gattgaacaa gcgcaagaga aaatggaagg tgcagtttta gctagcgatg
    33421 cttattttcc aatggatgat tcggttgaat atgcagccaa acatggtata aaagcaatca
    33481 ttcagccagg aggaagcatc aaagaccaag attctattga tatggcgaat aaatacgatc
    33541 tagcaatggt ctttactgat gttcggcatt ttagacatta gagaggagtc ggataaatga
    33601 acattttggt gatcggtgca ggtggtcgtg aacatgcaat aagtaaaaaa cttttagcca
    33661 gtccgaaggt ggatacggtg tattgtgcgc caggaaatcc ggggatgaca aaagatggta
    33721 tcaattgtgt cgctatcagt gagcgagatc attcagcgtt aatccatttt gttaagaaag
    33781 aggctattga ttggagtatc gttggtcctg aagttccttt gttaaatggg atcgtcgatg
    33841 attttatggc ggaaggattg aaaatcttcg gtccgacaaa agcagcagct ctgatcgaag
    33901 gttcgaaaag ttttgctaaa caattaatgg atacttatca aatcccgaca gctaaatcca
    33961 gaagttttga atgttacgaa aaagcagcag cgtatatcaa agaaaatggt gcgccaatcg
    34021 tagtgaaagc ggacggctta gcagctggga aaggtgtagt cgtggctacc acagtgaagg
    34081 aagcgctgga tgcggcagaa caaatgttga accagcatcg atttggggat agtagcaaaa
    34141 aaatcgtcgt agaagagttt ttggcaggag aagaattctc ccttttggcg tttgtccgta
    34201 ataccaaggt gtatccgatg gtcatttcgc aagatcataa gcgggcattt gataacgata
    34261 aagggccaaa tacaggcgga atgggtgctt attcaccagt accgcaaatt tcaaaaaaga
    34321 tgattgaaaa agctgtggaa gaagttttaa aaccagcggc tttgggaatg aaagaactag
    34381 gacgctcttt cacgggtgtt ttatatgcgg gtttgattgc tacgaaggaa ggaccaaaag
    34441 tgatcgaatt caatgcgcgt ttcggtgatc ctgaaacgca agtcgttctt tctcggttga
    34501 agagtgactt tgcgcaagta atcgatgatt tattagagaa tcgtacagta gagttaaagt
    34561 ggcagcaaga aggatacaat gtaggcgttg tggttgcagc tgccggttac cccgaagaat
    34621 atgagacagg aatggttcta ccagattttc tggaagaaga gctttctgtt tactatgctg
    34681 gagtttcctc aaataacggc aaactagttg gagcaggagg acgtctttat ttagtagaag
    34741 catacggtga gacgatcaaa gaagcacaga aaaaaattta caccgcgtta atggataaaa
    34801 cgacagatgg aacattttat cgtacagata ttggagaaaa agctgccaat agcgaactga
    34861 tcgtgaagta aatcagctgc ttccatttat aaaaaataca acaaacataa tcggaagcgc
    34921 cgattttagt gaagcctttt cataaagagt gtggtacact tttgttgtgt atataaataa
    34981 ggaggagttc agatgaaaaa aattcaatta ggtacttctg atcagaaagc agctgcagtg
    35041 atcttaggct gtatgcgtat caacaatgcg gaagatccag taaaagtgat tgagacagct
    35101 tatgaaaacg gcattgattt ttttgaccat gcagatattt atggaaacgg tgaatgtgaa
    35161 gaaatctttg cagatgctct agcaaaaaca tcaatcaaac gagaagatct ttttattcaa
    35221 acaaaatgtg gaatcgttcc aggtgtgatg tttgattttt ctaaaaaaca tatcattgaa
    35281 tctgtagaaa aaagtttgac ccgtctgaaa atggattatg tggatgcttt acttcttcat
    35341 cgtccagata cattggtaga accagaggaa gtagctgaag cgtttgatga attggaacgg
    35401 tcaggaaaag ttcgttattt tggcgtcagc aatcaaaaac caatgcaaat cgaattgctg
    35461 aaaaaatatg ttcgtcaacc attagtagct aatcagctgc aatttggctt gaaacatact
    35521 ggaatgatcg atcaagggat tcatgtcaat atgacagatg aagcaagtat cgatcatgac
    35581 ggtagtgtac ttgattattc ccgattgcat gatatgacga tccaagcatg gtcaccatac
    35641 cagtatggat tttttgaagg tgtatttatc gggaacgaaa aattccctga attaaaccaa
    35701 acattagaag aactagcagc taaatatcaa acgacaccaa ctggcttggc ttctgcttgg
    35761 attttacgcc atccagccaa tatgcaagtg atcgccggta cgatgaacgt agggcgaatc
    35821 aaggaaatcg ctcaagcttc agaaattaat atgtctcggg aagattggta cgaattgtac
    35881 cgtgctgctg gaaacatttt accttaaaga ttgtcataag caggtcaaaa gggctataaa
    35941 ttaaaaagac agaataactt gaaagctgtt ttcagcttcg agatattctg tcttttttta
    36001 ttgcaaatgg aaagagtatc attgtacgga tttcgtttat tagttatttt tgtttttaag
    36061 gaaaagctgt gtccgatatt cttttggaga aatcccttgt tttttcttaa ataaataact
    36121 gaaatagtta gggtcattat aaccaatttc aaaagcaata tctgaaatac gatagtctga
    36181 ttgctgcaat aatttttttg ctaattcgat tctttgttct gtcagataat cgatgaatgt
    36241 ttggttaaac gattgagaaa aaatcgtact gaaatgagag ggacttaatg caacttgttg
    36301 agcgacccaa gttaaggaca tatctggatc ggtaaaattt tctttgataa aatccaatgc
    36361 atggttcaaa attggctgat atttgttcct tgaaggctgt gagggcagag cagttaagaa
    36421 agaaatgaac atataaactg tcgaacggta aagcgagtcg tcggcgctga ttgctaagcg
    36481 ttgactggtg gatgtgcaat gaaccatttc ttgcgggatt ttcttttctt tcaggcagac
    36541 atgctggagt agcttagtca agacaaataa acgatataat cgtgttcgag ttggtgtgcc
    36601 ttgtggtttc gtcaagtgtt cgatgtactt agatacttcg tttttcgata atgaagacaa
    36661 atcaagtgag aggtcaaagt aaaagacaga atcaactgga agtttcgctt cttgaatcaa
    36721 atcctcatag ctgataattt gttctttaag ggaactggcg gtttcaagta tcatctgcgt
    36781 gatctcaaaa gatgcaggta attcgctgat tctttctgcg acaggaccaa tggcgacaga
    36841 aaaattattt ttttgtccct tttctaattc atggaccaac gtttgggcta cctgataact
    36901 ggtctcgatc acattttctt caagagaatc aactattaaa aatttgatga atcgagagga
    36961 aacagcagag aagatcactt gttgattctc cctaaataaa aacttcaaat aatcactgag
    37021 atgagcgtaa tcttcaaagt ctgtactgac ttggtttgct gctaataata cggtcatttt
    37081 tttccctgct aaagagcgat tgaaagattc agcaagtttc aatgtttcac tgatcgtaag
    37141 tgagcctttg aacaaaccgt tcaagaaatg attttttttc aattcgaaaa caagatcaga
    37201 agaagtgtgc gtttcttttt gctgcaaatc taaagcagtt actgcttttt ctattgcttg
    37261 tttcaattcg ctacttttaa tcggtttaag cagataatca tctgcctgta cctggattgc
    37321 tcctttcata taatcgaaat cgtcgaatcc actaataaat atgagacgag tccaaggaag
    37381 tagtttcctt gcttcttttg aaaaagtcaa cccgtccatg aaaggcattt ggatatcagt
    37441 cagaatgatg tcgggctgta agtcgataat tgaagacagt gccatctcac catctccagc
    37501 ttcgccgaca taagtgattg gataataaga accaaggaca gttatttgtt cccgcaagtt
    37561 attgcgaatg aggtattcgt cttcgatgat aaaaacttta tacatgtttg tttcctccaa
    37621 ttgttttggg agatagaggg atcatcagtg tgacagttgt tccttctcgg tatttgctgt
    37681 caatcgtgat aggtttttga tcatttccgt aataaagaag gagacgcttg tttacgttgt
    37741 aaagtccgta gccgatactg aaatctgaat cgatcccttt ggctaactct ttacgtattt
    37801 ctgccagttt ttctgcaggg atgccaatcc cgttgtctat aactttgaat tggatcatct
    37861 catcaatttt gcatgtggta atacgaataa atcctttgtg acggacgtac ttcgttccat
    37921 ggtatacagc attttcaatc aatggctgca agatcatttt taaaatagaa acaggaaaaa
    37981 gtgtttctgg tatatcgatc ttatagtcaa gcatatggcc gtatcttatt tttaagatga
    38041 ctagataatc attgatatgg ctaatttctt tttcaagagg aatccagtct tgtcctttgc
    38101 ttaaagacgt acgaaaaaag ccggaaagtg catgggtcat agtcagagct tcttcaaagc
    38161 agtcttgttc gatcaaagaa ataatggcat ccaaactgtt ataaataaaa tggggagtaa
    38221 tctgagcttg caatacacga acttcacttt gtgctaaatg gtattgtttc aaagcgttct
    38281 cccgtaaaga ctggtttaga tcttccgcca ttttattcat gctagcggta agtgtttgta
    38341 attccagtgt ttccggcagg gttaaacgaa agccaaggtt ccctgaagaa agttgttctg
    38401 acatctcgat cagctgattg atcggttctt ggacctttct ctctaaaaag cgacgattct
    38461 ttttcgcata gaaaaaaatg gtactaagaa ctccaagttc cactattgtt aatagaatga
    38521 gcgagcggac aagtgtcgta ttttttttgc ttgctaagtc gatctccaca cgaacaaaat
    38581 cttgtaagat atctgacagc agttgagtga cagaatctac ctgattgatg atctcttcat
    38641 tggtatccat aaaatctttt gccaagatat tattgatcag ctcgttttga taatcttcca
    38701 gtgtatcgat cgtacgtagc gatacatcta acgtactaat ttctttaagt gtatttgtat
    38761 tatttttgat ctctcgaata tcattcctaa gttcttctag gatattttcc tcattgaact
    38821 catctacggt tacttggcca gaaatcaagt cccacatact ttccaaaact ttttgatcaa
    38881 ccttcaaagc aattgcatct gctttttgga tatttgcgat cgtctgttga taaatcaaaa
    38941 gctgttgcga atataacagt atgctcagta gcaaagggat aacagcaaat agaagcatgg
    39001 ctttgtttgc ttgggcaaaa atctgtttta tgcttaaatt ttttgtcatg atacttctcc
    39061 agtcaataat ttctggttgg gatgttagct atattctgct gggaaaagac agtctcggaa
    39121 ataaaaatat ctttaggtaa tgtttttcct gtttgaatat ttccaaaata acgagtaacg
    39181 gtattggcta cataccagcc gacatcaggt ttacactcga ctacacaatt gacgattcct
    39241 gagcgtagct tctcgatcat atcttcttgt ccatcaatag ttacaatgat caaatcttct
    39301 ccaggtttga ttgatgtttc ttttatcgca gctaaagcac cgtgagtcat ttcatcacta
    39361 tggctgtata atacatcgat ttcggataaa tcatttgttt ctaaatatcg tttcatctgg
    39421 tcttttcctt tcatccgaat aaaatcaccg acaattcggt gaacaatagt catcggaggt
    39481 ttatggtcga tggttccatc tttttttagg gttggtttac gattgattga ttccaaaaat
    39541 ccttcggagc gtagcttggt cggtgtggag ttctctgaac cagcaagttc taggattctg
    39601 atttcctgtt tctttgaatt tgtgaagtga ttgctgacaa ataaacccgc ccgatttcct
    39661 tctgctttga aactggggcc aatgtgggtg acgaaaagct cgggatcatt cgtttgaata
    39721 tgtctgtcga caagtatgac agggatccct gctcgctttg cttcttttaa tacagagtcc
    39781 cacccggatt cttgcaaagg agtaaaaatg atcatatcca ctttataggc aatgaacgtc
    39841 cgtatatctt ggatttgccg ttcctgattc atgtagccat ttcggtagag aacttggtaa
    39901 tcttcttttt caagcgcagt gataattgat tcagtatgct ttttccgcca gctactctcc
    39961 gttcctgatt gcgaaaaacc aacgactagt gggtcaggtg cttcctttgt attaggtgta
    40021 caccccatca tttggtaagc gattacaaca agggctaaaa aaaataaaac acgtttcact
    40081 ttaaatcact ccatctggat ttgttagtac tatcttatca gataaaaggg aaaatcaaag
    40141 tcaaaaggaa tcaatcgaaa aaaatccaag aaacttaaaa aaatccaaga caaaaaaagt
    40201 acacctaaaa aatttaaagt aaatcccata aaaaaatcaa tgttaacgct ttctttatta
    40261 gctatactcg gtgtatcaat tgaaatgggg gataaaaaat gaaaaacaaa tttagaaaga
    40321 ttgttgggac tatcgctatt ttgaccgcaa gcattctatt aagtgcgtgt ggcaattcag
    40381 gatctgcaga tgatagtacg gggtatgtag gaatcgctat gccgaccaaa tcagcagaaa
    40441 gatggatcgc tgatgggaac aacatggtct cggaattaga aaaactgggt tataaaacag
    40501 atcttcaata tggagaagat aaagtagaaa atcaagtagc acaaatagaa aatatgatta
    40561 caaaaggggt agatacactt gtgattgctt ctatcgatgg ttcggcttta actgatgtgt
    40621 tagctaaagc aaaagaagca gatatcaagg tgatcgccta tgatcgttta ctgatgaatt
    40681 cagaaaatgt cgattattac gcgacttttg ataattttgg agtaggtgta tcgcaagcag
    40741 cttatattga agagcactta ggattgaaag aaggaaaagg accattcacg attgaattat
    40801 ttggtggctc gcctgacgac aacaacgcac taatcaatta caacggagtg atgtctgttt
    40861 tacaaccata tatggacaac ggtcagttgg tcgtgccatc tggacagacg agtttcagtc
    40921 aaatcgctac gcttcgctgg gatggttcta cggcgcaagc aaggatggat aatctgttaa
    40981 gcgcaaatta tactgaccaa acattggatg ctgttttgtc gccatatgat ccaataagtt
    41041 taggaatcat ttcgtcatta aaaggcgtgg ggtatgggag tgaaagtaaa cctttacctg
    41101 tgattactgg acaagatgcg acagttgctg gcgttaaatc gatcattgcc ggggaacaaa
    41161 cacaaacgat ctttaaagac acacgtatct tagcaaaaaa tacgattgaa atgatcaaag
    41221 caatcagtga tggagaagag gttccggtca atgatactga aacttatgat aatggggtga
    41281 aaactgtccc tacgtattta gcaaatacag tatctgtcga taaagataat tatcaagcag
    41341 agctgatcga caccgattat tataaagaat ccgatctgaa aaattaagag gaaccaaaca
    41401 aggaactaaa gagatctaag tcagagagag gataagaatt atggcggatt gtattttaaa
    41461 aatggcagat atcaccaaaa aattttctgg aatccgagcg ttagattgcg tgaatctgat
    41521 gattgaacgt ggggaaatcc atgcattgtg cggagaaaac ggagcgggaa aatcaacatt
    41581 gatgaatgtc ttgagcggct tgtatccata tggctcctat gacggggaaa tcttttatga
    41641 tggaaagctg tgtcaattta aagatttgaa agatagtgaa gaaaaaggca tcgtcatcat
    41701 tcatcaagaa ttagcactaa gtccttatct ttcaataaaa gagaatattt ttctcggaaa
    41761 tgaacaagca gaaagaggcg tgattgattg ggaactgaca gaaaagaaaa catatgaact
    41821 gctgaataaa gtcggtttgt ctatcgaccc gaatcttcta gtatcccaga ttggcgtagg
    41881 gcaacagcaa ctagttgaaa tagctaaagc attatcaaaa tccgtccgtc tgttgatttt
    41941 ggatgagcct accgctgcat tgaatgaaga agaaagcgcg aatttgctga gattgatccg
    42001 agagttgaaa gagcaaggtg taacctccat cattatttca cataagctga atgaaatcgt
    42061 ggatatcgca gatcgaatca ccattttacg ggatggacag acgattgaga cactagaaaa
    42121 tgaaatgatc agcgaagagc atattattcg cggaatggtg ggcagagatt tagttgatcg
    42181 ttatcctgaa agaaaaccgg atattggaga agtttatttt aaagtagaag actggacggt
    42241 ctatcaccct cttgatcacg agcgaatcat aaacgaccac atcaacttgc atttgaaaaa
    42301 aggagagatt gtaggaatag ctggactgat gggagcgggc agaactgaat tcgctatgag
    42361 tctatttgga cattcttatg gaagcaagat atccggacgt atattaaagg aaggggcaga
    42421 gatatcagtt aagaccgttc cttcagccat tgcaaacgga ctcgcttatg tctcggagga
    42481 ccgaaaatct ttaggactga atctgctgat ggatattcgg gaaaacgtga cgctgagcag
    42541 tttggataaa ataagtcaaa aaggagtatt agataaagaa aaagaagtaa ctgaggcaga
    42601 aaatttccgg aaaaagatgc gtataaaaac aaactccatc catcaaattg tcagtagtct
    42661 tagtggtggg aatcaacaaa aagtcgtttt atccaagtgg ctgatgacac aacccgatat
    42721 tctttttttg gatgagccaa cccgtgggat agatgttggg gcaaaatatg agatctacac
    42781 gattatcgaa gaaatggcag caaatggcaa agctgtctgt cttatctctt ctgaacttcc
    42841 tgaaatatta gggatgtgtg atcgaatcta tacgatgaac gaaggacgta ttacaggaga
    42901 agtctcgcga gaagatgcag atcaggaagt cttgatgaaa ttaatgacga aagaagaggt
    42961 gggttaagtt ggaacaggca aaaaatctta cggataaaaa agagaaaaaa ctaaatttga
    43021 aaagtagagc agctgatctt tttggtcgct acagcatggt gatcatttta gcgggactac
    43081 ttattgcgtt tcaattgatg acggatggta ttttctggcg tccattgaat ataactaacc
    43141 ttgttctgca aaatagccat atattagtac tagctgcagg gatgttatta gttgtgctct
    43201 taggtcatgt ggatttgtcg gtagggtcag tgatggcgtt tgttggtgca attgcgggca
    43261 tgatgatggt caatcgccaa atgaacccgt ggatgacagt tatcgcatgt cttgcagtag
    43321 gcgggctgat cggcgcatgg caaggttttt gggtagctta tgcagggata ccggcgttta
    43381 tcgtgacttt agcaggattg ctgatgtttc gtggactgac acaagttgtt ctaggaggcc
    43441 aatctctagc accttttcca gctgttttcc aaaaaatgtc tacgggttat ttaccagact
    43501 taagcgaagg aagcagcctt cacttcttga cattgatttt aggaatgatc atcacgatcg
    43561 tgttagttgt tggtcaatgg cgaacaagaa atcgtcggaa aaatcattta tttgaagtgg
    43621 aatctccaac agctttcttg gtaaaggcgg tatttacagc agtcgttgta ctaggaataa
    43681 cttatatctt tgcctcttat caagggtatc cgattatttt gatcattctt ggtttgatcg
    43741 ttgcagcata tgggtttttg acaaataaaa cagtagcagg tcgacagatt tatgcgacgg
    43801 gcggaaatcg aaaagcggct gaactatcag ggatcaaaac aaagcgaatc acgttctggg
    43861 tattcgtcaa catgggagtc atggcagctt tagctggatt agttttagct gctcgattga
    43921 atgcggcaac acctcaagca ggtacatcga tggaactgga tgcaatggcg gcagtatatt
    43981 ttggtggtgc ttcgacttcc ggcggcattg gaacaatcat gggtgcgatt gtcggtggct
    44041 tggtcatggg tgtattgaac aatggcatgt cgattttagg cgtcggggta gactggcagc
    44101 aggcaatcaa aggattgatc ttgcttttag ccgttgtgct agacttgtat aataagaaaa
    44161 aacgaacaac gtaggagaac gccggttatt cagaaaaaag actgtgacaa gacatttgtc
    44221 acagtctttt tttcgctaaa agcgaacatt cattgtttcg tttgtataga ctaaaaataa
    44281 tatatgtttt tttaccattc gtataaattc tctttttgct cttgattttt ttgcttaatt
    44341 gagttaaatt acatagggcg ctaaaaaaag ccttgattaa attaataatg ttcgtgtttt
    44401 gctggatgtg aacatcagga ggataatgta atgaaagtat ttgattacga agatattcaa
    44461 ttaattccta ataaatgtat cgtaaatagc cgttctgaat gtgatacaac ggtcacatta
    44521 ggtaaacata cattcaaaat gccagtagtg cctgccaaca tgcagacgat tattgatgaa
    44581 acaatcgcag aattcttagc ggaaaatggt tatttctata tcatgcatcg gtttgatgaa
    44641 gcagctcgaa ttccgtttat caaaaaaatg aaaaagcgtg gattgattac ctcgatcagt
    44701 gttggcgtca agaaagagga atattccttt atagagaagt tggcagaaga atcgctaaat
    44761 cctgattata tcactatcga catcgcgcat ggacatgcta actcagttat tgatatgatt
    44821 cagcatatta aaaaatattt gcctgaaact tttgtgattg ccggtaatgt tggtacaccg
    44881 gaagccgtcc gtgaattgga aaatgcgggc gcagatgcaa caaaagtcgg gattggtcca
    44941 ggaaaagtat gtattacaaa aatcaagaca ggctttggga ctggaggctg gcaactggca
    45001 gctcttagat ggtgtgcgaa agcagctcgc aagccgatca tcgctgacgg tgggatcaga
    45061 acacatggcg atattgcaaa atctgtccgt tttggtgcga caatggtcat gattggttca
    45121 ttgtttgccg gtcacgagga atctcctggc gaaacaaaag tcgaaaatgg aatcgtgtat
    45181 aaagaatact ttggttctgc ttcagaattc caaaaaggcg aaaaacgaaa tgttgaagga
    45241 aagaaaatct ggatccaaca caaaggatct ttgaaagata cactagtgga aatgcaacaa
    45301 gaccttcaat catctatttc ttatgctgga ggaagagatc tggaagccat tcgaaaagtt
    45361 gactatgtca tcgtgaaaaa ttcgattttt aatggagaca caatctaaaa aataaataaa
    45421 atattaggat gttgtgaaaa agttgtcctg cattaagtaa taagaacagc caaacaaaaa
    45481 tagttcttta tatgttttgt ttggctggaa ttattatcgc agatacaagc ttttgaacat
    45541 cattattcag aataagggac tgtgataaga tttttgtcac agtcccttat gttttgcaaa
    45601 aaaagttttt cttttttctc gtaaattcgg taaaatcaaa agaaaaaata gacaatagaa
    45661 aagagaagct tatgtgggaa aaagtagaga aaaaacaagg accgatttat cgtcaaatta
    45721 tggaacagat tatgagagaa atcgaaaacg gaaggatcaa tcctggaagt caacttgaat
    45781 cagaacgaaa actagggcaa ctttttggtg tgaatcgttc caccgttgtc catgcattgg
    45841 aagagcttag ggagcttggg gtactaacga gcaaacgtgg cagcggatgg tttgttaatc
    45901 agactgaatg ggggaaattc gctgttccaa gaatcgattg gcggcaaatg atctctcctc
    45961 gttatgagca gacggactgg tatgagcaaa aaataagaga agcaaagcag atccaaaaaa
    46021 catcgtttct tgatttatac gctagcgaga tgccagatga gcttttgccg aattttgagt
    46081 ttccttctta ttctcttgaa gaaatcttag cggaagaaaa agaaatggat cttttaggct
    46141 atactccgtt acgtaacaaa atcaaacggt atttggaaag taaatttgaa ttggcatttt
    46201 cccccaacca gcttcttgtg actggtggcg gtcagcaagc aatctttttg attttacaaa
    46261 cgattctttc agctggagag gggatagctg tagagtcacc ttcttttttt taccgattac
    46321 ctcttttcaa agcttcagga acgcgtttat ttgggatacc gatggatgaa gaagggatcg
    46381 acttagaaaa actgaaagaa tcgatccata aaaataaatt gaaagcagtg cttatcaacc
    46441 cgaattttca aaaccctaca ggaaaagtga tgagtcaaaa acgacgagaa aagctagtag
    46501 aattgtgtcg acagtatcgg cttccaatta ttgaagacga tgtatttacg gatctttcat
    46561 ttctaaacca agaagaagtc cttcctatac gaacgattga tccggataat gtgttatacg
    46621 tcggttcgtt atctagggtt ttaggaaaaa caacgaaaat cggttgggtg ataggacctg
    46681 agacttttat ctcgcaacta gctcaagcgc aagaaatgat ggagttttcg atgaatatcc
    46741 ttacacaaat cacagtggct aatgtattta atgaagcaat tgatttgaaa atgcaagatg
    46801 taagaaaaaa gttgaaagaa aaaagccgac tgataagcgc ttggggagat tcacaatcgt
    46861 ttttcaagct tcattcaatt ttaggtggtt actatgcctg gattacttgg gatgggaaaa
    46921 aactagaccc cgaactagca gaaaaagtag tagatatggg tcttggaatt gcaccaagtc
    46981 tactttttgg gcaagatata aatggaatca gaatcaatta cagtaggctg gatgaaaacc
    47041 aaataccgtt gttttattca aagatgaaaa ttctagaaaa gtggttaaca gaataatttc
    47101 acaaagtaaa tagattaaag aatataacag cttggattta aatttcaagc tgtttctttt
    47161 ttttcggaaa aagaatacga tataaagaaa ctaagaaaaa accattattt gtacgtccgt
    47221 tcacgatgtg taaataaaat aaatgtttgc aacaaaactg tataacacca acgtttttaa
    47281 atagaaacag atggttgtaa gtttgattag aaaatagaaa aaatgcagat gaaatataaa
    47341 acgctttcct tattgtgatt ttattcacta atgctgttaa tatgcggatt ggcataattt
    47401 cctttcatcg tgaaaatttg tgcttttagc ttgtatttct cataaatcca tgataattta
    47461 ttaatgaaga cggttaaata gtgatacagt tttattcact gtttcaatcg cagaatgaag
    47521 agattttctt atagatgaga gaggaatgtg tgacaaatgg caaacaaaaa agcaccgatc
    47581 gacttccaag cactgctaga tgaagtcaat gcagatttcc cagtatatca agcacttgat
    47641 caagatggaa acgtagttaa caaagattta gtacctgatt tatccgatga tgaactcgtt
    47701 gaattaatga ctcatatggt atggtctcgt gtattagacc aacgttcaac agcgctgaac
    47761 cgccaaggac gcctaggctt ttttgcacca actgctggac aagaggcaag tcagctggct
    47821 agtgcttacg catttgataa agaagatgtt cttcttccag gttatcggga tgtacctcaa
    47881 ctagtaaaac atggtttacc tttatctcaa gcttttttat ggtctcgagg acatgctgca
    47941 ggtaattctt atccggaaga attgaaagct ctaccaccac aaattatcat cggtgcacaa
    48001 tatgtacaag cagccggtgt tgcattaggt ttgaagaaac gaaacaagaa aaatgtcgtc
    48061 ttcacttata ctggtgatgg cggttcatca caaggtgatt tttacgaagc aatcaatttc
    48121 gctggcgctt accatgcaaa tgccgtattt tatatccaaa acaacgggta tgcgatctct
    48181 acacctcgtg aaaaacaaac tgcagcaaaa acacttgcac aaaaagctgt cgcagctggg
    48241 attcctggta ttcaagtcga tggaatggat ccgcttgcag tatatactgt atctaaaatg
    48301 gcacgggaat gggcgatcag tggaaatgga ccagtcctaa tcgaaacact gacttatcgt
    48361 tatggaccac atacactatc tggtgacgat ccaactcgct accgtacaaa agacacagat
    48421 gacgattggc agaaaaaaga tccattgatc cgcttccgta aatatttgac ggaaaaagga
    48481 ctttggtctg aagaaaaaga agaacaagtc atcgaagcaa ctaaagaaga aatcaaagca
    48541 gctattgctg aagccgacaa agtaccaaaa caaaaggttt cagatttctt gaaaaacatg
    48601 ttcgaagtat ctccacaatc aatcaaagaa caaattgcaa tttatgaagc gaaggagtcg
    48661 aaataatcat ggcacaaaaa acaatgatcc aagcaatcac agatgcctta gcacttgaac
    48721 tagaaaatga cgagaatgtc gttgtttttg gtgaagatgt tgggaaaaac ggaggagttt
    48781 tccgggcaac tgaaggattg caggaaaagt tcggagaaga ccgagtattc gatactcctt
    48841 tagctgaatc tggaatcgca ggattgagtt tcggtcttgc gttagaagga tttcgtccag
    48901 ttcctgaaat ccaattcttt ggttttattt tcgaagcaat ggacgaagta gtagctcaaa
    48961 tggctcgtac aagatatcga atgagcggca ctagaaatct acccatcaca attcgttcgc
    49021 catttggtgg cggtgttcat acaccagaat tgcattcgga taatttagaa ggtttgatcg
    49081 ctcagtctcc tggtattcga gtagtgattc cttccaaccc ttatgatgca aaaggactat
    49141 tgatttcttc tattagaagt aacgatccgg ttgttttcct agaacacatg aaactatatc
    49201 gctcattccg agaagaagtg ccggatgaag cttacgaagt tcctttggat aaagcagcag
    49261 ttactcgtga gggaacagat gtatctatta tcacatacgg agcaatggtg cgtgaagcaa
    49321 tcaaagcagc agacaatctt gcaaaagaaa atatatctgt tgaaatcatt gatcttcgta
    49381 cagttgcgcc attagatgta gaaacgatca ttcaatccgt ggaaaaaact ggtcgcgtag
    49441 ttgttgtcca agaagcacaa cgacaagcgg gcgttgccgc gcaagtagtt tctgagatct
    49501 cagaacgcgc tatcctttca ttagaagccc caatcggacg agtttctgca cctgatacag
    49561 tcttcccatt tggacaagca gaaaatgtct ggttgccaaa tgcaaaagat atcgaagaca
    49621 aagtaaaaga aatcgcggaa ttttaagaaa agaagggacg aaacaaagtc atggcttatc
    49681 aatttaaatt
//
LOCUS       DACGLI010000016        48759 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.017, whole genome shotgun sequence.
ACCESSION   DACGLI010000016 DACGLI010000000
VERSION     DACGLI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.017"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(10..2082)
                     /locus_tag="IXT22_000987"
     CDS             complement(10..2082)
                     /locus_tag="IXT22_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4862369.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLNLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERIPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(2015..2392)
                     /locus_tag="IXT22_000988"
     CDS             complement(2015..2392)
                     /locus_tag="IXT22_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAQ4862370.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(2521..3081)
                     /locus_tag="IXT22_000989"
     CDS             complement(2521..3081)
                     /locus_tag="IXT22_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4862371.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINDFIATLP"
     gene            3231..4523
                     /locus_tag="IXT22_000990"
     CDS             3231..4523
                     /locus_tag="IXT22_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4862372.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMSFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(4583..5701)
                     /locus_tag="IXT22_000991"
     CDS             complement(4583..5701)
                     /locus_tag="IXT22_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAQ4862373.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVNPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(5715..7136)
                     /gene="arcD"
                     /locus_tag="IXT22_000992"
     CDS             complement(5715..7136)
                     /gene="arcD"
                     /locus_tag="IXT22_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAQ4862374.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(7382..8503)
                     /gene="mnmA"
                     /locus_tag="IXT22_000993"
     CDS             complement(7382..8503)
                     /gene="mnmA"
                     /locus_tag="IXT22_000993"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAQ4862375.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGDMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            8907..9506
                     /locus_tag="IXT22_000994"
     CDS             8907..9506
                     /locus_tag="IXT22_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAQ4862376.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELITQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(9644..10930)
                     /gene="efmA"
                     /locus_tag="IXT22_000995"
     CDS             complement(9644..10930)
                     /gene="efmA"
                     /locus_tag="IXT22_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAQ4862377.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11201..11545)
                     /locus_tag="IXT22_000996"
     CDS             complement(11201..11545)
                     /locus_tag="IXT22_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAQ4862378.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(11682..12818)
                     /locus_tag="IXT22_000997"
     CDS             complement(11682..12818)
                     /locus_tag="IXT22_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4862379.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(13006..13980)
                     /locus_tag="IXT22_000998"
     CDS             complement(13006..13980)
                     /locus_tag="IXT22_000998"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4862380.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(14060..14935)
                     /locus_tag="IXT22_000999"
     CDS             complement(14060..14935)
                     /locus_tag="IXT22_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAQ4862381.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            15065..16972
                     /locus_tag="IXT22_001000"
     CDS             15065..16972
                     /locus_tag="IXT22_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAQ4862382.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(17390..20680)
                     /locus_tag="IXT22_001001"
     CDS             complement(17390..20680)
                     /locus_tag="IXT22_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAQ4862383.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGPDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERLTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNQATGEVLENAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     ASYETKEILHTVDYRKPNYSTVYVTPEGSDTGNGSRQNPLSLTQALRYAYAGQTIVLA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWVLR
                     GFDVTNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVVIK
                     NSVAYRNGWVPGVEGEGNGNGFKMGDSSLSGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDFHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTHSQEGQQPVTRYANGSIHVHGLMQIKPEN
                     RQTEKGRVDGLPLSVGATFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVV
                     YVMKQRKK"
     gene            complement(20951..21496)
                     /locus_tag="IXT22_001002"
     CDS             complement(20951..21496)
                     /locus_tag="IXT22_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4862384.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(21508..22200)
                     /locus_tag="IXT22_001003"
     CDS             complement(21508..22200)
                     /locus_tag="IXT22_001003"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAQ4862385.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(22219..22503)
                     /locus_tag="IXT22_001004"
     CDS             complement(22219..22503)
                     /locus_tag="IXT22_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862386.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(22516..23079)
                     /locus_tag="IXT22_001005"
     CDS             complement(22516..23079)
                     /locus_tag="IXT22_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4862387.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            23307..23969
                     /locus_tag="IXT22_001006"
     CDS             23307..23969
                     /locus_tag="IXT22_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAQ4862388.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            24093..25289
                     /locus_tag="IXT22_001007"
     CDS             24093..25289
                     /locus_tag="IXT22_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAQ4862389.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(25390..26766)
                     /locus_tag="IXT22_001008"
     CDS             complement(25390..26766)
                     /locus_tag="IXT22_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862390.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVIILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(26803..27669)
                     /locus_tag="IXT22_001009"
     CDS             complement(26803..27669)
                     /locus_tag="IXT22_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAQ4862391.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(27758..28783)
                     /locus_tag="IXT22_001010"
     CDS             complement(27758..28783)
                     /locus_tag="IXT22_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4862392.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(28801..29475)
                     /locus_tag="IXT22_001011"
     CDS             complement(28801..29475)
                     /locus_tag="IXT22_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862393.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(29659..30552)
                     /locus_tag="IXT22_001012"
     CDS             complement(29659..30552)
                     /locus_tag="IXT22_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4862394.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(30626..32323)
                     /locus_tag="IXT22_001013"
     CDS             complement(30626..32323)
                     /locus_tag="IXT22_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4862395.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(32316..33629)
                     /locus_tag="IXT22_001014"
     CDS             complement(32316..33629)
                     /locus_tag="IXT22_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4862396.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(33629..37666)
                     /locus_tag="IXT22_001015"
     CDS             complement(33629..37666)
                     /locus_tag="IXT22_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4862397.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(37679..38137)
                     /locus_tag="IXT22_001016"
     CDS             complement(37679..38137)
                     /locus_tag="IXT22_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4862398.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(38434..38952)
                     /locus_tag="IXT22_001017"
     CDS             complement(38434..38952)
                     /locus_tag="IXT22_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4862399.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(38954..39571)
                     /locus_tag="IXT22_001018"
     CDS             complement(38954..39571)
                     /locus_tag="IXT22_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4862400.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(39568..40422)
                     /locus_tag="IXT22_001019"
     CDS             complement(39568..40422)
                     /locus_tag="IXT22_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4862401.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(40419..41330)
                     /locus_tag="IXT22_001020"
     CDS             complement(40419..41330)
                     /locus_tag="IXT22_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862402.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(41371..42705)
                     /locus_tag="IXT22_001021"
     CDS             complement(41371..42705)
                     /locus_tag="IXT22_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4862403.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            42913..43743
                     /locus_tag="IXT22_001022"
     CDS             42913..43743
                     /locus_tag="IXT22_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAQ4862404.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(43987..44236)
                     /locus_tag="IXT22_001023"
                     /pseudo
     CDS             complement(43987..44236)
                     /locus_tag="IXT22_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(44427..44621)
                     /locus_tag="IXT22_001024"
     CDS             complement(44427..44621)
                     /locus_tag="IXT22_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862405.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(45126..45311)
                     /locus_tag="IXT22_001025"
     CDS             complement(45126..45311)
                     /locus_tag="IXT22_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862406.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(46161..46502)
                     /locus_tag="IXT22_001026"
     CDS             complement(46161..46502)
                     /locus_tag="IXT22_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4862407.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(46502..46732)
                     /locus_tag="IXT22_001027"
     CDS             complement(46502..46732)
                     /locus_tag="IXT22_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4862408.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            47019..47357
                     /locus_tag="IXT22_001028"
     CDS             47019..47357
                     /locus_tag="IXT22_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862409.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(47562..47801)
                     /locus_tag="IXT22_001029"
     CDS             complement(47562..47801)
                     /locus_tag="IXT22_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAQ4862410.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(47777..48124)
                     /locus_tag="IXT22_001030"
     CDS             complement(47777..48124)
                     /locus_tag="IXT22_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAQ4862411.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
BASE COUNT        14167 a        10397 c         8540 g        15655 t
ORIGIN      
        1 catatcttat tatttcttca ttgccgcttt tagtgctgct gctaatgggc tttcttctgg
       61 ttcttctgct tgtgcatatt ttttcagcaa gcgtcgttct tcatgtttgg tcattttctt
      121 cttctgctct tttttatcaa gcattttttc tgtcgttcca tcgtatttac aacggaaata
      181 agcaccgttt ttaccttcga tgatttccat tttccggtga cattgcgggc atcgatgatt
      241 agagactttt ggatcttttc ttctgcggta gttgcaatct gaattggtgc agacatagat
      301 tttgccgtca cgtgtgtttt tctcgcgcag attggcccca cattctgggc atttcttttg
      361 ggtaatcgag aaatcttgat attcttgttt gcttgatttg atctcattca ccaagcgttt
      421 tgtttctttt tcgattccat tcaagaaggt tcctgcttgt ttctttcctg cagcaatagc
      481 ttcaaggtct ttttcccagc tttctgtcaa atctggtgtt actaaagagg gatttaccaa
      541 tactaataat tgcttacctt taggagatac ttgcagtcct tgagggatac gttccatcag
      601 ttcagatttg attagtttct cgataatctc tgcacgcgta gctggggttc ccagactgta
      661 tttttccatt tgaccaagca agcttgcttc tgacaatggt ttaggcggtg cagatagttc
      721 ttttttgatg gcgaaatcgg gattgattct cattcctttt tcccatttga ctgtttccgt
      781 ctcagtttca gtttcgcctt tccatcctgc ttggacgaca cgattttgcc gaaaaatgaa
      841 tcgttcttta ccaaattcaa ccgtaacttt tgtttggctg actttatggg gttgagcaaa
      901 cagtcctaaa aaacgagaga caatcatttg atagattttt tgctcttcat tacttaattt
      961 ttcataacgt gctctgtttt cagttggcaa aagtgcatgg tgatcggtca ctttactgtc
     1021 ttggaatact tttgtctgtt ggacgatggc tccgtttttc aaatactgct tgacctcagg
     1081 agcaaagtcg ctgactgctt gcaatcgttc tttcatcgta cttttcatgt catttgtcag
     1141 atatttgctg tctgtacgcg gataagtaac gatcttatgg gtctcataca aactttgtac
     1201 aagatttaat gttttctttg cagaatagcc atagcgttga ttggcttctc tttggatctc
     1261 tgttaaatca taaggcaatg gcgcagattc cgtttttaat ttttcttgga cttctgtgac
     1321 agttcctttg cttgtactga tcaattgaac aagtttttgt gcttcttctt gtgtttttaa
     1381 agcaaattga tttttttgaa gcattttggc ttgttctttt ccagcttgca acgtgatcgt
     1441 gaaatacgtt tgtggacgga actgctcgat tttcttttct tggtctctca ctaatgctag
     1501 tgtcggtgtc tgcacacggc ctgctgataa attatccgcg tacttcacag ttaaggctct
     1561 ggtcacattc aatcctacca gccagtccgc ttttgcccgg gcaagagcag attcatacaa
     1621 tgcatcatat tctttcgcag gtcttagttg cttgaatcca gttttgattg ctttatctgt
     1681 ttgagaagag atccataacc gcttcactgg tttattgaaa tgcacatact ctaagatcca
     1741 gcgagcaaca agttcccctt ctcttccggc atctgtcgca atgactgctt ctgagacatc
     1801 ttttcgctga gctagctgct tgattgcttt taattgatgt cctgttttag gaagtggttt
     1861 gattcctagt tttttaggga tcattggcaa cgtgtccatt tgccagctct gccattcctt
     1921 attcagatct tccggcattt tcaatcctaa taaatgacca agggcccaag taacgatcac
     1981 cttgggtcct tcataataat ttttgtgctt ttgattagca ccaagcacct tgcttaggtc
     2041 tttcgcaacg cttggttttt ccgctagaat tagttgtttc ataaaattcc tttccgcttt
     2101 ctactgtgat gggctgatga tttttcaaca acgcaagtcc tttgtattgc tgtaaatcat
     2161 cgtcacactc ttcacaccag cgctcatctc cgtcattcca aaaggcgctg agaaagttac
     2221 tttttgcatt gatatattca taattttgat ggatttcgtt ccattgtttt tcgtacgctt
     2281 gtcgtgcttc ttcgaaagac tcgaatgttt cttctgcttc aatatcttct tcccagtctt
     2341 caaaaaacca ccaaggctca ttgtccccga acatggtaat tacttgatac atactcgtgc
     2401 tccttctttc agcttttcta gactcatctt agtcactttt caagaaagtt gcaagaattt
     2461 tctcttataa aagggtcatt taatgaacat cttaaaattg ttacaaatga atctgattgt
     2521 ttaaggcaaa gtagcgataa agtcattgat catccaaaaa tagctgtctt ctggatcgat
     2581 tgttggttct tttgtaaagt atcctaaaaa acgtaaggaa agataaccgt ggatcatact
     2641 acgaagttcc ctgcttcgat gaactttttc ttctttcgtt aattgaaaag cctcaaatat
     2701 ctgcaaaatg atctgattcg tttcatggat tccatctaat aaaacagctt cattggtatg
     2761 cggtacactg atcagtaact catacactgc ttgatttgaa aaagcaaagg atcgataagt
     2821 ttctgcatag atctgcagtg cttcctgacc actttttcct acaagagccc gacgcagctg
     2881 gtcattaagt tcctgcagaa gtttcgctgt tagcgctgtt ttgacatcac gaatattttt
     2941 gaaatggtta tacagcgagg gagccttgat atccaagcgt ttggctaaat gctgaaaggt
     3001 tatttgctga acatccatct cttctgctag ttctcgaaag cagtcgatga ttttctcttg
     3061 agacagattt ctttttttca tttccatgtt tcctctcata aaataaatcc ttcactcttt
     3121 cagtttacca cgaaaaagaa agagaaaaaa gagactttca ttgataaact acatattgta
     3181 gtttataata aagatctgta gatgaaaatt ttcagaaaga aggagtctaa ttggctgcaa
     3241 gaataaagga aaaattattt aggaaaagag aaacttggga acaaaacttg tttgtcttat
     3301 ggtttggaac atttatggct ggtatcggat ttagtttagt catgcctttt atgtcacttt
     3361 acatagatac gttaggtaat tatagtacgt cacaattgaa cttttggagc ggattgactt
     3421 tttcatctac tttcttggtg actacgctga tctctccttg gtggggaaaa ttagccgacc
     3481 aaaaaggaag aaaattgatg ctgttgcgtg cttcattagg aatggcaatc gtcatttctt
     3541 tgatgggttg cgtgactagt gtgtatcaat tagtcgcatt gcgtctgctt caagggattt
     3601 tttctggtta tatcagtaat gccactgccc ttgtcgcaac tgggacgcca aaagaaaaaa
     3661 gtggtcaagt tcttggaacc ttagcaactg gttctgttac aggaacatta cttggaccgc
     3721 ttcttggcgg gatctctgct tcagcgtttg gctatcgccc tacctttttc attacaggga
     3781 tcatcttatt tttcgtcttc ttgttgagtc tgtttttcgt ccatgaaaaa tttgtcccag
     3841 tgaaaaaaga aaacatggtt tctgccaaac agattttcaa agacttgaaa tatccacacg
     3901 tcgtcatcgg tatgttcgtc acaacgatga tcatccaagc atccaacaat tccattagtc
     3961 caatcatcag tctgtacatt cgccaattgc tgcatggaca tgggaatgtt acgttgatca
     4021 gcggaatcat cgcttcgata cctgggattg ccactttgat agccgctcca agatttggtc
     4081 gcttaggtga caagatcggg agtgaaagaa tacttgcgat tggtttgggt tttgcgattc
     4141 tggtttatat cccaatgtca ttcgtcacga atgtttggca attagctgcc ttacgttttt
     4201 tgattggtat ctctgatgct tgtctgctcc ctgctgtcca agcattgatc acaaaatatt
     4261 cgcctcatca agctgctgga cggatcttca gttataacca atctttccaa gcaactggta
     4321 acgtagtagg gcctatgatc ggctccagtg tttccagtgc atttggttat cgtggcgttt
     4381 ttctttcgac ttctcttctt gttttggtca acttcttgct tgtacgacac aatacacaag
     4441 aaatccatca gcaagaaact gcagaagaaa aagcttcagg agtctccata tcttcagggc
     4501 actctccttc tcatagacaa taagcgtaaa tgaaaaacac tgcttgaaca gttgtcacag
     4561 actgtccttg cagtgttttt gtttaggcct gttttttcaa gaactcagat aagaggaata
     4621 atcccttttc caaggtttct tttttacaac agtaacctag tcgggcatgc ttcggtaaat
     4681 caaaggcact tcctggtact aatagtactc ctgtttcttc taataaattg atacaaaatg
     4741 tctggtcatc ttcttcgatg gctaatttaa tgaaagaagt agagacgtaa ttgggagcga
     4801 caagttcaac tttcggttca ttggctaccc attgttttaa aatcacaagg ttctctgtaa
     4861 tgatcttttt gtttcgctcc aatatttttt ctttattctt caatgcatgt acagcaagat
     4921 catctgacag gactccgccg caaatcatcg tgtagtctcg atactttcga aaaacttctg
     4981 ccaactcagg tccagtagct gtccagccaa tacgaatacc tggaatggag taggttttgg
     5041 atagggaatt ggttgctata cctttttcat agacatctac gatcgacaag aattcacctt
     5101 tatccgttaa aggcgcatat acttcatcta tcaatacata tgcatctact gtacgagcaa
     5161 tttctgcgat tttttctaaa gttttccgat ctagcaatgt gcctgtagga ttgtttgcac
     5221 tattcaaaca gatgattttt gtttcaggtt tgactaaggc ttctagctgt tctaaatcaa
     5281 actgccaatc ttcttcttcc ttcaaatgaa caaagtcaac agcggcacct aaagatttgg
     5341 ggatgtcata taattgctga taagtaggaa gcatcgaaac aacatggtct cctgcttcca
     5401 ctaacgcgta tagagctaaa agattagcac cagtcgctcc attcgtttgt aagatgtttt
     5461 ccggattgac ggtttgataa agagaagcga cttcttgttt gaaaacatct gatccttcga
     5521 tccagccata gtccaatggt tcgtttttgc gtttttcgaa aaattcactt acgctagtcc
     5581 catctaagcc aacgagttcg tctaatgtca atgcttcgat cgagctttgt gcaatatcat
     5641 ataccgcttt cttttcccat ttatttagcc attcttctac accgaaattt gcgattttca
     5701 tgtttctttc ccccttatat cttgatccag cctacagcaa gcaacccgat tgaaagcagt
     5761 gcggccacac aaatcagccc aatcattact ttttcttttc ccgtaatttg atgtttggtt
     5821 tcacgacaag cgatccagta gaagcaaaaa ccaggaagat aggcaatact acataaaagg
     5881 acataagaaa atcctgctaa aatgatgccc atcaattcaa aaactacagc aatcccaccg
     5941 atcactactt gttttttgat tccttctttt aaagaaaact ggacttgata gatcccgaca
     6001 agtagataac aaatcaaaat tgccgctgta cataaagaat aggcaaattg ataggcataa
     6061 tcagtaacta agaaagtcaa taagaataga ttagtcaaga ttgcagtaac aactaacgaa
     6121 taagttgggg catttttttt attcgttttt ccccaacctt tcggcaacag accgtctcga
     6181 gccatcaaca tcgttgtttc tgctgggagc atcgtccaag acaaccaaga accaatgatc
     6241 gaaataatca agccgatatt gatcagcgct gctccccaat ttcccacgat tccttttaaa
     6301 atatttgcca tagcaggttg tgaaatagtt gctaactctt cttgagataa gacgccgtat
     6361 ggcaagatcg aagcaaggat atagataaac aataaacaaa gcagaccaat gatcgatgct
     6421 tgctgggctt ctgaacgttt cttcgcgcgg ttggctaaaa cacttgcgcc ttcgatccct
     6481 acaaagaccc acatcataac catcaaacaa cctttaatct gcaaccagat cgttccttgc
     6541 tgccctgttc cattcactag attatcagat acgttacccc aaaaatcagc agtgaatata
     6601 ttcactttaa atgcgataaa tacaaatatt aaaaatagga ataatggcac taatttacag
     6661 atcgtcacga ttgtattgat gacgctcgct ccttcaactc cattgtttac taataaagtc
     6721 agaccccaaa taaaaatact tgcaaataaa atagaaggaa cattttgtcc acctttgaat
     6781 atcgggaaaa attctcccat ggcgctcatc agcatcgttg caaaggcaac atttcccagc
     6841 cacgcagaca accagtaacc ccaaccactg atgaagccac ctaatttacc aaatgaagct
     6901 tccgcgtaac cgaaaatacc accatctaga tctggacgtt tttctcctaa atgattcagc
     6961 gataatacca aagctaaaat accaatccca acgattatcc atgaaaggat cgctggccct
     7021 ggagctgcag aactagccag atcacttgtg atcccaaaca caccgcttcc gattgacgaa
     7081 ctgacaacca gagcaaccag tccccatttg ctaatacccg tcgatttctt ttccatttcc
     7141 atcaccctca cttataaaat tgaacaaatc acttgcaaaa gattcccttc tattttgcaa
     7201 ctgctcttgc ttaacaaaaa gcaactttat tcatattatt ggatattatg aactttttac
     7261 acaagtattt caagtataaa atgaataaaa attaatttta ttgcaaaaaa acagctatgc
     7321 tatccaaaag aaaaggtgtt tcttttgtta gccatagctg ttttgattca tttaatatcg
     7381 cttaaacgta ttgtaaaact tttgtttctt gatatgcgtg gtcgatcaaa ccaccaccca
     7441 gacattccat tccatcataa aatacaactg cttgtccagg agtgattgca cgtacaggtt
     7501 cgtcgaatac gacttctgca cgattatcat ccaataagcg aactgtcaca ggaacgtctt
     7561 gctgacgata acggaatttc gctgtacact tgaattcttt tggcattggt tcattcgtcg
     7621 taaagtggat ttcacttgca tccaagcttg tggcatacaa tgcaggatga tggaaccctt
     7681 gccccacata taatgtgttt gtcgctagat cttttcctac aacaaaccag ggttcttgcg
     7741 aatctcctcc gccaccgatc cctagtcctt gacgttgacc aatcgtataa tacatcaagc
     7801 cagcatgttg tcctttgact tcaccatcaa gagtgaccat atctcctttt tttgctggca
     7861 gatagttgct caaaaattgt ttgaagttct tttcaccaat aaagcagatt cccgttgaat
     7921 cttttttctt agcagtcgca aggcctgcgc gttcagcaat tgcccgtact tctgattttt
     7981 ccatgccgcc tagagggaac atcgtttttg aaagctgttc ttgtgataat tggctaagga
     8041 agtaagtttg atctttatta ttgtctactc cacgaagcat gtggaccacg ccgttttcat
     8101 cgcgagtgac ttgcgcataa tgtccagtag ctacataatc ggcgccaaga tccattgcat
     8161 aatccaagaa tgctttgaat ttgatttctt tgttgcacat cacgtctggg ttaggtgtac
     8221 gtcctgcgcg gtattcggct aggaaatatt caaatacacg atcccaatat tctttttcaa
     8281 aattcacaga gtaataagga atcccgattt gagcagctac tttcgctaca tccttataat
     8341 cttccgtggc cgtgcataca ccgttttcgt ccgtgtcatc ccaatttttc atgaatattc
     8401 cgatcacgtc gtatccttgt tcctttaaca aaagtgctgt tacagatgag tcgacaccgc
     8461 cgctcatccc tacgacaacg cgtgttttgc tgttgtctgt catgatatca ccatcatttc
     8521 aattagattc tgaaacatct acgagttgaa ggtcgcaact tttcagtatt ttacattata
     8581 cgtcatattt ctgaaaattt catcccttaa ttatcaagtc gtaaaaatac tgttctactg
     8641 gacctattca gtacacaaac atgatagtca accaaaaaat cactcatctt ttgagcattc
     8701 gatataaaaa attggcatac tcataaaaag ggccagcctt tcggcaataa ggaataattt
     8761 tgtaaattgt gaaaaactat ttttcaaaat tgcttcttat cgcttaaagc tgcacgtctc
     8821 atttacaacc ttttcttttt agatgttatg agttgctcag ataagtgatt ttgtttactc
     8881 taagaaaaaa gggaggcaag agatacatga attactttac cagtgatatg cactttttcc
     8941 atgaacgctt attaggaaaa aacgactttg ctccgcggct ctttgcaaat gtggatgaaa
     9001 tgaaccaaca gttgatcact agctggaatg cagtaataaa agaaaccgac catgtttatc
     9061 atctaggcga ccttgctatg catccgcaat atgaaaaagc aaatgcagaa attttggaac
     9121 tgatcactca actgcaagga acaatccact tgatcaaagg gaaccatgac agtcgtgctt
     9181 ttttccgtta tttagaaaaa aatgatccta ggcttactga cggaagtccc aaattttatt
     9241 tttatgatgt aggtgccatc gttaaattcg accatcaaca atattacttg actcattatc
     9301 cgatgttgct cgggcctaac gacactatcc gcaatcttca tggacatatc catcattaca
     9361 gcgtacctat cgagaacgat gtcaatgtag gcgtagacgc accggaaaga gaactcttaa
     9421 aggaaaaact accatttggc actccgttat ctgagcaaca aatcaaagaa atctatgaag
     9481 caaagaggaa gtacgatagg tcgtgaaaaa actgccctat atcaagtatt aaacaaataa
     9541 agataattac tcatattttt catttgagta ggcttattgc cacaggaaca ttaggatcag
     9601 aaatggagtt gtaacaagac ttctgtcaca actccattcc atactattcg tctttttgct
     9661 catggtgttc ttttaccaat tttttctgta attctttatc ataatttcga gcagctgacg
     9721 ttaaaaataa aacgattccg cataataaaa tcccgattcc agaaaacaag aacatttttt
     9781 ctactcctaa acgatcagct aatggtcctg caaataataa tccaattgga cctgccaggt
     9841 tcatcaaaga gttgaagttc cctaagacac gacctaaaac attcgattca taactctgct
     9901 ggatcattgc catcagcagt gtattgaaat atggcgttgc acaacctgct cctgcattca
     9961 agataagaaa gtacaagaac ccttgactat cgtttggaac caatccgctt gcaccgatcg
    10021 tcaggcccat aatgatgtag gctataataa taggtttcat tcggtctttc catgttccta
    10081 taaaactgat cagtgcaccg cctaagagca ttccgactgc gtagactact tccactgctc
    10141 ccgcctgtcc aacggaacca ccaaagtaat ctagcgtcat caatggatac agactgattg
    10201 ctggcatgaa caacagcatc acaaatgcac cattgatcgt tatgtaccat aaccctttgt
    10261 tatccatcaa ttgctgcagc ccaaattttg catctttaaa aatagtaagc ggaacttcca
    10321 atatttcagg agaaactttt gggatcttca caaaaatcaa taagccgaca ccaaaaactg
    10381 cccccaatac atctaataaa ataaggtaat tgacaggaac gactgaaaac aaagccgcac
    10441 ctagagctgg cgcaatgatg aaattcgctg actggaccat tcctaactgt ccattcgtcc
    10501 ttgttatgtg agaagatgga acgattgtcg gcataatcga ctggatcgtt ggcatttgga
    10561 atgtttgtgc gaccgaacgc ataaacaaag acacaaaaac tagccaaatc gggaaggatt
    10621 ctgaaatcgt tccgactact gctaaaataa gcgcgaaaat cgctacaata atatccgtga
    10681 caatcaaaag agctttttta tcccagcgat ccactagcgg tcctacaaat gggcttagta
    10741 aaaccatggg aatcattcct agtaaagtag caaaactcaa aattgtcgcc gaaccggttt
    10801 ctcttgtcaa ataccagatg atcgcatatt ggacgaccat actagtgatt cctgacaaaa
    10861 actgtcccga taaaaagaac aaataatttc tcttccaatt cgttaaaacg accgactgtt
    10921 cattttccat aaacatccct cttttctttt tcattttgta tagcgtttgc acaacaatca
    10981 ttatacggga ttcttttttc aaaaaatacc tttttcccta aataacaatc gtttcaattt
    11041 aaatttcttt acttagaaac aataaatcag caaaatatta aaaataacaa catgtgttaa
    11101 atttaaaaat aaaaaagaca actaatttgc gtcgtcctta caaagttagt catctaacaa
    11161 taggccgttt caaaactagt tgtcttttta tatccacaga tcattcgact ttttcgaata
    11221 acccacggct aatcatccca tccatcagaa aataaaattt atcttggctc attttctgtt
    11281 ttggatcttt gaaaatattg actgctttca atccatttgc tgtagtgatc gacattttca
    11341 atgtttgaat atcttttgat acagtgattt ttaatttgaa tccttctttg ctttgcggcg
    11401 tggcatctaa tggtcggatc aattgataat tgcctccgtt tgtttctgta aatccattat
    11461 cgcgcaatgt atatcttttt gcatcaggat gcaaacgata gctaattggt gcgcccagta
    11521 ccgttgctgt tgtttcaaat gccatgattt tcacctcgat aaaattagtt tctctttatt
    11581 ataaaagttt atcctgattt ttactaggtt tttcagttaa gttccctaaa aaatgaaggc
    11641 gttctctcag acatctgttc atataagaat gacttcacta gttatttttt gacagcacga
    11701 actaattgat caaggaaata ctggatgtcg tcttcggtat ttcccaaacc aaagctgata
    11761 cggatggatt cttttagtat cggtgtatct tctccataca ttgcttctaa tacgtgtgaa
    11821 ggctcgatat ttcctgctgt acaagctgaa ccagtagaaa tagcgacccc attaagatca
    11881 agcttcatca gtagcaaatc atttgcttcg ccaattaagc gaagattcaa cacatgaggg
    11941 agtttattcg ttaaatcacc atttacttga taagggattt cgtttgcttc taatgtatca
    12001 agaatcaatt gctggaatcc tttatatttg ttgttacgtg cttcacgttc ttcagatgac
    12061 agcagttcaa ctgcttttgc cataccccag atccctgcta aattttctgt acctgcacgc
    12121 cgcttttctt cctgctcccc gcctaaaagc aatgcaggga tatttactcc gtctcgttta
    12181 tataagaaac cgacgccttt tggcccattg attttatgag cagagatact taataaatcg
    12241 attcctaatt cttctggatg gatcgtttgg tttccgtacg cttgtaccgc atctgtatgg
    12301 aaataagctg ggtgatccgc taaaagttca ccgatttctt tgattggcat caaatttccg
    12361 atttcattgt tcccgtacat cacagagacc aagatcgtat cttctcgtaa cgcttttttg
    12421 acctcttcga tcgacagatt ccctttttca tctacaggca gatatgtaac gtcaaacccc
    12481 tttgtctcta aatatttcat ggtattaaga acagcaggat gttcgatagc tgtagtgatt
    12541 agatgtctgc cttctttttg acgcgagaac gctgtttcta agatagctgt attatcccct
    12601 tctgttccac cactattaaa gatgatctcg tgaggttttg cttgcagact gtctgcaatg
    12661 atttgtcttg ctgtttccaa tttttcatgc gcgtggcgac caaatccatg tatgcttgaa
    12721 ggatttccaa acgtgtcttg catgattgcc gtcatcgctt caattacttg tggatgcatg
    12781 ggggtagttg ccgcatgatc cagataaata gttttcactt cattcatccc ttccaaatta
    12841 ttgctaggca cattctagca taaaatagcg aacaaaccaa agaagagctc atttttgtct
    12901 agaggacgtt tcatgggcat agaaaaaagg agctgtgaca aaagtcttgt cgcagctcct
    12961 tgaagctgct cacttgtgtc acaacttctt tccctctttt tttgtttatt cgaattcttt
    13021 ttcttccaga cggaataacg gactcatcgg tgtattttca tggatgcgtt tgaccgcttc
    13081 tcccattaat tctgaacatg taacgattgt taagttttct ggatgacgat tttcttctgt
    13141 gaaaacagaa tcagtgatac aaatatcttt gattggtgca ttgtctaaaa tacttttcgc
    13201 atgatcggac aataatccat gtgacgcaca ggcatatact tcttttgcgc cgttttcttt
    13261 taatacattt gctgctcgtg caagcgttgc tcctgtgttc aagatatcat ctaccatgat
    13321 acatgtcttt ccttgaacat caccgatcac ataaccaccc tcagttgaag catcatctgc
    13381 atgatctacg atggctaatg tgctgttcaa atattctgaa agactacgtg cacgctgaac
    13441 accgctgttt tttggcgaaa caactacgat gtcatctccc gtcagaccta attgacggta
    13501 ataatgagca aacaacggca tcgtaaataa attatctaca ggaatatcaa agaatccttg
    13561 tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt gcccctgctt cttcgatcaa
    13621 gttagcgatc aatttcgcag tgatcggttc atgaggtttc gccgtgcggt cttgcctagc
    13681 atacccatag taaggcaata cgacattgat cgttttcgca cttgctcgct tcattgcatc
    13741 gatcatgatc agtagttcca tatagtagtc attgacaggt gcattcgttg attgaacgat
    13801 atacacatga tcccctcgaa tactttcttc gatattgatg gaaatctcgc catcactaaa
    13861 ttgcttcacg acgcttttac ctaattctgt tccgaacact ttcgcgattt tttcagctaa
    13921 tggacggttg ccattcaaac taaaaatctt caacgtgtca tcctgatact tattactcat
    13981 gtagtcctcc ccaaaacttc tctattcttc gatagtttaa catatttttc caagattttc
    14041 tgttaatttc agcaaattct taaggaagtg aaactgttcc gttactccaa ctggcaggaa
    14101 tgactttatg ataatcgccc cagttgtcgt gtactttgta ataacgttct cctgtttcag
    14161 tttcaaaata agcgtacgct gtcacccaat gattgccata tgtactgcca agtactttca
    14221 aaataccaat catcacaggt ttgccttcac gtatacgttt tgtagctcgc tgccatgaac
    14281 ctagaagagt tgctcgtgca cgctcatgat tgccattctt ctttaaaaaa ctagaaatcc
    14341 ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg ttggatctgg ctacgcaatg
    14401 ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg aatctcattt ggaagcatcc
    14461 accccttacg atagtcttga taataggcaa ggagaactgc tgccgcgtaa gtaccacaaa
    14521 gatagcctga gggggtagcc catttcttat acctcaaaaa acgttcttct ggcaatccca
    14581 cccagcaatt tgcgagttcc tttcctgacc ttttttcttc gatcaaaacg ggaatatctt
    14641 cttttctgtt gatccatcta gataactcga ttggctcttc attgatcagc ttccattttt
    14701 tacaagaaag accctcttga taagtatatt ttgctggaga atattctacc ggatgtcctg
    14761 attgatcgat aatcacataa ctttgatctt caaaaaccag agctaaaaaa agcaatttac
    14821 tttttcttga ctgcagctgc tgagtgctgg ctaatttttt aattttttta tctactttga
    14881 aatataaagg tttatccact acttgattca gttgggatcg cctccttttt ttcattataa
    14941 gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa ttttcaattt tttatgttct
    15001 atttgttaat tccttcattt tgtaagataa tgggcacacg aaacaaaaaa ggagcgatcg
    15061 atgaatgaac aaagaacgat tgaaacaaga tttctatgaa gcagtcaatg aagaatggca
    15121 aaaaacagca aaaatccctg cagataaacc agctacaggc ggtttccaag atttagttga
    15181 cgggatcgac caacttttga tgggagaaac agacgatctg cttgcccatc cagaaaaagt
    15241 gtcttcagaa aaaatgaaac atttccttgc atattatcaa ctggcaaacg attatgaccg
    15301 aagaaatgag ttgcatgctc aaccacttca acctataatc gaaaaagttg aatcattgca
    15361 gtctttcgac gaattgaatg agcaatttcc agaatggctg ttggatacat taccattgcc
    15421 atttaatctg gatgtagatg cagatatgaa gaatgcgcaa acgaacgcct tctttgctta
    15481 tccgccttct ttattccttc cagataagac gtattatgca tcagaccatc ccaacggtgc
    15541 acaactaata ggcgttttct ttgatatggc tgttcagtta ttagagcttg ccggcaaaga
    15601 aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa tttgataaat tgattgctcc
    15661 tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa atgtataatc cgcaatcttt
    15721 tgatacattt attcaataca cagataaact ggacttgaaa aaacttgtca cgggtttgat
    15781 tgggacaact ccagataaag tgatcgtaac tgatccagtg tacttcgatc atttgaatga
    15841 catcctgaca gaagctcatt ttccgttatt caaaagctgg atgatcatta aaacagtacg
    15901 ttctcttagt ggttatctat cagaagaatt ccgccaagtc agcggaatct attctcgcgt
    15961 attgtctgga acagacgaag caatgcctca gaaaaaagca gcgtattacc ttgcctctgg
    16021 acaattcgat caagtagttg gcgattacta cggaaaaaaa tattttggcg aagctgctaa
    16081 aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt tataaaaaac gtctagaaga
    16141 aaatgactgg cttggggatg caacaaaaga aaaagccgtc ataaaattaa ataacttagg
    16201 tatccaagta ggctaccccg ataagatccc agcattattc gaccagttca aaacagtacc
    16261 tgcagatcag ggtggtactt tgctttcaaa tactcttgtt ttcagcaaac tcacattaaa
    16321 agatcgtttc agcaaatgga acaaaccagt ggatcgttca gaatgggaaa tgagtgctga
    16381 cacggtcaat gcttattatc atccatttcg gaatgtgatc gtctttccgg cagcgatcct
    16441 tcaagcacca ttttacagtc tagaacaatc aagctctgct aattatggtg gaatcggagc
    16501 tgttatcgct catgagattt cccatgcatt tgataataac ggcgctttat ttgacgaata
    16561 tggcaacttg aacaactggt ggacagaaga agatcttaca caatttcaaa acaaagcaca
    16621 agcaatgatc gaagaattcg atggtctgcc ttttgctgac ggaaaagtaa acggaaaatt
    16681 aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc tgtgcattgg aagcagcaaa
    16741 aacggaatca gatctttcta tcgaggaatt ttttgtcaat tgggcaacga tttggcgtac
    16801 aaaagcaaaa aaagaatacc aacaactttt actgcaaatc gatgtccatg cccctgctaa
    16861 actccgagca aacgtgcaac caaaaaacct tgacgaattc tatgaaacat ttggtatcac
    16921 ggaacaagac gctatgtatc tagcgccaga aaaaagagtg cgaatctggt aagaggttgt
    16981 gaaaaagccg cttagtttca agtagtaaga aaaattttgt gaaaatagct ttccacattt
    17041 ttgcataaat ttgacttact actgagaaac tggcttttga acaccgttta tcgagaggtt
    17101 gtgaaatcag cgtcctgacc tgagtattag agaaaaaaac ggaaaaatag ttcttcatat
    17161 tttgccgttt gttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaga
    17221 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aatcaaaagc agcaaggaga
    17281 acctcatcta taaaaagata gaaggaagtg agacatctat tggtctcatt tccttctatt
    17341 tttactttcc tcagtcaatt gttttacatc ataaaaggag aaattccact tatttttttc
    17401 gctgtttcat gacataaaca actacaccga ttaacaaaat tcctccagct aatgctagca
    17461 acgggttatt aaattctccc gtttttggga gtccttgagt gccatttttt tcactttctt
    17521 ttgctgtcct atccggatga gaaggttttc catttggttt tccatttggt tttccatttg
    17581 gtgattcatt tcctggattt tctctttctg gtttgtcatt tcccgggggc acatcggcag
    17641 tttctcgcac agtgatcgct ttttgctggg taacagattc tgtatgagca gaccattttt
    17701 ccccatcaaa tatttccgaa cgataagtga cttctagcgt atattctcct tttgaaggtg
    17761 ctgaaaaaat agcggtatga ttagaaaatt gagcacttga ctgtgtttca acgatttgga
    17821 tcttttctgg gaaataacgc atatcttcaa agacaggcgt tccttgattt ggtgtgaaag
    17881 ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt tccttctgca ttctccgcca
    17941 caccatttgc ttcttgtata ataatcggat tattttgttc atttggtttt gtctgatttg
    18001 gttcttgtac gattgcatat tctggatact ccgaagacgg tgaggtttct ccgtcaaaag
    18061 tagcacctac agatagtgga agaccatcta ctcttccctt ttctgtttga cgattctccg
    18121 gtttgatttg catcaatcca tggacatgga tgcttccatt cgcatagcga gtaacaggct
    18181 gctgcccttc ttgcgaatgt gtatttagag attcgatcca atcttttgat acggtatgtc
    18241 caagagtatt ttctgattgt ttctctcgtt cattccaata gtagttcaac gagtgataga
    18301 tttgatcttc gttttgattc aatgggcgga tctgctctct catctcaaga ttttctgttc
    18361 ggaaagataa gataccagaa gcatggaagt ctgtgtttcc tgccgaagag gtataaagag
    18421 ccacattata tgaaccgtta ttaaaacttg tactgctatt gacgataata tctgttccgc
    18481 tattggaatc gattcctttt gcaagatttt cgaaagacaa actattgatc aattcatgag
    18541 ggcccgataa agaggaatca cccattttga atccattacc gttcccttct ccttcaactc
    18601 ccggtaccca accgtttcga taagcaactg agtttttgat gactactttc ccgattgaac
    18661 ctgtttcatt tttagcaaaa agatcccaac catcatctgc attatgataa gcgatacaac
    18721 cgtcaaatac attcccttct cctattgtca gtttggccgc aaatccatcg gcatcttcaa
    18781 atcctggatc ggcattttca aaagatgtac agttcttgac taagttatgc gctggccatg
    18841 cttcgaaagg atcatttgag ctaccactga tttggattcc tgtatttcca ttccgataag
    18901 catggatctc ttcaatcaaa ttatggtttc cagaaatctg caatcctttt tgcatagcgg
    18961 cactatttgt aacgtcaaac ccacgtaaaa cccagtaatg actaaacagt gtcatcccat
    19021 ttccagttcc tttaaaatca agtacaggtc gcttgttttc tggatttttc tctgcaatca
    19081 attgaatcgg gttttctctt gtcccgttaa ctccttttgg aatcgtcaat cctctttcaa
    19141 aggaataagt tccaggagcc aggacgattg tctgcccagc atatgcgtat ctcaatgctt
    19201 gcgtcagaga taacggattt tgtctgcttc cgtttcctgt atctgaccct tccggtgtta
    19261 cataaactgt cgaatagtta ggtttacggt agtcaactgt atgcagaatc tcttttgttt
    19321 cataactagc catctctacg tattcttctg gcggatagtt tttatctggt gtaaaactga
    19381 aagtaaattc gttcgttcct tccatcagtt ttgtctgata atcaaattcc cgatttgcag
    19441 tgattgccaa gtcttttgcg ttctcaagta cctctcctgt tgcttgattt ttgattgtta
    19501 ataatccgtc agcatttgct ctaaaggaca tagtatggtc ttggtttcct gaatgattac
    19561 tagaggtcac agtgtaaatc ggatcaatca agcgagtaag tctttcttgc ccaggaggat
    19621 ctgtcgcagg atccgagtaa gcaacttcga ttccttctac cttgatcgtc atattccttg
    19681 ctgcagcaaa tcctgcataa ataaccgatt catctgaagc gtataatttt tcccagtcat
    19741 acatgatgtc agaagccatt tcttctcctg tttcaggatc gtaataatat gcctctaaac
    19801 cagtattcgt ttttttcatc tctacgtcca gtttagtaat cgagttcgtg gccggaaaca
    19861 gattcccatg accgtttccg aatatattat aagaacctgt ttctttttcc aagaaccctg
    19921 ctgaagtctc taaaggtgtt gtttccactg agacactccc aggagctggc gcagcttgcg
    19981 gatcttcaga tgatattcct gtgattgccc gtgtccctaa tccaagtcgc atcgtatatt
    20041 tgctgccgct cgtgttgacc acttcttgtc tatccgagtc ccagacatat tcgatccgac
    20101 tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc aaacaaatga tcttttggta
    20161 ctgcgtctct taccattaaa gcaaatcctt cttgggcatt cgtataggtc caagattcta
    20221 tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg gattgcttga taataatagg
    20281 tcattccatc tggtccgctt gactggaatt ttccgccgtt attcgtggaa gagagccgca
    20341 cgccgtcttc taatggttca atggcatacc tactagcact tgtgctttct ccgaaaacaa
    20401 cccctttcca ctcttcattt gcttcttcag attgcttttt tgtcttttca ttttctgatt
    20461 ctttcatcat aggatcattt ccttcttccg tatccatatc ttcactagtt cttggtactt
    20521 cctccattgt tgacatccct tcaatgttca cgtgtgcatt ttcttcgttc acagactgtt
    20581 gttcgttagc agcaacttca acgacagaaa ttaaaaccgg ggtactgagc ataaggagat
    20641 tcatcattag cgcactgtat tttatacgtt tttttaacaa gtgtattcct cccgtaacaa
    20701 attagaaagc gtttacttaa agtattacct aatttatttt tactgtcaat aaaaaacaaa
    20761 attataataa gtgtatttta taaaaagaaa aaatataact taagttgttg ataataaaga
    20821 gatttattaa cggaaaaaga ataagttttt ttaaaataac gtataaaaaa gagcataaaa
    20881 caaagtcgtt tgttttatgc tcttctttta ttattttgtg ctttttattt tatcaaatca
    20941 ctttgttttt ttataaaatt tctgcgccta gtgtggactc aaaatgtctc aatgcccatt
    21001 catgtccaac gggatcgaaa cttgccacgg aatctttgaa aatatggagt ttgtatccta
    21061 gattatacgc atcgactgct gtatgcaaca cacagatatc tgtacatacg ccggtcaaat
    21121 aaatatctgt gatctggcgt tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg
    21181 aataatgccg tttgtctatc caataaacat tttcctcttg ctcatagtct tggtataaac
    21241 tttttaaaga gccgtacaat tcccgtccac ccgttcctat cacattatgc ggaggaaata
    21301 agcggttctc cggatgaaag gaatcttttg gatcatgcgc atcaatggca aaaacgacaa
    21361 aatccttttg atcaataaac ttctttgtat gagcagtcag ctttttttca attacttgtc
    21421 ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg
    21481 agatcaatgc gttcatctta gtcctcctta tacgagatgt ttgacaaatt cgatcaccat
    21541 ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg
    21601 atctgctgtg tcgctcattg cacgtacgat caaaaatggg atattgaact gacgagctgt
    21661 ttgtccaaca gcggctcctt ccatttcgca agctaatgct tcagggaaat tcgttaagat
    21721 ttctttgatt ttatctggcg agtcgacaaa tgtatcacct gtaacgatca atccttcttt
    21781 tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc
    21841 ttcataatat agaggcattc ctggtaattg tcctgggttg tagccaaatc ctgttgcatc
    21901 tgcatcaaaa taagctactt tgtctgatat aacgatgtca cctacttgta agccttcacc
    21961 gattccgcca gctgaacctg tattgatcac catgttcacg ccgtattgtt ggatcaacag
    22021 acttgtggta atagatgcta agacttttcc tataccggaa cgtacgacga tcacttcgtg
    22081 gttacctaat gaacctgaaa taaataaagc gcctgcgcgt tcccatgata atggttcgct
    22141 taggttctct ctcaaaattt ttacttcttc ttccattgcg ccgataatac cgattttcat
    22201 ctttttaatt ccttctttct atataaatgc gattgctaaa aaaaccacac ataacattag
    22261 gataacaata ataagagatt tcatcaaaaa agagttccat ttggtcgtct tttcccgttc
    22321 gctgatcctt gttttcgtga ttggtttatt ctttttgctt tctttacgat aaaagctggc
    22381 aatctttttt tcttcttgct gataagctgt ttctgctttt cgctgttttt ttaatgactc
    22441 gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc
    22501 cataagccga tccctctact ttcctttggt caatagttcc cagtattgaa tcgcataaat
    22561 cgtctttgca tcacaaatca actgatcttt catcgcttgt tgcgcctctt caagagttag
    22621 atgatacaac tccagtactt cgtcttcatc ttgtgctaaa ggattctcga ccttctctac
    22681 cccttgtgca tgataaatat gaaggacttc atttgcaaaa cctggtgaaa gatacatcga
    22741 agtaagatgg ctcagcgact tcgcacgata gccagtttct tcttctaatt ctctagctgc
    22801 tgtcatttcg ggattttgtc cttctcctgg atcgattttt ccagctggaa tctccaaaat
    22861 cactttttct aaaggttttc gaaattgttt gacaagaagc agacgatctt gttcgtcaaa
    22921 agcaatgatc ccgacaccgc caggatgaaa taccagttct ctcttcgaag ttcctccatc
    22981 tggcaaacga acttcgtcta cagcaacatc aataattttt ccgctataga tttctttgcg
    23041 actgattgtt ttttcttcaa attgctcatt gttcagcata tcttctcctg ctttctttgt
    23101 aatcataact gctttttttt catttttcaa tttttctcaa aaactcctta ttagtttacc
    23161 atagataaac cttagatttt ctctaaatat agaaaatcct tctttagtcc gatactcttt
    23221 ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa cgaaaagaat tcaatactca
    23281 acgataaatg acatggaggg tttattatga taaaacgaaa ttggccgtgg cttctagcat
    23341 tggtcttgct atttctcttt gtccgaaaca atagtttttc ttttgttcta ggacttttat
    23401 tgataggtgt agttttagtt ttgtggggac tctttggttc gcgcaggaaa aagggaaaac
    23461 aagaagaaat tcctgcactg actgacgaac ttgaaactca ctatgaaaaa agcggtatga
    23521 cagcgaatga aatttcattt tttcgacaaa caatgaatca aacaaaaaat gagatcaatc
    23581 aattgcaaat gaatatgcag cagacagcca aacttaaagc aatcgatctc cgccatgatc
    23641 cagtcaaagc agcgaaagct ttattcaaag aattggtgaa agaaccaaac cgactgcatg
    23701 aagcaagtca gtttctttat acgcatctgc cgaatctagt tgatttgaca aataagtata
    23761 atgagatcaa tgaccatgag atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg
    23821 cgcagatcat cgaccagctg tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg
    23881 aggatctaga tgatatcgac gtagagatat ctgttgcgaa acagagctta aagcgtgata
    23941 ataaatatga accagaacaa aaggattaac tcttttgttc ataaaagaag actcggaaca
    24001 ttcagatgat gtctggctgt ttcgagtact ttttctaaag tagagacatt catgtaagaa
    24061 tcgagaacag attcaacaag gaggaatttt ttatggatca taaaccgact gaaacaaaag
    24121 atgttacacc agttaacgat acacttgaag atttattgaa caacccgttt tcaactccaa
    24181 cagatacgct gaccacttca caacaagcgg agattgatca gctccaagag caacagacag
    24241 ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga acaagctaaa cagctagcag
    24301 caaaaatcga tgctaatgat gcacagtctg tcatcagcta cggatcggct gcccaagcaa
    24361 aattaagtga attctcacaa tcgatgttga atcatgtgca agcacaagat attggtcctg
    24421 taggagattc cttaactgaa ctgatgtatc gtctccaaga agccaatcct gacgaactgc
    24481 gtgccggaga agggaacatc ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg
    24541 aagtgacagc aaaatatcaa aagattggtg cacaaattga caagatttca gtgaaattag
    24601 ataaagaaaa agacggtctg ctaaaagata atctgatgtt agaacagctt taccagaaaa
    24661 acaaagacta ctttgatgca ctgaatattt atatcgctgc tggagaattg aaaatggaag
    24721 aacttcaaac aacgatcatt ccagaagcga tgaaaagagc agaagaaact ggcgatcaga
    24781 tggatgttca gattgccaat gattacacgc aattcctaga tcgtctggat aaacgtacgc
    24841 atgatcttcg cttagctaga cagatcacga tccagcaagc accacaaatc cgtttgatcc
    24901 aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc tatcgctaca gccattccgc
    24961 tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg tcaaaaagat gcagtaactg
    25021 ctcaacgcca agtctctgaa acaacaaacg acttattgaa gaaaaattca gaaatgctga
    25081 aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc
    25141 ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga gacattgcgt atccaaaaag
    25201 aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg acacatggaa gaagatctga
    25261 aacaaaaact gttggattta acccaataga tcacctttcg cttgttacta aaacaaacgc
    25321 ccaacaacag tttattacaa ctgttgatgg gcgtttttct tatctttctt ctaacttctc
    25381 cattggagtc tatttctcat tcatcttgct gtgtccatag ccatagccaa aataaatgat
    25441 cagtccaata accattacga taccgaacac gatccatgtc acagtttgca gacgaagcat
    25501 caatacaata caagtcaaga tggagacgat tggcaatagc ggaacgaatg gcactttgaa
    25561 ttctccagct tttggtttgc caaacatttt tctcaacttc agtaagccta gactaacaag
    25621 catcaaatag gcgagcgcca tgatattcgt tagttccgct aatacattca atgggaaaaa
    25681 tccggcaaag aatacagctg ccacaccagc ggcataagtc gcttttttcg gtgtacgatg
    25741 cttttgatcg atttctgtca taaacttagg aagtaagcca tccttgctga cagcaaacag
    25801 taaacgagca agtgaataca tcatcgagat cgttaccgtc agtagcgtta aaattgcccc
    25861 tacagcgatc accgcgccca ctgttccatg tcctacatac ctcattgcaa aagccactgg
    25921 gtcattgact cctagttcag tatacggaac gattcctgtc aagatcagcg tcacgatgat
    25981 gtaaaggaca gtagcaatca gtatcgaacc aatgattcct cttggcacat ctttttgcgg
    26041 gtttttgact tcctcggctg ccattgcaac ggcatcaaat cccaagaaag caaaaaacac
    26101 aagagctgca ccatctagca caccggaaaa accaaaaggc atgaatggct gccagttatc
    26161 aggtttaacg aaaaatattc ctacaatgat aaacaacgcg atgataccaa atttgacata
    26221 taccatggca ttattcaaac gtaatgcttt cttggcttca agcgacacga tgtaagtgac
    26281 gaatatcact acgagcaccg caatcaagtc aatgtatgta ccattttccg gattgtaccc
    26341 gccagttaat gcttgtggaa gttcggcccc taaacttttc aaaaaacctt gcatatagcc
    26401 agaccatccg gaagcaacag aggaaaccgc tagtaaaaat tccccgatca acaaccaccc
    26461 tgtcagccag gcagcaaatt caccaaatac aacatacaga taggcatatg gcccaccaat
    26521 cactggcact cgcgaagcaa attctgcgaa acttagtcca gacaaaatga taacgattgc
    26581 agctaagaca aatgaaagtg acagtgctgg accagcattt tgattggccg caacccctgt
    26641 caccacaaat attcccgtac cgatgatcgc accaattcca agcatgatca aatcagacgt
    26701 ttttagttct tttttcatct cactcgtatg attgagattg atctctttct tacgaaacaa
    26761 atccattgaa gttcctcccc attttaggtt ggaaaacagc gattaaactg ttttcatata
    26821 ccctaaaagg ataccaccta aaatgactaa aaggcaacca acaataacat aaatgagctc
    26881 ttttttcgtt tttctttcgc caaggatgaa aatcccacct aaagtagaga taatgatccc
    26941 catttgtgaa agtgagaagc caacagctaa accaagtgat ttgactgtta gaagcatgca
    27001 gatgtttcct aagccccata ataatccaca gatcatgttt ttccacacaa actgatcgac
    27061 tttaacttta cggaaagcaa agaagcttgc gcctaagatc attccgatac tttgaggtaa
    27121 gataattgac atcgcatcca aattcgccca gttgacgatg atggtatata caccataacc
    27181 aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa tcaagcattt tattatctgt
    27241 atctattttt ccttcgtcat cttgtcgggc agtcaaatac gcaccgctta caagaagagc
    27301 taaagcaata ataccgtata cataatcttt cgtttgtgtc cattcatgga agaaaacggc
    27361 tcccgcaatc gtattcaaaa ttaattgaaa accagtagac aatggtagcc ctacagaaac
    27421 acccatgtac ttcattccat ggaactgtcc attttgtcca acactccaag ctaagccgga
    27481 taaaaatccg atcaagaaaa tccaaggggt gattacagga ctaacaacga aaaagacaac
    27541 taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt tgttgattgg catcgccacc
    27601 aattttacca cttactaaac caatactacc ccatgccaac atagggacta atgctattaa
    27661 aatttccata accaatctcc ttttatttca catgataaga aacttatcag cgaaaacgtt
    27721 aacaacacaa gcactttttt tcgtttctaa cgattttcta acgtttttca ttataaaaat
    27781 ttaagattgg gaaaaataaa gtcattgttg tcccttttcc ttcagttgat tcagccgtca
    27841 aatggatacc taatttttcg gccagatttt ttgctaaata aagtcctaat cctgttgaat
    27901 gtgttttgct aagtcgacca tttctcccag taaatccctt atcaaagatc cgtttcaagt
    27961 cttccgctgg gataccgatc cctgaatctt taactgaaag gctgactcct tgcgcttcct
    28021 tttctatgct cacaatgatg tttccgtgat ccggcgtata tttgatggca ttactaagca
    28081 attggttgaa gataaaagcg atccatttag catcggtcaa aacagtatga tcctcaccaa
    28141 cgatctcgta gcgaatattt ttttggataa aataatttgc ctgactgcgt atcacaggct
    28201 gaatgattcc ttttagtcca tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc
    28261 ttgcataata caaaacttgt tctacgtatt catcgatttt tgataattca ttttctagta
    28321 atgtatactt ttgatcgtca atatcgaact cgatcgaacg aactagcaat ttagaagcgg
    28381 aaagtggcac tttgatttca tggacccatg agtcaatata atctttttgg tcttgttgat
    28441 tactgattgc tgattgcatt acttcttggt gttcacggat cagctgattg atatattctt
    28501 ctaccagttt ttcttcttct gtcctcccac cactcaaata attttgcaaa ggggaagttt
    28561 tttgtatgtc ggctaatttt ccccaccatc ttctcttgct caagtaacca cccagcagat
    28621 aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc aattgtgctc aaatcaactt
    28681 tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc aataaaaaac agccatccca
    28741 agatcaatgt ccactgatct ttcaaatatt taaaaaaatt catcttaacc gctcatcctt
    28801 tcagggaacg atatatccct gtcctacttt tgtttcgata tatccttgga tacctgcctg
    28861 ttcgattttt cggcgtaacc gattgatgtt gactgtcaat gtattgtcat ctacaaatcg
    28921 ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt aagatctttc cattgtgctt
    28981 catcaaaata aataatagac gatattcatt tttgctcaaa tcaatgatct ctccgttgat
    29041 ttccatactt ccgttgtcaa cattcaacgt aatgccattg tggctcatca tttcactaga
    29101 taattctgtg tagttgtaag aacggcgaag taatgcattg atttttgcaa tcagtacatc
    29161 gatttggaaa tgttttgtca caaaatcatc tgcccccatg ttcatagcca tgatcatatc
    29221 catattcgta ttcctgctgg agataaaaat gatcggtact ttcgatactt cacgtatttt
    29281 ttgacaccaa taatagccat ccaaaacggg aagattaata tctagtaata caagctgtgg
    29341 ttcttctctt tcaaagtctg agaacacttg attgaaatcg gtcgttccaa aggtttcaaa
    29401 ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac
    29461 catgattttt gccataaaaa atccctccat ctttcttctt gctactacaa tatcaaagaa
    29521 gcccttgtga aacaagttgg cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa
    29581 ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc agcttaaatt tattatgtta
    29641 ttcttaataa ttggtctatt atctgttatt tttctttcgt tgtttttgtc ttttaaattt
    29701 tcgataacac caataaccga aaagcgttag cactagcaat atacctagaa ggagtataag
    29761 taatcgataa agatggtatt tttttgtctg ttctatcttt gaagagactt cttctgtaaa
    29821 gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt
    29881 gataagtgtg actagatcct gcttttctct aattgctaat gtatttgttt ttgttggaag
    29941 gacaacaatt ttctcaacga cttcataagc gagcatccga ccatacactt caagatagaa
    30001 tcggtcatct tgctccattt cttcaagatc cgtaaagagt tttttctcag caataccgct
    30061 atgggcggta atcacggaat gtgtactctc tcctccagtt ggaaaagagg tgccttgcag
    30121 gactgtcgct cctctatcta acaaaagatc attcgtttca tcaaataaag gcaagctaac
    30181 attgattttc ggaatataga tggctccgat catatgttgt tcgtaatatt cttttcctgg
    30241 attttggaca tttctaaccg cttgctcaaa aggatctttg acttgtccca ttcctgggat
    30301 tactgatgta tgagcaagcg tctgattttt cttttcatgc actgctaatt gttgctcatg
    30361 tttttcttct ttatcgcgtt caagctgctt ttgataattc tcgatccttc tttgatccaa
    30421 ataattgctg agagcatctg ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa
    30481 catcactgcc ataaataatt gtaataaaag actgatttgg gtttgaggtc tattacctat
    30541 tttctttttc attttcttca ccttcttatt taaaaaaact gcagcaacct ttataaaacc
    30601 gattgctgca gcttattttt gttgcttata cttcagactt cattttagat ttacggtacc
    30661 agctgtacgc tccaatcatc aaacttattc cgattagtaa gaatgccaag agcccgttcc
    30721 caccagtagc aggaagtgac ccgcgtttca tattcggtac tctttctggc cctggatttt
    30781 ctactcctac gatctgaatt tcttcattat agcttccata agagatgata aattcagtaa
    30841 aggctgcctc acctgttgga agtacataac cttctggcgc catggtctct ttcatttgat
    30901 aggttccata atctaaccct tgaacctcaa agtatccatt tccatctgcg acaaattctg
    30961 ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc tgattcataa acagctaaag
    31021 gcgactcccc tttataaaat attgcgtatt cagaacggtc ttcattccac aattcgaatc
    31081 ttgcatcttt aagcaattca ctgcttgatg catcatattt ttcaaacttt cttccacctg
    31141 ttgtgacttt ctctggcggc tctactcctt cttcataatc aaattcatca tttcgtccga
    31201 tttcaataac cgctgtgttg ttatggaaat catccgcttc tagttctgtg gaaaccttca
    31261 aattatacgt gatcgttaaa tctcctccac gtgcatctgc taatctacct aaagtatcta
    31321 ctttggctac tccattttct tctgtcaaaa tcgtcacgac aaacccgttg cttactactt
    31381 ctactatata atcttgtcct tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct
    31441 gatcataata agttagacca actgtaggcg tatctgtgat tttgtaattt ttgataacag
    31501 cgcttccgtt ttcaaggaca gaatcgatga aataaggaat aggtgctgtg atcgtgtaag
    31561 aagccgtttt tcctctttct agatcaatat aagaaatcgt ttcttgttct ccagcttcat
    31621 taataatcgt tacttgtcta aggtcgcttt cctctacatt catctgttta tctgcttctc
    31681 tgatttcgtt tttcggatac aaatgcacat ctgtattgta tgtgtctttc catgtagaac
    31741 catcccacac gccatccacc atatcaggca tcatcactgg catcataaca accattggag
    31801 acgcgattct ggaaatatga gctggcgaat aagtttctaa gaaaagatag actttatctc
    31861 tagaagaagg tgcttcttcc gtcacttgga cggtagagaa taccgcttct ccagcttcat
    31921 tcgttgtttg tttgtcaata cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc
    31981 gtttttgaat ccattcaatc gcttcggcag aattaagacc gtcttctcgt tccggtgtta
    32041 aaggattatc tcgaatcaaa tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga
    32101 ctcctggaat attttcttca ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt
    32161 ccggaacaga tgagaaacct tttttgtgta atgtaatcgt cacttcactt ggtttttgtg
    32221 cgacttcttc ggctttgact agttttccgt tcccgaaaat ccctattccc gcagtaacga
    32281 gtaacagtac actcattccc gtgacaatca tttttttatt catttttttc tccccgttct
    32341 ttttttatta ataaaacagc acctaacaat aaaagaattc ctagtaaaga aatcaacgtt
    32401 cttgcttcat tcgtttgcgg gaatacggac cattttcctg attgacctgg attgcttgga
    32461 ccactcggct ctttcggttt gtccgttgtt tcttttacgg tctcgttata aacacgtggt
    32521 gttgcggatt cataggcaga gactggaact ttcccggatt ctaattcagc catctcctgt
    32581 ccgttaacta ctacatattg tggttggcct tttgcatcca cccaaaattc agggatgatg
    32641 acctcgattc tcttacttgc ttcatccatc tcgtaacctt ccacaccttt taattcttca
    32701 aaataatagg tgccagaagg caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc
    32761 gaaatgaatt tgcttacatt tttgtcattc aaaggatcat tgtctgctgg tttgatccat
    32821 tgatttttca agtcattagc aggagccata tctaaataat atttcccccc ttctatcatc
    32881 tgatatagag caaaaacagc accttctaat ggttttcctt tttcagttgt tcctctttga
    32941 cgtccatact tgaagaagta tggatctctt agataaccga catttttagg atagatatga
    33001 atctcttgca gttcctcggt tgattctgtc gggtgataaa ttggcaaaat agcagcaatt
    33061 gggatagctg tctgatcgat atcaacatcc aatccaactt ctggatcaat cgattcttcg
    33121 aaaatcaaat aaactgcatc ccgatcttgg tttttcttag gtgctttgat acgtgcaatc
    33181 ccgtctccta atccgccaac cgtatctttc ccagttgtta ccgaagtccc tatttggaca
    33241 agcctttctt ctgtgattag ctgacggata ttgtttctgt tcgtttcagc gatttgctgg
    33301 acgaattctt taggagtcat gttttcagca gctttttttt catgataata atcggtcatg
    33361 tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct gtgaaatgat atctgctgtt
    33421 tcccctgctt cctcagagat agccaagcca tcattttcat ggtattcaaa ttgatcgtta
    33481 taatcgatat ctcgaatcat ccgtttatgc aacacgaatt ccacgacatc ttcccctgat
    33541 tcttctgccg acatcgcatg tggaagaagg actgctgcaa gcggtagtaa aacaagtaat
    33601 tgaagcatca aacacaacag ctttttcatt accttgctcc ctccttttta gattgtctga
    33661 caaacaaacc ataggctgct cctgcaagcg ccatgaagaa tgcagcaagc aggatataga
    33721 ataatcgtcc ggatcctcct gtagcaggca acggattttc aggatcgttc ccgacactaa
    33781 gctgtaatct gattcgattt gtctccaaaa gttcatattc taactcttgc tgtagatcag
    33841 gcgtctctgc ttcttcgttt ggataatacg aaatctcaac ttttagtgta cccgcttctt
    33901 ttcctggaac tacccgatca ttttctatgt caggttcttc tcgataacta atttctaaaa
    33961 taaagtaacc tggaagtttt ctatagctgt caggtgactt cacttccttg atccgataga
    34021 ccccttccaa caagtctgaa gcattgaata gggaagaatc gtttggatct ggtgccaagc
    34081 ctccctcgat gatttcatac tctcctgcac tattttgttt ctcaattgaa aattctgcgc
    34141 cttcaagacg tcggctattc atactgtcaa ttttcaaaag ttccaaatcg attggcgcta
    34201 gttcatcttc taaggttact tgtagtacac catcgatgat ttcatagcct tccggcaagg
    34261 gagcagtttc gtcttcgatg accgtatctt caatgataaa cttaccttct tcattcagtg
    34321 caaactggaa cacttgatca gatagccgat acccatttgg tgcgacagat tccgagacct
    34381 catattcacc aatagacaga tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta
    34441 ctcctacggc acgagaatag aagtatccga tcccaggcaa acgtttcgat tcttctggtt
    34501 ctaacggatt accagtgtat gctcgataca gcgggaagga agaatccccc actttcctga
    34561 tatcgaaacc tgcaccatct aatgtatggc cttcatggtc taattttcta actcggatct
    34621 cccgataatc aaacgtattg taagcagtga atgctaccca taaacgatcc tcttcatctg
    34681 ttgtatacgt gagatattgc caattttctt cacctgtttg cttgagttgg atagtcccta
    34741 tagcattatc gtaaagtcgc aagatccatg tgtcattttc atcaggttct ttgaaacctt
    34801 ctgggttctg gctctcaatg attttgtatt ctgcatagtt ggtagtttct tcactatcct
    34861 tataaacaaa tgaatctggc tctccgattg gatgaataac tttctcacca tccacgatta
    34921 catatttccc gtcttcatct actgaataga acgtgagtct ccctttctct tcctctactt
    34981 cgttcacacc agaaagccct ttcgctactg gatatccgat ttccagtccg ttaccatctg
    35041 tttcataaag ttcaaactct gcgccattga ttggcatatt actgccttca attagtttat
    35101 tgatattcat gtggattggc ttgaattcat ttcgcatttc cagtttgaca tacaactcat
    35161 catactctgt gccttctatg ttaggctctt gtacaacaga aagcttgtga tattctcctt
    35221 cataatagga attcggatct ttaccttccg gtccgccgac tctcgaacca gatgtatatt
    35281 catctacaag ctcgtagtga cctaacatct catcttcgtt ggctgcatat tttttgattt
    35341 ggaattgata cgtctcatct actaactgat aacgtggtgg tccagcgatc tctctgatcc
    35401 aaaatatgtc gctgactgct ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga
    35461 tcgctattcc gtccgtggta gttttacttg tttcgattgg ttcggcttcc ccactctctg
    35521 gattttggtc atataatgca aattcgactc cagccaacgg ctcgccattt tgacccttct
    35581 tgctgacttg gaaattacgg cctttatgtt cgtaacgaat ggaagaagat gggaaataca
    35641 tccgtccagt agtgatatca ttctcataat cctccaggtt ctgaatatag gccatattgt
    35701 tcactgtgca aaaatttccg tcttgagctc ccgcatcaag ttttacttgg tacttgatcc
    35761 tgaccatttc cccttcacct aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc
    35821 cgacatacgt tgtcggagtc gccactactt ctggtggggc ttgtccatga cgttcttcat
    35881 cccatatttc tggctcttgg tacttcatgc cgttttctcc tggatctaga tggtaaaact
    35941 gaatatctgc cgatctgcca gctccaaatg gtgagacatt aaaaccagtt tcatcataaa
    36001 gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat atcctccaag gctgtaacaa
    36061 tgtcattctt gttgttcgca ttgtaatatc gcggtgttac gccatcttct tctaaatcag
    36121 caatattttt caatacattt cgtccaatag catctagtcg ttgtctcccg ctaacgtttc
    36181 catcgattcc taaaccaatg gagaagatac ttggcgggtt ctcttgatac ttgtttttca
    36241 gccaatgatg ataagcaact gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc
    36301 cattcgtatt gttattagaa gaaccatcac caacccagtg agtcgcttta ttatctcctt
    36361 cttttacctc tccataacga tagtgtacat ttacttcatc ttctggacgg ttaaagtcag
    36421 atgcataggt aactggatga gtaaaccctg cattagaagt attcccagaa aactcctcaa
    36481 aatttctgaa caaaacgtca ttatcttcag caatcttatc ttccatcaca gtccagttgc
    36541 tccaagctcc attagtgctc gtacgataac ttgactgaat cggtgcataa ctgaaggtcg
    36601 gtgtcccatc tcccacaacg attaggattt tttctggatt tctattttct ccgccattgt
    36661 ctttatacaa tgtttcatag ccatttttaa gccctagtgt aagcggagtt cctccgattg
    36721 gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg attgatatca tttgtcaatg
    36781 gaaagatgtc cgaactgatt tgctcatggt tattgatagc tgtactatta tggtaaaaat
    36841 tcaccatacc gattcgaata tccagactcg ggtcagagag cagatcttta ctcatttcgt
    36901 ttactgcctc aatcaacgca gcatttttag tttgactatt ggtcccagcg gttaattcac
    36961 tcatactcgc tgacttatct agaacaaaaa cgatatcgat tggactgatt tcctttttct
    37021 cgcccccgat gacatctaga tagacattgt aaagggttgt tgcatcttca ggatgtagat
    37081 cagatgctgt gctgcttggc agaacaggtt ctacccattt tttgatgtac gccccgttat
    37141 aatccaagta actgttttca aaattccgtt catttcccca aagctgaacg gtttgagctg
    37201 gaacgtttct atcttcttcg cctgcagttg atccattatt agtagcatag tcgtaatttc
    37261 gccagttcgc tcccccgttt gtataatcac tatcatcgat caagttctct ccgtcatatg
    37321 gcgagccttt gtctccttga tagcgttcat tgctttgtgt ccaatttcct aacacttttg
    37381 tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc gttttcaact tctccgctag
    37441 gatagatata ttcatagggg tcttgcgtag ctgttggccc aagacgctcc aaaataccgt
    37501 tgaataactg gcgttgaatg cgctggagtg cttgaccgct gggtacgatt ggttcgtcca
    37561 gcttttccat ctcattttct tcgctacgtt gaatttcagc ggaatcttct gtatcagttt
    37621 cattttcttg taattcttgg ttatctattc tttcatcaac caccacttga agaggtagtt
    37681 acccttcgtt cacatcgggg atcttttctg tttcaaaaat caatgtgccg gtttctgctt
    37741 cttttgaata aacttttccg acataccatt cttgaccatc gatcgtctcg acttttaggt
    37801 cttctccatc ttcatcatag gaggatagac ctgttccacg aacgtttttt acggtaccaa
    37861 tcccggcggc tgccgcatcg attgctaaac gtattctacc ttcattggca ctttcctttt
    37921 tttcaaaagc cagatgccat tcaagggttt cttctttttc aatatacttc ccttcaattt
    37981 ttgcatagtc ctcatctaag aatacctcat cctcctttgt ttctgttgac tcagcagcta
    38041 catccagggt cgtcatatga tagactgact ggaaatatgg tccaaatagc aaactgacag
    38101 ttactaactg caaaagcttc aattttaacc ctttcacatc cttatactcc tttcaaaaat
    38161 atttgtcttc tttcacaaca atcaacaaaa caatgcccat ctaattataa tttaatttaa
    38221 ttttaatttt aaatcaaatg atatcctttt tagttaaaaa caccaattat acaacattta
    38281 ttattaaaat taaattataa aattttataa cgttctcatt taacaaaact taagttatta
    38341 agacaaatga ataaacaact acgctttcct cgaaacaaaa aaataaagca caaatgcgca
    38401 tttacgcact catgctttat tcgtacaatt aattcagata acggcagcgc ataggatgcc
    38461 aataacactt cctaaaatag ctcctcctaa aatgtcagta ggataatgta aaagtaaaaa
    38521 aatcctcgaa taagcgatca aacaagcaaa taaaaaggct aatattcctg caactggact
    38581 taattcgaac aacgcagcta ctgataaaaa ggctagcgct gtatgtcctg aaggaaaaga
    38641 agaagtcttc ggtttacttg tgtaaaggac aagccgacga tttttttcat aaggtctttt
    38701 ccgtcttgtc gtttttttga taaaaagcaa accaacaaaa aaatagatca aactgccgat
    38761 aagaatggct agaccatatt ctctagtatc aggtatcaag actaaaacag cagcaaggag
    38821 caaccaaata aaaccaccat tagagatatt actgataaat ttcaaaaaat tgatttttcg
    38881 actatccgtt ttccgttgct tggcgaactt gttgataata ctatcatcga ttttagcaat
    38941 caaacgcaac atgttattcc tcctttttaa gaaccttttc ttgcgtacga tggataaaaa
    39001 gcaggacttg aaaataaaac aagaaactga aacctaataa agcaaaatag attggtcctg
    39061 caaaccagaa tgcgacaaga aggatcaacg tgcctgccaa atagaaaagc gcgcttttga
    39121 aatcattaaa aaacaagaaa aatgcagtaa tccaagaagc ttctttttgt tccagttgaa
    39181 gcaagatttt gtaactaaag agaagcgcgc ttaatagaag caaaaacaac gtagtataca
    39241 tcaatgtata gccaattccc ccaccccaat agcggaaaat ctgataatcg atcaatagaa
    39301 gaagaaaata aacacttgct aaactatctt gctttccata aagagagaag ttctcacgaa
    39361 actttttcca gaatagtgaa ccgagctttt tctcttcatt ttttttgtaa tgataaatca
    39421 tatacagaac tgttcgactt gcagttccta atgtgaaaac aggcaagacg cacaggaacc
    39481 atagtagctg taaatggata agacgtggaa tccattcaat gatttctaag aaataatcat
    39541 tggctttttt accaatcgat cgattcatca tccttttgaa cctcctgtca aatccatccc
    39601 ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc gtcgggatca agacaagtgt
    39661 tgctcctgcc atcagataat tccattgtgt cgttgcttgg ttctgaaaaa cttgcaagcc
    39721 aatctgtaac gtgtattttt cttgatcttg gatatataac agaggaccta agaaatcatt
    39781 ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag gcaggtttcg tcaatggaag
    39841 catcaaatga ctccaaatat acaaatgatt cgctccgtcg atttcagcag cttcgatcaa
    39901 ttcattattg atcgataagt aaaattgacg catcagaaat atattgaacg cattgccgaa
    39961 gaacgatgga acgatcaggg gcaaataagt acctacccag ccgatcttgg agaataatac
    40021 atattgaggg atcatcgtta caaaccccgg gatcatcatc gtagaaagaa ccaaagcaaa
    40081 catcagcttt ttcccaggaa aatcaagctt cgcaaatcca taagcaataa aagaatttga
    40141 aaggacatta ccgatcacta ctagcacagt gatgaataat gtatttcttg catagcgcca
    40201 aaaaggaaag gcggcaatcg tatccagata gttttcccat acgatttttt ctgggaaaaa
    40261 ggtcggagga taacgaacga tttcttccat tggtttcaat gaagtaaaca ccatccaaag
    40321 caatggaatg atcaaaatga ttcctattac tgtcatgagg acataactta gtattttttt
    40381 tgtttgccga ttcacactgg tctttttgaa ataatccatc atttgccgtc acctccagaa
    40441 taatagaccc acttaggtgc aagcttcaaa ttgacaaacg tcagaaccaa cacgatcaga
    40501 aacaggatca ttgacatagc catcgcataa cccatatcaa aagctacgaa cgccttgttc
    40561 cacatatgca gattataaaa aagcaaagaa tttgcaggtc cgcctgttcc atttttcgtc
    40621 atgacataag cttcttgaaa aatttggaaa gaaccgatcg tagaggtgat cacatcgtaa
    40681 aaaataatag gagtgattaa tggcaaagta atacttttga actttcccca aacgcctgct
    40741 ccatcgattt ctgctgattc atataaagat ctaggaacat tttgtaatgt agctaagtaa
    40801 agtagcattg ctcctccaga actccatatt ttcatcaaaa tcaacgcagg tttcgtccat
    40861 tgtggatcaa acagccaagc tggtccaggg atatggaacc agcccagaaa tgtgttgatc
    40921 aatcctgcag atggagaaag cagctgcatc cataagatgt agactgctac tcctgataag
    40981 actgccggta aatagaaagc tgtacggaat acactgattc ctttgatttt ttgattgagt
    41041 actgtggcta aaaacacact gaaaatcgtc gtcagcggta cattgaagat gacgaaataa
    41101 acggtgttgt ataacgattt ccaaaataaa tcatcgtgaa cgaacattct tttgaaattt
    41161 gctagaccaa tgaaattcat cttggatgtc aaattataat cggtgaaact accaataact
    41221 gaaaaaagca taggccctag cataaatacc aagaacccga taataaaagg cgagataaat
    41281 aaataggccc atcttgcttc ttttttcttt cggatagata aacgcttcaa attttcttgc
    41341 ctcctctgta cctagacagt caaaaatgga ttattgattt tgcttgacta agttttctac
    41401 tgctttttgt gcatctgcca atccttcttt tggtgatttt gttcctaaaa gaatctggtc
    41461 aatctgttca ttcactaatg tcgtgtaatc cggagcatct aaaggaactg gtgtgatcac
    41521 cgtattttta aagttttcgt ccgccatttg atagatcatt tttcctttat ccgttaggtt
    41581 gtcattattc actaaattct cattggctgt cttgctcgcc atgatatcaa aacttttttc
    41641 gccgaatttt tcttgtactt ctggagaaga aagatatttg atgaattcat aagaggcctc
    41701 aggatctttt gctccgtatg gtacttccaa gacgaatccg ccaccccacg accaatggcc
    41761 tgaaccttct tctttttctg ggagctgcat cacgccaaaa tcaaaatcat ccggtgcatt
    41821 ttccatcaaa ctagagtaat aattgatatt ttgggcacgc atggctacta atccggaaat
    41881 aaatggatca gatacaccag acccaaattc ggcttctaat ttattgatcg tatttttccc
    41941 ataataatct tgccagtctt ggatccactc caaggcttcc actttatttt tagtatcaat
    42001 cttgactttt tcatctttgt caaaccaact agtcccgtta tctgcgttta gcgcccatac
    42061 atcagcccct aaattccata atggataaaa accgatgcgt gtaaattctt ttccttcttt
    42121 tttatctagt ttacgtgctg tttcttctaa ttcatcccaa gttgtcggta gatcttgttc
    42181 actgattcca gcttctttaa ataacttttt attataaaaa atgacttgtg tatctgtatt
    42241 gaatgggatc gcataaggat caccttcata ttctactgta tcccaaagct gcggataaaa
    42301 atccttagaa gtgtcttttt ctacatattt ggagagatta gttgcttgct gtgcttctgc
    42361 tctttgggca acggaattta tgtcctgtac aataacatcg ggtgcatttc cagctgttat
    42421 tgcagataaa gatttagtcc agatgtcacc ccatggctga tacttataat ttacatggat
    42481 ctcgttttgt gattgattga aatcctcaat gatttcttcg atagcttctt ttcgtgcacc
    42541 ggatccccaa aaggaccaga aatcaatatt ttttcttcca tcacttgttt tttcagaaga
    42601 atttgctgca cttgaactgg catcgcttgc attacttgat ccgcatcctc ctaataaaaa
    42661 caatgctgaa cttgccagca accctgtaaa caataatttt ttcatatttt acctccaaat
    42721 tttaatgtaa ccgatgccgg ttttaatata acgatatcat tttgttctga aaataacaat
    42781 ttataaggta tgattctaaa aaaattatta atgataccaa tactttatat aattcgcgag
    42841 cgctttcttt gaatttttta atctttcgta gcagaatgag aatgtattaa aaatagatta
    42901 ggaggaattt tgatgtttag acaccagaaa gaattgcagt ttgaagcaaa accagatcgt
    42961 ccgaatccat taatcgcgaa atatctgcag gagctgatcg gcggccaata tggcgagatg
    43021 agtgtagcta tgcagtacct gttccaaggc tggagctgcc gaggagaaga aaaatataaa
    43081 gatatgctga tggacattgc aacagaagaa atcggccacg tggaaatgtt ggcgacaatg
    43141 gttgctcgtt tattagaggg tgcgcctgtt gaagatcaag aagcagcgat gcaaaaagat
    43201 ccaacaatcg gtgccattat ctctggaatg aatccacagc acgcgatcgt agctggctta
    43261 ggacctcgtc ctgctgacag cgtgggcaat ccatggagcg gtgcctatat cattgcgagt
    43321 ggcaacttgt tagcagactt tagagctaat ttaaatgccg aatcacaagg aagacttcaa
    43381 gtagcacgta tttacgaaat gatcgatgat cgtggcgtaa aagatatgct gtctgttctc
    43441 cttgcaagag atagctatca tcaaaatcta tgggaatgtg cagtgaaaga attagaagaa
    43501 aaagaaggtt caatcttagt cccaagtact ttcccgcgtg acaaagaacg aaaagacatt
    43561 gcttatgact tctataactt ctcagaggga gaccaaagta gtgaaggttc ttgggctagt
    43621 ggcaaagcac tggatggcga aggcgaatat caatggttga aagaacctaa gatcgaaggc
    43681 gctgcaccaa aattagaacc agtaacacca aaaatgtatg ggacacctcc attcaagaaa
    43741 taaatatcta cccgtagaaa cacccgtttt ttgttccaca cgctttgtga gcaaaactga
    43801 ctaaagtcat taatcataac cacccttcaa aagggtggtt ttctctagag ctataagctc
    43861 aaatcaccgg ccagcgccta aagacgctgg ctttcatatt ttatgttcaa gccatattgc
    43921 ctttgccagt tttgcccacc tcttaaaagg tttatgtact actccttagc ccttaaaagg
    43981 atcgtcttac tctcgtacac tcagcttatc taacgcacta tcatgttttt cttgttcttg
    44041 aatgtacttt ttgatggtcg cttcattttg tcctactttt gtcacatagt atccttccac
    44101 ccaaaagtgt cgatacccaa atttatattt tagatttgca caatctcttg atgatctcct
    44161 gaatattggc tcgatattga ttataaatta tttttcttct atactttggt gtgaatacaa
    44221 tgtggtattt acacatctac tttgtacggg ctaaactatt tccctttatt gctccacccg
    44281 catagcaagt ggttttgtat ttcaatcgct cggcgcgctc aattaggtct aaagacaata
    44341 aatctaaaaa cccgctgctt cactgacaga aacaacgggt tttcagaaaa aaatgaaatg
    44401 aaaaagatct cttacggcaa tctattttat ttttttgatt ttttataaat ggaaaatgct
    44461 tcaagaagtc caagaaataa agccgtataa aaacaagaac ctatgaaatc tttatttatt
    44521 agatattcaa cagaaatccc gataacacta gccaacaata tatttatcag aagtgtaaaa
    44581 taaggatgct ttttatagaa tagaactagt gttgttttca tagactctcc tttcttcata
    44641 tttccaatta atcacaaatt cacggcatta ctagaaaaat taaaggggcg cagaagtgga
    44701 aaaatactct tcgactttcc ctacaaacca ggccatcttg tgtttaataa ctataccaaa
    44761 tctaaggtac ctctaaatct aaattccatt tgtggcggtg acctccaatt tttaactctt
    44821 ctatctccca tccagtatac ataaccttga tacttcgacc acttatatat cgaacacaca
    44881 aatacctatc cattgcagga gtactaccta acttagttgc tacttgcatc taaataacag
    44941 ctgaaaagat aggacttact cttagtaaag tatctgaact attaattttt aaactatcat
    45001 ttttatcctc aactacatgc acatctgttg caacttcact ttctgtctca tccagataaa
    45061 tgattaagga atcgggaatt gcaatatctt cagctgacgc tggaatagtt gagctaaatt
    45121 agtcatcata tctttattat aaaataacca acagcaaaaa atacaatgaa aaacaaactt
    45181 ggaactaatg tatcattaat aaatgttgaa aaattcagca actcattact gtatgatttt
    45241 agcagcccaa ccaacatata ccctataaaa gctaataaga tggttaggaa tcctttagaa
    45301 tttttactca ttcatagaca cttccttaaa taacttttat tatagaaggt attgtaaata
    45361 ataatattga caaaaagtga ctcaaaataa aaaaaacctt acattatact ggaatgaact
    45421 gtattgatag tgtacctaaa agctctactg acataagatc gtgtaatcgg taaagtaatt
    45481 ttattaatta tacgggatgt aatcaattag agaataaact aatcataaaa ggtactttta
    45541 cattcataat tgtcgctttg agattctact ttggttcact atctgaccca attgcacatt
    45601 ttcgatcatt acaagtattg gtgtcgttag aacaactaaa taaaaactag cggtagattt
    45661 ttcagaatct atgctaattt ctgtatggat gttccagtga tggcaaattt ctcttttcat
    45721 tgtttttctt gtcgcatgat atgccttttt gtgttattca gttaaactat agaaattctt
    45781 tcctagacag atcttgatcc caaattttac gtttttgagc atcgatatag tttaaaatga
    45841 cattactcat atctaaagag tttagatttt ttaggactaa aactgtcagt tgttcttttt
    45901 cttctttctg ttaaagtatt gtcgcgactt ttcgtatacg ttaagatatg tcgtgaaaaa
    45961 acaagttttg tgacacaaaa aaacgaatga cttgaggaaa tcacctcaat cattcgttta
    46021 aaatgctata tattctttag tttaagatac ggaaattaat gccatcgacc acactagtag
    46081 aatgaacgac atttacttgg ccttttttta atttcgttat gtttagcata taaaaatatt
    46141 atagagttta cttacaatgc ttaaaacata tactgtataa tctgatcaat tttagccatg
    46201 tcttgcaatg gtaagttttc tatttttttg agttttcgtt ccttaaaatc aagagatttt
    46261 aattgtgtaa taattacttg tccttttata tctagctctt caggtaatga gtaacgtgtc
    46321 ggtaaattct ttatagtgga agtaattgga catatgaccg aaaacattgt tttacggtta
    46381 aattcataac gagagacgac tagtcctggt cgtctttttt gaatttcttt tcctacggag
    46441 ggatcaaaat caatccatac aatatcacct tttttaggaa tataaattct ttcttctgac
    46501 actataaaat ttctctccct tcaggagtta aatcttccca ttcgtctttc tcataatact
    46561 cggcctcttc cccaccacta aatggatctt caatttttgg aactaacgta attgttccat
    46621 catcagaata cacaacgata tattcttggt tttctgaagg tttctttccg ttatcagaag
    46681 gtaaagttac cactacagaa cttccttgta atctagattt tgtaacaagc attatcatca
    46741 ctcccttaat aaaagtatac tatataacac taagtaacgc aaaattcccc tttgtaaact
    46801 atctagaaaa ttgttttgtt taaagtatat cttattggat ataaatagaa ataaattgta
    46861 gccagttcat tttttcttta actaaaaaaa taatccaaga aacattgaac ctatggatcc
    46921 aaaagctacc caaatactat agctaacccc ccgctacctt caattttgca gataaaacgc
    46981 tttgggagaa aatttcaaag acaacaggcc atcctatcat gcccgattat aaacaaaaag
    47041 ctggctattc cttttgctct gacaaatttc aattgggaaa gttcacgaaa ctagcaggtg
    47101 aagaagtttc aactgttcgg atcaaagaat gcccgcttca aatagaaaca ttggttcaac
    47161 gaatttcaac tagacaagac tttgctattg tagaacgtga gatcgtagct atttttgtag
    47221 aagaagggat tttacatgat ccaactcata tcaatgtgga taaatggcaa cctcttatct
    47281 ataaattcag agaatataca actgccaacc agtcgttaac tttgaatttt agattccaag
    47341 aattcaaaga gtcataatga taaacatcgt taggtataaa taaaaaagac tcgcagcacg
    47401 agtaaaaaac aaatagaagc tatacattag aaaggtcgac tgtgacccta tagatgcagt
    47461 atatgcagct tatgagcatt tcttctgttc tctttgtttt tgggatctgt gctgaagtct
    47521 ttttcgtttt ttgccgctct ttctttgaaa aatcgattat gttatacctt ctccattact
    47581 aattcaggca tctgctgagt aatgattttt cgcgcaaaag aaatatctgt tacccaaggt
    47641 tcgatttgtt cttcagtcaa gacaagcggc attcggtcat ggattggtgc gactgtgcgg
    47701 ttaggttcag tagtcattat gattgattct gccatttttt catcctgatg gctacgataa
    47761 aaaccgccaa tatacactat tttttcctta tttgaaaaca taaatttgtc tttttcttca
    47821 ttccactcat tgggaaaaca caacgatttt gcaaaaatgg ttgatgaaag gtcttttttt
    47881 cttctactgt ctctgcacgg gcattaatca tcaattgtcc ttttttaaat ccggtaaatc
    47941 cccacttcat gatttccgga gtgaggatgt tttcttcctc ttttcttaac gtcacaacaa
    48001 gatttgacgg aaaaacttct ccagctgcta attctgctgc ctgcttcggt tgtttcgtct
    48061 gggcttctcg ataataattc tgaaggagct ctgactctag atcaaaaaaa taacgaccac
    48121 acatcctaat ccctcccaat ctttttttct atcatacact gcaacaagaa gttcgcacca
    48181 acaaaacgct ttcaattttt gtagaactaa aaaagttgtg acaagtgaca aactctccag
    48241 tgaatggtat tctcctgcca actcctcggt cacaagtcac aatattcaac aaacatgaga
    48301 agctgctttt tgaaattgtt ccttgtgact cggagtgaaa cggcaggctt acgacctctg
    48361 ggtaaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtag
    48421 aaagctattt tcacaaaatt tttcttaata ctcgaaacta agcgactttt tcacaacctc
    48481 ttccttaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat
    48541 atgagcagct atttttattt ggctgttctt attacttgat gcagggcagc tttttcacaa
    48601 cctctccact aaacggtgtt caatcagcta accttcggta ttagctcaaa aaacggcaaa
    48661 atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaagcg ctgatttcac
    48721 aacctctaat acacggtgtt ccagaagtag cttcttcga
//
LOCUS       DACGLI010000017        47471 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.018, whole genome shotgun sequence.
ACCESSION   DACGLI010000017 DACGLI010000000
VERSION     DACGLI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.018"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(56..790)
                     /locus_tag="IXT22_001031"
     CDS             complement(56..790)
                     /locus_tag="IXT22_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4862412.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1117..1527
                     /locus_tag="IXT22_001032"
     CDS             1117..1527
                     /locus_tag="IXT22_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAQ4862413.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1520..2221
                     /locus_tag="IXT22_001033"
     CDS             1520..2221
                     /locus_tag="IXT22_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAQ4862414.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2221..3807
                     /locus_tag="IXT22_001034"
     CDS             2221..3807
                     /locus_tag="IXT22_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4862415.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3826..4047
                     /locus_tag="IXT22_001035"
     CDS             3826..4047
                     /locus_tag="IXT22_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAQ4862416.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4044..4805
                     /locus_tag="IXT22_001036"
     CDS             4044..4805
                     /locus_tag="IXT22_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAQ4862417.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5185..5694
                     /locus_tag="IXT22_001037"
     CDS             5185..5694
                     /locus_tag="IXT22_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4862418.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5769..6308)
                     /locus_tag="IXT22_001038"
     CDS             complement(5769..6308)
                     /locus_tag="IXT22_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAQ4862419.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="IXT22_001039"
     CDS             complement(6448..7059)
                     /gene="rpsD"
                     /locus_tag="IXT22_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAQ4862420.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7375..8172
                     /locus_tag="IXT22_001040"
     CDS             7375..8172
                     /locus_tag="IXT22_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAQ4862421.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8200..8835
                     /locus_tag="IXT22_001041"
     CDS             8200..8835
                     /locus_tag="IXT22_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAQ4862422.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8855..9628
                     /locus_tag="IXT22_001042"
     CDS             8855..9628
                     /locus_tag="IXT22_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4862423.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10036..10833
                     /locus_tag="IXT22_001043"
     CDS             10036..10833
                     /locus_tag="IXT22_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAQ4862424.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10811..11224
                     /locus_tag="IXT22_001044"
     CDS             10811..11224
                     /locus_tag="IXT22_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862425.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11208..13853
                     /gene="mutS"
                     /locus_tag="IXT22_001045"
     CDS             11208..13853
                     /gene="mutS"
                     /locus_tag="IXT22_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4862426.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISSVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13871..15979
                     /gene="mutL"
                     /locus_tag="IXT22_001046"
     CDS             13871..15979
                     /gene="mutL"
                     /locus_tag="IXT22_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAQ4862427.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16001..16561
                     /locus_tag="IXT22_001047"
     CDS             16001..16561
                     /locus_tag="IXT22_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAQ4862428.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16646..18634)
                     /gene="treP"
                     /locus_tag="IXT22_001048"
     CDS             complement(16646..18634)
                     /gene="treP"
                     /locus_tag="IXT22_001048"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAQ4862429.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18857..19570
                     /gene="treR"
                     /locus_tag="IXT22_001049"
     CDS             18857..19570
                     /gene="treR"
                     /locus_tag="IXT22_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAQ4862430.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19647..20093
                     /gene="msrB"
                     /locus_tag="IXT22_001050"
     CDS             19647..20093
                     /gene="msrB"
                     /locus_tag="IXT22_001050"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAQ4862431.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATEQPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20263..20865
                     /gene="ruvA"
                     /locus_tag="IXT22_001051"
     CDS             20263..20865
                     /gene="ruvA"
                     /locus_tag="IXT22_001051"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAQ4862432.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNEKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20878..21879
                     /gene="ruvB"
                     /locus_tag="IXT22_001052"
     CDS             20878..21879
                     /gene="ruvB"
                     /locus_tag="IXT22_001052"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAQ4862433.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21908..22486
                     /locus_tag="IXT22_001053"
     CDS             21908..22486
                     /locus_tag="IXT22_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4862434.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22538..23020
                     /locus_tag="IXT22_001054"
     CDS             22538..23020
                     /locus_tag="IXT22_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAQ4862435.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIAIEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23137..23511
                     /locus_tag="IXT22_001055"
     CDS             23137..23511
                     /locus_tag="IXT22_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862436.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="IXT22_001056"
     CDS             complement(24189..25541)
                     /gene="brnQ"
                     /locus_tag="IXT22_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4862437.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25688..26278
                     /locus_tag="IXT22_001057"
     CDS             25688..26278
                     /locus_tag="IXT22_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4862438.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26406..27755)
                     /locus_tag="IXT22_001058"
     CDS             complement(26406..27755)
                     /locus_tag="IXT22_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862439.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27923..28663)
                     /locus_tag="IXT22_001059"
     CDS             complement(27923..28663)
                     /locus_tag="IXT22_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862440.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28676..30268)
                     /locus_tag="IXT22_001060"
     CDS             complement(28676..30268)
                     /locus_tag="IXT22_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4862441.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(30836..31132)
                     /locus_tag="IXT22_001061"
     CDS             complement(30836..31132)
                     /locus_tag="IXT22_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862442.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31308..32033
                     /locus_tag="IXT22_001062"
     CDS             31308..32033
                     /locus_tag="IXT22_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAQ4862443.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32026..32868
                     /locus_tag="IXT22_001063"
     CDS             32026..32868
                     /locus_tag="IXT22_001063"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAQ4862444.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32871..33392
                     /locus_tag="IXT22_001064"
     CDS             32871..33392
                     /locus_tag="IXT22_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAQ4862445.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33645..34208)
                     /locus_tag="IXT22_001065"
     CDS             complement(33645..34208)
                     /locus_tag="IXT22_001065"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4862446.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34459..34728
                     /gene="rpsO"
                     /locus_tag="IXT22_001066"
     CDS             34459..34728
                     /gene="rpsO"
                     /locus_tag="IXT22_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAQ4862447.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34916..37042
                     /gene="pnp"
                     /locus_tag="IXT22_001067"
     CDS             34916..37042
                     /gene="pnp"
                     /locus_tag="IXT22_001067"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAQ4862448.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37552..37818
                     /locus_tag="IXT22_001068"
     CDS             37552..37818
                     /locus_tag="IXT22_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4862449.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37962..39953
                     /locus_tag="IXT22_001069"
     CDS             37962..39953
                     /locus_tag="IXT22_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAQ4862450.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40307..41608
                     /locus_tag="IXT22_001070"
     CDS             40307..41608
                     /locus_tag="IXT22_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4862451.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41738..43108)
                     /locus_tag="IXT22_001071"
     CDS             complement(41738..43108)
                     /locus_tag="IXT22_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAQ4862452.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43290..43613)
                     /locus_tag="IXT22_001072"
     CDS             complement(43290..43613)
                     /locus_tag="IXT22_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4862453.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43938..44546)
                     /locus_tag="IXT22_001073"
     CDS             complement(43938..44546)
                     /locus_tag="IXT22_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAQ4862454.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44876..45592
                     /locus_tag="IXT22_001074"
     CDS             44876..45592
                     /locus_tag="IXT22_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAQ4862455.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45605..46300
                     /locus_tag="IXT22_001075"
     CDS             45605..46300
                     /locus_tag="IXT22_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAQ4862456.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46384..47013
                     /gene="udk"
                     /locus_tag="IXT22_001076"
     CDS             46384..47013
                     /gene="udk"
                     /locus_tag="IXT22_001076"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAQ4862457.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15393 a         8788 c         9877 g        13413 t
ORIGIN      
        1 aataaaaaaa cttggtacgc aatcgctgta ccaagttttt ttatttagct tttgattaag
       61 ccataaataa taatttatat aagaatactg ctacgacacc agcacagata ggtgctacaa
      121 ctggtaccca tgcatatccc cattgagaag aacctttatg tttcaatgga agaagtgcgt
      181 gtacaagacg tggagcaaag tcgcgggctg ggtttagtcc aggacctgta ggaccaccaa
      241 gtgaagcaac taatgtccat acaaggaaac caagtgctaa gtgagctgta ccaagattat
      301 cttggaagaa tggtgctttt gtaataccta gggcaccaaa gaataaaacg aatgaaccaa
      361 agaattcatt gacgaaacca ttgaatttag aaccaacgct gttgattgtt gagaatgtac
      421 ctaacacatg gtttacgtct tctgtttggt cgtagtaagg tttgtaacaa gctactacga
      481 tcaattgtcc aatcgctgca ccaatcaatt gtgcaatgat ataaggaaca acttcagccc
      541 aagggaatag accattagat gctaaagcaa ttgtaaatgc tgggttgatg tggttaccgc
      601 tgattccacc aaaaatcatt gctggcatca taaccccgaa tccatacccg acagcaatca
      661 gcatccagtc actgccatat ccttttgtac cttttaaatc tacgtttgct acagcaccgt
      721 tacctagaac gattagtaat gctgtaccaa tcatttccgc cgcaagacgg gtcattagtg
      781 agtaatccat aaatacctcc aaaagttata aaaatgcaaa aaaaaaagaa acatcaacac
      841 gaaaagcatc ggtgcagtgt ttcgtgtcgg aaggatttct gcagtcttaa caaatgtgaa
      901 taaaaaaatg aattccatta cttataagaa accagaccaa cagtaaaact ccaactcttt
      961 ttaaaagttc tccacaaatc accaagctta actataaata taccaaaaaa aaaacgtttt
     1021 ttttctcaaa aattgtatct tagaaacagc atgttttgaa actttcagaa aaggtttgtt
     1081 agtaaaatga aagctatacg taaggagtgt tgtttgatga aattttttca agagtttttc
     1141 attattattt tcttttctgt attaggagaa ggcatacgga tttttgctca tttacctatt
     1201 cctggaagta tcttaggtat tcttttttta tttttagcat ttgaaatgca tcttgttgat
     1261 cctgaaaaaa tcggagcaac tggtgatttt ttattgaata atctagccat tttatttgtt
     1321 cctgctggtg taggtttatt ggaatatttt gatgatattg cttcgatatg gcctgtttta
     1381 ctgggagcag tcgtcgtgtg ttccatcgtc acgatggttg cagcgggaaa aacggcagaa
     1441 ggtgtagaag ctttgctggg ctatgtccgt aagaaaaaag cagaaagggt atctgtaaac
     1501 gaaatggagg agaatcaaat tgactgagtt ttttgtgaat ccattatttg gcttaagttt
     1561 gactttagga gtgtacgtat tatctgacaa atttttgcgg aaatataaac tgcctgtttt
     1621 gaatcctctc gtattatcga ttgttgttat tatcttattt ttgcattttt ctgggatcag
     1681 ctataaagac tataatatcg ggggcaattt tttgactatg ctgattactc ctgcgacagt
     1741 ggcacttgcc atccctcttt ataaaaactt ccgtttactg aaagagaatt tttatcctgt
     1801 aatggctgcg attttagcag gaatagtcgc aaattgcttg gttagtgtag ggttcggtta
     1861 cttcttctct cttcataaag agatggtgat ctcattacta cctaaatctg taacgacggc
     1921 tatttctgtc gatttatctc atacgatggg cggggtgaat gccgtgacac ttgctattgt
     1981 tgtctctaca ggtatttttg gttcgctgat cgccactcat attttccgcc tattcaagat
     2041 cgaaagtcca gttgctcgcg gtgtggcgtt aggaagtact tctcatgcta ttggtacagc
     2101 aaaagcaatc gagattggtg aaatagaagg aatcatttcc ggacttgcga tatgcgtcaa
     2161 cggaatattg accgttttat tgctaccgtt attctttcag ccttttgctg gcttgttttg
     2221 atgcgaaaac cactatttta tgctacaata accaaaacgt tcgagcataa aaaaggaggg
     2281 aaagacgtgt atttgtcttc cgagtatctt aaacaatttg ataaagatct atattataag
     2341 attctcctcc tagaaagttt tgaggatcaa gcttggcata ccgctgcaca attagcgcaa
     2401 gttgttcagc tggatgcccg cagcgtgtcg aaatacctga acgagctgtc taaaaactat
     2461 cagcagttta gcggtaagac acaccctttg tttacaaaaa atcaccgttc tggttataac
     2521 ttttatgata cgctcgattc aattgaacat gagcgttttt tgatctatct cgtgcaaagt
     2581 acgctgaaat tccagttgct gcacgacatt ttttttgaag aattccatac aatgtaccaa
     2641 tttgcgcaaa agcattacat tagtgaatct actgctcatc gaaaaatcaa tgaatggaaa
     2701 cagcaactgc aaacttacgg aattcggctg caacgaggta catatatcgc tcaaggcgaa
     2761 gaagaaatca ttcgacttta cttgcatatg acattctggc agttgtttcg agggaaaatc
     2821 tggccatttg aaacgatttc tcaaatggac gtaaagaata tggcagaaca tatcatggct
     2881 ttttttaatg ttcgtctgaa cgagatcaaa aaaagacgat tggaatatat gctaggtgcc
     2941 ttttttttaa gaaaatcaca gaagcattat gttgtattga atgagaaaaa aagacggctg
     3001 atttctgaca atctgttgtt ccagcgattt tgccaggtca tggagccggt atttcctaat
     3061 tattttcaag tagaagacga gttaggcgca ttatttcttg tactgatgac tcgtgaagaa
     3121 tattatagtg atcctaagat acggaagaaa atttttgatt ttcatcaaca agcaaaaaca
     3181 ccgcccttta cagccctttc agaagcaaaa gccgctcttt ctctttatca ggaagagcag
     3241 gggctgccag cagaaaatct aaccttcgag gcagaaaact atttattcag cagtcatttt
     3301 ttcgcctatc tttttcctaa tgcgaaagaa acgattgatg gcaatagtag tgattttatt
     3361 aatcatttag ttattgaaaa caaggaattg aaacaatggc tcgtacattt ttttgaaagt
     3421 agacacaaac atcccaatca tctggcattt aaaaatcatg cgtttttgat ggggcggtat
     3481 ctgactgtgt ttaaaacatt aggagccttt actccacagc ttccaaagat cacgatcctt
     3541 ttaatgacag atttcccatt atttgaagag caactgttag aggagggatt acggacattt
     3601 ttccgtaatg agtatcagct gatttttctg ccaacagatt atcgggggag agaagttgat
     3661 cttctgattt cgacaagtaa agtccaccgc aaaccatggg cggatcttga ctattttatt
     3721 gtgactgaag aactaaaatt aattgattac atccaactat ctcaaaaatt tgaaatgatt
     3781 caaaaacaaa aactattaaa acaataacaa agaaggagaa aaaagatgac atttgaagaa
     3841 attttaccag aattgaaaaa aggtgcaaag attattcgta aaggatggag tggatttgaa
     3901 ctttatgttg ttctcgtatc cgatgatgaa tttgatggct gtccggtgac gccgtactta
     3961 ttgatcaaaa caagtgacga aggtttttcc agcttcgctc ctacagtttg tgatatttta
     4021 gcagatgatt gggcgatcgt agaatgaaaa accagtatcc agatctagct aaacaggttg
     4081 tatttatcac aggagctgct tctggaattg gtgctgcgca agcccgagcg tttcttgaac
     4141 aagatgcttt tgtatttgga ttagatcaaa agttcggtaa aatggaagaa atttctttgc
     4201 gatttcctga aacttttgcc tacgcactag gtgatgttcg acaaatgaaa gaactccaac
     4261 aagcggtatc gaaatgccaa aatcattttg gtgaagttac gattttactg aatacagcgg
     4321 ggatattgga tgcctacaaa cccttgatgg aaactgacga atcgctgtgg gatctgattt
     4381 atgagacgaa tgtgaaaagc atgtatcagc tgacaaaaat catccttcct gatatgatcc
     4441 gccaaaaaag cggaacgatc atcaatatgg cttcgattgc tggcttgatt gctggtggag
     4501 gtgggatcgc ttatacaagc gcgaaacatg cgattgtcgg atttaccaaa caactcgctc
     4561 tggattacgc aggacagggt atccgagtaa aaggaattgc tccaggagcc atccaaacac
     4621 caatgaatgc ggctgatttt gaagggaaag gtgagatggc agagtgggtg gcaaatgaaa
     4681 caccagtcaa gcgatgggca cagccggaag aagtagctga gctgacgtta tttcttgcct
     4741 ctcctcaagc aagctacata caaggaacga tcatcccaat cgacggcgga tggttgttaa
     4801 aataaccttg tgtttttttc aagcttctgt atgataaaac taaagagaga aacaacggtt
     4861 gatgataaaa aaagtcgatg actgttcccg acattcgatg ccgaacagcc agttcaaaaa
     4921 attcttttta ataatcgtta atattcgaaa ctaagcggct tttcacgacc tcttgatata
     4981 aacgatattc aaaagcttgc aactgcggta acaagtccag ccaaatgaaa aatataagga
     5041 gctattttta tttgaccatt cttattactt gttgcagggc agctttttca ctaccttctg
     5101 cgacacttca gttggaattt tcttcccatc ctttggtcgc ggtcattacc aagataaaat
     5161 tatcttgcaa aggagaaata gaacatggaa aaaaataata cccgttcagc caaacgctgg
     5221 acaacgacag atgtgactcg gatggcgcta gtcactggtt tatatgtggc agtgacgctg
     5281 gttttgtctg tctttagctt tggagtgatt cagattcgtc tctcggagat gttcaactat
     5341 ctgtccttgt ataacaaaag atacatcgtc gcggtaacag cgggagtagc tttggctaat
     5401 attgcttctc ctcttggact gatagatgtt gcagtaggaa gcgtcagcac gctgcttgta
     5461 ttgcttatca actataaaat cactagtcgc atcaaaaaca tgaaaatcaa aatggccgtg
     5521 acagcatgcg tatttgcttt ttccatgttt acagtagctg gtcagctaac gattttatat
     5581 caactacctt ttttcttgaa ttggtgggtg attgctttag gagaattggc atcaatgatt
     5641 gtcggtggga taattattta ttggatcggt aaaaaagtgg atttgtcaaa ataaagatct
     5701 gtttaattta aaatagggca gcatggaaga gactgaatgt tgagtcttct tccatgctgc
     5761 ttttttgatt aatttgtatg aagaaatcga tttagccgtt ttttcatcaa gataccgata
     5821 taagctgctc cagttgcctt gattgcttcc ggcagtaaaa acggcagtag tccactggca
     5881 aatgcagttg taaaagtaag atcaccactt attttcagcc agatcgttcc gcagatcaat
     5941 gcagcaagag agcccattag attggcaaag attgcatata agtaatgagc atccgttctt
     6001 tcgatcatcc aaccagttat ccacgtttgt aagagaaatc caatcaaata tccgccagtt
     6061 ggcccaaata aaacagctat acctccagtc atccctgaaa atacaggaag accaatcaag
     6121 ccaagtaaaa gataaactcc aacagatatc aatcctagtt ttcttccgag aaaagttgct
     6181 gttaatccaa tagcaaatgt ttgccctgtc aaaggaacca aaccaaaagg aatggtcatc
     6241 tgagaaagga cagaaataat cgcggcaaat tccgcagcaa gtatcaattc tttcaatgtt
     6301 cggttcataa cgccctcttt tcgttaactt aatattttta tttggttaac gaaattgtaa
     6361 aacaaagtga ttactttgta aatagaaaat ataaaaaaag accagctatc caatagatag
     6421 cggtcttttt caagaaagct tttgaaatta taagctttgg ttgtagtatt caacgacaag
     6481 agcttcgtcg atttctggat atagttcgtc acgttctggt aaacgagtca atgaaccttc
     6541 caatttttca gcgtcaaagc ttacgaatgc tgggcgtcca acagttgctt ctacagcttc
     6601 ttttactgtt acgatgtttt gtgatttttc acgaactgag atcacttgac ccacttctac
     6661 gtggtatgaa gggatatcaa cgcgtttgcc atcaactaaa atgtgaccat ggttaactaa
     6721 ttgacgtgct tgacgacgag tcgttgcaag tcctaaacgg taaacaacat tgtctaaacg
     6781 ttgttctagt aagatcatga agttaacacc atgtttacct tctttgattt tgctagcttt
     6841 tacgaacaag ttacggaatt gacgttcgtt cattccgtac atgtgacgaa gtttttgttt
     6901 ttcagttaat tgcatgccgt attctgattg tttgccacgg ctattaggtc catgttgacc
     6961 tggtgcgtaa gggcgacgtg ctaattcttt tcctgtgcct gacaatgaga tgcctaagcg
     7021 acgagaaatt ttccatgatg gtcctgtata acgagacatt aaaatttcct ccaatgaata
     7081 taagtttttg gagtaaaata atccgttgaa aaattcataa tcatatagtt tgttcttcaa
     7141 tcttcacctt tgcagccgcg gttacacaat cgaacccgag acggggcaac aaactaggga
     7201 tgagttatta tttttctgct gcattatttt acacaaatta cagtatatga tagatcatcc
     7261 acgaatgtca agataattag tacataaaaa cgctttacaa acctaggctg tctttataaa
     7321 atgagagggt atgtgcaaat ggaaaaaagc gaaggaagtt taaggagaaa atcaatgaat
     7381 ccggtatcac cattatttga gaaaatcgat gcttcaattg aaaagaaggc gaatcttttt
     7441 gaaaacagct tttcacgtta cgctgttcga gcggttctcg cctgtttgtt tttgacttta
     7501 ggaacggctg tggcatttgc gatcgcgatg aagggggaag atatcgcgca tggtctagga
     7561 aagattttat acgcatttat gttcagctgg ggtctggtca tgattctata catgaacgcc
     7621 gaattaggaa catcgaatat gctttatatg accgtgggtg tttttcggca gagacttgct
     7681 ttaagtaagg cagccaagat tctatttgcc tgtatttttt tcaatatgat tggcggtata
     7741 ttatgtggat ttctaatttc tatgactacg ccatttcaag atttaacgtt ggacaacttt
     7801 atgttagaat caatagcagt aaaactagca aaaccttcag caacgatttt ggtggaaggg
     7861 atgtttgcga atatcgttgt caataccgct gtactgatca gcatgcggat gaaagaggat
     7921 gtcggaaaag tgatcacagt cgtattcatc attttcattt ttgctttttt aggatatgaa
     7981 cacgtgatag cgaattttcc tgcctttacg cttacttact ttgcttctca cggacagatg
     8041 gatggaatga cagtcagcaa tgtgttacat aatttgtttt ttgctttggc aggaaattat
     8101 attggtggcg gtttagtaat gggactggga tatgcttggc tgaatcagtc aaaatcatcc
     8161 tatgtggact aaaaagtcgt tcattaaagg ggaagtgcca tggaagtttt agtttttcca
     8221 aaaaatgagg aaaaagcgtt acaaatggaa aagtacatga aaaatctttt ttcctttgct
     8281 ggagtaccta agccggaacg cgctctttta caacaaccgt tactggatga gagcaaaaat
     8341 ttatctattt ctgaagtttt agcttttgtt cattattatt atgaacaaat cgaaagagag
     8401 tatcagtatg tagcgatcga tttagtccag aaaaacatca aacggcttac atttgaagac
     8461 ttagtcgtat tgttgccact agttcagaaa aaagaatggt gggacagcat cgactcttgg
     8521 agaaaagtat acagcacatg gtgtaaagcc tacccagagc agcgtgaaga agtctttcaa
     8581 ttgtttgaaa aaaaggaaga tttttggcta cgtcgaatag caatcacgtt gcaattaggt
     8641 tataaacagc aaacagacac aggactattg atccgagcaa tagacgaaga tcgtcaaaca
     8701 aaggaattct ttatccaaaa agcaattggt tgggcattac gcgattatag taagaccgat
     8761 gccgattggg taaaaagaca gctgacaaca gatttgagta agttagctgt tcgagaggca
     8821 agtaagtatt tataagaaag cgagacgaca agagatgaga cgcaaattat ttgcttttga
     8881 tattgatgga acgttgttag attcaaacaa acaagcttta gatagcacaa gagaagcatt
     8941 ggaaaaatta cgcaaagccg gtcatctggt cacgattgct acagggcgga gccgatttca
     9001 tgcgcaagag atcattcgcg atcttgattt tacgaactac attttatgta atggagcggc
     9061 cggtttttta gaccatgaac aagtatataa gaatttacta gatcgcgacc agttggatgc
     9121 gttcgttcaa gaagcgcatc atgagcagat cgatacagct tttgtcagct tagacaatat
     9181 caagcgttct tcttccaatg atgtaacggt gatggaagaa gcgatgcatt ctttcggtgc
     9241 tgtcttgcct gaattagatc agttttttgc agaggaacaa gaaatatacc aagcgttagc
     9301 atttttcgat caaacatatg atgggaagtt ctcttcatat gataaaattc gatttgtccg
     9361 ctggcatgag aacagtgtag atgtcgtacc taaaaatggt tctaaagcag cgacaattct
     9421 gcacttagca gaacaagtag gcatccctca tgaagacatc atcagctttg gcgatggaca
     9481 aaacgaccgt gaaatgttgc gcatgtcagg aattgggata gctatgggga atgctgtgcc
     9541 agaagtacaa gcagaagcta agatggtcac tgatacaaac gatcaggatg gaatttggaa
     9601 ggcattgaaa gagttaagcg tgatttaaaa gaggttgtga aaaagctgtt ctgcatcaag
     9661 taataagccc agccaaacaa aaatagctcc tcctattttt cgtttttctg ggcttattac
     9721 cgcagatgca agctttcgaa caccgtttaa ggaagaggtc gtgacagaag tggtcagttt
     9781 caagaaataa gaagggattt acgaaaattg cttctcaaat ttttgtaaaa ttacggctta
     9841 tttctgaaga agtagatgaa acaacgttta ttcgggaaat gggactgtga caagatgttt
     9901 gtcatagtcc cattttttta ttttattttt caaaactaag aaataccagg aaagagttcc
     9961 ttttgtttga ccttttcttt cttattgaaa acaactataa tatagagtga tgttaaaaga
    10021 gaagaggaat ttagtgtgcg ggtattgttt attggtgatg tagtaggttc aatgggacga
    10081 gagatgatta ctgaatatct tcctagattg aagaagaagt accgtccgca agtaacgatt
    10141 gtaaatggtg agaatgccgc ttctggacgt ggaatcacag aaaaaatcta taaaaaattt
    10201 ttgcaagacg gcgtagatgt cgtgacgatg gggaatcata cgtgggacaa ccgcggaatc
    10261 tttgagtttg taaatgaagc taaaaagatg gttcgtccgg caaattttcc ggaagggacg
    10321 cctggacaag ggatggtctt tgtcaaagtg aaccaagtcg aactggcagt gatcaacatg
    10381 caggctcgtt cttttatggt ggacttggat gatccttttc gtaaaatgaa tgagctggta
    10441 gaagaagcca gaaaacgtac gccgatcatt tttgtagatt ttcatggaga aacaacaagt
    10501 gaaaaacaag caatgggctg gtttttagat gggaaagttt cagcagtggt cggtacacat
    10561 acacacgttc agacaaatga tgcgcgaatt ttgccaagag gaacagcgta tctgacagac
    10621 gttgggatga caggtcccta tgatggtatt ttgggtatgc gcagagaacc tgtaatcgaa
    10681 aagtttctga ctgcattacc aaaacgtttt gaagttgtgg aacaaggccg atcgatttta
    10741 agcggctgta tcttggaatt ggatgatacg acaggtcatg caaaagaaat ccagctgatt
    10801 cagatcaacg atgatcgacc gttcatggag tagaaagaga ggcagttttt tgcagcagga
    10861 gccggaaatt caaaaagaag taaggaaact gacaaaactt ttaagagaga atgaaacgat
    10921 cattcgctac aaagaacttg aagaaaagat ccagcaaaac cagtatttag ctgagttgag
    10981 agaaaaaatc aaacaagcgc aaaaagatgc tgttcatttt gcccactatg acaaaccagc
    11041 agcagaaaaa gaagcaatca aacaagcgga tcaattcatg caagaatttg atcagcatcc
    11101 gcttgttgta gcttatagaa aacagctgtt ggaagcagat gatctgcttc atcatttaac
    11161 aactatgata caagaagaaa tcaatggaca aatagaggag gaaaaacatg cctcaaaaaa
    11221 ctaaaaatac tcctatgatg gaacaatatc taagcatcaa ggcccaatac caagatgctt
    11281 ttttgttcta tcgtttagga gacttttatg aactatttta cgaagatgcg atcaaagcgt
    11341 cacagctttt ggaattaacg ttgacgagca gaaatcgaaa tgcagaagaa cctattccta
    11401 tgtgcggtgt acctcaccat gcagcacaag gatatatcga tgccttgatt gaaaaaggct
    11461 ataaagtagc gatttgcgag caggtagaag atccaaagac gactaaaggg atggtcaagc
    11521 gcgaagtgat ccagctagtc actcctggta cagtcatgga cagcaaagga ttgtcggcaa
    11581 aagacaacaa ttttttaaca gctgtagtta gtcaaggaaa tgaatttggc tttgcttatg
    11641 ccgatttaag tacgggagaa ttgaagacgg ctcggttgca tgatgaagaa gctgttttaa
    11701 atgaagcctc tgcattgcag acaaaagaac tcgtattagg cagtgagatc actgataccc
    11761 ttcgtgaaca gctaagcggg cgtttagggc tagtcttttc tcaacaaaat gagatggaag
    11821 aaaacgcgga atttagcttt ttgacaagcg aactagtcga tccgctggaa aaagaagcaa
    11881 ccggcaaact attgacttat ttatcggtga cacaaaagcg gagtttagct catatccaaa
    11941 aagcagtaga ataccaacca gatcattttt tgaaaatgga ttattattca aaattcaacc
    12001 tagaattaag ccaatctatt cggactggga aaaagcacgg cactcttcta tggttgttag
    12061 atgaaacaaa aacagcaatg ggtggccgtt tactaaaaca atggctagac cgtccgctta
    12121 tccaggcaaa acaaattaaa gcaagacaag aaatggtcgc ttctttgcta gacagctatt
    12181 ttgaacgtat cgatttgcag tcagcattaa cgaaagtcta tgatctggaa cgcctagcag
    12241 gtcgagtagc tttcggtaat gtcaatgggc gagacttgat ccagctgaaa acttctttag
    12301 aacaagtgcc aatgatcaga gggttgattg aaggaatcga tcaaggtcaa tggcaaagtc
    12361 tgctttcaga aatgcagccg atggaccatc tcgtccaatt gatcgaccaa gctatccaag
    12421 atgatccgcc gttacaaata acggaaggaa acatcatcaa agatggattc aatgagcagc
    12481 tcgatatgta ccgttctgct atgagaaacg gaaagaaatg gttggcagaa cttgaagcaa
    12541 aagagcgtca agaaacagga atcaagaact taaaaatcgg atttaaccgc gttttcggtt
    12601 attatataga aattacaaaa gcaaatcttg gaaatgcaga actggagaag tatgaacgaa
    12661 aacaaacttt agcaaatgca gagcgtttca tcacaccaga actaaaagaa ttggagacac
    12721 aaatcctcga agcagaagaa aaatctgttg atttagaata tcagttgttt ttagctgtga
    12781 gagaagaagt caaaaaggct atccagccgc tacaagtact tgcaaaagca atcagttcag
    12841 tagatgtgct acaaagtttt gcaacgatca gcgaacgcta tcagtatgtt cggccagaac
    12901 ttgtcagtga caagcatcag cttctgatca aagacggacg acatcctgta gtagaaaaag
    12961 tattaggaca tcaggaatat atccctaaca gcgtagaaat ggcagaagac gaaatgatct
    13021 tgctgattac aggaccgaat atgtctggta aaagtacgta tatgcgacag ttggcattaa
    13081 ctgttctgat ggcgcaaatg ggctgtttcg ttccggcaaa acaagcagtt ttacctattt
    13141 ttgatcggat ttttacccga attggtgcaa gtgacgactt aattgctgga caaagtactt
    13201 ttatggtaga gatgatggaa gccaatcaag ccctgcgtta tgctacgcca aacagtttga
    13261 ttttgtttga cgaactaggg cgaggaacag caacctatga cggaatggcg ttggcccaag
    13321 caatcatcga atatatccat cgtcatgtac aagcaaaaac actcttttct actcattatc
    13381 atgaactgac ggtacttgag aaagaacttc cgcagcttaa aaatgtccat gttggagccg
    13441 ttgaaaaaga cggagaagtt gtcttcttgc ataaaatgat ggatggacct gcggataaaa
    13501 gctacggcat acatgtggca aagatcgcag gattgccttc caatctacta gaacgagcag
    13561 cagatatcct gcatacgcta gaaaatggcg ataacggaca ccatactgtt ccagctgaag
    13621 tagaagagaa aactaaaaca gccaaacagg agcaaataaa accacctgca gaaaaagtaa
    13681 atcaagacca tatacaagac cgtgtaaaag aagaaaacca acagctttct ttattcagtg
    13741 aattatccga aaatgaaaca gaagtcattg aatcactgaa gcaaataaat ttactagaaa
    13801 tgacgccaat ggatgcacta aacacattat atgaattaca aaaacaactg taggaagaag
    13861 gcggatatcg atggccaaaa tccaagaatt atctgaacgt ttagctaatc agatcgctgc
    13921 gggagaagta gtggagcgac cagcttccgt tgtgaaagaa ttagtggaaa atgcaattga
    13981 cgccggcagt actcagattg atatcttagt tgaagaagcg ggactgcgga cgatccaagt
    14041 gattgataac ggagaaggca ttttggcaga cgacgtagag aatgccttca agcggcatgc
    14101 gacaagtaag atccataatc gcgacgatct ttttcgcata cgaacgctgg gctttcgagg
    14161 ggaagctttg ccaagtattg cctctgtttc tgaaatgact ctggaaacgg cgaatcagga
    14221 agaaaaacaa ggcacctatc tgtcgctgaa aggcggagaa gttattgagc atcgaccagc
    14281 accactgcgt caaggaacga agattaccgt cagcaatctg tttttcaata cgccagcccg
    14341 cttgaaatac gtgaaaacac tgcacacaga attagcgaac atcggggaca tcgtcaatcg
    14401 actggcattg agtcatccat cgattgcttt tcgtttagta catgatggaa acaaaatgct
    14461 ggcaactgct ggaaatggcg atctgaaaca aacaattgcg ggaatctacg gattatctac
    14521 cgcaaaaaaa atgctgaaaa tcgaaggaaa agatctagat tttgagttat ttggctatgt
    14581 ttcattgcct gaggtgactc gtgccagtag gaattactta tcgacgatca tcaatggacg
    14641 ttttatcaag aacttttcct tgaataaagc aatcgttgca ggttatgggt caaaattaat
    14701 ggtcggtcgt ttccctattg ctgtattgga aatcaaaatg gacccgcttt tagtagatgt
    14761 aaatgttcat ccgacgaagc aggaagtccg gctgtcgaag gaaaaagaac taacagagct
    14821 aattagtaac gccattcaaa aagcattgtc tcaagaaaat ctgattccaa gtgcagcgga
    14881 taatctacgg tttaagaaaa aagtacctga tcagcctaaa acagaacaaa tcgaaatcga
    14941 tttgtcctac gcttttgaag aagaaaaacc taaaaagcca agtagtttga attttgatcg
    15001 agagacaggt acctttttcg tagaagaact aaagaacaca tttgttgaca gaattgttga
    15061 taagtctgtg gaaaatgttg aaaactattc tggtttttct gaagaaaaca ccacttatcc
    15121 agaaaaaaca gcgaaaacgg tggataagtt tggtgaaaat gttgataact ttgtagaaaa
    15181 aacagtggaa aaatctgaaa agaaagaatt tcccattgtg gataacatgg agaaaacaaa
    15241 tgaagaacaa gcagataaat ccgtagaaga ggatgaaaag atttacgagg aagaattgac
    15301 actccatcct gaatttgatt tcactcaagg aaacgacaaa acattagaac aagccatcaa
    15361 gaaattagaa acggaaaaac cagtacaacg ttttcctcag ttggaatatt ttggacagat
    15421 gcacggaacg tatctttttg cccaaagtag cgatgggttg tacatcattg atcagcatgc
    15481 tgcccaagag cgcattaagt atgaatattt ccgggaaaaa attggggaag tatctgatga
    15541 tctgcaagaa ttgcttgttc catttgtgtt agactatcca aacagtgatg ctttgaaatt
    15601 aaaagagcaa aaacacttgc tagaagatgc agggatttat ttagaagaat ttggtcaaaa
    15661 cagctttatt gtacgggccc atcctacttg gtatcccaat ggagaagaag aatcgattat
    15721 tcgggagatg atcgatatgc tgctgacaac tggaagtgtg agtgtaaaaa aattccgtga
    15781 agcaacagca atcatgatga gttgcaaacg atcgattaaa gccaaccatt atttgaatga
    15841 agcacaagca cgtgtgctgc tgaaggatct ggcacgatgc gaaaatcctt tcaattgtcc
    15901 ccatggccgt ccagtattga ttcactttac caattcggat atggaaagga tgttcaaacg
    15961 aatccaagac ccgcattaag tcaaagagaa gagggaaaac atgaagattg tattagcatc
    16021 ccaatcacca agaagaaaag agttattggc tcatatcgtt tcagaattcg agattgaacc
    16081 tgctgatatc gatgaaacgc catttccaga cgaacagccc gtcgattatg ttcgtagaat
    16141 ggctgaagaa aaagcacgaa ctgtctggga acaagatgaa aaagaagacc atttagtgat
    16201 tgccagtgac acgactgttg ttctcaatca agagatcatg ggtaaaccag aagatctggc
    16261 tgaggctgaa ttcatgctga aaaaactaag cggggaaaca catactgtat atacagctgt
    16321 tgttttaaaa acaaaggaac gagaagaacg gatactagca gaagcacatg tcacttttta
    16381 tcctttgaca gacgaagaga tcaaacgcta cttggagacg ggggattatg cggataaggc
    16441 aggggcatac ggcatccaaa atgctgcgag tgtattcgtc aaagaaattt ctggagatta
    16501 ttacagtatc gtaggatttc cgattggtgc tgtcaatcag gcactgaaaa cattcattta
    16561 aacaaaaaag cggactatct gattttcgat tgaaaatcca tgatagcccg ttttttttat
    16621 tgaaaagatt acttatctac tctgactaag attttacttc agctttaccg actgcttcgc
    16681 ccgggcgaac aagtcctgat tggtcaagag aaagtcctgc aactttttca ttattggtca
    16741 aagcaacaat aatgtcagtt ttcttgccag cttgttctat ttctggcaaa tccatttcag
    16801 caatcagggt ctctggtgtg acaaggtatc cttctttcac gaatacattg aaaggaacac
    16861 cctttagttc aacagtatct aatcccatgt gaacaagtac ttccagcccc tcattagaaa
    16921 gaataccaat ggcatgtttt gtttcaaaga cactcgtcac tttaccgttt actggtgcat
    16981 agactttgcc gtttgacggt tcgacagcat aaccgtcacc catcattttt tgtgagaaaa
    17041 ctgggtcatt tacttcagtt atttccttga tggtccctgc agcgactgcg aataatgttt
    17101 cttttgttgc aactgccgta ccagttgctg aaacaggttc gaaagactgt ggcgttgctg
    17161 ttgcgccatt tgctgtttga agttgtacat cagcagcatt ttcaggaaca gcaggatcaa
    17221 tcttattcaa aattccctga cgtctaaaga tgatcgtcaa gccaaatgga atgatgacag
    17281 caatgatcat tgcgatgatg aaaggtaccc atgtttctgc ttggatagct agtattcctg
    17341 gcaaaccgcc tactccgatc gcgttagctc gaacacccat caagttagca aacatgccag
    17401 ctaatccaga gccgaccatt gcagcgacga aaggatagac gtatttcaaa ttgattccga
    17461 acatagcagg ttcagttacg cctaagtaac aagaaatcat tgctggaatc gagatttgtt
    17521 cttctttttt attcccacga tgtaagaaga tgatggctaa gactgcagag ccttgggcga
    17581 tatttgataa agcaatcatc ggccataaat tcgttgatcc gaaatctgca atcagctgca
    17641 tatcgatggc attggtcata tggtggagac cagtaatcac taaaggagca tacaggaatc
    17701 cgaatacggc actaaacaac cagctgatag aagacgtcaa tccagtattt acgatatttg
    17761 agatccagct tccgactgtc cagccgatag gacctaaaat aacgtgtgca gctaaaacag
    17821 ttggtaacaa tgaaaacaat ggaacaaaaa tcatcgagat cgactgaggg atatatttgc
    17881 ggaagaagat ttctagatac gctaacataa accctgccag catggctgga ataacttgcg
    17941 cttgataacc aatcatctgg acttgagcaa aaccaaaatc ccaaaatgga atatctgctg
    18001 cggctgtgga agctacacta taagcattta ataattgcgg agaaactaac gtaattccta
    18061 aaacgattcc taatatttgt gtagtaccca tcttttttgc aatactccaa gtgataccta
    18121 ctggaagaaa atggaaaatt gcttcacccg gtaaccacaa aaaggcattg acaccattcc
    18181 aaaacttcga gtgttcaacg attgttccac caagactttc aaactggata ccttcaagta
    18241 catttctgaa tccaaggatc aatccaccga caatgattgc aggaatcagt ggtgtaaaga
    18301 tttctgctaa aacggcaata gcacgttgaa cgggatgaag gttttgtttt gcagctgctt
    18361 ttccttgttc tttggaaacc ccttcaactc cagatactgc aacgaagtcg ttataaaaag
    18421 tagaaacatc gtttcctatg atgacttgga actgtcctgc attcgtgaac atccctttta
    18481 cgctaggtat atcttcgatc gctttttcgt ccgcttttcc tggatcattc aggacaaaac
    18541 gcatacgagt cgcacaatga ctaactgcag caatattttc ttttccgccg atatcatgta
    18601 acagcttctc ggcatctgct tgatattttg ccatatcaat aaaccccttt ctcttaactt
    18661 gtctatgcaa gttgtttctt catttactat actttttttc ggagagaatt gcaagcgttt
    18721 tattaaaaag tacgagagaa aatgatatcg ttttaaaaag cttaaaataa gcttttctta
    18781 aaaataggaa cattgaaata caaaaagagc tgtagtatag tgaagaaatg atggaagaac
    18841 gagtgaggga aaaaacatga ataagttcaa tgaaattttt ttagatttgg aacagaaaat
    18901 tttagcgaaa gaatatcctc cgcattcgct tttacccagt gagaaccaat tgatcaaaat
    18961 ttatggtgtt tcacgagaaa caattagaaa agcgctgaat cttttgacta cggaaggtta
    19021 tattcaaaaa aaacaaggaa aaggttcgat cgtactggat cggaatcgct tcgactttcc
    19081 tatttctgga ttgactagct ataaagagct acaggagacc caacgtattc caagtgaaac
    19141 gatcatccat acgttagaag aaacagaagt gacaaaagca ttgaacgaga tcactggctg
    19201 ggagatcggt gcgcctgttt ggcatttgat acgcgaaaga aaaatcaatg gcgaagtagt
    19261 tatattagac accgattatc tattaaagga aatcgttcct attttaactc cagcacaagc
    19321 acaaggatcg atctatgaat attttgaaaa tgagctttct ttgacgattg cttacgcgca
    19381 aaaggagatc acagtagaag aagtaacgga aatcatgaaa acagcgatgg atcttcacga
    19441 tgacacttat gcagtagtag tcagaagcct cgttcatctg gaagataccc gctgtttcga
    19501 gtattctgag tcggttcacc gattagataa attccgtttc gttgagtttg cccgacgccg
    19561 aaaagtgtaa atagttcaaa agaaagcaaa ttgttggcat ctgtccactt tggcgctatg
    19621 ataggatcac aaagggggca tttttaatgg ataaaccaat aagaccagaa aaagaagaac
    19681 tgaaagaaaa gttatcaccc atggcttatg cagtcacaca agaaaatgca acagaacaac
    19741 catttagcgg gaaatatgat gatttttacg aaaaggggat ctatgtagat atcgtcagcg
    19801 gtgaaccgtt attcagctct gcagaaaaat atgatgcagg ttgtggctgg ccatcattca
    19861 gcaaaccaat aacgaaaaga caagtgcgcg aaaaagccga tttttctcat ggcatgcatc
    19921 gaatagaagt tcgaagcaaa gaagcagatt ctcatctcgg acatgtgttt accgatggac
    19981 cagtagatca aggtggtcta cgttactgca tcaattctgc ctcactgaaa ttcattccat
    20041 atgaaaagat ggatgaatta ggttatgggg aattcaaatc acttgtagaa taatggaaat
    20101 acacaaagag cggtacaata cggggattta ctcgatcgtc cgctcttttt ttattcaagc
    20161 gattgctatt tgaaagaaac gctccctaga ctcctttttt cacaaggtga aatgtgctac
    20221 aataaaggga acgtatgtgt gcaaaagaaa gaggactaga atatgtatga atatctgaca
    20281 ggtgtggtta cctttatcaa cccctattac atagtagtag aaaccaatgg tatcggctac
    20341 cagatcgcac taggaaatcc ttaccgctac agtagcaaac taaatgaaaa aataaaaatt
    20401 tatgtccatc aggtaatacg tgaagatgcg catcttctgt atggatttga ttcgctagaa
    20461 gaaaagcaac tgtttttgcg attagtaagt gtttcaggaa tcggtccgaa aagtgccctt
    20521 gcaatcatgg caagcgaaga ccactccggt ttgattcaag cagtagaatc cagtgatgtc
    20581 acttatttga cgaaatttcc aggagtaggg aaaaagacag cacaacaaat gatcttggat
    20641 ctaaaaggaa aattcggtga gctgagtatc gatacacctt ttagtctatt tgatgaagca
    20701 aacacaaaag acgctacagc tctatctgaa gcaatggaag ctctctcggc tcttggttac
    20761 agtgatcgag aaatcaaacg tgtagaaaaa caattaaaag aagtagataa tcagacaacg
    20821 gatgagtatc tacgccaagc actcaagcta atgatgaaaa aataaggagg agaccaaatg
    20881 acagatgaat acttgttatc accagaatct ggcgaaaatg aactgagttt ggaaaaatct
    20941 cttcgaccac agctgctttc tcaatatatc ggacagagaa aagtcaaaca agaacttcag
    21001 atttacatcg aagctgccag aaatcgggaa gaacctttag atcatgttct gttgtacggg
    21061 cctcctggat taggaaaaac gacgatggcc atggtcattg ctaatgagat gaccgtaaat
    21121 attcgtacga cgagtggccc tgctatcgaa cgtccgggtg acttagtagc aatcttgaat
    21181 gaactggaag caggggatgt cctgtttatc gatgagatcc atcgattacc tagagtggta
    21241 gaagagatgc tttattcagc tatggaagat ttctatgtag atatcatggt aggacaaggg
    21301 ccaaccgcac atccggttca tttccctctt cctcccttta ctttgattgg cgcgacgaca
    21361 cgggcaggta tgctttctgc acctttacga gatcgatttg gcatcatttc tcatatggaa
    21421 tattatgacg aacaggatct gcaggagatc gttttacgtt cttcggatat ttttcaaaca
    21481 gagatcattg aagaaggggc attggaaatt gctcgccgat cacgaggaac gcctagaatc
    21541 gctaatcgct tgctcaaacg ggttcgtgat tttgcgcaag tccaaggaga cgggaaaatc
    21601 gatcgtccta tagcggatca ggcacttact ttgctacagg tcgatcaggc tggattggat
    21661 tatgttgacc agaaattgtt gcgaacaatg atcgagttat atggcggcgg accagtaggg
    21721 ttaagtacgc tttcagtaaa cataggagaa gagcgtgaga cggtagaaga tatgtatgaa
    21781 ccgtatctga tccaaaaagg atttttaaag cgtacaccta gagggcgaat tgctactgct
    21841 tatgcctatg aacattttgg ttacgactat catatatgat ttttgctttt agattggagg
    21901 aaaatgaatg agtgatacaa cacgtacgaa acaattgatc aaaaacgtat tgattgattt
    21961 gtgccaaacg caatcttttc gaaaaatcag cgtccaaaaa atcgcaaatg aagcaaaaat
    22021 caatcgacaa acattttatt atcattttac agataaatac gatttgcttc gttgggtcta
    22081 ttgtgaggat gcattgcatt atttagatcc acaatgtctt tcacttgata attgggaaga
    22141 gcaagcattg aaaatgctga aagcaattgc tgagaagaaa gaattttatg caaatactgt
    22201 gctttctgac ccagaaattt tacaaaaaga gttttctcaa ctgatccaaa aatcatttat
    22261 caagattttt gaacaaatgg atgaagaaag acaactttct gcaagagaca aactatttta
    22321 tgctcgtttt ttttcttacg gttgcagtgg tgtattagtc aattggatca cgaatgaata
    22381 tgaagaaaca ccgatggaaa tcgctatgca gcttttccgt ttagccaagg atacggaatt
    22441 atattcttat cgtctttatg caaaagaaga gttggaagaa cagtaataga aaaatttttt
    22501 gttggaaaag caataatcgc taaaaggaga tggggaaatg acaaaaattt tatttgtttg
    22561 tttgggaaat atttgccgtt caccgatggc agaaggcttg ctgagaaaac gaatagcaat
    22621 agaaggaagg gaagcagaat tttttgtgga ttctgctgct acaagcacgt atgaagttgg
    22681 aaagacaccg caccctggaa cgaaaaaaat attaaaccaa gaaaaagtag atatgacgaa
    22741 tatggttgct cggcaaatca caccccacga ttttgaaact tttgattgga tcattggcat
    22801 ggatcaagaa aatgtagaag aactgaaacg aagagcacca cgctcagcgc aggggaaaat
    22861 ccatttgttt ttaagtagca ttcctggaaa agaaaaagaa aatgttcccg acccatacta
    22921 taccaataac tttgatgaga catatcactt gatcacagaa ggcctgaatc attggtggaa
    22981 tatttggatt gacgaaaata aaataacaaa caatttgtaa agttgacgct ttctttttaa
    23041 ggcgatgtta gagcatttcc ttgttttttt gtaaaatgtt aggtaaaata aaattaatta
    23101 agtaacactt tcttagctaa aggaggagtg cattcgatga acgaagagac agtatcgcca
    23161 atgaagaagc ttacgaagtt agttactcat acttcgtatc aactttttga ttcttttgta
    23221 aatgacactg aagaacatgc taagaatgta cgattgcaag gaaaatttat tcttgagctg
    23281 caaaaagctg ctactgaaca tagtctagtt atcttacaag taagagcgaa tcgtttgagt
    23341 agcaagtatg aaacgatctc aggctgggtg gcgacaaaaa cggtcgaaaa agaccgagtg
    23401 atgatccgcc tacaaaacga agagcagcag atccggatgg ttcctgtaga acaaattgaa
    23461 aaaataacaa tcctttcacc agcaggggaa caggaacgat tatcaaaata atttatacca
    23521 gatagaaaag cacgtatgag cttgtaccat caatcattac taatcaaaaa taaccgaatg
    23581 ctttaagctg atatcagtaa aacggaacgt tttaggatga gtatcacagc atgacagcat
    23641 tgggttgatt agttgaatcg attggatggt acaagttttt ttgataaaaa aaggtcctgc
    23701 tagccgggga gctagcagga taaggagtta aaaatgaaaa agtgttgtta gggttgtttg
    23761 ttggtatgct tatataatag tcactagttg tgaatatttt gtgacgaaag ttttcgaaag
    23821 ttgttaagtt tttttgcgaa aactattttt atatcatata tatgtctaaa atctatatta
    23881 taaaagaaat gttgtttgat cagcttctct tcggtattag ttcaaaacaa aacggcaaag
    23941 tatatggagc tactttgccg ttttgtttct ctaatactca ggtcagttta tagacgctca
    24001 ataaacggtg ttcaaaagcc agtttctcgg tattaagtca aatttatgca aaaatgtgag
    24061 aagccatttt caaaaaatat ttcttaatac tcgaaactga gcggcttttt cacgacctct
    24121 caataaacag tgttcaagag acagcctatc ggcaataagg ctgaacgtct ctttcacaac
    24181 ctcttttatc aatctgctac ttcttctttc ttagcgaaac tccaaatcag tccgataaca
    24241 aaaccgataa ctgctggtac gatccacccc atccccaatt tgaaaaacgg caagtagctt
    24301 tccgcaacat ataaaagatt ttgaacaata ggtgtttgtt tgatagtttc tgggcaagcg
    24361 ttcaacccat caaaaatcga agcaatcaat gtaaaataag tagtcattcg ataaacagcc
    24421 gtacgctgct taaacaaagg accaactaac actagtaaaa tcagtgtcat tgctaatgga
    24481 tagatgaaca tcaaaacagg caacgaaaat tgaatgatat tcgtcaagcc tacgtttgcc
    24541 gctaaacaag gaaggatact agcaagtgca acaaagaatg cgtaatttct ttgcggaaac
    24601 aaatctgtga atgtttctgc aaaagctgta atcaaaccaa taccggtctt caagcaagct
    24661 aatataacga taaatgctaa taagatactg ccataagtac ctaaataatg atcagcaatc
    24721 tgagccagcg tgatcccgcc attttcactt agagcaaagc tacctaagct catagcacct
    24781 aaataagcga gcaaagtata aatgattccc atcaatataa tgctgatcgc accagatttg
    24841 atcgtgtctt tagcgatttc agcaggtttt gttacaccca tgttttggat tgttgtgaca
    24901 atgatgatcc caaatgctaa agcagcaagc gcatctaatg tgttatatcc ttgagtaaac
    24961 cctgtgaaaa aagcatgctc ttgataattt ggctgaatag gcgcttgatt tacagaacct
    25021 agtggattca aaaaagcaag gagaagcaaa gcacctaata aaaccaaaaa tgcaggattc
    25081 aggaactttc caacataatc taatatcttt gtcggttttc ttgaaaacca ccaagccagc
    25141 acaaaaaata caatactgaa aattgctaga tatagcgtct gtctgctagg atcgataaat
    25201 ggtgctaaac caatctcgaa agatgtggtt gcaaggcgag gtaaagcaaa aaacggtccg
    25261 ataactaagt aaagcaagat ggtaaaaacc atcgcatatg tttgatttat ccgttttgct
    25321 aattcatata cacctgagct tttcgataca ccaatggcaa tcacccctaa gaagggaaga
    25381 ccgataccgg taaccaagaa acctagattc gcccaaaagg tagcagcgcc tgcttcttga
    25441 cccaaatgaa cgggaaagat aagatttcca gcaccaaaaa atagaccgaa aagcatggag
    25501 cctataaaaa gatagtcttt aaatgataat ttttttgtca tacataactc ctttacggtt
    25561 tttttaaaag taacaaaatt tcgaaaaata tgcaacaatt ttcagaaaat ttcctatata
    25621 aaacgacggt tatttaataa cgtaagtgat aaaataaaag cgctgaatca tctgaggagg
    25681 aatcatcgtg acaaagtcga gattagaagc atttactgat ggagtggtag ccattgtttt
    25741 gagagttctt gtattagaga tcaagatccc taatacatct agctttcatt ctttatgggt
    25801 catccgaaat acattattag cttataccat cagctttata tttgttgcgg tgatctgggt
    25861 gaaccatcat cgtatatttc agatggcaga acgaattaat taccgagtgg tctggtcgaa
    25921 tatctttttg ctcttttggc tgactttatg tccttctgtt actagttggg tcgggcgtaa
    25981 ccctgaagct ttttggcctg agatggctta tgtcttagta tacacgatgt ggagtttttc
    26041 ttttggtatc ttgatgaggc aaatcatgaa agcaaataaa ccagattccc atgtcgtgag
    26101 agttttgtca aaggaccgtc gaagtcttat ctccatgatg attaacttat gcttgattgc
    26161 cggtgtcttt tttgtaccgt tgatcgggtt attcggacgt ttttttgtat ctggtatttg
    26221 gattttttcc tataaaaaag cagatgccta ttatcagcgg ttgtttccgg ggaaatagaa
    26281 aagaggctgg gacagaagct tttaactcca agaaataagc cgaaatttca caaaaattta
    26341 agaagcaatt ttcgtaaatt ccttcttatt tctcgaagct gaccacttct gtcacaacta
    26401 ctttcttact tcttacgttc atatttcata tgatagatta gtaatagaag caagaaccac
    26461 acaggtgtta gtaataaagc gattctcgta tcttttccta ggaacaagac gacacacaca
    26521 aaggccatgt aaagaaatac cagataatta ctaaatgggt acaacggcat tttaaatgaa
    26581 tgagcttttt tgccgaggat acttttacga tatttcatgt gcgtgtagac aagcatactc
    26641 cagataaaca agaaacaagt agtggcaata ctgcttacta gtgtgaatac ttcactaggc
    26701 atcacgtaat tcaagataac agaaatgaaa atgacgatag tagaaaatgt caaagcattc
    26761 cctggcacat gatgtgttgt taactttttg aattttttag gggcactgcc ttcttgcgct
    26821 aaagaacgaa gcatacgtcc tgtactatat attgcactgt tgcaggcaga agctgctgca
    26881 cttaatacga ctaaattgat caaggaagca gcaatcgtga tcccaatttc cgaaaatact
    26941 tctacaaatg gactgttatc tggattcaag ctgttccatg gatagattgc cataatgaca
    27001 aaaagagatc ctaagtaaaa taagatgatc ctgataggaa tattattgat agcttccggc
    27061 aacacttttt caggattttc tgtttctcca gcgactaatc caactaattc tatcccagca
    27121 aaagcaaagg ttaccatttg gaaagctaag ataaatcctt ttgcaccagt tggaaagaat
    27181 ccgccatgag accatagatt cgtgatactg gctgtgccaa tatctgtcgt atagtgggtg
    27241 aggatcatat aagctcctac gaggataaag gcaatgatcg ctacaacttt gatcaatgca
    27301 aaccaaaact ctaactcacc aaacaatgag acagccacca tattcaagca aagaagaaga
    27361 cctaatgcaa tcagttcagg aagccactga ggaacaccag gcgcccagta gcgtacatac
    27421 attccgatgg ctgttaaatc ggccattgca atcgataccc agcagaacca atacgtccag
    27481 ccagtgatga aagccgcttt tttgccaaga tattctgcaa caaaatccag aaaagaatgg
    27541 ttattggtgt ttgataacag aagttcgcct aacgcacgca taatgaaaaa acagatgcat
    27601 ccagtaataa gataggcgag caatatcgaa gggccagcta gctggataga ctttccggaa
    27661 cctaaaaaca accccgttcc aatcgctccg ccaatagaaa tcagttggac atgtctattt
    27721 ttcagtccac gctgcagttc ttgctcttca ttcattttta aatcatccta actaaaaaag
    27781 tttaattact tccatattaa aagagttttc tgaaaaacac aactaagatt ccaaaatttt
    27841 cagaaattta ccttttatga gtaattcata aaaaagaact gcggtaaaca ccgcagctct
    27901 ttgtcccaat cagctattga tcctaagcat ttaaaatacg tgaaaggaat tcttttgtac
    27961 gttcttcttt cggatggaca aagatatctt ctggtgtacc ttcttctgca atcacacctt
    28021 tatccataaa aatgacacgg tcagatacat cttttgcaaa ttccatctca tgcgtcacga
    28081 taagcattgt caagccagta tgtgctaagt ctttgatcgt attaagcact tcgccaacca
    28141 tttcagggtc taacgccgaa gtaggttcgt cgaatagcaa tacatctgga ttcattgata
    28201 atgcccgagc aattgcgaca cgctgtttct gtccaccaga taattgtgct ggtttggctt
    28261 cgatataacg atccatacca actttttcca gattttcgat tgctactttt ttggcagttt
    28321 ctttatctcg tttcaggaca gttgtttgac cagacataca gttttccaag acattcatat
    28381 tgttgaacag gttgaaggat tggaaaacca tacctagatt cgttcgatat ttaggtaaat
    28441 tatatttagg agctaataca ttttctccat tataaatgat ctcgccgcct gttggttttt
    28501 ccagtaaatt gatacagcgc aagaaagtag atttaccaga accggaagaa ccgatgatcg
    28561 tcacaacttc acctttattg actgttacgc tgatatcttt caatacttca ttttcaccga
    28621 agctttttct tagatgtttg atttcaataa ttttttcatt catgattctt cctccttatt
    28681 cctgcaaatt tgaattgtcg atttcttcaa gcttggtata agctgaagga ccatcgattt
    28741 tcttttctac cgcccgcagg attctggtga tcgtaaaggt catgactaag tagatgatcc
    28801 cgacgatcgt aaatgtttgg aagaattgga aattcgcacc ggaagcagag tttccttgga
    28861 agaacaaatc agctacgccg attacactta aaactgctgt atctttgata ttgataacaa
    28921 actcatttcc tgttgctggc aagatattcc gtaaaacttg tggaataaca acttttctca
    28981 tcgtttggcc atgggtcata ccaatggctt gcgcagcttc gaactgccct tcatctactg
    29041 caaaaatccc cccacgaacg atctctgtca tgtaagctcc agtattgaga gagacaataa
    29101 acaaagcggc aatcgttcgg ttcaatgaaa tgccaaaagc gagtgccaga ccgtagaaga
    29161 tgaccattgc ttgtaccatc atcggtgttc cgcggaatac ttcgacatag atagaaagaa
    29221 gtgcatttcc gattttttgg aagaagcgag tcagtgcatt tcctgattca ggtaccgaac
    29281 ggaagacacc aatcagtaat ccaagtgtag taccgacaac tgtcccgatc aatgcgatga
    29341 acaaggtaag tccagcacct cgtaagaaca tattgccgta ttgtttccaa atcgtagtga
    29401 aatcagaaat gatgccaggt ttttcttcac tatcagttgc agcaggctga tctttgactg
    29461 cttggtccat aattttggtt cgttcatcgt tagagatgcc agaaagaatc tggtttactt
    29521 tttggatatc cgggtcgcct ttacgcatac caacagaaat ctgaacatct tccgggtttg
    29581 tctggaagcc atctgcaccg ctgaattcaa gcatttccaa gtctttgttc acactagttg
    29641 ccgttacacc ttccggacgt tcgctgacat aaccatcgat cattccagaa gctaaagctg
    29701 ttctcattgc tgagaaatta tccattgctt gttgtttctg cacatctggt atctgatcga
    29761 tcacagtata gtggaatgta tttaactgag cagtaatctt tgctccagaa agatctgcta
    29821 aactttttgc ttttgcatat ttgctatctt tttgaactac tactactaat tgtgattcgt
    29881 aataaggatc ggtaaaatca atttcttttc gtcgttcagc agtagggctc attccggcga
    29941 tgatcgcgtc gatcttgcct gattgaaggg caggagccag accatcccat ttcgtttgga
    30001 cgatgactaa ttttttccct aaaccatctg ctactttttt agcgatttga acatcataac
    30061 cgccggcgta actattttgg ccttgaattg gcaaggcatt attctcatct gtttgttgag
    30121 accagttgaa gggtgcatac ccagcctcca tacctacgcg aaactcatcg ctcggtgttt
    30181 tttcatctgc atttgccaga gatcccacac tgaatagtga gaagacaaaa gcaaatagta
    30241 cggcaactga aaccatattt tttttcattt ttttctccct ttctgattat atgatacacg
    30301 agcggtctag atgaaatgcg gtaaagcttt atctgaaaaa ataaaaagcg accgatttat
    30361 agatataaaa aggccgctaa aattccataa ggtgataaac ctctcacaaa acatagcgca
    30421 acttagcatc actgctaaga cagtccgcaa gctcttaact tgcgtcccaa catacactcc
    30481 aagcaaaaaa gtgcacattt cggcgatcct ccctattcct gcttctccat gtttgcttca
    30541 ctccacaggg ttaatgattc tcgcgacctc tacctcattg attgaggcat ctcgtattca
    30601 gttatttata caaaaaaagt ttacgatact cgagaggctt tgtcaatcta taactgctgt
    30661 tttttgaaaa aatactgata aatatagaaa tctttacttt taccgaaaaa acaatcaaaa
    30721 tgtgaatcat ctatccattg caaacgatag tataattata cacaaaaatg tatgtaatac
    30781 aataaaaaaa gaactagaac agaaaatttc ctgtgtccag ttccatctcg atcatttaag
    30841 ctgccgcttt ctttggctca cgtcctagga tcgcttgcaa aagaacaacg acgccataaa
    30901 tggctaatat tagataaatc aaacttgagt attgggtgat tccccagccc catgttcgat
    30961 atacggctaa tgtaatggct aaaacaattg cggcaatcac gttgaataaa gcaaaagccc
    31021 aaagatttcc attttctttg cgtacaagat aaaaaacaga gaaataaacg cttaacgcta
    31081 accaggcgat acaagccaga ataacgcccc aataaataaa gaatggtaac atatcgattc
    31141 acctcacttt tatacagcag tattgtaaca cgttttcatt cttttgtcag tgaacattgt
    31201 gataaattgt tcaaatgccc ataacacttt tttattccca tttttctgac ttttcaacaa
    31261 taaatttgtt cgagtatggg ctataatgga aagtgaggtg acaaaacatg aaacaattaa
    31321 cagtagacga agcagcaaaa gagatattag cttatcagca aattacattt ttgaccggtg
    31381 caggggtatc cacaccttct ggagtgccag actatcgatc tttgtcagga atctaccacg
    31441 ggatggagca gccggaatac ttgctgagtc atcaagcaat ggtgaatgaa ccggataaat
    31501 tctatcaatt tgtcaaaaag atttatcatc ctgaagcaaa acccaatatc attcatttgg
    31561 aaatggcaca tctagcgaaa gaaaaaaatg tttgggttgt ttcccaaaac atcgacggtt
    31621 tgcacgcaaa ggctaaaagc ccgcaactcg tcaattttca tggaagtttg tatcaatgtc
    31681 attgtcgaaa atgtcaacaa acggtagact ggaaagaata tcttcacagc gacaaacatc
    31741 aagcatgcgg aggacaaata cgcccagaca tcgtgttata tggtgaaggg tttcaagatg
    31801 gagtcatgga gcaggcggct tatgccgtca gccaagcaga gctgatcgtc attgttggaa
    31861 cgagttttca agttcatccg ttttgtgatc tggtacagtt tcgccagccg tcagccaaaa
    31921 tcttagtaat caatcaaacg cctgtttatt tagcggagcc ttatacgttt attcaagaag
    31981 acggagcggt tgttttcaaa aaaatacaag aattaggagc agattatgac tgaattcaaa
    32041 accgaaaaag aaaaaatgat tgcaggcgag ctttattttg ccaatgatcc tgagctggtt
    32101 gccgaccgta tgtttgcaag aagtcaaagc caaatcatca accaagcaga atcagcggaa
    32161 ctgcgatccc aattgttgaa agagactttt ggccgtacag ggaaaaaaat ctatatggag
    32221 ccagttatca attttgatta cggatataat atatttgttg gggagaattt ttatgcaaat
    32281 ttcaattgta catttttaga tgtcagcacg attgaaatcg gtgataactg catgttcgct
    32341 ccgaatgtcc agctttacac ggcgacgcat ccactacatc cagtgaaacg taacagcggt
    32401 ctggagtacg caaaacccat taaaatcggt aataatgttt ggttaggcgg aggagttatc
    32461 gtcacgccgg gtgtcactct aggggacaac gtagtagtcg gcgcaggttc ggttgtgacc
    32521 aaatcttttc ccgacaatgt agtgattgca ggaaatcctg ctcgtatcat caagacagta
    32581 gaggaagaac taacagaaga gtctcttgaa acattacgtc ataagatcga tatgatcgat
    32641 cgagagttga ttgctttatt agaaaaaaga atggatacgg taactaaaat aggacaagtg
    32701 aaaaaagaag aaaaccaagc agtttatgat gcaaaaagag agcagcaagt attggataaa
    32761 gttgttagtc tgctgaaaaa taagggatat aaggaaacaa taacagatac gtatgttgat
    32821 ttgatgaaac actcgcgcga ataccaaaac aaaatgaagg aggaataagt gtgatcgaag
    32881 gagagacacg gcgaaaacaa atcatgcaaa ccttggcaaa tacagaaaaa ccagtgagtg
    32941 ctagcaagtt tgcgaaaact tttggagtca gccgtcagat cattgtaggc gatattgctt
    33001 tactacgagc tgcaggtaaa agtatcgtgg caacagcaag aggttatatc ctcgaaacag
    33061 aagaaaccaa tactgggcac atcagtaaaa tcgctgtcca gcatggaaaa gatcaaacag
    33121 aagaagaact gagactaatc gttgaaaatg gtggtgaaat cattgatgta attgtggaac
    33181 atccccttta cggtgagtta gcaggaactt tgcacatcaa aacgccacaa gatatcgatt
    33241 cctttatgag acgttatcaa aaaagtaatg ctactttgtt atccgaatta acaggcggca
    33301 tccatctgca tacgatccgc tacccagaaa agcatatgct gaaaaacatc aaacaaaaac
    33361 tagctgaagc aggaatcctc tacgaaggat aacatcgtag ctgctacttt ttatcctaga
    33421 aactattcta tcatctctga gataaacacc catatggaag aaataagaaa aaataagaaa
    33481 agatgcgtat ccaatacaca gaattttttg gaattgcgat ttctagatgt ctatctaaat
    33541 ttcgattagt ggagaaacat aaaaaaggga agtgcagctt ttgagcactc ccctttttta
    33601 taaagctttc ttgtagcata gtatcgaagg aacctgccaa ttctctactc gatcaccaat
    33661 acgccttctt ttagtgcaaa tggattttga tcgttgatgt ggtcatagaa catcacaccg
    33721 ttgatatggt cgatttcatg ttgaacgacg atcgattcat aattcttcaa acgaatcttg
    33781 tgtttttcac cattcatatc ataataagac acagtgattt tggcatggcg aacaacatat
    33841 cctggtactt ctcgatcaac agataaacag ccttcacctt cccctaaaca agcatcttga
    33901 acagaatggc tcaaaatttt aggattatac ataacagtac ttagagaagg tccatctgcc
    33961 tctgggtcag gacttggtac gtgaacagca atgattcttt tagaaatatc taattgagga
    34021 gcagctaagc caacaccgcc tcgtaagtgt agttcttcag ctttgattgg atcttggctg
    34081 ttttttaaga actcaagcat ctcttttcct aaagagatat cttcttcgct taatggaaga
    34141 gaaacttctt ttgcaacttc gcgtaaggtc ggatttcctt cacgaatgat atcatccatt
    34201 gtaatcatgg aatatgtacc cctttcttaa aagactgtgt ttcaagtcta ttttcgcatt
    34261 atagtttacc acaaaaatgg aaaagtagta gtaagattgt ttgaaaacta ccttttctta
    34321 atgattaact acttgatttt caacccggtt tcaggtaaag tatagctgtg tgctctaggc
    34381 acatgacctg ccacttggtt aagcgaatca ccaacgtttt actcagtcgc aggggaataa
    34441 tcgaaagagg tgaaagaaat ggcaatttca aaagaacgca agaatgaaat catcaacgaa
    34501 tacgctcgcc atgaagggga tactggttct ccagaagtac aaatcgctgt attaactgaa
    34561 gaaatcaacc acttgaatga acatgcacgc gtgcacaaaa aagaccatca ttcataccgc
    34621 ggcctaatga aaaaagttgg tcaccgccgt aacttgttag cttacttacg taaaactgac
    34681 gttcaacgtt accgcgaatt gatcaaacgt ttaggcttgc gtcgttaatt ttagtcaaaa
    34741 agagtgggat tcacatgaat ctcacttttt ttactcgtat atcaattaag taaaattccg
    34801 tgatcaagct agatggactc ctactaacca aatgaaagct gctcaaaaga cggctttcgg
    34861 cagttttcat ttgtttagta gcgtcttgct ttcacgagaa ggaaaaggag aagttatgtc
    34921 agaaaaacaa gtattcaaaa cgacatgggg cggccgtccc ttacaaatcg aagtcggtca
    34981 gctagcaaaa caagcaaacg gagccgtttt agtccgttat ggagatacag tagtcttaag
    35041 tgcagctgtg gcctctaaag aagcaaaaga tacagacttt ttcccattaa cgatcaatta
    35101 tgaagaaaaa atgtatgcag cagggaaaat ccctggaggt ttcatcaaac gagaaggccg
    35161 tccaagtacg gaagcaacat tgactgcccg tttgatcgac cgtccaattc gcccgatgtt
    35221 tgcagaaggc ttccgtaatg aagtccaagt aacgaacatc gtgatgagtg tagaaacaga
    35281 ctgctcgcca gctatggcag caatgctagg ttcttcttta gcactatcaa tctcagatat
    35341 cccatttgac ggcccaatcg caggcgtaga agttggtcgt gtaaatggcg agtacgtctt
    35401 gaatccaaca gtagaacaag cagaacaaac agatatcgaa ttgactgttg ccggaacgaa
    35461 acaagccatc aatatggttg aaagcggcgc gaaagaagtt tcagaagaag acatgcttgg
    35521 tgcattgctg tttggttttg acgctatcaa agagttagtt gctttccaag aagaaatcgt
    35581 tcaagcagta gggaaagaaa aaatggaagt gactttactg caagttgatg aagtattgaa
    35641 aaaagaaatc tttgatgctt cttacgctac aatgaaagca gcagtaatga ctgaagaaaa
    35701 acttgctcgc gaagataata tcgagcaggt gaagatcgat atccgcgaag cttatgctga
    35761 gaaatttgca ggtcatgaag atgaagatca cttgttgaaa gaagttaaac aaatcacaga
    35821 agatcttgaa aaagatgtcg tacgtgaatt gatcaccatc gataagatcc gtcctgacgg
    35881 gcgtaaattg gatgaaatcc gtccattgtc atcagaggtc agcttattgc cacgtgtaca
    35941 tggatcaggt ttgttcacac gaggacaaac acaagcttta tcagcttgta cactcgcacc
    36001 tctaggagag caccaaatca ttgatggttt aggggtggaa gtcagcaaac gattcatcca
    36061 ccactacaat tttcctcaat tttctgttgg ttctacagga cgtgcaggct ctccagggcg
    36121 tcgggaaatc ggacatggcg cattaggtga acgtgcgtta gcacaagtaa tcccttcaga
    36181 agaagaattt ccttatacga tccgtttagt agcagaagta ttggaatcaa atggttcttc
    36241 ttcccaagca agtatctgtg ctggcacatt agcattgatg gatgcaggtg taccaatcaa
    36301 agcgccagtc gccggtattg cgatgggact tgtttctgat ggtgaaaact atacgatcct
    36361 aactgatatc caagggctgg aagatcatct tggcgatatg gactttaaag ttgccggtac
    36421 aaaagatggt atcactgctt tacagatgga tatcaagatt caaggaatca cagaacaaat
    36481 cctaactgaa gcattaactc aagcaaaaca agcacgtatg gaaatcttag aagaattgac
    36541 ttcaacgatt gctgctccac gtgaagaatt aagccaatat gcaccaaaaa tcgaaatgat
    36601 ccagatcgaa cctgctaaaa tcaaagatgt tatcggtaaa ggcggcgata cgatcaacgg
    36661 aatcatcgat gaaactggtg tgaaaatcga tatcgatcaa gatggaaaag taagtattgc
    36721 ttcagctgat gcagaaatga tcaaaaaagc tatcaagatc atcgaagatt tgaccaaaga
    36781 agtcaaagtt ggtgaagttt atctagggaa agttgtccgt atcgaaaaat tcggtgcatt
    36841 cgtcaacttg atcaaaggaa aagatggact tgtccatatt tcccaattag caaacgatcg
    36901 tgtcaataaa gtcgaagatg ttgttaaact aggtgatgag atccttgtga aagtaactga
    36961 aatcgataaa caaggacgcg taaatctgtc aagaaaagca atgttgaacg aagatggttc
    37021 aacgaaaaat gaagaaaaat aatttaattc ataggaataa tgtacttgtg atcgtgaagg
    37081 tgacaggggg acaataatta ttcgaaaaaa ggggactgtg acaaaagccg tgtcacagtc
    37141 cttttttttc gaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag
    37201 ttaaaaacat taggagctgt ttttatttgg ctgttcttat tacttgatgc agaacagctt
    37261 ttttacaacc tctccaataa acgatgttca atcagctgtc cctcgatatt agctcaaaaa
    37321 acggcaaaat atgaggaact atttttccgt ttgtttctct aatactcagg tcaaaccgct
    37381 gatttcacaa cctctgattc acggtgttcc agaagcagct tctacggaaa taagctgaac
    37441 acttttgtta caacttcttt ttttctggag tttcttggcg catatttttg gagtccttct
    37501 gaataaagcg taaaataaaa gtgagaaata tggataaagg agggaaagga gatgctgaat
    37561 tttttatggt cgttatttat cggcggtata ttaggtttga tagctggcgc aattttagga
    37621 aaggaagtcc cgggaggcgt atctggaaat atcattatcg gttttttagg tagttggctc
    37681 ggcgaatttt tactaggacc actgggaccg gaactcggcg gtttttattt gataccagca
    37741 ttattgggtg caattttttg ccttgctctt tattcatttg tggcaagacg tatcagagaa
    37801 cgtccaaaga aagaataatt ttattcaaat aagttgacac ttcagtgtgt tacttggata
    37861 attagaagca atttaggaaa gcgggtgtca tggataagaa tatcatctat cattcaagct
    37921 tacctaaagg atatccatat aacaagaaat gagggaaaaa cgtggcaaca acgcacaata
    37981 ccaaaaagat atcaatggct ggcctgcttg tagcgatggg agtcgtctac ggagacatcg
    38041 ggacaagtcc gctttacgtt atgaaatcga ttgttgaaga taatggcgga ttgtcaggaa
    38101 tcaatcctga ttttgttatc ggatcagtct cattgatttt ttggacattg actctactga
    38161 caacaatcaa atatgtcgtg attgcattga atgcagataa ccatggtgaa ggtggaattt
    38221 tctcactcta cacacttgtc cgaaaaggtg ggaaatattt gatcattcct gcaatgatcg
    38281 gaggagctgc cttactagca gatggggtat tgacccctgc tgtgacggta acgactgcga
    38341 ttgaaggctt gcgaggaatt ccgcagtttt ttgaccggtt cggtaataac cagaacgtga
    38401 tcgtcattat cactttagtt attatttttg ttttattcat ggtccaacgc tttggtacag
    38461 atattgtcgg aaaagcattc ggaccaatca tgttcgcttg gtttactttt ttaggcgtaa
    38521 tgggattaat gaacttcagt caagactgga cagttatccg tgcactgaat ccttattatg
    38581 ctatccagct gctttttagt gcagataaca aattaggctt gttcattctt ggaaatattt
    38641 tcctggctac gacaggtgca gaggcgcttt attccgatct tggacatgtc ggcaaacgaa
    38701 atattcgtct gagctggcct tacgtcaaaa tttgtttggt tatcaattat tttgggcagg
    38761 ctgcgtggtt gttgaatgtt tatcaaaacc ctgaagcaca gcaaatcaag aacctgaatc
    38821 cattcttcca aatgatgcct caaagttgga tcgtgatcgg cgttgctttt gcaacagtcg
    38881 ctgcagtcat tgcttcgcaa gcattgatta caggttcgtt tacgctagtt tcagaagcaa
    38941 tcaagttgaa actgctgcct cggttaaaga tcatgtatcc tgggaacagt atcgggcaaa
    39001 tgtatatccc agcagtcaat ctgattttat ggatcgcctg ttctctagtg gttgtcacat
    39061 tccgaacgtc tcatcatatg gaagctgctt acggtctatc gatcactgtg acgatgttga
    39121 tgacaacagc actgctttac ttttatctta tccaaaatgg gcattctcgt tggcttgcat
    39181 atttagttac ctttttcttc ggtgcgatag aagtcgtttt ctttatctca agtgttgtca
    39241 aattcttccg aggcggtttt gtagccgttc tgattggttt gatcatctta gtcgtgatgt
    39301 ttatttggga acaagggaac attattcgcg aatcgtcaac cgaggatgtg tctttgagag
    39361 attatatccc gcagcttaga gaattacgtg atgatacttc tttaccaatc tatcagacaa
    39421 atgtggtctt cttggttcct gatatggctg aagataaagt tggccgacag ttcatctatt
    39481 cgattttaga taaacggcct aaaagagcac gagtctattg gtttgttcat gtggaagtga
    39541 cggatgagcc atatacgaaa gaatatcaag tagatatgat ggacactgat tttattgtcc
    39601 aagtgaatct gttcttaggt ttcagggtcc aacaggaaat caacgtatat gttcgccaag
    39661 tcatccatga tttgatgaaa caaggccgtt tgccaaaaca gccacaaaga tactctctga
    39721 caccagggcg agaagttggc gatttccaat ttgtcctgat tgatgaagta gtttccaatg
    39781 tgacaactct aggaaaatgg caacgtcaaa tcatgcaggc aaaactggca atcaaaaaaa
    39841 tcgctacctc gccagaaaca tggtttgggc tagagtacag cgaagtaaaa catgaaactg
    39901 ttccgcttat cattggaaat actcggaaaa catggttgaa agagcggttg tgaaagtagc
    39961 gctttgacct gaactaatgt cgaatgtcag ctacttgaac accgtttatc agaggtcatg
    40021 aaaaagctgt actgcaacaa gcagtaagaa cgagcagata aaaacagctt ctcatgtttt
    40081 tcatctgttt gggcttaatg ccgtagatgc aagcttttga ataccgtttt tatcagaggt
    40141 catgaaaaag ctgtttagca acaagtaacg caatgatttt gaagtgataa ggagatgtgg
    40201 ctgaaaaatg ccgcatctcc ttttttattc ctaaatatga atacgcatta ttttcaatct
    40261 ttttgtagaa aaagggtaca atagaaaaag agaaaggcgg gagaatatgg ttatcaattt
    40321 cattatttta tttttgatga ttgcaattac ttcatttttt gtagcaagtg aatttgcttt
    40381 agtgaaaatc agacgatcaa gattggaaca actagaaaag gaaaatgtaa agaacgccaa
    40441 gctagctctt catgttacac accatttaga taactattta tcagctagtc aattaggaat
    40501 tacgctaacc ggtttgatca tcgggtgggt cggtgaagga tctgtcgcgg ctttactaga
    40561 accagtgatc ggtaaactac cttttagttc ggctattagc agtacaatct ctgtggcgct
    40621 gggatttatt ttagttacgt atatcgatgt ggttattggc gaactgcttc ctaagagcta
    40681 tagtatcgtc aatacggaga aggtcgtctt gttcgtagtt aaaccacttc attattttta
    40741 taaagtaatg tttcctttta tttgggtatt gaatcattca gctgcagggc tagggaagct
    40801 attaggtgtg cgtctcgtat ctgaaggaga agagacattg tctcaagaag agctgacatt
    40861 agtcgcattg aattcttatg aaaaaggaga gttgaccaaa gaagaatatt attatttgga
    40921 aaacgtgttt gaatttgatg ataccttggc aaaagatata caagtagacc gtacgtccat
    40981 gcaagtattc gaagcttcag aaaccgtcaa agaagcgata aaagcttcga ttgaacaagg
    41041 acatactcgc tatccggtta tcttagaatc aaaagacaat gttttaggtt atgtcacctt
    41101 gccagatttg atcaagcaat cttataaaga tgaccagctg acagtagaac agttgattga
    41161 agagccgatc gtaacaactg aaacgatccc tataaaaaaa ttattgacga tcatgcgaaa
    41221 aaagggtaag catattgcta tcttaaaaga tgaatacgga gggacaagcg gcttagtgac
    41281 gattgaagat attttagaag aaatcgtcgg ggaaatccga gatgagacag atttggacga
    41341 agcattgata gcggaacagt cagatggctc ttatatcatc tccggcaaac taacattaga
    41401 tgatttccag cgttattttc atgtagagat tccagagttt gaagaaacga attttactac
    41461 acttgcgggc tttgcttcta gccgatataa agaaataaaa gcaggaacaa tcattgagat
    41521 tgcatcattc cgtttcacgg tattagaata ccagcatgca catatcgatt atttcaaagt
    41581 agagtccacg gaaagaaaaa cagaataaaa gaaaaaaggc tgtgacattt tttgtcacag
    41641 cctttttgtt atctaaaaaa cctgttttcg gtaaacgaag aagatatttt caataaaagt
    41701 tttcattttt agccgcaacg atttctttta atcaaggcta tcttgcttct gcatgttcta
    41761 atgtgaaatg ttcctcttca cccatgtgtt tcaattgttt catcgaacgc atataagagt
    41821 aaagcaacac ggcaacagaa ccgatccaag ctaaaggaga agctgctgct gctcctgggt
    41881 atccccacat tcctgtaaga acgatagctg caaaagaacg cataagcaat tccatcatac
    41941 cggcgatcgt agggatcttg ctttgtccaa gcccttgaag tgtgtagcgt aaaatgaaca
    42001 ggactgctaa gatccagtaa agagacccat tgatattgaa gtaggtttgt gctaattcaa
    42061 atacacgtgt ttctgatggg ctaacaaaca attgaacaaa gaaatgaccg aagaaaatga
    42121 cgatagcacc tgctaagaga ctaaatccga cactcatcag taaagtttga cgtacccctt
    42181 gcaagattcg gccatattct ttcgcaccat agttttgtgc agtgaaagtt gccattgcaa
    42241 taccaaatga catcatcggc tgatttgcaa attggtcgat acgaccagca gcggcttgag
    42301 cagctacgac atctgtccct agactattta gtgctgcttg taacacgata gcaccaacag
    42361 cgatgatcga agattgaaac gccattggca aagcagcatt taggtgtaca gcaaactctt
    42421 ctttttcaaa tttgaaatct tttttgcgta actgtaacaa aggcattttt ttcttgatat
    42481 acactagaca cagtacgctg gaagaaactt gtgcgattac tgtagcaata gctgcacctt
    42541 ccacacccat gccaaaatag ataataaaga tcaaatcaag tacgacgttg atgatgaccg
    42601 caatgatcag aaagaatagt ggtgtgcggc tgtcaccaag tgcgcgaatg acattagaaa
    42661 gcaaattgaa actgactgat gcaaagatcc ctaataaaat aattgaaata aatgtttgtg
    42721 cttgatcaag tatttcagga ggagtttgca tcaattgaag catcggacga ataaacagga
    42781 gacttaggac agttaaaatc acagtgacga caagactaat gacaacacta gcagcaaaac
    42841 ttttcttcag accccgataa tcttttgcac cgtaacgttg tgcggtaata atggctaaac
    42901 cagctgttaa accttgggca aagccaatga tcaaaaatgt caggcttcca gttgcaccaa
    42961 ccgctgccag cgcattttta cctagcgtct gacccacgat gatcatatcg atcatattgt
    43021 agaactgctg aaaaacattt ccgatcagta aaggaacagt gaacatcaaa atcagtttag
    43081 cggggcttcc ttttgttaaa tcgcgcatct tttaaactcc ttatatcttt aaaatttagt
    43141 tagtagtata tagcgtttat cctgagaata ccaattagaa atcaatgata atttatgaaa
    43201 ctccataaaa agaagccaag aattgagtca aagaatcaac aacttggcct ggtctgtaaa
    43261 ataagggaca tccacgttta tctatcacct taatattgtc taatctcact tggtaaaagg
    43321 atcgtttctc tcgtaccgtc atcataggcg tatacttgag caggaaattg gttcgaatag
    43381 gcaaacggca aatcaatatc catttccaca ttgcttcctg cttgagaaaa atgcatcgtc
    43441 acttttccac gattttcgat caaatcaaag gttaatatat tttctaatgg aatgactccc
    43501 ttaagatcta ggtcaataat aaaccatata ctgtcaatca attcatctgg caaacttgat
    43561 acgacaccaa ctgaagcgta acggttgcgg ctgctatcaa aactttcaaa catctgttta
    43621 acctccttcg aatcaacgaa tgttttattt ttataattaa tcctaggata aactagaaat
    43681 acttacttca acgagggttc attctaataa agaatcagga aaaatgcaac aataattgaa
    43741 tacttttttt caaagtataa atttttataa aggtacgata aaagtatgcg aggaaaagct
    43801 tggtaaatta ggatttttcg tttgtaaagc catttacaaa agtggaagcc ccatatgaaa
    43861 ataaacgatt agaaataaaa aaggcgtgtt aaaagctgct gacccgccgc ttctaacacc
    43921 acctgattgt ttcagtatta ttcttctgtt gaaccgatca cttctggttc gccaccttca
    43981 cctgtgcttt cttcttcttc actttgagcg actacagcag cgatttgctc ttcactgtcg
    44041 gtcacgaatt tgtaatcgtc gttttttgga agatcggcta ctgtaataga atcacctaat
    44101 tccaagtttg tcacgtcaac ttcaattcgt tcaggcaatt tgtctggtgt agcagatacg
    44161 actactgtat acaagttttg agctaacact ccaccagatt tagcacccac tgattcgcca
    44221 acaagaacga cttctgtttc gacttctgtt tcttccgaca tgtttacaga tagaaattct
    44281 gcatgttcga aatgattggt aaaagtgttc gtttggatct tgtgaaccaa tgtattgact
    44341 ttttgtccat cgatgtccat cgtgatgact gtgttcgctc catgttcacg caacaatttg
    44401 cttagtgtca aaccatcgaa tgagataggg gtactttcta ctttataccc ataaacaaca
    44461 gctggaactt tcccttcgtg acgaagtttg tttcttaatg aacggggacg tacttctctt
    44521 ttacttactt ctaatgatac tgacataacc aaaattcctc cttaaaatgt gactgtctgc
    44581 tttggtaacg gacagatttt atttaagtga attctaaagg ctaatctcgt gcacatcatc
    44641 gaaggcaggg cgcttaaaaa agcgcaaaag gagagatgcg cgcatctccc cttagaaagt
    44701 caggattcaa cttttctcca ccaggtcatt acgctgtgta tgagaaatcc aattcacttt
    44761 actatttaac cgtaacgtga actgttaatt aagtcaagga ataactatga tgatgtattt
    44821 gcaagcaaga atattcaagg tataattaat tagtagtaat aagaaaggaa acagcatgcg
    44881 tttagataaa ttaatagaag aaaaattaga aacgacacgc aaggaaatga agcggctgtt
    44941 tgctttgaag caagtgatga tagatggcac agtcgaattt cgacaaaatc gaaatgtaga
    45001 tagtttactg catcaaatcg aagtagcagg tgaacactta gaaacaaatg agtcctatta
    45061 tcttctcaat aaacctgaaa aagctgttac agctgtatca gatccagaaa agacgacagt
    45121 aatcgatctg attgcaagtg ccgatcgttt ccaaccatta tatccagtgg gaagactaga
    45181 tagagataca acaggactat tgctgatcac ttcgaatgga caattgggat atgaaatgct
    45241 acttccagaa aaaaaggttt caaagactta tcaagtagtt gtgaacgaaa gggtgacacc
    45301 ggcagacgta acagcatttg aaaatggaat cgtattcgct gatgggtatc aatgtaagcc
    45361 ggctgattta aaaatactca aagcagacaa gcaccaaagt acggttttat tgacgatcca
    45421 agaaggaaaa ttccatcaag tcaaaaagat gttcttagcc caaggaaaga aagtgaccgc
    45481 attgaaacgg ctaagcatgg gaccattgga attagatgaa cagctaggag taggcgagta
    45541 tcgatcgttg acattagcag agatgaaaaa gttaagtatt tattttaaat aggaggtcaa
    45601 aaagatgaaa tataaaactt tattgtttga tgtagatgat acattgttag attttcaatt
    45661 aactgaagcc aatgctttaa gtgctttgtt tgcagaacaa ggaatcacat tgacaccaga
    45721 aatcgaaacc agctataagg ctttgaatca tcatttatgg caggagtttg aaaaaggcag
    45781 actatcacga gaagaaataa taggcagtcg ttttgggtta cttttccagc aatttgggaa
    45841 aacagtagat agtgatcaaa tggaaaaacg ctaccgccac tacttgaacc aaggtcatga
    45901 tcttgttcca ggaagtctag aaatcctgaa aaaggtccat ccgcatgctg atctttatat
    45961 tgtgacgaac ggtgtgtcgc acacgcaaca tcggcgatta acagatgcag gaatgcttga
    46021 ttacttcaag gatatctttg tctcagaagc tgtcggagcg caaaagccga tgaaagaatt
    46081 ttttgatcat gtcttttccc acattcctaa ttttgataaa aagcaaactg tgatcattgg
    46141 tgattctttg acttctgata tcaaaggagg aaatatggca gggatcgata cgatttggtt
    46201 caatagaaat aaattaccag aaatcgaaga aatccagcct acttatcgaa tcgattcatt
    46261 agaggaactt tattcattat tggaaattga aaaggattaa ttttcagaaa aatatagcat
    46321 tttcgtgttt tttcgctata atagattaga atgaaaaaac ggatacgaaa gaggttttag
    46381 tcaatgacaa aaagcaagcc aattatcatt ggtgtgacgg gtggatccgg aagcggaaag
    46441 acaagtgtca gccgtgcgat tttcaacaac ttcccggacc attccatcat gatgcttgaa
    46501 caagattctt attacaagga tcagagccat ttgagttttg aagaacgatt gaacacaaat
    46561 tacgatcacc catttgcctt tgataatgat ctgctgattc agcatgtagg cgacttactg
    46621 aactataaag ccattgaaaa acccgtgtat gactatgtag cgcatacaag aagtcaggca
    46681 acgatcattc aggaaccaaa agaagtgatc attctagaag gaatcctgat tttagaagac
    46741 gaacgtctgc gtgacttgat ggatatcaaa gtatacgtag atacagatga tgacattcgt
    46801 atcattcgtc gtatcaaacg ggatatggaa gaacggggac gcacattgga ctccgtgatc
    46861 gaacaatatt tgacagttgt taaaccgatg tatcatcaat ttatcgaacc aacgaagcgc
    46921 tatgcggata tcattgttcc agaaggcgga gaaaaccacg ttgctattga tttgattaca
    46981 acaaaagtag ctagtttctt aaaccataaa tagtgcgcag cgaaacagtt gaacggactg
    47041 cgaccgtttg aaaagcaagg attctgcttt ttgaacagtc accagccaac tgttttttta
    47101 tttataacaa gaggttgtga aaacagcatc ttgacctaag tattaaaaag aagaaacgga
    47161 aaatagctgt ttatatttta ccgttttttg agctaatacc gaaggtcagc tgattgagca
    47221 ccgtgaagta gaggttgtaa aaaagctgtc tttgcatcaa gcgataagag catccaaata
    47281 aaacagctcc tcacgttttt cgttgggttg ggcttattat cgtagatgca agcttttgaa
    47341 caccgtttaa cgagaggttg taacagaagt ggtcagatgc aataaataag aagaaactta
    47401 cgaaaattat ttctcgaatt tgtgtgagat ttcgacttat ttttttgaag aagctctttt
    47461 gtcgcacccc c
//
LOCUS       DACGLI010000018        47148 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.019, whole genome shotgun sequence.
ACCESSION   DACGLI010000018 DACGLI010000000
VERSION     DACGLI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.019"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            363..731
                     /locus_tag="IXT22_001077"
     CDS             363..731
                     /locus_tag="IXT22_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4862458.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            911..1852
                     /locus_tag="IXT22_001078"
     CDS             911..1852
                     /locus_tag="IXT22_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAQ4862459.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1921..2652
                     /locus_tag="IXT22_001079"
     CDS             1921..2652
                     /locus_tag="IXT22_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAQ4862460.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2796..4976
                     /locus_tag="IXT22_001080"
     CDS             2796..4976
                     /locus_tag="IXT22_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAQ4862461.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYFASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4996..5478
                     /locus_tag="IXT22_001081"
     CDS             4996..5478
                     /locus_tag="IXT22_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAQ4862462.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5494..6255
                     /locus_tag="IXT22_001082"
     CDS             5494..6255
                     /locus_tag="IXT22_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4862463.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6386..7720
                     /locus_tag="IXT22_001083"
     CDS             6386..7720
                     /locus_tag="IXT22_001083"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAQ4862464.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            8027..8512
                     /locus_tag="IXT22_001084"
     CDS             8027..8512
                     /locus_tag="IXT22_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAQ4862465.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8505..9188
                     /locus_tag="IXT22_001085"
     CDS             8505..9188
                     /locus_tag="IXT22_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAQ4862466.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9314..11959
                     /gene="polA"
                     /locus_tag="IXT22_001086"
     CDS             9314..11959
                     /gene="polA"
                     /locus_tag="IXT22_001086"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAQ4862467.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            12004..12840
                     /gene="mutM"
                     /locus_tag="IXT22_001087"
     CDS             12004..12840
                     /gene="mutM"
                     /locus_tag="IXT22_001087"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAQ4862468.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12804..13433
                     /locus_tag="IXT22_001088"
     CDS             12804..13433
                     /locus_tag="IXT22_001088"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAQ4862469.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13485..13817
                     /locus_tag="IXT22_001089"
     CDS             13485..13817
                     /locus_tag="IXT22_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4862470.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            14129..14620
                     /gene="nrdR"
                     /locus_tag="IXT22_001090"
     CDS             14129..14620
                     /gene="nrdR"
                     /locus_tag="IXT22_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAQ4862471.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14643..16016
                     /locus_tag="IXT22_001091"
     CDS             14643..16016
                     /locus_tag="IXT22_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAQ4862472.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            16016..16942
                     /gene="dnaI"
                     /locus_tag="IXT22_001092"
     CDS             16016..16942
                     /gene="dnaI"
                     /locus_tag="IXT22_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAQ4862473.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            17071..17511
                     /locus_tag="IXT22_001093"
     CDS             17071..17511
                     /locus_tag="IXT22_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAQ4862474.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17655..18356
                     /locus_tag="IXT22_001094"
     CDS             17655..18356
                     /locus_tag="IXT22_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAQ4862475.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            18353..19474
                     /locus_tag="IXT22_001095"
     CDS             18353..19474
                     /locus_tag="IXT22_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAQ4862476.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19489..20721
                     /gene="pepT"
                     /locus_tag="IXT22_001096"
     CDS             19489..20721
                     /gene="pepT"
                     /locus_tag="IXT22_001096"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAQ4862477.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20853..21761
                     /locus_tag="IXT22_001097"
     CDS             20853..21761
                     /locus_tag="IXT22_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAQ4862478.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21796..22068
                     /locus_tag="IXT22_001098"
     CDS             21796..22068
                     /locus_tag="IXT22_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAQ4862479.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            22079..23125
                     /locus_tag="IXT22_001099"
     CDS             22079..23125
                     /locus_tag="IXT22_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAQ4862480.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23376..25985
                     /gene="clpB"
                     /locus_tag="IXT22_001100"
     CDS             23376..25985
                     /gene="clpB"
                     /locus_tag="IXT22_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAQ4862481.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(26136..26807)
                     /locus_tag="IXT22_001101"
     CDS             complement(26136..26807)
                     /locus_tag="IXT22_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862482.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(26800..27294)
                     /locus_tag="IXT22_001102"
     CDS             complement(26800..27294)
                     /locus_tag="IXT22_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4862483.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(27314..28534)
                     /locus_tag="IXT22_001103"
     CDS             complement(27314..28534)
                     /locus_tag="IXT22_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862484.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28681..30516
                     /gene="lepA"
                     /locus_tag="IXT22_001104"
     CDS             28681..30516
                     /gene="lepA"
                     /locus_tag="IXT22_001104"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAQ4862485.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            30712..31623
                     /locus_tag="IXT22_001105"
     CDS             30712..31623
                     /locus_tag="IXT22_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862486.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            32619..32870
                     /locus_tag="IXT22_001106"
     CDS             32619..32870
                     /locus_tag="IXT22_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862487.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            32953..33225
                     /locus_tag="IXT22_001107"
     CDS             32953..33225
                     /locus_tag="IXT22_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862488.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            33315..33554
                     /locus_tag="IXT22_001108"
     CDS             33315..33554
                     /locus_tag="IXT22_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862489.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            33701..37984
                     /locus_tag="IXT22_001109"
     CDS             33701..37984
                     /locus_tag="IXT22_001109"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAQ4862490.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            38083..38448
                     /locus_tag="IXT22_001110"
     CDS             38083..38448
                     /locus_tag="IXT22_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862491.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            38450..38902
                     /locus_tag="IXT22_001111"
     CDS             38450..38902
                     /locus_tag="IXT22_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862492.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            39516..40826
                     /locus_tag="IXT22_001112"
     CDS             39516..40826
                     /locus_tag="IXT22_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAQ4862493.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            40849..41160
                     /locus_tag="IXT22_001113"
     CDS             40849..41160
                     /locus_tag="IXT22_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862494.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            41521..42777
                     /locus_tag="IXT22_001114"
     CDS             41521..42777
                     /locus_tag="IXT22_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4862495.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            42774..43319
                     /locus_tag="IXT22_001115"
     CDS             42774..43319
                     /locus_tag="IXT22_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862496.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            43320..43820
                     /locus_tag="IXT22_001116"
     CDS             43320..43820
                     /locus_tag="IXT22_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862497.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            43901..44457
                     /locus_tag="IXT22_001117"
                     /pseudo
     CDS             43901..44457
                     /locus_tag="IXT22_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            44477..44821
                     /locus_tag="IXT22_001118"
     CDS             44477..44821
                     /locus_tag="IXT22_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862498.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            44840..45751
                     /locus_tag="IXT22_001119"
     CDS             44840..45751
                     /locus_tag="IXT22_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4862499.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            45830..46822
                     /locus_tag="IXT22_001120"
     CDS             45830..46822
                     /locus_tag="IXT22_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4862500.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            46819..47037
                     /locus_tag="IXT22_001121"
     CDS             46819..47037
                     /locus_tag="IXT22_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862501.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
BASE COUNT        16089 a         7839 c        10117 g        13103 t
ORIGIN      
        1 agaaagaggt cgtgagcctg ccgtttcact ctgagtcaca aagagcaatt tcaaaaaata
       61 gcttctcatg tttgttgaat attgtgtctt gtgaccgagg agttgtcagg agaacaccgt
      121 ttaccagagg ttgtgacttg tttttagtca cgacctcttt ttttatttat tccatataaa
      181 tacacattat ttattccgaa aagtgaaagc gcaaataaca aaaacaacca acttatttat
      241 tattaaagaa aagcgtattt aagtaggacg attctgttga gagctttcgt agattttccc
      301 attttcctat ggtaaactga caaagttgag aatgttagaa cagatcgttt aggaggaaac
      361 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
      421 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      481 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      541 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      601 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      661 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      721 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      781 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      841 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      901 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      961 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
     1021 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
     1081 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
     1141 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
     1201 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
     1261 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
     1321 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1381 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1441 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1501 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1561 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1621 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1681 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1741 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1801 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1861 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1921 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1981 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     2041 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     2101 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     2161 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     2221 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     2281 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     2341 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2401 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2461 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2521 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2581 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2641 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2701 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2761 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2821 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2881 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2941 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     3001 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     3061 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     3121 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     3181 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     3241 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     3301 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3361 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3421 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3481 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3541 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3601 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3661 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3721 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3781 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3841 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3901 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3961 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     4021 attacgctat cgtcaacgaa gcaggcgctt ctgtttactt cgctagcgaa attgcacgaa
     4081 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     4141 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     4201 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     4261 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     4321 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4381 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4441 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4501 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4561 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4621 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4681 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4741 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4801 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4861 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4921 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4981 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     5041 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     5101 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     5161 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     5221 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     5281 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     5341 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5401 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5461 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5521 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5581 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5641 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5701 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5761 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc cgataaggct
     5821 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5881 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5941 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     6001 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     6061 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     6121 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     6181 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     6241 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     6301 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6361 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6421 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6481 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6541 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6601 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6661 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6721 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6781 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6841 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6901 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6961 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     7021 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     7081 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     7141 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     7201 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     7261 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     7321 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7381 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7441 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7501 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7561 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7621 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7681 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7741 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7801 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7861 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7921 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7981 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     8041 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     8101 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     8161 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     8221 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     8281 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     8341 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8401 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8461 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8521 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8581 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8641 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8701 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8761 cctactctct tttgaatggc ataacattag cggttactct tgcatactac gatattggaa
     8821 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8881 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8941 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     9001 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     9061 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     9121 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     9181 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     9241 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     9301 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9361 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9421 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9481 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9541 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9601 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9661 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9721 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9781 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9841 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9901 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9961 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
    10021 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
    10081 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
    10141 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
    10201 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
    10261 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
    10321 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10381 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10441 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10501 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10561 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10621 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10681 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10741 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10801 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10861 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10921 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10981 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    11041 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    11101 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    11161 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    11221 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    11281 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    11341 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11401 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11461 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11521 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11581 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11641 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11701 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11761 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11821 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11881 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11941 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    12001 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    12061 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    12121 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    12181 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    12241 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    12301 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12361 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12421 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12481 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12541 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12601 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12661 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12721 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12781 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12841 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12901 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12961 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    13021 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    13081 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    13141 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    13201 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    13261 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    13321 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13381 aaaaacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13441 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13501 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13561 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13621 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13681 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13741 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13801 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13861 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13921 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13981 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    14041 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    14101 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    14161 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    14221 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    14281 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    14341 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14401 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14461 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14521 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14581 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14641 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14701 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14761 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14821 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14881 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14941 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    15001 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    15061 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    15121 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    15181 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    15241 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    15301 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15361 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15421 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15481 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15541 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15601 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15661 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15721 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15781 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15841 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15901 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15961 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    16021 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    16081 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    16141 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    16201 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    16261 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    16321 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16381 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16441 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16501 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16561 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16621 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16681 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16741 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16801 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16861 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16921 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16981 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    17041 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    17101 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    17161 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    17221 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    17281 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    17341 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17401 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17461 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17521 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17581 tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta taattatcta
    17641 gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca gtgggtgact
    17701 ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac ttacccgttg
    17761 cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt caaggtcctt
    17821 atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc accgtacgcc
    17881 ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc acgattgcgg
    17941 gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat caacgcttaa
    18001 gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta cgatcttggc
    18061 tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat aaaaaaatat
    18121 atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa atggagctga
    18181 tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa tggacaagag
    18241 agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat caagaggcac
    18301 gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag ccatgacaat
    18361 cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc tagctgaaga
    18421 aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac gagtaatgat
    18481 gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa tcgatttgct
    18541 gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg atcagccaca
    18601 agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag cacacacgaa
    18661 catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg gtattgaagt
    18721 ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg tttatgtacc
    18781 tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg gtacacaagg
    18841 tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc cggaagctgg
    18901 tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg caaaagttga
    18961 ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt cagctcatcc
    19021 ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa tgtttgggtt
    19081 aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag aacaagtaaa
    19141 agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa aatcctctgt
    19201 gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag caatcgccca
    19261 aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg atatgcaaag
    19321 cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca agcaacgatt
    19381 tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact ttttcgtttc
    19441 tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat gtacgaaaat
    19501 cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc aacaagcaaa
    19561 acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa agaattagaa
    19621 gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat gggaacatta
    19681 ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat ggatacagca
    19741 gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg cgagtctacg
    19801 atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc aaatttgaaa
    19861 aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg agcagatgac
    19921 aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa tccttctatc
    19981 cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt cggagcggat
    20041 aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg tggtccttta
    20101 ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat ccaagggaaa
    20161 aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt agcaatcgat
    20221 tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata cgaaggtttc
    20281 ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta tatcattcgc
    20341 gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat ccaagaagag
    20401 ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca atattacaac
    20461 atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca agcaatgatc
    20521 gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg ttcaaaaatc
    20581 tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat gcacggacga
    20641 ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt aaaaattgca
    20701 gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc gttcgtccca
    20761 atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg ttgtcccgcc
    20821 ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt ttttataaca
    20881 aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat tatgtaaaag
    20941 aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt gatgatgcgg
    21001 aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata ggtggagacg
    21061 gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac catgtcggat
    21121 tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc ctcaaaaaag
    21181 aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat ggtcaagtca
    21241 atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca gcagtttgga
    21301 tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag ttttttaagt
    21361 tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag cattggaaag
    21421 gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt acaaattttg
    21481 acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct tccttagata
    21541 ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat acgatccccg
    21601 gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa tctgtgggca
    21661 ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt gtatcaaaag
    21721 gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag ttaacagaaa
    21781 gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta ccttttcatt
    21841 gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag aactagcggc
    21901 tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg tttgggagga
    21961 ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac tataggattc
    22021 gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg agcaggagat
    22081 gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga ttgtgatttt
    22141 tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg aattgctgtc
    22201 taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc aaatcgctga
    22261 agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa cgaaagatgg
    22321 gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta caggaacgct
    22381 gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg gagcaggggt
    22441 gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat tagctggctt
    22501 ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt ttatcatcgc
    22561 tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg tcagcttgaa
    22621 tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc gtttgcggaa
    22681 atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc aaaccattat
    22741 ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac ttgtattttg
    22801 gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt ttctactgac
    22861 catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc ctgctggtat
    22921 tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa cagttgacgc
    22981 agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc tctatggatt
    23041 tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag aagtaaaaaa
    23101 agagaataaa gaaaatcaag ggtaggtctt ttataagatc tacccttttt atcaaatcaa
    23161 agaaaaacgt tatggataag ataattttac gtttgtttgg ctcttttttt atatacatac
    23221 aatcaatttt gtttttttaa gatttatata agtcgagaaa aaaagtcaaa aaactatgtg
    23281 tatattttga ccaaaattga ccaaagcgat ataatagttt ttgtaaagat caaagaaata
    23341 agtgatctta cctttaatta ggagggtata cctgtatgaa tattgagaaa atgactacga
    23401 cgcttcaaga agcgattgct gaagctcaac agattgcggt cactcgaaaa catcaagata
    23461 tcgacattgc ccatgtatgg aaaatctttt tacaatctaa tcattttggt cgaaatttct
    23521 atacggatgc cggattggat gtcgaatctt ttgaacatga aattgatcgt ctactggatg
    23581 agtatccagt tgtttctggt ggaaacgtcc aatatggaca aaacctcagc cagaatttct
    23641 ttcgattatt gaatgaagca gaccaaatac gtgaaagctt cggcgacgag tttctttcaa
    23701 cggaagtcgt tattttagcg ttgatgaaat taaaaaatta tccgttaact gtttatttga
    23761 ataaaaacgg attatctgaa aaagaattgc gtaaaaacat cgaagagatg agaggaggag
    23821 aaagagtgac ctcacaaaac caagaagaac aatacaaagc attagaaaaa tacggcgttg
    23881 atttagtaca gcaagtcaaa agcggaaaaa tggatccaat catcggtcgt gatgaagaaa
    23941 tccgtgatgt catccgtatt ctttcacgaa aaacaaaaaa taatcctgtt ctgataggag
    24001 aacccggtgt agggaaaacg gcaatcgttg aagggcttgc tcaacgtatc gtacgcaaag
    24061 atgtgcctga aaatttaaaa gataaaacga ttttttcatt agatatgggt gcattgatcg
    24121 ctggagcaaa attccgtggt gaatttgaag aaagactaaa agcagtcttg aaagaagtca
    24181 aaaaaagtga tggacgtatc ctcttgttca tcgatgaaat ccacaatatc gtaggggcag
    24241 gaaaaacaga aggaagtatg gatgccggaa atctgttgaa accaatgctt gctcgcggtg
    24301 aattacattt gatcggtgcc acaactttag atgagtaccg tcaatatatg gaaaaagaca
    24361 aagcgttgga acgtcgcttt caaaaggtat tagtcaaaga accaacagtg gaagatacga
    24421 tcagtattct gcgtggatta aaagaacgtt ttgagatcca ccatggtgtt aacatccatg
    24481 acaacgcatt agtagcagca gctactttat ctgaccgtta tattactgat cggttcttac
    24541 cggacaaagc aatcgatttg atcgatgaag ccagtgcaac gattcgggta gaaatgaact
    24601 ctatgccaac ggaattagat caagttacta gacgtttgat gcagttggaa atcgaagaag
    24661 ctgcactgaa aaaagaatca gatgatgcaa gtaaaaaacg cttgaaaaat ttgcaagaag
    24721 aattagctga acttcgtgaa gaagcaaatg cgatgaagat gcagtgggaa acagaaaaag
    24781 aagaagtcaa ttctgtttca gcaaaacgtg ctgaaatcga taaagcaaaa cacgaattag
    24841 aagatgcaga aaataactat gatttagaac gcgctgctgt attgcgtcat ggtacgatac
    24901 ctcaattaga aaaagaattg aaggaattag aagctaaagc aaaagacagc gagattaaga
    24961 tggttcaaga gtccgttacc gaaaatgaga ttgctcaagt cgttggcaga ttaacgggta
    25021 tccccgtaac gaaacttgta gaaggtgaac gagaaaaact aattaaattg aatgaaacac
    25081 ttcataaacg agtgattggt caagatgaag cagttgatgc ggtcagtgac gcggtaattc
    25141 gttcacgggc tggattgcaa gacccaaatc gtcctctagg ttctttcctt ttcctaggac
    25201 caactggtgt cggaaaaacc gaattagcga aagcgttagc tgagaacttg tttgactcag
    25261 aagatcatat ggtacggatc gatatgagtg aatatatgga aaaacatgct gtgtctcgtc
    25321 tagtcggagc tcctccaggc tatgtaggtt acgaagaagg tggtcaatta acggaagctg
    25381 tcagacgaaa tccttataca atcgtcttgt tggatgaaat cgaaaaagcg catcccgatg
    25441 tcttcaatat cttgttacaa gtcctagatg acggacgctt gactgattca aaagggcgag
    25501 tagtagattt caaaaatacg gttctgatca tgaccagcaa tatcggttca cagttactgc
    25561 tggaaggcgt gactgctgat ggaacgattc cagaagcagt ggctgaacaa gtcaacacgc
    25621 tattacgtgg aaacttcaaa ccagaattct tgaaccgaat cgacgacacg attttattta
    25681 caccattgag cctagacaac gtgaaaggaa tcgttgacaa aatggtggcg caattggcac
    25741 aacgtctgga acatcaagaa atcctgctga caatcagtga tgaagccaaa acgtggattg
    25801 ctgaaaatgc ttatgaacca gcatatggtg caagaccatt gaaacgattt atcactaagg
    25861 aagtagaaac accactagct aaagaaatcg ttgcaggaca tgttatgcct aaatcaaaag
    25921 taacgattac tttacttgat ggacaacttc atttcaaaac agaagagcta gaagaaatcg
    25981 tctaatcttc cattgagact ataaaagaaa aaaggggtct gacacaacta gtgtcagacc
    26041 tccttttttc aaataaacag tgttccagaa gtagtttctt cgaaaaataa gccgaaattt
    26101 cttgaagctg cccgcttctg tcacaacctc ttttattagg tatttttcac tttttctaat
    26161 ttataacttt caaagtaacg ctcatctttt ttactttgag accatgcaaa caatcccatt
    26221 aaggcagcac ctatcgtatt tgtcagcaag tcgcccatcg tatccatcaa tgctgctcgt
    26281 ccgacaaaca gtgtgccatc agaagcagca aaacgttgaa gattcatgcc taagaactgg
    26341 tcgcataaga attcccagaa ctcccaaaac acgccgcaaa gtccagcaaa cgcaaagccg
    26401 aataagagga acaaccaagg actggttttt gatatctcag catctttcat caagtaacca
    26461 atcaatccat agccaagagc tgtcaggacc attggactca ccgcatgtaa gattttgtcc
    26521 caaaaagaga tgatactgat caaatgcatc cctgtgccta aaaagacaga gatgaacaag
    26581 aaaaaccagt aaaacaaaac gattgctgct ggtattttaa gtttgaaaac tttcaaaatg
    26641 acttgtggca tgaaaatcaa tgcaatccct aataaagatt ccacgataaa tgtgattcct
    26701 tgagaagtcg aatatttttg tgtgataaat tcataaaaat tatagcagac aacgaataca
    26761 ccaaaagcaa gtaaagctat ttgcaccttt ttgatttctt taatcactga aagtccctcc
    26821 atctaaaaat ctttttactt ctgaaagcaa ctcaatttct gaagaaacca cttttccgtt
    26881 caatttgatc aaacctattg tatataagtt caggtagtga aattgatttt cagctgtttc
    26941 ttgtagtgca gcgatttttt tcgggtgggt tccgccttgc tgtcgagtat cagtatataa
    27001 gccgatcact gggatgcctt tcgcataagc cacaccgatt tccgatgcta ccccggcatc
    27061 gatcgtcagc ccatctagta aagcaatcat taaatcacta gccaacactt tttctgtgtc
    27121 agcaagagca atcattcgac tgtctgcata agcagttttg tcattgattg cttcattttc
    27181 ttgaggaaga tagatcgaaa gctcagaaga gagctctctg atttctttaa ctaactgttg
    27241 gttatataac aaatcacttt tagcaaacat tggtgcggca aaataaattt tcatctaaac
    27301 atcatccttt ttatcaaaaa taatcgctaa agtaagcttc catgtttgga atgatacgct
    27361 ctagtgactt cagtgtttct tcatctgttt ctaaccgttc gattcttgcc aaataagaag
    27421 cacggcgata attcatcatc aagcaagtca atgtttggat atccagtcga acggattttc
    27481 ctataggttc atttaagaca cggacttgtc cctgttcatc ccatgttaaa gcgaagacac
    27541 cattattcca aggagcgaca ggatcttcaa tgatgaaatg aaaagcatca gctgttccaa
    27601 caaacggaaa ccgttgaagg aattctttta catcaacgat ccgagccata aaatatggtt
    27661 cgatctgctc tttgatctga ctatcttcaa tcaaaaatgc taaaggctca tttttataaa
    27721 tatctccatg tacccagtag atcatggaaa aatgtgcgga aataaagttc cataagccat
    27781 ttcgagcttc ttgatcaaga tagaacattt cttttacgtg aaatatttct tcagctaccc
    27841 agtagaacag aacacctctt ggttcatggt tgctatcgta gtagacagcg gctgtgcgct
    27901 catcttcatt ttcgaaacgc caatactctt cccaatgaaa atcactgcgg aataaagcac
    27961 catggttttg ttgggcaaat ttgtcataaa cggaaaatac gtctggatga tcaactggta
    28021 atcgctcaac cataccactt actgggattt gtttaggtag ctgtgtatct ctgattttaa
    28081 aggaaagttt atcagacatg atttcccatc ctttacgccg atagtagggg atactgtaag
    28141 gatacaaata agagatccat tgcttattct tgcgcatatt atccaatgca acgataatta
    28201 gatcttgcat caatccatgg ttagcatatt ctggataagt tccaactcca gtcacaccac
    28261 ccattttata acgtgcaccg tgaatattga cttcacaagg atagatagcg atttgagaga
    28321 tcagtttatt ttcgtggaac catccgaaca ctttcgatac ttccaaaatc ggttttttgg
    28381 aacggataaa agctcgttta ttctcaaacc cgctttcctc gatgtctgct tcagtcactt
    28441 ggaacacata ggaaagcaat tcattgaatt gatcgatatg ttcttgagtg accggtttta
    28501 attcaagatt ttctctaaaa tctttttgat ccattttttc atctccattt attagcttga
    28561 taacagtata gcaaaattct acaaaaaaaa cttctatagc tgactaatta aaaactcttt
    28621 aaattactgc ttttcgttgg tataatggaa agtgctgatt atatgaaaag aggagacgct
    28681 atggatataa agaaaatgaa agaacgccaa gagcagattc gtaatttttc gatcatcgct
    28741 catatcgacc atgggaaatc tacattggcc gatcgtattt tagaaatgac gcacactgtg
    28801 acgtctcgcg aaatgcaaga tcagctgtta gactcgatgg atttggaacg tgaacgtgga
    28861 atcacgatta aattaaatgc tgtagaactc aattacacag cgaaaaatgg agaaacatat
    28921 atctttcact tgattgacac cccagggcac gtcgacttca cctatgaagt ctctcgaagc
    28981 cttgctgcct gtgagggtgc cgttttagtg gtcgatgcag cacaaggaat cgaagcacaa
    29041 acattggcca atgtttattt agcgttagac aatgatttgg agatcctgcc agtcatcaat
    29101 aaaatcgacc tacccgcagc agatcccgaa cgtgtccgtc aagaaatcga agacgtaatc
    29161 ggaatcgatg ctagtgaagc tgtattagcc agtgccaaat cagggattgg gattgaagat
    29221 attctcgagc agatcgtgga atatgttcct gcaccaagtg gagacttaga tgcaccgcta
    29281 aaagctttga tctttgactc tatttatgat agttaccgcg gtgttgttct aaatgtccgg
    29341 atcacggacg gtatggtcaa acccggagac aaaatcaaac tgatgagtaa tggcaaaaca
    29401 tttgatgtta cagaggtcgg ggtcttctcg ccaaaagcag ttgctagaga ctttttgatg
    29461 gtcggtgatg tcggttatat cacagcaagt atcaaaactg tccaagatac acgagtaggg
    29521 gatacagtaa cgttagcaga caatcctgcc gctgaagctt taccaggtta ccgaaaaatg
    29581 aatccgatgg tttattgtgg tctttatcca attgatactt ctcgttacaa cgatttgcgg
    29641 gaagctttag aaaaactgca attgaatgat gctgctttac aattcgaacc agaaacctct
    29701 caagcattag gttttgggtt ccgctgtgga ttcctcggac ttcttcatat ggatgtcgtc
    29761 caagaacgct tggaacggga attcaatcta gaattgatca cgactgcacc atccgttatt
    29821 taccatgtta ataaaacgga tggtacgact gctacagtag ataacccggc agattttcct
    29881 gaacctgtaa cgattcagga tgtagaagaa ccattcgtca aagcacagat catggtccca
    29941 aatgattttg tcggtgcagt aatggaactt tctcaacgaa aacggggaga attcattacg
    30001 atggattatt tagatgatta ccgagtaaat gtcgtctata atattccgct ttctgaaatt
    30061 gtctttgact ttttcgacaa attgaaatca agcacgaaag gctatgcctc attggattat
    30121 gaaatgtctg gttatcaaaa aagcaagtta gtgaagatgg acatcttgct gaatggagaa
    30181 aaagtcgatg cattaagctt tatcgttcac cgagactttg cctatgaacg tggaaaagca
    30241 atcgttgaaa aactgaaaaa actaatccca cgccaacaat ttgaggtgcc aatccaagca
    30301 gctattggac aaaaaatcgt tgcccgttca gacatcaaag ccttgcgtaa aaacgtcttg
    30361 gctaaatgtt atggtggaga tgtttctcgt aaacgtaaac tcttagagaa acaaaaagaa
    30421 gggaagaagc ggatgaaaca aatcggctcc gtcgaagttc cgcaagaagc cttcatggcc
    30481 gttctgaaaa tggatgagca agatagtgtg aaataactta taatcaatcg aaaaacctat
    30541 taaataaacc tttttgagta gatgcaacac tgaggattat ctgtataaaa gattttaaac
    30601 tgtcatttgg ttatcacggc gatactaaaa ttaacaaaat tggaatattt ttcttgaaga
    30661 tttttagctg tcagtatatg atgaaagcat ctcataggag gtgctttttt catggttgat
    30721 aattcaagtg gaagggttct taaatctcta agaaaagaga aaaaactatc tcaaaaaaag
    30781 ttagctgatt tagcaggtat ttcacaaagt actttagtta aatatgaaaa agggtcaaga
    30841 aaaatcccta aagacgtaga taatactcta agcaagattc tgaatataga aactctaata
    30901 aaagatgagg aagataagat tgagattctc atcggtaaac taattgcata cagagatatg
    30961 aataagttac ttaacaaaga gttagctgat aatataggaa ttagtgaagt attactcagt
    31021 tatgtgttaa atagaaagag aaatccgtca aaagaaatgc aaaaaaaaat cgatattttt
    31081 ctattaagta atgaaaaaga aattttgaag gagattaatc gtgatagtga gatatttagt
    31141 ttatcaaaag acgataaaat tgttatggga aaaagaatac gagaagtccg aaagaaccgg
    31201 gaagagacgc ttgaaaaatt tggtaaaaac tttaccatct atacaggcaa aaatgttata
    31261 agtagatggg aaaaaggtat taatattcca gatattgaaa aactaatgaa tattgcctat
    31321 cttggtaagg tcactgttcc ttaccttatg tacggagaag attataagaa tatacttcca
    31381 aaagatgaaa gagttagcga ttttaaaaag ataaattctt ttagtatggg attaaggatg
    31441 aggaaaatta ggaaagatta ttatctagaa agggaggagt ttggaaagct tttttctcct
    31501 tcaatttcaa aatggtccat agataggtat gagaatggta gagatatacc caatactaat
    31561 cgaattatcc aatatgctta tataggaaat ctttctttag aatttttgat ttacgggata
    31621 taaaaatagt ttacgtcgat acttattaag ttatcgacgt tttttattat agaaaaaatt
    31681 tataaaagga ggtttcttga tatgataaga aacaaaaagg gtttgttgaa agttgcttta
    31741 ctggcagctt ttttctaagt aactttttga caagctcaat ggcaacacaa gcggaagaag
    31801 taatacaaga actaactgtt atgaataaca gctagataaa atgggctatg tatgttatcc
    31861 aacaatttag taatcactag aagcctagcg aaagttcgct tgataagtta tagatgagta
    31921 ttgatttgta gtgtttccaa atcaaaaggg tacagagcca catgaaatat gttgtcctct
    31981 gcagcgtcag gatgggaatc cataccatgg agattcggag atctgtgagg gaatacttac
    32041 gtggttaata tgtcagttgt gttggacgta gtaatggtca tagtgggtag attgactgaa
    32101 ttcttatatg agaaaatgaa accaacaaga agatagggtt atttatacag aattggggat
    32161 cttttctgga aaagtaatcg gataatgcga gattcgtacg gtctttttta aatttctcta
    32221 aaaaaaacgg catcgaatgg gttgggtgat tgataagcaa tgaatcatag actgatatag
    32281 aataaaaaat gattctattt atctttttac atctatcgtt ttttcaagta gccgcaaatt
    32341 atatcagcat tcaacaattt ttgtatacaa gttctagtaa aaggatctga agaaaaagtt
    32401 ggttgttgtg aagataaaaa aagaatcagg ttttactgag tttttcttca aaatttgtgt
    32461 tattaggtta ggacaaagat aagaagaagt atgaagattt aaaaaaggaa tgaggaaaag
    32521 atagtaattt ccgattattg gagttttttt atttataaag aagaagcgaa taagttgtga
    32581 ttcctagatt tcgcgcgtga ttaattaatg agcaaaaaat gcggaaagtt ttagtgttta
    32641 atacacgagg acaaagtttc ttaggtattg aaggcacacg tgtaacggtt gatgggtggt
    32701 gtgattgttt cgaggttgga aaacatgttg aacttatggc atttactgag ctaaaagata
    32761 agaacaacgt ggaatttttc gagagtgata ttggttggga cgatcatgaa gaagtttatg
    32821 gaaaatttat tttgcggaag ggaaattctt atacgaatgg ggaagcataa gtagcgattt
    32881 gttagagatc attgatagga ttgaaattgt cgggaatatt tatgagaatc tagagttatt
    32941 tgaggtgata gaatgagtga tggttttgaa caagtatcaa taattaaaaa tcaagttcgg
    33001 gagattctta gaaaaaaagg ctatttggta gatagttatt ttgaaggaga ttacgaaaca
    33061 tgggtaggtg tctatgctcg tccagagaat aaacctacct atttagatcc tacgacgtca
    33121 gaagatgcct atttacaaaa taggtatcga gtagatggtt ttaagcaaga ctttgcggag
    33181 tggtttgaat gggaaattga aaacggagaa gtaaaagaag aataagagta cttgttgtat
    33241 caaaataagc cagtagaaca accaaaccag tagctagtaa tgacaataat actgaggaat
    33301 cggatcatta tggtatgatt gatatttctc ttccagaaga tcttaagcca gatcctgtaa
    33361 caattggcaa tagtgtcatg atttttgatt cattagatga agctatgtca tatggttgga
    33421 aagaaattaa ggatgaaggt agtaattggt atggcatgag atttggtgat ggtgaagttg
    33481 ccaaaaaagc tggtattcca attgggaaat ggacagttga tttccacgaa gcaggttctt
    33541 tttttgttct gtaattatag tgggagggta aaatcattga tgaaatgtgt tcagataaga
    33601 gcgccagata aaaatagaag agacagttca cgtcgttatc acttttggta acggcgtttt
    33661 gttttattat ataaaattct caggaaaagg aggaattctt gtgtatgcaa aaacgaaaat
    33721 gaattggttg aaagcactcg cattggtggc tttttctcaa ttctgtttct tggtgggaac
    33781 tgctcaagca catgcagaag aaacgacggc tatacaacct acgatggaag ccattgccca
    33841 agtcgcttct gaagtgacag aagtccaacc agcagaagcc ggggtcccag ctggtgaagc
    33901 cactgttgaa caggcccctg tgacagaagc gccaacggtc aattccaaaa cgactctcga
    33961 tcagacgatt ggggaaacac aacacccagg gaatagtcct ggtacttcac aaccagttga
    34021 agaaactgcc tcaattacaa cccctgcttc agaaacgtcc actctagaag gagaaaaagc
    34081 tgccgaagca acgccttctg tgcagccaga gtcttctgag aaacaagcgg aagaaaagaa
    34141 acgaatagaa gaaacagtgg aacaaccagc ggctactgct gacaaagaag gaaaaaatga
    34201 ggaaaacgtt gaaaaaacaa tctcttcaac cgcagctagt caaaatcaac caacgaaacc
    34261 aaacaaagaa tctacggcta gtattgaaaa tcaaaagaaa aaagagcaga acattccaaa
    34321 aacaggtaca cctacactgt tagtaacagt accaaccaat cgttcggttc gtgttcgccg
    34381 tgcaaccaat gcagctgttt taggtggtcg gaaaattgat tggggcgaaa atattggtgt
    34441 tacttctagt ccgaacaatc taaacttcac tttaaattat atggttcgtt ttgagattaa
    34501 tggacaagtg gcgttttgta ttgagcctgg tgtctcagcc gcagaaggtc aagtttatac
    34561 agctactgct ttgaaaaact atttgaaaaa ttcaaatgta cggaaaaaaa caagcttgat
    34621 ctcttattta ggatatgtca caaataaaga caaatccgat gaacaataca ttgcggcaca
    34681 atttatgatt tgggaagctt tgggcacaaa aatcccaatc aaaaatatcc gtgttgatta
    34741 tgatcgtcga aaagcagaaa ttcaacgttt gattaataac tttggtgaaa aagcaacttt
    34801 taataatcaa acacatacgg taaaaattgg cgaaacgttg aaagtaaaga ataaaaatga
    34861 ttttttgaaa tatgtgaaag acattcaaaa accaaaaggt gtcaatgtat ctattcacgg
    34921 caatgaagta tggattacag tcacaaaaga ggcaccggat aaagcaaaaa ttcaattgaa
    34981 taaaattaaa gttcaaggtg cgccattagc ctatcgtcgt ccaggagctc aaacaattgg
    35041 tgtgttacat ccaacagaac ctaatgcgtc tgttattaat ttacaaattc taaaacaagg
    35101 aaacattcgt gtgtttaaag aagatgcgga aactggtgtg aaagcacaag gtgcagcttc
    35161 tttagaaaat gcggtctatg gtttgtatca agcagatggg aaaaagatta aagaaattac
    35221 cttgaaaaaa attaacggca aagtacaggc agaaattaaa gatcttgatc ctggcaaata
    35281 tgttttaaaa gaaatcaaag cgccaaaagg ttatgtgctt tctgatgaag caattgaaat
    35341 tgttgttgaa cctggaaaaa ctgtcaatgc gaccgcaaaa gatcaagtga tcaaaggaac
    35401 cattgattta gtgaaagttg ctaataaaga tttagtcgat tcaacgaatc cagataacaa
    35461 accaaaatta gctggcattg aaatcacttt gacgtcaaaa acaactggca aagtggtgaa
    35521 aaccgttgtg acagacaatg atggttatgc tacttttggt aaaaataccg ttgtctttga
    35581 tacgtacatt ctttctgaaa ccaaaggaaa agaagggtat aaactatttg aaccacttga
    35641 agtcacaatt tctgaaaatg ggcaaacttt ccattatgtt ttagaagata aagtaattga
    35701 acaacgtctt aaagtggtga aagtggatca agaaacagga aaagtgattc cacttgctaa
    35761 tacagaattc aagatttttg atactttagc caatcgttat gtcacaatgg agattccaaa
    35821 tgatacagaa acaacggata tctttaaaac caatgaaaaa ggctttttcc taactaacgg
    35881 tacacttact tatggaaaag atcgctatcg tttggaagaa atcaaagccc ccgtaaatta
    35941 cgttttgaat caaaacccat tagtgttctc gattaccaat gatacagaac cgatcaaagt
    36001 gatccatttt gcgaaccgtc aagcacggaa aagtgtaaaa ttattcaagt atgaagaatg
    36061 gaacaagaag aaaacgccgc tcgcaggtgt gaactttacc ttgtataacg gtaaaaatca
    36121 agcaattggt gaatatacca ctgatcaaaa cggggaaatt ttagtgaaag gtctagttgc
    36181 cgatgactat tacttcttgg aaaatgcccc attagaaagt ttccaaccaa atacagataa
    36241 acaagcattc acggttgcat tcaaacaaaa tgcgccagat gatggggaaa cgttagtggt
    36301 ttctgtacgt aattacttga ttccaccaaa actagaaaca caagcgtcaa ataaagccga
    36361 tggtgaaaaa gtggttgatc cattagaaac gatcgtcatt aaagacagtg tttcttatac
    36421 caacttgttt gtcggaaaag aatacaccat ttcaggagta ttgatgaaca aggcaacgaa
    36481 tgcgccaatt ttacaagatg gcaaagaaat cacaagtacc ttggccttta ttgcagacaa
    36541 agtcaatggc acaaaagacc ttgaatttgt ggttaatgct agtgttctga aaggtcaaac
    36601 gatcgttgtt tttgaaaaac ttttccgtga tggcattgaa gttgcagcac atgcggatat
    36661 caacgatgaa gcccaaagtg tgaaagtgaa taatccaacc gttcatacca cggctgtctt
    36721 tgaagacgga ttgacagtcg cagacccaac aggattgttt accttaaacg ataccgttga
    36781 aattaccgag attcttccag gaaaagcata cttggtcaaa gggatcttaa tggataaagc
    36841 aaccggtgaa cccttgcttg tgcatggaaa tacggtagaa acgagtgttg gctttattgc
    36901 caaagcagaa aatgaaacgg tgatcgtacc atttaccttt gatttgacag gtataaatgg
    36961 tcgtgaaatc gtcgtgtttg aaagtctttt tagaaatgat gaagaactag caaaccataa
    37021 agacatcaac gacaaagggc aaacggtacg agtaactaac ccaagtgtac gtacaacggc
    37081 tacacataaa cccactggct tgaaagaggt taatccatta acgaaagtca ccattacaga
    37141 cgctgtgaaa taccacgatt tggtcgttgg aaaaacatac acagtcaacg gtgttctaat
    37201 ggacaaagta acggaaaaac cagtgctagt agatggaaaa gaagtcacaa gtaccttaac
    37261 gtttgtggca gaaacaacgg atggtacagt caatctagac tttattctag acgcacgtgc
    37321 gttgcgaggc aaagaagtcg tggtctttga agatctgttt agagaaggcg tattattggc
    37381 ttctcacgca gatattaccg acaatgacca aaccatcaaa atcagtaatc caaccattac
    37441 gacgaaagcg acgaataaaa atggcggaaa agagatcttg gccttgccaa atcaaactgt
    37501 gcttgaatgg gtcaaagtag acggtcttgc gattggtcaa atctatcgct taattgttca
    37561 aggctactta acaccagacg gcacaccatt tgaaggcact catgcggaaa aagtctttgc
    37621 ggccgataaa gaaatgatgg aattcttatt tgaattctta gtggacggtc gcaatcttgc
    37681 aggaaaaggc ttgagttttg cggaatggct ccaagcgaaa acggaagatg agaaagaaac
    37741 gtttgaagaa gtggcgaaac acaatgtaga tctaacaaac aaagatcaaa cggttcaaat
    37801 tgtggaagcg ccaaaaccac cgcaaccagt gaaaccagaa caacgggtta aaccagctac
    37861 tgttgtacca atgttgccaa aaacaggtga acaaacaagt agtatactta tggttcttgg
    37921 attagtagta ttagtcattg ctttaggtat aacactttat aaagtacgta aagccaaaga
    37981 ttagtcatga ggaacaagcg gttaggattt ttaaccgctt gtttgattgt aatgtagaaa
    38041 tatttagaat ttattttggt ttttaagagg aggaaaaact ttatggcaga aaaagcattg
    38101 cgtatgaaga aagagttttt aggtcaagta tttttattgg gttcacggga acctaatcca
    38161 ccaaaggaaa ttaatggtgt gtctgggcga tatgttcaat tacaagcaga gtgttcgcga
    38221 gaagaacagc ctgctttttt tgtttatctc acagctgaag aggataaaag attacgatta
    38281 ccagaaaaag aggtgcgtat ttcatttgaa gaagcttatt ttgtttttcg taaagaacga
    38341 gtgaatagtc gtgaaacaaa tgatatggga caaacagagc gtcgaacaac tggctatcaa
    38401 gatgttggtg tctttttaac tggtgtaaaa attggggagg ttttgtaaga tgggattaaa
    38461 atttccaaat aattatgaca ttacagaagc attagatgaa acttgtttag gagccgtacg
    38521 ctttggcgca ttagaagagt ctgatcgtgt atttgataat gaaacaggcg attatacggg
    38581 agaaattcga tcacagcgag cacaattagt ttttggaaat ccagatgaac caaagattgc
    38641 acgacgagtt aaatttccag cagatgtaga tttgactggt tttaaacgac gtgatcctgt
    38701 gaaattaatt gatccagaat atcatgtggt atatattcca gcacaagatg gcaatcgtga
    38761 atattcagat ttagtgattt atgcgaaagg attagagaaa gtagaagctc caacaaataa
    38821 tcctaatatg aaacaatcac aagaaaaagg tttagatcaa aaacaaccaa gtgttgattc
    38881 taaggaaaaa gagaaaaaat aaggtttttt tgaaagaata ggaaggagtc ttcctattct
    38941 ttttatctaa gatagaagga aggggagatt ttgaattcag ataaaaccaa tcaaatactt
    39001 tgagagattg tgcttgttat caaaatatcc aacaattgat tgagtatttt ggagacaatc
    39061 caacgatttt tgtacaaaca aatgcatata tttgtgcggt tattgggcag tgtatgtttt
    39121 tacgtgatct tgttcgtttt tcattaccgt accagtggaa acaagatcat caggaagtga
    39181 tttggattcg tatagtacga atatgtaata tgtgtgcaca cccttataaa aatcgattaa
    39241 atctttttcg attatgtttt tttactaaat gtgatattcc tgtattagtt gctttttgtc
    39301 aaaagttttt agcacaggaa aagtaaaaac agaaaggagg aatgtgacaa ttgaaagctc
    39361 attttttcaa gtatcgtggt cggcgaattc gctatttcaa tcgttattta tggttttgct
    39421 attatggttt ctttttgttt ccatttttga ttctgttagg ttggtttagt tggaaagtat
    39481 tttatccacg tttaagtacg ttttcgaatt ggcaaatgta tcttattcct ggaataagta
    39541 ttgtgttgta tttgttgctg gttagtgggt taattttagg gttgatgcat tggtcgcgac
    39601 taaaagaagg atattttgcc tctgtttatt ggcgtcagtt acttgttcga atgttaattg
    39661 acaatcggtt tgtttataca aagaaacaag ttagtgagaa acaaacaagg gaaaaaatga
    39721 gattaccaaa agtttatttt tatcaaaaga aacaagaatt agtggtttct tttcctttag
    39781 atggtgggcg ttttcacgaa cgatttttaa aaatgggtca tttgttatct gaagtatttt
    39841 tgcgtgattt aattcgtgaa gaacgagaaa aagcccgaat caattatgta ttcctttcag
    39901 attctggtcg gattcctatt gatcaatgta tagcagaaaa tggacgtatt catttaatga
    39961 aaactttgga ttgggtatat gatcaatcac caaatatgtt gattgctggt gcaatcggtg
    40021 gtgggaaaac ctatttattg tattctttaa ttcaagcttg tttaagtgtt gggacagtag
    40081 atatttgcga tggaaaagcg gcagatttag cagcattagg tgacgtcgat gtattcaaag
    40141 gacatgtgtt ttacaaaata aatgaagaaa tgattatttg tttacgaaat gcattaaaag
    40201 aaatgaatca acggtatgcc tatatgaaaa ccatgaaaga tcctaaatat gaaccaggga
    40261 aaaattatgc ttattatggg ttaccaccgc attttatctt ttttgatgaa tgggcagctt
    40321 tttatggttc gttggatatg gaagcgagaa atagagtcga taaattgatt cagccattag
    40381 tattaaaggg tcgtcaagca gggatgtaca ttattttagc aatgcaacga ccagatgcag
    40441 aatattttcc aagtggtgtt cgggataatt taacattccg tatttctgtt ggtcgattgt
    40501 ctcccattgg ttatttaatg acttttggag aagattttaa aaataagcca ttttacaaca
    40561 aagatcaacc tggtcgtgga tatgcttttc caggatttga tgtacctgta gagttttttg
    40621 cgccatttgt ttacaaagat tatcacttta tcaaagaatt tgagaaattt actgaaatga
    40681 ttgtctatga ttttacagta aaagaggata gtcaagatca aacgatggga gatgataatc
    40741 agttgttaca agaacaacta gagcgccaaa tgtatttagc aaaagatcca aaaggaacaa
    40801 gtttttctga tgcgcatatt ttgtaatcaa ctaaggaggt gaagttaaat ggcagagagt
    40861 tgttattata gagtagctac agcaatacga atgattaatc cttctctttc ttccagaacg
    40921 ttttatgatt ggttgaatcg tattgaacaa gtaactgatt accgcttttt gcgcaaagaa
    40981 cgtgttttta caggaaaagt tattaatcaa gtattgctaa cgaaaaaaga tatagaacga
    41041 ttgactcgat tgtatcatta tcgagtagat ttagaagagg atttaacttt gtcaatttat
    41101 cgcgtttttt ctcctgaaaa atatagtgaa ataacaaaat tagatcattt aattttgtag
    41161 ttattatcta tcgggagggc tctagacgta gtctggtagc cgcactctgc ctggcggtgc
    41221 gcattaaggc tgcgaagcat gggcctataa tgcgcactcg ctagcagcgt gtgcagctca
    41281 caaagaggtc gtgcgcttgc gcacggcctc tttgtgtaaa gccccccgat atataatatg
    41341 gggggcagaa ataacataac acatagaaaa aagttttata aacccttttg tatcaagtga
    41401 ttatctaagg tcagcagttg tactactttt cccaaaaaac gagggggact agttgatata
    41461 tcggtgtttc taaagggtta aaaaaaatcg attttgttat tttataaaag gagcgagaaa
    41521 atgacaccga ttgagctaaa aagctacaga aagaagttaa gtgcaattca taatataagt
    41581 ggagataaaa agccgctatc acaagcaaga tttgcgcaat tgatgggctg ctcaaaagat
    41641 tacattagaa agatggaaca agggaaaaga aaaatcccag aggattttga acaacgaatc
    41701 aaggaacgct ttcgattgta tatgaaaagc ggaatagatc ttcgagcaat gattgattat
    41761 ttgcgtcttt ccttttttgg gacagactac aaaacagtga ttcaacgtgt attacgaatg
    41821 gatctgacag aatttgaaac acgtccaacg ggcttgtatc tttttgactg tctttctgtt
    41881 cgtgggaata tctgggtgtt ctggcattca aaacgaactg taacagaaaa tgtacttgtg
    41941 caattttcag gacaaggttg ccgggaatat gaggaagtca tgcgtgaaca acaaacagat
    42001 tggcgaacat ggctatattc catttggaaa aatcaaggaa agttggaagc tggttataca
    42061 cgtgtgcaat gtagccgatt cgatattgcg ttagatgaac tttggggatt ggaaacggaa
    42121 gaacatttcg atctctttga attactagaa aaacaaaaag caggtttatt agaaatggac
    42181 tttaagagat tccagaatat tggcggttgt tttttagatg atggctattt tcgaagtgaa
    42241 ggattatctt tgtattttgg atcgcgaaag agtcctctct tttttaattt ttatgagaaa
    42301 cgttttgaaa ttgcgaaccg agaaaaaatt tcagaattag aagcattaac gaaatatggt
    42361 atttataatc gatatgagtt acggttagcc aatgagaaag caacacaagc agtagaagca
    42421 tttattttag gtgattcacc gaaacgttta ggagagattg gcgttggttt aattaatgca
    42481 aaacttattg tttgggatag actggaaagt gatgcacgga ttgttgataa acgatgggca
    42541 aaattatttc gttcgatgga agaattggat tttacagtaa agccagaaaa attctcatta
    42601 gatcgttcag aacgctggtt tttgaaacaa gtagctccga cattaaagtt gttacaagaa
    42661 gcagatcgta ttttaggaag agactttgta caagaaggga ttgataatgc cgaactaaat
    42721 gacgagcaac aaaactatct agaatggatg ggaacgtcag gagggaaaat tgcatgaatg
    42781 catatacgac aacagaatgg ctgcgcctgt tggatttaaa ggctgcaatc gaagcattaa
    42841 atgaaaagat ggttgatttg tcttattttc gttttcgagt tccttatatt gaacaagcgg
    42901 taaaagctgg acgttatcag gaaaaagaga actggcaaga aattgcacgc ttattagaag
    42961 ttcgtaaggg atacgaacaa gaactcgaag agttggaatt tagccgaagg aaaggaaggc
    43021 tagaattcat tcgcttttat cgattttcat tgccaatacc tgcgatttta gcggttaaaa
    43081 aaggctgcga taaaatgaag atatatgaaa actgtgtggc agcacttagc agcgaaaaac
    43141 ctcttatgga agaaatttca ttggtgactg tcacttggga aatgagtcgc cagccaacag
    43201 aagaacagac atatctttct ttagaagaga ttgagataga attagaggaa attggtcgct
    43261 atgccacttg ttctacctat tgtggatcgg tcattagtat tgctggtgtg attgtctaaa
    43321 tgaaaaaaat tatgatttat gttggtgcgt attggtcacg tgatccaaca gtattagaaa
    43381 atccagaggc ggtacactat tgcttgcgcc aattattcta tctgtataaa gaacgattag
    43441 aatcgttgat tcgtcagtta ccatatactg acagacgttt agatgaactt cttctaaggt
    43501 atccagcaat gtataaacga cgaaaaaata gattgttacc agaagagtat cccattgaaa
    43561 aacatgaact tgaagggcga tttgtggctt atttctatga tgatgttcgt atgcgcttag
    43621 tagaacaacg aatggaaata gaaaatgatc gctactattt tatcaattat tgtaagaagc
    43681 gtaagtatca agtaactgat gatttttatg attgtatttt acaagatggg gaagtgattc
    43741 tatccaaaat tgctccaagt tttcgtgaac ttgtgccgat tgattttttg aaaaaatgtc
    43801 atttgcggat tcttccgtaa aaaagagcta taaaaggaaa gaaaagtaga agccaaatcg
    43861 gtttctgctt ttttattttt tttaggaagg agaagatggt atgtcactgg aatttttagg
    43921 agagccaatt gaaaaggaag agttcgtttc gcattatatg gatttgttta ttcaggtgat
    43981 aaaaaacttt gtgcgattga tgaattttat ccacgcgaac aagactatct agccgctgaa
    44041 cgaataaaaa tcagtttatt atgggaaaaa ttcacagatg aaaataaccg accgccagat
    44101 tatcgctatt tatcagattg tttaacgaat aatgtgcttt ctaaagaata cctatttcac
    44161 aaacgtgaga aaaatcaaat gtcggttgaa catttttgtg attgttatat tgcattattg
    44221 cgtagtcaac agttattaac agtagaacga tatggtgcag agtttggtta tgtcatgcaa
    44281 gctgagcgtc atagagctac aagatgctat gaaaaagaag atcaagtgat tgatggctat
    44341 gaagaattat gtattcgaaa caatcgctat ttgcaacaac gtttatatga acaattgatg
    44401 atggattttt caaatctcta tagagggtat gaatgttcga tgattcaaga aaggtagaag
    44461 aaaaggggga atttttatgt ggcgattatt atttttggtg gtatgtggta tggcattgtt
    44521 ctatgtgtat cgtgtctatc tctatccacg aatggaacga tggacaagtt ggtatagaga
    44581 tcctttaaaa caacgaaaag gattgaagcg gtatcgttat gaattacttg ttgaattttc
    44641 ggatgggcga caagcacagt attatttttt tgcaaactat ccaaaataca acaccagtga
    44701 actattgatt caattattca aaaataatcc atatgttggg ttagaagaaa acggacggga
    44761 gttcttttat cgttcagata atattagtgc ggcgtctatg aacaaaacac gaattgcata
    44821 aaaaattgga ggaataatca tgaaaaaaac aacattagca gtcgtaacaa cactaggaat
    44881 ttcattattt tcgtttcaat tagggagttc attggtttat gcagatgaaa ctgtagaaac
    44941 acctaagtca gaaattgtag aaacattgcc aggggaagga ttaccagatg ttgagacaga
    45001 gctaaatgga ggaacaacgg aaaaaccagc agaacctgaa caattgcagt cagagaaacc
    45061 tgaaaaagag ccagtgacac cagaaccaga gtttcctgaa tcaactttac cgactgattc
    45121 gatcgaagaa gaaggtgtgc atagttcaac aacaacggat tcaagtatag tcacaactcc
    45181 ggaacaatca ggaacaacca gttcttctga aaagaatact gattcgtcaa gtacggaaca
    45241 gccaacgatg tcgtctacca gtgaagaaca aaaagaagaa ccgaaacaac ctgttgaaaa
    45301 atcagaagca attccaaaag aaaataaacc tattgttcca gcaaaagaag tcacagtatc
    45361 ggtaacccca agcggtgaaa ttacgacgaa tacttctcaa ggaatgagtg taccgattgt
    45421 cactagtaat gtagaggaat tgacccatat tccaacacca accaccccat taaaagtagc
    45481 aggtgatcaa acaattgttg gtgtaaaaga tggtattcca ttaatccaag atagtgaagg
    45541 gaatttggta aaggatttgt cgattcctgt aaagaaactt ccaagtggca atattgaaat
    45601 caaaacagca gatggaaaaa caaaagtctt accaaagact ggtgaagaaa tacatgttgc
    45661 actttctgtt ctaggaggag tgttgacaag tattgctgga tttgttggat ataaaagaaa
    45721 gagaaaagga atagaaaatg agggtaattg aatggactat ttttcagaaa aacaagctta
    45781 tcgttgtcaa tcgtacgtac tagtaaaaac atactagaag gagtagctta tgaaaaaacg
    45841 acaactacgg cggaaagaaa aagtttatac agagaaagta ccgaagcaaa agaaaatcca
    45901 ttcaaaaaaa gcagtgaaat ggatttggtg tttggtttta tttctttgtt tttcaggggg
    45961 cttggcattt tttcaatcca tgaaaacgaa ggttcaagtg tcgtttttga aagatgaaat
    46021 ccaacaatta caaaagaaag aagtacaaag tcggtcagaa ttaacgtaca cacctgaaat
    46081 tgaatccttt atgaatcgtt ttgttgcttt gtatatgaat acattcgata atcatgaaca
    46141 agaacaacaa cgtcaagaaa cattaaaaaa agagttttat gcacaaaact ttattcaaga
    46201 accaggaagt gtttcaggtg ttcgaaaatt aactgctgct tcgtttattg gattaaaaga
    46261 aattgaaacc attccaactg ctagttataa agtaacttat gatattcgct cgatgaatcc
    46321 agagagtaag aaagaaacaa gtgtgacaat cacacaagta ctcaatcttc ccttttctat
    46381 ttcaaacaag ggctgtcgta ttattgctta tccttatttt acggcactac caaagaatac
    46441 agaaaaacaa cgaatgatta cttatgatga cacattatac gaaacggttg atgcgtcgga
    46501 agcgaaagat gttgaaggat ttgtggaaga tttcttagat aagtatgcga aaaacaatgc
    46561 aaaagatatg tcatacatga tgaaagaacc tgaaggactc aatcaaacag ctaaagttga
    46621 tcaagtagag atgaaagtat tgcgttataa agaaacgaaa aaacctttta ttgtaaaagc
    46681 aacggtcgtc tttcgagatg gtgatacgtc acttttacaa aaagaacaaa tgacgattgt
    46741 cattacgaaa aaaacaaatc agtattatgt tgaaaaatta acacataatt ggttggatag
    46801 gaaaggagaa gaacggaaat gacactgaag ggaattgtag attttatatt aacgcaaggt
    46861 ggctattttt taataatggt ggttgtttat ctgggattgc gaaattttat gaaatcaaaa
    46921 gtaggaaatg cattaatatc tatcgcagca ggtgccgcag tttatttctt cttaaatgat
    46981 ccaacacgtg tatttgatgc gtttggtaaa atcattgaaa aattatttat ggattaggag
    47041 gatagtgaag tggattggga accttatgat tattcgattg tttatgcgga accttatcgc
    47101 gtacaacaga ttacaagcaa ttggcgtctt ccatttccag ttgcatta
//
LOCUS       DACGLI010000019        46773 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.020, whole genome shotgun sequence.
ACCESSION   DACGLI010000019 DACGLI010000000
VERSION     DACGLI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.020"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            249..2414
                     /gene="acm"
                     /locus_tag="IXT22_001122"
     CDS             249..2414
                     /gene="acm"
                     /locus_tag="IXT22_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAQ4862502.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2686..3171)
                     /locus_tag="IXT22_001123"
     CDS             complement(2686..3171)
                     /locus_tag="IXT22_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAQ4862503.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            3651..4292
                     /locus_tag="IXT22_001124"
     CDS             3651..4292
                     /locus_tag="IXT22_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4862504.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            4311..4946
                     /locus_tag="IXT22_001125"
     CDS             4311..4946
                     /locus_tag="IXT22_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862505.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4964..5779
                     /locus_tag="IXT22_001126"
     CDS             4964..5779
                     /locus_tag="IXT22_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4862506.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            6098..7534
                     /locus_tag="IXT22_001127"
     CDS             6098..7534
                     /locus_tag="IXT22_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4862507.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7723..10170
                     /locus_tag="IXT22_001128"
     CDS             7723..10170
                     /locus_tag="IXT22_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4862508.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10400..11467
                     /gene="rlmN"
                     /locus_tag="IXT22_001129"
     CDS             10400..11467
                     /gene="rlmN"
                     /locus_tag="IXT22_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4862509.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11660..12763)
                     /locus_tag="IXT22_001130"
     CDS             complement(11660..12763)
                     /locus_tag="IXT22_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4862510.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13316..13864
                     /gene="aac(6')"
                     /locus_tag="IXT22_001131"
     CDS             13316..13864
                     /gene="aac(6')"
                     /locus_tag="IXT22_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4862511.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14409..16070
                     /locus_tag="IXT22_001132"
     CDS             14409..16070
                     /locus_tag="IXT22_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4862512.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(16140..16487)
                     /locus_tag="IXT22_001133"
     CDS             complement(16140..16487)
                     /locus_tag="IXT22_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAQ4862513.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16571..17512
                     /locus_tag="IXT22_001134"
     CDS             16571..17512
                     /locus_tag="IXT22_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862514.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17513..18556
                     /locus_tag="IXT22_001135"
     CDS             17513..18556
                     /locus_tag="IXT22_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862515.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18562..19632
                     /locus_tag="IXT22_001136"
     CDS             18562..19632
                     /locus_tag="IXT22_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862516.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19622..20575
                     /locus_tag="IXT22_001137"
     CDS             19622..20575
                     /locus_tag="IXT22_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862517.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20587..21597
                     /locus_tag="IXT22_001138"
     CDS             20587..21597
                     /locus_tag="IXT22_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4862518.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21882..22703)
                     /locus_tag="IXT22_001139"
     CDS             complement(21882..22703)
                     /locus_tag="IXT22_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4862519.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22800..23078)
                     /locus_tag="IXT22_001140"
     CDS             complement(22800..23078)
                     /locus_tag="IXT22_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862520.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23346..25355
                     /gene="metG"
                     /locus_tag="IXT22_001141"
     CDS             23346..25355
                     /gene="metG"
                     /locus_tag="IXT22_001141"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAQ4862521.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25834..26421)
                     /locus_tag="IXT22_001142"
     CDS             complement(25834..26421)
                     /locus_tag="IXT22_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862522.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26596..27918
                     /locus_tag="IXT22_001143"
     CDS             26596..27918
                     /locus_tag="IXT22_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862523.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            28073..28849
                     /locus_tag="IXT22_001144"
     CDS             28073..28849
                     /locus_tag="IXT22_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4862524.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28842..29411
                     /gene="rnmV"
                     /locus_tag="IXT22_001145"
     CDS             28842..29411
                     /gene="rnmV"
                     /locus_tag="IXT22_001145"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAQ4862525.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29404..30288
                     /gene="rsmA"
                     /locus_tag="IXT22_001146"
     CDS             29404..30288
                     /gene="rsmA"
                     /locus_tag="IXT22_001146"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAQ4862526.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30739..31368
                     /locus_tag="IXT22_001147"
     CDS             30739..31368
                     /locus_tag="IXT22_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862527.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESVQGYAKKTTY"
     gene            complement(31491..32600)
                     /gene="ugpC"
                     /locus_tag="IXT22_001148"
     CDS             complement(31491..32600)
                     /gene="ugpC"
                     /locus_tag="IXT22_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAQ4862528.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32809..33231
                     /gene="mgsA"
                     /locus_tag="IXT22_001149"
     CDS             32809..33231
                     /gene="mgsA"
                     /locus_tag="IXT22_001149"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAQ4862529.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33554..34090
                     /locus_tag="IXT22_001150"
     CDS             33554..34090
                     /locus_tag="IXT22_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4862530.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(34130..35893)
                     /locus_tag="IXT22_001151"
     CDS             complement(34130..35893)
                     /locus_tag="IXT22_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862531.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35896..37611)
                     /locus_tag="IXT22_001152"
     CDS             complement(35896..37611)
                     /locus_tag="IXT22_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862532.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38390..38614)
                     /locus_tag="IXT22_001153"
     CDS             complement(38390..38614)
                     /locus_tag="IXT22_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862533.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38814..41582
                     /locus_tag="IXT22_001154"
     CDS             38814..41582
                     /locus_tag="IXT22_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4862534.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            41663..42082
                     /locus_tag="IXT22_001155"
     CDS             41663..42082
                     /locus_tag="IXT22_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAQ4862535.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            42094..42564
                     /locus_tag="IXT22_001156"
     CDS             42094..42564
                     /locus_tag="IXT22_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4862536.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            42581..43360
                     /locus_tag="IXT22_001157"
     CDS             42581..43360
                     /locus_tag="IXT22_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4862537.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            43347..44168
                     /locus_tag="IXT22_001158"
     CDS             43347..44168
                     /locus_tag="IXT22_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4862538.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            44185..45234
                     /locus_tag="IXT22_001159"
     CDS             44185..45234
                     /locus_tag="IXT22_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4862539.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            45247..46251
                     /locus_tag="IXT22_001160"
     CDS             45247..46251
                     /locus_tag="IXT22_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4862540.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        15486 a         8135 c         9630 g        13522 t
ORIGIN      
        1 aaatatagat tgaaaaaatg aaagcaataa gtaaaataaa atgaatatat gcgaaaaaat
       61 aatttacatt aggaaaaacc ttgtaaaaac agttttttgg catatttatt ttttataaat
      121 atttgtaaaa taactatcaa ttttttagtt aaaagattgg aaatgagtgg gggaggaatt
      181 gaagaaagga tttttgagag atgatatagt aggttttatt tttagttaaa ataggggaga
      241 tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat gttatttatt attactaata
      301 taacatcact gattcctgtt catgtctatg cggatgcagg cagagatatc agcagtaatg
      361 tcacttcgtt gaccgtggac ccaacgaata ttacagatgg aggaaacata aaagtaaaat
      421 tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga ttatctttgg atcaattggc
      481 caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga aatcccatta atgattgaaa
      541 ataaaaatgt tggaacttta acggtcagaa aagattctgc gcaggttgtg tttaatgaaa
      601 atattaaaaa cctagactca gtagaaggtt gggggcaatt tgagatacag gccagaaacg
      661 taaccgatac cggtgaagaa aatacgggac cattcaccgt gacgagcggt gataaaacag
      721 ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc tagcgttttt tattataaaa
      781 caggagacat gctacctgaa gatactaagc acattcgatg gtttttgaat attaacaata
      841 acggcactta tgttgaacaa ccagttaaaa tcagtgatga aatccaaagt ggacaaagat
      901 tagatccaag tacgtttgaa attaatcaaa tacacttagg tgaacagaag gtttatagag
      961 gagaagaggg aatccaacaa tttttacaag atttccccag cgctacattt aatttttcag
     1021 taactgataa ttacattgaa ataactatac caaaaaactt tgtcaatctt aggaaaataa
     1081 tggtgagtta taagacgatc atagaaaacc cagaacaaat aaattttgag aatcattcgg
     1141 aagcttggtt taaagaattt aataaacctg ctgttgatgg agaaagtttc aatcatacag
     1201 ttaaaaatat ttcagcttct ggtggagtca acggtacagt tagaggcgaa ttgaagattt
     1261 tcaaatatat caatgacaca gagattggta tcccaaatgt gactttcgaa ttaagacgag
     1321 cagatgaaca gcctattcaa ggacagtcta gtatcctgtt gacttcgaat gaacagggag
     1381 aagctagtat caaaggcctg caagtaggag actatgttgt aaaagaaaaa gaagcaccca
     1441 attggattga ttttgatcca ctaagttcaa atgaactcaa attctccata aacgaaaatg
     1501 atacagaggg agtcagttta cctatttata acaagaaaaa ggttacgaac atcacagcaa
     1561 ctaaaatttg gaacggtgga accactccaa gaccgagtat ttattttaaa ttattcagag
     1621 caagtacaaa caattgggaa ccagttcctg atgcagaaac aaaacgatta gacaatggaa
     1681 taacttcagt gacttgggaa gatatccaac agtatgatga tagtggaaac gaatatacgt
     1741 ttaaagtgca agaagtagat caaaacggaa atgattatgt cccttcaggt tatcaaaaaa
     1801 ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt catttcagtc tcaggacaaa
     1861 aaacatggga agacaatgag aaccaagacg gcaaacgacc gacgacgatc acagtaaatc
     1921 tattagccga cggtcaaccg atccaacaca aagaagtaag tgaaaaagat gattggcgct
     1981 atcgtttcac aaatctgcca aaatacagag acgggcaaga aatcatctat actgtaacgg
     2041 aagacaacgt gcccgaatac agtacgacga ttgacgggta taacatcaaa aacagttata
     2101 caccggaaaa aacaaatata tctataccag gtagccatat aacaccgtgg aaaaattttc
     2161 cagagaagac agagagagag aaaattagaa atctattctc tcaaaaattg caaatatttg
     2221 ctcatacagg agaatccagc gaacaaagaa gcaattatat tagtaagaga gctgtaccta
     2281 aacagataac aaataaatca aaaagcattc ttcctaaaac aagtagtaaa aaatctagtt
     2341 ttgctgtaat cattggttta ttgatagtaa ctatctgtgc tgggatattc ttacaaaaat
     2401 ataaaaaagt ttagttagaa tataatattt tttgttaaat atgactgaaa tcaaaagaat
     2461 aaaattccga tttataatcg aaaaaagaag catttttata tatgcttctt ttttcgtaga
     2521 atcaataaat atggatttgg ctaactatgg aagaatactc gtattagttt tcagcgttca
     2581 tactagttgt tacattgttt gattggccaa aagaatttct gatatatttt gtgctaaata
     2641 aagaaaaaga cgcttgaatt gggaaataag aaaactactc tatcattaca aattttcata
     2701 aactggcaga tgttctaagt aaacaagtat cttttcaaag tcggaaaaat ccataatcaa
     2761 cgtagtggta ttgatatttg gatgaaagcc tacggtatct tgacgatcaa tagcagcatc
     2821 gatcacgact tggatttttt tctctttgtc gtgcatcaat gctaatggag tcactgtacc
     2881 tgctggaacg cctaggaggt caggaagctg ttcttcagaa acaaaagata agcgcttttc
     2941 ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt tcatcaggca agatgacaag
     3001 atagatttgt tttccttttc ttgatttcaa taatagattt tttacttgcg gaccaggtag
     3061 ggaaaaaggg acatttttga ctgacgtaat cgcaggatga tcgacttttt gaaaagagat
     3121 acccagtttt tttagtagtt cataagcttc ttgttcggtt gcacgactca tcgcgcatca
     3181 ccctcctttt tttattagtg tatcataaaa aagagttgac aaatgaaaaa taatcatgta
     3241 aattacacgt aaagttaaaa caaatgacat cgaaaagaag agtagccgtt aggtgttttt
     3301 agagagtctc tggttggtgg aaagaggcag cagttaaccg tgaaacacat cttggagtcg
     3361 attttctgaa gcgtatagta ggaaaatccg gggagcccgt tacagctgcg gtcgttgcta
     3421 gatgaccaga taaggctggc ttttccgtga ggagtcggta aaaaaaggtg gaaccacgtg
     3481 attaacgtcc tttgatcttc ggatcaaagg actttttgtt ttcatctgaa cggcaacgac
     3541 tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt ggaaccacgt ataatacgtc
     3601 ctcttggcat ttgccaagag gattttttta ttttaaagga ggaaaagaag atggagtatt
     3661 tgattgaagt tatgccgcaa ttattagtag gagcactcac aacattgaaa ttatttttat
     3721 ttaccttgat tggctcatta ccattaggga ttgttttagc attaggattg tctttgcatt
     3781 ttaagccgct acgctacttg cttcaaacat atgtatgggt tatgcgggga acaccgctgt
     3841 tgttgcaact gatttttatt ttttatgggt tgccgacgat tgggatcgtt tttgatcgtt
     3901 tcgaagcagc actcattgcc tttatcttaa actatgcagc ttattttgca gagatctttc
     3961 gtggagggat acaatcgatt cctcaaggtc aatatgaagc agcgcaagtt ttgcaattaa
     4021 gtccctttca aacggtgacg aaaatcgtca tcccacaagt gacaaagatt gttttacctt
     4081 ctgtagggaa tgaagttatc aacttggtca aagattcttc cttgatctat atattaggtt
     4141 taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg cgacgcgact ttactgcctt
     4201 tgctaggcgt ggcaatcatc tatcttacat tgactggtat tctaacaatc ataatgaaac
     4261 aagttgaagg aaaattaaat tattaccgct aactgatagg aggaagaaat atgattgaat
     4321 tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat caaagatttg aatctaatca
     4381 ttccagatgg gaaaacatta gctatcgtag gtccttccgg tggcggtaaa accacgcttt
     4441 tacgtatctt ggctggctta gaaagttctg acagcggaga attttattta gacggtgtac
     4501 cgttcaaccc attcgagctt aaaatgaaag aacaagttgt aggagtcgta ttccaagact
     4561 tccagctatt tccacatctg aatatttttg aaaacattac cttagcacca aaaatggtat
     4621 tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga attagcggct tcattaggga
     4681 ttagtgattt attgaatatc tatccttatc agctttctgg cggacaaaaa cagcgggtag
     4741 cgattgccag agcattggct atgaatccac gggtattggc ttatgatgaa ccaacaagtg
     4801 ctttagatcc tgaattacgc cagcaagtcg agcgtttgat cctatcattg aaagaagatg
     4861 gggtaaccca aattattgtc acccatgatt tagtatttgc agaaaatgtc ggtgatcaat
     4921 tactaaaagt ttccccaatt cattaagaaa ggagaagata gagatgaaaa aaaccagttt
     4981 tctattcgct ttgatcgcag gtcttcttct ttttgcaggc tgttcgaaca aaaaaacttc
     5041 agcagataat tgggcgacta tcaacgaaga gaaaaaaatc gttataggtt tagacgatac
     5101 atttgttcct atgggattta gagataaaga cgggaagctc acaggatttg atattgattt
     5161 agccaaagca gtctttgaac aatatgggat tacggtagac tttcagccca ttgactggtc
     5221 aatgaaggaa tttgaactga acaatggaac gatcgatttg atatggaacg gctattccaa
     5281 aacgccggca agagaaaaga aagtgcaatt tacaaaacct tatatggaaa acgatcaagt
     5341 gctgatcaca cctaaagaat caggaatcac aaactttgga caaatgaata ataagagatt
     5401 aggtgcgcaa aatgggtcat ctggttatga tgtatttacg aaacaaccag aagtattaaa
     5461 agagatagtc aaaaaccaag atgctgtttt gtatgatagt tttaatgaag cattgatcga
     5521 tctgaaaagc agacgggtcg atggtctgct gatggataaa gtatacgcag actattattt
     5581 gaaacaaaga aacgaactag aagacttcaa cataacaaaa ggttcttatg agagtgagga
     5641 ttttgcagtt ggtgcacgca agtcagatag tacattagtg aaaaaaatca atgaagccct
     5701 agatcaacta gagaaaacag gtgaattcca aaaaatatcc gataaatggt ttggcgaaga
     5761 tgttacgccg agaaattaac aaatagggga ctgtgacaaa agacgtgtca cagtcccttt
     5821 ttccgaataa acagtgttct cctgccaact ccttgtgact cggagctgaa tggcaggctc
     5881 acaacctctt ggtaaacggt gttcaaaagc cagtttttcg gtattaagcc aaatttatgc
     5941 aaaaatgtag aaagccattt tcacaaaatt tttcttacta ctcgaaacta agcgactttt
     6001 tcacaacctc ctttacataa ttttattttg ttgtggaagg ggtttcgtgt tattctaaaa
     6061 gaggaacgat tgaaggttat aggaaaggaa gagatgaatg gaacacaaag aacttacctc
     6121 atttccaaaa gattttctgt ggggctctgc ttctgcagcg tatcaagtag aaggagcttg
     6181 gcaagaagat gggaaaggag aatcagtctg ggatcgattt gtacggatac ctggaaagac
     6241 atttaaagga acgaacggtg atttggcagt agaccactat catcgttata aagaagatat
     6301 tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc tctgtagctt ggacacggat
     6361 ttttcctaat ggacgaggag aagtcaatca agctgggctc gctttttatg agagattgat
     6421 cgacgaattg attgaaaacg atattgaacc tatgttgact ttatatcatt gggatcttcc
     6481 acaagcattg caagatgaat ataatggttg ggaatcacgt cagatcattg aagatttcac
     6541 tcattatgca gaaacattat ttgaggcatt ccgcgggaaa gtccattact ggattagttt
     6601 gaatgaacaa aatatcttca cttcattagg ttatttgtta gcagcacatc cgccaggtgt
     6661 gacagacccg aaacgaatgt atgaagttaa ccatattgct aatttagcaa atgcatctgt
     6721 catcaataaa tttcacgagt tagaaatgcc tggaaaaatc ggaccaagct ttgcgtatac
     6781 gccaaattat ccaattgaca gtaatcctga aaatgttctg gctgctgaaa atgcagaaga
     6841 cctgatggcc aattattgga tggatgtcta tatgtgggga aaatatccga ttgctgccat
     6901 gaggttctta gaagaaaaag gatgggcacc aacgattgaa gctggcgatg cagaattgct
     6961 agaatctgct aaaccagatt ttcttgggat caattactat caaacggcga cgaatgcatt
     7021 caatccatta aacggagttg gtgctggaaa aatgaatacg acaggaaaaa aaggttcatc
     7081 agaagaaact ggagttcctg gaatgtataa aaaagttgag aatccatttg tcgaacgaac
     7141 aaattgggac tgggagattg acccagaagg attaaggatc ggactgcgtc gtatcacaag
     7201 ccgttaccgc atgccggtac tgattacgga aaatggctta ggagagtatg acaagttgac
     7261 agaagataaa caaatccatg acgactatcg aatcaattac ttacaaagcc acgtcaaagc
     7321 catcaaagaa gcaatttcgg atggagcaga agtcctaggc tattgcacct ggtcttatac
     7381 agatttgctt agctggctga acggttatca aaagcgatat ggatttgtat atgttgatca
     7441 agacgaaaca caagaaggat ctttggaacg atataagaaa gacagttatt actggtacca
     7501 aaaactgatt gaagaaaatg gagagaacct ttagttcaca tacttaaaac aagaaggtac
     7561 ggctggatat ggccgtgcct tttcttgata aaatcattta gaaattaaga aaaactgtaa
     7621 aataagctga aaaatgaaag aaagcgtcag ttctttcaaa caaaacttta gttcccttac
     7681 ttttttttgt ataatgaaac ttgatgaaat gagggataat aaatggcaca aaagaaacgg
     7741 cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc aaaaacagca gcaggaacaa
     7801 atgctgacga ttggtgttgg gtttgccttg attttatttg ctgtcttcgg ctttttaaaa
     7861 ttaggttttt taggaatatt gattgcaaac ggctttcgga tcattgcagg aaatacttac
     7921 caaatcctct gtcttttatt agccgtatta ggattttgga ttgtcattaa gaatacagag
     7981 ttttcaattg gtaaaaaccg acgctggttt ggcggcatac tcttttattt cggtatctta
     8041 ttattgttac atgcccattt atttggcaaa ctccatactg gggaaccaaa tatcatgggg
     8101 acgacatggg atttgttagc cagtgatata aaacaaagtc aagtagacaa taacgttggt
     8161 ggtgggatga ttggagcaat cctttatcat tttacttact tcttgattgc acagcctgga
     8221 agttatttag cagcagtgct attactggca ggaggagcat tcctgttcag taatctggaa
     8281 ggctatcagc tgttaaatgg tatccaatca attggagaac gagtacagga attattggaa
     8341 ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg aagagagaat gaaacagcgc
     8401 gcagaagcga aagaagcaag gcgcttagct gcaaaagaag ctgcagaaaa agaagctgca
     8461 gaatatgaga agaaaaaagc ggtgagccag caaagggaaa atactgctga tgaatggcag
     8521 gaaccagaaa atacagagcc ggagcagcta agttttgttc caatcgacag ttttcaagaa
     8581 aatatccatc ctgcgaatct agagaaacca gtaccagata caccaaaaca gaccaataca
     8641 gcagaaggtt tttcagatga gttgccagag gatgacggta cctcattaga atttgagatt
     8701 gaagcagaac aggaaaatca agactatgaa ttaccgacag ttgatttgct tgattctata
     8761 ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa aaaatatcgg cgtattagaa
     8821 caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca aagccagctt aggaccatcc
     8881 gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag taagtaaaat tgtgaactta
     8941 acagatgata tcgcgcttgc tttagcggcg aaagatgtcc ggatggaagc accgattcca
     9001 ggtaaatcac tgattggtat tgaagtacca aatggaaaga tcagtatggt ttcctttaga
     9061 gaaatcatcg aagcacaacc aaaccaccca gataaattac tagaagtacc tttaggacgt
     9121 gatgtttctg gacgggtaca aacggctgat ctttcgaaga tgcctcactt actcgtggct
     9181 ggttcgactg gtagtgggaa gtcagtagca attaatggga ttatcacaag tatattaatg
     9241 cgtgctaagc cccatgaagt aaaactgatg atgatcgatc cgaaaatggt tgaattgaat
     9301 atgtacaacg gcatacctca tctgttgacg ccggtcgtga cgaaccctag aaaagcagcg
     9361 caagccttac aaaaagtagt acaagaaatg gaagaacgat atgaaaaatt cgcggcaacc
     9421 ggagtaagaa atatttctgg ttacaatgaa tttgttcaac agaaaaactt ggaaaacgga
     9481 acgaaacatc caaccttacc attcatcgta gtgatcgtag atgaattagc tgatttgatg
     9541 atggtagcca gcaatgaagt tgaagatgcg attattcgtt tagcgcaaat ggctcgggca
     9601 gcggggattc atatgatcct agctactcaa cgtccaagtg tggatgttat cacaggaatc
     9661 atcaaagcaa atgtaccttc cagaatggca tttgcggtat caagcggtac agattctcgg
     9721 acgatcattg attctaatgg ggcagaaaag ctcttagggc gaggagatat gctattcttg
     9781 ccaatgggtg agaataaacc gatccgtgtg caaggagcat tcatttctga ccacgaagta
     9841 gaacgggtcg ttcaatttgt tacagatcag caagaagctc attatgaaga gaaaatgatg
     9901 ccgacagatg aagttgaaac gacaggtgct ccagaacagc cacaagatga gctgtttgaa
     9961 gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta tttcccttct ccaaagaaga
    10021 tttcggatcg gttacaaccg agcagcacgt ttagtagatg aactggaagc tcatggagtt
    10081 gttggcccgt cagaaggaag caagcctcgg aaagtattca ttgagcagga agaaacatca
    10141 gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg atgaagggtt gaaaaacgaa
    10201 taaccaataa aaagacaagg catgatgata ccaaaagaaa aaatggtttt tttccatctt
    10261 ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg agattaaagt tctattcgat
    10321 ttatttgtga agtattgcat taaggaaatg aatcatgtat agtatgtagc gaaactttga
    10381 gaaaaagagg gaaaatactt tggaaaaaca gtccatttat ggcttgacga atgaagaatt
    10441 aatcaattgg tttatagaaa acggcgagaa aaaattccga gctgcccaag tttgggaatg
    10501 gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg aatctatcga aacaattgat
    10561 cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa cagatggtcg tccaagaagc
    10621 ttcggatggt acagtaaaat atttgtttga actccctgat aaaaacatga ttgagactgt
    10681 actgatgaga caagaatatg gcttgtcagt ttgtgtgacg acacaagtag gatgtaatat
    10741 cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac cgtgatctga ctgctggaga
    10801 aattgttgca cagatcatga tggtccaaca ttattttgat gagcgcaatc ttggcgaacg
    10861 cgtttcacat gtcgttgtaa tggggatcgg tgagccattt gataattacg acaatgtaat
    10921 ggactttttg catatcatca atgatgccaa aggattggca attggtgctc ggcacattac
    10981 agtttccact agtggattag cacacaaaat caaggaattc gctaataacg gcttgcaagt
    11041 caatctggct atttccttgc acgcgccgaa taatgaggtg cgaacatcga tcatgcggat
    11101 caaccgaagt ttcccaattg agaaattgat ggaagctgtg gatgagtatt tagagaaaac
    11161 aaaccgtcga atcacgtttg aatatatcat gttgaatcaa gtaaatgata gaccagagca
    11221 tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa ttagcatatg tcaacttgat
    11281 tccatataat ccagtcagtg aacatgatca atattctcgc agtccaaaag ctgatgtatt
    11341 gagattttat gatgtattga agaaaaacgg cgtaaactgt gtgatacgta aagaacatgg
    11401 tacagatatt gatgcagctt gcggacaatt gcgaagcaag caaatgaaaa aaacagttgc
    11461 caaataatcg tatcctactc gttttttcaa ttaccataaa aggagcagtt ttcttaatta
    11521 aggaactgtt caacttaaat aagagaaaag attctatagc gaaagctata aagctttttt
    11581 tgacaagaaa aaccctcatc aagcaaagaa atgtcctcaa tttgatgaca gcctgcttga
    11641 tgggggtttt agcaattatt taactgattt tcttatatcc ttgctggctt tcttgtgtag
    11701 catgataagt ttctacgtca agaatggcct gtttaaattt ttctcgggtg atttcataag
    11761 gcacatgttt aatatcattt gttgccatgg ctttatctaa gattgcttct aaatcggtcg
    11821 tgacattgag attcatgtcg gttaacgata ctggaagttg gttctttttc ataaacacat
    11881 agattttatc aaacaaatcg aactgctgat ccatcatcaa taaggtcagt acaccataac
    11941 tgacagatgc tccgtgaagg tatccctcca ttttttctag aacagtcgta ccgtaataga
    12001 atgagtgtgc catagcagaa ttatagttat tgttaactaa aacagaaacc aatccggtag
    12061 taacaatgat atccgaaacg acttgttcaa ttgcatatga gggacgatcg tcggcactat
    12121 ctttcaatgc ttgcgtacca taagtcaaga gacgatcaat gcacattttt ccgatttgga
    12181 ttcctaatct atccgtgtag cctagatcat cgccacgagc agaaaaagta gattcgactt
    12241 ctttggataa agcatcgcca atacctgccc ataagtattt atcaggtgct tcggcaataa
    12301 ttgctgtatc aatgaaggtg tgtacaggtg gttttgaagg aaagaagagt ccgtccatta
    12361 cgccttcttc gttatagatg acacataccg cagtgacggg cgaacagttc gaaccaatag
    12421 tgggaaaggt gaagactggt ttagctagtt tttcaccaat gacttttaca gtatcgcaag
    12481 cacggccacc accgactgca aacaggacgt ctgctttttg gacactttca tgctggatca
    12541 actgttcaat atttccataa gttgaattac ccccgtacca gagactggcg acaacctcta
    12601 tttcctgtgt caaagctact tttattttgt tttctgcctt tgaaagtgca gtcttccctc
    12661 caatcagcac tacttttgtc ccatattctt tgacgattcc atttgctttt tcatacgcat
    12721 ctgttccaat ggtataattt ggtaagaaaa cactttgact catattcatt tccttctttc
    12781 ttcgttgaaa cgggttaaaa ttttaaagag tgatcgatct gactgcggct gtagatggag
    12841 tagaggtgaa cctaagacag gataagtgat gaataaggtg gcatgaacac cttgaaatca
    12901 tcaataagta tcctaaaaac gaacaagtac aaaaacattg aaaacgacaa taatgaattt
    12961 ttgttcctct tagtatttct accgattccc tttgcttttt tgtaattatc taaaaattct
    13021 aaaaattaag attattatat gaaaacaggt tttatttgtc aattcataat tggttttttt
    13081 taaagcaaaa gataatctat atcatgatga acaaacagag ttttttcctc caattgatgg
    13141 ctttcctgat ctttcctatt ttgaataaag tgtttctgta taattttttt attttataag
    13201 taagataaat aatgaaagaa tagagatact gattggtagc taaagatttt tgagcgagaa
    13261 catttcgttt tttcaaaagg actgttagaa taagcaagaa caagggggaa gacgtatgat
    13321 aatcagtgaa tttgaccgta ataatccagt attgaaagat cagctttctg atttactgag
    13381 actgacttgg ccggaagaat atggagacag ctcggcagaa gaagtagaag aaatgatgaa
    13441 tccagaacga atcgcggtag cagcggtaga ccaagatgag ttagtaggat ttattggtgc
    13501 aatccctcaa tacggtatca caggttggga attgcatcca ttagttgtag aaagctcccg
    13561 acgaaagaac caaataggta ctcgattagt caattactta gaaaaagaag tagcttccag
    13621 aggaggaatc acgatttatt taggtacgga tgatttagac catggaacaa cgttaagtca
    13681 aacggacctg tatgagcata catttgataa agtggcttcc atccagaacc ttcgtgaaca
    13741 tccgtatgaa ttctatgaaa aattaggtta taaaatcgta ggtgtcttac caaatgcaaa
    13801 tggctgggac aaaccggata tttggatggc aaaaacgatt attcctcgac caaattctca
    13861 ataataaaaa gaggttgtga cagaagtaat cagcttcaag aaataagaag gaatttacga
    13921 aaattacttc ttgaattttt gtgaaattcc aacttatttc cgaagaagct acttttggaa
    13981 caccgtgtac cagaggttgt gaaaaagtcg ctagtttcga gtagtaagaa aaattttgtg
    14041 aaaatggctt tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa
    14101 caccgtttat tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat
    14161 tcttttttat ctttgtatgg caataataga caatataacg aaaattattt aatggctttt
    14221 ggaagaccat ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca
    14281 cgaaaaaatc attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt
    14341 cattaaactc ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg
    14401 tacgtaaaat gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg
    14461 ctggatgtta tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag
    14521 atggaggagg cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag
    14581 ttgcaacaga tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc
    14641 ttgatgaaga cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag
    14701 acggattaac ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg
    14761 ttacagcagc ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg
    14821 aatatgctta cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag
    14881 ataaatcaga actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga
    14941 aacaaacacc atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat
    15001 ccgtagtgga agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg
    15061 gaccattcac attagaagat tttgatggac caggaacaga tacagaatgg acttataaga
    15121 aaaatgatca ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag
    15181 taaaagaatc ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct
    15241 tgtctggtga gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag
    15301 cgcggacaag ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga
    15361 acctaagaaa agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag
    15421 gtgacggatc agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa
    15481 cgaacgaaga ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa
    15541 aagaatattg ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga
    15601 tggcttctga tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag
    15661 aaaacttgga tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc
    15721 gctcaacttc gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc
    15781 caagcagctt tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca
    15841 atgcagaata tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag
    15901 cccgttggga tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc
    15961 cggtgtacca aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc
    16021 atgcggcagg cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac
    16081 cgtgagcatg agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact
    16141 tatcctaaca aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg
    16201 atcagccaaa agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt
    16261 ttctttcggt tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc
    16321 gaagaaaaga cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga
    16381 tcattagata attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc
    16441 agaatcagta gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt
    16501 tatttttggt tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg
    16561 ggaaacatta gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat
    16621 cacgctttgg ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc
    16681 atatacgaat caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg
    16741 tttggataaa ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga
    16801 ttttggaatt tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat
    16861 cggaccatcc ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat
    16921 tttaggaacg atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt
    16981 agcgatatta ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt
    17041 tgcaatcaaa ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt
    17101 accaacaatt gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga
    17161 aatggtggaa gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg
    17221 ttgggaaatc gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt
    17281 aggaccgtta gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat
    17341 tcctggtatc ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat
    17401 ggctgtaacg atcctttact catttatgct gatttttgtt attttgatcg tggatctatt
    17461 gtacggtcta gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat
    17521 gataccaaag cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca
    17581 aaaaaatacc gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga
    17641 ttcatggcgc cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt
    17701 catcattttg atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa
    17761 cgtggcttat atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg
    17821 aaaagcaatg gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa
    17881 cgtaaatttc tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat
    17941 gggaatgaga atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg
    18001 tgtagcttac gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg
    18061 ttttttggaa atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt
    18121 ttttgaacca ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat
    18181 ggcacgtatc gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg
    18241 attgacatta ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc
    18301 tagtgtcatt attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt
    18361 tttaagcttt atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag
    18421 cgaagggtac aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt
    18481 atcggttatc atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc
    18541 taaaatgaaa gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct
    18601 tttgatacgt atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa
    18661 ggagaaacat tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc
    18721 atcatgcgct tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt
    18781 aacgatatcg ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg
    18841 atgattttcc aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc
    18901 gctgagtccc ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta
    18961 gaattgctta aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat
    19021 cagttctcag gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg
    19081 gaaatcctga ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt
    19141 ttggagctgc tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat
    19201 gaccttggtg tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc
    19261 gttgaagttg gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga
    19321 ctgcttggtt caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt
    19381 tctccaccgg atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc
    19441 gcgatgaaaa tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag
    19501 gcagcaactt ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa
    19561 cgtcgctggg ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct
    19621 gatgccaaat aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa
    19681 gaatgaagta catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg
    19741 tttagttgga gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa
    19801 tgaacctact gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa
    19861 aaaaggtttg acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc
    19921 gttgaatcct cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact
    19981 agctaaatca tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt
    20041 gaatccaagc cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat
    20101 tggtattgca cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc
    20161 tgcactagat gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga
    20221 acatcaattg acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga
    20281 ccgaatcggt gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta
    20341 taatcacggt gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc
    20401 agaccatgag agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt
    20461 acgtcaactt cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc
    20521 atattacgca aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg
    20581 acatagatgc taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa
    20641 ttgattcgta cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag
    20701 aaaagttggc aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa
    20761 gaatacccat tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg
    20821 gatcgggctt ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa
    20881 aaaagtatgt ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat
    20941 ggctacttaa agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt
    21001 gaaggatcga ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca
    21061 ctactttgtg atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc
    21121 tatcatccga agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt
    21181 caccagacag aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc
    21241 gctcaccata gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa
    21301 gtaatggatc tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct
    21361 gggaaattgg tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca
    21421 catgctgatt tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc
    21481 caatggtata ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc
    21541 gtaagaaaga gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa
    21601 atgaatgaaa ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt
    21661 ttgtttctag gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac
    21721 aatagcagaa aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt
    21781 ttacgaatac atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt
    21841 tttttcttga atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc
    21901 ttgagctgat agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg
    21961 aaatattgga gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct
    22021 aagaatttag caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt
    22081 agaacttgcg gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt
    22141 tgactatggt caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc
    22201 gagatagcca cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac
    22261 cagcgtactt ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag
    22321 tagctgactg tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt
    22381 tgctcaatat tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg
    22441 ctttctccag ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga
    22501 taaggatgcc cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag
    22561 cacatcagta cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt
    22621 tgataccagt taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct
    22681 tctttagaag caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc
    22741 ttattgtagc agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt
    22801 taaatatgaa aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc
    22861 aatactttat accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca
    22921 atgataaaac gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta
    22981 aaataaccat acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa
    23041 gcaatactaa gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa
    23101 gatagatagt ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag
    23161 atatgaaaca aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat
    23221 tgaacgtaga tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat
    23281 gcttttttta tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga
    23341 gccccgtggc agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca
    23401 aacttcatat cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac
    23461 ggttgatggg ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg
    23521 aaacaaaagc agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg
    23581 atgtcaagaa attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag
    23641 atgattacca taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata
    23701 tttacttagg tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa
    23761 cacaacttgc agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa
    23821 gtggacacga agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg
    23881 cagaccgtct attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta
    23941 aaaacgaaat gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa
    24001 caacttttac ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga
    24061 tcgatgcatt atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat
    24121 tcgaaaaata ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata
    24181 cgatctattg gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg
    24241 ggcatggctg gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt
    24301 atcctgaaat gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg
    24361 ctgttccgtt tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt
    24421 atgatctggc aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat
    24481 attgtgatgg actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt
    24541 ctacgacggc tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca
    24601 atacagcatt ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa
    24661 cagaaccatg ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga
    24721 tccatttagc tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa
    24781 cgccagagaa gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat
    24841 tacactttgg cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc
    24901 cacgtttaga tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc
    24961 aaacaaacga agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag
    25021 aaaaacaaat caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca
    25081 actgtcaaaa agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca
    25141 gccaagaccg tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga
    25201 tcgggaaaaa agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca
    25261 gtcaaggaat gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac
    25321 caaaatccat gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag
    25381 ttgtgtcata cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    25441 acttgaagcc aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa
    25501 gaagtacgag cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa
    25561 cagaaaaaaa gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct
    25621 tttttattgt ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta
    25681 tatctaacag tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt
    25741 tgtgctctta tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc
    25801 gatgattgtt ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat
    25861 ttttgtcttc aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac
    25921 ataccagaaa atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg
    25981 taacaagatc aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat
    26041 gacttcacta agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt
    26101 catccgccag ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa
    26161 aataccgata ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat
    26221 cacaggacct ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg
    26281 tgataacgtt gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga
    26341 ctgctgttgt tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg
    26401 ataagaacgc ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata
    26461 cgaaaaataa aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa
    26521 aaaagaatgg taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga
    26581 agaaagagga tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta
    26641 gctaccgtta tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact
    26701 gctagtactc agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg
    26761 atctgtgctg gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct
    26821 gtaaaatata ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa
    26881 agcttgattt actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg
    26941 acgaacttat tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt
    27001 tctgtgacag ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg
    27061 ttgattgtta aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga
    27121 caaggaactg tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga
    27181 ttgagcagtg cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca
    27241 atggcagggg aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg
    27301 agttttgtaa cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt
    27361 gatcatcttg ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga
    27421 atcggtggaa agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt
    27481 tatacactaa ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc
    27541 agtaaacagc tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc
    27601 cagttagcag tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg
    27661 ttgatttttg tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga
    27721 aaaaaagcgc cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt
    27781 attgcgattc tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta
    27841 gcattgatcg gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa
    27901 aaacgctcag aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc
    27961 tagatcttcg tgctttttct atttcaataa aacaagttct tctattttga tttttgctac
    28021 ttctgcaagt agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt
    28081 tgattctcat acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca
    28141 gcgagcacaa gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat
    28201 tgaaaagtct ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca
    28261 tccgacagag gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac
    28321 tttaccaaag gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc
    28381 gaaagaagtc caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct
    28441 accaatcagt attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga
    28501 agatgttcga gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa
    28561 acgatttctt gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc
    28621 attagacgtc caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga
    28681 tgccccttat ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg
    28741 ttatacagta gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca
    28801 aacatggaca aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc
    28861 aagagattat agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg
    28921 cagatacgat agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac
    28981 atgcccaaga gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa
    29041 taagaaaaat cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac
    29101 aagctaaacc aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt
    29161 tagaagcatt gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca
    29221 ctagacaaga ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag
    29281 aaaaactagg tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt
    29341 tgaagatgtt tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac
    29401 aacatgagtg aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa
    29461 catggttttt catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta
    29521 aggaaaatcg tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca
    29581 ggaatcggtg cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag
    29641 atcgatgatc gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact
    29701 attgtacatc aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat
    29761 gaggagcttc cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg
    29821 atgcattttc ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa
    29881 gtagctgatc gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct
    29941 gttcaatatt atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct
    30001 cagccaaatg tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa
    30061 gtgacagacg aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa
    30121 acgctttgga ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta
    30181 gcaaaaagct tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta
    30241 caagaattcg ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg
    30301 tgacagaagt tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata
    30361 gttcctcatg tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg
    30421 tttaagaaag aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa
    30481 aacagcttct catgtttttg agttagttgg tcttattact tgatgcaagc tcttgaccac
    30541 tattatgccg aacaaggaga cgtgacacaa atgttgtcgc atctcctatt tttgtctctt
    30601 gatcaaaaaa ttcttatact tgatactcac actcattttg tatggattta gaaaagaata
    30661 tgtgtcttga cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca
    30721 tattaggaga gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta
    30781 ttgattggga tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct
    30841 tcctttactt tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt
    30901 gcagtggctg ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc
    30961 gcattgcgag cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag
    31021 catccgagta tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg
    31081 ttcaattttg tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt
    31141 tactttattg gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc
    31201 atcttgatgg ggattggtgg gctcatccac agtttagttg attataatat tgcttatttt
    31261 atagcaggaa cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa
    31321 aatcggaaag agtcggttca agggtacgcg aagaaaacga catattagac atgatctctc
    31381 aaaaaaaaac tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc
    31441 taaaaagagc tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt
    31501 ttgatgactt gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg
    31561 tcgactattt cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta
    31621 gaaccagttt ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct
    31681 gatttcacta cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct
    31741 ggacgaatac cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt
    31801 tttccttcag gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat
    31861 gtcacattaa agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg
    31921 ggtgtatcat aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata
    31981 acgattcggt cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt
    32041 gtttcaagac gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca
    32101 tctaaatttg ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt
    32161 cccaatgcca cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat
    32221 tctgtcagac ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca
    32281 tatttacgta atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat
    32341 gcgtagtttt ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact
    32401 tttccgccga tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa
    32461 gtagttgact ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt
    32521 gatagattaa aatcagttac agaataattt tctgcattgt catatttttt atatacgttt
    32581 ttcagagcca tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt
    32641 taaagtataa atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt
    32701 ttttttgtca atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat
    32761 acactggagt aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct
    32821 ttgatcgctc atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca
    32881 atattggaaa aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca
    32941 accggcttgc cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga
    33001 gccatgattt cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca
    33061 cagccccatg aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg
    33121 ttagctacga atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta
    33181 gattttcgaa gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc
    33241 gtatggaaaa ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga
    33301 taatatgcga tataatacga acgtattgga taatataaac aataatatta gtttttcgta
    33361 tttgcagtaa atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac
    33421 agagtagaaa ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga
    33481 cgtaatgttc gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa
    33541 ggagatgcta aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt
    33601 attgattgca ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa
    33661 aatcagtgtc acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc
    33721 agggataggc gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt
    33781 ctttattgga tttacattga atgcatttat tgaaggagca atctacggat tctttttcta
    33841 tcgaaaagag atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat
    33901 caacttattt ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg
    33961 ggtcgtttgg gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc
    34021 catttattac gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca
    34081 cgctaaataa aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg
    34141 tgaattgtgc ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg
    34201 tgcccatttc gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg
    34261 tggacaggcg atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt
    34321 gttggatttt tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca
    34381 tagggggatt actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata
    34441 tctttaaccc ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt
    34501 catacatata agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc
    34561 caaaacgaag attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc
    34621 caaaactttt acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa
    34681 ttgttccttt tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg
    34741 cccctgtttt tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt
    34801 cgatcaaacg ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt
    34861 tgatattttt gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat
    34921 cgatcaaatc aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc
    34981 cagaaagttc gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca
    35041 caccaacagt gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg
    35101 ataaataagc aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt
    35161 gtgcccgttg tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag
    35221 cttcttcttg ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc
    35281 ccgagatatc cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa
    35341 cgatccaact cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg
    35401 gacttagacg catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt
    35461 gattgaaggc cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga
    35521 cgatatttcc gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa
    35581 atgcatcttt tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga
    35641 tgagccattg actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga
    35701 acagtcgatt gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt
    35761 gtaacgtcat cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa
    35821 tgtcttttgc ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt
    35881 tttttacttt cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga
    35941 ttgagcaagt aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa
    36001 gatatgatgt gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc
    36061 aagataagtc tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa
    36121 agagtcatct aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg
    36181 ctgtttttgt ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt
    36241 tggaagctga cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt
    36301 ttctgtggcg tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac
    36361 agaagtttgg ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac
    36421 atccattccg tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg
    36481 tgtcaaagtc gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt
    36541 cagctgaaat gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac
    36601 atggtcaaaa gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc
    36661 aagaatcgaa ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg
    36721 tgtgaagatc acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata
    36781 attgatcaaa gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc
    36841 aactgtcagc aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag
    36901 ggcagagata ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa
    36961 cttctctgtt tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt
    37021 ctgactaacg tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac
    37081 ggtttttttg atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa
    37141 cagacctact tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg
    37201 tgctctgatc aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt
    37261 tgtcattcgg gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt
    37321 attgattttt ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga
    37381 agcatagtat tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca
    37441 taagcccatt tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga
    37501 agccatcatt aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc
    37561 caaaatgatt tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct
    37621 cctattattt atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa
    37681 tttagaatga aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt
    37741 agaaattgaa tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt
    37801 cattcatagg aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata
    37861 tatcaagtaa atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa
    37921 tcttttttgc tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca
    37981 aagaaggagt atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag
    38041 gaataaataa tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac
    38101 gaagacaacc tcccgacatc aagtcaaaag ctacttgaga ttttgatctg aaaataaaaa
    38161 aagaaaacaa ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa
    38221 ctaagagtgg tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct
    38281 gaaagcatca taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata
    38341 aggatttgta atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat
    38401 ggaaggattt atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta
    38461 tatattgcgt atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag
    38521 gcaaaaatac aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag
    38581 tatgtttcct gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt
    38641 tcatatgttg aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa
    38701 ttataaggga taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa
    38761 gattttattg acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga
    38821 agaaggaaat tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga
    38881 acgaggtctt tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca
    38941 gtcattattt gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag
    39001 tgatttattt ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt
    39061 atttttctat cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat
    39121 tctcttttat gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag
    39181 ctctttacta tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta
    39241 aaagttattt agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt
    39301 ctgcaccatt catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta
    39361 gcaatttgtt tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg
    39421 cttttgaagc agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag
    39481 aaggtcagga aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac
    39541 ctaatttgtc acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta
    39601 gtcatttctt aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta
    39661 atcagcgtag tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa
    39721 gaaaaatggg gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga
    39781 aattatccgg aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat
    39841 atgctgaaca gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac
    39901 tacttgcgca gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc
    39961 agaccttaga gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt
    40021 ttgagcaaat cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa
    40081 aattaaagca agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag
    40141 aaaaacacga gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg
    40201 aaactgccta tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct
    40261 atcagcgaag cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag
    40321 aattagaaca acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc
    40381 tggaattaag taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga
    40441 cgatctatct aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg
    40501 ctgctcacgg ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag
    40561 aggatctatt tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag
    40621 aaatccttga ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca
    40681 tgggatctct gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga
    40741 ttttgaataa tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg
    40801 tatcattaga agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc
    40861 tctatccaga ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta
    40921 cggcggtcca cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa
    40981 tcatcccata tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca
    41041 tatacgaagt cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc
    41101 tttcattaga agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca
    41161 ctactatgaa tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat
    41221 tggaaaaagt actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg
    41281 atcattttat gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat
    41341 tagcgttgta tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg
    41401 aaacctatca aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta
    41461 aatctgcgtt tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg
    41521 cctatatcta tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt
    41581 gaacataagc aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta
    41641 agtgaaaaga ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt
    41701 tgcttcaggg atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt
    41761 attcgattgc tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat
    41821 gaggtacaaa gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa
    41881 cgaattctta caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc
    41941 actattgatt gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca
    42001 gcaggtgcta actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa
    42061 aatagaagaa gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat
    42121 cggttattac acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt
    42181 ttgattgcta atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc
    42241 aagccacaag gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa
    42301 agcggggtga cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat
    42361 aagctggcag aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa
    42421 cctggtactc gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg
    42481 aaacgattaa ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa
    42541 gtggatgtaa gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt
    42601 attaggaatt gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc
    42661 tcgtccgatt gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat
    42721 cattatgggc gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat
    42781 tccacctgat gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc
    42841 cggtacagaa accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa
    42901 aaatatttac ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga
    42961 agaaggaaat tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt
    43021 gatgcttggt gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct
    43081 attaaatatg attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc
    43141 agctcttggt tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt
    43201 tttcttaggt tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt
    43261 tggtgcgatt ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca
    43321 aacaactgca ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa
    43381 cgaaaaaaga gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt
    43441 atgaacgtca gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat
    43501 atcagtcgaa agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga
    43561 ccccacatat cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg
    43621 atgatcctga atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc
    43681 ttgcagggtt aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg
    43741 gtacctcttt agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca
    43801 atattccgca cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg
    43861 gttttttgaa aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta
    43921 ttattggact gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt
    43981 taaaaatcgg ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc
    44041 caaatatctt atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga
    44101 aaccattaac gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga
    44161 ttttttaaaa aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag
    44221 gaagtactaa gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa
    44281 acagtgaatt tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag
    44341 ccagcattgg aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc
    44401 aattatggaa aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa
    44461 agtgcttcta ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct
    44521 atcacaaatg acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt
    44581 gccggggtag aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta
    44641 ctactcttag ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa
    44701 gactacatgc aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg
    44761 gaagaatttt ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt
    44821 ggatatggtc caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc
    44881 cgcgttccgt cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca
    44941 gatgcttcgc atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa
    45001 aagttgcaaa gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa
    45061 gcaagaaacg agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta
    45121 gcgcttgtcg ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac
    45181 ttgaacaaaa agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg
    45241 gaaatcatgc tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct
    45301 ttacgtccgc aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc
    45361 tattatctag gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat
    45421 gggaaaagca acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac
    45481 aaaagattaa caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa
    45541 gtagtgaaag cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat
    45601 aaagcgaaca gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga
    45661 acagaacaaa tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc
    45721 gaagcttatt cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa
    45781 gcagagaaaa aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt
    45841 atgcattatt ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt
    45901 tactgggaag aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac
    45961 gggacgttag agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa
    46021 cagagagtgt tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca
    46081 ttgatagaca caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt
    46141 ttgtctttct tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg
    46201 aactgccatc cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg
    46261 gataaaaaga atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa
    46321 atattggcat caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata
    46381 atctgtttaa tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag
    46441 ttgttgcatg gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg
    46501 ttttgtatcc agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa
    46561 tctgtccgtt gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta
    46621 aatcaatact cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt
    46681 gtcaaaactg cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag
    46741 actattgtaa catatcattg attatttcaa gta
//
LOCUS       DACGLI010000020        46219 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.021, whole genome shotgun sequence.
ACCESSION   DACGLI010000020 DACGLI010000000
VERSION     DACGLI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.021"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            160..840
                     /locus_tag="IXT22_001161"
     CDS             160..840
                     /locus_tag="IXT22_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4862541.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="IXT22_001162"
     CDS             930..1964
                     /locus_tag="IXT22_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4862542.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="IXT22_001163"
     CDS             1978..2313
                     /locus_tag="IXT22_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862543.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="IXT22_001164"
     CDS             2297..4777
                     /locus_tag="IXT22_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862544.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="IXT22_001165"
     CDS             4833..6392
                     /locus_tag="IXT22_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862545.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="IXT22_001166"
     CDS             6389..7753
                     /locus_tag="IXT22_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4862546.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="IXT22_001167"
     CDS             7924..8994
                     /locus_tag="IXT22_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862547.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="IXT22_001168"
     CDS             9009..9677
                     /locus_tag="IXT22_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862548.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="IXT22_001169"
     CDS             9697..10275
                     /locus_tag="IXT22_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4862549.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="IXT22_001170"
     CDS             10676..11587
                     /locus_tag="IXT22_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4862550.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="IXT22_001171"
     CDS             complement(11965..12882)
                     /locus_tag="IXT22_001171"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAQ4862551.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="IXT22_001172"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="IXT22_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAQ4862552.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="IXT22_001173"
     CDS             13579..14127
                     /locus_tag="IXT22_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAQ4862553.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="IXT22_001174"
     CDS             14242..16602
                     /locus_tag="IXT22_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4862554.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="IXT22_001175"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="IXT22_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAQ4862555.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="IXT22_001176"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="IXT22_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAQ4862556.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="IXT22_001177"
     CDS             19108..20007
                     /locus_tag="IXT22_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862557.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="IXT22_001178"
     CDS             20000..21262
                     /locus_tag="IXT22_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862558.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="IXT22_001179"
     CDS             21423..23321
                     /locus_tag="IXT22_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAQ4862559.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="IXT22_001180"
     CDS             complement(23651..24370)
                     /locus_tag="IXT22_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAQ4862560.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            24707..25039
                     /locus_tag="IXT22_001181"
     CDS             24707..25039
                     /locus_tag="IXT22_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862561.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="IXT22_001182"
     CDS             25026..27029
                     /locus_tag="IXT22_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAQ4862562.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="IXT22_001183"
     CDS             27048..27518
                     /locus_tag="IXT22_001183"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAQ4862563.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="IXT22_001184"
     CDS             27539..28123
                     /locus_tag="IXT22_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAQ4862564.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="IXT22_001185"
     CDS             28138..29124
                     /locus_tag="IXT22_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAQ4862565.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="IXT22_001186"
     CDS             29114..29425
                     /locus_tag="IXT22_001186"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAQ4862566.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="IXT22_001187"
     CDS             29447..31228
                     /locus_tag="IXT22_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAQ4862567.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="IXT22_001188"
     CDS             31221..32597
                     /locus_tag="IXT22_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAQ4862568.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="IXT22_001189"
     CDS             32604..33239
                     /locus_tag="IXT22_001189"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAQ4862569.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="IXT22_001190"
     CDS             33269..34624
                     /locus_tag="IXT22_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAQ4862570.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="IXT22_001191"
     CDS             complement(34816..36210)
                     /locus_tag="IXT22_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4862571.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="IXT22_001192"
     CDS             36302..37273
                     /locus_tag="IXT22_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAQ4862572.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="IXT22_001193"
     CDS             37270..38052
                     /locus_tag="IXT22_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAQ4862573.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="IXT22_001194"
     CDS             complement(38221..38592)
                     /locus_tag="IXT22_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4862574.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="IXT22_001195"
     CDS             38726..39169
                     /locus_tag="IXT22_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4862575.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="IXT22_001196"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="IXT22_001196"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAQ4862576.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="IXT22_001197"
     CDS             complement(40040..41407)
                     /locus_tag="IXT22_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4862577.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="IXT22_001198"
     CDS             complement(41391..42221)
                     /locus_tag="IXT22_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAQ4862578.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="IXT22_001199"
     CDS             42384..42821
                     /locus_tag="IXT22_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAQ4862579.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /locus_tag="IXT22_001200"
     CDS             42897..43517
                     /locus_tag="IXT22_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAQ4862580.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="IXT22_001201"
     CDS             43706..44212
                     /locus_tag="IXT22_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAQ4862581.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="IXT22_001202"
     CDS             44229..45128
                     /locus_tag="IXT22_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAQ4862582.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="IXT22_001203"
     CDS             45215..46099
                     /locus_tag="IXT22_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4862583.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15236 a         7977 c         9766 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DACGLI010000021        46111 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.022, whole genome shotgun sequence.
ACCESSION   DACGLI010000021 DACGLI010000000
VERSION     DACGLI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.022"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            414..947
                     /locus_tag="IXT22_001204"
     CDS             414..947
                     /locus_tag="IXT22_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAQ4862584.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(1437..1961)
                     /locus_tag="IXT22_001205"
     CDS             complement(1437..1961)
                     /locus_tag="IXT22_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862585.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="IXT22_001206"
     CDS             complement(1954..2427)
                     /gene="tsaE"
                     /locus_tag="IXT22_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAQ4862586.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(2550..3530)
                     /gene="pta"
                     /locus_tag="IXT22_001207"
     CDS             complement(2550..3530)
                     /gene="pta"
                     /locus_tag="IXT22_001207"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAQ4862587.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(3683..4363)
                     /locus_tag="IXT22_001208"
     CDS             complement(3683..4363)
                     /locus_tag="IXT22_001208"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4862588.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            4489..5358
                     /locus_tag="IXT22_001209"
     CDS             4489..5358
                     /locus_tag="IXT22_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4862589.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            5384..5899
                     /locus_tag="IXT22_001210"
     CDS             5384..5899
                     /locus_tag="IXT22_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862590.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(5946..6509)
                     /locus_tag="IXT22_001211"
     CDS             complement(5946..6509)
                     /locus_tag="IXT22_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862591.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(6564..6743)
                     /locus_tag="IXT22_001212"
     CDS             complement(6564..6743)
                     /locus_tag="IXT22_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862592.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(6820..7329)
                     /locus_tag="IXT22_001213"
     CDS             complement(6820..7329)
                     /locus_tag="IXT22_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862593.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(7425..7805)
                     /locus_tag="IXT22_001214"
     CDS             complement(7425..7805)
                     /locus_tag="IXT22_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4862594.1"
                     /translation="MNLTTIHPIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            8135..8884
                     /locus_tag="IXT22_001215"
     CDS             8135..8884
                     /locus_tag="IXT22_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAQ4862595.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKLTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(9068..10345)
                     /locus_tag="IXT22_001216"
     CDS             complement(9068..10345)
                     /locus_tag="IXT22_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862596.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="IXT22_001217"
     CDS             complement(10424..11068)
                     /gene="pcp"
                     /locus_tag="IXT22_001217"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4862597.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11267..12211)
                     /locus_tag="IXT22_001218"
     CDS             complement(11267..12211)
                     /locus_tag="IXT22_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4862598.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12213..12899)
                     /locus_tag="IXT22_001219"
     CDS             complement(12213..12899)
                     /locus_tag="IXT22_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4862599.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            13372..13692
                     /locus_tag="IXT22_001220"
     CDS             13372..13692
                     /locus_tag="IXT22_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4862600.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            13853..14758
                     /locus_tag="IXT22_001221"
     CDS             13853..14758
                     /locus_tag="IXT22_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862601.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            14755..15528
                     /locus_tag="IXT22_001222"
     CDS             14755..15528
                     /locus_tag="IXT22_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4862602.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15705..17129)
                     /locus_tag="IXT22_001223"
     CDS             complement(15705..17129)
                     /locus_tag="IXT22_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862603.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            17340..17786
                     /gene="nrdI"
                     /locus_tag="IXT22_001224"
     CDS             17340..17786
                     /gene="nrdI"
                     /locus_tag="IXT22_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4862604.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            complement(17856..19838)
                     /locus_tag="IXT22_001225"
     CDS             complement(17856..19838)
                     /locus_tag="IXT22_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4862605.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(19852..20748)
                     /gene="murQ"
                     /locus_tag="IXT22_001226"
     CDS             complement(19852..20748)
                     /gene="murQ"
                     /locus_tag="IXT22_001226"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4862606.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            complement(20751..21812)
                     /locus_tag="IXT22_001227"
     CDS             complement(20751..21812)
                     /locus_tag="IXT22_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4862607.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(22024..22551)
                     /locus_tag="IXT22_001228"
     CDS             complement(22024..22551)
                     /locus_tag="IXT22_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4862608.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            complement(22618..24120)
                     /gene="lsa"
                     /locus_tag="IXT22_001229"
     CDS             complement(22618..24120)
                     /gene="lsa"
                     /locus_tag="IXT22_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4862609.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            complement(24378..25499)
                     /locus_tag="IXT22_001230"
     CDS             complement(24378..25499)
                     /locus_tag="IXT22_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4862610.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            25625..26566
                     /locus_tag="IXT22_001231"
     CDS             25625..26566
                     /locus_tag="IXT22_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4862611.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(26709..27605)
                     /locus_tag="IXT22_001232"
     CDS             complement(26709..27605)
                     /locus_tag="IXT22_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4862612.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            27887..29227
                     /locus_tag="IXT22_001233"
     CDS             27887..29227
                     /locus_tag="IXT22_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862613.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            29422..29865
                     /locus_tag="IXT22_001234"
     CDS             29422..29865
                     /locus_tag="IXT22_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4862614.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(30127..31545)
                     /gene="nhaC"
                     /locus_tag="IXT22_001235"
     CDS             complement(30127..31545)
                     /gene="nhaC"
                     /locus_tag="IXT22_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4862615.1"
                     /translation="MEKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKKYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDILEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(31949..33172)
                     /locus_tag="IXT22_001236"
     CDS             complement(31949..33172)
                     /locus_tag="IXT22_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAQ4862616.1"
                     /translation="MTTTLSTNQLKDLIQYRLPEYQALALAIHDHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTGFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDEIGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDAALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAALSTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSEKGLASIAIAAELLANTALDLLREPKLLEKIKQE
                     HQEIVARKKQEGATF"
     gene            complement(33204..34043)
                     /locus_tag="IXT22_001237"
     CDS             complement(33204..34043)
                     /locus_tag="IXT22_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAQ4862617.1"
                     /translation="MKKIIRFAVITFVAIIWLAGCSQGKAATTEKKETTVKLGIIGED
                     TDVWDDVKDRLKKENIHLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNEEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENKKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDEHARPYVNIIVARKEDEDNKTYQKIVDAYQTEETAKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(34060..34740)
                     /locus_tag="IXT22_001238"
     CDS             complement(34060..34740)
                     /locus_tag="IXT22_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862618.1"
                     /translation="MTEFFKTYLPNVYLIPDEFIEATKQTLYMSFWTAFIGGIIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILVLVFLSQFISN
                     QLIKKVTH"
     gene            complement(34742..35815)
                     /locus_tag="IXT22_001239"
     CDS             complement(34742..35815)
                     /locus_tag="IXT22_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862619.1"
                     /translation="MIELRDISVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEAGK
                     IIEKGSSIQIFSHPEEELTKDFIRTATHLDQALETISAHAAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKVTILQKNELDNRIKVIEGGN"
     gene            complement(36465..37136)
                     /locus_tag="IXT22_001240"
     CDS             complement(36465..37136)
                     /locus_tag="IXT22_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4862620.1"
                     /translation="MKGAIFDLDGLLVDTERTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVQAAGSPEKVQEVRAKREEYFYQQLTSGAIQLKPYAKEILTDLKERHM
                     KLGIATTTVTKRATDILDHFQLADYFDTFTFGDEVSENKPSPVPYLTALERTGLEALS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYSVEEKEKLNLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(37214..39892)
                     /gene="mgtA"
                     /locus_tag="IXT22_001241"
     CDS             complement(37214..39892)
                     /gene="mgtA"
                     /locus_tag="IXT22_001241"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAQ4862621.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASPNGLS
                     EEQIERSRETYGENAISYGKKTPFIIEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGEYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNDTLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEAAETLDTDTINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVAPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELITGEKISEMNDHELAQVAEEHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKIPFIQSNATFAMLVITTLGIIVGSVLPFTGFGAELGLM
                     PLPGNYWLWLFITVVAYLALVTAVKKIYIRRFQELL"
     gene            40552..40989
                     /gene="ndk"
                     /locus_tag="IXT22_001242"
     CDS             40552..40989
                     /gene="ndk"
                     /locus_tag="IXT22_001242"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAQ4862622.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFATMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKGADAVPGTIR
                     GDYALPGTENIIHASDSRDAATKEIARFFPPFDTNKPSEKAAK"
     gene            complement(41011..41877)
                     /locus_tag="IXT22_001243"
     CDS             complement(41011..41877)
                     /locus_tag="IXT22_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862623.1"
                     /translation="MYDGELIKKLRVNKKLTQTQLAEGICSKTSLVGIETNSVKKVSF
                     GTLKSFLERMNMTLAEYEWIRNQLDEPKKLKKKRRMLDRIQEDSFDPYKEIANNRRHY
                     KKTEDLYYLVLNLHMSKKTEVSETEFEFLRYECRIIEEYLMQVPEYGQFEVSILADFP
                     WIFSDRFIENNYLKIKKRMRRIAQLNNHEQYLFTFLTNLTLFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKSENHQEFFAVIEYTLGKNQRNSL
                     EKKLLAIAKPSS"
     gene            complement(42111..44189)
                     /locus_tag="IXT22_001244"
     CDS             complement(42111..44189)
                     /locus_tag="IXT22_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4862624.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPATLGQTEGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTIL
                     YPVTGTNAEQ"
     gene            44682..45899
                     /locus_tag="IXT22_001245"
     CDS             44682..45899
                     /locus_tag="IXT22_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4862625.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETREKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEASPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT        13385 a         9686 c         8177 g        14863 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttaccaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca
     1261 aacggcaaaa tagttcctca tattttgccg ttttttgagc taataccgaa ggtcagctga
     1321 ttgaacaccg tttattcaaa aaaaatggac tgcgacacga cttttgtcac agtcccttcg
     1381 tgtgtttttc tgccttctca aaaggatgac agtttctcac tcttttccta tttcttctat
     1441 tcaatcaaat aactcatttt atatacatct aaaaattcac ctagatctgt tcttgcccct
     1501 ctaggcatga ccgcttcgat ttggaagccc atttttcggt aaaggtgtac ggctctttca
     1561 ttacgaactt gaacgtcaag ctccaatcga aaaagtacac ccatttcctt cgcccaactg
     1621 atgatttctt ctagcataag agtgcctagt cccattcccc aatattcctg cagaatactg
     1681 ataccgactt ctcccacgtg agacaaacga aattgactgt ctgccttgac agatgctgtt
     1741 ccaataatcg tcccttcata gattgcaagc agcaataaat tattattgct ttcgtatata
     1801 taatccaact cttcttctaa ggtttctggt ggtaacagga gttctgcttc atccaaaact
     1861 aaaaattctg tctccttatt aacttgtccc atcatcaaaa gaatgtcttt tgcatctcct
     1921 ggcactgctt cccgcaagat gatcccaact tcttcactca tgattttcag cccatttttc
     1981 tagaattcgc tgtttgaagg tttcactttg ctccccgtat gagattagtt tcacataccg
     2041 cttttctaaa tctgtatcac ttttttctaa aatcagttcc aaataatcct ccggcagtgc
     2101 ttcttctaat agatttcccc attcaacaac ggaaagccca tcaccttcaa aatattcatc
     2161 taaccctaaa tctgctccgc tagctgctac ccgataaata tccatatgat acaacggaat
     2221 ccgaccttga ctatattctc taataatcgt gtatgtcgga cttttgatca tttgcgttat
     2281 ccctaatcct tgggcaattc ctttcgtcaa cgttgtttta cccgcaccta gatcaccagt
     2341 caatatcaga ttgtcacctg gcattgcgga atgaccaatt gcctctgcga attgttctgt
     2401 cattgttaat cctgatagtt cgatcatttt tcatcttctc ccgctcttct ttctttttgc
     2461 cagtatatcg cgtaatgaag tttttttaaa gaaaaaatga actagtcaag aacagcagct
     2521 gctgtttttg gctagttcgc gtgtatttgt taatcaatca atgtttgtgc tgctgtgata
     2581 atcgataatt tatatacatc ttcttcattt gctccacgag acaaatcaga aaccggtttg
     2641 ttcaagcctt gtagaattgg tccgattgct tcaaagttac cgaaacgctg agcaatttta
     2701 tagccgatat ttcctgactg caattctgga aatacaaaga ctgttgcttg accagctact
     2761 tctgaatctg gcgctttcag ttgtgcaact gaaggaacat aagaagcatc aaattgcaat
     2821 tcgccgtcga tcatgtattg tggcgctagt tttttagcga ttttagttgc ttcaactact
     2881 ttgtctactt ctggcgattt cgctgagcct tttgtcgaga agctcatcat tgctactttt
     2941 ggttcgatat cgaacaattc tgctgttttt gcagaatcta cggcgatttc agccaattct
     3001 tgcgcagttg gattcacgtt gatcgcacaa tccgaaaaga catatttttc ttgatctctt
     3061 ccacgtacca tgatcatcgc tccgcttgtc cgactgatgc caggctttgt tttgatgatc
     3121 tgaagtgctg ggcgaacagt gtcgccagtc gaatggatcg ctccagagac cattccgtct
     3181 gcaatcccca tatacgtaag catcgtacca aagtaattca catcttttaa aatcttttct
     3241 gcttgttctt tggatgcctt tccatttcta cgttcaacaa aagtatccac catttcatcc
     3301 cacttatcgt aattatcagg gctgatgatc gtaaagctag atgttttgat tcctctggca
     3361 tgcgctgcat ttcttatttc ttcttcgttc cctactaaaa tgggttccac aagttcttct
     3421 gctttcaacc gggcagctgc gcctaaaata cgagcatcag tagcttccgg gaaaacgatt
     3481 ttgatcccac ggcgaacaat tttaaatctt aaactatcaa acaattccac aagatgacct
     3541 ccagacgttt ttatatgtat tatcatacac tattccagaa aaaaagaaca gtttatttta
     3601 tctgtatcag tcaaaaatgc tggaaaaatt aagtttttca catacaaagc gaactgcact
     3661 ataacaggaa agcgctgttt tattacactg tttcaggcag ttgccaatca atcggttctt
     3721 ctcctaacgc aaggagcgca tcattcgttt tcgagaaggg tttggaacca aaaaagccac
     3781 gacttgcaga taacggactg ggatgtggag atgttatgat gatatggcga ctcttatcga
     3841 tcattttgat tttttcttgt gccggttttc cccacaagat aaacacgatt ggtttttccc
     3901 gttcatttaa tttttcaatg atcgtgtctg ttaatctttc ccaacctttc ccgcgatgag
     3961 aatacgcttg cccttcccga acggtaagaa cggtgttgag taaaaggact ccctgtttag
     4021 cccatgacac tagatttcca tgttgaacag gtgcgattcc aagatcatca taaagctctt
     4081 tatagatatt tcttaacgat ggcgggatct ttacgccagg ttgcacagaa aaagataagc
     4141 catgagcttg attttctcca tgataaggat cttgtcctaa aatcaccact ttaacttctt
     4201 cataaggagt caattccaat gcttcataga tatgatacat atctggatgg atcttttggg
     4261 acgcatattc tttttttaaa aattctctta gatgcagata ataatctttt gaaaattctg
     4321 aggacaaaac ttcttgccaa ctgttatgaa tgatttcttt caaaaactcc acctcctaat
     4381 aaaaagaata actcacattt tcttcaatca caagggacaa tcttcaccct cagcacttga
     4441 ttaatatggt aaactaggaa caagaagcag aaaggaacga taatcattat gatcaaatta
     4501 attgcatcag atatggacgg cacattatta gatgcccata tgagtgtttc tcctgaaaat
     4561 gccgaggcga tacgttttgc aaatgatgcc ggtgttgagt tcatggtcgc tactggtcga
     4621 aactatcaag aagctcgcgc agctttagat gaggtaggaa tcgattgtgc gatgatcact
     4681 ttgaacgggg cacaggtatt tgataaagaa ggaaattcat tgtttaccgt gtcgattcca
     4741 aataatcaag caatctctgt tttagatatt ctagatgcta acggtattta ctatgaagta
     4801 gcaaccaacg atggtcttta ttctgaaaat caagcgaaac gaattgaaag ttttgcttcc
     4861 atggtggcta cccatttacc tcaccttacg tataaaatgg cgattgccat ggcctcagct
     4921 aagctggagt tattgcacat cacatacgtg gacagtattc gtgctatttt ggaagaaaag
     4981 aatctggaag ttttaaaaat tatttgtttt catacagaag ggccagctgt attaggtcca
     5041 gttggaaagc agatttctct tttaggcgat ctagccgtta cttcctctgg tcaaaacaat
     5101 atcgaagtga accataaaaa cgctcaaaaa ggaattgctg ttgcccatgt cgctcacgag
     5161 cgtgggattt ctttagaaga agtcatgacg attggcgata acttcaatga tgtcagcatg
     5221 ctgcaagtag caggagtcag tttcgcaatg ggaaatgcag aaatcgaagt aaaagattat
     5281 gccaaatata caacggacac aaaccttgaa tctggcgtag gaaaagccat attgcgcgcg
     5341 attgcagaag acttgtagtt ttatctagaa aagagggata tagatgtcag aatttttcat
     5401 tcaggaaaag cagcttggac gtgcaactcg gacaattgtc aaaaacgaaa aaggacattc
     5461 cctgtttttg atggttggtc gctggggaac aaagggcgat gcattgtctc tttatgccat
     5521 gaatggcgat ctcgttgctc acatcaagca gataagcctg acattcggta cgcgttttga
     5581 gctgtataaa gagttcgaaa aggtgggaac catgcagaaa atattcaatt ggcccggtga
     5641 cttttattat attcgtagac ttcactggac agtccaaggt gatatctata atcatcaata
     5701 tcaaatccat catttcaatc agcaaatcat gaaaatggat aaagcaacac ttttttcagg
     5761 agattactat gtattggatg tctcaaatga tgaagatgct ccagtttgta tttgtattgc
     5821 tgcggtttta gattactggc tctaccgtaa agacaaaagt cgcgataagc ctgtttctta
     5881 ccgacttaac ttaagttaaa aagatgtacc tgaaatgcgg aaatacgcat ttcaggtaca
     5941 tctttttaga tattcttttg catatgatca taaagatgac cactgatcat ccgctgaccg
     6001 acaactttga agtcatggcg ttcgtataat tttttagcct ttggattttt ttcatccaca
     6061 cttagaccga tgacggagcg attagctttc ttcgccaatt taggtaatgc ttctaataat
     6121 cgcgaaccga tgccttgtcc tctaaaatct tctgatacac tgatagagtc caaataccat
     6181 tcgttgggaa acgtttcttt atcaatgaac aaacgtgtag acgcatctag ctgatatttc
     6241 tctaagatag gtaccagtgg ctgatcgatg attgattctt cttcatctgt ataaccgtaa
     6301 gcaactcctg caactttacc gtctatttct tctacgatac ctcgtgaata actgtaacga
     6361 taatttggat cagtgattgc ttcttctaaa atctctaaag tcttttgttc ccctgtctgc
     6421 ttcaaaaatg gcagttccat atcttttaga atcactaaga tcaatggggc gatttctgga
     6481 gcatcttctt ttctcgcaaa acgaatcata gtttcctctc cttttctcca ttctaacatg
     6541 cagaaaaaga aatcgcaaaa tcgttatttt aaaaaatctt caatcttttc agtaatgaaa
     6601 taaccatgag taacgattct tgccgcttca gttcggcaat aagggcagac gactggcatt
     6661 tctttatcat tatgttcgac tacattattg acttcttcgt atgcaaattt ttttccgcaa
     6721 ttagggcatt tcattttttc catgttatct caacttcctt tcatctttac tctcttagct
     6781 tactcttata ttgtaaaaaa gagaagcaat atccttcttc tatgcagata tccatacctg
     6841 acggtcctgt tctccatcta ttaatcggac tttataataa ggacgttcat ctttgactag
     6901 aagtgtccac tctttcactt ttgctttttt cccgtagtag ctgactgctt ccttcatcgc
     6961 tgcttgcggt tgtttgaact cttccgtttt ttctatatca aaaagatgtt ctgcggcctt
     7021 ttccgtgtca tttcgtacgg ttgttttccc agtggatgga ttgactgcta tgacttgtcc
     7081 ttcacaaaaa aactggtatt catatgttgc attcgtagga ttctccaaat ctttttcaac
     7141 tgcaaaatga atagcagata tgttatgttc ttttgtttcg ttttttacga ttgctgctgc
     7201 ttttttcaat gagatccgat attcctggtc actaatatca tccatgtgaa aagcggcatt
     7261 gagcagtccc gtcataccgg taatccctat tacgatgagg gcagcaacac caaacatcat
     7321 ttttttcatt cttcattctc ctgtttcttt tttttaaaga atatcaagaa atgaacgaat
     7381 gaaaaatcga atgaaacgaa aaaaaagtga caattttgtt atctttattc gtgcagttct
     7441 aatggcaatc cgtctggatc aaagaaaaac gtcatttttt ttcctgtaaa ggtatcttct
     7501 ctaatcggtt ctgattcgat ccctaaggac tgcaattctg caattgtttc ttcaatatcg
     7561 tctactttga aagcaagatg acgcaagcca caagcttctg gatagtttgg tcgttgtggc
     7621 gcattagcaa ttccaaaaat ctccaattca gcacttccta gtttcagatc taatttatag
     7681 tcatctcgtt ctttgcggta attttctctg attacttcaa atcctaattt attaacataa
     7741 aaatcacgtg atttctgata atctgaaaca atgatggcta taggatggat cgttgtaagg
     7801 ttcatatgag cactcctatt cttcgtttaa gctcggatct atattaatct ccagttccat
     7861 tgtaaatgtg tcagattgaa aaaaatagct gtttttcctt tttataagaa aaaaggcaaa
     7921 aaaaacagaa agtaggtcct ccaagacact cttcctgttc ccaatataat aaatgaaagt
     7981 aagaaattat attttcaaga aaacaaacag aaaattatca taacacaaat tatttataat
     8041 tgaaagacta gttttttttc aagaaaagca tacaatagat tgtgttagta aatacagaac
     8101 acactacatt tagtgtctta aggagtcctc atacatgaag tcatattttc agtttttagc
     8161 tcatcagcta aaaggctggc cgcaacaaaa ttattatctt ttctttttca gtcttggctg
     8221 ccaggtcatg actcttgtca atagtcccat cacttggctg tccgttatta catttatcgg
     8281 taccacgctt ggtgtattgt gtattttatc catcaatgcg gcaaaatcag tcaacggtat
     8341 tttaggtatt ttgtctgcga tttgttttat tatcgttggg ttttcagcaa agaactattt
     8401 aagtatcggt gaacagattg cttatatgat cacattggat atccccgtat tgttaagtaa
     8461 agaatggaat cataatatgg cttcaaaaat ccgaaaatta actggaaaaa gctggtttat
     8521 cgcaatcatc agtactttcc ttgtctatct tgtttcagga ttcctgattg gtcgttatac
     8581 agatgatcct cggccgtggg tagatgccat tgctttttct attagcttga ctgctggtat
     8641 catcagtttc ttgcgttaca acaaccaata ttactggtgg ttagcttcag ggcttgctca
     8701 aatggtcctt tggtatattt catttacgca tggatctgca agtttggcga tgttcgtgaa
     8761 cagctctgtt tacttgctga atgatgtcct tgcatttacc gtttcacctt ggtataacca
     8821 aaaagaacgt gaacgtatgc aaaaaatgga agaagaatac tacaacgcac aacaacacgc
     8881 ataaaaaaac tgagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
     8941 tataaacggc ggaatcagaa gcaactcctt cggaaataag ctgaaattca caaaaatttg
     9001 aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
     9061 ctatttttta tagtaattcc ttcagatact ttcttgcctc atcattgaaa cgcagtgatt
     9121 cttctaactt ctgataatat tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt
     9181 ttcctttcca tttgtcgatt gtctcttgca catttccaga ttggatatct ttcactacta
     9241 gttgccattt ttcttttgag actgtacggt ctttcttatc agcagattgt atagcttctc
     9301 gttctttacg caatactttt aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga
     9361 acccttctgt aaaaccatag cgacaatatt gcttccaaat aaatagatag atttttggtt
     9421 ggatgaatcg ttggtttttc gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt
     9481 gacgttttgt ctttctcaac acggaaataa atgtttcaaa ataagcatta ggatgtactg
     9541 gcacttcttc atatacgatg gattgccaat ctttacgtaa aaatgcgcga tagttgatca
     9601 agaattcttc tacatccttt actaattctt ctgcaaagtc gtcaaatagt tcttttttta
     9661 tctgtcgctt ttttgactgc ccattgatgt gttcacttat tttcttgatt tcattttcca
     9721 atgcttgata atccgctatg taaatcggca tttctacttg gcgaaattct gcgagccgct
     9781 gagctaattt tatatccggt aaatatggct gtttcatccg acgattttgg tacaagacaa
     9841 aacagtattt ttgccatagt ccttcaggaa aatcgatatt cttctgctta agccataata
     9901 attcgtctaa ggccagatca acttttgtca ttccctgatg gatcgaagct gccactgtcg
     9961 gagagacatg caggtgatcg gcaaagtggt tgatgcctag ttttaggatc tttccggttt
    10021 ttggcgattt aacgatgtat tgcactttta attctctacc acactcacaa tacaattttt
    10081 gctggcttcg ttttgttcga aaaaacggat tgatcttgaa gtcagaaaac acccaatctg
    10141 ttgcagctaa ataatgttct tccataaaac gagagctgat tagatatcgg cggtgcttat
    10201 cgactagttc ccgctgtttt ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg
    10261 tgtattgttt agaaattttg atgggatagc ttttgctgat ttcttttgga aaccattctt
    10321 caaagacgga ttgccattct tccacggctg tttctttcct ttctaattac aaaaagctgg
    10381 ctactaacat aacgttagca accagccagt gtttcttgct aaattagtga gttgttccgg
    10441 catttccgga aatatcttct ttattttcta ctgctgcttc aactgcataa gtcaaagaag
    10501 aagcaatgtc ttctaaagac atagaaggcg tacccactgg acgatcgatc acttgatcgg
    10561 gtgagaatgg cacgtggatg aacccacctc gaattgccgg gaattgtgtt tcgatcaaat
    10621 gaagcaaacg atacatgata tcattgcaga caaatgttcc tgctgtataa gagatgtacg
    10681 ctggtagacc atgatcttgt acattttttg tcattgcttt gattggcaat gaggtaaagt
    10741 aagcggctgg accgttttct tctaaagccg tatcgaatgg ctgatttcct tcattatcag
    10801 ggattcttgc ttctgctaga ttgattgcga cacgttcgaa cgagactgct gaccgcccac
    10861 ctgcttgtcc gacacagatc acgacatctg gttggtgctg ttggatggct tctttgacta
    10921 cttgactgct tttttcgaat acggtcggta cttccacttt gatgatttca gcaccgctga
    10981 tttcatctgg catttttttt actgcttcat aggctggatt cactttgtcc ccaccaaatg
    11041 gatcaaaacc tgttactagt actttcatct gttgttcctc cgtccgattg atttaacata
    11101 tggttatctt ttatcatacc attttccttg aacagcgtaa ataaaggaaa caatagttta
    11161 aataacataa cagatcaaac ttaatatatt cttataaaaa aatagtgttc cactacaatg
    11221 ttagaagagg ttgcgacaat tattctgtca caacccctct cttctattat ttaaatagaa
    11281 tcatataagc aatttggaaa actagcataa ataacgcaat aaacaactgg tttttgatca
    11341 ctccgtattt gtctttcatc tccagcatcg ctacaggcac gatattgaag ttagcagcca
    11401 tcggtgtcag cagggtccca caaaaaccgc aagtcaatgc aaccattcct attaacgctg
    11461 gattcgctcc atgactaaat acgaatggtg caccgatccc aaccgtcatc acggtgatgg
    11521 ccgcaaatgc attccccatg attaccgtaa atatcaccat gccaagagcg taaatgatga
    11581 tgccgatgtt cacatttcct tctggaacga tcgtacctac tgcattggaa atcactgtcc
    11641 caactccagc gcttgtaaat accgcaccta gagaagctaa aagcattggc aacatgctta
    11701 acggccctac tgtgcccagc atatctgctg catcatctaa aaatgtactt ggtcgattat
    11761 ctcgagaaaa gaacatcaag attagcatgg ctgcaaaaac accgacgccc acgccgacta
    11821 aagcacctaa attggtaaat agagcaaaca agatcgcaaa gacaccgata ctcaaagctg
    11881 gaataaaaat tttcattcct agtttgtctg acattttttc catatattct tttgatggaa
    11941 gccggctttc tcctttgctg actttcttag caattgctgg tatggtcatc gcaaagatca
    12001 agccaccgtt cacgattgcc ggaagccatc ttcctcctgc aataactacc cctaagaccg
    12061 tccagaaaaa ggctgaccca taacgatgag gattggtttt atctgttaaa tttcttactc
    12121 cagtgtaaat caatacgagt cccatcacga tataaaggat ctccagtaat ttatcgccta
    12181 ataaaatatc aggatttgta aaaaagtcca tcttattgcc cctttcctgg ataatatttc
    12241 ttcgctaatt tcttttcttt aagatagaag tagacacttg ccacaactaa agccgtgata
    12301 gccactggaa cttccactaa agcaagctgt cccaatgtta cgtcatatcc tagatctttc
    12361 agtgttgatt ggactagcaa cgcccctgct cctccgatga atagtacttg gccaaagaac
    12421 cagcagacat tttccatagc tgaagccata ccttttagtt cttcttcatg cttaggatgg
    12481 acttctaacc cttttgattc gatggtcccc aatgccatcg gtaaaatgat tggacgaaca
    12541 aatccagcaa ctccaccaaa actcacgtta aaagccgcaa agatcattcg aaagatccca
    12601 taaatatcta caatcatacc agcagatact ttcttgaatc gcttgatcaa ggaagccgct
    12661 gattctttca gaccatttct ttcaagcgtt cctgttgcca acataatgat gataaaaatc
    12721 gccatcccgc gattgtttac aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca
    12781 agaccgccag tcaaagctgt aacaactaaa gcaaccatta cgatcaatat cgagtctaat
    12841 ttaaatgcaa acccgagaat aacaatcaag acgcctaaaa ggctaagata attttccata
    12901 tattttcctc cataaaatga caatattttt ttaattataa agcaaaacac ataaaaaata
    12961 tagttgtttt ctcacgaaat agacactatt tttaaatatt tttcgttatt tttttattat
    13021 ataattcacc ttacttattg taagataaag ctttttttaa tttattgcct gctaatatat
    13081 aaaaataagg tctagttact gtttttttaa atgattaata aataacaact cctttctatg
    13141 aaattgcaaa gcattcatct tcttttctgc taacgatata tccgtcaatg cttgttacac
    13201 tttactaaaa agtatgagat tgccgatatc tggataggtg tgctatacta cagaaaaaga
    13261 tatacgatct gccaccgggt agtaaaaaag aggatgatca ttccattagg tctttgaagg
    13321 gatgattctc ctctttttgt gtatttttta tattgaagga ggaacgtatg tatggcatgg
    13381 atggaattaa tcatagcagg aattttggaa gtattctggt caacgatgat gaaatggagt
    13441 gatggttttt ctaaaatcaa ttattctttt tacacagtga ttggaatgat tgctagtttt
    13501 tactttttgt caaaggcaat caaaagtttg cctatgagtc tctcttatcc tatttggaca
    13561 gggattggcg cagttggttc ggtcattatt ggtgtggtct tgtttcatga taagctgaat
    13621 ctttccactt ggttctttgt cgggttgctg ctcatcagca tcattggcat caaaatcact
    13681 agcggtcact agatacttag acaagcagac aaggactgat cagaaaaagc ggggcttttt
    13741 atttgatatt cctctttcta tgaaaaaaca agaaaataag actaatgacc tagcgacttc
    13801 tctactcatc aggtgtatgc ttgtactatc tatagaaaag gagtgaatat ttttgaaaag
    13861 tctttcggtc caagaattat ccaagaactt tggtcacaaa caagccctca gcgatgtcag
    13921 ttttagctta tctcctggca aaatcgttgg attagtaggt cctaatggcg ctggaaaaac
    13981 aacgatcatg aaagctattt taggactgat ccattactca gaaggaacga tccgtattgg
    14041 tgaaaatgag atttctccct ctagtcataa aggattagaa caagtaggag cattgatcga
    14101 atatccgggt atctatccat tcttaacagg ttatgatcat ctgaagttat tctctgaaac
    14161 aaacgatgta tctgctatcg acactatcgt gaaacagctc aagatggaaa aatacattca
    14221 caaaaaagcg aaatcctact cgctgggaat gaaacaaaaa ttgggaattg ctcttgcctt
    14281 actgaaccat ccgtctatcg ttattttaga tgagccgatg aacggtttgg atccacaagc
    14341 aacaagagat gtgcgaaaaa tcattaccga cttggctact cagggcacct ctttcttgat
    14401 ctccagtcac ttactcagcg agcttgaaaa aatggtcgat gagctgatcc tgatcaatca
    14461 aggaaaaatc atcaaacaat gtacaatggc tgaattgaac caaacagcgc aagatttcat
    14521 cgttatctct acgacaaatg atcaagctgc tcgaacgatc ttgacagacg ctggatatcc
    14581 cttggaagat cctgataaaa tcaagcttct aaaaaaaaac gaagagttat taggaactgt
    14641 tatccagtta ttgtctgcag aaaatgtcca tgtgacagat gtccagcatc tgacgaatga
    14701 tttggaatct tccctattgg aaattctgga ttcagtaaag ggggaagaag aaaaatgacg
    14761 ttgcttataa aacaagaatt atttaaattg atcaagaaaa agtcaactgc tgttttatct
    14821 gttctattag ttgctttgct cataggaaca gcacttctag ccaaaaaata cacgacgatc
    14881 attgatccag ttgaaatgac tgctcagctt ttcagtgcca catcttggat tgtctttatc
    14941 atgattgctg ctgcaagtac gatcatttca atggaatcac aatatggtac attgaaaaat
    15001 ctcctttatc gaaagtattc tcgaggagaa atattagtaa gtaaatggat cacattagtt
    15061 atttattcta tttatttata ccttttagct attattgtca ccgtgctgat gaaactgatc
    15121 cttttccctt cgatttcctt tacggagaag atttctactg gtcagacact gatccaaagc
    15181 ttattcactt atactttggg tagttatatc ggtttatggc taattttaag tttagtgttg
    15241 atgattgctt gttttatcaa tagttccggt gcctccatct cagcagggat cgtcttttat
    15301 tttgcttcat caatcatatc tggtatcctc atcgcactca ttcaaaaatg ggagtggatc
    15361 aaatggaatc caatcagtat gctgaatctg caaaaccaaa ttggcaacga agagattatg
    15421 aagcaattga ctcatctttc tactaatcaa atgctgtttg gcaatttagc ttacattgct
    15481 ttgttcttag cattgggata cctcgtattc aagcgaaaaa atgtatgatg gttcattaac
    15541 aaagaagttg tgacagaagt ggccagtttc aagaaatttc ggcttatttt tagaagaagc
    15601 tacttcttga acaccattta ttcaaaaaaa gaagcgatga cacgaatgtt gtcaccgctt
    15661 cttttttgaa taaaccacag gcttcacagc ctctctttat acttctatac gtgaagcatc
    15721 ccagtggcaa ataaaaccat tgcgattact ccgaccatcg tcacaccgat aagtaaaatc
    15781 ttatctaagt ggatatgttg tacaggttcg ttttgttctt tacgtgcttt gaggtaaaaa
    15841 taaatacctg gtaagaaaag aacaagaaca agcatcactt cattaaaggc tacaactagc
    15901 atggcccata cttgaaaagc acttgctaaa aaccctacta aaaattggac ccactctttc
    15961 cgctgataag aaagcttcat ttggtacagc cctaagaaaa gccacgtgaa gaaaatcgct
    16021 gctgtaccaa gtgtataagc aaagttatat gcactgtcag tgaataataa tgaaagtaaa
    16081 aagacattcg tacataacgt cgtcaatacg atagcataag ttggtgcccc atttttgttg
    16141 agttttcccc atgctttagg caaaagtccg tcctcagcca tattccccat tgtttcaatc
    16201 ggcaagattg tccatgagag ccaaacccca actaaagaaa tgatcaaacc gccgttgatc
    16261 acgaccgccc cccatttacc aaccatcatt tcaaatacat atcccatagc aggttgcgct
    16321 ttgatcgttt gcagctgatt catcgtcatt gtgccatatg gaagcatgga aaccaagacg
    16381 taaataatga tcaaaccgaa tattcctaga atcgttgctt tcccaacatc cgattgtttt
    16441 tttgctcgtg aacctacgac agaagctcct tcaataccaa cgaataccca gagcatcacc
    16501 atgatgcaac tcaatacttg actagaaaac gggatcggct gcccattcgc attcaatatg
    16561 atatcgctag aaaagttatt aatgaattgt tggatcgaaa aggtgctgat agctactaca
    16621 ataaataaaa ataatggcac taatttacaa aatgtgacga tagcattgac aaagctagca
    16681 ttttcaactc cacgattcac tagccatgca tatccccata agaagatcgt actcatcacg
    16741 atcgatgcca cattttgacc accttcgaat acggggaaga aataacctaa tgcactcatc
    16801 aacaatgttg cgaacgccac gtttcctaac cagcatgtga gccagtaacc ccaaccgctg
    16861 ataaaaccag cgaaacggcc aaaaccttct tctgcgtaac taaagatccc gccttttaaa
    16921 tctggacgtt ttttattgat attattgatc gataaggaga gcatcaacat tgctgttcct
    16981 acgagtaccc agctgaagat agctgggcca ccagccgatc cggagatgtc cgtcataata
    17041 ccaaatacgc cacctccaat cgctgaacca atcactaagg cagcaagtgg aatcaaacca
    17101 attccttttt tctgttgctc tgtatccatg taagcatcct ccaaagtaaa accgctttta
    17161 tcaaaaagta taacaaacct tttttatttt tacttaatta ataaaaactt taatagaaat
    17221 ataattctac cgactttttt ctcattatac aagcaaagcg cctagtccct ttccaaatta
    17281 caccaccaaa aaaacttaaa aagatgctat actaaaggga aagaattggg ggatgatcca
    17341 tgaacatttt atatatatcg atttcaggaa atacgcgtgc ttttgccaaa catctagcag
    17401 aatatgctga aaaaatgcat gcagaagatc ctgtcaatcc tgaagttact ttaaaagaaa
    17461 tccatgaaaa tagtgatttt acgaaagaaa cagaaccatt ttttactttc gttcctactt
    17521 atttagacgg cgggaatggg ttagacaacg gtgacacaga aatcttgacc gaaacgatgc
    17581 gcgaatatct ggaatacgaa gacaatcata aactttgcct tggtgtagtc ggtagcggta
    17641 ataaaaactt caacaatcaa tattgtctga cagccaaaca atacgcacaa agattcggct
    17701 ttcctttctt ggcagattat gaattacggg gaacaccatc tgatgtgaca cgcgtttatc
    17761 aaattttggc agaaaaaaat aaataacaca aaagaagaag ctgaaaaata aatttcggct
    17821 tcttcttttt atgttctcta ttgtttctat tcttattaag ctttgacatc catcacaggt
    17881 gcttttgctt tcgctttacc tgttttttcc aagacaaagt tttttacacg atccatattg
    17941 gttaccaaga cgatcatgga ggtttctttg tctgctgctt tgattgcttc taagtcagct
    18001 tctgctacaa gcgtatcagg tgtcacttgc tgtccttctg ttactttcac atcgaatggc
    18061 gtaccgccta agtcaactgt gttgatgccc atgtgaagca agatttctaa gccatttggt
    18121 gtcgtaatgc cgatagcatg ttttgttggg aaaacagaac ttattactcc agtaaccggg
    18181 gaatagatat gtccgttttc tggttctaca aagtaacctt cacccatcat tttttgtgca
    18241 aaaactgggt cacttgcttt atctaaagaa acaactgttc cgtcagcaac tgatgataag
    18301 atagtcacac tttcagctga agcttgaggt actgcttttt caggtacttc atttactgtg
    18361 gctgtttcgg tcgctagttc ttctttttct aaacggtctt taggaatacc gaagaagaat
    18421 gtagcaacga agccaccagc gtaagcagcc aataaaccaa ggatatagcc taaccattta
    18481 ccatcagaga tcaatggaat caaagcggct cctgaaggtc caatagcgat tgctccgaca
    18541 tttccgatca ttccgatcac tgccccaccg atacctccac cgatacaagc agtaataaat
    18601 ggacgtccta gaggtaatgt tactccgtaa atcaatggtt cgccgattcc taagattccg
    18661 actggtaaag cccctttgat catttctgtt aattctttgt cttttttgca gcggatccat
    18721 aatgccaatg ctgcacccac ttgtcctgct ccggccatcg caaggattgg aagcaataag
    18781 gtacgaccag tttcatcaat catttgtaca tggattggcg tcaagatctg atgtagtccg
    18841 aacatgacca ttggcaagaa taatgtacct agaacgaagc cggcaaatgc tcctccaaca
    18901 ccaagtaccc agttgatccc accgaccatg ccgtcagaaa tgaaccctgc taaaggcatg
    18961 atgaagaaaa tttcgatcag accgatggca atcagggaaa gagttggcgt aacgatgata
    19021 tctaccgcat caggtactac tttatgcagt tttttctcaa cgattgacaa taaccaaact
    19081 gcgaagataa cacctaagat cccgccttgt ccagttgcaa gagcttcacc ggtaaacaag
    19141 tttttcagtg gtgcttctgg attcatccct gtcagcatca caacagcccc gataactcca
    19201 ccaagcgttg gcgttgcacc aaaaacttgt gcagcattga tacctgtata gataactaga
    19261 tagctaaaca tcccgttttt caagatgttc atcacatcga tatattgttg ccatgttcct
    19321 gcgtctagtg ttccagctgt gactaagttt gctaaaactg cggcaatccc tgccacgatc
    19381 ccagtgccga caaatgcagg gatcattggt acaaagatat tagagatgtc ttttaatacc
    19441 gatttgattt tagagggttt ttgtttcgat ttttgtgccg ctttcatttc ttgtgcccgt
    19501 tcgtttacac ggtcttttcc agatgcagaa gaacttgctg tagttgcact agcagaagga
    19561 agtttttctc ctaatttcac gcctgctaag tcaaccattt cctgcgctac tttgttcact
    19621 ttcccaggtc cgatgatgac ttggagctgt tcatcctcta ctacgccaag tactcctgga
    19681 atcgctttta attccgagac atttacaaga tcatcattga tgaccttcat acgtacacga
    19741 gtcatgcagt ggacaatgct ttcaacattg cccataccgc ctgctccttg ataaatttgt
    19801 tttgccagtt cttccaaagt caattcgttt tttgccatgg tcttttcccc ctcataaggt
    19861 tccttttaca aaaccgtttg cttcagctaa ttttgcttga gctgcctctt tatcactatt
    19921 tgtcaaaatc atgacgatag ccagtttgac attttgatct gcttcctcaa agtacttttc
    19981 agctgtttcg tagtcagctt ctgtcgcttg catgatgatt cgttttgagc gttcaattag
    20041 tttttcattt gttggtttga cgtcgaccat caagttattg aatactttac cgataccgat
    20101 catactgata gtagaaatca tattcaaaat cagtttttgt gctgttcctg acttcaatcg
    20161 agtagagcct gtcaaaaatt ctggtcctgc atcgacttcg attgggaaat ccgcatgctc
    20221 gctgatttct gcttgtttat tgcaagaaat cgttcctgta acagcaccaa tcgattttgc
    20281 gtaatctaat ccaccaatca catatggtgt acgaccgcta gctgcgatac caataactat
    20341 atcatttttt gttaaattca gcttgattag atcttcttgc cctaattcat aagaatcttc
    20401 ggctccttcg acggctacag tcattgcttc ttctccacca gcaattaggc ctatgaccat
    20461 ttccggttct acaccgaatg tcggtacaca ttcagcagca tctaatacac caagtctacc
    20521 actcgttcca gctcccatat aaatcaagcg accacctttt ttaaaggatt caatcgtgtt
    20581 ggcgatcact ggctcgatac ttggcagttc tttttcaaca gcagcggcca ctttctgatc
    20641 ttctttgttc atgagttgga ctgcttgaga aatactcatt tcatctaatc caaaagtttc
    20701 ttggtttctg cgttccgttg ttaggttctc taaattgatt ttgctcattt ttatcttcct
    20761 tcttttctta taaattgata gttcatacca gctttgattt ggttgatcag cggtagttct
    20821 tctttgatga ctttggctac tacattcact ttttcatccg ctggcaaatc atatttagtt
    20881 aattggatct cacccatata gcgcaaatac ttttcgttat ctaaagtaat agatcctttc
    20941 atacgcttag ctgtatttct tactgggatt ggcggaatct ctcgaaaacg cgcatctgcg
    21001 cttcgtatga catctcttgc atcatcttgc cgattcgtat gttttcctaa tatatattcg
    21061 taaaaaactt catctacagg ttccgtatgg agcaagactg tctgttcttt ttggaaagaa
    21121 gcaaattgct cctgaacgtg ttctgacaga cctgcatctc cgatataaac aatatccgtg
    21181 ttacttgcta atagatcaag agcacctgcc agaggatgga tccctcgatg ttcttccaaa
    21241 gttggtaatc cttgatacag tggacctctc aactctgtat ctcctggtac aaagccttgt
    21301 acaaggaatc cttgagtttt gagccattga tttttttcct gataccattc tttgtccaac
    21361 cctgtttcaa gacgtggata ataattatgc caagcttcaa tctgtgagaa atcagccgct
    21421 gcttctttca actcatcgat atcattaggc gtgatcgtgc tggcattcaa actgattttc
    21481 aattgatgtg accagtcggc gatctgctga ttagaaatat gataatccat tcttaaccct
    21541 gttacaccaa ttgctttcaa gggtgttaga tcttctaatg aaaagccagc tcgtttcaat
    21601 gcctctcctg aaatatcgac catcaactct agtttattct ttttcgcttc gcttcctagt
    21661 tcgatcaatc gattttgata agccgaaaca tcatcttccg gtatatgcat ggaagtgaaa
    21721 ataccgacaa agccattgga tgccatttgg cggatatact gtttcttctc ttctgacaaa
    21781 gaatcattca taaatattga aaagccaaac atattatccc tctttttctg tatccgtctt
    21841 catttctatg actagagtat atatctaaag aaacaaaatt tcaatacttt tgttaaaata
    21901 attaaatttt atttctaaaa attggattta taatgccaaa agaattgaca cagccacaaa
    21961 aaaggcactg ctaagcaaaa gcagtgcctt gaaacatttt atttaaataa cacaaaagtc
    22021 taattactca taagaaatta attctgtatt gtctaccatg aatgtaaaga acccttcatt
    22081 aggcattgga tgaaaataag cattgatcac tcttatcaag gcattatgac agactaacaa
    22141 gtagacattt tcttcgtctt ccatgcattc tttcaataaa ggaacgatcc gtgcgtacac
    22201 atctaagacc gactctccat ttgggaaacg tacagcaaac gctaaacgcg ctttttgaaa
    22261 gttttcatct ttgcttggca gtccgtcata atccccaaaa tccatttcta ccaatcgctc
    22321 atcagcggtc atcggcaaat tgagacgatc aactactgct tgtgctgtat ctcttgctcg
    22381 ttgaagaggg gaatggatga ttttcgtgat tggaacaggc aaatctacta ccttttctgc
    22441 tagtgcctgt gcctgcatct gtcctttttc agtcagcggc acatctgctc gcccgcaaac
    22501 taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt acataaagca tgtgattctc
    22561 tccttcgttg acaaagttct ccttaaccat accttgttgt ctttgagatt acaaggttta
    22621 gattttctca agagaaataa tctcagtaga tactttatct agaaaggttt gatcatgttc
    22681 cactagtaac atagcaggtt tcacgttcaa aatcagttgt tctaattgtt cttgattgaa
    22741 gacatccaaa taattcaatg gttcatccca tatatagagc tcagctggtt gggataaaga
    22801 tttagccaat tccacttttt tccgttgtcc catactcatc tgttcgattt tattatgaaa
    22861 aacatctctt tccatcccaa gctttcggag attattcaaa aatgcttgat agtctactcg
    22921 gtttttcttc gcgaattccg ccaatgtccc tcgattgtct tcataatttt ggcgtacgta
    22981 actaatggtc aaatgtttgg gctgggattt ttctcctaca accttgccgt tgaatgtccc
    23041 cagaagataa tggataatgg atgactttcc cgcgccgtta ggacctgaaa ttgccatccg
    23101 ctgatgaggt tcgatcgtaa aatgaactgg ctcgaataac agattttcat accctaattg
    23161 aagattttct acgcttaaca gccgtttatg atgagacact tggctattca tcgtcaaagc
    23221 atcgatatac tcgatatctt ttaataattt ttctttctca ctgatctggg tttccatccg
    23281 attcacgatt gctttagatc gtttcatcgt ccgtgcagca tcagcgccta ctgctccttt
    23341 attcactcgc ctagattccg tatcgatgaa tccgactttt ttctttgttt tgtccccttc
    23401 tcgggaacga gaccattctg ctttttcagc tgctgttttc tttagcctgc tgacttcttt
    23461 tttcaatttt tcatttttag ctatttcaaa ttcatcacga agttttttct gttcttcata
    23521 gatagagaaa ttcccttgat aaagttccag ttggctcttt tcgattgcta aaacatggtc
    23581 cactacttca tcgataaatc cccgatcatg actcaccacg atgaatcctt gttttttctt
    23641 tttcaagtaa gccgctactt gttttctgcc agagatatcc aaatgattcg ttggttcatc
    23701 gattaacggg aaatgagtgt catccacaaa taagagtgcc agtaggactt ttgtcttctc
    23761 tcctcctgat agtgtgctga attctctcca taagatttca ggatctgttt gcatcagttg
    23821 gagctctctt tcaatttccc atatctcaaa atccataatc tcatttaaca cataataggt
    23881 caaacgctct ttatcttttg tttgctgcgg gaaatagaca aacgcttgct gatggatcac
    23941 ttgcccttga taagggagtt tgttttgcag gatattcagt aaagttgtct ttcctcgacc
    24001 gtttcgtccg ataagtccta gtttccattg tgtgtcaaag tttagattgg cttgttcaaa
    24061 taataatgtg ccttggctgt catagccgaa tgtcagattt tttatttcga ttttagacat
    24121 tattccatca cctcgtaaaa aaagaccagt cctattttca gaactggcta aagaggatgc
    24181 aagggttggg gcacacaaaa agacccatac atcgaaagaa ccaagccaat cccgaaaatc
    24241 tgcacactgc tcccttgtct ccacaaggta cagtctgaat gcagctttca tcaatcgact
    24301 taatttttca atgcacggat ccctcacttt gtcctatatt tgaaattacg atagcataaa
    24361 gaaattgttt ttgtcaacta cttcgggaga atgttgaaaa atctgctgag tgtctgtcct
    24421 aagatttctg ttttttctaa tgtttgcctg tgttccattg cttcctctaa atcgattggt
    24481 cctaattgaa tgcttaagac aatggggaga aaatcaaaga gtccttccag ctctcggtct
    24541 ctacttccgc aaatagcgat tattggtttt cgatattttt ttgcaagcac tgctacgcca
    24601 tatggaactt ttccgtggat tgtttgctga tcaatccgcc cttctcctgt aatgatgaca
    24661 tccgcttgtt cgatctgttt ttctaatcca gtgatttggc tgaccaactc aaaaccagag
    24721 accatcttcg ctcctaacaa aaaaagggct ccgccaatac cgcctgctgc tccgcttcct
    24781 gggatgtcat ctaaatccac ctcccaaaca tcttttatct gctgagcaat cttttcagct
    24841 tgtttatcca agaaagctaa cgtcgtatcc gttcctcctt tttgtcttcc aaattgccaa
    24901 gcagctcctt gttgacctgt atatgggttg gtcacgtctg cagcgatgat cacttttact
    24961 ttagaaacaa gaacgttcct tcgatccaaa tgaagttttc tagtagataa caaaggattt
    25021 ccttctgtgt acccttctaa agaagcaccc aaagattgga gtaatcctag accaccatcg
    25081 ctacatccgc ttcctcctaa agtgacaatg atttgttcca cttcttgaag cagtgtatct
    25141 ttgataagct ctcccaaggc ataactagaa gcaagtcgga tggtttgatc cgttggttta
    25201 tcaagtaaat ctaatcctaa tacttgtgca gattcaatga ctgcggtatt ttttccttgc
    25261 cagttcgtca ataaataact gatttttcgc tgacgaaata agagatccat cccatcaatc
    25321 gtacgccagg ttcccccgag cgcgtaatag attgcttctg cagtattttc tccgccatct
    25381 gcaatcggca cattgatttt tcttccttta cggtcttccc aaccatttag aactgcctga
    25441 tttaattcaa atgaagaagc acttccttta aatgaatcga ttgccgccaa aatatccatc
    25501 tatatccctc actttcttct taagtaagac actttttttc acttttttca aacaaaacaa
    25561 tgctattttc ttctgttttt ctatatacta aaagggaact cattgaataa aggagagaaa
    25621 aaacatgaaa atcgcaatag ctggagccgg agcaatgggc agccgaatcg gattaatgtt
    25681 gcatcaaagc ggaaatgagg tcgtcttgat cgatcgctgg cctgctcaca ttgaagccat
    25741 tcgtacaaat ggattgattg ctgactttaa tggcaaagaa gtagttgcaa aactgccaat
    25801 ctattcacca gaagaaatca tcgaaagcaa caaacacgtg gatttgatcg tagccttgac
    25861 aaaagcgaat caattagatg atatgtttcg ttcgatccaa tccattatta ctgagaatac
    25921 ttatgttttg tgtttactga atggattagg tcatgaagat gtactggaaa aatatgtacc
    25981 aaagaaaaat atcttatttg ggatcacgat gtggacagct ggtctagctg gtcccggaaa
    26041 agtcacatta ttaggtgatg gagaaatcga actagagaac ttggaaccag aaggcgaagc
    26101 atttacaaaa aaagttgtag aagtctttca agaagcaaaa ttgaatccaa tctatagtca
    26161 taatgttcgt tattccattt ggcgaaaagc ttgtgtaaac ggaacattaa atggattatg
    26221 cacgatattg gattgtaata ttgctgaatt aggtgcgcaa aaagcggcag agggcatggt
    26281 tcgaacgatt gtatctgagt ttgcttctat cgcagcaaaa gaaggaatca cattagatca
    26341 agaagaagtg taccaacata ttgcttctac ttatgatcct gacaacatcg ggttgcatta
    26401 cccatctatg taccaagacc tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa
    26461 tggtgccgtt tggcgaaaag gacaaaaata tgatattgct acaccatatt gtgccttttt
    26521 gacccaatta gtccatgcaa aagaaggaat ccttggcgca gaataaaagg ctctctgatg
    26581 agaatcagct ggatcagcag ctggttctca tttttttacc cccatgaaag ttcaaaaaga
    26641 aaaacacaat tctcatgttg ccataagaat tgcgcttgtt tattttcatc tatgattggt
    26701 tggcactttt atttattttt aacagaggaa agatcgtatt catattgttc ataaatagcg
    26761 gagtcagtag tgaaaaaacg ttttgcccaa ttttctgcat caaaaaattc caacagttct
    26821 gatgggattg gttgaaatgg cgtatgcaaa aattccggta attcatctaa atcacgttct
    26881 tgaagcaaaa aaatattttc agaatgataa aactgataat gagctatggc ttgattatct
    26941 gtcactagtt tcttttgaaa atacatagat tcaaacgttc gcaaagtcac tccttgctgc
    27001 ccttcccgca acagttctag aatccccctc gattccccgg tttttttcag atattcttca
    27061 taagtaaggt atccaggttg ttcatttcct cgaagcggaa gaataaagta attggtcgta
    27121 acacctcttt ttgtaaattc ctgcttatat ttttctgccc gttcttttct gccgttattt
    27181 gttgcaccaa aaaatagatc cgtctttggt tcgctagaag aaaaatccat atgtttcgaa
    27241 taaaaggaac tattatgttt tagtccaagt tctttcgctt ctaaaaaatc aaaatgataa
    27301 atctcatcga ttgccggttc atcttgtgcc tgcttcagca tcgcctcgtg ttctgcttta
    27361 aagtggttcc aaaaaaataa cacgattttt gcattggtaa atggacgcac gcgtcgagcc
    27421 atctccatat caaatccata atctaaaaaa acgatcagct gataatttgc caactgttgt
    27481 cgagctgatt taatgaattc cgactgtagt aaatcttttc cggaccaaac atctaaagag
    27541 cggatggaag gaaaaaaata aagtgattta tttttcgcaa ttagcaatac gtcgtttttg
    27601 ttcatctgtt ccgcctcact ttctctgtca ctttttccta tgatagcctg tttaaatagt
    27661 aaaaagccag taaaacgctt cctattattt ttataaaaat ttaacatttc tatgaaaata
    27721 cgatgaaata aatcattctt ccattaaaat atgcccaaaa gttttctgaa tagttgtaat
    27781 tatctgaaaa tttgttatca ttagtcatta ttattattac tatttattct tactatttat
    27841 tcttactatg cattttgatt gtgaatttaa aagaaagagg ttatttatgg aagataaaaa
    27901 attgaaaaaa caacttagct cccgacatat caccatgcta gctttaggtg gagcgattgg
    27961 tgcaggtcta tttaaaggaa gtggcgaagc gattggaatc gccggccctt ctgtattgat
    28021 cgcttttttg attggcggca taattttata tatcgtgatg aaaggtctgg gaaaaattgt
    28081 tttaagtggt ggtgatacgc accacggatt atctggattg attcgtccat atctaggtgc
    28141 tcatgctgcc gattttaccg attgggtcta ctggtccatg tggattatca atatcattgc
    28201 tgaagctgtt gcagctgctt cctttttaca gttgtggttc ccccacatcc cagcttgggt
    28261 atttgttttt atgttggctg ttttaactac tatcatcaat ctttattcgg tacgattatt
    28321 cgcagagaca gaatattggc tggcctttgc taaaatcagt gtcattatcc tattgatcat
    28381 ttttgctgct tatcttgtcg gtcagcaaat gttgggtact ggtgttttcc ctacccttca
    28441 acaattaact gatcatggtg gttttactcc ccacggtatg aagggaatca tcagttcttt
    28501 gcttgtagtt atctattctt acggcggttc tgagttgatt gctatcacag taagcgaagc
    28561 agatgatcct aaacgtgcga ttcctaaagc aatcaaaggc gtcatgggaa gaatcatttc
    28621 cttttacatt attcctttat ttttgctttt gattattttt ccttggaata ctttagcagg
    28681 cacgaacgtt agtccttttg tgatggtatt tgaaaaaatg aatattccat ttgcggcaga
    28741 tatcgtcaat ttcgtgattg ttcttgctct gttctcgtct atcaattcag gtgtatatgc
    28801 ttcttcgaga attttgttct tccgcttgaa agatcggaaa ggttcctcta gaaaactagc
    28861 tgttttaaac aagcatcaag taccgcaacg tgctgtgctg ttttgtacca gtgttcttta
    28921 tctaggtgtg gctctttctt attttgtcgg tgacaaatta tttggctatc tggcaggttc
    28981 tctttcctat acagtattat tgatctggat cattatcagt gctgcgtcct ttgtactgac
    29041 actaaggaaa ggaacgttat gggacaaagg aatcagcttt tttgcattag cagtcttatg
    29101 gttgattttc cttggtatcc tattcacgaa ctccattggg gtaactgtat tgaccggttt
    29161 gctttacctg ttcatttatt tcagttatca aaaaaagaat gatgctttcg tcttgacgaa
    29221 tgaatgaaac caatagagaa ttttattcta tttatattga atatctggag ctattgaaaa
    29281 aaaggagctg cgacaaaaat tgttgcagtt cttttttccg aataaacggt gttcaaaaac
    29341 catctgtgca gattaattga ttgttctcca cgctcatgac atgatagaag aaaggaatga
    29401 agaaaaagga gtttgtttta aatgaaaaag tattggaagt ttttgttgat gattggtgtt
    29461 tcgacggtag tcatgtttgg tatgatgtat ttgaatgttt atgcgcttga tcatatcttc
    29521 ttcagtcgca cacgtgtatt catggcgttg atgatgggtg cagtcatggc agtcatcatg
    29581 ttgttgttca tgtggaaaat gtatgaaaac aaaaagataa atgctatgat tttagccgct
    29641 agtcttcttg tttttgccgg ttccttattt atggtacgaa gccaaacaac tgtcaacgat
    29701 acggcgtgga tgaaggcgat gatccctcat cactctattg ctatcttgac aagtaaacga
    29761 gctgatttaa aagatcctga agtaaaaaaa ttagcggaag aaatcattca ggcacaagaa
    29821 gaagaaatcg acaaaatgaa aaaaatgatc aaagaaatgg aatgaccatt atccatccaa
    29881 ataaaaaaag aggatgttcc agaagtgatc aacttcaaga aataagaaga agctacttct
    29941 ggaacaccgt gaatcagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
    30001 aaacaaaaat agcttctcat atttttcgtt tggttaggct tattaccgca aatgcaagct
    30061 tttgaacacc gtttattcgt aaaagggagt gtgacaaaag tcttgtcaca ctcccttttt
    30121 acgtttttat tgttctaatt gcgctgtctt gcttactgct tcttgcggtt tcacaaattt
    30181 ctttgagatc ccccaacctg taaaggcact gaccatcgaa aacacaggtg aaagcaaact
    30241 gaaaaacacg aatggcaagt aagtgagtgt aggaatgcca aatgtacttg ctacgaaact
    30301 tccggcgatt ccccaaggca ctaagtagtt gattactgtt ccaccatctt ctagtgttct
    30361 ccctaataca gttggatcaa atcctgcttt ttcgtaagtt tctttaaatg cattaccagg
    30421 caggataaca gatagaaatt gttctccaat aaagatattt actccgatgc ttgtcatcaa
    30481 tgttgtaaaa atcaattttg gggtgttcgt catctttctt gatactcgtt ccataacggt
    30541 tgagatcaac ccaaattcga tcaacaaacc acctaatgac aatgttagaa taatcaatga
    30601 cacagttggc atcatgcttt cgattcctcc acggctaagt agtgaatcga tttgttggtt
    30661 tccagtattt gaaacaaatc ccgattcgat gacccctgcc aacttcgtta aggaagtttg
    30721 tgggttttga ataaagatca ttcctactgc tacagcaata ttcaacaaaa tcgtcaaaat
    30781 tgccggtacc tttttccatg cacacaagag cattaaaaat agaggaatca gtgaccagat
    30841 cgaaatagta aagtttgctt ctaaaatatc agtcacttca cgaatagatg aaagacttgc
    30901 ggctttactt gtgtgtccta aaatcatgaa taaaaagaaa gaaacaacaa atgccggaac
    30961 agttgaccac atcatatgct tgatgtgttt gaacaaatcg gcatcaacaa tagctgctgc
    31021 taaatttgtt gattcggata atggagacat cttgtctcca aaaacggcac ctgaaacaat
    31081 ggctccaaca acaagggctg gatttagtcc tagtgttgtc ccaataccga aaaatgcaat
    31141 cccaatcgtt gacataacag taaaggcact ccctacagcg ctacctacga ttgcacaaac
    31201 aacaaataca gaagggacga accactggac actaatcaat ttaaatccaa tgaccatgag
    31261 ggttggaata attcctgctt gtatccatac agcaatcaat gaaccgacta aaataaaaat
    31321 aaagattgga atgatccccg gtttgatgcc attgatgatc ccttcgtgca gccaatctgt
    31381 cgggtatttt tttatcactg cgtacaacat gaccattccg atagctgcca aaatcgtgat
    31441 attaggtgaa acctttaatc cgacaacgcc aatcgcaatg cctaaaacaa tgaccatcaa
    31501 tacaagtgtt gcttctaaaa aacttggtgt tccttttttt tccatgataa tctctccttt
    31561 tttagttgtt cttatgttct aaaaaagtta agatatcgga ttactccgcc acaattcatc
    31621 cgcgattcct cctttataaa aataaaaaga cctgctttca actaaggacg aatgactccg
    31681 cggtaccacc ttaattaaaa acagatctgt ttttcacttt caaacgatta ttcaaatgta
    31741 tggactttcc atgtaattcg tcaattaggc ttgatcggtt cacagcgacc accgactttc
    31801 tgaacaaaac acctaaccac tactgcgtga aaagttgact tgtatgaagt ttaccttcca
    31861 taagatcatt tgtcaatgaa aaagaaaata ttttttcatt tttctgaaaa ttatttttat
    31921 aactttcgcg cacaacttta tctttttact agaaagtagc gccctcttgt ttttttcttg
    31981 ctactatttc ttgatgttct tgtttgattt tttctaatag cttgggttct ctcaataaat
    32041 ctagagctgt attggcaagt aattccgctg caatcgcaat agaagcaagt cctttttcac
    32101 ttttagcagc agctttgaat tcttctgtat gtccggcaat atatgtctca gagattgcta
    32161 cagtaggctg tatcgttgga ataacttggc taacatttcc tacatcagaa gaacctagac
    32221 ttgttctttg ttccgtttct atttcttcat caggaacccc tgcttctttt gcatgttgga
    32281 agaataagtc atcgaaagaa ggcgttacga tgacatcatc gactgcattt tggaacaatc
    32341 caaactcaaa agtcgtaccc gtgcttaatg cagcacctcg tacgatattt tccacttttt
    32401 catatacttt gtctaatgtt tgtcgatttc ctgcacgtaa atagaaacgt ccagcagcgt
    32461 agtctggtat gacattggcc gccacgcctc catctgtaat gattccatgg atattgacat
    32521 cttttggcaa ttgcaagcgt agagcgttga ttccgttaaa cacttggatc aaggcttcca
    32581 aagcatttac tcctttttca ggtgctgctg ctgcatgaga agcgacaccg taaaatttga
    32641 tatcgactgg atcatttgct aaagattctg tcgttttccc ataacgaaaa gctggatgga
    32701 cacataatgc tgcatcgaca tcctcaaaaa aaccttcccg aacgaagctt cccttagctg
    32761 atccattttc gcctccttct tcccccggag taccatacac acgaatttct ccgccaatct
    32821 catcaatgaa ttgtttcact atgctggctg ctaatacgga gtaagtacca aataaattat
    32881 gtccgcatgc atgaccaata cctggtaaag catcaaattc tgccaaaaag gcaattgtcg
    32941 gacctggttt attggaaata taacgtgcat caaagcctgt tcggtgccca gctacttctt
    33001 tttctaccca gaacccttct ttttccaatt gtttgattaa agctgctgag gaataaaatt
    33061 cataattact tacttcagga tggtcgtgga tagctagtgc aagtgcttga tattctggta
    33121 aacggtattg aatcagatcc ttcaattgat ttgttgagag tgtggttgtc ataaaaattt
    33181 cctcctatgc tagtcgtttt ttcttatttt ctcccgaatg tttcccacgc aggtacgctt
    33241 gaaccttttg atgttttttc gattactttg gctgtttctt ctgtttgata ggcatctact
    33301 attttttgat acgttttatt gtcttcatct tcttttcttg caacgatgat attgacataa
    33361 ggacgtgcat gctcatcgac tggttctaag aagattgcat cagaagcggg attaaatcca
    33421 gcatctacag ctacaccgct attgatgact gaaatatcta catctgacaa agcacgtgct
    33481 gtttgggaag catctaactc agaaatgtct agattttttt tattctcggt aatatcagaa
    33541 acggtaggcg cttggccttt tgccttgtcc actttgatca atccagcagt ttgcaataac
    33601 agaagagctc tgccgccatt cgtgacatca ttagggattg caacttttgc tccatctttg
    33661 atatcagcca catcttttaa cgtattggaa taaattccca acggtgcatt aaccgtattc
    33721 ccaatcgata ctaaatcagt tccgtgttct tcattgtaat tgtctaaaaa gaattgatgt
    33781 tggaaggaat tcaaatcgat cgatccatct gctaaagccg catttggctg attgtaatct
    33841 gtaaatttca catattccaa atggatgttt tcctttttca aacggtcttt cacatcgtcc
    33901 catacatctg tatcttcccc aatgatccct agttttacgg tcgtttcttt tttttcagtt
    33961 gtagctgctt ttccttggct gcatcctgcc aaccaaataa ttgctacaaa tgtaatgact
    34021 gcaaaacgaa taattttttt cattttttct cctccatttt caatgtgtga cttttttaat
    34081 cagttgatta ctgataaatt gactcaaaaa aactaagacc agaatcaata atgtagcgac
    34141 aatcgttaca tctgtttgga atcgattata tcctctcgat atagcaagat tccctaatcc
    34201 tccggcacct actgctccag ccatggtagt cagtccgatc acattgatga tcgtcaacgc
    34261 tgagacccga atgataccag gtaacccttc taacaaataa acacgtaaaa tgatgccgat
    34321 tgggctcgtg cccatcgctt ctgctgcttc gatcacccca ggatcaactt ctagcagtgc
    34381 attctcgatt tgacgggcaa aaaacgggac aacgccaaaa atcaaaggga ctaaagctgc
    34441 tttggcacca atcgtcgttc caactaagaa acgagtagtc aaagctaaaa gagaaagcaa
    34501 gataatgaaa gggatggaac gaatgatatt gatcaactta tcaagtattt cgaacagcag
    34561 cctgttagct agtaatccat ttggacgtgt cactactaac gtcacaccta agatgattcc
    34621 gatgatccca ccaatgaatg ccgtccaaaa agacatatat agtgtttgct ttgtcgcttc
    34681 gatgaattca tccggaatca aatagacatt cggcaaatat gttttaaaaa attcagtcat
    34741 tttagtttcc tccttcgatg actttgatac ggttatctaa ttcatttttt tgtaaaatag
    34801 ttacttttac accagattta atcaaataat ccaatgcttt ttgccgctgt ttggtttctc
    34861 cagctaaagt aacgatcaaa cttcctaagg gtgtttcttg taatagctct acattaccgt
    34921 ataagatatt cgctgttact tggtacttgc tgtaaagatg agcgattaga ggttcgttcg
    34981 tctggttgcc gatataactt aattccacca accatttatt tgcaatctga tcggcaaaag
    35041 cagcatgggc actgattgtt tccaatgctt ggtcaaggtg tgtcgctgtc cgaataaaat
    35101 ctttagtcaa ttcttcttca ggatgactga aaatctggat gctgctacct ttttcaatga
    35161 ttttccccgc ttccataacc gctaccttgt tgcagatttc tttgacaact tgcatctcat
    35221 gagtgatcag gacgattgtt agacctagct gacgatttag tttttttaac agtgcaagga
    35281 tctgaagggt cgttttcgga tcaagtgcac tagttgcttc atcgcataac aacactttag
    35341 gttcatttgc cagagctcgt gcgattgcca ctcgttgttt ttgccccccc gacagttgtt
    35401 taggatacgc agatgctttt tcttccagac cgacaagttc cagtagttca ttcacttttt
    35461 gacgacgttc ctgttttgat tttccagaat actttagaga aaaatctacg ttgtcaaaaa
    35521 tcgttcgact ttccattaga ttgaaatgct gaaagatcat accgatggcc tttctttctt
    35581 ttcgcaattc ttttggagag agctggctta aattcgtctg attgacgatg acttctcctg
    35641 ctgttggttt ctgcaacaaa ttcatcacgc ggactaacgt actctttcct gcacctgagt
    35701 aaccgacgat cccataaaca tccccttttt caatcgttaa atctacagaa tctactgcct
    35761 gtatctcttt ttctttttgt ttgaaacata cagaaatatc tcgcaattca atcattaaca
    35821 ttcctccttg tctataaaaa aagcatcctc aagaaaatga aaatagtcat tttcttgagg
    35881 acgccttttt gcgtgttacc acctcatgtt caagctgtgt tcacacacaa ctcctcttca
    35941 agtaccatca tactctagca agatatcggt cgcagccgtc accgccttac atctatgctc
    36001 gggatgaatt gctcgatggc cattttccaa tagtcgttcc ttgcttcttc tcagctaccg
    36061 aagctctctg tcaaaggttc ttctatcgta cttaccattt caatgcaaat aatattcaaa
    36121 aaaaaaatcc ttttactaac ataaactatg tcagtaaaag gacgacgtat cgtggtacca
    36181 ccttttttcg gaagtttcct tccctcaagc ccaacatctc aaaaagagag attggcgttc
    36241 gttttaacgg tcgaacattt ccgaatttgc ctacttatcg acaaattatt ctccaaggcc
    36301 attttcagct tttcttactt gactcttcac accagccaga gcctctctgc aaagtttcca
    36361 agcttacttt ccttctcaac gaaatcaata ttttgttgtt gggaataatc tacaggagga
    36421 aaactgaaaa gtcaagcatg aaatccaaat tattttttct atatttattt ttctgttttt
    36481 ttatctaaca tttcaataac agttcgaaga tcttttcctt ccgcaagaag gttcaatttt
    36541 tccttctctt cgacgctata atttcgaaca aaactggaat cgggaatcaa aacaacgcct
    36601 agtcctgcac gtgaagcggc tgtcgctcct actaaagaat cttccactgc aaaagctgaa
    36661 agagcttcta atcctgttcg ttccaaagct gtcagataag ggactggtga aggcttgttc
    36721 tccgatactt catctccgaa cgtaaacgta tcaaagtaat cggctaattg aaagtgatcc
    36781 aagatatctg ttgctctttt cgtaacagtt gtcgtagcaa tccctagttt catatgacgt
    36841 tcttttaagt ctgtcaatat ttcttttgca tagggtttca attggatagc tccacttgtc
    36901 agctgttgat aaaaatattc ttcacgcttt gctcggactt cctgcacttt ttcaggactg
    36961 cctgctgcct gcactaaaat atcaaaactt tgtttccagt tttttccgcc ccaagcgtca
    37021 acgatttctt tcgggatatg aatatcaaat tgctggaatc cccaaagcca accatcccga
    37081 tacgttcttt ccgtatccac taacaaacca tctaaatcaa atattgcacc tttcatctat
    37141 attccaaaac aatacaccta gtttagcatg actgatccaa aatgaacaga agcatagagc
    37201 ccagccgcat cacttataag agttcttgga atcgacggat atagattttc ttcacagctg
    37261 tcacaagcgc cagataagcg acgactgtta taaacaacca taaccagtaa ttgccaggga
    37321 gcggcatcaa gcctaactca gcaccaaatc ctgtgaatgg aaggactgaa ccgacaatga
    37381 ttcctaatgt agtgataacc agcatggcaa atgttgcatt gctttggata aatggtattt
    37441 tcggtgtacg caatgcatgg agtactaatg tttgtgtcca cagggattcg acaaaccatc
    37501 ctgcatggaa taatgcgata aaaatcactt gttgtgagct atccaatgta tggaaacttc
    37561 caccaactac agcaggacaa ataacaaaat acatcaacaa gtaagtagtg atatcaaaaa
    37621 tcgaacttgt tggaccaaaa taaaccatga attttccaat actagatgca ttccatttct
    37681 ttggctcatc caaatattct ttatccatcc gatcccatgg taaggaaatg caagaaacgt
    37741 catagatcag attcaaaaat agaagttgca aaggcaacat tggtaaaaat ggtaagaacg
    37801 tactggcaat cagtacggaa aacatattgc caaaattaga acttgctgtt gccttgatat
    37861 atttcatgat gtttccaaaa gtttctcttc cagaaagaag gcctctttcc aaaatcgtca
    37921 aatctttttc taaaaggatc acgtctgctg attcttttgc gatatccaca gctgtatcca
    37981 cggaaatacc gatatcagcc actttcattg ctggagcatc attgatacca tctcctaaaa
    38041 atccgacagt atgcccattt ttacgtaaag ctgtcgtcaa tcgtgctttt tgctgaggat
    38101 tcaattttac gaatacttcg tgttcttcag ctacttgcgc taattcatga tcattcattt
    38161 ccgagatttt ctcaccagta atcaattcat tgatttctag gcctacttga cggcacacag
    38221 accgtgtgac taattcattg tccccagtca gaacttttac agctacacca tgttctttta
    38281 aagctttcaa cgcttgtttt gttgtttctt ttggtggatc aaggaaagca agataaccaa
    38341 tcagaaccat gtctgactca tctttgactg aaaattctcc aacaacgctt ggattggtct
    38401 tttgtgcgac accaatcact cgtaagccgt cttcattaag tgattgtact tttgcaagca
    38461 ccgcttcttt tcgttctttt gttaatggtg cgacagtacc accaagatca ataaatttag
    38521 aaatgttcaa catttcttca atcgcgcctt ttgtgatcat ctgtgttttg ccagccggat
    38581 cagcgactac aacactcata cggcgacgtt caaaatcaaa aggaatttca tctacttttt
    38641 gataattgat tgtatctgta tctaaagttt ctgctgcttc atcaatgata gccacatcta
    38701 acaaattttt cagccctgtt tgatagtagc tgtttagata agcatggcgc aaaacacgat
    38761 catcttcatt tccttcacaa tccatatgat attcaagaat gattttgtct tgtgtcaatg
    38821 ttcccgtttt atccgtacat aacacatcga tcgcaccaaa attctggata gcatttaaat
    38881 ttttgatgac tgttcctttt ttggccatca cacttgctcc tttgaccaaa ttcgtcgtaa
    38941 cgatcattgg aagcatttca ggcgttaaac caactgccac agataatcca aaaagaaaag
    39001 cttctaacca atctcctttt gtaagcccat tgataacgat aactgctgga gccatcaatg
    39061 acataaattt gatcagcagc atggatgttt tgtggatgcc taattcaaaa cttgattgga
    39121 tgggtttttc agatagcgtt tctgctacat gcccaaatag tgtgtcattt ccgacagaaa
    39181 caatgattcc ttccgcgctt ccactgatga cattgcttcc cataaagaca agattttcat
    39241 aacttgtttc actttgctga tcgtcttcac atactttcgc atgcttttct actggatagc
    39301 tttcccctgt caatgctgct tgagaaatga atagatcctt tgcggacaat aaacgcatat
    39361 ccgctggtat catatctcct gctgaaagcc gaacaagatc tccacagacg atttcttcca
    39421 taggaatctc tgtatactcg ccatttcgtt tgacagctgc cgttactttc acaagtgatt
    39481 tcagtttttc agctgcttga ttagaacgca cagactggat caacgtcatc gtcccactga
    39541 cgataaccat agtgaagata atggctacac caaagagatc tttatctcct ggagcggcta
    39601 atacgtattc cgtaatgaat gaaataattc ctaatgcaat caacactaat gtaaagggtg
    39661 tgatgtatgc tttcaatatt tctataatga atggtgtttt tttgccatat gaaatcgcat
    39721 tttcaccata agtttctctt gaacgctcga tttgttcttc tgacaatcca tttggtgatg
    39781 catggaacaa ttcaaataat tcttgcttcg tttttccagc aaaagctgca tagatttttt
    39841 gtgtatcttt ctttttttcc atctcgatct ctcctttgtg tccaaaagac agctgttctc
    39901 gctgtttttg gtcttttgct attcatcgga tcgatagaga aaatgctgaa aggggctgag
    39961 aacagataga taatagccct ggcctttcct ctaaatcctt gtttttcgaa tgactgtcat
    40021 ccatttgttc tcatctcctt tactaagtaa ttttaattca tgacttccaa tcatttttcg
    40081 aatagttatt ttcccaactc gctcacctcc ctttttgttt tttcacctat gggatttgcg
    40141 gcaacaaaaa aacctctcgc caaatactca gcgaaaggtt tgaaaaagca aatcaaaaaa
    40201 agcttctcag atctcatcgt tgagttttga cactgtacaa cgtaaaaagc agatatctgc
    40261 ttttagctac cttatgaaaa gccttatctc gacaattcct gttctaccca ttggcgtctc
    40321 tcgacgtttt tgggcagtag cctatgtttg tataggagcc tcacctaaca aatcctattc
    40381 ggttttccct cgttaatata acaactaaaa aagaggatgt caaatcaatt ttccatgttt
    40441 ttcatacttt tttaaaatac acgcgttata tttcctgtct cacgcagttt tatttgtctc
    40501 attttccacc tcccgctata atagaattat agtaggaaac gaggtgctgt tatggaacga
    40561 acacttgtta ttatcaagcc agacggcgta agacgccatt tggtcggaag catcatccaa
    40621 cgttttgaag caaagggact ggccattgct gaaatgaaat ttgcaacgat gacacctgaa
    40681 ctagcaaaag aacattatca gcacttgact gaacgtagtt tttttgatga gcttatcgat
    40741 tacatgactt ctggtccggt cgtttatctt gtgctggtcg gcgaggaagt gatcgatatc
    40801 gtccgtaaga tggtcggagc aacaaaaggg gcggatgccg ttccaggtac gatccgagga
    40861 gattatgcac tgccggggac tgaaaacatc atccatgctt ctgattcccg tgatgctgca
    40921 acaaaagaga tcgcccgctt tttcccgcca ttcgatacaa acaaaccgtc tgaaaaagcg
    40981 gcgaagtgat acaaatccta aactgttggt ctaactgctg ggtttagcaa tggccagcag
    41041 ttttttctct aaagaattcc tttgattctt ccctaatgta tattcgatca ctgcgaaaaa
    41101 ctcttggtga ttttccgatt tttcttcccc taaagcagca gaaatcagtc gttggtaata
    41161 atccgccatc aatgtttcat aaatcactgt acttctttct ttatgcgcta aactccgttt
    41221 catatcttca ttcacgctac gtgccttttt taagcgacca ttttctatat aaaacaaagt
    41281 caagttcgtc aaaaaagtaa agagatactg ctcgtgatta ttcagttgcg cgatccgtcg
    41341 cattcttttt ttgattttca aataattatt ctcaataaaa cgatcactga atatccaagg
    41401 aaaatctgct agaatagata cttcaaattg cccatactct ggtacttgca tcaaatattc
    41461 ttcaatgata cgacattcat aacgcaaaaa ttcaaattcc gtctcagata cttctgtttt
    41521 tttggacatg tgcagattca aaaccaaata gtacagatct tctgttttct tatagtgcct
    41581 gcggttatta gcaatttctt tgtaaggatc aaagctgtct tcttgaatcc gatctagcat
    41641 tcgtcttttt ttctttaatt tttttggctc atcaagctga tttcgtatcc attcatattc
    41701 ggcaagtgtc atgttcattc gctctaaaaa tgatttcaat gttccaaacg atactttttt
    41761 cactgaattt gtctcgatcc cgactagcga agttttagaa cagattcctt ccgctaattg
    41821 ggtctgtgtc agctttttgt tgactcgaag cttcttaatc aattctccat catacataat
    41881 agttctcctt ttttaattga aattaaccct tggcttttcc agaatgcttg ccaataagag
    41941 gaatgattat ttcaatttaa attttccgca ttcaataaat agatacgtta aaaataaaaa
    42001 atacacgaaa aaaataaaaa aatgtttttc tcataaaaaa taccaacctt caagcatgag
    42061 actgctgtct aatccctgaa ggttggtttg attgtttatt gatcattttt ttactgctcc
    42121 gcattggttc ctgttactgg atataggata gtcgttgttt tattgccgtt ttttgaaaag
    42181 acactggtcg aatgttcacc tttttgcttt tcgattgctt cattacgttc cgcttcgttt
    42241 ttatagtcat attttttcgg atcaatcgtc tcaaatccgt ttggcacata aaaccgcaag
    42301 agattttcct gattcagctt atctgaaaga cttaacgcag tcttgacttt ttcctgatct
    42361 ttggagattt cctcgtcgat tcctgctgct ttcgtatcga tgatttctcc tgtctgatta
    42421 ttgtaagctt ttcctcctag gacggtgtat ttgggcgtca cgaagttccc atttcgaaaa
    42481 gcaactactt gatcgtgctg agaagataat aagtctgtac caaaatgaag ataatcttta
    42541 tcatcgattc ccaatagatg tagtaatgtc ggcaaaacat cgatttctcc accatattca
    42601 tgattgactg tccctttagt gtaaccaggc atatggatca tcaatggcac tcgttgcatc
    42661 tgtgcgttgt caaattcatc ccatgtatct ggatctttac caagagcact tgctaaatct
    42721 ttattatctg tattcgagat cccaaaatga tccccgtaaa tcacaaagat tgaattttgg
    42781 taaataccag attttttcaa atacgtaaaa aattgttcca atgattgatc cagataatgg
    42841 gccgttcgaa cataattatc tactgtgcta ttgccagtat tcaaagatgg aaagtcgaaa
    42901 ttcttgtcat ccgtataata aggcgtgtgg ttggttacgg aaagaaattt cgtgtaaaac
    42961 ggctgttgta gatgttcaag atattgggca gattctctga ataaatcttt atctaatatc
    43021 ccataaccta acgtttcatc ggattcatca aaataagatc gatcaaagaa attgtcatac
    43081 cctaaatttt tatatacatg atctctattc cagaaactag ctacattccc atggaaaaca
    43141 gcacttgtat agccttctgt ttgaccaagg gtcgctggtg ctgcttgaaa gacattatct
    43201 gacccaagtt ctgtgaataa tgagccttga ggtaaaccaa atgtgccagt ttccaacatg
    43261 ttttcagcat cacttgtctt tccctgtcct acttcatgaa agaaattgtc aaaactgatc
    43321 gttgcttgat tctggaaaat actatttaaa aacggcgtga cttcttgtcc gtctaccttc
    43381 atattgatca aaaactgttg aaaactttct aaatgaagga caatcacatt ttttccttta
    43441 gcaatcccaa atgtttcagg atttggctct gcataatgtt tctttgtata gtctaaaact
    43501 tcatcaattc cattactgct tgcatgcgcg cgaacactgc tagtcattcc tgttttgatt
    43561 ccgtcataaa tagtgtacgc atcgattcct agatatttga caatatagga acggtcaaat
    43621 gtccgctgta gcaattgggg acggttggct tcgctcaacg ctaaatttcc tgaaaaaatc
    43681 aatcctgaaa gacaggtaac agcgatagcc atcggtttgc tgacagggtt gcttttgata
    43741 ggtattttct tgaccttcaa ccaaaccagt agcccaatga acacagcgat atccaaccaa
    43801 tagatgacat catggggttt catcaaagaa aaggagcttc ctgacaaccc ttgtgacact
    43861 ttcgaaaagc ctaatacaga tttgactgta atgaaatctg tgaattcccg ataaaaaata
    43921 atattcaagt acaacaaaag cgtatttaaa atatcaatga tcaaaagaat ggctaacgct
    43981 ggctttggct ttttaatata caaagaaagg ccaaaaaaca ataaggtagt cgcaatcggg
    44041 ttgatccaca agataaagta ctggatcgta ccttccacac ctaatgaaaa atctgcatag
    44101 taggcaatga tcgtcttcag ccagaaaaag aaaacagctg tcaaaacgat tgctaaacga
    44161 ttttggcaca attttttaag ttgtgtcacg tatatcactt ctctctattc acattttttc
    44221 ttattttgct cctgaaaaat gaaaatttcc taaaaaagtt gttatcttaa gattttttta
    44281 ttctttctaa agattattcc attcattttt cacagcataa aatcgtttcg gtgtaagcgg
    44341 ttaaaatagt aaggagataa aaatcttgtg gtgaccgatt tactctatag tattcaaaag
    44401 tagtttctcg gtattcgtac aaaaaaaaca tactaagatt agaggggaac atcattgacg
    44461 aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa gaaagttcga
    44521 acaaagcctt gaggactacg agtccctatc aaaaaccgaa cttctttact gtcattttag
    44581 aatcaggttt acgtatgttg gggccatgag cccgtgtata ggaaattgga atcgaaatga
    44641 agcagtaaag ttctttcaac acttaaaaag gaggaaaaca aatgccttac attcttgcat
    44701 tagatgtttc aatgggacac agctacagtg tcctatacaa agacgacacc tgcttatttg
    44761 aagacgagat cgaacacact caaagaggat ttcatgcatt actcgaagag atccagcact
    44821 tgcctgaacg tccattgatt gtttttgaag caacgggtat ttattccaga ccagtcgaaa
    44881 agttctttca agatcatcac ttttcttact gtttgttaaa cccgttagaa gcgaaaaaac
    44941 agatggaaga aaacacctta cgcagttgga aaacagataa atcggatgcc catcggctcg
    45001 cacagactca tcttaaaaat caacgtcaac caaaagaagt acaaagcaat ttttacttag
    45061 agatgcgcga tttagcccgt ttttatcaag aaattgagaa gaaaatcact cgactgcgca
    45121 tggatttaca caactgcctt cagttgactt ttccagagct tgaacagttc ttttcaaaca
    45181 ggctgacccc ttacgcattg acattgatcc gtctttttcc ccatccagat tttgtattgg
    45241 catctactcg gacaaaaata aaaaataaac tgatcaacga aacacgggaa aaaatctccg
    45301 cgaatcgtgc cgagcaaaag gcagatcaaa tcatccacta tgcacagtgt gcctatccag
    45361 ctgttgaaaa agacagtatt cactgtcaaa aaacgatcta ttacgccgaa cttctccaag
    45421 atttactcga acaaaaaaaa gcactggcga cacaaatgat caaaaaagcc gaagcctctc
    45481 cttgcttttt gttgtaccaa acgttccctg ggattggcgc actcacagcc gctttattgc
    45541 tcggtgaatt aggagatatc acacgattta aaacccataa acaattgaat gcctttgtcg
    45601 gaatcgacat ccgacggtat cattcaggta agtatactgg ccaagaccgc atcaataagc
    45661 gtggtaatcc caaagcacgg aaaattattt tcttcaccat tcgaaatatg attcgccagc
    45721 aacgcgcagc tcctaatcat attgtcgatt attactacaa attaaaaaag caacctatcc
    45781 ctaagaaaga taaggttgcc acagttgctt gtatgaacaa gcttctgaaa tgtatgcacg
    45841 ctatggttag ggcacataca gagtacgact atgcgtacgc ggtctcagtg gaccattaac
    45901 taaaccactt acagtatacc acttctttgc ccagatcgaa aattttttac gaacggggct
    45961 ttatttagtg tgccttgatt ttgtcgcttt cgtttacgag ctatttttct tgcacctttt
    46021 acttgactaa tcgtaggaaa gaggctgtga caaaattctt gtcgcagctc cctatttctt
    46081 gatgcaggac agctttttca caacctctcc a
//
LOCUS       DACGLI010000022        43068 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.023, whole genome shotgun sequence.
ACCESSION   DACGLI010000022 DACGLI010000000
VERSION     DACGLI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.023"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            237..1877
                     /locus_tag="IXT22_001246"
     CDS             237..1877
                     /locus_tag="IXT22_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAQ4862626.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="IXT22_001247"
     CDS             2031..3353
                     /locus_tag="IXT22_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAQ4862627.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="IXT22_001248"
     CDS             complement(3415..3846)
                     /locus_tag="IXT22_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862628.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="IXT22_001249"
     CDS             complement(3910..4746)
                     /locus_tag="IXT22_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAQ4862629.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(5291..6109)
                     /locus_tag="IXT22_001250"
     CDS             complement(5291..6109)
                     /locus_tag="IXT22_001250"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862630.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGNSYNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(6209..7534)
                     /locus_tag="IXT22_001251"
     CDS             complement(6209..7534)
                     /locus_tag="IXT22_001251"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862631.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            complement(7703..8632)
                     /locus_tag="IXT22_001252"
     CDS             complement(7703..8632)
                     /locus_tag="IXT22_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862632.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            complement(8880..9230)
                     /locus_tag="IXT22_001253"
     CDS             complement(8880..9230)
                     /locus_tag="IXT22_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862633.1"
                     /translation="MIFENESEEIGRMAEENKVVPFETLVINKEEFEQLFLDFFIQYD
                     RIYDFSSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFR
                     EFRNQIIRSSNIEN"
     gene            complement(9271..9765)
                     /locus_tag="IXT22_001254"
     CDS             complement(9271..9765)
                     /locus_tag="IXT22_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862634.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTIDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKNDTEKPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
     gene            complement(9758..10072)
                     /locus_tag="IXT22_001255"
     CDS             complement(9758..10072)
                     /locus_tag="IXT22_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862635.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDSESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(10288..11679)
                     /locus_tag="IXT22_001256"
     CDS             complement(10288..11679)
                     /locus_tag="IXT22_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4862636.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(11664..12275)
                     /gene="mobC"
                     /locus_tag="IXT22_001257"
     CDS             complement(11664..12275)
                     /gene="mobC"
                     /locus_tag="IXT22_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAQ4862637.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(12279..12476)
                     /locus_tag="IXT22_001258"
     CDS             complement(12279..12476)
                     /locus_tag="IXT22_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862638.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     KMKNEIESDFKCCSLEKNVRG"
     gene            complement(12490..15183)
                     /locus_tag="IXT22_001259"
     CDS             complement(12490..15183)
                     /locus_tag="IXT22_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAQ4862639.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAK
                     NSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQG
                     TKTIDVRENLQSSSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDV
                     RENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIID
                     SEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDSLLKK"
     gene            complement(15464..16477)
                     /locus_tag="IXT22_001260"
     CDS             complement(15464..16477)
                     /locus_tag="IXT22_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAQ4862640.1"
                     /translation="MEEIDKLIAQYAYSKDDVYAEKYLKYPIFLDKHKKYKKMKQSTK
                     KVYMYLKKQNEYSLENSKVDSKGRIFLIFAIEKIAEKSCLTKKTVISALRELEEYKLI
                     TIKKNGFNKKTGKNNPNFYYLLKPEFSEGDFYKKKCIEENLHLPTNQHYSPSEKNTPS
                     DKSTFDGDKSFPLPGEKFLQELNHSSKDFKDFKESQNADFIDSLSVENKKLDEILIES
                     LIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIKSAEKEQKIQLKIIYEI
                     CNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGI
                     DKQ"
     gene            complement(16681..16962)
                     /locus_tag="IXT22_001261"
     CDS             complement(16681..16962)
                     /locus_tag="IXT22_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862641.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(17013..17219)
                     /locus_tag="IXT22_001262"
     CDS             complement(17013..17219)
                     /locus_tag="IXT22_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4862642.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            17383..18114
                     /locus_tag="IXT22_001263"
     CDS             17383..18114
                     /locus_tag="IXT22_001263"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4862643.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            18168..19313
                     /locus_tag="IXT22_001264"
     CDS             18168..19313
                     /locus_tag="IXT22_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4862644.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(19398..19703)
                     /locus_tag="IXT22_001265"
     CDS             complement(19398..19703)
                     /locus_tag="IXT22_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAQ4862645.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(19729..20160)
                     /gene="ruvX"
                     /locus_tag="IXT22_001266"
     CDS             complement(19729..20160)
                     /gene="ruvX"
                     /locus_tag="IXT22_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAQ4862646.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(20157..20423)
                     /locus_tag="IXT22_001267"
     CDS             complement(20157..20423)
                     /locus_tag="IXT22_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAQ4862647.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(20677..21402)
                     /locus_tag="IXT22_001268"
     CDS             complement(20677..21402)
                     /locus_tag="IXT22_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAQ4862648.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(21768..21838)
                     /locus_tag="IXT22_001269"
     tRNA            complement(21768..21838)
                     /locus_tag="IXT22_001269"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21804..21806),aa:Gly,seq:ccc)
     gene            21955..22707
                     /locus_tag="IXT22_001270"
     CDS             21955..22707
                     /locus_tag="IXT22_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAQ4862649.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            22723..23202
                     /locus_tag="IXT22_001271"
     CDS             22723..23202
                     /locus_tag="IXT22_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAQ4862650.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(23453..25033)
                     /locus_tag="IXT22_001272"
     CDS             complement(23453..25033)
                     /locus_tag="IXT22_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAQ4862651.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(25026..25769)
                     /locus_tag="IXT22_001273"
     CDS             complement(25026..25769)
                     /locus_tag="IXT22_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862652.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(25945..26721)
                     /locus_tag="IXT22_001274"
     CDS             complement(25945..26721)
                     /locus_tag="IXT22_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862653.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(26969..27805)
                     /locus_tag="IXT22_001275"
     CDS             complement(26969..27805)
                     /locus_tag="IXT22_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAQ4862654.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(27816..28745)
                     /locus_tag="IXT22_001276"
     CDS             complement(27816..28745)
                     /locus_tag="IXT22_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAQ4862655.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            28937..29290
                     /locus_tag="IXT22_001277"
     CDS             28937..29290
                     /locus_tag="IXT22_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4862656.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(29364..30020)
                     /locus_tag="IXT22_001278"
     CDS             complement(29364..30020)
                     /locus_tag="IXT22_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4862657.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            30246..32180
                     /locus_tag="IXT22_001279"
     CDS             30246..32180
                     /locus_tag="IXT22_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4862658.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(32266..33489)
                     /locus_tag="IXT22_001280"
     CDS             complement(32266..33489)
                     /locus_tag="IXT22_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAQ4862659.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(33483..35381)
                     /locus_tag="IXT22_001281"
     CDS             complement(33483..35381)
                     /locus_tag="IXT22_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAQ4862660.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(35375..36493)
                     /locus_tag="IXT22_001282"
     CDS             complement(35375..36493)
                     /locus_tag="IXT22_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4862661.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(36576..37409)
                     /locus_tag="IXT22_001283"
     CDS             complement(36576..37409)
                     /locus_tag="IXT22_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4862662.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(37402..38319)
                     /locus_tag="IXT22_001284"
     CDS             complement(37402..38319)
                     /locus_tag="IXT22_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862663.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(38546..39670)
                     /locus_tag="IXT22_001285"
     CDS             complement(38546..39670)
                     /locus_tag="IXT22_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4862664.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            39853..40761
                     /locus_tag="IXT22_001286"
     CDS             39853..40761
                     /locus_tag="IXT22_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4862665.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            40902..42515
                     /locus_tag="IXT22_001287"
     CDS             40902..42515
                     /locus_tag="IXT22_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4862666.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT        13394 a         8293 c         6770 g        14611 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaagtta agctcattaa agataattga
     4981 cgatagttgg tatttcaacg atttttgaat agaactaatc actttattaa gtctaattca
     5041 ccttaagtgg ttttttagtc gtattcaaaa acgtattcaa gttgcgtggc gtgcttttga
     5101 taagaaatcg taagaactag ttaatcaaac gacttataaa taatgtaaca ccactgatta
     5161 atcagctata tccaaaaaaa caagcattca ttcagataca tcaatctcta tagaatacaa
     5221 agctttcatt atctcaaacc attaccacaa cttggcaagt cggttaattg aagaacacct
     5281 cattctccac ttatagcagt ggagcaacaa gttgagctat tgttgcaaca gaagctaaga
     5341 attctgtact ccatttaagt ttttttagac tatctaccgc aaacctcagc atagtttttt
     5401 taggcttttc tttaatagct tcatctttaa tggtttcgat atactcctga gcctcttcta
     5461 cctcttcttc aggtaaggaa tcattcaaat tctccaaaag caaatcaagc tttgataata
     5521 attccgacat atcatcaata gaaacaatca tattattatt gtggccttgc tgtatattag
     5581 tgttgtaact atttccaaat atatttactt tattatatat tgaattgttg ctcatatagt
     5641 cctccagtcg tcctgctgca ttacttgcat cttgtaacgt cacaaaaaaa tctctcccat
     5701 gttggtaaat tgattcaacg atttcaaatt ctggatttcc atattcgcgc cattcgtatt
     5761 cttccttaaa gtattttccg taactatggt taaattgcac agaattttta ccaattttcc
     5821 ttagaagttt tatctctctc tcagaaataa aattttcctc aaaagctgat tcaactatct
     5881 gaaaatcact aagaaatgtt cctaaacaga agattgattc attaatagtt tgttgaaaat
     5941 tccatggtat tttgttccaa aaaccattct taattaaagc ctcttttttt tcaacaatct
     6001 gtgattttac attttctgta tatatcttcc aattattgac gtcttcctta atgtccgaaa
     6061 tcgattgacc ttcataagaa gtccctccac caaaaagtcc ttgaaccatt ttatctcatc
     6121 ctctctataa taattactct aaatccaata cttgctacaa atgatagcat ttcgtgtggt
     6181 aacatgattg ccatcgttcc tgttttattt actctgactt caatacttgg tttgttgatg
     6241 aaattttacc aattgattcc atcgatcgtt tcatggaatc tgtatttact attttcattg
     6301 attgtagaga ttgatttatt ccctctgttg cacttctgat acctttagta tcaaagtttt
     6361 gcatgattgc tcgctgagct gataaagctg ataatgtttg acctattgac tctatcgacc
     6421 tcttcatgga atctgtattt aatattttta ttgattgtag agattgattt attccctctg
     6481 ttgcccttct gataccttca gtatcaaagt tctgcataat ttcttgctgg actgataatg
     6541 tttgacctat tgactccatc gactttttca tggaatctgt atttaatact ttcattgctg
     6601 atagagactc tgacaattta gtaacacctg ctaaatcgat attactaaaa taatttccaa
     6661 tatatccttc aaaatcatct gacatatcac taaggtcctc accagcaata tctccagcca
     6721 atattttttg aaaagctttc tctagttgat ttgtatatct cttcaatttc tttattaatt
     6781 tttggtataa agccatttct atttctttgt tatggcttac aatattccta ccttctctga
     6841 ttaaactcat gtctgtttga atttcttcta gcttaacatc catatattta ctaaatactt
     6901 cactccacaa agaatatgaa tcagatatag tgtgactgtt atcttgaaat aacttcaata
     6961 attgatcctg agatatttct ttatacctta caatattctc ttcattttct tgtgtaacta
     7021 aaatataatt ttctccaaag agatattctt caaaatcata taaatctatc cattgtaaaa
     7081 gattctttga gtcaaacttt cctattgctt gtatttgttt tctttttatt gacgaaatga
     7141 tttcatttgg aattgattcc tctgcccagt tatcagaaaa atatgccgga gctaataaat
     7201 agattaattt tcttaatgcc cattcgtaac tatgcaaata cggtaatagt tttttcgaaa
     7261 aaaacaacgc atttgtatct aaaagggtag tgtagtttaa ttttgattta cttgcttcaa
     7321 tattgacctt agctaggaaa atttgaaata tatgtacctc ttttattcct atcttaccag
     7381 tcttattata ttgaaatact acgtgtaacg aatcattata gttctttatg tcaaagccaa
     7441 atttataatt tttttcctgc tcctgaaatc ttaagataga atcactaata tatggtgaca
     7501 acactttcag aaaggtttct tcgatatttt ccattcttcc ttttttagga taatataaat
     7561 attcaacaac ttgcttacta atatgtcatc aacttctttc ctttcaacaa ttttaatttt
     7621 cctattaact tgatatttgc tacataagcc acaactagca aacagaaaga gaactttttc
     7681 tttaccttga taactgtgtt aattactggt ttcttttttc tatttcttta tagtattgtt
     7741 cttctacttt taatattttt ttaacttctc tttttatgtc agcatacata gatatactgt
     7801 tgtcctttcg gttgaagcag tgataattct caccatcaaa ctcataaaaa agcatatcac
     7861 ttgagcttcc atctgaatta attaactgaa atttggtatt gagtagtaat tcatttttct
     7921 cgtcattcaa ctttattaaa ataggtttga tctcttttaa ataattgaaa tatatttcgg
     7981 ttattactaa attaaatttc gctactgtat aaacataaga gatacgtggg gaatctctaa
     8041 attggttata tatatctttc cttaaaacat ctaactcctt ttttaattgt ccgttaaaat
     8101 caaaatgagg cattgctaga atttcatcca aatcaaagta cactctttgt tgatgaatat
     8161 ttactggcag atgaccatgc tgagaataat ttctcatatg taataaaaac ctatacgaaa
     8221 aatgctcatc ataaggctta ctcagaattt tattcttaaa agatttaaaa tctttttctg
     8281 ctaaaaagtt tttcatacaa acttcaatgg attcagtcaa agttttggct gaactaatta
     8341 agtttatcgt caaagcattt atctgataat aatactggtc ttccgttaat ttttcacctg
     8401 tactttcaat taaatcatta gtaaaaattg tgaagtgttt gagcaaatta gttaaattat
     8461 atctaaacac attaaaaagt ttatccaact ctataatatg acgtgttaat tctacataat
     8521 ttaaaaatat tcttttatca gattctgtta ttgtttctaa taatgaatca atctgcctta
     8581 ttagctcgtc atcttgtaaa ttactgacaa aaaacctact atcacttctc ataattatat
     8641 tctcctaata tgattttttc aaaataatca atatgtaaca tagaagtata ctctattgtt
     8701 acatacctta tttcttatta tatcagtatt tctctgtgac acataagggt gtaacataat
     8761 tattttaaac gaaatgacta caagtagtca ttgaagcaaa tctccataag acatttgtaa
     8821 aatcttttaa aaagaagcgt cgaaagaagg aacttttctt caacgcttct tttattgact
     8881 caattttcaa tattacttga acgaataatc tgatttctaa actctcgaaa aacttcttgt
     8941 ggttgataat agtctggatc tatttcaaat gtttctgaga ataattcatt gaatttttct
     9001 actgaaataa tgattttacc attcttctct cgactgtttt ctattatttc tgcttctaat
     9061 tcaaataaat ctagtgacga actaaaatca taaatcctgt catattgaat aaaaaaatca
     9121 agaaaaagtt gctcaaactc ttccttattt atcactaatg tttcaaacgg aacaacttta
     9181 ttttcttcag ccattcttcc aatttcctca ctttcatttt caaaaatcac aaaaatgata
     9241 ttaacttaaa agccactaac aaaataagac ttacaaagta aagggtaatc caacaaaata
     9301 accattcgct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
     9361 gtaatttact gtttcttctt tgtcactttc aatatactct ggattatcta atatcatagc
     9421 atactcataa agctcttcac catccttatt ttcaatcgac cattgttgtg gacgtattgg
     9481 tttttctgta tcatttttaa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
     9541 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     9601 ataagtttca cctattttta aatctattgt tacaattttt attggctttt cttctggaaa
     9661 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     9721 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     9781 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatca agcttttcaa
     9841 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     9901 cagaatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     9961 cacgaaacat atttgccttg gaaccaaaaa ctcctttgtt ttggttgtaa aaattgttga
    10021 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
    10081 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
    10141 accatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
    10201 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
    10261 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
    10321 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
    10381 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
    10441 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
    10501 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
    10561 aatcgtgtat tcttgatcat cttctaaaga cattgtgttt acaaaatgct tgtctacctc
    10621 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
    10681 ttgtgcgatg gaatctaatt ccacaaaagg tacatttaac tcaccagttt tgtaatttac
    10741 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
    10801 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
    10861 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
    10921 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
    10981 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
    11041 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
    11101 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
    11161 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
    11221 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
    11281 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
    11341 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
    11401 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
    11461 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
    11521 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
    11581 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
    11641 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
    11701 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
    11761 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
    11821 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
    11881 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
    11941 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
    12001 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
    12061 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
    12121 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
    12181 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
    12241 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
    12301 agagagcaac atttgaaatc gctctctatt tcatttttca tctttaattc ttcttgaatc
    12361 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgctttctt tactgattca
    12421 cataattcgt caagttctaa gaaatcatgt gtactaatct gtagaattaa ttgcatgaca
    12481 atcacctctt tattttttaa gtaaactatc gaaaagtgga ttaggatcat taagtgtatc
    12541 tctgaataac tcgttgtctt cataggtaaa ccttcgtctt ggttttgatc ccttatcatt
    12601 ttcacggatt tcactatcaa taatcactgt ttcatgattt gaatcaaatt ttttcgctga
    12661 ctttctgtct tcaacgatat tgattttttg tgttttttct ttcatttctc cactatcttt
    12721 ttgaacgttc tcccgaacat ctactgtttt gaatccttga ctacttgtag aactttgtac
    12781 attttctcga acatctactg tttttggttg acttgcactg ctaccttgca cattctctcg
    12841 gacatccact gatttaaacc cttgactact tgtagaattt tgtacatttt ctcgaacatc
    12901 tactgttttt ggttgacttg tactgctact ttgcagattt tctcgaacat caattgtctt
    12961 agtaccttga gcatttgaag aactttgtaa attctctctt acatcaacat tccgtccaac
    13021 atgaccattc agtgaacctt gaatattttc tcggacatct actgatcggc caccatgact
    13081 acttgtagaa ttttgtggat tttctttgac taatttttct aatcctgtat ttgaattttt
    13141 agcttcttga attctttctt tggtcaacgc ttcttttccg tcaatattag cgcctgtccg
    13201 cccttctaca cgtttcctta acattatttc ctcgcgattc attgcttcag gcgtgtattt
    13261 cgcttcatga cgcttctgat taattaattc ttcagcagac ttagcttgac cgtgcatagc
    13321 atttttacgt tcttcaatat cttgttggac tttttgctga attgcactta caggattatt
    13381 attcgattca gcattatttt tcattgcttc acgcatacgt tcagaactag acataatact
    13441 atcggcattt tcaaccttag caccatcttt tctatccgaa agacgtgttg gcatggaatc
    13501 agcatatttt ccagtttcat cttctttatt tttagctaac ataggtttgc tatttttatt
    13561 aatagcggac acagtaccat catctaaacc ttctttaaac ttactcttgg tatcattagc
    13621 tatatcacgc atactcttaa atggttttgt tgctctttca ctagccattg tagatccatc
    13681 tgaagctaaa cctgataatc cacgttcatg agcataccca agcgctttcc ccgttttatt
    13741 agctttttta gaaagtgatt gtccaaagtt gcgttcaggt tttcgttctt ccccttcagc
    13801 ttgatcgttt ccaccattat ttttcccacc tttagaccgg ttcataccac ctgttccttt
    13861 acggaatagc attgcaccca ttccaaaagc agaagcaagt tgcccatagc cttctttgag
    13921 tccaatatcc acaccaaagt atctcatgac tgttccactg cctttgatta aaacaaacac
    13981 agcacagata taagcaattg tttttataaa aatatttgct gagatacctt cgccagtatt
    14041 taggtaattt atgaacattg caaacataga taaaccgaac ccttgaaatc cgactgtcaa
    14101 atagcactgt aaaatatctg acaaaacttg ttttgatcgt tgtcctgttt ctaagtcagt
    14161 agcaaatact aaaactccga gtacacgttt aaatgctaac tcgagtattg ctgtaattat
    14221 aatgaaagca ctaaaaacat acgctaccgc taaagcaatc aatccaaaag aaattcccca
    14281 caggttcgct tgatagcgat aatatcctga tttgatacca tcaacaaagg ttgataaaaa
    14341 attatctgaa aatttagtag caacaaattc attatcagaa ttttcaacta attcataacg
    14401 cagattatca gctgttgggt tctctttttc cattttatca attacattat ctgtcaatac
    14461 ttgcgtaaga tccgttttcc agaaattttc ttttgttaga ttatttcggt catttgtttt
    14521 atcaattgtc gaatattgat ctgtcttatt aatataagct aaatctgtca ctccctgctc
    14581 aatcaatgac catgctacac cgccatcttg attattgata ctagttgcgt cattataaag
    14641 agtctttgca aacattattc ctgaaagttt ttctgttgat ccaatcaaag tcggcattaa
    14701 aagaattaat gctacagaca tcactacgtt cattccaacc gattttaaat ccactgttcc
    14761 ttttccagta atcattttgt aaccaacaaa catcagtgaa agtatcatta aaccaataac
    14821 aactgtactt aagaccgatt gataaacttt attcattccc gtactttcaa taaagctaaa
    14881 caaatctaac acttcgggaa tcatattttg aataccatct acaattgcaa acatcgattt
    14941 tataacagac caccctatcc acaatccaaa ctgactgtaa aaatttccgt tatatttttt
    15001 taaatacgat tgatagacag gattattcaa aaattcagtt tgactttccg tgtcatcaaa
    15061 ccaattgaaa atgcttgctt ggacaacatt accggtgaaa acaacgataa acattaaaac
    15121 aagtatgctc aaagctaacc agtgtatttt tctactggca atcttttctt taactatttt
    15181 cattattacc tccctcagcc cattttctga gactctcaga gagcttctga gctgtttttc
    15241 tgtcaattat gatatgagtt acacaattgt cattttcaga tcttaaatcg agaactatag
    15301 tgttgaagca aatagtctcg attaattcga gattatctgt attttgatct agacaccaaa
    15361 cttgatctat taaacgattt tcaatcaaaa taacccctcc tatattcaaa gttctcaaat
    15421 gaagcggaga tacccctcca cttcatttga ctcaattcta ttcttattgc ttatctattc
    15481 cttcactgat ttgcaattca attagttcta acgctttatt ttttagagaa gcaaagatat
    15541 aatcgtcttt ttgtttgata cggtgatctg tttttgctct tcgtatcaag tcacgtaaag
    15601 tcattgatag ctgttctcta acataatcta caaaatactt gttattacag atttcataga
    15661 taattttcag ttgaattttt tgttcttttt cagcagattt aatcgcatat ttgaattttt
    15721 tataccagtc ataaaattga ctgtaatcgt tattacccac taatttcaga cagtttacaa
    15781 tattatcccc ccatacctga taaagccatt ctttttcaat taatgattca attaatattt
    15841 catctaattt tttattttca actgaaagtg aatcaataaa gtcagcattt tgagattctt
    15901 taaaatcttt aaaatcttta gaagaatgat taagttcttg taaaaatttt tcacctggaa
    15961 gcgggaatga cttatcacca tcgaatgttg atttgtcgga aggtgtattt ttttcacttg
    16021 gactgtaatg ttgatttgtc ggaaggtgta aattttcctc aatgcacttt tttttgtaga
    16081 aatctccttc gctgaattct ggtttcaata aataataaaa atttggatta ttcttcccag
    16141 tttttttgtt aaatccattt tttttaatcg taattaattt atattcttct agctctctca
    16201 aagcgcttat taccgttttc tttgttaaac aagatttttc agctattttt tctatagcaa
    16261 aaatcaaaaa aattcttcct ttgctgtcaa cttttgaatt ctctaaagaa tattcatttt
    16321 gttttttcaa atacatataa actttttttg tactttgttt catcttctta tattttttat
    16381 gtttatctaa aaaaatcgga tacttcaagt atttttcagc atatacgtca tcttttgagt
    16441 atgcatactg agcaattaat ttatctattt cttccattta ttcctcttct ttctaataaa
    16501 tgttaaaatg tagtcaaata aagttttctt agaactttat tgtcgagtgt ttcctgtggt
    16561 cgccaaactg tcgggaacac tccttttaat ttttttcaaa gtatttttat attttctata
    16621 cttcatcatt attcaaacaa acacttcctt ttttctatca aaagcacgcc acgcaacttt
    16681 ttatacttca tattctttga taaaccttgc taattcttct tttctaataa attgacaatc
    16741 tccgattatg cttactttta aacctttctc tctgataaat ttttttaatg tacttctgct
    16801 acagcttaaa tacttacaag cttcccccaa tctaaaaact tctttgctta gagatgtttc
    16861 aattcgaact tgatctactg cttcttttgc aactcgatag aaatatcttc gcaattcttg
    16921 atctaaatcc gatggaagaa taacttgaat ctcagatttc attttctttg cccccactaa
    16981 tttgactaca tgtattcaaa ttcaactttt cgtcactttt cattaaaaaa aatttgatca
    17041 attgtgatat tttcaattcc tttttctttc acaagatact tcaaaataat catttcttct
    17101 ggagaatagt ttgttttacc gctttctttg tttcttaccg cttgtactga aatgccatat
    17161 ttttcagcaa gttcagattg tgataatcca caaaactttc taaaatcttt aggcttcatg
    17221 actcctcact cctccttctt ttcaactttt cgtcactaaa agaataacat atatttattc
    17281 ataccgcaac gtaaaattca acttttatct actttttcat ttcattatat gagaatgtag
    17341 tgtaaactgt agaatagaat agatgaaggt ggtgaaacca ttttgtttga taaaaacatt
    17401 aattctgaaa ttggaaaacg aatacaagaa atacgtgttt ctttagggta tactcttgaa
    17461 gaatttggcg aaaatctgac acctcccgca agcaaaagca atgtttctag atgggaaaaa
    17521 ggaaagaaca tacccaacaa agcgcggcta ctaagtattg ctaaacttgg tggtgtttct
    17581 actgaatatc tactgacagg taattctcaa aaaactaaga aatatatcaa gtatttattc
    17641 aatgagattt tttttgacaa cggtaccttc cataacaaat tcaaagattt cggtaaagac
    17701 agagataggc ttggtctata tgacttattt ttagcagtat cgaaaacata tagtctagat
    17761 aaatcacctt ctttaaaaga taactttgta gaaatgatta tagatgatgt atataaaaaa
    17821 ctcttgcaaa ctgataaatc agatgaccaa ctcatcctgg gtttcatata tatttgtctt
    17881 gatgaaaaac tttcaaacag acagaaaagt cttaaaagta tcaattatga ggtattcaat
    17941 tatttaggtg ttgcatttgg tttaattgat agcgaaatca aatctacaaa cgcaggtaac
    18001 gatgaagatt tattaaatta tttaaaagaa ttaacatctt ttattgatga aataaaaaca
    18061 actacattca acaaaaaaaa atattttcaa aatcaatatg atatagaaga ataaagatta
    18121 cattttccta tcaaaagcac gccacgcaac tgataggagg aaaaacaatg gcaacaatta
    18181 aacaatatga aaagaaagac ggaaccaaag cttggatgtt tcaaacatac cttggaatca
    18241 gcccgctaac tggtaaagaa gtccgtacta cacgtagaaa ttttaaaaca aaaaaagaag
    18301 ctcaaataga gcttaataga ctacttgtag actttgaaga gaatggactt aaaagggaaa
    18361 cgaacgaaac tttccaagaa gtgtatgatc tctggtatga aagctataaa actactgtaa
    18421 aagaagtcac tcaattaaaa attgagatca agtttaataa atggattctt ccaaaatatg
    18481 ggcagtttag aattaaagaa attactacaa aacatgttca gaagatattg aatcagtggg
    18541 ctaaaacaac agatcaatat aaagtcctac attctaccgt aagccgtatt ttcaaatacg
    18601 caatgactct agggctgatc actaaaaatc cctgtgagct cgtaatcatg cccaacagaa
    18661 atgttgaaaa aaagaaggat actgtcaaaa tttattcacg agatcaatta gaaaccttat
    18721 ttcaatattt ggaatccaaa agaagtacgt atagggcaga gtacgataaa actttactgc
    18781 gctttctatt ttttagtggc tgtcgaatca gtgaggcttt agccttagac tggtcagata
    18841 ttgactttga ttcaaacacc gtcactataa acaaaacctt aagccaaaca aaatatgggt
    18901 acaaaatttc aagtccaaaa acgagaaata gctatggttc cctatcttta gacaataaaa
    18961 ccattaattg gctaaagaaa tggcaaatca atcaaaaaag atatatgtta accctcggga
    19021 ttactgatcc aacaatgatt ttttgtggaa tctacaaaga aatcattact aaacacgcta
    19081 tctattctcg tatgatcaca atctgcaaga attctggtat tccatttcta ggtaaccatg
    19141 taaccagaca cactcatgct agtatgctgt tagagtcggg agtctccatg aaggaagttc
    19201 aagaacgcct tagacactca tcaatcaaat taacaatgga tacctatgct catctaacta
    19261 aagaaaccaa agaaaaaacc gttgaaaagc ttgcagagca cctaaatttc tagcggaacg
    19321 tattcaatcc cgtattcaat tcaaaacaaa aaaaagctga acccttatct accaagggtt
    19381 cagctatcat ttacagctta ttcttcttct tccgccatga atgtattgaa tacttcttcg
    19441 atcatatccc attctgcgtc tgtttcgatt tgttctaact cgccttctgt tccatcttcg
    19501 ttttcgatgt atgcataagc ttgtaattct acatcttcat cttctgaaac accagctgga
    19561 tataaaagaa catagttacg tccaaattct tcttgtccgt caactgttag caagatttcg
    19621 tataatgttt catttccttg gtcatccacc aatgtgatgt gttcgtgtcc ttcgtgttcg
    19681 tgggaatggt tatgttctgt cataagatta cctcttttct ttttattatt aaaataattg
    19741 cttacctgag ccgtctaaat aattttgtaa aatcatcaca gctgctaatt tatcgatgac
    19801 tttttttcgt ttcgctcttg aagtatttgc ctgctctact agcatacgtt ctgcctgaac
    19861 agtggttagt cgttcatctt gataatcaac cggcaaggag aatagttctt tgatcttctc
    19921 tccatatgac atggaagctt ctgcccttgg tccgatggaa ttgttcatat tcttaggtaa
    19981 tccaactaca aaacggtcta cttcgtactg cgccactaat tccttcaacc gatcaaaacc
    20041 aaactcttct tctgcctcat tgattcgaat gatttctact ccttgagctg tccagccaaa
    20101 gggatcgctc acagcaacgc ctactgtctt agaaccgaca tccaagccca ttactctcat
    20161 aaattcactc catgatttga gaggtagtct ttgacaatta cttccatgat ttcatcgcgt
    20221 tcgtgacggc gaatcaaatt tcgtgcatca cgataacgag gaatgtaggc cgggtctcca
    20281 gaaagcaagt agccgacaat ctgattgatt ggattgtagc ctttttcttc caaagcccga
    20341 taaacaatcg ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa accaaaacgt
    20401 acggtttcat ctgtaaaacc catgattcta cacctctttc ccgcaaggta attccagctt
    20461 accttctaca cccttatttt actcgaagaa agggaaaact acaaacaaat attccaaact
    20521 tctgaataaa ttaagaaaca cgatttgtct gatttttcct tttttctgtg gctttttcaa
    20581 aagccctctt tccataaagt atacgctata tttctttgaa agtatgtttt tacacaattt
    20641 tttcataaag ttcataaaaa attcgaattg ctgctactaa tttttcgttt tcgttgcttg
    20701 ccctgtctca taattgatgg tgtagccatc ttgaacattg tagataaaga cattgaattc
    20761 aatttttttg tcttcaatgc tttctgcttc caactgcaca cctcttgcta ccagttcatt
    20821 tccctcgaaa tgaggagtga cacgatagcg tacatgatga tttgtttcct tgatatatgc
    20881 cgcaatatca ttttcgtggg caagcatgta cggagcattc aacgaacgtg tccctgtcat
    20941 taagttttta atgttattat tttgaccagt caactggaaa ccaatcaaat ggctgcggtt
    21001 gtataaccat tgtccgtcac ttaatttctt ttgtttccaa cctgtcggat caatatacaa
    21061 aggttctctc ttttcagtag gaaacaagtc ttttcccaac atcgcattgg cttgtcctac
    21121 tctgttcaat ttgtctatat ttgaatagct ttcccatgtc cctttggaaa gactaagatc
    21181 ctcttttgta aactccggct gattcccatt gatttctatt tcttgatgtt ttccatcata
    21241 ttctggcaca tccgctactt gagaagcttg cggtgtggaa tcaaaaatgg ttgtaatttg
    21301 ttggaagata tctgaatctt tttgtgtggt ggaaataccg agtgcccctg caatcacagc
    21361 agcgacgatc cccacgatcg ccttggttgt ttttttgctc atttctttac tcctttacta
    21421 acagttccct aaatcttaac atatgttccc ctataaataa atactggaaa gaaatagaaa
    21481 cagtaaaaaa ataaaaccag tttttagacg gcttaagaat acaaaaaaag agacggattc
    21541 atcgtctcta ctcaatcaca aaacactatt tacaaggtat ttattatcat tcaaaaaatt
    21601 tttcttaata ctcaaaacta aacggcttct gtacgacctc ttggtaaaca gtgttcaaaa
    21661 gcttgcatct gcggtaataa gtccaaccaa gtcaaaaaca taagaagctt ttttgcttga
    21721 ctattcttat tacttgatgc agggcagctt tttcacagcc tcttttaagc gggtgacggg
    21781 aatcgaaccc gcgacatcag cttgggaagc tgggatttta ccactaaact acacccgcga
    21841 tacaaaaaca gtatacgcct ctttcactcc ttcctcaagt ttttttattc tttacgcttc
    21901 cgatatgttt tgtagtaaaa taaaactaat caatcaatta ttggagaaga tgctatgacg
    21961 ggaaaagaat tagatctgtt gctggacact tgtttactcg ctgggaaaat catgatggaa
    22021 agcaatgcgg agatgtatcg ggtagaagat acgatgagtc gaattgcttt agcttctgga
    22081 aatttccgtt tggtcagcta tgtcactcaa accggtctct ttattggtct tgatcgtacc
    22141 tcgaccatcc gaatggaaca aattaccaac cgttcgatta atttagaaaa agtagtaaaa
    22201 gtaaatgatc tttcacgtaa atatgttgct tcagagctaa cattagaaga actttactgc
    22261 gaactgcaag caatcgaccg agaccgttct ttctttcctg tctggttgca aatcgttagc
    22321 gcggcagtga tcagtggaac aattatggtg ttatttggcg gaaagatgac cgatttacct
    22381 gtgactttag tcattggagg attgggatac gcagcttatc tatatagttt gaaatttttt
    22441 agaatcaaat ttttatcgga atttttatct tctttattga ttggcatagc cgctatctac
    22501 agcgtacgtt ttggcttagg aagcaatcag gatctaatca ttatcggatg tgtgatgcct
    22561 ttagttcctg gagttcaaat tacgaacgct atccgtgatt tgctagctgg acattatgtc
    22621 tcaggagttt ctcgcggaac agaagcgatg atgactgcta cgatgatcgg ttttgcgatt
    22681 gcttttattt tccagctttt ttattaggaa aggaacacaa gtatggggac gatatttatt
    22741 cagttttctt ttagtttttt agcgactgcg gcatttgccg ttattacaaa tgtacctagg
    22801 cgttcattga tttgttgtgg tctttctggt gcttttggct ggatgatcta ctggatctgt
    22861 gttcaaatag gcggatctgc tgcttttggt tcattgcttg gttctttagg agtagcattc
    22921 atcagcgatc ttttctctaa acgtttgaaa atgcccgtaa cgattttcaa tattcccggg
    22981 atggttcctc tagtccctgg tggtttagct tatcaagcgg ttcgaaatct cgttactgaa
    23041 tcctatcgag aagcggctca ttatgcggtc caagcaatta tgattgctgg agcaatcgct
    23101 ttaggtcttg tattatcaga agtctttaac cataacatcc gtaatttcaa agtaaagcgt
    23161 gacgcaatca tgatgaaacg aaaaaaacgg ctttttaaat aaacgaagtg taacaaagaa
    23221 aaggttgtga aagagacgtt cagccttgag cgatgacaaa atatctcaca aacattgcga
    23281 caagtaaccg caggagcaat aagaagtaat tatgagtatt aaaaaaagtt ttgtaaaaat
    23341 agcttctcac atttttacat aaaattgact taatactgag aaactgactt ttgaacaccc
    23401 tctatctgta aaaaaggggc tgcgacatga tttttgtcac ggcccctctt ctttattcaa
    23461 attttttcca aaacgttcgt tgataataaa cgatccatag agcggaaagt attagaacta
    23521 aaccgatcac aggaatattc actaaccaaa atggataaaa caaagccaac attccgtata
    23581 agacgataag aataatactg atgatcaatg aacccatcat agttgcgact aaacccaaac
    23641 ttcctgaacc tctgttaaat aattggttaa tattggtcca gttcagcagc agcaaccgat
    23701 aatctctagc gaaataacgt agtgacaata agtagcagcc gaataaagaa ccaaatagca
    23761 agctagggat aaaaaacaaa ggcagctgaa aagacagtcc gcttaataat gcgatcccac
    23821 cagttaaaaa actctgcaat atccatccga atctgaactt ttcttttaaa tattggttca
    23881 tagagattgg caaagaacgg ataaacagaa aattttcttg atccaaagaa ataagattgc
    23941 tgataaaaga agtctgatta actgttaaga aagccaatgc gatccctacc aggaaaacaa
    24001 caccgattaa cttattatct aaatcagtta attttatttc gcctcctagg gcaaaagcaa
    24061 gaataaaaat gattggagtt aacaaggaag aagaaagaac ttgcataatc aaattaggtt
    24121 cttttactaa ttgagcattg taactaaata aaagctgatg cacattttgg ttctttttat
    24181 gggttctttt tattttgaac tcactgtttg aatcagtcag ttgctctgta agctttggta
    24241 ctatcagctg ttttacagca aggaaaaatc ccagagccgt gatagctagt attccccaac
    24301 ccaataaacc ttgttgagaa agtggctgac tggcagcatc atagaatggc aataatatcg
    24361 aaatcggatg ccgatctgtt aactcatttt caatagtccc cgtttgatga ttcatccaca
    24421 tgattccagc aaatgcgatc agcatcgagc tgccaagcaa gatactagaa actgtttttc
    24481 tatgtttttt aaacactgct gttcgagcca aaccaaaaac aatcaaacta gccagacaaa
    24541 aaagaataat caaaaataga gaaaacaaaa ggattgagat aatgatagta agcaaaatcc
    24601 ctagatcagc tcgccatccg gttaaaataa acatgactag aagcggaaaa acaaaaggaa
    24661 tgatggtcaa agcaactacc aaaatctttg ctgaaaaaac ctgttcttgt ccaaaaggca
    24721 gaggcaaaaa tacttgcagg tcatttcctt caaaaaagat attataaatg actgatatac
    24781 tttgagttaa acctaacata ccaaaaagtg ccacgtaata agtaaagaaa cctggcaatt
    24841 taacaaagtt catagcaaac atagcaaatc cgtaaatcag taaaaaaatc agccctgaaa
    24901 aaagattttg agacaaaaga tagatagtta atcgctttcc cttttttcct ttctctcttg
    24961 ctttattcgt gagctgtgga ttaacatata aaagattaac tcgaattaat tctaataatt
    25021 gtcgcttata catacggtcc atctcctgtc gcttgccttc cagccatttt caaataaatc
    25081 ttttctagcg tttcatcagg tgagccattc aataattcac taactgcccc ctgataaatc
    25141 aattcacctt tcttcaaaat agccagttta tcgcataact gttgtgcggt atccaataca
    25201 tgtgtagaaa aaatgactgt ttttcctttt gcggcatgag ccttcatcat ttctttcaaa
    25261 tcaaatgctg cttgaggatc aagtccttgc aaaggttcat ccaataccca aatatctgga
    25321 tctggcagca acgtgccgat caaaatcgtt ttttgacgca ttccatgtga aaaacttgcg
    25381 attgtttcat tttgatgact atacatatca aaaagcgctg tcaattctgc taaacgcttt
    25441 tctttttttt gtgtgtctaa ttcataggca gctgaaatca agtcccaata ttctccagcc
    25501 gtcaattgta aaaaaatatc tggggaatca ggcacataac cgattttttg tttgatactc
    25561 aatcgatttt ccgtcaattt cattccatct actaaaatcg ttcccgatga tggttcaata
    25621 atactaacta aacttttaat cgtagttgat tttccggcac cattatgtcc taaaaatcca
    25681 aaaatttccc cttgtcttat cgagagagac aagtctttta atgcttgttt tttcccgtaa
    25741 cttttactta cattgatgaa ttcaatcatt tctgtactcc ttttgtttgt tattactttt
    25801 tattgtaccc ttcgttattg gtggagtaaa tgtcaaaaag agtgcataac aaaaaaggat
    25861 agaaacgact aggctgctac ttgggttgtt ctcttctaca ggaaaacact cttctaacag
    25921 gtaagatatg agtctttgtt ttctttaaaa tgattcattt tctatctttt cttgcataaa
    25981 attctttagt ttatcaatac ttctctttcc catctctagt tgttctccat ttgcaaatgt
    26041 tactatttcg tttactctgc taatagatgt aatgttttca gtattaatga tataagcttt
    26101 taaatcttta cataaatact catattcgag tgatttttta tattttttaa ttgtgccgtt
    26161 tacgagaatc tcttcatctt tcaatactag gcctatttta tttttataac ctggcatgct
    26221 cattagataa aggatttcat cgtaatggat atagtgatcg ctattaccat aacggacagt
    26281 tgtccacctt tttttcgtag catgttgaac aggatagttt tctttttctt tcaataagta
    26341 actttggatg ctttttttat ttttttcata agtgaattct tttatcaaat aaccactagg
    26401 cgtaatcttt cgattaataa cagttattgc tttattcgga tgagacgtta gataaacaat
    26461 tttacacttt tcattctttt ctctaagcat ttcgcctagt tcgataccgc tataataggc
    26521 gttcaaatcg atgtctagga aaaaaatatc tgaggaatag atttcattat ttttaatgaa
    26581 ttcaacaaat tgtataacgt tcaatccctg aacgatctca aatttccaag gacttaataa
    26641 aattctggat tcttccaaaa tttctactag cattttttca aaaaccaaac tatcatccaa
    26701 aataaatata cgcgttacca taaaaagtac ctccactcga tattttacta tcaaaatcat
    26761 ttcatacaac ttttcaacat acatgttagg aataaattgt aattctcttc acaatctttt
    26821 ccaacacctt tgaaaccgat atcaaatact ttcaggatgc tgcttctaaa ataaatatca
    26881 aacaaatgaa tacatcatgc aaaaaaagcc agacaaccga cgtccttgcg tgtcagctgt
    26941 ctgagctatg tttatttatt ttgttctttt aaaaagaacg atacacatac tgatttttcg
    27001 gagcagagac tttctcagcg tttgtaacaa ctacagatgg gatttcacgc ttgaatggtt
    27061 gataatagtc tgattggatg gttccttcta ttttatacca ttcatcattt ttaaccgtta
    27121 ctccttccgg catatgcgtc aacaaaccaa agactcctga atctgccaca caatggataa
    27181 tgccgaatcg gaacaagaag atatctgtat tgctatcgtt cggtgtttgg taaacaaatc
    27241 cttcatagct gatttttttg ccaatgaatt cgctagggta attataaatt agctccataa
    27301 cttctaaata gttttcatct gtgatcttga tagtttgctt atccccatac ttttctttca
    27361 actcattcat ttggtctaag tagtctgatt tgttgaaata aatactggta tccggcttta
    27421 agtattgtgt ctgcatctcc ggatccccta ctgattcttt acttactggg aaattaaatc
    27481 ctttggcttc tacgatcgta gtgtcgagac taactgttgg aaacaacgtc cccacgatta
    27541 ctggcaaagc tagcagtaca taagcgattc cacgttgata aggttttgac aacccatggt
    27601 catgatcgtg ctcgtgtgcc ttttcttctg cttttccgtt tttgacccac aaatacagct
    27661 gaactaaagc caaaagagca gataaaatca ttgaaagaat agctaagtag cgataatgga
    27721 cattgatata ttgatcgagt ttgccagaaa cttgcaagta catcatcaat tcgaaatacc
    27781 cagataaaat caaaaaccgc agcatatttt ccctcctaaa taaataatgt gaatccaata
    27841 acgctaaggg caatcagtcc gatcagcgat aaaataaagc gtcctgtaaa atatcgtttc
    27901 atcatcagta gatttttgat atcgaccatt gggccaaaga ccaaaaaggc agctacaggt
    27961 gctgtgccga acagacttaa caaagaagat cctataaacg catctgcttc tgagcaaaga
    28021 gacatcgtaa aggccaataa cagcatgatg ataatggcta aaatctttgt tgagccgagc
    28081 gttagcataa ttctagttgg taaataagtc tgcatcgcag ctgcgattaa tccgccaatg
    28141 atcaaataac gacctgtatc aaaaaattcg tcgattgaat gtgtcaacac atgcccagtt
    28201 tgatggatca gctgattttt tggttcattc ttctcacttt gttcttcttc atggacatga
    28261 tgatggtgat tttctgctac tttagacgtg attttttctt tcaatacagc gtctttttga
    28321 aaataggcaa gccagacacc aatcacaagg gcaacaaaaa agctgcctat cacccgccag
    28381 cttgccatct gccaagaatt gccaaatgcg ataaaagtgg aaaaaatcac gattggattg
    28441 atgatcggag cagtcagcat aaaagcaaac gctgtgtgaa ctggtacgcc ttttttaaca
    28501 aattgatgaa cgatcggtac gatgccgcat tcacatgaag gaaagaaaaa tcctaagatc
    28561 gaaccagtaa aaatagagaa gatacgattt tcaggaagcc atctcttcac acgttctggg
    28621 gtcaaaaata cttgtaaggc gcctgagata agacagccta ataatacgaa aggtaatgct
    28681 tcaataacga tcgataagaa aatcgtactc atctgcaaaa ccgaatttgg aataaaagaa
    28741 aacatgagtt tcctcctttt tatttctagt tcattcgctt tgcaaatata cgcttttatt
    28801 caaaaaaaac aagttgctct gtaaattttt acacaactct tattttttac caaagcactt
    28861 caattgactt tttctgttat tcccattaaa ttaaggtctc atacatatca cttctatcat
    28921 aaaagggaga ataaaaatga aacaaaccac taacttgact gaagttcaag acatactgca
    28981 acagtcatcc gttgccgtca tttatctttc gatgcctaat tgcagtgttt gtcacgctgt
    29041 tcgtccacga ctagaggaac ttctcacaca ttatgatatt ccggcacttc atttggatgc
    29101 atttgaaaca ccagaagtag ctagtaaatt tgaagtgctg actgcgccag ttgtcctgat
    29161 ttttcatcaa ggaaaagaag tctttcggca agcacggttc atcgacttta aaaaaatccg
    29221 ttatctacta gatgaactga cagcagaaga tgattccctt tcttatgaag aaatcttccg
    29281 aacaaaataa tcgttgtcca aacagaaaaa agcgattgaa caagtgaaag ttttgccttc
    29341 atttgttcaa tcgcttttta tttttattct gctgtatttt cggaatgcgc atttgcgtca
    29401 gaatgcaaga aatagatcaa ggtttgcaat tcattcgtca aatcaacatt ttggatcaat
    29461 acatctgacg gagcattcaa tcgagcagcg gtaaagttca agattccttt gattcctgct
    29521 tccgttaact gattgactac ttcttgtgct ctttcagcgg gtatcgttaa aattgctact
    29581 tcgatttgtt ggatcttgat ttgttctgac atatcttcca ttggataaac ggggataccg
    29641 tctacgatgc gcccaacgat ttcctcattc acatcaaaag cacaactgat acgtatgcta
    29701 ttactttgat ggaatttgta ttttagtaaa gcacttccca agttccctac accgatcagc
    29761 gcaacatttg tcaattgatc gtcgtttaat gtctttgcaa aaaagtgcat aagatcttct
    29821 acatcataac catacccacg ttttcctaat tcgccaaaat aagaaaaatc tcgacggatc
    29881 gttgcactat ctacttgaac ggcttcactt aattcagttg aagacacttt tttctttcca
    29941 gcattattta aaatccttaa atagcgataa tacaaaggca gtcttttagc tgtcgccttt
    30001 ggaataatat gatctttcac gaaatgacct ccacgtattg tctaattaca tctttgattt
    30061 ctccatcata gcagtattta taggaaaaaa tcaattccat tgctcagata ttgtgaaatt
    30121 ttattcttta ttcatttatt tatcatttct gcaaatctcg cagtataatg gaatttatgg
    30181 tagactacta attgaaaaat agttttttat ttgaggagaa ttcacaaagt agaaaagagg
    30241 attccatgat attattacaa gccaatcaga ttgctcgcca ttttggtgca gaagtcttat
    30301 ttgaaaacat acatttagaa atcagtacag gcgctcgtgt cgctttagtt ggcagaaatg
    30361 gcgctggaaa atcgacttta ttaaagatca ttgctggaat tgaagcacct gatgaaggaa
    30421 agatcgctaa aaataaaaca gcgactctcg gatacctcgc tcaggacaca ggacttgatt
    30481 ccaatgaaac agtttggaac gagatgctga aagcttttga acaagttaga caaatggaag
    30541 agcggatgcg cgagctagag attttcatta gcgaaggtac gccagacaca cctgcttata
    30601 gttcttattt aaaagaatac gaccggctgc aacacgattt ttcagatcga aacggctatg
    30661 gttatgaaaa tgaaattcgt tccgtattgc atgggtttaa attcgattct tcattttatg
    30721 atcagaaaat cgatacttta tcaggcggac agcgcacacg tttagcttta gctcgcatgc
    30781 ttttgcaaca ccctgacatt ttgattctag acgaaccaac gaaccattta gatatcgaga
    30841 cactttcctg gcttgagaat tatctgcaaa gctatactgg tgcattattg attgtttccc
    30901 atgaccgtta ttttttagat aaagtagtca atgaagtcta tgaattaagc agaagaaaaa
    30961 tgcgccatta caaaggtaac tattcgaaat atctagattt gaaagcagaa cagttagcaa
    31021 gtgaatggaa ggcttatgaa aagcagcaaa cagaaatcca taaattagaa gacttcgttg
    31081 ctcggaacct tgttcgcgcc tctaccacaa aacgagcgca aagccgcaga aagacattag
    31141 aaaaaatgga ccggctggat cgtcctcaag gggatgaaaa acaagcaaac tttctattca
    31201 gtatagaaaa gccttctgga aatgtagtct tgcaaatcga agatgccgct atcggatatg
    31261 ataatgtcac cttatctgaa ccaatcaatc tagatatccg tcgtcaagaa gcgattgctc
    31321 tagtaggtcc gaatggtatc gggaaatcga cgttgctgaa atcaatcatt caccagatcc
    31381 cttttatccg tggaaaagaa acgctaggga caaatgtcac catcggctat tacgatcaag
    31441 gtcaagctga tctgcataca aacaagacga tcctagcaga attgtgggat gagcatccta
    31501 ccactccaga aaaagagatc cgaagtgctt taggtgcttt cttattttct ggcgaagatg
    31561 tagaaaaacc aatccctctg ctaagtggcg gtgaaaaagc acgggttgct ttagccaagt
    31621 tagcgatgaa caaagaaaat tttttgattt tggatgaacc aacaaaccat ttagatattg
    31681 acaacaaaga agtattagaa aatgcattga tcgattatga cggcacactg ctttttgttt
    31741 cccatgaccg atatttcatc aatcggatcg cgacaaaagt cgtcgaactc tctgaaaatg
    31801 gcagcaaagt ctatctagga gactatgatt attatttaga gaaaaagcag gaagaagaag
    31861 aaatcgccga attgttggca caagatgagc cagaatctgc tcctgctccc acgaacaaat
    31921 ctgattatta ccaaagcaaa gaacagcaaa agcttatccg tagccttcaa cgaaaaatta
    31981 ctcaggttga agaagaaatg gcgcggatcg atgaatggat cgatcagttg gaacaagaaa
    32041 tggtcgcgcc agaaaacctg gaagatcacg taaaactcaa tgagctgaac caagatttag
    32101 aagctgctag acaagatcaa gaaacaaaat tgacggaatg ggaagaacta agcttggaat
    32161 tagaagaata tgaaaattaa cgaaaaaacc aaaacagaaa ccattcatgc tgttttggtt
    32221 tttctttttt tattttatca aacaaaaatt ccatatttac ctttttcacc aataagaaga
    32281 ccaattacta gtcattctca ctaaagcttc taaataatag taatcacccc aaatacaagg
    32341 tgtatttacc ccattatttt tgggcttatt ataaacagac tgtgttaaaa agccatcttc
    32401 ttcttccgtt gtagcatatc tttctttcaa ttgtcgcata attttccaaa cagcagactg
    32461 gtataagttc ttttctgttt tgtctaatag acctgattct attaattcta ataatccaca
    32521 aaccatgatc accatactag atgtatcttt ttcttctctg ctagaatcat caaagatcaa
    32581 atcccaataa caaatggtat cttctggcaa ccgattcata aaataattgg ctaatatttt
    32641 gcttaaatca aaatattttt gttctttcaa ataacgataa cttaatgcaa aaccgtaaat
    32701 cccccatgct tggcctctag cccaacagga attatcacta taaccttgat gcgtacttcc
    32761 atatcttggt tttccatctt tgacatccat ataaaatgta tgataagttg aaccatcttc
    32821 tcttactaaa taatctgctg cattttgaat atgagcctga gcagcttttt tatatttttg
    32881 atttccagtt tcttcactcg cccaatacaa taatggaaga ttcatgcaac aatccatgat
    32941 cattctacct tgttgtgaag gatcactagg atctccccaa gcttgtataa ctcctgcctt
    33001 ctcccaaaaa cgctgaagta atgtttctgc agcatcaatt gaagcttcct tcatttttcg
    33061 atttcccgtt attttataat ctgctacggt tgataaagaa tacaaaaaac caagatcgtg
    33121 atgattagtg ataatttgac agtcaatcct gtggataaaa tctatatctg ctttttcagc
    33181 tgtttgttga aataaaggat cacccgtctt ctcaaataac aaccaattaa ttcctgtcca
    33241 aaatccttct gtccaaccaa tattgtctct taatggataa cgtcctttta taggacactc
    33301 gcttgggaat tgatactgac tgttactgat acgtttgatt aacctctccg tgtgtctgcg
    33361 acaacgctcg atctcattat tccattcttt ttccattaat tctttataac attcatttat
    33421 ccatttttct ggatgtatta tctcttcaaa catcacttta tcaagcattt ccccaccagc
    33481 ctttagcata attttagtct ttttttattg tttttatttt ggatagttag cccggttgtc
    33541 ccatcaaaat caattttggg acgattgttc catacttcta aactataatc ccgatcttga
    33601 tgagcaacca ctcctgttcc gagccaatgg gttccttttc caaatgtacc ctctaatcca
    33661 ggaataaaag tgttttccca tgtcatcaag tttgtattgg gcaaacccat aatagctgtg
    33721 gattttcgtt taatagtatc gtcacttaaa cagataatac ctgaaaagcc agcttcactc
    33781 accctatagt tttccttgtc ttcttctatg attattcctt ctttctcagg agaacattca
    33841 atagcaaacc ctgtctcata tagaacatat tctgtatcta attctacttt gtgtacgcga
    33901 atctgccagc cttcaaaagg aataagccaa gttctgattt ttgcctgtaa agtaggttcc
    33961 catgtagagg caagtacctc tttcttacat acaatgtctc gtacattatt tcgaacgatg
    34021 aactgtccat aggttttgat gctctcattc ttaaaactgg tcgtgatata tgtgtccgct
    34081 cgctgaatcc ctagcattga atccattgcc atttctgctt tcaattgatt cgctcgcggt
    34141 atcgaaaaac caaattgact agaataagca aattttaaat atttttcatt ggtcaatgta
    34201 tggaaatttg gccctaattg tcccgcattc aaaaaaaatg tatgtccatt atcatgttgt
    34261 atgagcaaat tggcttctga aagaagttta gttccttcac gaataggcat aggcatttct
    34321 ttagccgtcc aatactcatg gtcttcaggt agcgccaaca ataaaaaaat cttattcagc
    34381 cataatggag ataacgtact attatagggt tcagtcaatg tcaattgagg gtaggtataa
    34441 ccaatattca ggataccttt ttcatcaaat atttcttttt gcatccacca tcttatattc
    34501 cgattgacta accccttgat ttcacctaat ttaaaaggca aaagatcggc ccacaacata
    34561 gctgaccaaa agcttgaaac tgcaaaacga taaatcatgc ttcgaccaaa aggcacattt
    34621 gcaccatctt ccgcaaaaaa atgaatatag tctctagaaa aatcaatagc tcggttctta
    34681 tatatctggc taatgggctt ttctggttct agtacgctat aaatcaaacc ataataatga
    34741 aatgcaaaag gattataata atcttggcga cctcttgaac tgtctcgata ccagccattt
    34801 tgaagataac aattttctat attatcaaat gcttctttca gtgctgattc tttaactgga
    34861 taaccaaatt tttggataat tgttccgaca attatcttaa aaaattgcca attaccatct
    34921 gcacattcat attcaaaaat ttgcgagaac caatgaataa tctggctttt ttctcctgta
    34981 tctaattttt tccataataa ttgttcatga tgatataacg ctaataacat tgcgggcatt
    35041 tctaccatac gctggtctct ttcatgtatt tctccccaat aatcgggatg ggaaggatct
    35101 gttccagctt ttattcctga tagaattaat ttcaaccatc gttcatctaa ttggtcaatt
    35161 gcgggccccg ctccccataa aacccgagag aatccttcca ttcctgcaat tttatttcca
    35221 tatcctaccc cttgatgtat ataatcaatt tgtgcgccac ttgctcgata aaacggctgg
    35281 agtggttgat ttatcttttt aaataagtca aagtaatcct gtctggtcct taatagtggt
    35341 actggatgtt tcattgtatt ttctcctctt tttactacca aatagctaat tccgactgtt
    35401 ctaatcgaag taagccttca ataaaaaaat aatcagaata gatcagtggc acattataag
    35461 tcagttctct atggtatgct tctgctccgc ctccaatgat cccatcttca tccatattcc
    35521 aatttgcata gtgcttttct gtcttttgga gtatattgat agcagcttca tgatacattt
    35581 ttgatcgtac agaggaaaca tatcctgcta attccagaag accgcatgca gcgcatactc
    35641 cagcactggt atcaatattc gaatctttta cagcaaaatc aatgagagga atataaccag
    35701 ttttttcgat tttctgaata aaatttactg ctatcttttc tgctatagct agatagtacg
    35761 gattttttgt gtaacgataa cttaacgcga atccatataa agcccatgca tttcctctgc
    35821 tccaacaaga attctcattg tatccttgcc cgccaagtaa ccgaatatat ttccctgatt
    35881 ctgcatcaaa ttctgcgata tgcccggttg atccatcttt cctcactaga tacttagctg
    35941 ttgtatctgc atgctgccga gcaattttag agaacctcgg atcaccagtt tccctcgaag
    36001 cccaatacag taatggtaaa ttcatcatac tatcaataat catccaacca ggtttatggt
    36061 cattccatgc tactaaatag ttccctgaaa tattatagcg tccagcaagt accgtagctg
    36121 catgtaaccc tagttgtcga ctatgtttgt tttgagactg ttgataatgt gcaatagccg
    36181 atggtaagaa taaaaaacct acatcatgat gaacgtctga aaaatggtac agggcagatt
    36241 ctaataattg ttcttgttgt attgctgcct ctttgaactt ttctcgtttt gtcttgtgaa
    36301 agagctgcca taaaatacca ctccaaaaac cattggtcca ccagtcgatt cctctgtcct
    36361 ttattacgtc tgtatatttt ccgttgtaag aaatatatgg aattttattc cccattctgt
    36421 ctaattccgc atctatcttt tcagaagcta cattcaaaat ttttcttgac cattccttcg
    36481 tctgttcatt catggatatc ccgccattct tttaattttt atgaatgtgg agttgctcct
    36541 agaacgaact agatggttaa cattcgttat tttttttact tatttgcagc tccaatgtca
    36601 ttctccttaa atttagactg cgcccacaca taaatcaaga ccattgggat cactgaagtt
    36661 gctaaaatta gcataattgc gccataatta attggctcac ctgtactaga aaccgtcata
    36721 tttttgataa ttaagggaac cgtatattta tctttatctg aaagcatgac taatggaaat
    36781 agatattgat tccaacttcc cataaagata agtaaaccac tagtaataat cgtaggtgat
    36841 aaaatcggta cagcgatttt cgtaaaaatc acccactcat tggcaccatc gattctggca
    36901 gcctccatca gtgctgtagg aaattgactg ctatattgtc gcatcataaa cactgaagtt
    36961 gtactggcaa tcgaagggat gatcacacct gcataagtat tcgataatcc taaacgactc
    37021 ataatgtaaa ataaaggaat caatgtggta aaaaaaggca ccatcctaga tagcataact
    37081 gtattgaaca acagtttatt ccccataaaa cgatactttg ctaatgcata acccgccatt
    37141 gtagaactgg ctgtagctga aactgtactg attacagcaa taacaatcga attccaaata
    37201 atcaagggat aattatatct cgccatgatg gcttgccagt tttttaatag catatcccca
    37261 aacttgaaat tgattccgcc acttaaaatt tcttgattac tttgcgttga agctacaatc
    37321 atatataaat atggcatcaa aaatattaag gcaccaaaca caataatgac gtacgtaaaa
    37381 attctgcttt gtatcttttg tttagtcatt tttatcacct ccgaatttaa attgaatagc
    37441 cgataatata acagatacaa acaccatcgt ccaggcaata gcagaggctt ttccaaaatc
    37501 aaccatttca aaacttgttt tatataaatt gactcctacg accaaagctg aattttctgg
    37561 tccattggaa gtcccaaaga atatatttgg gatattgaaa ttacccaagc cattgatagt
    37621 ggctaaaact gtggccatta aaatgattgg ctttagcatg gggatcgtta ataaaaagaa
    37681 ttgccgaaat ttcgatgctc catctatttc agcactttcg tatatctctt tagaaatccc
    37741 ttgaagacca gctaaaaata aaatagtgtt atatcctaca ctaagccaaa tcatcgtgat
    37801 gatcattgat attcgtatcc aaaaaggatt tgttaaccac tgtacaccgt taattcctag
    37861 cgcattcaaa aatccattga ataacccagt cggattgaaa aaagtcatga atacggaagc
    37921 tacagccacc gttgatgtaa tggttggaat ataatagaca gttctaaaaa atccttttcc
    37981 ttttaactgt gctgaattca ataaaacagc aaagtaaata gctaatagca tcgttattgg
    38041 aattgatcct gccatgataa tcaaaacatt cgtgtaagat ttaataaaca atggatctcg
    38101 gaagatagct agataattgt caaatccaac aaattcaaat gagtagccaa ttttcataaa
    38161 actaaaagca aacgagataa tgatgggaat caaaatcgtc acaataaaga aaataacaaa
    38221 aggtgtgacc aatccataag cacttttttt atgagacgta tctgttgctt ttttcttgct
    38281 gttctttatt gtcttgcttg gtaacgaaga ttgcatcatc gttaagtcct cctaatattt
    38341 tttaatcacc agttaatttt acgccgtact tatgagcaaa attttctgct tcttttagat
    38401 atgaattttc aaaatcacct gtttgccaat agttatatgc agcggtagtc aaataagacg
    38461 tagcatctga ataagtggct ggtaaaacag tatttgatgt attttcattg attttattca
    38521 atagttcata gtatttttgt cctccttagt agtcaaactt tttctcagct gcttctgttt
    38581 gataggccaa tgagttagat gtagccacgc ccagctccag tgcgttggct aagcattctt
    38641 catctgtcag cataaatgta agaaattgtt gtgccacttg tggatttttg gcatctttag
    38701 ggacataaaa acttgatcct cctgatactg caccttttcc tggattttct tttgaaaaag
    38761 gaatcagtgg agccatgcgc catttgtcag atgcatcagg aaaattcaaa gacatattcg
    38821 tagcatacca gccgccagca acaaacattg cagattcttg aaatgctttc tcagcatctt
    38881 gtgcaccgta gaaatgtaca atatctgagt cgatcatttc tttgattaac tttgcagcat
    38941 gtttcgcttc tttagtattc agacggatat ttccttcttc atcaagcaaa gattgattct
    39001 gctgggctag catgttgata aacaattctt ggtccccaga ttctggcaag gcaattccaa
    39061 aactaccagt tttttctttt aatgcttttg ccacctggat atattcttcc caagaactga
    39121 tttcttcaaa atctacacct atttcagcaa atttttttgg ttgataataa caaagtgctg
    39181 gggtaaaatc actagcccaa ggaataatcg tttcattact cgtttgttga cgcaaaatat
    39241 tcaatttttg atcataaaac tgatcgccat atttgtcata aaatccatat tcatcagcac
    39301 tataaaaagc atcttgaaat ttttccagca cacctgctgc tgaagtgtct gccatggaga
    39361 taatatccgg catatcttcg tgtgttacca attttggggt gatcatttgt actgttgctg
    39421 ttcccgaagc tacattcaca atttttaagt caatatttgc tccagttttg cggttataga
    39481 tttttgcagc attttcaaca tagtttgtca gtttgccgtt tgcgacatat acttctaatg
    39541 tagtggcttt ttttatcatt ggatctgcga tgtttgctgt tacttcttcg ttagtttttc
    39601 cacatgcact taagctgaat aatagggtaa tgtttagcaa agctatcacc aatttgtatc
    39661 tttttttcat gtctatccct tctttctttt caagttctta tataaaacgc tttcacttat
    39721 gtatattaac ggaattagta acacaaatat ttatataaaa aaatatttta cttgtcgttt
    39781 tggcttttca tttttgttat aatagtcatt aattataaat agaaagcttt ttatataaaa
    39841 agagaaagga aagtggttct tttgttaaca aacaaccaat cctccaatct tgtcaaaaaa
    39901 acactaacct attccataga tacccatctt catttatctg ctgctcccta ttttcgacta
    39961 ctaataaatg aaagcgctaa tttatatgct gaatttgcac ataaatctat agaactagat
    40021 aatccttccc ttttattcat tgataaacag caagaagtcc aaatcttttc tactcaaaag
    40081 gaaacacaaa cttttatcat tatccagttt tattttgatg agcaattatt agcacatatt
    40141 acgggacaat ctttttctat agatcaagaa ataacatcta tcattacttt tctgaaaaat
    40201 gaacagttca aaattgatta tctaaaacat agtaagccag ctatttccta tgatcaggaa
    40261 atcaattctt ttttcatact atgccaacag atgagcattc atttgctttc cttattagtt
    40321 acttattgtc tgcaaaaaat tcaattgtct tccttaccaa ggcattatca acaggaactt
    40381 gctttattga caataccttc aaatgagaaa gtcattccta aaaaaaagca tattctttat
    40441 tcagatgaat tagttgatcc aatcatacga tatttagaag aacatctttc agaaaatttt
    40501 ttgcttgaac aattagccca aatttttttt atcagtccag ccagcttaaa aaaacatttt
    40561 agaaaagtga atggaaaaag tgttattagc tattttaaag aactaaaaat ggaaaaagca
    40621 aaacgtctcg tgctagaaaa tgaattaacc tatacagaaa ttgcagatat attaggattt
    40681 cattcgatcc atcatttttc ttcagctttt aaaaaatata cagggttatc cccttcaaag
    40741 tattatctat ccttaaaata gaaaaaaatt tttaggtttt atccacaaat tatttctcta
    40801 tattttctgt ctattcaaaa taaacaataa ttttccggca caattatttg ctgtttttta
    40861 ccataacata gtacgatcaa cgtagaaaag gagatgtttt tatgaaagtt gttgtcattg
    40921 gcggtgtagc tggcggtcct tcatttgcca ctcgtttccg tcgattgaat gaagcgcacg
    40981 aaatcattat ctatgaacgc ggagaaaata tttcttatgc aagttgtgct ttgccttatt
    41041 atttaggagg tgtgatcact gaccgtgact cgctgatcga acgtacacca gaaatattga
    41101 aaacaaaaaa caacatcgat gtctttacta aacacgaagt aacagcaatc gatccttcta
    41161 ctaagcgatt aacagttaaa gacctatcca caaatgaaga aataaaaaca gattacgata
    41221 agttgatcat ctcttctggt gctagaccag attatccgga tattcccgga gtttttgaag
    41281 cagaaaacgg ctttgtcctc cgtagtgtga cggatgcgga tcgaatcaaa tcgttccttg
    41341 aagaaaaaaa tccacaacat gtcgtcattc ttggtgcagg tgttatgggt ctggaattag
    41401 ctgagaattt caagcatcgc ggcttagacg tgactttaat cgatcaattg ccacaagtcg
    41461 ctttccctta tgatccagaa attgctaatt tagtttatga caaattgctg aaagaaggat
    41521 tagccgttca tttagaaaca agagttactg agatccgtga taaaggtcga gaaatagtat
    41581 tatcagatgg ctccgtcctt tctgctgata tgctaatttt tgctgttggt gtttctccga
    41641 agaatgaagt ggtgaaagca accggcatac aattatcaga tacaggtcag atcattgttg
    41701 atgaccagtt acaaaccaat ctgccggaca tctatgcgat tggcgatatt atcgaaacga
    41761 ctagtgtagt gactggtcag ccgatccaaa gtatgctttc cagtgcggcc aatcgtcaag
    41821 gacatatgct ggcagatatt ttaaatggta cgcctatgcg ctatcgcgga tatattggtg
    41881 caggtgtcgc aaaaatcttt gatcatacag caagttatgc gggaatgaca gaacatgaat
    41941 taaaagcatc aggcataaca aattataaaa ctgtttttat cactcccttt gaccatgcct
    42001 atttctatcc agaagctaca agattaaatc taaagctgat ttttgatgca gatagcggtc
    42061 gtattttagg tggacaagca tttggagaaa aaggtgtcga taaacggatg ggagaacttt
    42121 ctgtagcaat caccggaaac ttgacagtct ttgatttgcc tgatttggag ttgccttact
    42181 ctccaccgta ttctactacc cgtgacccgt tgaatatagc tggttatgtc gcaatcaatc
    42241 aaatgacgaa tatcgtagaa acgatcaaag caagtgatat acccgaaaac gatttgaaag
    42301 aagcgttctt tttagatata cgtgaaccta ataaagcacc ttctggcagt atctcggcaa
    42361 caaaaaatat tccaatgaat gagttacgag atcgaatcaa tgaaatccca aaagataaaa
    42421 aagtttacat tactttcaga agaggattga ataattatac ttctgcccga atcttggcag
    42481 gtttgggtat caaagcgatt ttgattgaag aataaaaaaa cgaccgcggt gggtagccgc
    42541 ggtctaggag ttatttttac ttgaggagta aaaatgaaaa agtatatagg gttgttggtt
    42601 ggtatgtata tagaatagaa gataaatgtg aagaaattgt gcattatttc ttcacattta
    42661 ttaggttata gtttaagaaa gtttaaacat tgcgcaattt aattatttta gctgtttctt
    42721 ttcataaaaa aacatgttgt gactctgaga caaatcatag tccatagtga tgtctctaga
    42781 gtaactacgc ctaatattac gaggcatcat attaatctat cagcactagt acctaaacta
    42841 gcatcccttt cgaatatttt ttcttatata ataaagtttg ctttcactcc tctaatctca
    42901 ccaaatcgac tggcttgcgt tgtgtgatac taggaactga ttggtttaga acgacttttc
    42961 tattgtaatc atatttttcg ccatcctcgt tgtcttctaa tccttcaatg aatgatccct
    43021 aatgtgtgta ttaaataatt taattttttt gttcctattt atttaaca
//
LOCUS       DACGLI010000023        42464 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.024, whole genome shotgun sequence.
ACCESSION   DACGLI010000023 DACGLI010000000
VERSION     DACGLI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.024"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..610
                     /locus_tag="IXT22_001288"
     CDS             <1..610
                     /locus_tag="IXT22_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4862667.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="IXT22_001289"
     CDS             723..1001
                     /locus_tag="IXT22_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4862668.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="IXT22_001290"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="IXT22_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAQ4862669.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1467..2213
                     /locus_tag="IXT22_001291"
     CDS             1467..2213
                     /locus_tag="IXT22_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4862670.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="IXT22_001292"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="IXT22_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAQ4862671.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="IXT22_001293"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="IXT22_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAQ4862672.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="IXT22_001294"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="IXT22_001294"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAQ4862673.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="IXT22_001295"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="IXT22_001295"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAQ4862674.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="IXT22_001296"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="IXT22_001296"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAQ4862675.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="IXT22_001297"
     CDS             6950..7492
                     /locus_tag="IXT22_001297"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAQ4862676.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /locus_tag="IXT22_001298"
     CDS             7515..9071
                     /locus_tag="IXT22_001298"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAQ4862677.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="IXT22_001299"
     CDS             9085..9987
                     /locus_tag="IXT22_001299"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAQ4862678.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="IXT22_001300"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="IXT22_001300"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAQ4862679.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="IXT22_001301"
     CDS             11430..11852
                     /locus_tag="IXT22_001301"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAQ4862680.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            12321..12551
                     /locus_tag="IXT22_001302"
     CDS             12321..12551
                     /locus_tag="IXT22_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAQ4862681.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            12648..13949
                     /gene="murA"
                     /locus_tag="IXT22_001303"
     CDS             12648..13949
                     /gene="murA"
                     /locus_tag="IXT22_001303"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4862682.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            13962..14138
                     /locus_tag="IXT22_001304"
     CDS             13962..14138
                     /locus_tag="IXT22_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4862683.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            14273..14569
                     /gene="yidD"
                     /locus_tag="IXT22_001305"
     CDS             14273..14569
                     /gene="yidD"
                     /locus_tag="IXT22_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAQ4862684.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            14754..15221
                     /locus_tag="IXT22_001306"
     CDS             14754..15221
                     /locus_tag="IXT22_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862685.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            15306..16190
                     /locus_tag="IXT22_001307"
     CDS             15306..16190
                     /locus_tag="IXT22_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4862686.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            16307..16540
                     /locus_tag="IXT22_001308"
     CDS             16307..16540
                     /locus_tag="IXT22_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAQ4862687.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            16628..16708
                     /locus_tag="IXT22_001309"
     tRNA            16628..16708
                     /locus_tag="IXT22_001309"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16662..16664,aa:Tyr,seq:gta)
     gene            16715..16786
                     /locus_tag="IXT22_001310"
     tRNA            16715..16786
                     /locus_tag="IXT22_001310"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16747..16749,aa:Gln,seq:ttg)
     gene            17301..18008
                     /locus_tag="IXT22_001311"
     CDS             17301..18008
                     /locus_tag="IXT22_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4862688.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(18067..18711)
                     /locus_tag="IXT22_001312"
     CDS             complement(18067..18711)
                     /locus_tag="IXT22_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAQ4862689.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            18837..19124
                     /locus_tag="IXT22_001313"
     CDS             18837..19124
                     /locus_tag="IXT22_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862690.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            19232..19552
                     /locus_tag="IXT22_001314"
     CDS             19232..19552
                     /locus_tag="IXT22_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4862691.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            19633..20946
                     /locus_tag="IXT22_001315"
     CDS             19633..20946
                     /locus_tag="IXT22_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4862692.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            20943..21662
                     /locus_tag="IXT22_001316"
     CDS             20943..21662
                     /locus_tag="IXT22_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAQ4862693.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            21790..22341
                     /gene="raiA"
                     /locus_tag="IXT22_001317"
     CDS             21790..22341
                     /gene="raiA"
                     /locus_tag="IXT22_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAQ4862694.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            22563..25097
                     /gene="secA"
                     /locus_tag="IXT22_001318"
     CDS             22563..25097
                     /gene="secA"
                     /locus_tag="IXT22_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAQ4862695.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            25223..26324
                     /gene="prfB"
                     /locus_tag="IXT22_001319"
     CDS             join(25223..25285,25287..26324)
                     /gene="prfB"
                     /locus_tag="IXT22_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAQ4862696.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            26429..27115
                     /gene="ftsE"
                     /locus_tag="IXT22_001320"
     CDS             26429..27115
                     /gene="ftsE"
                     /locus_tag="IXT22_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAQ4862697.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            27099..27992
                     /locus_tag="IXT22_001321"
     CDS             27099..27992
                     /locus_tag="IXT22_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862698.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            28144..29592
                     /gene="cls"
                     /locus_tag="IXT22_001322"
     CDS             28144..29592
                     /gene="cls"
                     /locus_tag="IXT22_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4862699.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            29929..30786
                     /locus_tag="IXT22_001323"
     CDS             29929..30786
                     /locus_tag="IXT22_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAQ4862700.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            30901..31821
                     /gene="pstC"
                     /locus_tag="IXT22_001324"
     CDS             30901..31821
                     /gene="pstC"
                     /locus_tag="IXT22_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAQ4862701.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTITTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            31821..32705
                     /gene="pstA"
                     /locus_tag="IXT22_001325"
     CDS             31821..32705
                     /gene="pstA"
                     /locus_tag="IXT22_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAQ4862702.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            32720..33526
                     /gene="pstB"
                     /locus_tag="IXT22_001326"
     CDS             32720..33526
                     /gene="pstB"
                     /locus_tag="IXT22_001326"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862703.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            33542..34300
                     /locus_tag="IXT22_001327"
     CDS             33542..34300
                     /locus_tag="IXT22_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862704.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            34313..34990
                     /gene="phoU"
                     /locus_tag="IXT22_001328"
     CDS             34313..34990
                     /gene="phoU"
                     /locus_tag="IXT22_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAQ4862705.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            35228..36259
                     /locus_tag="IXT22_001329"
     CDS             35228..36259
                     /locus_tag="IXT22_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4862706.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            36256..37023
                     /locus_tag="IXT22_001330"
     CDS             36256..37023
                     /locus_tag="IXT22_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4862707.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            37123..38691
                     /gene="liaX"
                     /locus_tag="IXT22_001331"
     CDS             37123..38691
                     /gene="liaX"
                     /locus_tag="IXT22_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAQ4862708.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            38991..39308
                     /locus_tag="IXT22_001332"
     CDS             38991..39308
                     /locus_tag="IXT22_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAQ4862709.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            39308..39658
                     /locus_tag="IXT22_001333"
     CDS             39308..39658
                     /locus_tag="IXT22_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4862710.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            39825..40763
                     /locus_tag="IXT22_001334"
     CDS             39825..40763
                     /locus_tag="IXT22_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAQ4862711.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANKNGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            40778..41608
                     /locus_tag="IXT22_001335"
     CDS             40778..41608
                     /locus_tag="IXT22_001335"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAQ4862712.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            41652..>42464
                     /locus_tag="IXT22_001336"
     CDS             41652..>42464
                     /locus_tag="IXT22_001336"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4862713.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPL"
BASE COUNT        13978 a         7316 c         9263 g        11907 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagaa gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcgctaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttatttggaa taagggactg cgacaagact tttgtctcag tccctttttt
    12181 tgcatatttt tagcatttat ttcctaaaaa atgtaagggg attcctatat ttttaagtat
    12241 acttgttttt ccttttatac attttatggt attatcattt tattagttat tataaaacaa
    12301 tcgttagaaa ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga
    12361 gtcatttggc gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt
    12421 ttttcagacc aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt
    12481 tagggtacac tgcaagtaat tttttcttag aagttatcgc tttatgccga aatcttttcg
    12541 ttagcctgta aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa
    12601 gattttgagt aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca
    12661 tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg
    12721 ttttgcctat tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg
    12781 ttccgattct ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg
    12841 tagattttga tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg
    12901 aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac
    12961 ttgccagaaa tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac
    13021 caatcgattt gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg
    13081 gctatatcga agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta
    13141 gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca
    13201 ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg
    13261 gcgctcaagt ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac
    13321 atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg
    13381 ctgcaatgac acaaggcaat gtgctgattg cagatgctat ctctgaacat aaccgcccat
    13441 tgatttctaa attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg
    13501 tcatcggacc aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc
    13561 ctacagatat gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtag
    13621 tgactgaaac agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg
    13681 ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg
    13741 cagaagtata tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag
    13801 caaatggaat cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc
    13861 atatcaaact acagcaatta ggtgcagacg ttgaacgtgt agacatggat caaacttctg
    13921 ctgaaaaaac agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata
    13981 tcttattaac tttgataaag attttaatgg tgatcttatt gcttatcctt ctttttgtgg
    14041 ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtatttcagc
    14101 caagtttgtg gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc
    14161 tagtcgatat gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt
    14221 gacgttagtc gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa
    14281 gatattgatt tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag
    14341 ctgccgttat tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggcgc
    14401 gctaaaaggg acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg
    14461 cggtatcgat tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga
    14521 accagattat aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaacaattt
    14581 ggaaaatagc ttcttatatt ttgcaaaatt gtgagttatt gccgaagtgt tggattttga
    14641 acaccgtcaa aaaaaaggtt gtgaaaaata cggctagcac tgagcgataa agaaaaagag
    14701 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    14761 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    14821 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    14881 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    14941 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    15001 agctttcaca actcgcttcc agtcaaactc agatcatcat acgaaccggc agtactagca
    15061 gtgcggcgtt acatctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    15121 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    15181 tgattttagc aattcactta cctaaaaata gctttaacta ataaaatttc aattcaagaa
    15241 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    15301 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    15361 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    15421 aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    15481 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    15541 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caacttccag
    15601 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    15661 gcgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    15721 cgaaaggaca aatcaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    15781 taaatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    15841 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    15901 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    15961 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    16021 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    16081 tcgatctgca tgatttcgaa ccgcagattt tattatgtga atacagaaac gatgctaatc
    16141 ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg ggagaattaa gagctttaga
    16201 gaaggtgcag cttgcataaa agaagtgaat gaaatgaata ggagattttt acctaaggaa
    16261 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    16321 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    16381 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atggaccaaa
    16441 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    16501 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    16561 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    16621 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    16681 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    16741 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    16801 aagctctcgt tagttcgaga gctctttttt ttgctttgct accttgttcc ttgaagattc
    16861 tgctgattta agatagagtt aagttaacta caagaattgg agggatccac atgaaatgga
    16921 aagaaaaagt agacgaagca gctgaaaagt tatatgattt ggtcaaatca gaaaaataca
    16981 atattgaagt gaatattccg aaaaaaggcg gaaaagcggt ccgggtaaaa tcaaaacgcc
    17041 caacgaatca tacaaaaaaa tggatggcta aaaaccgcta ataataacaa aagatccata
    17101 agtcggcatt ttcatcgatt ttagggtctt ttgttatttt ctaggttgga catatctaaa
    17161 aaattgtttc tgacaatagg agtaggaaga acgatgtgtg tctaaatcct ctgttgatgg
    17221 atagaaacct ttatcttttt cagttgtgaa tcaggtatat accagttata atagaagaaa
    17281 cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt atatatacag attcatgacc
    17341 aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg agaccgtctt ccttcagaaa
    17401 gagaattagc agtgaaattc aatgtcagcc gtatgacgtt gagacaagca attcaaaact
    17461 tggcagatga aggaatctta gaaagaaaga tcggttcggg tacatatgtt gcacgagaaa
    17521 aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga aattatggaa tcacaaaatc
    17581 gagtaccgtc tagtcggaca atctcttatt tcttgacttc gccaagctca agtgaaatgg
    17641 aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat ggaacgtatt cgtttcgcag
    17701 atgatgtccc tatttgtttt gaagttgcca gtgtgccaca aaagctgatc gatggctaca
    17761 gcaaagcaga gattactgaa tcgttgtatc gcacgctaga agaaaaaggc gggaaaaaga
    17821 tcggtccagc gaatcaaacg attactgctg tgttggcttc tgagaaaatt gctgactatt
    17881 tagaggtaaa acgaggagat gcagttcttc gtttgcgcca gatttcttat tttgaagacg
    17941 gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa tcgttttgag ttttatttgg
    18001 aaaaataaaa aacaggtgat ccctgattcc gtattagaaa taaaagagaa tcagaatcac
    18061 ctgtttttat atatgatcag ttaccagttg ctcgtgataa gaaacaggac cctcttcaaa
    18121 ttggacttgt ccgttcagca gctcaatgat ggattcttta aagtggtcag cacttttttc
    18181 atctacagca cagatgacgc taacttgatc agtatattgg atttctttta taaaaaaatg
    18241 ttggagttca agataattct gtaattttcc tagttgcgga tacgtgatca tcacagagat
    18301 ctcctgttgc aaggtacctt ctacgattcc aatgtcagac aatgcttgag agaccgcatg
    18361 agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt cctccaaaat atcgagtgac
    18421 tactgcagct acattgatca gttgattttt tttgaggact tccaacatcg gtatgcccgc
    18481 cgttccactt ggttctccat catcgctgct tcgctggatt tcattttttt ctccaatgat
    18541 gaaggcgctg cagttatggt tcgctttcca atgttctttt tttatttctt gaatgaaact
    18601 ttttgcttcg tcctctgatt ctattcgtct aagagaacag ataaagcgtg attttttgat
    18661 ctcgatctca ctttgtccat tttcttttat tgtacgatag cgctcgatca tcttgtcacc
    18721 tcttttttca ttttctttat tcagtataaa taaagttcta ggttgtttca acactgtaac
    18781 ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag gcaggtggat ctggggatgc
    18841 aggaacgaat gaaaaagtac gatgcaatta cgcattattt gaagaacaat ggcggctctc
    18901 aagtaacgtt gacctttacc caatttgacg aactgctgtt tcccagtaac ggacttccca
    18961 aaacagcaag ggaaagtaca gattggtggg caaatgatta taaacaccct gaaaaaggtg
    19021 cctatggctg gataaatgca ggctatgaag tagttgtcat caatttggac aaagaatatg
    19081 tcgtgttcaa taaattagtg aaatctagtt ggctatttga ttaaataaac cgcgtttaga
    19141 aaacgttgac aaatttcttt ctttttatat aatagagtaa cagacgcgaa gaaaacgttt
    19201 gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa aaaacaatca tgcttgtatg
    19261 ttcggctggt atgagcacaa gtttactagt aacaaaaatg caaaaagctg ctgaagcaaa
    19321 aggaatcgac tctgatattt tcgctgtgtc cgcttctgac gcagataaca atcttgcaaa
    19381 taaagacgtg gatgtgttgt tattaggccc acaagttcgc tttatgaaag ctgattttga
    19441 gaaacgtctg gaaccaaaag gcattccttt agatgtcatc aatatggctg attatggtat
    19501 gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc ataggtgaat aaatagaaca
    19561 gtataactat cgaacaagcg atccaaaaaa tagatcgctt gttttttcgt atattttttt
    19621 agggcgaata atatgaatca tttttggggt agaaggcttc tgacgagaga tattaaagca
    19681 atagactgtg aggaggtaaa tttaccaaat tatgagaaga tcgcagcagt ggaacgtttg
    19741 agcaactgga ttctttgtca tcgctgtgga atgagaacgt ccgtcattga tggacagctt
    19801 gcagattacg gttatttttg tacacattgt ctatatttag ggcgatgcga cactcaacaa
    19861 gatttatatt tgtttgatca gcctgaagca aaacctcgag aagtcgtctt tttttggaca
    19921 ggacagctta ctgaaaaaca aacggaaatc tcaaagagaa tactttgcca ttcagaaaaa
    19981 agacatcatc ttatttgggc tgtaacaggt gcagggaaaa cagagatgct ttatcctatt
    20041 ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt gtacaccgcg agtcgatgtt
    20101 tgtaatgaat tgtttttacg ctatcgttat gtttttccag aagaaaaaat cacgttgctc
    20161 catgggaata cagcaacggc ttataccttt acttcttttg ttatctgtac gattcatcag
    20221 ctataccgtt tttatcggtc ctttgattta atagtgatcg atgagatcga tgcgtttcct
    20281 tataacgggg atgcaggatt agctcatgct gtgcaaacag cgattaaacc agacggacga
    20341 ttcatctact taagtgccac acctgataaa aagttactaa aggagatcaa gcagacgttt
    20401 gacatccaca aacttgcttt acgctttcat cggcgtttgc ttcctgaacc cgtcttggtt
    20461 ttcatgaata attggcgaca aaaatgcaag aacaagaaga agataaaatc tttggtgcgg
    20521 atcattcatc aattaattaa agaaaaccat atccttttat tttgtccaag tatcacgatg
    20581 atgcatcgtt tgaaagccac acttcaagag gctcttccga gatatgagat cacagatgtt
    20641 tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa tgcgagaagc aaaatatgac
    20701 atactgttaa ccacgatgat ccttgaacgt ggagtcacat ttgaaagaat atccgttatc
    20761 gttttaggag cggatcatcc ggtttttact aaatcttctt tggtacaaat cgcaggaaga
    20821 gccgatcgta aagggcctta tacgaacagt caagtatatt ttttctatga agaaaaaact
    20881 gcagctattc gaaaagcttg tcaggaaatc aaagaaatga atgaagaagg gaagaagata
    20941 ctgtgaggtg cagttgctgc agtaaagata tcgtccaaaa tttaacattc agcgagatta
    21001 ttggtgtttc gaaatacaga ttacctcaga cttgttcagt ttgtcgcgca caatttcatt
    21061 tattggaaac aagaggctgt tctggctgtc aaaaaccaat ccatttcaat ctagagagta
    21121 cgaaaaagaa agtaaattct atccccgttt actgcagtga ctgtcaagaa tggaagaaga
    21181 aatatccgac ctatgatttt cagcaccgtg ccttttttgt gtacgatgaa aatatgaagg
    21241 cctggctcaa tcaatacaag tttatgggag atatccgact agcaggcacc tttgcatata
    21301 aatggacgca gataaaaaaa gaatacccga catacatcta ttgtccaata cctttatctg
    21361 aaaaaaggcg aacagaaaga ggattcaatc aagtaagcga gatgttgaaa gcagcaagaa
    21421 ttccttttca gatgctactc aaaagagaga agcatctgct ggctcaagca aaaaacacgc
    21481 gaaaggaaag attggagatg cctcaacctt ttgaacttgc agtcaccttt tctaagatac
    21541 aaaataaaaa aatattgatt attgatgatg tctatacaac aggacagact cttttccacg
    21601 cagcagattg tttgcagatc gcacagccga aaatcatccg aactatttct ttggcgagat
    21661 gaattagatg tggaaatttg atagcgattt aatttgcaaa taacctagag ttcgatataa
    21721 tagaattaag aagagggaaa gagtggtcct tctccttctt gattgtggta gacgaaaggg
    21781 gtaattttta tgtttagata taatgtacgc ggcgaaaata tcgaagtaac tgaagcgatt
    21841 cgcgactacg ttgagaaaaa agtaggcaaa ctagaacgct atttcagtga cgcacccgat
    21901 gcaacggcgc atgtgaactt aaaagtttat acagaaaaaa cagcaaaagt ggaagtaacg
    21961 atcccattac cttatcttgt attacgtgcc gaagaaactt ctccagattt atacgcaagt
    22021 atcgatttgg ttgttgacaa attggaacgc caaatccgca aattcaaaac aaaaattaat
    22081 cgtaaatccc gtgaaacggg catgaatact gcaaatgctg ctgctttatt caatgaagag
    22141 gacgaaaacg aaaatgattc tgaattagat atcgtacgta cgaaacgcct ttcattgaaa
    22201 ccaatggata gtgaagaagc agtcttgcaa atgaacatgc tgggacataa cttctttatt
    22261 tttgaagatg cagaaacaaa tggtacaagt atcgtttacc gccgtaaaga tggaaaatac
    22321 ggactgattg aaacagactg atcagcctta cttaaataac aacgaaaact tgcagcagct
    22381 actgacagct gccgcaagtt tttttgagtt tcctcctctt ttagatgaaa tatgaataaa
    22441 ttatgaagtt cttactttaa tacgcttaag atatttcaat tatctataac taatgataaa
    22501 atgaaaagta aagtctacat agtctggata atacacagaa ggaaaaggag attacacaac
    22561 gcatggccaa tttgattcgt tcacttatcg aaaacgataa gaaagaacta aaacgtttag
    22621 atagcattgc aaaaaaagtt gaagcatacg ctgaccaaat ggcagcatta actgatgaac
    22681 aattacaggc aaaaactgct gaattcaagg gcagatacca aaaaggagaa acattagatc
    22741 aattacttcc ggaagctttt gcagtcgtcc gagaagcagc aaaacgtgta ttaggtttat
    22801 atccatacca cgtacaattg atgggtggaa tcgtgcttca cgatggaaat atccctgaaa
    22861 tgcgtactgg tgaaggtaaa accttgaccg caacgatgcc agtatatcta aatgctctga
    22921 ctggcgaagg ggtacacgta gttaccgtca atgaatattt agcaacccgt gactcgacgg
    22981 aaatgggcga actttataat ttcttaggat taacagtggg gttgaatatc aactcaaaat
    23041 cttcggatga aaaacgcgag gcttataatt gtgatatcac ttatagtacg aataatgaat
    23101 taggatttga ctacttgaga gacaatatgg tcgtttaccg ccatcaaatg gtacaacgtc
    23161 cgctgaatta tgccattgtc gatgaagttg actcaatctt gattgatgaa gcgagaacgc
    23221 cgctgatcat ttcagggcaa gcagaaaaat ccacagcttt atatacaaga gcagacaact
    23281 tcgtgaaacg tttgaaagaa gaagaagatt ataaaatcga tgtacaatca aaaacaatca
    23341 gtttaaccga agcagggatc gaaaaagcag aagaaacatt cggtttggat aacttatacg
    23401 acattgaaaa tactgcattg acccatcact tggatcaagc attgagagcc aactatatca
    23461 tgcttttaga tatcgattat gttgtccaag acggaaaagt actgattgtt gaccagttca
    23521 ctggtcggat catggatgga cgccgttatt cagatggact tcaccaagca atcgaagcta
    23581 aagaaggcgt agagatcgaa gacgaaacga aaaccatggc gacgatcact ttccagaact
    23641 atttccgtat gtacaagaaa cttgcgggaa tgactggtac agctaaaaca gaagaagaag
    23701 aattcagaga aatttataac atccaagtat accagattcc gacaaatcgt ccggttatcc
    23761 gtgatgatcg tccagatttg ctttacccaa cattacaaag caagttccac gctgtcgtgc
    23821 aagatatcaa agatcgctac cgcaaaggtc aacctgtgtt agtcggaact gttgcggttg
    23881 aaacatctga gttattatca gatatgctga atcaagaacg tattcctcat gaagtgctga
    23941 atgcgaaaaa tcactttaaa gaagcagaga tcatcatgaa tgctggtcaa aaaggtgctg
    24001 tgacgattgc taccaacatg gctggtcggg gaacagatat caagttagga cttggggtaa
    24061 gagaacttgg tggtctagca gttatcggga cagaacgaca tgaatctcgt cgtatcgata
    24121 accagcttcg aggacgtgca ggacgtcaag gagaccctgg tatgtcacag ttctacttgt
    24181 cattggaaga tgatttgatg aaacgattcg gttcagaacg aatcaaatct ttcttagatc
    24241 ggatgaagat cggtgaggaa gatgctgtta tccaaagcaa gatgctgacg aaacaagtag
    24301 aatctgcaca aaaacgtgta gaaggaaata actatgacac acgtaaaaac gtcttacaat
    24361 acgatgatgt gatgcgtgaa caacgtgaag taatctataa acagcgacaa gaagtaatca
    24421 tggaagaaaa aagcttatcc aagccactaa tgaacatggt caaacggaca atcagtcgtg
    24481 tagtagatgc gcatacacaa ttagagaaag aaaattggaa tttggaaagt atcatcgatt
    24541 ttgccggcag tactcttgtc catgaagata gtattactct tgcagatatc gaaggaaaaa
    24601 cagctcagga gatcaaagag tatctaaacg aacgagcaca agaagtattt aataccaaag
    24661 cggctcaact aaatggtcca gagcaactgt tggaatttga aaaagtcgtg atcttgcgtg
    24721 ttgtggactc taaatggaca gaccatattg atgcaatgga tcaattacgt cagtcaatcg
    24781 gcttacgtgc ttatggacag aacaatccat tagtcgaata tcaaacagaa ggctataaga
    24841 tgtttgaaga tatggtaggc gccatcgagt atgaagtcac tcgaatcttt atgaaagctg
    24901 agatccgtca aaacgtacag cgtgaacagg tttctcaagg aacagcttct cactcagaag
    24961 acggagatgc caaagaaaat agtaatacta gcgcgaaaaa acagccaatc catgtgaaca
    25021 aggtcggaag aaatgatcct tgtccttgtg gaagcgggaa aaaatataag aactgtcatg
    25081 gaaaaaatgc aaactaattt ctgacagcag gattggtgag acaaattctt tttttaagaa
    25141 ttcgtctcac cttctttctg ttatttgctg attctgttag actagatata atgaaaaaag
    25201 tatagtgaaa gaaggaaaaa acatggaaat atccgaaatt cgaaatctcc tgacagaaat
    25261 gcaggaaaag gtcacaagct tcaggaggtc tctttgactt agaccagctg gaagaagaca
    25321 ttgcggaagc agaagcaaaa atggctgaac ctggtttttg ggatgatagc gaagctgctc
    25381 aaaaagtgat cagtgaaaac aatgcaaata aagaaactta tgatcaattc cattctcttg
    25441 ctgaagaact ggaagaaatc gaattgatgg tggagatgtt gcaggaagaa cctgatgcag
    25501 ccatgcaaga agaagcagaa acacgtatca atgcgctaga tgaaaaaatg aagacatatg
    25561 aattatctat gttgttagat ggtccttatg atcgaaacaa cgccatcgtt gaattgcatc
    25621 caggggctgg cggaacggag tcccaagatt ggggcagtat gcttttacgt atgtatacac
    25681 gctgggcaga gcagcatggg tatcaagtag agacactaga ttatcaagca ggtgatgaag
    25741 caggaatcaa gagtgtgacc ctactgatca aaggacacaa cgcatttggt tatctgaaat
    25801 cagaaaaagg tgttcatcgc cttgtacgta tctcgccttt tgactcagcg aaacgacgtc
    25861 atacttcttt ttgttcggta gatgtgatgc cagagcttga tgaaacgatc gatatagaaa
    25921 tcaatccaga tgatttgaaa atcgatacgt accgagcaag tggtgcaggt ggtcagcaca
    25981 tcaataaaac agaatctgct gtacggatca ctcacttgcc tacaggaaca gtagtagcta
    26041 gtcaggcaca acgttcacaa ttgaaaaacc gtgagcaagc gatggggatg ttaaaagcta
    26101 agctttatca attagaagtg gaaaagaaag aacaagaagc agctgcactt cgaggagaac
    26161 aaaaagaaat cggctggggt tcacagatcc gttcttatgt tttccatcca tattctatgg
    26221 taaaagacca tcggacaaac gtagagacag gaaatgtcca agcagttatg gacggtgacc
    26281 ttgatttatt tattgacggc tatttaaaaa tgcatctaca ataagaaccc attgttaaat
    26341 tgaaataaaa ttgtaagatt ttgcaagcat gttgaaacat tgccatgcta taatagctaa
    26401 agactgaaaa agatatggag agaacgccat gattgaaatg aaggatgtaa tgaagaagta
    26461 ctcaaatggt acgaccgcta tccgcaatct ctcaattgtc atcgaacaag gagagtttgt
    26521 ctatgtggtt ggtccgtctg gagccggtaa atctacattc atcaaattga tgtatcgaga
    26581 agaaaaagct tcaaaaggaa ctttgaacgt cgcaggtcat gatctaatag caatcaaaaa
    26641 ccgcgaagtt ccttatctac gcagagaaat cggcgtggtg ttccaagact ataaattatt
    26701 accaagaaaa acagtatatg aaaatgttgc gtacgctatg caagttatcg gcagaaaacc
    26761 tcgggatatc aaaaaacgag taatggaagt gctggacctt gttggtttga aacacaaagt
    26821 tcgagtcttt cctagcgaat tatccggtgg ggaacagcaa cgtgtctcta ttgctcgggc
    26881 aatagtgaat acgcctaaag tacttatcgc ggatgaaccg acaggaaatc tggatccaga
    26941 aaactcatgg gaaatcatga aattattaga tcggatcaat gcccaaggaa ctactgtcgt
    27001 gatggctaca cataacagta cgatcgtaaa tacgattcgg caccgagtaa ttgctatcga
    27061 aaacggccgc attattcgag atcaagcgga aggggaatat ggatacgatg attagaacct
    27121 ttttccgcca tttattagaa agtatcaaga gtttgaaacg taacggctgg atgacagttg
    27181 cttcagtcag tgcggtaacg atcacattga ctttagtcgg tgtattcatg gcagttatca
    27241 tgaacgcaac taaattagct caagatatag aaggaaacgt tgatgtctct gtattcgtag
    27301 atatcggtac aaaagacgaa gagatgaaaa agctagaaaa agaattgaat gacttagatc
    27361 atgttaaaaa agttgaattt tcaagcaaag aacaggaatt gaaaaaaatc caaaacgaaa
    27421 tgggtgattc ctggaaattg tttgaaggtg acaataaccc gttatatgat gtgtatgtag
    27481 taagtgctac tgatccttct tatacaaaac aagtagcaga agaagcagca gatttgaaga
    27541 atgtttctcg ttctgattac ggtggagctt cctcagatcg gattttccaa atcgctggtg
    27601 cagttcggac atggggatta gttgcagcgg cattgctgct gttcgtagcg atgtttctca
    27661 tttcgaacac gattcggatc acgattttgt ctagacagcg tgaaattcaa atcatgcgtt
    27721 tagtcggtgc aaaaaatgga tatattcgct ggccgttttt ccttgaaggt ggctggatcg
    27781 gtctgatcgg tgcgattctt ccgattttga tcatcacatt tggttatgca tggtttttcc
    27841 aattgatcaa tccatcatta ttacgttccc attattcatt gattcatcca caaaatatcg
    27901 tttggaaaat caatctttta atggtcggca ttggtgtgat cattggttca cttggctcga
    27961 tcatttctat gagacgtttc ttgaaattct aataccacaa tataaataaa atgagaaagt
    28021 tggacagttt cgttccagct ttcttttttt attggctagg agaatagaag gaagcggctt
    28081 ttttcccttt actttaaaaa acaacttggg tattcttaag ttggtagaag aagaggtgaa
    28141 gccgtgaaaa ttatcgttga caattttttt acgatccttt tgattatgaa tattttgctt
    28201 tcctttatca tcgtttttcg agaaagaaag gaaactgctc aaacatgggc atgggtgctc
    28261 gttttgatgt tcattccagt tgtaggattt attttatata tttttttagg aagagggatt
    28321 tccaaagaga aaatctttga tttgaagatc caagggaaaa tcggtaagaa cctggaaatt
    28381 gaagaagaca aacaggcatt gatgcgaggg ctttatcctc atccgcctac tggacaagta
    28441 gatgtgaaac aattgatcta tatgctcacg gtatttgaaa gtacgctcta tacgactaaa
    28501 aatgaaatca ctttatttac agatggtcgt gaaaaattcg atgcgctgat tgaagatatc
    28561 aagcaggcag aagaccatat ccacttccag tattatattt atcgcagtga tgcattaggt
    28621 gaagaagttc gagatgcatt gacagaggcg gcaagacgag gggtaaaagt cagagtcctt
    28681 cttgatgcat ggggttccac acaagtttct tccagctttt ttcagaattt gaaaaaagca
    28741 ggcggagaag tcgcattttt ctttcctcta tttgttccgt atattaatcc tcggatcaat
    28801 tatcgcaatc atcgtaaaat cgtagttatt gatgggaaaa tcggatatac aggtgggttc
    28861 aatgttggaa atgaatatct aggattggta aagaaatttg gttattggcg agacaatcat
    28921 ttgcgtattt acggagaagc ggtgtatacc ttgcaaaacc gttttttgat ggactggaat
    28981 tctcagcata caaaagaagt aggctattct cccaaatttt ttccgtccat tcactctact
    29041 ggtgatatag ctgttcaaat cgtgacaagc ggaccagata ccgaacatga acaaatcaaa
    29101 atgacttatt tgaaaatgat ttcgttagcc aaacgggaga tattgatcca aacgccttat
    29161 tacataccgg atggatcgat tcatgaagca ctgaagttgg ctcttctttc aggcgtaaaa
    29221 gttcatatcc aaatacctaa caaaccagat catcttctcg tttactgggc aacgtattct
    29281 ttcgctgcag agctaatcga gtatggagca aggatcgaaa catatgagaa tggatttatt
    29341 catgcaaaga cgatgattat cgatggtggc attgtttcag ttggctcagc aaatatcgat
    29401 gttcgttcat ttcgcttgga ctttgaggtc aatacactgg tttatgatga acgaatggct
    29461 tcacgtgtaa gaaaagcttt ttttgaagac tcgaaaattt ctacgcatct cacaaaagaa
    29521 atgtatgaaa accgaggaat aatcatcaag atgaaagaag gattagcaag attgatttcg
    29581 ccgctccttt aaaacataaa aaggacatga gaaccatcaa cagatggaga tctcgtgtcc
    29641 ttttctaacg gggccatttc tgagagtacg tcagaaatgg agaaagcgtc tcgcatgagc
    29701 gaaattaact ttggggtatc tcttgttttt tggggaaagc aagaaataag ctaatatatg
    29761 ctattaaaag agacacattt caaagccagt atagcataga aacttttaat gagatagttt
    29821 tttttacaat tatgagaatt tattttgtta tttaatgatt ttgattcgtt ttcatcaagt
    29881 aatgaaaatg ataaaataaa catactttag gattaaagga gatttctaat gaaaaaactt
    29941 aaattattct taccaataat aggattagct attcttttat caggctgttc aaagtggatt
    30001 gatcgaggag aatccattac ggctgttggc tcttctgctt tacagccttt agtagaaaca
    30061 gttgctgaaa cttaccagac agaaaatcct ggaaaattca tcaatgtaca agggggcgga
    30121 agcggaactg gtttgtctca agtacagtca ggagcagtcg acatcggaaa ctctgatttg
    30181 tttgcggaag aaaaatcggg gatcgatgcc tcagcattag tcgatcatcg agtagcagtt
    30241 gttgggatca ctcctattgt gaacaaggat attggcgtaa aagacatcag tatggaaaac
    30301 ctgaaaaaac tatttacagg cgagatcaaa aactggagtg aagtcggtgg aaaagatcag
    30361 ccagtagtta tattgaaccg cgcttcagga agcggaaccc gtagcacgtt tgaaaaatgg
    30421 gtattggacg gagaaacagc tgttcaggca caagaacaag attcaagcgg aatggtgcgc
    30481 cagatcgttg ccgacacacc cggtgcaatc agctatgttg ctttttctta tgtttccgat
    30541 gatgtagata cgttgaatgt taacggtgta gaaccgacag atgaaaatgt gacaacgaac
    30601 aaatggacga tttgggcata tgagcatatg tacacaagag atcatccaaa aaaactgaca
    30661 aaagaatttt tagactatat cttatctgat gaagtacaag ataacatcgt tggagaacta
    30721 ggttatatcc ctgtttctca tatgaaagtc gaacgtgatt ggcaaggaaa tatcgttaaa
    30781 gagtaatctt tacacaaaat ttacaaactt agctaaactt ttacatgtta ttaaaaccaa
    30841 attgatgttc aatttgtaca ctgagtgagt atgttaaacc tgattaaggg ggagtcatct
    30901 gtggaagatg tgaaaaaagt attattaaca aaatcaaaac gttcaaaaat ggaacagcgt
    30961 ggaaaattca tcagtttttt atgtatcgcg ctgatcgtgt tggttgtatt atctattttt
    31021 tattttgtag ctagtaaagg attggccacc ttttttactg ataagatcaa tgtatttgat
    31081 tttctgtttg gtacagattg gaatccaagc caaatcggag caaatgggaa accaatggta
    31141 ggggcattgc ctatgatcac aggttcgttt attgtgacct ttttatctgc tatcgttgcc
    31201 acgccatttg ccattggtgc agcagtattc atgacggaga tctctcctaa aaacggaacg
    31261 aagatcttac agccggtcat cgagctgctt gtaggtattc cttctgtcgt ttatggtttt
    31321 atcggtttat cagttatcgt gccttttgtc agaagtattt ttggcgggac tgggtttggt
    31381 atcttagctg gtacatttgt gttgttcgtt atgatcttgc cgactatcac aacgatgact
    31441 gttgatgcat taaaggcagt gccacggcac tatcgggaag cttcattagc gcttggtgcc
    31501 acaagatggc aaacaatcta caaagtcgtg ctacgagcag ccgtgcccgg gattttaaca
    31561 gcagtcgttt ttggtatggc tcgtgcgttt ggtgaagcct tagctatcca aatggtcatc
    31621 ggtaatgcag cattgatgcc aacaggtctt actactcctg cttctacatt gacgtccatc
    31681 ttaacaatgg gaatcggaaa tacaatcatg ggaacagttg aaaataatgt gttatggtca
    31741 ttagcgctga tcttgctatt gatgtcatta ttctttaata tcgtgatccg tatgattggg
    31801 aagaaaggag agctgaaata atgaacgcaa aacgctcaga taaaattgct acaggtgttt
    31861 tatatatagt ttcggggatc atcgtattga ttttagcagc tttactactt tatatcttag
    31921 ttcggggaat accgcacatt tcatggtcct tcttgaccga accttccaaa gcctaccaag
    31981 aaggcggtgg aatcgggatc cagctattta actcgattta tttgcttttg atcacgatga
    32041 tcatcagttt tcctatttct ttaggtgcgg gtatctatct ttcagaatat gctggaaaaa
    32101 actggctaac agatgtgatt cgcacgtcga ttgaaatctt gagctcgttg ccttctgtcg
    32161 ttgtcggttt attcggtttc ttggttttcg ttattcaatt ccagtatggt ttctcgatta
    32221 tttctggtgc attggctttg actgtattca acttgcctct tttgactaga acagttgagg
    32281 agtctttaca agcggtccat tacacacaac gagaagcagg attggcctta ggtttgtcac
    32341 gctgggaaac agtgataaaa gtggtggttc cagaagcgac accagggatt ttgactggtg
    32401 tgatcctaag ttctggaaga atttttggtg aagcagctgc attgatctat acggctggac
    32461 aaagtgcacc tgcgttagat tttacgaact ggaatccatt aagtgtttca agcccgatca
    32521 gcattttccg tcaagctgaa acattagctg tccatatttg gaagatcaat acagaaggca
    32581 cgatgcctga tggtgtttct gtttcggctg gcgcttctgc cgtgttgatt attgctgttt
    32641 tactgttcaa cttcggcgct cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag
    32701 cctaaggaga agaagcaaaa tgaaaaaata taactggaat gaaacaaatg tcatcaccat
    32761 gccaaaagag aaagaagtag cactatatac ggatgatcta catgtctggt atggcgacaa
    32821 tgaagcaatc aaaggagtgg atctggaatt tgaaaaaaat aagatcactg cactgattgg
    32881 tccttccggc tgcggaaaat ctacgtatct tcgttcgttg aatcgaatga atgatgggat
    32941 cgctaatacg aaaatcactg ggaaaatcat gtatcaaggc gtagatatta atgcgcctca
    33001 agtggatgtt tatgagatgc gcaaacggat tggcatggtt tttcaacgtc ctaatccgtt
    33061 cagcaagtcg atttatgaca atattacatt tgctttgaaa cagcacggcg aaaaaaacaa
    33121 aaagaaatta gatgaaatcg ttgaaacaag cttgaaacaa gctgccttgt gggaccaagt
    33181 aaaagacagc ttggacaaaa gtgccttggc tttatctggc gggcaacagc aacgtttatg
    33241 tattgctcgt gcgatcgcga tgaaacctga tatcttgctg ctagacgagc cggcaagtgc
    33301 tttggaccct atttcgacag gaacggttga agaaacactt gtaaacttga aagaagacta
    33361 tacgatcatc atcgtgacgc ataacatgca acaagcagct cgtatcagcg actatactgc
    33421 ctttttctat ttaggaaaag taatggaata tgacaaaact aacaagatat ttaccagacc
    33481 aaaaattcag gcaaccgaag attatgtgtc cggtcatttt ggttaagacg gaggcctcaa
    33541 catgacaaaa gagattattt catctaaaga tcttcatctg tattatggaa agaaagaagc
    33601 actaaaaggg atcgatctaa gcttcaatca aggggaaatc actgcgatga tcggtccttc
    33661 tggttgcgga aaatccactt atctgcgttc tttgaaccgg atgaatgacc tgattccgaa
    33721 tgtaacgatc accggaagtg ttttatataa agacaaagac atctatggtc caaaaacaga
    33781 tgttgttgaa ctaagaaaag aaatcggcat ggtattccag cagccaaacc catttccttt
    33841 ttctatctat gaaaatgtca tctatggatt gaaattaaaa ggggaaaaag ataaaaaagt
    33901 ccttgatcaa gtagttgaag aaagcctgaa ggcagcgtct gtttgggatg atgtgaaaga
    33961 caaattgcat aaaagtgctt tatctttatc cggtgggcag cagcagcgtg tatgtatcgc
    34021 acgtgttttg gcagttaatc cggaaatcat cttattggat gaaccaacaa gtgcgcttga
    34081 tcctgtttct actgggaaaa tcgaaagtat gctgttagaa ttaagagagc ggtatacgat
    34141 gatcatcgtg acccataata tgtctcaagc ttcacgtatt tcagataaga cggcattctt
    34201 tttagatggt cacttgatcg aatacaatga tacgaagaag atattcatga atccagaaaa
    34261 acaagagaca gaagattata tttcaggtcg atttggataa ggaggaaacg gaatgctacg
    34321 tacacaattt gaagaagaat tgctgaatct ccataatcag ttctacgaaa tggggatgat
    34381 ggtgagcagc gccgtgcaca agtcagttcg tgcatacatc aaacacgata aaatcttagc
    34441 ccaagaagtt atcgaaaacg atataaatat caataacatg gaaacacgct tggagaagaa
    34501 aagttttgaa atgatcgcat tgcaacagcc agttacaact gatttgcgta tgatcattac
    34561 ggtcatgaaa gctagctcgg atttagaacg tatggccgat catgcggtgt ctgttgctaa
    34621 atccacgatt cgcgtaaaag ggcagacgag aataccggaa atcgaaaaag agatctccga
    34681 tatgtccgat tatgtgaaaa aaatggtgga caacgtccta gttgcttatg tcaaaacaga
    34741 cgaaaaagac gcacgtacga tcgccaatat ggatcaaaga gtcaatgact atttcaatcg
    34801 aatctataat gcaacaatca aaaatatgca ggaaaatcct gagacagtca tcagtggaac
    34861 agactacttg aatgttgcca gttatctaga acggatcgga gactatgtga caaacatctg
    34921 tgaatggatc gtctacttgg ctacagggaa aatcactgag ttaaatacga accacaatga
    34981 gattttctaa actgaagctg tgattatgcc gtttgtttag gaaaagaggt tgtgaaatca
    35041 gcggttgtga aaaagctgtt ctgcatcaag taataagaac agtcaaacaa aaaatagctc
    35101 ctcatatttt tcgtttggct ggacttatta ccgcagatgc aagcttttga acaccgttta
    35161 ttcgggaaag ggtttgtgac aaaacatgtc acaaaccctt ttcatcattt catagaaagg
    35221 ataaagaatg caaaaaaaaa ttagcatcat cactatattt tttatttgtg tgcttacttc
    35281 atgggttatt cagcatcaag ccgctttata tgaagtacct gtcatcgaga tagaaaaagt
    35341 acgaataaaa gaggatcatc aattgattac aggaaaactg atgaacacgg atcaaaaagg
    35401 agaatcgatt tatttatcgg ttccttatca aaaaaatcaa atagaaacag caaatataaa
    35461 agcgagacaa atgtatctag tccaaatgca tggagatgaa tggcagctag tagcaaaaaa
    35521 aaatgatggc tggcttttct tcttcacaag tatcttcatt ggcgccatgt tgcttattgg
    35581 tggaaaacag ggtctatttg ctttaggaag tctcatcatc aatatcgttt tacttttact
    35641 tttgttgctc atctttacta aaacagaagg gatttctcta ttaaatatat ctatcctgtt
    35701 cgtcgttata gggatgatta ttagcatatt ggctttagat ggatggaata gaagcagtat
    35761 aatcaaaatt tcagctgcag ttacgagtgt ttttttagca ttttttattt gtcttttgac
    35821 aatgaatcat tggaaagacc aaggactgcg ctatgaggaa ctgaattatc tgacacgacc
    35881 gtatcgttct gtttttcttt ctagcgtact gattggaaca gctggaggaa cactcgatac
    35941 cgttatcaca gtcattgcga cattagaaga attgactaag cgacaaccag aaataacagc
    36001 gaaacagtta tggctttcag gaaggcaagt gggtcgagat gtgattggct cgatgaccaa
    36061 tatccttttg ttcgtctata tcagtgggtc agttccatcg cttcttttat atttaggaaa
    36121 tcaatggtcg ttcaaagaaa cgatagaaca gcatttatca ttggaatttt tacgcgtcat
    36181 tgctggcagc ttaggaatag tattatcgat ccctatctcg gtcctctttt ttctgactgt
    36241 aaggaggctg aaacgatgaa tgtacttatt atacttgttg ggattttagc aatcagcgtg
    36301 ctacttattg gcggtacgca aggtatgtat attcttttag gcttattcat caatttaggg
    36361 atctttttcc tgttgttatt cggttatcat cagaagtggc cgatactggc attgtcggtc
    36421 ataggatttt tattgattgc tgtggttatc ttatttttta tcaacggtta taatctaaaa
    36481 atgcgtgcag cttttgtgag tatactgatc tttttatttt gtttcctact attgcttcct
    36541 atcactgatt ttttagcaat ccaaggtttt acatcggtag aactagaaga attatctggc
    36601 ttagataaga ctttagcgat tgattttaga ttacttacga gatcgttgct tctgattagt
    36661 cttagtggtg ctgttttaga tgcgagtgta gcaatttcta gtgggacatt cgaagtatat
    36721 caggcaaatc cgcaattatc tttttaccaa ttgcgccatt ctagtttcgc tattgctaaa
    36781 aaaatattgg cgtcaacagt aatgacactt ctttttgcat tcatgggaag ttctttagcg
    36841 ttgatcctct ggtttattga tttagacatt ccttttcagc aagtgatcaa tgaaaaatca
    36901 tttgttctag aatatacgat ggctattctt accacattgt ccgcactact tgttcttcct
    36961 ttaacctgcg tgactacagc atatctcttt acaaaaaaga aagaacaact caagatggag
    37021 taaaagttac aacttaagtc ctatgacatt tttactgaat cagtgcataa tatggatgta
    37081 aggaaaagct tgcaaacaat tttgcttaag gaggcaattt ccatgaaaga aagagaacgt
    37141 attttagatt tagtgaaaaa aggaatcctt tcgactgaag aaggcttaga tttattagaa
    37201 agcatggcaa ctgaaaaaga cgaaaagcaa atcaaaaaag aagcagacaa ggtaactgct
    37261 agtcataaag aaaaagatca ggcaagtcaa ttgatcgata aacttgaaaa cggcgaagaa
    37321 gaaatttctg agccagttga tccaaaggaa agagaaagac aagatcaaga aaacttagaa
    37381 aagatcttag atgaactagc aactgaagcg aataaaactt cggcgcgtct agatgaagta
    37441 aatgctcaat tcgctgacaa taaggcagca cgcaatgaga aacaggaagc attgatgcag
    37501 ctgaatacaa aagaagaatt aggcgagttg acagaagaag aattagcaca gcgtcagacg
    37561 ttagaagcag aaatcaaaga attagaagct agtggcgata cactgttaga agaacaattg
    37621 aaattagaag cagaattaaa agatatccgt aagaatcaat ggtctgagaa aaaagaaacg
    37681 tttactgata agtttgaatt gccagatgat tggaaagatc aagcaacaga tacactgaat
    37741 caagtaggcg aaaaaatgtc agaagctgga tcacagttag gcaaattctt gaagaaaaca
    37801 ttccaaactg tttcagaaac agtgaatgac aacatggaat ggaaagatgt cagcttacgt
    37861 gtccctggga ttgcgacaac gaaatttgag catgaatttt actatgaagc tcctgcagca
    37921 agtatccttg atatcaaggc agcaaacgga aacgtgacgt taaaaacgtg ggacagcaac
    37981 gatgtgaaag ttgaagctaa gatcaaactt tacggaaaaa tgggtgctga accatttgaa
    38041 gcattctctg aacggagcca gattgaggtt aatgaagatc atatctcctt ccaaattcca
    38101 aataaacgtg tgcgtgcaga ccttgttttc tacttaccta aacgagtata cgaccacgca
    38161 gctattaaac ttctaaatgg caacatcatg attgaaacat tggaagctaa agatatttat
    38221 acaaaatcta cgaatggtaa catcatcgtg gaccaattaa ctgcaacgat gctggaagta
    38281 gaaggtgtaa acggcaatat cgatattcga aacgggaaca tcttagattc tattatcgaa
    38341 acagtaaatg gtacagtgac atttggtgcg acagcagaaa acctttctgt gtctttggta
    38401 aatggtgatg tacgtcttac gattaaagaa gataatttga aaaaagtaga agcaagttca
    38461 gtgaacggaa atgtcaaagt cgctttacca gatggcatcg gtttggaagg acatgctaaa
    38521 acaagtcttg gaagtatcaa cagccgtctg tccaattacg aagtagttcg tgagaaaaaa
    38581 gaacggacaa accaaatgtt gcaattccgt cgtgtttcag atggtgaaat cgcgcaagtg
    38641 caactttcaa cgacaacagg aagtatctat ttaaaagata cagataaata aagaggttgt
    38701 gaaagagatg ttcagccttg agcaataaga agcgattttg taaaatagct tcccctattt
    38761 tacaaaattg tgccttattg ccgatagtct atctcttgaa caccgtttac caagagatta
    38821 tgaacctgcc aattatcgcc gagtcacaag gaataatttc agaaaaagct cgtcacgttt
    38881 tatgaatatg gtaatttgtg accgagaatt ttgcagaaag acaccgatta agaagaaggt
    38941 tgtcacaacg attttcttca tttaaaatag tagaacagag gtgagacatg atgaaaaaaa
    39001 agttgacaaa atctaataaa aatgttgttt tgacagggac tttagcagga ataggagaat
    39061 acatcgggat tgatccgact gttatccgtg tgctttatgt attcctgagc ttagttgctt
    39121 ttggaagtcc aattatttta tacattttat tagctttgat tatcccatct gcgcgttctg
    39181 cacgaacaaa ctatggacat aacaatgcat attatgaaaa aaacaattat cgtgaacaaa
    39241 ctcgtgaaca aacaaaaaaa cgcaaagaag cggaaaaaat cgatgatgac gaatggagtg
    39301 acttttaatg tcgtactttc aacgtatttt agttaatacg ttaacattca tatcattggc
    39361 tgttcttttt cctgcgatgg tccatgtgag cagtatttgg acggccgttc ttgccagctt
    39421 cgtattgtct gtgttgaata tgtttgtcaa accgattttg acgatactgt ccctgccctt
    39481 tacattagtc acattgggat tgtttacgtt tgttatcaat gcagcgattc ttaaaatgac
    39541 ctcctttttt gtgggagcag aacattttag tttttcttca ttcggtgcag cgttgttagt
    39601 agctatcttg atgtcgcttg tcaatgtaat tgtcagcgaa cataacagta gaaaataaaa
    39661 gaaagctgtg ccgaactatc ggcgcagttt ttttatttag aatcaggaat gcgttttcta
    39721 ttacattggt aattaaataa aaacgttttt tttaattggt agtacttttg gctagacaat
    39781 gataaaatga tagagaacac tctaatagaa atgaggtagc atgaatgtca gaagttgtaa
    39841 aagttagcca attagtgaaa aaattatctt tggaaatcgt gacaggcgac gagaaaagct
    39901 tagaccgtgt catcgtaact ggggacatct cacgcccagg actagagttg actggttatt
    39961 ttaattatta ttcccataat cgtttacagc tatttggcag taaagaaatc agttttgcgg
    40021 aacggatgat cccagaagag cgtttgatca tcatgagaag attatgtagt gaagatatgc
    40081 ccgcatttat tatttcaaga ggattaccag ctccagaaga aatgatccag gcagcaaata
    40141 aaaatgggat agctgtactg cgttctccca tctcaacttc tcgtttatta ggagaattat
    40201 ccagttattt agatggtcgc cttgcccctc gaacaagtgt ccacggtgtt ttagtggatg
    40261 tttacggatt aggtgtactg attcaaggtg acagtgggat aggaaaaagt gaaacagcgt
    40321 tggagttgat caaacgcggc catcgattga tcgcagacga tcgagtagat gtttatcagc
    40381 aagatgaatt aacggtgatc ggagaaccgc ctaaaatcct ggaacatctg attgaaatcc
    40441 gaggaatcgg gatcattgat gtaatgaatc tttttggtgc gagtgcggta cgtggctcta
    40501 tgcaagtcca gttggctgtt tatctggaag catgggcaaa agataagaaa tacgaccgtc
    40561 tgggctctga agacacgacc gttgaaatcg cggaagtggg cattccacaa ataaaaatcc
    40621 ctgtcaaaac aggacgaaac gttgcaatca tcattgaagt agccgcgatg aatttccgtg
    40681 cacgtacaat gggctttgac gcaacgaaaa catttgaaga aagattaagt cgcttgattg
    40741 aagaaaactc aggcaacgac tagcaaggag tgacaatatg ttagcacaaa tcaatcgagt
    40801 tgcttttgag cttgtaggga ttcctatcta ctggtatgca ttgatcatcg tatcaggtat
    40861 cattatcgct atgtggctta gcagcagaga ggctgttcgg gtaggattaa aagcagatga
    40921 tgtgacagat tttatgttgt ggggattgcc tatctccatt attggcgctc gcttatatta
    40981 tgttttattt gatcttcccc agtatatagc tgatccaatc caaatattca atatccgttc
    41041 aggaggctta gctatttatg gcggactgat tgcaggcgcg atcacgctgt atttttttac
    41101 taaatatcat tttatttctt tgtggacttt tttagatatc gctgcaccaa gtgtattatt
    41161 agcacaggca atcggtcgtt ggggaaattt catgaaccac gaagcatatg gaccagacac
    41221 gacgcgaagc ttcttagaaa gtctgcattt accgcaattc atcattgata atatgtatat
    41281 cgaagggatc tatcgtcaac caacatttct ttatgaatca ctttggagtt tgattggatt
    41341 tattttgctt ttgtttttac gaaagaaacc acaccttttg aaaaaaggcg aagtcctttt
    41401 atgttatcta atgtggtata gtttcgggcg tttctttatt gaaggattac gtacagacag
    41461 tctttacttt ttaggtgtga tccgtatttc tcaattatta tctgctgtgt tatttgtcgg
    41521 tacattgatt ctatttattt ggcgcagaaa aaaaggaaat ttaccggatt atgaccgctc
    41581 attaggaaaa aatcaacaaa ttatctgatt tttagagcgt taaaaatgaa aaaaatttca
    41641 ggagtggtaa aatgaattat agagtagcgg ttttaggacc aggctcttgg ggtactgctt
    41701 tggcacaagt cctcgccgaa aacggacatg acgttcggat ttggggacat cgtgcttcac
    41761 aagtagaaga aatcaacacc caacacacga atcaacgtta tttaccagat cattatctac
    41821 ccgattccat ccaagcattc accaatatgg aagatgcagt aaaagacgca gatgcggtgc
    41881 tattcgtcat tccaacgaaa gcaatacgtt ctgttgcaaa agaactagtg cctaaattga
    41941 atacaaagcc agtgatcatc catgcaagta aaggattaga acagggaaca cataaaagga
    42001 tctctgacat cttgttagag gaaatcccag cagaaaaaag aaaagctgtt gttgttcttt
    42061 ctggaccaag ccatgcagaa gaagtagcaa aacatgacat cactacgatc acagctgcaa
    42121 gtacagatgc aaaagcagca aaatatgtac aagagctgtt catgaataat tattttcgga
    42181 tctataccaa tcctgatgtg atcggtgtag agatgggggc agctttgaaa aatattattg
    42241 ctattggtgc tggcgctatt cacggcttag ggtttggcga taatgcaaag gcagcaatca
    42301 tgacgcgcgg attagctgag atcagccgtt taggtgtagc aatgggtgcc aacccgctga
    42361 cctttatcgg attaagcgga ataggcgatc tagtcgttac ttgcacaagt gttcattcta
    42421 ggaactggcg cgcaggcaac ttgttaggac aagggcagcc ccta
//
LOCUS       DACGLI010000024        40868 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.025, whole genome shotgun sequence.
ACCESSION   DACGLI010000024 DACGLI010000000
VERSION     DACGLI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.025"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(137..2212)
                     /locus_tag="IXT22_001337"
     CDS             complement(137..2212)
                     /locus_tag="IXT22_001337"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAQ4862714.1"
                     /translation="MAKDLLLEIGLEEIPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKQYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2214..3131)
                     /gene="glyQ"
                     /locus_tag="IXT22_001338"
     CDS             complement(2214..3131)
                     /gene="glyQ"
                     /locus_tag="IXT22_001338"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4862715.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3515..4327)
                     /gene="recO"
                     /locus_tag="IXT22_001339"
     CDS             complement(3515..4327)
                     /gene="recO"
                     /locus_tag="IXT22_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAQ4862716.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4470..5369)
                     /locus_tag="IXT22_001340"
     CDS             complement(4470..5369)
                     /locus_tag="IXT22_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAQ4862717.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5384..5785)
                     /locus_tag="IXT22_001341"
     CDS             complement(5384..5785)
                     /locus_tag="IXT22_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAQ4862718.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5763..6239)
                     /gene="ybeY"
                     /locus_tag="IXT22_001342"
     CDS             complement(5763..6239)
                     /gene="ybeY"
                     /locus_tag="IXT22_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAQ4862719.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6256..8448)
                     /locus_tag="IXT22_001343"
     CDS             complement(6256..8448)
                     /locus_tag="IXT22_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAQ4862720.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8472..9443)
                     /locus_tag="IXT22_001344"
     CDS             complement(8472..9443)
                     /locus_tag="IXT22_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAQ4862721.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10149..11528
                     /gene="brnQ"
                     /locus_tag="IXT22_001345"
     CDS             10149..11528
                     /gene="brnQ"
                     /locus_tag="IXT22_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4862722.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            complement(11682..12128)
                     /locus_tag="IXT22_001346"
     CDS             complement(11682..12128)
                     /locus_tag="IXT22_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAQ4862723.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12155..12331)
                     /locus_tag="IXT22_001347"
     CDS             complement(12155..12331)
                     /locus_tag="IXT22_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAQ4862724.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12493..12921)
                     /locus_tag="IXT22_001348"
     CDS             complement(12493..12921)
                     /locus_tag="IXT22_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4862725.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13013..13873
                     /locus_tag="IXT22_001349"
     CDS             13013..13873
                     /locus_tag="IXT22_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAQ4862726.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            complement(13965..14258)
                     /locus_tag="IXT22_001350"
     CDS             complement(13965..14258)
                     /locus_tag="IXT22_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4862727.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(14330..16057)
                     /locus_tag="IXT22_001351"
     CDS             complement(14330..16057)
                     /locus_tag="IXT22_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAQ4862728.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            complement(16271..17197)
                     /gene="trxB"
                     /locus_tag="IXT22_001352"
     CDS             complement(16271..17197)
                     /gene="trxB"
                     /locus_tag="IXT22_001352"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAQ4862729.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17342..18775)
                     /gene="ascB"
                     /locus_tag="IXT22_001353"
     CDS             complement(17342..18775)
                     /gene="ascB"
                     /locus_tag="IXT22_001353"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4862730.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSNN"
     gene            complement(18775..20178)
                     /locus_tag="IXT22_001354"
     CDS             complement(18775..20178)
                     /locus_tag="IXT22_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4862731.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            20409..21311
                     /locus_tag="IXT22_001355"
     CDS             20409..21311
                     /locus_tag="IXT22_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4862732.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            complement(21351..23231)
                     /locus_tag="IXT22_001356"
     CDS             complement(21351..23231)
                     /locus_tag="IXT22_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4862733.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVRQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(23327..24178)
                     /locus_tag="IXT22_001357"
     CDS             complement(23327..24178)
                     /locus_tag="IXT22_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4862734.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(24504..26288)
                     /locus_tag="IXT22_001358"
     CDS             complement(24504..26288)
                     /locus_tag="IXT22_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862735.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(26288..28039)
                     /locus_tag="IXT22_001359"
     CDS             complement(26288..28039)
                     /locus_tag="IXT22_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862736.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIVMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPVKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(28180..28404)
                     /locus_tag="IXT22_001360"
     CDS             complement(28180..28404)
                     /locus_tag="IXT22_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAQ4862737.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            28655..30241
                     /locus_tag="IXT22_001361"
     CDS             28655..30241
                     /locus_tag="IXT22_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAQ4862738.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            complement(30307..32082)
                     /locus_tag="IXT22_001362"
     CDS             complement(30307..32082)
                     /locus_tag="IXT22_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAQ4862739.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(32295..33197)
                     /locus_tag="IXT22_001363"
     CDS             complement(32295..33197)
                     /locus_tag="IXT22_001363"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAQ4862740.1"
                     /translation="MLLGSHVSMSGKKMLLGAAAEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            33476..35821
                     /locus_tag="IXT22_001364"
     CDS             33476..35821
                     /locus_tag="IXT22_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4862741.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            complement(36158..37159)
                     /gene="ccpA"
                     /locus_tag="IXT22_001365"
     CDS             complement(36158..37159)
                     /gene="ccpA"
                     /locus_tag="IXT22_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAQ4862742.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            37369..38475
                     /locus_tag="IXT22_001366"
     CDS             37369..38475
                     /locus_tag="IXT22_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4862743.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            complement(38534..39136)
                     /locus_tag="IXT22_001367"
     CDS             complement(38534..39136)
                     /locus_tag="IXT22_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4862744.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(39139..39579)
                     /locus_tag="IXT22_001368"
     CDS             complement(39139..39579)
                     /locus_tag="IXT22_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAQ4862745.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            complement(39704..40642)
                     /gene="galU"
                     /locus_tag="IXT22_001369"
     CDS             complement(39704..40642)
                     /gene="galU"
                     /locus_tag="IXT22_001369"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4862746.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            complement(40657..>40868)
                     /locus_tag="IXT22_001370"
     CDS             complement(40657..>40868)
                     /locus_tag="IXT22_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HAQ4862747.1"
                     /translation="EVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQK
                     EIKTAAKEIMLRDGKKENEFSLTIF"
BASE COUNT        11568 a         8656 c         7306 g        13338 t
ORIGIN      
        1 ttttaaaagt tacacaaaaa ataaaataac aaaaaaatta acattgaatt aataatagtt
       61 atttatattt ataacaaata aaccagagaa atagcctatt ttgtgcctgt tctctggttt
      121 atttacatat tagaaattat tttgtgatga tttgatctaa acttgctagt gacaaagcca
      181 tggcagcaat ttgacttaat tgcgttaatc ggttcttacg tactgctggt tcttctgcca
      241 tgaccatcgt ctgatcaaaa taattttcga tcagtgggcg aaggcttaca agctgatcat
      301 aattttcgtt gatcgtttgg tcagcaaagc ttgttttcat tgcctctact gctttgtgca
      361 gttctttctc cgcttcgttt tcgaacagtt cagggtctac ttctgattgt ttttcaagct
      421 ccgctttttt cgctaagttc acgacacgtg tcaaagcttc catcgatggt ttgaagtctt
      481 catctgcaag atgctgcttg aacaattgtg ctgctgcaaa tacttttgtc agatcttttt
      541 gttctgcatt caaaacagct tcgatgacat catgacggat attcttcgtt gtcaataatt
      601 ggcgcagacg gcctttgata aagtcgatca cctgttgttg tcccgctgac aagccaatgc
      661 caaaacgatc cgtatcttta ctgataactt cactaatcgt ttcttgcaga acagacaaag
      721 gaaaggccca ttttttcgat tcgatgattc gaacgacacc atatgcttga cggcgcaaag
      781 catatggatc gtttgagcca cttgggatca tcccaactgc aaagaaagaa aagatactat
      841 ctaatttatc agcaatcgct aaaacagaac ctactgtagt ctcaggtaaa tctccttcac
      901 tggatatagg catgtaatgt tcacggatcg ctgttgctac ggctggtttc tcgcctttaa
      961 gcagagcata tttttcgccc atgatccctt gtagttcagg gaattctcct accatgttgg
     1021 ttactagatc aaatttatag atttcagcag cgcgttgcag atccatcaat tcttcctcag
     1081 atagtcctac ttgttcgcct atgatgcgag cgatgacttg tacccgttgc attttctcat
     1141 agatgctacc gattttttca tggaaagtaa cagtttttaa tttttcaacg tattggtcga
     1201 ttgaagcttt cttgtcttca ttataaaaga attccgcatc ttctaaacga gcagtcaata
     1261 ctttttgatt gcctcgtacc acattttcca attttacccg atcgccatta cgagcagaaa
     1321 taaaatgagg aagcaacata ccttgatcgt tccgtacttc gaaataacgt tgatgttctt
     1381 tcatagaagt gactagtact tcttcaggaa cagatagata tttttcttcg aagtcgccag
     1441 aaaagacagt tggatattcg actaaattgt tgacttcttc tagtaaatct tcatctagat
     1501 caatgatcca gtgatttttt tctgctaatt cgtttgcttg tgtgatgatc atttcttttc
     1561 ttttttgcgg tgaagcaata acaaattgtt cattcaattt ttcttcgtat tgttttgcat
     1621 gcgtaaatgt cacatcttcg cctaagaaac gatgacctct tgaagctctg tctgttttga
     1681 catccaagat ctcaaacggg attatttcgt catctaacaa tgccacgatc cagtgaatag
     1741 ggcgaatata ttcaaaatcg tattctgccc agtgcatcgt tactgggaaa gtgaggcttt
     1801 taatgacatc tgctaaacct gtcaatactt cttttgcttc tttgccgtga gtgtatttcg
     1861 ttacatagac atattccacg ccttttaatt ctctaaaagt gatagcatct gtcgtcagac
     1921 cttgtccgcg gacaaatcct tcagctgctt tcgtccagtt tccatctgcg tccaaagcaa
     1981 tttttttggc tggtcctttg acttcttctt cgctgtctgc ttgacgttct ggaatgtttg
     2041 ttactttgat tgctaagcgg cgcggtgtag aaaacgtttc gatcgtatca taagtcaatt
     2101 ggttttcatc taaaaatttt gctgtttttt cttctaattg tttcatgctt ggtgtgacta
     2161 catgagcagg tatttcttcc agcccgattt caagtaataa gtcttttgcc atcttattca
     2221 gcctccttca cgttttctgg atttgctgtg tttttattca ataaagggaa tcctaatttt
     2281 tcgcgttctg ccacaaagat tttggctaca gcacgagcca tgttgcggat acgggaaaga
     2341 taacctgcac gctctgttac ggatactgca ccgcgagcat ctaataaatt gaatgtatgg
     2401 ctacatttca aaatataatc atacgctgga tgaacaagat tttcatcgat acagcgttta
     2461 gcttcttttt caaaacgatc aaaattgctt agtagcaggt cttggtcgct tacttcaaaa
     2521 gaatatttag aatgttcata ttctggttgt ttgaagatct caccatattt cacgccatca
     2581 gcccattcca gatcataaac actttcaact tcttggatat aagaagcaag acgttctagt
     2641 ccataagtga tctcagaagt aactggttta caaggtagtc ctccgacttg ctggaagtat
     2701 gtgaattgtg tgatctccat cccatcaagc catacttccc agcccacacc ggcacaaccc
     2761 atcgatgggt tctcccagtt gtcttcaaca aagcgaatat cgtgttctaa tggatcaatt
     2821 cctaaaagac gcaagctttc taaataaagc tcttggatat tttcaggtga aggtttcatt
     2881 acgacttgaa attgatgatg ctgatacaaa cggtttgggt tttctccata acgcccgtca
     2941 gctggtcggc gggatggctc tacataagca gcattccatg gttccggtcc gattgcccgt
     3001 aagaatgtat atgggctcat cgtacctgct cctttttctg tatcataagc ttgcatcagc
     3061 atgcagccgt ttgatgacca aaatttttgt aatgttaaaa tcatatcttg gacggtcaat
     3121 tttttactca tctgttttgc ccctttcaat ttttaagcgt tgctgtcaat aagaatacag
     3181 gaaagaaaac gacaaaaagt ccctatgtct gattacagac atagggacga ataatttcgc
     3241 ggttccaccc tacttccgaa taaagattcg gcagcttcat ttatcgtact cgcaagtgcc
     3301 tcttcaaaaa tcgtttgggt ccggcttcca ctctcccgaa ctcgctaaac cacgtgtttt
     3361 ttactgatct tggtcaatgt acgtattcat tttgcagttt tctggtttgt ataatagatc
     3421 ctctcagtga acgatctatt taatctacgg ttaataatag acggaagtcc ctgtatttgt
     3481 caaatagttt tgattttttt gttgtatctt tcatttattc ttctttttca ggtatctctt
     3541 tttcaggcat atttttctct ggcgtcttta atacgtgtgc ccaagacttc atttgatcaa
     3601 tgaacttttt gctttttaga tgaataccga catattcatc atacaactgg tcaatgaggt
     3661 cacggattgc ctgcttcgtt tcttctttca agtggattcc actgatctta tcataagaaa
     3721 tagccgaaaa cattcgaacg aaataaacag cgcgaggatc tgcatgataa cggtgttcgt
     3781 ccattggcca gtgtttctcg catatcacac cgccatattt ggaagaatag tcaaattttc
     3841 cttttgtttc cccgcatacg acacagtgcg tccaaattgg cgcgattccg aagcgttgca
     3901 gtatttgcac ttcaaagata ttcgtgatga tttctgcatc atctccttgg tccatccgct
     3961 gcagagcttg ttgcgtaaat tggaataaat gcgggtcata ttgatgatct tcgattgctg
     4021 catctactag atttagcaaa tacgtaccat aaccgctcaa aaagatatct tcttggatgt
     4081 tccgaaacgc atggacgtct ttgacactgc ttaaaaacga caaaccttca cttcgaaaat
     4141 taccgatata gactgcttcg gtaaagggga gcaaagccgg agctaatggc tgattttgcc
     4201 gatggattcc tttgatataa aacatcattt tgccagaaga ttccgtaaag attttgacta
     4261 atttatcttt ttctttgtaa ttacggctag ataaaatcaa gcctttcgat tctgcaagct
     4321 ggctcatatt ctccctccta aaaaataaat ctggaaaagc agattctgcc gatccagatt
     4381 atttatgttt cgatcttccg ctgtttttct caacgtacgg atttttatcc agtttatttc
     4441 tatacctaac ctataagaag tccagaatat cagtactcgt cttttcggta gccgaagtct
     4501 tgcagataga cttttttgtc tcgccagtct ttttggactt tgacccaaag ttctagaaat
     4561 actttgtctc ctaaaagatt ttcgatatcc tttcttgctt tcgttcctac ttgcttcagc
     4621 atttttccgc ctttgccgat aatgattcct ttttggctat ctctttcgac gatgatcgtg
     4681 gcctggatat ggattttatc attctcgttt cgcttcatcg aatcaacaac gactgcgaca
     4741 gaatgaggca cttcgtctcg tgttaaaaac aagactttct cacggatcaa ttcagaaacg
     4801 atgaagtatt caggatgatc agtcacttga tcatctggaa aatattgtgg gccctctggc
     4861 atttcactga ctaatacatc cattaagcgt tcgacattgt ttccttctgt agcagagatc
     4921 ggaatcactt gtgcaaaagg catctgcgtc gaataatctt cgatgattcc cagcaactcg
     4981 tctggatgga tcttatcgat tttattgata atcagataaa caggagaatg cacgtttttt
     5041 agacgttcaa taataaaatc gtctccccgg ccacgttttt gatcagcact gatcataaat
     5101 aagactgcat ccacttcttt caacgcactg taagctgctt ctaccataaa atctcctaga
     5161 cgatgctttg gtttatggat tcctggtgta tcgataaaaa tcagctgagc ttctggtgta
     5221 gtatatactc cttggatttt atttctagtt gtctgtgcct tgtcactcat aatggcaatt
     5281 ttttgaccca cgattcggtt caataatgtg gattttccta cattcgggcg gccgacgatt
     5341 gcgacaaacc ctgatttatg ttctggcata tacgttctcc tttttaatta aacaacaaat
     5401 gatatatttt agggacaaat aaaatcaacc caatgatgac agcaaaacaa gcggtcacta
     5461 aaactgctcc agctgccata tctttgattt ttttcccaat cggatgaaaa tgaaaatccg
     5521 taaacatgtc cactacattt tcaaaaacag tattgatgat ctctactatc caaacgagaa
     5581 aaacagctaa aagcagccat aaccactcta tccgatcaag ctggaaaatc acgcccataa
     5641 ataaagcaag gataccgaac gcaacatgtt tcctcatatt gcgttcttcc tcaaaaacgg
     5701 ttttgactcc ttggacagca aattccacag acatcaggaa atgtttgttt ttctctacgt
     5761 ttttatcttt tgagtccata ggcatccaag atctctttct gtaaaccaaa catttctttc
     5821 tcatcttctg gtgtcatatg gtcatacccg ttgatatgca agaatccatg taccgctaaa
     5881 aagccaagtt cccgatcata tgaatggccg taagcttctg cttgttcagc agcacgttca
     5941 atagagatca tgatgtctcc tagtacacga ggtaatggat tctctccatc ttcaaaaatc
     6001 actgggattt cgtcttcgcc ttcttcttcc agagcaaaac tgatgacgtc tgtcggtgca
     6061 tcttttccac ggtaatcacg attgattact tggattgccg cattgtccat gaaagtaaca
     6121 gacatttctg tttcctctgg cagctttaaa taagatgctg caaattgcag caagtcatcg
     6181 atttctttca ttttctcttc tgagacttgg tttgtttcat ccataaaggt aatatccatt
     6241 atacatcgct tctttctatt cttcttgttc ttcctttatc ttctcaactt ctgttttcat
     6301 tttaggatat ttgatccgag aatggaaggt gctacttaaa ccgctgatta atgatttttc
     6361 cacttttcgg atttctttca aggtcagtcc actatcgtct aattgaccat cggaaatacg
     6421 ctcttcgata agattatgga caaaactttc gattttttcg ctcgtcggat gatccattgc
     6481 ccgtactgca gcctcacaac tgtcagcaat attgacgatc cctgcttcac gactttgcgg
     6541 ttttggtcca ggataacgga attgctcttc tgttacttcc ggattgcgtt ctttcgcttt
     6601 gatgtagaaa taacgcatta gcgtggttcc atgatgctgt ttgcaaatat cgatcaccat
     6661 ttgcggcata ttataatctt ccaatatttt ggctccatct gtcacatgtc caaagataat
     6721 atgtttactg tcttctggca ataagaaatt gtgcgggttt tccgctcctg aaggcaagtt
     6781 ttcaacgaaa aagctagcat gtttgatctt gccgatatca tgataatagc aagctactcg
     6841 agttagcaaa gaacgtccgc cgatttctgc tacagcgtta gcacttagat tagctaccat
     6901 catactatga tgataagtac ctggcgcttc ttccagcaac tgtttcaata aaggatgatt
     6961 tggattgctg agttcattta atacaattac actgtcatca ttgaccatca attcaatata
     7021 tgggtgtaga ccgatcgtca gcaagaatga gaagagtgca ccagtgaacc cgcagacgag
     7081 cattaaccaa gtcgttgcat caccaaagct cattccttga tagacgatca aaatgacatc
     7141 catcatcaca ggaaaaataa tgacccacat ggcagcagat aatccttgtt ctgagatccg
     7201 tttgcgtctg acaatcgttg ccatgagccc agagaaaaca taagacatca agataatcgt
     7261 tagaaagttc gtgccaatcg aatcataaaa aatgaaaagt gcggatactg cttggaaaat
     7321 accagccatg atccctgctc ttcgattcaa gaaaaagctt aaaacaagtg gtgcaaaagc
     7381 agcgggataa aacagcggga tataagtagc ttgttccgtt tggaataatt ggaaaaattt
     7441 catcagcact atgctgactg acatagctgt cacatagaaa agcacgtatt ttgttctttc
     7501 tcctgcattt tggaattgaa gtgaattata aatcagtacg ccgatttgaa gcaaaacagc
     7561 taaaaccatg gcaattagcg gaaaaatcga agttgtttga ttagtcagtc ctagtaattc
     7621 caattttttc atagctgaag catcgatttg attaccttca cgaacaatga tttctccttg
     7681 gaagatcatc actggttgta cagcttctcg tgcggattgt ttcaattctt ctgtcttttt
     7741 ctcattcaat acgtcattca ctacgatacc ttgatccact aagtagcgaa tcatttgttg
     7801 ttgtgctggt gtgacattca aatattggat ttgctcttct gcttcttgtt taaaagcttc
     7861 caattcactt tcacgaactt gtttgctcat ctgttcgtca atgagcttca gactctcatc
     7921 cctcacagta tgaatctcag tttcagtcat ttcaaatatc gtcgaataaa aattgttcgg
     7981 tagtttttga taaaacacaa cattttctgc attcacattt tcaaaatttt tcttcagcgc
     8041 ggcgatccgc tcttctgtag taggctttgg gatattttca tcttcctttg ccttatcaat
     8101 cttttcgtca taagatttgt tgatggcatc attcgtctta tcgatcaatt caaatagttg
     8161 cttgatccga ttgttctggt catctgcaag atctttttgg taagtgtatt ctggagtgac
     8221 tgcttctgct gccagttttc ttttttgttc ggtttcttcc gtgttctcga tcgttttgtt
     8281 cgcacggata ctttcttctg ctacttggcc ttctctgaaa tcattggcct tttgtttgac
     8341 actactaaat gtaacgccgc agataatgat aaaaaacaag aacagcagga aaggcaatgc
     8401 tgcctttcca agtttttctt gtagtttctg cagtgtttta ttcaacatgt gcttatcctc
     8461 ctaagcaaag cttattcttg atggagatct gccttttcat aagctttgat gatttcggca
     8521 actacagggt gccgaacaac gtcacttgct tcaaaattaa caaaatcgat tttcttgatt
     8581 tgctttaatg ttcgttctgc atgaacaaga ccacttgtcg tccctcgagg caagtctatc
     8641 tgacttgtat ccccattgac aatcattttt gattgataac cgagacgggt caagaacatt
     8701 ttcatctgag cgactgtcgt gttttgtgct tcgtccaaga taacgaatgc atcatccaat
     8761 gttcgccccc gcatgtaagc taaaggtgcg atttcgatta cgcctcgttc catcaatcgg
     8821 ttcgtatgat ccaatccaaa aatttggtat aaagcatcat aaacaggccg cagataagga
     8881 tccacttttt cttttagatc cccgggaaga aagcctagat tttcacctgc ttccacagca
     8941 ggccgcgtca aaatgatttt ttgcacttca ccttttttca aggcagcgat tgctaatact
     9001 actgcaagaa aagtttttcc tgtaccggct ggtcctacgc caaatacgat atcatgtttg
     9061 gctaccgatt cgacatattt cttttggccg ctgtttttta cccgtatagg ttttccatta
     9121 cggtctttga cgatctcttc ctcatacatc tcaacaaaat aatctaatgt acctttttgc
     9181 cccattttca atgccgtcac aacatcgggc gtacttacgt ggattcctcg tttgatcaat
     9241 tcctgtaatg tccgaatgac tgaggcagcc aaggaaatct gggattgctc accaatgatc
     9301 tgaatgattt ctccacgtgt atggatggtt gtttccgttg tttcctcaat cagttttata
     9361 tgcttgtcgt gtgcacctaa aagcatgctg acatcatcag cagccgtcaa tctaatctct
     9421 aaagaactag actcttccgt caaaaataga catccccttt ttttcgattc attctttcct
     9481 attttaccat actcagaaga aactatatag caaataagaa aaggttctaa aagagttgct
     9541 taaccataag taccaagaaa cgttaaaaaa ctagccgctt ccattctcta aaggtctcgt
     9601 ttgaataaaa aaagctgatc atgtaagcta tgcataagat agaggacaag tattccgtct
     9661 aacttagcaa gtattctctg ggtatttttc ttgtttcaaa aaaagaaaac aaaatatttg
     9721 aaatattctt gcatttcaaa aaaaacaggt gtattataac gtcaacaaat aaatatacag
     9781 caaagcgtcg aggaaaacag taggctattc agtgatttat tcccagtgag tcatgtaagt
     9841 gagaaatgac aataaatcga atagacgaac atcatttccg agtcaatgtc gaaaacgtag
     9901 atcattgtgg ctgcctccat tatcaggcta gcggataact ttatcgaaaa gcgtccgtga
     9961 atgaagaagc ttttttaagc gaaaaaaggt ggtaccgttc tagaatctag agcccttttc
    10021 ccaagtggaa aagggctttt tttatatttt aaggtggtgg ttttcatgga atctgatatt
    10081 agtggtattt ctagtttctg caacgtttat tttgttactc aaaatgataa ttattggagg
    10141 aaaaatttat ggaagaaaca aaaacttatt catggaagca attattgatg gtcagttcac
    10201 ttatcttcgg gatgttcttc gggtcaggta atctgatctt tcctgtacac ttaggtcaaa
    10261 tggctggatc aaactggatc agcgctggtg taggatttgc catctcaggc gctcttttcc
    10321 cattattagc tatcttagct gtagtagtga caaaaagtga tggtctgtat gacttagcta
    10381 aacctgtcgg aaaatggtat gctgccttgt tcttgatcct tgttcattta acgatcggac
    10441 cattctttgg tacaccgcgg acagcagcaa ctgcttttga aatggctgct aaaccctttt
    10501 tgcctgaaaa atatgattca ttaggtatgt ttttattctc tgctcttttc tttttacttg
    10561 cttatttcct tactgtacat ccaacacgtt tggtcaaata tgtcggaaag tatttaaact
    10621 ccttgtttct tgcattatta gctatcattt ttgtcgtttc tttattccaa cccatgggga
    10681 atctaaacca atctgctgca gattcttatc agacgaacgc tttgacaaat ggcgttttag
    10741 aaggatacaa cacggttgat gcagtagctt tacttgcttt aagtgtcact tttgtccatg
    10801 cagttcgtga tcttggtttt aaagataaaa aagtcacaga attaacagca aaagctggta
    10861 gcctgagcgt tgcgttagaa gtcatgattt attttggtct ggtccttctc ggtgcgatga
    10921 gtttgaataa gatgtcttta tcagaaaatg gcggaactgc actttctcag atcactaatt
    10981 tttatttagg taacttcggt gctagcttct taggggtaat ggtcacatta ggtgtcttca
    11041 ctactgctat gggactcgtt gtttcttttg cacaagattt ccataaactg ttccctaaag
    11101 tcagttatat gacatggctg cggttaacga cttttgtctc ttttgtcgtt gcgaatgccg
    11161 gattggataa tatcatccaa tggtctttac cagtattgat gcttttgtat ccattgtcac
    11221 ttgcgttaat cttactttcc ttaacagcaa aattcttcca aaagagtcca tttgtctatc
    11281 aagtaacgat gttcttttct gccgttccag ccgtattgga tatgttggca aattcgcctg
    11341 cattagtgag tcagcaaact gtcgtagcaa gcttactagg attttatcat cattatgttc
    11401 cttttgctgc attaggtctt ggctgggtcg tcccaacgtt gcttggttac gctggcagct
    11461 tgctctttta ttatgtatat cgcgtatcag gatataaaca agaagcaagt gagttaccag
    11521 aagaataacc aaatcaaaca caatttaaca taagagatat taaacaggaa aaaaacagct
    11581 agaagaaaga ataagattct ttcttctagc tgttttttag ttcttttttt acgaacacaa
    11641 aaaactgcgg ataatcactg tccgcagttt aaatgataaa attaagattg taatagttct
    11701 ttcacaatcg cattcacttg gtttccatct gcttttcctt tgactttagg cataattgca
    11761 cccataactt tgccaaattc tttcattgat gaagcaccag tttgagtgat tgcttcttga
    11821 acaagttgtc gaatttcttc gtcggaaagt tgttccggca tatatttttc gactattaca
    11881 atttcacttt ttactttttc agctaaatcg tcacgtcctg cttcttcaaa ctcatgcaaa
    11941 gaatcacgtc gctgtttcat ttcacgagac aacaccgtta gttcttcttc ttctgtcaag
    12001 tcgtgacctt ctttaatctg ctcgttttgt atagatgact tgatcattcg gatgacttgt
    12061 aaagattcct tatctttcgc tttcatcgct gctttcatgt catcgtttaa tctacttagt
    12121 agtgacacac taccaactcc aattcatcac agaactagaa ttttttgcgt tttctagctg
    12181 cttcagattt tttcttgcgt cttacacttg gtttttcgta gaattcacgt ttacgagatt
    12241 cttgtaaagt acccgctttt gacacggaac gtttgaagcg acgaagagca tcgtcaagtg
    12301 attcgttttt gcgaacgact gtttttgaca tgttaattcc ctccctccga gcttaaaaag
    12361 taaccgtaat tgttattgaa atatatctca aaaaacaaga ctgtcctgta aatattatat
    12421 ctaatgctgt tttgaccgtc aaggaaatct tgcttttttt taaaattatc aaatgttatt
    12481 ttatttaaat ccttattgac aattttcaca tcttccgaaa atctcgaatc tatgcccttc
    12541 gatcgtgcat ccacctagct gttcttcgaa ataattcatc ggacacatat ggatttcttt
    12601 cgttgttccg cacactgtac agataaaatg atggtgatgg ccgattttcc cctgacagca
    12661 atgaaaacga aacttcattt ctccatttaa atcggtttct tccagtaaat cgatctctgc
    12721 aaaatcatgg agattccggt aaatcgtatc ataacttacc cctttgaatt cctgattcat
    12781 atagtcaaaa acttctttag cagatacgta gcggttacgc ttcactaaat aagttaacaa
    12841 tgcttctctt tttttagtat atttaaaacc gttatttttc aatgtttcta atgattgttc
    12901 gatcaatgtc tgttttttca tgacttattc ctccaaatca aaatgattac gaagtacgca
    12961 ttctagagta tggtataata aacataaaaa aaatgcaagt gaggttttat ccatgtcttc
    13021 cgattctaca gaaatcgtta ctttttttgt catctccgac tctgctggag aaactgcgac
    13081 aaaactagcg caagctacta tggctcagta tcctaccgtt gagttcaacc tattccgcag
    13141 aacgttcgtg acagatgaaa aaacattaag gcaggcattg caagatgcat tagaagaaaa
    13201 agcacttgtc ctgcatacat taatcaatca agaactgatc gagataacac gttctttttg
    13261 tgaagaacat caattattta gttttgatgt gatgacgcca ccgatatcag aaattgaacg
    13321 tttaactggt atcaagccaa ttcggcaacc tggtgccctc catttattga atgagaacta
    13381 tttcaaacgg atcaaagcaa tggaatttgc tgtaaaatac gatgatggga aagatcctcg
    13441 tggtttttta gaagcagatg tcgttttgct aggcgtatcc cgaacttcca aaacgccttt
    13501 gagcttgttt ttagctaaca aaaatttaaa agttgccaat ttacctttga tcccacaagc
    13561 acatattccc aaacagcttt gggagatcga tcctaaaaaa atcgtgggac taacgaataa
    13621 cccagatatt ttaaataata tccgtaaaga acggatgcgc tcttacggat taaaccctga
    13681 tactgcttat tccgatatcg aaaaaattag agctgaactt gattttgcga atgatcttta
    13741 tgaaaaacta ggatgtgtag tgatcaatgt ggcatcttta tctattgaag aaacggcttc
    13801 gcttattttg aatgctttag acctagaaga tcatagttat tatggaactg aaacaacaga
    13861 aaaaagcgat taatcatttt tgtctttttc ttaaaaaaca ctggagtgtg acaacgaaga
    13921 aatttcgttg tcacactcca gtgtttatct atttgcacct atcgttattg atgttccaca
    13981 tgtttgagtg tctggttcaa aatatccagt acatgagaat catcaagact atacaaaatc
    14041 gcttttccct cgcgatgaga cttgacgaca tgattttctc ttaataaacg tagttgatgc
    14101 gatacagcag actgctccat ttccactgct tgggtgattg ctgtcacatt ttgttccccg
    14161 tctttcagat atagcagaat tttaagacga gtggggtcac tcaacatttt gaataattga
    14221 ctgactttct ctacttttga tttttgcgtg tctggcaatc cattcacctc caacttgaaa
    14281 aaagactgac ttctaaagtt taccactttt tccatcagtc tcaagttttt tattcttctg
    14341 tcatcttttt gataatcgct tcataagagg ctactttttc ggctgcgtct tctgtagagc
    14401 ttccttttac accaatataa aacttgattt tcggctcagt tcctgaaggg cggatagcga
    14461 tccagccatt ttcttccaat gtatacttca atacgtcgga tggcggtgtt gttagttttt
    14521 ctacgtttcc ttcacggtct gttctcgtca attctttaaa gtcttctgtt tgaataactt
    14581 ttgctccggc aaattctgtc ggtgcttctt tacggaattt ttccatcaaa gcagagattt
    14641 tcgcagaacc ttcttgtccg ctcattgtca cagaaatcgt tttttctgcg aaatagccat
    14701 aggtttcaaa aatcgtttgc aagccgtcat acaacgtttt gccttgtttt ttatagtaag
    14761 ctgctacttc tgctaataaa agcaatgctt ggatcgcgtc tttatcgcga acaaaaggtt
    14821 taactaaata accataactt tcttcgaatc caaacataaa agtatgtgaa tggtcttctt
    14881 caaattgttg gattttttca gcaatgaatt taaaccctgt caacacattg aacatagtag
    14941 caccgtagtg ttccgcaatt gctgtaggca attcgctgga aacgattgat ttcaataccg
    15001 ctgcgttttc tggtaaagtg cctcttgatt gatgtgcttc caaaatatat tgagcaaaca
    15061 atgctccgat ttggttccca gtcaatactt cataagaacc atctggcaaa cgaaccgctg
    15121 cgcctaaacg gtctgcatca ggatctgttg caatcagcaa gtcagctccc tctttttctc
    15181 caagtcgtat agcatattca aaagctgaat gttcttctgg atttggcgat ttgaccgtag
    15241 tgaaatctgg atctgccaca gcttgttcgg gaactagtac gaattgttcg aatccagctt
    15301 gtttcaacgc acgttcgccc aacattttcc ctgttccatg aagtggcgtg tacacaagtt
    15361 tcaaatcttt ccccattgtt tcaaccaatt cacgatcaat cgtcactgct ttgatttctt
    15421 ctagataagc agcgtccact tcttctccga tgatcgtgat caacccgcta tgtttagctt
    15481 cttcgtcaga taatacttcg acttttagcg gattgctgac ttcacggaca tatttcgtca
    15541 atgcatctgc gtctgcagga ggcatttgtc cgccatcttc tccgtagact ttatatccat
    15601 tgtaagccgc tgggttgtga gatgcggtta ccatgattcc cgcaaacgtc ttcaaatgac
    15661 gaactgcaaa agaaagctct ggtgttggac gcagactttc gaatacataa gacgggatat
    15721 tgtgatgtgc cagtgttttg gctgcttcca ttgcaaattc tggtgactga tggcgtgagt
    15781 cataagcgat agcgacacct cggcgttttg tttcttcacc ttgtgtatcc atgaaacgtg
    15841 ctagtccttc tgttgcttgt cttaccgtat agatgttcat tcgattgatc ccaggtccta
    15901 agattccccg catgcctgca gtaccgaatt ccaacggtgc ataaaaagca tcttcaagtt
    15961 tttcaggatc ttcacccaga tcatttaatt gtttttttaa gttttcttct aaattttctt
    16021 catgtaccca ttgttcatac acttgttccc aagacatgaa aataacacct ctttctgaaa
    16081 tatggttctt aataagtata gcattcactt attagatatg aaagtatgag gaccaaaaaa
    16141 cgcttaaatc aagaaaggat tcttttatca agcatgattg caagtattca cataaatcgg
    16201 attcagtgga tttcacgcga aaaaaaagag taaaagaaca attgaaaccg ttctttcact
    16261 ctttttaaac ttatgctgtt gtttcttcta aagactccaa gtatttatac acttgttgtc
    16321 cagcaatacc gccgtcacca acagctgtag tgatttgtcg caaatctttt tcacgaacat
    16381 ctccgatggc aaaaacgcct ggcatattcg ttttcatttc gttgtctgtt ggaatccagc
    16441 cagcttcgtt cgtcaaacct gcttctctaa aaggtgcagt taatggatcc agtccaacat
    16501 agatgaatac tccgtctgct gctaaatcaa attcattgcc ggttttgaca ttacgtgctt
    16561 tcacacctgt cactaccatt tcgtttccaa cgatttcgtc aacgactgta tcccacataa
    16621 aggaaatttt ttcatttgca aatgcacggt cttggatgat cttttgtgca cgtaattcat
    16681 ctctacggtg gacgatcact acttcagaag caaattgtgt caaatagatg gcttcttcta
    16741 ctgctgagtc cccacccccg atgactacta gacgtttgtt acggaaaaac gcaccatcac
    16801 agactgcaca gtaagaaacg cctcgtccag caaattcttc ctcgccaggt acgcctaatt
    16861 tacggtggat acagcctgtt gcgataatga ctgtttttcc ttcgtaactt ttatcttcac
    16921 agatgacttc tttatggctg ccgtgatcct tgatatcttg aacgattcca taagcatttt
    16981 ctgtcccaaa tcttgagaca ctttcataca tcttataagc tagatcgggg cccatgatcg
    17041 aatcgaatcc aggataattt tcgatttctg ccgtattgtt catttggccg ccaggggcac
    17101 cttgttcgat catcaatacg gataagtttg aacgtgaagc atacaaagca gcagtcatcc
    17161 cagcaggacc tgcgccaata acgattacat catacatatg tagattctcc tttacttaat
    17221 caagtaagca tactttacag ccaatgcgaa aaaaagtcta ttgttctgct tgcgtttctc
    17281 gaatagcttt attatactcg aaaaatccgc tgaaaaacaa tagactttta taaatcattg
    17341 atcaattgtt cgaaagattt tctccatttg aatcaattac ttttttatac cagttgaatg
    17401 attttttctt tgaacgggct aatgtgccat ttccttggtt atcacgatcg acataaatga
    17461 atccgtacct tttcttcatc tcaccggtac cagctgatac taaatcgata catccccaag
    17521 tcgtatagcc taatagatcg actccgtcta gttctactgc atccttcatc gcctggatat
    17581 gcgctgccag gtaatcgatt cggtaatcat cttccacata accattttca tctggcgtat
    17641 cgactgcacc taagccgttt tctacaataa ataatggttt ttgataacga tcataaatat
    17701 cattcatcgt tattctcaag cctaatggat caatttgcca cccccattca cttgcttgca
    17761 gatatggatt tttgacagaa gcaaagatat ttcctgcagt ctgttccaag agttcgttgt
    17821 cggtagtcga aactcgtgaa gaataataag aaaaagagat aaaatcaaca gtatgttctt
    17881 tcagcaatgc ggcatcccct ggttccattt cgatctgaat gccatttcgc tccatttctt
    17941 tcaatgcata agcgggatat tctcctcgtg actggacatc aatgaagaaa taattttctc
    18001 gatctgattt tctagaagcc caaacatctt caggattgca agtgtatgga taatatgctc
    18061 ctgctgccag catacagcct actttgttct ccggatctac ttcatgagca atcttcgttg
    18121 cgatggcact tgcaaccaac tcatgatgtg ccgcttgata tttgatttgt tcttcatttt
    18181 ctccttcttc aaaatacagc cctgcgccca taaatggtgc atgaaggatc atattgatct
    18241 cattgaatgt cagccaatat ttgacaagtc ctttatagcg attgaagatg actcgacaca
    18301 gattttcata aaaaccaacg agttctctgg aacgccacgc accatattct ttgatcaaat
    18361 gcattggaca atcaaaatgc gtaatcgtca caagtggctc aattccgtgc ttttggcatt
    18421 ctttaaagac atcctcataa aatttcaagc cagcttcatt cggctctttc tcatccccca
    18481 ttggaaaaat acgactccag gcgatagaca ttcgataagt cttgaacccc atttctgcaa
    18541 acaaagcaat atcttcttta taacgatgat acatatcgat tgcaattttt gctggataaa
    18601 aatgatcctc atcaaattca aacatttttt tctttccggt gataacagga aaacggtctt
    18661 ttccgattgg cacaacatct acgtttgcta gtccgcgtcc accttcatca taagcgccct
    18721 cacattgatt ggctgctgta gcaccgcccc ataaaaaatc ttttctgaac cccattatac
    18781 ttcctccatt atatgtgtat tacctgataa ttctcttgcc agttcatctt gaacttcgat
    18841 tccttcttct tttaatcggc tgattgtttc cttgaattgc ggtaaatact gctggtgtgc
    18901 aataaacaac tcatccatga tccgttttgc tgtctttcct gatcgtataa gtggattgat
    18961 cgtaaacgcc tgtaaagctg tcccataatc accagtcaca gctgcttcga tcgtcagcaa
    19021 ttccatattc ttcattactt gcaaccagcc tctttcagca gcaggaagag aaccaaacgc
    19081 tacatttctc gctccttgtg cgccaacata ggcagtgact tctacaacac aatctgccga
    19141 caggtcagga acagctccat cattctttgt agatacaacg atctgtgttt ctttatttcc
    19201 atagattgaa gcaatcgttt cacaggcagc gtctgaataa taagcgccac ctcgtttttg
    19261 caattgttca ggtttatggt ctaattctgg atctttgtat aattcaaata gctctgcttc
    19321 tgtttctttc acttgctgcg ctcttgtacc aatcgtttga tattcttcta aagcatgttc
    19381 cagcatttct tcttcacgat agtaatagcg gtggtagcca caagggatca tgttcatttg
    19441 ttttaattgt tctttgaaaa acgggatatc aaagatattt ttcggtaatc cattatcttc
    19501 atcgtataaa cgatcaatca attctgccgt gcggtcattt cctttattat ctgctacttt
    19561 gtgccaatgg aaatgattta gaccggcaaa cttgtagatc agctcttctt ttttcttgcc
    19621 aagcattgct ggttctgtca tcatcgccat cactggcaca ttgcataatc caatcacttt
    19681 atcccatttg ccatatctga taactgcttc tgtcaccatc ccacttgggt tcgcgaaatt
    19741 gatcagccaa gcatttggac ataaacgctt catgtcctca acgattgcca aaacgactgg
    19801 aacggtacga aaagctttga atatcccgcc agcaccattt gtttcttgcc caatcatccc
    19861 ataataacta gggatccgct cgtctttgat tcgtgcatct aattgaccga cacgaaactg
    19921 agtcgtaaca aaatccgcat ctttcaatgc ttcttcccga tccagagttg catagatctt
    19981 gacttcatat ggagaagcat cccacatacg ctgagacatc tgactaacga tctcaagctt
    20041 ttcttttcct tcttctacat ctacgagcca gatttctcgt atcggtaatt cctcatatct
    20101 tttgataaat ccttccatca actcaggggt gtaactgctg cctccaccaa tcgtagcgat
    20161 tttgattcct tttgccatgt tctcactcct ttactttttt acactttcat tatctttttt
    20221 gtaaacaaaa caaacaatag aaatccgttt ctttccagta acatttacaa aagttactgt
    20281 tttctagtgg atttttgtaa atatcttgtc aaaaaaagcc tattttaagt tatatagtat
    20341 aaatccgttt acaaaacatt ttcaaaaaag ttataattta cgtaaaaaaa taagaagaag
    20401 gtatctacat gttattacgt gaaaaaatca aagaaatctc cttttctcct tcagaaaatg
    20461 aagtgatcca gtttctctta agcgattctc cagcacttgg cgaaatgacc atccaagcga
    20521 tagctgagcg atgttatgtc cacccgtcta cactcatccg tgtagcaaaa aaaatgggtt
    20581 ttgatggctg ggtcagtttt cgtaatgctt ttttagctga aacagcctat cttgaaggga
    20641 attttcaaga cgtagatgcg aatcttcctt tttccaccac agacggtatt atgacaatcg
    20701 caaataaaat ggcttcttta gaacagatga cgattcatga tacactttct ctcattcatc
    20761 atgaccaact gcaaaaagct aaatatttac tgctccaggc aaaaaaaatc gtgatcttcg
    20821 ccagtaactc gaatactttg atttctcaag atttcatgct gaaaatgaag cgcatcaaaa
    20881 tggatgtcac aattgtcacc acttttggtg aatcattcta tgaagcgtac aattgtacga
    20941 gcgatatgtg cgggattctg atttcttata cgggtgaaaa caatgtgatc cttcgtaccg
    21001 cagaaatatt gaaacaaaat gatgttccaa ttttagcttt gaccagtatc ggtgattcaa
    21061 cgctatctgc aatgagtaca gccgctttgc gacttacgac acgcgagcga ctgtattcaa
    21121 aaattggtaa ttttacgatc aatacatcaa tttgttatct tctagacgtg ttatatagtt
    21181 gtgtttttgc agaaaattat caacagaatt tagtccatct aatttctgtc ggtcaaaaat
    21241 tcgataaacg ccctatcagc tcagccatca tgaaagagcc tttcaatttt gaaaataaag
    21301 aagtggaata aaaagaatag ttaagcctag tccattcttc acctaaccgt tcaggtcagt
    21361 gcggtgataa gtgcatcgtc tggcccgacc gtctcccctt ggttttccaa aatatccaaa
    21421 taatccgtgt aattggtgac gatcacaggt gtttctaaac tgtatccttc cttttcgatt
    21481 ttctttttgt cgaagcgtag caacagatcg ccttgtctca ctctttctcc ttgctgcact
    21541 aagctttcaa aatatttccc ttccaactgc acagtatcca atccgacatg aatcagcaat
    21601 tccagccctg tttcagaaac cattccgatt gcatgtttcg tcgggaacag ggtcataact
    21661 gttccgtcaa aaggggcacg tacttctcct ttttcagggt agattaagat tcctcgacct
    21721 agtgttcctt gtgcaaaagc tgcatccttc gctgcattta gtggagcgat ttgtccttgt
    21781 atcggtgttt ttacaatttc tttacctgat tttttctgta tagcatctgt ttcacctgct
    21841 tcatccttcc aaaagaaaaa agtcagcgaa aacccgatta ccgaagcaat agcaatgccg
    21901 ataaacgctt gaaacatacc actggcgtct gtttccgtga tgtagtttac caccccaaaa
    21961 atccctaatc cgcccattat gtagctgatt gttccagatg ccatcaaata gattcctgaa
    22021 acagcaccac caatcatcga gtaaataaat ggcttcttct tcggtaaggt gattccataa
    22081 atagccggtt ctgttacgcc gaagattcct gaaatcacag ctggcatgca aagcgccttc
    22141 attttttgat ccttgaactt gaaatacatc gccaatacca ctgctgtctg tgcaaaactc
    22201 gcgccataaa cgcctactaa catctgactc cacccatttt gcgctagctg cataatcgca
    22261 agagggataa tactccaatg aagtccgaaa atcaccagta cttgccaaag aaaccctaga
    22321 actgcaccat acacagctgg agaaaagtcc atcaatgctt ggaatcccgt gcttaataga
    22381 tctgtcagta tactgacaat cggaccgata atcaaaaagc cagcaggaag tgcgattaat
    22441 aacacagaaa aagaaaccaa aaaggtctgg acgactgcag gaatccattt cttggcaatt
    22501 ttttggactt gtccggcaaa tgcgataatg aagataacag gtacgacgct actagtataa
    22561 ctgctgccca cccatgggat acccaaaaat gtttcataag ccggaagacc cagcaagcta
    22621 taaggcgcag gactgccatc agggaaacca ctttgtagtg ctgctccttg tacagtcgga
    22681 taacaaagtg ctgcaccaat cacgagcccc accatcggat tcagatgaaa ttttttcgct
    22741 gctgtgtacc ctaagatcac tggcatgaaa taaaaaattg catcccctat cccattcagc
    22801 atgatgtacg tacccgatcc ttcagtataa aatttgagaa acaagaacaa agcatttaat
    22861 cctttgacca ttcccgctgc agccaaagca cctaaaaaag gctggaaaca gccacttaat
    22921 atgtcgatta atcgattgaa cagattacta cttgaagaaa cctcttcttc tgcttcatcg
    22981 gaaatcccgg ctactgtcag tacttctgca tagacatctg gcacatgatt cccgattaca
    23041 acttgatatt gcccgccgct tttcatgatg gtgactatcc cttccatctt tttcaaaaca
    23101 tcatcctttg ctttattttc ctcctttagt ttgaaacgaa gtcgcgtcac acagtgtgtc
    23161 aagctacgga tattttcttt tcctccgata ttctttacga tgttttctgc taattcctgg
    23221 tattttccca tttctattcc ctccaattaa ttagtggaag gtttagccaa ctgaatgtca
    23281 ctacccttat ttcatacgtt cttgttaatt tgtcctcctt ttttatttat ttacaacgat
    23341 tctcatgcac taaacgcgca gtatggatcg ttaaatacat tttttcatcc gtggacatct
    23401 ggtagtcgaa agccccggtt aaaaagtctg ctattttctc aacgcaacca aacgtatcct
    23461 tatatttttt ttgaataact tggaacaatt cctcagaaac ttctccatct tctgatttcg
    23521 ctccatctag gacacgtgtc agaaaaaaac gcaggtgtgt gacgaatcga aaaaagtgga
    23581 ctgaatcttc atcaaatgta atcttatagt aatagcggac gatatttaaa atatcctgta
    23641 ttgttgtggt aaacaggtag gtattgtctt gctggctttg aatgccttgt gcattgacta
    23701 aatgcaatgc gataaatccg gcttcgtctt ctgataactt gatgtggtat ttatccgaga
    23761 ttttcttcac tgtttttttc ccaatggcat actctttagg aaacagttgt ttgatatcat
    23821 acagcaatac atttggcaca aagatcccca ttttttgacg ttcgatagct gtatacaagt
    23881 gatccgtcaa tgaaatatac acagaatcat ttaaatggac ttgcagagcc tcttttgtat
    23941 attcaatgat ttcacaagaa atttctaagt actcaagagg aatcgcttgt gccaattctt
    24001 ggaactgttg tgaaagtccg tcatttgtca actgaaattt tttgtcgatg catgagtcaa
    24061 gaatcgggtc acccaccttc tttttgaatg ccaatccttt tcccatcaca atcatttccc
    24121 gatctctttc atcccttgtt attacgacgt tgttattcag tactttctca atcagcatgt
    24181 tttgctcctt tccatgatat atagggctgt atccaaaaca aaaagaaaaa cccaaaaagc
    24241 cgtccatgaa accatgggag actcatcagg tttagcttgc atcaggcaat cactatccaa
    24301 gttgtatcgt tttctttata ttatcgaaag caaacgattt tgtcaacgct ttcttagggg
    24361 ctattaggca cttctgacta gctgacgtcg tcttttttaa atctggtaac tacgacacta
    24421 actctcacag atgaaaaata tgggaagcta tgttttattt tcactctagt gcttaggtca
    24481 aaatgctact gtcacaacat cttttatata ccactacttt gcagtttgta catatctgca
    24541 tacaaaccat tttgcgctag aagtgtttca tgattcccgc gttctactat atgacctttg
    24601 tctaaaacta aaatcaattc tgcatctcga atcgttgaca gccgatgggc aatcgcaatc
    24661 gttgtccgtc cttgtcgcat tttcgccaat ccttcttgga tcaatccttc tgtttcagta
    24721 tcgatatttg ctgttgcttc atccaatact agaattttag gatcagtcac gattgttcgc
    24781 gcaaaagtga tcagctgtcg ttgtccacta gaatagctgg caccatgttc gatcactttt
    24841 gagtgatatc cttttggtaa ttcatcgatg aatttgtttg cttgaacaaa ctcagccgca
    24901 tggcgtatct gttcgtctgt gatagctgga ttcatcatcc gaatatttcc tgcgatatcc
    24961 ccataaaaca agaaagcatc ttgcaagacc agccccattt tcttacgtaa ctcttccatt
    25021 ggatattctc gaatgtcatg atcatcaatc aatatctgac cttcataaaa ttcgtaaaac
    25081 cgcatcaaca cattgatgat cgagcttttc ccacttccgg tgtgtcccac taatgcaacg
    25141 gtttctcccg gattagcaac aaaagagata ttgtttaata cattgtgctc tccatcataa
    25201 gaaaagctta cattgcgaaa ctcaatctta cctgaagtaa tcatttgatc tgctccaggg
    25261 ttttgttgtg gtgcatattc ttccgtatcc ataatcttca agatacgact accagcaacc
    25321 atcccatctg tgaagatgct caaaaagtcc atcatttgag acattggatt aaaaaatccc
    25381 tggacataag tcgtaaatgc atagatcagt ccaacttcta cgggagaatg caacgcatcg
    25441 atcccaaata aagtcaacgc caacgcaatc gccaatgcat atagaaaatt gatgatcgga
    25501 cttaacagaa tcgaattcgt tttgatcatc gcatagcgcg tgtctaaata ctcattgttc
    25561 acttgttcaa attctttagc taaacgagct tcttggcgaa actgctggat aatacgcatg
    25621 ccggaaatcg attcattcaa ttttgtattc agctgactta atttttcccg catatttcgg
    25681 taaatacgag aactaaattt ctggtaatac cagatgacaa ttcctaaaat cggcaagaac
    25741 accaaagtcc acaaggcaat ttctccattg atttgaaaca tggcaatgaa tgaagaaacg
    25801 actgcaaaga tcccagtcaa taccatcaaa aagacgtacc aaaattcaaa tagcgtttct
    25861 gtgtcattcg tcactcgaga aacggttgat cctgccggtg tctgatcaaa ataacgcata
    25921 cctagtgtat gcagcttttc aaataatttt accctaatat actgataggt cttcaatgaa
    25981 gccatggaat acaaatacca ttggaaaaac caaatgatac tttttactag gactccaaat
    26041 aagtacatac cagcaaaaaa caaaataact tgtgtcgtag ccgactgttt agccagatga
    26101 tcatccataa aagtttggat gatccttggc aataggacat tgatcacaga cagagcaaac
    26161 gcaaataaga tagcaacgat gaacgttgtt ctaaaaggtt tggcgaactt catcagtcgt
    26221 ttgatgatct ttttctgttc tttaagtgga atcgattttg tccattccga ttgataattt
    26281 tcatccatca ggcctcgcct ccttctatct tcgcttctaa ttgctgtttc tcccacattt
    26341 gttcatacca gccgcctagt gcaagcagct catgatgggt tcctcgttca atgattttcc
    26401 cttgatcgac aacaatgatt tcttttgcat gcatcacgct acttaaacgg tgagctgcaa
    26461 tgatagttgt tttctctttt cttatttctt ttaaattatg caagatagct tcttctgttt
    26521 tggcatctac tgcagaaagt gcatcatcta atattaataa ttcaggattt ttgatcaatg
    26581 ctcgagcaat cgaaatcctt tgtttctgtc cgccagataa agagactcca cgttctccaa
    26641 ctaaggtatc ataacctttt ggtaattcct tgatttcatt gttgataaat gctaaagaag
    26701 ccgcatgctc tacttcttct tctgaaagtt ttggattaga aaaacggata ttatctcgaa
    26761 tggtcatcga aaacaagaag tgatcctgag gcacatagcc gattgatcct aataaagcat
    26821 tcaatgaata ttctttgatc gaacgtccgc caaattggat tttcccttga taatcatcgt
    26881 attcacgcat cagtaatttg atgatcgttg tttttcccgc accagttttc ccaacaatac
    26941 ctaatgtttc tccttcttgg attgcaaact tgatttgttc taatgctggt gattcttctt
    27001 tcggataatt aaaagaggaa atagctacat tcagctcgcc ttttaccggg gtctgcactg
    27061 cacccagttg ttccacgata tgcgtttttt catgcaaaag ttcattgacg cgatcataag
    27121 aagcatttcc tctttccaat acgttgaaca atcgaccaat cgcaaacatc ggccaaacaa
    27181 gcataccgat ataactaata aatgagacca tctgcccgat cgagatcgtg ccttccaaga
    27241 catactttcc acctaaaata attgttgcaa cataagacag accgataatc aaggtaatga
    27301 atggatcaaa taaggagtct agaaaattga ctcgtttgtt tttaataatt gcatcttcaa
    27361 tcttttcttc aaaatccgct agatcttctt tttcttgtcc aaatgtttta atgactttga
    27421 tcccagtgat actttcttgt gtcttatcat tgatactaga aaaagcttct tgcgaatcac
    27481 gaaaagcatc atggagtttc gaccccagca ctcgtgaagt gacggccagc aaaggcagag
    27541 gaatcagcgc aatcagtgtt aagcgccaat caataaacaa aatcatcaca atgatcgttg
    27601 ttccgcccgt aatcactgaa tctgcaaagg tcaagatacc agctcctgct acattctgga
    27661 tcgcattcaa atcattcgtt gcatgagcca tcaaatcccc agtccgatat ttttggtaaa
    27721 agagattgtc catttttgta aaatgtttga ataactgctg ccgaagttct ttctccaacc
    27781 gagctgcact tccccaaata ttcgtccgcc agatataacg aaaaagatat tgtaagaaag
    27841 cagcgataat caataggaag atccacccga aaatgatctt tactgataaa tttttatcgg
    27901 caatctcatc aatgatgatc ccaatcactt ttggaggaac taactgtacc aaggccactg
    27961 cgaatagcga gaaaacccca attaaataat gtttcttttc ctgacgaaaa aaccagccta
    28021 actttctaaa aatcgacatt ttactcctcc tttgtcttta tcaagagcct aggattgtct
    28081 gtgcttgtct ttttgctgaa taatctgaat agtctaacaa attacaaaat aaaaaacgga
    28141 ctgaaaaaat cagcccgtaa aaagtcgttg ggtcagaacc tattttttcc cttggttctt
    28201 catttgctgc atcatctggc gaattttctt ctcagatggt ttttgtccca ttgacatcat
    28261 cattgatcgc aacatgtcct cattaacggg aggatttttt tctaaatagt ctttcatata
    28321 tttacgcgct aggaaaaagc cacctactgc gccgattagc aaagcaataa tagcaataag
    28381 tacgacaata cctgttgata acatataaat ctctcctttc tatttccgaa ttgctctcaa
    28441 tgacttattt tactaaagtt tattgaaaaa agaaaggcgt attctttagt ttcatgcaaa
    28501 aaatagtggt ttttttagag gagaacaaaa tttctttcgt catctaacaa gacgcgccac
    28561 gaaaataaat taggcatacc gaatattttt ctttaatttt ttctttttga ggtgtagaat
    28621 gtaatcgtag ataaatagga aaggtggttt tttcttgaat aatcaatcca acaaacaatt
    28681 tcataagcat cgacttattg aacatacaaa tggtttatct ttagctgaag taaatggaac
    28741 agttgatgta ccaaagggga aaagtttttt taaaacactt cttgcttact ctggaccagg
    28801 tgcattagta gcagttggtt atatggatcc aggtaactgg tccacttcga tcactggtgg
    28861 acaaaatttc caatatttat tgatgtcagt tattttgatg tctagtctga ttgctatgct
    28921 tttacagtat atggcagcaa aattaggaat cgtgacccaa atggatttgg cccaagcaat
    28981 ccgagcacgc acaagtaaga cattgggtgt cattttatgg atcttgactg aattagccat
    29041 tatggcaaca gacatcgcag aagtcattgg tgcagcaatc gccctctact tactttttga
    29101 tattccattg gtgattgccg tctttattac tgtattagat gttttcgttc tcttactact
    29161 gacaaaagtc gggtttcgta agatcgaagc actggttgtc tgcttaattt tcgtcatttt
    29221 attcgttttt gtctatcaag ttggcttgtc taacccagat tggcacagtt tatttgctgg
    29281 ctttatccct aacagtcata cattctcaga ctcaccggtc atcggcggcg aaactccgct
    29341 gactggagct ttagggatta ttggtgcaac agtcatgccg cataacttat atcttcattc
    29401 agcagtttct caaactcgga agattgatca ccaagacgaa gaagatgtag cacaagctgt
    29461 acgtttttct acttgggact ctaatatcca attgtcgatg gcttttctag tcaatgcact
    29521 gctattgatc atgggtgtcg ctgtcttcaa aaccggttct gtccaagatc cttccttttt
    29581 tggtctgtat gaagccttat ctgatccatc agctatgagc aatggtatct tgattgctgt
    29641 agcaaaatct ggtatcttat ccactttatt tgctgtagca cttcttgctt ctggccagaa
    29701 ctctactatt actggtacgt tgaccggtca agtcatcatg gaaggcttca tccatatgcg
    29761 tatcccgatt tggctaagaa gactggtcac acgattgctt tctgtgattc ctgtattgat
    29821 ttgtgttttg tttacaagta caaaaggaac gatcgaagaa cataccgctt tgaataactt
    29881 gatgaatgaa tcccaggtgt tcttggcttt tgcgttgccg ttttcgatga tccctttact
    29941 gatgatgacc aacagccaag cggagatggg tagccgattt aaaaattcat tcatcgtaaa
    30001 acttcttggc tggttctctg tgattagtct aacttacttg aacttacgag gattaccagg
    30061 acagatcgaa agtttctttg gtgaacaagc cacttctgct caactagcat tggctgatca
    30121 catcgcttat gtaatcattg ttcttgtcct tctcctgttg gcatggacga ttggtgattt
    30181 atataaagga aacaaaaaat atgaacagcg tttgcaggaa acggtagaag aaatcgaata
    30241 gaaactgatt tttccacaca aagacccttg atagttaggt taaaaatcta gctaccaagg
    30301 gtctttttat ttagaagata aagccttttt cagatttaat ttactgaaaa ctagcatgct
    30361 tgttactacg atgaattgcg ttaatggcac gcctgcgcca gtgtagacac ttaaaaaata
    30421 atcctttttt tctggcgcat aagaacaaaa ccacgagaca ccgaaaagaa aaaccaattg
    30481 tgtcagtatt aatccggtga ccacaatcaa agaggaacta taataggcac gatcagcttt
    30541 tgcaaatacg gttcctagta tcataagtaa tatccctgct attgaagcaa tcagcacggg
    30601 aatagccaga acttggtaaa tttttatgat gacattcgcg acttttgctg attttgttaa
    30661 ttggaaatta ggtgttctcg gttcattact atcgatccaa ttctccatta gcggaaggtt
    30721 taataattct tgagcctgtt tgacttgttc ttgcgttccg aaactataat ttcctccttg
    30781 atggaaatct ttatatcgcc atgcataagc gtatcctgat tgaaggaaat cgaatacgat
    30841 tggcagatca ctcatcgtct ttccatctcc tgatcccatc agatagaact cttttttctt
    30901 tttgatggtt cccttgtgat aggcttcttc taattcttgg ttgacttttt tccaaaaatc
    30961 attggtttct tttgcattgt tttggtaata accagattcg cttaccacat ctcgcaatgc
    31021 ccaaaagatg atatctccgg gtaattcttt tacttttcca ccttgagtcc acgcgtgagt
    31081 cgtatataat tcgtcaatac gggtagaaac agtatggaat gtaggagatg cggctaatgc
    31141 tttatttagt gcagcatgtg agacccatat ctcactgttt tctttattca agttcgtttc
    31201 atcatctatt cggatcagtt gtttcatcaa acgtccaaat tctccactgg aacggtcatt
    31261 gatggttgca ataccgtatg ttgtctcatt tttatattcg atccactgat agacgatgga
    31321 aaagccaact ataggaagta aaaacaatga aagtttcagc cattcccgtt tcgagagaag
    31381 aaagagtcgt ttttttaact tctttacttc tttgaaagaa aagtcttgcc ctagcaagat
    31441 ctggacgaaa ctgataccca aagctactac agtaaaagga agaagccaga tagaatcttc
    31501 gcgaatgaac caaaagaaag gaaaagcgac agaaagccct aaaaaccatg gcagcaattt
    31561 tctgctagaa ccgtatttgc ggtaataaat agctagtaaa caagcgataa tgatctcaac
    31621 agccggaatc acgagggcat tacgatatgt tcgagtggaa tattcatgtg taaaactaat
    31681 cggagaaaac aaaaaataaa aatagatact taaaagaaga tacttgttct tcacgatcgg
    31741 tttaaacgcg agtgcaacca atatactggc aaaaatactg aacatgccga acaaaacagc
    31801 ataagaaaga tgcagtttat gtgcaagtac taaaaataag ctgtaggaga ttcctttgga
    31861 aagtgttgta gtcgtatact cccctagcca tttaccgtcc aaaatatttt gagcatagcg
    31921 aatcagcagc tggtcatcat aggttgccga catgtctgtt ccatagattg ctttactata
    31981 taaatacaaa cgaataattg taaataatag ggctatgcca agaataaagt atgtatgttt
    32041 cttttttagt tggttgatca agggttttaa agtgttcagc atcttttcgt ccttccaatc
    32101 acgttttgcc acttgcttgt gaaacttttc gtttttttac ttttctaaca gtataccttg
    32161 tttgtctaaa tttaaaaaga ggggggagaa gatgcatgat gaaaaagact gcaaaaagta
    32221 ctcctttgtt tcttaaacaa aaaaggacaa ggcaatgtgc ctggtccttt tttgctgctg
    32281 tcagatagaa aatcttagag tatcacttct tctgctaata actcaggaaa cacttctgga
    32341 tcgaatattt gtgctttgaa catggcgatt tcttttccat atggtgcgta agctttcttt
    32401 ttatctttgc cgacataggg agtttccaag attttcgaaa tattgtcaaa cattggatca
    32461 tggacgatct tattcagcgt gtcgaatccg attgttccaa aaccaatatt ggcgtgccgg
    32521 tctttatgcg aaccttgcgg atttttagaa tcattgatat ggagtacttt aagccgatct
    32581 aacccgatga tcttatcaaa ctcttccatt acacctgaaa agtcttcttt aatattataa
    32641 ccggcatcat tcgtatgaca ggtgtcaaaa gtaacggata atttttcatt taattttact
    32701 ccatcgatga tttgcgctaa ttcctcaaat gttcgaccga tttccgtacc tttacctgcc
    32761 attgtctcca aagcgatttg tgccgtctgt tcttttgtca aaacttcatt caagccttca
    32821 ataattctag caattccggc ttctgttcct gcccctacat gagcacctgg gtgaagtgta
    32881 atttgagtag cgcctaaagc ttccgcacga acaatctctt ctctcagaaa ttggacggca
    32941 aaaggaaaca tttctggttt gatcgtattc cccaaattaa tgatataagg ggcatgaacg
    33001 acgatatttg ttagaccgtt ttctgccatg tacgcttttc cggcatcaat attcatctct
    33061 tcgatggctt ttcttctagt gttttgaggg gcgcctgtat agatcataaa agtcgaagat
    33121 ccataactgg ctgcttctgc tgctgctcct aacagcattt tctttccgct catgctgacg
    33181 tgtgagccta ataacatgga tggattcctc cttgaaaggc aattgttact aacaattcct
    33241 atatattggt aagatgatat acaaagaaaa tgattgattt ttctttgccc tgttctccat
    33301 agtaactgaa attttctcta aagaaaagct taagaactct tttataataa agatcatttt
    33361 ctcacgtttt aactctttta aaaaagaaat tcctgccaaa aacagccttg tctgtttttt
    33421 tgttctatta tttgctataa ttagcgaaat aaaaccatta gttgaggtga cccttttgcc
    33481 acgcaaaaat actcgaaaaa aacagaatag aagaaaaaaa gaaaaatggt ttgttcctaa
    33541 gattattttt agagtttttc aatcattgac tgtttttatt actgttcttc ttttgatgtt
    33601 cgcagctcta ggtattggaa taggcgctgg ctattttgcc tatctcgtcg aagacacaca
    33661 attgccgact aaaaaagcac tgcagacaga actaggaaac attacagaaa cgtcaaagat
    33721 tgtttatgca gataatacag agatatcaaa aatccagaca gatctgatgc gcacgactat
    33781 ttcatctgat aagatttcac ctttattgaa aactgcaatt atcagcacag aggatgaata
    33841 cttcgataaa caccaaggtt acgttcctaa agctgtttta cgagcattag tatctgaagc
    33901 tactggtatt ggctcttctg gtggatcaac tttgacacag caattagtca aacagcagat
    33961 ccttacagat gaaacaacat tcaaacgtaa agcaaacgag atcattcttt ctgcacaagt
    34021 agaaaaatac ttttcaaaag atgagatcat tgctacgtat ttgaatgtct caccatttgg
    34081 tcgtaataat aagggacaaa acattgctgg agtccaggaa gctgcaaaag gaatctttgg
    34141 tgtagatgca aaagatgtga cgctgccgca agctgcttat atcgctggat taccccaaag
    34201 cccgatcacg tatagtccat acacgaacac aggcgcgcta aaagaagatc tttctgccgg
    34261 ccttgccaga aaagattttg ttttattcag tatgtatcgt gaaggccaaa ttacgaaaga
    34321 acaatacgaa gaagcaaaag cctatgacct tacaaaagac tttctaccac aacaaatcgc
    34381 agaacagact gacagagaat tcttgtatta tactgtgatg aatgaagcaa caagaatcat
    34441 tgcacaacaa ttggctgaaa aagacaacgc tgatatgtct gattcatcgg tcagtgacgc
    34501 ttattatcaa aaggcacagc aaacgatcca aaataaagga tatacaatcc attcgacaat
    34561 cgataaagat gtctatgctg cattgcaaaa tggcgttgaa aattatggat acatgttaga
    34621 tgatggtgct ggcagtcaag tagaaaccgg aaatgtattg atggataaca gaactggccg
    34681 catctacgga ttcgttggcg gacggaatta cagtcagaat caaaataacc atgccttcga
    34741 tacagaacgt caagctggct catcaatcaa accagttctt gtttatggac ctgcaatcga
    34801 catggggctt atcggatcag aatcccgtgt atcagattat gcaacaactt ggcaagaagg
    34861 agaaaatgct ggcgagaaaa tcgtcaatgc tactaacgaa ggatcgaaca ccttccaaac
    34921 cgtccgtgag tcactagaat ggtccaacaa tatcccggct tatcacttat atcaagatgt
    34981 gttgaattcc ggtggatcga aacaatatgc ttacgagcac tacttggcaa agatgaacta
    35041 cccggcaaat gacaattggg gcgttgaatc tgctccttta ggtacagtag atgtcacgac
    35101 gcttcaacag accaacggat ttcaggcttt agcaaacggc ggcgtctatg aagaaggcta
    35161 tatcatcgat tccatcacag ataacgcagg aaatgtaatt tataaacacg aaagcaactc
    35221 tgtccggatc tattcggaag caacggcatc gatcatgaat gacatgatgc gtagtgtgat
    35281 caatgcaaaa atcactacac cattcaaaga tgccatctca agcttaaacg gaaatctagg
    35341 aaaagcagat tgggtcggaa aaactggttc taccaatgaa taccgagatt catggctaat
    35401 tgtctctact ccgtctatta ccatcagtag ctgggcaggg cacgatgaca atactggaat
    35461 ggacagcaaa gcaaggatac gttcggctaa ttatcttgcc aatctgatca atcaagctta
    35521 ccaagcaaaa cctgacattt ttggcactga tgagaaattc gaattatcat ctgatgtgat
    35581 gaagaaaaaa gtatctggat ttactggtca aacacctgga aaagttactg tcaataaaaa
    35641 atccatccaa acaccaggaa aaacagttga atcgctatgg gcgaaaaatg gaccgaagaa
    35701 aagcgccttt aaatttggcg ttggcggtac cgatgaaaac tatacagatt actggaacac
    35761 cgcttcagct tatgcaagag cgaatcaagc aactaaagaa tcagatgaga aagatgattg
    35821 atttaataga atacacagta ataagggatt gtgacaatag tattgtcaca gtcccttatt
    35881 tttttgatgg tggtgaacaa aatgcagcat ctatacacgg attgttttat atacgataaa
    35941 tgtaatttca accactttct ctctttttta agacacaaaa aaaggattat aacaaaattt
    36001 tgtcataacc ccttttccca aataaacggt gttctcctgc caactccgaa tcacgagtca
    36061 caatattcat caaacatgag atgctgtttt ttgaaattgc tccttgtaac gcagagttaa
    36121 acggcaggca cacaacctct gaatggttgt ccttttatta ttttgtagat cctttttctt
    36181 cgattccata aggcaagata atcgtttttt cttcgacttc ttctttattc atcattttcg
    36241 tcaataggcg catagatacc gcccctaaat cgtataatgg ttgtgtgata cttgttaaac
    36301 gaggacgagc tacttctgtc agtagtgaat tgttacttgt gatgatttcg aattcttccg
    36361 gtactttcac gccacggtct aataaaccat ccaaaatacc gatggctaat tcatcatctg
    36421 aaacatagac agctgttgca ccgctattat ggatccgatc gactagagat agaccatctt
    36481 tgaagttgta ttgtgcttca aagatcaatc cttcgctata tggtaggtta ttttcgctta
    36541 atgcttcttt atagcctttc agacgatttt gtccattgat gggatcgatc aacgcaccac
    36601 tgacaaaagc gattttttta ttgccgcttt ttgccaattt gtttactgca tcttttgttg
    36661 cggatacata atcaatgttt acgctaccta cttgttcatc tggatcaata gagccagcta
    36721 atacaacagg agtttttgaa cgtgaaaatt ctccacggat ttcgtctgtg atatggtgac
    36781 ccatgaagat cacgccgtcc acttgcttag ccagtaagtt attcaataca ttgacttctt
    36841 tttggtcgtt gccatctgaa tttgctaaga taatattgta tttgtacatt gttgccacat
    36901 catcgatacc acgtgctaaa gaagcaaaga acatattgct gacatcaggg atgattacac
    36961 caactgttgt tgttttctta cttgccaagc cacgcgcaac tgcgtttgga cgataatcca
    37021 agcgatcgat aacttccaag actttttttc ttgttgctgg tttaacgttt ggattgccat
    37081 ttacgacacg tgaaacagta gccatcgaaa catttgcctc tctcgctaca tcatagatag
    37141 tgattgtttg cttttccatt tgtgttctcc tattcatatt ttatatgttt tctgaaaata
    37201 cgtcttacat ttctaaaata gaatatcaaa taatctcaag aattgcaacc gttttatctc
    37261 tgttttcatg aaaattttta cttttttcag tttttagaac gttggtcttt taataaatca
    37321 gtggtacaat tattgaatac aaaattaatt tagaaagtag gttgccaaat gaataacgta
    37381 aaaatcaatg aactacgtca atggatggca caacaccaag tcgaattggc ttatatcagc
    37441 gaccctggcc acatcgctta cttttccgga tacgaaagtg atcctcatga gcgtgtacta
    37501 gctcttttta tccctcttga acaagatcct ttccttttca ctcctgcttt ggaagttgaa
    37561 gatgctcaaa acagtagttg ggcgtatgat gtccgtggct atttagacag cgaaaaccct
    37621 tgggagatca tcggaaaaga acttcgtgct cgctatggtc agcctggcaa tgtagggatt
    37681 gaaaagaacg ccttgactgt cgagcgcttc gatgctatct ctgatatctt gacgggaacg
    37741 gattcttaca ctgatctaac ttccatcatc caacgtctac aactgatcaa aactctagag
    37801 gaaaaagaca aactgatcga agctggtaaa tgggccgatg ttgcatttga gattggcttt
    37861 aaagcagtga aagaaggcgt gactgaacaa gcgatcattg cagaaattga ataccaattg
    37921 aaaaaacaag gtgtttcaca aatgtctttc gacacattag tccttgcagg agcaaatgct
    37981 gcaagccctc atggtacacc aggaaatacg aagatttcac cgaatgaact tgtgttattc
    38041 gatcttggcg ttgtttggaa tggctattgc agtgatgcta ctcgtacaat tgcttatcaa
    38101 aaaccaaccg acttccaaga aaaaatctac aacatcactc ttgaagcaca gcttgccgca
    38161 caagaagccg tccgtccagg tgtgacagca ggtgaacttg atcaaatcgc acgaaacgtg
    38221 atcaacagct atggctacgg cgaatatttc aatcaccgtt taggtcacgg gatcggaaca
    38281 accgtccacg aattcccttc ccttgtagaa ggaaatgact tagtaatcga agaagggatg
    38341 tgcttctctc ttgaaccagg aatctatatt cctgaaaaag taggggtacg tatcgaagac
    38401 tgtgtatatg tgacaagcga tggctgtgtg ccattcacga ctacaccaaa agaattactt
    38461 gttttagaaa aataagagta aaaaaggtga gagctagtcc gctcccacct ttttattcta
    38521 taaatttgtg attttagtga tttgtagatg aatctgtcat tgtatctttt atttcttttt
    38581 tagcttcttt cgcatcttct tttgccattt tcatcatttc ttttgagtca tctgcaactg
    38641 gttttgcttc tgacattcct tcattgacag tatctcctgc tttaccagca gcgtctttta
    38701 catcaatcat gatatcttct gaagtatctt tagcaatact tcctaattca tctgcaggtt
    38761 ttttcatatc ttctgccgtt tttttgaaac gattagataa gtcagctgat tgttctttaa
    38821 gatttaacaa gatatcgtca gattcacttc ctgcttcatc tgctgattca cttacttttt
    38881 gtttgacact acctgctaga tcacctgctt gttgagaaag atcttgcgct ttttcttttg
    38941 caatacctgt taactcagtc gatttttctt tcgccatatc tgtgtaatct gaagccatat
    39001 ccatcaaatc atccgcttgg gcagctaatt catcccgaag ttctttacca gattttggtg
    39061 ctaacaataa cgcggcgatt gctgcggctg tgcctccgac tactgcacct aataaaaatc
    39121 cacctttttt agccattttt attttcctcc tgtcgtttca gtatgttttt tgtttttaaa
    39181 aaatttcatc gctgtcccac cgacttttcc ggcaaccgtc gctttagctg tcgttttacc
    39241 gattccgccg actttcgtcg cgatgttttt actagaatga ttaagttctg atacactttc
    39301 acttaaatca gcaactgctg tgaacaatgg atcgatcgtt gcgacttttc cattgatatc
    39361 caagagcagt tcattacttt tgaccagtaa gccttctact tgtctagaca aaagatctac
    39421 gtcttttgtg acgatttcga tcgtcgtatt tgcttctgct acagtctgat ctactttttc
    39481 taaagtttta gaaacttgca acaacacacg aacgataaaa acgacaagta tcgcaaaggc
    39541 gattgctgcg atcaatcctg caatttctcc tcctgacatg atcaaactcc cttcttgtct
    39601 ctcttttcta taaggatagc attttcgtgt tttttaaaca aataaaaacg agcttcaact
    39661 actttttatt caattagcag ctgaagctcg ttagaaaaaa gggttatttt ttcttttctt
    39721 ctttgatttc tgttattcct tttggattat gatcgatctt gcttccttct gcttctaatg
    39781 ttttacctaa agacaggatg tactcacgta aaggtgcacc tacttctgga tgtgttagac
    39841 catattcaat acttgttttc ataaaaccaa atttgtcacc gacatcgtaa cgtttacctg
    39901 tgaatttacg ggcaaatacg cgttgtgttt tattcaatgt atcgattgcg tcagttagtt
    39961 ggatttcatt tccggctcct ggttgttgct cggacaatac atcaaaaatt tctggagtca
    40021 ataagtaacg tccaataata gctaaatcac ttggtgcttt gcttggatct ggtttttcaa
    40081 caaagttttt gacattgtat aacccatctt ccaatacttc tcctggattg ataattccgt
    40141 attttgaagt ttcatcatga ggaacttgca taacggcgat cgtagaagca tgagtacgtt
    40201 cgtaatcatc gattaattgc tgtgtcaatg gtacttcgtc ttccattata tcatcgccta
    40261 gcataacgac aaatggttca tttccaataa aggctcttgc ttgaagaacg gcatgtccta
    40321 aaccctttgg atgagattga cggatgaaat gcaagttgac atctgtcgtt tcttctacta
    40381 atttcaataa ttcggtcttt cctttttcac ttaggtttgt ttctaattca atatttgaat
    40441 caaagtgatc ttcgattggt cgtttagctt ttcctgtaac gatcaagatg tcttcgatac
    40501 ctgatttcaa cgcttcttca acgatgaact ggattgttgg tttatcaaca attggcaaca
    40561 tttcctttgc catagctttt gttgctggta aaaatcttgt tcctaatcct gctgctggaa
    40621 taactgcttt tttaactttc atatacattc gctccttcaa aaaattgtta atgagaattc
    40681 attttctttt tttccatcac gtaacatgat ttcttttgcg gctgttttga tttctttttg
    40741 ttcatacagc acttcataga ttgtttgagt gatgggcatt tcgatttcca tcatttgggc
    40801 tagttccatc gctgcttggg tagtattcac accttcaacg accattccca tattggctag
    40861 cacctctt
//
LOCUS       DACGLI010000025        39854 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.026, whole genome shotgun sequence.
ACCESSION   DACGLI010000025 DACGLI010000000
VERSION     DACGLI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.026"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            1..369
                     /locus_tag="IXT22_001371"
                     /pseudo
     CDS             1..369
                     /locus_tag="IXT22_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(495..1574)
                     /locus_tag="IXT22_001372"
     CDS             complement(495..1574)
                     /locus_tag="IXT22_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4862748.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1677..2117)
                     /locus_tag="IXT22_001373"
     CDS             complement(1677..2117)
                     /locus_tag="IXT22_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4862749.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(2174..2584)
                     /locus_tag="IXT22_001374"
     CDS             complement(2174..2584)
                     /locus_tag="IXT22_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4862750.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(2764..3198)
                     /locus_tag="IXT22_001375"
     CDS             complement(2764..3198)
                     /locus_tag="IXT22_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4862751.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(3298..4146)
                     /locus_tag="IXT22_001376"
     CDS             complement(3298..4146)
                     /locus_tag="IXT22_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4862752.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            4535..6301
                     /locus_tag="IXT22_001377"
     CDS             4535..6301
                     /locus_tag="IXT22_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAQ4862753.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            6403..7662
                     /locus_tag="IXT22_001378"
     CDS             6403..7662
                     /locus_tag="IXT22_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4862754.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            7809..9110
                     /locus_tag="IXT22_001379"
     CDS             7809..9110
                     /locus_tag="IXT22_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862755.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9113..9964
                     /locus_tag="IXT22_001380"
     CDS             9113..9964
                     /locus_tag="IXT22_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4862756.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            9977..10792
                     /locus_tag="IXT22_001381"
     CDS             9977..10792
                     /locus_tag="IXT22_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAQ4862757.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            10943..12109
                     /locus_tag="IXT22_001382"
     CDS             10943..12109
                     /locus_tag="IXT22_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4862758.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            12339..12986
                     /locus_tag="IXT22_001383"
     CDS             12339..12986
                     /locus_tag="IXT22_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAQ4862759.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13070..14014
                     /locus_tag="IXT22_001384"
     CDS             13070..14014
                     /locus_tag="IXT22_001384"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAQ4862760.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            14149..15600
                     /locus_tag="IXT22_001385"
     CDS             14149..15600
                     /locus_tag="IXT22_001385"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAQ4862761.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            15621..16457
                     /locus_tag="IXT22_001386"
     CDS             15621..16457
                     /locus_tag="IXT22_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4862762.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            16457..17116
                     /locus_tag="IXT22_001387"
     CDS             16457..17116
                     /locus_tag="IXT22_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4862763.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            17242..17931
                     /locus_tag="IXT22_001388"
     CDS             17242..17931
                     /locus_tag="IXT22_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862764.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            17937..18893
                     /locus_tag="IXT22_001389"
     CDS             17937..18893
                     /locus_tag="IXT22_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAQ4862765.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            18937..19449
                     /locus_tag="IXT22_001390"
     CDS             18937..19449
                     /locus_tag="IXT22_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862766.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(19705..20253)
                     /locus_tag="IXT22_001391"
     CDS             complement(19705..20253)
                     /locus_tag="IXT22_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4862767.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(20342..21523)
                     /locus_tag="IXT22_001392"
     CDS             complement(20342..21523)
                     /locus_tag="IXT22_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAQ4862768.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(21759..23267)
                     /locus_tag="IXT22_001393"
     CDS             complement(21759..23267)
                     /locus_tag="IXT22_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAQ4862769.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            23426..23617
                     /locus_tag="IXT22_001394"
     CDS             23426..23617
                     /locus_tag="IXT22_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862770.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            23820..24737
                     /locus_tag="IXT22_001395"
     CDS             23820..24737
                     /locus_tag="IXT22_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAQ4862771.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            24730..25803
                     /locus_tag="IXT22_001396"
     CDS             24730..25803
                     /locus_tag="IXT22_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862772.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            25951..26469
                     /locus_tag="IXT22_001397"
     CDS             25951..26469
                     /locus_tag="IXT22_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862773.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            26450..26842
                     /locus_tag="IXT22_001398"
     CDS             26450..26842
                     /locus_tag="IXT22_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAQ4862774.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            26918..27853
                     /locus_tag="IXT22_001399"
     CDS             26918..27853
                     /locus_tag="IXT22_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAQ4862775.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            27986..28765
                     /locus_tag="IXT22_001400"
     CDS             27986..28765
                     /locus_tag="IXT22_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAQ4862776.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            28758..29075
                     /locus_tag="IXT22_001401"
     CDS             28758..29075
                     /locus_tag="IXT22_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4862777.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            29319..30929
                     /locus_tag="IXT22_001402"
     CDS             29319..30929
                     /locus_tag="IXT22_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4862778.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            31086..31934
                     /locus_tag="IXT22_001403"
     CDS             31086..31934
                     /locus_tag="IXT22_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4862779.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            32165..32644
                     /locus_tag="IXT22_001404"
     CDS             32165..32644
                     /locus_tag="IXT22_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862780.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            32677..34905
                     /locus_tag="IXT22_001405"
     CDS             32677..34905
                     /locus_tag="IXT22_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4862781.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            35034..36677
                     /locus_tag="IXT22_001406"
     CDS             35034..36677
                     /locus_tag="IXT22_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4862782.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(36750..37295)
                     /locus_tag="IXT22_001407"
     CDS             complement(36750..37295)
                     /locus_tag="IXT22_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAQ4862783.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(37318..37803)
                     /locus_tag="IXT22_001408"
     CDS             complement(37318..37803)
                     /locus_tag="IXT22_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4862784.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(37793..38605)
                     /locus_tag="IXT22_001409"
     CDS             complement(37793..38605)
                     /locus_tag="IXT22_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAQ4862785.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(38744..>39854)
                     /locus_tag="IXT22_001410"
     CDS             complement(38744..>39854)
                     /locus_tag="IXT22_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4862786.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        13175 a         7201 c         7809 g        11669 t
ORIGIN      
        1 tccagaagaa aaaccagatg tgactccaga accagatacg gacgcaagag accaaggaat
       61 accagaaaaa ataaacaaaa aaacaattca agaggatgga aaaaaagaga gtaaaaaatc
      121 aaatctagca attctaaaaa taaatgaaga gcagctgaat aaaaaatcac gaatatttga
      181 tagcgcccaa tcagctgaaa ccttaaaaag tagcaaggat acaacctttg ctgtcctgaa
      241 acgaaaaata aacagctacc aaaatccgga gagtcacaaa acaaagttat actgtggagc
      301 ggaatcattc tattaagtat agcaacaatg ctttctgcaa aaagatttaa acaaaacaga
      361 tctctctaac atttgaataa tgtctgtgaa cgcatttttc aaataaaaag aaatatccag
      421 aaaatgaccc caaaatacca gattgaaatc tgatatttgg ggtcgttcat actttatctt
      481 tcttcatatt tattttaagg gatatctgtt tcttttggaa gatggttcgg gatctttttc
      541 actttcaata catctaaaaa gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg
      601 ccaaagaacc gttcgctaac aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt
      661 ttgctggaca tcaacttcgg attcagcaca taagactcaa ttagatggac aatcaaaatc
      721 gtaatcagga tataaacaac atctcggatg cctccttggg aataagctat gaaagataga
      781 ggaatacaag aaatgataac acctgctact gggatcagac ttaaaatgaa aatcatgatc
      841 gctaaactca gcagctgatg aaagccaaat acagccaagg cgattgtagt gagcaacgta
      901 tttaaaagag cgacaacaaa ttgagcttct aataccaaac caaatgtatt gacaaactta
      961 tcggcaaaat agtaaatatc ttgaaagaac caagaaaatt cactttttaa aaacaatctt
     1021 gagaatacaa ttgttttttt cttttcaatc ataaaaaaga aacttaagat gaatgacata
     1081 gcaaacgcca ctgccatttt tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca
     1141 ttttgaagct gttcaaaaaa atcgtttcgc tcaatataag tatggatata ttgtaaaaca
     1201 ggatctgcat cttttggctg atgctcgtaa aaattaataa cggactggat catgtcaaat
     1261 gtttgatgaa taagcatcgg gatatacttt gtgaatgcca gatagataag gtaaacgatc
     1321 agtgtataaa tcatgatagc taaaacacct gtagggattc ggacaaatcg ctgaatgatt
     1381 tgaacaagat gaatcatcaa ataagtaaag ataaatgtga gcaaaatggt tgtaatcata
     1441 cttctaacta agaaaagaac aaaaacgaca aataataaaa cagtgagacg gcgtattttt
     1501 tcattcgcca aaaaacgctg ataaacggtc aaatcgacaa cctccaaata acaaaaaata
     1561 aacacgttat tcattatatg atggaatatg aaaataagaa agagcaaaaa gaaaaaccgc
     1621 taaatgacgt tatcttatga gttggttttc ctcataaaat cgttcatcta gcagtttcag
     1681 ccctttttct ggtcttgatg aaaattatct agcatttttc gggtcagatg ttgcagtgta
     1741 tccaattctt cctgttcaag tggaagataa gacttgatct tttgtggaat accttctgct
     1801 tgtttttgca acgcagcacc ttgagcagtc agcgtaacat ttacgattct ttcatcaccc
     1861 gtttcacgct gacgattaat ataatttttt tctgctaact tttttagtaa gggagtcagc
     1921 gtaccagaat ccagacacaa atcatttcct agctctttca ctgaagtctt tttcttttcc
     1981 cataaaacta acatcacaag atactgggta taggtaagat tcagcggctt gaggagggga
     2041 gtgtagtgtc taatgatttc tttagaggcg gcatataaag gaaaacatac ttgattaact
     2101 aaatatagat cttccatttt tccacctccg ctgttttact atagtgtatc atagcggatt
     2161 tacacaaaaa agtctattca ctaactgctt tcagagtaac ttctatattt ccagctgtag
     2221 cttttgaata cggacacact ttatgcgctg cctctaataa ttcttgcgtt tcttccagag
     2281 aaagaccttc gatagatcct tcaatctcta cacctaagac aaagctcgtt tcactttctg
     2341 aataaaggga aacttgtgca ctgacagtag aagccccaga gatatttttt tgctgtttga
     2401 tcaattctaa tgcactgtta aaacatgcac tgaaaccagc tgcaaacaat tgttcagggt
     2461 tggttgcatt ttcgacgcgt ttaccaggag ctgcaatatt caattcgaat gtacgatcgg
     2521 gattatgcac ttctccagag cgtccgcctg tgttgatcat tttcgtagaa tacatttttt
     2581 tcataaaatt accaccttta attatatttt atacaattga attttacaca atataattgt
     2641 ggaaagcaaa gaaatggatt ggcataagat aaataagaga aagcacatga aacagacgcg
     2701 ctttctcgaa tagcaaacat atacaaaaaa tatcagagac aaaaaataat ctcatcataa
     2761 acattacata tatttctcaa aaagttgttt tctttcttca aaaattactt cacgatggac
     2821 ctgatgaagc atccataaat aaccaaaagg atctctgaac attgagttag tcacaccaaa
     2881 gtccatcatt tctgtcattt cttgaatctc tacacagcca tttcgtaatg ctttattatg
     2941 tgtgtcctcg atatcagaga cgatgatatt gaaccagatc gtatttggat gttcagcagt
     3001 aggagcagtc aaaccaagag acgtgttttc atccagcata tggaatctcg taccatacaa
     3061 ggtaaaaatg acttcattat tgcctctagg gtaatctgtt gcctcaatca gttgtatttc
     3121 atcaaagatt gtttgataca gttctagtgc tttcaaacta tcatttaata caaaatcgat
     3181 ttccgttcct ttatgcataa agatctcctc tccttttcag tcgaacagtt actagattct
     3241 tttattatac cagctaaaga aaacgcattc aaaaaaatag cggatttact taccaactca
     3301 ttcgattgga tgataagtaa atccgcgtcc cattacttct gctacgctgc tgacaatgac
     3361 aaaggcactt ggatcgattt cttctatcaa tggtttcatt cgggaaaatt catgatcagt
     3421 cacaacgatc aataaaacct cttttgactt tcgattatac ccgccttttg cctctagcag
     3481 ggtaaggcca cgtccaatct cagcacttaa gcgaaggcgg atgtcttcca aataatgttc
     3541 actcatgacc ataacagatt tctttcgatt gatacctgtt tcgatataag tcatgacaat
     3601 tgaagtgatt gcaatagata aaatagcata aagaaactct tctattccaa aaataaacag
     3661 attaagagaa acaacgaatg cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa
     3721 atatttttta aaaatgaggg gagggatcgt cgtaccgccg ctagaagagt tgtttttata
     3781 taaaatcgca actcctaaag caaaaatcgc acttccaaaa atgacagaca acaaccgatc
     3841 tgaagtaatc attgtttctg gaactattgc aatgattaaa ggaaaaacca agcttccgaa
     3901 aagtacttta aaaaagggtt ttttacctaa aaatagaaga gctagtacca acataacgat
     3961 attcaacact aaaataacta tagctcggtc aaagcctaaa gcagcttcca gtaatattcc
     4021 tagaccgctg acacctccag cagcaatatg atgaggccct aaaaacatat tgatagcgac
     4081 tcctaatatg aagagggcaa aaataatctt aatgtatgtc catataaatt gtctcgtttc
     4141 tttcatttat tcacttcctt aattcattaa taatactctt atcttattat aacttacttt
     4201 tcaccttaag ttaactttaa ttaataaaaa aattaggcta gtctaaatta ttatgtttca
     4261 ttcttctaga atatacttct acgccaaaaa ctgttaaaaa acttttactt tagaaaattg
     4321 gagaaattga tcgcttaaga taaattcagg acactaaata gtacaggaag tagactaaaa
     4381 cttttaaaag ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa
     4441 aaaactgtta ccgataacat ttttgaaagc gttgtctttt gcttctctat cacttatagt
     4501 gatgacgtca tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg
     4561 accggaaagt gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac
     4621 taggaaaaat gatatcaaaa aagtatatgt gctatgtgga gatccatata ccataacaac
     4681 tgaaaaatgg tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga
     4741 ttattgggaa attgaagtga cgagcgaaac aagtcgctta cagtatgcgt tccatgttgt
     4801 tggggaagat aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa
     4861 tgtgattact gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt
     4921 cactattcca gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc
     4981 aaacggggac aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga
     5041 ccgagaagac tttttcgggg gagatttgca aggtgtgatg gatcatttgg attacttgac
     5101 ggaccttggc atcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa
     5161 atacgatacg attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa
     5221 aaacttgatt gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa
     5281 tcatatgggt gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat
     5341 ctataaagac tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt
     5401 accagaaact gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa
     5461 actaaataca gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat
     5521 aaaagaattc gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt
     5581 ttggaaaaaa ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga
     5641 gatttggcat tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta
     5701 tgcatttaca gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat
     5761 ggtcagtgga atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt
     5821 caacttatta gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga
     5881 attgatgaag tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta
     5941 cgggacagaa atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg
     6001 ggagaaggag gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag
     6061 gaaacagttg tctaagatta tttctgaagg ttctactcag tggctaatag taaatgatcg
     6121 tgaagataag ctctatttca cacggaaact agagggacag atcatctatg tttactttaa
     6181 tcagtcaaaa gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg
     6241 tcagttgtta gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg
     6301 aaaactgtta ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa
     6361 taagggtgta acagcacgtt gaatacaaag gaggaaatga agatgaaaaa aagaagtgtg
     6421 aaacagttgg gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc
     6481 aatggtaact cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt
     6541 gattctggat ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat
     6601 gtgaaaatca agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat
     6661 gggcctgctg gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta
     6721 ggacagcaag gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca
     6781 gacaaagccc aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc
     6841 cttgttttgt actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg
     6901 gagaatctat ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga
     6961 tttttagcta aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc
     7021 tatgtatttg gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct
     7081 gtagaaggaa tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa
     7141 gacataaaaa gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca
     7201 atcattgacg gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta
     7261 gccaaaattc ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga
     7321 tgggtagtca gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta
     7381 acgaatcagg aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa
     7441 caagctaggg aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa
     7501 tatgaaacag ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca
     7561 gaaaacttga tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa
     7621 gcagtaaaaa caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc
     7681 atttttataa aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat
     7741 tatcttgctc ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg
     7801 gcattcagat gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt
     7861 cacttattcc agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt
     7921 tcgccatatt cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag
     7981 gattggttac tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag
     8041 gcactttgca attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag
     8101 acgcttatcg agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg
     8161 aagtcataca taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc
     8221 ttctcatgat ttttacgatc attttcccag tcctagttac attgttcact gcatttacta
     8281 attatgactt caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact
     8341 tttttagtat cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga
     8401 ccgtgatttg gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg
     8461 ttgttgctca ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac
     8521 catgggcggt cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg
     8581 taggtgccat caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca
     8641 gtgcaatctc ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg
     8701 gctggttagg atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag
     8761 aagacttata tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca
     8821 tcacgcttcc tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga
     8881 atttcaataa tttctccatg atctatctgt ttaacaatgg cggtcccgga agcgtaggcg
     8941 gaggagctgg ttctactgat attcttattt cctggatcta taaacttacg actggaactt
     9001 ctccgcagta ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg
     9061 tgtcattgct ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa
     9121 atttcattcg agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct
     9181 tttaatactg tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa
     9241 gtcaggaaat attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt
     9301 tactcggcta ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc
     9361 tgtcctaaca atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg
     9421 ctatcgtttt atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc
     9481 gactatggca gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa
     9541 gtactggttc ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat
     9601 gaaaggatac tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc
     9661 agggcatttc aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt
     9721 tcaagcatta tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct
     9781 tcgaacacct gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac
     9841 aaaccaaaga gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct
     9901 attattcttc tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg
     9961 ataggagcag agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc
    10021 aactcaagtg tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt
    10081 atttttagtt tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc
    10141 gattccatta gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa
    10201 attttctgaa cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt
    10261 gacccctgaa attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac
    10321 ttttattgat tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg
    10381 ccgctatacg atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga
    10441 tttccaacga tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc
    10501 ttatagttta agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc
    10561 ttcctttttc ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga
    10621 gagtgcaaat ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg
    10681 gtttatccac tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct
    10741 gcttttatgg gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta
    10801 agcgatttat gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt
    10861 tctgaaaaaa ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt
    10921 agttttttta aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg
    10981 ttctttctcg ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga
    11041 tacggacact cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat
    11101 tacaagtaac gcttctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga
    11161 gggaagtatc caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg
    11221 aaaagattat ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga
    11281 agatatccat gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac
    11341 tttgacttat tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat
    11401 caataaagtc catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga
    11461 tatcggttgt ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc
    11521 aactgggatc acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga
    11581 acatttagaa gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac
    11641 gtttgatcat atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg
    11701 ttatttcaaa gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat
    11761 cagccgacaa caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg
    11821 ttatgtccct ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat
    11881 tgatttggaa agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt
    11941 tcatcaagtc caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga
    12001 tctatattta caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata
    12061 tttgcttgtt caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa
    12121 gtactgttta aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt
    12181 ttttgtctaa cttctaggat tgtctctaaa gcttagtttc tttttcttta tattttcata
    12241 ataaaagttt ggttctttaa tttttaaaca tgacagaaaa ttttttcttc gttatacttg
    12301 taatagaata ctattttata acaaagggga tcgaatcaat gaaaaaaact gttatttata
    12361 ctagtttatt tgcagctttg tttttagctg cttgtcaatc aaataccaat caaggcacat
    12421 ctgggaatac gtcttccagt agcgaacagc gctcttcaca ggtatcggac tcctcaacaa
    12481 aagcaagcac atcttcgtct agccagacaa aaagttctag tgaagcaagt actcagtcag
    12541 atatcaaagt gtctgcagct cgtgcgatcg aattgttcca agataaatac ccagatactg
    12601 caattactag tttggaatta gatagtgatt ggggatctta cttctacaag atagaaggtg
    12661 tcgatgatca aaaagaatac gaagcaagaa ttgatgctca aaatgaaaaa atggagacag
    12721 agaatccaga aactctagat cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc
    12781 tggatgttga taaattgatc acgattgagg aagcagcaaa aatcgccgtc gacaaagtag
    12841 gaagcggtac ggcaacagat tgggatttgg ataaagattt aggtactact tattgggaag
    12901 tcaaagtaaa agacggcaat caaagtacat cagtcaagat caatagccaa acaggcgaag
    12961 tactgtcaac tgaacaagat gattaagaat ttcttcggaa aacaagagtt gatttttctt
    13021 ttagtcatga tacactagac aaaataactt gtttgaagga gcgatttact tgagtttaga
    13081 aacgaccttt gccaatcata tctttgccaa tcctttgatg aatgcatctg gtgtccactg
    13141 catgactacc caggaattag atgaactggc tcattcagaa gcaggagcat ttatcactaa
    13201 gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca cgctattttg atgttccttt
    13261 agggagtatc aattctatgg gacttccaaa cttaggtttt tcttattatc tagagtatgc
    13321 tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg ttattttttt ccattgccgg
    13381 gatgagtgtc caggaaaact tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg
    13441 gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga aaaccacaac tagcttacga
    13501 ttttgaggcc acttatgaaa cactgaaaga agtattcagc atcttttcta agccgctagg
    13561 aatcaaattg cctccttatt ttgattttgc tcattttgat cagatggctg atatcttgaa
    13621 tcagtttcca ttgacctatg tcaatgctat caacagtgtg ggcaatggtt tgtatatcga
    13681 tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga
    13741 gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga
    13801 aatccaaatc attggtacag gtgggattcg gacaggacaa gatgcatttg aacatctgct
    13861 atgtggcgca agcatgttac agattggtac cgagcttcat aaagaagggc cggaaatttt
    13921 ttctagaatc ataaaagaat taacgcagat tatgtcagaa aaaggatata cgtcaattga
    13981 cgaatttaaa ggcaaattac gcaccatttc atagcaaaga gacgaaggtc atgattgatc
    14041 ttcgtctttt tttataaaaa acactcgtct gttcattcct gtgcaagcgt actcattgta
    14101 tgttagacga acttgtggga aaataacaga ggcaaaaagg aggataatat gaatgatgca
    14161 acagaattag caaaagagct taaagaaaaa gaatttagtt ttcaagaact agttacggat
    14221 atacagaaaa aaataaagaa gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca
    14281 ttcgagagta attcccacga gctattgatt ccccagtcag aaaaagggcc attggctggt
    14341 atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg gatggctagc tacttcagga
    14401 tctcgtttat ttgaaacaca ccgagcttct catacatcta attatgtgcg gcaagcagaa
    14461 gcgataggtc tagttccttt tggacaaacc aatgcgccag agtttggttt caaaaatatt
    14521 acagacccag tcatctatgg cccagcaaga aacccttgga accttgaatg tacaccgggc
    14581 ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa tcgttccttt agctggtgct
    14641 agtgatggcg gtggttctat tagaataccc gcttcgtttt gcggattgat tgggctgaaa
    14701 ccttcgcgag ggacgatgcc agttggtcca tatgcttgga gaggatggca aggagctgct
    14761 attgatttcg gcttgacagt ttctatgaga gacacggagg ctttatttta tgggatgaga
    14821 agtatccatt ccggtgcgcc atatcaagta tcgccagttg agtggcaaac acatccaaga
    14881 aaaaaacggt tgaagatagc tttttgtgtt gattcaccga tccactcaca gattagtgaa
    14941 gaggcagtac ttgctgtaaa aaaagctgta gatttccttg gaaaagaagg gcatgatttg
    15001 acagagattc cttacccact agatggtcgt aaactgatca cgtcttatta tcagatgaat
    15061 ggcgcagaaa cagcagcaat gatccgctcg attgaaacag gcatccagcg agctgtcaga
    15121 aaagaagaac ttgaacccat ttcttggact ttgttccaat atggtcagaa gctctctgcc
    15181 gctacttaca tcgattctct gcatgtatgg gatgaagcag caattgtcat ggaaaaccta
    15241 catcaagaat acgatctatt cctttcacca acgactgcat ttaccgcccc taaaatcagc
    15301 gaagatttgc aaagtgatgc gataagagca cagatggaac acatcagtga ttgttctgaa
    15361 gtagaaggtt tagacgttgt ttcttccatg tttgaggaga gcttgaagat cacaccttat
    15421 acacagttgg ctaatctgac tggacaacca gcaatcagct tgcctactca tttgacaaaa
    15481 gaaaacatgc ctctaggaat ccaatttatg gctgccagag gaagagaaga tttgctattt
    15541 caaatcggct atctatttga agcaaatcat cagttccatt taccaaatcc atggaaatag
    15601 cagaaacaag gagaagaaga atgaagaaaa aaagattgtt tgctctaata actagtgcct
    15661 tttttatttt aagcgcttgc ggtacagctg ccgctaatca ggaagataac agctggagta
    15721 atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg cacactgttt cccgcatctt
    15781 attataatga tcaaaatgaa ttagttggtt atgatgtaga tttggcaaaa gaggtggcta
    15841 aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt ggatggacaa atcacttctg
    15901 tttcaaaaag agaatcagat tttgctgcga acgattttgg tatcacaaaa gaaagagaaa
    15961 aaaaattctc cctttcagag actttcaaat attcatttga cagtatgatc gtacgaaaaa
    16021 aagatgattc aggaatccac tcacttgaag atcttaaagg gaaaaaagca gctggcgaac
    16081 ccaatactag ctatatgcgt ttagcggaaa aacacggagc taaattagtc acatatgaca
    16141 atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg tcgaacagat gttattctaa
    16201 atgattatta tctgcagaaa atggccgtat ctgctttacc agatatccct gtaaaaatac
    16261 tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg
    16321 ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa agaagatggg acgacaaaga
    16381 aaatatctga aaaatatttt caaactgatg tttcagtcaa accgaaagaa acgatggctg
    16441 agtcggtgag tgagtgatgt actttcctct aattgatttt tccctcatgt ggacttcact
    16501 tcctttcgta ctgcaaggct tggtatacac attagggatt ggcttcgtgt cgtttctttt
    16561 aggaaatctg gtagggttgc ttttgacagt tttaggtctt ttggattggc tgcctctgaa
    16621 tgtatttatt cgtttttatt tatcgttctt tagaggcatt cccgcactag tcctgctgtt
    16681 tctgttatat tttgggttac cttatcaatt aagtgcctta acggcttcag tcatctgctt
    16741 tacgattacc agcagtgcat ttattggtga aatctatcga ggatcactag caggcgtttc
    16801 ttcaggtcag tgggacgctg gtttagcttc tggtttttct ttctttgggg tattgaaata
    16861 tatcgttttg ccgcaagctt ttcgaatctc agtaccggca ctcagtaacg tagctatgga
    16921 tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc
    16981 aaagatcata ggcggtcgga cattcgatta tttttctctc tatattttag ttgcactgat
    17041 ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag tatttagaaa aacgttctat
    17101 gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg ctggcaccat ttctattttt
    17161 tgtttcttgt atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa
    17221 atatgttcgg aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta
    17281 taccaatatt gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac
    17341 caaggaattg tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga
    17401 tgctatgagc tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt
    17461 ggacattata attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc
    17521 cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc
    17581 tctggtacat ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa
    17641 gctttgacaa accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg
    17701 gagcgaggcg taaaatattt tccaacagat caattgtaca aagaattgaa aagacgttca
    17761 gaaaatcaag atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct
    17821 agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat
    17881 ttgaggcaac aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt
    17941 actatcctta tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc
    18001 gaggattgct ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc
    18061 ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc
    18121 cccaagtagg acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa
    18181 atagctctgt cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt
    18241 cacctccagc gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga
    18301 aacagttggc aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct
    18361 ggctgcccga aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa
    18421 gttatgcaga taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg
    18481 gatatattgg attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc
    18541 ctagccgagc gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga
    18601 aacattttgt ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag
    18661 caggagataa aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag
    18721 gaatgattga attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga
    18781 aaaagtggtc acttatgcat catttggaac ttattagtca cctgctagat catccaaaag
    18841 attggcttaa atattattca aaagttcagg aactatatga agtgatccaa tgattagata
    18901 atgtaaatga aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa
    18961 gaagaagtag aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa
    19021 ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt
    19081 gaaagaaaag aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta
    19141 gtctcaagcg tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt
    19201 ccttatttat cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca
    19261 aaaccgttct tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt
    19321 atcgatactt atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact
    19381 tatcaaggga tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc
    19441 atcaattgac tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac
    19501 aatcatatga tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa
    19561 tttccgaaaa tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct
    19621 ttctgaaact cccttcatcg agaggtcgtg acatagcttt tgtcacgacc tctcggctta
    19681 tcctacgagt attattcgat acatttatat caataatcct ttttttattt tatctgcagc
    19741 ttcttggaac gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt
    19801 caactgtgct aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc
    19861 tccacgtttt ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg
    19921 gactaccgtc ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta
    19981 acaatttcct actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg
    20041 agcatattgg tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc
    20101 agaaacaaaa taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta
    20161 agtaatgatc ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc
    20221 agaaggaccg ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca
    20281 agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat
    20341 attataccag caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca
    20401 aaattttcaa tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg
    20461 caccagaaat gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa
    20521 ttgctgttgt acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa
    20581 attcatttgt aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg
    20641 ggattccgct gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga
    20701 tgccgaatat cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa
    20761 gcatagcagc aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt
    20821 ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata
    20881 catagggatt tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag
    20941 tgatcacata tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg
    21001 tagacatagc cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct
    21061 tttttatgga aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag
    21121 attccaattt gcccatcccg ttgattttac ttaatcctag accaacagct ttcataaata
    21181 atggaagaat cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca
    21241 tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt
    21301 caacaccttg cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa
    21361 ccgctgtacc aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca
    21421 tcacaattag tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc
    21481 ctaatgtgac aaataaacca ataataccta ataaataact caaataatca ctcctattcc
    21541 aaattccgtt ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca
    21601 ttactttttt agagtgaaac gcattcattt tccattagaa aataaagcga acaaaataaa
    21661 aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa aacgaaacta tcgattaagc
    21721 taatagtttc gttttcaaca tttataagta aactttttct attggtaata tagattttcg
    21781 gaagggtaga caggtgcgca ggtaatatcg attcctagtt ttttcaatgt ttgttcatca
    21841 tttttattga ccatcacagt agagtgggct tgtgctccct caagttcagc tagtttatca
    21901 taagcaactt gagcgattgg attcgttact gcactgattg ataaagcgat caagacttca
    21961 ttgatgctta gtgcatccaa agaggaatga agtgtctttg atttcaatcc ttgtattgtt
    22021 tcaagaacta atggtgacaa taaaggaatg tcatctgcga tatgggctaa atgttttact
    22081 gcatttaaga taactgccgc tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg
    22141 acttcatctg gtaattcgat tgcaatcaca gcagaaggat cttttgtagg actttgcgct
    22201 tgaatcttat ctgcatagtc atgggcaggg actaccacgt ttcggtcttc aggacgtaaa
    22261 ccgacttctt ccataatcag tttgattcga ttaactgctt cttcgtcgat caatcctttt
    22321 ttgaagtcgc attctgtttg gaaataacga cggatgattt cttgtttaga ggcttcttgg
    22381 acaacggtat catccacgat cccaaatcct acacgattca cacccatgtc agtaggagat
    22441 tgataaacag attctttacc agtaattttt tcaataatac gtttgattac aggaaatgtc
    22501 tcaacatccc gattatagtt cacagctact ttattgtagg catcaaagtg gaaggaatcg
    22561 atcatattga catcttttag atcgactgtg gctgcttcat aagcaatgtt cagcggatgt
    22621 ttcaacggaa cattccatac tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct
    22681 ttttggcttt catgatacag ttggttcaag gaagtagcga gctttccact tcctgggcca
    22741 ggagctgtca ctacaacgat tggtttagtt gtttcaatat actcattttt tccaaaacca
    22801 tcttctgaga cgattttttc tacgttgact ggatagtctt cgatttctga gtgtttatag
    22861 accttgatgt ttcgtctttc tagtttattg ataaagactt tcgtggcagg ctgtccacta
    22921 tagcgagtga taacgacact gttgattaat aagccataac cacgtaattc atcgattaac
    22981 cgcaagatat ccatatcata agtaatccca taatcaccac ggatcttatt acgttcaata
    23041 tctccagcat agacgcaaat cagtatttca gcttgatctt tcaatttttg cagcaatttg
    23101 attttcgcat cttcttcaaa tcctggaagt acacgtttcg catgcttgtc gtcaactagc
    23161 ttcccaccaa attctaaata taatttgtca tagtggttca ctcgttccaa aatatacgct
    23221 gactgctctt caatatattt ttctgaatca aaaccaattt ttttcactag gttccctcct
    23281 taagtactaa agcatttttt catttttttg aggattcgtc aactggaaga gcgaaattcc
    23341 tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag atagttattc attggtatga
    23401 tagtttttga taaggaaggt gctacatgaa aaaaagacag aaaaagaaaa acgcatataa
    23461 acactatatc cgttcgattt ttaccggtta tgaaagaatg cttgaagatc ccgaattgga
    23521 acaattgacg tttacttatc taaacgaaga aacgcagcta actcgtgatg agcatcagcg
    23581 cattcatttc acaacaagag atctgcctag taaataaaaa ataagataaa ggtcatcgga
    23641 ttcgattctg tcctatcaga tggaaagact agttgatcga aaaaaaggct gtaccaaatt
    23701 ttggtgcagc ctgttttatg gagcattgcc cgctcttttt tataacaatt ttttacagaa
    23761 aatggtacta ttgaagtatt aataagtgaa aaacagatga gtaagaggag gcaagtagta
    23821 tgaaagagcc agatacaaat gcaaattatg agccagacga actagaggag acgaatgcgg
    23881 atcaggatac aggacaagaa tcgtcttctt tttacgatat caaagaaaaa gcaagcatga
    23941 atctttccca attattagaa gacttacagg cttttgaaaa agctgtccgc gaagaagata
    24001 tccctgagat ctaccgttta tacaatggcc gattgaatga agaattaaaa agaagctcaa
    24061 atgaaaatca cgagatcgat caattgctga tgcgtaagat ccatgatcgt tttttacagg
    24121 aatttccttt tatggaacaa gtagaaaaca tctcgccaac gatgagctat tacaaaatcg
    24181 gcacttatta ccatgatcgg cccacggtcg gtattgatgc aagtctgcca gaaatttttg
    24241 ttttgcctaa gatcgatgaa gagtgggaga aatattccca accggagtca acggactatg
    24301 acaaaaaaat caatgagcta gacgcaaagg tgatcactgc tcagacagaa attgaacgtt
    24361 tagatgaaca aataaaagaa atcaatcgac aaatgactga tttgaacgac aataaaggat
    24421 tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt agagaagaag aagcaagtac
    24481 tatctaatga aaaattaggc tggcttcctt atattgagac gcctgaaaca atccagcagc
    24541 aaaaagaagc attgaagcaa gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa
    24601 aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga gggattcggt caagcaatcc
    24661 atgaattctt gatgaattat cttggcaatg agaatcctaa taatcaatct aatgaaggag
    24721 gttccgagta tgaatgaaca cgatgaagca gaatggacaa aaaatgaaga acaaacagaa
    24781 gatcatgaag aaacgaacac ttcattggaa gaacaaacaa gtaatcctct ggatgacaca
    24841 gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa aagaaaaagt aactccgacg
    24901 aatacgaata ctgcagaaaa cacccatgct tacgaaataa ctgaaaatcc cgggtattta
    24961 gaaggaaaag agcaagatca tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa
    25021 ttagcggatt tacgtatgag aaaagatttg atcgaatcag attttccaca attattagaa
    25081 tcatatgatc gttttatatt gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg
    25141 atcgaatact tcacgtatga attactgaaa ccgttgaatg atattggtct ggaacggtca
    25201 aattcagctt atgacacatg gaaaacaaga catttttcga tcaattatac gttgaatgga
    25261 caaaacgaat tagtcttttc ctttgtatta ccgaccatcg atcaacgata ccaagtggaa
    25321 tcgatgagtc tcctaaacgt atcaccagag acaatggaaa tcaatgtcca agatgaccgg
    25381 gtgctttctt tgatccgaca ctggtcagtg gatcgagtat tctctgcagg gcagatcacg
    25441 atattcaatc acaaattgaa tcaattatta gcccatgcaa gaacacttgg ttttaccgtt
    25501 aatcagacat tactagacaa tacgaagcca cttcgtttga atcttcagag cgaatttgaa
    25561 ttgacgaatg aagtattgga tgatattttt atcgtggcaa tgaaaaatcc atcctacgat
    25621 atggaaaaga tcaacgaaac tacttatcaa gtacgattag ataaaggaca gtctttaacg
    25681 ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct catctggaga ctacccacga
    25741 tctgtcattg atttctttat caattacgaa ttcttggtcc cattaatggt gagaaagtcc
    25801 tgattggata agttggatta ccagatgtca ttcagataat tctgttccaa aggacttgcg
    25861 gcagttatcc agaataattg tcacaagtct tttctgtatg tactaaatgg acgtgaataa
    25921 cttgctgatg aaggagggat ttcattagga atgtccacaa ataaaatagc acagcttagc
    25981 ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc aatttattcc gaatttccag
    26041 ccaatgactg ctattttttt atttatagta ctttacttaa gcttaaaaga tgcgttaatt
    26101 gtcatgagtc tttctattgc gatcagcagt ttttattttg gtgttggacc atgggtcatc
    26161 ggccaatgga tcagctatac tgttgttctg agtttgtttt caatcgtctg cttgagaaaa
    26221 acagtgcaaa ggaatctatg gttaaaggga gtctgttttt ttctggcggg catggtttac
    26281 ggaataggta tgaccgtttt tgatacgctg ttatatcgtt tgcctcaacc ttggatctat
    26341 taccttcaag gggtgtcgtt tgatttgatg cacagtatag gcaatgttgt gttctttctt
    26401 gtttttctgc cagtcgtcaa acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat
    26461 aatttatagt ttgcttgcaa tgagtgtcag tatactcatt ttgacaagtt gcagtacaac
    26521 ctatacacaa tcggcttcca accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat
    26581 cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa gtgttcttca aaaaaggcga
    26641 tgatttactg agtattttga aacgaaattt tgaagtcaaa gaagataacg gcttcatcac
    26701 ttcgcttgaa gggcactcac aggatgagaa aaatcaactc tattggatgt ttactgtgga
    26761 cgggaaaagt gctactactg gtgccaaaga gatcaaattg aatgatggac aatcggtcat
    26821 tttcaatttg tctaaactat aagtttcata aaaaactgtt aaagggcgaa tattgccata
    26881 attcagtgag ttcagttgat gaaagaagga aaataacatg gaaaatttta aaaaaagcgg
    26941 aatgttttcc gtaattgctg ctctaggggc taatattcta gttgctatca gcaaatttgt
    27001 cggctatgca atcagtggca gtgccgccat gctaaacgaa agcatccaca gtatcgttga
    27061 ttgcagcaat cagattttgc tgttattcgg tgataaacaa gccaataaag gacagagcga
    27121 gttgcatcaa tttggtgaag gacgagcaaa atactttttc agtacaatcg tcgcaatgat
    27181 gcttttcttc ggcggtgggg cacttggggt gatggaagct tttgaaaagt tgacgcatcc
    27241 atcccatgaa gtgggtaatc cgatcattgt tatagcaata ctgttatttg gtttggtaat
    27301 cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact
    27361 ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa atactgatta tttttacgga
    27421 agacttgtgt gctgtaatcg gtttggtctt ggctttagca ggaacaatat tgacttatgc
    27481 aaccgggatt gctgcatttg atgcgatcag cggattgctg atcggtttct tgctgatggg
    27541 agccgccatt ttcctagcaa aagaatttta tagtctgatc atcggtgaaa gcgtgacagc
    27601 aagcgattta tcaaaaatca agttagcttt tgaacgtcct gagatcagtc ggctgatcga
    27661 tataaaaaca gttcatttaa gtccaacgga gattttagtt gcagcaaaag cagatatcgt
    27721 tggtaacaaa gagaatgaag cttactcggt catcaatgat attgaaaaaa atatgcgtca
    27781 gtctcttcct gacaagaaga tgtatatata cattgaaaca gataaatatg acccaaatta
    27841 ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa atgagaaaaa tataatcttg
    27901 tttttaaata aaacggctac aatttagcga atttatgtta caatgagtcc gctgtttatt
    27961 tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc
    28021 tttgcatgca gtgatgccac tttgtataag ctatatacca gtaggattag cttgcggagt
    28081 attgttgcaa aaagttggat ttgatcctct cttatcagga ctgttatcga ttctggtctt
    28141 ttccggtggc gcgcagtttt tagttgcatc tatgcttacg acgcaagcat catttgcaac
    28201 gacattattg atggttttct ttttagaatt acgctataca ttattaggag caagtcttgc
    28261 cggttttatg aaaaaagaaa agcggacgtt tttggctgtc ttttctcaat cactgaatga
    28321 tgaaaactat gcggtgaact acttaaagtt ttcaactgac ccttcctgga ataaaagaaa
    28381 ggctttatat gtcaattggt tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa
    28441 ttttttcggc tcggtgattc gagtagatgc tgaccttgtc cattttgctt tgacggccat
    28501 gttcattttc atgtttatca tgcagatgaa aagcgcacta ctgatcttta caggtttatt
    28561 ctcaggcgta ttaggggtcg tattcatggt attattccaa aatactttcg gattgattgc
    28621 agcaacagtc attgcttcat ttgccggatt tatgctggag aaggcattca aaaaagaaaa
    28681 agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag ccgctcttca acttcccgga
    28741 acaggaggcc aatcaccatg actaaactat atttgctact tttagttgct tgtctgttca
    28801 tcgtggcata tatcccgcgc ttgttcccga tgctttattt tactcatcga aaagtgccat
    28861 cctggttcag tgactggatg aaatatgtac cggtggcatt atttgcggcg ttagctttta
    28921 aagatgtttt cattactcat gaacatctgg atattgcttg gaatatcaaa atagctgcaa
    28981 tgattctagt agcaggcgtg gcttacaaaa cacgttcgat ggcgttgtca gttttgacag
    29041 gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt tttattttat taaaaacaga
    29101 gattgcgaca taagttgttc aaactgatct atccgaactg catttgcaac agtcaattct
    29161 ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt ggcttatgat gcaagctctt
    29221 ttttatttta ggaattagag agggatttgt ccttctatga ttttttgcta taatagggaa
    29281 gatgtttatt ttatgaaaga atagttgagg gaatttaaat gaataaaaaa ttgatgcaag
    29341 gaacattttg gctaaccttt gctaatcttc tatgtaaagt tttaggggta gtctatttga
    29401 ttccctggct aagtatgatg gggaacaatc aagatggtat gcttgctacg acattgtata
    29461 atgttggcta tcttccttat ggattgttcc tgatgcttgg tacagtcgga tttccaaatg
    29521 cgattgcaaa aaaagtagct gtagccacaa aagaaggaga taacgctgct tgtcggctga
    29581 tttttagaag tacgatcaat atcatgtttg tcatcggtat cgcctctgct gcactgatgt
    29641 atttatttgc tcctttacta gccggaatca gtccgattgc taacgttaat aatgggatac
    29701 tagctatcag aagtttatgc ccatctttga ttgctatccc aattcttagt gcaatgagag
    29761 gatatttcca aggaaaaaat gatctgcggc cttatggaac ttctttgatt atcgaacagg
    29821 ctgtgcgagt gatcgttatc ttggctggta cttattactt gcgcgtattg actgacggaa
    29881 ccatattaga agctgtattg atcagtacag tcgcttcttt cttcggtggg ttagctgcga
    29941 ttatccatat gtatatcgtc ggacgcagaa aagacttctt cgaacttaaa gattttttga
    30001 tttccagccg ttatttcgaa agagaaaacc gatctgcctc tgtctctatc attcgggaaa
    30061 cactaccgtt tatttttgtc ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa
    30121 cgatgaaacc actgcttcac tttttccgtc cagagatcgc agatcagcaa ctggaattct
    30181 tattcagccg tgcttctgtc aatccaaata aattgacatt gatcctgatc tccatggtag
    30241 gaacagtagc tataagcagc ttgccaatat taagcacgat gaagaaaaaa gatcggatac
    30301 aaatcgaaaa aacagtagga gatagttttt cgattgcgtt attgattctt cttccttcat
    30361 tgactggaat gtctttatta gctggaccac tatacacatt gttttttggc tatgatcctg
    30421 aaagtgtcgg atatttccaa atggctttgc tagcttcttt gtttttctct ttattcacga
    30481 tcctatctac gatgcttcaa tctttgaatc accatcgttt tgcgatccga ttaactgtag
    30541 aagcaattat cctgaaagtc atcttccaag taatcggatt aggattagtt ggcggatacg
    30601 ggatgagctt atcaaatggc ttagcattcg gtattgtctt tgttcgcggc tatcacttta
    30661 tgtgcaaaga ataccgaata gcacctttag caaagatcag caattttttc ttaaaaactt
    30721 tccgctccac cctgattatg cttgcagtat gttttgccgt tttctttttg ctgaatcagc
    30781 gattgtcaat ggaatcaaaa agctatgcaa tgatttattg tgtggctgta ggaagtattg
    30841 gcggcttagt atttttattt tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg
    30901 ttaaacatca tagcagaagc aaagaatagg ttaactaatc gttttttgct gtcacttgaa
    30961 aaacggcaac tcgtatgatt acgcttgtcg tttttctatt ttccaatttt agtttcatat
    31021 ctaatcttac ttatgatata gttataaggt ctggaaaaat tctttgaaac gaggaaatta
    31081 aacacatgaa acttgcagta gttacagata gttcggcata tctgccggaa cgtatcaaga
    31141 accatcccga cttattcgtt attccaatcc ctttgattat ggatgggaaa atttataacg
    31201 aaggaatcga tatcgaagcg gatgaatatt atggactttt aaaaaacagt aaagattttc
    31261 ctactacttc acaacctgtc gtaggggaag ttttgggttt atatgaggaa ttgaaagaga
    31321 aagggtatga cacgatttta agtatccatc tttcttcagg gatttctggc tttgtcaaca
    31381 cattatttgc gatgaaagat gacatcagcg gagtaacggt cattccttat gactctaaga
    31441 tcactagtat gccgatggga cacatggtag aagctgcctt agacttaaat gatgaaggtc
    31501 agtcccttga tgaaatactt gcacatatcg atcgaatccg agataatacc tacgcttatc
    31561 tgattgtaga tgatttgaac aatttagtac gaggaggacg tttgacaaat ggtgcagcgc
    31621 tgattggcag cttattaaaa atcaaaccga tcctgacatt ttctgaaggg aaaattgttt
    31681 tattcgaaaa aatccgttca agtaaaaaag catttgctcg agctgaagaa attattggta
    31741 gaagaaataa cgaaatacaa ccgccagtca aactttacgt gatacatgca aataatttag
    31801 aagtagcgat tgcggagaaa gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa
    31861 ttggtcattt cggaccagtc attggtacac atttaggtga aaaagccatc ggcattgcca
    31921 tttcagcgca ataattcctt ttattcaaaa aacataccaa aaatattcca acatcatctt
    31981 ggactttcta catgttacta atgagcgtgt aaaagaacga gatggtgttt ttatttctat
    32041 caatgaagct ctttttcttt gcaatcctca cttcaatcct ctataatgtc gcatatagtt
    32101 tagtaaatga gtaaactact aatttactta tttactaaaa ataaaaggat gaggagttaa
    32161 aataatggaa ataccaacaa atttaaaaca taaaccagta atcgttgtag aagactatga
    32221 taaagttgat ggaagaaatg cattaaatac ggatgcaaaa gggctttcac tgggccttgc
    32281 tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag gtatggcgac atactggaga
    32341 aaaatggtca cgacagtcgg aagaattacc aatcacacgt attttagatt tagcgatctt
    32401 agctgcacaa ggaagtttat acttccaaga tgcttatcgt tatgaaaaat tttatgatcc
    32461 agaaaatcca gtcgtagaca tcattggatt acaagggaac cgaatgacgg tagaagtaga
    32521 taccaaaaat ccaaagatcg atgaagacat cattttgtat tacgatacac tacaaaaaga
    32581 cggagaactg attggggaac gattccgtat tttaaaacgt cttttagatg agctaggata
    32641 ttaatagaca gagatgatca aaaggggaag agaagcatgg agaatttctc actaacagaa
    32701 aaccgaacct tttcacggct agaaaagcaa atgatctgga agaaaccgaa aagccatcgg
    32761 acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag ggaattggca agatcctgaa
    32821 atgaaaatca gtaacgtact tttggaagga gatgccgggt cggggaagac acaattagcc
    32881 aaagcactat ctgctgatct gcaacttccc tatacaaaag tgacctgttt tgcagatatg
    32941 gacaaatcag atgttttcgg agccttatta cctgtagtag attctaataa ggaacaagac
    33001 caagaattac tagaagctat ttaccaaaca gatacacttg aagctgtact gacactgatc
    33061 cagaaccatt acggcattga tcctttttct gctaaagaaa aattagcaga gctagttcaa
    33121 aggatcgaag ctgattatcc agatgcaatc cattacagct attacccttc tgaaatcgtt
    33181 cgagcgattg aaaaaggata tttattagag attcaagagc cgactgtcat ccgagatgcc
    33241 tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg ggatgttgaa tttaccgaca
    33301 ggaatcattc gtcgccatcc agattgcgtc attgtgatca ctacaaatcg aaattaccaa
    33361 ggaaatcgcc cattaaatga atctttaaga gatcggatgc aacatgcgga aaaaatggat
    33421 cttcctgcct tagaagtcat ggcagaacgt gcgatggcga aaactatgat ccaaaaacaa
    33481 gaacttctct taaagatggc agagattatc cgtttgttgg atgaaactgc aaaagctaac
    33541 gccatcaaag gtgtagcagg aatgcgttct tatttttatt gggcaaatac ctataagcaa
    33601 ggacaagatt tactccagtc gatttatcca aaagttttgt ataaattatc cactgattca
    33661 gatgaattgg caattcttga acaagctttg tctgacagtg gattgctact ggaacttcag
    33721 gacatattga gaaaagaaaa atggggtcat cctcaatctg agcatacaaa aggaagaacc
    33781 attagcgccg aagaagcaaa tgaacgaaac atcactgaaa atgctgaaga aattctgcgc
    33841 ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg agggagaaga gaaacaagaa
    33901 gaaacaatag aaaaaaacga gattcctcct caaatgcaaa aagaacgcag tagcgatatc
    33961 gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt ctcaagaaat gtctgcttct
    34021 gacatggaag cacatgataa ggaaatcaag aagcaactga ataaagaagc gcgacaaatc
    34081 atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc accgaccagc tttccaagga
    34141 aaaacgccgg aagcacgtga gctacacatg caagtaatgc caatagtaga atcacttagc
    34201 cggcaaattt tagagttact ggataatgaa caaacagaga cgtaccaaaa aggaaaatac
    34261 gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg atttgagaaa ttttgacaaa
    34321 aagaacccgc cacatgagca accttcttta gcggtagctg tacggatcga tgaatctggg
    34381 tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag cagcgattgc cattgccgaa
    34441 ttttctaaga aagtcgatat cccattgttg atttacggag atacagcaga ccgttcgtca
    34501 agagaaaaga cttctttgtt ttcttataaa gaatttgaag acggatttca atggttaaat
    34561 gaaaaattag tcactatgaa accaaggcaa aacaatcgtg atggtgctgc acttcgttta
    34621 gcagcagaaa aattaaacag acaatccgca acaaccaaac tgttgcttaa tattagtgac
    34681 ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag caaaagaaga tatccagtct
    34741 gttttgaaag aatatgaacg tcaaggaatc ctatttgtct ccgcagctat tggccaagac
    34801 aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg tagatattac tgacttgaat
    34861 gaatttccca agcaaatgat tcaactgatt gcccgctatc tatgataaaa taaagctcaa
    34921 cgaacgcact tagcagattc gttgagcttt tcgtttctag ttaccggtaa caaggatact
    34981 tctaaaatag aatcggttat aatcaagagg gaccgttaaa ggagtgaaac gatatgatac
    35041 aagaacaaaa atggtggaaa gaagcagtag gctatcaaat ctatcctgct agtttcaaag
    35101 atagcaatgg cgatggtcaa ggagacatca atgggatccg tgaaaaactt aattatttga
    35161 aagatcttgg tatcggcttt atctggatca atccgatcta tcaatctcca tttgtcgata
    35221 atggttatga cgtaagtgac tatcaagata tagaagagag attcggaacg atggaagatt
    35281 ttgatttatt gctaaaagaa gcacatgaat tagggatcaa agtgattatg gatcttgtca
    35341 tcaaccatag ttcggatcag catcaatggt ttgaagaatc gaaaaaatct aaagaaagcc
    35401 cgtatcgcga ttattacatt tgggtcgacg gggtagatgg caaagaaccg aataattgga
    35461 catcgatttt cggcggttct gcttgggagt attctcatga aactggacag tattatctgc
    35521 atgtttttgc aaaagaacaa ccagacttaa attgggaaag cgagaaattg aaagaagaac
    35581 tattcaatat gatccgatgg tggttggata aagggataga tggatttcgt ttagatgcga
    35641 tttctcatgt aaaaaaagat gaatattcag taaaagccac agagaaccct ttctcaccct
    35701 ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt gaaacatgtt tttgaagagt
    35761 acgatatcat gactgtcgga gaagcaagtg gtgtcactgc agaagaagga ccacaatggg
    35821 tagggaaaga cggttatttc gatatgatat tcgaatttga tcatatccat atctggcagc
    35881 aagaaaaaga agggcaatta gatgtcctta aattgaaact tgcattaagc gcttggcaaa
    35941 cttcattgga tggtatcgga tggaacgctt tatatatgga aaaccatgat gttcctcgtg
    36001 ccgtttcagt gtttggagat actcgtcccg atttttgggc tatgtctgca aaagcaatcg
    36061 ctatgatgta tttctttttg caaggtacgc catttattta tcaaggacag gaaatcggaa
    36121 tgacgaatat gccctttgaa tcgatcgatc aagttgatgc agtagattcg aaaagacttt
    36181 ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc attggatatc attcgtgaaa
    36241 caacgagaga caacagcagg acacccatgc aatggacttc ggaacaatat gctggttttt
    36301 ctacacatga accttggctg atcactaatc caaataccaa aacgatcaat gtagaacaac
    36361 aagaatatga accagagtcg gtcctgcaat tctataagaa catgatccgc attagacaaa
    36421 ccaataaagg tctgatatac ggttcttata aagaatatct tcatgaacat ccacaacttt
    36481 atgtctatga aagatattta gaagatgaac aatatcttat tatggtaaac ttaacagaat
    36541 cacttgctga ctatgaactt ccaaaagaag cagatcagtc ctggacatta ctcttgtcaa
    36601 attcctctag cggagaattt gaagctaaag gcatactagc accttatgaa gctcggttat
    36661 ataaaacaaa caagtaaaac ttcctcgtta aagttcatta gttggacttt gcgaggaagt
    36721 ttttcagatt gctctgtcaa ttactcattt caataattcg ctctaggacc accgatatat
    36781 ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa gggttttcaa acgaggtctg
    36841 acaggtactt ggacatgttt gatatgcata ccgattgatg tgtcaccgat atcgataccg
    36901 gcttgtccaa ctacgtgttc cacttcgaca ggatcattga actggtcaaa agcagcaaca
    36961 gaacaagcac ctccagcatg tagtgcagga acaacagaga caatttcgaa attttttgct
    37021 tctgccactg ttcgttctac tactaatgct cggttcaaat gttcacaacc ttggacagct
    37081 agcgcaattt ctttaggatc caacaactct tttaacgtac ggatgatcca ttgaccaact
    37141 tccgcactgg aattttttcc aatatgtcct ccaacgactt cgcttgtgct gcatcctaaa
    37201 acaaaaagat cacctttttt caagtgtgcc tcagccaata tgtcattaac tatttcagtc
    37261 aattggtctt ttaattcttt ttctgacaac ttcattttct aaaaccttct ttttcaatta
    37321 atattgcttc cgtgcttgaa tacgttgaag acttgcagtt ataggaaagg caagtcccat
    37381 tccaatcaga ttttggaaga tgtttcctgg tatagaagcc actccagccg gccaatcata
    37441 taaaatccaa ccggcgatac catagccgat gatcataact aagcttccta ataaaagccc
    37501 taatccccac atacgagtag aagatttgct gaaagaacca gcaacatatc cttgtaaccc
    37561 gtggatcact aatgaaaaaa ctgcccactg cggatatcct gaaatcaaat cgatcaatag
    37621 accactggaa gcaccaacaa ctaatccacc cgttggacca taaagaaaag cagcggtata
    37681 gatcccggcc tcgcataatg tcacaaatcc attcgtagcc ggtacaggga tcaaaattgt
    37741 taatgaaagg gcaactgtca acgcaatcag catagcatag atcgttaatt gcttagtttt
    37801 catttctcat tcctcctttt tgaataccgc cagaccagac acttccggta tgatcgttca
    37861 tcagcacgcc attagaaata caatgggcaa caaatttttt actttctgct actgctttgg
    37921 taaaatctgc ccctaacaca agattcgctg ttattgcaga agaaaaggca caaccggccc
    37981 cgtttactgt tgtagtgtcg atttttttat gagaaaatac ctcataatga tcaattgaat
    38041 agagaagatc cacagcttca tctccagcca tccttgtgcc gcctttgatc acaatgtttt
    38101 ttgttcctga agcagtgagt tctttagcga gatggatcat ttctgttaac gaagagggaa
    38161 gagcttgacc agaaagtaaa gcagcttctg ccaaattagg cgtaatcatc gtaacaagtg
    38221 gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt gatcacagct tcagtttctt
    38281 tgaatgccaa aacagggtct aaaatgattg ggatattttg ttttgttttt atgaagtctc
    38341 gaacaaccat gattgcttca cttgaattca ataacccaat tttgatacca tctaatgaag
    38401 tcattttatc aatcgaaact aactgtcgtt taagcaattc caaagatata gattccagca
    38461 taaatcgctc attaatatct agtgccccta tagaagtcaa ggcgcttagt ccgaatagac
    38521 caaaattctc aaaagttttt aaatctgttt ggattcctcc accagcaaat ggatcagaac
    38581 cgccaattgt caagattctt ttcataacat tttcctccat gaataagagt ataacgaaat
    38641 tttcaaaaaa gaaaaacagc caattggcat atttttatct catccaattt aaaaaaacaa
    38701 aaagaaaaga aagaccaaaa tggatctttc tttccttaaa tagttaggac ttttgtgatt
    38761 ttaattcttt ctcgatttga agccgttgca ctttcattgt agctgtccgc gggattgcat
    38821 caaaatcacg gatgataggg acgttcaagc gaggaagttc atggacttgc tcccaccatc
    38881 gattccaatc catttcttta tcaggagcta aagcaataat cggttgtgga gaatgatttt
    38941 tatcccttac aatcactact tctgccaaaa aatctaacga atctaataaa aagtcttcaa
    39001 tagctaatgt actattgatc gtttcgatca aatccacttg ccgatctttc aaaaataggt
    39061 ggccatgctt atccataaaa ccgtaatctc cgctatccca ccaatcgcca taaacatttt
    39121 cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg tcctttagac agtaattgta
    39181 tatgaccatc tgtgttttca ggtaggacat tcccaactga atctgtaatc cgagcgcttg
    39241 tcatgtcttc cagtccaacg cccatatctc ttgcatcact tgttttcaaa ctctctagtg
    39301 tatgagcctt aagaatcatt ggtccgcatt cactttggcc atatacttga agaaataccg
    39361 catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt ctggttgttt atagcatcaa
    39421 aagtggagtg atagtatcgg atacccgaaa aagcttctgg atgctcctta gcagtaaaac
    39481 gccactgaac aaagttattc ggatgggtct ctagtgcaat tggccggtga gcttccaaca
    39541 tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat cataggaaat cccatggaca
    39601 tcaaagaaga gataccaata ttgaatctgg aatgcactgg agagatgtga aaagcgatta
    39661 atttcttttc cgaaattttt gtgaaaactg ttttttgcca tttcgtccgc catcccatag
    39721 aatgagcaga atgacaaata agtttaggga taccagttgt accagaagta tgggtcatat
    39781 aagaaatttc atttttgtct aaaaatgatt gagaaacaga caaagcaggt tgttccatta
    39841 aataaagaat agga
//
LOCUS       DACGLI010000026        37393 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.027, whole genome shotgun sequence.
ACCESSION   DACGLI010000026 DACGLI010000000
VERSION     DACGLI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.027"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(128..775)
                     /locus_tag="IXT22_001411"
     CDS             complement(128..775)
                     /locus_tag="IXT22_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAQ4862787.1"
                     /translation="MEKTIKPYQYYFIKREVEQLLSAYSSVNDPKTVQTVQALAAEKI
                     HEVLGHPNTAVNEFMEKVLDVTLKKEKAERLLEELKVIVLPFIQPTKPQIDKLFRKVK
                     KLKQPDWNQLDLREHTYIGWNDPGSQKKFMIYYEEEKLKGISGTLSPTINKGICSICQ
                     RTSNVSLFLSTTKTGSDGTYTKKGNYICHDSDQCNQQLVQLAPFYEFTERVKRER"
     gene            complement(1040..1543)
                     /locus_tag="IXT22_001412"
     CDS             complement(1040..1543)
                     /locus_tag="IXT22_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4862788.1"
                     /translation="MTEKWREDEEYMSYINDLLETDAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYKLAKKWGGDARATARAGLLHDLFYYDWRTTKFDEGTHAYVHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMTASMKQKWQRY
                     FGKEQSI"
     gene            complement(1667..2431)
                     /locus_tag="IXT22_001413"
     CDS             complement(1667..2431)
                     /locus_tag="IXT22_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAQ4862789.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKGEYLLEGFHLIEEAVAS
                     NAKVNELFITQRGLTEWASWLEENQALSVTLVSEEVMATVSDLPTPQGIMAVVEAEKR
                     EIPNFEGGWLLLDNVQDPGNVGTMIRTADAFGLSCVVLGKGTADVYSTKVLRSMQGSN
                     YHLPIIQEDLTKLLPILKEQGFITYGTELNEEAVSLNDIQTTENYAIVMGNEGQGVRP
                     EVLALTDKNVYIPIQGNAESLNVGVAAGIMLYHFSV"
     gene            2539..2814
                     /locus_tag="IXT22_001414"
     CDS             2539..2814
                     /locus_tag="IXT22_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAQ4862790.1"
                     /translation="MNKIKMNVQGRVQSVGFRYMTKIVADQLGITGTVKNEDDGSVTI
                     EAAGDDEAIKKFVEEVKRSPSPSGRVQYVDLQENPMMEDRKKFVVIG"
     gene            complement(3162..4313)
                     /locus_tag="IXT22_001415"
     CDS             complement(3162..4313)
                     /locus_tag="IXT22_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4862791.1"
                     /translation="MDKSKIARRFQQPAENLLMNIAILAKEKEDIIDLSIGDPDLITD
                     PTIIEAAYTDVKNGATNYTAPDGSKEFLSTVVDFYQKKYGLSVECNQVRATVGAMHGM
                     YLVLQALLDPEDEVIIHEPYFSPYREQVILSGGKPVFVPTYEEKGFQLDVEDLKAAIT
                     DRTKVIVINSPNNPTGAVFSESTLKKIAEVAIENELYIISDEIYEDFAFKEKFVPMAR
                     FAPDNTITVSGVSKGFAMTGWRLGYMIAPAYINQIAGLINENITYSAPTASQRGAIYA
                     LKHYEQLVPPVVEVFKERLAYIEKRVAEIPYLSLSSVSGSMYAFINISKSGLDSVTFV
                     EEVLEKSGVLFVPGKAFGETIGDNYIRLAATQPLEILGEAFDRLAKLNF"
     gene            complement(4333..5055)
                     /locus_tag="IXT22_001416"
     CDS             complement(4333..5055)
                     /locus_tag="IXT22_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862792.1"
                     /translation="MLNVKKLSKSFGENEVLKSIDLSVKEGEVVVIIGPSGSGKSTIL
                     RCMNLLEEPTSGEIFFKGQNITAPDSDINQIRQKMGMVFQSFNLFPHMNVLENLTITP
                     VKIKKEDPKKAKEHALSLLNQVGLKEKVDSYPTSLSGGQQQRVAIARALAMNPDVMLF
                     DEPTSALDPEMVGEVLAVMQDLAKKGMTMVVVTHEMGFAKEVADRVIFMADGIIQEEG
                     TPKEIFENPQNSRTQDFLNKVL"
     gene            complement(5048..6499)
                     /locus_tag="IXT22_001417"
     CDS             complement(5048..6499)
                     /locus_tag="IXT22_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HAQ4862793.1"
                     /translation="MKKGINILLVALMFLLVFLPVKVQGAEKDEIYERIKQSGELVVG
                     LSADYAPYEFHANVDGKDKIVGFDVSIAEKIAKDMGVKLKVEELGFDALLGALKTGKI
                     DLVISGMAVTEERLQEVDFSDPYFVVQQKVLVRKEDKNKFKTTADFSGLAVGAQKQTT
                     QEELVKNELTGAELTSLQKVPDLINNLLNEKVEGVVLEQPVAEAYAQQNKKVALTPVK
                     FAQGEKTTAIAMSKNTPELKNHVNASIKTINDDGLLKDYQKQANQLMFQDDQSFLQKY
                     GPYYLIGTKYTILLAFVGVLFGMVFGSLLALMKLGKNKFLKALAIIYIEYVRGTPLLV
                     QIFIVYFGTGVLGLDLSKLVAGCIAVSLNSAAYVAEIVRAGINAVNKGQMEAARSLGM
                     DQKEAMRFIIFPQAIKNILPALGNEFVTIIKESSVVSVIGVSELIFQTGVVQGASFKP
                     FLPYVLVSLIYFVLTFSISRILALVERRMGLNA"
     gene            6641..7723
                     /locus_tag="IXT22_001418"
     CDS             6641..7723
                     /locus_tag="IXT22_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4862794.1"
                     /translation="MTKNLIVRGAPQEYEIKENAWDSLPEHLYKRHIDNVLILHGKTS
                     WKAVKDVFPDLSITKIFEYYGGECTDPLADSFVSLCKKKDFNGIIAVGGGKVADLGKL
                     IAYKTNLPIIILPTLAATCAAYTPLSVVYNEEGVMLRYDMFPKANDLVLIDPKIILHS
                     PREMMIAGIGDTLAKWYESHAIISQLTIKPIEVQVAEFAALRCREILLEKSAEAMEAM
                     DQQKINQAFIDVVETNILLAGMVGGFGDDYGRTAGAHSIHDAMTVLPDSHQQLHGNKV
                     AYGILVQLMIENKLAEIEHLLPFYHHLNLPTSLADMGLHLTESDYQAVAERACLPDEM
                     IHFMKETITPALVVQKMKELEQVTQG"
     gene            8057..8995
                     /gene="yidC"
                     /locus_tag="IXT22_001419"
     CDS             8057..8995
                     /gene="yidC"
                     /locus_tag="IXT22_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4862795.1"
                     /translation="MNKWKNWLLGSGLVTIMLFLSGCVRMDSNGNPDTSGIIYRILVH
                     PMGQAITYLVENFNWSYGWAVILMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     ATQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESTFYGIDLGNPSLVLVAIAGIAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGIFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTPAEPAKQTKKQVQAPKNNAKNGRNAGKQQKRK"
     gene            complement(9176..9580)
                     /locus_tag="IXT22_001420"
     CDS             complement(9176..9580)
                     /locus_tag="IXT22_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4862796.1"
                     /translation="MSRQLVLISHGKFCEELKNSTEMIMGPQENIYTIPLLPEDGADT
                     YKERFLSVTAPLKDYVVLCDLLGGTPANTVSKLIMEGETIELYAGMNLPMVIEFINSQ
                     MIGAEPDFIGSGRESIVSVNQVIAGMGDDEEE"
     gene            complement(9596..10405)
                     /locus_tag="IXT22_001421"
     CDS             complement(9596..10405)
                     /locus_tag="IXT22_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4862797.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDDTPELKEMMKTHTQFFNTSNFFNTIITGIDLAIEEKEGVSSKETVSGMKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPVGILIWILAQVAVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKLLPAGIVGGVYWMLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(10392..11282)
                     /locus_tag="IXT22_001422"
     CDS             complement(10392..11282)
                     /locus_tag="IXT22_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4862798.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLKAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDQHVETMNYKAIERNFLMGALPWALSRMVPVFLAL
                     AFGGGLVQNVVAVLNGDLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHISYLILGFT
                     ITALLATVFSNVQLLGTSVASVVKDFPGTFNSLPMLAVALIGLALATISYKNDQKNDQ
                     HPVVSQQSQSDEGEIEDDEI"
     gene            complement(11295..11774)
                     /locus_tag="IXT22_001423"
     CDS             complement(11295..11774)
                     /locus_tag="IXT22_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HAQ4862799.1"
                     /translation="MAIIGVRIDGRLIHGQVANLWTTKLNIGRIMVVDDEVATNAIEK
                     SGLKLATPAGVKLSILPIEKAAANILAGKYDSQRVLIVAKKPDRILALVEKGVPIKEL
                     NVGNMSQTDETRSITKSINVVDADVEVFKKLDQLGVHLIAQMVPNDKAEDFMSLLIK"
     gene            complement(11791..13557)
                     /locus_tag="IXT22_001424"
     CDS             complement(11791..13557)
                     /locus_tag="IXT22_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HAQ4862800.1"
                     /translation="MTRFEIKEEFLLDGQPFKILSGAIHYFRVHPTNWERSLHNLKAL
                     GFNTVETYVPWNLHEKEEGTYDFSKILDLSHFLELAQSLGLYAIVRPAPYICAEWEFG
                     GLPAWLLTKECRIRSADPRFMKYVKRYYQTLLPKIVPHLVTHGGNVLMVQVENEYGSY
                     GEEKAYLRQVKKYLEEGGIDVPLFTSDGPWQATLRAGILIDDDVFTTGNFGSKAKENF
                     ADMAQFFEAHGKKWPLMCMEFWDGWFNRWKEPIIKRDPEELADAVKEALQIGSINLYM
                     FHGGTNFGFMNGCSARGAIDLPQVTSYDYDAPLDEQGNPTEKYFALKRMMAENFPEMQ
                     QMEPWIKETIVKKGINLKEKVSFFATLDTISKPIHSTYPQTMEELGQNTGYLLYRTTI
                     KKDAVNEKLRIIDGRDRVHVFLDEEKQAIQYQTEIGETIPLTLEKEDHQIDLLFENMG
                     RVNYGHKLLADTQRKGIRTGVMSDLHFITEWTQYCLPLETTEHIDFSKKWEAGQPAFY
                     RFEAELSEIGDTYLDLSEFGKGIVWVNGTNIGRFWEVGPILSLFVPEGLFRKGQNEIV
                     IFETEGRFSEVIDFVKEPIEKS"
     gene            complement(13603..14544)
                     /locus_tag="IXT22_001425"
     CDS             complement(13603..14544)
                     /locus_tag="IXT22_001425"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAQ4862801.1"
                     /translation="MITTVTMNPSIDIAYTLDELRIDQVNRVKTVNKTAGGKGLNVAR
                     VLHLLADDVLATGLVGGQHGAYIKEQLDQSGITHQFLPIKGETRDSIAILHGVNQTEL
                     LESGPVVTEEEQHKFTEHFARLMETTDIFTISGSLPQGFSKSYYAELLALTNKKGTRV
                     LLDTSGQTLLEVLEGKEKPFLIKPNLEELGELVHQTISSATSLDEIQSLLDHPLFEGI
                     NWIVLSLGAKGAIAKVGRHFYQVTIPKIAVVNPVGSGDSTIAGLAHALSKSYTIEETL
                     AFAMACGMANAQQEKTGWIDPVKVDYFRGEINVRKIR"
     gene            complement(14541..15536)
                     /gene="lacD"
                     /locus_tag="IXT22_001426"
     CDS             complement(14541..15536)
                     /gene="lacD"
                     /locus_tag="IXT22_001426"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4862802.1"
                     /translation="MNEEKIAAMKSLSTKEGIISALAIDQRGALKKMIKALGKEPTAQ
                     QITEFKELVSAELTPYASAILLDPEYGLPAAKARHQEAGLLLAYEKTGYDATTPGRLP
                     DLLADWSTLRLKEQTADAIKFLLYYDVDEDPEINHLKHVFIERLGSECAGEKRPFYLE
                     LVSYDAKTNDSTSLEYAKIKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVEGYSDG
                     EIAYSKKEAAAFFKEQSDATPLPFIFLSAGVSTALFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGREGAIEWLRTQGRQNIESLNKVINENATPWFDKVKEDSVTAK"
     gene            complement(15529..16722)
                     /locus_tag="IXT22_001427"
     CDS             complement(15529..16722)
                     /locus_tag="IXT22_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4862803.1"
                     /translation="MFELSKDKLKELGAEITTREIKQQPQLWKETAEILAQNQEKLAL
                     FFDQIKKAANGKRVRVIFTGAGTSQYVGDTAVPYLNEYGDNDHFIFHSFGTTDIVSSP
                     KEFLFPDEPTLLVSFARSGNSPESVATVKIANEQIKTLFHLTITCAKEGQLAKNAATD
                     ERNYLLLMPEKSNDAGFAMTGSFTCMLLSALWVFDQTAVEKKESYLQQLIRTGEDLIS
                     RDQEIQKLLPKSFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVIGFVNNQPYTRNYDLDILEEIKDDQITTSVIAIAQPGNIDFTGTSLLLE
                     ASISLPDAYLALPMIMTAQIIALDTSIKVANKPDTPSPTGTVNRVVKGVIIHEYVNKG
                     ETKDE"
     gene            complement(16740..17468)
                     /locus_tag="IXT22_001428"
     CDS             complement(16740..17468)
                     /locus_tag="IXT22_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4862804.1"
                     /translation="MESSSKGKSLYYQLVDVLKERIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELETQGYIYRRHGKGTYVSDLSDKSSDLAGAYSFTEEMRELGRVPNTV
                     ILEFKQMEANKKVAKNLNINLGETVFKLKRLRLADDEPLMVERSYLPAKLFIGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDADPLRIADGAPVLYLSRTTYNVKN
                     EIIEYTDSVARADQFHYKIRHVRK"
     gene            18306..18572
                     /locus_tag="IXT22_001429"
                     /pseudo
     CDS             18306..18572
                     /locus_tag="IXT22_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18545..18739)
                     /locus_tag="IXT22_001430"
     CDS             complement(18545..18739)
                     /locus_tag="IXT22_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862805.1"
                     /translation="MGQKCLTPRNKKKFTKIAFQIFVNFGLFPKELLLLPPFTRESVA
                     KLIFRFIPHSSVYLVKNVLP"
     gene            complement(19955..21121)
                     /locus_tag="IXT22_001431"
     CDS             complement(19955..21121)
                     /locus_tag="IXT22_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAQ4862806.1"
                     /translation="MKISVFGLGYVGLANSLLLAQKEQVKAYDIVEEKITMLQNGISP
                     IEDKEVHEFLKRDDLNVEFTSNFTDAVNFGDYLIIATPTDYDEKKNYFNTSTVEDVIE
                     KALAIRPDSTFIIKSTVPVGYANEIKAKFGTENIIFSPEFLREGKALYDNLYPSRIIV
                     GECSARGREIATMFQRNAFNKDASVLLTHSTEAEAIKLFSNTYLALRVAYFNELDTYA
                     EFRGLDSKQIIEGVGLDPRIGSHYNNPSFGYGGYCLPKDTKQLRANYEKVPSNIISAI
                     VDANTTRKDFIAGQILAKKPNVVGIYRLTMKAGSDNFRYSSIQGIMKRIKAKGIEVVV
                     YEPTLDEDEFYHSQVLKDINEFKNISDVIVSNRFEDILKDVEEKVYTRDIFGDN"
     gene            complement(21209..21637)
                     /locus_tag="IXT22_001432"
     CDS             complement(21209..21637)
                     /locus_tag="IXT22_001432"
                     /inference="COORDINATES: protein motif:HMM:NF012360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAQ4862807.1"
                     /translation="MIFGKKHSLVEVPEFGSEPYLIEIGDNFRCSFGVKFITHDGGVW
                     VLRKMSSVSESTSKIGRIKLGNNIFIGIYSIVFPGVSIGDNVIIRANTLVNKDIPNNS
                     VVAGSSCKVISTIEEHYEKNKNEFIKYRTSMILKQKNFFY"
     gene            complement(21723..23147)
                     /locus_tag="IXT22_001433"
     CDS             complement(21723..23147)
                     /locus_tag="IXT22_001433"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014051.1,HMM:NF026018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4862808.1"
                     /translation="MDSSSNKSHSIAKKAFIYAIGTLSSKMISVIIIPIYAVYISVAD
                     LGSFDYQNTIAQFLSPVIFGAIWEAILRMGLGKEKNIQKKVVTNSICFVIANTVILAI
                     FLPIIYRMIFPNLEYYQLFVFQLIFTPILSVFQYIVRALGESKIFVMSGIIAAGINLL
                     LLTIFVVTMGMGILGLLLSIIISNVINLIFLIFRGQIFQYFATSSFDFLFLKSMLKYS
                     IPLTLNLTFGWLIVGFSRFYIGTYIGVTENGIFSFAMKFSSIILTLTSIVSMSMIEDA
                     VITSENDDFIERFVEKNTYIFKMYIRLATLSIPIICCAYSFITNPDYKKSLVLVPILV
                     IMACFSGMTTNIGNIFAVYNKTNQLLMISVVSGLLSVVGTYLLGYSFGVIGVSFATLL
                     GTLVLFGLRYYFGRKIAYYAFDWKRISLLLVLYSAIAFVCIHRGFYFNLFLTIIFSAI
                     FVFTYKQLIITYLKKFFRIKMAKR"
     gene            complement(23515..24531)
                     /locus_tag="IXT22_001434"
     CDS             complement(23515..24531)
                     /locus_tag="IXT22_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003512346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HAQ4862809.1"
                     /translation="MKMKILITGGAGFIGFHLSRKLLKETENQIVAIDNLNDYYDVQL
                     KEDRLTILYDYNNFKFIRMDLLEKEKLDSLFESEGFDIVIHLAAQAGVRYSIENPYAY
                     IDSNIIGFLNILEACRNFPVKHLLYASSSSVYGGNTKVPFSTEDSVDHPVSLYAATKK
                     SNELMAHTYSHLYKIPTTGLRFFTVYGPFGRPDMAYFSFTKNILSGKEIKIFNHGKME
                     RDFTYIDDIVEGITRLINKVPEPNSDWTDIDDLSSESWAPYKIYNIGNNKPVALLEFV
                     ETIEKYLGVKANKIFLDMQPGDVVRTYADIEDLEEKINFKPNITLDEGIKKFVEWYTV
                     YYLS"
     gene            complement(24777..25715)
                     /locus_tag="IXT22_001435"
     CDS             complement(24777..25715)
                     /locus_tag="IXT22_001435"
                     /inference="COORDINATES: protein motif:HMM:NF016640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF616 domain-containing protein"
                     /protein_id="HAQ4862810.1"
                     /translation="MGRQELYSLAINELEKRNLEIHELNQKNNSILGMKIRNKINQLN
                     QMKKRDNLLPAKYTLKSMTGKGPIKDYSNRENRSDELRKKELTNQGTPKRIAVYSCIT
                     GNYDSIKEPDFSHPLVDYYLYTDNVITSEHWNIREIPKYISELKNNILINRYIKFHPN
                     ELFTDYDFTLYVDGNVTITSDITGLLNSSSKLGLSMHKHSERKSLYSEADALIAVGKG
                     NKESIIEQISKYREEGFPDNFGLAEATVILVDLNNSIAENLLDLWWREYLNSESGRDQ
                     LAFPYVLWKSGHAMKEVTTLGNNVYKSAKLRIISHY"
     gene            complement(25752..26843)
                     /locus_tag="IXT22_001436"
     CDS             complement(25752..26843)
                     /locus_tag="IXT22_001436"
                     /inference="COORDINATES: protein motif:HMM:NF026247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpsG family protein"
                     /protein_id="HAQ4862811.1"
                     /translation="MDTEASLEINQEKSVSQKKWSTSNKILSGVLLLIMWIIMAFNTQ
                     NADYYAYSVLYNGIAQFGMDFSSDSIEPGFRAVMYVCTFISSQYQIFLLIISTVLLSA
                     LLYVIRLFTTNVFLVLFLFFIFGFTSQAIQVRMFSALIFILLAFYHLTKLRGSKAIFK
                     YIFFILVAGLFHNLAYFYLPFFIVKINKKITGYVTILSLLLFSIGQSYISSIFINTKY
                     DAYFDRNSTSISHVVMFALFFSANLFLVHKLSKMNIYEKKVISLSSYIFSINMLASTS
                     IVFLLISNNFIRIIQNIFVLNYIIYASVLMSNYKRTKVKNYIYLLAYFFFIIVCLIFI
                     NIRGTAFVNGILPLFRENIIFKAVYYFFE"
     gene            complement(26815..27711)
                     /locus_tag="IXT22_001437"
     CDS             complement(26815..27711)
                     /locus_tag="IXT22_001437"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4862812.1"
                     /translation="MKNKIGIIIVTYNPDNNIKLLVDTLIQEKQNKLIIVDNGSDNIN
                     SFQFEMMENLILKKMNENIGLATAQNIGIEIAKKEKCDYILLLDQDTIIQKNLSLKLL
                     EEFTNIEAKDKDIGIIVPNYFENSNDESVSFTCKNERGRYVKKHFASTSGSMKIAFAN
                     SSGMFFKSELIDDVGNMKDEFFIDQIDVEFCKRVANNGYNIYVTNQVYFYHHVGDGEN
                     LKIGSKKIKIDNHNSTRKYFIARNSTLVKRMYKSDKEFSRLMNKRLLKFFIAIAFETD
                     KLSRFRAAIRGVRDGYRGVIGD"
     gene            complement(27701..28861)
                     /locus_tag="IXT22_001438"
     CDS             complement(27701..28861)
                     /locus_tag="IXT22_001438"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4862813.1"
                     /translation="MSENKKKWLLIHPFDYISRTNILEEILTENSIEYFNVVSDYSHI
                     RKQFLSSKERHMIKNRHVIKTIGYKKNISVMRILSHIWFSIKTLLFIRKEKPEIIYCR
                     IPPNTLVFFIAKFSRCNRVIFDVYDLWPESMPGIGNKYKFFTDLWKKLRDQYLSNSSL
                     VITECDYFKKFIKISGESKNMTIYPCSFNVDDQNDYGEKIVNKSLESTLNLAYLGTIN
                     NIVDLEAINELLKTCKRKFGNKINLYFIGKGESKTKLADICEKNHIEFVDCGVIYDNA
                     EKKVILDKCHFGLNLFKSNTIIGLSLKSIEYFRFGLPIISNLSGDTKEIVKRYNVGIN
                     YNSTVDENEMLKFYQCNKNINENVRKIYATIFSEQVLKMKWNEVYKVMNDEK"
     gene            complement(28854..29468)
                     /locus_tag="IXT22_001439"
     CDS             complement(28854..29468)
                     /locus_tag="IXT22_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_065828827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4862814.1"
                     /translation="MYEKFFKRLIDILFSILGLIMLWPLMTFVAILVRIKLGSPVIFK
                     QQRPGKHEKIFLMYKFRTMTDQRDEEGNLLSDDIRLTQFGKILRSTSLDELPELWNIL
                     KGDMSIIGPRPLLVEYLSLYSNEQRKRHFVRPGLTGLAQVSGRNAISWKEKFEKDIEY
                     VENISMMKDIKIFFLTLKKVIVRDGITSVASGTTEKFEGAKIDE"
     gene            complement(29476..30594)
                     /locus_tag="IXT22_001440"
     CDS             complement(29476..30594)
                     /locus_tag="IXT22_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAQ4862815.1"
                     /translation="MENKRILLASPHMSDEGYEQEYVKEAFDTNWVAPLGMNVNGFEE
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPIIYQGAIPV
                     FVDSDYETWNMNPEHLRTALEKYPNAKAVLVVHLYGLSAELDEITKICKEHNVVLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITVKGINTNHLIDELDKNNIEARPIWKPMHLQPVFDKYEYIGT
                     DVAQTLFEKGICLPSDSKMTDDDLYRVTNTIKRVMQNV"
     gene            complement(30596..31228)
                     /locus_tag="IXT22_001441"
     CDS             complement(30596..31228)
                     /locus_tag="IXT22_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4862816.1"
                     /translation="MKAIIVGAGGFGKEIAFLLESFSRYELIGFVDDSLKMQNQELVG
                     KTVLGTIDSLLELEEETAIFLGIASPDIKEKIYQKINKNNKLIFPNLVASSALVGINV
                     QLGIGNILMPYTTYTADVVLGNFNMINIGSTIGHDTQIGNYNSIFPSVNISGHVLLGD
                     KNEIGVGTKIIQNLRIGNMNIIGAGSVVIKNINNKTKNVGVPTKVIERWD"
     gene            complement(31239..33056)
                     /locus_tag="IXT22_001442"
     CDS             complement(31239..33056)
                     /locus_tag="IXT22_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4862817.1"
                     /translation="MFVLTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFGSLSASAASSIIILLFINKQYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYLSTDSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVIGFVDDDPNKRNTYLSGKKVLGSLKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESAHVKVNTMPSMEELASGKISVSKLKTIDVVELLGRDEVELDIESI
                     KDQITNKVILVTGAGGSIGSEICRQIIQFDPAKLLLLGHGENSIYLIDRELRTHHQKC
                     PTEIVPIIADIQDRKKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPVTVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSMQTVMEFVKSLPQDDEQLAKDIVTFANASNK"
     gene            complement(33069..33833)
                     /locus_tag="IXT22_001443"
     CDS             complement(33069..33833)
                     /locus_tag="IXT22_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAQ4862818.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLQLGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVAQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(33861..34559)
                     /locus_tag="IXT22_001444"
     CDS             complement(33861..34559)
                     /locus_tag="IXT22_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAQ4862819.1"
                     /translation="MARTQKQKATQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSRDAGYYYGN"
     gene            complement(34571..35350)
                     /locus_tag="IXT22_001445"
     CDS             complement(34571..35350)
                     /locus_tag="IXT22_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAQ4862820.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(35366..36310)
                     /locus_tag="IXT22_001446"
     CDS             complement(35366..36310)
                     /locus_tag="IXT22_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4862821.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(36356..37135)
                     /locus_tag="IXT22_001447"
     CDS             complement(36356..37135)
                     /locus_tag="IXT22_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862822.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT        11229 a         7592 c         5962 g        12610 t
ORIGIN      
        1 aaaggggtag ccccgtttct ttagtaggcg tcattagtta tcttacgatc aacgtttaaa
       61 ggcgaacacc atcacctatt cacttcacca aataagatag catatttttc agaaaaatac
      121 aatgaaatca ccgctcacgt ttcactcgtt ctgtgaattc gtaaaaagga gctaattgta
      181 ccaactgctg attacattgg tcactatcat gacaaatata atttcctttt ttcgtgtatg
      241 ttccatctga accagttttt gtggtagaaa gaaagagtga aacatttgaa gttctttgac
      301 aaatcgaaca aattcctttg ttgattgtag gagataatgt tccactgatc ccttttagtt
      361 tttcttcttc ataatagatc ataaattttt tttggctacc tggatcattc caaccaatat
      421 aagtatgttc ccttaaatcc agttgattcc aatctggttg ttttaacttt ttcacttttc
      481 ggaataattt atcgatctgc ggttttgtcg gttgtatgaa tggaagaacg atcactttca
      541 attcctctaa tagtcgttct gctttttctt tttttagagt gacgtctagt accttttcca
      601 taaattcatt tacagctgta ttaggatgac caagtacctc gtggatcttt tccgcagcta
      661 atgcttggac tgtttggact gtctttggat cattcactga actataggcg cttaacagct
      721 gctcgacttc tcgcttgata aaataatatt gatatggttt gattgttttt tccatgactt
      781 tgagtccttt cttctttcaa aatcggctac tttgaagaaa aaagtgatct ttctatcaaa
      841 gtgcctttag ataaagccct caaactcttt taaataagat acacatcgca tcttatcatc
      901 acccccttta tttttatgtt ggttatgtac tttttcatct caacaaagta aacactaaaa
      961 agaccaatta gtcaatgtct aaacaaaaaa cccgaggatt tttttcaaaa tactcgggtc
     1021 aaatacttag ttaactacct taaatcgatt gttctttacc gaaatatcgt tgccattttt
     1081 gtttcattga agctgtcatt ggttgagctg cttctttgac tgcacaatat ttatccacaa
     1141 aagtaacgat ataaccttct ttatatttag gaggggcaat cgttgctccc cacatatgtt
     1201 tcaaaataat atcacgctct agatctgaaa gctccgtgat tttttcagca tttttcacag
     1261 cgatccttgg gtgaacatac gcatgtgtac cttcatcgaa cttcgtcgta cgccaatcgt
     1321 agtaaaataa atcatgtaaa aggcctgctc gagcagtcgc tcttgcatca ccgccccatt
     1381 ttttcgctaa tttgtagcta tagtaagaca cactgattga atgctctaat cgtgtcgagt
     1441 ggacatgttg cgtgtaattt gctaatttct ttactgcatc agtttctaat agatcattta
     1501 tataagacat atattcttcg tcttcacgcc atttttctgt cataattatc gatctgccac
     1561 ctttttgaat tccatttatc tttgaaattg aacttagtat accactagtg ttcgtaatat
     1621 tctagtgagg ttttcgcaaa atgcagaaag cttaatagtt ccttaactat acggagaagt
     1681 gataaagcat gatgcccgct gcaactccta catttaaaga ctccgcattt ccttgaatcg
     1741 gtatatacac atttttatcc gttagcgcca gcacttctgg acgtacgcct tgaccttcat
     1801 tccccatcac gatcgcataa ttttctgttg tctggatatc attcagggac actgcttctt
     1861 cattcagttc tgttccatag gttataaatc cttgctcttt aaggataggc aatagttttg
     1921 ttagatcctc ttggatgatc ggtaaatgat agttactccc ctgcatgctt cttaatactt
     1981 tggtactgta gacatccgcc gttcccttac ctagtacaac acaagataga ccaaaagcat
     2041 cggctgtgcg gatcattgtc cctacattgc cgggatcttg tacgttgtcg agcaacaacc
     2101 aaccaccttc aaaattcggt atctctcttt tttcagcttc caccactgcc atgatccctt
     2161 gcggagttgg tagatctgaa acagttgcca tcacttcttc tgatactagt gtaacagaaa
     2221 gcgcctgatt ttcttcaagc caactagccc actcagtcag accgcgttgc gtaataaaaa
     2281 gttcgttgac cttcgcattt gaggcaacag cctcctcgat caggtgaaac ccttcaagca
     2341 gatattcccc tttttcttca cgatattttt tcttatgtaa tttttttaat tctttgattc
     2401 ttggattttt tgctgattgg atctctttca catttttcac ctcaactgat tataccatgg
     2461 attagatcat tgcacttgtt cagtagcaaa aaagtcggta tcattaattt aaaaataaaa
     2521 gaaagaacgg tgaataaaat gaacaaaatc aagatgaacg tgcaaggacg tgtacaaagc
     2581 gttggttttc gctatatgac aaaaatcgta gcggatcaat tagggatcac cggaacagtg
     2641 aaaaatgaag atgacggctc tgtcacgatc gaagctgcgg gcgacgatga ggcaatcaaa
     2701 aaattcgtgg aagaagtcaa acgatcacca agccccagcg gacgtgtcca atatgtagac
     2761 cttcaggaaa atccgatgat ggaggacaga aaaaagtttg ttgtaatagg ctgaccttct
     2821 agaaatgaat aggaaatgtc agaaaaatcg gactgtctgt atgtagatcg aaaaagtttg
     2881 cccctctctc catcctagat cgacaaaaaa acattcttat tagcgagttt agtaaccagt
     2941 gataggcata cgtaaaagcg ggaggacttc aaaaattttg gttcaataaa atggagtcta
     3001 taatatttta tggtagtgga aaatcgactt tgattttcca ctaccacttt ttcattgtca
     3061 aatcctgacg ctgcccagtc aacaagccaa ctctcgaaag gatcattttc cctctttgtt
     3121 ctaatggata cccatagctg ttttcaaata tacagtttta tctaaaaatt tagttttgct
     3181 aaacgatcaa aggcttcacc taagatttcc aatggctgag tcgctgctag tcgaatatag
     3241 ttgtccccga tcgtttcccc aaacgctttt ccagggacaa aaagtacgcc gcttttttct
     3301 aaaacctctt ccacaaacgt tactgaatcg agcccactct tactgatatt aataaaagca
     3361 tacatgcttc cagaaacaga agataaagat aagtaaggga tttctgccac tcttttctca
     3421 atataagcta atcgttcttt gaatacttca acaactggcg gtacaagctg ttcatagtgc
     3481 tttaaggcgt agattgcacc tctttgagaa gcagtcggtg cggaataagt gatgttttca
     3541 ttgatcaacc cagcaatttg attgatgtat gctggtgcga tcatgtaccc taagcgccag
     3601 ccagtcatcg caaacccctt cgatacacca ctgacagtga tcgtattatc gggcgcaaat
     3661 cgcgccatcg gtacgaactt ctctttaaag gcaaagtctt cataaatctc atcggaaatg
     3721 atatagagtt cattttcgat tgcgacttca gcgatttttt tcaacgtgct ttcagaaaaa
     3781 acagctcccg taggattatt cggcgaattg atgacgatca cctttgtacg atccgtaatc
     3841 gctgctttta aatcttccac atccaactgg aagccctttt cttcataggt aggaacaaaa
     3901 acaggcttgc ctccagataa aatgacttgt tcccgatatg gtgaaaaata aggttcatgg
     3961 atgatgacct catcctctgg atctagtaat gcctgtaaaa ctagatacat cccgtgcatt
     4021 gctccgactg tagctcgaac ttggttgcat tcaacgctca atccatattt cttttgataa
     4081 aaatctacga ccgttgacaa gaattctttg ctgccatcag gcgcagtata attagtagca
     4141 ccatttttta catctgtata agctgcttca ataatcgtcg gatcagtgat caagtcagga
     4201 tcaccaatcg ataaatcgat aatatcctct ttttcctttg ccaaaatagc aatattcatc
     4261 aacagatttt ctgctggttg ctgaaaccgg cgtgcaatct tacttttgtc catcttactt
     4321 cctccatctt tgttacaaca ctttgttcaa gaaatcctgt gttcgactat tttgcggatt
     4381 ttcaaaaatc tctttcggtg ttccctcttc ttgaatgatg ccgtcagcca taaaaatcac
     4441 acgatcggca acttctttag caaaacccat ttcatgagtg accacgacca tcgtcatccc
     4501 ttttttagct aaatcctgca tgactgccaa cacttcaccg accatttcag gatcaagtgc
     4561 agatgtaggt tcatcgaaaa gcatcacatc aggattcatt gctaatgctc gagcaattgc
     4621 tacccgttgt tgctgtcccc cagataaact ggtaggataa ctgtccactt tttcctttag
     4681 accaacttgg ttcaataatg atagagcatg ttcttttgct tttttagggt cttctttttt
     4741 gatttttaca ggtgtgatgg tcaaattttc gagtacattc atatggggaa acaaattaaa
     4801 actttgaaat accattccca ttttttgacg aatttgattg atatcgctgt caggggctgt
     4861 aatgttttgt cccttaaaaa agatttcacc agaagttggt tcttccagca gattcataca
     4921 acgtagaatt gtacttttcc cacttcctga agggccaatg atcaccacta cttctccttc
     4981 tttcacagaa agatcaattg attttaagac ttcattctcg ccaaaacttt ttgacagttt
     5041 ttttacatta agcattcaga cccattctcc tttcaactaa agctaatata cgggaaatac
     5101 tgaaggtcaa cacgaaataa atcaaagaga ccaacacata tggtaggaat ggtttgaagc
     5161 tagcaccttg taccacgccc gtttgaaaga tcaattccga taccccaatg accgaaacaa
     5221 ctgaggactc tttgatgatc gtgacaaact catttcctag agctggaaga atatttttga
     5281 ttgcttgtgg gaagatgatg aaacgcatgg cttctttctg gtccattcct aaagaacgtg
     5341 cagcttccat ctgtcctttg ttgaccgcat tgatcccggc acggacaatt tcggctacat
     5401 aagcagcact attcaacgag acagcaatac aacctgctac cagtttcgat agatccaatc
     5461 ccagtactcc tgttccgaag taaacgataa agatttgaac taagagaggt gttccccgta
     5521 cgtattcgat ataaataatg gctaatgcct ttaaaaattt attcttaccc aatttcatca
     5581 gtgcaagcaa actaccaaag accattccaa acaatacacc cacaaaagct aataaaatag
     5641 tgtattttgt tccaatcaaa taatacggac cgtatttttg aagaaaggac tgatcatctt
     5701 ggaacatcaa ttgattcgct tgtttttgat aatctttcag caagccgtcg tcattgatcg
     5761 ttttgattga cgcattgaca tgatttttca gttctggtgt attttttgac atcgcaatag
     5821 ctgtggtttt ttcgccttgc gcaaatttta ctggagtcaa agctactttc ttattctgtt
     5881 gggcatatgc ttctgcaact ggttgttcca gcacaacacc ttcaactttt tcattcagca
     5941 aattattgat cagatcagga actttttgca gggaggtcaa ctctgcacca gtcagttcat
     6001 ttttcactaa ctcctcttgt gtggtttgct tttgcgcccc aacggctaag ccagaaaagt
     6061 cggctgtcgt cttaaattta tttttgtcct ctttacgaac gagtactttt tgctgtacca
     6121 cgaaatatgg gtcagaaaag tcaacttctt gtaaacgttc ttcagtcacc gccataccag
     6181 atataactaa atcgatcttg ccagttttca acgcacctaa taatgcatca aaaccaagtt
     6241 cttctacttt tagtttcaca cccatatcct ttgcgatctt ttcggcaatg gatacatcaa
     6301 aaccaacgat tttatcctta ccatccacat tcgcatggaa ttcatagggc gcatagtctg
     6361 cagataggcc aacgactaat tctccacttt gttttatccg ctcgtaaatt tcatcttttt
     6421 ctgcaccttg tacttttact ggtaaaaaaa ccagtagaaa catcagcgcc actaataata
     6481 tgtttattcc ttttttcatc catttggcca cctttgaata ataatgtaat cagaaaagct
     6541 ataaaagaat aaatattcat aaataacttg ctaatatact agcataacta ttataataaa
     6601 aaaagattaa tttaaaaaaa taatggaaga agttttttat atgacaaaaa atttaattgt
     6661 tcgcggtgcc cctcaagagt atgaaataaa agaaaacgca tgggattcac tccctgaaca
     6721 cctttacaaa aggcatattg acaacgtttt gattctccat ggaaaaacat cttggaaagc
     6781 agtaaaagat gtttttccag atttatcaat aacaaaaatt tttgaatatt atggtggaga
     6841 atgtaccgat ccacttgctg acagttttgt ttctttatgc aaaaagaagg atttcaatgg
     6901 tattattgca gtcggcggcg ggaaagtagc agatctagga aaattgattg cctataagac
     6961 aaacttacca atcatcatct tacctacctt agctgcgacg tgcgcagctt atactccact
     7021 tagtgtggtc tataatgaag aaggagtgat gcttcgctat gatatgttcc ctaaagcaaa
     7081 tgatttagtg ttgatcgatc caaagatcat tttgcactcc cctcgcgaga tgatgattgc
     7141 cggtattggt gacaccttag caaaatggta tgaatctcac gcaatcatct ctcagttaac
     7201 tatcaagcct atcgaagtcc aagtagcgga atttgcagcg ttacgatgcc gcgaaatcct
     7261 tttagagaaa agtgcagagg caatggaagc gatggaccag caaaaaatca atcaagcttt
     7321 tatcgatgtc gtggaaacaa acattttatt ggctggtatg gttggtgggt ttggcgatga
     7381 ctacggccga acagctggag ctcattccat tcacgatgcg atgaccgtac tccctgatag
     7441 ccatcagcaa cttcatggaa acaaagttgc atacggtatc cttgtccagc tgatgatcga
     7501 aaataaatta gcagaaatcg aacacctact gccgttttat catcacttga acttaccaac
     7561 gagtttagct gatatgggtt tacatttaac agaaagtgac tatcaagccg tagctgaacg
     7621 tgcatgttta cctgatgaaa tgatccactt catgaaagaa acgatcacac cagcactggt
     7681 tgtccagaaa atgaaagagt tagaacaagt gacacaggga tagttagccc cttataccat
     7741 ggcagtcagc ttttttatgg atcggctcaa tggtaaaaaa aaagaagtgg aaaaaattga
     7801 cattccactt cttttttttg cgctaaaatt atgatttcaa ggaaatatcc gttgctcatc
     7861 ttattttaga gaacggaggt gctaagtatg ctttatactg aagtattttt agctggattc
     7921 ttctttttaa cattaagcgt cttttttgat cctccaatcg gttatttcta tgaaatttct
     7981 atgaagttga ttgaattatg agcgcttttt tagtatagtt aagcttgtgt aaaaattata
     8041 aaagaggaag tattttatga ataaatggaa aaattggtta ttgggctctg ggcttgtcac
     8101 gatcatgctt ttcttgtccg gttgtgtccg catggattca aatggtaacc ctgacacttc
     8161 aggaatcatt taccgtatat tggttcaccc aatgggacaa gcgattacat atttagtgga
     8221 aaactttaat tggtcctacg gctgggctgt tatcttgatg acagtcatcg ttcgtatcat
     8281 cattttgcca ttaggtatta gtcaatcgaa aaaaacaatg atccaatctg aaaagatgca
     8341 agcattgaaa ccacaagttg aagctacgca acaaaaattg aaagctgcga caactcgaga
     8401 agaacaaatg gctgcacaag ctgaaatgca acaagtttat cgtgaaaatg gcttaagtat
     8461 gactggtggt atcggttgtt taccgcttct gatccaaatg ccgatctttt ctgcgctata
     8521 tttcactgct cgctatacag aaggcatccg tgaatcaacc ttttacggga tcgacctagg
     8581 taaccctagc ttagttttag tagcgattgc cggtattgct tatttacttc aaggctatat
     8641 ctcaactatc ggtatccctg aagaacaaaa gaaaacgatg cgtacgatgt tgatcgtatc
     8701 acccgctatg atcgtcttca tgtcgatcag tgccccagct ggtgtcactc tttactgggt
     8761 agtcggtggg atctttagtt gtctacaaac attcattacg aatgtcatca tgaaaccaag
     8821 attaaaagcg caagttgcgg aagaattaaa acaaaatccg ccaaaacaag tggtgacgcc
     8881 tcgtaaagat gtcacacctg ctgaacctgc gaagcaaaca aaaaaacaag tacaagcacc
     8941 aaaaaacaat gcgaagaatg gtcggaatgc tggtaaacag caaaagcgta aatagttatt
     9001 tgtaactagc ttcttcgatc gacccagatc atttctgatt ttatgacgat aaaagccaac
     9061 gtactgtgaa atatagaaaa ctatatttcg cggtacgttg gcttttttat acacggcctc
     9121 tttatacatc cgtatttata tccagttgta tcaccagtca agaagttgtg cttgattatt
     9181 cttcttcatc gtctcccatg ccagcaatca cttggttcac tgaaacgata ctctcacgac
     9241 ccgaaccaat aaaatctggt tctgctccaa tcatttgcga attgatgaat tcgatgacca
     9301 tcggcaaatt catgccagca tatagttcga tcgtttcacc ttccatgatt agcttggaaa
     9361 cggtatttgc aggtgtccca cccaacagat cgcaaagcac tacgtaatct ttcaatggtg
     9421 ctgtaacgga gaggaatctt tctttatacg tgtccgcgcc atcttcaggc aataaaggga
     9481 tcgtatagat attttcttgt ggtcccatga tcatttctgt actgtttttt agttcttcac
     9541 aaaatttacc atgactaatc aagactagtt gtctactcat ctttccaatt ctcccttatt
     9601 tcgaaatcac acctaatgca gataatgcta cacatacgat caatacgatg aatattgctc
     9661 gagtaggtgt catatttttc ttacctaaca tccaataaac gccaccaacg attccagctg
     9721 gtaaaagttt aggtaagatc atatcgatat agttttgcat attcaacgtt acatccccaa
     9781 tcgttggtgc ccatgagaat ttaacattga tcatggttgc tactaacgct ccaaccatga
     9841 aaactcctag taaagtagcc gcatctgtca atgcagtcaa gcgtgattgc atcgtggtaa
     9901 ctagagaaat cccttctttg taggcaaatt ctagttgttt ccaacgaaag accatgacag
     9961 cgacctgagc aaggatccag ataaggatac ctactggatt accatctgtt gccatatttg
    10021 cggctaaagc tccaaatatg gtcgggatca atgccgcaaa tacagaatca ccaattgcag
    10081 cgaaggaacc catcaatcct gctttcatcc cagaaacagt ttcctttgaa gagactcctt
    10141 ctttttcttc gatagcaaga tcgatcccag taatgatcgt gttaaagaaa ttagacgtat
    10201 taaaaaattg cgtatgtgtt ttcatcattt cttttaattc tggtgtatca tcaccataga
    10261 tttttctaag ttgtggcaag atagtataca gataacctga accttgcatt ctttcatagt
    10321 tccaacctaa ttggaaagta aacaaacttc tacgattgat ctgcttaaaa tcttctttgg
    10381 tcaatttata attagatttc gtcatcttcg atttccccct catcagattg tgattgctga
    10441 cttactactg gatgttggtc attcttttga tcattcttat aactgatcgt tgccagtgct
    10501 agaccaatca atgccacagc aagcatcggt aatgaattga atgttcctgg gaaatctttg
    10561 accacgctag ccacacttgt tcctaacaat tggacattcg agaacactgt tgctaataac
    10621 gctgtgatcg taaatcctaa aatcagataa gaaatgtgtt tctttactgg taggtagcgt
    10681 agtaaaattg caaacccaac tgctggtaag actgcccctg caacagataa gccatctcct
    10741 agccatttta ggtcgccgtt taaaacagcc acaacatttt ggactaagcc accaccgaat
    10801 gctagggcca agaatacagg aaccattctg gaaagtgccc aaggtaatgc ccccatcaag
    10861 aagttccgtt caattgcttt gtaattcatt gtttccacat gttgatcgat ccgatgtgca
    10921 aaatacgtat tcgcaaaacg tgccaaaata tctaattgga tcatcaaact tgctacagga
    10981 accgcgatgg ccgcaatcgc ttgttctggg ttcatcccta gagaaatgga gaaagctgtt
    11041 gctaagatcg ttccagagtt ggcatcgatt tttgatgcac caccaaatgt ccctacccct
    11101 aaaacagtca actgcatact tccaccaatg attaaacctg cttttaaatc acccattact
    11161 aacccagcat ataatcctgc aaaaactggg gcgctcattg aagaataaat ctgtaattca
    11221 tctaaaattt gataccctgc atataatgtt aataataata tctgccacca ttgaatatcc
    11281 atgaatcatt cctcctattt gattaaaaga ctcataaagt cttctgcttt gtcatttggc
    11341 accatttgag cgatcaaatg aacgccaagc tgatctaatt tcttgaagac ctctacatcc
    11401 gcatctacga cattgattga ttttgtgatg gaacgtgttt catctgtttg tgacatattg
    11461 ccgacattta attctttgat cggtacacct ttttctacta gcgctaagat acgatctggt
    11521 tttttcgcta cgatcagcac tcgttgagaa tcatatttac ctgctaaaat atttgcggct
    11581 gctttttcaa taggtaaaat acttaatttg actccagctg gcgttgccaa ctttaaccca
    11641 cttttttcga tcgcatttgt tgctacctca tcgtctacga ccatgatccg accaatattc
    11701 aactttgtcg tccaaagatt tgccacttgt ccatgtatca aacgtccatc aattcttact
    11761 ccaataattg ccatcatcca ttctcctttt ctaacttttt tctattggtt ctttgacaaa
    11821 atctataact tcactgaatc taccttctgt ttcaaagata acgatttcat tttgtccttt
    11881 tctaaataaa ccctcgggaa caaacagtga aagaattggt cctacttccc aaaaacgacc
    11941 aatattcgtg ccattcaccc aaacgatccc tttcccaaac tcactaaggt ccaaataagt
    12001 atcaccgatt tctgacagtt ccgcttcaaa gcggtaaaat gctggttgac ctgcttccca
    12061 tttttttgaa aaatcgatgt gttctgtagt ctctaaaggt aaacaatact gtgtccattc
    12121 tgtgataaaa tgaagatcgc tcatcactcc tgtacgtatt ccttttcttt gcgtatcagc
    12181 tagcagcttg tgtccatagt tgacccgtcc catattttca aataatagat caatttgatg
    12241 gtcttctttc tcaagtgtca atggaatggt ctcaccgatc tctgtttggt attgaatcgc
    12301 ttgcttttct tcatcgagaa aaacatggac ccgatcacgt ccgtcgatga tccgtaattt
    12361 ttcattgacc gcatcttttt tgatcgttgt tcgatacaat aggtacccag tattctgacc
    12421 caattcttcc attgtttgag gataggtcga gtggatcggc ttgctgatgg tatccagtgt
    12481 tgcgaaaaag ctgacttttt ctttcaagtt gattcctttt ttgacgattg tttcttttat
    12541 ccatggttcc atttgctgca tttctggaaa attttctgcc atcattcgtt tcagagcaaa
    12601 atatttttcc gttggatttc cctgctcatc caatggtgca tcgtaatcat aggaagtgac
    12661 ttgcggcaaa tcaatcgcgc ctctggctga acagccattc ataaacccaa aattggttcc
    12721 gccatggaac atatagagat tgatactgcc gatctgtaat gcttctttga ctgcatccgc
    12781 taattcttcc ggatctcttt taatgatcgg ctctttccaa cgattaaacc agccatccca
    12841 aaattccata cacatcaacg gccatttttt accatgtgct tcaaaaaact gggccatatc
    12901 tgcaaaattt tcttttgctt ttgagccaaa attccctgtc gtaaaaacat catcgtcaat
    12961 caaaatgcct gctcttaatg tggcttgcca aggtccatca gaagtgaata gcggtacatc
    13021 gattccacct tcctccaagt atttttttac ttggcgcagg tatgctttct cttcaccata
    13081 cgaaccgtac tcattttcta cctgcaccat taagacgttg ccaccatgag tgactagatg
    13141 aggaacgatt ttaggtagta gcgtttggta ataccgtttg acatacttca tgaagcgagg
    13201 atccgctgaa cgaatacggc actcctttgt caatagccaa gcaggcaagc caccaaattc
    13261 ccattctgca caaatataag gggctggacg tacgattgcg tataatccaa gggattgcgc
    13321 taactctaga aaatgggaaa gatccaatat tttcgaaaaa tcataggttc cttcttcttt
    13381 ttcatggaga ttccaaggca cataggtttc cacagtatta aatccaagcg ctttcaaatt
    13441 gtgcaatgac cgctcccaat tcgtcggatg cactcggaaa taatggatgg caccagataa
    13501 aattttgaaa ggttgaccgt ctaacaaaaa ctcttctttt atttcaaatc tagtcaagca
    13561 aatttcctcc tcgtttttag aaaccgcttt ctaattttat aatcaacgaa tctttctgac
    13621 gttgatttcc cccctaaaat aatcgacttt cacaggatcg atccatcctg ttttttcttg
    13681 ttgtgcattc gccatcccac aggccatcgc aaacgcaagt gtttcttcaa tcgtatagct
    13741 ctttgataga gcatgtgcta agcctgcaat agtcgaatct cctgacccca caggattcac
    13801 caccgcgatt ttaggaatcg taacctgata gaagtgtctc cctactttag cgattgctcc
    13861 ttttgcgcct agcgaaagaa cgatccaatt gattccttca aaaagcggat gatccaataa
    13921 tgattggatt tcatctaacg aagtagccga agaaattgtt tggtggacca actctcctaa
    13981 ttcttccaaa ttaggtttga tcaaaaatgg tttttccttg ccttccaaga cttcaagcaa
    14041 ggtttgacca gaagtatcta acaatactcg tgttcctttt ttattcgtta gggcaagtaa
    14101 ctctgcataa taacttttag aaaatccttg aggcagacta cccgaaatcg taaagatatc
    14161 agttgtttcc attagtcgtg caaaatgctc ggtaaattta tgttgctctt cttccgtcac
    14221 aacaggaccg ctttccaata gttctgtttg attcactcca tgtaaaatag caatcgaatc
    14281 tctcgtttcc cctttgatag gtaaaaattg atgcgttatc cctgattgat cgagttgttc
    14341 tttgatatat gctccatgct gcccgccgac taatccagta gctaaaacat catctgctaa
    14401 taaatgaagg acacgagcaa cattcaagcc ttttcctcca gccgttttgt tgaccgtttt
    14461 gacccgattg acttggtcga tccgtaattc atccaacgtg taagcgatgt caattgaagg
    14521 attcatggta actgtcgtga tcattttgct gtcaccgaat cttcttttac tttgtcaaac
    14581 caaggggtgg cgttttcatt tatcacttta ttcaacgatt cgatattttg tcgcccttgt
    14641 gttctcaacc actcaatcgc accttctcta ccattttcaa catatgcttt gactccatct
    14701 ttccaagtcg cacgtccgca taacacaccg ttgaatgttg aaccagattc atgagcaaag
    14761 atcaatgttt gttggaacaa tgcagtcgaa acccctgcac tcaagaagat aaatggtaac
    14821 ggtgttgcat cactttgttc cttgaagaat gccgctgctt cttttttact atacgcaatt
    14881 tcaccatcag aataaccttc tacatagttc atattgactg gcacttctac tttcaataca
    14941 tccactttat atttaggatc agaaaattct ttcatcatct cgatcacttt atgcggtttg
    15001 atcttcgcat attctaatga agtgctgtca ttggttttgg catcatacga aaccaattct
    15061 agataaaacg gacgcttttc acctgcacat tcactgccta aacgttcgat aaatacatgt
    15121 ttcaaatgat tgatctctgg gtcttcatct acatcataat aaagcaaaaa cttgatcgca
    15181 tcggctgttt gttcctttaa tctaagcgta gaccaatccg ctaataaatc aggcagacgt
    15241 cctggagttg tcgcatcata acccgttttt tcataggcta aaagtagtcc tgcttcctga
    15301 tgtctggctt tagcagctgg caatccatac tctggatcta gtaaaatagc agaagcataa
    15361 ggcgttaatt ctgctgatac taattctttg aattcagtga tctgttgcgc cgttggttct
    15421 tttcctaacg ctttgatcat ctttttcaaa gcaccgcgtt gatcaattgc caatgcactg
    15481 atgattcctt cttttgttga taaactcttc atagctgcaa ttttttcttc attcatcctt
    15541 cgtttcccct ttgttcacat attcatggat aatgacacct ttgaccactc gattgactgt
    15601 acctgtaggc gatggtgtat ctggtttatt cgctactttt atcgacgtat cgagcgcaat
    15661 gatttgggct gtcatgatca taggtaaggc aagatacgca tcaggtaggc tgatcgaagc
    15721 ttctaacaaa agacttgtac ctgtgaaatc gatgtttcct ggttgggcga tcgcgatgac
    15781 actcgtggta atttggtcat cttttatttc ttctagaata tctaagtcat aatttcttgt
    15841 atacggttgg ttattaacaa aaccaataac aagtgtttcg ctatttaaaa acgattttgg
    15901 tccatggcgg aagcccatag aagaatcaaa gatcgttgcc actttaccgg ctgtcaattc
    15961 caatattttc aattgtgctt ctctcgttgc accagccaaa cttcctgaac caagataggc
    16021 gatacgttca aatgacttag gcaataattt ttggatttct tgatctcgtg aaattagatc
    16081 ttctccagtt ctgatcaatt gttgaagata actttctttt ttctcaacgg cagtttggtc
    16141 gaatacccat aacgcactca acaacatgca cgtaaaactt cctgtcatgg caaatcctgc
    16201 atcatttgat ttttctggca tcagtaaaag ataatttcgt tcatctgtcg ctgcattctt
    16261 tgctaactga ccttctttag cacaagtaat cgtcaaatga aacaatgtct tgatttgttc
    16321 attggcaatc ttgactgttg ccacactttc tggactattt ccactacgtg caaatgacac
    16381 cagtaatgtc ggttcatccg gaaatagaaa ttcttttggt gaagacacga tatctgtcgt
    16441 accaaagcta tgaaaaataa agtgatcgtt atcaccgtat tcatttaaat aaggtactgc
    16501 tgtatccccg acatattgtg atgtgcctgc accagtaaaa atcactcgaa ctcttttgcc
    16561 atttgctgct ttttttatct ggtcaaaaaa caatgctaat ttttcttgat tctgtgctaa
    16621 tatctcagct gtttctttcc ataattgcgg ttgctgtttg atttctcgcg tagttatttc
    16681 cgcacccaac tcttttaatt tatccttcga tagttcaaac atgttgtttt ccctctcaat
    16741 cattttcgga cgtggcggat cttataatga aactggtctg ctctcgctac actatccgta
    16801 tattcaataa tttcattttt cacattatag gtcgttcggc ttagatataa taccggggca
    16861 ccatcagcga tacgaagcgg atcagcatct ttcttttgaa cgatacttgc ataaaattct
    16921 tcatctgcta attggacttg ctgttcataa tcctgagaaa acacatcata caatggctta
    16981 ctttcaagta atggcagatc aagaccaata aatagttttg caggtaaata agaacgttcc
    17041 accatcaatg gttcgtcatc cgctaaacga agtcttttca atttgaaaac tgtttcgcct
    17101 aaattgatgt ttagattctt ggcaaccttt ttgtttgctt ccatttgctt gaattccaag
    17161 atgactgtat taggcacccg tcccaattcc ctcatctctt ctgtaaaact atacgctccc
    17221 gccagatcag acgacttatc tgatagatca gacacatatg ttccttttcc gtgtcggcga
    17281 taaatatacc cttgcgtctc taattcttgc aaagcaaggc gaaccgttgt ccgactcact
    17341 ccataatgct gacaaagttc tctttcagat aacaatttgt catgaggtgt catctgtgtt
    17401 tcgatacgtt ctttcaatac gtcaactagt tgataatata atgattttcc tttacttgag
    17461 ctctccataa aaatacctct tctttactgg ttataaccac aacacaagaa tacccacata
    17521 ttcctcattt gtcaaagggt ttttggcgta aaaaagctat tataacaagg tttcaaggta
    17581 atttagaact ggtatcaaaa gatacctcaa aaataccagt tgacaaataa aaaacaaaaa
    17641 aaagctgaat cttggcaaag attcagctaa atggtctaga gaagtaaaga aaaaatattc
    17701 tttatacatc tgtggctatt tctactatcg acaagcaaat gggcctaata gactactatg
    17761 taaataaaaa tggctttctc taaataaagt aggatttttt attttttaga taacttttct
    17821 ctcatgccgg tctgatagtc gaaattttgt tgtacatttt taaaaataac aaaaattttt
    17881 tatgataatt ctgtcttttt ctagtttcct tatggcgtaa gtttaacgaa taagaattta
    17941 gtatctatac ttttatatta caaaaaatat tcgtaaaatt cgggctctat acttttcgat
    18001 gtttgtgaac tttatcaaca tcttttttgt ataaaaaaat atagaaaaga caccctgaaa
    18061 tcctttagaa ttaatttgcc caacaaattc ataggaggat tcaagatgtc tcatactctg
    18121 cttatcaaag ataccctaaa tattctagac ctaaatatca atatccattt cgaggaaaat
    18181 tgtttaacta aagaaaaata caaaggacaa atttgcttga tttacaaagg gactcttcag
    18241 tacacaccag aagaatatcc acatcttcca atatattaaa agaaccttct tgaatcattg
    18301 agtgaaagaa aagagattcg tcactatttg aggactgttt aactagagac attagcgatc
    18361 tgcctgaaac ctatacaacc actttacgaa cgtttaaaaa ttttctgcca cagattcaaa
    18421 atgcgcttaa ctgcagctat tcaaacagac cattggaatg tttaaacaac cacatcaaag
    18481 tattaaaacg caatacgtat ggctttcgca gcttttacaa tttcaaacta cggatcatga
    18541 ttcgtcatgg caaaacattt ttaaccaaat aaacagaaga atgtgggata aatctaaaaa
    18601 tcagttttgc tacagactct cgagtaaacg gcgggagcag aagcaactcc ttcggaaata
    18661 agccgaaatt cacaaaaatt tgaaaagcaa ttttcgtgaa tttcttctta tttctcggag
    18721 ttaaacactt ctgtcccagc ctcttctgtc caaattattc taagatttct ctttaccaac
    18781 atcatttgac aaagagcttc ttttttgaat actatattcg ttctgttttt catcttcaaa
    18841 tacgaactca tccgcagaaa tatttgtcac aactccatga atcttctttt cattaccacc
    18901 tatataccac aggattccta cacagaaaca acaaaaaaat agcataaaat aggttttctt
    18961 tattttatat ccctcctttt agattaaaag ctcacagaaa acgctttcta aaaagacaat
    19021 agaataatca taatttttca ttttgtatta tttatacaaa taatacgcat gttactgaaa
    19081 aatgatatgg ttccctactt tttgagataa gttaaataaa atctgtcatc gataaaacag
    19141 ctagtacagt aatgataaat agtaagaact taaaatattt tggattttta tttttgaaat
    19201 aatcgaagaa aagtaaaagt gataacgaaa tagcaaacaa gattatatct ataagattat
    19261 tcattgagaa atcgccccat atggaactct attttgacct gacacaccga gacataaagc
    19321 aatcatatcc tctgcattgt tttatactat tagaactata gctacaccta ttggatgcta
    19381 ctggctctaa gattaatgct aatacagtaa catcaatacc taaactagca gaaactctat
    19441 ttgcatcttc aatttcagat gcctggactg tcgtgactag cgccgtagta gaaaaattta
    19501 ctggtactaa caaagatgca gacacgactt ttatttcact tatcctttat cccataacct
    19561 aaacttcaat cattacttgt gagctgatca atgttcttcc aagtctgaaa gaacattgat
    19621 cagcttggca aacaaataat gttttcaaat acttgatcga tgaaaaaaag ctattggtaa
    19681 taacagtaat tgcattttcc attttcgtgt cagatacttc gcttacagct ggtaaacgat
    19741 caatcccatt gtcaaatttt ggattttttt ctgatgatgt cttgctttag ttcataaaat
    19801 aatccagcaa taaattcctc gcaaggatag ccaacttcat tttcctaatc ggaattttta
    19861 aacttatcgg tatagataca gatgcaatga gaacaaacat ttatttcgag tcaccatcta
    19921 aaatattttc ctccatgtac ccgttcatta ttatttagtt atcaccaaag atatctctgg
    19981 tataaacttt ttcttcaaca tcctttaaaa tatcttcaaa ccgattagat acgatcacat
    20041 cagaaatatt tttaaattca ttaatatctt tcaatacttg tgaatgataa aattcatctt
    20101 catccaatgt aggctcgtaa acaaccactt caattccttt ggctttaatc cgtttcataa
    20161 ttccttggat cgacgaatat cgaaaattat ctgaaccggc cttcatcgtt aaacgataga
    20221 ttccaacaac atttggtttt ttcgccaaaa tctgtccagc aataaaatct ttccttgttg
    20281 tatttgcatc aacaattgca ctgatgatat tgcttggtac tttttcatag ttggctctta
    20341 attgttttgt gtctttgggt aaacagtatc caccatagcc aaaagaagga ttattataat
    20401 gcgaaccgat ccgtggatcc aaaccgacac cttcaataat ttgcttacta tcaagcccac
    20461 gaaattctgc atacgtatct aattcattga aatacgccac tcgcaatgcc aaatatgtat
    20521 tcgagaataa tttaatagct tctgcttcag ttgagtgagt caaaagaact gatgcatctt
    20581 tgttaaatgc gtttctttga aacatagttg caatctcgcg accacgagca gaacattctc
    20641 caactataat tcttgatgga tataagttgt cgtacaaagc ttttccttca cgcaaaaatt
    20701 caggtgaaaa aatgatgttt tctgtaccaa atttcgcttt aatttcattt gcatagccaa
    20761 ctggaactgt cgacttaata atgaatgttg aatctggacg aattgctaaa gccttctcaa
    20821 ttacatcttc tactgttgat gtattaaaat agtttttctt ttcgtcataa tctgttggag
    20881 ttgcaataat caagtaatca ccgaagttta ctgcatcagt aaaatttgac gtaaattcga
    20941 catttaagtc atcccgtttt aaaaattcat gaacttcttt atcttctatt ggtgagatgc
    21001 cattttgtaa catcgtgatt ttttcttcca cgatatcata agctttgacc tgctcttttt
    21061 gtgctaataa tagtgaattt gctagaccaa catagcctaa tccgaaaact gaaattttca
    21121 tattcttcca tacgctccaa tcaaatttca ttttatagta ttttagctgt tatccttttg
    21181 aacatattcc ttattcaatc aatattattt aatagaaaaa atttttttgc ttcaaaatca
    21241 tcgaggttcg atatttaata aattcatttt tatttttctc ataatgctcc tctatagttg
    21301 aaatcacttt acatgaacta cccgctacaa cactattatt tgggatatct ttatttacta
    21361 aagtgttcgc tctaataatt acattatcgc caattgaaac tcctgggaaa acaatagagt
    21421 aaataccaat aaaaatatta tttcccaatt tgatcctacc tatttttgaa gttgactcgc
    21481 tcacagaact catcttcctt aagacccaga ctccaccatc gtgtgttata aatttaacac
    21541 caaatgaaca tctgaaatta tcccctattt caattaaata tggctcgctc ccaaattcag
    21601 gaacctctac taaactatgt ttttttccga atatcaaacc ttcattaata cattctcgca
    21661 gattttttcc aaatagtttt ctctttattc ttcgaaagat tctattctta cttcgtatac
    21721 cctcaccttt tagccatttt tattctgaaa aattttttta gatacgttat aattaattgt
    21781 ttatacgtaa aaacgaaaat agcactaaaa ataatcgtta agaaaagatt aaaatagaag
    21841 cctctatgaa tgcatacaaa agcgattgcg gaatagagaa ctaaaagtag cgatattcgc
    21901 ttccaatcaa atgcataata agcaattttc cttccaaaat aatatctaag tccaaataat
    21961 actaaagtac cgagcaaagt agcaaatgag acaccaatta ctccaaaaga atagcctaat
    22021 aaataggtgc caacaacact caatagacct gacactactg aaatcattaa taactgattt
    22081 gttttattgt atactgcaaa tatatttccg atatttgttg tcatcccact gaaacatgcc
    22141 ataataacta atattggaac tagaactaat gattttttat aatcagggtt ggttataaaa
    22201 gagtatgcac agcaaatgat aggaatagaa agagtcgcta acctaatgta cattttaaaa
    22261 atataggtat ttttctcaac gaatctttcg atgaaatcat cattctcaga cgtgataacc
    22321 gcatcctcta tcatagacat actaacaata cttgtaagag ttaaaattat agatgaaaat
    22381 ttcatcgcaa aagaaaaaat accattttct gttactccga tgtacgttcc aatataaaat
    22441 cttgaaaaac caactattag ccatccaaaa gtgagattca aagtgagtgg gatagagtat
    22501 ttcagcatgg actttaaaaa taaaaaatca aaagaactcg ttgcgaaata ttgaaagatc
    22561 tgccccctga aaatcaaaaa aatcaaattt ataacattag aaattatgat agagagtaag
    22621 agaccaagta tccccatacc cattgtaaca acaaaaatag taaggagtaa caggttgata
    22681 cccgcagcga ttataccact catcacaaaa atctttgatt cacctagtgc tcttacaata
    22741 tattgaaaaa cacttaggat aggagtgaaa attaattgaa aaacaaacaa ttgataatac
    22801 tctaaattcg ggaaaatcat tctatatatt attggtaaaa aaatggctaa tatcactgta
    22861 tttgctataa caaaacaaat actgttcgtc actacttttt tctgaatatt tttttctttg
    22921 cctaatccca tgcgtaaaat tgcttcccat attgctccaa aaataactgg agaaagaaat
    22981 tgagcaattg tattttgata atcaaagctt cctaaatcgg caacagaaat atatactgca
    23041 tagataggga ttataatgac agatatcatt tttgatgata atgttcctat tgcgtaaata
    23101 aaagcttttt tagctattga atgtgattta ttactgctac tatccaaccg tatgacctcc
    23161 ctcaactcac atctatagat gactttctgg tttaattaga actacctaaa ttcctctgta
    23221 tcgtgtgagt cctcgtagta aaaatttttt tgaatatgtg aatagctaag atcttttcaa
    23281 ataaagatat ccatgatcaa ctatatattt cttcaatctc atcaatcaat attggcagtc
    23341 agaatccagt tcacacatct tgatacacaa ttttgtttta tagaaattct tttagttata
    23401 gaaaatatct attcggcgag aaagttcgtc acgtttgaaa gtagaatttc ctaaaatacc
    23461 taacaaagct aaaaaaatcg tatgaattac ccatcttcaa tattcctttc aaaattaact
    23521 caaataatac actgtatacc attcaacgaa ttttttaatg ccctcatcca aggttatatt
    23581 cggtttaaag ttgatttttt cctctaaatc ttcaatatcg gcataagttc taacgacatc
    23641 acccggctgc atgtccaaaa aaatcttgtt cgctttaaca cctaaatact tttcaattgt
    23701 ttcaacaaac tccaacaatg caaccggctt attatttcca atattgtata tcttatatgg
    23761 tgcccaactt tcactactca aatcatcgat gtctgtccag tcggagttgg gttcaggtac
    23821 tttattgatt aatctagtga ttccctctac gatatcatcg atgtaagtga aatctctttc
    23881 catctttcca tggttaaaaa tcttaatttc ttttccagat aaaatattct tggtaaaaga
    23941 gaaataggcc atatctggtc gcccaaatgg accatagaca gtgaaaaatc tcagcccagt
    24001 tgttggtatt ttataaaggt ggctataagt atgagccatt aattcattcg attttttggt
    24061 agccgcataa aggctaactg gatgatccac cgaatcttct gttgaaaacg gtactttcgt
    24121 gttcccacca tatactgaac tagatgatgc atataataga tgctttacag ggaagtttcg
    24181 gcaggcttca agaatattaa gaaaaccgat aatattagaa tcaatataag cataagggtt
    24241 ttcaatagaa tatctaacac ctgcttgagc agctaaatga attactatgt caaaaccttc
    24301 actttcaaat agagaatcta atttttcttt ctctaataga tccattctga taaatttaaa
    24361 attattataa tcgtacagta tcgttaatcg atcttctttt aattggacat cataataatc
    24421 attgagatta tcaatcgcta caatttgatt ttcagtttcc ttgagtaatt ttctagacaa
    24481 atgaaaacca ataaatcctg ctccacctgt tattaatatt ttcattttta ttcatccacc
    24541 tttttctgaa aggaaccaat agggttaaac ccaaaattgc tttcttcttt atactcgtat
    24601 tacatttatt atttaggcat accccataat ttaagatata acgaagttta tgatactatg
    24661 cgtcttctcc attcactcaa aaaatataac ttaatttttt atgactttaa aaaggaaatc
    24721 ttctatctcc aaatatttac taggatttga aagaatagtt tagaaatcat ttagggctaa
    24781 taatgactta tgattcttaa tttagcgctt ttatatacat tattgcctaa ggtagtcact
    24841 tccttcattg catgtccgga cttccacaac acgtaaggaa atgcgagctg atctcgccca
    24901 ctttctgagt tcaaatactc tctccaccac aaatctagaa gattctcagc gattgaatta
    24961 tttaaatcaa ctaaaataac cgtggcttca gccaatccaa aattatcagg aaatccttct
    25021 tctctgtact tactaatttg ctctataata ctttccttat tacctttgcc aactgcaatt
    25081 aatgcatctg cctcagaata taaagatttt ctttcactat gtttatgcat acttaaccca
    25141 agtttggaag aactgttcag taatccggta atatcagaag ttattgttac attaccatca
    25201 acatacaaag taaaatcgta gtcagtaaat agctcattag gatgaaattt aatatatcta
    25261 ttgatcaaaa tattattttt taattccgat atatatttag gtatctctct aatattccaa
    25321 tgctcacttg taatcacatt atctgtatac aaatagtaat ctaccaatgg atgagaaaaa
    25381 tccggttctt taatagaatc ataattacca gtgatacaac tatacacagc aatcctttta
    25441 ggtgttcctt gattagttaa ctcttttttt cttagttcat cactgcgatt ctctctgttt
    25501 gaatagtctt taataggccc cttaccggtc atcgatttaa gggtatattt tgctggcaac
    25561 agattatctc gttttttcat ttggttaagt tgattaattt tatttcgtat tttcatgcct
    25621 aaaatagaat tatttttttg atttaattca tgtatttcaa gatttctttt ttccaattca
    25681 ttgatagcta aactatataa ttcttgtctt cccataaatc cctcatctct atttttaagt
    25741 gctatttatt cttactcaaa aaaatagtaa acagccttaa aaataatatt ttctctaaat
    25801 aatggtagga ttccatttac aaaagcagtt cctcttatat tgatgaatat caaacacaca
    25861 atgataaaaa agaaatacgc aagcaagtag atataattct ttacttttgt tctcttataa
    25921 ttactcatta atacactggc ataaataata taatttaata caaatatatt ttgaataatt
    25981 ctaataaaat tattacttat aagtaagaaa actatactag tagaagctaa catattgata
    26041 gaaaatatat atgagcttaa gctgataact tttttttcgt aaatattcat ttttgataat
    26101 ttatgaacta aaaaaagatt tgctgaaaaa aagagagcaa acatcactac gtgagaaatc
    26161 gatgtactgt ttctatcaaa atatgcatca tacttcgtat ttataaatat tgaactgata
    26221 taactttgtc caatagagaa taggagcaag ctaaggattg taacatatcc agtaatcttt
    26281 ttattaattt ttacaataaa aaaagggaga taaaaatatg caagattatg gaacagtcca
    26341 gccactaaga taaaaaaaat atacttaaat atagctttgc tgcctcgcaa tttagttaga
    26401 tgataaaaag ctagtaatat gaatatcaat gcgctaaaca tacgtacttg tattgcttgt
    26461 gaagtaaaac caaaaataaa aaacaagaac aaaactaaaa aaacattagt tgtgaataat
    26521 ctgatgacat acaataaagc tgagagtaag acagtagaaa taatcaataa aaaaatctga
    26581 tactgactgg aaataaaggt acatacgtac ataacagctc tgaatcccgg ttcaatacta
    26641 tctgaactaa agtccatacc aaattgtgct atcccattat acaagacaga atatgcataa
    26701 taatcagcgt tttgtgtgtt aaatgccatg atgatccaca ttatcaaaag tagcacccca
    26761 gacaaaatct tgttcgatgt actccatttt ttttgtgaaa cactcttttc ttgattaatc
    26821 tccaatgacg cctctgtatc catctcgaac cccccttata gccgctctaa atctactgag
    26881 cttatcagtc tcaaaagcta ttgcaataaa aaatttcaat aatcttttat tcataaggcg
    26941 ggaaaattcc ttatcacttt tatacattct tttcaccaat gttgaatttc ttgcaataaa
    27001 atactttcgt gttgaattat gattgtctat tttaattttt tttgatccta tttttaaatt
    27061 ttctccatct ccaacgtgat gataaaaata gacttgattt gttacataaa tgttatagcc
    27121 attatttgca acccttttac aaaattcaac atcaatctga tcaataaaaa attcatcctt
    27181 catatttcca acatcgtcaa ttaattcact tttgaaaaac attccagagg aatttgcaaa
    27241 tgctattttc atggaaccac tagttgaagc aaagtgtttt tttacgtatc tccctctctc
    27301 atttttgcag gtaaaagaga cagattcatc attgctattc tcaaagtaat tgggaacaat
    27361 aatcccaatg tccttatctt tcgcttcaat attggtaaac tcttctaata attttaaaga
    27421 aagattcttt tgtatgatgg tatcttgatc tagtaaaagg atataatcac atttctcttt
    27481 tttggcaatt tcaataccta tgttttgagc tgtcgcaagc ccaatgttct cattcatttt
    27541 ttttaaaatt aagttttcca tcatttcaaa ttgaaaagag ttaatattat ctgagccgtt
    27601 atccacgata ataagtttgt tctgtttctc ttgtattaac gtatccacta ataactttat
    27661 gttattatct ggattgtagg taacaataat tatcccaatt ttatttttca tcgttcatca
    27721 ccttgtacac ttcattccat ttcattttca atacttgctc agagaatata gtggcgtaaa
    27781 tttttctaac attttcattt atgtttttat tacactgata aaatttcaac atctcatttt
    27841 catcaacggt actattataa ttgattccga cattatatct tttaactatt tctttcgtat
    27901 ctcctgataa atttgaaatt ataggtaatc caaacctaaa atactcaatc gatttcagac
    27961 ttaaaccaat tatggtattt gacttaaata aatttagtcc aaaatgacat ttatcgagta
    28021 taactttttt ttctgcattg tcatatataa caccgcagtc aacaaattca atatgatttt
    28081 tttcacaaat atcagctaat ttagttttgc tttcaccttt tccaataaag taaagattta
    28141 ttttgtttcc aaattttctt ttgcatgttt tcaataattc attaatcgct tctaaatcta
    28201 cgatattatt aatcgtacct aaataagcaa ggttcaacgt agactctaag cttttattga
    28261 ctattttctc tccataatca ttttggtcat ctacattgaa agaacatgga taaatggtca
    28321 tattttttga ttctccggaa atttttatga attttttgaa ataatcgcat tctgttataa
    28381 ctagactaga attactgaga tattgatctc gtagcttttt ccataaatca gtaaaaaatt
    28441 tatatttgtt ccctattccc ggcattgact ctggccataa atcatacaca tcaaaaataa
    28501 ctcgattgca tctactaaac ttagcaataa aaaaaactaa ggtattaggt ggtattctac
    28561 aataaataat ttcaggcttt tcttttcgaa taaataataa tgtttttatt gaaaaccata
    28621 tatgagataa aattcgcatt acggatatat tttttttata tccgatcgtt tttatcacat
    28681 gacgattttt aatcatatgc ctttctttac tggatagaaa ttgttttctt atatgtgagt
    28741 aatcagatac aacattaaaa tattcgatac tgttttccgt cagaatttcc tctaatatat
    28801 tcgttcgact gatataatca aaaggatgaa taagcagcca ctttttttta ttctcactca
    28861 tctatcttcg caccctcaaa tttctcagta gtcccacttg ctactgatgt tattccatca
    28921 cggacaataa ctttctttag cgttaaaaaa aatattttta tgtctttcat cattgaaatg
    28981 ttctccacat attcaatatc tttttcaaat ttttctttcc aactaattgc attacgacca
    29041 ctgacttgag ctaatccggt taaacctggg cgcacaaaat gtctttttcg ttgttcatta
    29101 ctgtatagtg aaagatactc aactaacaga ggacgcggtc caataatact catatctcct
    29161 tttaaaatat tccataattc tggtagttca tcaagactag tcgaacgcaa tattttacca
    29221 aattgagtca atctgatatc gtctgataat aaattacctt cttcatctct ttgatctgtc
    29281 attgttcgaa atttatacat cagaaaaatc ttttcatgtt ttccaggtcg ttgttgttta
    29341 aagatcactg gcgatccaag ctttattcga actaggattg caacaaacgt catcagtggc
    29401 cataacatta ttaaacctaa aattgaaaaa agaatatcta tcaaacgttt aaagaacttt
    29461 tcgtagatac ctctattaga cattttgcat cactcgctta attgtattag ttactcgata
    29521 caaatcatca tcggtcattt tagaatctga aggtaaacag ataccttttt caaacaatgt
    29581 ctgagcaaca tctgtaccaa tatactcata cttatcgaaa actggctgta aatgcattgg
    29641 tttccatatc gggcgggctt ctatattatt tttatctaac tcatcaataa gatgattcgt
    29701 atttattccc tttactgtta tgacacttaa ccaataattt ggttcattcc aattattttc
    29761 tggcatgaat tgtatatttg acaatttaga caattctttt ttataaaaac tatgaatata
    29821 tcgttttttc tcaattcttt catttaaaac tttcaattgt cctcgaccga tacctgcaac
    29881 gatattgctc attcgataat tatagccaat ttcattgtgt tgataatggc gtgccttctc
    29941 acgagattgc gtagcccaaa acctcacttt ttccaccttt tctttgtcat tagacacaag
    30001 cattccgcca cctgaagtcg tgattatctt atttccatta aaagaataaa ttccatagtc
    30061 gccgaatgta ccagtatatt ttcctttata tgttgttcct aatgattctg cagcatcttc
    30121 aattaaaaca acattatgtt ctttgcatat tttagtaatt tcatctagtt cagctgataa
    30181 accgtacaaa tgcactacta atacagcttt tgcgttagga tatttttcta gcgctgttcg
    30241 caaatgttca gggttcatat tccaagtttc gtaatcacta tcaacaaata ctggaatagc
    30301 tccttgatag atgattggat tggcagtagc tgagaacgtc aaagactgac aaatcactat
    30361 atcatcttta ccgaccccag ccgcttttaa agctagatgt atagctgctg ttccagaaga
    30421 tagtgcagct gcatgactag caccgacata ttctgctaat tcctcttcaa aaccattgac
    30481 attcataccc aaaggagcca cccaatttgt atcaaatgct tcttttacat actcttgttc
    30541 atatccttca tcactcatat gaggagatgc taataatatt cgtttatttt ccaacttaat
    30601 cccatctttc tatgactttg gtaggtacgc caacattttt agtcttatta ttaatatttt
    30661 ttattactac acttcccgca cctataatgt tcatatttcc aattcttaga ttttgtatta
    30721 ttttagtacc tactccaatt tcatttttat ctcctaatag aacatgtcct gaaatattta
    30781 cacttggaaa aattgaatta taattaccga tttgagtatc atgtccgata gtagagccga
    30841 tattgatcat attgaaattt cctaaaacta cgtcagcagt gtaagtcgta tagggcatca
    30901 aaatattgcc aattcctaac tgaacattta tgcccactag tgcacttgat gcaactaaat
    30961 tagggaaaat caatttatta tttttattta tcttttgata tattttctct ttgatatctg
    31021 gcgaagcgat tcccagaaaa atagcagttt cttcttctaa ttctaataac gagtctattg
    31081 ttcccaatac agtttttccc actaattctt gattttgcat ttttaacgaa tcatcgacaa
    31141 aaccaatcaa ttcatatcta gagaaacttt ctagtagaaa agcaatctct ttgccaaatc
    31201 caccagctcc tacaataatt gctttcactt tactccccct acttattcga agcattcgca
    31261 aaagtgacaa tgtctttagc caattgttca tcgtcttgcg gcaggctctt gacaaattcc
    31321 atcactgttt gcatggaata acctttgatg tttcccacaa agatcttctc gtaaactgct
    31381 tcatcgtttc tttccttatc taacaatagt tcttcatata gtttttcccc tggacggata
    31441 cctgtttcaa tgatttcgat ctcgtcttcg ctatatccgc tcaatcggat catgtttttt
    31501 gctagatcta cgattttcac tggttcactc atatctaaaa taaagatttc gccgcctttt
    31561 gctaacgccc cagattgaat aactaaacga cttgcttcag gaatcgtcat gaaatatcgg
    31621 gtcatacgaa agtctgttac agtgactggc cctccttgag caatttgttc ccggaatact
    31681 ggaatcacac taccgcgaga accaaggaca ttcccaaatc tgacagctga gaatttcgta
    31741 catccttctt cattcaaccc agtcacgatc atttcagcga ttcgttttgt tgaacccatg
    31801 acgtttggcg gattgttggc tttatctgtc gagaccatga cgaagttttt tactttcgct
    31861 gctttggctg cttctgctac attttttgta ccgaaaatat tgtttttgac tgcttctttt
    31921 gggttatatt ccatcaatgg tacatgctta tgagcggctg catggtagac gatatctggg
    31981 tggtattgtt ccatgatctc attgattttc ttgcgatctt ggatatccgc aatgatcggc
    32041 acgatttctg taggacactt ttgatgatgc gtgcgtaatt cacggtcaat caagtaaatc
    32101 gagttctccc catgacctaa aagtaatagt tttgcagggt caaattggat gatttgccgg
    32161 cagatttctg aaccgattga tcctcctgca ccggtgacaa gaatgacttt gtttgtgatc
    32221 tggtctttga tggattcgat atccaactct acctcatctc ttcccagtaa ttccactacg
    32281 tcgatggttt ttaattttga tacgctgatt ttccctgagg caagttcttc catagaaggc
    32341 atcgtattga ctttcacatg agcagattcg actaactcga agattcttcg taattttttt
    32401 cttgataaag aagggatagc gatcgttacc atttggatgt catatttttc gatcaattcc
    32461 ggtatatctt ttaatgaccc cagtactttt tttcctgaaa gataggtatt tcttttattc
    32521 ggatcatcat ccacgaatcc aatgacatgg atatcttgag ccgttttaga accaagaaag
    32581 ctgttgtata aaatacgtcc accttcgccg gccccaacga tcaaggtatt tttagcggaa
    32641 tctgttgata gatacctcat attttttgtt tcgatataga tacgccagat caatcggctg
    32701 ccaatgatca gtaatagcga aagtaggtat gcaaagatca ctaaacgtaa actgtattgt
    32761 ttatttatga aaagcaatat gatgatactt gaggccgcac ttgcagataa cgaaccaaaa
    32821 atcgcaatga tctctcttaa atttgtataa cgattgattc gagtaaaaac tttgaataaa
    32881 ctaccataga ataaataaaa accaatcgac aaaccgatag agattaaaat aaggtccatt
    32941 ggtatagcta caaacggctt catgaattta gctgctgcaa tattcgcagc aatcaacaac
    33001 aagctgtcca caaataccaa tgtggcaatt tttcttcttc ttgttaatac aaacacccta
    33061 cattccccct aaaataaacc aaacttcttc ttttttacct cttcatagac tggataactg
    33121 atctcatccc cgttgatcag gtcctttgcg acttgtttca tctgtgctac tttttcctta
    33181 ccaaagtcct tggcgatttg ctcataacat tcttttaagt aaaaggtacg tttagagacc
    33241 ccatgggcat cggaagcagc catttgcacg aggttatgtt tgaccatcat tttggctgtt
    33301 ttctggatgt cttttccaaa tacaccgaca taacttggtg cggtgagttg agccaagcat
    33361 cccatatcta ggaatggcag caaatgattt gggtcttctc gaaaatgcgc gttgcgttct
    33421 ggatggacga tcactggtgt ctttcctagt tgtaacaact caaaaaagag ccattctgca
    33481 tataacggca cttccagtgt cggaaattcg attagaagat atgtatcatc taaatctgta
    33541 aataaaattt catctcggtg gatgtcttca atcagtgttc cggtaatacg tacttcttgt
    33601 ccttccaata acgtcaaagg caattgtctt ttctctaatt ctgcttgtaa cgaagcgact
    33661 agagaaatga cttgtgattt ttcattgctg tattttccat tattgtgatg gggtgtgcat
    33721 aaaatatgtg tgatcccttg ttgaatcgct ttttcagcca tggcgatact ggcatctatg
    33781 ttttctgctc cgtcatcgat tcctggcagg atatggcaat gtagatcgat catttctctt
    33841 gtctcctctc tttttatttc ttaattcccg tagtaatagc cagcatctct gctgtgttct
    33901 gctccattgt atacaacacc aaggactcgc gcttgtacca tatctaacag ttcttttgct
    33961 ttagtcaatg attcttttcg tgacgtattt tcccgtacga ccaataaggt gccatccgtt
    34021 tttgaagaca tgatctgtgc atctgttacg gcaacgactg gtggcatgtc gaaaatcact
    34081 acatcaaata gttgtcttgc ttctgctaaa atctgatcca ttcttggcga acttagtagt
    34141 tctgatggat ttggtggttt aggtccactt ggcagaatcg acaaattgtc gactggtgtt
    34201 cgttggatct catctgctac acttcctgat gaactaagaa cagtacttaa tccgcttgcg
    34261 ttgttcaact tgaacgtttt atagatgacg ggcttacgta agtctgcatc gactagcagt
    34321 acccgttgac cagatttggc aaaaacaacg gcaatgtttg ctgcagtggt ggattttcct
    34381 tctccaggac ctgatgaagt cacgacaatc gttttgattt gctgaccagc tgcggaggca
    34441 aactggatat tcgtccggat cgtacgatat tgttcggcga ttggtgaaga tgggtttgtt
    34501 aatgtgatca aactgactgc atgagtttga gttgcttttt gtttctgtgt tcgtgccatt
    34561 tttcttcctc ctagactctt gagcggcttc tgcgtgatgg ggctgtttta tcgtttgtag
    34621 cttttggtcg tgcaggagct gatccttttt tacggatacc agcgttcaat tcttttgctg
    34681 acatttctgg aactgttcct aagattggga atcctaatgt atccgtcaca tatttttcat
    34741 ctttcactgt ccgatcaagt aattcgaata agaatgccag acctacgcct accatcattc
    34801 ctaacactaa gccaatcact agattcaatt tattatttgg cgaaacaggt gtcgtattgg
    34861 caactgcacc tgaaataatc gagattttat cgacattcat cacgtctttg gcgttttctt
    34921 ggaaaacttg tgaagttgta ttagcgatct gttgagcagt cactgcattc gtgcttattg
    34981 cctggatcga gaacatttgt gaattttgtg actgattgac ggagatcgca tctttgattt
    35041 gtccagcagt cattttcaca ttgtcttctg tttctaaacg atctttgact tcatttagta
    35101 ctaaatcact gacgatcata tctttatacg tattgatcat ttgcaggttc gtattgacat
    35161 cattgacatt tgctgtgtct gattgtggca gtgtcacgat caattgtgct tgtgaactgt
    35221 attttggtgt caagatgaaa aatgttacga ttcctgagat ggccaagcca gcaaacattg
    35281 agatgatgat tgttaccaag tgtttgcgta atgtttcaaa aatttctttc aagctgattg
    35341 tctcttccat tttttctcca ctttcctatt tattctctag attcatttga tcttttaatt
    35401 cttttttcac acgatcaagt tcttgatcgc tgactttttg ataggagata ttatcttgca
    35461 tgaagccttc tccttgcagc tgatcttgct tgatcgtacc aaatgcctcc cgataatcta
    35521 aagcgatttt tttcatttca tcaaagctca tgtctgtttt catattcgac tctagagcat
    35581 tcaaaacgga ttgatagttg ctgacaccgt ttaaactcaa tacttttttt gctacacctt
    35641 ctacgatctt tctttgacgc tcttgtctac catagtcacc atttggatct tcataacgca
    35701 tacgagaata agataatgcc tgatccccgt tcaatgtaat tttaccgatt ggaaagtcat
    35761 agccatcttg tgagaaagtg aggtcattat tgacttcgat accaccaact gcatcaacga
    35821 gttcctttag ccctttcata ttgatagaga catagtgatc gattgggatg tctacatatt
    35881 tttgtagggt atccatcgcc atggcagctc cgccgaatgc gtaagcgtgg ttgatcttgt
    35941 cttttgtgtc acgacctacg atgtcgacat acgtatctcg aggaatgctg acgatcgttg
    36001 tctgtttgtc ttcaggactg actgtggcaa ccatcatcgt atctgatctt ccttgatcga
    36061 cccgacctaa atctccagta tcaatgccca tcaatagaac agagaaagat tcttgtttgt
    36121 ccagatcaac tggtttcgtt cgttctcctt gggttcgttc cactgattcg taagttttct
    36181 caatagaatg tgagagatcc agatataatt ttgctcctac tcctacaatt gctaatacta
    36241 atacgataag aactgctaaa ataatcagaa atattttttt ccctcttgat tttcttcttc
    36301 gtcttgccat agtttcctcc gtttgctaac cttgcttgaa tcaacgtttt aactgtcaat
    36361 aacttatatt gctatagccc atttgctgag caacagtttg tgcttttgtt gcgtatgctg
    36421 cgcttatttt ttcattccgg atctgctcta tttgactgag cgccgtcaaa tattgatcgt
    36481 aagtagcggt ggcagtcact tgaccatcct tcaacatcgt atcgaataac tgatctagtt
    36541 gcgtgacttg cgcgatctga gtatcagcga atcctagata ttgcataaca accgttttcc
    36601 aaggactatc tttaaaaaag ctcatatttt cacgtacacg agcgacatct gcacttgtca
    36661 ccttttcttt gatgacgaca tcgtctacag cttgctgcca gtttgataca tttttagtaa
    36721 ataaatcgtt gacagctgtc tggatcttca gttttgattc tgcactatct aactgtgtca
    36781 cgattgcttt cttctcatct tggattgcaa cagcttcttt aggcaattct gattctttga
    36841 tgtcgtaatc atctgctgaa agtttgacag aggatagctt atttgacaaa cttgtgattg
    36901 tttcttctgt tatttcaggg tttagaaaat ttttttcttt tgtactatac agcttgtcta
    36961 cttcttttga taaagaagtc aaggtgtctt tttgattggt gatggcagat tctgcataat
    37021 tgatccgttg ctgatgttgc cgctgattat tgatatggta accaaacaaa cagatcgcaa
    37081 tagcacctgc acctaccgcc acagcagtca atgacttgac gaatggcttt tccatagatt
    37141 cactcctaag tattgatgat agataaatta agatataatt cacatacata aaaatgacag
    37201 ctttttattt taaaaaacat aattaaatta atatattcac agaaatattt gtaaacaagt
    37261 tttccctata taatcatacc acaaattgtt ttcttgacta gggcaattta cgatttaaaa
    37321 gtaaataaaa cattaataag ataacaatta atcgatttca tttttatttc cttaattttc
    37381 ataggtgttt tta
//
LOCUS       DACGLI010000027        37154 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.028, whole genome shotgun sequence.
ACCESSION   DACGLI010000027 DACGLI010000000
VERSION     DACGLI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.028"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(99..1229)
                     /locus_tag="IXT22_001448"
     CDS             complement(99..1229)
                     /locus_tag="IXT22_001448"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAQ4862823.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IXT22_001449"
     CDS             complement(1878..3080)
                     /locus_tag="IXT22_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4862824.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IXT22_001450"
     CDS             complement(3140..3343)
                     /locus_tag="IXT22_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4862825.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IXT22_001451"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IXT22_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IXT22_001452"
     CDS             4880..5692
                     /locus_tag="IXT22_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862826.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="IXT22_001453"
     CDS             complement(6716..6868)
                     /locus_tag="IXT22_001453"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862827.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="IXT22_001454"
     CDS             complement(7059..7937)
                     /locus_tag="IXT22_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4862828.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="IXT22_001455"
     CDS             complement(7976..9094)
                     /locus_tag="IXT22_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4862829.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="IXT22_001456"
     CDS             complement(9091..11190)
                     /locus_tag="IXT22_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAQ4862830.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="IXT22_001457"
     CDS             complement(11241..12062)
                     /locus_tag="IXT22_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4862831.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="IXT22_001458"
     CDS             complement(12059..12868)
                     /locus_tag="IXT22_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4862832.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="IXT22_001459"
     CDS             complement(12889..13383)
                     /locus_tag="IXT22_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4862833.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="IXT22_001460"
     CDS             complement(13395..13883)
                     /locus_tag="IXT22_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4862834.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="IXT22_001461"
     CDS             complement(13960..16656)
                     /locus_tag="IXT22_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4862835.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="IXT22_001462"
     CDS             complement(17084..18157)
                     /locus_tag="IXT22_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4862836.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="IXT22_001463"
     CDS             complement(18154..18981)
                     /locus_tag="IXT22_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862837.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="IXT22_001464"
     CDS             complement(18982..19788)
                     /locus_tag="IXT22_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862838.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="IXT22_001465"
     CDS             complement(19800..20885)
                     /locus_tag="IXT22_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862839.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="IXT22_001466"
     CDS             complement(20902..21444)
                     /locus_tag="IXT22_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4862840.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="IXT22_001467"
     CDS             21702..22691
                     /locus_tag="IXT22_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAQ4862841.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="IXT22_001468"
     CDS             22688..23425
                     /locus_tag="IXT22_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAQ4862842.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="IXT22_001469"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="IXT22_001469"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAQ4862843.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="IXT22_001470"
     CDS             23989..24621
                     /locus_tag="IXT22_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4862844.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="IXT22_001471"
     CDS             24706..25353
                     /locus_tag="IXT22_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4862845.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="IXT22_001472"
     CDS             25358..26341
                     /locus_tag="IXT22_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAQ4862846.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="IXT22_001473"
     CDS             complement(26744..28258)
                     /locus_tag="IXT22_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAQ4862847.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="IXT22_001474"
     CDS             28396..29202
                     /locus_tag="IXT22_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862848.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="IXT22_001475"
     CDS             complement(29377..29946)
                     /locus_tag="IXT22_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4862849.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="IXT22_001476"
     CDS             complement(30029..32089)
                     /locus_tag="IXT22_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862850.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="IXT22_001477"
     CDS             complement(32366..33844)
                     /locus_tag="IXT22_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4862851.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IXT22_001478"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="IXT22_001478"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAQ4862852.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="IXT22_001479"
     CDS             complement(35150..36070)
                     /locus_tag="IXT22_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4862853.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="IXT22_001480"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="IXT22_001480"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAQ4862854.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT        11108 a         7694 c         6275 g        12077 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgggccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agat
//
LOCUS       DACGLI010000028        36009 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.029, whole genome shotgun sequence.
ACCESSION   DACGLI010000028 DACGLI010000000
VERSION     DACGLI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.029"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            44..379
                     /locus_tag="IXT22_001481"
     CDS             44..379
                     /locus_tag="IXT22_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862855.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
     gene            complement(636..2219)
                     /locus_tag="IXT22_001482"
     CDS             complement(636..2219)
                     /locus_tag="IXT22_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862856.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            2341..2925
                     /locus_tag="IXT22_001483"
     CDS             2341..2925
                     /locus_tag="IXT22_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862857.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2936..3181
                     /locus_tag="IXT22_001484"
     CDS             2936..3181
                     /locus_tag="IXT22_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862858.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            3187..3909
                     /locus_tag="IXT22_001485"
     CDS             3187..3909
                     /locus_tag="IXT22_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862859.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            4040..4783
                     /locus_tag="IXT22_001486"
     CDS             4040..4783
                     /locus_tag="IXT22_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862860.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            4789..5154
                     /locus_tag="IXT22_001487"
     CDS             4789..5154
                     /locus_tag="IXT22_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862861.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            5170..5700
                     /locus_tag="IXT22_001488"
     CDS             5170..5700
                     /locus_tag="IXT22_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862862.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            5862..6170
                     /locus_tag="IXT22_001489"
     CDS             5862..6170
                     /locus_tag="IXT22_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862863.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            6166..6585
                     /locus_tag="IXT22_001490"
                     /pseudo
     CDS             6166..6585
                     /locus_tag="IXT22_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6722..7522
                     /locus_tag="IXT22_001491"
     CDS             6722..7522
                     /locus_tag="IXT22_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862864.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            7559..7741
                     /locus_tag="IXT22_001492"
     CDS             7559..7741
                     /locus_tag="IXT22_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862865.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            7852..8169
                     /locus_tag="IXT22_001493"
     CDS             7852..8169
                     /locus_tag="IXT22_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862866.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            8172..8404
                     /locus_tag="IXT22_001494"
                     /pseudo
     CDS             8172..8404
                     /locus_tag="IXT22_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8519..8998)
                     /locus_tag="IXT22_001495"
     CDS             complement(8519..8998)
                     /locus_tag="IXT22_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862867.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            9118..10455
                     /locus_tag="IXT22_001496"
     CDS             9118..10455
                     /locus_tag="IXT22_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4862868.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            10478..11005
                     /locus_tag="IXT22_001497"
     CDS             10478..11005
                     /locus_tag="IXT22_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862869.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            10992..11555
                     /locus_tag="IXT22_001498"
     CDS             10992..11555
                     /locus_tag="IXT22_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862870.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            11977..12714
                     /locus_tag="IXT22_001499"
     CDS             11977..12714
                     /locus_tag="IXT22_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862871.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(12731..13147)
                     /locus_tag="IXT22_001500"
     CDS             complement(12731..13147)
                     /locus_tag="IXT22_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862872.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            13540..14787
                     /locus_tag="IXT22_001501"
     CDS             13540..14787
                     /locus_tag="IXT22_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862873.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            15055..17445
                     /locus_tag="IXT22_001502"
     CDS             15055..17445
                     /locus_tag="IXT22_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAQ4862874.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            17494..19329
                     /locus_tag="IXT22_001503"
     CDS             17494..19329
                     /locus_tag="IXT22_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4862875.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKSVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            19404..20261
                     /locus_tag="IXT22_001504"
     CDS             19404..20261
                     /locus_tag="IXT22_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4862876.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            20251..21360
                     /locus_tag="IXT22_001505"
     CDS             20251..21360
                     /locus_tag="IXT22_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4862877.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            21699..22499
                     /locus_tag="IXT22_001506"
     CDS             21699..22499
                     /locus_tag="IXT22_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862878.1"
                     /translation="MVGVSKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            22587..23393
                     /locus_tag="IXT22_001507"
     CDS             22587..23393
                     /locus_tag="IXT22_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862879.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVEEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            complement(23415..24842)
                     /locus_tag="IXT22_001508"
     CDS             complement(23415..24842)
                     /locus_tag="IXT22_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HAQ4862880.1"
                     /translation="MMRKQSIEGRNQFAMLTIDDLVPKDHLVRKIDAAIQFDFIYPIV
                     ESTYSTYGRPSIDPVVLIKLVFIQYLFGIRSMRQTIKDVETNVAYRWFLGYSFEDPIP
                     HFSTFGKNYVRRFRETTLFEDIFSHILEQAVKAGFVTEDNLYIDSTHIKANANKHKFT
                     KEMTYGQAKAYQDELEDEINKERIAVGKRPFTWDTESELSLQKISHSDPESGYYVKGE
                     REKQFAYSAHTSCEDNGFILSTLITPGNVHDSQVAIDLVKQSKRAFPNIKRVVADAGY
                     KTPKFVHFLSHLKLYPILPYTAPHGVKGMFRKKDFVYDAYFDCYLCPNNQPLLFSTIT
                     RDGYRTYKSNPKFCVSCPLLENCTLSTKHQKIVTRHIWADLMDELEHQRHTALNREIY
                     KKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLTFAAMNLKKLATWLWKTKKPM
                     AFYFKIMQRLTKRSGLITNSFLSTI"
     gene            25163..26032
                     /locus_tag="IXT22_001509"
     CDS             25163..26032
                     /locus_tag="IXT22_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAQ4862881.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            26052..26399
                     /locus_tag="IXT22_001510"
     CDS             26052..26399
                     /locus_tag="IXT22_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862882.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            26412..27674
                     /locus_tag="IXT22_001511"
     CDS             26412..27674
                     /locus_tag="IXT22_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862883.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            27754..29130
                     /locus_tag="IXT22_001512"
     CDS             27754..29130
                     /locus_tag="IXT22_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAQ4862884.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKVEQGAKTLEKLQAEKLEKVLRALGK
                     ADPEPQTSNNTNNKQPIASKTKPKANDPKGSENVVITTDKSEKKQINGSTSPIMQKML
                     KAKKQVHK"
     gene            29127..29756
                     /locus_tag="IXT22_001513"
     CDS             29127..29756
                     /locus_tag="IXT22_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862885.1"
                     /translation="MIIVSSFLRWLTPYKYTDEVVVKRAKKRDKKAVLTPKQMLDHGI
                     LGVKVLEVNKPFESNSAREKLLGAEADVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLRPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSNQNRVQINKFEKKVRK
                     FNDRKTILWFADICKQPDGTAKWEAVIFDENGKKVMSETWHDKAKFVWQ"
     gene            30574..30627
                     /locus_tag="IXT22_001514"
                     /pseudo
     CDS             30574..30627
                     /locus_tag="IXT22_001514"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30631..31230
                     /locus_tag="IXT22_001515"
     CDS             30631..31230
                     /locus_tag="IXT22_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4862886.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLHSNIVSMGLSGGIFGWIALFAIAYIRFDSKKHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            31246..31722
                     /locus_tag="IXT22_001516"
     CDS             31246..31722
                     /locus_tag="IXT22_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862887.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            31739..32641
                     /locus_tag="IXT22_001517"
     CDS             31739..32641
                     /locus_tag="IXT22_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862888.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            32714..32905
                     /locus_tag="IXT22_001518"
     CDS             32714..32905
                     /locus_tag="IXT22_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862889.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            33069..33656
                     /locus_tag="IXT22_001519"
     CDS             33069..33656
                     /locus_tag="IXT22_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862890.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            33656..34555
                     /locus_tag="IXT22_001520"
     CDS             33656..34555
                     /locus_tag="IXT22_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAQ4862891.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            34555..35469
                     /locus_tag="IXT22_001521"
     CDS             34555..35469
                     /locus_tag="IXT22_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862892.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            35521..35736
                     /locus_tag="IXT22_001522"
     CDS             35521..35736
                     /locus_tag="IXT22_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862893.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT        13409 a         4992 c         7061 g        10547 t
ORIGIN      
        1 aatttcctag gaaaaatagt taacataaaa ggaatgaatt gttatgaaac aatatttaaa
       61 tgaatggaaa gcgatagagg ggtcattagt aacgcaaaga ataaaggaat tacctgattg
      121 cttagagaag gatcatttgt ttcaaatacg agaaatgttg aaaaaagaac agtttgatcc
      181 agaccaattt ttagtagtcg agtatccaac tattggagtg tactgttgta accatatcaa
      241 tgatggaaaa tattttatta ttcaggagta tggaggacag ttaactcctt tctatactac
      301 atgggaaatg agtgaagaag gaatcaataa ttttccatgt gaaagcatcg aagattcaat
      361 ttcacacacc gaatgttaat tgattataac tataaaaaag gattgaacat tatgttcaat
      421 ccttttttca atgaaatgtt ttccgccatt tcattgtttg gtgcgatttc tattttatta
      481 tatcaaaata aagagagatt ctaaagaaag aagagggaaa tatataaatc aagcgacagt
      541 atatttatta ttaaatgcta ttgtgagaat ataactaatt agtttaattt gaaagtaaat
      601 atacgctata aaagtgcatc ttgtgttata aaaaattatt ttattttgtg aacataattt
      661 aacaattctt tctcggaatt gatttctttt cttaaatagt cttcagactt attaataata
      721 ttatctatta tgtctagata catatcactt ttcgattcag ctaattcata cagttttttt
      781 aattctttat cctttaattg aaaaccctga tccatagtca ctgcatttgg atatagaagc
      841 ccactataat gtttacgtaa attcacttgg aatttctgat tataaaagtc taacagatta
      901 gaaataaaag gcggaaaatt actgtttttg taaaattgat tatttccatt taggttgtat
      961 agtaatttgt taaattgctc ctgatttaat ttattgtaaa tccatggtaa tacttccata
     1021 tccttatctg ctaacctgaa tgaactagca tcggtaagat gttcgatcat aaaatctatg
     1081 aacatctctt tttcaccaaa atataaatat tgattatata ttgtttctaa tgttgaagat
     1141 ggtagcgaag aaactctcat tttttgctgg agtataggat caactagact atttaagtga
     1201 ttttgtaatt cttcattgtt gtttcctaga actgcaaggg aacgtaaacg gtagtaatat
     1261 tctatttctg ttagtacttg ttgtttcggt ttaaaatcat ttattgatat ttgtaaattt
     1321 tgaattgtct cgtctgaaaa atcatgttgt aattctggat gggtagctat aaaagtaagt
     1381 aaaaagaacc cttttgtata cgtgatctgt tgattttcac caagtgattt attaatttcc
     1441 tctcttgatt cagctgtgaa cctatacttt gcaatttctt tttttagaat atttaaatag
     1501 aattctttat tatcaaaaat tagggcatta agtagtctga aagtactttc cctatctcta
     1561 tctgcttcct catttccata agataattga aaaacaaact taaaggctgt cttacatagg
     1621 ttttctttgg ctttttcgct tagtttattt agatagctat tttttagtgc agagtgaaat
     1681 tcttcaggtg taacagacat agcatgtatg cgacttgcat attgtataat ttcgatcgtt
     1741 actttttttc ctaatattgg attttttagg aatataattt cataggactt ccgtataaca
     1801 tcctgacaag tttcttttgt tatatctctt aattcccaag tattaccgtt gtaagtgact
     1861 acaggatgag ctgaataatt tctttgatcc ttaatatatt ttaaatcctc atattcatag
     1921 ctatcaatta gctcagttga actataagct ttttctagta gttccatttc ccattttgga
     1981 gagtttggat cactttttct tagtctagct atatcttcta aaattttctt agaagtatta
     2041 tcctcgtaaa tatttgctaa atcagataat ttatcaatta aatctaaaat aagcgcactg
     2101 taattgacag ctattgcaga acgataattt ccctgataaa aactacttct aacttcttct
     2161 aataatggaa taattctagg atttttaact ttttttattt catcatctaa tataaacata
     2221 taaatctcct ttttttattt gtatgacaag tttaccataa aaaaaaatta aaaagcgaga
     2281 catatttatg ttgttgtgtt atcataataa cataaatatg tagagtgaga tgatgaaaaa
     2341 atggatttga aacaatcgtt ttacatctgg ttatatcctg ataatcctat gtcaataatg
     2401 gctgatattt ttgtagttag catcttattg tatttatttt atctaatttt ctttcacaat
     2461 ttaatcgggt acatgattct tgattggaaa ggaatgttcg atatagaaag aaaaccattt
     2521 gctaacaatc aaacctatac cgtcttcgaa agtggagatt gggaagaaaa tgaagttgat
     2581 gtgatccatg aaattggatt agctttatca ggaatacaag atgctgatgt tttggtatca
     2641 atgacaacgg atactggata caacgcttat gaggtatttt atcttatgta ttttatatgg
     2701 cgtgatggtc aagaaattat caatggtcgt gctgaaaaaa caatcaattc taatactgaa
     2761 atttcttttt gtatgggtga aggggaaatg attgtatata aagatgggtc agcaaacatt
     2821 aaaacagcct ttggtgatat tgaaacaagt attaaggaac ttagggaata tgtgcagaac
     2881 ccatataatt ttcaatattt agcaggaaga ataaatttag tttaggagta aaaatatgaa
     2941 aaaaattata aatcaaccaa caaatcactt gataattgaa ggtgttattt tcgtaacaat
     3001 gtattttact gtaggaaatg gcatctcaaa tacaatcatt caaaaaaatc cacaatacct
     3061 attatttagt ctttatgctt ggattgtaca aatggtttgg gtttccatat tgatgctgtt
     3121 gttttattgg atagtacggg ttattctttt attgttaaac aaaagaaaaa aggataggtg
     3181 aataaaatga aatcaactaa attgaaggtt gtattgttat cgacagcagc attaataacc
     3241 cttacagcat gtggtacaac taatagtgct aataataaca aagacacaaa gtctagtagt
     3301 acgatggtta ctaaaaacag cactacatcg gcatcaacaa caatgtcttc aatgactgaa
     3361 aataatgctg aaaagtatca aaaatacgaa gacattaata aaggtcaaaa gccggatgaa
     3421 gtttataaca actttattaa tacagtaaaa aatgatgaaa attatgggaa tgatccattg
     3481 caaaataaaa atctgactat cgttctttac aaacctgatt gtccagattg tcaaaaagca
     3541 gaatcaaaaa tcatgcaaga aataaaagaa ggatttagtt atgctccaac attaatgcat
     3601 gatattacca taaataaacc agcttacgag tattacgcag ttgctgtaga tattactgat
     3661 ggtgtacctg agtgggtaca aaacattcct ggtctggctg atgagaacaa tcaatatcat
     3721 acgccaacag ttgcagtagt aacaccaaag aaagttaacg gcacactata ctgggatgta
     3781 atgggaatga caacaaatac aactgatgaa atgattgaaa gtacaactaa atattatatg
     3841 gatttgggag catataaatt atatcaacaa tcagagcctg ttatggacga tcaatccaaa
     3901 gttaaataga tctttagggc gtaagcccta tttttttaaa attaagtgat aacaaataaa
     3961 tgatttctga aacaaacgtt cttactcaac tactcgaaac acacaagcta attaactaga
     4021 ttataaagga gaatgcgtaa tgaaagaaat cagtgcaaat gaagctcata ttccgcaaaa
     4081 gaatcaggtt ggtatatata aggtgcttca tggtgaagga atttataaaa tacagttact
     4141 taccggttac aataatggtg caaatgggaa gtggttaaag gcaacaagta ttcgtgaact
     4201 tagaagtgaa gtagaaaaaa ttaggcttgg tctcacaagt gaagaaatag ctaaactgaa
     4261 gggaaataat tcttttgtaa ttgaaaaaga aaaggaaaaa catctacttt atcgtgagct
     4321 gaaaattgaa gaatactatg aaattgattt acctgaaaaa ttaagaatta ttgatcaacg
     4381 ttcagaagaa aaatggaaaa ctgaaatata tccaagctta aatgactaca agacatcagg
     4441 aaagcccatg tataactaca caggcttttt aacctacaca caatacaaat atgcctttcg
     4501 caaattaaaa ggcattaaac aagctgaaat tgccctgtat gagatgaaaa aagtggatag
     4561 attgaaattg attcaagatt tagtgcaaaa tacatggaat caagcgattg tcgagctaga
     4621 aaaagaaaat gggaaaattt taactaataa atatctgatc gtaaatgaaa ttgaagaatt
     4681 aattggttta ttttcatgtg aaaaaggtga agtcttcttg aagtcatcac caacctattc
     4741 aattttggac agtccgtatc agtttataca ggcaaggaga tgagttagat gtctagcttg
     4801 aaagatgact atatccaagc aaaacaagag tatgaaaaaa tacagatgtt gaaatctgag
     4861 aaagtcgaat tatttttaac acaaaaatta gcagaggatc atattgctaa cttagatgct
     4921 aaaactttag aggaatatga tcggcagttt aatcagatac atcacaatat cattttgctt
     4981 gttgagcagg caaagcgaag gtttgaaaaa gcggaatatg atctattaga tcaaggaatt
     5041 gtatgcttgg ataagggatt gcgaagatat tatggtgcag agttaaaaaa gcaaaatgta
     5101 gatagaaatg cactaaaaca tgaaatctta gaattgataa tgcaacgaat ttgaagggat
     5161 agaaagcaaa tgtcacaaaa cattagtgct gtaaaacaat taatagaaga agatttagag
     5221 accacagttc agagattagc ggaacgaatc cattttgcaa attatcaaac catctctaac
     5281 tggtcaagca ggaacagaaa tccggaagaa attccaatga aattttttta tcgaatcgga
     5341 aaagaatatg gtgttgatcc gataaaaatt ttcgagaaga ccatgattta ttactatcat
     5401 ggaacaccta acgaagtgtt agaacatctt ttggaagagg caaaagaaaa atcatcaata
     5461 ttagagctat cgcaaaatga caaagttatt caagtgaaat gcgttgatcc aacaggaaag
     5521 attattgtcg gttttgatat tgaaagaaaa tccaaaatag attttattac acaattaaaa
     5581 aagataaata atttagatat tctaacgctt agaccagatc atgaacagtt gtttatgagt
     5641 tttaaaaaac aattgaaaga aatacaaaaa agatataaca aggtgtttcc taatgcgtga
     5701 aaagctcaaa gaaatcagag ttttttggat aattaacaaa gaatgtatca tcttatatac
     5761 tcttggattt cttagcatga tcttgttttg gtggttatat ttaaaacagt aattggagag
     5821 ggtcaagagg atttttatca agataaggat gtggaaactg catgtggaat aatagattaa
     5881 aaacaggatt gttattaata gttatttcct gcgctatgat gattggtatg aggatacaaa
     5941 gggaacaatc ctattttgaa gtttctgcta acaacgtaat agaaaaatgc tattacggtc
     6001 aacattattg gagtgaggaa gtcagagaaa atatagatcg tgaatatgtt caaagaattg
     6061 tttgggatgc atattctatc aaagattatc ctaaaagttt aacgagtaga ttattttaca
     6121 gtgaaaaaga taatcaaaaa ctctcagatt tgatgatgaa aaaagtatga ctattattac
     6181 gaaagagaaa cagagtgcta tattcgaggg gaaaaagcct acaacaaaag tgactattgg
     6241 ggtgacaagg cgaagcgatt aactgcaaat tttagagtgt atgaatcaga gtttataaac
     6301 ttgacctttc ttaatagtgt ttttattgat tatgtaatta ctacgaaacg cattggaagt
     6361 tattcaagta cctacgcatc cttagttcca atgttaaact cgatgagccg tttcttaaaa
     6421 gaaagagaaa agaaagagct acagtatatc aaagaaatca tgccggattt tgaaatgcac
     6481 gaatggcaaa ttgctttatc agattggaaa ttggcgaata aggttcgtag aataacacct
     6541 tttcaagcca agcgcttttt gagagctatg aaatttgtgc aataaaaaaa gccaccagac
     6601 aagttgatgg agactaacac aattaccaac agttgtaatt gtgttagctt acaaattaat
     6661 tatggtgttt agtcaatccc aaattgtgaa atggcaccaa taattggaaa ggaaaaatga
     6721 aatgtctgaa gatttacgag agctgaagtt acgaaagaag cagtatgatc agtatttttc
     6781 cggtttgttg aataaacata ttgaagaagg acttgatcat gattttggaa aagatgaata
     6841 ttgtttatat tgcgaacgtt acaatgaaaa aatgtctgaa tatctacagc tgaaaaaaga
     6901 gatacagaaa ttagagaaaa aagtacatgc ttggaagtat aaagattcca tgtctggtta
     6961 tgttgaatct caaaataagc caagaaaaaa gaagcaagcg tatgttctaa agatggtaaa
     7021 tggggaagag ttaattgtat tagcgtacag tgaagaagag gttcgagaac tcgttgaaac
     7081 acctgtcagg aaaaaggttg aaacaataaa tgagatagac gacagccaat acaatagcat
     7141 ctatattgaa acaagtcatg gtggatataa gaaattagca actttcctta gaagttctaa
     7201 agttgggata atttctaaaa aagacataag tgctgttacc gatagttttt gtactttatc
     7261 tgttcctaaa gcttatttcc aatacgatag taaaagattt gaacgcttag agaaattctg
     7321 tagaccgtat actgtattga aaactaaaaa atttaataaa actaaaagag tttctataca
     7381 gttaccgact ggtcaaatct cattaggtga aaaagactat ctgataaaag taggaaaaga
     7441 gttaattata aaagtaccgg aacacttatt taaagaaaat tttgagatac gtgaaacctt
     7501 ggtatggaaa gaagaaaaat agtttggaag acatagaatg gtataagggg aaattgaaat
     7561 ggcagtaaat aaaatattgc aggtactaat catagacgaa tttggcggag gagaatggtt
     7621 tgatgtgcag tccatagact ttgaagaaga agtcgtagtt atagaaaata tttacggcga
     7681 agtatattca tattcgcttg aaggtgagaa tattgaggat ttacggttga ttggtgagta
     7741 gaaaaaaaca gaaatatcaa aatggagata aaaattaata gcatgtaaag atagtcatgc
     7801 ttgggttaaa aatgttaaaa ttcaaaaaaa tgagtcagaa gggataaaag tatgaaaaga
     7861 gaggaataca aacaaagatt aaacgaactg cttgaagagg acgaaacatt aactcatggt
     7921 tcgcctgatg aaattctata catgattgat aatatggtga tctttggtgg atatgaactt
     7981 ggtaataggt cagttgatca taatatttta gaatttgatg atgtatcatg ggaagaaatt
     8041 cttgattggg gaattttggc ggtacctgaa actaaaacct atattagtga cactatggtt
     8101 cctttttttg aggaattgga ttataaaaga cttcccaaaa atgaaaatca tatactggga
     8161 ggaaactaac aatgttaagt gacttattta ttttactgat ctatctaggt gtaagtgaaa
     8221 ttattgcgta ttttttgttt gtcattgcta attatggtat ttccagtgca atcgttcaaa
     8281 tgtttagatt accagtaagt gaactaaaaa aatgatgaga ttatcagcat atcttttaat
     8341 gtttttgaat gtggtcacgt taatctttgt agtaatcggt gtgactttcg atttaatgga
     8401 atagtgggaa atctataatg gaaaaaagag acacgaatga acatattttt tgaatcaata
     8461 ttgttgatgg tttttgcgat cagcgcttac cagaaatcta aaaaagagta atgattgttt
     8521 aatcatcact ctttttttgt agggaaattg aaatatgtgg agcttgtatt ggtttagtta
     8581 ggattgcttg gctataagga gctagttctt tatcaaaacc atcaaagtag gttttcagta
     8641 gcgatttaac tgatcgctca tcttgtttga tttggataat ttcagcatcc aaatcggttg
     8701 tgagatcagg agcttttgat gcgattacct gatttttttt atcttccaac tctcttaggc
     8761 tgtttaacaa gttgtaaaaa gaatcatttt gattgttcat tccaacgtga gttgcaattt
     8821 taacagaagt ttcgtccgta ttgtcatcaa aagaactcat tggaatatca agtagtaacg
     8881 aggatgtttc ttttactgac tttttcttta cagcattttt tgtttttcca tcttttttgc
     8941 tctttactcg agatgttttt ggagctagtt taggtaaatc acttgtttta tcagtcattt
     9001 attagctttt cctttctatt aatttatgtt attatattat cataataaca taaaaaagta
     9061 cactttttgg gggcgtagtt attgaaaaaa tctaagagaa agattgccac attgcttatg
     9121 ttaatggtgc aatttacagg gattgcaatg agtgtaatca caataaatcc gcaagtgata
     9181 catgctgatg ggatagctac ttatgatgca caatttaact gtactactga aggtagtggg
     9241 tcaggaacag atagcgatgg aaacgatact ggaagtggcg ctgtaacagg tgatgtagcc
     9301 aaaaatattg aagatattta caaatacatg aatggagaat atggcttatc aggtgctagt
     9361 attgcaggta ttttaggtaa ctggaaacaa gaatcaggta ttgatcctcg agcagtagaa
     9421 gggtattacg gagatggaca gagagaagtt gacttcatca aacaatttac tgatggtctg
     9481 atgggtattg gctatggtca atggacagct gggcgacata cagcattagt tgattggtct
     9541 aagaaaaata atggcggttc ttggtggact acagaagccc aattggactt tatgttcaaa
     9601 ggtgatgggg gattcgtagg aatattaaaa gattatgctt taaatgcttc tgatgatgtc
     9661 gtagaaaatg cagtaacttt tcataaaaac tgggaaattt cagctgattc cgaatcagct
     9721 gtaatagctg tacgtggtga aaatgcaaaa gaaatctgga agtacatgaa aagcaagggt
     9781 atggacggtg caaaagatga aagtaagatc aataaaatat ccggaggttc aagtaccgga
     9841 gatggatcga ataattcatc aagttcagca tcaggaacag tagaagatgc ctgtgcaact
     9901 acggatgacg ctaattctgg ttctggatca attgggaaag aaggaaaaat taacggtaaa
     9961 aaaggtcaag taatagcgaa tatgacttat gaagaagctt tgaaaaaata tgggaaagcg
    10021 atcacgctac caaaattcaa agaaccagat tggtcaactt caccttttaa cggaatatat
    10081 caaggtcagt gtacagagtt gacgtgggct tatatgagcc aattatacga tgggaatcaa
    10141 ccgactactg gaaatggtgg ttatgtatgg gaaagctaca aatcggcagg agcaaaaata
    10201 acgaacaaac caatcgtagg ttatgggttt agtgcttcgg atggatggtt atgggctgtt
    10261 ggagatgcag ggcatactgg tgtagttata gcggtgtttg aagatggatc atttctatgt
    10321 gctaacttta atgttccacc aacccaagct ccaacaaggg gagtttcggt aacgttgatt
    10381 gatggagtgg acggatcaga taatgtgcat ttctttagcg gtgtaggaaa agctaaattt
    10441 gaaatcgaaa aataaattgg aatgaaggac gatatagatg aatagtaaag tgaaagatac
    10501 aattatcatt tctttgcttt ctggtatgtt attagcactg cttgttggaa tcctattctt
    10561 caataagcag aatcaggaca tagaagctga aaaacacagt gtgcatattg aagataagct
    10621 gacattcttt aaagaggtta aaccaaatga ggtggatgga ttacggaaag atttagaaaa
    10681 tgatattcaa gaaatgttga atggatcagt tcaaaataag tttgcagatc aatcaggtga
    10741 agaatttttg agaaaactat ttattgtaac aggtaaacca ccaattactg ataagagtag
    10801 tgagaaagaa aaaatcgagt actataagcc ttttactttt aagctaacaa actttggaat
    10861 taagacatct agtagtgggt tgtatgaagc attgaccgat tttgaagttc aatacaatgg
    10921 aaaaaaagtg tatgatacca cattaaccat cacactaaat aatgataaga aagtgactgg
    10981 gggtgctttt tatgcaaaat catgaaatca ctactgctaa aaaggcgatc ggaatacttt
    11041 ccataattgt gatcctttgt tgtgtggtac tatttcaaaa gaaaaatgct tatgataata
    11101 atgtcaaaga attggaagac cttaaaagta aacaaatcga agtagtcaag aataaccaga
    11161 aagtgaaagc tatgcaggaa gctcaataca aagaattggg aaatgctgaa attaaggaac
    11221 aaagtaggaa attctttaat ttattttaca actggaattc atgggaaaaa tatacgaaga
    11281 atatgaagga aatacaaaaa gaatttcctc agatagtaaa gtctagtcct gttgatattt
    11341 ctggcacgat ggtaggcact ggtaatagtc caatatctag ctatactgct gattactata
    11401 caacaaatca aaaaggtaaa atggttgaat tgattacaca gacaagaaat actccaacaa
    11461 cagcaacaac aacaatttgg cgtggagtaa caagcatagg agaaaatcaa ttgttttatt
    11521 tggaggattt agatagctat gtaagagcag agtaaaataa aaaaagagct aacggtacca
    11581 acgttagctc tttgtgctga cgatgataac aaaacctacc gaaaaaggat tgtttcatca
    11641 caaacacaaa cagaaaagaa ttgataaaaa acccgaacct cagaattttt attaatcaat
    11701 tcatttagat tataataaat tgagctgaac attacaatac gtatatgttg taaaacgtaa
    11761 aaaaagtcaa aagtaaatac tttcttaaaa agtcaaataa aactattaaa gacaatatat
    11821 atggtttatt tgacataaga aaatggtcta gatgataatt gtaatataga attgtagact
    11881 taaataaagc ataaaatacc ttttatgata aggtatagct cttaatttta agcagtttta
    11941 gatataagat tgaaagtaaa gtgggggaga ataataatgg cagatcataa attagaaaag
    12001 ttattagaag aaacgtggaa tccaaaagaa tttagtgaat tttttatgga gaattttgaa
    12061 actgacttag cagtgattgt taaagatgct cttagagagc aagggtatcc tgaaactgca
    12121 aactatataa acattaattt tactttgtat actgaaaata aaggaacttg ggatttttgg
    12181 gctactttag caaataagga gttaagtgat aaatcagaca caggaattcg taactttttt
    12241 gaatcaaaca gagatgatta tatgtatgct aacaatcaaa ataaattgaa ctttagagta
    12301 gagtttgatg aaacacctga agaatttata gaaagacaac cgcctaaaga aaatgtagca
    12361 aaggtattgg aagatcgttg gaattcagat gaaatagttt caacaattag cgaactaggc
    12421 ggacaatatg aaccgctagt agaagcggtt agagaagagc taagactgaa taagtttcct
    12481 gatgttcaaa atattgatgt ttctcaaatt gaaataaacg tcaagatcac gaataaactt
    12541 gattatggta gttgggcaga tatagcatta gaaaaataca tctactcaac gttaaaagag
    12601 tttatcgaaa atagaatgga tatcatgtat ctacagcatc cacagtattt aaactttggt
    12661 gttgaaatag ctacacctct tgaagaatgg aaaatggagc aagggcttga ctagcctttg
    12721 ctccattttt ttattttaca aatgaataca gttcgtcgtt tttaccaaga atgattgttt
    12781 gcccaacttt gagattgtca ggtgatcctt cagcggtttg taaggagaac gttccattga
    12841 acttatcgga taccgttata ggtagcttta attctgatcc ttcctcatct ttgagaattg
    12901 ctgtttttcg ttcatcaaaa taaacagtct ttattaaata atttttcgta gtgatctcag
    12961 cagatttgtc tttttttgta gtagtaccag tttctttaga attagaggta ttttctacga
    13021 ctattccatc tttggcattt gagcttgtgt ttatttgatt gaatattttc agcgacaaga
    13081 taacgctaag aatagtcaat atagaaacaa gtgtaattaa tactgataat ttcctttttt
    13141 tgttcatttt ttcttaacat ccttttttgt tttgattagt tagatattcc ttatctaaca
    13201 agccttttta ggctattaaa tgaagataaa ccccaaaaaa atattgcaat tatgacagtg
    13261 caatggtact attattatac aataaatttt gcgaaagggg taggtctaaa tcgcaaacaa
    13321 aaagaaattg aacctagaca aatacaactt gtataccgca agggaagcaa gtttgatttt
    13381 gggtaaaggt agaaattatg ttacaaacat aatcaactat tatccaaatc gtttgcctaa
    13441 aggttcgttc aagaaagtgg gtgacaaaac ctatattata acggaagaag gaatagaagc
    13501 attgcgatca caaacagaaa ataaaaacaa aaagaaggaa tgaatatgaa gagaaattcg
    13561 cttggtatgg ttttattggc atcagctgta cttgcggggt tatcagtacc agtaacctca
    13621 catgctgatg aatggactgc aaacacaccg gatcaaatcc aaattacaac aggacaatca
    13681 agttatgcgt tcaaaaaagg agatactatt tggtcaactg tagagaagct taaaagctta
    13741 ggttacaaga ctactgttgc tgagtttgcc gaattgaaca atgttgattt ggcaaaagga
    13801 gaacaacgga ctatcccgat tggacgaact ttcaacatca gtaaagatac attaacagtt
    13861 aaggaagcag atggcgaagt agttagtcaa actgttcaaa aagataaacc tgatcctatt
    13921 gaaaatacgg agcaagagaa caaaaaatcc gagactacaa aagaatcgga accaacagca
    13981 aacacttctg ataagacaga aacaagtgct tcaagtgttg atggagcaag ttcatctaat
    14041 acaaataatt ctacaagtga gaaagaagca tcacagggaa caagtgaaag tagcactacg
    14101 gaagctgata ctggaacatc aacaaataac tcacaatcaa catcaaatga tgcaaatgaa
    14161 tcaaccagta catcttctag tgatcaatca caaacaggtt cgagtgatga aactgacagt
    14221 tctacttcac caagtaaacc cgaacaacca actaatgttg tgctaggcgt tccatttatt
    14281 agtcaaggta acacaatgct ttgcgaagga acatctttgc tagaagcgtt acattataaa
    14341 ggtgttgcaa caaatcaaga tttaatgact tttgttaaat caatgccact atctcctgac
    14401 aataatccaa ataatggttt ttctggtgaa tggagacaca atgtggatgg aacttatcaa
    14461 ggtatgaatc cggctcctgt agtttcatgg ggtgttgcta atggcggaaa tgttgtagat
    14521 atttctggtt catcggtaca aggattaaaa gatgagattg taaatggaaa tcctgtagta
    14581 gcgtgggtaa cttatgcctt tgaacctgct caacataaac caatgttttg gggcgatgct
    14641 atttggaatc gacatgtagt agccgttgat ggatttaaag acggttttta ccatgttgtc
    14701 gatcctgtgt ttggggcaag ttggattaat gcaggatcat ttgaaacagc atataacgta
    14761 tctcaattag cggtttcggt acgttaataa aagatatcgt ttatatacta agtagttata
    14821 tagtctttat ttgtccttgc ttaactactt agaaaacttg ttgctcatgg tgggtagaac
    14881 taaaaggggt gatgctatga atactagagc gttgaaacag cttgctttca acgaaaaaaa
    14941 tgattaatag gtgtggtgat tttaacttag gaatgggcgc gaaggtcatt accacaccga
    15001 catatcgtgg ctcattttct tcgcctaact ggtataaaga aggagtaacg agagatgaag
    15061 catgaaaaaa cgataatttt aaaatcaaaa ataatttatt gttttgcgac tttagtaatg
    15121 atgttatcta cgcttataat gcctttttca gcaataagag ctgaagcaga tgtcacaaaa
    15181 ccgacaagtg caaaatttat agaaactggc gtaaaaacag acggttatat tagggttaat
    15241 atgccgaatc atccaaatga atggatgatt tcaagtcaat ttaaagattc tcatggaaat
    15301 attggatatt gtatggattc agaattgcca tccccaacag gaagtggagc cggaagcttg
    15361 aagtacaagg gagctggcag tgatgagttc tatcgtatgt ttaaaggtgg ttttccatca
    15421 aaaacagcaa aggaactggg tgcaggaaat gatacagaag catggtatgc aacacaatta
    15481 gtttcatggg ttttagccgg aaactttaaa gtttcacaga ttgtatggtc acatccaaac
    15541 cataccgccg cagaaacagc tcgtgtaaaa aaagcatttg aaaaaattta tgactatgct
    15601 aagaatggaa aagatacgcc caacactgag ttttctatca cagcttctaa gacagctgac
    15661 gaaggaaaat atcacacttt cacatataaa acagcatcaa ataagactgg taatgcgaag
    15721 ctcactttta catcagcaaa accagctggt atgaagattt atgatgcaga tggtaaagaa
    15781 attactaaca acactgtgaa attaaattca agttttacta ttaaagtacc tgtgactaca
    15841 ccaagtggta ctttgtcatt taaaggtact gctaatgtta gcacaaccaa tccttttact
    15901 tttgatggac gaggtgtgta tcaagatgcc gtagttatga tcactacttc agaaacaaag
    15961 gactctaaat ctttgagtgc taaatggaca agagctgttg gtcaggtaac agttaagaaa
    16021 gttgatcaag atggaaatgc tttaaaagga gcggagttta ctctaactga caataacaat
    16081 gctaaatctg ttaagacaac cggagatgat gggttagcta cgtttgattt gcaacaaggc
    16141 ttaacataca gcttagaaga aacaaaagtt cctgaaggtt atcaaggttc atttaaaaag
    16201 gatggtatta ctgttaatac cgatggacaa gaatttagtt acactgctac gaacacaatt
    16261 aaaaaaggta aagtaaaagt taaaaaggtt gaccaagatg gaaaaccatt agctaatgct
    16321 gaatttacct tgacggatga ttcatcccaa acacaagcag aaaaaacaga tgaaaacgga
    16381 cttgcaagct tcgatattgt agcaaacaag acctacagcc ttgaagagac cggagtacca
    16441 actggttata caggcgtatt caagcaagaa ggaattaccg ttaaagatga tggacaaact
    16501 tttgaatata cagctacaaa cactttgaaa aaaggtttag taaaagttca taaagtcgat
    16561 caagatggaa aacctttggc aaatgcagag ttcactttaa ccgatgaaaa aggtgcaaca
    16621 caagtagaaa aaacagatga aaatggactt gcaagcttca atattgtagc aaacaagacg
    16681 tatagcctag aagagaccgg agtaccagta ggttacacag gtgcatttaa gcaagagggt
    16741 atcaccgtta aagacgatgg gcaaactttt gaatatacag ctacaaataa tttgaaaaaa
    16801 ggtgtagtaa aagttcataa agtcgatcaa gatggaaaac ctttagcaga tgcagaattc
    16861 accttaacgg atgaaaaagg tgtaaaagaa gttaaaaaga cggatgcaac tggtctggct
    16921 acgttcaaca ttattgcgaa caaaacttat aacttagaag aaacaaaagt accaacaggt
    16981 tacacaggcg cattcaaaca agaaggaatt accgtcaaag atgatggaca agtctttgaa
    17041 tatactgcta aaaacacttt gaaaaaaggt gtgatcaaag ttcataaagt ggatgatcaa
    17101 gggaaagcat tagcaaacgc agaattcact ttgacagacg acaaaggtgt aaaagttgta
    17161 caaaaaacgg acagcaatgg cttggcaaca tttaatattg ttgccaacaa aacgtacaaa
    17221 atcgaagaaa cacaaaaccc taatggttat acagggaaat ggtctaaaga aggcatcacc
    17281 gttgctgacg atggacaaac ctttgaatat acagtaatta atcaccttgt acctgaaaca
    17341 gtaagaacag gcggaatcgg tacatcagcc ttccttcttg tatttctaat tgcaggattg
    17401 agtatggtgc tactgtatta tcgagaacag cacaaagcaa aataaaaaag tgttaatgga
    17461 aaagaagtaa atatgaaaaa agaaggctga cgtatgaaat caaaaaaaat tttttcaaat
    17521 ttaatgctat ttggtacttt gctaggagtg ggattgggcg caagctcaat ctcttctagc
    17581 cttggactag gggggcaagt agcatatgca caacaaaact ataattatca aggaactgga
    17641 acgattcata tccataaagt aacaaatact aatggggatg ggaaccctgt ctcagatatt
    17701 gataacaaag ggaaagaaat agctttacca aatggtgtaa aacctcttga aggcgttgag
    17761 ttctcttatg tgaaacttac taaagatgaa gctaaatcct tgggatggac ggatagtgat
    17821 actacaaaag gtcaacatat tgatgatgct aaagcacgat tattactaaa caaaaaatac
    17881 agtgaagtaa gtagaatgaa gactgattca caagggaata tagacatacc tatacaagta
    17941 aatacagacg atttaacaga taacttgtat ttgattgttg aaacaggaac agtcaaaggt
    18001 gtagttgaag aagcgtatcc tatgattgtt aacgtacctg aactaaacgg atcagatgat
    18061 caatacttta attatgatgt acatgtctat cctaaaaact atttccaatt aaactcagca
    18121 gagcttgata aaaaagacga agatggaaag gctcttgccg gaactgtttt tgaattgcga
    18181 aaagatgatg gatctgatca ggttgttgga acttataaaa cagacagcac aggtaaatta
    18241 actgtagatg gtttggaatt aggtgactat tatttcctag aaaccgattt gggaacagat
    18301 gctaataaaa caacctattt actagatggt aaaaaattca aatttagcgt taaacgtggg
    18361 gagactgcta aagtagttct tgatgttacc aactacaaac gacctgtaat tactaaggta
    18421 attgataaag aaaccgttga tactggcgaa gatgttcaat atacattgaa accatcaatt
    18481 cctggtaata ttggtaatta cgaaaaatat gttgtcaaag atgttctagg tgcagagtta
    18541 acttatgatt catcagaagt gatcgaagga atgactttag atactgatta cagtatcgaa
    18601 cgtgacggac aaacgacaaa ctatgtcttt actgaatcag gtatggataa gcttcagaaa
    18661 caatttgatg caggggatcg cttctttaca attttgatga acgctcatac taatagtaaa
    18721 gctaaaatgg atacaccact taagaatgat gtttcaacga tctacaacaa tggatatgaa
    18781 cccgaagacg aaacaccagt tgatcacgct tatacaatca ttggtgatca ccaattcatt
    18841 aaaacagatg gagatacaag caaagcattg agtggagcaa aatttgtagt gaagaacaaa
    18901 attgatccga ataaagttac ttacctaaaa caagatccaa caacgaaatc tgttacttgg
    18961 attgcagata aatctaaagc tactgaattc gtttccggat cagatggtaa gttccaaatt
    19021 gaaggcttgc aatataccta tgatgtagat tttgataaac aaggtaatcc aacaatcaca
    19081 gataaaaaaa tcaatgatta tgctcttgaa gaagttgttg ctccttcagg atatacacca
    19141 actagaaatg atgttccatt tgtggtatcg aatgatgatg cttctagcga agtaacagac
    19201 atcaagaacc ttaaaacacc tgaaacagtt cgtacaggtg gaattggaac agtagtattt
    19261 ctagtggttg caggtgtggc aggaacaggg ctatatgttg tctacaaacg agaacaacac
    19321 aaagcttaat gaaataaaat tccctagagt gtttttggct ctagggtttc tttttaaaaa
    19381 gtgtgtgaaa agtaggtatg agcatgaaaa agaagaatat caagttgatc atcttaaaaa
    19441 ttgggatgtt gctatgttta ggagtaggtc tatatcctgt aattactcag gcttatacct
    19501 actaccaaac tcaacaaaca ctaaactcct ataaggaaaa atatgatgaa gcttctgaaa
    19561 aggagaatga agaagtcttc aagagatatt cagaagttaa taggaaacga aaagacacag
    19621 aacaaacctc agtcacgatt cctgaagata ataacaatat tccgtcaaat ggaaatcttc
    19681 agaaggataa attaggtgaa ttagtgggtg aaattcttat accaaagatt aatgtggatt
    19741 tgccaattta tgatggtgta aacgatttcc aactatcagc aggagcagga atattaaccg
    19801 gaactgatta tccaactggt gggattggaa accattctgt tatatcagct cattcaggca
    19861 ttcctaataa aaaatatttt acagatttag agttgctcaa acttggtgat aaatttttta
    19921 ttgatatttc agggaaaaaa cttgcttatc aagtagatcg gataaaaaca attctaccaa
    19981 ccgaatttga ggatttgctt cctgtggcag gaaaagatta tgtaacactt atgacatgta
    20041 cacctgttgg agataattct cataggttac tcgttagagg ggttagcata ccttaccaaa
    20101 aaagtattgt tgagaaagaa aagaagaaag aagatttaaa ggtaaaggcg cagatgaact
    20161 ggtatcctat cgtagttgta ggggttttat taataatagc tgtgatagtc attattaaaa
    20221 aaatagtagc aaagagacga ggaatgaaaa atgaagaata aaatactact ttttttgact
    20281 cttatttgca ctttggtttt aacaatttat cctgcaaatc agctctatca tcaattcaaa
    20341 acaaaagaga atgtggcgga aatccaagag aaaattgaga aaaaacaaac tccttcaaaa
    20401 gaggaagtgg caaaaaaagt cgaacaaata aaatcgaaca gcggtaacca aggattagac
    20461 aatactcaga aaacagataa aggagtagac aatactcagg aaacagacgg tggatcattt
    20521 gatattcgtg aagctgaagg aaaggtcaat ccatacacag gagatgtttt ttcaaaaaat
    20581 caaacgaaag attttgaacc atctacctat tcaggagcgg ttggttatgt ctatattcca
    20641 aaaataaatg tgctagagct tttgtttcta ggcgcttcac aggagcattt atatagaggt
    20701 gtggcacaaa tgagtgctac tagtctacct ttatcaggta aaggtcatca aacagtaata
    20761 gcaggtcatc gtggcggtta tacgtcacca caatttcttt atgttgatca attagtagcc
    20821 ggagaccaca tttatataga ttatcttggt gaaaaagcag tttatacggt tttccgaaca
    20881 gacgttatta gaaattacgg tcagaattca acactgactg atattcctga tttagatatg
    20941 ttaacacttt atacttgtca tccatatcct cagaactacg atcgtttatt agttagaagt
    21001 ctaagagatg aaaaagcaaa atacatcacg ccacaagtaa cagttggcaa taccgcatac
    21061 gctgatgcca ttgatagcga gtccgtttca gataagacag aaactgttac atcttctaat
    21121 gatttatttg aagatgttga tcgtgccaac aaggaattag atggaaataa tgatcttaat
    21181 attccggaac aaggtagcgt agagatgcaa gacagaacgt ttgctgaaaa ggcaagttca
    21241 atatttacag gaattaccaa taaacatcag aaaatgcttt tagtcatttg gactgtaata
    21301 ggagcattag caagtctaaa ggttcttatt cttttaatca aagagtttcg aaaagcataa
    21361 tgaagattat aaaaattgat agagtacagt aaaaagggat tgatactatt attgatctct
    21421 tttttatttt gaatagagct agattcactt ttaaataaaa tcaaaactga tcttaattct
    21481 aaagaaaaag tcaagaaaaa aatacaataa atttttttat cagaatattt atcagaatat
    21541 tattagaaaa gataaactca aaagcttaat ttaatagggt tattggttgt atttagaaat
    21601 aatgtatgga aaagctataa agcaatagat aagatgtaga aaatcttatt tgtgaatgaa
    21661 aaacaagtca tcgtaaaata ttaataggag gtgtagtaat ggtgggagta tcaaaaacag
    21721 ctttagactc attagctaaa ctatttagta gcaggtttga tggtgcagaa tttgttgaat
    21781 atctaagcca aaacgaaagt ggaaaaactc tgatcgaaac aatgaaaaaa gactatttga
    21841 atgaaaatga ctttccgaca tggacgaata ttgaagatgc tacatgggat gtagtatgta
    21901 cgatatattc tccttgggta acgattgctg attttgtttt agataaaatt ggaggggata
    21961 cataccctga tgccaaatct cttgctacaa gtgactttaa aacgttctat ggttatctaa
    22021 taggtctaat aggcaatgga atagatttga aagttacgcc aaaacaaaca cctgaagaaa
    22081 ttgaaaaaga aaaaggagag gttcaaatgg cttatgcaaa tgacagagaa aaagtaaaat
    22141 tattggaagg taaattatct gaagaagaac ttggaaaaat ggtgcaagaa atcaatgaag
    22201 acagcaacta ttttcctgaa ttgaaggtat atcaaaatga cgaagatttc tttaatgaaa
    22261 tgtttagtaa tagtccatgg gaagcagtaa gtaaaacaaa tttaggagaa tggaactttc
    22321 aagatgatct agttgcattt agcaatgatg ggtatttacg atcatattca gaaagtgagt
    22381 atagagctga attaaaaacg tatgaaacgg atattctgat gagctattta aatctattag
    22441 agagtggtca gggagagtta agagataaag ttgaagaact attaaaagaa gagctatagg
    22501 gattatttca acataaacac aagcagaaaa ctaccaaaca aaacgtacca tgcaaaaagt
    22561 cggttaaacc ggctttttgc tctattatga gaggagatca aaccatgagt gcaacaaccg
    22621 atatggcttt agaagcagta ataaaagata atacaggaaa tgtcgaaaat gtagaagact
    22681 ttagcgatat tgcaatcaat ctttcagcat ggatttcagc tgtagaagaa gaaaatatcg
    22741 aatttgagat caagaatatg gatgacttaa aagcaaaatt tccttttatt gcatcgaaac
    22801 taagtcaagt tgccgaggat aaatcgtgga atgaattagt tagtttttcc gaaaaaattt
    22861 atgatattac gcaagaagat gagtgtgttt catgggaaat gaataatcaa tacaagaaaa
    22921 ttgacgcttt cgtcaaatca cgtatagaag gaacagcttt tgagtttgaa ggtatagata
    22981 ccgcagataa ttggttaaat aaagaatcct ttattaaaag tatagcggat gatcttgaaa
    23041 aacaatggtc taaggaagac tatgcagagt acctaaaaac agaaagagat acagaagtga
    23101 aagaaaaact cactgaggta tgtttggatg aacatattga tcccaatatc gtaaaacaag
    23161 aagactatga agtggttatt gataaagttc ctactgattt tgaggaagtt gtaaagtata
    23221 tagttgaaga agcattatcg caatactctt cagatgagga agtggacgaa gaaactgttc
    23281 gtaccagagt ttggcaactg gtttttgatg acaaagatta taaatatttg agtgatcaaa
    23341 actcggttaa ttggagtgta cgattattaa ttgatcaaaa tgatattgaa taaaatagag
    23401 ctgaaaagct ctattcagat tgtagacaaa aaggagttgg taattaagcc actccttttt
    23461 gttagtcttt gcataatttt gaaataaaaa gccataggct tttttgtttt ccatagccat
    23521 gtggctagtt tttttaaatt catggcagca aacgtaagca tcgtgtgcgt ggcgactttt
    23581 tcaagacctc gatatttcgt ccaacgcata ccatgctttt cttttgcatc tgcaaatatt
    23641 cgttcaatgg tttgttttct ctttttgtaa atttctctat tcaacgccgt atggcgttgg
    23701 tgttcaagtt catccataag atcagcccaa atatgtcgag tcactatttt ttgatgtttt
    23761 gtactcaaag tacaattttc aagtaatgga caactcacac agaattttgg atttgattta
    23821 taggttcgat aaccatcacg agtgatagtt gaaaataaca acggttgatt attgggacat
    23881 aaatagcagt caaaataggc atcataaaca aagtcttttt tacgaaacat tcctttcact
    23941 ccatgaggtg cagtatatgg aagaatcggg tagagtttca agtgtgacag aaaatgaaca
    24001 aatttaggcg tcttatatcc tgcatcagca accacacgct ttatatttgg aaaagctctt
    24061 ttcgactgtt taaccagatc gattgcgact tggctgtcat gcacatttcc tggtgtgatt
    24121 aatgtagata agataaaacc gttatcttca caggaagtat gtgcagaata agcaaattgt
    24181 ttttctcgtt cacctttaac atagtaacca ctttctggat ctgaatgact tattttttga
    24241 agactcaact cactttctgt gtcccatgta aaaggacgtt ttcctacagc aatacgttct
    24301 ttatttattt catcttctaa ttcatcttga taagcttttg cttgaccgta ggtcatctct
    24361 ttcgtgaact tatgtttatt ggcatttgct ttgatatgag tagaatcaat ataaaggttg
    24421 tcttccgtaa cgaagccagc ttttacagct tgttctagaa tatgagagaa aatatcttca
    24481 aataaagttg tttctctaaa tcttcgaaca tagtttttac caaaagtaga gaagtgtggg
    24541 ataggatcct cgaatgaata acctaaaaac caacggtaag caacatttgt ttcaacgtct
    24601 ttaattgtct gtctcatcga acggatacca aataaatatt ggataaatac taatttaatt
    24661 aagaccactg gatcaatact gggacgacca taggttgaat acgtagattc tacaatggga
    24721 taaatgaaat caaactgaat cgcagcatca atttttcgaa ctaagtgatc tttaggtaca
    24781 agatcatcaa ttgttaacat agcaaattga tttctacctt caatcgattg ttttctcatc
    24841 attagaatca ctcccagaat agtttataca attagtataa aacaaaaaac tgcaaacaac
    24901 actccaaatt taggagtttg tctacagtct gaatagagct gaaaagctct attttttttg
    24961 ataaaaaaac tagctatttt attaaaaata atttggttca aaatttattt ttttaacttg
    25021 ataatttttt gccatccttt tttaaattgg ctatatatca aggtttatag tgggaataaa
    25081 taaaaataca tttgacaaaa tttacaatat agtttattat atatttatct tattatgata
    25141 acacaataaa aggaatggtg gtatgaaaaa gaagaagttt agccgatcgt tgttaggaat
    25201 tttggtttta gttgcggttg gtcttagtgg caagggttac tttcagaata acagtactca
    25261 ggaacatgat tttcagatca aaagtagtgt tcaggtaggt aataaagcag acagtgaatc
    25321 aaaagaattt ttagggatac gttatgatcc aaacaaatat ccaaataata tcgtaaacat
    25381 taatgatggg aaatatacac tgacaaaaga agaccatgaa gcattatcag aaaaaggcag
    25441 tcaaaccttt tgggtaaatt atgcagattt agatcaactt ggaagagcag gagatgttga
    25501 agcgttgatc acctatgatg ctgtaaattc tcactcatct aaaaatgtgg aacgtccatc
    25561 tttcaaaagt tctgtccata ttgcaggaga atacaaggat ggagtatttg atcaagagag
    25621 agatacttgg gtcggcaaag attcaaacaa tgaaatcact cagctagaag gctataaagg
    25681 ttatctctat aacaaaagtc attcattagc atggtcgcta ggaggagata tggaggtaca
    25741 caatttaaca cttggaacga gagcgcaaaa tgttgggaaa aatgatcaga atggagggat
    25801 ggcttactca gaaacgattg tacgtgatgc aatctataaa aataagaatg aaaaagtatt
    25861 gtataaagtt gatccaattt ataaagggaa tgaattagtt cctcgtggtt ctcatgtcga
    25921 agctttctca gttaacgata atggaaaaac ggtaaacctt aatgtttatg tatttaacaa
    25981 tcaaaaagga atcaacatca actatcaaaa tggtacttgg gtaagagatt agaaattgag
    26041 aaggtgaaga attggaaaca ataagcatca atggattaga taaatcagtt gcaaatcgaa
    26101 taaaaaaagg aaatggctac tatcttctga agaagggtaa atattcagtt gctagagagt
    26161 tagaaacaat gagtatcgtg tatgtagcta agaatcattt tgacgtagaa caggctattt
    26221 ttgatccaga ttctgaaata gggaaatgtg ttgaattatc agagaaaact gttagtacaa
    26281 aaggggcgat gatcattgag agagaaatgt tagacgaaat cagagtaatc attcctaaag
    26341 atacgcagat gtgtgaggac agcataagtg acgatgaacc aaaatcagaa agaaaataag
    26401 gagatattca gatgagcgaa aaatccattg aattaaagga atataagcga agcgatggag
    26461 aaaaatatta tcctgtagcc agtttttcta aatcagtata tctggttgga cgtgcattgg
    26521 tagttggtgc aattggcata tatattttgc attgggtaac aaaggttgta caactgcttg
    26581 tagatacctt agtaagtatt cttgtctcgt taaatgatgt taacggaaca gatgatttag
    26641 gattaaaaga gatgtttaaa gagttactca atgcgttttt tcccaattat ttaagttatt
    26701 catataatgt acaaagcttt tttgcaaagc tacacttggt agacatctct attttagtat
    26761 tagaagcagg aacggtattc tttgttggat atttggttac tttgatgttc aggcatcact
    26821 atggagaaca aagaccattt tttgatgata tggaaagtag aaggttgaaa agagaagctc
    26881 tagaagctat ggatgtgaag tatgatccaa acaagattat aggagatgaa acgaacaaca
    26941 aaaaaagaaa acgaaacaaa acgcaattag aatccgatgt gctatcaacg cttaaaaata
    27001 tcaaaatttc tgttcataca agacgtgatc taagtgtcaa tgaagatatt cgagaatata
    27061 tcgtaaaaat cccgcaacca aaagggaaga aagttagaga aacagtttta cgacaaattc
    27121 aagatttagg gtcgatcctg acaagagcaa caagcggacg agccaaattt ggtgaaaaag
    27181 aagatgaagt ttcaggcgat tatttcattt tccgagcatc agtaaatatt gaaagagaac
    27241 gtaaggaaag agtaagtacc aaaaacaaag aaacggaaag agcaacatct tcaatcgcag
    27301 tttcaaattc acaattttct tttccaatca atctctttgc cgataattcc aaaaatatcc
    27361 aaaaccaaac cgaaaaagct agaaaatatg ccgaaactca aaagcaatct ttagaacttt
    27421 atctatcttc tgctgacgta cctgcaagtc taacagatat gcacgttggg aatacatcta
    27481 ttgaatattt gtttacttta tctcgtacca gaaaaattca actaagctca atgaaagaag
    27541 aaattgaaac ttacttgcat atatcaggtg taatcgtgcg gatcaacgca gggcgtattc
    27601 aaattacttt accattagga gaaaatgatc gtattccaat tgatgtacca tcaatgatca
    27661 atagcgtgtt ttagaagaca tcacaaatag aaacagaaaa tacaaactac cagttcacaa
    27721 acagaaaagt accgagaaaa gtgaggaata gaaatggcta tgaaattatt agagaaagtc
    27781 aaaaagagag ccgaaaaagc tgaatctatt ttgctagata aagaacctaa tataaagctt
    27841 aatggaaaat tcagtgtcaa tatgttgaac acaaaggcta aagacccaac agatgctatt
    27901 tttggaatta agcctgatgg cacaattgct catttttgca tcagcgaaat gccacacatg
    27961 ttggttgcag gaacgacagg atcagggaaa tcagtattac tgaatgaaat tcttgttaca
    28021 gtaatgtgtc actcaacgcc tgatgaatta aaaataggaa ttgtagaccc aaaaagggtt
    28081 gaatttggaa gatacaaaaa attgccgttc atgttggctg atccaattac agatatggat
    28141 gaagcttatg atttttttga atatcttgtg atcttgatgc atgaacgtta caaactgatg
    28201 gaaaaagcag ggttacaaaa catcacgcta tataacgaat atgccgaaaa aaatggatta
    28261 gatagatttc cctatgtgat cttattagtt gatgaatatt cacagttggt tggaacacat
    28321 aaagaagtag aaggtttgat tgttcaatta ggacaaatgg caagggcagc aggtattcat
    28381 gttatcttag caacacaatc tcctcgatca acagttgtca ctggtattat caaagccaat
    28441 tttccgtcac gtgtttgcct tatggtagca agtgatttag aaagtaggat tgtattagat
    28501 gaaggcggtg gagaaagtct aagtccaaag ggagatatgc ttattaagct tgttgatgga
    28561 agtatggtta gagcgcaggg agcttacatc agtaacaaag aaattgaaac aatcttcaat
    28621 caccttagaa atactatgcc agaaccagaa tatgttgatt accgagcaat cgtagctgaa
    28681 actcgtggtg agggcggtga agacgaggat tttggtggaa ttggtaaagc tcctgtaaga
    28741 aaatctgcta aaagaaattt gaacacacct ttagcaaatc catcatctaa agagccatca
    28801 attgaaaaga agagtgcgtt tgctattaag cttgaaaaga acaaagaaga aaaagtcgag
    28861 cagggagcta aaacactaga aaaactgcaa gcagaaaaac tagaaaaagt tttaagggca
    28921 ttaggaaaag ctgatcctga accgcaaacc tcaaacaaca cgaataataa acagccgatt
    28981 gcatctaaaa ccaaacctaa agctaatgat ccaaaaggct cagaaaacgt agtgatcaca
    29041 actgataaat ctgaaaagaa acaaataaat ggaagtactt cacctatcat gcaaaaaatg
    29101 ttaaaagcaa aaaaacaggt gcataaatga tcatcgtcag ttctttttta agatggctta
    29161 ctccatataa atatacagat gaagtagttg tgaaacgagc gaagaaaaga gataaaaaag
    29221 cggtactaac tcctaaacag atgcttgatc atggcatttt aggggtgaag gttttagaag
    29281 tgaataaacc gtttgaatca aatagtgcaa gagaaaagtt gcttggagct gaagccgatg
    29341 tcgcatattt ttaccatgac aaaagcaagc atcaaatagc tattaaattc aatccaaaat
    29401 cggcatggcg gtatcaagca agagatgact tgaaacgtag gaaacttaga ccaatgctct
    29461 atccagaagg aaaagaagca tttgatagaa cccacatcgt tcccattggt tttcatggta
    29521 cagaatcaga taaccgccta ttagtaggtt ggaacagcaa tcaaaataga gttcagatca
    29581 ataaatttga gaagaaagta aggaaattca acgatcgaaa aacgatccta tggtttgcag
    29641 atatttgtaa acagccggat ggaacagcaa agtgggaagc ggtgatattt gacgaaaatg
    29701 gtaaaaaagt aatgtctgaa acatggcatg ataaagctaa atttgtttgg cagtagcagt
    29761 agaggtgaaa aagattgcta gaactttttg aagcaaatag aacaggcttt aatgggattg
    29821 gcttagatcc aatcatcaag aaccgtagga actacgggga tagcttggta aataagagac
    29881 accgctgtta gtaaagaaat acgctatcaa gtatgctcta ttcccaagaa gctcccactt
    29941 caagcgttaa gaaccgtcag gtttagctaa gtggtgagta gttcactaga accttggtca
    30001 caggcagaaa ttgataaagc agtaaaattg aaccgattat caaaatttaa cgtattagga
    30061 aatgcctttt aaaaatcgca atacacaaac agaaaaatac caaaaaatta gcaatgaacg
    30121 taggtaagaa catgacaata aataataata accctaaaaa atataatgct cttgtccaat
    30181 gctatatcga aaacaaaatt acaatgcaag aagtcgctga tgaattaggc aaatcaaaga
    30241 gcctagtatc acacgatttt aagcacaatg tttttccgaa cccgattgag ctgaggaaaa
    30301 aatttcaaaa gagagtttat caagaaatag gtaagtggat tgatgaaggg aatgcaattg
    30361 accctttaat tgaaaaatat ccttttttaa aaagcaaaaa taaaattcaa aggttaattc
    30421 gtcaaggcga tattcaagct aaagaacctg ttttgacaac caatgatttg gctaaaataa
    30481 atcttcataa acaaattatt gaagactttg aaaaaaatct ttcaacaact gaaattttaa
    30541 aaaaatacaa tattccgaga ggaaagctaa catcgactct ttttagagaa tatggagaat
    30601 cggcagttac taaagcaaag gaagtagcga atgagagaaa aaaacaaaaa tagtagtcga
    30661 tacctagtag cgactgtagt ttttgtttgt gtattgattt tcctgtttga ttttttgcag
    30721 attggaaaaa gcataattgg aaatacattg agtgcaaagg aaatggttgc tttaggtggt
    30781 ttgtatgaag gacacttgtt cccgaatata ttcatttcta tcgtttctca tattaacttg
    30841 taccatttaa tttctaattt attgttctta gtagttcttg aagaagcact gaatgatcag
    30901 tatgagtggt taacattatt gatcgtttta atcatatcag gatttctagg aagcttagtt
    30961 ccttttctgc tacacagcaa catcgtaagt atggggctta gtggaggtat ttttggatgg
    31021 attgctttat ttgcgattgc atacatccgt tttgatagca agaaacattt attactaagt
    31081 gtttttgtat tattgataat cggcatttta ttggtatcta cttttgaatc aggcgaggca
    31141 aatgtcttgt cacatgtaat cggatttgtc tgtggaatga tcttgggatt tattctaaag
    31201 aacgtttcat tgatcaaaca aaagaattaa aagggagtgc taaaaatgcc aaaaagaaaa
    31261 gaaaagaaaa ttccagtgtt tttgtctgtc tcagaaatgt tatcacttca aatactgtta
    31321 agaaaaaaga ttgaaacaat agacgaagaa gttagaaata aaagggctat gtacgaacaa
    31381 cgtgaagcgc taagagaacg aatccactat tttgatgata tacacactaa aatctatgaa
    31441 gcacgtacaa atcacgaaga cgaaagtaaa ttaggattag ctcaacaacg gatacttgaa
    31501 tggcttaata cgaatactga tcaagaaccg ttaagagtga ttagtaatct ttttgaattt
    31561 ggaacgaagc attggtttaa tgctgtagag aaggatgctg acttacaaga agcgtttgat
    31621 acgctaagta aggatagcaa atccatgcga gatttattga ttacttatct aaatgagcat
    31681 gagtttgaac aaacgaaaac caaaaagaaa aataaagaat agaaagttgt gatgaatcat
    31741 gctattaacc ctgttaggtt atttatgttt aattcttgct ttttttgggg caatcgctat
    31801 aattattggt caatttcaaa caaataatcc gattatgcgt aacataggca ttggaattgt
    31861 gattgtaacc tttattgtgt ttaatgccac taagattttt ggaagtaacg ataaacaatt
    31921 tggtatatcg ggagttaata atagttatgc tccagattct ttgggaaggg tagtaataga
    31981 tggaacattt gaaaatgtaa cgagttataa aaatgtttcg ctgacagtga aggaagatgg
    32041 caagaaagca tcagacgacg ttctcgctac tattaagccg tctcaatcac aatttgaagt
    32101 gttttataca gttaaagaga atagccctgt acacaagctg acattggttt ttaacgttga
    32161 tggagaagaa tactataaag atgtaaaaat aaataaaaca tcaacgaaaa agattatcga
    32221 atcagcgaaa aaagaagtag ctacagaaga aagtacaact gaatcaagtt ctactgtcga
    32281 agcggaacta ccagataaaa ttgattttga tcctgaaaaa gtcaaatcgt ttgaatctgt
    32341 ttctggttct atggctgatc ggtttaacac tgaagtcttc aaagctatca aaactgttaa
    32401 attggatact gaaaagcaaa tgattaatgt taccttattc aattcagttg aatctatgga
    32461 tcaggataaa aaagttacgg ttgcaagaga actaggaaaa agagtaattg gtttgtatcg
    32521 tggtactgct aaaccagatt cagacggtgc agatttgcca gttcatgtag tttatgaaga
    32581 cggtaaagtt tttggagatt ctacagcaaa cgaagcatta acgattaaat tggctaaata
    32641 gccagaaagt tataataaac aaatggtgtc acaccaataa tatataggtg tgacaccttg
    32701 gagatgatag ctgatggtag taaataaaga aaaagttaga aagtatgtga ctttaaaaat
    32761 agcttctgtt aaatatttag aaaagcgagc taaagaagaa gaaagagcaa gaggtaagaa
    32821 agtaacagtt tcagagttgt tagaagaatt gatcgagaat gatcaaacaa taagacgtgc
    32881 atttactaat aggtctatca gataacaata taattaataa aaaagaaaga gtgatttggt
    32941 cttagactaa atcactcttt ttatataaag tttctttaca ctcattccga ataatgttaa
    33001 aattctttat atgatatata gttccttgtc agaggaagag ataaccagca atattggagg
    33061 gataataagt ggaaaacaat aatgatatta gacattttag cattggggaa agagttacaa
    33121 cagtaagcga attatcaaag gattatagag ataaagaggg aacgattatt tctcttaata
    33181 agaatcgaag aggcgtttgg caatatgttg ttgatttagg tgatggcgtt acagttgagt
    33241 gtaaagatag tcaactgatc agaaataatg gcagtcattc cattgaaaaa gcaattcttg
    33301 tatacccaaa agtatcaagt aagatcatga atgactggtt gcttggaaaa tttggtgagt
    33361 acaataaaaa agaaatcgca gaagtgatcg gcaaatctta tccaacagta ttagggtatc
    33421 taaaaaagat aacgagtaaa gaagcaaaaa ttgaggatgt tttaacagta agagagcttc
    33481 aatcattaat cgagtatcgg aataaacaaa taacaaatcc tgagtacctt agaaaagaag
    33541 atggtctatt gaaacaattg gaacaagtaa ataaaatccg gaagatgcaa aaggtagctc
    33601 ctttaagcct tgataccttt aaaaaaatct atttgaaaga gatcaaaaaa gactaatgtg
    33661 gactgtaact ttaccgttcc aacctgtatc tgcaccaaga ccaagtgcaa gaaggaatgc
    33721 tgctgatgaa actaatgacg tagcagagaa aaggatttca acctactatg ataaaaagta
    33781 tcttgattat ttgaaaaaaa taaagagctt tatcgaagat caagatttat tagatgatga
    33841 attttactcg attgtaaatg atcctatggg cgcaattatg gaagtggact tttactacca
    33901 gataccaaaa agctataaaa aagtctataa cattatgaag acaacagcgc cagatttaga
    33961 taatttagta aaaagtgcta tggatggtat ttttaacatc tcagctatac gagatagcca
    34021 tatcacaggc ttaattgctt ttaaatataa tgtggcgaac gaaggaaaaa cagttgtgag
    34081 gatcaaacga tattcagaat ttgagtggga tacttctgaa ggattgaacg gagatatatg
    34141 ggaagctaca tttgatttta aaccagtagc aacgccaaga ccaaagtcta aatttagagg
    34201 aaatgggatt atcacttact atccaaaaga gtacaacgac tatttggaaa atatcaagaa
    34261 tacgcttaaa gagaaagatt tggtaaatga tcaactgaaa aaggtaatga atgctcctat
    34321 gggggttata gctcagatag attattttta ccaagtgaga aaagataaga aaaagcttga
    34381 ttcactgatg cgtacttcac agccggatat tgataattta gtcaaaggaa cattggacgg
    34441 aatttttaac aaggaaatag gcatcaaaga tagcagggtt gtagggttaa ttgcttttaa
    34501 atacaatact tttgaaaagt cgaaaacaaa cgtgagacta caggagatgg gctgatgaat
    34561 aataatgaaa aaattcttca tgtacttgat agctttgaaa taattcaaga agaactaaaa
    34621 aaatatcggg atgttttgga acaaagatat gattttgtca atcagcaaaa gagtaatcac
    34681 atggatttca ttctcaatat gaatgacttg aagaagaaat tagttgaacg aaaagaacaa
    34741 gaaaagttga tcaaagctta ctttgaactc ggtgaaaaag aagttaaaaa tgcaatggaa
    34801 ctgaatgaag agcgcagggt tttagatcag ctgttagaac aattattggt gatgtttcaa
    34861 aaaggacgaa tagatgagga tttaattgaa gaaggattga gaaaatatcc ttcaaactca
    34921 ggtatcggaa tagtgctgaa agcgattgat gaagaagaaa ttgaagcttt cataccgcca
    34981 gaggattttg aatcggcaat ggaatatata aaatattata gccaagggat cactgctttt
    35041 agagagtttg atcctgaaga tgttattcat gacttgaaca acctaaaaga atggtgtgaa
    35101 agttatggag tcgatgattc cggattggac tacttgatca gtattatgga aatcgaagaa
    35161 gagatgccgg ataagcctga tccaacagat attttagaat tgatccatga agctagaaat
    35221 ccaattgcct atatttctag aggatatact gtattggaat actataagcc ttatatatca
    35281 gcgatgaacc atttaagacg tgtattaagg gaaaaacgtg aataccgctc agtgttgaat
    35341 gcaacgaata gattagaaaa agctgtttca gagctagatg cttattatcg tgaacattac
    35401 ctgcaagcag gtggtatgcc aagaaatacg aaagcaaata tcagtaggta tataaaaaaa
    35461 gctgagtagg cggagttagc ccataaaatg gcaaaaggta acctgaaagg ggcattttga
    35521 atgaaaaggg atgtttttga attgtacgta ttagaacgtc tagaagacgg catgatggca
    35581 caagagataa ttgatgaaat tgatgatatg atcagcagat ttggtcaatt ggagttgaat
    35641 gatggaaaca aaaattcggt agtgctaaaa caattttggt tgaacaattt ttcgtataag
    35701 gattttatca aagaaaaggc aaatacattg tactgactaa attcacgagg agcagtgatg
    35761 agagcttatt gctaagagca gttaggctct tttttgtttg tgtaaaatta tttgttttat
    35821 aatacacatt tatacacaaa aaatattgac agatagtaca caaatgtggt aggatatatt
    35881 tgtaagcaag ttagattaac aagttaaagg aagagcagtt atgaaaaaag aagaactaat
    35941 agatatattt caaattgttg aacgagcaaa taatatggga attatgtttt ttgatcgtat
    36001 ttctttaaa
//
LOCUS       DACGLI010000029        35462 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.030, whole genome shotgun sequence.
ACCESSION   DACGLI010000029 DACGLI010000000
VERSION     DACGLI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.030"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            29..1297
                     /locus_tag="IXT22_001523"
     CDS             29..1297
                     /locus_tag="IXT22_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAQ4862894.1"
                     /translation="MENRLPDPLKVIIYMIKWLLITAILGIFMGSLSAFFLTSLTDVT
                     AIRLEHPWLLFLLPISGGLFAYLYTTYGGNSSRGNNLVIDQGNGGNEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALAENFARWLKLNKIEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEALFPSFFAALFANFVTESFNVKHTHYQMGAIPAWDPS
                     LFFKLLLAGIAFGIIGWLFSRSIVWLKAWYAKRIPHPVLRNFIGGAVVVLVVVILQTQ
                     RYLGLSLPLLQDAFNGSAHPYDFLGKLGFTVLSLGAGYQGGEVTPLFEIGATLGATLA
                     PILHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGGQAASYFFMICLISFMCSGN
                     SGIYSAQKVEVKKGILFLPILGRISRQKEK"
     gene            complement(1474..2676)
                     /locus_tag="IXT22_001524"
     CDS             complement(1474..2676)
                     /locus_tag="IXT22_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4862895.1"
                     /translation="MNLTRDLIFLVIYILGMSGILYWRKRQSDPALFFYCGTWTFMMM
                     VTYFVVLEVFYHTFYFLIPLLFFSIFAFFYFKEKRRLINGVLFNTFLIVFGGYLGWLL
                     IETQNIFIGGLLALIGIPILILLAIGIYILIIFLFWNGVVVMKKESRSLANLLTLLLG
                     VALTIFLILDYTLVHWLPQWANALFAVIPFIFAYLLIVFFNFMTVSILYQFNRPRYNQ
                     DYIVVLGAGLIDGERVSPLLAKRINKAIAFYWAQSKATLNPPVLLMSGGKGTDEKVAE
                     AIAMKQYALEKGIPERDILVETNSTTTLENMLFSKEIMDQQMNGPYRAIFTSNNYHIF
                     RAGLYARQAKLNANGIGAKTALYYLPNAILREFIAILVLHKKRHLIICGLMIGFAVFS
                     ALILKFAQ"
     gene            3203..3928
                     /locus_tag="IXT22_001525"
     CDS             3203..3928
                     /locus_tag="IXT22_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HAQ4862896.1"
                     /translation="MNKKRFKRIERKFALTYDQAKYLKTLFPKQVVRDKYSDHFISSL
                     YFDTNDHHFLKEITTEKSYREKFRIRKYGDPQDISPIYLEIKRKFQGMTDKRRIKLAH
                     HELDDMLENIELAETTFSNLEEEYIFNEIQWLFRRLALEPKVYIYYLREAFVNRDSED
                     LRITFDQNIHYRLMNLTTWEHCTEDNLVAPEIDVLMEVKTTGEIPEWLQVGLDRMGKK
                     EIKFSKYKQVYKRYIQEDPLYVQ"
     gene            3918..4592
                     /locus_tag="IXT22_001526"
     CDS             3918..4592
                     /locus_tag="IXT22_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HAQ4862897.1"
                     /translation="MFNSVLKNEPSQLTLDDFFLCMVVSILLGILIAYTHMYQNNCTK
                     NFMFALIGLPTLVHTVILLINGNLGTGIAVLGAFNLVRFRSAQGNSRDIFSIFWATSI
                     GLATGTGYIVYALFVSSIVAAIQVIIFTLPIKNKHTVFNTEKTIKLKVSKSLFLSSII
                     EEKIAEYTENCNLKKVKINKETCSLHYIVKVKTSMLEKELVRTIMDHPEVISITVGMD
                     KSNKLL"
     gene            complement(4880..5164)
                     /locus_tag="IXT22_001527"
     CDS             complement(4880..5164)
                     /locus_tag="IXT22_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 family protein"
                     /protein_id="HAQ4862898.1"
                     /translation="MRQKCFLLLSHSQKVKPIFWLSIWDGFFKVSFHFPEKTREKLVT
                     LSLSEGTKEKIKTLQANGNKRKHLSVIFDVDHLEQLADIYQLAEFKKQNG"
     gene            complement(5168..5347)
                     /locus_tag="IXT22_001528"
     CDS             complement(5168..5347)
                     /locus_tag="IXT22_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862899.1"
                     /translation="MRFYNDGKAWLSKGEYKRLGQKCLTPRNKKKFTKIAFQIFVNFG
                     LFPKELLLLPPFIRF"
     gene            complement(5458..6765)
                     /locus_tag="IXT22_001529"
     CDS             complement(5458..6765)
                     /locus_tag="IXT22_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAQ4862900.1"
                     /translation="MFKKNTRFIVLLASLILCITSFLPSATVQADDAFKINAKAAFAV
                     DAESGKILYDQDGEKTMGIASITKIIGLYIVLEQIKEGKLSWEDKVAISDYAEKLSVV
                     PDLSNVPLHKENDYTVKELVDSAFIQSANASMVALAEKVAGSESKFLELMKKQLKDWG
                     IKDATIVNASGLNNSYLGENRPENTGETDENQLSAKDVAIVARHLILDYPEVLKITST
                     TNQTFGENTQSPVEMVNWNWMLPGFVNYHEGVDGLKTGTTDFAGACFVGTINKDGRRI
                     ITVVLNADNHEENPSARFNETSRLMDYCYDNWSEKELGKANASIPSLKDIKVKDGKET
                     SVNVALKSPVKVWVENGMDTGKLTITPTIDKKKVTDDQVTAPINKGTTVGSATIQLAD
                     DKLGYLEANQEPSTDIITTSTVEKANIFVIGWRHVTDFFSNLF"
     gene            7254..8360
                     /locus_tag="IXT22_001530"
     CDS             7254..8360
                     /locus_tag="IXT22_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862901.1"
                     /translation="MAKKEKELLSQLTSEGTKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKITSLLDDPSFWRSATTSVAVIVSPEQVFIHRLGI
                     PVDDQYYVSDLPYLLAIIKNGHFNYSYYLLGLNRDSMKLYEVTNKQVKEVALPEDAPR
                     DVVTALGSELTGGGLNYASNGSEGTTFHGVNPKDEEVEIDWVNYYQAVDDYLKDTFEN
                     PEKWPIFLFALPENQTMFKKVAKNPYYRSDVAISASPAQLSLKEIEAGAKKLSQELAV
                     KEASDYNKLLDKKFIDQLVDIIPAAKEGKISHLFIATSNLADGFGEDPETEYDRRQVL
                     NELADNVITNGGQVFILEQKDAPDEKSLVAILRY"
     gene            8951..9151
                     /locus_tag="IXT22_001531"
     CDS             8951..9151
                     /locus_tag="IXT22_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4862902.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            9298..12087
                     /locus_tag="IXT22_001532"
     CDS             9298..12087
                     /locus_tag="IXT22_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4862903.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIEAGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSSHTGMDTSRFIYHVLEEMKENPEPLDLSLEIIDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIMEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPGQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADVAHRGTGFLARNQSFYKQDFVRFLQKKIKQSNFLIVNHAFLVQETQRKEP
                     LLPASPYLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICVAEGLMNLVSSKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAMDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLLDFQAAMLPSTVWYPRYDHILYIGGTLKIGP
                     NRQYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLEAALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAIDEI
                     YQDIHEFLKKNEEGS"
     gene            12134..12661
                     /locus_tag="IXT22_001533"
     CDS             12134..12661
                     /locus_tag="IXT22_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4862904.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            12682..13872
                     /locus_tag="IXT22_001534"
     CDS             12682..13872
                     /locus_tag="IXT22_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4862905.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            13912..15210
                     /gene="asnS"
                     /locus_tag="IXT22_001535"
     CDS             13912..15210
                     /gene="asnS"
                     /locus_tag="IXT22_001535"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAQ4862906.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            16144..16818
                     /locus_tag="IXT22_001536"
     CDS             16144..16818
                     /locus_tag="IXT22_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4862907.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWREDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQKAGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            16815..17156
                     /locus_tag="IXT22_001537"
     CDS             16815..17156
                     /locus_tag="IXT22_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862908.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVGQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            17186..17545
                     /locus_tag="IXT22_001538"
     CDS             17186..17545
                     /locus_tag="IXT22_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAQ4862909.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     AFLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            17739..17927
                     /locus_tag="IXT22_001539"
                     /pseudo
     CDS             17739..17927
                     /locus_tag="IXT22_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            18069..20150
                     /gene="cadA"
                     /locus_tag="IXT22_001540"
     CDS             18069..20150
                     /gene="cadA"
                     /locus_tag="IXT22_001540"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4862910.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNELIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            20461..21927
                     /locus_tag="IXT22_001541"
     CDS             20461..21927
                     /locus_tag="IXT22_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4862911.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            22237..22710
                     /locus_tag="IXT22_001542"
     CDS             22237..22710
                     /locus_tag="IXT22_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HAQ4862912.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFIVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            22784..23224
                     /locus_tag="IXT22_001543"
     CDS             22784..23224
                     /locus_tag="IXT22_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAQ4862913.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQKGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            23237..23446
                     /gene="copZ"
                     /locus_tag="IXT22_001544"
     CDS             23237..23446
                     /gene="copZ"
                     /locus_tag="IXT22_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAQ4862914.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            23446..25632
                     /locus_tag="IXT22_001545"
     CDS             23446..25632
                     /locus_tag="IXT22_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAQ4862915.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            25652..27823
                     /gene="copB"
                     /locus_tag="IXT22_001546"
     CDS             25652..27823
                     /gene="copB"
                     /locus_tag="IXT22_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAQ4862916.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(27935..30106)
                     /locus_tag="IXT22_001547"
                     /pseudo
     CDS             complement(27935..30106)
                     /locus_tag="IXT22_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(30096..31037)
                     /locus_tag="IXT22_001548"
     CDS             complement(30096..31037)
                     /locus_tag="IXT22_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAQ4862917.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            complement(31182..32030)
                     /locus_tag="IXT22_001549"
     CDS             complement(31182..32030)
                     /locus_tag="IXT22_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAQ4862918.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            32384..33673
                     /locus_tag="IXT22_001550"
     CDS             32384..33673
                     /locus_tag="IXT22_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862919.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            33747..34316
                     /locus_tag="IXT22_001551"
     CDS             33747..34316
                     /locus_tag="IXT22_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4862920.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(34492..34758)
                     /locus_tag="IXT22_001552"
     CDS             complement(34492..34758)
                     /locus_tag="IXT22_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4862921.1"
                     /translation="MHRTFGSRGCPTLHLADRYAERKTPTLCFAFSARTRQAGIPLED
                     IKDFLGHKDVSTTQVYAHISPEVKKRSMNQLENYIEEQIKKHSN"
     gene            34753..35445
                     /locus_tag="IXT22_001553"
     CDS             34753..35445
                     /locus_tag="IXT22_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4862922.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
BASE COUNT        11679 a         6207 c         7379 g        10197 t
ORIGIN      
        1 gtaggcgttt ttttgaggag gaaatgagat ggaaaatcga ttacctgatc cattgaaggt
       61 gatcatctat atgatcaaat ggttattgat cacagcaatt ttaggtattt ttatgggaag
      121 tttatccgca ttctttctaa ctagtttgac tgatgtgaca gctattcggc tggagcatcc
      181 ttggttactt tttcttttgc cgataagtgg gggacttttt gcttatctat atacgacgta
      241 tgggggcaat tcttcccggg gaaacaattt agtgatcgat caagggaatg gaggaaatga
      301 aaagattcca ttacggctga tcccactgac cttatttggc accattacca cgcatctttt
      361 tggtggttct gttggtcggg agggtacagc ggtccaaatg ggcggggcac ttgctgagaa
      421 ttttgctcgt tggctaaaat tgaacaaaat cgagcgtgag attcttgtca tcagtgggat
      481 cagcgcaggt tttagctcag tatttgggac acccttggct gggacattgt ttggattaga
      541 agtattggca atcggaaaag tgagaaccga agcactgttt ccaagctttt ttgcagcact
      601 ttttgcgaac tttgtaacgg aaagtttcaa tgtcaagcat acccattatc aaatgggggc
      661 gattcctgca tgggaccctt cacttttctt caaattgttg cttgcgggca ttgcatttgg
      721 tatcattggc tggctcttta gccgttcgat cgtctggtta aaagcttggt atgcaaagcg
      781 gatcccccat ccagttttac gcaactttat tggaggagca gtcgtggtac tcgtagtagt
      841 gattttacag acgcaaagat atctcggatt aagcttacct ttattacaag atgcatttaa
      901 tggaagtgct catccttatg attttcttgg gaaacttggc tttaccgttc tatcacttgg
      961 cgcgggatac caaggaggcg aagtgacccc tttgtttgag attggggcaa ctttaggtgc
     1021 gacattagca cccattcttc atgtatcagt acctttttta gcaggattag ggtttattgg
     1081 ggtgttctct ggagcaacga atacaccgat tgcttgcttt gttatgggga tcgaactttt
     1141 tggaggtcaa gcagccagct acttctttat gatctgtttg attagcttta tgtgttcagg
     1201 aaatagtgga atctattctg cgcaaaaagt tgaagtgaaa aaaggaatct tgttcctacc
     1261 gatccttgga agaatctcac gacaaaaaga gaaataaaaa gaggttggga cagaagtgtt
     1321 taactccgag aaataagaag aaattcacga aaattgcttt ttaaattttt gtgaatttcg
     1381 cttatttccg aaggagttgc ttctgctccc accgtttatt cggagttaga gtctgtggca
     1441 aaactgattt ttagttttgt cccacgctct tttttattga gcaaatttga gaataagagc
     1501 agaaaatact gcaaagccaa tcattaagcc acagatgata agatggcgtt ttttgtgtaa
     1561 gacaaggatg gcaataaatt ctcttaagat agcattcggt aagtagtata gtgcagtttt
     1621 tgcaccgatt ccgtttgcat tgagtttcgc ttgtcgcgca tatagtccag ctctaaagat
     1681 atggtaatta tttgaagtaa aaatcgcgcg ataaggccca ttcatttgct gatccattat
     1741 ttcttttgaa aacagcatat tttctagcgt cgttgtggaa ttcgtttcta ctaaaatatc
     1801 acgctcggga atcccttttt ctaaagcata ttgtttcatt gcaatggctt cagctacttt
     1861 ttcatcggtt ccttttcctc ctgacatgag caagactggc ggattcaaag ttgctttact
     1921 ttgtgcccaa taaaatgcga tcgccttatt gatcctttta gcaagtaggg gagatacgcg
     1981 ttcaccatca atcaagccag cgccgagaac aacgatataa tcttggttat accttggacg
     2041 gttgaactga tacaaaattg aaacagtcat aaaattaaag aaaacgatga gtagataagc
     2101 aaaaataaac ggaatgacag caaatagagc atttgcccat tgtgggagcc aatggactaa
     2161 tgtatagtcc aatatcaaaa agatagtcaa agcgactcct aacaagagag tcaaaaggtt
     2221 ggccaaagaa cgggattctt ttttcatgac tacaacacca ttccaaaata aaaaaatgat
     2281 caaaatgtag ataccgattg ccaaaagaat taatattggt atcccgatca aagccaataa
     2341 cccaccgata aagatatttt gcgtctctat tagtagccac cctagataac caccaaagac
     2401 aatcaaaaac gtattaaaaa gtacgccatt gattaaccta cgtttttcct taaaatagaa
     2461 aaatgcaaaa atactgaaaa atagcaatgg aatcaaaaaa taaaatgtat gataaaaaac
     2521 ttctaaaacg acgaagtaag tgaccatcat cataaaagtc cacgtcccac aataaaagaa
     2581 tagagcggga tcgctttggc gcttgcgcca atagaggatg cctgacattc ctaaaatata
     2641 gataactaaa aatatcaggt ctctagtaag attcattgaa tgaactcctt tcgatttgta
     2701 aattttttct taaaaaagat agcatcattt agtagtaaat atatcgaata tagaaaagtt
     2761 agttactaaa tagtcaatca gttttttcac gacgtttcta ttataacgaa ttatgttgaa
     2821 aaaagctttt atcgaaaaca taaatcttca aattaacaga ttttttagac ctcgatcatg
     2881 atgaagactt ttgtagatac aaataactgt aacattgaaa atgaatgcga aaacgatatt
     2941 tttttttatt ggaaaatatc ggtcaagcaa taaaccagtt gcataataaa atgttaacgg
     3001 caacaaaatc tgtggaagga atgaaccgga tgatttgatg gaaaaaacaa gatagacaag
     3061 aagtatacat agtaaaacgt ggaacaagta ggccagaatg aaaaatcagt ttttatccac
     3121 tcgcttttct atacattcac tgtcacaaat ataatcgaaa gtaattctat tttgagataa
     3181 agtattttat aggagatagt atatgaacaa aaaaagattt aaacgtattg aaagaaaatt
     3241 tgcattaact tatgaccaag ctaagtattt gaaaacacta tttccaaaac aggtagttcg
     3301 ggataaatat agtgatcatt ttatttcttc cttgtatttt gatacaaacg atcatcactt
     3361 tttaaaagaa atcactacag aaaagtccta tcgagaaaaa tttagaatca gaaaatatgg
     3421 agatcctcag gacatatcgc ctatctactt agagataaaa agaaagtttc aaggaatgac
     3481 agataaacgt agaataaaat tagcgcatca tgagctcgat gatatgttgg aaaatatcga
     3541 attggcagaa accacattca gtaatttaga agaagagtat atttttaatg aaatacagtg
     3601 gttgttcaga aggttggcat tggagcccaa agtatatatc tattatttaa gagaagcatt
     3661 tgtaaataga gattcagaag atttgcgaat cacttttgat caaaatatcc attaccgtct
     3721 aatgaactta acgacctggg aacactgtac agaagacaat ctggtagcgc cagaaatcga
     3781 tgtgctgatg gaagtaaaaa cgacaggaga aatacctgaa tggttacagg taggattgga
     3841 taggatgggt aaaaaagaga taaaattttc taaatataaa caagtctata aaagatatat
     3901 ccaagaggac ccgctctatg ttcaatagtg tcttaaaaaa tgagccttct caactcacac
     3961 tagatgattt ctttttatgt atggtggtgt cgattttgct aggcattctg attgcttaca
     4021 cccatatgta tcaaaacaac tgtacaaaaa acttcatgtt tgccttgatt gggttaccta
     4081 ctttagtaca taccgtcatt ttgttgatca acggtaactt aggcacgggg atcgctgttc
     4141 taggcgcatt taacttagtg cgatttcggt ctgctcaagg gaattcaaga gatattttca
     4201 gtattttttg ggcaacgtcg attggtttag ccacagggac gggatatatt gtctatgcac
     4261 tattcgtgtc tagtatagtt gctgctatcc aagtcatcat cttcacgctt ccaatcaaaa
     4321 ataaacatac agtttttaat actgaaaaaa cgatcaagct aaaagtttct aaatccttgt
     4381 ttctttcgag tattattgaa gaaaaaattg cagaatatac agaaaactgc aatttaaaaa
     4441 aagtaaaaat caataaagaa acttgttcct tacactatat agtaaaagta aaaacgagta
     4501 tgcttgaaaa agaattggtt cgaacgatca tggatcatcc agaagtcatt tcgatcactg
     4561 taggtatgga taaatcgaat aaattattgt gataaccaag aaagtactta acaatgaagt
     4621 aagaccccag ttccaaagtt tagcggggac acttcaataa agtactttct tttttgtctt
     4681 cagcaactac tggtaaaact gagagcaagc tttcgtgaga gtacagcgat aaagatcaac
     4741 ctcccttttt atctcgagca atttccttgc aaggctgttt cgttgatctt aaacgagtta
     4801 gcaacagtca aagatgcgat ggccataaaa aaattgcatt aagttggctg gtatctgata
     4861 gctgggaatc taaggaagac tatccattct gtttcttaaa ttccgctagt tgatagatat
     4921 cagccaattg ttccagatga tcaacatcaa agataaccga aagatgtttc cttttattcc
     4981 catttgcttg aagagttttt atcttctctt tggttccttc actcaatgag agtgtgacta
     5041 atttctccct cgttttttct gggaaatgaa aggatacttt gaaaaatccg tcccaaatag
     5101 aaagccagaa gatcggtttt actttctgag agtgggacaa aagtaagaaa cacttttgtc
     5161 tcattcttta aaaacgaata aacggtggga gcagaagcaa ctccttcgga aataagccaa
     5221 aattcacaaa aatttgaaaa gcaattttcg tgaatttctt cttatttctc ggagttaaac
     5281 acttctgtcc caacctcttg tattcacctt ttgatagcca agcttttcca tcattataaa
     5341 accgcaaatt tcaaaaaaaa acgaacaata caaaaagcgt attgctcgtt tttctcttca
     5401 gtttctcaca cctaaacgac ttttgtctcg acctcttttt ggtgactatt catgatgtta
     5461 aaataaatta ctgaaaaaat ctgtgacatg gcgccaacca atgacaaaaa tattagcttt
     5521 ttcaacagta gaagtggtaa tgatgtctgt cgaaggctct tggtttgctt ccaaatagcc
     5581 taatttgtca tcagctaatt ggatcgttgc tgagccaact gtagtgcctt tgttgatagg
     5641 agcggtcact tggtcatccg ttactttctt tttatcaatt gttggagtaa tcgttaattt
     5701 tccagtatcc attccatttt cgacccagac ttttacaggg ctttttagcg caacattgac
     5761 ggaggtttct tttccatctt tcactttgat gtcttttagg cttgggatgc ttgcatttgc
     5821 ttttccaagt tctttttctg accagttgtc ataacaataa tccatcaatc gtgatgtttc
     5881 attgaatcgg gcacttggat tttcttcatg gttatctgca tttaaaacga ctgtgatgat
     5941 tcgtcggcca tctttgttga tcgttccgac aaagcatgca cccgcaaaat cagttgtgcc
     6001 agtttttaat ccatcgacac cttcgtgata gtttacaaaa ccaggtagca tccagttcca
     6061 attgaccatt tcaaccggtg actgtgtgtt ttcgccgaat gtttgatttg tggtactcgt
     6121 gatttttaag acttcaggat aatctaagat gaggtgacga gcaacaatag cgacatcttt
     6181 cgcagacagt tgattttcat ctgtttcacc agtattctca ggtcgattct cacctaggta
     6241 agaattgttt aaacctgatg cattgacgat cgttgcatct ttgatacccc aatcttttag
     6301 ttgtttcttc attagctcaa gaaatttact ttcactgcct gcaacttttt cagctaaagc
     6361 aaccatggaa gcattggctg attggatgaa agctgagtca acaagttctt tcactgtata
     6421 atcattttct ttatgcaaag gaacattcga tagatccggc acgacactta atttttctgc
     6481 ataatccgaa atggctacct tatcttccca agataattta ccctctttga tttgttcaag
     6541 tacgatatat agaccaatga tctttgtgat ggaagcaatt cccatcgttt tttcgccatc
     6601 ctgatcataa aggatttttc cactttctgc atctacggca aaggcagctt tggcatttat
     6661 tttaaatgcg tcgtctgctt gaacagttgc gctaggcaag aaagaagtga tacataagat
     6721 aagacttgct aatagtacaa taaaacgggt attttttttg aacatctttg ttctcctcat
     6781 ttttaaattg attcttacaa cttagaatat tatcagagag aacaaaaggt ttcaatggtt
     6841 ctgaaaaaaa acttataaag aacaagtctt attaatgaag aatcatagaa agttatcttt
     6901 tgggttcatt gacacgaact ttgactggct gaacttcggg ttcggttagg cgtgatgctg
     6961 caaaaagggc gcctgctgag agtgcgacca aactaaaaat catgaataat tgcataagat
     7021 cacctcgttc ttttttgttt ttttatagta tagcaagaga gtttgaagct actgttaagg
     7081 aaatgagcat ataattgatg aaagtatgaa aaaaatatga agtaggacaa cacaactaaa
     7141 aatcgatcag gtatttctct ggtagggatt cgttttattg tattgataaa atgggatgtg
     7201 gtagacttta tttacagata caaagaaatg atttttttag gaggggtacg tttatggcaa
     7261 aaaaagaaaa agaattatta tcacaattga cttcagaagg taccaaagga ccgtttgtca
     7321 cgattatgtt aaacacccat gttgcgcatc aagacgtaga aaaagatcaa atcaaattca
     7381 agaattttgc aaaggaagcg aaaaagcgct ttgaaaagaa atactctgag catgattggt
     7441 ctccattcca agaaaaaatt actagtttgt tggacgatcc gtctttctgg cgtagtgcca
     7501 caacgagtgt agctgtcata gtatcaccag aacaagtgtt tatccaccgt ttgggtattc
     7561 ctgtagatga ccagtattat gtgagtgatc taccttattt attagcgatc atcaaaaatg
     7621 gacatttcaa ctattcatac tatttattag gattgaatcg tgattcgatg aaattgtacg
     7681 aagtaacgaa taaacaagtc aaagaagtgg ctttgcctga agatgcacca agagatgtcg
     7741 tcactgcttt aggatctgaa ctaacaggag gcgggttgaa ctacgcatca aatggtagtg
     7801 aaggtacgac gttccatgga gtcaatccta aagatgaaga agtcgaaatt gattgggtca
     7861 attattatca agcagtcgat gactatttga aagatacatt tgaaaatcca gagaaatggc
     7921 ctatcttctt atttgcatta ccagaaaatc agacgatgtt caaaaaagtg gcgaagaacc
     7981 cttattatcg ttccgatgtt gcgatctcag cttcacctgc acaactttca ttaaaagaaa
     8041 ttgaagcagg cgcaaaaaaa ctatcgcaag aattagctgt caaagaagca agtgactaca
     8101 ataagttgct tgataaaaag ttcattgatc aactcgttga tattataccg gcagcaaaag
     8161 aagggaaaat atcccattta ttcattgcta catctaattt agcagatggt tttggcgaag
     8221 atccagaaac agaatatgac cgccgtcagg tgctgaatga actagcagat aatgtgatca
     8281 cgaacggtgg tcaggtcttt atccttgaac aaaaagatgc accagacgaa aagagtttag
     8341 ttgcgatctt acgttattga gtgaaaacta ccaaagtaga tgaatggtca ggcgttgata
     8401 gaagtgtata gctccgagag aaggagtttc ctctgtttca gccgttggat tcatcttgag
     8461 cgagagacaa aagctagctt ttgtctctcg ctcattattt ttgtgcttta gtcccattgg
     8521 ctttgcgagg ggaagatact tttctcaaaa aaacgaacct tgcagttgag agggggatag
     8581 atgcgcatac taatttttat cagttaaaaa atgatgtgga tcattagaga attccaaagt
     8641 tcgttcatcc tttttcagat aataaattga aattttttgc aaaagtgaaa atagcaaata
     8701 gaaattttct gaatcttata ggggtgattt cgagaaaacg ttcgtttatt tgcaaatata
     8761 tcttctaaat aagagaataa atacaaaaaa ataaggaaaa actctggcaa ttttgtaaac
     8821 ggtatgatat agtaagaatg tagtttttgt tcggtaatct gtggtagctt gtttcaaata
     8881 aacatcttcc agatatacac cattcaagta attgcaaaat atgtgttgat acacaaggag
     8941 gatttttatt atggaaacag gtacagtaaa atggtttaac tcagaaaaag gatttggatt
     9001 catcactgca gaaaacggaa acgatgtatt cgttcatttc tcagctatcc aaggcgacgg
     9061 attcaaaact ttagaagaag gccaagcagt aactttcgac gttgaagaag gtcaacgcgg
     9121 acctcaagca acaaacgtta ctaaagctta atttacctat attaaaaata aaagtccaga
     9181 catttatgtg tctgggcttt tttgtctttt tttccttaaa aagcgatgag agtatttttc
     9241 tgcactttgt agtataattt caaaagaaca ttagaggcag gagaagagga agatattttg
     9301 aaaccaagaa cttatgcagt cgttgatatc gagacgactg ggacgaatcc aaaagaagat
     9361 cggatcatcc aatttggctg cgtcatgatt gaagctggtc ggatcacttc acgtttttcg
     9421 atcgatattc atccagggcg gaagatttca aaacaaatcc agcatttaac agggatcacg
     9481 aatcaacgcg tccaaaaagc gccttatttt gaagatgtcg cccaaacgat ttacaatctt
     9541 ttggcagaca ccatatttgt cgcgcataat atttattttg attataattt tttgaaccat
     9601 gaactcatgc gatgcggact tcctagtttg aagataccgg gcatcgatac cgtagaactt
     9661 gcacaaattt tcttgccgac ggaaccaagt tttcgcttag ctgatttgtc agaaagcctt
     9721 ggctttattc atgagaatcc tcatcaggcg gatagtgatg ccgaagtgac aggtcagctt
     9781 cttttactga tcgaagaacg aatgaggaaa ttgccgatca tcacattaga gcagattgca
     9841 cgattaagta gccatacagg aatggatacg agtcgtttca tttaccacgt gcttgaagaa
     9901 atgaaagaaa acccggagcc ccttgatctc tcattagaaa tcatcgatgg gctagctttg
     9961 cagaaaaaag aagtggagct attcacatcc gtccattatg gcgagcggac atatccaaga
    10021 aaaaaacaag caaaagaaaa aatgtttggt aaaacactga tgtatcgaaa agaacagaac
    10081 aggctgatga atgctgtcta cgaccatttc acaaaagatg aatcaaaaga tttgatgatc
    10141 gaagcagcta caggaatggg caaaacgatt ggttatctgt tgcctttgag ttatttggct
    10201 acacctgaaa aaccagctgt catcagcacc gtttcgcttg ttttgcagca gcagatcatg
    10261 gaaaaagaca ttccattact gaatcaattg ctagatcagc cgatacaacc tgtgattatc
    10321 aaaagctatc gccactatat tgatttacag cgttttaaag gtacacttgt ggaaccgccg
    10381 ggacaaaaac aatatgcttt gtaccaaatg gctgtcttag tttggctaac acaaacgaag
    10441 accggtgatt tggatgaatt acatttaacc aatctgaacc atgcattctt tgcagatgtc
    10501 gcgcacagag gcactgggtt tttagcaagg aatcagtcat tttacaaaca agactttgtg
    10561 cgtttcttgc aaaagaaaat caaacaaagc aattttttga tagtcaacca tgcattttta
    10621 gtacaagaaa cacagcgaaa agaaccattg cttccagcta gtccttattt gttgattgat
    10681 gaagtgcatc atttgccgga aattgctgaa aaagtaaatg acaaacgact aagtattaac
    10741 tacttccata aacaaattca gcaactggaa gagccgaatc agttatttga ccgcatacaa
    10801 agttatttgc cgaaggaaca tgaagccttg cgctggttgt cgatttatcg agaagaactc
    10861 tctgcactat gcgaagcgca gatttgcgtg gcagagggat taatgaactt agtaagcagc
    10921 aagcaaccta acggacaata tccagaagaa gtcatgatga caaaagaaat gttggatcag
    10981 ctgccactgg aatctggaac agcaatggat catctgcaac ttttttatca agagatccaa
    11041 caactacaat cacagatgcg cttgactttt gagattatcc aagaaagttg gaccaaccag
    11101 atgcggatcg atttagcaag tttatatagc ttatttgatc aattagacaa gcaatacttg
    11161 ctgatggacc aatggctaga agactggcga gatcatttga tccattggtt cgttcccggg
    11221 aatacagcac agcagatgat ttttcatctc cttgattttc aagcagctat gttgccgtca
    11281 actgtgtggt atcctcgata tgaccatatt ctttatattg gaggaacact gaagatcgga
    11341 cctaatcgac agtatctctc taaacgactt ggcattgaag cagcacctct taaagtgatt
    11401 gcttctcctt atgattatga gaaacaggca agaatctatg tgccgaaaga agcacctgca
    11461 gtccatcaag tcagcaatca agcatatatc gattatttag aagcagcact cacaggattg
    11521 attgaacaag aagatcggcc gatccttgtt ttattcactt ctcatgatgt tttgcaaaag
    11581 gtatatcaga aaatgcattt gtctatgcta gaaaaaggac gtgaaattct tgctcaagga
    11641 tttggcggga gtcgggaaaa acttttgaaa cgcttcattt tgtcagaaaa aagcgtctta
    11701 tttggtgctg acagcttttg ggaaggcgta gatttacctg gagatgcttt gcagattgtt
    11761 gtagtcacac gtttaccctt cgacaacccg ttacgtccga tggtcaaagc taggaatgct
    11821 tatctggaat cagaggggat caatcctttt tatcaggaat ccgtgcctaa agcagctttg
    11881 aagttacgcc aagcattagg tcgtttgata aggacggaga cagatcgtgg cgtattactt
    11941 attttggatc ggagattagt cactgcaaaa tatggtgcac gaatcatcca tgcattaccg
    12001 aaaaaagtac cgataaaaga gctagctata gatgaaatct atcaggatat ccatgaattc
    12061 ttaaagaaaa atgaagaagg aagttaaagg tgccgtcttt tttcatcatt aaaatctgct
    12121 ataatgaaaa ggaatgaaga taaaggagcg acgacccttg aagaaaaaac agacaaagga
    12181 aaaaacgatt aatcgcgtgt tgcttggctt gatcgtattt ttattagcgg tcatcgtgat
    12241 cagctcgatt ttttacttgc gttccagtcg tccggcggtc caggcgaaaa aagaagcagt
    12301 agaaatcgca aagaaatatg caaatctcga ggaagccgat catttttact ggtttactcg
    12361 aaagaaaacg tacttttcat tgacgggtac gaatgataaa ggaaaagaaa tcgccgttat
    12421 cattcctaaa tctggtgaaa aagtaaaagt attggatcaa acaaagggac tgactgaaaa
    12481 cgaagcaaaa cagacaattg ctgcggccca tcctgaaatc caaatcgaaa aagctgcttt
    12541 agggatgtat gatgatcagc ctgtgtggga agtagtagga aaagaaacaa atgggaaact
    12601 gaattattac ctgattggct ttgaatctgg agatgaagtc aagacaatca agggaattta
    12661 aaaggtaaag gaatgaatgg gatggagtta tcaaaaagaa caaaacgatt agaaccgtct
    12721 gtcactttgg cagctgcggc aaaggccaag gcattaaaag caaaaggcag agatgtgctg
    12781 agtttgactg tgggagaacc ggattttgcg acaccagaaa acatccaaga agcagcaatc
    12841 gaagcaatcc gcaatgggaa agctagctat tatacaccaa cagcaggaat cccagagctt
    12901 cgacaggcaa tcgttgatta tctgaagaaa aactatggac ttgtctatga accttcacaa
    12961 acagtcgtaa cagacggagc gaaatttgct ttgtataccc ttttccaaac gatccttgac
    13021 ccgcaagatg aagtcatcat tcctgtgcct tactgggtca gttacggtga gcaagtaaaa
    13081 ctggcagaag gacttcctgt ctttgtgaaa ggggaagaat ccaatagctg gaaagttact
    13141 gttgagcagc tagaacaagc acgttcagaa aaaacaaaag ccgtaatcat caattctcca
    13201 tcgaatccga ctggaatgat ttatagcaag aatgaactgc aggcaatcgg tgaatgggca
    13261 gtaaaaaatg atattttgat agttgctgat gatatttatg gccgtttagt ttataatggc
    13321 aatgagttta ctccaattgc aacgatttca gaagcaatca aaaatcagac catcatcatc
    13381 aatggcgtgt ctaaaacata tgcgatgaca ggctggcgca ttggttatgc ggtggggaat
    13441 tctgagatca tcaatggaat gattgctgtt gcttcccagt caaccagtaa tccgacagca
    13501 gtcagtcaat atgcagctgt tgaagcattg aaaggcgagc aagatacagt ggaagaaatg
    13561 cggaacgcct ttgaagaacg cctgaatacg ttatatccgc ttgtggcaga actgccgggt
    13621 gtttctcttg aaaagccaca aggagctttt tatctttttc ctaatgtaaa agaaacgcta
    13681 cgcatgtgta aatatgaaaa tgtcacacaa tgggtagaag atcttttaga agaaacaggg
    13741 gtagcgcttg tgactggcga aggctttggg gcaccagaaa atgtccgcat gagttatgcc
    13801 actgatcgcg ctacgttaga agaagcggta cgcagaatca agcaatttat tgagagtaaa
    13861 agtcaaaatt aatcctgaag aaattcaagg aatataaaag gagagtcata cgtggaacaa
    13921 attcaaatca tcgattcgaa aaaccatgtg ggagaaacag taacaatcgg cgcttgggtc
    13981 gcaaataagc gatcaagcgg aaaaatcgca tttttgcaat taagagacgg aacagccttt
    14041 ttccaaggtg tagttgtaaa aagcgaagtg ccggaagaag ttttccaaac agctaaaaat
    14101 ctacaccaag aaacatccgt gttagtaact ggagaaatcc gtgaagacag tcgttcaaaa
    14161 tttggttatg aaatcggaat tacaaatgtg gaagtggtaa gcgagagcca cgattatccg
    14221 atcacaccaa aagaacacgg aacagacttc ttgatggatc atcgtcattt atggctgcgt
    14281 tcttcaagac aacatgcgat tatgcagatc agaaatgaaa tcattcgtgc aacgtatgaa
    14341 ttctttaatc aacatcattt tgtcaaaatc gatccgccga tcttgactgg ttctgcacca
    14401 gaaggcacta cggatctatt cgaaacaaat tactttgatc aaaaagctta tttatctcaa
    14461 agtggccaat tatacatgga agctgctgct atggctttcg gaaaagtctt ttcattcggt
    14521 ccgactttcc gtgctgaaaa atcaaaaaca cgacgtcatt tgatcgaatt ctggatgatc
    14581 gaaccagaaa tggctttcac tcatcaagaa gaaagtttag aagtacagga acaatatgta
    14641 gcattcttag tacaaaatgt tttagatcat tgcgaatacg cattagatgt actaggacga
    14701 gacaaagaag tcttaaaaac ttatacaaaa ttgccattcc ctcgtattac ttatgatgat
    14761 gcgatcgaat tactgaagaa aaatggattt gatgacatcg aatggggcga agactttggt
    14821 tcacctcatg aaacgttcat tgcgaattca ttcgaacagc ctgtctttat cctaaactat
    14881 ccaaaagcca tcaagccatt ctacatgaaa ccacatccaa caagagaaga cgtggtgatc
    14941 tgtgcagata tgatcgcacc agaaggttac ggtgaaatta ttggtggaag cgaacgggca
    15001 acagactatg atttcttgct agaacaaatc cgtaatcacg gtttggatga aaaagaatat
    15061 tcatggtatc ttgatctacg taaatacggt tctgttccgc actctggttt tggtctaggc
    15121 cttgaacgaa cagtcacttg gattgctggt atcgaccatg tgcgtgaagc tattccattc
    15181 ccacgtttgt tgaaccgaat ttatccataa gaggttgtga aatcagtgcc ttgacctgag
    15241 tattagagaa acaaaacgga aaaatagctt ctcatatttt actgtttttt gagctaatat
    15301 cgagggtcag ctgattgaac accgtttata tcaagaggtt gtgcgtctgc cgttcagctc
    15361 cgagtcacaa ggagtaattt caaaaaaaca ttttttcatg tttgatgact attgtgactt
    15421 gtgaccaagg agttggccgg agagcaacgt ttatttaaaa aaaagaactg cgaactctcg
    15481 cagttctttt tttttaaata cgggataaag gaagtttcca gcagataaga gaagaaagca
    15541 aaagaaattg ctatttgatt cacaaggttc tataacgaaa tcgcaatcaa tcaaacatat
    15601 acaaagaagg ttattcaaat ggaaatctga tttgatgatg cttctgctgt tgaaataaag
    15661 cagcatctag cacctgaaaa caaactaata gtaacattcg aagatggagt aggtccgtat
    15721 tttcagcatg caatgatcca tatgtaagtt caattcaccc ttgaaatcat cggaccagat
    15781 aaagttatgg ccaatctatc ccaagcaatc tagaagagat attagtaaag gaacatttac
    15841 tggaagtctt agatgagcct ataaatatat gttctgatgg cgtcatcaag tggtctgatt
    15901 gacggaagct taggtgtgat cgatctctct ggaccaaaca atgaaggaat caaggggaat
    15961 ccagcacgtt aagaaaaaaa tagcataaaa aactagacac ttgatgagcg ttcattcaat
    16021 tgtttgaagg gactaggctg gtgtcatttt ttatacatat attttctctt tcgtcttgat
    16081 agggcttatg ggataatata aggaagaaaa tcatcgtttt attcaaaaag gagtttttga
    16141 caaatgaaaa aacgtatatt atttatcggt gacagcatta cagacgcagg aagagaccga
    16201 gcagaagcaa ctgatctagg taaaggttat ccacttttga ttgccggaaa actaatctcc
    16261 caatatccaa cgatggaatt tgaatgcatg aaccgtggga taggaggaga caaaattgca
    16321 gatctgcaag tacgctggcg agaagattgt ttagctttac aacctgacta tgtatcgatt
    16381 ttgatcggaa tcaatgatac ctggcataat actagcgatc aggctatatt cggaactgag
    16441 aaatctgctc agcaatttga atccgtttat cgaaaattac taaatgaact tcaaaaagcg
    16501 ggaatctgca acatcatctt gatggagccg tttgtacttc ctataaccga cgaccgtcat
    16561 ggctggcgta aagacttaga ccctaaaatc caaattgttc gtaaacttgc taaggaatat
    16621 ggcgcattgc tggttccttt agatggcata ttcaatgctt tagggattgc ttatggtttt
    16681 tcgaaatata caagagaaga tggggtccac ccaacgattg gcggacatga gatcattgca
    16741 caaagctgga tagatgcaat tgccgcagtc gattttttta gtggagataa aaatgagcga
    16801 aagaaaagtg agaaatgatg gaaatacggt gggcagtaaa agaagatcta cctcaaatca
    16861 atcagctgat tactgatcat ccagaatcat tcgtaaaagc aaaaacggca gctgacctaa
    16921 atgataagaa taaactattg ctcgttgctg taacaaaaga aaaacggatt atcggttttg
    16981 cgcaagcgga cgtgcaacag tcagaagaac gggtgggtca gcgaccatca ggaaaactaa
    17041 tccaacacac attagtaaca aaagaaaata cggaagaaat ccaaaaaaaa tttgcagaat
    17101 atttgatgct ggaagctaaa aaaagaagaa taaaatcaat ttttgcccag ttttaatcaa
    17161 aaacagtaat agaaggagaa atacaatgag ttgtttagga aatgtcatct ggtttatatt
    17221 cggcggacta atcggtggtc ttagctggtt agcagcgggg atactttggt gtatcacgat
    17281 cataggtatc ccaatcggta tgcaatgttt taagatcgcc ttcctttctt ttgcgccttt
    17341 tggcaaagaa gtaatttatc accagtctgg catgtcattg atcgttaata tcatctggct
    17401 gatcgtttca ggcctaccaa ttgctctcgc acatgtcgtc agcggcatcc ttctatgtat
    17461 cacgatcata gggatacctt ttgccaagca atctttcaaa cttgctcgat tggcgttgat
    17521 gccattcggt gcagaaattg tataaaagag aataataaag gttagataaa gcatagagtc
    17581 aggtgggata catgtatttc acctgactct atgcgttttc ctgtataagt tcttccatgt
    17641 gacttttacg tcttttattt atatggggtt actgtttatg gaaagttgaa ataattttca
    17701 ttaaagaact ctttctatat ttttgaaagc gtagtggagc ttcgtatatc tgggaaggac
    17761 attttgcagg gattgaaaaa agatattgtc ctatcgaaaa attaatgaat ttagacaaat
    17821 tgccagcaac aggcttcaaa cttagttgct atcctgtcaa gatcaagaag gcaagtgcgg
    17881 gttggataag agcagtggca atgatcgaag agaaaaagaa agaataagcc aaaacatctg
    17941 tatggaagaa attttccgat gcagatgttt ttcatttttt ctttcggata ccttgacata
    18001 tgaataacca ttcatttata attagttatg aagagatatt catatgttga ggcgaggagg
    18061 tcattaaaat gaaaagttac agattagaag gtttagattg tgcgaactgt gcaatgaaaa
    18121 tcgaaaaagg agttcagaaa atcaatggag tcaaggaagc aacggtaaac ttcacttctg
    18181 gaaaactaac gattgacgcg gaggaagatc atttggctac gattgaacaa gaaacaaaaa
    18241 aagtagtgaa ggaattagaa ccagatgtca aagtaacaga aatagataag gaaaaagtat
    18301 ctgaacatgg aaatgaaaaa gagagaaata cgctgttccg gattttattt tcccttgcag
    18361 gtatcgcttt attgctatta tttgatttta atgaactaat tcgcttgata gggtatttat
    18421 tgatttatct gctgatagga tatgatgtag tgaagaaggc agtgatgaat atcgtcaaag
    18481 gaaaaatctt tgatgagaat tttcttatgt ctgttgctac gattggcgct atgttgatcg
    18541 gtgaatatcc agaagccgta gcagtgatgc tattttatca aatcggcgag tatttccaag
    18601 gattggcagt cagtcattca agaaaatcga ttcgcgaatt gatggcgatc cgtccagaaa
    18661 cagctcacgt gcagacggcg gaaggattga tgaccgtgaa ccctgaagac gtgctgatcg
    18721 gtcagtttgt acttgtgaag cctggtgaac gtgtaccgtt agatggaacg atcatcgaag
    18781 gagaatcatt agtcgatacg tcagcactta caggagaatc agtccctaaa tctgtatatg
    18841 ttggtgaaac agtattaagc ggatttatca ataaaaataa accattttta gttcaagtag
    18901 aaaaatctta tgaaaattct actatcagca aattattaga attagtagaa aatgccagca
    18961 gtaaaaaagc accagctgaa aatttcatta ctaaattcgc gcgctattac acaccagtcg
    19021 ttgtaggatt ggccgtttta ttagctgttt tacctccact tgttgtttct ggagcggcgt
    19081 tttctgaatg gatctatcga gcattgacat ttttagtgat ctcatgtcca tgtgcattag
    19141 tgatttccgt gccacttagt ttctttggcg gtatcggagg agcaagtaaa atcggtgtat
    19201 tagtaaaagg ttcaaattac ttggagttgc ttgcgcaaac cgagacagtg gtattcgata
    19261 aaaccggcac attaacgaaa ggcgactttt cgatccagac gatcgataca aaaatcgatc
    19321 caaagatatt catgcaatat attgcgagtg cagaacagtt ttctacacat ccgattgctc
    19381 aatctgtttt agaaggctac gcaggtccgc ttttaccaac agctaatatc caggaatttg
    19441 caggtgaagg gatcttagct gaagttgatg gcaaacaagt attagtaggt aatcacaaat
    19501 tgatggaaag atttgaaatc tcttttcctt caagtcaaga aatcggtaca ttgctttatc
    19561 tagcaatcga tcaaagttac agtggttatc ttgttattgc agataccttg aaagaagatg
    19621 ccgtagacgc attggttcaa ttaaaacagg ctggtgtgaa aaacacagtc atgttgacgg
    19681 gcgactcgaa aaaaattgct gatcatatcg ggaagcaagt aggcgtggac aagatatata
    19741 gcgaattgct tccagaagat aaagtgcagc ggttagagga aatcttacaa agtaacaata
    19801 aaaagaccgc atttgtcgga gatggaatca acgatgcacc ggtgctagca agagcagatg
    19861 taggaatcgc aatgggtgga ttgggaagcg atgctgcaat tgaagcagca gatgtagtca
    19921 tcatgaatga tcaaccatcg aagattgcag aagcaatcca tttagcaaag aaaacattga
    19981 aaatcgtcaa acaaaacatt gtctttgcta ttgggataaa aattttggta ctttccttag
    20041 gtgcttttgg ttttgcatca atgggagatg cagtatttgc agatgttggg gtgacagtat
    20101 tagctgtttt gaatgccatg cgaagcttgc atgtaaaaaa taaacgttga tcaatgaaga
    20161 ggacgaatga acgtcctctt ttttttatat ccttttctta atgaaaaatg taaagaaaat
    20221 agataggatt ataaaataac taatgttttt aattttgcag aaaattcaaa atagcttgaa
    20281 attcaataag gtcaatgaaa taaaagaaaa taacttattt ttttgatgga aaaaatatga
    20341 aaaaacgatg tgtattaaat aaaataatac acacataaaa taacactgtc ttgtaagttt
    20401 gttaaaaatt gaatatgatt acatctggat aacaaatttt tatcataaag gagagaacga
    20461 atgaacaaca aacaattacg ctggtttact gttgcgttaa ttgcatttaa catggtttgg
    20521 ggcatgggga atgtagttaa taactatgct cagcaaggag tatcagttgt cacctcttgg
    20581 ctattgattt tggccattta ttttattcca tacgcattga tcgttggaca attaggatca
    20641 gccttcaagg atagtaaagg aggcgtcagt tcatgggtcg aaaatacgac atctaataaa
    20701 cgactggcat actatgccgc ttggacttac tgggtcgtcc atattcctta tttggcacaa
    20761 aagcctcaag caattctgat tgctggtggt tgggcagtcc aaggaaatgg aaatatcgta
    20821 aatacgatgt cagtacaaat ggtagcagtt atttcactta ttatatttct tgccttttta
    20881 tatttatcaa caaaaggact ttctactttg aaagtgattg gcggactggc cggaacagcg
    20941 atgttcgtca tgtcgatctt atttattctt ttagctgtaa cggcaccgtt catcaatcca
    21001 acgatggaat ttgccacacc acatatgaat caagtgaaaa catatattcc aacatttgat
    21061 ttcagttatt tcacaaccgt ttcgatgcta gtatttgcag ttggaggggc ggaaaaaata
    21121 tccccttatg tcaactctac aagaaatcct gcaaaggaat ttcctaaagg gatgatcttc
    21181 ttagcagcaa tggtagggat ttgtgctgta ttaggctcag tcgcaatggg tatgctgttt
    21241 gctagcgata atatccctaa agacttgatg gcaaatgggg catacagtgc ttttcaaatt
    21301 ttaggtaatt actatggtat cggtaactca ttgatgatca tttacgcatt gacaaacatg
    21361 attggacaaa tctccgcatt agccttttca attgatgcac cactaaaaat cttgttagca
    21421 gatgcggatc cagaatttgt accaaactgg ctacgtaaac gtaatcgtaa aggtacattg
    21481 gtgaatggtt atcttctgac aggtatacta gtaggaatca ttattttgtt gccgatcttt
    21541 ggtatcaaag atatgaatga attagtaaaa tggttgacga acttgaactc agttgtcatg
    21601 ccaatgcgtt acctatgggt gttcttggca tatatgatgt tgaataaagc ttataagaaa
    21661 ttcaattctg aatataaatt tgttaaaaat ccaaaaatcg gttttatctt tggtgcttgg
    21721 tgctttgcct tcactgcgtt tgcatgtatc ctaggaatgg tgccaaaagt agattatact
    21781 gctgatccta aagcatggtg gttccaatta ttcacgaata tcatcacacc aattgtcttg
    21841 atcttattag gtatgatctt gccagcaatt gctcgtcgag acaaaaacaa agaaattact
    21901 gaaccagaaa cagtggttca gccttaaaat agaaatactt gttacaagag gttgtgacag
    21961 aagctacttc tggaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcaagtaa
    22021 taagaacagc caaacaaaaa tagctcctca tattttgccg ttttttgagc taatgctgaa
    22081 ggtcagctga ttgaacacca tttattcgaa acaagggact ttgacacgac ttttgtcaca
    22141 gtcccttgtt tttttgcggc gttataagtg gtatgatcga accaaattcc aaagagaagt
    22201 gagggagaag aatgaagatc atcgtgattg gacaaagtgg gtcgggaaaa tcgtccctcg
    22261 caaggaagat caaagaaatc accggctttc cgcattcagg caaaaaagtg gtttttgcaa
    22321 gaacagcaat cgtttatagt atctaatccg tcatggatcg ttgaaggaaa ttatacttct
    22381 acgttagagg aaaggattaa agaagcagat aagatcattt ggcttaaagt gccgcgttat
    22441 ctcgccatct accgagtagt ttggcgttct ctaaaaagaa agataaacaa aaaatctcgg
    22501 ccagatatgc ctgaatcatt ttcggagaaa ctaaacagga aatacttaga atttttatct
    22561 tttatctggc attttgaagg aaacaatgaa ccaaaaatac agcagctgat ccaagtagct
    22621 aatgcaagaa ataaactgat catccttaaa acaagacgag agaaacaaga atttttaact
    22681 aaattgaaaa tagagagcaa aaataattga cagtttttgt ttacaagcgt aatctgtatt
    22741 cataagctaa tgattacatt tgtaaacgaa aggtgtgaaa taaatggaaa aagtcaaaac
    22801 gccagtaaag atcagtgatt cagagtggga gatcatgcgt gttatttgga cacttggaca
    22861 gacgacagcc caagaaatca cgcagatctt agctgattcg atggattgga aaccagcaac
    22921 gatcaaaact ttgctgggac gtttggtaaa aaaagaagtg atctggacag aacaaaaagg
    22981 aaaaaaattc atttatcatc cagctgtctc ggagatggaa acagttcgca gtgcgacgga
    23041 aaatcttttt tcccatatct gtgcaaaaag gattggagag acgattgcgg atctagtaga
    23101 agaagctact ttgactcaag aagatatcaa tgagattttg aaacaactgg aacaaaagca
    23161 accagtagat acgatcgaat gtaactgtat cccaggtcaa tgtgaatgta aacaacatca
    23221 ataggaggaa gaaaaaatga aacaacaatt ttcaatcgaa ggtatgagct gcaatcattg
    23281 tgcagcaaga gtagaagaaa cagtaagcgc acttgacggc gtgcaaaaag tgaaagtaaa
    23341 tttgaaaaaa gcaaacggta cggtcaagtt tgatgaaaca aaagttcaat ccgaaaagat
    23401 ttgtcaagca atcaatggat tgggttataa agcagaggtg atttgatggc aacagcagaa
    23461 accaaaatgg atacgttcgt cattacaggt atgacttgtg caaattgttc tgctaggatc
    23521 gaaaaagagc tgaacggaca acctggtgtg gtcaatgcca cagtcaactt ggccactgaa
    23581 aaagcaagtg tcaaatatga agggacgacc actgaaaaat taatccaaag cgtagaaaac
    23641 atcggttatg gtgcaatttt gtacgatgaa gcccacaaac aaaaaattgc agaagaaaag
    23701 caagcgtatt tgaaaaaaat gctattcgat cttatattga gtacggtttt gactttgccg
    23761 ttgatgttgt caatgattgc tatgatgtta ggaagccatg cggcgattgt tcactttttt
    23821 cattttccaa tcgtccagtt agtgctgtct gctcctgtcc aattttatgt cggtgctcgt
    23881 ttttataaag gtgcgtacca tgcaatcaag acgaaagcac caaatatgga tgtattggta
    23941 gcaattggaa catcggctgc ctttgcattg agcatttaca acggattttt ccgtggacac
    24001 ccccaagatc tttattttga aagcagcagt atgatcatca cgctgatttt gctcggcaaa
    24061 tatttggaac atacagcaaa aacgaaaaca ggtaatgcaa tcaaacaatt gatgtctctt
    24121 caaacaaaaa ccgcccaagt gataagaaac gggaaagaag aaacgttagc gattgaagaa
    24181 gtagtcgttg gtgatcaact agtcatccgt cctggtgagc agattccagc agatggtcga
    24241 attatttcag gaagcagtgc gatagatgaa agtatgctta ctggtgaaaa tcttcctgta
    24301 gaaaagaatc cggatgacac gctttttggc gggacaatca atacgaatgg tctgctacac
    24361 atggaagtca cacaagtcgg caagcagaca gtattagcgc aaatcattca aatggtggaa
    24421 gatgctcaag ggagcaaagc cccaatccaa aaaatcgcag atcggatctc agggattttt
    24481 gttccgatcg tattagtcat cgcgtttatc acgctcatag ctacaggttt gatcactggt
    24541 gattggcaac tcgcattgat ccatagtgtc tctgtattag tcattgcgtg tccatgtgca
    24601 ttaggtttag cgaccccaac agctattatg gtaggaacgg gtgttggtgc acgaaatgga
    24661 attttaatta aaggcggaga agcattagaa gcagctgctc acttagacag cattgttttg
    24721 gataaaactg gaacgattac agaaggaaag cccaaagtta cagatctagt cggttcaaaa
    24781 gaagtcctat ctatttttta tactttagaa caagcttctg aacatccact aggtaaagca
    24841 atcgtggaat acggaaaact gcaagaagca gcaacatacg atatgattga ttttacagcc
    24901 cacccaggtg ctgggatcag cggtacgatt aatggagtac gctattttgc gggtacacgt
    24961 aaacgattaa ttgaattgaa cctatcattt gatgaatacc aagaacacgc gttagaatta
    25021 gaacagcagg gaaaaacagt catgttttta gctgatgaaa agcaagtgat cgggtggatt
    25081 gccgtggctg atcaaatcaa actagaagcc aaacaagcaa tcaagcagct ccagaataaa
    25141 ggattagatg tttttatgct gacaggagac aacaaactgg cagccgaaac gattggtaaa
    25201 caagttggta ttgatccaaa gcatatcttt gctgaagtac ttccagagga taaagcagcc
    25261 tacgtagaaa aacttcagaa agatggcaaa aaagtcggta tggcaggcga tggaatcaat
    25321 gatgcaccgg ccttagcatt agctgatgtc ggtatggcaa tgggaagtgg aacggacatt
    25381 gcgatggaaa cagccgatgt gacgctgatg aatagcagtt tggcatccat tgcacaaaca
    25441 atcgagttgt ctaggttgac attgagaaaa atcaaacaaa atcttttctg ggcttttgtc
    25501 tataatacga ttggtattcc ttttgccgca ctaggctttt tgaatccaat cattgcagga
    25561 ggagcgatgg cgtttagttc cgtcagtgta ttgttgaact ccctgagctt aaatcgacac
    25621 atgaaaaagt aagagaaggg atggagtaaa aatgaatggg aacgatatgg agaaaaaaca
    25681 tgagcataaa aaagaagtag taaacaaaga aagtacagaa tctcatgaaa aacagatgga
    25741 gatgaaacat gaccatagtc agatggatca ttccatgcac atgggacata accatggaga
    25801 tatagcaaac agcaaacaaa tggaccattc gatgcacatg gatcacgaac acggcggcat
    25861 ggatcattcc atgcacatgg ggaatttcaa acaaaaattt tggctatcgc ttatcctagc
    25921 tatcccaatc attctttttt caccaatgat gggaatggaa tttccatttc aagtaacgtt
    25981 tcctggttct gattggctcg tattgatctt agcaactata ctatttatct atggcggtca
    26041 gccattttta agtggagcta agatggaatt gaaacaaaaa agtcctgcta tgatgacact
    26101 gatcgcgatg gggattacag ttgcatatat ttatagtgtc tattcgttta tcgcaaatct
    26161 gctcaatcca catacacacg tcatggattt cttctgggaa ttggctactt tgatcgttat
    26221 tatgctacta ggtcactgga ttgaaatgaa tgctgtgtcg aatgccagca atgctttaca
    26281 aaaactagca gaattactgc cagaatcagt gaaacgcttg acgaaagatg gaaaagaaga
    26341 gacagtttca ttgaaagaag taaacgaagg tgatcgtttg atcgtccggt ctggtgataa
    26401 aatgccaaca gatggtgtaa tcttgaaagg tgaaacaatt gttgacgaat cagctgtgac
    26461 tggcgaatca agaggaatca aaaaacaagc caatgacaaa gtgattggcg gttctatcaa
    26521 tggggatgga acgatcgaaa tcgaagtaac tggaactggt gaaaatggtt atctagcgaa
    26581 ggttatggaa atggtgcgaa aagcacaagg agaaaaatcc aagctagagt cattatctga
    26641 caaagtggca aaatggctgt tttatgtcgc attaattgtg ggtatcctgg cattcatcgc
    26701 ctggttgttc ttgacagatc ttcctaatgc attagaacgt atggtaacag tctttatcat
    26761 cgcctgtcct catgctctag gtttagctat cccattagtt gttgctcgct ccacatcaat
    26821 agcagctaaa aacggattac ttttgaaaaa ccgcaatgca ctggagcaag ccaatgatct
    26881 agatgtgatc atgctggaca aaacaggaac actaacagaa ggaaaattta ctgtaacggg
    26941 tgtcgaagta cttgatgatg cgttcaataa aaatgaaatc cttcaatatc taggagcctt
    27001 ggaagcgaat gccaatcatc cattggctgt tggcattatg aattatttga aagaacatga
    27061 aatcaagcct tatcaagctg aaaatctaaa aaatctttca ggagtcgggc tagaggcaac
    27121 agtcaaaaaa caacaagtga aaatagttaa tgaaaaagaa gttgagcgtc tcggattaaa
    27181 cgtagaacaa gcattattga aaccttacca agaacaagga aataccatca gcttcctgat
    27241 tttagaaaat catctagctg caatcgttgc tttaggtgac gtagtaaaaa cagaagcaaa
    27301 agaatttatc cgaacattga aagaaagaaa aatcactcct gtcatgctta ctggtgacaa
    27361 taaaaacgct gcccaagcag tagcagatta tttagggatc gaagaatatt atggcggttt
    27421 attaccagat gataaagaag ctgttgtcca gaaatacctt gaccaaggga aaaaagtaat
    27481 catggtgggt gatgggatca atgatgcgcc aagtttagcc cgtgcttcaa tcgggatggc
    27541 aatcggtgca gggacagata tcgcaatcga ttctgcggat gtcgtattga caaacagcga
    27601 tccaaaagat attttgcatt ttcttgatct agccaagcaa acgcgaaaga aaatgatcca
    27661 gaacctctgg tggggggcag gttacaatat tcttgcaatt ccgctagcag ccggaattct
    27721 tgcgccaatt ggtatcatat taagtccagc agttggtgct gtcttgatgt cgttaagtac
    27781 ggtagttgta gctctaaatg ctttgacatt gaaaatcaaa taataatgaa aaaaggttgt
    27841 gacaaaaaac gtgtcacaac ctttttttcg agtaatcgat actcaatcag ctggttctcg
    27901 gcattccaga agtagattct ccagaaattt tatcttattt tttgaagcgg ctcccttttg
    27961 tcagaatttt tttgtatacc gtttttctta ttatacgcgt tatttctaaa taggtttttt
    28021 tatcgaattt taccggatct gcttgtcgtc catatatttc tgcttcatat tgagtagtta
    28081 atcgaatgaa acgcagatct agcttgaatt cttgttctat tcgcaggcta tattcctgca
    28141 aagattctgc gggtttgcgc ggtaccaatg tttccaaagg gttaagaagt ttttgatatg
    28201 caatcgtatt agtagaagca aaaaaatgaa gatagataag ataacttgtc cagcgcagag
    28261 attttctgaa taacaataga aagaacaaca agacggataa acacactcca aggctgaata
    28321 agacgatttt ataagctggt gtgagtgttg tttcttctga tggaatgacc tcagatctct
    28381 cactggaaat agtttctgcc atattttcgc tttcatttgg ttgttcgata gcaggctgga
    28441 cggtttcggt tgtttcagca actggttgtg aacccattgg attggcaaat gaaggggttg
    28501 gttcaaatgg aagccagcca aatccaggaa agtatacctc tggccaagaa tgagcatgac
    28561 tattgagaat gctgtattcc tcattccctt gattatctgt gcctgttctg agcccatttg
    28621 taaaaccttt tgtccagcga gctgggatac caagtgttcg aagaaggacg accatagaag
    28681 ttgaaaagtt gtcacaatag ccgacttttg aatcaaagag gaaataatcc acataatcgt
    28741 gttctttcgg agtatgcccg gtatccgttt tggaatagcg gaaatttccg cttgttttta
    28801 aatactgtta gacagcttcg actttacgaa ttaaagttgc ttcatttttg gtcaattcga
    28861 ccgccaagtc ctcaatacgt ttaggcaaac tttttggcaa ttgaagattt gtctgctgat
    28921 tttctaaatc atcagctttt aactgactgc tttttaattc ttctctcgta aaaactaacc
    28981 tttctgtttg taaagttgca gaacgtgtcg attcattcgg gacaggaatg aatcgctggc
    29041 tttcaggcaa atagtaaagc gtttgtccac tagctaatga aaaatcagtc aaggtagtat
    29101 ttccataagg ataaggtaag aaagcttgtt tttttagggt caatgtaatg ttttctttgt
    29161 cttctataac ggtttggtag ctcgtgatgt caacagggaa ttcttggatt ggttggatgg
    29221 gtgcgtcctg atcttctatc catccagaac cggtgtaatg atttttattt tcgatcttcc
    29281 aatagccatt tcctttttgg ttcgctgtaa aaacaacttc gccattatca tataaaggtc
    29341 caccaagctg ttcatcattc tcactgaagc ctgttcttgc acttccggtt aattgatact
    29401 catggagtgt gtcataaagc ccttcatcat taagatattc tcggatcggt tcactcgttt
    29461 cctcgagaga ttggtgtact ttcggaagat ataaaggcaa gatagcgcta aaagttaaga
    29521 aacaaataag cagaactgta gtcaatgact ggaatcgagt gtttcccgac aacaaccgga
    29581 tggagaaaaa ttgccttgct gccagataca cgaacaaaac agttactacc gcaatcattt
    29641 cgtacagtaa atcttttttc cgaaaaacgg taagcatcat gaagtaagcc atcaaagaaa
    29701 gaaagggtgc gtaccaatag tcgtaatcca cggtcaatgt aataaataaa tagatcagca
    29761 acattatgag aaaaaaagct gtcttttctg gcaaataata aagtttacct tgggatagat
    29821 ggaagaattc ctctgtaact gacgaaaaaa actgtaagat ccataatatg gaaaatgtct
    29881 tcgaaggaaa atataaaaac aaacaaccta tcattactgg caaagaaagc agcaaacgta
    29941 cccatttttt aggaatacag cagacaataa ggcataggac accaatagtt aggataagaa
    30001 ggtagctgtt ttgcaattga ttagctacta caaatatcgg agcacctaca cttagtatca
    30061 caaaggagta aacgccacgc agccattttt cccgtttaat cgtcaatcca ttcacctcct
    30121 ggcaatgaac atatcttgtc tttttcttgg accatgagtt gtttttctac gaaataaaca
    30181 agataagccg ttcgatcttt tgacaatgtt tcaatagctt ctgagacttc aggagaattc
    30241 tcaggaacaa agaggacgat ttgttttttt gcatattttt tcaagtgtgc gaaaaaagct
    30301 ttctcatcgc cagcttccaa agaagcaaaa taggtatgac cggggtcttt gccatgaaag
    30361 gcgcggttgc ctaatatcag aagttccggc tgcttttctt ttctcaaatg ccataaagaa
    30421 aaatacaagt ctagcagagg ttcaaatttt ggactgggcg aaccccaaaa gcaaaaaaga
    30481 ggagaacatt cttcttcttg ataatcgtat tcacggtata accactcttg agtatgagca
    30541 gacaatttcc aatcgattcg gttgaaagaa tcacctggac gataagcgcg atgttcccga
    30601 aaatcaagac ctctttggta cgcgttcagc tgctgttttt tttccagaac tctctgtaat
    30661 ttttctgctt gaatcttaca aaaagcaggc agaacagtca caggaaaaga gatctctctt
    30721 tttgcacttt ttctgaaaag tcctagacta tcataggctg taaaaatgac agttaatgtt
    30781 tcatggcatc ctctttcttt tggctgccaa agcaattgga cttcttgcgg tttatttgta
    30841 agaatcaaaa tctcttgttt ttttctgcaa agattgctgg gaagccgatt tgtaaacgag
    30901 ggagaggtaa agaaaaagtt ctcttttttg ctatggaaaa aataacctgc atactttttt
    30961 tgcgataaac gagtggctgc aatgtacaag taaccgaaag tttctttaga aagctgctta
    31021 atgaaatcaa gctccatgat acataaagag taaaaaaggc caacaagaac cagcctaaag
    31081 aattgttgaa tacaagagca aaaagcacaa tgatgaaata taccagaaat aacacaaaat
    31141 taatgaaata atctttgatt ttttccattg tctacctcaa tctacctcac aggaatagga
    31201 atttgtgcaa caagagtatg aatgatttgt ttcttttcgt cttccttcaa tgaacgatcg
    31261 taaaaaatca ggcgatggga aaacacgtaa ggaactaaat cctgcaaatc tttgggcgtg
    31321 acgtaatttc tcccatggat taaagcataa gcttttgctg cctgaataaa ggaaaggctt
    31381 cctcgtggac tgatgccaag ctggatggca gcatgacttc ttgttgctga cactaactgc
    31441 aaggcataag atgccacttc gggactgaca aagacattcg ccacatttgt ttttatttct
    31501 tctatttcat aactgttcaa tacttcattt aagttatcca acactttttc gaatttatcc
    31561 aaaagtagca aaagttcgtc atcaaaagaa ggataaccga tttgtagtcg gaataaaaaa
    31621 cgatcgagct gtgcttccgg caaaggatat gttccttcgt actcgattgg attttgcgta
    31681 gctaagacaa aaaaatgatt gtctagaggg tatgtattgt tgtcgatcgt tgcatgattc
    31741 tcggccattg cttctaaaag tgctgactga gtacgaggag tcgtacgatt gatctcatct
    31801 gccaacaaga tcgtggtaaa gatcggtccc ggacgaaatt caaactcttt tgattgtgaa
    31861 ttgtatacgg aaaaaccaag aatatcacta ggcagcagat caggagtaca ttggactctg
    31921 ctgaaggttc cctgtacagc ttttgctagt gctttgacca gtaacgtttt acctacaccg
    31981 ggaatatctt cgaataagac atgaccacct gctaataggg ccacgatcat caattggata
    32041 gttgaacgtt tgccgatgac cgctttttct aattcttata tcaactgatc gattttttgt
    32101 ttggattctt ctattttttc ttccattttc acatcacctt ctcataaaat cgctatttat
    32161 ttcattgtaa tggaagggaa tacatcctac aagcaaagtg atcttattat gtttttttaa
    32221 agtacattcg ttttgaaatg agaatacgat taaattgagt aaaataaaaa ataatgagga
    32281 agatttgcgt atttaaataa atagaaaggg agttttttat ctttttagga gtgaactcat
    32341 tttgatcaaa caatatgttt agaaatcagg tgagaaatga tcgatgagat ggcaaaaact
    32401 attatcaaaa aatgcacaga atttattttc actaatcaat ctaatgaaag atttgatctg
    32461 gcgaaaagct gatttagctg aagaactgaa aatcgatgtt aaaacagtgg atcggcatct
    32521 gaaacgtttg gcggaaagcg actgtcccat tcagctgatt cttcataaga aaaccgttca
    32581 gttagtttat gatcaaggat atagcgaacc ttatctcttg tttgtttttc tgatccaatc
    32641 acccccgttt tgtttactga aaaatctgct attaaatgaa ccttacgagc agaagtacga
    32701 tcgttctacg caagagcgat tgagaaagtg gtttggcgag taccaccttt ctttttctta
    32761 taaaaaagca cagatctttg gttcagaaag aaaagtaaga tatctgctgt tttacttttt
    32821 gaaagatttt ccgcattttt ttgcagatga tggagagcag tccttttctg agatgttcat
    32881 ccaattattg aagcaaagaa aggatccggc agaaatcgag attttaggag acagtcgaac
    32941 actattcttt gaattgtttc ctgaattgct atttagagag gagcagattt tgccaataaa
    33001 agaaaaaaat tatctagcaa ttttgcgctt gagctgtaac cagattactg aaaagcggtg
    33061 gaaacggata gaagagacac aagactatcg gaaattgacg attgtgactg aaaagcttga
    33121 ttcgctgttt tggctgaata gcgaatttga gagcgaaagc aaatcaaagc tgataaaagt
    33181 actttaccaa gaatggcttc gttacgtaat tggtatccat gaccggctga tagaagaagt
    33241 tcgttattat caggaaacat tagaaaaatt tcccaattcc aaagataaac tatatcaatt
    33301 tcggctagcg atccaacaag cacttgcaca ccccgcagta gagtggggga tgcttttact
    33361 gaaaacactc caggaacgag ggtatttaga tgtccaccct cctgaagtga aaatcgtctt
    33421 tttttttcgc tatgaacacc aagaagcaag aagacttgct ggggtactga acaaaacgct
    33481 aagacatcga aaacggatct ctatacatgt atgtactcga aataagccgc ctcggtatgc
    33541 agatctagtg atcaccgatc atttttttcc actagaccat aacgaagatc aaaaaacgta
    33601 tctgtaccat ccttcatttg gtatcgaaag acttcttacc gatatcaatt actggttagg
    33661 caaaaaccga taaaaccttt ggaaaaaaga tcaaaacaag tcagtctgtg ctataataaa
    33721 aagcgattag taaaggagga aatccattgg aattaaagaa attagaagtt cccacatctt
    33781 cgatcacaga agtgaaacga tcgccgatgg atgtatttgc tcaagcgcga gacgcgggaa
    33841 ctggcgtata tatatttaat cgtgaaaaag tagctggcgt gatgctgacc caagaacaat
    33901 acaaaacgct cttgcaagaa ctagatgtcc ttcgtcaaac agtgaaagtg gagaggaaag
    33961 aaccaaaaga aataaacgaa gaacctatta acaaaacagc ttccgtcgta tccaatgctg
    34021 aagggatgga agagctggcc caaacattac agcactcgct cattactggt gtgacgatta
    34081 cagcaaaaaa tctagatgaa cgaatggtag cactaggttt tattacgaaa aagaccggat
    34141 ttggcggagt cgtggatatg cttagcgagt tgatggaaac tgggaaaatc aactaccagt
    34201 taagaagaaa accgcaaaat cggacaatca tagctgaaat cataggagag caaaacagtc
    34261 aatctcaatt gatggataaa atcatcatca agaaaatttt tctacatgag ctataagaaa
    34321 accatgttcg cacttctagg caagccaggc tttgaagacc ttgccaaaga attgaacgaa
    34381 cgcctttaag ataagggttt ttcgctagat ttaaaaaatc agtgatagaa acatgttcgc
    34441 ttataaataa aattagtgat agttttagtg atagtgagct taaaaaagca ctcaatttga
    34501 gtgctttttt atttgctctt ctatatagtt ttctagttga ttcattgatc tttttttcac
    34561 ttcgggagaa atatgggcat agacttgtgt agtggaaaca tctttatgac ctaaaaaatc
    34621 tttgatatct tctaaaggta ttcctgcttg tctcgttcta gctgaaaaag caaaacataa
    34681 tgttggtgtt ttcctttcag catatctatc agcaagatgt agagtaggac aacctcgtga
    34741 gccaaaagtc ctgtgcaaat cgagttacaa cacacacatg ataaagaaac ttttgaaaag
    34801 aactataaag tatacgttga attggcaaga gattcagcaa tgaaatatgg tattccatta
    34861 acattagaca ctccttataa ccaaccagga atcaaatcgc atttatgggt aacacaaaat
    34921 atttggggcg atcatacaga tccttacggt tatctttctg aaatgggtgt aagtaaagaa
    34981 aaactagcct atgatttggc tcatggtttt acggatgata atccaactac ttcggaggat
    35041 aaaccagtaa ttgatccaac tcgagcaggt gctgcaaatt ctacgctgac agatggaaca
    35101 aattacgccc acattgatca gttcggagaa atcgaaaacg caaacttgca tgtagctgga
    35161 tggcacattg ctaattataa atacgagtat attttcatta tggactacaa tactggaaaa
    35221 gaactagcta gagtaagagc tgatgggatt tatagaccag acgtaaatca agcttataat
    35281 actttaggaa atgttggcta tcatgtatct ttcaatatgc gtgatttccc taataagaaa
    35341 gtatacgtca tgatgcgtgc gacaaacgat ccagaaggaa atactaaggg tggagcacaa
    35401 gattttcatg acaagcgttg gtatttaaat attccacaac gataaaaaat ccccccctct
    35461 tt
//
LOCUS       DACGLI010000030        34789 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.031, whole genome shotgun sequence.
ACCESSION   DACGLI010000030 DACGLI010000000
VERSION     DACGLI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.031"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(233..1081)
                     /locus_tag="IXT22_001554"
     CDS             complement(233..1081)
                     /locus_tag="IXT22_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4862923.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="IXT22_001555"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="IXT22_001555"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAQ4862924.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="IXT22_001556"
     CDS             complement(3582..3761)
                     /locus_tag="IXT22_001556"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAQ4862925.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="IXT22_001557"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="IXT22_001557"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4862926.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="IXT22_001558"
     CDS             5909..8188
                     /locus_tag="IXT22_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4862927.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="IXT22_001559"
     CDS             complement(8281..8928)
                     /locus_tag="IXT22_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862928.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="IXT22_001560"
     CDS             complement(9107..9826)
                     /locus_tag="IXT22_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4862929.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="IXT22_001561"
     CDS             complement(9957..11108)
                     /locus_tag="IXT22_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4862930.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="IXT22_001562"
     CDS             complement(11325..12065)
                     /locus_tag="IXT22_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4862931.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="IXT22_001563"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="IXT22_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAQ4862932.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /locus_tag="IXT22_001564"
     CDS             complement(12449..13042)
                     /locus_tag="IXT22_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4862933.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13673)
                     /locus_tag="IXT22_001565"
     CDS             complement(13026..13673)
                     /locus_tag="IXT22_001565"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAQ4862934.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="IXT22_001566"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="IXT22_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAQ4862935.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="IXT22_001567"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="IXT22_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAQ4862936.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="IXT22_001568"
     CDS             complement(15119..15646)
                     /locus_tag="IXT22_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAQ4862937.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="IXT22_001569"
     CDS             complement(15826..16611)
                     /locus_tag="IXT22_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAQ4862938.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /locus_tag="IXT22_001570"
     CDS             complement(16604..17473)
                     /locus_tag="IXT22_001570"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAQ4862939.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="IXT22_001571"
     CDS             complement(17474..18853)
                     /locus_tag="IXT22_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAQ4862940.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="IXT22_001572"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="IXT22_001572"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4862941.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="IXT22_001573"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="IXT22_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAQ4862942.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="IXT22_001574"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="IXT22_001574"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAQ4862943.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="IXT22_001575"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="IXT22_001575"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAQ4862944.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="IXT22_001576"
     CDS             complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="IXT22_001576"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4862945.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22811..23035)
                     /locus_tag="IXT22_001577"
     CDS             complement(22811..23035)
                     /locus_tag="IXT22_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4862946.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23088..24050)
                     /locus_tag="IXT22_001578"
     CDS             complement(23088..24050)
                     /locus_tag="IXT22_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAQ4862947.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24060..24500)
                     /locus_tag="IXT22_001579"
     CDS             complement(24060..24500)
                     /locus_tag="IXT22_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4862948.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24806..25771
                     /locus_tag="IXT22_001580"
     CDS             24806..25771
                     /locus_tag="IXT22_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4862949.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25828..26058)
                     /locus_tag="IXT22_001581"
     CDS             complement(25828..26058)
                     /locus_tag="IXT22_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAQ4862950.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26144..27031)
                     /locus_tag="IXT22_001582"
     CDS             complement(26144..27031)
                     /locus_tag="IXT22_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAQ4862951.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27120..28343)
                     /locus_tag="IXT22_001583"
     CDS             complement(27120..28343)
                     /locus_tag="IXT22_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4862952.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28360..29439)
                     /locus_tag="IXT22_001584"
     CDS             complement(28360..29439)
                     /locus_tag="IXT22_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4862953.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="IXT22_001585"
     CDS             complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="IXT22_001585"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAQ4862954.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRGLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(31297..31563)
                     /locus_tag="IXT22_001586"
     CDS             complement(31297..31563)
                     /locus_tag="IXT22_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAQ4862955.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32042..34276
                     /locus_tag="IXT22_001587"
     CDS             32042..34276
                     /locus_tag="IXT22_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4862956.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34424..34744
                     /locus_tag="IXT22_001588"
     CDS             34424..34744
                     /locus_tag="IXT22_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4862957.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPQH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9843 a         7511 c         6063 g        11372 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    22381 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    22441 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    22501 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    22561 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    22621 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    22681 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    22741 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    22801 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    22861 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    22921 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    22981 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    23041 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    23101 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    23161 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    23221 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    23281 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    23341 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    23401 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    23461 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    23521 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    23581 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    23641 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    23701 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    23761 ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa
    23821 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    23881 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    23941 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    24001 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    24061 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    24121 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    24181 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    24241 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    24301 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    24361 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    24421 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    24481 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    24541 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    24601 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    24661 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    24721 aacagaacta tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt
    24781 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    24841 gccgggtgtc tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa
    24901 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    24961 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    25021 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    25081 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    25141 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    25201 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    25261 gcgagtccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    25321 agggctgttt caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca
    25381 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    25441 tacttatttt attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac
    25501 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    25561 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    25621 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    25681 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    25741 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    25801 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    25861 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    25921 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    25981 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    26041 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    26101 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    26161 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    26221 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    26281 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    26341 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    26401 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    26461 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    26521 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    26581 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    26641 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    26701 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    26761 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    26821 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    26881 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    26941 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    27001 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    27061 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    27121 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    27181 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    27241 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    27301 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    27361 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    27421 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    27481 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    27541 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    27601 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    27661 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    27721 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    27781 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    27841 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    27901 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    27961 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    28021 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    28081 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    28141 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    28201 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    28261 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    28321 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    28381 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    28441 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    28501 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    28561 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    28621 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    28681 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    28741 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    28801 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    28861 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    28921 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    28981 gtgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata
    29041 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    29101 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatccga taaaggaatt
    29161 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    29221 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    29281 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    29341 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    29401 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    29461 acttaagccc tatttttgtc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    29521 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    29581 attcatgaac aagttcaacg acttcttcca tcgtatcgca ttctttcaat gcacgatcag
    29641 caagttcagc cattttcgct gtgtccaagc gtttcattaa accacgcgtt ttaagaatag
    29701 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    29761 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    29821 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    29881 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    29941 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    30001 tgatgccgac ttggatcgta tcagatactt ccttgccttc acttatcaat ttttgttttt
    30061 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    30121 tgatacgtaa attaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    30181 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    30241 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    30301 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    30361 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    30421 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    30481 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    30541 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    30601 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    30661 tagcagtaat ttcttttgtc ccaacgattg ctggaatttc taaagaacgt gccatgatag
    30721 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    30781 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    30841 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacgtcac
    30901 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    30961 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    31021 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    31081 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    31141 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    31201 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    31261 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    31321 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    31381 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    31441 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    31501 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    31561 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    31621 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    31681 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    31741 tttcatcctt ttcttcacat tttataacaa acgtgtttat ttcctttttc ttgtcgcttt
    31801 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    31861 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    31921 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    31981 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    32041 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    32101 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    32161 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    32221 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    32281 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    32341 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    32401 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    32461 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    32521 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    32581 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    32641 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    32701 agttcacgaa atagtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    32761 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    32821 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    32881 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    32941 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    33001 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    33061 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    33121 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    33181 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    33241 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    33301 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    33361 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    33421 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    33481 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    33541 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    33601 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    33661 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    33721 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    33781 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    33841 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    33901 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    33961 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    34021 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    34081 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    34141 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    34201 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    34261 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    34321 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    34381 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    34441 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    34501 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctc aacataatga
    34561 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    34621 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    34681 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    34741 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaa
//
LOCUS       DACGLI010000031        34501 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.032, whole genome shotgun sequence.
ACCESSION   DACGLI010000031 DACGLI010000000
VERSION     DACGLI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.032"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            214..498
                     /locus_tag="IXT22_001589"
     CDS             214..498
                     /locus_tag="IXT22_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAQ4862958.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="IXT22_001590"
     CDS             complement(779..1198)
                     /locus_tag="IXT22_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAQ4862959.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="IXT22_001591"
     CDS             complement(1200..1784)
                     /locus_tag="IXT22_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAQ4862960.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="IXT22_001592"
     CDS             complement(1831..3306)
                     /locus_tag="IXT22_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAQ4862961.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="IXT22_001593"
     CDS             3487..3798
                     /locus_tag="IXT22_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4862962.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="IXT22_001594"
     CDS             complement(3913..6249)
                     /locus_tag="IXT22_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4862963.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="IXT22_001595"
     CDS             6391..7059
                     /locus_tag="IXT22_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862964.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="IXT22_001596"
     CDS             7062..8105
                     /locus_tag="IXT22_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4862965.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="IXT22_001597"
     CDS             complement(8342..9223)
                     /locus_tag="IXT22_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4862966.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERALRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="IXT22_001598"
     CDS             9382..10110
                     /locus_tag="IXT22_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAQ4862967.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKSCGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="IXT22_001599"
     CDS             10266..10583
                     /locus_tag="IXT22_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4862968.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="IXT22_001600"
     CDS             10576..11184
                     /locus_tag="IXT22_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAQ4862969.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11200..12030
                     /locus_tag="IXT22_001601"
     CDS             11200..12030
                     /locus_tag="IXT22_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAQ4862970.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            12168..12656
                     /locus_tag="IXT22_001602"
     CDS             12168..12656
                     /locus_tag="IXT22_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAQ4862971.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="IXT22_001603"
     CDS             12707..13579
                     /locus_tag="IXT22_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAQ4862972.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="IXT22_001604"
     CDS             13755..14117
                     /locus_tag="IXT22_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4862973.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYIQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="IXT22_001605"
     CDS             14126..14878
                     /locus_tag="IXT22_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862974.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="IXT22_001606"
     CDS             14892..16694
                     /locus_tag="IXT22_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4862975.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="IXT22_001607"
     CDS             16971..18011
                     /locus_tag="IXT22_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4862976.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="IXT22_001608"
     CDS             complement(18063..20207)
                     /locus_tag="IXT22_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4862977.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="IXT22_001609"
     CDS             complement(20564..21937)
                     /locus_tag="IXT22_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4862978.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="IXT22_001610"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="IXT22_001610"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAQ4862979.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="IXT22_001611"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="IXT22_001611"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAQ4862980.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="IXT22_001612"
     CDS             complement(23385..24398)
                     /locus_tag="IXT22_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4862981.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25081)
                     /locus_tag="IXT22_001613"
     CDS             complement(24479..25081)
                     /locus_tag="IXT22_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4862982.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITNYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25266..25967
                     /locus_tag="IXT22_001614"
     CDS             25266..25967
                     /locus_tag="IXT22_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4862983.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25977..28688
                     /locus_tag="IXT22_001615"
     CDS             25977..28688
                     /locus_tag="IXT22_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4862984.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANIGNGSVDYFVYLPESAFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29034..30662
                     /gene="treC"
                     /locus_tag="IXT22_001616"
     CDS             29034..30662
                     /gene="treC"
                     /locus_tag="IXT22_001616"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAQ4862985.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30722..31903)
                     /locus_tag="IXT22_001617"
     CDS             complement(30722..31903)
                     /locus_tag="IXT22_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4862986.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32155..33678
                     /locus_tag="IXT22_001618"
     CDS             32155..33678
                     /locus_tag="IXT22_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4862987.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33747..34475)
                     /locus_tag="IXT22_001619"
     CDS             complement(33747..34475)
                     /locus_tag="IXT22_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862988.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
BASE COUNT        10901 a         6177 c         7004 g        10419 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctaag ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaatctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatatacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaag gcacttggat tgtagtttgt gatagtcaac atattgtttg
    24781 tatctttcaa ggaatccttc aacaacaagt cagtgaattc tgccggagca gacaaagcag
    24841 atattcctcc agcatctgtc tgatgactta gataagagaa agtagtgatg tctacattca
    24901 ctaaaacttt caaggcagcg gtacgtttca atgtttttgc taacaaatca ttgtttgtca
    24961 gaatagattg tgcagtgtgt ggagagagtg taccgttatt tacgatccct ttttgcatgt
    25021 cgatcgcgac aaaagcagtt tttgataaat caaaaatcat attttccttt aaatcattca
    25081 tgatgttcct tctttcaaat aacaatgttt tttatgtaag taaatcataa atcgtttatt
    25141 tgtcaactaa ataaaggatt cctttcttta gtctagagaa attcagtggt aaaataaata
    25201 agtgtgagaa aacgcattcg atgcatagat atagcgagaa atatcgtgaa aatggaggaa
    25261 tcagagtgaa gtatgtcgaa gtaaaaaatg aatacaaacg atacaaaatg ggagaaacga
    25321 ccattacagc aaatgacgat atttcttttt caattgaaaa aggcgaatta gtgattatac
    25381 ttggtccaag tggagcagga aagtcaacga ttcttaatat tttaggtggg atggatacac
    25441 ctgatgaagg tcagatcatt attgatgaca cagatattgc gcaattttca gataaacagc
    25501 ttactgctta ccgacgaaca gatgtagggt tcgttttcca attctacaat ctcgttccta
    25561 atctaacagc aaaagaaaat gtggaattgg caacggaagt ttctcctgat gcgcttgatc
    25621 ctgtagaggt attgaggcaa gtgggcctag ctcatcgatt gaataacttt ccgtcccaat
    25681 tatcaggagg cgaacagcag agggtttcaa ttgctcgtgc actagctaaa aatcccaaac
    25741 ttcttttatg tgatgaaccg acaggcgcgc tggattttga aacgggcaag caagtattga
    25801 aattattgca aaacgctagc agacaacacg gcaataccgt tttgatcatt acacataatt
    25861 ctgctttagc gcccatcgct gatagagtca ttcacattaa tgatgctaaa gtaaggtctg
    25921 ttgaattaaa tgatcatcct tcatccattg atgagattgt atggtagggg gattttatga
    25981 aaacaagaac atatcttaaa gcaggttttc gcgaaattcg gcaatctaaa ggacgattca
    26041 ttgcaatcat ccttattgtc atgctaggaa cacttttatt tgtaggtgtc aaaactgctg
    26101 gacctgtcat gcaaaaaacg atggatcact atgttggtac agcaggactt tctgatttgc
    26161 aaatcgtttc tactggtggc ttgacacaaa aagatattgc tcaagcagaa aagatcccag
    26221 atgcaaaagt agaaacagga aaacagatct attattccaa tactggcaaa aacgaagtga
    26281 ttcaaatatt ttcttataac aaaaataaca agcagaacaa gctacaatta actgatggaa
    26341 aactcccgga aaaaccaaac cagcttgtat tggatgaaaa agcggaagat gaagggtata
    26401 aaatcggtga tatttatcag attgattcag atgaattgaa agaaaaagag tataccatca
    26461 cgggctttgt ccgttctcca ttgttcatca acaatttgga gagaggatac gcgaacatcg
    26521 gaaatggtag cgtcgattat tttgtctatt tgcctgaatc cgcttttaaa acagatattt
    26581 attctgtctt atatcttgat tttacaaacg taaagaattt gaatacgtac agcaaagctt
    26641 acaaagataa aatggagcaa aatcaagaaa aggcagaaaa gtatttacaa gatcgacccg
    26701 aagaacgctt agaagagctg aaaaaatcgg ccaacgaaga attagaacca gcacagcaaa
    26761 aaataacaga aggcaaagca caaatagcac agggaagaac acagttagaa gatgctaaaa
    26821 aacagttagc gcaacagtca gcagctatcc agcagcttcc tgaagcgcaa cgaacaatcg
    26881 ctgttcaaac attatctcaa caagaagctc aacttgctga acaagaaagg caattagttg
    26941 agaaagaacg tgaactggcc tctgcagagg aagaattgaa tcgaaatgca gaaaaaattg
    27001 aaaatttaac taaaccatca tacctataca atgaacgttc agaaaatgtc ggttttcaag
    27061 aatttggtga tctgtctgat cgtatcgctg cgattgctaa tgtttttcct gttttctttt
    27121 tctttattgc cgcattgatc acctttacga caatgacacg tatggtagaa gaaaaccgca
    27181 gggaaatcgg gacattaaag gcgttaggtt atacgaaagt tgaaatcgca aaaaaatatg
    27241 caatctatgc aagtctagcc tcagggatag gcattgtttt aggaacgata ttaggaacga
    27301 atcttttgcc aaggatcatt tttgagctgt ctaacgagcg gtatgatatt gggagtgcgc
    27361 ttatttttta tgactggccg ccgattttac aagcagctgc cgcattcttc attgccgcat
    27421 ttggcgctgc aatgatcgtt ttattcaaag atttaagaga acggcctgct gcattgcttc
    27481 aaccgaaagc accgaagcca gggaaacgca tttttcttga atacatcact ccgctgtggt
    27541 cacgccttag ctttaatcaa aaaatcagtt accgaaatct cttccgatat aagtcaagaa
    27601 tgcttatggc gattatcgga attgctggat gtgccgggct gatggttgca ggcgtgggat
    27661 taaaagattc tctaagttct gtctcagcca aacaatttgg accgatcatt gactatcaag
    27721 caatcgttac attggattca tccacggaag atagtcgtca aaaagcagcg gatatgctgc
    27781 agaagcaaga aaaagtaaat gagatcctag ctattcatac tcaaaccgta gaattgagaa
    27841 aaaaaggaca tgcttcgcaa agtctgacag tgatcgtacc aagtaaaaca gctgatttgg
    27901 atcgttttat ccatttaact gatcttgaag agaacccacg ctccttgcct aaaacaggaa
    27961 tcgctattac gcaaaaagca gcagaactat ttgacttatc tacaggagat catatttcgc
    28021 tttatgatga agatcaaaaa gaatggaaag tcgaagtaaa agaaatcgtg aaaaactatc
    28081 taggtagctt tatttatatg tcccctgaat attatgcttc agttactgat caatcgatga
    28141 tggataatgc atttttgctg cgtacagata agatgacaac gaaagaagaa gaaatgcttt
    28201 ccgagaaact gcttgccaca gacgctgtga caaatacgtc tttcatgtcc aaacaaatcg
    28261 aaacgcaaga agaatcaatg gcgaacttag actcggttgt cttaatcttt gtcgtattat
    28321 caggactgct ggcttttatc gtcttgtata atctaactaa tatcaatatt tccgagcgtg
    28381 tacgcgaatt atctacaata aaagtccttg gattttttga taaagaagtc acgatgtaca
    28441 ttgttcgaga aaatatcatc tttactcttt taggaatcat cggaggattt ggtgtaggat
    28501 atatattgac tgacttcatc ttgcaacaag cgtctatgga gaatgtcatc tttccattag
    28561 tgatcacatg gtgggcttat gtcttatcag caggattaac tatcgtattc acggttattg
    28621 tgatgatcgt tacccatttc aaattaaagc atatcgatat gattgatgcg ttgaaatcga
    28681 atgaataaaa acagaggttg tgaaatcagc ggttgtgaaa aagctgtcct gcatcgagca
    28741 aaaagaatac tcaaataaaa ttagctcctc atgttttaca tttgagaaga ctgattgccg
    28801 tagataaaag cttttgaaca ccatttatag aagaaacaag aatattttgc tattttaaac
    28861 aagaggatag acaaatacat gtctgatctc ttgtttttta ttgggcaaca gacctcttag
    28921 aatgtataaa gataaatttt acaaacgctt tcggttcagt tataataata aatgataact
    28981 tgtatatata agttgtggta ggtaataaat cagttgaatg gaggtaaata tccatgacat
    29041 ttaaagacaa agtcatttac caaatctatc ccaaatctta caaagacagt aatggtgatg
    29101 gaattggaga tttaaaagga atcaaagaaa aactcccgta tctgaatgat ctaggcatcg
    29161 acatgatttg gctaaaccct atttatccaa gccctcaaaa agacaacggt tatgatatct
    29221 ctgattacac agccatcgat cctatctttg gtacgatgga ggaattcgaa cagctaatag
    29281 ccgaagcaaa gaaataccgg atagaaatca tgctcgatat ggtgctgaat cacgtttcga
    29341 cagaacatga atggttcaaa aaagcactag caggggacca gcattatcag gacttcttca
    29401 ttttaagaga agagccaacg gattgggtat caaaatttgg tggaagtgct tggtcgccat
    29461 ttggagatac ggggaaatat tatttgcact tatatgatcg gacacaagct gacttgaact
    29521 ggcggaacca agcagtaaga gaggaactat tcaaagttgt tcgtttttgg atggaaaaag
    29581 gggtaaaagg attccgtttc gatgttatca atgttatcgg taaagacgaa caattgaaaa
    29641 ataataaaga aaatgatggc aaacctgaat atacggacaa accaatcacc catacgtatc
    29701 taaaagaatt gaaccaagca acgtttggga cggattccac tatcatcaca gtcggtgaaa
    29761 tgagctctac gacgatcgaa aattgtatct tgtatacaga acctagtaga gaagaattat
    29821 caatggtctt taatttccat catttgaaag tcgattatga aaatgggaat aaatggtcta
    29881 ctcctccatt tgattttgca gaattaaagc gactatttca tacatgggga gaaaagatga
    29941 gtgagggtaa cggctggaat gctctatttt ttaataatca tgatcagcca cgtgcgctca
    30001 atcgatttgt agctatcgat cagtatcgaa aacaaggagc agagatgcta gcaaccatga
    30061 tccatttgaa ccgtgggacg ccctatattt atatgggaga agaaatcggc atgatcgacc
    30121 cagactattc atcgatttcc gactatattg acgtagaaag tttgaatgct tataagttac
    30181 tccttgaaca aggattcaca gaaaaagaag cgtttcgtcg gatcaaagca aaatctcgcg
    30241 ataactctcg aacacccatg caatggtcag acacagaaca agcaggattt actacaggga
    30301 aaccttggtt aaaagttgga ggcaagctag aagagattaa tgtagaaaaa gaactatctt
    30361 ctgaagattc tattttgtcc tattacaaga aattgattcg gctgagaaaa acatatccaa
    30421 tcgttgcaca aggagattat catgcttatg aagcaaatca tccggaagtt tatggctttc
    30481 ttcgccaatt tgaaggacag cagctgcttg tattaacaaa tttctatgat aaagatacaa
    30541 ggatcgccat cccagaagga ttcacagaag ccaatattct tatcgataat tattccgata
    30601 ctgttcttca tcaaagtctg gagctaaaac cataccaggc aattgctttg ctgaaaaatt
    30661 aaaacaaaaa cacaaaacgt cgttcctacg agctattctc gtaagatcga cgttttgtgt
    30721 tttatttaaa ataatcttct tcagaaaatg aagagttttc atactctcct ttatcgccat
    30781 aaaatttatt gtagcgttgt ttgaatttac ggaaaataaa agtaacgagt aatttgacta
    30841 acgtatagat aggaatacca aaaataacgc ccacaattcc cattagatca cccatgacaa
    30901 gtaaaacgat taagatcgta atcggatgga tctgtaaacg atcacccatt actcgaggaa
    30961 tcaccaagtc accgtggaga agttgtacgg caaaccagac aatgacaaat ttgacagcca
    31021 taaaagtaga gtcttggaat gcaatgatca aacctggaaa gaaggcgata aacggcccaa
    31081 tatatggaat gatacataac aacccagcag aaatagctaa aacactagca aattctaatc
    31141 cgatcagtaa gaaacaaacc cagtagactg ctccaaggat aaatgaagca atgatttgcc
    31201 cctttagaaa tgaacccaat tgttgattag caatctttgt caaattttta aaatctgtac
    31261 gaaatgctgg tgggacaatc gctaaaactg actgataaaa tttttgagga tctctcaaaa
    31321 ggaaaaaagc gacaattgga ccagtaaata aagtaataaa aatagctgta acagttgaaa
    31381 aaatgttgct gatccgttgt gcgccacttt cccaataatt tccaataaat ccagctatat
    31441 cagacgtcac gtcgtcaata gaagcgaaaa attgattaaa tgaatcggca aaaggtgttt
    31501 tctccaaaaa ttgtcggaga ctctcttgaa aatcttgaaa caaatctggc aaactactga
    31561 tcaatgtctt tgcctgttct tcaagaaaag gaataagcca tatgcttcca agccccaata
    31621 aaaataaaat aatcacataa acgataatga ctgacaagtt cctcgaaagg tgcttgctca
    31681 aacgtttgat gactggttcc aaaagataat acaagatcag tgcaaacaat aatgggggca
    31741 agatagtagc gataatgatt ccgacaggct tgaatataaa cgagatctga tggaaaaaat
    31801 aaatgatcag cgcaagtaag ataactattc ctaaaacata gtaagaggtt tttcctccta
    31861 aaaagcggat caaacgattc gttgtatctg tttctttttt cactcttttt cctcctttat
    31921 ctataacttc attatagaca aaagcgggta taaaaggaaa atgatagagg ttgattgcaa
    31981 aaatatcgtc aatcattcat ataaactttc tcatcaatta aaataagaaa acgcttgaca
    32041 gttcttttaa ccatatgata aattaaatcc tgttgctaaa acgtaactat tacggtttgc
    32101 gaaaagcgaa tcggaacatt caaatgaaag aagatgagaa gaggagtgtc ataaatgaaa
    32161 cgattgatag gtatattggc catgctggtt ttagcaggta tgttaactgc ttgcggggca
    32221 agtgggaaag ccgaggacag taaagaaaaa ttgagcgtga tgacgacctt ttatcccatg
    32281 tatgatttta caaaagcaat cgtcggggat gaaggagaag tagagttatt gattccagca
    32341 gggactgatt cccacgatta tgaaccttct gctaaagaca tggcaaagat ccaagataca
    32401 gatatctttg tttataatga tgaaaacatg gaaacatggg tccccgcaat ccaaaaaaca
    32461 ttacaagaag gcaatgtcca tacgataaaa gcgacagaag gtatgctttt acttccggga
    32521 agtgaagaag gacatgatca tgaccatgaa cacggggaag aaggccatac acatgagcta
    32581 gacccacatg tatggctagc tccaagttta gcaatcaagc aggtagcaaa catacgtgat
    32641 cagctgattg aagcttaccc agaaaaacag gaagtatgga caaaaaatgc agcagcctat
    32701 accgagaaac ttcaagcact ccatcagctt tatcaagaaa cctttaagca agcaaaacaa
    32761 agatcttttg tcacgcaaca tgctgcattc aactatctag cgttagaata tggattgaat
    32821 caagtatcga ttgctggtct ttcttctagt gaagaaccgt ctgcggcgag aattgctgaa
    32881 ctgaaacact ttgttaaaga acatggaatc aactatattt attttgaaga aaacgccaaa
    32941 gatagtattg ccagaacgtt agcaaacgaa gcaggtgtat ctttagaagt attgaatcct
    33001 ttggaaggat tgacgaatga acaaatagaa aatggagaaa actatctttc tatcatggaa
    33061 gcaaacctcg aagcgttgaa aaaaacgaca gagacagaaa acccgctaga agatactttg
    33121 acccccaaaa aagaaaagag cgtctacaac ggttattttg aagacgagga tgtacaagat
    33181 cgctctcttt cagattgggc aggaacttgg caaacagtag atacgtatgt agaagatggg
    33241 acttttgatc ctgtttttga atataaagaa aaattgaatc aggataagac agcacaagaa
    33301 tataaagaat attatacgaa gggctatcaa acagatattg cttcaatcaa gatcagtgag
    33361 aaagagatgg catttacgtt taagaatgga acaacgaaac gttcaaatta tcgttatgta
    33421 gggaaagaaa tcttgaccta cgaggcagga aaccgtggcg taaggtatct attcgaagca
    33481 gaagataagg aaagtggcgc ttttagatat attcaattca gtgatcacac gattgcaccg
    33541 gctgactccg aacattttca tttatatgca ggaaatgaaa gtcaagaagt attgctgaaa
    33601 gaaatggaga attggccaac attttatcca gatacaatgg atggacgtga aattgcacag
    33661 gaaatgcttt tgcactgata ggcaaaaaag aaccgaaggg tttggatcgg ctggtcattt
    33721 agtcggtcca aactattcgg ttctttttat gaaatcaatt tctttaatcc acggatagag
    33781 gctgggatgg tctcgccgtt tgccaacgtg acttctctgg tttttttatt aatcgaccgc
    33841 acattttgtg tattgataac ataggattta tgacaacgga taaaattccg atgcattttc
    33901 tcgatttctt tgatcttctc atagaattgt aattgggcat gagtcaaatg gacttccagt
    33961 ttatgtggcg ctcctagcga agtagaaaaa tattggatgt ctttgatcgg taaaaatttg
    34021 atctcatcat taaactctat tttgaagata tctttttgga tttgggacat ttgaaaatct
    34081 tcgaaaattt tgctcaggat atgctcgaca ttttctttta aatcataaag atcttctttg
    34141 acgatataat cagtcggttc gatgttgctt tttaagattt tcatcgacat ttccgtatgg
    34201 gaagtcacat agattatttt tcctaaagga tctaattcac ggatcaattt accgatcgct
    34261 acaccatcca tttcactgtc ttctagttcg atatctaaaa agtaaatacc aaaagaagaa
    34321 gttctgatct tggctgcatt gagaagttct tccggatcag aggtagaaat atggacataa
    34381 ctgtctaagt tttcaatcat gattctattt ttgatcaccg ttgataaaac ttctaattgt
    34441 tttggatcgt cttcacaaat ataaatggga atcatatcat tactccttta ttttatttgt
    34501 a
//
LOCUS       DACGLI010000032        34495 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.033, whole genome shotgun sequence.
ACCESSION   DACGLI010000032 DACGLI010000000
VERSION     DACGLI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.033"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            399..1088
                     /locus_tag="IXT22_001620"
     CDS             399..1088
                     /locus_tag="IXT22_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4862989.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1075..2283
                     /locus_tag="IXT22_001621"
     CDS             1075..2283
                     /locus_tag="IXT22_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4862990.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2577..3848
                     /gene="serS"
                     /locus_tag="IXT22_001622"
     CDS             2577..3848
                     /gene="serS"
                     /locus_tag="IXT22_001622"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAQ4862991.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4397..5881)
                     /gene="guaB"
                     /locus_tag="IXT22_001623"
     CDS             complement(4397..5881)
                     /gene="guaB"
                     /locus_tag="IXT22_001623"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAQ4862992.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6386..7081)
                     /locus_tag="IXT22_001624"
     CDS             complement(6386..7081)
                     /locus_tag="IXT22_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAQ4862993.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7171..8271)
                     /gene="ychF"
                     /locus_tag="IXT22_001625"
     CDS             complement(7171..8271)
                     /gene="ychF"
                     /locus_tag="IXT22_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAQ4862994.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8280..8471)
                     /locus_tag="IXT22_001626"
     CDS             complement(8280..8471)
                     /locus_tag="IXT22_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAQ4862995.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8492..9382)
                     /locus_tag="IXT22_001627"
     CDS             complement(8492..9382)
                     /locus_tag="IXT22_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAQ4862996.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9369..10136)
                     /locus_tag="IXT22_001628"
     CDS             complement(9369..10136)
                     /locus_tag="IXT22_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4862997.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10148..10861)
                     /gene="rsmG"
                     /locus_tag="IXT22_001629"
     CDS             complement(10148..10861)
                     /gene="rsmG"
                     /locus_tag="IXT22_001629"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAQ4862998.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11093..12994)
                     /gene="mnmG"
                     /locus_tag="IXT22_001630"
     CDS             complement(11093..12994)
                     /gene="mnmG"
                     /locus_tag="IXT22_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAQ4862999.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13011..14408)
                     /gene="mnmE"
                     /locus_tag="IXT22_001631"
     CDS             complement(13011..14408)
                     /gene="mnmE"
                     /locus_tag="IXT22_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAQ4863000.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14752..15090
                     /locus_tag="IXT22_001632"
     CDS             14752..15090
                     /locus_tag="IXT22_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863001.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15258..16016)
                     /locus_tag="IXT22_001633"
     CDS             complement(15258..16016)
                     /locus_tag="IXT22_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4863002.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16034..16852)
                     /locus_tag="IXT22_001634"
     CDS             complement(16034..16852)
                     /locus_tag="IXT22_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4863003.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16849..17205)
                     /gene="rnpA"
                     /locus_tag="IXT22_001635"
     CDS             complement(16849..17205)
                     /gene="rnpA"
                     /locus_tag="IXT22_001635"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAQ4863004.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17323..17457)
                     /gene="rpmH"
                     /locus_tag="IXT22_001636"
     CDS             complement(17323..17457)
                     /gene="rpmH"
                     /locus_tag="IXT22_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAQ4863005.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17980..19314
                     /gene="dnaA"
                     /locus_tag="IXT22_001637"
     CDS             17980..19314
                     /gene="dnaA"
                     /locus_tag="IXT22_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAQ4863006.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19512..20642
                     /gene="dnaN"
                     /locus_tag="IXT22_001638"
     CDS             19512..20642
                     /gene="dnaN"
                     /locus_tag="IXT22_001638"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAQ4863007.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20871..21113
                     /gene="yaaA"
                     /locus_tag="IXT22_001639"
     CDS             20871..21113
                     /gene="yaaA"
                     /locus_tag="IXT22_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAQ4863008.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21100..22224
                     /gene="recF"
                     /locus_tag="IXT22_001640"
     CDS             21100..22224
                     /gene="recF"
                     /locus_tag="IXT22_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAQ4863009.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22221..24167
                     /gene="gyrB"
                     /locus_tag="IXT22_001641"
     CDS             22221..24167
                     /gene="gyrB"
                     /locus_tag="IXT22_001641"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAQ4863010.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24187..26658
                     /gene="gyrA"
                     /locus_tag="IXT22_001642"
     CDS             24187..26658
                     /gene="gyrA"
                     /locus_tag="IXT22_001642"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAQ4863011.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26894..27193
                     /locus_tag="IXT22_001643"
     CDS             26894..27193
                     /locus_tag="IXT22_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAQ4863012.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27243..27755
                     /gene="ssb"
                     /locus_tag="IXT22_001644"
     CDS             27243..27755
                     /gene="ssb"
                     /locus_tag="IXT22_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4863013.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27781..28017
                     /gene="rpsR"
                     /locus_tag="IXT22_001645"
     CDS             27781..28017
                     /gene="rpsR"
                     /locus_tag="IXT22_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAQ4863014.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28160..30133
                     /locus_tag="IXT22_001646"
     CDS             28160..30133
                     /locus_tag="IXT22_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAQ4863015.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30139..30591
                     /gene="rplI"
                     /locus_tag="IXT22_001647"
     CDS             30139..30591
                     /gene="rplI"
                     /locus_tag="IXT22_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAQ4863016.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30865..32232
                     /gene="dnaB"
                     /locus_tag="IXT22_001648"
     CDS             30865..32232
                     /gene="dnaB"
                     /locus_tag="IXT22_001648"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAQ4863017.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33012..34304
                     /locus_tag="IXT22_001649"
     CDS             33012..34304
                     /locus_tag="IXT22_001649"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAQ4863018.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10520 a         6712 c         6828 g        10435 t
ORIGIN      
        1 cttcgcaagt ggttcttttt taacgactca gttatcttat catgtcattt ccaacatgtc
       61 aacaacttat tttttattat ttaataagtt attggtgttc ttttgaacaa ataataatat
      121 atcaacatca catgtgaaag tcaataagaa aatgcttatt tatcaacatt tctagcttac
      181 atgatcattg gttagttctg gtcctttttc gttcgtcttt ataactccga gagacgtaaa
      241 atccttttgt tttcagttta atgttcatgt tcttgtctta ttcacaccaa ctagatgtct
      301 caccttctaa aattttcctt aacaaagtgc tgcttttatc tatttctgct tttttttgct
      361 agaataatag taacaatatg actctggagg atttatttat gaaaattttg attgctgacg
      421 atgataaaga aatcgttgaa ttattaagta tctatgttca caatgagggg tatgaagcag
      481 taaaggctta tgatgggaaa gaagcattat ctaaaatcag aacaatccct gatattgaat
      541 tacttatttt agatatcatg atgcctgaga tggatgggat gcaagtagtg aaagagctac
      601 gaaaagaatc ccaaatacca atcattatgc tgacagcaaa aactactgat atggataaga
      661 tcaaaggact ggtcgctggt gcagatgatt atgtgaccaa gccatttaat ccgttagaag
      721 taatggctag agtaaagtct ttattacggc gtacaaaaat gcagattgcc ccagatcagc
      781 ctgatgtatt agaagtaaat gcattaatca tcaataaaga ctctcatgaa gttaaaacaa
      841 tcgatgggaa agaaatccag ttaacagctt tggaattcgg tatcctctac ttgcttgcta
      901 gtcatcctaa tcgagtattt agcgcggatg aaatttttga gcgtgtttgg aaacaagaaa
      961 gtattgtctc tgctaaaact gtcatggttc acgttagtca tttaagagat aagattgaag
     1021 aagcaactgg tggtgaaaaa gtcattcaaa ccgtttgggg agtgggctat aaaattgacg
     1081 caagatagta aacgagcaac tgaaaaacgc cgtcggatca atttgacttc aaaagaaatc
     1141 agcgaattgt tagcggaagg aatcatcacg attatccttt tgcttctatt aaatgtttct
     1201 attctggttg ttatcagttc ggtgatcaac agttcacctt ctttgacgaa tgcgatttgg
     1261 gattcaaaga atatttttgc agaacgattg aacactgatt tgttctggaa cggccggaat
     1321 tttattattc cctttttctt tctattagat attggtgttt tgtattggcg cttgattcga
     1381 agatatcgcc aaatgcaatt gcggcatatc atcagcgaac ttcactacat cgcaaacgga
     1441 aattatgatc atcgtatccc ttttgaactg agtggtgact taagccgagt ggtaacaagt
     1501 atcaatggat tggtggatag taccgtagca gcgattgaag acgaacgtaa aatcgaaaaa
     1561 tcaaaagatg aattgatcac gaatgtcagt catgatatcc gtaccccact cacgtccatc
     1621 attggatacc taggactgat agaagatggc cagtatcact cagaagaaga tcttttaaag
     1681 tatacgcata ctgcttatat caaagcaaag cagatgaaat ctttagtgga cgacttattt
     1741 gaatacacta aggtacgcca gcctgctgtc ccggtgaatt tttctgcctt tgacatgatc
     1801 cagttgatcg aacagttagc agctgatttt gagttggaag cttctaaaaa aaatatccaa
     1861 atacttgttc aatcaaaagt agactccctt atcatggatg gcgataccga aaaacttgta
     1921 cgtgtcttca ataatctttt gacgaatgcg ttgaaatacg gaaaaggagc aacgaagatc
     1981 gtaatcgaag tagaacgtat cggttcagaa gttgttgcaa cagtcaaaaa taacggagca
     2041 atgatcccac aacaggcaat cgataatcta ttcgaccgtt tttatcgtgt agaagaatct
     2101 cgttcacaag caactggagg aactggactt ggtttagcaa tcgctcaaag cattgtggct
     2161 ttgcacggcg gatacattta tgcaaaatca gataagcaat ggacttcttt catcatgcac
     2221 cttccaatca agaaaaatga aaaattacct attgatacac aggaagttat tgacgaaagc
     2281 tgaaatattc gctattctta ttacaattat tagaataaat gaaaaacaca gaacccagta
     2341 cactttattc tttttcagag agctgatggc aggtgtaaat cagcaaagga taatttggaa
     2401 gttccagttc gtttacgtgc cctttcgaaa taagaaaggt cggttcaaca gccgttatgt
     2461 gttcaacaag tgcagctgac gctgaacttg ggtggtaccg cgaatttcag actgattcgt
     2521 cccaagaata atgggatgga tcagtctttt tttattttca aaaaggagga aatcatatgt
     2581 tagatgtaaa aatgatgcga caaaatattg aagaagtaca agaaaaattg atgactcggg
     2641 gcgtaaaaaa agaaacatta gctgaattca tggaactaga tgaaaatcgt cgtaagctac
     2701 tagtcaaaag tgaagaatta aaaaaatatc gaaatgatgt ttctgctgag atcgcccaat
     2761 tgaagcgtgc aaaagaagat gcttctgcta aaatcgctga aatgaaagaa gtcggtggca
     2821 acatcaaagc attggatact gaaattgctg aagtggatga aaaattgaaa caaattgcaa
     2881 ctactttgcc aaaccttccc catgattctg tgccagttgg aacagatgaa gaggacaatg
     2941 tagaaatccg tcgttggagc gaaccacgta catttgcttt tgaaccaaaa ccacactggg
     3001 aaattgcaga aaatcttgat attttagatt ttgaacgtgg cgcaaaagta gccggtagcc
     3061 gttttgtcta ttacaaagga ttaggtgctc gattagaacg tgctgtctac aacttcatgc
     3121 ttgatcagca tatttacgaa cacggctata ctgaaatgat cactccttat atcgtcaaca
     3181 gtaaagcgat gtttggtacg ggacaatttc caaaattcaa agaagatgtt ttccaattgg
     3241 agaatactga tctaacatta atcccaacag ctgaagtacc attaactaac tattataatg
     3301 atgaaatttt agatggtgca gatttaccta tttatttcac tgcactaagc cctgcttttc
     3361 gttctgaagc cggaagtgct ggtcgggata cacgaggact gattcgtctt caccaattca
     3421 ataaagtaga aatggtcaaa ttttcggatg tagagcattc ttacgaagaa ttggaaaaaa
     3481 tgacagctga tgcagaagat atcttgaaaa aattgcattt gccttatcgt gtgatggcct
     3541 tatcaactgg agacatgggc ttttctgcag ctaaaactta tgacttagaa gtatggatac
     3601 ctgcacaaga tacttatcgt gaaatcagtt cttgttctaa ctgtgaagat ttccaagcac
     3661 gccgcgcaat gatccgttat cgcgataatg atggaaaaat ccactatact catactctga
     3721 atggttcagg acttgcagtt ggccgtacag tagctgccat tttggaaaac taccaaaatg
     3781 aagatggttc tgtcacagtt ccagaagcgc tcgttcctta tatggggaat ctgaaagtta
     3841 ttaaataaag aggctgtgaa aaagccgctt agtttcgagt attaagaaaa attttgtgaa
     3901 aatggctttc cacatttttg cataaattgg acttaatacc gagaaactgg cttttgaaca
     3961 ccatttatcg agaggttgtg aaatcagcga attaacctga gtattagaga aaaaaatgga
     4021 aaaatagtcc ctcatatttt accgtttgtt gaactaatac cgagggtcag ctgattgaac
     4081 accgtttagt ggagaggtcg taagcctacc ccccagctcc tagttacaag gacaaattca
     4141 aaaaacagct cttcatattt tatgaatgtt gtacttgtga ttcggaggtg gcaagggaac
     4201 actgtttatt caaaaagagg ctgggacaga agcgtttaac tccaagaaat aagaagaaat
     4261 tcacgaaaat tgcttttcaa atttttgtga atttcttctt atttccgaag gagttgcttc
     4321 tacttccgcc gtttatacgt gtttagagcg tgagacaaaa gtgttcttta cttttgtccc
     4381 acgctcttta atgtttttaa gattcaactg aatagtttgg tgcttctttt gtgatttgta
     4441 catcatgagg gtgtgattct tttaatccac tgccgctcat ttggataaat tgcgcttcat
     4501 cacgtaattg ctgtagattg gctgccccaa cataacccat tcctgaacgc aaaccgccga
     4561 tcatttggaa aataatatct gcaacacttc ctttataagc aacccgacct tcgattcctt
     4621 ctggtactaa tttatttgct tcattgacac taccttggaa gtaacggtct tttgaacctt
     4681 tttccatcgc gcctaatgag cccatacctc ggtatgtttt gaatcgacgt ccttggaaga
     4741 tttcgaattc acctggtgat tcatctgtcc ctgccaacat acttcctagc atcactgcat
     4801 gtccgccggc agctaatgct ttgacgatgt caccagaata tttgatccct ccgtctgcaa
     4861 taatcgcttt gccatattga cgagcaactg atgctgcatc ataaatagct gtgagctgag
     4921 gtacacctac accggctacc acacgtgtcg tacaaatcga tcctggtccg ataccaactt
     4981 ttacgacatc tacacctgca tcatataaag cttttgtcgc ttcagccgtc gcaacgtttc
     5041 ctgcaatcaa tgttgcatct gcaaaagttg aacggatttc ttgaattttt cggatcacac
     5101 ctgcactatg tccatgagct gtatcgatga tgattgcatc tgcccctgct tctaataaag
     5161 cattcgcacg ctcaaatgta tcgcttgtta caccaacggc tgctgctaca agcaatcgac
     5221 catgttcatc ttttgctgca tttggaaatt cgatcacttt ctcgatgtct ttgatcgtga
     5281 tcaatccgct taaacgacct tcgttatcta cgattggtaa tttttcgatt ttatgttttt
     5341 gcaaaatctt ttctgcatct tttagagagg tacctactgg ggcagtcact aagttgtctt
     5401 ttgtcatcac atcagcaatc ggcatgtgat aatctgttac aaaacgcatg tcgcggtttg
     5461 taattatccc taccaatttt ctgttttcaa gtgtttcaac gattggcaca ccactgatac
     5521 gatatttgct catcaattct tctgcgtctg ctacaagatg ctgtggcgtt aagaagaacg
     5581 gatcaatgat tacgccactt tcagaacgtt tgacttttct tacttcatcc gcttgctggc
     5641 tgatcgtcat gtttttatgg atcacaccta gtccgccttg tcttgccata gcaatggcca
     5701 tcttgctgtc ggtaacagta tccatacttg cactgatgat tggaatattc aacttaatat
     5761 ttttagctaa ttgtacgctc atatccactt cgtttggtaa cacgtgactt tctgctggta
     5821 tcaataagac atcatcaaaa gtaaatcctt ttttcgtgaa ctttgtttcc cagttggaca
     5881 tttttagtac cactcctcta atttagttta tctattaaaa taattgattt tttcatttaa
     5941 gtcaatgatc tacttggaat caagttagct ttctcataga ataccaatat aaagcgttta
     6001 catctgtgtg tattaaaaga gattgtaaaa aagctgtcct gcatcaagta ataagaacag
     6061 ccaatcaaaa acagcttctc atgtttttga attggttggg tttattaccg cagatgcaaa
     6121 cttttgaaca ccgtttagtg gagaggctgt gaaaaagctg cttagtttcg agtagtaaga
     6181 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     6241 tggcttttga acaccgttta tcgtaaaaag ggactgtgac aagacttttg tcacagtccc
     6301 ttactattat ttaactatgg ataaacaaaa tgaggttctt tactacccct agatatctag
     6361 caaaatagct gatctttttg ctagtttatc ttcttgggac ggataaactt ccaataatcc
     6421 cgtatttttt cttcaagtag taacggattg ctaaagcagt tgccccgata atgataacta
     6481 ctactggatc taatactgga ttgataactg gtggcaatag tgttgtcgca gaaaacagta
     6541 cgacccaaag aagtgtcgtt ccacctagga taagcaatgt cttacccatt cctggtttct
     6601 tgcttcgatc tgctccggga tattcatatt gatagatgta tttgtacatc atataaaaga
     6661 cccagccacc gattgcagaa cctagaacga gtgtagaaaa gccataagct ggcgttgttc
     6721 cacgtgaaaa caatccggta atcgcaatca tgatacttaa tagaccaagc aacagcaacg
     6781 tattatctaa ccacatcaat aaaggggtgg atgaattttt tacttctgct ggcttattga
     6841 tgattgcttc cgttctttca gagactgtcc caaacaattg acgggctgtt cttccgcctt
     6901 tttgttctgc aactaaagta ggcagaatgt catgaagggc ttttactttt tcttcttcag
     6961 acaaattcgc tgcttctaaa gattttttca aatcaaaaat gtactgttga tttcttttgg
     7021 ttaattttgt ttctaaacta ttgttttctt ttacgattgc tcgtaattgt tctggttcca
     7081 ttatctaata gtcctcctta gccgttcctt ttctcaacgg tcgtcacaaa agacattcta
     7141 ccatattcta cagctagttt gatagccctt ttacacatta aagcggaata acattacgtc
     7201 gccgtcttgt acgacataat cttttccttc taatcgaaca cgtccagctt cttttgctgc
     7261 atgcatgttt ccgtaatgat ccaagtcttc aaaagagaca gtttctgcac ggataaatcc
     7321 gcgttcgaaa tctgaatgga tgattcctgc tgcttgtggt gctttgattc cttttttgaa
     7381 tgtccaagca cgtacttctt gttccccagc agtaaagtaa gtagctaagc ctaacaaatc
     7441 ataagcagca cggatcaact gatccaaacc tgattcttcg attcctaaag cttctaaaaa
     7501 ttccgctttg tcttcttcat ctaattctgc gatttcttct tctgcacgag cactgaccac
     7561 gatcacttct gcattttctt ctgcagcaaa gttgcgcact tcttgtacat aatgattcgc
     7621 gtctgcatct gctacgtcat cttctgagac attggctaca taaagaattg gttttgtcgt
     7681 caataaaaat agtgatttaa cgattttttg ttcttcttca gtaaattcga tcgttcgggc
     7741 agattttcct tcttccagta caggtttgat tttatccagt acagctagtt ctgccactgc
     7801 atctttatct ttggttttag caacttttgc tacacgagta tagcgtttgt tgatagattc
     7861 taagtctgct aacactagtt ccaagttgat cgtatcaata tcttctagtg gatcaacacg
     7921 tccttctacg tgagtaatat tatcatcatc aaaacagcga acaacgtgac aaatagcgtc
     7981 tacttggcgg atatggctta agaattgatt tcccaaacct tctcctttac ttgcgccttt
     8041 tacgattcca gcaatatctg taaattcaaa agtcgtcgga acagtttttt tcggatgtac
     8101 aagttctgtt aagcgttgca aacgccagtc aggtacttct accatcccta cgttggggtc
     8161 gatcgtcgca aagggatagt ttgctgcttc tgctcctgct tttgtgatcg cattaaacaa
     8221 agttgatttt cctacgttgg gcaacccaac aattccagca gtcaatgcca taaatttatt
     8281 cactctttct ctgcattttt ttcaattact ttttttaatt tcttttcaaa atctcgacgg
     8341 gtcatcatga cgatatgtcc gcaattcata catctgattt tgatatctgc gcccattcga
     8401 atgacttccc agcgattcgt ctggcaagcg tgaggttttt tcatttcaac gatatcgtgc
     8461 aagtcgtaca taaaaatagc ctcctttttg tttattcttc atcaaattga atattcaaga
     8521 tatcaagaat tcgagtcaaa tctttttgag aaagatattc aatctcgatc ttacctttcc
     8581 catttttttc ttggatagct acacttgtac caaatttatc catcaaacga tcttcgcttt
     8641 ctcggatata atatggtttt tcctttgcta gccttgggat ttttttcttt tcttttccat
     8701 cattttgatt taactcagaa acaagctgtt ccagttggcg gacagttaaa ttttcagtta
     8761 ctgcacgatt ggctaatttc aagatcaatg ttttattttt taaacctaac agcgtacggg
     8821 cttgtcccat agataaacgc tgatcttgta ccatttcctt gacaagatcc ggtaaagaaa
     8881 gcaagcgcaa ataattggcg atataaggtc tgctctttcc taaacgacta gctacttctg
     8941 cttgtgttag tttcaggttt ttcatcagca tctcatatgc ttctgcttct tctaacggat
     9001 tcagatcttc tcgctgcaag ttttccagca ctgctacttg catcatcgct tcttcgtcaa
     9061 agtctctaac gatagcaggg atcgtttctt tttcagctag tttggacgct cgaaaacgtc
     9121 gctcccctgc aataatctca tatcctttta ctgcggaacg gcgtacgatg atgggttgaa
     9181 agacacctga ttgttcaata gaattagcta gttcctgcaa agatacttct tcaaatgttt
     9241 tacggggctg atacggattt ggtcgcagct cattcaatgg tagctggaca acggtatcat
     9301 cttttacatc caccgtctct aagttttcta aatcttgaaa cagtgcatcg attcctcggc
     9361 ctaatccttt acttttcttc acgacttacc acttcctttg ccaatgcttg gtagacttca
     9421 gctcctcgag aacgtggatc gtagtcgatg atcggttttc catgactagg tgcttctgat
     9481 aaacgaatat ttcttggaat gatcgtttcg taaacttttt cgcggaagta tttacgtact
     9541 tcttctacga cttcatttcc cagatttgtt cgtgcatcat acattgtcag taagactccc
     9601 tcgatctcta attctggatt aaagtgtttt tggactaaac gaaccgtatt cagtaattgg
     9661 cttaatcctt ccaatgcgta atactcacac tgaacaggta tcaaaatcga atcacttgct
     9721 gtaaatgaat tgattgtcag atggccaaga gaaggcgggc aatcgatcaa aatataatca
     9781 tactgactgc ttacttctgc taaagatcct tttaatcttg attctcttgc catcattgac
     9841 gtcaattcga tctctgctcc tgctaattgg agagtcgcag gcacaatact caaattttcg
     9901 tgttcagtga tcaaagttgc ctcatcaatt ggcaattcat tgactagaac atcatagatg
     9961 tctcttgtca catcaggttt tctgatcccg acaccactgg tagcatttcc ttgtgcatcc
    10021 atatccacta gcaatacttt tttgccaagg ctagcaagac aagcacctag attcaccgtc
    10081 gtcgttgttt tgccgacgcc acctttttgg ttcgcaacag atattatttg tgccatctct
    10141 tctcctccta tttgattggc tgcttattag gcagtccggg ctttcttggg tatttctttg
    10201 gggttggttt ctttttttga ataacgatga tatgccgttg atcagagaca ttcggcaagg
    10261 taaccgcctc ttctttgagg aatttaccac ctaataaagc aatcgcttgt tttgcttctg
    10321 tcaattcctc ttcacttttt gctgctttca atgcataaaa atagccttct tgtttagcca
    10381 agggcaaaca caattccgct aacacattca aacgagcaac cgcacgagca gtgacaaggt
    10441 caaatgatgc acgaaagtga ggattttgcc caaatgtttc tgcccggtca tgatataagg
    10501 aagcatcgat tcctaataat cgggttaact cagataagaa ggttattcgt ttattcagag
    10561 aatcaacgat cgttatctgc agttctggaa aggcaatttt taaaggtatg ctaggaaacc
    10621 ctgcccccga accaacatcg cataaagata aaggttgcgt aaagtctact tcaaatgcta
    10681 atgtaagtga atcgtaaaaa tgcttcagat atacgtcttt ttcatccgta atagctgtaa
    10741 ggttcatctt ttcgttccat tcgactaatg tccgataata aatagcgaat tgattcattt
    10801 gatgatcggt aagctctatc cctttttctg ccaaggattg gcgaaattct tctggtatca
    10861 taaatattcc tttcattgtg aaacagcaat tgtttcacag attctctccc tactttaacg
    10921 caaaatctct agacatgcaa tccttccata tggattctta aaaatttgaa aagtaagaaa
    10981 agccgataga ctttttcttt ctagtatgac tcataaaata tacacagaag agagaactag
    11041 ctttgagcaa tttctgcaaa aactagttct ctcttctatt tattattacg tattacgctg
    11101 gttcactgac tttcgcaatc ttcccttgtt cgatatagac cattaggata cttaggtctg
    11161 cagggtttac gccactgatt cggctagctt gggcaattgt ttctggttgg attttctgca
    11221 atttttgttt tgcttctgtt gctaatccgt tgattgctgc gtagtcgatg ttttctggaa
    11281 tctttttcgc ttccatgcgt tttaattttt ctactttttc catggctttt ttgatgtagc
    11341 cttcatattt gatttggatt tctacttgtt cgatttcttt tcgtgtcaat tcttcatttt
    11401 ctggaataaa ccgtagaagt tctgcataag taatctcagg acgtcttaaa aagtcgcttg
    11461 ctagtacacc atcttttaat ggtgccgcat taatcgttgc taaaaagtct tggacttctt
    11521 ctgttggttt gattcgtaca ttcatcaaac gtttgatttc ttgttcaact gcttcttttt
    11581 tcttcaaata attcttgtat tgatcttctt ttactaagcc tacacggtga cccatttctg
    11641 ttaatcgcaa atctgcatta tcatgacgta aaagcagacg gtattcagca cgtgaagtca
    11701 gcaaacgata aggttcgttc gttccttttg ttaccaaatc atcgatcatg acaccgatgt
    11761 aaccgtcact tcgtttgatc actaaaggtt cttttccctg aactttcaaa gctgcattga
    11821 taccggcaat cagcccttgt ccagccgctt cttcataacc gcttgtacca tttgtttgtc
    11881 cagctgtata aagattttca acgactttag tttctaatgt cggacggagc tggtgtggct
    11941 ctactacgtc atattcgata gcatatcctg tacgcatcat ttctactttt tctaatccag
    12001 caatagaatg aagcatgttg acttgaacat cctctggtaa agaagtagat aaaccttgaa
    12061 catagacttc ttccgtattt aagccttctg gttccaaaaa taattgatga cgtggtttgt
    12121 ctgcaaaacg cacgatctta tcttcgatgg atggacaata gcgagcgcct accccttcaa
    12181 cgatccctgt aaacattggg gcacgatgta agttgtctcg aataatttgg tgagtcgtct
    12241 cacctgtata ggtcagccag caagattcct gatctagttt ataggcacta tctggtgtgc
    12301 tgaagctaaa atgattcggc tctttgtcac caggctgctc ttctgtaaca gaatagtcga
    12361 tcgtacttga ttttactcga ggcggtgttc ctgttttgaa ccgttcgata gcaaagccaa
    12421 gttcttttag atgattcgct agtccaatag aaggttgaga gttattcgga cctgatgaat
    12481 atttcaattc accgataatg atttctccgc gaagtgctgt tccggctgta ataacaactg
    12541 ctttggcccg gtagctcgct cctgtggacg tcactactcc atgacaaaca ccatcttcga
    12601 cgatcagttc ttcgacgatt ccttgtctta gcgtcaaatt tggttctttt tcgatcgtat
    12661 gtttcatttc tgttgaataa gcatgtttgt ctgcttgtgc tcgcaatgct cggacagctg
    12721 ggccttttcc tgtgttcaac atacgcattt ggatataggt tttatcgata ttcttaccca
    12781 tttctccgcc taacgcatcg atttctcgaa cgacaacgcc tttagctggt ccgcctacag
    12841 aaggattaca tggcatgaat gctaccatgt ccaaatttat tgtcagtaat aatgtttttg
    12901 atcccatacg tgcagcagca agtgcagctt ctgaaccggc gtgtcctgcg ccaacaacga
    12961 tcacgtcata cgcatctgct tcataatgtt ccaatcgttt gttcctcctt ttattttcct
    13021 aaacaaaatt gactgaataa ttgagtgatt agctcatctt gtacactgtc gccgacaact
    13081 tctcctagat agtcccagca acgcgtcata tctatttgaa cgagatccac aggcattcct
    13141 gaatcaatac ctgcaatgac ttcttcaagt gagagggaag ctttttctaa caacgcgata
    13201 tggcgggtat tagaaacata agtagcgtct ctttctcctg tttctccgct gaagaataaa
    13261 tcagaaatag ctgattccaa acgatctagt ccgtcgtttt tagctacgga aattgaaaaa
    13321 actggttcat tttcgatcaa tttcttcaat ttttcttgtt ccagctgtgc tggcaaatct
    13381 gttttattta gaagaatgat ccgtttcaat ccacttgtcg cttccaataa ttgttcatct
    13441 tctgctgtca gtggttcgct ttggtttaga acaagtaaga tcaagtctgc ttctgctaat
    13501 gcttttcggc ttctttcgac cccgatccgt tccaccacat cttctgtttc ccgaattcca
    13561 gctgtatcga ttagcttgag cggtaccccc cgaacattga catactcttc gattacatct
    13621 cgagtcgttc ctgcaatatc cgtaacgatt gctttttctt ctcttaacaa atggtttaac
    13681 aaacttgatt tgccgacatt tggccggccg atgattgccg tacttaaccc ttcccgcaga
    13741 accttccctt gcttggatgt agcaagtagc gcttggattc tttgttggat catctgcgct
    13801 ttttcaagca ataacttcgt agtcaattct tcgacatcat catattctgg ataatcaata
    13861 tttacttcta cttgtgctaa tgtctctaaa atctcttgtc tcaatgagcg gatcaaagca
    13921 gacagattgc cgtctaactg attaagagct agtcccattg ctttgtctgt ttttgcccga
    13981 atcaaatcca tcacagcttc tgcctgtgaa aggtcaacac gaccattcaa gaatgctcgt
    14041 tttgtgaatt cgcctggctc agctaatctt gcaccttctc ttaacaatag ctgcaaaatt
    14101 tgattgacta caacgatccc accgtgacaa ttgatttcta ctacatcttc ccgcgtaaat
    14161 gtctttggtg ctctcatcac ggagaccatg acttcatcga caagctgatt gctcttggga
    14221 tcaacgatat gtccataatg gatcgtatga cttggtactt ctgataatcg tttgtttcca
    14281 gattgataaa ctttatctgc tagttgcaca gcttgatcgc cacttaaacg aacgatactg
    14341 attgcacctt ctccaggtgg ggtagaaatt gccgcaatcg tatcaaattc taaagtaatt
    14401 tcagccattt tttcacttcc tttttcattt tgcgcacaaa aaaagtgccc actccaccct
    14461 ttatgcacaa taaacggtga acttcgcact ttgactgctt gttcttgatt aaattctggt
    14521 catagattat cacacttgct ataaggaatc aagtgtttaa aacaattaga tgaagttgag
    14581 cctgttctgc ttccattacc ttatatttaa ttgtccttgg atgtctcttt gcgttctttg
    14641 gtttattcga agagaagata ctgtataaac aaggctttat ctttcttaaa aaaaacggta
    14701 cactaaatgg tagcgctatc taaactatac acttttgaaa ggagaaaata tgtgagcccg
    14761 ttcagatctg ctgcattgga agaagaaagt gaccctcgga tcaacgatgt cgttttatct
    14821 acagggaata tcaaccagaa atatatcgtc cgcgatatcg tttttgttgt ggaatgctta
    14881 gaagctgatt tgtttgaccc atcttttccc aaagatgacc ttttcttaac aacgaagagg
    14941 aaattaaaga cgaaggtact tgaatatggt gcgaatgcag taatcaactg tcattttgag
    15001 tatcagcaaa aaaaacgcga cggaaagtat tttctggaac tttttgctta tggaacagtg
    15061 atccaattta tccaaacaac gattggttaa atgaaacaga caaaaaaagc ggatcaaaac
    15121 tgaagacagt ttcgatccgc ttttttctat caaagttagt gactacttca tcgtatactc
    15181 tgataagaat gatttctagt aaaatatact tggtttgaaa aactttgtca acgtgattta
    15241 ttcaaaaagt aatggaatca ataatatttt ttagcaggtt ctactactaa ataacgataa
    15301 ggttcctcac cttccgaatg tgtttttaca tgttcatctt tgcttaatgc agcatggatt
    15361 tgtttacgtt caaatgcagg cattggttct aagaaaacag gctgccctgt ccgttttact
    15421 ttttcagccg tgcgatcagc taaacgctga atgatctctt ggcgcttttc acggtaattg
    15481 cctacattga ctactacaga cagcttattt cttgctaaac gatggatgaa gacttgtgcc
    15541 agatattgca atgcattcag tgtttttcca tgtttcccaa tcagtatgcc ttgcttttgt
    15601 gtttctaaat ggaaaacaac catattattt gattctcttt ccattttgac aagagctgga
    15661 gcatcaagct gttttgaaat ttcagtaaga taaactgcca attccgttaa agctgcttca
    15721 tcacctagct cacttacttc ttctgttttt tcttcaagaa tcgtttcgtt gactacctcg
    15781 atctcagctg ttggttcttc ttccaaaatt tcttctacag tctgttctac tgtttcagaa
    15841 actttttcgc tgatacttgg ctggatcgaa agccgtgcat tctttcgacc cattcctagg
    15901 aaaccttttt ttccttcttc cagtatttcg atttcgactt ggtctttggc caaacccaaa
    15961 tcagccagac ctagttggac agcttcgtct attgttgcag cttcataaat cggcattagc
    16021 attacctccc ctattatttc cgttttttct taggattcat tgctttctta agagcacgtt
    16081 ctctttcgcg gattctccgt gcttcttctt cacgctcttt tcgaattttg aaagggttgt
    16141 tgatcagcag cgtttgtaca acttggaagg cattggaaac tacccagtat aatgaaagac
    16201 cgctggctaa attgacaccc atcactaaaa tcattacagg catcacgaaa ttcatgatct
    16261 tcattgatgc attcgattca atttgactca tgctagataa atacgtactt gcaaaagtaa
    16321 agattgctgc taaaatcggc aaaataaatg ttggatccgc gttccctaag ttcaaccata
    16381 agaaatgccc ttgtttcaac tctggtacac gtgaaataga ttgccataac gccatcaaga
    16441 ttggcatttg tactaataaa ggaagacaac cagcatatgg attgacgcca ttttctgcat
    16501 ataaacgctg ctgctcttct cttaacttac tttgtgtttc cggatctctt gaactatatt
    16561 gttgctgcag tgcttttaat ttcggttgta attcttgcgt tttacgcatg ctctttgttt
    16621 ggaaatgcat caacggcaat aggatcacgc ggatgatcag tgtaaataaa atgatcccta
    16681 tccctgcatt accaaatgac aacgccttga tcgcctcagc aaagtaataa acaatataac
    16741 gatcccaaat tcctgtactc tgtgcgctga cttccccagt tccgcaaccg gataagacga
    16801 tgaccaaact aacgataccg gccatcaaaa gtaaacgttt gtatttcttc acttactctt
    16861 ttcctctctg tcgattattt ttgcaagttt taagacgtgg actaaattgg agcgaacctc
    16921 atcataagtc aaccccttca cacttggtct agcaatcaca ataaaatcca actccggatc
    16981 aatttcttct tttatagaat aaactgctgc tcggattttt cgtttgactt cattgcggtt
    17041 taccgcgttg ccgacctttt ttcctacaga taaaccaact cgaaaatgag gctgtcccgg
    17101 tttttccaaa cggtaaacga cgaatttgcg gttagcaaaa gaatctcccg tatggaacac
    17161 ggcttgaaac tctcgttctt tttttactcg atacgctttt ctcattagtt ttctttcctt
    17221 ttctatctct cacttacgct cataatcata ccataattac gattgtcctt tcatcatttc
    17281 cctaaaaaag agtataaaaa aaaccactga aaccccagtg gcctaagctg aaagaacttt
    17341 tcttcctttg cgacgacggc tagctaacac acgacgtcca tttttagtac tcatacgttt
    17401 acggaatccg tgaacttttt gacgtttacg tttatttggt tggtatgttc ttttcatata
    17461 ttccacctcc aaaatgttct tatctatttt ataaacacag acatactttg atagtataac
    17521 gacaaagtag tgattttgtc aatataaaat agaagatcga ttgttaaaac ttatccacaa
    17581 gattattttt ttctatggga atcctatgtg gaaaaagtta tgcacaggga ttatccacag
    17641 ataataaaag gctggtttta cacagaaaac acacgtgtaa aaaaagtaat ccacaatcag
    17701 gcgatttcct gtgtattccg tctcctaact attggtatat ctgtattttt tatccacaga
    17761 cgcaagagga aatctattgg tttttacgag ttttccacct gtgcattagt ggtgtggaaa
    17821 actttttttg acaactgtgt ttttctcttt tttctttttg tcgattgtgt ggataattgt
    17881 aattaaaaaa tttttttctt cggtttctgt ggaaaactat tgaaaaaaat gctaaattag
    17941 tactagttat tcacttttta atgaaggagg aggccttata tggtatccct cgatgcttta
    18001 tggaatgaat taaaagcaac ataccaaaag gatttatcgc ctgctagcta taatacatgg
    18061 atcgaaacag cgaaccctcg aacccttgat caaaaccagc tcgttgttga ggttcctagc
    18121 aagattcata aagaatattg ggaaaaaaac ctggcgacaa aaatcgttga agtcggttat
    18181 atgttatcag gaaatgagat tatccctcgc tttattactg gcgaagaagc agagcaagaa
    18241 gaagttatag aagaaaaaaa tccaaaagtt gtggcaccta gtccgctaaa aaaagccatg
    18301 ctgaacccta aatatacctt tgatacgttt gtcattggta aaggaaacca gatggctcat
    18361 gcagcagcgc tcgttgtagc agaagatcca ggttctattt ataacccgct cttcttttat
    18421 ggaggcgtgg gacttggtaa gactcacttg atgcatgcaa ttggtcatca aatgctgcaa
    18481 agtcagccta atgccaaagt aaaatatgta agcagtgaaa cttttgctaa tgatttcatc
    18541 aattcgatcc aaaacaaaac agcagaagag ttccgtcaag aatatcgaaa tgttgattta
    18601 ctgctagtgg atgacattca attttttgca gaaaaagaag ctacgcaaga agagtttttc
    18661 catactttca atgccttgta caatgaaggg aaacaaatcg tactaaccag tgatcggttg
    18721 ccaaacgaga ttccgaaact gcaagaacgc cttgtttctc gctttgcatg ggggctgtct
    18781 gttgatatta caccgccgga tcttgaaaca agaacagcga ttttacgtaa aaaagcggcg
    18841 gctgaacgtc tagagatccc agatgacaca ctaagctaca tcgcaggaca aattgattct
    18901 aacattcgtg aattagaagg tgcgcttgtt cgagtgcaag cttttgctgc gatgaatagt
    18961 gaagatattt cgactagtct agctgcagac gcactgaaaa cgttaaaatc aggaaaagga
    19021 catcctcaat tgtcaatcct gcagatccaa gaagaagtgg caaagtatta tcacatccaa
    19081 ttgaaagatc tcaaaggaaa gaaacgcgtc aaatctattg ttgttcctag acaaatcgct
    19141 atgtatttgg cacgtgagct cacagataat tctttaccga aaatcggagc tgaattcggt
    19201 ggcaaggatc atacaacggt tatccatgct catgaaaaaa tccagcagct gatggattct
    19261 agtgtcagta tgcaaaatga agtatcagaa atcaaaaact ttttactaaa ttaatttgtc
    19321 gattctatca actgaaaata gcatgtggat aaaagaaaaa aacgttcaaa agttatacac
    19381 actttttcca cagctgtttt ttcgtttctc tcttacgttt tttgagtttt ccacagaatc
    19441 aacatgccct attactttta ttattctttt taactaataa taaataaaca aacattcaaa
    19501 ggagatacat catgaaagtt actttaaacc gagctagctt tatgcaggaa ttgcaaactg
    19561 ttcaacgagc tatttcaagc aaaaccacga tccctatttt gacaggtgta aaaatcacac
    19621 tgacacaaga aggtttgact ttgacgggga gcaacgctga tatatcaatt gaaacttttt
    19681 tgtctgttga aaacgaaaaa gcaaatatgc aaatcgaatc tactggttcc attgttttac
    19741 aagcacgttt ctttagcgaa atcattcgga gacttcctga agaaacattt actttagaag
    19801 ttttagaaaa taaacaagta gcgatcactt ctggaaaagc gaattttatc gtaaatggat
    19861 tagatgcaga taactatcct catcttcctg ttgtcgaaag ccataaccag atgaaattac
    19921 ctgtacacgt attgactaaa ctaatcaacg aaacagtttt tgctgtctca caacatgaga
    19981 gtcgtccaat cttgacaggt gtgcatttca ttttatctga taattcttta ttagctgtag
    20041 ctactgattc tcaccgtcta agtcaacgcg tgattccagt agaacaagcg gctgatcatt
    20101 ttgatattgt tattcctgga aaaagtttga tcgaattatc tcgctcatta acaaatgaag
    20161 aagaaatcgt cgaaatcagc attatggaaa accaagtgtt gttcaaaaca gaaacgatgt
    20221 atttctattc ccgtttgcta gaaggaaact atccagatac caatcgtttg attccttcaa
    20281 gttttaatac agaggttgaa ttttctgttc ctagcttttt agcggcgatc gaacgggctt
    20341 ctttactttc tcatgaaggc cgtaacaaca tcgttcgttt atctattcgt ccagatgcgg
    20401 ttgttttata cggaaattcg ccagaaatcg ggaaagtaga agaaagcttg agttatacag
    20461 caagcagtgg cgatccatta gatatttctt tcaatccgga ttatatgaaa gcagcgttgc
    20521 gtgcatttgg agatatgagc atcaaagtga aatttatctc tgctattcgt ccatttacat
    20581 tggaaccaac ggaagatggc gttcaattta ttcagctgat tactcctgta cgtacaaatt
    20641 aacaatgatt ttcaatgttc ttgaaaattt aattgaaaag aaatagaaaa aataaaattt
    20701 taaacagaag gccctaaaat ctcttttaag gctttctgtt tatttttgtt taaatcacct
    20761 tttttagatt aaatcgtctt atatggaaaa atatatggat aaatttgttt tattgcgaaa
    20821 aaaaaggtat aatagagtat acttttaata atgaaaatga gggatgggca ttgaaacaac
    20881 aagtcattct aaatacggaa ttcatgacgt tgggccaaat gttgaaagaa gtcacagtta
    20941 tcggtagtgg cggacaagca aaatggtatt tggcagaaaa cactgtgtta gtcgatggcg
    21001 aaccagaaaa tcgtcgtgga cgcaaacttt atcccggcat gatggttgaa gttccagaag
    21061 taggaacttt ttttatggta aaaaaaggaa acgacgataa tgaggctgaa taagctgtat
    21121 ttaaaaaatt atcgaaatta cgaagagctg aacatcgaat tttccaagaa cctcgtcatc
    21181 tttttaggag aaaatgcgca aggaaaaacg aatcttttgg aaagtatcta cgtattagct
    21241 atgacgcgaa gtcatcggac aagtagtgag caggaattga ttggctggac tgacgatcag
    21301 gcgatgattc aaggagagat cacaaaaggt tcatccactc ttccattaga aatcttatta
    21361 tctaaaaaag gccgaaaaac caagatcaac catatcgaac agaaaaagtt aagtacttac
    21421 gtgggacaaa tgaatgtcat tttatttgca ccagaagatc tttctttagt aaaaggcagc
    21481 ccgcagatca ggcggaagtt tttagatatg gaattaggcc agatcaatcc aatctatctt
    21541 tatgatcttg tccaatacca agcaattttg aaacaaagaa accagtactt gaagcaattg
    21601 aatgaaaaaa aacaaactga tttgctttat ttggatattt tgtccgaaca actagcagcg
    21661 tttggcagca aagtattgaa agcaagagca cagttcgtca agcgattgga gttttgggct
    21721 aattctttgc atcagcaaat cacccatcaa aaagagcagc tggaaatcga gtatctcacc
    21781 gcagtcgatt ctttagaaac acatacgcaa gagcaaatcc aagaacaatt tctcgcactt
    21841 ttgaaccaaa ataaaaagaa agaccttttt cggggaacaa cgacagttgg tcctcatcgt
    21901 gacgatcttt ccttttttat taatcagaaa aatgtgcaga cttatggatc gcaaggacag
    21961 caaagaacaa ctgcactaag tgtcaaatta gcagaaatcg atttgattaa agaagagaca
    22021 ggggaatatc caatcctttt gttagatgat gtgatgagcg agctggatga taatcgtcaa
    22081 ctccatctgc tagaaacaat cgaaggaaaa gttcaaacgt tcttaacaac aacgacactt
    22141 gaccatgtaa aaaataaaat gactgttgaa cctgagattt tttatgttca acaagggaaa
    22201 ctaaaaggag aagaaactga atgacagaag aaagaagttt agtagaacgc gctaaagagt
    22261 atgatgccag tcagattcaa gtacttgaag gacttgaagc cgttcgtaaa cgacctggca
    22321 tgtatatcgg ttcgactagt tctgagggtc tgcatcacct tgtttgggaa attgtcgata
    22381 attcgatcga tgaagtatta gcaggttttg caacgaaaat ccatgtgatt attgaaaaag
    22441 acaacagtat caccgttatt gacgacggtc gggggatacc tgtagatatc caggcaaaaa
    22501 ctggacgtcc tgcagttgaa acggtcttta ctgttttaca tgctggagga aaattcggcg
    22561 gtggtgggta caaagtttct ggtggacttc acggagtagg atcttctgtt gtaaacgcgc
    22621 tttctacaca gcttgatgtc aaagtataca aagaaggaaa tgtgtactat caagaatatc
    22681 gtcgtggagc tgtagtggac gacttaaaga ttatcgaaca aacggatcgc catggaacaa
    22741 cggttcactt tacgccagac cctgaaattt ttacagagac aactgagttt gatttttcaa
    22801 aattggctac ccggatccgt gaacttgctt tcttgaaccg cgggatgcgt atatcgattg
    22861 aagacaaacg agaagaagaa ccagtcatca atgaatacca ttatgacggc gggatcaaaa
    22921 gttatgtcga atacttgaat gcaaacaaaa ccgtgatttt tccagaacct gtatatttgg
    22981 aaggtgaaca gcaagatatc gcagttgaag tctctatgca atatacagac ggctaccatt
    23041 ccaatatcat gagttttgcc aacaatatcc atacgtatga aggtggaaca catgaatcag
    23101 gattcaagac tgctttaact cgtgtgataa atgattatgc ccgaaaacaa aagctgatga
    23161 aagaaaatga cgacaacttg accggtgaag acgtgcgaga aggattgaca gctgttattt
    23221 ctatcaagca tcctgaccct caattcgaag gacaaacaaa aacaaaattg ggcaattccg
    23281 aagtacggac agtcactgat cggttattta gcgaacattt catgaaattc ttgctggaaa
    23341 acccaagtgt gggccggcaa attgttgaaa aaggattact agcttccaga gctcgtctag
    23401 cagcgaaacg tgcgcgtgaa gtaacgagac gtaaaggtgc tttagagatt agtaatctgc
    23461 caggaaaatt agcggactgc tctagcaacg atcctgaaaa atgcgaattg ttcatcgtcg
    23521 aaggagattc ggccggcgga tcagctaagc aaggtcgtaa tcgagagttt caagccatct
    23581 tgcctattcg tgggaaaatc ttgaatgttg aaaaagcaag catggacaag atcttggcaa
    23641 atgaagagat ccggtcttta tttactgcta tgggtacagg gtttggagaa gattttgatg
    23701 tatcgaaagc tcgctaccac aaattagtta tcatgactga tgccgatgtc gacggcgcgc
    23761 atatccgtac attgctgctg actctttttt atcgttacat gcgtcctatt gttgaagctg
    23821 gatacgtcta tattgctcag ccacctttat acggggtaaa acaagggaag aatattacgt
    23881 atgtacaacc aggaaaaaat gcagaagaag agttgaaaca agtcgttgct tcacttcctg
    23941 cctcaccaaa accaagcgtt cagcgttata aaggacttgg agaaatggat gatcatcaac
    24001 tatgggaaac aactatggac ccaagcaatc ggatgatggc ccgcgtcagt gtggacgatg
    24061 ctattgcagc agatcagata tttgaaatgt tgatggggga tcgagtagaa ccccgtcgtg
    24121 cattcatcga ggaaaatgca cactatgtga agaacttaga tatttaatca tgaaggagga
    24181 aaaagaatga gtgaagaaat cagagaaaac atccatgatg tcaatctaac cagcgaaatg
    24241 aaagactcct tcatcgatta tgcgatgagt gttattgtcg cacgtgcact tcctgatgtc
    24301 agagatggtc tgaaacccgt tcatcgccgt attttatacg gcatgaacga attaggtgta
    24361 acaccggata aagcccataa aaaatctgcc agaatcgtcg gagatgtcat gggtaaatac
    24421 catcctcatg gagacattgc gatctatgag tcaatggtac ggatggcaca gccattcagc
    24481 taccgttata tgctagtgga tggtcatgga aactttggtt ctgttgacgg tgacggtgcc
    24541 gccgctatgc gttataccga agcacggatg agcaaaatcg ctacagaaat gctgcgtgat
    24601 atcaataaga acactgttga tttccaaagc aactatgatg atacagaaaa agaaccagtt
    24661 gtactacctg ctcgcttccc gaatctttta gtgaacggaa caacggggat cgccgtaggt
    24721 atggccacga atatcccacc tcataacttg tctgaggtag tagcggctat cgatttgctg
    24781 atggataatc ctgatgtgac gaccaatgaa ttgatggaag tattacctgg accagatttt
    24841 ccaacaggtg gtttggttat ggggaaatca ggaatccgaa gagcgtatga aacaggtaag
    24901 ggttctatta ccgtacgtgc aaaagttgag attactgaga tgccaaatgg taaagaacgg
    24961 atcatcgtga cagaattgcc ttatatggtc aataaagcaa aattgatcga acggatttct
    25021 gaactgcaca gagacaagcg tatcgaaggg atcacagatt tgcgggacga atcttcccgt
    25081 gaaggtatgc ggatcgtcat tgacatccgt cgtgacgcca gcgcatccgt tatcttgaat
    25141 aacttatata aattgacatc cttgcaaaat tcatttggat tcaatatgtt ggcgatcgaa
    25201 aaaggtgtgc cgaaagtttt gagcttgaaa caaatccttg aaaactatat cgaacatcaa
    25261 cgcgaagtca tcacacgacg gacggtcttt gaaaaagaaa aagcagaagc aagagcacac
    25321 atcttagaag gtttgcgtat tgctttggat catatcgatg aaatcattgc gattatccgc
    25381 gggtctaaat cagatgacga ggcaaaagca acaatgatcg aacggttcga tttatccgat
    25441 cgccagtctc aagctatttt agatatgcgt ttacgccgat tgaccggttt ggaacgggaa
    25501 aaaatcgaaa atgaatacca agaactctta aaactgattg aagatttaac tgacattctg
    25561 gcaagaccag aacgtgttac agaaatcatc aagaatgaat tagcagactt gaatcaacga
    25621 tttggtgata aacgacgcac agaattacta gtcggtgagg tcttaagtct ggaagatgaa
    25681 gatttaatcg aagaagaaga aatcgttatt acattgacaa acaatggtta catcaaacgt
    25741 ttggcaaata atgaattcag agctcaacga aggggtggac gtggtgtcca aggaatgggt
    25801 atccacaatg acgacttcgt caaaaatctg gtttcttgtt ctacccatga tacattgtta
    25861 ttctttacga ataacggaaa agtgtatcgg gcaaaaggat acgaaattcc agaatacggg
    25921 cgtacagcca aaggaatccc aatcatcaat ttactaggta tcgattcgag tgaaagcatc
    25981 caggcaatca ttgcggtgac gggagaagca gaagaaggcc actatctctt ctttacgacg
    26041 cgtcaaggta cagtaaaacg tacttctgtc actgcttttg ctaacatccg aagtaatggt
    26101 ctgatcgcaa ttggtttgaa agaagacgat gagctcgtca atgtgctact gacagatggt
    26161 caatctaata tcattattgg aacacataac ggctactctg tcactttcaa agaagaagca
    26221 gtccgcgata tgggacgtac agcttccggg gtcagaggga tacgcctgcg tgaggaagat
    26281 tatgtcgttg gggcagcctt aatgaaggaa aatcaagaag tattagtgat cacagaaaaa
    26341 ggttacggaa aacggacaaa agtatcggaa tatccagtga aaggccgcgg aggtaaaggg
    26401 atcaaaacgg cgaacatcac tgaaaaaaat ggtccactag ctggattgac cactgtttct
    26461 ggagatgaag acatcatgct gattacagat aaaggtgtca ttatccgttt caacgtatcg
    26521 actgtttctc aaactggacg ttcaacatta ggcgtacgtt tgatgaagat ggaagctgat
    26581 acgaaagttg tcacgatggc agcagtcgaa ccagaagctg cagaacaaac agttgaagaa
    26641 caaggatcag aagaataacc atcaagacta agtgtgtaag ctagcaagaa taaccgatta
    26701 aaaaatctgg ttattcctgc tggctttttt gattagttga atttctctta aaatattcga
    26761 aactgttcat tctgtattgc ttttgaccaa aatagagtgt ataattagag cttgtgagta
    26821 gtctaattaa ttagataact ctccttgctc ttaggaacct aagagccgaa agtccacagg
    26881 gaggtgaata tcaatggaaa acacgaaata tgaaatcatg tacattattc gtccaaacat
    26941 tgatgaagaa gcaaaaactg ctttaatcga acgtttcgat gcaatcttga aagataacgg
    27001 agcagaagtt atcgaatcaa aagattggga aaaacgccgt ttcgcttatg aaatgaacgg
    27061 ttaccgtgaa ggtatctatc acatcgttaa agtatcttct ccatcatcag caaatgctgt
    27121 caatgaattt gaccgtcttg ctaaaatcaa cgacgatatc attcgtcaca tgattgttaa
    27181 agaagaagct taattgttgt ttcatgtgaa acaatagaaa acgatgagag gagatgacta
    27241 ttttgattaa taatgttgta ttagttggac gtctgacgaa agatccagat ttgcgttaca
    27301 cagcaagtgg tacggcagtc gcaacattta ctttggctgt gaatcgtaat tttacaaacc
    27361 aaagcggcaa tcgcgaggct gattttatca actgtgtgat ttggcgcaaa tcagcagaaa
    27421 ctttagcaaa ctatgctcgt aaaggaacac ttttaggtgt tactggacgt atccaaactc
    27481 gttcttatga taatcagcaa ggacaacgtg tatacgtgac agaagtagta gctgacaact
    27541 tccaattgct ggaaagtcgt tctgcatctg aaaatcgcca acaaagcggc ggattccaaa
    27601 gttctggtca atcagctggc ggatttggcg gaaacaataa ctctaatcaa acatctcaat
    27661 catccaacgg tatgcctgat ttcgaccgtg atacttctga cccattcggc tcaagttcaa
    27721 cgatcgacat ttcagacgat gatttaccat tctaaacgaa tttgatagga gggaaataga
    27781 atggcacaac aaagaagagg cggacgtaaa cgtcgtaaag tagactacat tgctgctaac
    27841 catattgaat atatcgatta taaagatatc gaattactaa aaagatttat ttcagaacgc
    27901 ggtaaaatct tgccacgtcg tgtaactggt acaggcgcta aaaaccaacg taaaattact
    27961 gttgcaatca aacgcgctcg tatcatgggc ttgctacctt tcgttagcga agactaataa
    28021 atcctaggaa ttgaatgact gatccttttg atcagctatt caattccttt ttttctgtaa
    28081 aaataacctc tattcgttta gtcgctcgaa tgacgaaagt tatggtaaaa tcaaattagt
    28141 catatatggg aggaaaatta tggaaaataa aaacaatcat ttatccccga aacctctctt
    28201 ccttatcctg tttatattaa tcgaagtatt ggtagtctta attttaccat ttcgttttgt
    28261 tagcgcttcg gtcattctat tgatgaattt atggggtgtt cgctattggt tgaaaatgaa
    28321 acgttggctt attttaaata aacgtgaaaa aatccagcag gcttcgactg tagctgaaac
    28381 caatctagct tatgtctcag aagtcatgcc tgtaggagtg attgcttatc agccatcaag
    28441 ccaaaaaatc gaatggctca atccattagc attgaaaatc aaagatcaaa gtggattaac
    28501 agaggaagaa ttgctagata ctttttttac tgcaaaagaa aaaaagaaaa accaagtcta
    28561 tctagcagat aaaacatttc agtttgatat ggatacagta aagggtgttg tttattttaa
    28621 tgatattacc caaaaccagt tgttaaaact ccatcagacg aacagtcagc cggtgattgg
    28681 tattttatct attgataact atgcagatgc cattgataaa ttagatgaca aagagatttc
    28741 ttatttgaac tctttcgtca ctacactagt ttctgactgg atgaatgaat accatgtctt
    28801 tttcaaaaga atcaacgcag aacggttttt cttcgtagca cagatgatcg atctgaaaaa
    28861 gatgatggat aaaaaatttg atttgctgga tcgctttcga gcagaagctg aaaaacagag
    28921 ctcgcctatc acccttagta tggggattgc ttatggctca agaaccctcg atgaaatcgg
    28981 tggagaagct cagaataatt tagatgttgc tttagtccgt ggaggcgacc aagttgtcgt
    29041 gaaagaggta aaagaaggag caaaacctgt ttattatggg gggaaatctg ctaagaatgt
    29101 caaacgcacg cgtgttcgtt ctcgagcgat gagtaccgct ttgcgtcgga tttttgatga
    29161 aacaggcgat gtgtttatca tggggcacaa gtttccggat atggatgctt taggctctgc
    29221 ttttggtgtc agttgtctgg cacgcttcaa ccagaaaaaa gcttacatcg ttatcaatga
    29281 gaacgagatc attccagatg tagaacggtg tcttgaagaa atccataagc atcctgaatt
    29341 agaaatgcaa ctaatctctc cagaacgtgc catagagctg aaaaaagaag aggacctcct
    29401 cgtgatggtg gattaccata aaccttctct atcgatctct cagggcctat atgagcaatt
    29461 tgataagatt gtgatcattg atcaccatcg tcgtggggaa gagtttccaa gtaaacctct
    29521 gctgacttat attgaatctt cagcttcttc agcttcagag ctagtttctg agctgatcca
    29581 ataccaaagc agcaaaacaa atcgcttaga tcgttttgag gccacattat tgcttgcagg
    29641 gatggttgta gatacaaata gtttcaatgt ccgtacaact gcacgaactt ttgacgttgc
    29701 cagctattta aggtcttgtg gagcagacgc atccttagta caatatttat tgagctcgga
    29761 tttagcgaca tacttggaga tcagcaattt gattgctgga agcgactatg tgacttctga
    29821 tattgttgtg gcggcaggga cagacgaaaa agagtataat agtgttatag cagcaaaaac
    29881 agcagataca ttgctttcga tgatcaatat caatgcagct ttcgtcatta caaagcggac
    29941 agacggcttg attgggatca gtgccagaag taccggcacg atcaacgtcc aaatcatcat
    30001 ggaatcctta ggtggcggag gacacttcac aaacgcagct actcaactgg aaaatacgac
    30061 agttgaggaa acaaaacaga agctatttgc tgcaatcaaa gaaaatatga atcaaatata
    30121 tgataaggag taatccaaat gaaagtaatt tttttacaag atgtaaaagg aaaaggtaaa
    30181 aaaggggaca tcaaagaagt tccagcaggt tatgcacaaa attatctaat caaaaataac
    30241 ttggcaaaag aagcaacgaa aagcagtatc agtcagttag caggacaaaa gaaagcacaa
    30301 gaaaaacacg aagctgaaat cttggaagaa gctaaaaagt taaaagaatt cttggaaaaa
    30361 gaagatactg tagtcgaatt gaaggcgaaa gcaggggaag acagccgttt gtttggttcg
    30421 atcccttcaa aacaaattgc tgaagggtta aacaaacaat acaaaatcaa attagataaa
    30481 cgaaaaatcg aattagaaaa tccgatccgt tcactaggct acacaaacgt acctgttaag
    30541 cttcatcatg aggtgacggc tacgatcaaa gttcatgtcg tacaagaata acaaatcttg
    30601 atagcgatgt tcagctggta agtataacca gaaggaaaaa agacaaaccg aaatttatct
    30661 gagaaaacag ctgcagcaat gaaagcaaaa gctgcaaatc gatttcagat tgatttcggt
    30721 ttcttttttg ggaacagcaa aatagcataa agaaaacgag tataataaaa gagaactatt
    30781 tttttattac actttcggta cgaatgatga cttttctctc attttcttgt aaaatgaagc
    30841 aattgaagac aaggagcgat acgtatgaat gaagtgtggc aggatcgaat cccaccgcaa
    30901 aatattgaag ctgaacaagc ggttttaggc tctgtttttc ttgacgcaga aacgatcatt
    30961 gatgccatgg agtacataga gccaaaagac ttttatcgtc gtggccatca aattattttt
    31021 gagacaatga tcgagttaaa tgatcgtaat gaagcgattg acgtggttac tgtcaaagac
    31081 cggctggaac aagccaattt gttagaagat gccggtggtt taagttatct ctcagacttg
    31141 gcattagcag ttccgacagc agcaaatatc gtctactatg cgaaaatcgt tgaagaaaaa
    31201 tcattgctgc gtacattgat ccagacagca acaggaatcg ttacgaaagg attcgagcaa
    31261 ggagaagaag ttcaaacaat tttagatgat gccgaacgca gtatcttgga ggtttcggaa
    31321 aaaagaaatc gaagcggctt tttatctatt gctgaagtac tgaactccac gattgaaaat
    31381 atcgatcgac tagctcaaaa caatgaagaa atcacaggtc taccaactgg ctatcaaggt
    31441 ctggataaaa tgacagcagg tttccagccc gaagaactaa tcattcttgc tgcacgtcca
    31501 gcggtaggta aaacagcgtt tgcattgaat attgctcaaa atgtaggaac aaaaacagat
    31561 cgttctgttg cgatatttag tttggaaatg ggggcagaat ctcttgtaaa tcggatgctt
    31621 tgtgcagaag gttcgattga ggccagccat ttacgtacag gtcagctttc ggaagaagaa
    31681 tggtcgaatc tgatcgttgc gatggggagt ctttctcgag caaatatttt tatcgatgat
    31741 acaccaggga tcaaaatctc tgaaatccgt gcgaaatgtc ggaaactagc gcaagaaaaa
    31801 ggcaatctag gcttgatatt gatcgattat ttgcagttga ttgaaggtaa cggtaaagag
    31861 aaccgtcaac aagaagtatc agatatctct cgccaactga aaaaactggc gaaagagctg
    31921 aaagtacctg tcattgctct ttcacagtta tctcgtggag tagaacagcg acaagacaaa
    31981 cgaccagtgc taagtgatat tcgtgaatcc ggatcaattg aacaagatgc ggacatcgta
    32041 gccttcttgt atcgagatga ttattatgaa agagaaggcg gagatgacga tgatggaaac
    32101 gagccaaaaa atgacaacgt catcgaagtc atcatcgaga agaaccgaag cggtgcacga
    32161 ggaacagttg aactactgtt tatcaaagaa tacaataagt tttcgtcgct ttcgccaaga
    32221 gaagaatttt aaagaagagg ttgtgagcct tgagcaatcc cgagagctct cgtaagaaga
    32281 tgcaaggagt aaccgcagga acgactagag tacttaattt aaacagatct ccaaagggat
    32341 tgtgacaaaa gtcttgtcac agtccctttt tccgaataaa cggtgttcaa tcagctgacc
    32401 cttggtatta gctcagcaaa cgtcaaaata tgaggaacta ttttgacgtt tgtttctcta
    32461 atactcaggt caaaacgctg atcttacgac ctcttttcct taaacggtgt tctcctgcca
    32521 actcctcggt cacaagtcac aatatcatca aacatgagaa gcagtttttt gaaattgctc
    32581 cttgtgactc agagttaaac ggcaggctca caacctcttt cttaaacggt gttcaaaagc
    32641 ttgcatctgc ggtaatacgc ccaatcaaac gaaaaatatg agaagctatt tttgtttggc
    32701 tgttcttatt acttgatgca ggacagcttt ttcacaacct ctgattcacg gtgttccaaa
    32761 agtagcttct tcgaaaaata agtcgaaatt tcacaaaaat ttgagaagca attttcgtac
    32821 attccttctt atttcttgaa gctgaccact tctgttacaa cctctttttt aataaccatt
    32881 ctaaaaagat aaagttcgtt ttttaagcgt ttttataaaa taaaaataaa aatcattcga
    32941 ttttatttga aatatgtatc tattattgat acaatggttc aggattaaat aatatagaac
    33001 gaggtgttca catgtcatct gtagtagtag taggtacgca atggggcgat gaagggaaag
    33061 gaaaaatcac agactttctc agtgaaaatg ctgaagtgat tgcacggtac caaggtggcg
    33121 acaatgcagg gcacacaatt aagtttaacg gtgtgactta taaactgcat ttgattcctt
    33181 ctgggatttt ttataaagac aagatcagtg tgatcggaaa cggcgttgta gtcaatccta
    33241 aatcattggt taaagaatta gcttatttac atgaaaaagg tgtagaaaca agtaatttgc
    33301 gtatttctga ccgcgcgcac gtaatcttgc cttatcatat caaattggac caattacaag
    33361 aagatgctaa gggcgaaaat aagattggta caacgattaa aggaatcgga cctgcctata
    33421 tggataaagc agctcgtgta ggtatccgta ttgcagactt attagataaa gaaatttttg
    33481 aagaacgtct tcgtttgaat ctagatgaca aaaaccgtca atttgtaaaa atgtttgatt
    33541 cagaaccact tgattttgac gatatttttg aagaatatta tgaatacgga caacaaatca
    33601 aacaatacgt cacagatact tccgttatct tgaatgatgc tttggatgca ggcaaacgcg
    33661 tgttgtttga aggcgcacaa ggtgtaatgc tggatatcga ccagggaact tatccttttg
    33721 ttacttcttc taacccagta gccggtgggg taacaatcgg aagcggtgta gggccttcaa
    33781 aaatcaataa agttgtcggc gtctgcaaag cctatacgtc acgtgtcggt gatggaccat
    33841 ttccaactga attatttgat gaaacaggag aacaaatccg cgaagtagga cgagaatacg
    33901 gtacgacaac tggtcgtccg cgtcgtgtag gctggtttga ttctgtagtt atgcgccatt
    33961 ctaaacgagt ttcaggtatt accaacctat ctttaaactc gatcgatgta ttaagtggat
    34021 tggaaacagt aaaaatttgt acggcttatg aattagatgg cgaactaatc taccactatc
    34081 cagcaagctt gaaagagttg aaccgctgca aaccaatcta tgaagaattg ccaggctggt
    34141 cagaagacat tacaggatgc aaaacacttg cagaactgcc agaaaacgca cgtaactatg
    34201 tacgtcgtat ctcagagctt gttggtgtac gtatctcaac attttctgtc ggacctgata
    34261 gaacacaaac aaacatctta gaaagcgtct gggcgcaaat ctaaggataa aaacgacgac
    34321 tgaatcagga cgttcttacc agagcgagtc gaagtgttta tctatacgat aataataact
    34381 tgaagaggta gtgaaagaga cgtttagcct tattgccgat aggctgtctc ttgaacactg
    34441 tttattcaga ataagggact gtgacaaaaa ccgtgtcaca gtcccttttt ccgaa
//
LOCUS       DACGLI010000033        33950 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.034, whole genome shotgun sequence.
ACCESSION   DACGLI010000033 DACGLI010000000
VERSION     DACGLI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.034"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..1152
                     /locus_tag="IXT22_001650"
     CDS             <1..1152
                     /locus_tag="IXT22_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863019.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="IXT22_001651"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="IXT22_001651"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAQ4863020.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="IXT22_001652"
     CDS             2728..3003
                     /locus_tag="IXT22_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAQ4863021.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="IXT22_001653"
     CDS             3009..3776
                     /locus_tag="IXT22_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAQ4863022.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="IXT22_001654"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="IXT22_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAQ4863023.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="IXT22_001655"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="IXT22_001655"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAQ4863024.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="IXT22_001656"
     CDS             7920..8222
                     /locus_tag="IXT22_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAQ4863025.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="IXT22_001657"
     CDS             8225..9388
                     /locus_tag="IXT22_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4863026.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKNFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="IXT22_001658"
     CDS             9414..12842
                     /locus_tag="IXT22_001658"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAQ4863027.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="IXT22_001659"
     CDS             12863..13987
                     /locus_tag="IXT22_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863028.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="IXT22_001660"
     CDS             13977..14414
                     /locus_tag="IXT22_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4863029.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRVVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="IXT22_001661"
     CDS             14398..14736
                     /locus_tag="IXT22_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAQ4863030.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="IXT22_001662"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="IXT22_001662"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAQ4863031.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="IXT22_001663"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="IXT22_001663"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAQ4863032.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="IXT22_001664"
     CDS             15893..16936
                     /locus_tag="IXT22_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4863033.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="IXT22_001665"
     CDS             17095..17823
                     /locus_tag="IXT22_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAQ4863034.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="IXT22_001666"
     CDS             17939..18184
                     /locus_tag="IXT22_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4863035.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="IXT22_001667"
     CDS             18181..18399
                     /locus_tag="IXT22_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAQ4863036.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="IXT22_001668"
     CDS             18535..19074
                     /locus_tag="IXT22_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAQ4863037.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="IXT22_001669"
     CDS             19067..21340
                     /locus_tag="IXT22_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAQ4863038.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="IXT22_001670"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="IXT22_001670"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAQ4863039.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="IXT22_001671"
     CDS             complement(22513..22767)
                     /locus_tag="IXT22_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAQ4863040.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="IXT22_001672"
     CDS             complement(23167..23436)
                     /locus_tag="IXT22_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863041.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="IXT22_001673"
     CDS             complement(23906..24361)
                     /locus_tag="IXT22_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAQ4863042.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="IXT22_001674"
     CDS             complement(24499..26427)
                     /locus_tag="IXT22_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4863043.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="IXT22_001675"
     CDS             complement(26624..27457)
                     /locus_tag="IXT22_001675"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAQ4863044.1"
                     /translation="MFFANIIKAVILGIIEGITEWVPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="IXT22_001676"
     CDS             complement(27649..28353)
                     /locus_tag="IXT22_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4863045.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="IXT22_001677"
     CDS             complement(28376..29002)
                     /locus_tag="IXT22_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4863046.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="IXT22_001678"
     CDS             29328..31703
                     /locus_tag="IXT22_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAQ4863047.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="IXT22_001679"
     CDS             complement(31727..32218)
                     /locus_tag="IXT22_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAQ4863048.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="IXT22_001680"
     CDS             32405..33325
                     /locus_tag="IXT22_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4863049.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="IXT22_001681"
     CDS             33479..33823
                     /locus_tag="IXT22_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAQ4863050.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT        11256 a         5933 c         7038 g         9723 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa aattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agttgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttatttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcacccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgttcaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt
//
LOCUS       DACGLI010000034        33575 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.035, whole genome shotgun sequence.
ACCESSION   DACGLI010000034 DACGLI010000000
VERSION     DACGLI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.035"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..1032)
                     /locus_tag="IXT22_001682"
     CDS             complement(<1..1032)
                     /locus_tag="IXT22_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863051.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVL"
     gene            complement(1061..1378)
                     /locus_tag="IXT22_001683"
     CDS             complement(1061..1378)
                     /locus_tag="IXT22_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4863052.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(1404..1724)
                     /locus_tag="IXT22_001684"
     CDS             complement(1404..1724)
                     /locus_tag="IXT22_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863053.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(2188..3603)
                     /locus_tag="IXT22_001685"
     CDS             complement(2188..3603)
                     /locus_tag="IXT22_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4863054.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(3620..4936)
                     /locus_tag="IXT22_001686"
     CDS             complement(3620..4936)
                     /locus_tag="IXT22_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863055.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(5086..5784)
                     /locus_tag="IXT22_001687"
     CDS             complement(5086..5784)
                     /locus_tag="IXT22_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAQ4863056.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(6073..7062)
                     /locus_tag="IXT22_001688"
     CDS             complement(6073..7062)
                     /locus_tag="IXT22_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAQ4863057.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(7142..7975)
                     /gene="msrA"
                     /locus_tag="IXT22_001689"
     CDS             complement(7142..7975)
                     /gene="msrA"
                     /locus_tag="IXT22_001689"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4863058.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(8150..9784)
                     /locus_tag="IXT22_001690"
     CDS             complement(8150..9784)
                     /locus_tag="IXT22_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863059.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(9771..11618)
                     /locus_tag="IXT22_001691"
     CDS             complement(9771..11618)
                     /locus_tag="IXT22_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863060.1"
                     /translation="MFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKDNSSILKI
                     ELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRIKGLSS
                     IFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNICTILI
                     SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAYGLI
                     FNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVVNLV
                     KAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTM
                     GLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWR
                     ILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQSKHG
                     HIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNI
                     TYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKY
                     TPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            11605..13242
                     /locus_tag="IXT22_001692"
     CDS             11605..13242
                     /locus_tag="IXT22_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4863061.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(13387..14127)
                     /gene="truA"
                     /locus_tag="IXT22_001693"
     CDS             complement(13387..14127)
                     /gene="truA"
                     /locus_tag="IXT22_001693"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4863062.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(14318..14953)
                     /locus_tag="IXT22_001694"
     CDS             complement(14318..14953)
                     /locus_tag="IXT22_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4863063.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(15100..16341)
                     /gene="sstT"
                     /locus_tag="IXT22_001695"
     CDS             complement(15100..16341)
                     /gene="sstT"
                     /locus_tag="IXT22_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAQ4863064.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            16539..17537
                     /locus_tag="IXT22_001696"
     CDS             16539..17537
                     /locus_tag="IXT22_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863065.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            17550..19568
                     /locus_tag="IXT22_001697"
     CDS             17550..19568
                     /locus_tag="IXT22_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAQ4863066.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(19628..20344)
                     /locus_tag="IXT22_001698"
                     /pseudo
     CDS             complement(19628..20344)
                     /locus_tag="IXT22_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
     gene            complement(20571..21113)
                     /locus_tag="IXT22_001699"
     CDS             complement(20571..21113)
                     /locus_tag="IXT22_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4863067.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(21118..21345)
                     /locus_tag="IXT22_001700"
     CDS             complement(21118..21345)
                     /locus_tag="IXT22_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAQ4863068.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(21424..23304)
                     /locus_tag="IXT22_001701"
     CDS             complement(21424..23304)
                     /locus_tag="IXT22_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4863069.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(23493..24107)
                     /locus_tag="IXT22_001702"
     CDS             complement(23493..24107)
                     /locus_tag="IXT22_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863070.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            24249..24809
                     /locus_tag="IXT22_001703"
     CDS             24249..24809
                     /locus_tag="IXT22_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4863071.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(25129..25428)
                     /locus_tag="IXT22_001704"
                     /pseudo
     CDS             complement(25129..25428)
                     /locus_tag="IXT22_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(25682..27317)
                     /locus_tag="IXT22_001705"
                     /pseudo
     CDS             complement(25682..27317)
                     /locus_tag="IXT22_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27872..28435)
                     /locus_tag="IXT22_001706"
     CDS             complement(27872..28435)
                     /locus_tag="IXT22_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4863072.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLVDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(28450..29493)
                     /locus_tag="IXT22_001707"
     CDS             complement(28450..29493)
                     /locus_tag="IXT22_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863073.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(29626..30030)
                     /locus_tag="IXT22_001708"
     CDS             complement(29626..30030)
                     /locus_tag="IXT22_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4863074.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(30263..30898)
                     /locus_tag="IXT22_001709"
     CDS             complement(30263..30898)
                     /locus_tag="IXT22_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4863075.1"
                     /translation="MIFLQKYGFYFLLLGVMSDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILVVATVGLYGIGDCIFT
                     GLFSINTNESSCNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(31164..32216)
                     /locus_tag="IXT22_001710"
     CDS             complement(31164..32216)
                     /locus_tag="IXT22_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863076.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(32229..33167)
                     /locus_tag="IXT22_001711"
     CDS             complement(32229..33167)
                     /locus_tag="IXT22_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4863077.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
BASE COUNT        10560 a         6610 c         5290 g        11115 t
ORIGIN      
        1 taagaccatt ggtgtcaaaa taaatggaat gaacatgatc gggttcaaca cgataggtaa
       61 cccaaacatc gttggttcat taatattgaa gacacctggc gcaatcgaca agtttgttac
      121 aaccatatat ggtttgtttt tacgtcctac taaataaata gctaacagta aacctaaagt
      181 tgcacctgtt cctcctaagt tgacaaagct gtcaaagaaa ggtttgttca cgataaacgg
      241 tgcgctatgt ccagctgcga ttgcattaac gtttgcttca atggctggcg cattgattgt
      301 ttgcatcaaa ggatcgacca tattcgctcc gtgtaaacca aagaaccata agaatggtgt
      361 gataaatgca agcagtaagg cagatggata agagtttgca agtcccataa atggttcttg
      421 gaccactgta tagaaagaac ctacgatatc atcaacaccg aatgcagcaa aaattgcagc
      481 aactaaagca aacgcagaga tagtgatcat tgctggtagt aatgaagcaa atgcttttgc
      541 aactgccggt ggcacaccat caggcatttt gatgatcaat ttttcatttc cgcttaaacg
      601 tacaaagatt tctgttgaaa taatcccaac aataatagca ataaacaaac cgtttgagct
      661 catacctaat gctccgccta aagcgaagaa agagcctaaa gaaatcacac ctgcggaaac
      721 accgtctttt cggtagccgt tagctaaatg ataagcaagc aagaaagcaa tcaagacaga
      781 aagaatggca aatgtaccgt tccaagcagc agccccgaat cctttccatg attcaccacc
      841 aaaaattgag ttcatcaatt cttggaaccc gggaatcggt aagttattga tcattactgc
      901 taatgctcct aagatcatta acggcatact caccataaat gagtcccgaa tcgcaactaa
      961 atgccgttgt gcaccaattt ttgatgctac aggtataaaa tgtttctcca taaatgcaac
     1021 aaatttatcc ataaatcttc cctcttttct ttactgtaga ttacgcgttc aatcgacgat
     1081 acagatcaat gatctctttt gctaaatctg taaaagctat agatgtcatc agatgatctt
     1141 gactgtggac cgtcaaaagc gtgacttcaa cgtgatttcc ttgtgcttct tgtgtcagca
     1201 tctctgtttg agagtgatgt gcttggacta aagattcctc tgcatctttg attttttcat
     1261 ctgctaaagt gaaatcacct tttttcgcag cagcaatcgc ttccattgca tcgctttttg
     1321 catttccgcc aaacatgatc agacccatga tggcttctag atttttttga tcttccattt
     1381 attgtatcct ccgataattt ttattatttg tttattagtt tttctgcttg gtcgagtact
     1441 ttttcaccat tcatcatgcc atagtcagcc atattgatta catctaaagg aatgccttta
     1501 ggtgctagct tttcagcaaa ttgattttgc ataaagcgta cttgcggtcc taaaagtaaa
     1561 acgtctacat ttttagattc tagttgatta tccgcatctg aagcagatac agcaaagatg
     1621 tctgcttcca ttccttttgc ttctgctgcc ttttgcattt ttgtgactag gagacttgta
     1681 ctcattccag ctgaacatac aagcatgatt gttttctttt ccattttaaa cacgttcctt
     1741 tctatactta cacttgtata taagcaagta gcgtgccaac tttaaaagcg ctttaaaaag
     1801 ttgatatcat cacatttaag gtctatacca agttgcatac acactaaaaa agaaagcgca
     1861 cactaaacac acaaattaat ttttattacc ttttttcttt taacgtgcac aaaaaaagtt
     1921 gtgacacaaa acttgtcaca acttttttca aataaacggt attcaaaagc ttgcatctgc
     1981 ggtaataagt ccaaccaagt taaaaacata agatgttgtt tttactttgc tattcttatt
     2041 acttgatgca ggacagcttt ttcacaacct ctcaataaac ggtgttcaat cagctgaccc
     2101 tgggtattag ctcaaaacgc tggattcaca acctctttta tttcaaataa ccagtaaata
     2161 caatgaacat ctacaaaaaa cttctattta tttatagatt tcgtcaggca aatccaattc
     2221 tctcttatca atcaaagtct gataccacga agcagatttt ttcaatgttc tgcttcgttc
     2281 atcgttcaat tcgattcgaa ctaatccata tcgattctta aatgcattca ttggtgacac
     2341 acagtcagtg aatgcccata acatatagcc ttcgcaattt gcgccttctt ctgttgcttt
     2401 gatcaagtaa tgcaaatgct gtccgataaa ttcgatacgg taatcatctt gcacgattcc
     2461 tttctcatcc atatactgtt cttcatattc tcttcccata ccgttttctg ttatcagcca
     2521 agggatatta tgataatttt cttttagata catggctata tcatacatga ttttcggata
     2581 gatttcccat cccctggaat tattcatttt cttcccaggt aaatcaaaga cttcataata
     2641 tcgttcagga tggaaaggtg tctcttcatt ccattgataa cgaggggcgc gaacgcgttt
     2701 aggataatat tgattgattc caaggaaatc tactgtatga tgctgaatcg tttctaaatc
     2761 ctctgttgca ggatcgaaat aaatcgattg tttttgacac aactccagga actcttctgt
     2821 gtagtatcct tttaccatcg gatcaaaaaa tactcgatta taaaacaaat catacatata
     2881 agcagctttt tggtcttctg gagaattgga tcgagcatag accatttcag gatttaaaat
     2941 acagccaatc cttccaccat aatttccgct gcggtaaatc tctactgctt tagccgttgc
     3001 taaaacttta tgataattcc acatcatcca cttttttgtg ttttgttcat gcggccagcg
     3061 aacagcatcc aaatagcaac gcgtttgggg aacgattggt tcgttgaatg taaaccagtt
     3121 ttttacccta tcaccgtaac gatcaaaggc aatttgagca tacttagcat aaaaatcaac
     3181 tacttttctt gaagaccagc catcatattt ttccaaaaga aaagctggga cttcataatg
     3241 ttccaaacaa atcatcggtt ctacgtctgc ttcgatcaaa gagtcgatca tttcacttat
     3301 atgctgagca tattcttcat ctactataca gttctcataa tcagtaaaaa aacgagccca
     3361 attgatagaa gtccgataat gtgtcagatg gatggatttc atcagatcca catcctgctg
     3421 gtattgttcc ataaaattag ttgctacggc tgggccatac ccattatgcc aaacaaaatg
     3481 ttcattttta taccagctat ctataaacga atcctgtcct tctttttttc ctttccaacc
     3541 ttccgtttgc caagcagaag atgcagcacc aagaataaaa ttttttggaa tagtaatttt
     3601 catgatttcc tcctgttttt tagatcccat cattttccac acgatttgct acttttacaa
     3661 atggcagata gatcaaaata gaaacaataa tacaaacaag ttgcgtaata actgcaccga
     3721 tatttcctgc tgttgccaga taagcattga cgatcggcgg cattggccaa gggaccatta
     3781 caactgcttt cgccgcaaat cctaaagcgg ttgcaaaata accaatcgtt ccagtgataa
     3841 gaggcgttaa gataaacgga atagctaaaa ttggattcag catgatcggc ataccaaaaa
     3901 taactggttc attgatgttg aagatcccag gagcaaggga taacttggtg atttgtttca
     3961 tatcttcccg ttttccaact aacaatactg caatcagtaa accgatcgtg actccagacc
     4021 cgcccatact catatacata tcccaaaatg gcatagtaat aatgttcggt acttcttttc
     4081 cagcttcaaa agcttccgta tttacagcaa ttgccgctaa aagcaacggt tcccgtatcg
     4141 gcttcaccat ttgatttcca tggataccaa tcacccaaaa gacttgcgca ataaacatca
     4201 atagcaaaat acccggtaac ccttgtacga caccttctaa tgggcgttgt acgacattgt
     4261 aaatgatatc ataaaggtac attcctgtaa gttctttgat gataaatccc gcagccgcga
     4321 tacccgatac agtcagaatc gtcgggaata aagcagaaaa actagcagaa acattcgttg
     4381 gcacggtatc aggcattctc agctgtagtt tcttctgttt cctcaaccag caataaagtt
     4441 caatagaaag gatggagacc aacattccca aaaataaccc tttcgtatct gtatattgtt
     4501 tagccaatac gttttctact ataacagtct gattttcatt cactaattca taaacagttg
     4561 gattaacaga taaataagac atcactgcga tgataccagg gaatacacca tccactttat
     4621 tcagcttggc taattcgatc cctatcagaa aaacagcata gatggtcaag aaacttagtg
     4681 tgacatagct gatggcagat gcgataggct ttaattcttc taaaaaacgc aagaaactta
     4741 tctgtgctaa gccattttcc gagtcaaaga ccattgctga aaacaatgtg ccaaaagcac
     4801 ccgtaataat taccggaatc aatgcagcaa atgcgttttt tatcaccatg atatacctta
     4861 aattattgat tctcgttgcc acgttcccta aaacattggc taatttatcc ataaaactca
     4921 ttccagatcc cctcattcct gcttcttctc cttgacgtca tctctttttg tctattagtc
     4981 agcgcttaca tttcgatgaa cagaaactat ttactcctct tttttaccaa atataaaaca
     5041 aaaattcatc tgatgtattt atcataaaat acatcagatg aactgtcaat tagtttcttt
     5101 ttctcctatt attttctgta attctctccg atttattgcc atatggacag tcattgcatc
     5161 aaacgcagca agtgcattcc gcctttcgat ggcctgaacg atctctgtat gaatatcgat
     5221 cgtctcgatt ttcagatgct ggatatcata atttttatta aacaaagcaa ttgattcatt
     5281 aatgattggg ataatatgca gcaaggctac gtttccgcta gcttctgcaa tcatcgtatg
     5341 aaaatcgatg tctaattgaa catgttcttg tgtgccttct cgaaaagaag tttcaatctt
     5401 ttgcgttaat tttttcattt ggacgatttg attcttcgtt gcatattccg ctgccaaacc
     5461 tgccatctta ggctccaata aatatctcag ttcaaataag tctcgtatca tccgatcctg
     5521 atcttcaatc aaagaaaaac cgagtgggtc attggcaatc cctcgcttat cactgacaaa
     5581 tgtccccgct ccttgccgaa cttcaaggat attcctggaa gctagagccc gcacagcttc
     5641 tcgcaccgtg cttcgcccca cctctaaata atcggacaat tcatattcat tcggcagttt
     5701 atctcctact tgcaactgca tttcctttaa atatctaagg atcttgtcag tagttacttc
     5761 tactagggtt ttattttctt ccaaaccaca tacctccttt tcatctgatg tattttttcg
     5821 taattattat aacacgtttg aatcatctga tgattttttg tatacaaaat tgattaatcc
     5881 gttcatagac atacaaacga agaagatatt taccataaaa aagactagga taaaattcac
     5941 tcctagcctt cgatcatttt tattttgaac gacaaaaaat atgatgttca ataacagacg
     6001 atcttcattc gattcttgat gtcatctttt gtttttttta atatatggat aaaaagtttg
     6061 attacatcgt ttctattcta gaatttggtc gattctcaat tcttcttctg gtgagaaatc
     6121 taaattatcc atcattcgaa cactttcttg taactgactt aaccgacttg ctccgaccag
     6181 tacacttgta acagattttt gtcgcaaatt ccatgcaagg gccatttgcg ctaatgattg
     6241 tcctcgtgat acggcgattg tttgcagtgc tttgattttt tccagagttg atccaacttg
     6301 ttcttctgaa aggaatggta tttccttacg atgtgctcta gaatcttcag gaataccatg
     6361 tagataacga tttgtcagca acccttgagc aagcggactg aacgtgattg cccctagccc
     6421 ttcttcttct aatactggag atagatcgtc ttctagtagt gcacgagaaa acatattgta
     6481 gcgcatctga tgaataatga acggtgcttc ctttcttttt aaaatttcag tcattttttt
     6541 tgtatcttct ccattatagt tggatatacc aatatataat gcttttcctt gtcttacaag
     6601 ttgcatcaaa gcttctgctg tttcttccaa aggtgtatca gggtctgggc gatgatgata
     6661 gaagatgtca acataatcta gccccattct ttggagactt tggtcacaac ttgaaatgat
     6721 ggatttacga gagccccatt ccccatatgg cccttcccac atatgataac ctgctttgct
     6781 agaaataatc agttcatcac ggtaggcttg aaaatcttct ctaaaaatac gcccaaagtt
     6841 tttctctgca gctccagcag ggcctccata attattcgca aggtcgaaat gggtaattcc
     6901 catgtcgaat gcgcctctta aaatctctct ttgattatgg ataggatcat aatcaccaaa
     6961 attttgccat aatccgagag ataaaatcgg taatttcaaa cctgaatgac cggatttacg
     7021 atattccatt ttttcataac gtgcactatc tgcaatatac aatttttctc ctcctcatca
     7081 aatcttttta aaacgctttc ttttttctat ttttagttta ctacatttta aagaaaagga
     7141 gttaatcaaa atgatttttt cgtatatttt tttgccattt gttttttact cgttgataga
     7201 tcagaaattg attacgtgct tgctggattt ttttataacg tttcggttgt tttttgtaaa
     7261 attgctgatg atagttttct gctggccaaa acgtaccggc tggttcgatt tttgtgacga
     7321 ttggttggtg gaaagttcct gaactgtcta gtttctgttt tgattgttcc gctaattctt
     7381 tttgtcgttc gacttgataa aaaatcactg gacgatattg cttccctcta tcttgaaatt
     7441 gtccaaatgt atctgtggga tcagtaattt gccaatagat tgtcagcaac tcgctataac
     7501 ttatttctct tgtgtcataa atgatctcca cagcttccac atgacctgtg taaccaccac
     7561 ttacttgatc ataatttggt ttttcaacat gtccgcccgt gtatcctgac aaaacagata
     7621 ggatcccttt tttcgattca aacggctcga ccatacacca gaaacatccc cctgcaaata
     7681 ctgcacgttc ttgatagtca gcatcttgca tggcatgctt ggaaaagtca tatttttgct
     7741 ccttatcaaa tccttccgta atcaataaat aaaagtccat tacatcaggc gtcagattca
     7801 ttcggatagc taatggacgt agtgttgctt ctagttttga taactgttct ttaacggata
     7861 tattttctct tatgtcattc tttgtctgaa tcaatacttt tcgttcccaa tctcgtgtat
     7921 tcggattcaa aatcagatta taaagtgttt gaatgaatat ttgttcctca tccatagatt
     7981 ctcctccttt ccgaagaaga caagctagtg actttagctg taatttatca taaagtgagg
     8041 aaataagcga ttacttcatc cccctacaga tttttcgtat aaaaaagaga gaatccttat
     8101 cgacagattc tcctttttaa tcaatttatt ttataaatga aaagttaatt taccttttat
     8161 ggaaaactat tttaaaaaat aaacataaat atgcagttaa tgtaacaaga taagaaataa
     8221 tagtcgttac tgtataactt gtgcttactt taatatcagc aactcctttg actccgctta
     8281 tttgtaccaa tccattagca ttcacctgct cctttacagg ttgatgattt atttctacat
     8341 tcgttcctaa ataagcatat acaggaagtg tgattacttg gctcttctca ttagttactc
     8401 tatatatgat agaactacca gttgttttat aaggaaggtt tacccattga ctgccaatct
     8461 ttgcttcgtg ttttattata tgctccttat tctccaatga agcgatagga gaataatcat
     8521 ataaaaaata atccattcct ttagtggtat acgcctctac tgtttctttg tttacaacaa
     8581 tatgtcccgg ctgagaaatt attttttgat tgaaattttt tttactagaa acagttaaag
     8641 tgattaataa caaaacagtc ataaataaat aaaatagttc tcttgtctta ttgtatcttc
     8701 tatttttgaa aaatatcatc gttaatatca gagaagagaa tattatttgc aagcttaaga
     8761 tccgccaagg aaattgtaac aatttggctg gcgtattttg cagaagatac catggcacca
     8821 aactagttgt agctagccaa gtcaaacacg taccataata aatctttttt tctatgtttg
     8881 ttaatttttt aaataaaatc aggggaatac ataaagataa cagaccaact agtcccattg
     8941 agtaagtagt taagtcgttg ttcatagctt cagtcagact atcgaacaca ttagatgcat
     9001 gagcatataa atttgtcacg ctaggtttgt tgattttttg gtagagcatt tgttcaaaca
     9061 tcggatacca aaaagcactc gtcagaacca atgtcattcc tgccgcacta aataattttt
     9121 taaatatagc aataaaatct gcattcttga aacctttaga aaccaaacga ataaaaataa
     9181 aaatgataat taatgctgta ctcattaatg ttgatagtac atggctgtac actagcaaac
     9241 tcatactcaa tgctagcttt acagacggat acttttcttc ttttccagag atgatttgat
     9301 aagcataaaa taatacaggg ataacaagtg ttattgcgat agcttcggca attgcggaac
     9361 gatagtagat gtctactgtc cgataagcag agaaaatata gagacaacta aataaaaatg
     9421 ccgctttttt ttgttttaaa aaccgctcgc cataatgata agctacgagt gttgtacaca
     9481 agttcaataa ccaaacgtaa ataatatagc ttacaatcaa attttttgtc atccaatata
     9541 acattacagc tggaaaaaaa gtcagaaagg gataaaaata atttacacca tatccagtat
     9601 aattgaatgt ctcataatta atcggactgg taaaaatagt cgataacccc ttgattcgag
     9661 ataagtgaaa agaaagatct ccagtggtat aaatactctg tgtatttttg aaaaagatga
     9721 aagaatatat actactaact ataattaatc cactcaatat tactactttt ttatttattt
     9781 tcattcttct tgtttatctc ctttttagtc acatatcgag aatctttcaa cttattaggt
     9841 gcaaatcgtt taaaacttga atacaccact aaacaataag tcagaatact gatccataaa
     9901 gccatgagag cagttggagt atattttgtt gtaatttcta tcttattttc tccagcattt
     9961 acatccacat tcactaagcc atgtttttta taagagtcat ttacgacttt accgtttact
    10021 tttacctgtg tacctaaata agcatatact ggtactgtca ctttttgctt tttgttgctt
    10081 gccactgtgt aagtaatgtt attatctgca gctttatact tccctttttc ccacgattct
    10141 cctactttta cttcatgttt ttctaagtga ggcctttctt ttatcgcttc tgttggggcg
    10201 taatcgtata atcctcccat atctgatgtt gtataacgtg ggagtgtttc ttcattgata
    10261 acaatatgac cgtgttttga ttggataact tttgcgtaat tttcttttgc tgctatagac
    10321 gtgacgagta gaaacaccac agtagcgcca atgattaacc atgaatattt tttattcata
    10381 gtctttttca taaaaacaag cgttatgatc attgaagaaa aaaagatttg gatacctaag
    10441 atacgccaag gaaactggag taagcttatc ggtgtttttt gaaacaaaaa ccatggaaat
    10501 aaattagtta cgcataccca tgtagaaact acgccaacat agatgatttt ttcttttttc
    10561 tccatttctt tcagtatgaa taaaggaaaa atcaacgcaa ccaatcctaa taaccccata
    10621 gtgtatgttg taatatcgtt atttaacgct tgaatgatac tatctgaaat agaaagtgct
    10681 tctagctgca aatctgtttt gaagggactg tgtatttctt gataattcat ctgctgcaac
    10741 ataggatacc aaaaatagct agttaatgca caagtcaaaa aaacagcctt tactaaattc
    10801 acgaccacaa attttatatc gttttttatt tgcttgctta aaaacaaacg aactataatc
    10861 atacaagcaa tcaatgcact acacaatagt gtagttaaga catgagtata cacaagtaga
    10921 cttatactga cagataaagc gatgactttt ttttctctat tgaatatcaa tccataagca
    10981 taatataaaa cagctgggat aatcgtaaga gcgattgctt ctgcaattgc ggatcgataa
    11041 tagatatcaa ctgttcgata agttgcaaaa gtatataaac aactaaataa aaaagcagca
    11101 tctatctttt taaaaaactt ttctccataa taaaaactaa tcagaatcgt acaaatattt
    11161 aataaccaaa tatatagaac ataacttaat attaagttat ttgaaattcc ataaaaaacg
    11221 actgcaggaa ttattgtaag aaaaggataa aaatagttca gtccatctcc ataattgtta
    11281 aatgttgtat agttgattgg cccttcaaaa atagaagata accctttgat tcgtgaaaga
    11341 tgaaaagata aatcacctgt tgtataaatt tcttgagcat ttctcataaa atttactgaa
    11401 tataaagtac taagtaagat aagaactact aaaagaaatg cttttttact tattttcata
    11461 gatttgttgt tctccttttt taattctatt ttcagtatac tagaattgtc tttttttaat
    11521 aagttttgcg ttaaattttt catagcacta gtatgatata ctagaaaaga atcaattttt
    11581 attactttta aataggagaa aaaaatgaaa aaaaacaaaa accaaataat agatatcatt
    11641 tttatgttat ttctaagttt tgcttacgtc atccctctat tcatgtctaa gggaatctat
    11701 catagtgtca atcaggatac ttactttcat ttatctcgaa tcataggact agataatgta
    11761 tggagttctc cagtaaactt caataacttc gatcatcatg gaacaatgat gaatattttt
    11821 tatccatggc ttactcttta tccagctttt ttattttata aaatgatggg aaatcttgtt
    11881 ttaagttata atatctacta tttttttatc acttttttaa caatggtcgt ttcttatttt
    11941 tctatgaaac aaataaaaaa caatcgttat atttcgctgt tattttcgat tatttataca
    12001 ttttccgcct atcgtgccat tgacatattc catcgtgctt cattgggaga agctgtcgct
    12061 ttaacatttt tgcctttgat actaatgggg tgttacgaaa tttatattag agattaccaa
    12121 aaatggtact ggttgtctat tggcatgacg ctagtagtgt atactcattt actttctgtc
    12181 gctatggttt ctgtatttat tggaggaacg ttgtttcttt ctttttattt ttgggaccaa
    12241 aaaatcgcta gactcttaag tcttttaaaa gctaccgtcc tcaccttttt tttaagtgcg
    12301 ggattcttaa ttccttttat tcaacaatct agagcacaag aattgaaagt cccactggga
    12361 aaagaattaa gtggtatggc tcctagtgat atgctgacac atattttaaa taataactat
    12421 aacaactata ctattggatt attcttattt ctcggattga ttggtgcttt tatttttata
    12481 aaaaaattaa ctgctgatga tttatttatt ttctttcttg gtgtatttgt tcttttttgt
    12541 tcaaccaatt tatttccttg gcaacttttt aaccatacac cagttaagag tctacaattt
    12601 gtctggcggt taaatggttt ttcttcttta tttatagcct atacgatgag tatagtgatc
    12661 tattatattt tttctactaa aaataattca tggaaaataa tggtctttac gtttcttgca
    12721 ctaatattgc atctctcagg agtaagcaat tctatccatg ctaacaaaga ttcattaaca
    12781 cttatagcac ctgaagacgc tgttgctata gctgaaaatt acaatcatac tgattatgca
    12841 aacaaagagt caatctatca tcctgatatg attaataatg atcaatattt actaggtaac
    12901 caggaaataa atccaacaac tcattttatg agtaacaaac ttacaattga attagataat
    12961 tcgaataata aaaatactgt cttgacgaca cctatttatc gttataaagg gcaagtggct
    13021 tctattaatg gcaaactagt acaaacaaaa ttatctaagt ttggcacaac tgaattaact
    13081 attcctccag gtataaataa agtcgttatt acttatcagt acacaaaact agcaattgct
    13141 tcaagatatt tatctatcgt tactttgatt ttatttttac tttatcgatt tactttttct
    13201 aaacaaaaac aaccgagaag agaagtacaa cattctcact agatttttat ttaagaaaga
    13261 ctttttagct gtacacataa acaggctaaa aagtcttttt ttatatttct ttaatttgct
    13321 tcatacatta tttaacatcg atatttatac tgtgaaacat gcgtttcatc cattatcaaa
    13381 gtatttttat cgataataaa cttcatccaa aaacagacct tgtgcaggga cggtttctcc
    13441 tgcatgttgc cgcactttgc tttcaaatat ttcatcgatt gtttctatcg gcatggcacc
    13501 tgtgccgatt tctagtaatg tccccatgat aatccgcacc attttatata agaatccgtc
    13561 tccgacaaaa gtaaaatgaa gcatttctcc ctttcgttcg atagataatt catcaatcgt
    13621 acgcactgtg gatttttttg attttttcaa tgcagaaaaa ccaatgaaat catgtgtacc
    13681 cactaatttt tcgcaagctg cattcagctt gtccatatcc aactcttgag ggaaataaaa
    13741 gctgtggttt cgctcaaatg ctgaaggaat cacgttgttc caaacataat agctgtattt
    13801 tttgcccacc gcattatatc ttgaatggaa gcgctcaggc atttcttcga ttcttttgat
    13861 gacaatatcc cgcggaaggt aacgattcat aaagtcgatc atttctgcca gtccaatttc
    13921 tgtgtttgtt ttaaaatttg ctacttgtcc tcgcgcatgg gtgccagcat ctgttcttcc
    13981 tgatccaata atttctatct cttcatttgt catctgatgc aatacttttt cgatttttcc
    14041 ttgaatggtt ttatcgtcat ctccaagtct ttgccatcct gaatatcttt ttccgtcata
    14101 ttcgattgtc aacttgatgt ttctcatatt ttagtggctc ctctgtcttc catttggtct
    14161 tctctctacc tttttaagat tgtagcacaa aatatagctc cttgcttctc taagacagaa
    14221 gctatacaag aaaactgtgg aaatatatat ttcagaaaaa caaaaaacag ccaccggatg
    14281 aagtatccgc tgactgttca atttgacggc tcaagtttta ctgtttgaga tgcaagatac
    14341 tcaaccaggc aatgggcaca taattaaaga aaaaactgat tctttggcaa aaacctattt
    14401 tattcagtaa tggccaagaa tttatagaag gaattcttgc cagtccataa atcgccgcaa
    14461 aaagcaaact gatcacagac agtccaaggt ataagtggct tacgtccatt tgcccatttt
    14521 ttcgatagat caagaaaaga agaactggaa acaataaaaa accactgtaa cctaaacctg
    14581 atccgatatt atggacccat gtcgagacat tccacgaaga ttcatgggta ttgatactga
    14641 acaaacctgt aaagatacaa tcacctatac catagaacgc gatggctgct gtaactaggg
    14701 tagctaacac acgagatgta ctaacaaatg cagcatacaa tgcaggcaat gacaggatga
    14761 aaaagatccc tgaaaccaca gaccaaataa gaaacgcttt tcttacagga ctggaaacct
    14821 ctccaaatac actgatcacg ctcttcattt gatctaattc aggataatac aatcctaata
    14881 cgtacggagt caaaaaatca ctcagcacgc ctaataataa aaagaaaaaa ccaaatttac
    14941 gtaaaaaatc catgatacgc ctccaataac aattacctat gcttttaatt gttattataa
    15001 acgactttat cttgatttaa cagaaacctc tatttacacg aacatctata taactcatta
    15061 aaaactcgaa tcattttaaa aatactaaat atctaacgtt caacgttcac ttaatccatc
    15121 taaacaatct ttcaatttga ttttttcccc acttctttta cgcgcgccta gctctcctat
    15181 tgcagtaaac aacagatcac ttgacgaatt taaggcagtt tccattgaat cctggataac
    15241 accgataata aatccaatac cgacgatttg catcgcgaca tcattagaga taccaaacaa
    15301 actacatgct aatggaatca ataacagtga accgcccgca acacctgaag ctccacaagc
    15361 agctaaagca gacaaaatac ataaaaggac tttcaaaaca aaaggtgctt caatccctaa
    15421 agaatgtaca gcagtcaacg tcatcaagga aatggtaatc gcggcaccgc ccatattgat
    15481 cgtagcacct aacgggatcg atatggaata agactctttt gtcaatttca atctttcagc
    15541 caacatcatg tttatcggga tatttgcggc agaacttcgg gtaaagaaag cgggaagtgc
    15601 gctttctttc aaacaaaaga aaatcaatgg atagggattt tctttaataa acaaaaacgt
    15661 gaggaatggg tacacaacta atgcgacaaa cagcatcgta ccgatcaaaa caagtaaaag
    15721 ctgcagatac tctgccaatc cagcgattcc agtcgtagca attgattgat aaaccaatcc
    15781 taaaatccct atcggagcaa atgcaataat cacttgtacg acttgtgaca acgctataga
    15841 tatctgatcc accaactctt ttgtcgattc tgaacgtgct cgaaaagcta gtcccaacaa
    15901 tacagcccag aataagacgc caaggtaatt cgcatcaata agagattgaa caggattttg
    15961 tgtgacattc gtcaacatag tagataaaac actttccaaa ctttgcggtg ctttttcaga
    16021 tactgtttct tgtaaagtaa taggaacagt aaaaattgaa cttacaataa ctgctacaag
    16081 tgcagaaagc aatgttccca ctaaatataa gatcaaaata ggcttcacga atgtcttatt
    16141 cccaatttta tgcttggcaa ttgacgccat cgtcaagaaa aaaaccagaa taggtgcgat
    16201 tgccttcaag caactgacaa acaacgttcc caatattgaa ataaatgtcc atgtggggaa
    16261 aaagatacca aacaatattc cgactaaaat accaacaaca atacgttgaa ctaacgacat
    16321 atccaaaaac ttctctaaca aatgaccacc ctttcacaat tttaacaatc attgtatcat
    16381 tttatgcaaa gaaactaaag gtataatttt ctaaaaattc taacaataca aacaaccatt
    16441 tcttgctaat tttgtacttt ttctgtctac acgttgtttt ttgagatatt ctaagttagg
    16501 atgttattaa tgggcaactt atcaggaaac gttttcttat gtttttgtcc aatttttttg
    16561 tgaggtgttt attcttgaaa aaaataaaga aggagagtta tggcttcctg acaatctttg
    16621 tcgcttgtat aatgatggtt ttacagcgta tattgatttc agcagtcact attcctacat
    16681 atgcaacaaa ccctggtcga ttctacatct atacattttt acaaacttcc gttgttattg
    16741 gtgcaaattt gatcccactt tacatgggtt accaatatca aaaaatcgcc cgtttaaaag
    16801 ttttacatta tttaagtcgt tttgccttta tattcctaat agccacacta gtttgcaata
    16861 tcttttttta cgtacaagct ggcagcttga atattcgtga ttattggctt atcctaacac
    16921 ctatcagtca gaattacttt acttatgctg tttcttgtac tttgcttttt tgtagtattc
    16981 cttatacagt tggattttta aataaattat cgaaaacaac aattaaatat ctactattat
    17041 ttttaacaat tggattagtt ggctgctcta ctctatttaa taaagacccg tttgcattac
    17101 agaatggaca gagtatttta tggatttttt atttattttt aatgggttat ggtttgaaag
    17161 aatggaactg gaaagaaaag gtccgctata agcttcctca agtatttatc agcttgattg
    17221 ttttattcgg tttgattatt ttgatgacac aaatttcact catcatcaga ggaaatacag
    17281 atacagcgct gaggttttct aaaccatatt ctctcttcgc aatgtattat actttctctt
    17341 cgtttttatt tttagaaatg ctatctgata aattaggtat aaaaggaaga ggaaattttc
    17401 ttgctgtatt tttgattgtc actcaagtta tatgtaattt ccctttagtt tcttatcgcg
    17461 tatctacatt tatgaaacgt gaatttccaa actcagggaa ggcatggctg ataaatatcg
    17521 ggcagttttt tatttgatat ttattagcag tgtccctcct agttatcttt ttattttata
    17581 tacaaaaaat ccgtttcatt catcgtttca tcgaatactt cgcttttgat tcgattgaac
    17641 aattaactca gcgttggaaa aaaagaattc attggctttt tgttcataaa agttattttt
    17701 tagttgcagc atttttttac tgctttacct tcgtgcagat tttcgtttta gaaccaaaag
    17761 aaggttggaa agaaactatc caggttgcct taaaaatatt tactcagcga caagcaccca
    17821 tgatcctgac aatcatcatt attatgggat ttttcttctt actattgttg atttccaatc
    17881 gtttttggta cgccttgact gctaccttga tcattaactt actgctcact atttcgacag
    17941 taatcaaaat ggaaatgcgg gaagagcctg tctttccttc agatttaaaa atgctgaccg
    18001 gattgtcaga actattatcg atggttagcc cagtcttatt aatcgtgggc ggattgatcc
    18061 ttctcctatt attgattact agtattattg tacaacgtag actacaaaaa cagtattcct
    18121 tgaagattca ttggaaacgt cgatttatca gtatcgctgt attattagga tgtttttcgg
    18181 gtgtcttttt cattaatcac aaaaattcgc cttctttctt gctgtttaat ttatttaaag
    18241 taaacaagac tttctttaac cagcaaggcg ccgtaaaaga taacggacca gtcattcaat
    18301 tcctaaacaa tatcgacatt aaaatcatgg aagaacctgc tggctattcg aaagaaaaaa
    18361 ttaatggaat aatgaaaaag tacaacacaa aggcagatga aatcaaccaa acaagaagtg
    18421 actggttaaa caatcagacg atcgttctca atttaagtga aagcttcagt gatcctgcac
    18481 gtgtccctaa tctgacagta cctacagacc ctattcctta catcaaaagc attataacag
    18541 aaggaacagg aggattgatg ttatccgtcg gttatggtgg cggaacagct aacatggaat
    18601 gggaaggact gacaggcttg agtatcagta acctgtctgc ttcgttagtt acaccttata
    18661 cccagctagt ggagcgtcag aaaataagtc caaatattac cgatctattc gatgaaaaaa
    18721 tagccatcca tccttttaca gctgctcttt atcgcagaaa acaagtgttt gataaatttg
    18781 gttttgacag gttctattat ttagacagtc cggataaatt aacttatacg gataaaatag
    18841 aacaaagccc acgcatatcg gatgattcag catacaaaga aaccttgaaa gctttacaaa
    18901 gcaatacgga aacgtcacaa ttcatccaat tatccactat gcaaaaccat atgccttatg
    18961 atgattacta tagtgaattg aactacactg ctgaaggaac tgctgtcatt cctaatagaa
    19021 gaaaagaatt acaaacttat atgcaaggcc ttcactatac cgatacagca gtaaaaaaat
    19081 tcatccaaga aatcgacaaa atcgataaac cgattacctt tgttttttat ggtgaccatt
    19141 tacccgcaat ctatagtggg aatgattcga aaaaatatgg attagaacag caccagacag
    19201 attatttcat ttataacaac aagtatagtc gtgaacaagc agctacgtta aataaagaag
    19261 ttgttgctcc taataacttt ggtgctatgg ctcttgagca tgcgaatatc aaagtaactc
    19321 cttactatgc gttgttgaca gaagtatcta atcatctacc tgcattaaca attgatccta
    19381 cagaaagctt gtctaatcgt tttaatggaa aacaggtctt tgttacagag gatagtcaaa
    19441 ttatccaaga aaaaaattta actgagaaac aaaaagaaat tctagaagat tatcgtctga
    19501 tacaatatga tcttgttgca ggtaaccagt acagtgcaac atgggcgaca caaaaaataa
    19561 aagactaaca aataaactga gcaaggggtt gtgataaaag acatgtcaca accccttgtt
    19621 tatctcatta atttgcttgt ccataaacga tttgattaaa gccatttttc aattcattat
    19681 tcgctgtctc gttgaagtaa agataattat cgggattccc ctgattttgt tgtgtcacca
    19741 atacttttgg ctgattttgc tgaaacccga atagatagac gtgctttttc agttatggtt
    19801 ctgtctctgc atcggaatag acggctgtga tttgatagtc tgcttgacct gtcccacttt
    19861 ctgaccattc tgcagaaaca ggcactccac caatagccat cttccactcc ccgttcaaaa
    19921 tagcttgagg gactttaaga ccatataagt ccacactcat ttgattcgta taacttttgt
    19981 attgttgtcc cattgtttgg ccccatttgg tcataaatgc ctctaattgt gcggatttgt
    20041 ctgcattcca cagtgtttgt tcaacttgtt cgctgctttc tgaagaggaa gatgaagcct
    20101 ctacagaaga acttgaagta gatgtttgag ttgtttcagt cgttttggaa gactctgacg
    20161 aagtagaggt atctgctgtt tctgtacttg ctgcagttga cttgctctct gtgctagttg
    20221 ttgtagtagt tgcaactgtt gctttcgctg tttcttttgt tgattctttt ttcgattcat
    20281 tcccgttggt acaaccagct aacaaaaaag ctagaccaat tgttactaaa atcctttttt
    20341 tcaattaaaa aactcctttc gattactccc acttctttat tctatcaaat aagcaatgtg
    20401 attttattga tttttcgtat tttctcatca atctttcaaa tcttctaaaa actgagaagc
    20461 acccgctgat gttgtctgta atacatcagc gggtgcttct tttattttaa tcttcgtgat
    20521 tttccaattt acctcacgct ttatatttgt atttgaagaa acatagactt ttagtcatca
    20581 tcgtcttcct catccaaatc ttgtcggaca gtttttcctt ggagtctttg tacttggtag
    20641 atgatttctt tattgaaact taaaagttca acaagcaatt gttgcaagcc atatttttct
    20701 tctttttcag ctaatttgat tgcccgtgtg ataaagacat tttggaaatc aaaatctttt
    20761 gcaaagtttt ccaacattgt tgaggctggt aaatatttgt tttgaccatg ttcgtaaatt
    20821 tttccataac gcatgacttc ttctaaagta gacggaacga tttcattttc aatcactaac
    20881 tcatgagaga ttttattgaa ccatctcgct tcttgatcag catattctga aaaaagggta
    20941 cttaattctt gcgaagatgt acccaaaaca tacaattgtg cttggatcaa tttcatttct
    21001 tctaatttaa aatttgctaa tacatgcccc accatggcgc cagcagttgg tttatgatgg
    21061 tcgatatctg cttgttttgt ttcttgaaca aatttttctt ccactatatt cattgattta
    21121 cgcctctttt acttttgctg attggacttc ataacctaat ttttccacaa ctgcagctaa
    21181 ttgttcaggg tggacttcat ctggatcaaa gtttgctttg attttgctcg cattaaacaa
    21241 aactttcgta ttgcttaccc caggctgttg agaaaccgca tgttcgattt tttgcataca
    21301 gcttggacaa gctagtgtat ctaattgcat aataattttt ttcatcgtag ttcttccttc
    21361 ctttttcttg atagtcttat tctagattac agcttccata aaaaaattga ttcttatcaa
    21421 gttttacgat ttttcttctt tgctttcgtg tccaaaatac aataaacgca tcgcgttaaa
    21481 gataacgatc aagatactag cttcgtgaac gaacatccca ctagccatgt aaataaaccc
    21541 ggcaaataag ccgttgagta aaaataagac gacaccaatg gcaatcacta cattttcacg
    21601 ggtatttaaa acagttttct tagccaagcg gtaggcatga accaacgatt caaaattaga
    21661 ttgcatcaag acaacgtcac tcgtttcgat agcaacatcc gttcctgatc ccatagcaat
    21721 cccgatatca gccgcagcca aagagggaga atcattgatt ccatctccaa taaaagcaac
    21781 gcgcaatcct tgttcttggt attttttcac aaattgaacc ttttcgtctg gtaataattc
    21841 agcatggact tcatcaatgc ctaacatatc agctacataa tcagcagtca tctgattatc
    21901 acctgtcagc atcactaact gttttgctcc tgcttgtttc aacttagcta attgttcagc
    21961 gacttctggt cgaatcacat ctgacacacc tatgatttga gtgatttttt tgtcgattgc
    22021 tacaataatg accgagctgc ctgtttgttg taattgatgt aaatcttgta cttgctttgg
    22081 tgtgagagaa agtttgtgag cggcaatcaa tttggtgttg cccgcacaaa ctgtatgacc
    22141 atcaatctca gctgtgattc cttgtccctt gattgtctga ttatctttga ctgctaattg
    22201 ttgaaaatca atgtctttct cctgagcata atggatcacg gcgcgcccca gaggatgatc
    22261 ggataacgtt tctaatcgag ccactaaagc taagctgtcc ccttcatcct ctgtatagtt
    22321 cttgatagtg gatacagcag tagttccttt ggtcaatgta ccagttttat caaagacaaa
    22381 agtatcgatt ttggaaaaag tatccattgc ttcaccgcct ttgactaaga tgccccgttt
    22441 cgctccatta ccgattcctg ctacattcga aacaggcgca ccaatgacta aagcgccagg
    22501 acaaccaaga accaaaacag tgattgctaa acgaaaatca cgactaatca gaccaacaac
    22561 caacgcaata agtaaaacgg ttggagtata atactgagaa aatcgatcaa tgaatttttc
    22621 cgcatgggat ttggtatctt gtgcttcttc tactaattcg ataattttgg caaaggtcgt
    22681 atcatctccg accttagttg cttcaatcgt cacgtagcca tctgctaaaa tcgttccaga
    22741 gaagacttca tctccactga ttttgacgac ttgtcgtgat tcaccagtca ctgcggcttc
    22801 atccgcatac cctttcccgt caatgactcg tccgtccaca ggaatagctc caccagtttt
    22861 tactaagacg atatcgcctt cttccacgtc atcgatttcc acttcttcag tcgttccatc
    22921 ttcttggaca acactagcag tagatggggc catctcggtc aaagccttga ttgactcccg
    22981 cgttttggtc aatgtttttt gttccagata gctaccaaac aaaaacaaga atgtaacgat
    23041 agctgactcc ttgtattctc cgatcataaa ggcaccaagc acagcaatag taacgagtaa
    23101 atcaattgag ataactttga ctttcactgc ctgatacgca tggatcataa taggtatgac
    23161 cgcaataata gaagctatgg ctagagcaat gttatagaac aagacaaaac cagtaaattt
    23221 tccgataaaa ccaaaaataa tcaacacagc tgataaggcg gtgatatgat ttcgatgctc
    23281 ttggatccac ttttgtaatt tcatctttct ccctcttttc ctttcattct tacgagacta
    23341 agtatagata cttatccatc ataaaaaatt gaccactatc aagtttagtc aaaaaggcgg
    23401 ttttcttttg gtagaataca ctacaaaaaa tagttagcaa gaagactcac taaaagtgat
    23461 cttgccaact attgtcgttt ctatcgaaat tttcattgaa tgattttcct gtacagcata
    23521 catcggagat ctatttcttt atctaagatt tttatcttgc taattttttc ctttagtctt
    23581 tcaaatccac gtcgttcata gaattgatac gtacagccac tatctgtaaa aaggaatatt
    23641 tcttttcctt tctctctttt ttcaaattct gttagcaact tggtaccgat gccttttgtt
    23701 ttcaaatcag gatttgcagc taaaaaaatg atctctccat ctggcgaatg cttctttaaa
    23761 tatgctgcaa gcatttgttc atttgctgtc tcgtaagctc ctttactttc tttagcaaat
    23821 atattttgta aaaaatcgaa tatcttaaca tatatttgct gtccaaaaga acgatgtttc
    23881 tttttttctc cttttatctc cgccagcaaa acacctgcca actcgtcctc tgcatacaaa
    23941 gcaagaattt gagttgctcg attcaactcc atatacaaaa aatatcttcc gtaaagattc
    24001 agcagaagtt cattttccat atatctctca aagttcattc cttcaacagc aaaatagata
    24061 gcttttttgt aatctttctt ttctaagggt ttaaaagtta gtttcatcat ttcgcctcct
    24121 caacttcaat gattgtgtta tacttacatt ataatagaca cagtgtctac tatctataat
    24181 caatcatcta taagtttgtc gattaagcga cagctttgct ttgatatgtc ggataaggag
    24241 ataggtaaat gaaaaagaca gatagacgcg tcaaaaaaac agaaaaagct ttggctgaaa
    24301 cactatccac attattagta aataaaaaga ttcaagcaat cactatacgc gaactaacag
    24361 aaacggcaga tgtacatcgt tcgacttttt atacacatta taaggatatc tatgatctat
    24421 atgatcaatt agaaagcaac ttttttcggg atctaaatga aattctctct tatgatccag
    24481 cccatagcta tgaggaacta tacactcgct tgattgacta tgtttacgca aatacttttt
    24541 tatatcgctt atttatcctc aaccatggtg atatttcgtt tcagaagaaa gttaaacaag
    24601 ttattgaaga aaactatctg aacatatggc tatatgaaga caagaaaacg attatcacag
    24661 aagaaatgag attctttact acgtaccacg tccaaggttg tctatccgtt ctcaatcggt
    24721 gggtagaaag caattacaag tactccaaaa aagaattatt agaactctta cagaaactga
    24781 atgatcacat agagaaaatc atgccttgaa taaaaacata ctaagcttag ttaagaagaa
    24841 ccgtaacctt ctcgtataac aactgaatct tatttagcca aattgtttac tgaagatttt
    24901 ttgagtaaaa tttctataat tcctacttat tgaaaagtag tttgtagtgc tgcttctccc
    24961 tctctaagtg atatatcttg ttgtaccaat caaattcacc tcatcattaa taaattactt
    25021 ttaggctaat ttattacaac ttataggttg aagctgtaac caatttatag tcatattata
    25081 tttttatcat ccagtttatt gaattcttct cgtttacctc aattcatttt aaaggggaat
    25141 cagctcatca tctaacattt tacgccatgc tcgcttcatt tcttgtgggt atttaaatgg
    25201 tttcgcttct ggatgtttgg ctttatatcc ttcgtaatcc ttactgttga taattgcttt
    25261 catattagga attggatctt cacctggcat atattgcaga ttagaagcat gtaatttttt
    25321 ctcagaaaca aaccactcat tggaaaagac atgaatcaaa tcatcactta cttgtgtaaa
    25381 atagcgacgt ttaatgacaa agatatcttc attgctatct agtgtacctt catttctttg
    25441 tgcttaaatt caaagataat tttctcaata aagatttttg attccagtaa gattccttta
    25501 ctccttttac aacatagcgt tgtcctttgt tttgaaacat cttcttcccc tctttgccat
    25561 taaaaatagc ccaattctct ataaagaaga ttaagcttca ttattataat ataaagttta
    25621 aatttggttt attacttact ttttcttatt ctctagtaag ctaatattga aaaaaatgta
    25681 atcagatcat tatttttata tgttgtaact tcctgataag aaaactaatt aaaagaaaga
    25741 ggtaactaca taaactaatt aaaaaagcta acttcatagt tggaggataa atggaagaaa
    25801 cttcaatgat tgtttctcct tgtgttcctt caatcgacac tagtcctatt atcaatctct
    25861 cttttttgtc catttacttt tgcgactgtt ccccaataat caaatacagg aagcgttatt
    25921 ttttgtcctt tagattcatg tactgtatag actattttcg aatccatcac ttgataaggc
    25981 atagtatgcc attccttgcc aattcttact tcatgattct gcaaatgttc tttgtattgt
    26041 aatgcttccg tgggtgcata gtcataaagt cctccgggaa ggagtgtcgt gtaacgaata
    26101 agattttctt gattcattac caagtgatct ctctgagtga caactttatg ttcatagttt
    26161 gcttttgttg cagcagatac agccaacagt aataaaacaa ttgccgttat attaactact
    26221 tttctttgct tagctgatgt gctcttcatg aaaacgaacg ataaaatcaa cgagccaaac
    26281 agtacttgaa agcctaagat tcgccaagga aattgaatca tttgaatggg tgtattttgt
    26341 aataaagacc atggaaaaaa tttggtggat aagagccaag agactaccgc actaaggtaa
    26401 atcacttttt ctttgcgatt aaatccttta aaaaagaaga gtggacagat caaagaaata
    26461 ataccaatga ttcctaccgt aaaggttgtc aggtcattat tcatcgcacc aatcaaacta
    26521 tccgagacat ttaatgcttg gtgttgtaag gtcgttttat ctggctcatt aatcgattga
    26581 accatgattt gtcggaacat cggataccaa aagtatgctg ttaaaagaat cgtcattcct
    26641 actgcctttg acaactccac aatcaaccgg atgctttctt tttttcttgt ttcacttact
    26701 acaaagccgc ctaagactag taagccaacg gctattacac tcataaaagt ggaaagaaca
    26761 tgtgtataaa tgagtaagct catactgact gctaatggaa ttgcacatgg ctttttctca
    26821 taaatcagtg cgtaagcata atacataact atcggtataa ccgtaagtgc aatcgcttca
    26881 gcaatagcag aacgatgata aatatcaatc gtacggtacc cataaaatgt atataaacag
    26941 ctaaatataa aagccgcatc gattcttttt aaaaatttta gtccataatg aaacatcagc
    27001 atgatagtac aaacattcaa tagccaaaca tataagatat aactaacgat taaattatta
    27061 cttatccaat aaaaaatgac tgccggaaaa aaggtcaagt agggataaaa ataattcact
    27121 ccgctcccat aatgattaaa cgtcgtaaaa ttgattggac cagaaaaaat tgaagataac
    27181 cctttgactc tagcaaaatg gaaggcaata tcccccgatg tagaaatagt atgaacattt
    27241 ctaaaataat tgattgaata aagtccagca ataattgcta ggagaatgga caatattatt
    27301 tttttcttta cttgcattac ttaattatat actcctttca tggattgctt tatctagtat
    27361 aacttaaatt ttaaataaat cgttatttat ttttactctc acttaaaaaa gcactaaaat
    27421 tataagagag ggaggtaatg gtctgaacac caagaattgt tccaacatcg aattgcttaa
    27481 ctaatgagtt caaagcttaa ttatgtggct cttatattta ccgagcgtgg attgcgatct
    27541 ctttagcgaa acaaacatct ttcataaaaa aaacagccat atccgctttc ttggatatga
    27601 ctatttacta ctactttact atctttcatt cttcttgtct cacttatgat aaggcgctgc
    27661 gtatcatgag tgaatgatat taggaaaact tcataaaata aatcttttat acatttccac
    27721 ttctagatgg tcattcatgt tagaagaatc aaactatttt tttactgtcg taataatatt
    27781 aaaacactag aacaaatcaa ttaaattcca taaaatataa ataatagacc tagcatcatc
    27841 tggtataaaa tggatgctag gtccgttata tttactcaaa attgattcta cgaatagatc
    27901 ttcttatcat ttctatttta gtagtcatgc gttgttgttc ttctaaaggt ggtaatggta
    27961 taagtagttt agataaattt gtaccattta catttggttg cccagttccg taagaaattt
    28021 tttctaataa cttccaatat aatggcgagt ctaagaagca gtctacgtat tctgataata
    28081 atttctcaac taacctaatt cgaatcaagt aagaagcaaa aacagattcc tcacttattt
    28141 ccttaaccaa gaaacttttt cccatagttc ctcctgtcct tgctatcaaa atgtcatttt
    28201 cttccaatct taaatcaact agtttagaat tactaatatc acagtaaggc acactggacc
    28261 aatttacacg tccctcttgt atatctgtga ttctcaaaaa cttaacattg ccttgttttt
    28321 tcgccgaatc tgtatagcca tattgaatct tagtagaaat acttcctaaa taaacccata
    28381 gtcgaacatc gctagatgat ttttcttgtc gttctttatg aacaacagtg atcatcttga
    28441 gttgtccgac tattttttag ttgcagcaat ctttttggga cgcttatttg catgaagcaa
    28501 cgttgctaag tctagtaata aaacattggc taacacagga ttggctttct cgcgatacgc
    28561 tgcggcgcca ctttcaaaca atactgctag acgatcttct acaacaacga tttgttccaa
    28621 atacggtgga aatttgattc gttttaggat ccggctagga gagtcccgct cggacactaa
    28681 gagttccgag gtataaggac cataagaacg actggctaag agataatggc cataaaaagc
    28741 cacaccttga atcttatcag atgtttttct gctcattgtc acggttggtt ggattttgtc
    28801 tttgcggcga attgctgttt tcatttcagc tatcgtcggc aatagataga aagtcaactg
    28861 tccttcacct tttagtgtga agttgccaga taccagttga tcattgtttt gagtcaaata
    28921 cgatgcttgt ggaatctctg agagatcagt tgtcagccaa taagcgattg gctgtcccgt
    28981 ctcttcagat gtatctgcta agatatcgat caaacgtaaa gcggctactc gtccagtagc
    29041 agatcctgtg attgtcaacc ataaaagttc ccgttttgta tcatatacta agccccctac
    29101 atgtggccgt ttaggtaaaa tcagcagttt gatcggctgt cctgtttctc tatccagtac
    29161 atgaataata gaatgatgct gatggtcata gcagtaggca gaaataaaca caaaatcttg
    29221 agaaaaagcc aacccttgcg gcgtcatcca ttgacaaacc tcattttcgc cggtttccgg
    29281 caccaccatt cttgtttctg ttaatccagg aatgttatat tgttttgctt cagccttttc
    29341 ccaagctgct tgaacaatag gataccgttt taactttttt tcaatatcct gatgtatccg
    29401 ttgctgcttc caatgcttaa actttaggac atagtaaaca agaaggccaa tgaccagcaa
    29461 cactaaaatc attattgcta cccgctgtgt catttttttg cctccttgtt ctattcgatc
    29521 aatcgtccat ataccgctat taattaccgt aactacatgt ttcttttact agcgtttctt
    29581 tataggatct ttcataatct catttatagt aacattaaga atcccttatt ctactatagt
    29641 cacttccaca tcaatattgc ctcttgttgc tttagagtat gggcaaaatg cgtgggcttc
    29701 ttctgcgatt ttctctgctt ggtccttctc aagtcctggc aaagaaactt ctaaaacgac
    29761 cccgatttgg tagcccccat cttctaattg aaataaagat acccgtgctt tgacttcaga
    29821 atcagactca agattatttt cttccagcat gtgttgaacc gcgccgttga agcaagatgc
    29881 gtatccagcc gcaaaaagtt gttccggatt tgtcccttca ctatggattc ctgggcggtc
    29941 gatcttcatg tgcatacttc cgtttggtgc ctcaacttcg ccatcacggc ctccacgatt
    30001 gatcattgct gtttcgtaca tttttttcat tgagatcatc ctttctttcg tcgttctata
    30061 ttaagtgtaa cgagtatttt ttaatctgac aaaggtaatg cttgcattcg gcgacatcag
    30121 ttagacaaca tcgatgatca gtgatagaag cagtttatct atacaaaaaa agaagggttc
    30181 tatgatattt ggtgtcctta ctcgccttga gtaacaacac caaatatcat agaaccactt
    30241 aatcagcttc acactgcttt ttctactttc gtagttgaaa aaaacttaaa caaatcatcg
    30301 gcaaatagtt aaagaaaaaa cttaatcgtt gaaagaagcc caattgctta aagaaggcaa
    30361 actgactaat cgacggaatc cgtgctaatc cgtaaagacc tgcaattagt aaactaataa
    30421 ctgttaaaac aagataaaaa tggctaagcg taccttgacc actttgacga taaagcagaa
    30481 caagtaacaa tgggaaaagt agaaagcctg catagcctag cccagaacct atattatgga
    30541 tccaagtcga tagattacaa gagctttcat tcgtattgat actgaataag ccagtaaaaa
    30601 tacaatcacc tatcccatat aaaccaactg ttgcaacaac aagtattgca agtgtttttg
    30661 atgttccaac aaataggtga tacaacgcag gcaacgaaag aacaaaaaaa agtccagata
    30721 caactgacca gaccaagaaa gcacgtctga ctggactatc tacgtcacca aacacactaa
    30781 ttacggtagt catttgattc agtttgggat aaaaaaggcc aaggatatac ggtgtcgata
    30841 aatcactcat cacacctaat aataaaaaat aaaaaccata tttttgcaaa aaaatcattt
    30901 tcttccccta ctttttagtg attattcgat acatccaaca atcaaatttt ttctcatttt
    30961 aacacatatt tttattctag ttgtcttttg aacaatcaat aacataaagg tgagtttctt
    31021 ctacatttta aaaaatcgaa tggcactgaa gagttcagtt gtcagcatca atctcctact
    31081 caaaaaggca aaaaaacgta agtcagatgt tgttgacatc tcacttacgc atccattgat
    31141 tgaaaatttc ttagtaaaat ctactagcct aaaaatttga agacttcttc tcgatcatac
    31201 agtttaaata ctttctcgca taaaaattga gtaattagtg ccgcaaaaac agggatgact
    31261 aaccaacaaa gaacaacaag aaagccattt agccctgcat ctaaagaagc caacggacca
    31321 acaagtccga ccacgccgaa accagcagaa gcaggcgtac ctgaaataga aaatagagcg
    31381 acaggaatag ctgtaatcac tgcactaact aaacaaggaa taagaatcac aggttttcta
    31441 aatagattag gcatcatcat cttcatagcg cctaaagcaa tcgcaattgt cacacctgac
    31501 ttattaacct tccaagagtt cactactaaa acaaaagtgg ttgcagctac gcccatcgca
    31561 gccgcaccag cagaaacacc atctagttgg attgccattc cgattgctac tgttgaaata
    31621 ggagagataa tcaaaaaggc aaaggaacaa ccaatcaaga tagacattaa cagcggttgt
    31681 aaggtagtga agttattaat caatgatcca attgcagaag taattgctgt tacaaaaggg
    31741 aataaataaa aaccaagtaa acctgcacct acacctacaa caatcggtgt taacacaatc
    31801 gacactgacc caaaactatt tccaatcagt aaaatcagcc cgacagcaat cgatgctgtc
    31861 agcatcgtat taataatatc gcctgtacca gcaccaacgt aaacacccgt ttcacccaaa
    31921 tcaggtgtga atttgactac accagaacca acaaaagaag ctccggctac aaccatcatt
    31981 ctcatcggat caaatccaaa ttgtaaggca atcaaaccac caatgatcaa aggtgttgct
    32041 agttgaaaaa taactgctaa ctgtgcgatc gttaccgcaa agggatacgc actaaaatat
    32101 tttaaaatgg cacctaatac tgcattagga atcaatccaa taatgattcc tgttgctgta
    32161 ccagcgagga ctttattcag aaaaattttc ggtgatattt tttgtgaagt ttccattcaa
    32221 tctctccttt attttacgtt caaactatct tcttttgcat ggacaagctc agtcaagaaa
    32281 tcacaataag gcgtcgcaac accatatttc ttcccttttc tagaaattgc gccattgata
    32341 taatcgattt ctgttaatcg atggttctta atcaagtctt gatacattga aggataatgt
    32401 aacccaattg tttccgggtc aaaacaagat tcacaatgtg caatgacttc tgggacatct
    32461 agttcaatct tctctactgc tgctactttg gcaaactcat tgacaatcgt cgccaccatt
    32521 ttatgagcag tcgatgtttt tcctagctca gccatattaa cgtctaagat tgtgcatagt
    32581 ccgttcattg ttccgttcac acatgctttg cgataaatag aatagtgaat attgtcagaa
    32641 aaatgagcat ttaatcctga ttcagacaat ttgtctgcta atttttttgc agctgcttct
    32701 tttccatcac ctaaattttg taattctact gaaccacttc caaataattt gacctgacca
    32761 ggaccttcaa gacctgccgt ccacatggta tttccaatat agatattttc cattggtaca
    32821 aatttctcaa taatatcttc atgcccgata ccatttaata gacataagac ctctgtatct
    32881 tttttgatta atgattggat atcctgcagc attttttcca gctgcatcgc tttggtaaat
    32941 agaataatca gatcaacttg atcttctttt tctacttcgg attgaagaac gattggtagt
    33001 tttgcttcta cctctttacc attaaaattt gcttgtaatc catgttcttt gatttgttgg
    33061 acatgttctg cccagccatc gattaataat acttcgttcc cactttggtg aagcatcaac
    33121 ccaaagcgac ttcccattgc gccagcgcct gcaattgcta ttttcattga ttcttcctcc
    33181 tttttctttc tattatactc atttgagaat cttttcacaa cctcgttttg ttattcttct
    33241 cttatttatc atgtttatat ccaccattca agttatttta tcagcaaatc aataaaaact
    33301 ggaatagaat cccaatttca tcgtaagaga aactagacta gcaataagaa aatagaaaca
    33361 ttcatagaaa aaatctcact cctctgatta taaaagaggg ggcattaacc tcgtgtatac
    33421 taaaaccttc cattcattcg atggatgatt ttctttttgt gaaaaaatat tcattgtagt
    33481 acgatgttgc gcaacacaga cggatggtat tgcttattat ttattaaaat cgaacaatac
    33541 acttatttaa aaacttcttt cccagatttt cttcc
//
LOCUS       DACGLI010000035        32409 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.036, whole genome shotgun sequence.
ACCESSION   DACGLI010000035 DACGLI010000000
VERSION     DACGLI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.036"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            38..126
                     /locus_tag="IXT22_001712"
     tRNA            38..126
                     /locus_tag="IXT22_001712"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            141..212
                     /locus_tag="IXT22_001713"
     tRNA            141..212
                     /locus_tag="IXT22_001713"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:174..176,aa:Glu,seq:ttc)
     gene            228..300
                     /locus_tag="IXT22_001714"
     tRNA            228..300
                     /locus_tag="IXT22_001714"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Val,seq:tac)
     gene            310..382
                     /locus_tag="IXT22_001715"
     tRNA            310..382
                     /locus_tag="IXT22_001715"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:343..345,aa:Asp,seq:gtc)
     gene            418..493
                     /locus_tag="IXT22_001716"
     tRNA            418..493
                     /locus_tag="IXT22_001716"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Phe,seq:gaa)
     gene            495..575
                     /locus_tag="IXT22_001717"
     tRNA            495..575
                     /locus_tag="IXT22_001717"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Tyr,seq:gta)
     gene            582..655
                     /locus_tag="IXT22_001718"
     tRNA            582..655
                     /locus_tag="IXT22_001718"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:614..616,aa:Trp,seq:cca)
     gene            658..730
                     /locus_tag="IXT22_001719"
     tRNA            658..730
                     /locus_tag="IXT22_001719"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:His,seq:gtg)
     gene            742..813
                     /locus_tag="IXT22_001720"
     tRNA            742..813
                     /locus_tag="IXT22_001720"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Gln,seq:ttg)
     gene            859..929
                     /locus_tag="IXT22_001721"
     tRNA            859..929
                     /locus_tag="IXT22_001721"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:891..893,aa:Cys,seq:gca)
     gene            950..1034
                     /locus_tag="IXT22_001722"
     tRNA            950..1034
                     /locus_tag="IXT22_001722"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:984..986,aa:Leu,seq:caa)
     gene            1096..1168
                     /locus_tag="IXT22_001723"
     tRNA            1096..1168
                     /locus_tag="IXT22_001723"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1129..1131,aa:His,seq:gtg)
     gene            1178..1249
                     /locus_tag="IXT22_001724"
     tRNA            1178..1249
                     /locus_tag="IXT22_001724"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1210..1212,aa:Gln,seq:ttg)
     gene            1267..1351
                     /locus_tag="IXT22_001725"
     tRNA            1267..1351
                     /locus_tag="IXT22_001725"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Leu,seq:caa)
     gene            1606..2481
                     /locus_tag="IXT22_001726"
     CDS             1606..2481
                     /locus_tag="IXT22_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4863078.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2585..3349
                     /locus_tag="IXT22_001727"
     CDS             2585..3349
                     /locus_tag="IXT22_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAQ4863079.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3366..4778
                     /locus_tag="IXT22_001728"
     CDS             3366..4778
                     /locus_tag="IXT22_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4863080.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            4795..6119
                     /locus_tag="IXT22_001729"
                     /pseudo
     CDS             4795..6119
                     /locus_tag="IXT22_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            6132..6590
                     /locus_tag="IXT22_001730"
     CDS             6132..6590
                     /locus_tag="IXT22_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4863081.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            6882..8183
                     /locus_tag="IXT22_001731"
     CDS             6882..8183
                     /locus_tag="IXT22_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863082.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            8210..8470
                     /locus_tag="IXT22_001732"
     CDS             8210..8470
                     /locus_tag="IXT22_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4863083.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(9469..10704)
                     /locus_tag="IXT22_001733"
     CDS             complement(9469..10704)
                     /locus_tag="IXT22_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAQ4863084.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            11271..12098
                     /locus_tag="IXT22_001734"
     CDS             11271..12098
                     /locus_tag="IXT22_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863085.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            complement(12371..13141)
                     /locus_tag="IXT22_001735"
     CDS             complement(12371..13141)
                     /locus_tag="IXT22_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4863086.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            13359..14426
                     /gene="ulaG"
                     /locus_tag="IXT22_001736"
     CDS             13359..14426
                     /gene="ulaG"
                     /locus_tag="IXT22_001736"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAQ4863087.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            14444..14905
                     /locus_tag="IXT22_001737"
     CDS             14444..14905
                     /locus_tag="IXT22_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4863088.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            14925..16409
                     /locus_tag="IXT22_001738"
     CDS             14925..16409
                     /locus_tag="IXT22_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4863089.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            16452..16751
                     /locus_tag="IXT22_001739"
     CDS             16452..16751
                     /locus_tag="IXT22_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863090.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            16766..17404
                     /locus_tag="IXT22_001740"
     CDS             16766..17404
                     /locus_tag="IXT22_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAQ4863091.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            17409..18269
                     /locus_tag="IXT22_001741"
     CDS             17409..18269
                     /locus_tag="IXT22_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAQ4863092.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            18259..18969
                     /locus_tag="IXT22_001742"
     CDS             18259..18969
                     /locus_tag="IXT22_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4863093.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            19201..19635
                     /locus_tag="IXT22_001743"
     CDS             19201..19635
                     /locus_tag="IXT22_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863094.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(19732..20031)
                     /locus_tag="IXT22_001744"
     CDS             complement(19732..20031)
                     /locus_tag="IXT22_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863095.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(20300..20494)
                     /locus_tag="IXT22_001745"
     CDS             complement(20300..20494)
                     /locus_tag="IXT22_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863096.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            complement(20722..21483)
                     /locus_tag="IXT22_001746"
     CDS             complement(20722..21483)
                     /locus_tag="IXT22_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HAQ4863097.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            21803..22048
                     /locus_tag="IXT22_001747"
     CDS             21803..22048
                     /locus_tag="IXT22_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863098.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(22232..22981)
                     /locus_tag="IXT22_001748"
     CDS             complement(22232..22981)
                     /locus_tag="IXT22_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4863099.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            23167..23871
                     /locus_tag="IXT22_001749"
     CDS             23167..23871
                     /locus_tag="IXT22_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAQ4863100.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            23911..24468
                     /locus_tag="IXT22_001750"
     CDS             23911..24468
                     /locus_tag="IXT22_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4863101.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            24476..25615
                     /locus_tag="IXT22_001751"
     CDS             24476..25615
                     /locus_tag="IXT22_001751"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAQ4863102.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            25627..26058
                     /locus_tag="IXT22_001752"
     CDS             25627..26058
                     /locus_tag="IXT22_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4863103.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            26072..27517
                     /locus_tag="IXT22_001753"
     CDS             26072..27517
                     /locus_tag="IXT22_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HAQ4863104.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            27803..29428
                     /locus_tag="IXT22_001754"
     CDS             27803..29428
                     /locus_tag="IXT22_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4863105.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            30060..30413
                     /locus_tag="IXT22_001755"
     CDS             30060..30413
                     /locus_tag="IXT22_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863106.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
     gene            31194..>32409
                     /locus_tag="IXT22_001756"
     CDS             31194..>32409
                     /locus_tag="IXT22_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4863107.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELTFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT        10662 a         4940 c         6504 g        10303 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg caaactgtct caagggttcg aatcccttac
      121 tctccgtagc aaatttacct ggcccgttgg tcaagcggtt aagacaccgc cctttcacgg
      181 cggtaacacg ggttcgaatc ccgtacgggt cattttaatt gaatgttgga ggtttagctc
      241 agctgggaga gcatctgcct tacaagcaga gggtcagcgg ttcgatcccg ttaacctcca
      301 taatgaactg gttccgtggt gtaggggtta acatgcctgc ctgtcacgca ggagatcgcg
      361 ggttcgattc ccgtcggaac cgtcgttctt gttattcaat taataatttt aaaatatggc
      421 gcggtagctc agttggtaga gcaacggatt gaagctccgt gtgtcggcag ttcgattctg
      481 tcccgcgcca ccatggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc
      541 cttagggttc agtggttcga atccactctc ctccatttta taggggcata gtttaaaggt
      601 agaacagcgg tctccaaaac cgttagtgtg ggttcaattc ctgctgcccc tgccatggcg
      661 aatgtggcga agtggttaac gcaccggatt gtggctccgg cattcgtggg ttcgattccc
      721 atcattcgcc ctttttattc ttggggtata gccaagcggt aaggcaaggg actttgactc
      781 cctcatgcgt tggttcgaat ccagctaccc cagtttctat aatttattct ttattttgta
      841 gattgataat agtataatgg cggtatagcc aagtggtaag gcagaggtct gcaaaacctt
      901 catcaccggt tcaaatccgg ttaccgcctt agtactaata aatcaacttg ccggcgtggc
      961 ggaattggca gacgcgctgg actcaaaatc cagtgcccgt tgagggcgtg ccggttcgac
     1021 cccggccgcc ggtattgact aagatgtctt catcttagtt ttttattgag aaattaaata
     1081 acatctttta tgatggcgaa tgtggcgaag tggttaacgc accggattgt ggctccggca
     1141 ttcgtgggtt cgattcccat cattcgccct ttattcttgg ggtatagcca agcggtaagg
     1201 caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt tattattttt
     1261 aaatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgttga
     1321 ggacgtgccg gttcgacccc ggccgccggt ataattatca atatagcaac tttcttatag
     1381 agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc gatacaagta
     1441 ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt aaactatttt
     1501 tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg gttctttctt
     1561 aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa ggagtctgca
     1621 agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat gaaaaagctg
     1681 aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat ggggaaaggg
     1741 attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga caaattattt
     1801 gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca gattccaatc
     1861 gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat ctcctctcca
     1921 ttagattcaa atatctatat tacattgaca gatcatattt attttgctat tcaacgaaaa
     1981 agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct ttatccaaat
     2041 gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca aaccgagtta
     2101 gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct aggagagcct
     2161 aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc ccatctagaa
     2221 aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt aatggttcat
     2281 atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga aaatattggt
     2341 ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa gattaaagat
     2401 atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta tttggcaatt
     2461 catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa ccaaatgaca
     2521 catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa agaaggagaa
     2581 tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg gtgtgaatta
     2641 tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga tggcaaatat
     2701 gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag gtgtaggagt
     2761 ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc ttatcgaaag
     2821 cggagagttc agatccttat cttattatca gcatccattt aacattgaca aagatcaact
     2881 gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca taccaactca
     2941 tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag ttgttacatt
     3001 agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg aagttcgtca
     3061 tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa aaaaacgaca
     3121 aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga gagaagataa
     3181 aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa atggttcaag
     3241 ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat ttgctcaaaa
     3301 agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat agaggaggaa
     3361 taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta cttccagttg
     3421 cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg ctgaacatcc
     3481 cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta tttgctatag
     3541 gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt actggttttt
     3601 tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg aatatgggga
     3661 tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc tttaaagaac
     3721 aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg actatggtga
     3781 tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc atccaaattg
     3841 ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg gggatattta
     3901 tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat acgtatattt
     3961 attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga gagatgacac
     4021 gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt gtagtaatga
     4081 tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa gaaaataaag
     4141 agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca aatatcactg
     4201 agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc catgcacttt
     4261 ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt tttacattcg
     4321 gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct attttgattc
     4381 ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat ttgatcaata
     4441 agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat gaagtaacct
     4501 tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca acaaaaatgc
     4561 tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat acacgcctac
     4621 gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa ttagggataa
     4681 gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta gaagtgactt
     4741 atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat gatgatgaaa
     4801 aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat cgttcaagcc
     4861 attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga tattgatgaa
     4921 gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa ggtttttcaa
     4981 atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc gattttgttt
     5041 tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag attccactta
     5101 aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat gggatgcgct
     5161 caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc aaagcatgga
     5221 ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga
     5281 atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg attgcagtga
     5341 attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac cactttggct
     5401 ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag attattgaaa
     5461 aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa acttggcaaa
     5521 aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc ccgaataatt
     5581 acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa gagtatacac
     5641 gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct gataaaatac
     5701 gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga caatatatcg
     5761 tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta atcgttccta
     5821 atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg gcatatgttg
     5881 gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt cataaaggat
     5941 tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt gaaggttctt
     6001 atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc agagtcgcaa
     6061 aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca ttaaagtaga
     6121 ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta gctagtggtc
     6181 aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg ataggagttg
     6241 gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga ataatcgata
     6301 atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga aaaatactga
     6361 tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata cgggttgaaa
     6421 gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag aagttggagc
     6481 aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa ggaaatttat
     6541 taaaacaaaa ccaagaagta aagattaaag atagttgttt tgaattttag tgtacgatga
     6601 aaaaagttaa atagggtgat atttatgggt gaatttacaa aatttttttg aaatgataag
     6661 tttcaatcac tagatttaat cattttgatt tttgttaatt atcgaatttt tttgttgctc
     6721 ctatgattta gaaaacttat tttcaggatt cttaaaaata aatttgatta tttaagagaa
     6781 tatattgaaa taaaatttct taattatata attagttatg aacattcttt gcgttgtcat
     6841 gcaatgaatg gttcatattt tattgaaaag gagtggtttt agtggaaaag ctgatgaaat
     6901 gggtcgaaga gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt catttattag
     6961 caattcgtaa tggggttgtt tcaacattgt cattgatttt gattgggaca ttttttatgg
     7021 tctttatcaa tttaccgttt cctggatgga atgaatttat tgccccttat tcggcaacga
     7081 ttgttttacc ttttaggatg acgatgggat tgatggctat ttatgcaact tttgttatgg
     7141 gttcggatct agctaaatca tatggattag atagtgtgac aggtggtata ttatctttag
     7201 gaacgttctt tatgttacaa gttcctgtaa acgttttaac tcctgaaaag gcacctcttg
     7261 gctgggtctt acctatgagt tctttgggag catctgggat gtttgcgggg atcttatcta
     7321 tgatttttgc agtggaagta tatcgtttct ttaaaaatcg aaatattact atcaaaatgc
     7381 cagaacaagt gccacctgct gttgcccgta gttttgaggc attgattcca ggtgcagtca
     7441 ttttaacaat tacttggctg attcgaagcg tcgcgggctt tgatgtaaac gctaccttat
     7501 tatcgttatt cgagccttta accaatattt tagggaataa tttgcttggt gttttactac
     7561 caatgttttt gatccatttg ttgtggtcat ttggtatcca tggcatgagt attgtagggg
     7621 ctgttgttcg tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca ttggcagatg
     7681 gtacagctgc cacccaatta ccctatatcg ctcctgaaca gttttatcaa tggacggtaa
     7741 caattggtgg tgcaggagca acgatcgtgg tatctgtttt gtttatattc ttctgtaaat
     7801 caaaattctt gaaagaggtt ggtcgttttt ctattattcc tggtatcttc aatatcaatg
     7861 agcccatgat ttttggagct cctatgatgt tgaatcctta catgttcatc ccgttcaact
     7921 tagttccttt agttttgact attatcagtt attttgcagt caaattagaa atggtcaata
     7981 gatttactgt tttgccaact tggacattac cagctccaat cggcggttat ctttcagcag
     8041 gaaatgactg gcgtgttgtt atcttgatca tgatcaacac attgatagca tttattatct
     8101 attatccatt tgtaaaagct tatgataaaa agatgctgtc agatgaacaa agtcgtggag
     8161 aaaacgaagt ccaaactgtc taagtttggt ttttagaagg tgggaaacaa tgtattggct
     8221 gattttattt tttgttttta tctttttatt aacggctagt caccttatat tgaatatgct
     8281 agctacatat catattcaaa tcaatcgatg gatttgggca ctggcatcat ttttgatcgt
     8341 gattcttcca aagatcattg taccgcatat gaatgttttg ttttcatggg ggacatatgt
     8401 actttgtgga atttttgcta tcaattttat gatcgagcag catagatggt ttgtcacatc
     8461 gaagctttaa atgttctaaa agtggttgtg acagaagtgg ttagcttcaa gaaataagaa
     8521 gaaatttacg aaaattgctt cttaaatttt tgtgaaatgt tggcttattt ttcgtttggt
     8581 tgaacttatt accgcagatg caagcttttg accaccgttt attcggaata tgggactgtg
     8641 acaaggcttt tgtcacagcc cttttttaca taaagattat tattgtttta actgttttgg
     8701 cagaaagaag gaggcaaaaa tgaaaatttt atcagcaatg gattaagaat tagtcgatct
     8761 actaccaaag tgatcaaggc aaatatagat ttgggagctt acaaccatat agtaggggct
     8821 gcagtatggt gtatgaatgg taatatgtat gatgagagtg tttattcaaa tcatgaaacg
     8881 tgtatagaaa taattgcgct gggaatagca atcagtcatg gtgaacgtga cttttagttt
     8941 atcgttgctg acgacataga acattctgac atgatctact cagcatgtgg ggattgctgg
     9001 cagtttatat aggagtatgc atcggattgc gagatcattg tctcaacaga agagggaggt
     9061 tgattatcaa agataaagtg gtaaatccta catttgattt agtaattgtt gaagggacta
     9121 gcagcacaaa tctctacaaa gcgatgcttc tagatctata tgacacattt taagaaaatg
     9181 tatttgccta attattatgg tctttctttt gaagaaacgt tgagatgatc caaccagaga
     9241 aaggtgtcaa agaatttgac taagaataaa tggcagacgc tacctatgct catttggatt
     9301 gcgtcagatc ttttatttta aggatgattt tgtgtttttt agacaccgta atttaagtaa
     9361 ctctaacttt tcaatccact atttactttt tttgtatttt cactgtctgg gtctcgaata
     9421 gcgaaattac tgatgagtct ctattaaaaa agctttttct acttgaaact atattgggtg
     9481 gttgctcagg aaggtttcga tttcttgaat tgcttgttgt ggaccattta ttggaaaaac
     9541 ggcttgcagc gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc gcagagcaat
     9601 ctgcagtttt ctttcagtca ctggttttgt gagggcgatt gcgtttccgt attttacaca
     9661 atagtcaata ttacagcttt gctcaaattg catccccaca ccgataaacg gtttgccgga
     9721 ttcacaggca gtttggacgg tcccttcccc gccgtggata aaagaaaaat caatgaattc
     9781 atgcaaaaga tgactagaca gatattctgt tattaaaaga tcttctgagt cagattgaat
     9841 gtcatcaagc agatagtcaa taggtgcaat aaccgctaga tccggttgtt tttgtaagaa
     9901 gaacaaaatt ttgcgtaaca tacgcggatt gcctgaacta cccattgcga aatagataat
     9961 acgttttctt tcttgttgct ttcgctgtat aaaagttagc acttcttcag gcaaggaagt
    10021 actgagctta gcaaaaattg gaccaacgat tcgataattt tccggcagct gttcttcttc
    10081 caaaaatagt ttaggcgttg tgatgagatt tagatcagca tccatcattt gtaaacttgt
    10141 ttttggtaaa ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg ggatccatcg
    10201 ggtatttact atacgctttt ttgtccagtg ccaaagggga ttgcttaaag ggccgaagaa
    10261 acgtaactcg tggggcatca gcgcatgctc tgattgaaaa aaaggttcac tcaaagcata
    10321 gggtttaaca tatactaaag gaatcttttt attgcgggcc gataaaaaaa ttgtcacatt
    10381 cgaacctgtc acaatcagtc gaggctcaaa cttagcaatc agactctgtt cactagtgat
    10441 acgagaggca accatttctt tggtaaaagg gtttttaagt gtacgcaact ggtcaaattt
    10501 tatgatttgt tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat actcaaagcc
    10561 actttctgtg atcaaaggag caaaagtttt agaaaagcca aagaatacac agtaataacg
    10621 gtctttcata gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat tgaatactgc
    10681 aggagcaaaa agaattgtct tcatgaaatc ctccttattg gaatgagtct atcccttcgt
    10741 ttcttactag tatactaaaa aacacagcgt tcgagtagcc tatgtatatt ttgaatatta
    10801 aactgtctct cgctgttttc acaacttcta aatttaaatt ttgtaatcaa gttgaaactc
    10861 caattttcaa aaaaacacgc aacaattttt tgatcgattt atatgttgtg ccagataaat
    10921 acgagaagtt gtgtcattaa aaataaacat gagaacataa aaaataaaat aattatatta
    10981 attgataggt gtgctgtcgt cattatacac acgtaagaaa gaaatagtta tgtttaaaaa
    11041 tattcttaga ctttctcgcc atgacaattt tcactatgtg ttataactgt aaacgataat
    11101 tattcagata acacaaaaag aaatcaagga gcagatacgc cagttgttta atttgaatat
    11161 tattttaaaa ttaaaatttt tattctgttc taaacatttt tggttgttta gaactttttt
    11221 ttgtgtatga tataaaggag aaataatttt ttaaagggaa ggaaattgtt ttgattaaag
    11281 tagatggagc attactaaaa gaataccgaa agaaaaaggg gttaacacaa gtacaattag
    11341 cagaaggcat ttgtgaacaa gcaactgtca gcaatatcga aaacaagaat atgtcgccag
    11401 gcatcaatat cttaagtgcg ctttgcaaaa agctgaatgt cgagatctcc gatatattag
    11461 tagaaacaga agaagacaaa atcaggaaaa aaataaatga gattcaatca ttgaattctg
    11521 tatcaaaata ccaagaatct tataaaattt tacaaacgat cgatcaggaa aaagtaagta
    11581 attctgatct tttaaatcaa attttatttt atcaaggact gcttgatcat ctttatgcga
    11641 aaaaaccaga tgcagcatta ttttatttta atcaagtgtt ggaacaaacg accgaaacag
    11701 atatccatca cttacaagca gctgcaaacg tggcaatgat ctacttgtca aaaggagaat
    11761 tagattttgc gaaagtttat gtggagcgta cacttaaaat attgagtgag actgattttg
    11821 ataatctgat ggtctgcatt gtatattatg atatcgccac ctattaccgt aaaatcgagg
    11881 attatgataa agcaatccaa ttatgtgaga agggtattga gtataataag aaacataaat
    11941 cgacttatgc attggaatac ttgctttatg aaattgcttc ttgccataag caattaggag
    12001 aagatgatta tttagaaaga tatatggacg caaaaaaaat agcgcgtttc aacggaaatg
    12061 attacgcggt aaaggtgatt gaaaacgacc tgaaataaag tggttgtgaa atcagtgttc
    12121 tgatttgaat accgtttatt cgaaaaaagg aggtgtgact tttgtcatac ctcctttttt
    12181 cgatattgtt tgattcctat ttaggcaaca tataacggtt ataaaagaag caatagatta
    12241 tgatggtatc gattggatgg acacatcttg ggattccttt atcaatttga gcgtagcgtg
    12301 tttttcattt atcgataaat ttgttattca tttttttgat aatcctattt acatatttac
    12361 gtcctggttc ttaaaatgaa tctacttgaa tggtttttat ccccgtattt ctgatctcct
    12421 ctaatacttt ttcagaacaa aatttatcag tgatcaaata atcaaagact gaaatatcag
    12481 caatcttgaa ctttgatgtc agtccgattt ttcgatgatc agcgactaaa atcttacatt
    12541 tgattgtctt gttgaccatc atttcgttga tcgttgattc atttaatatc tttgttgtga
    12601 ccccatgtac tacatcgact ccgctacagc caatgataca aatgtctgca ttgactgaag
    12661 aaatcgtatt taatgcgatg tcgcccacta gtgcttcttt tggaaagcgc atctctccac
    12721 cagttaaaat ataactacaa ttatctttgt gcggagagta attgattttc acgttgtttg
    12781 taatgactgt caaatggtta gattgaagaa aatccagtgt tttcaacgca gtcgagctag
    12841 aattgataaa cagcgtatca taatcgttaa tgtatttact agcttctctg gcaatcgctt
    12901 gtttaatcct ttcaggacca gattgatcaa aatcagtctg gtttttgtaa ttataagaac
    12961 aataaccgta attgcgtatg atctcgtttt tttcttctaa taaatttaaa tctcttcgta
    13021 tcgtactaat agatacatca agggattcag ctaattcgaa agttgatagt tgttcagtct
    13081 gctgaagcag ttccaaaatt tctttttgac gtttttcaat attgacaagt gagtttttca
    13141 tgacttttgc ctcctgaggg acatcttgat ccatggattt atttgactag ttgttcattt
    13201 aaacattcat atctgtcttt attatactga aacaatcatt gattactgaa agaaaatcat
    13261 ataaaaaaca aacggtcata taaaagggtt tccatggatg ctgatacaca ttaatattta
    13321 cttgtaagtt ggaacaacga tatgggggga gcaagcaaat gagtaaaact gtcaatgaag
    13381 taacaaaaga aaagtggtta gtagaaacat ttcctgagtg gggcacatac ttgaatgaag
    13441 aaatcgaaac agaagtagtg gatcctggaa cttttgctat gtggtggctg ggctgtacgg
    13501 gaatttggct gaaaagtcat gaaggaacga atattttatg tgatctatgg tgtgggacgg
    13561 gaaaacgtag tcatgggaat ggcatgatga aaaaaggcca tcagatgatg cgtatgagtg
    13621 gcgttcaaaa tatgcagcct aatttacgta ctcagccttt cgtaatcgat ccttttgcga
    13681 taaaaaatgt agacgcttta atcgttacac atatccattc cgatcatcta gatatccata
    13741 cagccgcagc agttcatcaa aattgtcctg aagcaacatt cattgggcca aaagaagtgg
    13801 ttcgcacgtg gcaaaaatgg ggaattcctg aagaaaaaac gattacagta aagccaggtg
    13861 atgcagtcaa aatcaaagac atcaatgtag tagctttaga agcgtttgat cggacagcgt
    13921 tggtcacttg tgaagatcca gaagaggtat taaaaggaaa aatgcctcag gagatggatc
    13981 aaattgcagt aaactattta ttcgaaacat caggagggaa tctttatcat gcaggagatt
    14041 cacattactc caatttattt gccaaacatg gtaatgaaca caaaatcgat gtctgtttag
    14101 gggcctatgg tgaaaaccca cgagggataa cagacaaagt tacttctgtt gatatgctgc
    14161 gcatggcgga gtcattgaat gcaaaagtag tgattcctgt ccactacgat atttggtcta
    14221 attttatggc tgattcaaaa gagatcactg aaatttggaa attcaaaaag gatcgcctga
    14281 agtatggatt taaaccttat atctggcaag taggcgggaa attcatctat ccgacaaaca
    14341 aagatgatct tgagtttaat ttttatcgag gatttgaaga tgtcttctcg attgaaaatg
    14401 atacaccgtt tccgtcgttt ttataagaaa gaaggggagt ttcttgctga aatacttttt
    14461 tgaccatcaa ttgattcatt acccagataa agaaatcacg gattggcgtg aagctatcgc
    14521 cgaaagctgt cttgtattga tcgataagga aattattgat gaaacgtatg tggaggagat
    14581 catccattgt gtagaaaaat acggtcctta tattgtgatc gcacctcaag tagcaatgcc
    14641 gcattcttca gaaaaaagtg atggtgtttt tggaacagct atttcattta ccaagttgaa
    14701 acagccaatc cgttttgaaa gtgaagggga ggatgaggag aaaacggcta gtttgttttt
    14761 tacacttgca gcaaaagatc cagaagaaca tctagaaaat atccaaaaat tatccgaatt
    14821 attaatgaca gatggattgg ttgagcgtct catctctacg aactccatcg atgattacca
    14881 agttgtgatg gcagaatata attaattgat agaggagaaa aaagatgggg gaatttttgt
    14941 taagcatttg gacgtatttt gcaacaaata tcttgacgca gccagcatac ctgattggtt
    15001 ttatcgtgtt attaggctat attttgctga aacgcccgct tcatgaatgc atcgctggat
    15061 tcttaaaggc aacggtcggt tactttattt tgactgttgg ctctggtggt ttggtcaata
    15121 attttcggcc gattttggtt ggactaaagg aacggttcaa tttggatgcc atggttacag
    15181 atccttattt tggacaaaat gctgtggatg ctggattaat ggagacattt ggccgtacct
    15241 ttggagatgt gatgatttta ttactgattg catttgtttt aaatatctta ttagtccgtt
    15301 ttcagaaata tacgaaactg cgttccgttt tcactaccgg aaacgttcag gttcaacaag
    15361 cagctaccgc tttttggatt ttactgtttt gctttcctga tctaggtagg atacaagtat
    15421 tgatttttat gggactgatt ttaggttgtt attgggcagt agcttctaac ttaacagtag
    15481 gaatcacgca ggaattgaca gaaggtgccg gatttgcagt ggcacatcag caaatgttcg
    15541 gaatctttat atttgcaaaa ttagctgagt ggatgaaaaa gcgggatgaa aagaaaaata
    15601 gatcaatcaa gcaagacaaa aaaatcgaag atatcaaatt accaggattc ttgtcgattt
    15661 tcaatgagaa tatggttgct acttcgttac tcatgctatt tttctttggg atcattctga
    15721 ttgtactagg caaagattat ttgattcaag cgcaattcat gcaagaagga cagagtttct
    15781 tattctacat tatgacgact tctttaaatt ttgcggtata tctggcgatc ttgcaattag
    15841 gtgttcggac attcgtcgat gaactaactc aatctttcca aggaatctca aacacaattt
    15901 taccaggagc tgttccagga attgacgtag ctgctacttt tggctttggt tcgccaaatg
    15961 cggtaacgat tgggttcttg tttggtgctt tgggacagtt tttgatgatt ggtttactga
    16021 ttttattgaa atcaccaacg atcgtcatag ccggtttcat tccgttgttc tttgataatg
    16081 ccgttatagc agtttatgcc aataaccgag gtggattcaa agccgcttgc ctgttcccgt
    16141 ttctttcagg aatcatacaa gtaggcggtt cagcattatt cgctacatgg attgggatgt
    16201 caacatatgg tggttatatc gggatgttcg actgggcaac agcttggcca ttgtttacag
    16261 taatcatgaa agtcctaggt tatgctggaa ttgccgtagt tgtcattggt ttattggcta
    16321 ttccgcagtt acaatatcgg aaaaatcctg agggttattt tttgattgta gaagactatg
    16381 acacatatgc agaaaagcag agagtataaa agaaaatctg attagacaac actcataatg
    16441 gagggattaa gatgagaatt ttagtatcgt gtgcaaatgg atcaggaaca agcttgatga
    16501 tgatgagaag tgtggaaaaa gcaatgaaag aactaaacgt accaattacc aaaatccatc
    16561 attgtgccat ttcagaggga aaaagttcag ctggccaata cgatgtagtt tttacgccag
    16621 tcaatttttt gaatatgttt actcaggcag agaaaaaaga agttacagtt atcggtatca
    16681 aaaatgtgat gtcagccaaa gaaatcagtg aaaaatttgc tgaaacaaag tggtaccaaa
    16741 aaaacaagta aaggaaggaa ctaagatgag caggccgaat ttgcaaattg cgttagatca
    16801 caatgactta gaacatgcat taggagatgt tatgaaagtt ggtgatgtag tagatattat
    16861 tgaagtgggc acaattcttt gcttacagga aggacaaaaa gcgattcgct gtattcgcag
    16921 tatgttccca gataaaaaac tagtcgctga tacgaaatgt gcagacgctg gaggaacagt
    16981 ggcgagtaat gttgcaaaag caggagcaga ctggatgaca gtcatttgtt gtgcaacgat
    17041 tccaactatg gaggcagcac aaaaagaaat aggtgaattg caagtagaac tctacggcaa
    17101 ttggactttt gaacaagcca tggattggca taacatcggt atccggcagg taatctacca
    17161 tcaaagccgt gatgcgctgt tatctggtga aacttggggt gaaaaagatt tatcgaagat
    17221 caaaaaactg attgaactag gctttaatgt ttctgtaact ggtggattaa atccacacac
    17281 attacactta tttgaaggga tcgatgtgta tacctttatc actggtcgtg gtattacagc
    17341 agcaaatgat ccgatgaagg ccgcacaaaa cttcaaagat gagatcattc gtatctgggg
    17401 gtaaggaaat ggctcaaatt gggatttatg aaaaagcatt acccaaagat atttcatgga
    17461 aagaacgttt ttcccttgta aaagaaatgg acttcgattt tatcgagatg tcgattgatg
    17521 agacggatga gcggttagca cgattagatt ggtctgaaga aaagatagct gagctgagag
    17581 aagagatgtt cagctccggt gtacgtatcc attcgatttg tttaagtgcg catcggcgat
    17641 ttccgtttgg ttctgctgat ccagaaaaga aaaaagcagc gaaacaacta atgaaaaaag
    17701 caatccattt ggcgcataat ctaagcgtca aagtaatcca aatagctgga tacgatgttt
    17761 attatgaaga gaaatcaatg aattccagag aagactttat cgaaggaata aaagaaagcg
    17821 taaaggaagc ttctaaatat ggcatcattc tttccgtgga aatcatggat gatccattta
    17881 tgaactccat ttcaaaattt ttagaaatca aagaacagat tcattcccct tttctacaag
    17941 tatatccaga cctaggcaat ttgtccgcat ggccggaaaa taatccggct cgagaacttg
    18001 agaaagggat cgattatatc actgctatcc acttaaaaga tacttaccct gtaacaaaag
    18061 aatattcagg ccagtttcgt gatgttcctt ttggtagcgg ttgtgttgat tttcttggat
    18121 tattaagaca tttgaaacgt ctagattatg atggaacatt tctgattgaa atgtggagtg
    18181 aaaaaagcca agactttcga agagaaatcc agcaggcaaa agactactta agttctaaat
    18241 tgaaggaggc tggctatgat gtcttgtgaa gaaaaaattg cagcaatgaa gcaacgtgtc
    18301 cttgaagcaa atctggcatt gccgcgatac ggattagtca aattgacttg gggcaatgtg
    18361 agtgaagtgg accgtgagct aggagtcatc gtcattaagc caagcggtgt cagatatgaa
    18421 tgcatgcaag cagatcaaat ggtggtaaca gatttgtcgg gaaatataat agaagaagat
    18481 agcttaaaac catcttcaga tctccccaca catgttgttt tgtatcaaac ttttgaagat
    18541 ataactgcta ttactcatac tcattccacg cactccgtca tgtgggcgca agcaggacgc
    18601 gatttgccag cttatggcac gactcatgct gatgcttttt atggtaaggt tccttgtaca
    18661 cgccaattaa cgaaagaaga agtaagagaa gcttacgaag ttcatacagg gaatgtgatt
    18721 gtcgagacgt ttaaggaaag aaaattagat ccaaacgaag tccctggagt acttgtctat
    18781 ggacatggac cgttcacatg gggggattca cctatgaaag cagtagaaaa cagtttgatc
    18841 ttagatgaaa tttgtctgat ggccaaagaa aacgagctga tcaaccccaa tatatgtgaa
    18901 atcccgcaat atttactaga taaacattat tttcgcaaac atggaaagta tgcatactac
    18961 gggcaataga gatgctaggg taagggtaga aaattaaaag ataacacttg atagagagaa
    19021 acagaggttg tgaagaaaat ttatcacaac ctttttattt atcaaaaagg atgcattcta
    19081 aaaggaaaga gagattttaa ggaatcgaga gaatctttac aggagagtta tatgtgatag
    19141 attaaatagt caaagaactg tattattaga gggagaattg tataagaaag gaagaaaaaa
    19201 atgaatattg attcccttat gatcgatgag atttctgaat tatataagag cgttggttgg
    19261 acgaattaca caaaagacac tgcaaggtta gctagagcat ttgaacaatc tgaatctctg
    19321 ataaagcgta atggggaagg gaagattatc ggaatcgttc gttggatcac tgattttgcg
    19381 acgatcgcat ttattcaaga tatcctcatt catccgaggt atcagcgcca aggaataggc
    19441 aaagtgcttt tgaatgaagc tttggagaag atcactagtt atggaccagt ccaaatcgaa
    19501 ttattgacag atgatactga gaaaacaaaa aaattttatg aatcagtagg atttgttcaa
    19561 gtaaaggaaa tgggtggtat ttcttatgtc atagatacta gaagaaaaaa ggtgcttttt
    19621 ggtaatgaca aataacatat aataacgtac aaaagaaaaa attctagctt agttctttag
    19681 aaaaacaaga ggatagactt agtatcactc aatctatcct ccaatgctca gctattttat
    19741 ttttttactc acctctttat caaatacaat tttttgcaaa ttcgaactaa tataaaaaat
    19801 gaacacatga ttttttttta aagcaaatgc tatgcgataa ttttttttat taattttgac
    19861 tttcatctcg tatattcctt ttgccgaacg agtacgcact ggctttatac gaaaaaaatt
    19921 atgctccaaa tactctgtca ctttgtggga aattgcttct ttatacatga aatgttcttc
    19981 ttgtggaaat tgcttaagta gttcactgtc aaattcaaca gtataatcca tgttttattt
    20041 cctttctata ctgatacatt ataaaaataa acaattttat aagtctctat atttcatgat
    20101 gaatgacaag tatatttgat tcatcttgat atagctctac gagatctcca attccaggat
    20161 acatattgaa ataatcatat ggtatacaaa catttatttt ttttcaattg tcaacactgc
    20221 gtcttcttct tctaattcta taatcttagc aatttgtacg tcgcttttca tgtgtgatct
    20281 tcctttctat acattggatt tacttttcga tgatatctac aacagctttg ccacaagtca
    20341 gttctttttc tagctcgttc tttattttta tggcacatgg tttggaaaaa ggagcagctt
    20401 ctttccatga accaagtaaa ggatattcgt tactgatacc tttcacatat tgtttgtttt
    20461 tgacgccttt tgtttttact tctacataat acatttgatc ctcttctttc ttgctgtttt
    20521 tagttaatat tcaaatatat gtaagtgaaa atgattatgt atctatatct ttatgataaa
    20581 taaaaagaat caatttgaaa gtttttttca ctcgatataa ctaatttgaa taatatatat
    20641 aataaaaggc tattgttctt aaaatataaa tagtatataa agagattgaa ggtaatgctc
    20701 gaatgaacat taccttcaat cttaatgatg cttataacta acgtaataaa aacctgaaac
    20761 aaaaatagct ccgccgatga tatttccaat ataaacgggg ataaaattcg agagaaattc
    20821 taaccaagtc gcttgacctt caaatatggc agcaggtatc acaaaacagt tggccacact
    20881 atgctggaaa ccgattgcca caaaaatcat gactggaaac caaatcgtta gtactttgcc
    20941 ggccgcatct tttgctccat atgataacca taacgctaaa ccgacaaacc aattacaacc
    21001 tattccggag cctaatgctt gccaccaaga aacagcgatt ttatgatcag caatatgaat
    21061 cacttggtcg agatagacac ctgaatgagt taaaccaaca aagtgtccaa agaaataggc
    21121 aacgaaaatt gcaccaataa tatttgcaaa agtaatcact gaccaattct taaccagctg
    21181 tgagaatgtg acttttttat ccataaaggc aatcgccaca gccatcatat ttccggtgat
    21241 caattcacca ccgccaagaa ggatgaccag caggccgata ggaaaaaccg aggcaccaac
    21301 taaactagtc aagctagcca tagattctgg gatagaagca gagactcgta cgtatgccaa
    21361 ataacctaga gaaatcatgg ctcctccgat aaaacctaaa atcagtttag ctaagatagg
    21421 tttatgtatt ttttttgttc caagatgaat actgagttcc ataatttctt ctggtgtgtg
    21481 cataatactt cgattcctac tttcttaatg aattttcatg tgataaaata tagtgaaaaa
    21541 aatcacattt tctttgttga ttatatcatc ttattattta tatgtgcata ttattgtaaa
    21601 attttctatt taatcacatt tgattctaaa aaagaaacaa aaataaaagt catgtatatg
    21661 gtggtcaaaa agtaaataat atcagttatc aaatttcctg taaattttct tgaaactaca
    21721 gcatattatt acttcaaaac aatctacatt ttttataaaa aaggaaatga ataactgaaa
    21781 aaattattat aggagagaaa aaatgtcaaa atctaaaaaa aatatcacca taattggttt
    21841 aggcttaacc gtatatttat ttacagaatt tgtttataga catgtgaatt tatttgcaga
    21901 acctttattt gtattatacg aatcaaattc ctcaatcgtc agtgaacttg ctaatttaat
    21961 gatagcattg ctgtttactc ccgcgttgag agtcataact attttggtct gtttagtgct
    22021 attgtttttt gttaataaaa agaaataacg tagtatttca aaagacaaag aagtgggatg
    22081 atgattgcta tagtatgtta tacgtggtgc taggtaagtg agaataaaca aaaaaggaaa
    22141 cacgcaataa agtttatttc aaaactttat tgcgtgtttc ttttttagat tttttatatc
    22201 tgttgcttta gtagttacca atagttttcg cttaatcaat caaaacgatt ttttgtttat
    22261 tgtattcttt acgaaccttt tcaggaattt cttctgaaat aagataggta aggtcttcaa
    22321 ttggaccgac gatatgatta ctgatggtgc cgaatttatc attagttatc atcccaagta
    22381 cttcagtaga aatacgtatc atctcacgtt taatgtcgga ttcttgcata gttggcacgc
    22441 tcgttccaac atctagatct atgttataaa tacccataat ataaaggtcg gctcgaatgt
    22501 tttgtagttg cttataagct tgtaccccaa tattgatcat agattgttta taaaaagtac
    22561 cgccaatatt gataatttcc aaattaggat gctgtgctaa tgctatggca atcggcgggc
    22621 tattggtaat gattgttgca cgaaaatctt gtgggatttc ttttgctaaa gccaagttag
    22681 ttgtacttcc atcaatgatg atgacagatt cttcttttaa aaaagggagg gctttatgag
    22741 ctaatgcagt tttttgttcg ctagctacag tttctcggta gttaaaattg gtaattggcg
    22801 gaccaacacg taaagcgccg ctgtgtactc tttttaagag accttggcta tccaaatctt
    22861 tcaaatctcg tcgaatcgtg tcttcggata cattgaaacg ttgacttaaa tcactagcga
    22921 taactttttg ttctgcgttt aataaatcta gaattttttg atgacgttct aatttcaaca
    22981 tgttgcgtgc tccttcttat ttattcttgt ttatcatgtc atttatgcgt ttttatgtca
    23041 ataatttccg tttttaatac actaaaaagg cataaacaag caaaaacaaa atatttttat
    23101 gcagttttat gttgactagt atttgttaag cggttacaat gagggggtaa ttaaaggagg
    23161 gaatgtatgg agaaaaaaat tattttgtcg ccttcactta tgtgtgggga tctagcaaat
    23221 ttggaaggaa gcatccaaga actagaaagt attgggatgg attccttgca tattgacgtg
    23281 attgacggtt cttttagtcc cagtatgcct ttagggatcg aaacaatcaa aagaattaga
    23341 gaaatcactt caatgaattt tgatgtacac atcatggcta aggataacga taacgaattt
    23401 tttattggag aaatgttgaa aattggcgta gagagcatta cttttcatta tgaaacaagc
    23461 ctccatattg atcgatatat ccagctcatc aagaattctg gaacaaaagt agggatagct
    23521 ttgaatccag caactccgtt aaatgtatta caatatattt tacccgagat tgataggatt
    23581 tgtttgatgc tgattaatcc aggttttgca acaaacaagt cagaaaaaca agtttcttac
    23641 gcgctaaaaa aaattacaga tctttgccag ttagtaaatg agaaagagtt agcagtagat
    23701 atccaagtgg atggacgggt atcgttagaa acgatcccgg gattattaga tgcaggcgca
    23761 acaaatctgg tattaggaag tacaagtttg tttcttaaag gaaatacatt agcagaaaat
    23821 caaaaactac tttatcaagc gatgaagcaa tcagttagga aaaatcaata gatgtagtgg
    23881 tcctgaataa tagaaatgga ggggaaatag ttgagttata aggcggcgaa acaaaatatt
    23941 gtaagagaaa ttactgaaac attagaccgt atttcttcaa aagatgtgga acaattgata
    24001 aagaaaattg aaaaagcgga acgagttttt ttcgtggggg ttggcagagt actgttagcg
    24061 ctagaaggaa tggcaaaacg cttagggcat ctaggaattc agacagtagt cgtaggacaa
    24121 atcactgaac cggcaattac agataaagat ttattgattg ttggttctgg tagtggggaa
    24181 agtgctttcc cactaactat tgcaaaaaaa gcaaaggaat ttgggtccca agttgcccat
    24241 ataggatcaa acccagacag cacaatgaaa gaatattcag atctttttat tcgtataccc
    24301 gtacaaacaa aattagcgtt accagaggaa atttcttcta tacagccaat gactagcctg
    24361 tttgaacaaa gtgttctttt gttaggagat agtattgctt tagtgatgat agaagaaaaa
    24421 gcaattgata tgtcaaagtt gtggcaatac catgctaact tagagtaggt gaaaaatgaa
    24481 agcggtacat tttggagcag ggaacatcgg cagagggctt attggacaaa ttctacatca
    24541 gaatggattc gatctatgtt ttattgatac gaatcctgaa ctgatccatc aattaaatca
    24601 agataagggt tatactatcg aaattattga tgaaatgaac aggagtgatt tcattgatca
    24661 tgttgtggca ctgaatagtt tatccgagct agaagaggtg attacagcaa caaaaaatgc
    24721 agatatctta acaacatctg ttggcgcaat aaatttagta aaaattgcac cgatcattgc
    24781 gcaagcctta agtaagcgat ttgaacaaaa gcatagcatc aatatcgtag ctaatgaaaa
    24841 tgtgataaat gcaagtgatg tgttgaaaaa agaaatttat tctttgctgt cagaaaaaga
    24901 acaagagaat tttgatgaat atgcatattt tgtgaatacg gcaatcgatc gacaatcttt
    24961 aggaaaagtt cttggaggaa aaatgatctc tgttgtcgaa ccttattatg aatggataat
    25021 ggatcgacag cagttagatc caactacatc ttttgatatg aaaaatgtaa atttggttga
    25081 tgatatggag ccttacattg agcgaaagct ttatatcgtt aatgctgctc atgcggcagt
    25141 agcttattta ggcgcactga aaggatataa gacgattcaa gaagcaatcc aaaatatgga
    25201 gattttcaat ctagtcaagc aatttttaat ggagaatata gagtactttg tacaaaaata
    25261 tcatttttct agagaagaat taacatcttt tgtggaaaaa acattaaacc gtcatgggaa
    25321 tcagaaactc tccgatgaaa ttactcgtgt aggaagttcc cctattcgaa aattaggccc
    25381 taatgatcgt ttaattgctc ccatagtaaa actagattca tatcatttac cttacgatgc
    25441 aggaataaaa gtaattgctg cgggatatca ttatcggaat cttgctgatc cagaagctga
    25501 acaactacgt cgaatgattg taaatgatgg gttgaaagca acgattaaaa agatttctcg
    25561 tttggaaggt aagctgctga atgaagttgt cgctgcttat gagtcccaga tttagaggag
    25621 gagaatatgc taaaagaaca attgtcagga aatacaatgt ttatggatgc gatcgattca
    25681 tggcaagagg caatccgagt aagtgcgcgt cctttgatag gaaagggaat aatagaggaa
    25741 agctatgtac aagcgatgat acaaaatgtg ttggataacg gaaattatat tatattactg
    25801 ccactagtag caatgcctca tgcgcgtcca gaatttggga gcaaaggggt cgggatgagc
    25861 tttttatgtt tagataagcc agtcatgttc ccaagtgaag aaccagtaaa attcttcttt
    25921 accttttctt ctgattcgcc aaagggacat ttagacttaa tggccaatct tggagaattg
    25981 ctgagtgatg aaaaaatgta tcaaaaatta ttcgatgtga agacagaaaa agcattgtta
    26041 gatttgataa agaagtaaag gagagaagaa aatggaggta gcaaacaaaa aaaaacgagt
    26101 ctccatgcga gctaaagttc aagcgattgg cggtttctta acaaatatgg tattgccaaa
    26161 tataggcgca tttattgcat ggggaattgt tactgcatta ttcattccaa ctgggtggtt
    26221 cccaaatgaa tctctgaatg aactcgtaag tccgacagtc agctatctat tgccgttact
    26281 acttgcctat actggtggtc ggatggttgg tggtacacgt ggagctgttt taggtacaat
    26341 cggaacaata ggtttgatta ttggtgctga cataccaatg ttcatgggag caatgattat
    26401 ggggccactt ggtgggtgga tgatgaaaaa aacagatgat tttttagatg ggaaagttcc
    26461 tgctggtttt gaaatggtcg tcaataattt ttctatagga attattggtt tcatactgat
    26521 gtgcctttct tatctggtag ttggaccaat aatccaatca gctaatcaat ttgtaacgag
    26581 tgcaattgaa gcattagttt caactggttt tttaccgata ctgtccttaa tcaacgaacc
    26641 ggcaaaagtc ttatttttaa ataatgttat tgaccaaggt gtttattatc cattaggtat
    26701 gcaacaaaca ttagaggcag gcagatcaat ttatttcatg gtagcatcaa atcctggccc
    26761 tggcttagga ctattgttag cttattcttt atttggtaaa aaggcagcaa aacagacagc
    26821 accaggtgca atcatcatcc attttttcgg cggaatacat gagatttatt ttccatatgt
    26881 attaatgaaa ccactcacta tattatctat gattgctggt ggaatgacag gaatcatcac
    26941 ttttgaatta tttgatgcgg gcctggtagc aggtccaagt ccaggttcta ttttttctta
    27001 tttagctcta acgcctcggg gaaatttttt gggtgtcatg gcgggagtgg tcacagcaac
    27061 actggtttcc ttttttgtaa catcagtaat tttaaaagca gataaatcaa cagatgaaga
    27121 cagaaatttt gaactatcag ttcaaaaatc gaaaacgatg aaatcagaag gaagaaaatt
    27181 attaaaagaa gaaaatgcta gagaaatatg taccgagaaa aaagagatga ataaaatttc
    27241 ctttgcttgt gatgcaggaa tgggaagcag cgcaatgggc gcaacaatat tcaagaaaaa
    27301 attgcaaaaa gcaggtatta ctgatgttga gataaaaaat tatcgaattg aagaggtacc
    27361 agaagatagt gatttggtga tcgtacatca agatttggag gaacggacta gaaaagcaca
    27421 tcctaacatg aaaattgtga cattaaagaa ttatttgcaa gatccagtaa tcaatggatt
    27481 agcagaagaa atcattggat taaaaacaga agactaattt atgggaattt ttgattaacc
    27541 tttattaaaa ttattttgcc taatataaaa aggttgtgac atggcttgtg tcgcaacctt
    27601 tttttgtcgc acaaataatt aatcggatat tttatgttca tattttttgt gatcaacgag
    27661 aactgatggg gcaaagatac attttagata cttttaactg ttaatttaca aaacaaggtg
    27721 aaacgaatag aaaaatgaaa aaatcgatac ggaagaatat gtttgattaa aacatgcatg
    27781 aagagaagga ggttgatgat acatgaaaaa aatatattca aaggaaatcg attgttttag
    27841 aggcattgct gttttagcag tgatatttta tcatttgcca aatagtttgc tgccaggcgg
    27901 attgcaagga gtaacgatct tttttgtggt ttctggtttt ttaatggcta aaaatacgat
    27961 aagagatgaa aaaaacagac aattcagttt tttacatttt tactataagc gtatcaaacg
    28021 tatttatcca tttttactgt tttctttggt cgtattcatt ttcatactag ggattagcaa
    28081 cattcgattg ataggaaaca ttcgtagtga gctacccagt ttgatttttg gctataacaa
    28141 ttggtggcag ctgaatcaag gagtatctta ttttgactct tactttaatg cttctttatt
    28201 taaacattat tggtcgcttt cagttgaact acaattctat ttgatatggc catttttgtt
    28261 tattgtcatt aagcgtatga gaagaaaaca agtgttttac ttaatctata cattgatttt
    28321 tgtttctatt ctttttagtt tgtttttacc ttcaactaag gcatattatc atacgatagc
    28381 taaacttttt ccatttttat taggagtttg ggggtatttt aatcgaataa ctattggccg
    28441 tttctttgaa caaaacactt ttagtaaaat ctggctttta ttactagcta gtctttgtct
    28501 gattctgttc ccgatttttc cttatacact aaatgaacta ctgatcagta tttgttttgc
    28561 tctattgtta gccagtgtcg atgatatgaa cattgcaaaa aagaccaaaa tcgctagtac
    28621 aaaactttct tttgtaggaa aaatcagtta tgaactttat ttggtgcatt tcccagtatt
    28681 gattgctctg acaaatctat tcaaacatca ccattggaaa tatttggata tcgcaggtct
    28741 attcactgtg tttttatgta cattactcat gattacttgc tttagaaaag gagtgcaaaa
    28801 gatgagatca cccaaaattt ggacagctat ggcactaatg ataatcggag tttctgtact
    28861 ggtattacgt gctcctgcca gtcgactgac cgctgaccaa aatcagttgc aaagtttatt
    28921 aaaagaaaac tctagtaaag caaatgcagg agaaaatctg ttgtcacaag agaagaaaat
    28981 attatttatc ggtgattctg ttatgctggg ggcgtatcag gaactaaagg agacatttaa
    29041 aaaagaagca ttggtagatg caaaagaatc aagacaaatc actgcgttac cagaaatctt
    29101 aaaggagcat aaagatttag tttcttacca acaaatagtg atcgggttag gaaccaatgg
    29161 tgtgataaca gatgaagcta tagaacaaac aatgtctttg ctgaaagata aaaaagtata
    29221 ctgggtaaat ataaaagcac caactggctg gcaagatacg ataaatgcca cattagctac
    29281 attgccaaat cagtattcta atataacgat gatcgattgg tatagtgaga gcaaaaatca
    29341 tcctgaattt ttttatgatg atgaaaccca tttgaatgaa agtggacgta cagcttatgc
    29401 aaagtatatt gcttcagtta ttcaataagg tagtgattac gtgtgttaac cttacttttt
    29461 cctaataggt gaatcaattt aaataaaaaa tacttcatat gataaacggt gtttaagagg
    29521 aggagctttt taatattcgt ggtaaaaaag agatgggcga ggtcgttaac tgagagcttc
    29581 ttggaaagaa atcgctttgg atttatcctc tttgttatac agaacatgag cgagacgaca
    29641 atactaggat gtatgttctg atcgaagttt tatggttaca agcagcaatc agcttagata
    29701 aaattaagga tcgtaggaac caagtaaaga aggctgttag taaagaaaca aacgatcaag
    29761 tatgttttac tcttaagaag atgcagtgaa taaataatag taatataatg ctagaaggga
    29821 ctgtgacaaa agacgtgtca cagccttttt tgttatttta attatcgtcc agtctttttt
    29881 tataaatgat tgcttaagca ttaaatatta aaaaatatag agttcaaaat tactgcacaa
    29941 ttagatgaaa aatttgaaca acaaaaagtg tatttttata ctataatagc ttttgaattt
    30001 agttactcta ttcaaaagtt atgctatgga caagaaaaag aataaataga ggtgagaaaa
    30061 tgaatagttt caagaaaaaa tttgtgagta gatttttaaa tatgaaaaat ttttttgaaa
    30121 aaaagggaga ttatgatgca tataattatg tattaaatct agaaaagcaa acatattata
    30181 cactacgtaa aaacgatgat aatgactttt ggactatgtt acctaaaatg ctttcgattg
    30241 actctaagct ttccctttta gaggaattta ttaatttaga cattgaagaa ttttgcgggg
    30301 gaaaagagtt aattaatatg gtagagagtg attatcatac ctattataaa gaaagttgtg
    30361 gatacaaagt ggatgagcaa tgtccacaat caattatttt ttacattgag taatatgaac
    30421 tattaagcag gaaagcaact agaagctact gatttagtat ttacaaatat aaactatatt
    30481 gctaacaatt attttctaga aggaataaaa gaactaagaa tcaagacgtt atcttgattc
    30541 ttagttcttt taacatggaa aagatggata atgcactgtt aattcatgat gcatcatcag
    30601 aaaagttgga aggagaagat agaaatcatt aaatgatttc tacagatggt aaatgaaaaa
    30661 acaaaatatt agcaaaaatt tgcctaaata gatagtaaca ctttctaaat taaatacaag
    30721 cgcattcata aaatgtttat acaaatatct atgtgataaa aattggatat gttcacaata
    30781 aataggaatt aaaataacga atttacgttt gtttttattt accaatcaaa ttatcttaat
    30841 gcaggaataa aaaattaaat tacatattgt taatcattta catctccatt aataactcaa
    30901 aatgaaaaga tgtttttatt tttattctat atttcagaaa aaaattaaac tagattataa
    30961 taattcttca tgtaaaaata aaaacaatta cagctatgat gtttaagata aaacaattat
    31021 gaaatcgata tccgtttata tacttatcat aagctagaag caaataacta gcctatgtat
    31081 gtaagtgaga ttatatttat taaaaggctt cttttgttcg atcagttata gtcgaacgag
    31141 agaagtttat tctttgatta aaataaacaa aagtaactta ttgaggtgaa atgatgcaaa
    31201 cttttttaac taaaacatct ttcaaaaaag tagttttatt agattatttg ttagaaaaag
    31261 acaattggtg tgcaatggaa gaacttagaa atttacttaa tgttacggag aagtcagtct
    31321 tacactatat agaagaacta gaggatttat ttaagcaata taatggtaat atccttctga
    31381 aaaatgaaga taataaacga tttttcataa aaaaagagaa agattttcct atttataata
    31441 tttatcttca tttttataaa gcttcttata attatcattt gattgatttt atgtataaat
    31501 atcctagaag tgttctaaaa gattttgcta aagagcaatt tactagtgta tctactgttt
    31561 tcagatatgc gaagctctta attccatatt ttaggcgtta tcatataaca tttcatccat
    31621 ttcagttaga attgaatgca tcagaggcaa acattcgtag ctttttttat tatttctatt
    31681 ggaattctac acgtgaaagt agtgataagt ggccatttca tatcgaacaa aaggaaatag
    31741 agaagtatat agttgctttt gaggggattt atgatattac gttaactatt tttcaaaaac
    31801 gtgtattttc tttttggtta gccattaata tagaaagaag ttcatttaga aaagtacgag
    31861 tagataatga atataaatca gttatctcag atgatccgca ttttaatctt ttgaagaagt
    31921 ggtcaaaaca aatcaatctt tcttttaaca gcgatgaact gtgtttcctt tatcgaataa
    31981 tttattcttt tggagtaatt gatggaaatg caatatatga aaatagtcat gcatatgcac
    32041 atcagcgaca aaatacttgt tcttatcgag cagttgagaa tttggagaaa gttttacaaa
    32101 gcatgttccg tttttcttta gatataaagg atccagaact cacattcaat tttattgcat
    32161 ttcatgaaag aagttatcta ttttatggta atccagatct tttttttaat cgttcgtata
    32221 tcgaagaaat gaaagaagaa gaacctcgaa cttatcacat aatggaaaaa ctcaaaaaag
    32281 aattacaagc aaatgcggat ttggatgtat caaagaaatt agaaaactgg gcacaattat
    32341 ttttggatta ttattatgtg ttagattatt atgatttatt tttaacaaat gttaaaccga
    32401 ttaagattt
//
LOCUS       DACGLI010000036        30871 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.037, whole genome shotgun sequence.
ACCESSION   DACGLI010000036 DACGLI010000000
VERSION     DACGLI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.037"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(402..956)
                     /locus_tag="IXT22_001757"
     CDS             complement(402..956)
                     /locus_tag="IXT22_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAQ4863108.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(1082..3011)
                     /locus_tag="IXT22_001758"
                     /pseudo
     CDS             complement(1082..3011)
                     /locus_tag="IXT22_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(3317..4033)
                     /locus_tag="IXT22_001759"
     CDS             complement(3317..4033)
                     /locus_tag="IXT22_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4863109.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(4034..5857)
                     /gene="glpO"
                     /locus_tag="IXT22_001760"
     CDS             complement(4034..5857)
                     /gene="glpO"
                     /locus_tag="IXT22_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAQ4863110.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(5871..7367)
                     /gene="glpK"
                     /locus_tag="IXT22_001761"
     CDS             complement(5871..7367)
                     /gene="glpK"
                     /locus_tag="IXT22_001761"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAQ4863111.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(7503..8963)
                     /locus_tag="IXT22_001762"
     CDS             complement(7503..8963)
                     /locus_tag="IXT22_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4863112.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(8953..10248)
                     /locus_tag="IXT22_001763"
     CDS             complement(8953..10248)
                     /locus_tag="IXT22_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863113.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(10580..11257)
                     /locus_tag="IXT22_001764"
     CDS             complement(10580..11257)
                     /locus_tag="IXT22_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAQ4863114.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(11287..12378)
                     /locus_tag="IXT22_001765"
     CDS             complement(11287..12378)
                     /locus_tag="IXT22_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAQ4863115.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(12479..12913)
                     /locus_tag="IXT22_001766"
     CDS             complement(12479..12913)
                     /locus_tag="IXT22_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4863116.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(13497..14954)
                     /gene="ascB"
                     /locus_tag="IXT22_001767"
     CDS             complement(13497..14954)
                     /gene="ascB"
                     /locus_tag="IXT22_001767"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4863117.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(14951..16846)
                     /locus_tag="IXT22_001768"
     CDS             complement(14951..16846)
                     /locus_tag="IXT22_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4863118.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(16904..18679)
                     /locus_tag="IXT22_001769"
     CDS             complement(16904..18679)
                     /locus_tag="IXT22_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4863119.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(18729..20225)
                     /locus_tag="IXT22_001770"
     CDS             complement(18729..20225)
                     /locus_tag="IXT22_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4863120.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(20419..22041)
                     /locus_tag="IXT22_001771"
     CDS             complement(20419..22041)
                     /locus_tag="IXT22_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4863121.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(22369..23682)
                     /locus_tag="IXT22_001772"
     CDS             complement(22369..23682)
                     /locus_tag="IXT22_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4863122.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(23927..24151)
                     /locus_tag="IXT22_001773"
     CDS             complement(23927..24151)
                     /locus_tag="IXT22_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863123.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(24171..24539)
                     /locus_tag="IXT22_001774"
     CDS             complement(24171..24539)
                     /locus_tag="IXT22_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4863124.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(24735..25445)
                     /locus_tag="IXT22_001775"
     CDS             complement(24735..25445)
                     /locus_tag="IXT22_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863125.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(25463..25960)
                     /locus_tag="IXT22_001776"
     CDS             complement(25463..25960)
                     /locus_tag="IXT22_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863126.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(25997..26449)
                     /locus_tag="IXT22_001777"
     CDS             complement(25997..26449)
                     /locus_tag="IXT22_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4863127.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(26584..27189)
                     /locus_tag="IXT22_001778"
     CDS             complement(26584..27189)
                     /locus_tag="IXT22_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4863128.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(27639..28259)
                     /locus_tag="IXT22_001779"
     CDS             complement(27639..28259)
                     /locus_tag="IXT22_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4863129.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(28261..29130)
                     /locus_tag="IXT22_001780"
     CDS             complement(28261..29130)
                     /locus_tag="IXT22_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAQ4863130.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(29153..29560)
                     /locus_tag="IXT22_001781"
     CDS             complement(29153..29560)
                     /locus_tag="IXT22_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4863131.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(29579..30868)
                     /locus_tag="IXT22_001782"
     CDS             complement(29579..30868)
                     /locus_tag="IXT22_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863132.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT         8763 a         6690 c         5104 g        10314 t
ORIGIN      
        1 ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg
       61 atttctacat ttttgcataa atttggctta ataccgagaa actggctttt gaataccgtt
      121 taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagaaaca aacggaaaaa
      181 tagctgctca tattttgccg ttttttgagc taataccgaa ggtcagctga ttgaacaccg
      241 tttaccaaga ggttgtgagc ctaccattta actccgaatc acaagaaata atttcaaaaa
      301 caacttctcc tgtttttggt tcggttggct tattatcgag aagtagctac tgggagtcta
      361 tttatcaaaa aaaggaatgc gacataggtc acaccccttt tttattttct ttgaaacatc
      421 tttcggtact cgacagcata caagacaaaa gattgtaaaa gaccgtaagt gatgacggca
      481 aaaatgactc tcacccacag cgttggtaat tctgggaaaa gcagcaaaag gatcatgcca
      541 acatagatga cagcagtcgc tactttgcca taccacttcg ctccacttaa tttgatattt
      601 ttagatagcc cgattaatcc agctacaaac ataaagcctt cttttatcaa gaatagacca
      661 aacaacagcc aaagccacgg tcgataccat gccatagaca aaatcagaaa aagttgtgtc
      721 aatttatctg caaacggatc aagcaccttc cctaagtctg ttacctgatt atatctccga
      781 gcaatgaccc cgtctagata atcagacaaa cctgagacaa caatgaccgc tcctgctata
      841 taaaatgact gtctcagcac aaaataaaga taaatcggca gcaaaaaaat acggaatatc
      901 gataaaagat tcggaatcgt ttgtatttct ttacgccagt ctgtgcttaa tttcatttta
      961 tcgccctacc tcctcagcac tcttttcttt ttattttagc ttacacgggg aataaaacca
     1021 atgatttcac tgtttttatt tttctttaca gacactgata ttatgagcta atttgagata
     1081 atcacttgct gttttcatcg tttactcttc tttcttcctg tcgtttgcgc atttctttta
     1141 ctagtacttt atgagctttt tttgatcctc gctctaggtc acgctgccgt ttacgtgttt
     1201 tataatcgat aaacagactg tctaaatcgt aacctgtcgg gtacagatct tctgctgaac
     1261 gcaccagacg aacacgctga cgaggcacgt ggattatttt tttgtctaaa tatacatcaa
     1321 tcgtatcttc acctatatct tcataaacta acgcttcttt ttggtattca ttgacaaata
     1381 tccgatcacc ttttgcaaag agctgacgtt cttttttatt ctccttccta tttgtaactg
     1441 ctgtcttagg aagaaattct tttttctgtg tccgataggc tttttccgcc aagtaacgct
     1501 ctgcttgatg gatcaatttc atcgacatat ccattttatg agcaatccac aaagcttggc
     1561 tttctcctgt ttcttccaac ccgcaactga tatttaggac gaagtgcttc ccgatcgaaa
     1621 gccatagcag ccggcacaaa atcttcatga tctccggcga atttcttgat ttctccataa
     1681 tgggtcgtgg caatgatcaa tgccccttgc tcatacatag attccatgat tgcgatcgct
     1741 agtgcagccc cttcatttgg ctctgttcca ctgccaatct catctaaaag taccaacgta
     1801 ttccttttta tctttttcaa aatagcagcg atgttttgca tatgaccaga aaatgtactc
     1861 aacgcatttt ctaaattttg gtggtcaccg acatcgacga aaatctcatc aaagacagca
     1921 agctctgtcc cttcttttgc cggaacttgc ataccgaaca tcgccatcaa agtcaataaa
     1981 ccgactgtct tcaacacgac tgttttgcct ccggcatttg ctccggtgat aatcaagcct
     2041 cgatagtctt taccgatttc aacatccaat ggtaccgcat gctcaggtaa aaatggatgt
     2101 ctgccttgct tgataatgat atgttccgat ttattgattc taggtgtgct tccattgatt
     2161 tctcggctaa attttgcccg agcaaagatg atatctaaca ccgtgatcgt ttcgatcaat
     2221 aaatcgatca cttcttcgtt ttctgcgata gcaccagtca atgccgccag gacttgatat
     2281 tcttcactga tttcttcagc ttttaacaac tgatagtgtt cattcaattt agaaatcaca
     2341 gttggttcaa taaaaaccgt cgttctttta tttgattcat cgataatcgt tccatctatt
     2401 ttatttttat agctggcttt gataggaatc gtatagtatt cgcctttttg aacaatcatt
     2461 gcttcttgga tcatttcttt gtttttcgga tgacgcaaga atttcagtaa ttttgactgg
     2521 atttcttttt cgattagttg taattgtttg cgtactttac gcaaattacg tgacgcgtcg
     2581 tcactgactt tattattttt tattttctgg tcaatcaact cttctacatt tatcaaatca
     2641 ggaagatgtt tgctataagc aaacaacaag ggtgtctggt attgattctt atcaaaaaac
     2701 tttgtgatca tccgactgct tctaagaaaa tccgcatatt cgatcaaatc ggttggctgc
     2761 agaatcaacc cttttttgac ttgttctgtc agtgcatcga tcctcggcaa ccccataaat
     2821 ggaacatgct gactgctttc taagatcaag cgtgcttctc ttgtttcttc ttgacgatcc
     2881 aagacagttt gtaggtttgt cgagaccgtc atatcgctga ttcgtttttt gctatagttt
     2941 ccaattgctc ttgcttggat ttcctttttg atccgatcaa attgtaattg actaatcatt
     3001 tcgttgtcca tattctctcc ttttcttgaa gagatacctg tcccaaaata aataagggcc
     3061 tagagataaa taaaaggata gaacacagct taaaaaagtc atgtcctatc cttattagaa
     3121 tacaaagata ttgttttcct gacaggtacc gtttcataag cacaccaaat aaactttgtt
     3181 tattggctat tcgacttact gattagatac cagctacact cacaaaacat accccattct
     3241 tctaggtctt atttattttc cacttaacta tagcaagaca cattttggtt gtcaaacttt
     3301 agtatgtttt atagatttac accattaatg aatagacacc taccgcgata attgctccga
     3361 tcattggacc tgcgattggt acccatgaat atgcccaatc tgaagttcct ttattagcta
     3421 ttggcaatac cgcatgtgct aatcgaggac caaagtcccg agcagggttg attgcatatc
     3481 ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa tccacctaca gcgaatacgt
     3541 tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa cccaagaact aatacaaatg
     3601 taccaattaa ttctgtgatc acatttgctg gataattccg tatagcagga cctgttgcaa
     3661 acgttcctaa aatcgcgctt tcatctttcg ttgcattcca atgtggcaaa taagaaagcc
     3721 aaacaagaat ggcccctgca aaagctccta aaacttgcgc aatgatgaaa ggaacgacaa
     3781 gattccaact aattgcccct gtcatcgcca tagctagaga gactgcagga ttcaaatgag
     3841 ctgggcccat gaatccagaa atatagacag ccattgttac agcgagtccc caaccaaatg
     3901 cgatgacaat ccagccagaa gcctgtgctt tacttttgtt taaattcaca gccgcacaca
     3961 caccatctcc aagcaaaact aggatcagtg tcccaataaa ctcccccatg atttgagtca
     4021 tatcactgtt catttatttc tcccccttta gttcccgcag atctgattct gcaatcaatg
     4081 cttctaaacg tttagtctgt tgcgccttct cctcttctgt ccattcaaaa tatccagcaa
     4141 ttgcatcgat cacaggttgc ttgatctcat caagctgatc tcgttcaaac aacagatgat
     4201 ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat ttcttcttct aaaccataac
     4261 gtaaccgagc tgactcagcg agactcaaac caggataagg tgccatttct tttgctaatt
     4321 caaagatacg tcgggcatta gtcccgtaaa aatcagcgat ataagtagca tcttcttcct
     4381 ctaaaccggc tgctactcct tcttttgcta attctgtcac tgtttcttct aatttagttg
     4441 gatcgaagtt tccacctgaa atctgatatt ttttagagtc gatttctttc gtctctattc
     4501 cgtattcttc ttttaataat tggcgtatca atcgcaaagc tccttctgcc atcttacggt
     4561 aatcggtgat tttcccacca gataaagtca gcaaaccatc tggttctctt tctaaagaac
     4621 tacctctgga aatcgtagaa ggtgcttttt catcacggct gttttccaaa tggttcaaca
     4681 cgtcttctac ttcagcacga gaaactttgt tttccttata ttcacttact gtatcgacaa
     4741 ctttattgaa gctcttgtct gaaatcgatc cattatctcc accattgtaa tcagaaccag
     4801 aattaccaat caacagtgga cgaagtcctg cccagcttgc ttcgatatca ttcaatgtga
     4861 tatttgcttc tggatagcga tgattgatca catccaatag ataatctaca tcttcttgtg
     4921 tgactttcgg atccgtaaaa tctccttggt aatccgtatc tgtcgtacca aagtaagtct
     4981 tgttttctct tggaatagca aaaaccatcc gcccatcttg ctttcctgta tcgaagtatg
     5041 tgggttgcgg tacaggcagt tttttcgcat ctacaactaa atggatccct ttagttggac
     5101 gcattttagg agagactgga cgcgtaaaat tcaagtttcg tactttatct acccaaggac
     5161 cactcgtatt gatcactaat tttgctttga tttcgatcac ttcatctgtc agcaggtcac
     5221 gagctttgac gccaacgatt tgatcgccat catataaaaa gccaaccgct ttcattttac
     5281 ttactagata agccccatct tcggcagcct ttttgatatt atcaatcact aaacgggcat
     5341 cattgttgcg gaaatctaga tagacacccg cgccttttag cccttctttt ttcaaaaacg
     5401 gttctctttc caatacttct tctggtgtca gcgtataatt ctcatatttg gttcctgtca
     5461 catttgccag tttgtcataa aggtccattg ctactttgac cgagaacata ttgaaggttg
     5521 ttgctccttc gccctcatag attggcaaaa gcattggatc tggttttggg atgtgtgggg
     5581 caatactttg tacgactgca cgttcaccaa ctgtgtcagc tactacttcc acatcaaatg
     5641 tcttcagata acgaataccg ccatgaacaa gtttggtcga gcgagaggaa gtcccttctg
     5701 caaaatcctg catttcgatc aatcctgttt tgattcctga tgctgctgac tggactgcca
     5761 caccggcacc agtgattccg ccaccgatga tcaacagatc caattcttct tgctgcattt
     5821 tttgaatgct atcttgtctt gtcttgtttg aaaacatatg gatttcctcc ttattcaaat
     5881 gcttgggtag cttttactgc ttttttccaa ccgttgtaaa gtttttctcg gcgctcttcc
     5941 tccatttgaa cttcaaatag cttgccagct tcataaaatt cgcggatctc gtctgtatct
     6001 ttccaataac cgacagctaa tcctgctaaa aatgctgccc ctagcgccgt tgtttccaag
     6061 ttttctgctc gttggatcgg tacattcaag atatctgttt ggaattgcat cagatattca
     6121 ttgtttgctg caccgccatc tactttcaat acaggaatct tgattccagt gtcatcttgc
     6181 atcgtatcga tgatatctct cacttgataa gcaatcgact gtaaagtagc tttaatgata
     6241 tcttcttttg tcgtaccacg tgtcaagcca aacatagccc ctcgtgctgc ctgatcccaa
     6301 taaggagcac ctagcccaac gaatgcagga acaacataaa cctcatcttc gcttgtagag
     6361 cgtttcgctg cgtcttctga atcgctagct ttttgcaaca tttgaagtcc atctctcagc
     6421 cattgaatcg aagaaccagc cacaaaaata cttccttcta aagcatagta aacctttcca
     6481 tttatgccgt aaccaattgt cgtcaataaa ttatttttgg ataattgcgg tttttcaccg
     6541 gtattcatga caataaatga acctgtacca taagtattct tgaccatgcc tggttcgaat
     6601 gccatttgtc cgaataatgc ggcttgctgg tctcctgcca tccctgaaat tggtgcttcg
     6661 cttccataaa aatgataacc ttgcgtataa ccataaactt ctgagttaga agtgactttt
     6721 ggtaacatca ctcgaggaat atttagtaaa tctaaaatct cctgatccca atctagctga
     6781 tggatattga acaacatcgt ccgactggca ttcgagtaat cagtaacatg tgcttgtcca
     6841 tcggtcagtt tccatactaa ccaagaatcg atcgttccaa acatcaattc gcctttttca
     6901 gctcgttctt gcgcgccttc tacatgatca agaatccagc gtatcttcgt tgctgagaaa
     6961 taggcatcga tcactaaccc tgttttttcg tggaaaaatt cttgatagcc ttcatttttt
     7021 aagttatctg caattccagc tgactgtctg gattgccaaa caactgcatg atagattgga
     7081 cgtcctgtat ctttttccca tattactgtt gtttcacgct ggttcgttat gccaatccca
     7141 gcaatctgat ttggtttgat ccctgattcg atgaacgctc cggcaataac tgactgtaca
     7201 gaattccaga tttcatttgc atcatgttcc acccaacttt cttgcgggaa atattgcgtg
     7261 aactcttttt gagaactgcc gatgtgtctt cctttcttgt caaagataat tgctcgtgag
     7321 ctagttgtac cttggtcaat cgccatgata tacgttgatt ctgtcattgt gattccctcc
     7381 attatatgca aacgctttct ttaactactc ttatcatact actgttttaa aaaaagaaac
     7441 tgtcaaaatt ttattctttt tttctttttt tgacagtttt ttattatgaa gctatttttt
     7501 aatcaattct tttctttttt cagcgtctct attcttcttt tcaatcgaat aatgtcgtaa
     7561 ggtgacgcaa attctgacag ataatattca cactgttttt tgtttctctg gcaaaatgtg
     7621 atcaccaaat catattcttt accttcttca taacttccaa tctcaatacc gccgattccc
     7681 ctcagttctc tgatcagata ttgttgaaaa gcaatacgat aaatcggcag actttctaaa
     7741 tcgattccaa tcactactgg ttttgcaata taaaaatcga tcatcaaaag aacattggca
     7801 tactggatca tcaggtaact aagctcacta tcttcagctc ttttcctcgg caattgctgc
     7861 accgctgttt cctgtaattt cgccagtaac tgtgttaagg aatgcccgag cattttctgc
     7921 tgctgttcca aaagccgatc acgctcatag acttcgatct ttccaacaaa gaaaaaccat
     7981 tcattgttga tctgggaaat ttggtagcct actgcctttt cttctttgat tttcaaacga
     8041 cgaggacgat aatgccataa catcgtttcc cgaatgtaag tatctaaaac agcggttggt
     8101 aactttttgc tccgtgtcaa atcatactga taaaatattt cttcgtctac tatcgaaaaa
     8161 gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat tcagttctgc tgctgttcga
     8221 ctaagatgca tcacgatgat tggatcgatt gcttgataaa gccggtccga ctgatagagt
     8281 aatttctttt ctttcaaagt tgcgtacgta cttttttcat tcaatagtct ttttttcgta
     8341 atcccgagcc agcaagcaat ctgtgcttct gctgatgccg taaacgttgt ttctaataca
     8401 cggtccaatc ctagaatgaa cggtcttttt tctggtgtat tttgcaaaaa aagcggtcgc
     8461 tgatcttccg ggatatattg gaatagttca taataaaaat atcgtatctg tagctcttct
     8521 ccgtataatt gaccgttttt gatttgtaat ccaaattcct ctaagagctg gttcaattct
     8581 ttgatctttc gaaaaacaga agactcactg atattaaacg ctgtcgctaa tcgaacgatg
     8641 gatacttgct gatgttctaa taaatagacg agcatcttaa acttcaagct ttcctgcaat
     8701 aaaaacaata gaattttttc caaacttaca tcttcgtcca acacaagcag cgcctgatac
     8761 tcatttcgct gtacttctac ttttttttcc atcattcggc caatcaattc aatatcttcc
     8821 aaatattgat caaacgaggc ttttgacagt tggacatgct ctctcaaacc attgatagag
     8881 gctgttcccc cttgcagaac aaggtttcgc aaaatcagga tctgtaactg ctcttttctt
     8941 tctaataatg cttcaatctt cataggcagt attcgccacc tttgaccaca ccatatctgg
     9001 cacacggtat tctggctgga aaaatagctc atgttcttct aactgttcaa acgtccatcc
     9061 ttcttctact gcaattgtca gttggtcaag aaggtggaac atctcttttt tgctttggag
     9121 ctgtgctcca agaatctttt tttcagaatc aaatagaaat ttgagtttaa ctttgctttg
     9181 atttattgct gtaagcttgt agtctacgta tcctgtttca attttttggg gataaaaaat
     9241 gctctcttct tctgtcaaac ctacgcttcc taagaaatag ccaaaccact gattgccgac
     9301 tggacgatag gttccctgat cctttgtctg tgagccacta attgtcttgc tgacatttcg
     9361 tgctgtacgg acagcgttat ttactagaga aacatacatt ttttcatttg ttggacgaaa
     9421 agttacttgg atcgcatcgc caatcgcata aacgtctttt tgagacgttt gcaagtagtc
     9481 atctacccag atcgttccat catcattcaa tgttaattgt tcttcccaca tctgattgtc
     9541 gggacgagaa tgattagcca gcaaaacaag atcatagttc tcctttcttt tttccgtctc
     9601 tacaatagcg gtttcatttt cggtcaaaga cacaacttgt tcttctaaaa aaagtgaaag
     9661 cccttgattt ttcatttcct ttactaacgg ttctgtcatt tcaggatcta gataacgaaa
     9721 aagaattgac tttcggcttt cgtaaagatg gatttgtttt tttcttgatg ccaacccttc
     9781 agctatttcg attcctgctt gtcctgcacc aataattgca attttctttg cattcatgat
     9841 cttttgctga agagccgtta cgttttgtat ctttttaact gggtgaataa gcgttgattc
     9901 tgcagaaata tttcgaaact tttgatttga accagtcgct agaatcaaac gatcaaaatc
     9961 caattttttt cctcctgcta aaacgacttt tttttctttc aatcctatta ctgtcttttc
    10021 tgtgtaaaca tggattcgat agcggtcagt cagttcttct ttcgtgatcc aagaaagttg
    10081 tttttcactg gtaacctttc cttttaatat caaattgaac ccgctgggaa tccatcctaa
    10141 cttcgattgc ttttcaatca aatatatttc acttgttggc atcaattggc gaagataaat
    10201 agccgcatga atccctgcaa acgacccgcc gacaattaca atgttcatct gcattcctct
    10261 ttcttataag gtgttctact gctaacttct caatcagaaa acacagtatt cataactcgc
    10321 tttcaacctt atgatacata gcgatgcagc agaatcaacc ctctccatca taccgtgttc
    10381 taggtctgct tctcaataat gtactagtgg acctaattga agagtatcat ttctgaagag
    10441 atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg ccttttacgt acctctgtcc
    10501 aaataggaaa cagaaaagaa cgaaaagacg agttttagcg tgtgtaatgt aatagttaga
    10561 atagacacat catttatttt taattcttta atgcttcaac aactgcttcg cctaattgat
    10621 gagcagattg aggattttgc cctgtaagaa gccgcccatc aatttgaacc acttctgaaa
    10681 aagctgctcc agactgatag tttgctcctt tttctttcaa agcatcttct gctaagaatg
    10741 gtacttcatt cgttgtacca tttgcttcct cttcttcatt actgaaccca gtcactgtac
    10801 gtccagctaa aatagatttt ccagactcat ctgtaactgg caacaatcct acaacaccgt
    10861 gacaaacagc tgagaccagc ccttcatttc gatagatttg tgaagcgact ttcccaagat
    10921 ctattgcttc tggaaaatcc cacattgttc cgtggccacc agcataataa accgctgcat
    10981 aatcatttgc atccacatca tcaggacgta aggtatttcc caaggcccga tttctgaaat
    11041 cttcatcttc ataataggcc caatcgattt catccatatt caaaacactt tgcggttcta
    11101 aaggtacata tccgccttta ggactgacaa aatctgcatc gatcccattt tttactaata
    11161 catcataaaa atgagtcagt tcacttaacc acaaacctgt aggacgctcg atcttttcgt
    11221 acttttctac atttgttaat acgatcaata ctttcatttt cccatcctct ttctataaaa
    11281 attgcgttat tgataacgtg ctttcaagaa attatataat gggcttggca aataaagctc
    11341 tttatatgct ttttcaaaag gtttcgttac aaattcatcc tcacggtttt ccaataattt
    11401 ctctgcccag tcaggatcga cgatcatttg ctgtccaatt gctgcaagtt ctgcatattt
    11461 caatacctgc tctacatctt cgcgattgcg gatcccaccg acaccaacta aagggatctt
    11521 tccttgaatc gtgttatgga ccacttcaag aatcgattta tcgttgtatt tatcagaacg
    11581 agctattcga tcatacatat ttaatgaaac atgcagataa tctagttttg actcacgtaa
    11641 tcgttcaaga agccagatcg tgtcttcaaa acggatacct ggtgtttcat attcttctgg
    11701 tgagaaacga taccctacga tgaatggttt tttagcatat tgttcaaccg ctgagaaaac
    11761 cgttgttaat aattcttcaa taaaacgata acgattttcc aagctaccgc cccattgatc
    11821 ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc aaatacgtat ttgctccatg
    11881 caactcgatt ccatcaaatc ctgattcaat cgctctacgt gtggctttgc caaatgcttg
    11941 gattgtttca acgatttctt cttcactcat tgctcgtggt gtttccgcat caggacgttt
    12001 tgctgcaact gcacttgcag atacaggctg ttctccagat aaagttgctc gacttgtcat
    12061 tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct tctccttgga ttgctttcgc
    12121 tagctcactt aatcgaggaa tcatttcatc atgagcgatg ctgagttcac ctggccagcc
    12181 ttttccgata tcttggacat ttgcagcacc agtaataaca gcaccaagac ctttagaacg
    12241 ttgtttataa taagtgatct catcttcggt gatcactcca ttgaaaaagc tgagttgtgt
    12301 cgtcataggc gacagcatca atcggttctt caattgaact cctgaaggta aagtaattga
    12361 ttgatcaaat tgtgacattg tcattcctcc cataattcgc tctgattaac ctatcgagaa
    12421 tcatctatca ttaaaccact cgattagttg tacatgcaac taatttgctt aaaaaatttt
    12481 attttttttg taacttatct gttgcatcat tcattgtctg ggctaattct ttacttgctt
    12541 catttcccaa aactgctttg tatgactgat gaagttcttc ccagctacca tcgacttcct
    12601 tagcaaattg gcgtccttgt tctgtaagat aaactaatga caagcgacct tcgctaactg
    12661 ttttgacgta tcctttatat tctaattttt caacaaaacg agcaatcgtt gatggggcgg
    12721 aatagagcat ttgtgcaata tctttttgtg gtattccatc tttttctttt aatatcaata
    12781 aaataaaacc ataagttggt gccagacctg tccttctaaa cgcttcatca gctaatttat
    12841 tcaacatgcg atctagcttt ttcacgctaa agaaaagaca ttcatctaac gctttttcaa
    12901 ttggcttttc catttcatcc cctccattgg cgtacatatc atagtatgat ttttattttt
    12961 tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag atttgaaaaa aagaagtagc
    13021 catcttcaaa gaatttcggc ttgttttcga caaaactcct tctggaacac cgtgaatcag
    13081 aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa attttgtgaa aatggctttc
    13141 cacatttttg cataaatttg gcttaatacc gaaaaactgg cttttgaaca ccgtttatat
    13201 cagaggttgt gaaaaagccg tcctgcatca agtaataaga acagccaaac aaaaatagtt
    13261 cctcatattt tgtcgttttt tgagctaatg ccgatggtca gctgattgta caccgtttat
    13321 tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag gagcaatttc aaaaaacagc
    13381 ttctcatgtt ttatgactat ggtgacttgt gatcgaggag ttggcaggag aatactgttt
    13441 attcgtaaag aaggggctgt gacaagactt ttgtcacagt cccttatttc cttttattat
    13501 aggatttcgc catttgattg gatgacttgt ctgtaccaat caaatgattt tttctttaac
    13561 cgtttctttg tgccattccc ttcgtcatct tgatcaacat agatatatcc ataacgtttt
    13621 gacatttgtg aagtagaagc gctgacgata tcaatgcagc cccacgacgt ataaccaaat
    13681 aaatctactc catctttgat agcttccttc atctgctcaa tatgctgctt caaatagtca
    13741 atgcggtaat cgtcttgaac ggttccatct tcttctactt tgtctatagc tccgagtccg
    13801 ttttcagcta tgaacagtgg tttttgatac ctatcatata attgattcaa agcaattctc
    13861 aaacccttag gatcaatctg ccagccccat tcacttgatg gaagatacgg atttttaatt
    13921 cctccagtta ttaagtttcc ttggacccct tcccaatttt ctggatgagc actgactgca
    13981 ctagacatgt agtagctaaa agaaacaaaa tcaacagggt aggctgctaa gatttcttca
    14041 tcacctactt ctatttttaa gttgacacct ttttcttcaa acattcgttg cgtatacgct
    14101 ggataatatc ctcttgcttg aacatcacta aagaacaaag aagttctttg ctgctcaatt
    14161 gttttttgaa tatcatccgg atcacaagaa tacggaacaa gaagctgata gctgatcata
    14221 caaccgactt gtgaaccttt gataatttca tgacaagctt ttgtagctaa agcacttgct
    14281 ataaactgat ggtgtgcacc ttggtatttc gcttgttcca aatggggatg gttttcttca
    14341 attactccta cgctaacaaa agggtgatgt tttacacagt tgatctcatt gaaagtcatc
    14401 caatatttta ctttattttt atagcgtttg aatactgttt cagcgaaacg aacgtaaaac
    14461 tgaataagct ttcgattagg ccatccacca tattctgtaa ccaaatataa cggcatttca
    14521 taatgggaaa gagaaacgac tggctcaatc ccatatttta gacattcgtc aaacacttga
    14581 tcataaaaaa ataatcccgc ttcattgggt gtttcttcat caccatgagg aaaaattctt
    14641 gtccatgcga tagacatccg atagcattta aaacccattt cagcaaataa acggatgtct
    14701 tctttaaagt gatgatagaa atcatttccg tgtcttttag gataataata cttgctgttg
    14761 ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat gccattgatc tgtccatttt
    14821 tctttaggta aatcgctgtc gaatgtatac acatcagaca cagataatcc tttttcatct
    14881 acatcccatg caccttcaca ttgattggcc gctgtcgctc cgccccataa aaatccttct
    14941 ggaaattttt tcatatcgat ccccctaaac ttgctagttt tcttgtttga ttatttttct
    15001 tatgactagt aatgatattt ttgaatctac tactatttgt aacaataacc attgtggtcg
    15061 gatcatatcc ctctttgatt aattcttgca aatctacttc catcaataaa tcgcctttac
    15121 gtactttttt tccatcagat actgcacttt gaaagtattt gccatttaaa ttcactgtat
    15181 caataccgat atggatcagt atctctgctc cttcttcact gactacccca attgcatgtt
    15241 tcgttggaaa aactgttgaa acttccccgt ttacagaact gtagattttt ccgtccgttg
    15301 gaatgatcgc aaacccttct cctaaagatc cactagcaaa tgttggatcg tttacttcag
    15361 ataaatcaat tatttcacct gctgcaggag tacttaacac tatatccttt gaggattctt
    15421 cttcgatttc atccttgtag ccgaaaagaa aagttagcat acaggaactg atcatcgcta
    15481 agaaataact agcaactagc caaacaaatc cttcaccaat ataaatcggg aaagacaaaa
    15541 tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc accagctact ccaccaaata
    15601 tagctccaca tatacaagca atgtaaaatg gtcgtttata tttaagagtc acaccataaa
    15661 cagcaggttc agtgattcca aataatgctg tgataaatgc agataaagat aaacttttta
    15721 ctttcttatt tttcgttttc aaaaataccc caagtactgc tcctgcttgc gcagctacgg
    15781 cagtcataca tgctggacct agcgtatcac gaccgtagaa agaaagattg ttggtcatta
    15841 ctggtacaag tccccaatgt aacccaaaaa tcactaacac ttgccaaaat ccgccgataa
    15901 cagcaccaga taaaacaggg ctaaagttat aaacagctaa atatccagct gcaatcagct
    15961 gacttgcata atctgcaatt ggacctacaa ctaataaaat aattgggacc atcacgatga
    16021 tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg caagcttttg cgaatcttag
    16081 gctcaatata agaaagaacc catacagcta aaattgctgg aataaccgta cttgtatacc
    16141 ttgctagaat cacgggcatc cctagaaatc gcaaggttat gctatcacta tatgcactga
    16201 caatcgtagg ataaacgaga gctgctgcaa taaccatagc gatgaaacga tctgtattga
    16261 acttttttgc agcagtatat gccaaaaata taggcaagaa atagaaaaat gcatcagctg
    16321 ctgcattcaa aatgatataa gttcctgatt cagtagttaa taaattcaaa ctcgtacata
    16381 aggcgagtac tcctttgatc aaaccacttc ctgccaagac gcctaaagtc ggggcaaaaa
    16441 cagcggcgat catgtctata aaagagttta aaatgccttt tttctcagtt cctctctttc
    16501 cactagatgc atcatcttct agtttcattt gtttggataa tacgtcatac acttcattta
    16561 ctgcatttcc tactacgact tgaaacattc ctccagcttc gactacagtg atcacacctt
    16621 ctagttgctc taccttctcc ttatctgcct tcttattatc ttttagggta aagcgtaacc
    16681 ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc tccgacaaat cggacaatat
    16741 ctttcgctaa ttgtgaatag tccattttta cttccccctt gttaattaat gccgtagcaa
    16801 tccttcttac aagataagta tagttcttag aaaacggttt ctccattcaa ttagtacccc
    16861 ttctaatagc gaacgaaact gtacaatagt gtgtatggtt tacttagccg agcaaatcac
    16921 tcactgcttg aaagaaaaca agtatatcgt ttctcttata gtcaaaggag acaaaaaaaa
    16981 cacgcttgat cttcctttgc tgatgtataa gtggtatctc aagctgatac tctgtgattt
    17041 ttgtttctac ttggcttttg ataagacagc acaacaaagt ctcggcattt aacggaagca
    17101 taactaggtc agaactagga gagattagtt gctgaatgga atctatcttt ttatggattt
    17161 ttatttgatt ttcttctttg tagtaatgat caagcagttt tgttttcttt ttttcttcaa
    17221 ctatggtcag cttttcacgc aaaatctgat aaatctccca agattcaaac tcatctagaa
    17281 cactaggtag ataaatcaaa tcatcccact caaaaataag ctcttgctca gtagtcaaaa
    17341 ttgcatcata ttccgttatt ttgtttgatt gatttttgaa aagatacact ggttctatcc
    17401 ggcattcttt gatccacatg ttcatacttt gttgaatctg tttttttagt gtattcaaaa
    17461 tactaattgg ctggttacta acaatcagta tctccccttg ttttcgaaaa ggattcaacg
    17521 cttcggcaag atacaaaaca aaataagcgc tttcagctaa attgggacgt aattgaaaat
    17581 gtattgggaa gaaacgccga attaaataaa tttctaaagg ataacgggag atgatctttt
    17641 gtacaaaatg attcatggta ttatgtccgg catccatcct cgttttcatt tgtttgatat
    17701 gggttagcaa aaattctgtt tcatggaaca ataacgaaac aggaagatct aaaaaacgaa
    17761 taatcgtttg ctcaaatgct cttagattct tctctatttc tttgtttttt tcatcattaa
    17821 tcatcaaata atttaactct aatagtcgat tttcaattgc ttgtttttct tgattggaaa
    17881 aagaataggg tagttctgat gataactttt ttgtgagggt ctctaccatc ggaataaata
    17941 atgtatacct gtttgttttt tctaaaagtt cttctcttcg aagaatggtc aaaacgagat
    18001 accgagaaaa tcgtatgaag tcctctcctg aaacaatata attatatgat ataagaacct
    18061 cttttaatgt cttttggaca gtcggcatga tattggaaaa aattgtactg atttgttgag
    18121 gaaaccttgc gtgttggatc accgtttctg ttccaacaag agataagaaa attctttttg
    18181 aattttcttc agcaatgatt tttagtcctt ttgtcgacga aacttccagt tctaatttag
    18241 gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa tgatacggct gtttttgaaa
    18301 gaaagaaaat gtctgctatc ttttgcatac tgacataccc tttttgaaac aataagtacg
    18361 tcacaatagt tgaagctcgg aaatccatgc tggaatagat tttatgtttc gtcacctctt
    18421 gtatgatttg ctgtttagtt tcagattcaa ttgattctaa aaaataacct gaacgtttat
    18481 ttgactggat aatgattttc ttctcgtaga tagcaagcat atttttgatt tcagtttgga
    18541 tcgttttctt gttggtacct aaagcttcag ctaattcttc gcttgttatc caatgattct
    18601 tatttcttaa tactacaaga atttggagtt gtcgtttatt taagtccatt tgcttacacc
    18661 tcctctttgt tataaacata caggaaaaac ctctcaaatg acaatagtca cttgcagagg
    18721 tttaaaaatc atttgaagaa agatctatat tcaaggtttt taccattaga ctggataatt
    18781 tgtttataat attcaaaact atcttttttc aatctcctaa agcttccgct cccatcattt
    18841 tgtctatcca cataaataaa gccatatcgc ttcctcattt cccctgttcc tgccgatacg
    18901 atatcgattg gtccccacca taagtaacca atgatttggc aaccatcttt tattgcctca
    18961 gcaatttcct gaagatgtat ttttagatac tcacaacgtt ttggatcgtg gattcgattc
    19021 aattcatctg gtgcttcatc tagtccaatg ccattttcaa ctatgaataa tggtaattca
    19081 taacggtctg tcaattcatt catgacataa cgaaacccta gaggatcaat tggccaactc
    19141 caaggttcgg gagatttttc cttcaaaaag ggattatcga aaccatttgc tccgccagta
    19201 tctacgcgca tttctgcttc ttttttatag acagcgctac gataataact aaatgcaata
    19261 taatctgccg tgttagcttg caagcactgt tcgtctccat ctaacattac tggtgcacag
    19321 tcttcttcct tccatgtcct gtaaatataa gctggataat gccctcggca catgacatcg
    19381 gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa atacattctc tggatcacag
    19441 tcatatgcat aagtcgctaa tgcagaaaag ctacacataa tacccatctt agcatttgga
    19501 tcgattttct ttaataattg agtagcacgg gcgttcgcta gaaacatatg atgacaggct
    19561 tgataaatca ctttttttgt tagtgtagca atgggttcaa gtttatctct agcagggaat
    19621 gtaaccaatc cagcagctgc ataaggcata cgaaaagcat tattgatctc attaaaggtc
    19681 atccaatatt tcactttccc ttggtagcgt tcaaagacgg tctgcgcata aaattcaaaa
    19741 aagtcgatta attttcgatt ttgccacccc ccatactctc ctaccaatgc taagggggtt
    19801 tcataatgac taagagtaat tactggctcg atatcatatc gatttaatgt attgattagt
    19861 ctgtcataaa atacgagacc agcctcattt ggcttctgtt cgtctcctct tggaaatatt
    19921 cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta actccttcag taaacgaata
    19981 tcctcttcaa atcgatgata aaaatcaatc gcttcatgag aaagataatg gagtgattcg
    20041 tctaaagcaa tctcccaaat ctttttttct tcattccact gaatactagg atgctggttc
    20101 atgatcccga taagcgtatc tgtcacatta ggtaatttgc cgtcttccaa ccatgcacct
    20161 tcacattgat tagcagctac tgctccgccc cataaaaaat tttctggaaa tatttcctga
    20221 tccataacta tctctcctcg ctatcaacaa tttcttactt gaagtatagc tcgattcatc
    20281 aaaacaagat attctaacta tttcggcaga agagaagaaa aaaattgaat gctactcttc
    20341 atttttaata tttatatata acaaatacat aagacgatcc ccgaaagaaa acactcgtta
    20401 accatctaag caaacgattt attttacttc caacacaaat gcttcataag gtcgtaaatc
    20461 aactttgccg tctggtaact gtttcagagg ataatttgac acaataaccc ttaaagcttc
    20521 acgtggaata gtgaacgtct gcttttcact ggacatatta caaataacga gccattgctg
    20581 gtcttcatat atgcgagaat aggcaaagac atgctcaggc gtcttttcca ctaattcata
    20641 gtctccccag acgatgatgt catgttttct acgcaaatcg atcaatttct tgtacatata
    20701 aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg atttctttat aatttggatt
    20761 gactcgaagc catggaattc cagtagtaaa cccagcatgt tcacgggcgt tccattgcat
    20821 aggcgtccta gcattgtctc ttcctttcgc cttgattgat tccaagattt cctcttttgt
    20881 aaatccagaa gaaatccttt cgttatacat attgattgtc tcaatatctt ttgcttccgc
    20941 gatatcatcg attgggcaat tcgtcatgcc taactcttct ccttgataga tataaggggt
    21001 gcctttcatc atatggagca agatagcaaa catcttggca ctttcttttc gatacacatc
    21061 gtcatttccc caacgagaaa caattcgcgg aagatcgtga ttattccaaa ataaactatt
    21121 ccatccttca tcacctaaag atgtttgcca tttggataat acttttttca gttcagagat
    21181 actcaagggt ttcaaatccc atttgtcttt gccttcttgc tgatctaatc ctatgtgttc
    21241 gaattggaag accatggata attcatttct tttaggattg gaataaagtt tagcgatttc
    21301 ggtagttgct ccccatgttt cgccaacagt catcagattt ttgtcaccaa aagttgcttg
    21361 attcatttcc tgaagatact catgcagttt aggtccatta cttgtgattt ctttatccgg
    21421 ttctttgcca atcatatcga tcacgtccat acgaaagccc ccaatacctt tatcgatcca
    21481 gaaattcatc atttgataaa tctcttggcg aacctgttta tttttccaat tcaaatcagg
    21541 ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt ttttcatcca actgccaagc
    21601 agaaccactg aatattgagc gcaatctatt aggctctttt ccattgaccg gatcacgcca
    21661 aatataatag tcccgataag gattttcttt atttttacgg gcctcaatga accacggatg
    21721 ttcatcagaa gtatgattca ccaccagatc catgatgata cggatatttc ttttctttgc
    21781 ttcttcaatc agttcttcca tttcttccat cgtaccgaat tctgccatga ttgcttgata
    21841 attactgata tcatacccat tgtcatcatt cggagactcg tatactggag aaagccaaat
    21901 tgcatcaata cctaaatacg ccagataatc caacctggaa ataatccccc gcaaatctcc
    21961 aataccatct tgatttgaat cttgaaaact tcttggatag atttgataaa caactgaatg
    22021 gtgccaccat ttttgttcca tgattttcct cctataaatg gatgtttcta ttttttgctt
    22081 aatcatttat tttagtctct ctcactaaaa attgtaacgc tttcaaatag ctattgcacc
    22141 ttgttatcgg taacagaata aaacaaaaaa acagctgagg aaattccctc aactgttttt
    22201 tgaaaggatt gatttatgca gggaagaatg ctgatttcac aacttcttta taaacggtgt
    22261 tcactcagct gtcccttggt attagctcaa aaaacggcaa aatataagaa actatttttt
    22321 cgtttttttc tctaatactc aggccagaac gctgatttca caacctcttt atttcacatt
    22381 caatatccac atgaatccca caaatacaaa gaacagacca tacatgattg gagatacttc
    22441 ttttcctctt ttagctgcta acatggtaat tggatagaag ataaaaccta atgcaatccc
    22501 atctgaaata ctataagtca aaggcatgcc gatcaagatc aagaatgaag ggatcgcaat
    22561 ctctaagttt ccccattcga tttgtcgcaa agattgtgcc atcaatactc ctaccataat
    22621 caatgctggt gcagttactt gtgaagtaac aactgatagt aatggagaaa agaacaagcc
    22681 taacaagaag aaaatccctg tagtaatagc tgtgatacct gaacgtcctc caacggcgat
    22741 accagctgat gattctacaa atgcaccaac aggagaagta ccaaataagg aacccgcaag
    22801 catagctgtt gaatcagaag ctaaagcttt ccctacacga ggcatcttgt tgtctttcat
    22861 gaaacctgct tggtttgcta atccaactaa agttcctgct gtatcaaaga aagtcacaag
    22921 caagaatgtc agcactacga cccacatttg aagagaattg atgtccccta catgttttaa
    22981 tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca acaatttcag aaggcattgg
    23041 aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc atcccgatga agatgccacc
    23101 tggtacacgc cgaacaagca agatagcagt tacgactaat ccaaaaatcg tcaaccaagt
    23161 agaaccaacg ttgagtgatc ctaatcctac taatgtagat tcattcgaaa cgatgatccc
    23221 accttcgctc agaccaagga aagcgataaa tagaccgata ccgccagaaa tcgcatattt
    23281 caaatctgct gggatcgcat caatgatcat ttcccgcagc ttgaagattg tgatcaaaat
    23341 aaaaatcaaa gaagcaacga atacgccggc taatgctgtt tcccatggaa tccccattcc
    23401 taaacaaaca gaataagcaa aaaaagcatt gatcccaaga gcaggtgccg ttccaattgg
    23461 ataacgggct aataccccca ttaaaacaca gccgatcgca ctggctaatg cagtcgcagt
    23521 aaacactgct ccttcatcca ttccagaagc acctaataca gttggattta caaataagat
    23581 ataagccatt gagataaatg ttgtaaatcc tgccagtacc tcacgtttta ccgtggtgtt
    23641 caatttttct atttcgaagt aggaaagtat tttttccttc atcttccatc cccctaaatc
    23701 cgaacattat aaataaagtc cgttaaaatt tcgatttatt aataaaacaa cgtgttttat
    23761 catatactaa aacaaaacat aagtaaacaa aaaattcgga ttttaagcaa aatccgaacg
    23821 ttccatctga ttaaatccct ttatctcaaa gttcatgaac attcactttg gattacaaga
    23881 atttctttat tgtgttaata aagtttcttc attctagtct caaaaatcaa tagtgtgatt
    23941 tgattttacc atttcgtttc tgttcttctt tgatgaattc ttttgtatcg acaggattca
    24001 gattatttag tccgccaaaa cctgtatcga ccatttttcc ccagcctttt gtcttctttt
    24061 ttcctgattt gagattcttt gctcgaagct tctcactatg ttttgctcgc cgatacttca
    24121 aataaccttc taatcttccc attagatcca ctgtttttcc tcctttttat tcaatcagac
    24181 gactcagctt ttcctataac aaaataattg ccttcagggt cagaaaaatt gaaagtcaag
    24241 atgccattgt tatctgtgat ttctcctggt tcttccatgt tctcgtagat agtttcaaat
    24301 tcatccgtaa aaaatactaa agaaggcggt ggtcctaata cctctggtga aaacttctgc
    24361 acaaatactt ttgggaatac gcctaattct aattcttttg agatgctgag tacaatactc
    24421 ttaaattctt ctggcaattc gattgtttca gaaatttctg caccaatttt ttctacaaag
    24481 aatcggcaaa tcatctctac gtcattgaca taaagcatca cacgtgtttt ttgtatcatc
    24541 atttgaccct tctttctatt tgattttctt tcctgtctat aaactgattc cattatatca
    24601 cgaaagcgca aacaccttgt gtttgatact attcaagaaa aataaagcaa tagtttctag
    24661 gattgctttc ctccacaaac tttttttaca aaaaaaaaac ggcaatgaat gccgctcttc
    24721 ttatttcgat tcttttataa ttctgcttct gattcatctt tggttagtgt gtgtctaaca
    24781 ctagttacgc caaatgtttg atcgattttt tccttcaacg cttcgattgc ctgtgcgcca
    24841 cgtgccgctt gttcagcatt gatggattca atgaccagca ccgctgcttg tgtttcttcc
    24901 gtcagcatcg ttctttgggc ttcacgccag ttgagacagc gacagatcgc tccttgttca
    24961 tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg aatctgcacc taaaggcagg
    25021 aatgattcgc caccttgggc ttttcctaaa tgcagatttc ctgcgatctt ttcgatatct
    25081 tctccgccgc aaggtacgcc aaaagacaag gaaatactat tatagatatc tacaagcgga
    25141 ttgattggga aaaattcccg ttcttgattt gcacgtttca gtaaagcttc aatagaagaa
    25201 cgtgcacctt ttttagtctt gaatgtggta aatgcctgac gccactgagc aatgacttcg
    25261 ttttggctga atgtttcttc tgtaaggtaa tttcttgctt cttttgctgc ctcattcaat
    25321 aattgatgat acgtttcttc actttctttt gttacgtggt tatcgatacc atttacggat
    25381 aagatttcga tggttgcttc aggaaatact tcccagaaat tggtatccac tattactttt
    25441 ttcatctgtt cacacctctt gattagaata attgcttgat gaatagatag tctgtttggg
    25501 gatcatctcc catataaaaa acatgttcgc tgtatttgat aaatcctttt ttacgataaa
    25561 aagcgagcgc aacatcgttg tgttcccaaa caccgagcca aatggctgtt ttttgctttt
    25621 cttttgcttt ttcaatagct gtatctagta aaaatgtacc gataccttga tgtttaaatt
    25681 tttttcgtac atagattcgc tcgatttcta aaaaatgatc agccatttcc tcagattgac
    25741 tcgttcctgt atttagtttc aggtaacccg caggctcttg atcgatactc actaggaaaa
    25801 aatcggtttc tttatctttt agctcttctg taagtttttc tagtgcataa gcttgtgtca
    25861 agtaatcagc taaatgctcc ggtgaattat cttttccaaa tgtatctgta aatgtttcga
    25921 tactaatttg ttgtagtaag tctacatctg aaggcgtcat ttttcgaatt tcgtatttat
    25981 tcacggcttc ttcctttcaa tagatccttt tattgccttt tttgacaaaa ttccaatctt
    26041 cgctaacatt cttgcatact ttatttaaaa gatattccaa ttgttttgct tcttcgtcag
    26101 aaagaccatt taatgcgact gcattggagt agttgttttc tcgaatgatg aaaggataga
    26161 tttctgctcc ttttttagtc ggatagagtt tcttgatttt tttattttct ttatcttcca
    26221 aacgttcgat catcccattg gattctaatt tcttgattgc tcgggcagtc gttgtacgat
    26281 ctactttgat catttctgct agtttttctt ggatgattcc aggattttcg caaatacgta
    26341 ctaaataaag atactgtcct cttgttaaat cgacttcttt gaattcgata ttgctaatag
    26401 aatctagcgc tcgggcaatc attccgatgt ctcgaaggat ttcagccatt tcatcccacc
    26461 tttattttgt ttgtaagact agttcacctc tttttgttgc aaatgcaact attttcaata
    26521 aaaaaatcaa gttctttttt aataactagt aaagtatatt cttttcttct tttacgaaaa
    26581 agctcaatca caatagatct ggtttttgtt ttctaaaata agtaactgtt tcttcgttgt
    26641 tcgcttttct gatagctttg gcaactcttc tatactaaaa aatcccatgt tggaagtttc
    26701 attattctca ataaacttgg cctcttcacc gtggatcgca caagcaaaaa caagtttata
    26761 atactgaaaa agctgtggaa tatctttttg tttattcgta tcaaaaactg ctcgcaactg
    26821 agtagtttct actgttaatc ctgtttcttc atagacttct ttacgcacat tttcttcagg
    26881 agacaatcct atttcagcaa atccaccagg aagtgaccat tctttcgtcc gtttatcttc
    26941 gattagtagg accttgccat cttttttgat ataggcacga acatctactt ttggtgttgg
    27001 atgtccttct ccaatcgttg tgagcgcttt tatttcttcg aaagtttctt ttcctatttc
    27061 actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa cgctctttat caaatacatc
    27121 ttttccataa tatagaccag cttgagaaag tgcgagtagt cttttgtatt gagccaactt
    27181 cttgttcatt ctcttccctt cttttttagc aaatgtatga ctatgtaatc aagtatagaa
    27241 gactggttta attacggcaa ataaatataa tgaaatctgc aataaataaa agaatgttaa
    27301 aaaactcgag aacaaaagac attcgacttc tctggggctg tgaataaatg gcgttcaaaa
    27361 gcttgcatct gcggtaataa gccccaccaa acgaaaaata tgacgagcta ttcttgtctg
    27421 gctgttctta ttaattgagg caggacagct ttttcacaac ctccccacta aacggtgttc
    27481 tcctaccaac tcctcggtca caagtcacaa tattcatcaa acatgagaag ctgttttttt
    27541 gaaattgctc cttgtgactc ggagctgaac gacaggctca cgacctctcg gtaaacagcg
    27601 ttcaaaagcc aatttttcga tattaagcca tttctttgtt acttattgtc attgatttct
    27661 ttttctaatt tatccaatag tggagtgtaa tccacttgag tatagtctgt tacatcaaat
    27721 tcatatagtg ttcctaactg gaatttgtca tattttcggt cggcgatgat ctttttgaat
    27781 gcttctttcg taatatgatt ggtccctttc gttcgatctt ccaatacgtc accatagtga
    27841 taatgatcca tgatatagct caaatgacga tctgattcac gatcacgttt gtaccgacgt
    27901 tgccataaca cttcaaagtc tgctgttagg cgaatcgtga tcacctgata tccgtatcta
    27961 tctgctaatt cttggagtcg tgctttttgc ttatcactaa aaggatactc ggacacaatc
    28021 actttctttc ctgcttccat atacaaatca agtgctttgt aatagaaagg ataaactttc
    28081 gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc cgatggattc tgcatagtat
    28141 tccttgattt catcgagcgt gatggcatac atatctggaa atcgttcccg tagtttattc
    28201 ataagatatg tttttcctgt accaggacta ccagccagaa gaatgaaata ctttttcatc
    28261 tcatttattt cctaagttaa ttggactttc caagttcata aacagtccaa tcttatgctt
    28321 gacaatttct tttactgctt catttgctgg aatcacatta tggcgaagag acttgttgat
    28381 ttctgtttca ctaaaggttt ctttagctac tttcgtccag ttgactaaaa gctccgttcc
    28441 aacattgaat ttgcggatcc cgttattgat caattcagga taatcttctt ctttcacacc
    28501 tgttcctcca tggataacta gggggacatc aactactgca tcgatttctt tcagcaaggg
    28561 aatgtttact tctgtttttg atttgaattg tccatgattc gtaccgatag caatagctaa
    28621 tgcatccacg cctgtagctt ctacaaattt cactgcgtct tccggtcttg tatatacctt
    28681 gtcattttca gcgacatgga ttccttcttc tgtaccgccg attgttccaa gttctccttc
    28741 tacggaaaca ccgtgcgcat gggcatattc tactactgct tttgtcttca ggatattttc
    28801 tttgaaaggc agatgggacc catcatacat gacagaagta tatccgctgt cgattgcttc
    28861 tttgatatca tcaaagtctc gggcgtggtc taagtgcaag actgcatcaa ccatttcttc
    28921 ttctgcaata gctgtcatta cattgactaa cacatgcatg ccgatatatt tagcggtatc
    28981 gacacttgtt tgaataatga tcggcgaacc catttctttt gctgcgccta gcatagcagg
    29041 aagcatttct aggttatgcg tattaaaagc tccaactgta aaattcaact cttctgctgt
    29101 ttttgttact tctttcaatg ttgtatacat cttttattgc caccttatct ttttatttgt
    29161 ttcctttgat cgttacttgt tttgcaattt gtcgcatctc atccattttg cccatgtagt
    29221 aatcgatccc ttgatcatca ccagcacgag cagcatctgc acgcttctgg ttatagaggc
    29281 tcatcagttt tttataccca tctccgatcg tctgtttatt ttccaaactc ttttctaaat
    29341 attggatggc ttgatcgttc acatacaatt cagaaaattt aagtccaact tgttcataaa
    29401 gtttcgctaa tttatgctta tcttgggtag tggaaatctc ttgtttcaat tgtgtaatct
    29461 ctgattgaat cttttcggtc gcttctggcg atagggcttt ttcttctttt gccagaactt
    29521 ttttcggttc tttttctttt ttcttaaaaa atccaaacat cattttccct actttcaatt
    29581 aaaatgcttt caaaactggg cttaagatcc aggcatataa gagtgctgcg gctactgtat
    29641 ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt aaagatcgtt actagcaaag
    29701 cgggcaataa tgtaataaag aaaccatgag caataccgcc aatgatcgct cctcggcgtc
    29761 cgccaactgc gttgccaaat atccctgctg tccctccggc aaagaaattg gttagcatac
    29821 caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa catggcaata atcgtaccaa
    29881 tcgttgtcgt aatgaaacct aaaatgacag catttgggct ataaggaaag aaaactggac
    29941 aatctaaggc agggatcgca tcaggaacta atttcatagc tatccctcga aatgccggca
    30001 cgatttcacc taacagtaga cgtacaccag ctagcaatac atacacaccc actacgaatt
    30061 ggatggcttg taaaaaggca aacatgatat agttttgatc tcctgataat tcagaagcga
    30121 atggttcgcc tgcaaataaa acagtgatga tatatagcgg gaccatcacg accatgacag
    30181 acaaataagt atcttgcaga aattcgaaat gtgtcggcaa cttgatatct tcgatcgact
    30241 ttttattttc gcctttctca ccaaaaagct tagcaacacc ggcttcaaat aagtacccga
    30301 tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt gattttacga atgatcggtt
    30361 gcgctactgc cggcatagca atggcgaaac aagctccgat aaaaccaccg accaagatca
    30421 atacgatccc tcgcagaccg gcaaaatagc caaagactgt cgtcatcgtt gccatccata
    30481 aaattgcttg accagttaaa aaaatgtact tccattttgt gaaacgagcc aaaataatat
    30541 tgaatacaaa aatggctaag aacgtcagtg caatatctct acctaaaccc aaatcattca
    30601 ttgcttgacc attgatagat tcaatagaag ggatgatccc ttgcatatga aatccttcag
    30661 taaagatttt cccgaaataa gttaaacttc caacgatgat gctcgaaccg gcactcaaca
    30721 cttgaaatcc taggagtgtc tttaacgtgc cagagatgac ttgtcctgct gatttcttct
    30781 gcagtagtag acccaacata gcaatcaatg caatggtgat cgatgcctga gtcaaaatat
    30841 tttcgatgat aaaattgata acgcccatgt t
//
LOCUS       DACGLI010000037        29948 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.038, whole genome shotgun sequence.
ACCESSION   DACGLI010000037 DACGLI010000000
VERSION     DACGLI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.038"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(26..328)
                     /locus_tag="IXT22_001783"
     CDS             complement(26..328)
                     /locus_tag="IXT22_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863133.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="IXT22_001784"
     CDS             complement(353..2446)
                     /locus_tag="IXT22_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4863134.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="IXT22_001785"
     CDS             complement(2935..3699)
                     /locus_tag="IXT22_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAQ4863135.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="IXT22_001786"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="IXT22_001786"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAQ4863136.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="IXT22_001787"
     CDS             complement(4704..5780)
                     /locus_tag="IXT22_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAQ4863137.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="IXT22_001788"
     CDS             complement(5804..6397)
                     /locus_tag="IXT22_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAQ4863138.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="IXT22_001789"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="IXT22_001789"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAQ4863139.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="IXT22_001790"
     CDS             complement(8067..8366)
                     /locus_tag="IXT22_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAQ4863140.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="IXT22_001791"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="IXT22_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAQ4863141.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="IXT22_001792"
     CDS             complement(10121..11032)
                     /locus_tag="IXT22_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4863142.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="IXT22_001793"
     CDS             11152..12009
                     /locus_tag="IXT22_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4863143.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="IXT22_001794"
     CDS             complement(12196..12558)
                     /locus_tag="IXT22_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863144.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..14343
                     /locus_tag="IXT22_001795"
     CDS             12904..14343
                     /locus_tag="IXT22_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4863145.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(14350..16902)
                     /locus_tag="IXT22_001796"
     CDS             complement(14350..16902)
                     /locus_tag="IXT22_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAQ4863146.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(17016..18347)
                     /locus_tag="IXT22_001797"
     CDS             complement(17016..18347)
                     /locus_tag="IXT22_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4863147.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(18313..19791)
                     /locus_tag="IXT22_001798"
     CDS             complement(18313..19791)
                     /locus_tag="IXT22_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4863148.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="IXT22_001799"
     CDS             complement(20096..21931)
                     /gene="tdc"
                     /locus_tag="IXT22_001799"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4863149.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            22401..23828
                     /locus_tag="IXT22_001800"
     CDS             22401..23828
                     /locus_tag="IXT22_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4863150.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(23920..24285)
                     /locus_tag="IXT22_001801"
     CDS             complement(23920..24285)
                     /locus_tag="IXT22_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4863151.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(24282..24647)
                     /locus_tag="IXT22_001802"
     CDS             complement(24282..24647)
                     /locus_tag="IXT22_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4863152.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(24839..25087)
                     /locus_tag="IXT22_001803"
     CDS             complement(24839..25087)
                     /locus_tag="IXT22_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863153.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            25086..25214
                     /locus_tag="IXT22_001804"
     CDS             25086..25214
                     /locus_tag="IXT22_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAQ4863154.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            25271..26965
                     /locus_tag="IXT22_001805"
     CDS             25271..26965
                     /locus_tag="IXT22_001805"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAQ4863155.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            27032..27238
                     /locus_tag="IXT22_001806"
     CDS             27032..27238
                     /locus_tag="IXT22_001806"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863156.1"
                     /translation="MFLIWLDLLPQMQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFL
                     TWLDLLPQMQAFEHRLPRGYEKGV"
     gene            27616..28749
                     /locus_tag="IXT22_001807"
     CDS             27616..28749
                     /locus_tag="IXT22_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAQ4863157.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            28780..29100
                     /locus_tag="IXT22_001808"
     CDS             28780..29100
                     /locus_tag="IXT22_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863158.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(29129..29593)
                     /locus_tag="IXT22_001809"
     CDS             complement(29129..29593)
                     /locus_tag="IXT22_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863159.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(29725..>29948)
                     /locus_tag="IXT22_001810"
     CDS             complement(29725..>29948)
                     /locus_tag="IXT22_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863160.1"
                     /translation="VSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAA
                     VNLVLSILIYLPFVKVATIQERRKEALDA"
BASE COUNT         9032 a         6212 c         5170 g         9534 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg acattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aactttttta
    14341 tagtaacggc tagcgactgt attctctagc tgttttttct tttttgcgaa acagtttgtt
    14401 catgatccct ttttctattt ctacaactaa gaatagaaga atcacatttg ctccaatcaa
    14461 taactgttgt gtcatcgtta aacttactgt accgatcagc tgctggccga ctggtagaaa
    14521 aataaccatc ccttgcaata aagcaaggat acctaatgaa agaaaaagcg ctttgttttg
    14581 caaaagacct tggttcaatg acggcttgga caactctctg caattgatca tgtaaacagc
    14641 ttgagctaag acgatatttt gcagaagaat ggtttgctgt aagctttgcc cttcaaactg
    14701 catagccaat aaataggcag gaaccatgat cagtagggag acatagatga tccgaaacaa
    14761 atgataacca gataggattc cttgctttgg atctcttggt gggcgcttca tgatttctgg
    14821 atctggcgac tcgaacccta gtgcataaga taaagtgatt gtcgttacca tattgaccca
    14881 taaaatctgt actggggaca aaggtagcgg gcgattcagc ataagtgccc aaatcaagat
    14941 caatccttga gctaatgcag ttggcaagaa gaaattgatg gttttttgca aattatccaa
    15001 aatccgccgg ccctctttta cggcttttgc aatcgtatgg aaattatcat ctcctaaaac
    15061 catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcaa ttcctacatc
    15121 ggatcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga cgatttctcc
    15181 atttttctgc aaagctttaa caattcgcag tttatgttct ggtgtcgttc gagcaaagac
    15241 atcgactatt ggcacttgct gaatcaactc ttcatcagac ataagatcca aatcgatccc
    15301 ttctaaaact ttggcagtat gttttaagcc aatttgttcc gcaatcgctt ttgctgtgtc
    15361 tttgtgatcc cctgtaatca ttttcactga gatccctgct tgttggcatt cctttacagc
    15421 tttgactgca ctttcttttg gcggatcgat caatccggcg atccctgcaa aagttaattg
    15481 ggttaaagtc tcatgcgtga gttcctgttt cgaatctact tttttataag caaatcctaa
    15541 aacacgctga ccttttctcg caaattctgc agctgtctga ctccatgctt cttgttctgc
    15601 agaagaaaga gttgatttag caaataatac ttctggtgca cctttgacgt aaatcaccgc
    15661 tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagaactga acggaatctt
    15721 tgcttctatt tttttcaaag gtagattggc tgtttctgtg tgtcgaatca gcgcaacttc
    15781 tgtcggattg ccacttaaat tttctgtttt ctgttcttct tttgttttta attcctgaca
    15841 gtttttcata atggacaaca cgcaggcttc ttcttttgca gctacatcca caactgtcat
    15901 ttcatttttt gtcaatgttc ctgtcttatc tgaacagatc actgtcatag aacctaatgt
    15961 ttctaccgaa ggaagtcctt tgatgatcgc cttttctttt gccatttcat gtactccaac
    16021 ggatagaatc atggtcaaaa cagctggcaa tccttcgggt accattgaca ccaccaaagc
    16081 aatcgtagcc gaaagaagga tatgccaatc cataccatat cgaaatgtcg taaaaataac
    16141 taagaatagg ctcaaacaaa gaatgccttg aaaaatttgt ttgtttaatc ggttgatttt
    16201 tttaatcaga ggcgtcgttt gttgttcgac cgattgcaat gcttgattga ttttaccgat
    16261 ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt gtacaagcgt
    16321 tcctgaaaaa cccatatttt tctggtcgcc gatcgattct tcttctgtca aaacggcatg
    16381 acttttttca gatgcttctg attctcccgt caaaatcgat tcttccacta ataaatcatg
    16441 tgcttcgatt aatcggatat ctgctggaac gacatctccg gcacgtaaga caatgacatc
    16501 tccttttacc agttctttcg cagggatttt ttcttgcatc ccgtttgata gtactatcgc
    16561 ttcttgtccc atcagctgct tcaaaccatt caatgattct tccgcttttc tttcttgcca
    16621 gtaactaacg agtccattga cgatcactac gaataaaata atacttcctt caatatattc
    16681 actagaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca gatcagtaaa
    16741 atgctttgct atttttttcc atcgttttgt ctgctgcctt gcttttattt cattatatcc
    16801 ttgatcagtc aggcgtttct gtcgttcttc ttgcgacaag ccttctgttg atgtttgata
    16861 gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc ctcctgttta
    16921 attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat ttcagggggg
    16981 tctgaaataa ttcgttttgc aaaatgtatc tgggcctaac tgatatttct attgcttatt
    17041 cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg aataaagcgt
    17101 gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa caaagcaaga
    17161 tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac atgtgcacac
    17221 aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa aagctgaaaa
    17281 aacaatcgac tatcagctac aaaaaaatgt agacaaagac cggcaaaaaa taacattcct
    17341 gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa ccaatggggc
    17401 aaactttttt cttttgctgt ttgatataaa atcctgctag tactgtagac tgcactattt
    17461 gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc gccttggcaa
    17521 tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca atgccatgga
    17581 acaacaaata aaatcgacaa aatcgttcct atatagaaaa agagaatacg ccaaggcaga
    17641 cagttgattg cttttttcaa attcttttgc ggatcacttg tctcgccaac ggttaagccg
    17701 atcatttcaa ttccagcaaa actgaataaa accataggaa atgagactac cattccagca
    17761 aagccaaacg gtagtaattc atcgatctgt ccaaaatttt ctttgattcc gatagactgg
    17821 gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa aatccccaag
    17881 atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc aacaaggttg
    17941 actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac atgtacaaac
    18001 cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc aagccagcaa
    18061 agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata gtcaacgaaa
    18121 tcactgatag agttaaatgt actatttgct aaaaataaat cacccatggc ccgcatcaaa
    18181 ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc tgctgatgca
    18241 attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa tgcgattaac
    18301 tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa gttcaccttt
    18361 ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta ttttttcaat
    18421 acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta gattgatcca
    18481 tgttccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata aaacaataac
    18541 gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa atggtcgatt
    18601 caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga catagacgat
    18661 acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga cgccaggaat
    18721 cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa taacggattt
    18781 ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg caccttttct
    18841 agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt ggactgctac
    18901 accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac caagaatttg
    18961 gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt ttggtacgac
    19021 atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta acgcggcaaa
    19081 tactccgcga atatacgttt taactggatt ttccaatcga gtgatataca cagaggacat
    19141 ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg atgcagtcgt
    19201 agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg gtacgatccc
    19261 aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca cgtacaatcc
    19321 taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat tcaaaaaagt
    19381 gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca aaccaagcgg
    19441 cacattatcg ataatattac caaacaacgg agcgagtgct gaagcgacca tcaccatccc
    19501 aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt ttcctagagc
    19561 attcgatacc caaagttctg gaccaccttt ttggggaaac attccagcaa attcaccaga
    19621 gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa aaatcatcgt
    19681 ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg cgcaggtcat
    19741 tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca tctttattcc
    19801 ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga acagaaatga
    19861 caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt gaacgatctt
    19921 agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt ttataaaaaa
    19981 gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt tgatgaagca
    20041 aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat cagttctatt
    20101 ggatgatttc gtttagtttc ttttccattg ctttggcgat tttttttgta taaaaattga
    20161 aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga gtgattttct
    20221 gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga atcggagaat
    20281 caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca ccataaacat
    20341 cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg atagcgttca
    20401 aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca ggatgattca
    20461 atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg agaaattctc
    20521 tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg gtcacattca
    20581 atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct tttgatcctt
    20641 ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac acatatggcg
    20701 cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct ccagcagcat
    20761 aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct gaaatagctc
    20821 tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca tgatgttctt
    20881 caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt agaaacagtg
    20941 aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc ccttcatctt
    21001 ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct tcttctgtcg
    21061 ttcctacgac agcaaccaca cctagaattg ggattttttg tccagctaat tcacgaattg
    21121 ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata gcaaccatct
    21181 gatctaagcc gactccgcaa atatctaacg ccttcatcca agaatagtgt tttgtttgag
    21241 ggaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa gctgctttga
    21301 cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct tcaacagata
    21361 aattcaaaag ttcccactca gacatttttt tcactttttc aggcagcact tccttgacag
    21421 ctaaaggaat cgatttgatg caacgggcgt accataatcc ttcaagatta gcaatagaac
    21481 catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca aaatcctgtc
    21541 ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca ttatttgggt
    21601 tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca gcattcattt
    21661 gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat cgctgactga
    21721 cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga gtgagcttat
    21781 ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat ccaagatgtt
    21841 catctaccat cttgttcaac aacattttat aaactggtcc attttcagct ttgtcgccta
    21901 taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt tgttggtcaa
    21961 tgtcttgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc aaaaatgaga
    22021 attttttttt tataacatca aatccacgta gatttttaca aacaaaaata aataaagtcg
    22081 gatttttctg ataattcaac gcaaaaaagc gaacaatttt tcaataaatc agtcttctaa
    22141 aatagataac ctaaaaaaag cgaacaaaca aataaaatga ctgtccttca ttcactaaac
    22201 atatttttat ttttttatat tgttaaaaat tcgcaattta ttttttaata gaattatctg
    22261 ttttccaaat tttataacat aaaaaacctt ttttaacggc atttatatgc tttttcagaa
    22321 attaactgat gatttcaaaa agaaaacatg tcataatatt tcccatattg tgcaaaaaaa
    22381 tacaaggcgg aggctctact atgattgaag aatatattga gaaaaatatt ttaagacagc
    22441 tgtttttatg tgggcaattc tatgtaaata aagaagtcaa tctagaaaag ctctccaatc
    22501 tcctgcatgt ttgcaaaacc actttactca atgatatcaa taacataaaa aaagaatttg
    22561 aagaacagat cgcttataca catcgggaaa aggaccgtta cactttatat ttttcagaac
    22621 atatacctcg atgcaagatc atgcagcaat tgtctcaaaa ttcgttgttt ttaaaaactt
    22681 gtctgcttta tttggaagaa gatgaacctg attatcttca attaactgaa tgtgaattca
    22741 tctctgtcag caaagcttat tcattaaaaa aacaagtatt agcttatttt aatgactgcg
    22801 ggatcgaaat cgaccgctac tcccctcgat tcactgaaat ggaaagacgt ctgctgcttc
    22861 ttaatgtgtc gtatcgttta ggcggtttta attcttggga gctacctgaa tcgttttttg
    22921 aacgtgccga tcgtttcatt gaatccgtaa cggaaaatag tggcagattt tatgataaag
    22981 aaaataaaga aatcttatcg attggttttg ctatcagttt cctacgccag caagtgtgtg
    23041 ctgtgacaat agattcaaaa tttatcgaag aaatcaaaaa acgtcctatt tacaattatg
    23101 tcgaatcagc atgggaaaac actgatttcc aaacctatta taaaaaagaa gaattcgcct
    23161 ttattttgac actattcaat ctttgtaatt atggtttcca ttcttatcag ttgattgcgg
    23221 aagactttca acagctacac caagtgttta ttgacaatac tcccgaaata aaagaactag
    23281 ttgctacctt tgaatctcac ttcaatcaag aattattcgg aaaccaaccg ttcgaacgtg
    23341 cgctgattca tctgatgcgt tcggcttggg ataactatca attattcatg ccagaaaaat
    23401 tttatctttt aaatgaggaa cagacaaatt tatataaaga agtccagaca attttttcca
    23461 gctggtccag ccagttacct tatgatctac ggttgaatcc taattgcatg cgggcttttg
    23521 tgatcgaatt gagcggaatt ctccgtctga caaaagaaca tctgactatc tatatcgtca
    23581 caaattcgga tgttcattat ctgatttatc gggaagcctt ggaagctgta actactttcg
    23641 attttcaagt tgcaccaaca atttattcaa gtatatctga tataaagaag tatgcgcagc
    23701 agtcctcaaa ccgggtatta tgtgaacgta cattatatac accagatgcg gtccaatatg
    23761 aaaatattat tcctatttcg atcaatacga tcgatcgagc tatcatttca gctgtgcaaa
    23821 acaaataagg ggctgtgaca aaaatcatgt cacagcctct tatttgttga agatgcccat
    23881 ttctgtaaca atctcttgat acacgtcagg ctcacaacct cacttatttt ggacatctac
    23941 gggtccgatc tctttattta aaaaataaga aatgatggtt cggataacta ccaacgccgc
    24001 tagttggaaa atatcctgca aggtaggttt gataatcgat tcgatgatcc cagctgaaac
    24061 aagaatttcc aaacttagaa gtatatagcc tcccaacatc tttttaatag cattgttctc
    24121 gctgactcgg tcgctttgca cttttgtatg gacaaataaa tatttcaaaa aatccttgat
    24181 tgatagacaa acaccccaaa ccaataaaca gatagcaaag atatcaagtc ccagtacaag
    24241 tttttcgaaa tatggaagaa gaaactgcat caactctgtc gtcatcctac ctctcctctt
    24301 ctttgttttt ctttgtcttc tatttcctga ttcaagaaat aagaaatgac tgttcgaatg
    24361 ataataataa gtgcaagctt caaaatatct gtccaagtcg gcttgataac tgactcgatg
    24421 atatcagcaa cgactagtac ttccaagctt aacaaaatat aacttgctag cagttttctt
    24481 gtatctgcat tacgagtatt acgttctgca tagtttttct tgacatgaga ccaatcaaaa
    24541 agtttgaata gaacaagaac gatcccgaca attaagatac cgatagaaca aatatttaaa
    24601 atagcaatga tccattctag aaattcaatt aaatttgagc gaaacatata cgctacctac
    24661 tttcttttaa tttgttccta ttcttttatt gtaaaagaaa gttaccttgt tcgtctattt
    24721 aaaagttgtt ctaatgataa cggttcgctt aaatttttct ttttcactct cccatttttc
    24781 tccctccatc cataaatcgt ggaagtatcc aaaacaacgt agcaagttaa aataaggctt
    24841 agtccgtcat cagcttttca aagaagcact gtctcggtgc tttttttgta cccaaatttc
    24901 taaaaataga accatacacc tcctcaaatc ttttcttctt acctacccta tttttattta
    24961 caggaaaatc agacacttct tcttttttgt caaaatttcc tttttcttct cgtcctatca
    25021 tttggcattc taataaaaac gaactatcct tggatataga aagagaaaac aaggaggcgt
    25081 ttttcatgag taaaaaatta atcaaagtcg gcatcggttt aggtttgctt gcccttggcg
    25141 ctgcatatct aggaaaaaag acaggactat tcgaagatga cagtcattta tatgatgaat
    25201 tcgaatcaat ctagcatcct atttagttga atcactacgg acatacttgg aagacattgg
    25261 aggaatcaca atgagaaaaa gtaaagcaat aatgattggt gccggtattg ccaatatggc
    25321 agcggctgtt tatttgattc aagaaggcaa atggaaaggg gatcagatca ccttttattc
    25381 attggatgat cacggttcaa atgatggtgc accgaccgac actgtagtgg atgaatattg
    25441 gaataaaaac catccattag aaaaccaaaa aggctatatt gctcgaggcg gtcgcatgct
    25501 taattaccgt acctatgtag atttgatgga tctgttaagt cgaatacctt ctgttactga
    25561 gccagggatg actgctgaag aagatacgag agattttgat gcaaaacacc gaacctttga
    25621 caaagcacgt ttgatggaag gtggcaaagg aatcattgat ggcggaaaac tgggattcaa
    25681 taataaagac cgtattcttc tgactaaact gattgctatg cctgattcag aagaagaaaa
    25741 actagacaat atcactatcg aagaatattt caaagatgat ccacactttt ttgaaacaaa
    25801 cttctggttt atgtgggaaa caacatttgc tttcagaaca cgtagttctg ctcaagaatt
    25861 gcgtcgctat atgcatcaaa tgatttatga attcactcaa atcgaacatc tagtgggcgt
    25921 caatcgaaca cgttacaatc aatacgaaag tattatgctt cctttgatcg agtacttgaa
    25981 agaacaagga tgcaaaatca ttttgaaccg ccgtgtcact gactgggaat tcaaagaaac
    26041 accgatgcaa gatgaaatca ctgtgactgg tttgaaaatt accaatacac tgactcaaga
    26101 agaagaatac gttgtggtcg atgaagatac agcagttatt ttcactaatg ggtccattac
    26161 agattcagct actttaggag attacgaaac accagctgta gaaaatatgg attatggtgc
    26221 agcttctagt ctctggaaaa aagccagtga acgtttctac aacttgggaa atcctgacaa
    26281 attctttgct gatcgagatg caagcgaatg ggtcagcttt accctgacga cgaaaaacca
    26341 tttgttgttg aatgaaatca cccgtatcac gactcaagaa ccaggaaatg ccttgaattc
    26401 atttatttca accacaccga tcacgccgtt aggccaaaaa gatgtcaata tgtctattgt
    26461 cgtgcatcat caaccgcatt ttacgtctca gaaaccaaat gaaacagtta tttggggtta
    26521 tttcctttat ccaagacgac gtggcgaatt tgtggataaa cagtatatta aaatgaatgg
    26581 aaaagaaatg ctagaagaac tgattggaca actttcaaaa gtagatcctg gaccagtgaa
    26641 tattcgtgaa aaagaaacag aaattttcga cagcgtaata aataatatcc ctgtctatat
    26701 gccttatgct tccgcgttgt tcaataatcg tgccaaaagc gatcgaccaa aagtcattcc
    26761 taaacattcg accaatctgg cctttacagg agaatttgtc gagcagcctt atcagatgat
    26821 ctttactgaa caaagtgctg tacgttctgg agaaatcgct gctttccatt ttgcgggtat
    26881 tcctatgtcc cgtcttgtca aaacaccgcg ttacgacaaa gatattccta ctctagctcg
    26941 tgccgcaaaa aaaatgtttg aataatcaag aggttgtgaa aaagctgccc tgcatcaagt
    27001 aataagaaca accaggctaa aacagcttct tatgtttttg atttggttgg acttattacc
    27061 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaagctg ccctgcatca
    27121 agtaataaga gcagccaagc taaaacagct tcttatgttt ttgacttggt tagacttatt
    27181 accgcagatg caagcttttg aacaccgttt accaagaggt tatgaaaaag gcgtttagtt
    27241 tcgagtatga agaaaaattt tgtgaaaatg gttcctcacg tttttgcata aatttgactt
    27301 aataccgaga aactgatccc ttctgtcata acctcttttt atttatgtct gtttcttttt
    27361 gaaaacaact attttttcaa cgtttactct cttgccaatc caacatcatc taacggatac
    27421 aactatttca atgattacca ttacactaaa aaatcggaaa cacacctctc cgaacacaaa
    27481 tacataagac tatagaatgt ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa
    27541 gatctccttt aaaatgaaat tatctgtagt actaataatg cagacaattt tatgaatctg
    27601 aaaggagcat ctccaatgaa agcagtcact tggcaaggaa aacagaaaat ggaaatcaga
    27661 aacgtagatg atccaaaaat attagaacca acagatgcaa tcatccgtat cacagcaaca
    27721 gccatttgcg gctccgatct gcatctttac catcatggtg aagcagtttt ggaaaaaggg
    27781 tatgttgtag gacacgaacc aatgggaatc gttgaagaag tgggatctca agttcaaaca
    27841 ttgaaaaaag ggcaacgtgt ggttatccct tttaatatta gttgtggtca ttgtcatttc
    27901 tgcctgaatc acatggaaag ccaatgtgat gaatcaaatc cagatcagtt atatggcggg
    27961 cttttcggat ttggcaagtt gaacggtaat cattggggtg gtcaagcgga atatctaaga
    28021 gttccttatg cagactctac ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa
    28081 gttttatttc tatcagatat tttgcccaca gcttattgga gcgttgaaaa cgcaggagta
    28141 aaaaaaggcg atacagttgt gattctaggt tctggtccag tcggtctatt cgctcaaaaa
    28201 ttcgctgtta tggctggagc agagcgcgta atcgcagtag atccagtaca gcaccgtcta
    28261 gataaagcgg ctaattacaa tggggttgaa acttatttct tagaagacac ggcacaagct
    28321 ggaacagaat tgtatgaact ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga
    28381 atggacggat tagagcctgt caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc
    28441 acaatctctc cattacagat ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta
    28501 actggtgttt atatgactcc agcttcttct tacccgctgc aagaattttt tatgcgggat
    28561 atcgctgtca agcatggaca ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg
    28621 attgcagaag gactattcga tcctacacaa atcattactc attcgctgcc actatcagaa
    28681 gcagcacaag catatgagat ctttgacaaa aaagaagata aaaatataaa agttgttttg
    28741 aaaccttgaa ttcagtaaaa aatacaggtg attttcttta tgcccaaaat caaacgaaat
    28801 acccatgaga tcgaaatagg aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc
    28861 ttctatttcc aaaatcgtta cacattgatc tcactggctg tcgatttatt aaccgggatt
    28921 ttctatattt ttggaagcct tgcttcctta actaaaatcc ccgatcgata tggcacctat
    28981 ttttatttgg ctggtgctat tttcttgacg attcgtccta ttctcagaat cgtaaggaac
    29041 atttttattt acgacgaaaa aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga
    29101 gaatttttca aatctcatgc ctcttttttc accctatcgt atcactttga tacagacgag
    29161 cggtcgtccc actttcttcc ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa
    29221 acgtggtatg atctgtaatt aagtaaagtt tttcgtaccc aagttgatgc atttcttttc
    29281 tgatttccgc taatatccgc ttggctatcc cctgcttacg cttttccggt tcaacaaaca
    29341 gggcacaaag atttggtgtc agatcagggc ggttatggaa gtcgttttca atgacgcccg
    29401 ctcctccgac gatggtttct ttttcatcta agaccacata ccattgagga atactttcct
    29461 tattagcgat tccagtacga atactttcct catacacaac agcaggaact ccccattttg
    29521 atgaaaacca attcgcgctt tgttttacta attctgggtg ttctcttaat ttgatccagt
    29581 tatatgtaac caatgtttaa acctccgact aaaataaaac gtttacaaaa attatacaag
    29641 tctttatgaa aattagcaat gacaacaata gtgatgtaaa aaaaaaaacg gaaaacaatc
    29701 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
    29761 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
    29821 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
    29881 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
    29941 actaacta
//
LOCUS       DACGLI010000038        28572 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.039, whole genome shotgun sequence.
ACCESSION   DACGLI010000038 DACGLI010000000
VERSION     DACGLI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.039"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(290..1087)
                     /locus_tag="IXT22_001811"
     CDS             complement(290..1087)
                     /locus_tag="IXT22_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAQ4863161.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(1084..2268)
                     /locus_tag="IXT22_001812"
     CDS             complement(1084..2268)
                     /locus_tag="IXT22_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4863162.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(2293..3540)
                     /locus_tag="IXT22_001813"
     CDS             complement(2293..3540)
                     /locus_tag="IXT22_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAQ4863163.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            3755..5500
                     /gene="dnaX"
                     /locus_tag="IXT22_001814"
     CDS             3755..5500
                     /gene="dnaX"
                     /locus_tag="IXT22_001814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAQ4863164.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            5520..5834
                     /locus_tag="IXT22_001815"
     CDS             5520..5834
                     /locus_tag="IXT22_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAQ4863165.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            5859..6455
                     /gene="recR"
                     /locus_tag="IXT22_001816"
     CDS             5859..6455
                     /gene="recR"
                     /locus_tag="IXT22_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAQ4863166.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            6519..7163
                     /locus_tag="IXT22_001817"
     CDS             6519..7163
                     /locus_tag="IXT22_001817"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAQ4863167.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            7178..7507
                     /locus_tag="IXT22_001818"
     CDS             7178..7507
                     /locus_tag="IXT22_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863168.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            7521..8459
                     /gene="holB"
                     /locus_tag="IXT22_001819"
     CDS             7521..8459
                     /gene="holB"
                     /locus_tag="IXT22_001819"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAQ4863169.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            8495..9319
                     /locus_tag="IXT22_001820"
     CDS             8495..9319
                     /locus_tag="IXT22_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAQ4863170.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            9312..9659
                     /locus_tag="IXT22_001821"
     CDS             9312..9659
                     /locus_tag="IXT22_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAQ4863171.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            9728..10600
                     /gene="rsmI"
                     /locus_tag="IXT22_001822"
     CDS             9728..10600
                     /gene="rsmI"
                     /locus_tag="IXT22_001822"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAQ4863172.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            10709..11812
                     /gene="dinB"
                     /locus_tag="IXT22_001823"
     CDS             10709..11812
                     /gene="dinB"
                     /locus_tag="IXT22_001823"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAQ4863173.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPL"
     gene            complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="IXT22_001824"
     CDS             complement(11884..12486)
                     /gene="nrdG"
                     /locus_tag="IXT22_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAQ4863174.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="IXT22_001825"
     CDS             complement(12801..14990)
                     /gene="nrdD"
                     /locus_tag="IXT22_001825"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAQ4863175.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            15316..16083
                     /locus_tag="IXT22_001826"
     CDS             15316..16083
                     /locus_tag="IXT22_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863176.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            16073..18115
                     /locus_tag="IXT22_001827"
     CDS             16073..18115
                     /locus_tag="IXT22_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4863177.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            18396..18545
                     /locus_tag="IXT22_001828"
     CDS             18396..18545
                     /locus_tag="IXT22_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAQ4863178.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            18556..20070
                     /gene="dltA"
                     /locus_tag="IXT22_001829"
     CDS             18556..20070
                     /gene="dltA"
                     /locus_tag="IXT22_001829"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAQ4863179.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            20067..21272
                     /gene="dltB"
                     /locus_tag="IXT22_001830"
     CDS             20067..21272
                     /gene="dltB"
                     /locus_tag="IXT22_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAQ4863180.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            21317..21550
                     /gene="dltC"
                     /locus_tag="IXT22_001831"
     CDS             21317..21550
                     /gene="dltC"
                     /locus_tag="IXT22_001831"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAQ4863181.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            21553..22821
                     /gene="dltD"
                     /locus_tag="IXT22_001832"
     CDS             21553..22821
                     /gene="dltD"
                     /locus_tag="IXT22_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAQ4863182.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            22962..24044
                     /locus_tag="IXT22_001833"
     CDS             22962..24044
                     /locus_tag="IXT22_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAQ4863183.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            24044..24847
                     /locus_tag="IXT22_001834"
     CDS             24044..24847
                     /locus_tag="IXT22_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4863184.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            24917..25657
                     /locus_tag="IXT22_001835"
     CDS             24917..25657
                     /locus_tag="IXT22_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4863185.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            25668..26672
                     /locus_tag="IXT22_001836"
     CDS             25668..26672
                     /locus_tag="IXT22_001836"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAQ4863186.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(26717..28561)
                     /locus_tag="IXT22_001837"
     CDS             complement(26717..28561)
                     /locus_tag="IXT22_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863187.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         9012 a         5052 c         5877 g         8631 t
ORIGIN      
        1 ctctgagtca caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac
       61 ttgtgaccga ggagttggta ggagaacacc gtttaccaag aggttgtgaa aaagctgttc
      121 tgcatcaagt aataagaaga gccaagtaaa aacagtctct tatgttttta acttggctgg
      181 acttatcacc gtagatgtaa gcttttgaac gccgtttatt tgcaacaaaa ggggctgtga
      241 cacgattttt gtcacagccc tttttttgcg aacattcatt tagcaatttt tagaaacttc
      301 tgccgccacc gccaaaagtc ccgccaccgc tagaatgggt agtacttccg ccaccgccgc
      361 ttccaggagg tgggcttttg gggattcttc ttgtcgtgac aaaagaattt gtcagacgat
      421 cggttttttc agttaatttg atactggatt tttctcggaa tggatatttg tagatgcctg
      481 atttcaattg ataacgcgaa acagtcacaa aataaaagac aagactaagg ataagagcca
      541 aaacaacagc aatgatgatt tctactgtcg tcaaaacctt atagcgtgta attttgccag
      601 tttcttcgtc tacacgataa tgtcctcctg gaactccgtc ttccacatat gttgctgatt
      661 tagacaggta agcttttgca gcattgtaat aggcagcatt tgtcatctga tcataaacat
      721 catctaagat cgaatcgatt ctgctatcag tcaaataatc gatcatatta ccagaagtcg
      781 aaatgtagat ttcacgctgt cccatatcta atagcaatac tgagccattt tgatcatttc
      841 cgactgcgtc tcttaagtaa ttatcagcaa agtctcttgg ttcttctgaa ttagatgtag
      901 tcgttacgat caagactcgt cctttgattt tttcattcag cttttctgcc tgttgttcca
      961 aagattggat ttgatctgtt gtgaataacc cagcctcatc atttaccgta gctgtatctg
     1021 catgagtagc caccggccag ccaacactta ctagcaaaag aaagaataaa aaaaattttt
     1081 tcatcatatc aagtaacctc cgatcagaaa gaggatcgct agcccagcga aaatcccaag
     1141 agcggtcagt cccaattttt tctggctgat cggcaggaca ccgctgacct ttcctgtttg
     1201 tccattcatt gcgtagtagt agactttttt acttgagtca ttgcttcgat aagtaacaag
     1261 ccataccggc agtaatacgt aattatttac ttcgtttgtg attgaagcag aagttcgcac
     1321 accggtcaat gttgtatatc catttgcggt atcttttaac agcttctctg aatagtcttt
     1381 taattcagat tgaatctgtg atttgattgc ctcatattcg atatctcttt tttctgcttg
     1441 gaacccggct aaatactggc ttttaaaatc aattgcttta tctaacggga aaggttgcac
     1501 gccttcgacc atcttttgtt gcgtattttt tgataaggca ttttttacta gttctttaaa
     1561 agaaagcttg cctgctcttg aaacagcaaa ttgcttcgtt tctgtgtatt cgatgtcacc
     1621 tatccgccat atgcggataa ctgtaccatt cgcctgcatg gcaccatcta cttcagcatc
     1681 tgtagcccaa taagggaaat acacacctgt caacttatcg atttgatcct tattgaaaaa
     1741 agctttggga acaaaccatt ttttcttggt ccaagcgaga aatctgttga ttgcttcttc
     1801 tttctcgaca gcaaaaggaa gtactttatt tggcaagaat tctccgctta aacgtcccga
     1861 tagtacgacg ggattatggc agtagtaaca ataagtcgca gcagttgtcg catcagtcac
     1921 gatctctgca ccacagttgg gacaaagaaa aagatctatc gctgcggtat tatctgcaga
     1981 ttcgtccgct gtatctgaaa aaccgcctgc ctcgtcaacc gctttgcgct cggcttcatt
     2041 catatcggca agctgttctt gggctgtaaa agtaaaatct tcggtaggtg aaggttcttc
     2101 tttgctttct tcgccagcca tacgcgcttc tttttgcttt tgctcatatt ggctgacttc
     2161 ttcttctgta tagatattca ggcagtattc gcaatgaaat ttttggtctt tgggatcaaa
     2221 agtcaacgga ccgccgcaat taggacattt atgtgtaaga acatccatca gctgcacacc
     2281 tttctaaata aattaattaa cggggattcc tttaaacggt ttaccacagt ttggacagaa
     2341 tttagggatg ccgttggaaa gatccacgat ctcattgcat tcactgcatc gcatttgtag
     2401 cttaggctga acgttttcta caggtttggc agctccgcag ttggaacaga attttccgga
     2461 attttctgtc ccgcaaactg gacatgtcca agtatccgca tttccttgtg cagtttgttg
     2521 attttgtttt tctgcttgtt gtttgatttg ttcttggtta ttttgagctg cttgagaaag
     2581 ataagaacca tttgcattca ttcccatacc tacacccata aagccggtca ttgctcctgc
     2641 ttcatttttt ccggctgctt ccataccacg tgcaatggaa ccttgcacgt atccttcacg
     2701 tacgctagga tcacctagca tcgccccttc gttacgcata ttgatcagtt tcacagaatc
     2761 atcggtgtaa gaaatgctgg ctacagccac agaaacaatc tccatcccac gtaattcacg
     2821 ccaagaatca tccaatgcag tatccatgta tttgcttaat tccaaactct tagatggtac
     2881 ataagaaatc cgttgaccat ctgcagacat ctgattgatt gctgattgta gcgctgttag
     2941 gaattcagct aaatactgct cattgatatc attgatttcc acttgtgttt tgtttttagg
     3001 gattgcgttt gtataaaata aaatcgggtc aacgacatga atagaataag tgccatgtgc
     3061 ccgtaagaat aattctgcgt tatagaaatt gtcaaagtag ttcaacggcg cgcttgtacc
     3121 gaatttgatt ccctttattt cttggagatt gatataaaaa acttgttgtt tctgcggtgt
     3181 gacgccgcca aatttgaatc ggtcaaaagt ttcagcaatt gcttctttca gtgttccatt
     3241 gaacatggaa ggagctgcgt catttttaat ggtgtaataa ccttcctcag cggtataatc
     3301 gatgattttt ccaccatcga ccaaaagcat catcatgttt ggatagacat ggacgactgt
     3361 tccgtctgtt aaaacatctt ctgttccttt acgattggag ccacgtttgt catctttgcg
     3421 gactttgaca ccttttgtca tgaccgttgt atcactcata ttgtctggtt cgatgacttc
     3481 tagccattga tctgccagac cgccgccaac catacttgtt gctgctttga taagacccat
     3541 aaaaaattcc tcctctgatt cagctagtgc caaacaatta ttgtttattt attataccat
     3601 aggaagatgt gaaacttctc ggactagaga cggaattgaa atggaaaatt gcgtattgtt
     3661 taaatacctg aaaaagccga gaaggatagt agttttttta cctaatatca cgtataataa
     3721 gagatagtga attttttaaa aaagggggat ccttatggca tatcaagcac tttatcgagt
     3781 ctggcgttcg cagcgtttcg aagacatcgt tggacaaaaa gctgtgacac agacactaaa
     3841 aaatgctatt gtttcccaca aaacctcaca tgcctacttg tttacaggac ccagaggaac
     3901 cggaaagacg agtgcagcaa agattttcgc aaaagcaatc aactgtccga acagtaaaga
     3961 cggtgagcca tgcaacgaat gcgaaatgtg tcgatcaatt actgccggta cgcaagaaga
     4021 tgtgatcgaa atcgatgctg ccagcaataa cggagtcgaa gaaatccgat ttatccgtga
     4081 tcgggcaaat tatgcgccta caaaggcagc gtacaaagtg tacattattg atgaggtaca
     4141 tatgctttca acaggagctt tcaatgcctt gttgaaaaca ttggaagagc caaaagaaag
     4201 tgtcatattc atcttagcaa cgaccgaacc tcacaaaata ccagctacga tcatttcacg
     4261 gactcagcga tttgatttta aacggatcaa tacggcagat attgtcgaac atcttgaatt
     4321 tatcttgaaa gaatcgacta tcagctatga accagctgca ttgaatgtga ttgcccgttc
     4381 tgcagaaggc gggatgcggg atgcattgag tattcttgat caggcaatct cgtttagtga
     4441 aggaacaatt actttagatg atgccatgca agtgacaggt agcttaactg acgaaatgat
     4501 ggacagttac ttgagtgctt gcgtgaaaaa agaagtacca gaagcattgg aaacattgaa
     4561 ccaaattctc gcagccggca aagaatcacg tcgctttcta gaggatatgt tacaatactg
     4621 ccgtgacttg ctgatgtatc agcaagcacc taacctagtt gaggaacaat cgagtacgat
     4681 cagaagtaca tttacagaat tggcacaaac tgtttcagcg gatcagctgt tttcaatgat
     4741 aaagattttg agcgatactc aaaatgaaat tcgttttacc aatagtgccg ctatttattt
     4801 ggaagtcgct acagtcaaac ttgcacagct accgtctgct tctgttcctt cagcagatgt
     4861 agcatttgca gatgatcaga tagtaaaaca gctacaacaa gagattaagg aactaagaaa
     4921 cgaaatcaag gaactacgca gtaatacagg aattgagaat acaaaagtac agccggtaca
     4981 gcaaacaaat cataaaaaac agacaagtac ctatcgtgta ccgacggaac gagtatataa
     5041 agttctgcgg gaagcgacaa gacagcatct gaaccaagta aaagaagtat gggaagactt
     5101 gctgatgagt ctatctgtca ctcagcgagc aatgcttaaa gcaagcgaac cagttgcagc
     5161 tggacctaca ggactagtga ttgcgtttga ttatgagatt gtttgtcaaa gagcagcaaa
     5221 tgacgaagaa ttgcagcttt cggtacacaa caacttaagc cgaatgatca aagattatgc
     5281 gcctgatcct gtttatatta caagagaaag ctggccagaa cttcgaagaa attatttgac
     5341 gcaggcacaa gaagagggaa cagaaaactc ttttgcttct gaagactcag aaggagaaat
     5401 cgagttgctt cctcaagaac aagaagtacc agaagaaaca cttgtagtaa aagcagagga
     5461 actgtttggc tccgaagctg ttacagtggt agatgattaa taaaaaggag tagataatta
     5521 tgatgcgtgg aatgggcaat atgcaaggca tgatgaaaca agtacaaaaa atgcaaaaag
     5581 aaatggcaga agcacaagag ctgctaaata aaacagagtt tacaggtaaa gccaccaatg
     5641 aattggtcaa agcggttttt acaggcgatc gtcgcatgaa agatatccaa atcaatgaag
     5701 aagtcgttga tcctgatgat atcgagatgc ttcaggatct tgtcgtaatg gcagtcaatg
     5761 atgcgatcgc acaaattgat gtggaaactg agaaaaaatt agggaaatac gcaaaaggtt
     5821 tgccaggatt ttagttttaa actgaaggag taatgaatat gcaatatcca gaaccaattg
     5881 cgaaactgat cgacagctac atgaaacttc caggaatcgg tcagaaaaca gcgacaagac
     5941 tcgcctttta tacgatcgat atgaaagatg aagtagtaaa tgaatttgct aaatctttgt
     6001 taagtgtaaa acgcgatttg catttttgta gtatctgcgg aaacatcaca gaagaagatc
     6061 cctgcgaaat atgtagaaat ccttcacgtg atcgaagcgt tatcctagtg gtcgaagagc
     6121 cgaaagatgt aatggcaatg gaaaaaatgc gagaatatca cggactttat catgttctcc
     6181 atggtgtgtt atcaccgatg gaagggacag gtccagaaga catcaatatt tcttctctgt
     6241 tgcagcggct gcatgatgca gatgtaaaag aagtgattat cgcaacaaat gcaacaacag
     6301 agggagaagc aacagctatg tatctctcac gtctgatcaa acccgcaggt atcaaagtga
     6361 ctcgtctagc acatggtctg tctgtaggct ctgatatcga gtatgcagat gaagttactt
     6421 tattgaaagc tgtcgaagga agacgtgagt tataaatttc taattaagtg ttttttcaga
     6481 tacaatataa aagcagcaca agagatgggg gcaacaatgt gaacggacta tttattacaa
     6541 tcgaggggcc tgatggtgca ggaaaaacca gcatcttgaa tgaactttac cctcttttga
     6601 aagaagtagc aaaaacagaa atcattcaaa caagagaacc aggaggcatt ccgattgctg
     6661 aagagatccg agcagtgatc cttgatccaa aaaatgatcg gatggatgaa cgtacggaag
     6721 cactgcttta tgcagcagca agaagacaac atctagtcga aaaggttctg cctgctctgg
     6781 caaaagggaa aatcgtttta tgcgatagat ttgtcgacag ttctcttgct tatcaaggtg
     6841 caggccgacg catcggcgtt accgagattg ctcggttgaa tgagtttgct acagaaggta
     6901 ctacgccgga ttttaccctt tatcttgacg tagattcaga caccggatta agaagaatca
     6961 agaaaaacag acaaaatcaa atcgaccgtt tagattcgga aggtttggaa ttccaccagc
     7021 gtgtacgtca tgcttactta aagctggcag aagagaatcc ggaaagaatc cacaaagttg
     7081 atgcaagaaa aagctttgaa gaagtgctgc aaacaagtta tcatacaatt attgaacagt
     7141 atccgcaatt ttttgaaaac taggaaggtg aacgtttatg aaaattattt tagcgattat
     7201 ccaagacaaa gacagcaacc gtttatcaaa tgaattgatt gatgcaaata tccgtgccac
     7261 aaaactatca tcgacaggcg gcttccttaa ggctggaaac agtacgttta tcgtgggtat
     7321 tgaagatgac cgtgtagaag aagcattgga aatcatcaaa aaaacgtgtg aatcaagaaa
     7381 gcaatttgta tctacacctg ttacactgga tatttcgatg gatgggggcg tcccttatcc
     7441 agtagaagta gaagtaggcg gtgccacagt cttcgtctta cctgttgaag gattccatca
     7501 attttaggag gagctgagct atgaatcaag aaataaactt ggctcaaatg caaccgatcg
     7561 tgtatcagca gcttcaacgg agttttgagc atgggcgtat cgctcatgct tatctttttg
     7621 aaggggagaa aggaacagga aaacatgaag taggtatatg gcttgcacag cacctgttct
     7681 gtacccaaat gaaagacaat ctgccttgtg gaaaatgcaa caattgtcag cggatcgaaa
     7741 agaaagaaca tccagatgtt ttggttattg aaccggaagg acaaaccatc aaagtcgatc
     7801 agatcagacg tttgcagacg gaattcagtc gcagcggtta cgaatcaaga aaaaaagttt
     7861 ttttgatcaa agaagctgaa aaaatgaata gcagtgcggc aaacagtttg ttgaaattct
     7921 tggaagagcc ccctggagat tttttagcgg tgttagaaac agatgcagta ggaagaattc
     7981 tccctactat tcaatctcgt tgtcaagttc tgcattttca agaactttcg aaagaagcac
     8041 tgatccatcg attgcaagaa gagcagattc cattggaaaa agcaaaactt ttggctttct
     8101 taacaaacag tttaggaaaa gcagttgaaa tctctcaaga tgaatggttt aatgatgcta
     8161 aggacttgat ttatcaatgg ttcgtttact tgcaaaagca agatactcaa gcctttatct
     8221 atgtccaaaa aaaattggta aaatcattta aagaaaaaac acaacagttt acaggattat
     8281 ctgtcttgat gttttattat caggaagcac agcgtcaagc agtagcaaac ggcgaatatg
     8341 gcaaagtgaa acagataaac cagataattg aacggatatt gatcgcagag cagaaactac
     8401 gcagcaatgt cagttttcag gctgttgcgg aacagttcgt tttgcatacg attttttagc
     8461 ttgccgcaaa ggatgatgat caaggaggat ggaaatggta gaagtagtag gtgtccgata
     8521 tagagatgca ggtcatatct attattttgc accaggagac tctgaatatg tttatagtga
     8581 caaggtatta gtcgaatctc agcaatcctt acatattgct actgttgtcc ttcctaaaaa
     8641 agagattgat cccaatgacc ttcctgaagc tatccgtccg atcttgcata aagcgtcaca
     8701 agctgaatta gaaaaagaca aaaaaaacaa aaaagatgct tatgatgcat tgaaaatcgc
     8761 aaaagaaaaa gtgcagttgc gtgagttgga aatgaaaatg gtcaaagccg aatacacatt
     8821 tgatcgaaat aaattgattt tttctttcac agcggacggg cgaattgact ttagagaatt
     8881 ggtaaaagat ctggccgctg tatttcgtac tcgtattgag cttcgacaaa ttggtgtccg
     8941 cgatgaagca aagataatag gcggaattgg tccatgtggg cgtccattat gctgttcttc
     9001 ttttttaggc gatttcgtgc ctgtatcaat caaaatggca aaagatcaaa gtttatcttt
     9061 gaatccaaca aaaatttccg gtttatgcgg acgcttgatg tgctgtctgc aatatgagag
     9121 cgaagaatac gagacagcga aaaaagaact ccctgacttt ggaaaagtaa ttgctacacc
     9181 tgatggtaaa gggaaagtcg tagggttgaa tctgcttagc cgtatcgtta gtattcggct
     9241 gactggacgg gaaaatcctg tcgaatatga atgggatgaa ttgaaagaat ttatccaagt
     9301 aggtgagatg aatggataag agatcattat acgacggatt gaatcaatta gaatcagagt
     9361 tgagaaatac attaacagaa cttgttgaaa tgaagcatgc tttgcatgag atcgtagaaa
     9421 aaaatacaac tttggagatg gaaaatcaac gtctgcggga acacctgcgg gaattgaacc
     9481 aagttgcaca agctccagct gaaaatgtga agcaggaact ttctaagtct cgtatgaatc
     9541 ttgaaaaaat ttatgaagaa ggattccatg tctgctacga tttatatgga tcaagaaggg
     9601 acaatgacga gccttgtgcg ttttgtctag aagtgatcta tcgcgaaagc ggtcgatgac
     9661 caataacaag aggagactgg agcggagaaa tactgctcca gtctttttat taaggagatt
     9721 gtgacagatg tataatcaaa aaagtttcaa gggaaatccg gtatatgggg atttatatct
     9781 tgtaccgacg ccaattggaa atttagaaga tatgagctac agaagtgttc gtatgctgca
     9841 agaatccgat cttatcgcaa gtgaggatac gcgtaataca caaaagttat tgaatcattt
     9901 tgaaatccat acaccccaaa aaagtttaca tgaacataat tataaagaac gtgtccctca
     9961 attgattgct ttgttaaaag aaggaaaaac gattgctcaa gtcagtgacg caggaatgcc
    10021 ttccatcagc gatcctggac atgagctagt tttagcctgc ataaaagaag ggatttctgt
    10081 gatctctatc ccaggaccta cagctgggat gacggctttg attgcttcag ggctagtgcc
    10141 tcaaccattt ttattttatg gcttccttcc acgtaagaaa aaagaacaga aagaaacatt
    10201 gaaaaagcta aaagaacaga cagttacgct gattttttat gagtcacctt atcggatcac
    10261 tgctacattg acgaatttct tagaaatttt tggaaatcgc caagtcgttt tgtgtcggga
    10321 attgacaaag gtccatgaag aataccttag aggaagtacg gaagagctac tcgcttatat
    10381 cgaagaacat ccagtaaagg gtgaatgttg tctgcttgta gaagggaatt tgttcgaaat
    10441 gccagtgacg gaagttgatg aagagttggg aacgttaaag gaacaagtag aagcaaagat
    10501 cgcttcaggc gaaaaaccaa atgctgctat caaagcagta gcgctgaaaa atgggctgaa
    10561 aaaacaagaa gtctaccgtc agtaccatga attagactga gatagtataa gttgtctata
    10621 atgaaagact aatgaggaaa tcagctacta acttttcaaa tctcttgaac gcgaacgaat
    10681 gttcttgtat aatgaataag aggtgaggat gatggagctg caatttcctt tacataatga
    10741 tacatcaaga aaaatcattc atattgatat ggatgctttt ttcgcttcgg ttgaagaacg
    10801 agatcatcct gagtttcgcg gacatccatt agtaattgcc agacacccca gtgacactgg
    10861 tgggcgtgga gtagtgacta cagcaaatta tgaagcaaga aaattcggaa ttcattcagc
    10921 aatgagtgca caaaaagcgt atgagctttg tccgcaagcc atctttaagc ctggcgacca
    10981 tcataaatac agcgatattt ccaaacaagt acgggaagta ttctatcgtt atacagatat
    11041 tgtggaacca gttagtatcg atgaagcgta tcttgatgtg accgaaaata aaatcaattg
    11101 caagtcagcc atcaaaatcg cccgaatgat ccaagcagat atttgggaga gtgtccagct
    11161 aacatgttct gcgggagtaa gttacaataa gtttttggcc aaattagcat cagactatca
    11221 aaaacctaga ggaatcacgg tagttgcccc tcaagacgct gtgccatttt taaaagcttt
    11281 gccaattgaa aaatttcatg gggtagggaa gaaaactgta cctagaatgc atgagctagg
    11341 gatttataca ggaaaagacc tatatgaatg cacagaaatg atgttgattc gaaattttgg
    11401 aaaaatgggc tattctcttt atcgtaaagt cagaggaatc catgattctc cagtaaacgt
    11461 tacaagagag cgaaaatctg tgggaaaaga gcatacttat gggcagccgt tgcaaacgga
    11521 agaagcagtg ctgactcagt tgcgccaact agctgaaaaa gtagaagaag cactgagaag
    11581 agtccaaaaa catgggaaaa cagtagtttt gaaggtcagg tacacggact attctactgt
    11641 gaccaaaaga gtgacattgc cagaatatat ctataaaaaa gaagcactct tttatcaagc
    11701 aagccttata tgggaggaaa tcttgggagt agaaaaagga atccgattgt tagggattac
    11761 tttgacgaat ctggacccga tgacttatga aaacatcgtc cttccattat gagaaaatca
    11821 agaaatataa aaacagcttt gagagttgaa accggaaatc cgttttctct cccaaagctg
    11881 tttttatatc aagtcttgct ttttgatttg ttcataggtt tctgttgcat ccgtacattt
    11941 ttcccaaatc acaacttgat tggattctaa agatttttgg acgtcaatga tccgctggtt
    12001 gctacttccg cgaaattgta gttttaggtc acgtttgctt aattcaaagc gtccgtcaac
    12061 aaggatatcg atttgcgaaa ggagttctaa tttatcttct gaatcttgta gcaattcatc
    12121 aaaggtatag cctgtccatg accagatatc ttttgtcgta ccgaactctt ttcggatacg
    12181 tcgtacgact tgcagacaaa catctgtatt caaaaaaggt tcgccaccaa gtaaagttaa
    12241 tccttgcacg taatcgttgc gcaagtcagc gatgatttgt tcttctaatt caggtgtgaa
    12301 tggtttgcca tatcggaaat tttgtgcagc tttgttgaag cagccttcgc aggcaaataa
    12361 gcagccacta acgtaaagac tgttgcggac accttcacca tcgacaaaat taaacggttt
    12421 gtagtcagca atatagtttt ggctgtagtc ttttgctaac cattcttttg gttttggatt
    12481 tctcataaaa aaacttcttt catttaaggt tcaaagatat agctattgaa gataaaatct
    12541 actcgaccac ataaataaga acaaactgac ctaaatccat tgttcaagaa agcttgttct
    12601 tattttgata gagggcgttc aaagatacaa agccatcgaa agagggtggt gaaaaaagac
    12661 ttgtcatagc ctcttattct gaataaacgg tgttcaaaag cttgcatctg cagtaataag
    12721 cccaactaaa cgaaaaatat gaggaactat ttttgtttag ctattcttat tacttgatgc
    12781 aggacagctt tttcacaacc tcatttcatg tgtttcacac gtgaggaaat ttctttatgg
    12841 cggccatgta ccatcggacg agcttgcgga tttcctaaat agccacaagt acgtttgact
    12901 acatcacatg tttttggatc atgatttcca cattctggac attcgaaccc tcgttctgtc
    12961 ggtttgaaat caccttcgaa accacattga tagcaatgat cgattggcgt attcgtacca
    13021 agatacccga ttttgtcata tgcaaaatcc catacagctt ctaaagcttt cggattttgt
    13081 tggagcatag ggtattcaca gtagtggatg aatccacctg aacaatattt tggataatcc
    13141 ttctcaaatt ccaatttttc aaatggcgtt gggtttttac gcacatcata gtggaaactg
    13201 tttgtataat attctttatc tgtgatattt tcgatgatgc cgaatttttc tgtatccaaa
    13261 cggcagaaac ggtcagttag actttcactt ggagttgaat agacactgaa atgataacca
    13321 tattcatccc cccatgcatc tgcattagct tttaattctt tgacgatatc aagtgtgaaa
    13381 gcttttgctt ctgggtttgt ttcccattcg ccaccgaaga aagctgaagc aacttcatac
    13441 aatccaatgt agcctaacga tacagtagct cgacggtttt tgaataattc attgacagaa
    13501 tcggtacgtg aaagacgttt cccgaaagca ccatacatat ataaaattgg cgcatttgct
    13561 ggaatggctt ctttacaacg ttctacacga tagagaagcg catctttcat gatttctaag
    13621 cggtcagaca gtaactgcca gaatttattc tgatctcctt ttgattcgat cgcgattctt
    13681 ggcaaattca atgtaacaac acctaaattc attcgtccga catttacttc ttgaccattt
    13741 tcgtctttcc acccttgcaa gaatgaacga cagcccatag gtactttgaa acttccagtt
    13801 aattcaacga ttttatcgta attcagaata tcaggataca ttcttttcgt tgcacattcc
    13861 aatgctagtt gtttgatgtc gtaattagga tcttcagggt ttaagttcac accttttttc
    13921 aaagtgaaga tcagtttagg gaagatagct gtccgctttt cactccctaa tccattgatt
    13981 cgaatctgta aaattgcttt ttgaatttct ctttcaaacc agttttctcc tagtccaaat
    14041 cctaatgaag tgaaaggagt ttgtccattt gaagtaaata aggtattgat ttcatattcc
    14101 aaactttgca tagcatcgaa gatatctttt ttggtttttg cttttgcata ttctttttgg
    14161 cgttctggcg aatcgatcca ttcttccgcg tcttttagat gttttttata gttcaattct
    14221 gcaaaaggag caagcaattc atctgttcgg tcggcagaac agccaccata ttgacttgac
    14281 gctacattgg caataatctg tgagatttgt gctgtggcgg tctggataga ttttggcgat
    14341 tcgacttcgg cattgccgat tttgaaccca ttgttcagca tgcctttgaa atcaatcaag
    14401 cagcaattcg tcatcggtgt ataaggatga taatccaaat catggtaatg gatatcgcct
    14461 ttttgatgcg catttgctat atgtggtggc aacattttca gtccgattga ttttccaacg
    14521 atcccggctg tcagatctcg ctgtgtattg aaaacattac tgtctttatt tgcgttttcg
    14581 ttcacgacag tttggtcctt gttgattagc ttttcaatcg aaaagttgat atctgttgct
    14641 ttactgcgag caaaatctcg tttggtacga taattgatgt actcttctgc taattcatat
    14701 tcgttttttt ctagtaatat atgttccacg atgttttgaa tctcatagat tttgacattt
    14761 tcagcaaacc ggcttttgat ttcttggaca accaagtctg caatcatttg aattttttca
    14821 taagtaagtg gtgataatga gccgtgaatt ttcttttctg ctttgatcag tgcttcattg
    14881 atcttttgtt catcgaaatc aacatggcgg ccatcgcgtt tgatgacttt catctgggat
    14941 gtctctggct gctgagtaac gacagttttt tcttcataat ttactttcat tatcttcaac
    15001 tcctgctaaa ttgttcttgt ctatcataaa acaaaatcgg ggaaggagca actaaatatc
    15061 ggctatatat agtattcaat gtgctgtata attggatttc tatactatat gtagtgtata
    15121 ttttattgtg aaaaaaggtg aaaacttgta gctggtggat ttgttttttg catatttaat
    15181 tttgctgaat aaaataattg aataaaattt tttattcagt ccaagtaaaa gtgacaaaaa
    15241 cataagagca aattattcgt agatatgcta ctatgcaaat aaatagaaat gaaaaatgaa
    15301 agaggaggag aagaattgga aaagatgatc gaagtgaaac atctaagtaa aagctacggc
    15361 agcaaacttt ctcccgtcaa agccttagat aatatctcat tcacagtaga agaaggcgag
    15421 tttgttggga ttatgggccc aagtggtgca ggaaagacaa cgctgatgaa tatcttgtcc
    15481 acgatcaatt tgcctacgat gggcagtgtc tcgatccaag gaaaagaaat cacaaaaatg
    15541 aaaaacagtg agctcagtga ctttcgtcga aaaaaactag gattcatttt tcaagagttc
    15601 aatttgatcg ataccctaaa tgcaaaagac aatatcctat tgcccctagc agttgaacgg
    15661 atgactaaag aggaaatgga aaagagagta agacatgtag ctcaattgtt gaatatagaa
    15721 gaactgctca aacggtatcc cgatgaactt tctgtcggac agagacaacg aattgcagct
    15781 gctagagcac ttgttgttca gccacaagtg atttttgcag atgaaccaac tggctctttg
    15841 gactcgaagt cggctacaga attgttgaac tacttgaaga ccatgaatca aaaagaaaaa
    15901 gcaacgatac tgttagtcac ccatgatcca tatacagcaa gctactgcga tagaatttta
    15961 tttattaaag atggtgtgat tttttctgaa gttgtcagaa gagggacaag aagagagttc
    16021 tttgagaaag taatagacat gcaggcgacg attggcggag gaggaaaaat gaatgctgta
    16081 taaactagcc gttaaaagtt tttttcggca gtcacgaggc tatcttgttt attttttcag
    16141 tttgacttta tccgtaatga tctattattc cttcagcgca atgacctacg atcaatcttt
    16201 agtcagaaga gcaagtcaag atacttcgat agatggtgga ttgagttttg gtggatttat
    16261 cattactgtt gttttgcttt ttttcgtatt cagtgccaac cgatttttct tgaatagaag
    16321 gcaaaaggaa ataggcatct atcagctttt tggtatgaat aaactgcaga tatcaggtat
    16381 atatgtgtta gaaatcatga taattggatt gttcgcctgt atttctggga tattactcgg
    16441 tattattttt tccaaactct tttcaatgat tttggttcga atgatggata tggatcttac
    16501 tagtccattt tttatctcca ttccatcagt agtagatact ttatttgctt ttttcatcat
    16561 ccttttagca gtatctgtat attcaatatg gaaaatatgg cgctatccaa tgattcgaag
    16621 ttttggagaa aaagaacaag cagatagttc aacaatgcgc ttcaggacaa ggcaccgatt
    16681 actcgcagtc atcgggttac tacttttaac gagcggatat tttggagcta gtcattttag
    16741 ggaaatcact tcatggatga tcagttatca ttatcttgat acattagttt tcttttttcc
    16801 ttttttaatt tttttcgttt gtgtggtcgg tacttatttg tttttctgtt atacatttcg
    16861 gttatttttg atcatattga gtaaatggaa gatttattac tatggtatca attttttgat
    16921 aatgggtaac acgcaagttc atttgctcaa aagttggcgt acaaattctc tgattacagt
    16981 cattctcgga atttctttaa tgacaattgg cggcacggct agtatctcta ctattttatc
    17041 ctaccaggag aaagtttcct ccccgatgga ctatcagttt gatgttgaga cagagaaaaa
    17101 aatcaagccg attctagcag aggaagggca gaagataact aaagaaatca ccttgcatta
    17161 taaagtcatt gggagtatct atagtcaaaa tctcgaagaa cctatgtttc aaactgctaa
    17221 tctgatcacg gaaacacaat atcaagcctt cagaaaagtt aatccagatt tgccgaacat
    17281 ttctttgaaa tcacctggtc atactgtttt gcttgatcaa atgcaaactc tttttcggaa
    17341 tatttcatta tatggatcta gtattggact gccagataat caagaattga agattcaaca
    17401 aatgcttcca agtgtattag gtgacgaaac aatggtatat ctaagtcctg tactgattgt
    17461 agatgatacc gtttttgaaa aagcaaaagg tgtggattat caagtagtca atgtagatgt
    17521 atcaggtgga aataatgaaa aaatagatga acgactgagc aatgacctgt cgataaagtg
    17581 gctcaatgct gtttattatt cttatgatat cgtaaatgga agtctacaag gagaaattag
    17641 cacaaagaaa cttccggatg accaaatgaa ggaagcacaa tttagccaag aaagctctcg
    17701 tttgaatttc tcttccagct attcgaaatt gcgtgcagtt aatcggcgaa tcggtatcaa
    17761 tatttttgtc acactatttg tcgggatgat cgtgattatt gctactggta gtattttgac
    17821 agtccggcaa ttagcagaag cagaggaaga aaaagaaaat tatcacctat tgactaagct
    17881 ggggattcca caaagaagga tcagacggat gatcttcgag caaaacgcac ttaccttctt
    17941 tccacccatg atattaggga tcactcacgc agtatttgca atcaatgtct tcactcagta
    18001 tataaaaact gccgattact ggttggctta tcttgtgagt ggcttattga tccttatcta
    18061 tcttttgctt tatgtcatta cgagtcagtt atattgtcgg attatcgagg aatgatatac
    18121 ggaataagac aagataataa atagaactaa attttgaata ccatttattt ggaataagag
    18181 gttgtgacac gatttttgtc acaacctctt tattttttat attttttaaa agtacgagaa
    18241 attataaaga aaaaagcagt gatttgatgt gctattttta taaaagctat gtgacaaaac
    18301 tgttagtaaa aaaacggttt ctgtaagcta gacacatgtt tctttttgtc aaaattagtt
    18361 acactttgtg tgaggttata tgaggaggga atccaatgaa caaatggcgt tctaatccaa
    18421 aattgaatta ttggggaaaa ttcatcattc gaacaatttt ttatagtgca gtactgctgt
    18481 tcctgattta tctgtatcac tataaaaata ttcaaggagg aacttttatc tataacgaat
    18541 tttaggagga agagtatgga aatcaaaacg attattgaag caatcgatga ttggggaata
    18601 aatgaacctg atcgagttgc ttatcaggcg gatgagacgc atacttttgg tgaattgaaa
    18661 caagcatcag acgcacttgc ttattattta gaaaaaaagg tagaaggcga tggaccaatt
    18721 gtcgtttttg gcaatttgga gtttgaaatg attgtctcat ttctaggggt tgtcaaatct
    18781 ggccatgcct atttgccgat tgaagagcat acacccaagg agcgtatcct atcgatcttt
    18841 cgggtggcta aaccatctat ggtcatcagt atcggggact ggatagaaga tattccttcg
    18901 gttcctgtca taacaaaaaa agaatttcaa gaaatcaaga agataccagt aggattttat
    18961 cccagaaata gcgtaaaagg tacagaaaat ttttatatta tttttacttc tggtactact
    19021 ggagaaccaa aaggcgtaca aatcagtcat gataatctag tcagctttgt tcaatggacg
    19081 atggaagact ttgggatcaa gcctggtatg catttcttag cccaagcgcc attttctttt
    19141 gatttatcgg tattttctat ttatcctgca ttagtttctg gcggaatgct gaagccgtta
    19201 aataaagcag ttgttcaaga ctttcgtcaa ttattcgcga cattgccagc cttgaagttg
    19261 aatgtgtggg tttctactcc atcatttatg gatatttgct tgatggaacc tacattcaat
    19321 ggagaaaatg tgccggaatt ggacatgttt ttattttgcg gagaagaatt gacgaaaaaa
    19381 actgcagaaa gtctacttga tcgattccca aatgcacgga tatataatac ttacggtcca
    19441 acagaagcaa ctgtagctat ttcaagtatt cagattgacc agcatgtact agatagttat
    19501 gaccgactac cgattggcta cgtaaaaaaa gacacgaaag tttctattgt ccaagaaggt
    19561 aaacctgttt caaaaggaga aacgggtgaa atcattattg caggaccaag cgtatcaaaa
    19621 ggttacctga acaatcccga aaagacagct gctgcgttct tttgtcaaaa tgacttagca
    19681 agttaccata caggggatgc aggtagacta gatgaatatg ggcttttatt ttatgaagga
    19741 cgtatggatc agcaggtcaa attacatgga taccggattg aactcgggga tatcgaacat
    19801 tatctgctcc aagacaaccg aatcaaacaa gctgtcgtcg taccaaaata ccaaggaaca
    19861 aaagtacagc agctggttgc ttttgtcgta ttagaaaaca aaacgaaaca gccggatttt
    19921 cagttgacta aatctatcaa agaacaatta ctagaagttg taatggatta tatgattcct
    19981 cagaagttcc attatgtcga tctgctgcct cagacagtta atggaaaaat cgatcgaaaa
    20041 aaattaacag ctgaggtgaa tcctgaatga tgttacctca tatgatccct tatgcagagc
    20101 cgttttattt ttttctttta gccattgcgc ttgtaccgat cgttctatct ttattgatat
    20161 gggaaaaaag attaccagtt tatcaatcag cagtgacact tttcttttta tttgtcagct
    20221 ttggaggtaa ttattggcaa cagggagcgg cgctgattgg gtatgttttg tggcagacga
    20281 tacttgtatg gggctatttt gtttatcggc aaaggaaaaa tcagacagga tggttttttg
    20341 ccgccgttat tttagcgata attccactgt ttttaacgaa agtgactcct ttttttgaac
    20401 atggaaaagc atcgttactt ggttttttag gaatctctta tttaaccttt aaatctgtac
    20461 aaatgatcat ggaaataaga gatggcatga tcaaaacata taagccattt cgttatatcc
    20521 agtttctgct gttctttcca acaatctctt ctggaccaat cgatcgctat aggagatttg
    20581 aaaaagatca gctccatccg cctgttcgtg ataaatatgt tgatcttttg ggaaaaggcg
    20641 tccaaaatat ttttgtcggt tttttatata aattcattat cggttattat tttggtcaag
    20701 tactgcttcc tgtagtggga cgcattgcct tacagcatgg tggtatttca tgggcattag
    20761 taggttatat gtacgtgtac agtatgtatt tgttttttga ttttgctggc tatagcttat
    20821 ttgcagtcgg tacaagctac atgatgggat atcagacacc aatcaatttc aataaacctt
    20881 ttttatcatg gaatatcaaa gaattctgga atcgttggca tatgacgctg tccttttggt
    20941 tccgtgatta tgtatatatg cgattgatgt tcttcatgat gaagaaaaaa ttttttaaaa
    21001 gcaagatcgt aatgtcaaat atcggttatt ttgctttgtt tcttctaatg ggtatatggc
    21061 atggattgac gtggtactac atcgtatatg gactgtatca tgcttgtctg atctgtctga
    21121 cagatgcatg gatccgattt aagaagaagc ataaagagca gttgccttct aacaaattta
    21181 cgcatggctt agccgtattt ttgacatttc aagcagtatg ttttagcttc ctgatttttt
    21241 caggattttt agataaactt ttttttagct aacgaatagt gacatattaa tttatataac
    21301 aaaggagaaa aggaaaatgg aagaacaaat tttatcaatc ttagaagaaa taacaggaac
    21361 agatgaagta agaaaaaatc gtgatattga tctatttgat gaagggttgc ttgattcttt
    21421 agcatctgtt caattattag tcgagctaga cggagagctg gatatccaag tccctgtatc
    21481 tgaattcgag cgagaggatt ggagcacacc gaataaaatc attcaacaag caactgcatt
    21541 gaagggttga gtatgaaaaa gaaacttttt gctattttcg gcccggttgt tttagctgtt
    21601 ggcttactgt ttgtgttttt tacctcctcc tatcaagtag atatctctaa tccagaaacg
    21661 attagacgtg cctcttcttc catgtcagtg aacgtgttga aaggagatgc gataaaaaat
    21721 tatgcattat ctgaaaaaca atatattcct ttttttggct caagtgaatt aagcagaatc
    21781 agtccatttc atccgtctgt tctggcagaa aaataccagc gaaactatcg tccatttttg
    21841 ctgggagcac ccgggacaca atcgttaagc caatatatga tgatgcgttc tgcaggagat
    21901 gctatgaaaa acaagaaagt cgtctttatt atttctcctc agtggttcgt taaaaatggt
    21961 gtaaaaactg attactttaa tacgtattat tctgaacttc aaacatacga ctggttgttt
    22021 tcaatgaaga aagtaacgcc tgctgatcgc tatttagcta gaagattatt aactttctca
    22081 aaagtaaaag agaatgatac gttgacggcg attctgcaaa cgatcaaaaa agggaagcta
    22141 cctttacctg aatctttgaa tcagctgcgc agccaatgga acatgctgaa gagagaggat
    22201 gaagtattca gcaatattgg gttgaaagat cgacagcaaa aaatcgatca tgagtcaaaa
    22261 cgattaccaa aacaatacca agaaacagaa ttatccattt tagcaaatca aattggagaa
    22321 cgagaaacga cgaataatcc attcgggttg aaaaacgatt tttatacgca tcgtatccga
    22381 gcccacgagc cagagctcaa acagtcacaa aaaaattggg attatcgttt ttcgccagaa
    22441 ttttctgatt ttcagctggt cttggatcaa ttagcaaaaa accataacga agtattgttc
    22501 atcatcccac cggttaacga gaaatggagc gattataccg gactatctca agaaatgtta
    22561 caaggatttg ccaaaaagat caaatttcaa ttaaatagcc aaggattcaa tcgaatagct
    22621 gattttgtca atcaagcggg taccaactat tttatggaag acacgatcca tctaggctgg
    22681 aaaggctggt tggctgcaga tcaacagatc agaccgtttt tagaagaaaa tcatattact
    22741 gctagtaagt atcatcttga cgatgctttt tttagcaaat cttggcaaca tcaaatacca
    22801 gataaactac aattaaaata aagaaaacag gcgagtgttg ctcgcttgtt ttctttattt
    22861 ttgaatattc tgaataaaag ataaaaatac caagtttgcc tgaacaaaaa tcataagcaa
    22921 tggtataatc acaatatgaa tatagaaatg ggggaaaaca tttggataca aaagaagaac
    22981 agctacttat tgatttaact tctgcaaaag gagtacctgg aaatgaagaa gaggtaagag
    23041 aagtattcag agaatatgcc aaaccattcg ctgatgatat tttttatgac ggtttaggca
    23101 gtgtgattgc caaacatggt gctggcggag gccccaaggt ctttatttct ggacatatgg
    23161 acgaagttgg ttttatggta acaaaaataa ccgaaaaagg attcttggaa ttccaaactc
    23221 ttggaggttg gtgggggcaa gtcatgcttg ctcagcaagt tgaaatcaaa acacgtgaag
    23281 ggaaaatcgt ccacggtgtg attggttcca aaccaccaca tgttttaaca cctcaagtaa
    23341 gaaataaacc ttatgaaata aaggatatgt tcattgatat tggcgcatca agccaagaag
    23401 aagccaaaga gtggggcata cgtcctggag atatggtcac tccatatatt gaatacaaac
    23461 gaatgaatgg cagtaaatat ttactggcaa aagcatggga taatcgtatc gggacagctg
    23521 tttctctgcg agtattagag aatctatcta aagaagcaca cccaaatgtt ttattcgcag
    23581 gaagcgatgt gcaagaagaa gtaggcttgc gaggtgctcg aacaagtaca caccttgtaa
    23641 atcccgatat tgcttttgct ttagatactg gtacagcagg agacactcca ggaatgacac
    23701 caaaagaagc agattcgatt ttaggaaaag gcccacagat tttgattttt gatgcatcta
    23761 tgatcccgca taaaaaatta ttgaattttg ttattgatgt agcagaggaa atggatattc
    23821 cattccaata tacagtgatt tctggcggag gaactgatgc aggacaaatg catttgacaa
    23881 gagatggtgt tccgtctgta gccattaccg ttcctgttcg ttatctgcat tcccatacat
    23941 cagtgattca tgaagatgat tatttgaata cagtgaaact agtcacagaa ttagtgaaac
    24001 ggcttgatag tgaaacagtt gaaaaaattc ggagttatga ataatgaata atagaatacc
    24061 tatttctgaa tatcggaaaa aagcacgagt ttctttggaa aatcaatggg gaatcaatac
    24121 ttggcttgtt ttcttatcta taatatttac gagcgtcatc cagaactttt ttgacggttt
    24181 cagtcctttt ccggaagaaa gcatgcagca gcacttattg agttttctag tcgataattt
    24241 acttttattc gcattcaact atgcattgtt ttacattgcg ctagtagttg tacggggtgg
    24301 cagaccaaaa agtaaccttt tattttcagt tttccaaaga aagtattttg gttcgatact
    24361 tggcatcaat ttgatcaatt cagtcatcaa ctggctactc aacagtttaa tctttctgcc
    24421 catgttttta atcagcggag tgagtactta tatgcagctg cttttcagtt caaatgcggt
    24481 acctacgggt gtcatgccag aagattttct tgatatcagc tttgttttat cgatgatagg
    24541 gatgattttt gtttcagcac tcatcatgag tattgttggc ggtttattcc aatttgctgc
    24601 atggacaaag ttcgactatc ctgatttgtc ggttattcaa tgtttgaaat atggctggtt
    24661 tttattgaaa gatagaattg gtacgtatat tttgttgcag ctgtctttta tcggctggta
    24721 tttgctagga gcaatcgctt tgttcatcgg tcttttgtgg gtcattgttt atgtgaatgt
    24781 gtcagttgca gaattttatg aacaagcacg gattgaaaaa ggaggtccag acgcctattt
    24841 tacttagcat gtaagcagtt tattcatcaa aaaaataact tttgtggtag gataaatctt
    24901 tgagggggaa tgtacgatga aattaactgt tttaggatgc ttaggagcgt atccttataa
    24961 aaatcaaggg acaacaggtt atttgcttca atctgacggg ttcaatttgt tgatcgatgc
    25021 aggtagtgct acgctgatca aattacaaga acaccttgat ccacttgatc tagatgctgt
    25081 gatccttagc cattatcatc atgatcatat tgctgacctt ggtgtattac agtattactg
    25141 gcaacttcat cctaagagaa atccggagac attgctttca atttatggac acacaaaaga
    25201 ttccattcac tttgaagaat tgacgttgga aaatgtctca aaaggacatc cttattttga
    25261 agctgaagaa ttaaaaattg gtccttttct gattactttt atggaaacaa tccatccagt
    25321 agtatgttac gccatgcgta tcgtagaaga aacaacgggg aaagtattcg tatttacagg
    25381 tgattcaggt tatttggaaa gtttcgctga ttttgcgaaa gatgctgatt tgtttctagc
    25441 agatacctat ctttttgaag gaaatgaaca tcatcatgcc catttcactt caaaagaagc
    25501 tggagaactt gcgaaatcag ctaacgtaaa gaaacttgta cttacacacc tacctcagtt
    25561 tggtgattta gaacaattga aaaatgaagc gcaaaaggca gcaggcaaag ggattgatat
    25621 agaacttgct gcagttgaca aagtgtttaa catttaggag gaagaacatg atttttgtac
    25681 caaatgaaaa ccacgaccca agaatcaatt tagcaattga acaatatttg ctgcaagaaa
    25741 tgcctttaga tgaacctatt ttgctctttt atatcaatga accttcaatc atcatcggca
    25801 gaaaccaaaa tacgcttgaa gaaatcaatc gagattatgt ggaagaaaat ggcattcatg
    25861 ttgtccgtcg cttaagtgga ggcggagctg tctaccatga ttttggaaac ctgaacttta
    25921 gttttatcat gcctgatgat ggggattcat tccgtgactt tgcgaaagta acacagccaa
    25981 tcatccaagc acttcatgaa ttgggtgttg ctggggcgga attgaaaggc cgaaatgatc
    26041 tagtcattga tggcatgaaa ttttctggca acgcgatgta tgctaccaac ggtcggatgt
    26101 ttgctcatgg aacaattatg ttcgactctg atatcaatga agtagtcaat gcattaaaag
    26161 taaaaaaaga caaaatcgaa tcaaaaggaa tcaaatcgat ccgttctcgt gtaacgaata
    26221 tcaaaccatt tcttccagaa gaaaagcaaa aaatgacaac agaagaattt cgtcaagaaa
    26281 tcttgttgaa aattttcggc gtagagtcag tagaagaagt aaaaacgtac gaattgactg
    26341 atgaagattg gaaaaaaatc aatcgaatct ctgaggaata ttatcgaaat tgggattgga
    26401 attacgggaa gtctccagat ttcaatttct ctcgccaaaa acgtttttct atcggttcga
    26461 ttgaagtcca tttgaatgtc tcagaaggaa tgatcaaaga agcaaaaatc tttggcgatt
    26521 tcttcggact aggagatatc tctgacgtgg aaaaaaaatt ggttggacag aaatatgata
    26581 aagcatctct atcaaaaata gtcagccaaa ttgatgtgaa gaaatatttt ggtgcgatag
    26641 aaccagaaga attgcttacc ttactttatt gaaaataaaa aatagcggaa tccacatata
    26701 tggattccgc tattttttat acaggattcg ggtaatttcg agagagttga acagtgatcc
    26761 gatcaatgaa agtatctttt tcctgcgtta gtgttcctgt gtaacgatcc gctacgtctt
    26821 tcatcatcat taagtcaaaa cgttcctgat catctaattc ttctgtgatg cctcgactaa
    26881 ataggtttgt atcgtaatgt gcactatgtt cgcaacaaat gacgaaatgt tcctcttgtt
    26941 cgtgtatcga caaataaatt tttcgataca gtggattttc gatggcatga gtttctctaa
    27001 aggaatgctc taaagcgtgg atcaaaagtt gagccagatc gtcatcgttg ataggaagtt
    27061 cttcgggaag atctgcttgg aaggttatct gaatattccg tttggcagct aacttctggt
    27121 aacgcgctaa gataagattt gtcacctggt ggttgcaaaa agaacacagc atttcgaaat
    27181 tttttgcttc ttctaatatc ttttccacat agtttttagc ttttgtttgg tccgtatgca
    27241 ttaaatcttg cagattctcc atctcttgga caaattccag gcgaagtgta tttacttctt
    27301 ggatatgctg tcgaagctgc tcataatgtt gctccaacaa atcatttttg atttttaaga
    27361 aatctacttg tctccgatct ttgtcggtat ttaagatgtg atcgattaga ttgtagctga
    27421 taataacgat tagaatgata atatataaaa tcgtagacca attgatcgtt gtttgataga
    27481 tacctaatgc cgtttggatg taaatcaagc aatggataat ggctaccaag acgatccaag
    27541 gtgtacaagc tacataaaaa cggttattct tatatgcttc gccaatgcat gcaagtgaag
    27601 tgactaaagt gcttataaca ctagcaatat tagcaatcgg cattaattca ggaagttctg
    27661 caggagtaaa agttgcataa agcagaacgc cgataaaaat caaaagttgg aacgtacaaa
    27721 aaattccgta ccatttttta tagtaaaaca ttcggctcca atagtagcag atgatgaaag
    27781 ctgacgttaa gataataaat aaatgagata aaaaagaatg aacgaatggt tcaaaaagaa
    27841 taccacttaa aatatcttct gatacagctt caaatcctaa tgccaaagca aagcaactta
    27901 agagaataag tgagtattca agacgttttt gtttatacat caagtagatc gtatagaaaa
    27961 aggtccctat agcgataaaa acagcgatta tcatcgtcaa tacttgcggc actgattgtg
    28021 aataaataaa actaatcaat ggtccagttg ttcctagata aactttcggt ggcagtccag
    28081 catagttctg ataaggagat gagactgtaa gggtcaattt ttttccgata taatttgctg
    28141 gtaaatctat cacagccaat gagagtccgg gattgctttc ttcctgataa tctttccgtt
    28201 ggtataaaat cttttcgcct agatatacag taatccattg atggtttcct ttgattagta
    28261 aatttgcttc gtccaacggt ttttcaagtg tcgtttccat aatgaatgtt tcgtctttat
    28321 ccacggtagg aatcgtacga gtgtacttgc tgtcaaactt aaaatcagga tcatcttttg
    28381 tatagaaaac ccacgaatct tttatttctt tcatttgatt gctgtccgca ggagaaaaaa
    28441 taaaataaaa gaaataagca attcctgtta aaaataacaa tgataatata atgattatgc
    28501 tccactttat acgtaaataa aaagattctt ttttattata tatgttatta aaaaaagaca
    28561 taaaggtatt cc
//
LOCUS       DACGLI010000039        28083 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.040, whole genome shotgun sequence.
ACCESSION   DACGLI010000039 DACGLI010000000
VERSION     DACGLI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.040"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(19..600)
                     /locus_tag="IXT22_001838"
     CDS             complement(19..600)
                     /locus_tag="IXT22_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4863188.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(783..1409)
                     /locus_tag="IXT22_001839"
     CDS             complement(783..1409)
                     /locus_tag="IXT22_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4863189.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(1431..2762)
                     /locus_tag="IXT22_001840"
     CDS             complement(1431..2762)
                     /locus_tag="IXT22_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAQ4863190.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(2917..3318)
                     /locus_tag="IXT22_001841"
     CDS             complement(2917..3318)
                     /locus_tag="IXT22_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4863191.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(3404..3610)
                     /locus_tag="IXT22_001842"
     CDS             complement(3404..3610)
                     /locus_tag="IXT22_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863192.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(3705..5207)
                     /locus_tag="IXT22_001843"
     CDS             complement(3705..5207)
                     /locus_tag="IXT22_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAQ4863193.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(5225..5680)
                     /gene="argR"
                     /locus_tag="IXT22_001844"
     CDS             complement(5225..5680)
                     /gene="argR"
                     /locus_tag="IXT22_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4863194.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(5778..6395)
                     /locus_tag="IXT22_001845"
     CDS             complement(5778..6395)
                     /locus_tag="IXT22_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863195.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            6616..7989
                     /locus_tag="IXT22_001846"
     CDS             6616..7989
                     /locus_tag="IXT22_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4863196.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            8064..9176
                     /locus_tag="IXT22_001847"
     CDS             8064..9176
                     /locus_tag="IXT22_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAQ4863197.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(9248..10885)
                     /locus_tag="IXT22_001848"
     CDS             complement(9248..10885)
                     /locus_tag="IXT22_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAQ4863198.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(11053..11661)
                     /locus_tag="IXT22_001849"
     CDS             complement(11053..11661)
                     /locus_tag="IXT22_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4863199.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(12045..13196)
                     /gene="queG"
                     /locus_tag="IXT22_001850"
     CDS             complement(12045..13196)
                     /gene="queG"
                     /locus_tag="IXT22_001850"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAQ4863200.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(13215..13967)
                     /locus_tag="IXT22_001851"
     CDS             complement(13215..13967)
                     /locus_tag="IXT22_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863201.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(14108..15058)
                     /locus_tag="IXT22_001852"
     CDS             complement(14108..15058)
                     /locus_tag="IXT22_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863202.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(15059..15898)
                     /locus_tag="IXT22_001853"
     CDS             complement(15059..15898)
                     /locus_tag="IXT22_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4863203.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(15895..16641)
                     /locus_tag="IXT22_001854"
     CDS             complement(15895..16641)
                     /locus_tag="IXT22_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863204.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            16879..18249
                     /locus_tag="IXT22_001855"
     CDS             16879..18249
                     /locus_tag="IXT22_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4863205.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(18304..19200)
                     /locus_tag="IXT22_001856"
     CDS             complement(18304..19200)
                     /locus_tag="IXT22_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4863206.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(19481..20158)
                     /locus_tag="IXT22_001857"
     CDS             complement(19481..20158)
                     /locus_tag="IXT22_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4863207.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(20249..21154)
                     /locus_tag="IXT22_001858"
     CDS             complement(20249..21154)
                     /locus_tag="IXT22_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4863208.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            21329..22783
                     /locus_tag="IXT22_001859"
     CDS             21329..22783
                     /locus_tag="IXT22_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863209.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            22799..23830
                     /locus_tag="IXT22_001860"
     CDS             22799..23830
                     /locus_tag="IXT22_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4863210.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            23837..25024
                     /locus_tag="IXT22_001861"
     CDS             23837..25024
                     /locus_tag="IXT22_001861"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAQ4863211.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            25180..26562
                     /locus_tag="IXT22_001862"
     CDS             25180..26562
                     /locus_tag="IXT22_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4863212.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            26689..26919
                     /locus_tag="IXT22_001863"
     CDS             26689..26919
                     /locus_tag="IXT22_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863213.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(27119..27787)
                     /locus_tag="IXT22_001864"
     CDS             complement(27119..27787)
                     /locus_tag="IXT22_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAQ4863214.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(27976..>28083)
                     /locus_tag="IXT22_001865"
     CDS             complement(27976..>28083)
                     /locus_tag="IXT22_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4863215.1"
                     /translation="SAIDSYIYYYNNERIKQKLNWQSLVQFRKTTVTVV"
BASE COUNT         7814 a         5741 c         5161 g         9367 t
ORIGIN      
        1 tgtcacaacc tctaattatt aaagaacctt ttgcgaagtt aacaatcttt ctttgatcaa
       61 ttgaaaattc tgcctaagta gtgatagatc ctgtgtgact ttcaacaata agatacttcc
      121 ctggatttca gcaatcaacg ctttggcttg acggtctgct tcttcatcgg acagtttttc
      181 ttcagaaagt gccaggatat tttgtttcgt atacttgacc cattgattga ctaattctag
      241 tagcaacaga cggtattctt catccactgt actcaactca ataatcaaat tacctacagg
      301 acagccatga taagtgatct gtgtctcatg atcagcgaaa atccagtcca acatttcttc
      361 taatgcttct tctggctgtt ttccagcatt taagatgtct tcgaacaatt ctgtctgcca
      421 tacgtccata tgcgcatgga tcaccgctag acaaacttct ttttttgaag aaaagtaata
      481 ataaaattga ccttttcctg tatcagaagc tgctagaata tctcggattg acgtttcatg
      541 atagcctttt ttataaataa gatctttggt cgcttccaag atcttttcct ttgttttcaa
      601 tgatattctc ctttttcatt tctcatagtc ctatattata cagtaaattc atcatttttt
      661 cttcttaatc gtttaaaaaa gactgtgcca aattatctga cacagccctc actataaaac
      721 tgttctcata tagctagatg ttcattgatt caagaactgc gaggacaaaa gcaattccta
      781 tcttatgata gttgctctaa tacttcctct gttgtcatca cttgatctgc aataaagcca
      841 aagttcgtca acgctgcatc cattgcttct tggccaggag caccaattgc atctgtcgct
      901 accacaacat tgaatccact ctctaccaat tcacgcatat gggaatcgct acacaagttt
      961 ccgttcattc caccaagaat tactgtgtcg attccatttt ttctcaattg gagcgccaaa
     1021 tcattgcttt ctggtccaaa gattttatga ggagagctga tgatcgtatt ttcatccaaa
     1081 taaggtttca attcttcgat aaaatcggct cctgaacctt cttccactga ttcatattga
     1141 ctttttctag caaacatctg ctgctcaagc atcatatgtt ctcctgcacc gccaaattgc
     1201 catttatggt catgtgggta aaaataatga ggagaaataa agagtttgta tcctttttct
     1261 tttgcttgtt ttaccatttc aatcatattt tcgatcgtat tgtatttttc taagatatct
     1321 tttgtcaaac caaagccacc gcctgctggt ttcaagaact cgacttgcgg gtcagtgaga
     1381 actactgctg tatttttatt attgaacatg gtggattctc cattcgttat ttattttaat
     1441 acatcattta gagcttcact cattgtcgga tgagaataga tttgatctct caataacgta
     1501 taaggaagtt ttccattcat agctagcgaa atcaagttga tgacttcatg agaatcttcc
     1561 gcatagatac ttgcccctag aatcaagtca gtttcagggt cgactaaaac tttgaataca
     1621 cctttaggat cttctaatac ttgtgcttta gggacaccgc ttgtcatata cttgaataat
     1681 ttgtaattga cgccttgtgc tttggcttgt ttttctgtta aacctacatt ggataaagtc
     1741 ggagtgataa atacactgta aggcacagct ttccggttat tcgttgttcg tttattctcg
     1801 cccttcaact gatccataat gattcgataa tcatctagag agatataagt gaactgcaat
     1861 ccgcctttga cgtctccaat cgcccaaatg ttgtctgcat ctgtacgaag gtattcatcc
     1921 acagcgattg ctccgcgatc tgttagttta acatctgtat tttctaatcc aagtgatgct
     1981 gtacttggtt ttcttccagt tgcagccaaa acttttgacg cttggattgt tacttcttgg
     2041 ccatcttctg taaaggtgac ggcagctgtt gattcttggt ctgctacttg atctacagat
     2101 acacctagat ggaattcgat tcccgcattt gtcatgtctt ctaaaatcat ttgcgcgata
     2161 tcttcatctt cacgtggaag aaattcagaa tgggcatcaa gaacgacaac tttagatccg
     2221 tattcattga acattgatgc aaattccaag ccaatatatc cagccccgat gatcactaat
     2281 ttttccggta attgttcctg atccatcgct tgcgtagaat caatcaagta gcgacttgta
     2341 ttcaatcctt tgattggtaa aatgattggt tcagaaccag tattgatgaa aatccgttcg
     2401 ccttcaacaa tcactttttc accattattc gtcacttcga tttgatggtt agaaagaaaa
     2461 cgtgctgtac cgtccatcac tgtcccagtt gcctcatcgc tgatcatatg ataatttttg
     2521 gcgcgaagca tgcccgtcaa tttttctttc cgagcaacag cctctgtaaa gtcgattcct
     2581 ctttctccat tgaaaatcaa tgatttagaa ggaatacagc cgatgttgat acatgttccg
     2641 ccatacatac gtgttgactt ttcaacgact aaaaccgatt caccttttga agctaacgcc
     2701 ttcgctaaag tcttaccgcc ctttccaaaa ccgatcacaa tattttgata tttttccatc
     2761 atttttccct cgcttctttt ttacctaccg attggtacaa aaatatgata accgataatt
     2821 gtctattctc caaatcatct gctttatttg tcaaaaaaaa ccagacaaaa agcggtcctt
     2881 tcacgttttt agtctggttc gatttccttt attcttctaa acaatcgtta cttctacatc
     2941 gatatttcct ctagttgctt tggagtaagg gcagaattca tgcgcatctt ctgcaatttt
     3001 ttgggcttct tcttcgctga tgccatcgat atgcacttct aatactacac cgatctgata
     3061 gccgccatca tctaaattat aaagagagac acgtgctttt actgtggact ctgctgtcat
     3121 tcctgcttct ttgatcatat gttgtaccgc cccattgaaa caagaagcat aacctgctgc
     3181 aaataattgt tctggatttg ttccttctgc atggattcct ggaggagtga ttttcatatg
     3241 catcgagcca tttggtgcct cgacttctcc attgcgcccg ccatggttga tcattgctgt
     3301 ttcgtatgct tttttcattg tactgctcct ttcgattgac catttgctac ttggctataa
     3361 ttatagtgta tgacaagtaa ggcgctttct acaaaaattc tgcttattcg aataccagaa
     3421 tgccgtcttc tactattttt ccaaaaaaca aaaaaatact actcgtgaac aacagcgtca
     3481 tatttgttcc aaaataaata gcaatctttt ctacataatc ttttatatga ttgattttaa
     3541 gatacatata taccagaaag ttgaccccat aaaccaatac tgttaaaaaa ataaccatat
     3601 tcgttaccat tttttcctcc ttttgctggt ctccctacca gcactcgatt taaccatacc
     3661 actttttttg ccgtccaagc aactagcctt tcaaaaagac tggtttattc tgctgttaat
     3721 gattcaagat cagaaaaatg tccgaataat tttgctaatt ttactaacgc caacttgttc
     3781 tttccgaatt catcattttc tatctgtaat actagtaacg gctcatgtaa gcttaaacgg
     3841 atcaaaaacc agccgtttcc gtatggctct tctagatcat atcgaatacc ttcttcattt
     3901 tccgggtcga agttcatccc tttttcttct tccaacagtc gcttcatttc ttctaatatc
     3961 ttgtttcctt gttcgcgtgg ttcatcgctg aacaatttta atcggatttc ttgtacttct
     4021 acgggctgtt tcaactcttt gatttgttca tctaatgtga taccttttct ttttaattct
     4081 ggcaaaagca tcaggatctt tgcgatgaca tatgcaccat catccagaaa atagttttcc
     4141 ttgaatgcag cgtgtccgct tgtttcgatg gctagctgtg tatctttccc aagacggtta
     4201 agttctaatg ctttattgat tacatttcga tagccggaaa tataacgaac ttggatgcct
     4261 cctttttctt caatgaatct ttgtagatga gaagaagtag gggaattcgt cacgattctt
     4321 gttcctggat gctcttttaa tacgattgta cttaatactg cgatcaaatt atttcgattg
     4381 atcactgttc cagaagcact gacaactgca gaacgatcca catctgtatc gaaaatgatc
     4441 ccaagatctg cttcatttgc taaaacagcc tgcttgatac tttccatcgc ttctttatta
     4501 tcaggatttg ggatatgatt aggaaatcgg ccatctggtt ccaaaaattg ggaacctgtt
     4561 gaatccgcac ctaagctatt caatactttt tcagcaaaga atccaccagc accatttccg
     4621 gcatcaacaa tgattttcca accatttagt ggtttgcttt ctagtgttcc aatccccttt
     4681 ttaatttttg tgactaaatc ttgcgcataa ggtgtcaaaa ggtctgcttt ttctacgctt
     4741 ccagtttgtt cgctttttat tttttgctgc tgtgatagga taaaagcaat atcttctttt
     4801 tctgctcctc cttctgaggt aaagaatttt attccattat aataataggg aagatggcta
     4861 gcagtcagca taaccgcagc atcgcacgag aactgttcaa attgagtgga cataaacata
     4921 gcaggcgtag tagctaattc gaaatcgatg acatgtatcc cttgttcttt cagactttgg
     4981 atcaacgcct ctttcagtgc tggtccgctt atcctactgt catgaccaat cccaatcgtc
     5041 cattttttat ttggatcggt tgatttcttc tttttcttta tccagtttgc tagtccccag
     5101 ccgatctttt ttaccatgtc tgtcgtcaag tttacttcat atccttcaac tggtaatgcg
     5161 attcctcgaa tatccgatcc attttgcagc gctttcatat ctttcatata aaagtcctcc
     5221 tcatttattc cctcattttt tccagctttt ctgcaaatcg ctgtgcttct tcttctgagc
     5281 ggcaaataat aatgaatgta tctacaccgg ccatcgttcc gacaacttca gggtaagcca
     5341 cttcatctag ccaattcgtt accacatcgg caccatttcg ttcagtcaat acgataacca
     5401 tgaactgaac agactggata cgcaaaacct cgcgtctaat tgctgtacgc aaacgttctt
     5461 catttaaaga aacagatggc tggttaaata atgtatagcg tactattttg ttttcatttt
     5521 gactttttac taacttcatt tctcgaatgt ctcgagaaat cgttgcttga gtcacatcgg
     5581 cgcctgcttc atgcagccgc gcaagcagct cttcctgtgt cccaataggt tgttctgtaa
     5641 tgatctggcg gatcagtgct tgtcgctgtt tctttttcat attagacacc tctcaatgtt
     5701 gattatagca aaagataagt aatatttctt catattttgg tattttttac ttttattttt
     5761 tgttttcatt caggttgcta acctttttct attttaacac gcaaaatcgt cttcattttt
     5821 tcaggtgctg attttcttgg atcgctgatg taaatctctt tgtgttcttt agaagctctt
     5881 tcatagcctt cttttgcgat gaatgcttct aatttctcaa acgttgctgg ttcttcggca
     5941 tagggcccga cgtgtaagat ttgggcacaa agaccttctt ccatcttttt gaatactact
     6001 tgttctttca agtcttccgg aagtttgcta gaacgctgaa tggcttcttg tgctatcgct
     6061 tctgtaacaa agtcaggctg tcggatcatc aattgataag aaaaatgttc ttttttcatc
     6121 actggttcat gcaaatactt ttcttgcagt ccccattgtc cttccagtgg atagacagta
     6181 tacatctgat aatcaggaat cagccaattt tttttaggcg acatgcgtat tgcatagctg
     6241 actgcatata gacaggctac tcttcgttta aagtcttcct gattcgggtc gccgatccct
     6301 ctgatgctaa agaatgattt tttaggaacc tctagtattt gcgggctttt tttcatacta
     6361 tagctcttgt ctttacgcca ttcaattttt tccatttttc ttcctccgcg aaattccatt
     6421 tagttattta ttatcatacc tctttttgag tgacttggct aatcgtgttg acactatttt
     6481 tcagtttgtg ctagaataag tgaagtaaat aaatcgtaca gataacacgt ttcggcgtgt
     6541 cgagagagag gcggtttcta tttttataat agaaatcact ctcttttttt acgaaatttt
     6601 ttagaggtga tgtaaatgac aaaacaaaaa cagctgcttt tagtacctgc agtaattgca
     6661 acagggatga tgtcttttgc gggcgtattg atcgagacgg ccatgaatgt aactttccca
     6721 actcttatca gacagtttga tttaacgact gcacaagtcc aatgggtaac aacgatttat
     6781 cttttgatga tttcgatcat tgttccgctg tctacttatt tgaatcgcaa ttttagtctc
     6841 aaaaaactct ttttagcttc aaatctgctt ttcttggcag gtataatgat cgatttcttc
     6901 tctcctacct tcatggtcct attgtttggt cgattgctcc aaggtgcagc gacaggtatc
     6961 gctcttccgt tgatgttcca tattatcttg acatttgccc ccctcaatcg acgaggcgcg
     7021 atgatgggtg tcggtacttt gacaacggcc attgctccag caattggccc cacttatgga
     7081 ggcattatga cttcacattt tacatggaat catatcttcc tgtttcttgt gcccgttttg
     7141 tttctttctt tgattatcgg ctggtttgct attcccgaga tggcagtaca aaaaagtggt
     7201 tatttggatt ggataagcgt tttaggaatt tgtcttttgt ttagtggaag tctaacattt
     7261 ttgagtacgt tgggaacagt ttccagctgg attgctttaa tcatcggcgg tattggctgg
     7321 ttcctttttt actatcgaag taaaaaagtg gagcatccac tgatccgact gtctattctt
     7381 tcaaataaaa cattccgctt gtttttgatt ggcttcttag tttatcagtt tttattactt
     7441 ggtgtatctt ttgtcttgcc gaatttcctt cagatcgttc aaggaagtag tccttttgtc
     7501 gctggattag cgatgcttcc cggcgcagcg gttggtgctt tgctttctcc tttttccggg
     7561 aaaatgctgg atcaatatgg tccgaagaag ccaatttttg ctgggctgat tctttctttg
     7621 attggttggc tagcattatt cctactcata ggacacgctt cagtgggtgt attgattgct
     7681 tgtcatgtgt tttatatgat cggtatcgga ttatcttaca gcaatatgat gaccaccgga
     7741 atgaatgcac tgaatgaaga actacaagga gacgggaacg caatgttcaa taccttgcag
     7801 cagttttctg gcgctgtggc tacttcatta gtagcggtca ttatcaatta cgtccagcat
     7861 catacttccc ataactatga agtgtctact acattaggat caaaagcagc attaggcgtc
     7921 ttgttgctgt tgcttctcgt aagctttgct cgattcgcct attatctgtt ctttgctaaa
     7981 aaagcgtaga ttccatatac ggcaggtgtt gcatctgccg tttttttgtg tgaaaatggt
     8041 tgtttgtaaa aggaggcttt tttatggaaa aaattgccat tatcggtggc gggatcattg
     8101 gtatgaccct agccagttac ttagatacat caaaattcaa tgttgcttta tttgatgaag
     8161 ggacaggaca ggcaactaaa gctagcgctg ggattatctc cccttggttg tcgaaacgca
     8221 gaaacaaaca atggtatcgt ctggctaaag acggcgctgc ttttttccct aaacttataa
     8281 aagatttcca acttgatcaa acgatttacg cacaatcagg gacacttttg cttcgacctg
     8341 aaaaagattt agctgaattg gctgttcttg ccgagaaacg aaaagaagaa gcgccagaaa
     8401 ttggaaacat cgaatggctt tcacctgaac agacatctca agcacttccg ttattgaaac
     8461 cagcagtttc actgcgtatc agtggtggtg gtcgtctgga tggaaaagca tatttagaac
     8521 atcttggtca gcgtttagca caaaaacaaa tggagcagat ccaggcaaaa gtcactttgc
     8581 ataagaagag cgattcttgg ctcatcaagg gaccgtttgg agaatacaca gctgatcgtg
     8641 taattttgac acctggcccg gcacttaagc ctttattaca agaattaggc tatgctgcag
     8701 atatacgtcc gcaaaaaggg cagctcttag catttcagac atcttataag atgagtcaag
     8761 actggcctgt tgctatgctt gacggagaag ctgatttcat tcctttcatg gatggaaaga
     8821 tccttttagg tgctacccat gaaaacgatc aaggctggga tttggctcct actagcgaag
     8881 cttataaggg attgactaag agtacagaac agttcttgac tgatccagat cagataaaaa
     8941 actggccata cgagttccgt gtaggtaccc gtgcttatac gtcagatttt tccccatttt
     9001 tcggcgtact gccagatgat ccaagcttac tggctgctag cggtctaggc tcttctggct
     9061 tgaccacagg tccttatatc ggctatctat tagccaactt cttaaatact ggtcattggc
     9121 ctacggaaga ttatcaaaag gacatctcca cctatattac gaaaaatcca tcatagaaaa
     9181 acagcttttt caagtaagga tcccgagcga tattgcgcat ggattacttc ttgaaaaagc
     9241 tgttatttta gttcaatttc tgaatcaaat tctccaaact ttcttttgct tcatctggca
     9301 agagatcttt tcctatctga gcttcaatga atcgtaaacg aatatcaagt cgttgtttca
     9361 ccagattttt ataggacgta tcctcaaaag aaacaggaaa atctggtata ggtaaatagt
     9421 ggatgtcttc aaatggacca aacgacttga attctgccgt ttgttgcacg attctttcaa
     9481 cgattgacaa tgtcgtttca ggtttgattt ttttatcatc gaaatatcca gtattcagga
     9541 catagcaggc tgtttgctgt ttcaaaaaca actctcgaaa agcttgatag tcttccctaa
     9601 gaggatagac acggaaagga ttagcaaatg gttcaatgac tagctcatct agctgtcttt
     9661 ttgtagtgat attttccgcg tctgatcgtt ttgttgctaa tgttgcacca aaagacgctg
     9721 ctaaaactgg gtcattgatc ttgataattg gcggaagcga atcatctttc atgatccaaa
     9781 aaacagcatc gatcttttcg ctaagatgat cgactcggtc gggtgtcgca taacgtgatt
     9841 tgactgtccg cccatttccg tttcgtatat ctcctgttac taggactttt tctcctttac
     9901 ttgtacatgt cacgcccaca ttctgacaag taaggaaaga agaaatggcc ggatcatcag
     9961 acggatagtc ttgtgtttta tcaaagtaag aaggttccaa ggcagtagca aaaccatttt
    10021 ttcgagaaat aacgaaagca tcgtcatgca agatcgaaac agagtgacct tccgtatgtt
    10081 ttgctaaggt aatcgttgat tttccagaac cggacaaccc aaatacagcc atcgtatagg
    10141 tctggtcatt actagcatat tgtttcatcc caccgtggca ggcaataaag ccattgcgat
    10201 ttcccaatgc ccaagcaagc gtcaaagtcg ctttttttaa ttctccaaag taacgtaatc
    10261 ctagcacagc cgctgtatta tggagagcat caaacaaaat gagtccattt ggaaatgttt
    10321 catgtgtcca ttcgggatca caaaagatat aaagatctcc ctcatcaaag gaaacagact
    10381 tttgataagt ctctaagatc ttcgaattcg ctggctgaaa attcagcaaa taagaataca
    10441 aattgttctc aaatccttct ggaatcagca aatgactttg cacagaaaat tcttcagata
    10501 ggccaacgat tacttttgta tggtaaaact ggcgcttgcg actttgatac acagcttctc
    10561 ttaaaatttt ctcgtatttg ctttgttcct tgtctaagtc ctcaaagatc cgccgagcac
    10621 ttgctgttct tcccacaatg cttccatcat tgaatactag tgtcctaaca tcagctggta
    10681 aatctagttc ttcagcatgt gagattgtta aatctgtgat gatcgttcct ggactccctt
    10741 ttgctagttg ataagctgtc ttcctatcaa aaacttcatg aacattatta ccgtaaaatg
    10801 tcgtttctac aatcgatcga atactggata acagtggatt tccacttgtg atttcgttta
    10861 attcgagact ctcttttgta ctcatggctc ctcctcattc cctaaacaaa aaaacgtttt
    10921 ctttattata cattattcga gtttttattt gtactgctgc gctgtgggaa gcaaacgagt
    10981 tatttttcac acaaaaaaac cgagaacttg aataaacaag tttctcggtt tcatcatttt
    11041 ccttttatcg gcttagtacc agccgtttgc taaccagaat gttttagcag catcccatga
    11101 accataacga gatgttacat attgttctgc tacacgttct tgattggcag ctgaatagtc
    11161 gccgtttaag tatgaagcat ctaattgata acggccgatg taacgtccgt tagtagctgt
    11221 gtatgaaccg cctgattctt tttgtgcgat ccattctttt gcagagcttg aagttggcgc
    11281 tgttgcagca gctggggcag caggagctac ttcaactgtt tcaacaggtg caacgtatgt
    11341 atgttcttgc gttgctgttt cagttgtaga tgctgtattt tctgttgttt tgttttctgt
    11401 tgttgctgaa gaatcatttg aagttgggat tgttaattgt tcaccaacat aaatgcggtt
    11461 gatgtttgcg atcgaatttt tttcagcaat tgcatcgatc attgagttgt ctcctgcaaa
    11521 tttttgtgag atcttagata atgaatcacc tgattttact gtataaactt catcagcgtg
    11581 agcatttgta gttcctacaa acattgcagt agcaccagca gcaaaagttg tacctaaaac
    11641 aattttctta aatgaattca tattaaactc ctttttttct ccgtttttta ttctttcgac
    11701 gctattaact ttatcattta gaaatatttc ataggtaaaa gaaacatgac atttaatgac
    11761 aaaataacga attatttaat atttgtaaca tttaaacaaa tatttttttg atacaaaacc
    11821 ataaaagcct tgttgtataa gcaaagtaat cgtttttcta tgttttttta tttttgaatg
    11881 aaaaacgcag attctgtaac attcactgca ataatccata aaaaaaagca aaaaaatttt
    11941 tgatttttat caaattctct taaaaaaatg taaaaaatac aaaaaaacca gtaattgtta
    12001 caacaattac tggacaaaaa ctttgaataa tgttaactat ttttttattt taactttctc
    12061 cgcaataatt tctgggcatg ttccaattcg tttataacga cttcttctgt ttctttagct
    12121 aatatttcat ctaatacatc aagccatttt tccggttctt ttgttcctag acgtccaata
    12181 gcccaagctg ctgttcctct gatgacaggg cggacatctg ttaaacattc tgaaatctca
    12241 ggcaatgccg ttcgatcacc tagattagct aaagcaatca atgcgtttct ctgcaaaggt
    12301 ttcttcccac gccatgaacc agctaaatgc ccaaattgct gtttgaagtc tttattagac
    12361 atcgaaagca ttggctttaa ttttggatat atttcgtcta cttttggttc catctcttca
    12421 tgaaaatgaa aatcttttcc ttgattgtaa gggcagacta actggcagat atcacatcca
    12481 taaatgacat ttcgcatttt tttacgatat tcttccggca tcatcccttt tgtctgagtt
    12541 tgataagaca aacatcgctg ggcattcatt cttccgtcac caagcaatgc ttttgtcgga
    12601 caagcagtca cgcagcgcat acagtcaccg caaccaaatt ctcctggttt atcaggctca
    12661 aatacaatat tagtaacgat ctcaccaaga tagacaaatg aaccgaactc ttcagtgatc
    12721 aacaatccgt ttcgtccaat aaatcctaaa ccagctcgct gtgctacagc gacatcgatc
    12781 agttctccag tatctacttg cggagctaga cgccattcct cttctttttg ccatttttct
    12841 gctcttgttt ggatgaattc gatcaatcgg ttcaaacggt ctctgagtat atcatggtaa
    12901 tcgatccccc aagaagcacg agcaaactgc ccgcgttttt catccctagg cacttcttca
    12961 tggatcctag taggatacgc aagtgcaatg gaaatgatcg atttcggctg atcaaatgtc
    13021 atttctggat aaagacgctc atcgatattt ggatgttcaa agccagaagt atggccagct
    13081 gctttttgtt cttccaacga ttcttttaat gaatcaaaag gttccgccgt ggtgaacccg
    13141 attttgtcaa ttcctaatcg tttgctttct tgtatgattt cttcttttaa tgtcatggtc
    13201 ttcctcgctt gctgttaacg gctgtataac ccataatata gtttttcttt tttcagctgg
    13261 acaaactgga tctgctgatc ggcaatcttc ttttcttcca tccatttttt tcttgcagca
    13321 aatacttccc aataatttgt tgaaattaat tttcttttgt tatctaatgc attaaaaaaa
    13381 ttcaatgaaa ctggttttgt acttaacagt tcatggagcc ttacctcttc ccatggcgaa
    13441 aactcagaca gatcgcggga atacaatact tcttcataga gatttttttg ctgtgtgtac
    13501 gtgaatgttt gcgggatttt cccaggccta gcaatttcta ctagacgatt ataaaacata
    13561 ttcattaatt tgctgttggc aataaattga cttttataat aggccgactg gatctttttg
    13621 attactcctt ctgctttgat gactgaaaat aatgcaggcc atgctttgac ggttatttcg
    13681 tcgttttgtt taactaatac gccaggtgtg aagccgactg gagaaaggaa cacaaaataa
    13741 ccgataccgg tattttcatc taaaggctga aattcatcaa acaaccattt gcctatgtac
    13801 agctcttcat ctggttctgt tgtctcattt tgatttgcta tgaataattt agctaattct
    13861 gcttcaagaa attgaaggtc ttgatccttg tcggtatttt cctgctggct gatcaatcga
    13921 aagacttctt ctttaatcgt atatttatct ttacgtgtaa aattcatagc cacaccttcc
    13981 ttccttactc taactataac ggaatttctt caaaaaaggt atctgtacga cgaaaaacag
    14041 cataattttt tttcatatct cttataaaaa atgcaaggtc tgctcctcaa gctagacctt
    14101 gcacttttca gctttctttt gtttgtgaca aaccttcatg gatcgtttca atattccatt
    14161 tcatcatctg atagtaagaa tctccttgtt ctccttcttt tgctatggaa tcagtgaaca
    14221 gtttatcata gattttcaaa cccgtttctt ttgctacccg ttccatgctt cttgagtcta
    14281 cactggtttc cacgaataaa accggtactt cttttgctct tatctgatca atgatcgctt
    14341 tcatttgatc aggcgtacct tgactttctg tattgatctc ccatatataa gctgctggca
    14401 aatcatatgc tcgtgaaaaa tacttgaatg ccccttcact tgttactaat aattttttgt
    14461 tctcttcgat agaagcaaaa ctttccttcg cttgtgtatc taattctttt agtttttcca
    14521 catatgcttc tgcatttttt ttatagagtg tcgcattttc tgcatctttt tcagagaata
    14581 tacgtgcgat ttcctccaca tattttattc cgttagatag gtctagccaa gcatggggat
    14641 ctgcttttgt atgttcttca ccgctagtta aataaagagg ttctacattt ttgctaactg
    14701 caaaataatc ttttccttct tcttttttag ccgtttccat caagttatcg aaccagctgt
    14761 tacctgtttc aagattcaaa ccgttgtata aaataacatc tgcatcgctt gcctttttga
    14821 tgtcttctgg tagtacttca tattcatgcg gatctgttcc gactggtacg atactgtgga
    14881 tatctatttg atctgttccg acctcttttg ccatgtccgc caagatcgaa ttggtagcca
    14941 cgactgacaa cttttcttta cttccttcat ccgcttggtc agaagcctgc tttccgcaac
    15001 cggctaatac caagaaacta actgccaaga ttaaaaagag tgattttttt gttttcatct
    15061 atctgcttcc tttctgaaat aaaattcctt ttgttggaga aaataaaaaa gcaaggataa
    15121 aaaatgcggt acatgctaac acgatcgtag ctcctgatgg ccaattgtaa ctataactga
    15181 aaaacacacc gacaactgca cttagcatac cgattcctgc agctgtaatg atcattttca
    15241 gtaaatggtt cgttagcaag taagccgtgg cggctggtgt gatcaacatg gcaatcacca
    15301 agattgttcc tactgtctgt aaactgacta cagccactaa tgtcaaaaag aacatcaaaa
    15361 gataatggat cagcgatgtg ttcagcccat aagcttttgc cattgtcgga tcgaatgatg
    15421 tgatcttcaa ttctttataa aagaaaaaga caaatatcaa gacgattcca ctaacgagtg
    15481 ctgtcagcaa caaatcgctt tccctaacag ctaagacatt cccaaataaa atatgataca
    15541 aatctgtcgc actctgggca tatgaaatca agataatccc taatgcaaaa aaggagctaa
    15601 agacaattcc aatcgctgta tcatttttca atcggctccg ctgagtcacg aaaccaatca
    15661 ctgctgctgt tagcatccca aaagcagtgg ctccaaagat gtaactaaaa ccaaacatat
    15721 aagaaatggc tacacctgga agaactgcgt gagagatagc gtctcccatc aaagacatcc
    15781 ctcgtaaaat aataaaagaa ccgatgactc cagaagcaag tcctacaagc atggaagtga
    15841 ccaaagcgta ttgcaggaat tgataattca ttaatccatc aataaaggat tggatcattt
    15901 tttctctcct ccttttacta aatgtctgat gatctcacca taggccaatt gaaggttctt
    15961 cgatgtaaag acttcttgta ctggaccgga agcgatcagc tgtttattta aaagaataac
    16021 ctcatcgaaa tattcttcta ctttatgaag atcatgatgg acgatcaaaa tcgtttttcc
    16081 tgaattcttc aattcctgca agatgtcaaa gatctttcgt tcacttaacg catcaatccc
    16141 tacgaatggt tcatctaaaa agatccattc tgctccttgg gctagagctc ttgcaataaa
    16201 aactctctga agctgtccac ccgatagttc gctgatctgt cttttggcat attcttccat
    16261 ccctactttt ttcaaagctt gtcttgcacg ttctttttct tttttcccag gtctttgtcc
    16321 aattcgtaaa gatggatatg ttcctaaaag tacaacgcct aatacatcaa ttggaaagga
    16381 aagatccaat tcacttcgct gttccacgta ggctattttt ttacggactg agtttaccga
    16441 ctgtccagaa aaggtgactt taccagtagt agctggtatc aactctagca aagatttcat
    16501 aaatgttgat tttcctgcac cgtttggtcc gataataccg gtaatttttt gtggatttat
    16561 cgtcaagttg atagttttca aaacagtttt cccttgataa gcggctgaaa ggtcttgaat
    16621 tacaatggcc gtacgttcca aatcttacac tcctttttag gtttacctaa ctttttattt
    16681 aaatatagtt taactaaaat ggaaagcatt ttcaagtaga atgatgaaaa agtttttttc
    16741 gaattttcct cgcattttat gaaaattttc tgtagaatca catcaagagt tcaataaggc
    16801 taacctaata atgaaaaaca tgtgttgaaa cgtttgatta ttttttcttg ttgactcaac
    16861 aacgaaagga gtttttgtat ggaagaagaa aagttaactc gaagtcttag tgcccgtcat
    16921 atccaaatga tcgcactagg tggaacgatc ggtgtcggtc tgtttatggg tgcctcctca
    16981 accatacgtt ggacagggcc ctcagtgatg ggagcctatg cgattgcagg attctttttg
    17041 tatttgatta tgcgtgcttt aggcgaaatg ctttacgttg atccttcgac tggttctttt
    17101 gcaaattacg cgagcgagta catccatcct gtggctggct acttgaccgc ttggagtaat
    17161 atttttcaat atattgtcgt aggaataagt gaagtgattg ctgtaggatc ttatatgaat
    17221 tattggtggc ctgatttgcc ggcaattatt cccggaatca ttgtcgtctt gtttcttatg
    17281 ctggcaaatc ttatttctgt caaggcgttt ggcgaattag aattttggtt ttcgatcatc
    17341 aaagtcataa cgatcatttt gatgatcatt gcaggtcttg gggtaatctt atttggattt
    17401 ggtaatcatg gtcaggcagt agggatttca aatctttgga aaaatggtgg attcttcact
    17461 ggaggcgtca aaggattttt ctttgcatta tcgatcgttg ttgcttccta tcaaggaatc
    17521 gaactgatcg gaatgactgc tggtgaagca gagaatccta aaaagacgat cattgaagct
    17581 gtccagtcca ctatcggtcg aatcttgatt ttttatattg gtgctatttt tatcattgtg
    17641 agtatctatc cgtggaatca attgagtgag attggttcac cttttgtaca aactttttct
    17701 aaagtcggca ttacatttgc tgcaggactg attaattttg tcgtgattac agcggcatta
    17761 tcaggttgca attcagggat tttcagcgca agtcgtatgg tctatacact tgccataaat
    17821 ggaaagatgt ctaaaaaatt tctgaaacta tctcgtcacg gtgcgccttt ttatcctgtc
    17881 gtagcaatct caggtggaat cttaattggt ctgatcttaa attatcttct accaatgttc
    17941 atcaaccagt cagaaaatat tttcgttttc gtatacagct caagtatttt gcctggtatg
    18001 gttccttggg tagtgatttt gatcagcgag attcgcttca aaaagaagca cgcagataaa
    18061 atgcatgatc atccttttaa aatgccacta tctccttata cgaattatgt gacacttgct
    18121 tttttagcta tcgtattgat tttcatgttt atcaatcctg aaacgagaat ctcattgatt
    18181 attggactcg ttttcttgct ttacatgacg atccattact ttgtacgcga aaaaagaacc
    18241 ggaaaataaa aaaagaacga agcttcacct tagtggaagc ttcgttcttt tttattgctt
    18301 ttatcaattc aattttagcg tctcaccggg agtcaggaaa taattctcca tgctcatccc
    18361 attcagcgac aagatcgttt ctactggtac gccagttcgt tcggctattt gatttggacc
    18421 ttctccttcc aaaactacgg ttgtcgcagc ctgtgaagtc gcgctgttgg tattagtttc
    18481 agaggaatct gttgtgtctt gtgttgttcg agcttgcatt tcagaagctt ctaccgactc
    18541 tgctgtctca gaatcagaag atgttgtgtc ttgtgtgctt gttgactctg cttgaagaga
    18601 ggcgctagtc tgcaaataaa tatcggaaat cttagcgaca tgattcgtat aattagccga
    18661 taattgattg atcaaagtat ctaagtctac accgtcttta ttttctgctg cctgatacgc
    18721 tgcacgtaat tttctgatcc cttcgtcgga gattgcttga agctcacgtg ctttttggtt
    18781 agcaactgct gataaaccag ctattccctc ttgatttccc tgaatttctg tctggtattc
    18841 ttcaatcaat gcaggcgtct tttcttcgat ctttttcgaa taatcattta cgattgcttg
    18901 aagttgctct ggcaaaccat ttgctgtttt ttcttcagaa gtttgtgtct cttttgtttt
    18961 agttgatgac tcacttgttt gtttcgtctc tgttttcttt gtcgttgttt ccgttatggt
    19021 cgtacttttc gcttctgacg aattttttcc atgaaaatat agacccgcaa ctcctcctgc
    19081 tatgatcaaa aacacggcaa ctgctgcccc aatcatgatc atccgcttac gagctgcctg
    19141 tttttgctgt cttcttcggg tcatccgaac attttctccc cactcatttt catcatacat
    19201 ttttttcacc accaattttt atgtataata gcgttatcaa acgcttcata ttcttattgt
    19261 agcaaataat tgtcgctgtg cacattttta tctttgttat ttataagaaa atttcaccag
    19321 ttgagatgat tccaagattg tccgtcgatt tctccttgca gctgcattgt tcgttcgtct
    19381 atctcagcca tcagtttctt tatttcatat aagagcgcac ggtcttgata ttctgatttt
    19441 tcgcttaatt catctaattg ttggatcagc caatcatttg tcataatgaa gttcctttca
    19501 tttcttgcag tgtaaaggtc aagtcttcga tctgctcttt tgcctcagtc agtgcttcta
    19561 cgatatatgc ttgtttttca gattcttctt cctgcatttt ctgattttcc tgtactcttt
    19621 gaataaacca gtcaatccgc tgagtcagcg atggtttgcc ttccaatgag agatactgct
    19681 gataagcaat tagcttctcc caacgttttt cctgggataa atacataaat tgtgctaaaa
    19741 cgaatggcgg aagataggtc atatggaatt tatttgcgat tcgctgatac ggcctcaaaa
    19801 attcggaaat cgtatattct tcttttcctc cagcttggta ttctttttcc gccacacctg
    19861 ttgtcaatac gattcctagt tctttccctt ttaatacatg tgctgctcgt tccaagacat
    19921 tatcttgcca aatttttaaa tgagcaggag aactatacca gtaaaacgga aactggaaaa
    19981 tgatccgatc atgctgggcc aagagctgta gttcagtctc tatatctatt tttccgtctg
    20041 gataacttga ttccaaatga tgccaagtag ctggtaaacc agcagaagct tctttgaaaa
    20101 attgctgatt taaagattct tcgatcgttg gatggctaat gatgataagt gtacgcatcc
    20161 cttttcctcc tttttagtct tcgctttaca gtgtagcata accgccacaa gtttcttttg
    20221 ccgatgcttg tcattttaac cagactaatc aggttgtcca agaaactgcg gtttgttttt
    20281 ccaactgttt tttcaaggta tccaaagcaa tattcttaaa attttcgttt ttcatacgtt
    20341 tacgatagtt cgtagccgtt tctccggtac tctttttgaa cattcggcta aatacgacta
    20401 gactattgaa ccctacttga taggcaatac tttccacgga ttcatccgtc agagaaagaa
    20461 gaaacgcccc tcgattgatc cgtaccccga tcaaatattc cttgatactg gtacccatat
    20521 gatttttgaa tactcgcgac aaatggctcc gattgaccgc taaatgctgg gcgatttcct
    20581 caacagacaa tttttcagca taatgtgcct cgatgtattt gactgtttca acagctaaag
    20641 aggaatgaac cttttgtaca ccaccgctga cctttccgcc atcttttaaa aggactgata
    20701 aaaaacggta ggttaatgct gttaactgta attcattttc caaggtttct tccgtatctt
    20761 tcatgcattc taaaataatg tcgatatatt tttgtatgtc agaagagacc atcgtgtatt
    20821 ggtcttctct gaaaagcgac tgccgaatga tttcttctgc agcactccca ccaaatgaaa
    20881 gccagcaata catccacgga tcttctccat ctgataagta aaacgtcgag tctcctggac
    20941 gaatcaagaa cagatcacct tttttcaatt ggaattgttg atttttcaca tgataagatc
    21001 ctttgccttc catcacgaca tgcaggatgt aatcattgcg aatagcagga ccaaaagaat
    21061 gaaacggcat cgttttagag aaaccacaaa aatcaaaata caattctttt tctacttgtt
    21121 gatgttcctt ttttaaaaaa atcgattgct ccacgtctat ccctccttac tcctttagta
    21181 taatgcaaca aaaagttaaa taaaagtcac agaaatatat taaaaaggaa gcgatttctt
    21241 gttaagttta agtcattaaa agatctttgt tattcgttgt aaccggttta cttagtatta
    21301 tatattgaac aggagaggaa tacagattat gaaaagcaaa atgatccaac gtgtgtccta
    21361 cgctttaggc gcttttggac acgacacatt ctatgttaca ttaagcactt attttatggt
    21421 attcgtgaca agccagatgt tcgcaggaac agataaggca acgaatgcaa aaatgattgc
    21481 tacagttaca agcttagttg taggtatccg cttagttgaa attatttttg atcctttgat
    21541 tggtggcatc atcgataata ctcgtacaaa atacggtaaa ttcaaaccat ggttagttat
    21601 cggcggcgtt gttagttccg tactcttggt agcaatcttt accaatttct ttggcttagc
    21661 tactcataat acgactttat ttatcatatt atttgcaatc gttttcatct tattggatag
    21721 tttttattca tttaaggata tcgctttttg gtcaatgatt ccagctttga gtacggaaac
    21781 aaaggaacgt gaaaaatttg ctacgtttgc tcgtttcggc tcttctctag gtgcaaatgg
    21841 tactactcta gtcgttgtcc ctatcgttac tttctttacc tatcttgtta ctcataaaca
    21901 tattgaaggc gcttcaggct ggttctggtt cggtgtgatt gctgctgtta tttcaggcgg
    21961 tactgcgatt atcactgcct tgggcacaaa agaagtcgat actgcgatcc gtcagcaaaa
    22021 tgaaaaagct gggatcaaag atgtgttcaa agcagttgct caaaatgatc agttgatgtg
    22081 gcttgccctt gcttatatcg cttatgcgat tgccaatgta gcaacaactg ccgtattatt
    22141 ctacttcttc aaatatgtac ttggccaacc aactgaattt tggatcgttg gtctagttgc
    22201 tgccttactt ggtttagtag ctgttccact attcccaatg cttacacgcg tcatctctcg
    22261 tcgctacgtt taccttggag ggatcgcaat gatgatttct tcttactttt tctttacgat
    22321 cgcaggttca agtttgccaa tcgttatcat cgggctagta ttgttctact tccctcaaca
    22381 attgattttc ttatccgctt tgatgacgat cacagactct gttgaatatg gtcaatggaa
    22441 aaatggtatc cgtaacgaag ctgttactct atcaattcgc cctttactag ataaaatcgc
    22501 tggtgctttg tctaacggga tcgtagggtt tgtcgctatc gcttctggga tgactggtaa
    22561 tgctactgct gctgatatca ctgctcatgg cgtaacgact ttcaaagctt atgcattcta
    22621 tgctcctgct gctttgatga ttttctccgc tattattttt gcttggaaga ttacattgac
    22681 agagaaaaaa catgcacaaa tcgttgagaa attggaaaac aaattggctc cagctgatac
    22741 aatggaagat gaacttcacg atgcagtagt tccttcccat taagaaagga tcttgaaaat
    22801 gaagattaca gaaaaagatt ttggccaagg ttatcacttg ataaccttgg agaacaaaaa
    22861 caagctagca ctttctatct ctgatttagg tgctagaatc gtcagtttaa aatcaaatga
    22921 tcgagaatta gttttgggat ttgacaccgc tgaagaatat atcgaaaaag atccgtatat
    22981 cggtgcttct atcggtcgca ccgcagggag aatcgaaaat ggccgctttt ctctcaatgg
    23041 aaaaacttac caattagcca cagatccaaa aactggacat aatctgcatg gtggtgctcc
    23101 tggatttgaa ttaaaaaaat ggtcttatgt cattttgaat ggcgaaaatg aagcttctgt
    23161 catttttact actacaagtc ccgacggaga acatggtttt ccaggtacaa tggatgtgga
    23221 aatccgctat actttgacaa aagataatat ctggcgagtg acctctcgcg gcaccagtga
    23281 ccaagatact ttattcaatc cgacaaatca tgtttacttc aacttgacgg gagatgcttc
    23341 tcagtcaatc gatcaacatg agctttggct caatagcgaa gcttatgctc ctttgcgaac
    23401 agatagtatt cctatagggg taaaagaaaa tgctgcagga agtgctttcg attttcaaat
    23461 acctaaaaaa ttagcgtccg tttttgctag tgatttggat caaaaaaatc ttgttgacgg
    23521 aatcgatcat ccatttttct taaaagaaac cggcttgggt aaagaagccg ctcgcttgac
    23581 tagccccgat aaaagaatcc aagtagatat tgctacagat gcttctagtg tggttatttt
    23641 cactgcaaat ttcggcacag aaacaccaga aatgcgcaac cgaaaactgg cacatcacgg
    23701 tggcatcaca tttgagactc aaacagctcc aggtgcagag cgcttctcag catttggttc
    23761 gattcattta aaagccggat cagtatttga aacagtaaca gaattcaaaa tcaaaacaag
    23821 aaaggaataa ctcatcatgg aaatcaaaag aagcttaaac acaaaatttg ccgaaacatt
    23881 cggacctaaa aaaactacac aatacttctc accaggacgc atcaatttga ttggtgaaca
    23941 cacagattac aatggaggcc atgtcttccc cgcttccatc acttatggaa cgcaaggtgt
    24001 agcagcacct cgagacgata ataaaatatt agtttattcc acaaactttg acgatatcgg
    24061 tgtcattagt tttactttag atgagctaga atatgataaa aaagcaaact gggcaaatta
    24121 cgtaaaagga atggtcctta aattaaaaga agctggacac tcaatcgatc atgggtttga
    24181 gttattagtg gaaggaacaa tccctaatgg tgcaggactt tccagtagcg cttcattaga
    24241 attattagta ggtgttgtat tagaagatct gtttgattta aaaacagatc gcttggaact
    24301 agtccaaaca ggtaaaaaag tagaaaatga attcatcggt gtcaattcag gtatcatgga
    24361 tcagtttgcc atcggcttcg gtgagctaga tcatgcaatc ttattagata caaatacgct
    24421 gaaatacgaa atggttccag tgaaactaga tggttatgca atcgtcatca tgaatacgaa
    24481 taagcggcgg gaattggcag attcaaaata caatgaacgc cgtagcgaat gcgaagaagc
    24541 cttggcacgt ttgcaaaaaa ctttgcctat ctcttcttta ggagacttag atgaagaaga
    24601 atttgaatca actattgacc aaatcggcga tgatacattg atacgcagag ctcgccatgc
    24661 cgtttctgaa aatcagcgga ctttgaaggc aaaagctgaa ttagaagctg ggaacttaga
    24721 agcatttggt caactgttaa atgattctca ccactctctt cgctatgatt atgaagtaac
    24781 tgggatcgaa ttagatacac tagtagatgc tgctcaaaaa caagaaggtg tcttaggtgc
    24841 acgaatgaca ggagctggat ttggtggctg tgcgattgct cttgtcaaag aagaaaatat
    24901 acctgccttc aaaaacaatg tctatgatga atacatgaaa gttgtcggct atgctccgga
    24961 attttatgtt gcacacattg gaaatgggac aacaaagatc gatccagaag ctgttcatgt
    25021 ttgataaaaa aatcaacgat ctcagctaaa aacaaataga taaaaataac ctctcagcaa
    25081 tttccaaatg tgagcctttt gctcgtattt gaaaattgct gttttttatt gacacggaaa
    25141 gagaacgtgt gttctaattg tgttgaagag gtgattgtta tgtgggcgaa tcaaaatccg
    25201 gtatttgttt atgaaaaaga accttcaaga gatattttat gtattgactg caaatctttt
    25261 tacgcctccg tagagtgcgt tgaaaaggat cttgatcccc ttacaactaa attagtagtc
    25321 atgtcctatc cgtccgattc gacagaaaca cggggtagcg gattaatctt ggcttccagt
    25381 cctgcagcaa aaaaagctta cggcatcacc aatatcagcc gtgccagaga tcttcccttc
    25441 ccctatccaa gtgatttata tattgttgcc ccaaggatgg cctattatat ggaaaagaac
    25501 agagaaatca attctatcta taaaaaatat gcagacgaag cgaaccatca tgtctattcc
    25561 gtcgatgaaa gcttccttga tgtaacaaat agcatggcac tctttggtaa aacaaatgcg
    25621 tacgacatgg ctaaactgat ccataaagat gtgtttgagc agaccggaat ctacacgact
    25681 ataggaattg gcgataaccc gctacttgct aaactagcct tagacaatgg ctcaaaagac
    25741 ggaaagcaaa tgtttgctga atggcgttat gaagatgtac cagaaaagtt atggaaaatc
    25801 tcagatatca ctgacttttg gggaatcggc aaacgaacag caaaacgtct gaaacaaatg
    25861 ggtatacatt ctgtttatga tttagctcac gcggattatt atcacttgaa aagcaagcta
    25921 ggggtcatcg gtactcagct ttatgcccat gcttggggca tcgatcgaag ttttttggga
    25981 caagaatata caccaaaatc aaaaagtatc ggaaatagtc aaatcctaga tagagattat
    26041 acaagacgag aagaaatcga gatcgttatc aaagaaatgg ccgaccaagt cggcactcgc
    26101 ttgagacgat ctgcagcaaa aacacaagta gtcagcttat gggtaggata ctctttaggc
    26161 tatcttgatc caaatggcaa gaccgggttt caccagcaaa tgaaaatcga agcgacaaat
    26221 gctagcagag atctagcaga tgctttattg accattttcc accagcatta ccactaccag
    26281 gatattcggc gtgtaggcgt gaactgttcc gacctcgtat acgcgacagg tttacagctt
    26341 aacctttttg aagatcctga aaagcagata aatgaagcga aagttgattt tgttgtcgat
    26401 acgattagaa aaaaatacgg ctttcaatca atcatccatg cgcatagtct cttgcaagga
    26461 ggacgcgcca tcgcacgtag ttctctcgtt ggcgggcatg caggtggtat gagtggatta
    26521 gaaggtggaa aagatgagac ggacagcaaa aaaattcatt gactataacg agtatcgaga
    26581 tcggccattt ggattaaaat gggggactgc ttttgcgatg gaagaactag tcaacggtat
    26641 caaaaaaatg aagaagaagc acgcaaacag cctcttccta aacaacaaat gacattgcaa
    26701 gaaatcgata gtatactgac agaagccttt ttatctcgta aagcagtaat cattcagctc
    26761 aatttaaaag atgaatttgg aagactcttg gatgaggtcg aagggcactt cattggtgaa
    26821 gcctatgaag attactttat gattgaccat cagccgatat tgtgggaaga cgtacggtat
    26881 attgagttaa aggaaacaaa aaaatggttt gtgacatgag aggttgtgac agaagtgatc
    26941 aacttcaaaa aataagaaag gatttttcga aaattgcttc ttaaattttt gtggaatttt
    27001 ggcttatttt tcgaagaagc aacttctgga acaacgtata ttagatatca gaggttgtga
    27061 aaaagtcgct tagttttgag taacaagcca aggcgctgat ttcacaacct ctgtctatct
    27121 atccatctat tcggtaagat tcatgcatga cgtcttcttt atttagtatg tagagccctt
    27181 tttcttctga ccattcaaca taaatcagct gttttacatc tgcatagcct tctttcttca
    27241 agttctccat aagccatgct tcagtcaatt gattggactg aagcacttta tgctgaattt
    27301 gcccttcatc tacaagcagg atcgataaag ctttgtcttc atctgatttt ttcaatacac
    27361 tcatttgacc ggcattctct aggataacat gtttggcatt ttcaagaaaa aagcattctt
    27421 gctgtcttaa gattgctcgc aactgctcca tctcgatatg gttatttgtc aactctgtca
    27481 tgttgatgac gccgtctttg attagaacag atggctcgcc tttgacccaa cgattgacct
    27541 tttcattttt ttggacgata cgttcgatac cataaatcat tactgcccaa agcgcaatgg
    27601 caaataggac atgccctaca tggacattgt catcataggt tgattcttct aagatcccac
    27661 ctaaaacaag cgtatagact aaatcaaacg gtgtgatttc tgacatggat ttcttcccaa
    27721 gcaaacgtac cactaataat aaaccgatca acccgaacac cagtttcatt gtaattgaaa
    27781 aaatcatttt ttctccccct aactatctgt taattaaatt atatatgctt tctcacgaac
    27841 acgcatggaa tatacaagga agaaatgtat ccttttacta aaaaaaggac tgtgacactg
    27901 tagtgacccc caaaagttag acttttttgg agtggagaaa tccactcctt ttttttatgc
    27961 tctaaaatga tatttttaca caaccgttac ggttgtttta cgaaattgga cgagactttg
    28021 ccagtttaat ttctgtttta tccgttcatt attgtagtaa tagatatagc tatcgatggc
    28081 tga
//
LOCUS       DACGLI010000040        27788 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.041, whole genome shotgun sequence.
ACCESSION   DACGLI010000040 DACGLI010000000
VERSION     DACGLI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.041"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(48..1112)
                     /locus_tag="IXT22_001866"
     CDS             complement(48..1112)
                     /locus_tag="IXT22_001866"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAQ4863216.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(1109..2194)
                     /locus_tag="IXT22_001867"
     CDS             complement(1109..2194)
                     /locus_tag="IXT22_001867"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAQ4863217.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(2207..3184)
                     /gene="mvaD"
                     /locus_tag="IXT22_001868"
     CDS             complement(2207..3184)
                     /gene="mvaD"
                     /locus_tag="IXT22_001868"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAQ4863218.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(3177..4121)
                     /gene="mvk"
                     /locus_tag="IXT22_001869"
     CDS             complement(3177..4121)
                     /gene="mvk"
                     /locus_tag="IXT22_001869"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAQ4863219.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            4443..5096
                     /locus_tag="IXT22_001870"
     CDS             4443..5096
                     /locus_tag="IXT22_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4863220.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            5181..6086
                     /locus_tag="IXT22_001871"
     CDS             5181..6086
                     /locus_tag="IXT22_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4863221.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(6088..6720)
                     /locus_tag="IXT22_001872"
     CDS             complement(6088..6720)
                     /locus_tag="IXT22_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4863222.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            7040..7564
                     /gene="infC"
                     /locus_tag="IXT22_001873"
     CDS             7040..7564
                     /gene="infC"
                     /locus_tag="IXT22_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAQ4863223.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            7636..7836
                     /gene="rpmI"
                     /locus_tag="IXT22_001874"
     CDS             7636..7836
                     /gene="rpmI"
                     /locus_tag="IXT22_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAQ4863224.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            7889..8248
                     /gene="rplT"
                     /locus_tag="IXT22_001875"
     CDS             7889..8248
                     /gene="rplT"
                     /locus_tag="IXT22_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAQ4863225.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            8500..9837
                     /locus_tag="IXT22_001876"
     CDS             8500..9837
                     /locus_tag="IXT22_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAQ4863226.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            9885..12014
                     /locus_tag="IXT22_001877"
     CDS             9885..12014
                     /locus_tag="IXT22_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAQ4863227.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            11989..12678
                     /locus_tag="IXT22_001878"
     CDS             11989..12678
                     /locus_tag="IXT22_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863228.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(13086..13772)
                     /locus_tag="IXT22_001879"
     CDS             complement(13086..13772)
                     /locus_tag="IXT22_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4863229.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QVKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(13908..14102)
                     /locus_tag="IXT22_001880"
     CDS             complement(13908..14102)
                     /locus_tag="IXT22_001880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863230.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(14152..14592)
                     /locus_tag="IXT22_001881"
     CDS             complement(14152..14592)
                     /locus_tag="IXT22_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAQ4863231.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(14596..15441)
                     /locus_tag="IXT22_001882"
     CDS             complement(14596..15441)
                     /locus_tag="IXT22_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAQ4863232.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            15590..17008
                     /gene="pepV"
                     /locus_tag="IXT22_001883"
     CDS             15590..17008
                     /gene="pepV"
                     /locus_tag="IXT22_001883"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAQ4863233.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(17065..18012)
                     /locus_tag="IXT22_001884"
     CDS             complement(17065..18012)
                     /locus_tag="IXT22_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863234.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(18235..18585)
                     /locus_tag="IXT22_001885"
     CDS             complement(18235..18585)
                     /locus_tag="IXT22_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4863235.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            18785..19864
                     /gene="pepA"
                     /locus_tag="IXT22_001886"
     CDS             18785..19864
                     /gene="pepA"
                     /locus_tag="IXT22_001886"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAQ4863236.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20008..20328
                     /locus_tag="IXT22_001887"
     CDS             20008..20328
                     /locus_tag="IXT22_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4863237.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            20350..20814
                     /locus_tag="IXT22_001888"
     CDS             20350..20814
                     /locus_tag="IXT22_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4863238.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            21019..21624
                     /locus_tag="IXT22_001889"
     CDS             21019..21624
                     /locus_tag="IXT22_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAQ4863239.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(21663..22952)
                     /locus_tag="IXT22_001890"
     CDS             complement(21663..22952)
                     /locus_tag="IXT22_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4863240.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            23380..23859
                     /gene="rlmH"
                     /locus_tag="IXT22_001891"
     CDS             23380..23859
                     /gene="rlmH"
                     /locus_tag="IXT22_001891"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAQ4863241.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            24212..24526
                     /locus_tag="IXT22_001892"
     CDS             24212..24526
                     /locus_tag="IXT22_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4863242.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            24542..24928
                     /locus_tag="IXT22_001893"
     CDS             24542..24928
                     /locus_tag="IXT22_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4863243.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            24957..26342
                     /locus_tag="IXT22_001894"
     CDS             24957..26342
                     /locus_tag="IXT22_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4863244.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            26345..26498
                     /locus_tag="IXT22_001895"
                     /pseudo
     CDS             26345..26498
                     /locus_tag="IXT22_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            26521..27726
                     /locus_tag="IXT22_001896"
     CDS             26521..27726
                     /locus_tag="IXT22_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4863245.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
BASE COUNT         8643 a         5257 c         5741 g         8147 t
ORIGIN      
        1 tacttccgcc gtttgtacgt gtttagagcg tgagacaaaa gtgttcttta cttttgtccc
       61 acgctctttt ctgtgcgtct tccatacttc actaagtcga tccctcttgc ttcgcaccaa
      121 tccttcactg gtccggaaaa gatcagagat tgttggtgta gggccgcggt attcgttgcg
      181 ccgaccatag tataaagcag acgaagctct tcttgccatt gcttcatcag tataatagtt
      241 tcttctacgc cgtgattcat cagatgcgtc agtacggttc ctgaagtacc cacggcattt
      301 gcgccgagac aaagggcttt aaatatgtca taggcattgc ggatacctcc ggaggctagg
      361 atttccatag aagtgtctgc ttcatttgct tcaagcaatg aagagactgt cgattgcccc
      421 cagtcagcta aataactcag ttcccgcttg gagcgacggg cgttttcgat ctgggtgaag
      481 cttgttccgc ttcgaccgct gatatcaact gtatgaactc ctaaagcagc tagatcattg
      541 agcgtttctc ttgtcatgcc aaaaccgact tcttttacga tgagggggac gtcaatggct
      601 gtttgagttt cttgaataag tactttccaa ttggtaaaat cacggtctcc ctcaggcata
      661 accaactctt gaggtgcatt caaatgaatc tgtaaggcat ctgcgtgaaa caatcggata
      721 gcttctttgg ctctttcgac agaagtccct gcaccgatgt tggcaatgat tttcccgtga
      781 ggatattctt gtcgcataat cgtataagta tcggctaaag aagggacttt caaggcagcg
      841 ctgactgaac cagtggcaat catcaaatct gcttctcttg cgacgattgc aagatcttgg
      901 ttgatttttt ttgttttttc gcttccgcca gtcatcgcat tgatataaaa tgggctgctt
      961 agtgtaaacc caactgcctg tgtacttaga tcgacatcag aaactgctat ttgcggcaaa
     1021 gggttatgga tgatccgtac gaagtcaaat tcgttttttt gtttatcatg aaaggcttta
     1081 gctagtgaaa catgttcgtc ttttcgattc atcggttttc ctttctttga tcgctataga
     1141 catgtaacgg cagtggagtg atttctgctt tttcccatgc actcattaaa ggaagaatgc
     1201 cagatttctg gtcaacaatt acgattccgc aatcgccccc acctgcacca gaagattttg
     1261 cggctccttc atactgttca gctaaattac acaatttgtt caaagcaggc gtttcgatga
     1321 cgaccccagt gattgcagat aaatcatgca gtaattgtcg gttttttcga atcatctgtt
     1381 ggatcaacgt tacattattt tctttaaacc ctttgatcat ttcgttgaca cattctgtac
     1441 tattttttaa gaaaagctga taagccacca ttttatcttc tctcgaacgg tgaacttgat
     1501 cgaccaaatc agaagtagag gcagggctac ccgtccaacc aatcaataaa cgtaaatctt
     1561 caggagcaat caatggctca atggatagac ctggccaatc cagggcaagt aactcactga
     1621 tagaatgctg agtttcttgt tcttggagcc aaggatggtc gaaggttgag aaagcgatcc
     1681 agccaccata acagctagca gcgatgtcgc cgcaggaacc attatcttga actgctaaat
     1741 tggctagtgc tgcaatcttg aaaatctcca actgagataa attcaacgcg taaaaaacat
     1801 tcaaggcttt gaccgttgca acggtcacgg caccgctaga acccaatcca tatttccggc
     1861 catttgaact gtctaactca cttgttactt tcagatcata aaaggataaa agaatgtttt
     1921 tttcttgtgc atacttttca gtcaagcgaa tagcagcaag gatataatga aaaggatttt
     1981 cccgaatatc taaaactaat tctccgttgc gtcttgtcca acgtacaggc atcccactat
     2041 attgtgcaga ttggatactt ccgacttttc gtgcagattc tacagtgact gtcacgaatt
     2101 gatcgactgc agcgataact gctggatggc ctgtttcaac aactgcatat tctccggcaa
     2161 tatagagttt gcctggtgca gatacttcaa tcataaaaat ctccctttat tcaataatcg
     2221 caattcctgg accagcatgt gcagtaatta cttgttcttt gctaaataat ttggtaaatg
     2281 tttcttgtac ctcagataaa tggctgtttt ccactaaaac tttgacatta gggccagcat
     2341 ccatcgtaaa gtagcatgga atgccttgct ttctcaattg tcgcaccgca tccatcgctt
     2401 ttaagctgtc aggagaccag taagtgaatg gaggctgggc agctaaagtc gttccatgca
     2461 tttttagtcc gtttctttcc atcgtttctc cgagaagttg gaaatctttt gttttgattg
     2521 cttgtttcaa ttgatataga tccccttcaa cggaatctaa ccagccttga taaaaactgg
     2581 atgtttcgac tgtccgacgc atcccatttc tgctggacac ttcttttttc tggtcgttga
     2641 tcaaaacgaa aaccattgct aaatcgtctt cgaaagaatc ggaagggact ggcttagcgt
     2701 aagaacttaa gtcgtcatgg cctttttccc attcgacgaa accaccgaaa atacttcggc
     2761 aagctgaacc agacccgcgt cgagcaaatc ttgaaagaga gagatcatct aatccaagct
     2821 taagagcagt attgcaagcg cctgctaaag cagctagccc gctggcagag gaggctaatc
     2881 cagctgcggt aggaacgaaa ttctgactga ttactgaagc ttttagtgag aggccggctt
     2941 ctttacgaaa aaggtcaaga aactgactga ctttttttgt tgctttttcg tcttgcaagg
     3001 tgccatctag ataaaattca tctaccatat agctatcaga aaagatgact tctgtctctg
     3061 tataaaatgc atccaatgtt aacgaaaggc tgttgttcat tggaaggatg agttcttcat
     3121 ttttcttacc ccaatatttg attagagcaa tgttggtata tgcgcgtgct ttgcctttaa
     3181 acataggtat gtactcctaa tccttgtatc caagtttcag cagcacccgc atcttcaagt
     3241 gcttgactga tttcttgggc ttttgttttt gtttgtgcta atgcaatcat acagccaccg
     3301 cgtccaccgc cagttaattt ggcacccaat gccccggtat cttttgctgt ttggatcaat
     3361 agattaagaa aatcattgct gattgtcagc ttttccagaa gtgattgtga ttcatccatt
     3421 gtctgtgcca acgtttctgg tgaattttca atgattgctt gttttgcttg cttcgtcaag
     3481 tatcctaatt tttggatcat ttgtccagtt tcatgaggct gggtttcaaa gaggtgagcg
     3541 acatctttga cggcttctct tgtttgtcct ttgattcctg tatcagcgac aatcaaaaaa
     3601 gcatcgatgt tcaaagaaaa gtagtcgaaa ggatgccctt ttgtaaaata aatcggctgc
     3661 aagctgctag tagcggctgc atcgattcca ctaggattac cgtgggcgat tttttccgaa
     3721 agctggacat tttctaatag tatttcacga gacaaaggaa atgctaagta atcataaaaa
     3781 gcacgagtga ctgctgtggc gactgcagcg cttgatccca ttccacgttc agcaggaatc
     3841 gtgctttcaa tggtcagttg caagtttttt tggatgtcat gctgtttttt taagtgaatg
     3901 aataattttt tgatattttt taatgcatga ggagcttcgg ctaaatttcc tgaatagtag
     3961 gaagaaacca gttgatcgtc cattgcatcc agctcttcaa ggaatgcggt gacttttgtt
     4021 gcatagaaag gaaaggcaat cgctggttct ccataaacaa ccgcgtgctc gcccatcaat
     4081 atgatctttc cgcttgattc tccttggcca tagtttgcca taatctaact ccttctcacg
     4141 taaaagtgat ttttaagcaa aaaataaagc gcccaaaacg agttgcgctg cttcacgaat
     4201 ttttttgtcc actaagggtc tcaaaaaaca ttcctccttt attttactaa aaccatctca
     4261 gaagtaaaac taagaatacg ttttctaaag aaaaaacact tttttcttaa gaattttttg
     4321 actttttttc ttctttgact agaaaaaaat acaattgaca ctactagata ttgggggtat
     4381 atttaaaaag gttggagtta aacacaatat ttagtgatga agtgagctgg aggtaaatga
     4441 gcgtgatcgt tttagcaggt acaattggtg ccggaaaatc aagtttaaca gaaatgatgg
     4501 ctgaacactt tgatagtcag gcattttatg aatcgattga tgataatgaa gtcttgccct
     4561 tattttatgc aaaccctgaa cagtatgctt ttttgctgca aatttatttt ttgaataaac
     4621 gttttgcaag catcaaacaa gcaatgaaag atgacaataa tgtattggac cgttcgattt
     4681 atgaagattc actgcttttc catctaaatg cagatctagg aagagcaaca gaaacagaag
     4741 ttcgtgtgta tgatgaactg ctggaaaaca tgatggaaga acttccctat gctgcccata
     4801 aaaaacatcc ggatttatta gttcatattc gtgtatcttt tgatacgatg ttggagcgta
     4861 tcgaaaaacg tggtcgttcg tatgaacaat tgtcctttga tccaagtcta tacgattatt
     4921 acaaagaatt gaacagacgt tacgatcaat ggtatgaaga atacaaagaa agtccaaaaa
     4981 tccaaatcga tggagaccgc tataattttg tggaagatcc tcaagcaaaa gaagaagtct
     5041 tgaaaatgat cgaagaaaaa ttagcagaga ttcgccaaac caaagtagcc atttgattta
     5101 cagttgctca aataaagggt aaacctttat ttgagcgact tttttcttta tactggaaac
     5161 aaatgtcagg aggatagagt atgcgggaaa aacactattt taatcaagac cgtaattttt
     5221 ggatcaatgt acagcaaaac gatgtgctag ctgttaaaaa cttaaaagaa gaatatggca
     5281 ttagtgacga gatgctgact tattctctag ataaaaatga acgggcgcgc gtagagtacg
     5341 attcttttga tgaagcgtta ctgcttgtat caaatgttcc gcaccagcaa aaagtcgata
     5401 atcattatga aactagtcct atcgctttta ttttaaaaga agacggtttg tttacattta
     5461 ccacgccgaa taccgagtac gtgattcgac taattcgatc gcttttggaa cgaatgccag
     5521 acatgagtgt atacagttta ttgtttcgta cattgttttt gatttctgat tccttttttc
     5581 ctttaatcga ggaagtgaat agtgaacgtc agcggcttaa tctgaaatta agagaaaaaa
     5641 caacgaacaa gaatctgctg caactttcag atttagagat cggtttggtt tacttagtta
     5701 caggaacaaa acaaaatgta gtacttttag aacaaatcaa ggcattggct atttatcgca
     5761 agttgtcaga aaaggaaaaa gaagagttgg acgatgcgct gatcgaagca cgacaagcag
     5821 ttgaaatgac gaacttagct tcgcagattt tagaccagct ctctggcact tataataatt
     5881 tgctgaataa caacttgaat gacacgatga aatttttgac ggtctggtcg ctgatcttga
     5941 ccgttccaac tattgtgaca ggattcttcg gaatgaatct ccagttaccc tttacccatt
     6001 ccgttttcgg atggggaatc gccttgatca tcagtttggt cttatctatt tggatgctta
     6061 ttgcactgtg gcggcggatt cgttgatcta gtctttgatc tgcaaaccaa gggcttgggc
     6121 gatcacaagt gcttgctctt ggttgacgat tagtcccgcc aaagaatctt gagataaagc
     6181 gattgctgtg aagaaattag tcgtaaagtc taatcccttc agagaagttc gaaaccagtt
     6241 cgaaccggtc aactgattgt cagacaaaaa aaggtttttc caagtgacct cataaaattc
     6301 gctgtcttct aattgacaat gatcgaagga gacagctttc aagtttgtac tactaaagga
     6361 agccatcgaa gcaatacaat cagtgaaagt acagtctcga agataacttt cggcaaaatt
     6421 cgtacctgtt aatttacatt gatgaaacac gacttggtgg aaactgccac caatccactc
     6481 cagattggaa aaatcacatt tttcaaaaat gacattactg cattcaaaat gacgtaaaac
     6541 tgttttttgc atcgtaagtt tttggatatg actctctctt aataccatat ttttggcatc
     6601 gagatagctt tggtcacccc cgttgatcag aagaccagag aagatctcct catcttctaa
     6661 ataaaactct ccctttgtaa gaagaggaag agaaggtgga ataggttcga tttttttcat
     6721 gtgggttcac ctcgtttttc tttagtatag caaagaagcg ggaatcactg ctagaaagtc
     6781 tgctaatcta atcattttca gaaaaggaag acaaactgta tgaaaaacat tgacaaaaag
     6841 attagttttt gctatactgt gatggttgag aaataaaagc agaagcaccc gcttctcgcc
     6901 ttagttgata atgtcactgg gctagatagt tttcactggt tctattaggt gaagtacgcg
     6961 cgggttctgt aagagaactc gtttttttat tgccgtttat tcggtaagct tttctttctc
     7021 tcataatatt tggaggtgaa tgaccatagc aaaggatatg atggttaacg acggcattcg
     7081 tgcacgagag ttacgattga tcggttcaga tggtgagcaa ttaggagtta agacaaaagc
     7141 agaagcattg aatattgcag aacaagcaaa cttggatctt gtgttagttg cccctggtgc
     7201 gaaaccacca gttgcgcgaa tcatggacta cggtaaatac cgtttcgaac aacaaaagaa
     7261 agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta aaagaagttc gcttaagtcc
     7321 tacgatcgac ttgaatgact tcaatacaaa acttcgtaat gcacgtaagt tcttggaaaa
     7381 gggcgataaa gtgaaagctt ctatccgttt caaaggccgt gccattaccc ataaagaaat
     7441 tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg gatattgcaa cagtggaaca
     7501 aaaagcgaaa atggacggac gcagcatgtt cttgacgctg gcaccgaaaa acgacagtaa
     7561 gtaatttgaa tgactaactg gctgttggac agccgatagt cggataacga aagattttga
     7621 ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg gatcagcaaa acgtttcaaa
     7681 cgtactggta aaggcggatt gaaacgcttc cgcgcgttta caagtcaccg tttccacggc
     7741 aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca tggtttctag tggcgacttc
     7801 aaacgtattc gccaacaact agcaaaaatg aaataagaag tacaaataac agaatctgaa
     7861 gatttatttt tattaggagg aattatacat ggcacgtgtt aaaggtggaa cagtaactcg
     7921 taaacgtcgt aaaagagtgc taaaattagc aaaaggttac tacggttcaa aacacacttt
     7981 atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac tacgcatatc gcgatcgtcg
     8041 tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt atcaacgcag cagctcgtat
     8101 gaatggcttg agctactcaa aattaatgca cggtttgaaa gttgctgaaa tcgacatcaa
     8161 ccgtaaaatg ttagctgact tggctgttaa cgatgcagca gcatttactg cattggctga
     8221 ccaagcaaaa gaagctttgg ctaaataagc taaacaatta taaagaggaa agaagataac
     8281 gaaaagttat gttctttcct ctttttttat ttacaatcct ccatcaaatg aaacaggaca
     8341 ataacgtata agtctaaaat agcataatta aggtttttta attgaaaact gaacatttat
     8401 ggtcaccctt taatgaaagc gctaactaca taagttagaa tgagtttgac tgatatatta
     8461 gtttgcttat cagaaaaaca aaatggacgg aggaataaca tgagtgatat tattattggt
     8521 attttgttag ttatctcatt ctttttcatg gtctggtact gtgtaaaagg ctacaacttg
     8581 atggtcggct ttgccatcat ggctactgta tggatgggat tagcgctagt cggaaacacg
     8641 ttttcaccaa acccggcgat ggaagggcaa ggagtaattg atgtgttgac gcatatctat
     8701 acgacggggc cagctgagta cgccaaatcg atcttggtaa atgtcttctt tggtgccttt
     8761 ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc tgattcgaaa ggtagttgaa
     8821 cttggagggg acaagccaag aatcacgatg agcttactat gtattgtaac cgctgttata
     8881 ttcatgtcga tgacaggaat cggaccagtg atttctattg cagttattgt gttgccaatc
     8941 ttgatgtcat taggtatttc agtaccggtt gcactgttct catttatggg ctcgattatg
     9001 gctggaatct ttgctaatat cgtcaatttc aaacaatatc aaacgattta tgctggtttc
     9061 aatccagcgg ctgaaagcta tacttataat gactatttcc aaattggtat gattgggatg
     9121 attgtaagct tagttgtggt actaacggtc gctaatatat caatgaacaa aaagaaacgc
     9181 tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg caccaatgat ctcatggtta
     9241 gccgtattat taccagtttt aggggtcgtt cttttagatc ttccaatcat cttaggtttt
     9301 attctagcag gtatctgggc attgctgttt actggaaaat tgcgcggagg ttataaagaa
     9361 atctgtcgtc agtttgcgaa attatttaca gatggcgcag tagatgttgc gccaatggtt
     9421 ggtttcttga tgaccttagc gatgttcaat aattcagctg cgtatgcttc tccttatttt
     9481 tcagctattt ttggagattg gataccgcaa tcaccattag tcttggcaat cgtatttgct
     9541 atattgacac cactaggatt tttccgcggt ccaatgaatc tagtcggttc aggctcagct
     9601 attttagctg tcgtattagc tgttaatcca acgatgtcgc cagccttttt gttcccgtta
     9661 tttgcaatca caacgattgc tcctcagcat ttagatatta cacaatcttg ggttgcttgg
     9721 ggattaggtt atacaaaagt aacttctcga gaatatatga agaaatccat cccaactggt
     9781 tggatcatcg gagcgatctt atgcctgatc acgttcttat tgtacgggaa cgcctagtaa
     9841 acaaaacgtc gataaaaacg attagatgaa tggaggaaaa gaaaatgaaa cgttttgtgc
     9901 gaatgggaat tgatgttggc ggtacacata cgaaagcagt cgcaatcgat aatgcgacgc
     9961 acgaaatcat cggaaaatct tcagtgaaaa caacccacga tgatgtccgt ggagtagccg
    10021 caggtgtcgt tcagtctttt caaaattgtt tgctggaaaa taatatcagt ccagaagatg
    10081 ttgtgtttgt tgcacattct accacacaag cgactaatgc actgattgaa ggagacgtag
    10141 caaaagtcgg cgtaatcggg atggcaaaag gtggattaga aggtttttta gcaaaacgac
    10201 aaactagatt gaacgatatc gatttaggga ataagaaaaa aatagagatt gtcaatgcat
    10261 tcttacctgt caaacactta aatgtagacc gtgtttcaga aacgatttct tctttagaaa
    10321 gagaaagagc ggaggtcttg gtttcttcta tggcatttgg agtagataat ggggaaccag
    10381 aacgagttgt ttatgaagca gcatcggtaa aatcgatccc tacaacgatg gcttctgaca
    10441 tcacaaaatt atatggattg acaagaagaa ctcggacagc agcaatcaat gcatctattt
    10501 taccaaaaat gctagatacg gcaacctcta cagaagattc cgtacgagaa gcaggggtca
    10561 atgtttcttt gatgattatg cgcggagacg gcggagtaat ggaaatcaat gaaatgaaaa
    10621 aacgacctgt tttaaccatg ctttccggtc cagcagcatc agtcatgggc tctttgatgt
    10681 acttgagagc gtctaatggt gtttattttg aagtaggcgg aacaacaacc aatatcgggg
    10741 tcattaaaaa tggacgtcca gcaatcgatt attcaattgt aggtggccac ccaacatata
    10801 tctcttcatt agatgttcgg gttctaggtg tggcaggcgg ttcgatggta cgggctaatc
    10861 agtcaggaat catcgatgtc ggtccacgtt ctgcacatat tgccggtcta gattatgcag
    10921 tatttacgga gacagaaaaa atcaaaggtc ctaaggttga atttttctct cctaaagaag
    10981 gagaccctgc tgattacgtc aaggtagtga tggaagacgg agaagaagtg actattacaa
    11041 atacatgtgc agccaatgtc cttggattag tgcaagaaga acatttttct tatggaaatg
    11101 tcccatctgc acgaaaagcc atccaagcat tagctgatta ttgtcatacg acggttgaag
    11161 acatcgcaga acagatcatg gaaaaatcct atgctaagat tgaaccggtg attttagaat
    11221 tggcagacaa gtatcacttg gagaaagatc agatttctct tgtaggtgta gggggcggcg
    11281 ctgcctcatt gattacttac tttagtaata aaatgggtgt gaaatattcg attcctgaaa
    11341 acgccgaagt gatttcttct attggtgtag cacttgcaat ggtccgagat gttgtagaac
    11401 gtatcatccc ttcgccaagt aaagaagata tacgatcgtt gaaaaatgaa gcgatgaata
    11461 aagcgattga atcaggcgct acaccagaat cgatcgaagt ccacgtagaa atcgatccac
    11521 agacttcaaa agtaacggct atcgctactg gttctacgga agtgaaagca accgatctaa
    11581 ccaaggagat cacaacagaa gaagcactag agcttgctgc agaggatatg cgattaaata
    11641 aaaatgaagt ttgcttattg gaaaatacac ctttctttta tgtatgcggc gaacagaatc
    11701 gttcaaaaaa tgctggaagt cttcggatca tcgatcaaaa aggatttatc aaggtccaac
    11761 gtggacatgc ttcatgtatg aaaacaactg cagccaatta tatgacagct gtcgaacaac
    11821 tttgggaaga tatggcagtt tatcaaactg aattgattgc ccgaccagaa ttttatctct
    11881 gcttaggagc aagagtctct gattttacag cgacggatct ggaacaacta cagcttttga
    11941 tggatctgga agtatctact atggaaccgg aggaagaagt gatcgtcgtt gccggaaata
    12001 tcaaacaaac ataagttaga agagttacta aacgaattac aacagatccc cgaagaaatt
    12061 tggggattct accagtttcg gcgagattta ttttggaaaa agattccttt gtccaagcag
    12121 aaaattctta tacaacaatc aatcgattgt ggtatcgaaa cggcatgtag catcaaaaaa
    12181 aagtaccctt ttgccgatgt aggagaaatt tgtgaacaaa tggctgttcc aatcgtttcc
    12241 tgtgaatcag agcaaataaa cgaacgaatc acttttgcaa cttatgcaga agatgaaggg
    12301 attcgattga tgacggagcc gttagaaaaa ttaaaatgtt caggactagc ttcgatctct
    12361 aaagaaacag cgcaagcttt gattattgga catgaactat ttcaccacat cgaagcttct
    12421 gttaagggaa tttatacgca aagcgaaaaa attgtgctgt ggcggttgcc tttttataca
    12481 catcaatcaa acattcgtgc attgagcgag atagcagcga tgagtttttc aaaagagatg
    12541 aatcaaagcg atttttcgcc ttatgtatta gaggcagtct tactttggcc atataatgaa
    12601 attcgtagcc aagggatctt agaagaaata aaaaaaatag aaaaaagatg tacggagtat
    12661 gatttagatt acaaataaag agactgtgac aaaagtcgtg tcacagtcct ttttttccga
    12721 ataaacggtg ttctcctgtc aactcctcgg tcacaagtca aaatattcaa caaacatgag
    12781 aagctgtttt ttgaaattgt tccttgtgac tcggagatga acggcaggct cacgacctct
    12841 tggaaaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag ttaaaaacat
    12901 aagaagctat ttttacttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc
    12961 tctcaataaa cggtgtgcaa tcagctgacc ctcggtatta gctcaaaaaa aacggcaaaa
    13021 tatgaggaac tattttgccg tttctttctc taatactcag gtcaaaacgc tgattccaaa
    13081 acctcttatt tgatgggtct gtcctgaata tcttcaaaat aatcggggta attatgaatc
    13141 acgtattctt gctcctcgat aatcatatgt aaatgcatcg tgcaaagaaa tccgacttca
    13201 tcaaagttat gatcaatcat tgattgaagc attgtctgat gttcatctaa tactcgaccc
    13261 cagtctaatt ctgaaatcgt caaacgtaac catctgaaac ggttcaagtg cgtactataa
    13321 ctttctagcc aatcccaaat ttctcgtttt ccagcaattt cataacaagt tcggtgaaaa
    13381 tcagtatcca aatcaaaaaa agctttttta ttttgagcga ttactgcctg atcggtttgt
    13441 tctagtattt tttctagttt aacttgatct tgcttggtca ttttcgcact gcattcttgc
    13501 aggatcggtt tttccaactt ttcccgcgta taacgggcta atgaagcaga tcggatatcg
    13561 atttttgaaa cataagtgcc ggactgtgga atggttttta caagctcttg attgcgcagt
    13621 tggatcagtg cttctcgaat cggtgtacgc ccgatagcta gttgttcttc taacacttta
    13681 tcggagattt tacttccagg tgctaactcg gaataaatga tttgtttacg tatagattca
    13741 taagcttgct gttgcaaatt attgataacc atttaacctt cctttctatg cagatataat
    13801 ctattataac ataaatcgct tacaaatcgt gtgggcataa aaacacagtc tgcaaaaaaa
    13861 gccctgatag gcatgcctat tagagcctcg aaaagaaaaa tattgaatca atctggtcgt
    13921 acctcttgga tcggtttgac acgaccgccg attcttttag caaaagcttc ggattctttt
    13981 ttgtctttga aaatgagcag attgtctaag tttttttccc gagtgcgaca gccagtttta
    14041 tcgatgtaac cgtgcattac tttaacgaca tacatgggga tcacctgctt ttttcttttc
    14101 attatacgaa ctactcgaca caatacaaga aaaatgctta gacggtcttt attaagaatt
    14161 tacatcatcc aaagaagcgt acgcttggaa taactgatct aactccggat tgactttgct
    14221 cagcttcact aatcgttgcg aatcagaaag taaaaaacag tgtttactac tgccagtagt
    14281 ttttaatttt ttgtcttcag ttcccacaat ttcgtagcta aaatccaacc gtgtccccgt
    14341 atacttttgg atagttggat ggatgctcac tttttctccg taatggatca tttctttata
    14401 gctgcaattt acttccagaa cggggatgat gatcccagat tcttcgattt ttttataggg
    14461 aaaccctaga tgtaccaata aggctacccg agcctcttca aaccagcgga tataattgct
    14521 gtgatgaata atccccattt gatctgtttc ataataaaaa ggttctcgca cataacctgt
    14581 aaatttctcc atgactcatg cctcgttttc cattgatttt ttacaaaaat aattcatcca
    14641 tttcggaagt gcttcgctga tttgtgtcgg caaaacaata tattgttctt ttgccagctg
    14701 gtctccaatg aaactatgaa gataaatagc tgctgcaatc gtttggtcat tttgaggaaa
    14761 ctgggctaaa aatcctgtga tcatcccagc taaagtgtca cccatgccgc ccgttgccat
    14821 agcagcagaa cctaaaggat tggtgtagaa gtgctggtga ccataaattt ttgtctcatg
    14881 acttttcaaa acgagcacag caccgatttc ctgttgcttc tttttgtttt ctttatcccg
    14941 ttgttcttgt atcggtagag aactcaaccg ttgccactcc atttgatgag gtgtaagtac
    15001 agtttgttcg ggatagggta gcaaaagatg attagcagca agtaaactta aagcagagcc
    15061 atcaatcacc agccattgtt cttttgattg gttttctagt acttgtttga aacgttccaa
    15121 actcttagaa gaagtaccca atccgggacc aatcaagagt acatctgctt gctttattac
    15181 ggaaagaaac tggtcagtat ccgtccaaac tacaatcatt gcttctggca gatgactgtg
    15241 aagagcactc cgattttttt catcagttac tacagtcgtg agacccgctc cgctgtgtac
    15301 ggcagctaaa gcactcataa tgattgctcc gccatattgt tcattgccgc caatcaaaac
    15361 gatacgtcca aatgttcctt tatgtgaaat ttttggacga ggtgtgatga ctcttttcac
    15421 tagttgttcg tttatcagca tctaaaaacc tccttttact cattatagcg tatatttttt
    15481 ttagagaaaa acagataaga aaaggaattg tcagattttt tgaactattt ttttctgtaa
    15541 tttgtggtat catgaacacg aagacttaaa taagtggagg attaacttta tgacaattga
    15601 ttggcaaaaa gaagtagaag cacgtaaaga agacttgctt gaagacttga aaaatctttt
    15661 acgtgtcaac agcgagcgcg atgactcaaa agtaacacca gatgcaccat ttggacctgg
    15721 acctcgcgac gcattgaaac atatgttagc ttatggcgaa cgtgatggat ttaaagtaaa
    15781 aaatgtcgat aactatgcag ggcatattga tcttggcgaa ggagacgaaa cgctagggat
    15841 atttggacac atggatgtcg ttcctgcagg agatggctgg gacacagatc cttatgaacc
    15901 agtaatcaag gatggaaaga tctttgcacg cggatcaagc gatgacaaag gtccaagtat
    15961 ggcagcttac tatgcgatga agatcattaa agaacttgac ttgaaactat caaaaaaagt
    16021 tcgcttcgta gtcggcagcg atgaagaaag cggctggggc gatatggctt attatttcga
    16081 acatgaagaa gaaccagatt ttggtttctc accagatgct gaattcccaa tcatcaatgg
    16141 tgaaaaagga aatgtttctt tagctttacg cttcaaaggc gacaatgcag gagattatgt
    16201 cttgaaatct tttgtttccg gacttcgcga aaatatggtg ccaggaacag caactgcagc
    16261 acttcaagta ccaagtgcag atgcagctat cgcgatggaa gaagcatttt accaattcat
    16321 cgaagcaaat ccagtaagcg gaacgattga agcggacaat acgtatgtaa aaatcgaatt
    16381 agttggtaaa ggcgcacatg gtgcaagccc acaatctggt atcaatgcag gttctttctt
    16441 ggcattgttc ttagataact atgaattcct aggatctgct aaacaattta tccatgtagc
    16501 agctgcttat gtccatgaag atttttatgg agaaaaacta ggagtcgctt atgaagatga
    16561 aaaaatgggc aaattgacaa tgaatgctgg actatttgct tttgaagaaa atggtacaga
    16621 ggaagcgaac ttcatcaata tgaatttccg ttttccaaaa ggtgtaacag tagacggatt
    16681 gcaaagtgac atcgaacaaa cagtggggca agaaggcgca acagttactc gaggtgctcg
    16741 cgtaatggaa ccacattacg taccaatgga tgatccattg gtggctacat tattgcaagt
    16801 ctatgaagac cacactggag aaaaaggcta cgaacaaatc atcggtggcg gaacttacgg
    16861 acgtttgttg aaacgtggcg ttgcttatgg agcgatgttc ccaggatata ctgatacaat
    16921 gcatcaagca aacgaattta tgagtcttga tgacttgttc agagcaacag caatctatgc
    16981 agatgccatc tatcgtttgg cgaaataatt aattaaaaag aggatcaaga attgcaaatt
    17041 atttttgcag tcttgatcct ttttttactt tctactgtgg tattcatgat aaacatgata
    17101 tagattcaat tcatattctt tcttagcgtt cgtgacgact gtatccaaaa tcaaccctgt
    17161 tactaatgaa agaagtgcta aagtcatcaa tccagtactt aaaatcgcag aagggatgcg
    17221 tgtaataaag cttgtcagca tatattcgcg aatcacagga atccccgtga ccaatccaaa
    17281 taaaaagaag aagatggtcc aaatcccaaa gaaaagcaaa ggcttataat ctttaaacat
    17341 tttaataatc atcatgatca ctttgaatcc gtcagagaat gtattcaatt ttgattcgct
    17401 gccttcagga cgatcacgat aatcgattgg gatttcaacg aacttgaatt ttttatctaa
    17461 agcatggatc gtcaattccg tttcgatttg aaaaccagaa ctcataatag gaaaactttt
    17521 gacaaagata cgattgaatc ctcgatagcc ggtcatgaca tcaagaattt ttgttttata
    17581 cattctagta attgtatttc taacaaggtt atttccaaaa tcgtggaaag gtctcttatt
    17641 ctcatcaaag taggttccat ttgataggcg atcaccaatg accatatctg cttcaccaga
    17701 acgtaatttc tcgagcaaac catgtacagc ttctgcagga taagtatcat cgccatctac
    17761 cattaaataa tagtcggcat cgatatcaaa gaacatttgg cggatcacat ttccttttcc
    17821 ttgacgaggt tcttttttta cgattgctcc accttgaacg gccaattcgt atgttcgatc
    17881 ggtcgaatta ttatcataga cataaatatc tgcttctggt aattctcgtt taaagtctgc
    17941 aatgactgtt gaaattgttg cttcctcatt gtaacaagga atcagaacag caattttttc
    18001 ttgttgttcc atttttcact ctccttaact atagaaaaca aaagctaaat taaaaatacc
    18061 tcataatcaa aggaaatgct agtttttccc gctaaatatc atttatttaa aaagaaaata
    18121 ctggaatata tgtttggaaa gctctatcta aaaaaccacc cactacaaaa gaaggacatg
    18181 atacctctct tttgaatagt gggtgcgtat tcgttctctc acttttttga cgtattaatc
    18241 tgttgcacct ttttttcttg aaatttctaa tacggttcct gtatgagcat ctgctaaaaa
    18301 ttcataataa acagtttcgc catcttctat tcgagaaaga cctccccgat aagcactcga
    18361 ccgaacggcg aatttcctaa taggttcctt ttcaaaagag atccaagaac cttcgattgc
    18421 accttctttt agaaaagatg acttgatatt ttcaagtact tggtctgctg acaatacttt
    18481 tttgcgatga taccaaatcg ttgaagctac cccgctcaat aatcctagac cgattccaac
    18541 tgctaacccg cctttaaaat agcttagttc gctttcttca tacatgtgga catacctcct
    18601 tcttctcact tgttactcct tgtgcttatt ttaccacact ctcatatttt ctttgaaata
    18661 aataaccgct accagaaaaa ataagctata ataaatacga tcggtctgca gaaaaaatca
    18721 tattttatcc gcagatcaat ataagtctga gaggagttta gtctgaaatt tagacgaata
    18781 gcatatggaa gaaaaaacat ttcaacgaat caaagagtta acagaattac aaggaacaag
    18841 cggttttgaa caagatgttc gcgcttatat ggaaagtcat atggaaccgc tggtagatga
    18901 gttacagtta gatggtttgg gcggcatttt tggtctgcgc catcatgaag aagcggatgc
    18961 accccgtgta atggtcgcag cacatatgga tgaagtcgga ttcatgctga cacaaatcca
    19021 agaaaacggg ctttttaaag tcgtacctct aggcggctgg aatccttacg ttgtttctgc
    19081 tcagcgtttt acacttaaaa cctctactgg taagaattat ccatgtattt cttcttccgt
    19141 tcccccacat ttattgcgag gaacaagcgg acaaaaatca gtagaagtaa ccgatatttt
    19201 gttcgatgct gggtttgaat caagagaaga ggcaatgagt tacggtgtcc ttccaggaga
    19261 cacaatcgtt ccttacgctg aaacgatcaa aacagccaac ggaaagaata ttatcagtaa
    19321 atcatgggac aaccgctatg gctgtacaat ggtattagaa gctttagaag cgttgcaaaa
    19381 tgaaacatta ggtcatacat tgattgcagg cgcgaatgtc caggaagaag taggcttgcg
    19441 tggttctaaa gcttctgtca ataaattcaa gccagatctg ttctttgcag tagactgctc
    19501 tgcagcagat gatacagtga cgaaaaatgg cacattcgga catttaggag aaggtacatt
    19561 gatgcgtatc caagatccag gtttgatcat gcttcctcgt ttgcgcgagt acttgctgga
    19621 tatcgctgaa acaaacaata tcccttatca atactttgtt tcaaaaggcg gtacagatgc
    19681 aggtgctgct catacacaaa acgaaggaat cccaagtaca gtgattggcg tagtgggacg
    19741 ttatatccat acgcatcaaa cgatgttcag tattcgcgat tttgaagctg cacgagaaat
    19801 gttgattcaa acactgaaag gtttggataa atcaacagta aatacgatcg tatacggaaa
    19861 ataatgcgat agtgaaacta taaaatctgg caaaagattg ctttttgcca gatttttttt
    19921 ataaaaagag gatcaatgtt tgttagttcg aaagaaaggt gtataattta attgaaaaat
    19981 acataaacag aaagtagagg acaaagaatg attatcccaa atagtttaga agaattagca
    20041 ggctacgtag aaactggaaa gagtgtattt ttctttactg ccggctggtg cggagactgc
    20101 cgttttatca aaccgcaaat gcctgaaatt gaaaatgact tttctgattg gcaatttatt
    20161 gaagtagacc gtgacaagta catagatgta gccgctgaat ggaacatttt tggtatccca
    20221 agttttgtcg tgatccaaga cggaaaagaa ttaggtcgtc tagtgaataa agatcgtaaa
    20281 acaaaacagg aaatcgaatc gttcctagaa agtgtaacaa aaggctgaca tctgttagga
    20341 ggggtcaaga tgaatcaaga atataagaat attttagtag gtatcgacgg tagtgaacaa
    20401 gcacttgctg ctttcaaaaa agcggtagaa gtggctcgcc gtaataatgg gaaagtatat
    20461 gtagcaaacg taatcgatca gcaattttat aactttatgg gctatgcacc tattgatcaa
    20521 aatctagtcg atcagcaaac tgaaacagcc aaggaaatga tcgaagaatg taaagaatat
    20581 gggaaatctg ttgattacac aaatatagaa ggaattattg catatggttc tgttcgtgaa
    20641 tccatggcag tcaaattgcc aaaaaaatat gagatcgatc taatcatggt tgggcagtca
    20701 ggtctaaatg cagtcgaacg ctttatgaca ggaagtgtag ccagctacgt gatacgtcat
    20761 tcaccttgtg atgtcttgat cgtttctgac gaagaagaac agccaagtaa ttaagcaagt
    20821 ggaacttgta cgaccttttt aatcaattaa ctaaaacagt aaagggactg tgacaaaagt
    20881 cttgtcacag tcccttgtta cgaataaatg gtgttccaga agaggcttct tcggaaataa
    20941 agcatgaaaa aaatttcatg cagtgaatgc aattttttgt taagataaat ctcagcaaag
    21001 gataatggag gaaagaacat gatttttgct tataacaaag cacacgtcgg agacaccttg
    21061 atggttatta tagccgacga taaaggaaca gaaaacactg ttgaacgcaa atggaatgtt
    21121 gctcggatca aagatgaaca aggtcaagtt gttgcttgga actttttcca tatctccgat
    21181 catctaacaa tcgaagggaa cggccaagta agcttaacag atgaggaatt agcgaaattg
    21241 aatcgattga tcaaagaagc aggattcgaa gaacagcttg aagctgatca tgaaccgaag
    21301 atcgttgtcg ggtacgtaaa aacatgcgtc ccacatcctg attctgacca tttatcgatt
    21361 actgagacag aagtagacaa tggtacagta ttgcaaatcg tttgcggtgc acccaatatc
    21421 gaagctggac aaaaagttgt cgttgcaaaa ccaggagcta tgatgccaga tggaatgatg
    21481 atctggccag gaactttgcg aggggtagat agctatggaa tgatctgttc cgctcgtgaa
    21541 ttgcatttgc caaatgctcc agcaaaaaaa ggaatcttag tattgcctga ggatgccgta
    21601 gtcggagaag catttccaaa ataaagaggt tgtgacaagt ctttgtcaca acctcttttt
    21661 tattaatttt cactattttg attttgtttt aatgccgatt gatcgatcgt caattcaaca
    21721 gtagttgttt tttctttcga gccttcatag taagtgattt tgacagaatc tcccactttt
    21781 ttcttataca aagcagattg aagttctaca ccagaagaaa cttctttgtc atcgatctta
    21841 gtaatgacgt cgtattgttt caatccagct ttttcagccg gtgtagctgt ttggacattt
    21901 gtcacgatga caccgttagt tacagatgaa ggaatcttca agatttgttc ttgttgctga
    21961 gtagaaacgg cagataagtc gaccattgtg atacctagag ctggacgtgt cacttttccg
    22021 tctttttcca gttgattgat gatattcact acatcgttac ttggaatagc aaatcccatt
    22081 ccttctacgc ttacattaga agtagattca gaagtacttg cgatcttact tgagttgata
    22141 ccgataactt gtccttcgat attaactaaa ggaccaccag aatttccagg gttgattgct
    22201 gcatctgttt ggatcgcatt gatattgact gtttcgttcg attcattcgt acttgtcact
    22261 tgtcggttca aggaagaaat gattcctgaa gtgacagaat ttgcatattc agatcctagt
    22321 ggggaaccaa tcgcaatcgc aggctcacca accttcagag cacttgagtc accaaaagag
    22381 gcaactgttt cgactttgtc tgaattgatc ttcaacaccg ctaaatctga ataagcatct
    22441 gttccaacta attcagcttt taccttcgta ccgtctttca tcaagacttc aagaccttgc
    22501 tggccatcta ctacgtgatt attcgtgact acataagcag tattcccgtc ttttttgtag
    22561 atcacgccgc ttccttcact ataagcttcc aaattactat catctgagct gctactttct
    22621 tcttgctgcc cgaatagtcc gccaaaaccg cttgattggt tttgactttg taagttgata
    22681 acagaaacga cagcgtcttg aactttatct accgctttgg tgatatcaga atctacattg
    22741 actttgacat tttccacaac tgtttcaccg gcagaattct gattgccgct tgtagcagta
    22801 gaactattgt tgccagtgcc catcgctgca taaaaaatgc cagctgtcag tagtcctcca
    22861 acgatccctc caacaagccc cagacccaac ttacgccaga ggctattatt tttatttttt
    22921 ttcatctttg gtgtcacatt ttttctatcc atgtgttcct cctccaatta cattcattta
    22981 tctactgtta gtatagtctt atttgttgac tttagtctac tttgagactt tgaacttttt
    23041 atgaaaaact ttaggaaaaa tcattgtttt cagatgaaaa tatttgattt tctttttcca
    23101 cagatattgt gtaaaactac gcggatagga ttggaaaaat aagggataaa acatatccac
    23161 agcctgtgta taaagtggat aaattcttat aaaacgtatg tttgcctaat gaatgtgatg
    23221 aaataaggta aaacaacgct gttttctgtg gataaacctg tggatgttgt gcataactgt
    23281 tggggaaatc tttttaacaa aaatagtcaa aataaacata tagacgaaaa aattgattat
    23341 aataaacaaa gtgagcgtga agatcaaagg agagaaaaca tgaatatcaa aattatttca
    23401 gtaggaaaat taaaagaaaa atacttgatc caaggtatca atgagtatgt caaacggctg
    23461 aatgcctatg cgaaaatcga attgatcgaa gttcctgacg aaaaagcccc ggagaattta
    23521 agcgaagcgc aaatgagaca agtaaaagaa aaagaaggag aacggatctt agcgaaaatc
    23581 aaagaacaag aatacgtcta tggcttagca attgaaggga aaaatcccac aagcgaatct
    23641 tttgctaaac aaatcgacca attaggtatc caaggaaaaa gccaccttgt ttttgttatc
    23701 ggcggttctt taggactcag cgaagccgtc atgaaaagaa gcaatgctca gatctctttt
    23761 ggcaaaatga cgtatccaca tcaattgatg cgcctgatcc tcgtcgagca aatctaccgt
    23821 gccttccgga tcaacgcggg ggctccatac cacaaataat gatatttttt aagagaaaaa
    23881 tagcataaaa atctagttat ccgcataaaa actggactta tcacacttta tcaaggtcaa
    23941 aaccactcaa tttactacta atttactact tatgaatgag ctttgatacg acgatttatc
    24001 cttgaaaagt gaagatataa agatacttcc aataaaattt gaatatttaa taggtagaca
    24061 cttcaaaaaa tgaggtgtct atttttttac ccgattttga aaggaagtga acttatgaaa
    24121 acaaaaaatc aagaatcaaa aggtcgttcc ccactcttta agaccatcaa acattcattc
    24181 agccaataaa aaagaaagga taggtaaaaa tatggaactt aaatttgtga ttcccaacat
    24241 ggaaaaaaca ttcggcaatt tagaatttgc tggcgaggat aaagtcgttc agcgaagaat
    24301 caacggacgg ctaactgtct tatcaagaag ctataatctc tattctgatg ttcaaagagc
    24361 agatgatatt gtggtggtgc ttcctgctga agctggcgaa aaacatttcg gctttgagga
    24421 acgtgtgaag ttagtcaatc cacgtattac cgcagagggc tacaaaatcg gcactcgtgg
    24481 ttttacaaat taccttttac atgctgacga catgataaaa gaataaagaa agagaggaaa
    24541 aatgatgaga ttagcaaatg gcattgtatt agataaagac acgacttttg gagaattgaa
    24601 attctctgct ctacgtcgtg aagtgagaat ccaaaatgaa gacgggtcgg tttcagatga
    24661 aatcaaggaa cgtacctatg acttaaaatc caaaggacaa ggacgcatga ttcaagtaag
    24721 tattcctgcc agcgtgcctt tgaaagagtt tgattataac gcacgggtgg aacttatcaa
    24781 tcccattgcg gacaccgttg ctactgccac ctatcaagga gcagatgttg actggtatat
    24841 caaggcagac gatattgtgc tgacaaagga ttctagttca ttcaaagctc aaccacaagc
    24901 aaagaaagaa ccgacacaag acaaatagtc gctaggtaga aaggagactt tttcgcatga
    24961 aacagcgtgg taaaaggatt cgcccatctg gtaaagattt agtctttcat tttacgatag
    25021 cgtcactcct gcctgttttc ctgctggttg tcggactgtt tcatgtgaag acaatccagc
    25081 agatcaactg gcaggatttt aacctatcac aagcagataa gattgacatt ccctatttaa
    25141 ttatcagttt cagtgtcgca attcttatct gcttgctggt agcgtttgta ttcaaacggg
    25201 ttcgctatga tacggttaaa caactttacc accgtcaaaa actggcaaag atgatacttg
    25261 aaaacaagtg gtatgaatct gaacaggtca aaacagaggg tttctttaaa gatagtgctg
    25321 gtcgtacaaa ggaaaagata acctacttcc ctaaaatgta ttatcgactt aaaaatggct
    25381 tgatacagat acgggtggaa atcacgctgg gaaaatatca agaccaactc ttacacttgg
    25441 aaaagaaatt agagagtggc ttgtactgtg agctgacgga taaagagtta aaggattcct
    25501 atgtggaata tactttgctc tatgacacca tagccagtcg tatttctatt gatgaagtag
    25561 aagctaaaga tggtaaactt cgcttaatga aaaacgtatg gtgggaatat gataagctcc
    25621 ctcatatgtt gattgctggt ggtacaggtg gcggtaaaac ttactttata ctgacactga
    25681 ttgaagcctt gcttcataca gattcaaaac tgtatattct tgacccgaaa aatgctgatc
    25741 ttgcggactt aggttctgtg atggcaaatg tctactatag aaaagaagac ttgctttctt
    25801 gcattgaaac attctatgaa gaaatgatga aacgtagtga ggaaatgaag cagatgaaga
    25861 actataagac tggcaaaaat tatgcttact taggtctccc ggcacacttc ttaatctttg
    25921 atgaatacgt cgctttcatg gaaatgctgg gaacaaaaga aaacaccgca gttatgaata
    25981 agctgaaaca gattgtcatg ttaggtcgtc aagctggctt ctttctaata ctggcttgtc
    26041 aacgtccaga cgcaaaatat ttaggcgacg gaatccgtga tcagtttaat ttcagagtgg
    26101 ctttaggtcg tatgtctgaa atgggctatg gcatgatgtt tggcagtgac gtacaaaagg
    26161 atttcttctt aaagcgaatc aaaggtcgtg gctatgttga tgtaggaaca agtgtcatat
    26221 cagagtttta tactcccctt gtaccaaaag gatatgattt cttggaggaa attaaaaagt
    26281 tatccaacag cagacagtcc acgcaggcga cgtgcgaagc ggaagtcgca ggtgtggact
    26341 gatcttgctg gctggtgtgg caatagccac gccagcactt aacccctcgg tatctaacag
    26401 gggggtacaa atcgacagga aacagtcaaa aaaacattag aaaatccttt ggttacaagg
    26461 gatttacaaa atttcagcgt atgtcaaatg ggctttaaaa gttgacatac gcctttttga
    26521 ttggagggat ttttactgaa tgaacaaact tggttacagc atttaaaaga aaaacgcttg
    26581 gcttatggac tatctcaaaa ccgtttagct gttgcgactg gtattacaag gcagtatcta
    26641 agcgatattg aaacaggaaa agtcaagcca tcagaggatt tacagcagtc cctttgggaa
    26701 gctctggaac gcttcaatcc cgacgctccc cttgaaatgc tgtttgatta tgtaagaatt
    26761 cgctttccga caacagacgt acagcaggtg gtcgaaaaca tcttacaact gaaactgtcc
    26821 tattttcttc atgaggacta tggtttctat tcttattcag agcattatgc tttaggcgac
    26881 atattcgtcc tttgctccca tgaactggac aaaggagttc tggtggaatt gaaaggtcgt
    26941 gggtgcagac aatttgaaag ctatcttctg gcacaacaaa gaagctggta tgagttcttt
    27001 atggacgttt tggtggctgg cggtgtgatg aaacgccttg accttgccat taacgataag
    27061 acagggattt taaatatccc tgtactcact gaaaagtgcc aacaggaaga atgtatctcc
    27121 gtcttccgca gttttaaaag ctatcgcagt ggcgaactgg tacgcaaaga ggaaaaggaa
    27181 tgtatgggaa acaccctcta tatcggttca ttacaaagtg aagtttattt ctgtatctat
    27241 gaaaaggact acgagcagta caagaaaaat gatattccca ttgaagacgc agaagtaaaa
    27301 aaccgttttg agattcgatt gaaaaatgag cgtgcctatt atgcagtccg tgatttactc
    27361 gtctatgaca atccagagca taccgccttt aaaattatca atcggtatat ccgttttgta
    27421 gataaagacg attccaaacc tcgttctgat tggaaactga atgaagaatg ggcttggttt
    27481 attgggaaca atcgtgaacg attaaaacta accacaaaac cagagcctta ctccttccaa
    27541 aggacgctga actggctatc tcatcaagtt gccccgacct taaaggttgc gattaaactt
    27601 gatgaaatca accagacgca ggttgtaaaa gacattctcg accatgcgaa actgacagac
    27661 cgacacaagc agattttgaa gcaacagtca gtaaaagaac aggacgtgat aacaacaaaa
    27721 aaataactca aatacaaatt cattgaatat agagaggaga acatttttat gaattttgga
    27781 caaaacct
//
LOCUS       DACGLI010000041        27120 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.042, whole genome shotgun sequence.
ACCESSION   DACGLI010000041 DACGLI010000000
VERSION     DACGLI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.042"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            2..74
                     /locus_tag="IXT22_001897"
     tRNA            2..74
                     /locus_tag="IXT22_001897"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="IXT22_001898"
     tRNA            78..150
                     /locus_tag="IXT22_001898"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="IXT22_001899"
     tRNA            155..225
                     /locus_tag="IXT22_001899"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="IXT22_001900"
     tRNA            238..311
                     /locus_tag="IXT22_001900"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="IXT22_001901"
     tRNA            323..394
                     /locus_tag="IXT22_001901"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     gene            660..1853
                     /locus_tag="IXT22_001902"
     CDS             660..1853
                     /locus_tag="IXT22_001902"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAQ4863246.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="IXT22_001903"
     CDS             1983..3455
                     /locus_tag="IXT22_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863247.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="IXT22_001904"
     CDS             3538..4326
                     /locus_tag="IXT22_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAQ4863248.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="IXT22_001905"
     CDS             complement(4393..5061)
                     /locus_tag="IXT22_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4863249.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="IXT22_001906"
     CDS             5176..6888
                     /locus_tag="IXT22_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863250.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8660
                     /locus_tag="IXT22_001907"
     CDS             6891..8660
                     /locus_tag="IXT22_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863251.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(8865..9431)
                     /locus_tag="IXT22_001908"
     CDS             complement(8865..9431)
                     /locus_tag="IXT22_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4863252.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(9431..10387)
                     /locus_tag="IXT22_001909"
     CDS             complement(9431..10387)
                     /locus_tag="IXT22_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAQ4863253.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(10387..11043)
                     /locus_tag="IXT22_001910"
     CDS             complement(10387..11043)
                     /locus_tag="IXT22_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4863254.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            11413..13431
                     /locus_tag="IXT22_001911"
     CDS             11413..13431
                     /locus_tag="IXT22_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4863255.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            13858..16272
                     /locus_tag="IXT22_001912"
     CDS             13858..16272
                     /locus_tag="IXT22_001912"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAQ4863256.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            16620..18173
                     /locus_tag="IXT22_001913"
     CDS             16620..18173
                     /locus_tag="IXT22_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4863257.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(18554..20338)
                     /locus_tag="IXT22_001914"
     CDS             complement(18554..20338)
                     /locus_tag="IXT22_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863258.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(20353..22074)
                     /locus_tag="IXT22_001915"
     CDS             complement(20353..22074)
                     /locus_tag="IXT22_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863259.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            22174..22935
                     /locus_tag="IXT22_001916"
     CDS             22174..22935
                     /locus_tag="IXT22_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4863260.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            23902..24170
                     /locus_tag="IXT22_001917"
                     /pseudo
     CDS             23902..24170
                     /locus_tag="IXT22_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            24842..>27120
                     /locus_tag="IXT22_001918"
     CDS             24842..>27120
                     /locus_tag="IXT22_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863261.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAP"
BASE COUNT         8666 a         4772 c         5666 g         8016 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattatttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaactgt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcacgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaataa agaggttgtg aaaaagctgt cctgcatcaa gtaataagaa
     8701 cagccaatca aaaacagctt ctcatgtttt tgatttggtt ggacttatta ccgcagatat
     8761 aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa cgctctaacc tgagtattag
     8821 agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt ttatttatct ttttttctca
     8881 atacaatata aaataggcgg ctggttcttt tggttgataa accgataatt cagcacatta
     8941 tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca tatccagttc tttttctcca
     9001 ccttcatgac catagtagac gacaaggatc aatcgtccgc gaggcacaag tcgtttcaat
     9061 atttcttcca tagctgtgcg tgtagtctct ggcatagtga tgattgcttt atcacttttt
     9121 gggagatacc ctagattgaa aatccctgct ttgagatttt gttgttcagc tatcacttct
     9181 cctaacgttt cgtggccttg tagaaacaat gagacacgtt cttctaactg acgctgttct
     9241 agcctttcac gagtagcatc gattgcttgt tgctggatat caaaactata gacatgacca
     9301 gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc cattgcccat cgttgcatct
     9361 acgacgtgat cccctggttg caagatttct tgcagtaatg tatggctgaa atgcaaagca
     9421 gtttgcaaca tcagacgctc acctttttcc gtacatcata ttttccttgg aagctatctc
     9481 tgcgaagaag ttcttcatca attgcattca agacttccca ttttttcaag ctccacattg
     9541 gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg atggatgatg atctcttttg
     9601 gtatcatttc cagctggtcg caaatgacat tgacatagtc aggacggctc attaattgaa
     9661 ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg catcagatgc atcaaatgga
     9721 gcttgattcc ttggatatct gaatctaaaa tggtgcgtct gacattttct ttcatcattt
     9781 ctaaactttc gcctggtaat ccgttgatca aatgcgtaca aacacggata ttatgtttgc
     9841 gtaatttagc cacgccatct aaataagttt gataatcatg tgctcggttg atcagttttg
     9901 aagtttcttc aaaagttgtt tgcaatccaa gttctaccca taaatacatc cgctcgttca
     9961 gttcagcaag gtaatcaact acttcatctg gcagacaatc cggtcgtgta ccgactgata
    10021 atcctacgac acctggtaaa ttgactactt gctcaaatcg ttctttgatt atttcaactg
    10081 gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta ttgttggaca tgaggccatt
    10141 tttgatgcat catgtcgatt tctttctgga attggattgg aagagggtct tcaggtgcaa
    10201 cgatcatgtc tcccgaacca gatacactgc aaaaagtaca accgccatgg gcaacagtcc
    10261 catctcgatt cggacagtca aatcctccat cgatcggcac cttgaaaatt ttcccgccaa
    10321 actcatttcg taaagcgtaa ttccaagaat gatatctttt atttccttct gaataaggaa
    10381 aagtcattaa aagtccttct ttctgtaaga gttatctatt tgttttcttt tttctctata
    10441 cactggataa gtcaggcaca gccaagaaag actgagtaag taaccgccga tgatatcagt
    10501 aggaaaatga acgcccagat aaatgcggct tatcccgaca cttactataa taaacatcat
    10561 cagcaattga agcaatgtgc gtaaggttct tttttgaaca aaagctggaa gcagaaatag
    10621 taaagaaccg taaagaatca tactgcctgc tgcatgtcca ctagggaaac tgtaacttgt
    10681 ttcaactact aagtgcgcca atgaaggacg ctctcgcatg aaaaatagtt tgatcaccgg
    10741 gttgatgatt ccagcaatta caataaatcc agaaacgaac caaaatgttt ctgccctttt
    10801 tttcttatac cacatccata aagccgcaca agcaaataaa atgatgacgg taagaggatt
    10861 accgaattta gtcataaaga gttggtagct gttcagatca ggataagaag ctctgacaat
    10921 gcctgtaaac cactgatcga aaccagaaag ccacgacaga tggaacttta cgatccagcc
    10981 caaaatgaaa aacaggacaa gaaagaagct accagccacc tgaaatgatg ttttatattt
    11041 catacaattc ctcctttgaa gcaatgactt attatagcat ttttggtcca gcgaaaaaaa
    11101 cggtaaagag ataaaaccaa tgtatgattc ctctttgaat aaccaatatt cttataaaaa
    11161 aaataactgt aatcggaaag acattttttg gtaatgcaaa tgaaatgtta gggaaataaa
    11221 atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac gtaggaagaa cttgaaaatg
    11281 aacagaagtt gttcattacg gtaaattaca atatgattac aaaaaacaac aaagctctta
    11341 aataactttt aataaatatt aagagaagtt ataattatta ataatagata aattgaagtt
    11401 ggaggataga agatggaaaa cattgcaaga aaagaacgga gacgtttaga acagaccaaa
    11461 cgttttcgaa aagcaaaacg aggggcagca atcgtgggaa ctgcgatggt aggctgttct
    11521 gtcgctgccc cattagtaca gccggttcct gttcaagcgg atgaaacacc tgttcagttc
    11581 ggcgcaagaa tcaatacagc ggcatttatc acagaaattg ctacttatgc tcaaccaatc
    11641 gctcaagcca acgatctata tgcatcagtg atgatcgcac aagcagttgt agaaagcggt
    11701 tggggcagta gtgcgttatc tcaagcacct tattataatc tttttgggat aaaaggcagc
    11761 tatcaaggac aaaccgtcta catggatacg cttgaatttt taaataatca atgggtaaat
    11821 aaaaaggagc ctttccgaca atatccttct tttgctgaat ctttcaatga caatgcctat
    11881 gtacttagaa atacttcatt tggcaacggt tattactatg ccggtacttg gaagagcaac
    11941 acgaaatcct atacagatgc gacagcttgt ttgacagggc gttatgcgac tgatcctggt
    12001 tacgcaggca aattaaataa tatcatcgca acttacggat tgacccaata tgatacacca
    12061 gctagcggaa acgcaggcgg tggagcgact acaggtggca ataatactgg aagtgcaggt
    12121 agtactggcg gttcaagcaa ttctggtaat acaaactcag gttcagcaac ttcgaccact
    12181 tatactgtcc aatctggtga ttctgtttgg ggaatctcaa ataaattcgg tatcacaatg
    12241 gatcaattga tccaatggaa caacatccaa aacaatttca tttatccagg acaaaaactg
    12301 acaatcaaag gtagccagga aaatggctct tcgacgaata attccggtaa caataccaat
    12361 tcttcaggaa atgctggtac atcaaacgga ggacaaacaa ctggtgcgaa atacactgtt
    12421 caatctggtg attctgtttg gaagatctca aatgatcacg gaattacgat ggctcaattg
    12481 attgaatgga acaatatcaa gaacaatttc gtttatccag gacaacagct aatcgtatca
    12541 aatggcggtt cttctaatgc tggagcaaat actggctcaa atactgggaa tacaagtggc
    12601 tctagttcgt ccagctcaag ttcttctaat acagcttcag gaacgaaata tacagttaaa
    12661 gccggagact ctgtttggag cgtctcaaat aaatacggaa ttacgatggc tcagctaatc
    12721 caatggaaca atatccaaaa taactttatc tacccaggac aacaactgac tgtttcaaac
    12781 agtggatcaa caaacagcac gtcaggtaat acaggttcgt caaccaatac aaataacagc
    12841 agttcagtta atactggcag cagttcgtct caaggcactt ataccgtgaa agcaggtgaa
    12901 tctgtttgga gcgtggcaaa taaaaacggc atcacgatgg atcagttaat cgaatggaat
    12961 aatatcaaaa acaacttcat ttatccagga cagcaattga tcgttaaagg tggaacttcg
    13021 gcaaatacaa atacaggttc aactacttct gcagcgaaac caaatacacc gaatacgtct
    13081 gctacgacaa gtacatcatc cactggtaat acgatgtata ccgtgaaagc gggcgagtca
    13141 gtttggagcg tagcgaacaa acatcatatc acgatggatc agttaatcga atggaataat
    13201 atcaaaaata atttcatcta tccaggacag caagtgattg tgaagaaagg ttcatctcaa
    13261 tcaacaaacc aacaatcagt tactggttcg aaaacctata ctgtgaaatc tggagaatct
    13321 gtttggagtg ttgctgacag tcatggaatt acaatggctc aactaatcga atggaacaat
    13381 attaagaaca actttattta tccaggtcaa acgttgattg tagctaaata aaatagctgt
    13441 tcgaagaaat aacgattgaa ttccacaaaa atatttgtta ctataaggct acttaaatat
    13501 gacaacactt gaaaaggaag tagtaaaaag actgaagttt cagagagcgc atggctggtg
    13561 agaatgtgca cggatgcttt tgaactcgcc tttgagttgc ccttgctgaa tacccgagta
    13621 agcaagcggc ggtgacggcc gttacaacgt tcgaggcctt ttcactaagg taaaattagg
    13681 tggtaccgcg tagattacgt cctataaaaa gagcaatctt tttataggat ttttttattt
    13741 cttttgtgaa gtttgagaaa acaaagcaaa aggaaataaa aataaacaga ttctgccggt
    13801 tttttcgtta tatttataat agaaacaagt gttttcaata gaacaggagg acagcaaatg
    13861 agttacaatc ataaagaaat tgagaaaaaa tggcaaaaat actgggcaaa aacgaatact
    13921 ttcaacaccc atgatgatcc tgaaaagcca aaattttacg cactggatat gtttccctat
    13981 ccatccggtc aagggctaca tgtagggcat cctgaaggtt atacggcaac ggatatcctt
    14041 tcacgtgtga aaagaagtca aggatacaac gtgctgcatc caatggggtg ggatgcattc
    14101 ggtctgcctg ctgaacaata tgcgctagat acaggaaacg atccagctga gtttacccaa
    14161 aaaaatatcg aaacattccg acgccaaatc aattctttag gatttagtta tgactggaat
    14221 cgcgaagtga atacaactga tccggagtat tataaatgga cacaatggat ctttacgaag
    14281 ctttatgaaa aaggtctagc ttatgaagca gaagtagcgg taaactgggt acctgaatta
    14341 ggaacagtta tttcaaatga agaagtgatc gatgggaaaa gtgaacgtgg tggctatgat
    14401 gtagtcagaa aaccaatgcg ccaatggatg ctgaaaatca ctgcttatgc tgatcgctta
    14461 ttggatgatc tagaattagt tgattggcca gaaagcatta aagaaatgca aagaaattgg
    14521 atcggtcgtt cagtaggagc aaatattgaa tttaaagtgg ctggtacgga taaatcctat
    14581 accgtattta cgacacgacc agatactcta ttcggtgcaa cttactcggt tcttgcacct
    14641 gaactagatc ttgttagaga aattacgacc cctgaacaaa aagctgctgt agaagcttat
    14701 atcgaagaga cagctaaaaa atcagatcta aagagaacgg atcttgcaaa agaaaaaaca
    14761 ggagtattta ctggtgctta tgcaatcaat ccagttaatg gcaaggaaat cccaatctgg
    14821 atcgccgatt atgtattatc ttcatacggc acaggagcca tcatggctgt tccagcacat
    14881 gatgaacgtg actttgaatt cgctcaaact ttcggactag aaattcttcc agttatcgaa
    14941 ggtggagatg ttgaaaaagc tgcttacaca gaagatggta cgcacatcaa ctctgaattt
    15001 ctagacggca tgaacaaaca agaagcaatc gataaaatga atgaatggct agaagaaaat
    15061 ggcgtaggga aaaaagaagt cagctatcgc ttacgtgact ggctattctc ccgtcaacgt
    15121 tactggggtg aaccaatccc aatcatccat tgggaggacg gaacagtcac agctgtccca
    15181 gaagaagagc taccattacg gttgcctaag acaaaaaaca tcaagccaag cggtactgga
    15241 gaatctccat tagcaaatat cgaggagtgg gtcaatgtcg ttgatcctgt aacaggtaaa
    15301 aaaggccgtc gcgaaacgaa tacaatgcca caatgggcag gaagctcatg gtattacctg
    15361 cgttatatcg accctcataa caaaaaagaa ctagcagatt atgaaaagtt gaagcgttgg
    15421 ctaccagttg acatctacat tggtggagca gaacatgcgg tacttcattt actatatgca
    15481 cgattctggc ataaattctt atacgatatc ggtgttgttc ctacaaaaga accattccaa
    15541 aaactataca atcaaggaat gatcttaggc gaaaacaacg aaaaaatgtc aaaatctcgt
    15601 ggtaatgtag tcaatcctga tgatgtggtc gaaacttacg gtgcagatac actgcgcatg
    15661 tacgaaatgt tcatggggcc attagatgct tcgattgctt ggagcgaaaa tggcttagaa
    15721 ggaagccgta aattcttgga tcgtgtatgg cgtttgatcg ttgatgagaa caataaaatg
    15781 cgtgaccgta tcactacatt gaatgatggc aagcttgata aagtgtatca tcaaacagtg
    15841 aaaaaagtga cagaagacta tgaaaatctt catttcaata cagcaatctc ccaattgatg
    15901 gtctttatca atgaagccta taaagtggac gctctgcctt atgaatatat cgaaggattt
    15961 gttcaactac tcgcaccgat tgctcctcac atgggtgaag aactatgggc aatccttgga
    16021 aatgatggtg gtatttctta cgcaccatgg ccaacatacg atgaagcagc acttgttgaa
    16081 gacgaagtag aagttgtttt ccaagtaaac ggtaaagttc gtgcgaaaag caatgttccc
    16141 cgagacttag gaaaagatga gctagaaaaa gcagcattag ccaatgaaat agtgcaagaa
    16201 tatattgaag gcaaaacagt cagaaaagtt attgcggtac caaacaagtt agtcaatatc
    16261 gttgctaatt aattggctct ttgtcaataa ggactgatga gttgtgcaaa atcaaatctg
    16321 ggccagaatg aacttcattc tgtctcagat tttttgttat ttcaaattga ttaattgatt
    16381 gatcaaaaag gttttgattt tcatgttctc aaacacgttc aatgtctttt tcttctgaat
    16441 ggtcttgtaa gagatctctg taatcatcaa atttttgtct attaatctta gtattttttg
    16501 atgtataaac tacctgaaat tgagagtaca taccaaattc ataaattttt tattagtggg
    16561 actagtgatt gtatggattt tgacgcataa tgaatgaagt atgagaaaag gagagacaaa
    16621 tggatcaaga actatttatt atcgaagtat tatcagctaa acaaaaaatt atcgagaaag
    16681 cgaaaaaaag agcgaaaaga ataatgttca agcttttaag cttagtattt ttctctggtt
    16741 tgcttttttt cggagctgta tcgttcctat atcgccatat gagtgcagta gtccgttcag
    16801 ctgaagggat gcaaaaatta aataatttgt atcacttttc gtggggagtt ggcggaataa
    16861 caattgttgt gcttattgtt tttcttctac ttatttggct ccgttaccat caattgtcgc
    16921 gtcatttcga tcaatggctt agtcaaagag cacaacagtt tttacataat aaaccaactt
    16981 ctcaagatga tgactatctt tattttgaga agacttcgac gagtcaagct tttcggatac
    17041 aaaaaagtga ttgccagtta ttgctgagat cacttgatga tttacctatc tacttaggcg
    17101 aaagcaaatc aaaattcgga atgaacacat tccatatttt tttactagaa aacgaaccca
    17161 gatgggaaaa aagccagtct tcgcctggtg gatacctgac aactaagatg agtacattag
    17221 tcactggttt tttcctcatt cttttagctg gaacaatcta ttatgggaga tacactcagc
    17281 caaaaatgtc ttctcatata aatgctgctt ctcacatgac aatgaactca actaacgata
    17341 cgcatataca aaagacaaat gaagggttgt tagctgatcc taagcaaaag gtaaatttga
    17401 caacacaaaa gataaatgat ctcaaacttg atacagagac gcactctctc tatatgacaa
    17461 cagatagtgg tgctaattgg gtatttgtgc cgattgattc gcaatggttg cgttttggcg
    17521 aatacaccct gacaacgggg ctgattcctg aaggttattg gatggacaac acatatgata
    17581 tttccgccga tttctcatgg tttatctatt cttctgggga tgatgtacgt ctgctgactt
    17641 caagagataa tggtaaaaca tggcaaacgt ctattatcac ccaatcagtt cagccgatac
    17701 gttatcgaaa agcggtattt tatggcaacg atggtctatt tatctgtaca tcagccagtg
    17761 ggatgtctgc agaaactttg tacatttaca ctactatgga tggcggaatc acttggataa
    17821 aaagtggaag tacaatgatc aatcagccag tacaaaatgt cagcttcgtt acaacttctt
    17881 taggttttgt ttcgacacgt gaaagtttgt tttatacaaa caacggagga cgctcattca
    17941 aagaatcagt tctgtcgatt ccggaaaact atcagacagg ggggatagat ctttttcaat
    18001 caccaaatga agttactcaa ataagcgcga atacgttaga gacaaaattt tatttgttga
    18061 aaaaaggacc aatcgatgca gggaaaatgt ttgcctgcct cttccgttca actgataacg
    18121 gggaaacatg gcaattcgtt cagcaactat cgcaagtaga acaaggagat taaagaagag
    18181 agattgtgag cctgacgttc agcaccgagt cacaagaaac aaattcaaaa aacagcttct
    18241 catatttgtt gaatagtgta actcgtgatt cggagttgac aagagcaaca agaagcgatt
    18301 ttgaagtata gcttctcgta ttttacaaga tcgtgtctta ttgccgatag gttgtctctt
    18361 gaacaccgtt tattcgtaaa aagggattgt gacaagtctt ttgtcactac ttaccgaacg
    18421 aaactgaagg agctatccaa aaagtatcat tagtattatt ctttgtgttt ctagtggcac
    18481 cactagtaca tttaaaaaag ctatcgatca tggactaatc atacatgatc gatagctttt
    18541 tagataatgt ttgttacgct atctgaaatt gactattata aagactggca taaagcgttg
    18601 gtgattggag tagttcagaa tgtgttcctt tttcgacgat atcgccattc ttcattacaa
    18661 ggatcatgtc tgcattttca atcgttgaca aacggtgtgc aatcacaaaa cttgtcctat
    18721 cttttgtcac agcttccatt gcttgctgaa tcaatgcttc tgttcgtgta tctacgctag
    18781 aagttgcttc atctaaaata acgacaggag gattcgctag aatgactcga gcaattgtca
    18841 ataattgttg ctgtccttga gataacgtgc cgttttcgct agaaatgatc gtatcatatc
    18901 cgtctggcag tgttcgaata aagtgatcac attgtgcgat ttcagccgct tcgataattt
    18961 gttctcttgt ggcatccatt ttcccgtagg cgatattatc agctaccgtt ccttcaaaca
    19021 gccaggtatt ttgtaaaacc atcccaaaag aacgacgtag ttctccacgt gaaagcttgg
    19081 taatatcaag accgtcgaat tcgatctttc ctttattcag ttcataaaaa cgcatcagca
    19141 gattgactaa agtcgttttt cctgcaccag ttggaccaac gatcgctacc gtttgttttg
    19201 gctttactga aaaatcgact tgattcatca atattttatc tgatgtgtaa ccaaactgta
    19261 catttttgaa agctattttt cctttcggtt gttctaaaag tcttgcatct ggaaggtctg
    19321 gaatttcatc tgtttcatct aatatctcaa atatcctatc gattgctgcc attgcggatt
    19381 ggatcgagtt gatcacataa gaagcggtag aaattggttc agaaatctga ttgatgtact
    19441 gaagataagc ttgtaagaag ccgatcgtca caccacctga tagaacaagc atagcaccga
    19501 ataccgcact tatgatgaag gcgagttgat taatgaaacg aatggccgga tagatagcaa
    19561 agttcataaa ttgagcacgt ttaaaagcgt tgtattgctt tttatttact tcgtgtatag
    19621 cagcttctgc atgagcttgc tgattgaatg ttttgaccac tagattacca gctaagattt
    19681 cttccattcg attatttaaa acacccagtt catactgatt ctgttcagaa atctgtttgt
    19741 ttttgttcgc aatcttagtt gtaacaattg aactgccaac gatcagcaat aagacgagca
    19801 aagtaagctt gctttcgata taaaacagca tcagaccagc agcagctatt gttacgacag
    19861 aagtaaaaaa ttgattgata cctgtcaata acacttgaga aagttgattg agaccggtag
    19921 ttgtccgact aatgatgtca cctacttgat gattgtcaaa aaacgacatc ggtaatgttt
    19981 tgaatttttt tgtgatttct tttcgcaccc tcaatgtgat cttttcgctt aacgctgcca
    20041 ttgtccgttc ctgaataaat gaagtgatgc tgcttaagac tgaacagccg atcagcaata
    20101 agacagggaa caacaatgct tgtttgatat cactgaaaga aagctgtcca atacctgttt
    20161 ttcttatttc tgataagaga tcatcgatcc cgattcccat gatcaagggc atggctacga
    20221 ctaataggtt cccgaataaa ctgcatagaa acaatccgta aaaatattta tgttcaggtt
    20281 tgatcatttt ccaaaaacgt atcaaagcac gcgtgttcaa cgtttttttc ttttccatcg
    20341 tatcccttct ttctatattc cttgtgattt tgcaaactcc tgataagttt ggcaattaga
    20401 cagtagttct tcatgagtac cttgtccaac gatttttcct tcatctaaaa caatgatgtt
    20461 atctgcttgt tggattgtac tgaggcgttg agcaacaatc acgagagttt tctccgacat
    20521 gtgtttatga agggctgctc ttaatgctgc atctgtttta tagtctaaag cggagaaact
    20581 atcatcgaat acatagatct ctgctggttt gatcaacgct cgagcaatac atatccgctg
    20641 tttctggccc cctgaataat tagaaccgcc ttgagcaaca aagctgtcca atccgtcagg
    20701 aagggtgtcc actagttctt ctaattgagc gatcttgatc gctttagaca actcttctgt
    20761 tgaggcatat tcatttccca tctgcaagtt gcttaaaatt gtcccgctga ataagaaagc
    20821 cttctgaggg acataactga tgtgggagcg gatctgttct tgagtcattt gagtaagagg
    20881 aataccacca agggttactt ttcctatcgt agggtcacta agtctcaaga gaagtttcgc
    20941 caaactactt tttccagatc cggtcccgcc aacgatcgct gttgtttttc ctttaggtat
    21001 tgtgaaatca atatcttcta gaactggatc agagatttca gtatatttaa atgtgacatg
    21061 ttcaaaagca gctgcatttg tctgatcaaa ggttggttca gctactgttt tgatcgtctc
    21121 ttcctcaatt tcgatctctg cttgcagtat ttcttctatc cgtcgtaatg aggcaaacga
    21181 tttagggata atgaccaata ccatagctgc gatcatcaag taagcaagtg tcagcataga
    21241 gtattcgact acagcagtca cgacaccgat ttgtaatgct ccttctgcta caagatttcc
    21301 gccaaaccac aaaatagaag cataaacgat tcccatgagc aaaaaagcaa ttggagtgac
    21361 ccaagcaaat attcggttca ctttgatcat ttgattagca tagtcagcaa agctcttatt
    21421 cgttcgcttt tcttcatatg attgattatc aaaggcacgg atcatattaa tcccagtaaa
    21481 gaattctctc aatgtgatgg tgatccgatc catttttggc tggatactca aagataaagg
    21541 tgcccctcgt ttcatcagtc gataaacaat ccatacataa aaaacaacag agatcaatgt
    21601 aacccatgtt agtaatagag aataacgaaa catcatgaga atggtgaaaa cgcaaataac
    21661 cggtgctggt aagatcattt ggcaaaataa aacaatcatt tgctggacat tatcgacatc
    21721 attcgtcatt cttgtcaaaa gagatccaga actaaaacga ctgatatcct tcattgacag
    21781 ctgttggaat ttacggaaat atttctcccg cgtttggaat ccaaacctag cggaagccaa
    21841 tgctgaaaag taactagagg caactgcagc gattgttcct agaaacgcta caagcagcat
    21901 ttcaactcca atttttttta taactgaggc ttcgccactt gctatacctg tgtcgatcag
    21961 ctttgctact aattttggta cacctaatgt accggcgatt tgtaaacaga tcatcacaaa
    22021 ggtaaggaga gcgagtcctt tgtttttctg taagaatgtt tttaagatag acatattatt
    22081 cctccttttt tcctgatact tttcgattct ataccttcaa gtaacttgaa ggtcaataga
    22141 aaaaagaata aactgaaaaa gaggtgagaa aaaatgaaaa aaatgtatac gattggccaa
    22201 gtatcggaac tatttgattt gccaaaatca acgatccgct attgggatga acaaggatta
    22261 atccgttcaa gtagacaaga agagaatgat tatcgattgt ttgatatcga tgatattttt
    22321 atgctttatg atatcgtttt ttatagaaaa ttagatatac cgatcaaaca gatgaagaat
    22381 ttatatggaa aaacattgac ggagttatat gagacacttg atgaaacaga aagaagaatc
    22441 cataaagaac tggtggtgat gaaacaaaaa caaaaagaga taagggagcg aaaaaaacag
    22501 ttgaaattga tgatcgatac aaacgaggaa gaatttcctg tagaagagat cccttttgac
    22561 tgtatgatct caacggagtt tgaagatatt gtggaaatca aaaaatttct acctaactat
    22621 tcaagctttg ggatgatgag tatgccagct tccagttcac agacgatgta tggatttttt
    22681 atcgacccta gtgaagtaca tttatttact caagacgtga tttgggagaa aaaagatacg
    22741 gctgtttatc gtcgattctt attgaaatcc gagatgaacc atgcggaacg taataatatt
    22801 ttagaaatca gagaaagaat gtatgaaaaa ggatggaaaa caggagaagt gatcggccag
    22861 tatctattga cgaatacgga tgaaaacaat atcagaactg aatattatca tgcatggata
    22921 gaaatgaaaa aataggaaat atgtgtttaa gataactcga aaatgatggt tgttttagtt
    22981 ataaagaaaa attttctggt tcgattacgg gtttaatgtg ggggattatt agtcgtggat
    23041 agatagaatt ttagtttttt agaggaaata tgtctttaaa aatggaatgg ttgcaattct
    23101 tagcgatata tacgatgtaa ttgtcctctt aaaaaagtat ggaaaaataa ttgtattggg
    23161 tgttatgtat aattcatggt gaactgagac taatgagaag aaaaattcat attgttatga
    23221 gtgagattgt atcagatgag aatgataaat taaataggtg cataaaagca ttacacttaa
    23281 aatacattgt tgcttacatt attacaatat gttaataagg caaaaataaa tagatggatt
    23341 gaataaacat attttttaat caaatagtcc ctactgtgac tttcctcagc tatcggtgat
    23401 actaccgata gcattttttt gcttataaaa taattataag tatttagaga tttttcttct
    23461 aacattcttc aaacaagaaa aatcacaaag gttattgtta tttttatata ttctttttaa
    23521 gaatgattat ttttttatag aaattttaaa aaataaaaca cgttattgat ggatagttag
    23581 tttgttattt ggtaatatta tagaagttga ctggtagtga tttatttttc gttgttttat
    23641 aaaaatgtta ttttttggaa aaattcacaa atatgtaacg aatgtttttc tggaatttgc
    23701 tgtgttaaaa agcagtatga ctaatataaa tactattgtc atttatgcaa ttttttatgg
    23761 atagtaattt tagaggggaa tcaatgaagg aagaatagaa gggaaaaata gttgcaaata
    23821 cgccagttag caaaaatagc aatacatctt caagctttaa aattcgagag aatcatcttg
    23881 gtagtggaat caactacaac aaaaggatta aaccaattaa tagatagaat taccaatgga
    23941 aaaatagaaa aggtagttat tctatacaaa agttgtttaa ttcgcttcgg ttatgaactt
    24001 agtgaaaccc tttgcaatat atggtacaga atatagaaat tattgacatt acagaaaatg
    24061 atgaagattt aatacagatt gtcactattt gtagatacct tttacaagga aaccgagcca
    24121 ataaagctaa gaagatgatt aaggagttga tggaagacga tacaagttaa gaaagtaaaa
    24181 ctacgcccaa ataaagagca aaaagagtaa ttggacgtgg aaaatgcaag aaatgaacca
    24241 tcgattcggt ggacagttta ttagtaatga cggtttgaga acatccatga cgagaatgaa
    24301 ggaacatcct aaatgcgttt agttgaacca agtgccaaat aatatggcca aataagcgat
    24361 cagttatcga tgaatcccaa gtattctaaa ctatatattc attttgatgc taagcattga
    24421 tatatttttt tgggattgat gaaggttaac caatacaggg actcactgat gaaattctag
    24481 agtctgacct tggtatcaac gatttagtga ttgtttctaa tggaaaagta taaaagtata
    24541 taagtacatt aacaaaataa ctattagggt tacgctccag cttgtgcaag gcactggcag
    24601 gaggaatcgt gaaatcataa ttatggttaa gccacacgga caactaaaag tcatacaaag
    24661 ctatcgaatc aatcaacaga agacaatcgg caatcattag ctttgtttac agcttacatt
    24721 gcaacgcttg agttgaaccg aaaatacgag ggaggtaacg cagccatttt gagttgggga
    24781 atctttttag aaaattatcg ggtaccttgt tgtttagtca aaattataag ggggagtaat
    24841 agtgaggaac aaatttcata aactgttaag tatgtttcta gttatgctta ttgtgatcaa
    24901 tcaatttggg aacataacgg ttctagctga gtctttagca gaacagccag agcgttcgct
    24961 gacgatcgaa gttgatcaag aggaggctgc tttgggtgag cagttccagt tgcgagtcag
    25021 aggaacacca gacctgctaa atgcattggt cattgataag agtgaggatt tgattgaagg
    25081 ggaagtgaag caactcaatg attacgaacg tctgattact tattcttccc agcattcagg
    25141 taaatacgaa ttgaccgcaa gaagcggtga tattcaatca aatacggtct caatagaaat
    25201 cagtgtacca gaagaaagca caagtgagtc ttttaatgta ccagaagaaa gcacaagtga
    25261 atcttttaat ataccagaag aaagcttaag tgaatctttt aatgaagcca gatcatctga
    25321 gccatctata acgcaggaat ctcagattga aagacaagag gagctcttga attatgacat
    25381 cggcatctct gctgagcgcc ccactttgcc gagcaggcat acacaaacgt taaagggata
    25441 cattcaagga ggcgctggcg atattcttga agaatatggg gagatggtcg tacgagttcc
    25501 tagagcatcg attggcttaa ttgagttcat tagagtggag gtcgctgatg attcaccttt
    25561 aaagccactg gcattttacc aagaaggcac agacgttgtt tttccattta cctttgatta
    25621 tgaaggatta aatgaagccg ctcagtcgta tacattcagt atcacgtttg aagttgcttt
    25681 ctttcaatca ggcggtactg agccaaataa tgactttcaa gtgagtctta cttatgctga
    25741 gcgagcagca aacacggaat tttcaattac gcctattcct tcatcaagac ccattttttc
    25801 gaaattatac tatggctcta gagaaatcga cagccaagga aatcttggga atctgctgat
    25861 tgacgggcaa gacgtgacca acagtaataa atttattttg caggtaaatt atgaaggatc
    25921 acgaaaagac ggtgtagtgg ttaccgatgt actaccgcaa ggaacaactt tggcaccgaa
    25981 tccgactaca tggagttcca ctggaaatag agaacctatt tcaggtgggg ttcggatcgc
    26041 agaagtaacg aatccaggtg aagcaaacgt tagaactcat tatgtttccg aggaatttgt
    26101 ggacaaagta tcttttaata aggaaacgaa tacacttgtt gtggactttg gtaatctagc
    26161 agagggtcaa tcgtatttta ttgaatatgc tcttgaagtg accgatgtcg acttgttcaa
    26221 tgaaggaaga caagaggatg ggttttctcg gaatcgagcg agtatgacct acaataatca
    26281 ggtaatgagc cgagactacc gcttgagaat ccctgaaagt aatcttccgg caatctcttt
    26341 aagaaaaagt gtggacaaaa atgttatcaa tctcaatgaa aatgaactaa cgtatactct
    26401 gcatgtctcg atgttttctg gaacaagcaa tacgcttgtt attgaagatg ttttggaaga
    26461 aggcatggaa tttgtgtcat ttctatcaga tattccctct ttcattgatg ccgaagtcaa
    26521 taatggaata gttcgtttca gtgcgaataa tacgattggt ggtccgacaa gttttaccct
    26581 ctcttttaag gtcaatgtag aggcgtatgc ggtcggcgat caaattttaa actttgcaac
    26641 gcttgtgaat agtgacaatc gattgaatac gagtactgta agaacaagga aaatcgatgg
    26701 gcgtattaaa gtaattaaaa ctgatgagaa tggccaaagg ctggcaggag caaaatttga
    26761 aattttatca agcgattcac aagtgataca agaaggtata acggcagaaa acggagaatt
    26821 tttaagtgaa ccgcttcctg taggtagcta tcaagtccga gaaacagaag caccggaagg
    26881 gtatctttta gatgcgacgg tacatgatgt ttttataaat gaatactcca tagaagaagt
    26941 gacgttaacc attgaaaaca tccttgatac gggtggtgtt gaactaatta aacatgctga
    27001 aggcagtggt gaagtccttc aaggagctgt ttttgagtta cagaaccgag aaggagaaac
    27061 gctacaaacc ggtttaacta caggagaaga tggaaaactg gcaattgacg gtttagcacc
//
LOCUS       DACGLI010000042        26444 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.043, whole genome shotgun sequence.
ACCESSION   DACGLI010000042 DACGLI010000000
VERSION     DACGLI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.043"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            55..843
                     /locus_tag="IXT22_001919"
     CDS             55..843
                     /locus_tag="IXT22_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4863262.1"
                     /translation="MVLLESMPDGYIYSNILLKLYLRSLKHEGKLMFNDRIPFNSTML
                     ATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDIQSFIGKSSTEADRKRKYRKEI
                     EEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEKDIENVTPSKKSKAKPVRHKYG
                     EYKNVLLSDEQMEKLKIEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSE
                     SKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            855..1124
                     /locus_tag="IXT22_001920"
     CDS             855..1124
                     /locus_tag="IXT22_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863263.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            1286..1588
                     /locus_tag="IXT22_001921"
     CDS             1286..1588
                     /locus_tag="IXT22_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863264.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            1585..1746
                     /locus_tag="IXT22_001922"
     CDS             1585..1746
                     /locus_tag="IXT22_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4863265.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            1743..2048
                     /locus_tag="IXT22_001923"
     CDS             1743..2048
                     /locus_tag="IXT22_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863266.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            2048..2404
                     /locus_tag="IXT22_001924"
     CDS             2048..2404
                     /locus_tag="IXT22_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAQ4863267.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            2364..2609
                     /locus_tag="IXT22_001925"
     CDS             2364..2609
                     /locus_tag="IXT22_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863268.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            2606..3025
                     /locus_tag="IXT22_001926"
     CDS             2606..3025
                     /locus_tag="IXT22_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HAQ4863269.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            3022..3579
                     /locus_tag="IXT22_001927"
                     /pseudo
     CDS             3022..3579
                     /locus_tag="IXT22_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
     gene            3576..3872
                     /locus_tag="IXT22_001928"
     CDS             3576..3872
                     /locus_tag="IXT22_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863270.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            3949..4362
                     /locus_tag="IXT22_001929"
     CDS             3949..4362
                     /locus_tag="IXT22_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4863271.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            complement(4820..5095)
                     /locus_tag="IXT22_001930"
     CDS             complement(4820..5095)
                     /locus_tag="IXT22_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863272.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            5549..5755
                     /locus_tag="IXT22_001931"
     CDS             5549..5755
                     /locus_tag="IXT22_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863273.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            5951..6118
                     /locus_tag="IXT22_001932"
     CDS             5951..6118
                     /locus_tag="IXT22_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4863274.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            6144..6488
                     /locus_tag="IXT22_001933"
     CDS             6144..6488
                     /locus_tag="IXT22_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4863275.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            6493..6774
                     /locus_tag="IXT22_001934"
     CDS             6493..6774
                     /locus_tag="IXT22_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863276.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            6877..7191
                     /locus_tag="IXT22_001935"
     CDS             6877..7191
                     /locus_tag="IXT22_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAQ4863277.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            7169..8863
                     /locus_tag="IXT22_001936"
     CDS             7169..8863
                     /locus_tag="IXT22_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4863278.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            8883..10061
                     /locus_tag="IXT22_001937"
     CDS             8883..10061
                     /locus_tag="IXT22_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4863279.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            10024..10710
                     /locus_tag="IXT22_001938"
     CDS             10024..10710
                     /locus_tag="IXT22_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4863280.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDAK"
     gene            10710..11870
                     /locus_tag="IXT22_001939"
     CDS             10710..11870
                     /locus_tag="IXT22_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4863281.1"
                     /translation="MTIKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            11880..12755
                     /locus_tag="IXT22_001940"
     CDS             11880..12755
                     /locus_tag="IXT22_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863282.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            12752..13063
                     /locus_tag="IXT22_001941"
     CDS             12752..13063
                     /locus_tag="IXT22_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863283.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            13053..13406
                     /locus_tag="IXT22_001942"
     CDS             13053..13406
                     /locus_tag="IXT22_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4863284.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            13396..13797
                     /locus_tag="IXT22_001943"
     CDS             13396..13797
                     /locus_tag="IXT22_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863285.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            13790..14194
                     /locus_tag="IXT22_001944"
     CDS             13790..14194
                     /locus_tag="IXT22_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863286.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            14206..14814
                     /locus_tag="IXT22_001945"
     CDS             14206..14814
                     /locus_tag="IXT22_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4863287.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGAAEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     SEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELEAKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVATTATQSQ"
     gene            14834..15196
                     /locus_tag="IXT22_001946"
     CDS             14834..15196
                     /locus_tag="IXT22_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863288.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMSM
                     GKGSMDITVIQGAKAVYVAYRQANMVDYISFDEFIDKWDFDMEVAVAVYSTMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            15199..15381
                     /locus_tag="IXT22_001947"
     CDS             15199..15381
                     /locus_tag="IXT22_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863289.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            15399..18719
                     /locus_tag="IXT22_001948"
     CDS             15399..18719
                     /locus_tag="IXT22_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4863290.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQSKGEFKTYESTMKDLDNEQQHLKSSASLVESEYKKWQ
                     ATAGQSATESEKLAKAQEYVGKQSDIAEQKIEVLKKQLDATQKEFGETSTEALEMKTK
                     LNDAEREFEELSNAAKNVDTSTVDDIGKKLDMGNLMEATDHLSVIGDKLIDVGSKSIE
                     AAGKAQAMQAQFKQVFGSLEGEAQDAVEGMAEEFGMLPNTIKPVFTQYTSMFKGLGYD
                     TKEAMELAGDSTQLAADAAAFYDKSMDDASESLNSFIKGNYEGGEQIGLFANDTQMAA
                     YAVKHNLIPATEGAKKASEESLLAVEKAQSKYADAIKKHGEGSLEAREAALKLKDAQD
                     KINEELGPQTQKWSDLDEATKQAVRVQYAEDMQKLAGATGQASRESDGLENQMTRAKQ
                     ALEDFYASLGEDILPVFIKGLQAGAKALQGLAEWWSKLDGPMKNFILALGGILALLST
                     LAPVITAVVTIVGTFGSTVLLPIIGIIAGVAAVIAIVITAFQNWGAITDWFSDLWKKF
                     TDWLGDTWESIKESASSVWDGVKETWSGFVDWVQEIWQGVSDWFGELWSGLVEGASNI
                     WQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI
                     FDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNG
                     IWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWN
                     SISSTASNIWSSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGIT
                     STISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKI
                     SSVFDNLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAG
                     PEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQ
                     QIIDSITKVQNDNASAWR"
     gene            18770..19507
                     /locus_tag="IXT22_001949"
     CDS             18770..19507
                     /locus_tag="IXT22_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4863291.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFTLNDYVFSFEGLVVGTDIVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            19517..21808
                     /locus_tag="IXT22_001950"
     CDS             19517..21808
                     /locus_tag="IXT22_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863292.1"
                     /translation="MIDNLLTIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDSIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            21832..23934
                     /locus_tag="IXT22_001951"
     CDS             21832..23934
                     /locus_tag="IXT22_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863293.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSINFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGA
                     DYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTTPTFSPQAYHP
                     WIQFRAQDGILGEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADHTVKF
                     PIESGDHQIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLT
                     DVWSLTFTPTNVVASSPKLFRVYQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGT
                     GMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINE
                     VDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVS
                     IYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKW
                     RRNSSYGSDYTFAITYTI"
     gene            24097..24543
                     /locus_tag="IXT22_001952"
     CDS             24097..24543
                     /locus_tag="IXT22_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863294.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            24545..24682
                     /locus_tag="IXT22_001953"
     CDS             24545..24682
                     /locus_tag="IXT22_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4863295.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            24720..25013
                     /locus_tag="IXT22_001954"
     CDS             24720..25013
                     /locus_tag="IXT22_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863296.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            25010..25234
                     /locus_tag="IXT22_001955"
     CDS             25010..25234
                     /locus_tag="IXT22_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4863297.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            25231..26256
                     /locus_tag="IXT22_001956"
     CDS             25231..26256
                     /locus_tag="IXT22_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4863298.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNPYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
BASE COUNT         9410 a         4010 c         5629 g         7395 t
ORIGIN      
        1 aacaaacgat actactattt aaaactaaaa gagaactttt tcgatagcga cgagatggtt
       61 cttttagaaa gtatgccaga tggatacatt tattctaata ttcttctcaa actttattta
      121 agaagtctga aacatgaagg caaactaatg tttaatgaca ggattccatt caattctaca
      181 atgcttgcga ctattacaag acactctgtg ggagttgtag aaaaagcagt acaaatattt
      241 cgtgatttac aacttattga ggtattagat aacggagcaa tttatatgtc tgatatacaa
      301 agttttattg ggaaatcttc aactgaagct gataggaaga gaaaatacag aaaagaaatt
      361 gaggaagcaa aacagaattt aataacaagt ggacaaatgt cggacaaatg tccggacaaa
      421 actacaccag agttagagat agagttagag aaagatatag agttagagaa agatatagag
      481 aatgtaacgc cttcgaaaaa atcgaaggct aagcccgtcc gtcataaata cggagagtat
      541 aaaaatgttc ttttgtcaga tgagcagatg gagaaactca aaatagaatt ccctaatgac
      601 taccaagagc gaatagaacg gctatctgag tattgtgaat catctggtaa gacttataaa
      661 aactatttgg caactattcg aagctgggca agaaaagaaa aaagtgaatc taagaacgca
      721 agcagtggat acaagcgcac aggaagacga gagaagcttc ctgagtgggc aatcgaccaa
      781 gaagcctatc tcaagaaaaa agcgctagaa cgagctaata gacaatcaaa agcaccattc
      841 taagaggtgg gaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
      901 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
      961 tcgaaggaat taagaatgat cgttcgagtt ggagtaagct cagatactat ttcgcacttt
     1021 atatcgatac aacacaatta agaaatttag catataccaa attactattt gttgattgtg
     1081 ttaaaggctt gcaaaaacat cttaatgaac ttgagcaggt gtaatcagat ggacctaaag
     1141 acatttacag cacagattga actaatgcat caagaagctt taagacaaag tgtatcgtac
     1201 gaagacaagt ggctcaacac gttccacggc ggacgtgaga gcgcacttga tcaagtactc
     1261 aaattactga aaggagaatg tcgggatgga taagaaagcg gcaatgcagc gaattatcga
     1321 attgacttat tcagaagatt ggcaaaatga caaagaagct gcttcagaag tgatgaggct
     1381 tggaagagcg atgtgggcag acaagagcaa caagccaaga ccacgaaaaa tcgcaatttg
     1441 gcacggtgac aaacttctag tgatagggac agctgaacag ttagcaagtc tcacaggctt
     1501 gcacgagaaa atcgtgagga aaagagcaag gtgtggctac acagacgcta agaagagaac
     1561 gtttagatac gtggaggaat catcatgaca acagaagaag tgattcaaat gcgtattcga
     1621 agccttcagc gtgagattga cgatctggaa cgaacaaagg cagtgatggt caatgaaacg
     1681 gcgagaaagg caatcgattt gcacatagag aatttaagaa gggaaatcca tcgattggag
     1741 gaatgagcgt ggataagaaa gcagcaatga aaagaattgc tgaattaacc aagtcagaat
     1801 cttggcaaga agacaaagaa atagttgcag aagtccaaaa gctcggtaaa tcaatgtgga
     1861 ctgaaaagcc caaacggaga acgccgagaa aaattgcaat ctggcatgat gaccgaattt
     1921 tagtaacagg tactgctgaa cagttatctg aaattactgg attaagcaaa aacattatct
     1981 gggatagagc taggagctta tggattgatt caaaaggacg acagtttagg tatgtggagg
     2041 agagataatg gatctcatta cacaatacag tgacatcatc ctcaagaaaa tcatgatgaa
     2101 gattcagaaa gataaaaaat caaaagaacg agctgaatta gttaagttag aaatggctga
     2161 aacaggagca ggagtgcgaa gtagcaggca ttggaaagca gcagcaaaca ttgaatttta
     2221 ttacaacgaa attcaaaaag ggttcgatca gatgcgtgag ctggatcggc aaacaaattg
     2281 gagcaagaaa cttcatcaag atcgtttcaa atttgtagag aagtataaag aaatattaga
     2341 agagtatttg aggaggacag caaatgataa aaaaactcgt tcaattcagc atggatttat
     2401 atgatatcga atcaggagca acactatctg tggaatcgga ccatctaatc ataaattttg
     2461 gtggaaagcg ccagattatt ttgtgggtag ttgatgatgt actgtttcca gaaattgttc
     2521 atgatttcga agaatcaaaa gcggttgagt ttgaaatagt gaaaaaagta atggaattga
     2581 ttgaaaaata cgaggaggac agcgaatgat accgaagttt agagcgtggg ataaacgaaa
     2641 gaacgtaatg agagatgtag ccgtcttgca ttttactaaa aacggcaaaa caaactttat
     2701 tgaatattgg ataaatccta ccgaattgaa atcatatcac gtgcgaaaca tcgacctcat
     2761 gcaatccaca ggaatgaaag ataagaatgg tgtggatata tttgaagggg atatagtatt
     2821 agtcagcgtg cgaaatggct tcgattactt agataataaa gtctgtattg tcaaaaattc
     2881 aatagattat tccggattag tttgtgccac tgttgatgaa gacttagagt atcaaatttt
     2941 taacacagag ctgtttgaag aatacacgta cgaagtcacc ggaaatatat acgagaatag
     3001 cgagttattg gaggaacagc gatgaataaa caggaagcaa tcaaaaagtt agaaagtatt
     3061 aaagcgatag gaaatgatgc aatagctgct tgctataacg agagtataaa ttcaggtatt
     3121 acgttaatga aaaaaataga cgaaccgcag aaaccagtta ttccacaact cgtggccggt
     3181 tggcttgaga aatctacgga cccttttaca aaagctgaaa aaatagcgta tttaatcaaa
     3241 tctaaagatg gtgattcata ttatttctgt gattggtttg tacgagatgg catagtgacg
     3301 caagagcaag gagaagaatt actcgcttgg gcaacaagac aatcatatga aacactattg
     3361 agcctataca acggctaaga ggttgagaaa gagccgttat gggcaataaa gaatgccgat
     3421 ggaaactatc ttactaaatg tgctttatgg ggaaaagatg gagtaaatta tagttttgaa
     3481 tgcaatccat ctcatcgatt gcttttcact gataaagcaa cagcggatgc tgcagcattg
     3541 ttggtgaatg gaacagtgga agaggtggta gaaagatgaa actaaaagac ggattttacg
     3601 ctagcagtca cggtatcggc ggtttaatgc tagatatgcc gacaaagaac cctaaaacac
     3661 gcaagaaatc aaaattcaaa gtcggtgaca tggtccgctg tgaagcagaa gagttcgttt
     3721 atccgttcag aggatacgtt aaaaagatac tgtcaaactc agcaatcatt cgtattgaaa
     3781 atacaatgaa gtgtgatcgt tcgactgcaa aacacaagca ttatttagct gtagcgagat
     3841 tagttgacat ggaagtaatc aagagcaaat aaaaaaagcc ggatcgctcc gactgattca
     3901 ataaatccaa cacatttatt atatcacata aaggagcggt ttgacttgat gcaattgtta
     3961 cgagaggtag atttcaaaca gacaagatgt aatgcgagag atgtgctgaa gaactttcgg
     4021 cgtttggagc ggatggcagg tcgctctttg atagatatta agtcgccgat tataacggat
     4081 atgccgaagg caccgaagca tggcaataag gcagaagacg cgattattca gatgatggat
     4141 atagaaacgg agagagatgc gattctagcg gctttgatgg ctcttagtct gattagtcgt
     4201 cagatactct actacagctt ctgtgtgcca gatagcttct caaactacag aattagccgt
     4261 gaagtgggtt attcagaaag aagtatacaa cggatgaagt cggaagctct aatagagttt
     4321 gcagaagcat ataaacacgg aaaaataatt gcttataaat aatttggcgg ttttttggcg
     4381 gaatgatggc ggtttttaga catttaccag tgttattatg gtagtgtcga aagattagga
     4441 aacaggatcg acaaaataaa cgaagggagg caatctccct catcgtttta aacttcttct
     4501 tagatagaca gcaactaatt atgaagaaaa ggatgtgaat tcaactcctc ctaaattctt
     4561 catcggttgc tgtttatttt gattagacag cagcactcac aaaactaaac atgttcttgt
     4621 cgtctttcaa ctgctgctgt ctattaattt atgtattgga gggaagaaaa atgaaattat
     4681 cagtagaagg cactccagaa gaaatacaag aattgctcca agctattggt agtagcaagg
     4741 agcaaaaggt aagtgtttct aattcagata ttgacggtat ttgcaattgt ttaaacagag
     4801 aaaaaatatc taatccttac taagagaaaa tatgttcgtt aatgaatttc caattttcct
     4861 ctgtagctct accttgataa tttttttgca gttcacagat gaataaggaa tcgttattat
     4921 caagtactgt atttaatttt tcacacattt gatttggatt caaattagtt ttaactaacc
     4981 aaaaagattt ttgtagcttt atatatgccc caaattcttt tattatttca aatactttat
     5041 catacttttg ccctgggtta ttaagatcat aactaatcat gtagggttta tacatgttgt
     5101 cttgcacatc cttgttttat atttcagcgg accactcgct gataaataaa attatacgct
     5161 tagtatttat tttcacaata ttaatttatc gtaataactt ttgagtaaat agaacaaaaa
     5221 acctgcacta gtttccgcta gtacaggcag tgactatatc ggttgataat ctagcatata
     5281 ttaaaaataa ttgcaagaaa agaaatttat agtggtttat accaaattat caaagcaatg
     5341 ttattttgtt gctgtctatt gttttttaat tattcacacg ataactaaag gtgggtgaag
     5401 agaaatgatt ccattaataa tttcaatttt tgcgctctgt cttaatgtct atatgattgg
     5461 atttaaaaat gggcaaaata aaaaatagta gcagccaaga ataattttat agtgtcactg
     5521 tggcggaaag ggtagacgct aagcatgtgt gctaggtcaa tgcttcggca accatgcaag
     5581 gttcgattcc ttgccagcga cattaaatgc ctatgacggt tacgactacc gaaaaaagat
     5641 cgttaagaag ctatacggtg ctacgtacgg caatgtagta agtgtgctat ctgtacacca
     5701 ccaagcttcg gtcactgtgg cggaagtaga agacgcagcg gtaaatggcg agtagcctcg
     5761 tgagagcctg gtaagttctc gtgagtggtg caatcccact ccagcgactt taagcaaccg
     5821 aggcatcggc ggtttaaaaa tataggggtg cgcaatttcg tacgcgtttt gtgcatcgtg
     5881 caagttacta ttacatatta gatcactctt tgagtggtct ttttattttt gcacaaagga
     5941 ggaaacaaca atgtatagac cacaatactt agaacagaag tatgaagtaa tcactgttca
     6001 taaaggtaat ggcgaaaaag tatatgagta tagaagacca ataaagagcg atacatataa
     6061 acgaaaggaa aacaatgaag ttattccatt gtatggcaaa agaatagcta agcattaaat
     6121 aagattgcga aaggagacgg aacatgaccg aggaattcta tagatggcta ttacagttga
     6181 caagagaaga tcgtttggtt aagttctatc agtctcctaa atggcgcagg cttagagaga
     6241 aagcgatgaa acgagatcac tatgaatgcc aagagtgtag aagactaggt aagtatcata
     6301 gagtagagaa cgttcatcat ataaaggaag tcaaggatag acctgactta gctttagatt
     6361 tagataatct tatttgttta tgtgttgaac atcataatga agttcatggc agatatctta
     6421 cagcattaga taaacaagag aagaagatag aaagctttgc taacttcgat gcaagtgaaa
     6481 ggtggtaagt gcatgatcat caatgataat ggcagagagt atgatacaga aaagattgaa
     6541 gagtattcat cttatactca gggattaatt aaacgtttga tatacgttcg ctatgtaggt
     6601 attagggatc tgttatcaga taactgttgt agtaaataca aagtgaatca agtaagagaa
     6661 gcgttgaata aagataataa cgtcgaaaga ataaaaaatg tttttggata tagtattgaa
     6721 gagattaatt attacattga cttcgctgaa gctttcattc cgatggtgag ataacccccc
     6781 cttaaaataa atcgcaaatt ttttgggggt gatgaaacgg agggggctgt caggaaaaga
     6841 gattttttcg aactttatca tgaaaggagg gctaaaatgt ttaaaaacga attgtctcaa
     6901 aatcgctaca gagaaaaatt acgccgctct ttaataagcc aattggaaag tcagaaaaca
     6961 aatattgagc cattcttaga taatgttgat cgttatatca gtttatggga aacggcgata
     7021 tcactggaag aagatatatc cgagaacggc attagactgg agaatggtaa aaagaatgaa
     7081 tcagtagcgt tgcttgtttc tgtcaacaaa caaatgggat tgatgttgga taaacttgcc
     7141 attactcctg aattggtagg tgaagcaaat gaatcaattc ctgagttata agcatattga
     7201 aaattggttc aaagctatag aagaaggcac tatcaaggta tgcaaagagc aattattgct
     7261 aaaaaattat ctagaagaaa gagtctttac tagagaagat atttacttcg ataagcagat
     7321 ggtagaggat tcaatcaata taccagcaca atactttcca ttcgaattaa ttccgtggga
     7381 aaaatttcta caatgtttta tttatggtgt tcgatggaaa aaagataaaa cactagtgtt
     7441 caatagatat ctttcattaa tgggacgtgg taatggtaaa actggttttg cttcttggaa
     7501 caacttcttt ctactaaccg ctaaacacgg tattaaaaat tatgatattg atatctatgc
     7561 caataatgaa agccaagcaa agactagttt tgatgatgta tttaaagtaa ttaaagatca
     7621 tcctgattta gataaaaaag tatttaaagc tacgaaggaa gttattcaaa atatcgctac
     7681 aaacagcaaa cttcgttata acacggcaaa tgctagaaca aaagatggga agcgaccagg
     7741 tgcaaaccgc tttgatgaaa ttcacgaaaa tgaagattat tcaatgataa atgtggctac
     7801 ttctggtggt ggtaaaattc gagattatag agaattttat gatacaacta atggtcatgt
     7861 tcgtggtggt ccgcttgatg acattataga agaatcaaaa atgattcttt ctggagaact
     7921 tggaattgac aaggatggag cagaattttc tagtttgttt ccatttattt gtcgcttgga
     7981 taacgataat gaagttgatg atcccgacat gtgggaaaaa gcttgtccaa ctattaatta
     8041 caatgcagat ttaaaacgga aaatgtttca agaatactct caaatgcaac gtaatgctgg
     8101 tttaagactt acgttcatga ccaaacgaat gaacagacct atggaagata cacgatttgc
     8161 tgttgcttca tatgatgatg ttctgcatac gaaagaaaaa gaatttcctg aaaaaatgga
     8221 tgaagtgata ggaacagtcg attttgctga tagacgagat tttgccagcg ttgggttgct
     8281 aggaaaatac gataaagatg tttattttac acaacatact tttatccacg aatcagccct
     8341 tcgattacaa aacatcaaac gagaggttat agatatttct atagatcaag gaaaatcaca
     8401 gatcgttcat ggaaaaaata tagaagctga ttatattgta ggttggtttc ttgaaatgag
     8461 taataaatat tatattaaaa aaatcgctat ggatatgtac cgtgcaaaaa tattgaagcc
     8521 cgctttagaa gaagcaggtt ttactgtgga aattgttcga agcggatctg ttacacatgg
     8581 tatgttaaaa gatctggttg atgacctttt tattaatcaa cgtttatttt ttggtgacga
     8641 tgcgattatg cgttggtatt gcatgaatgt atatgaagag catatttcta atggaaatat
     8701 acgctatgaa aaaatagaac ctgaaactag aaaaacggat ggcttttttt cattccttca
     8761 tggtttgaat tttttagatg atatttatga ttctgctcct gtaacagtca caaatagctc
     8821 agtagaaaat acaggaactg gatttactcc tctagtattc taacttgaaa ggaggtgaga
     8881 aagtggggat ttttcaaaag gcggtaggat acttcacaaa aaaagcaacg gttcctttag
     8941 aagaatactt ttgtaaattg caagttgatt ttgtgtatcg aaaatttgcg attgaaactt
     9001 gtattgattt gattgcaaat gcgatgagta aagcggaatt caagtcatat gaagatggaa
     9061 aaaataaaaa gaatgatctt tactataggc tgaatgtagc tcctaataag aaaaataatg
     9121 caacagaatt tagaaaaaaa ctgatcagga gattaatatt ctacaatgaa gtattgatcg
     9181 tttctccgtc taataattct agcgaaatat ttattgcgga tagttgggat gtcacagaat
     9241 atgcattgaa agatgatgtg ttttctcaag tgcaaattaa caacatagtc cttgatagag
     9301 aatttctaga aagtgatgtt atctatataa aatacgcaga tcaacaaatt aggcaactag
     9361 tcgatgcgta ttatcaagcg tatgggaaac tcatttctag tgccatgaat gtttacaagc
     9421 gctctaacgc tcgtagatac gtactgaaag ggaatttatt ccgaccgcaa gacaatacaa
     9481 cacaagatca aatcaataaa atgatgacat cacaatttaa ggcttttatg gaagctgata
     9541 atgcaggtgc ggtatttcaa ttacaaaatg agtacacatt agaagatttc agcggaaact
     9601 tccaaagcaa ttcaagagat ataaaaaact taatagacga catctttgag atgacagcag
     9661 cagcgtttca cgttccgaaa aacctactaa agggagacat gagtgggtta tcggatcaag
     9721 tggacgcttt tttaatgttc gaaatcatac cgattgctga acttattcag gatgcgttta
     9781 acgctagtct ctatgaagta gaagaatact tgtcagggaa ttttgtacgt gtggatacaa
     9841 ctatgatcaa gattactagc ttcaaagatt tggttgacgc tattgatgta ggcattagaa
     9901 atggagtatt tacaatcaac gaaggaagag aacgcgttgg aaatgatcgc tctgataagg
     9961 cgatggcaga tgaaatattt ataactaaaa acaatcaaca agtatcgaaa ggaggtgagg
    10021 cgaatgacga caatgaaaac atttctagca gtaaagaatg aaggcgcagt accgcaaatt
    10081 tttattcagg gatttattgg ttctagttgg ttctttgaag ggaatactga caagggaatc
    10141 aaaaatattt tggatagtct aggtgatcaa gaagaaattg aagtagtaat taattcaaac
    10201 ggtggagacg tatttcaagg gattgctatt gggaacttac ttaagtcaaa taaagcaaaa
    10261 gttaacgttg tgattaacgg cttagccgct agtgctgctt caattatcgc aatggctggc
    10321 gatactataa aaatctacaa caatgcacaa ttgatgattc accgcgcttc cacatacgga
    10381 gaaggaaatg tcgatgactt ccgtacgatt gctgaccaac tggaatcaat tgataaatcg
    10441 gtaaaggctt catataaaac acgattcaat ggcacagatg aagcattgca agaacttctt
    10501 gaaaaagaat cgtttatgga tgcagaaaca gctttgagtt atggattggt cgatgaaatt
    10561 atcgatgcag aaaatagctc aggtactgaa gctaaaaaag aacaaagcgt tgaagaaatt
    10621 ttgaatgacg ttaaagaaaa aagagcagaa aaaattgctg catttacagc agcattaaat
    10681 aaaacatttg gacaaggaga tgcaaaataa tgacaattaa aaatttaaaa ggtgtaacag
    10741 ctgcaagcga ccaattgatg aaagctttta aagatggtaa cgaagaatct tttagcgcag
    10801 ctatggtaag cttatctaag gaaattcagg ataaaatttt agaagaagca acagcaaaaa
    10861 atcaagatca attagtatta atgaaccgtg gtcagcgtgt attaactaca caagaaacaa
    10921 aattctataa cgaagtagtg aaaaacgaag gttttgcagg ggtcgaagaa ttagtgccag
    10981 ctactgtatt tgaacgtgta tttgaagatt tagaacaatc tcatccacta ttgcaaaaaa
    11041 ttacttttgt taacacaact ggtgtaacag aatggattgt gtcacgtgga gtcaatccag
    11101 catggtgggg taaactttgc gaagctgtta aaaaagtttt agataatggc tttgatgtaa
    11161 ttaacatgaa gcagttcaag ctatcaggtt atattcctgt atgtaaggca atgcttgatt
    11221 taggtccagt atggttagat cgttatgtcc gtactgtttt agtagaatca ttgagaattg
    11281 cattagaaca agcaattgtt gatggtactg gtaaagatat gccagtcgga atgatgcgtg
    11341 acatgagcaa acaaactagc ggagaatatg ctgaaaaaaa agcagaacct attacagctt
    11401 tagatgctgt aactatgggc ggtttgatgg cgcgactatc aaaattcaat atcgaaggtg
    11461 tgaatgatcc gatttatcgt aatgtgaatc cttctgatgt ggtcctaatt gtgaatccaa
    11521 ctgattactg gtctaaagta ttcccagcta agactgtact aactgctaat ggagaatacg
    11581 tacaagtatt gccagtacca gtttcagatt tgcagtcaac ggctgtgcca gaaggaaaag
    11641 cagttattgg ggtagcctca gattacttca tgggtgtagg atctacacta aaaattgaag
    11701 cttcagatga ataccatttt gttgaagacg aacgcattta tctagctaaa caatatgcaa
    11761 acggtcaacc taaacgtaac gatagtttca ttgtattaga tattagcgct ttgggaacta
    11821 ctactacaac tacaaaacca acaaccacaa caactacaac acaagcgtag gtgatcagaa
    11881 tgaagtatat tctttgtcag ccggcaatca atcggtttaa atgggagctt gaagtttgtt
    11941 taactaatct gaagaaacta ggaatcaaag atatcgtatt gcttttcagc agacacgatg
    12001 atcagattcc tatttttttt gagaaggaat atggtgttga agttcatgtg tacgatgatc
    12061 tgcgggacga caaagagtat attccttcga ttaaaccata tttatggtgg aaatatttag
    12121 aagaagatca ttcgcgtgag gacgaccgat atttctatat cgattcggat gtcattttca
    12181 ataaaagaat taatttgcgc aaattgcctt ctaaagatga tgtttggtat tgtagcgact
    12241 gctgtagtta tctaagtctt gattatatta gaagctgtga aaacggagaa aatattctaa
    12301 aagatatggc aaacattgta aatgttacag tagaatcttt ggaaactata aacactaatt
    12361 caggaggcgc acagtgggtt attaaccgtc ctaaagcgaa ttattggaaa aaggtttatc
    12421 tggattctaa tcggctatat cgctacctta gagggcaaaa aacaaatata caaatctgga
    12481 cagccgagat gtgggcacag ctttggaaca tgatgtattt caatattggt cctaaagttc
    12541 acgaggaatt agacttttgt tttgctactg atccaataga aaaagttaaa gaagtaaaaa
    12601 tcttacacaa tgctggagta acaacaaacg atgaagattt atttttcaaa gggagatacg
    12661 tgacttctac gccttttgat gaagatttat catttgtaaa caagaaaaaa tgctcttacg
    12721 catatgttaa agcaattaag gcggtggtta gatgacgcct gaacaagtga ctgaagaatt
    12781 gctaatagct gtgaaggata atatttacgt tacctggaac gaagaagatg agtcaattaa
    12841 aaagatgata gctaaaaatg ctgtttatct tcaaagtaaa gtgagtacaa cactttcttt
    12901 ttctcctgaa agcttagaat acggattgct aatcgaaaga tgtagatacg actggaatcg
    12961 tgctttagat gagtttgaac aaaatttcgc tagtgagtta ttaggtttca ttcaacatta
    13021 tgcgctacaa gaatatattg caggtgatgt gaatggcgaa taatcgtaga ctcgaagaaa
    13081 cattcaacga tggttggtta aagattttga cgcaaactac caaaagaaat gaactaggaa
    13141 aaaagattgg tgtagaagat acagaaatca cttctttaaa atttagaaat ctttccatga
    13201 gagatagtga tataacagct atggatgcga tgggatcgaa attaactaag aaagtaaaga
    13261 ctccatttca tccaatcgcc aagaaattta ataaagatca atattttatc gtaatcgata
    13321 gtatgcgtta caacgttatc tatgccgatt acgataattt ttatatctat ttttatcttg
    13381 aaagtgtggg tgaatatggt gattgataat tctaaagaaa aagaacgttt aaataagcaa
    13441 atttctgcta tcaaaacttc cttagaagag cattttggcc tcaaactctt tcaagactcc
    13501 gtaggcgagg atgagctacc tgatgatttt aattacttca ttctcgaaac aggagaaata
    13561 gaaatgatca ctgagccaaa atatagcgtg ggtcaaaatc tatatctaac tttctattca
    13621 gaaaatagag aagatttaac aggagactca ctagatatta tttcattgat tcaaaatcgt
    13681 tcgattcgtt ttcagagaat ggatcccaat catttaaaac tagagaacca agatcgctat
    13741 atcgatcaat tggtatttac gtttagacga ttattgaaga gtgattgtca tggctaaaaa
    13801 tagttgggag ctaaaaataa atggacatga tgaacttctt gtgcggatgg aacgctattc
    13861 aagcgagagc gaacgactga ttaacgaagc attgaaatca aaaggttcgg ctattgcagt
    13921 ggataggatt acagaaaaaa ttcctgtttc tgaagcagat ttaagaagag ggcaccaaca
    13981 cgcaaaaaat agtcgtccac ttaagactca atacattaat ttgggtttca tcattagacc
    14041 tacaagaaaa tttgagtatt taaaatatcc tgatttgggg ataggtactt ctaaaagaaa
    14101 tcagccggac gaatttatga gaagaggatt aggtcttgca cttgatccaa ttacagaact
    14161 tctgattcgt caattcgata aattaaataa atagggggaa caacaatggc taaaacaaaa
    14221 actgtagtaa caacgttcga taacataagt atcaaacgaa ttgcttttaa ttttaagaac
    14281 gcaggaaatg caatcgcaac gaattgtaac ggacaattag atggcgaaac agaaatgcaa
    14341 acggtggtta aaaaatgtgg agcggcagaa gtaaaatcaa aatctaaacc aatcaatatg
    14401 acggtaacaa ttactgcaca tgtaccgatg gaagtttatc gacgtttcaa tgggttgaaa
    14461 caagatggac gtattaaacc aggcatttac tcttacggtc ctgattccgt aagcgaagat
    14521 ttctcacttg ctgcagagat cgtggatgac ttcgaagaaa atagaaagtt agttggtatg
    14581 ttagcatgca cttcgaatac aggattaaca ttctctattg aaaatggtgc ggatgaagta
    14641 gctgcgttag aactagaagc aaaagttatg caagatgaat ttggtaaatt ttatcatgaa
    14701 gcaattgttg cagaacttga agaagactta acagatcaat ggatgacgaa tctatctgct
    14761 gatgtgatta aaaaaacttc agttgtggca actacggcca ctcaatcaca gtaaaaaaaa
    14821 cggaggtagc gaaatgaacg aagattactc aaaaattgaa ctaaacgatg gaacaatttt
    14881 gaatttagaa cctaaactga atatcaagaa attattgatg atcaatagag attttaacac
    14941 agacgagttt gcaaaaatgt cgatgggaaa aggctctatg gatattacag ttattcaagg
    15001 tgcaaaagcc gtatatgtag cttatcgtca agcgaacatg gtcgattaca tttcattcga
    15061 tgaatttata gataaatggg attttgatat ggaggttgca gtagctgtat acagtactat
    15121 gatgttcaaa caagcacgtg atgcctatca aaaagaattc gaaaaagcaa ataaggaaaa
    15181 aaagcttcaa aagtaaaaat gccaaagctc ttagttgaaa cgtgggtcga tgtctattcg
    15241 atgttgaccg acgttttttc tatgccttca gatttggttt taagcgatat ctgtttagat
    15301 gacattttgc aaatggctta caacaagagc gcttatgaag gatggaagaa ctatgcaata
    15361 aatcaatccc agaaaaacta aaggaaagga ggtaaaaaat ggctaaaaag agaacggaag
    15421 cagaagtaac tttcatagct aacgatgacg gattgaaatc tacgttaaaa gaaatcagtg
    15481 ctgaattaac taaaaataga gcagaattaa aactagaaca agctcaatta caacagactg
    15541 gttctgaatc agacaagtta ggaagtaaat tatcttcttt agaaaagcag tatgaattac
    15601 aaagtcaaaa agttgaagta actagtcaac gtttagccaa tgccaaaaaa tattatggag
    15661 aaaattccac cgaagttcag aaacttgaaa gagaactgat taatcaacaa acagctcagc
    15721 aaaggttatc taatgatata gataaaacga gtaaggcatt ggctcaatct aaaggtgaat
    15781 ttaaaacgta tgagtcaact atgaaagact tagataatga gcaacaacat ctaaagtcaa
    15841 gcgcatcatt agtagaatcc gaatataaaa aatggcaagc aactgctggc cagtctgcta
    15901 cagaatctga aaaattagca aaagcacaag aatatgtcgg caaacagagt gatattgctg
    15961 aacaaaaaat cgaagtgcta aaaaaacaat tagatgccac acaaaaagaa tttggagaaa
    16021 catctaccga agctttagaa atgaaaacta agcttaatga tgcggaaaga gaattcgaag
    16081 aattaagtaa tgctgctaaa aacgttgata cctccacagt agatgatatc ggcaaaaaac
    16141 ttgatatggg taatttaatg gaagctactg atcacttgtc agtgatcgga gataagctta
    16201 ttgatgtagg tagtaagtct attgaagcag ctggaaaagc acaagctatg caggcccaat
    16261 ttaaacaagt ctttggctct ttagaagggg aagcacagga cgccgttgag ggaatggctg
    16321 aagaatttgg aatgttacca aatacgatca agcctgtttt tacacaatat acgtcaatgt
    16381 ttaaaggact tggatatgat accaaagaag ctatggagtt agctggtgat agtactcagt
    16441 tagcagcaga tgcagcagct ttttacgata agtctatgga tgatgctagt gaatctctta
    16501 attcatttat aaaagggaac tacgaaggtg gggagcaaat aggtttattt gctaatgata
    16561 ctcaaatggc agcttatgct gttaagcata atttgatacc agcgactgaa ggagcaaaaa
    16621 aagccagtga agagtcattg ttagctgttg aaaaagcaca atctaagtat gctgatgcta
    16681 ttaagaaaca tggtgaagga tctttagaag caagagaggc tgctttaaaa cttaaagatg
    16741 cgcaagataa aataaatgaa gaattaggcc cacaaacgca aaaatggtct gatttagatg
    16801 aggctaccaa gcaagcagtt cgagttcaat atgctgaaga tatgcaaaaa ttagccggtg
    16861 ctacaggtca ggctagtagg gagtctgatg gtttagaaaa ccaaatgaca agagcaaagc
    16921 aagcgttaga agatttttat gcctcattgg gtgaagatat actgcctgtg tttatcaaag
    16981 ggttgcaagc aggagcgaaa gctttgcaag gattagccga atggtggagt aaacttgatg
    17041 ggccaatgaa aaatttcatt ttagctcttg gaggaattct agcattatta agcacattag
    17101 ctcctgttat aaccgcagtt gttacgatag ttggcacatt tggttctaca gttttgctgc
    17161 caataatagg aattatagcg ggcgttgcag ctgtaatagc gattgtaatt acagcgtttc
    17221 aaaactgggg cgcaatcact gactggttta gtgatttatg gaaaaaattt accgattggt
    17281 taggtgatac ctgggaaagt ataaaagaaa gtgcctcatc agtttgggat ggagtcaaag
    17341 aaacctggtc tggatttgta gattgggttc aagaaatttg gcaaggagtt tctgattggt
    17401 ttggagagtt atggagcgga ttagttgaag gagcttccaa catctggcaa ggagtccaag
    17461 agacttggca agcattcgtt gattgggttt caaatatttg gaacggagtc aaagaagtat
    17521 ggtcgattat ttgggcagac attgtaggaa ttgttcaaat accatggaca ttaataacgt
    17581 cattgattca agctggtatt aatattatcg tgggtatttt tgatgtagct ggacagttat
    17641 taggcgcagc ttggcaagct gtttggacac ctatttctga tttccttaaa aatacttggg
    17701 atactatgac acaatggata agcatcgctt ggaatggaat tgtaactaca ttccatacta
    17761 tatttgatcc agtagtggca tggtggaatg gtatatggac atctattagt actacggctt
    17821 caaatatttg gaactcaatt agtgcaacag cttctagtat ttggaatagt atcaagaata
    17881 caatcactag cttggtacaa gcagctgcta cagtaattca aaatatttgg tcaactgtat
    17941 ctagttggtt aggtggaatt tggaattcaa tcagctctac agcatcaaat atctggagta
    18001 gcgtgactag cagtataagc aatgctataa acgcagctaa aagtgccatt caaagtgttt
    18061 ggaatagtat atcttcgtgg atcagcggaa tttggaacgg tatcaaaaac actgctttga
    18121 atctttggaa tggaattaca agcactatta gctctaaagt aaacgatgga aaaaatgcaa
    18181 tttcaagcgg ttggtccaat ctaacaggta ttgtttccga catattcaat aatgttaaaa
    18241 gcacgatagc taatatatgg gaaggtatca aaaagactgt tagcgctccg attgattgga
    18301 ttagagataa aatcagtagt gtctttgata atttgaatat ttcgatacca catattccgt
    18361 taccacattt taaattgagc ggagaattca atccattgaa ggggaaaatc ccaacattgg
    18421 gtgttgattg gtatgcgaaa ggtagtgtgt ttaattctcc aaatattatc ggtgtcggtg
    18481 aagcaggacc tgaagcagtt ttacctttga aaagatctgt gctgcaagaa attggggatc
    18541 gtatcttgag tagcacatca gtttcatcta gggcacaaac gattcaacct gtgaataact
    18601 acgaattcaa tttcacaatt gatggtaacg cagatgaggt tactatgaag caaacaactc
    18661 aacaaatcat tgatagcatt acaaaagttc aaaatgataa tgcttcggca tggcgttaaa
    18721 caggagagta tttctcctgt ttttttagtt ttaaaaagga tgtgaaaaaa tgactgattg
    18781 tatacattct ataatcgatg gatttcctga ttatttgcat aaattggctt tagcggaaag
    18841 accaaccata ccttctccaa aaagacagag agttgaaact tctgttttag gacggctagg
    18901 tggcttagta caagattact cgtttgaaga catgtcgttt acattgcact ataactattt
    18961 agaagatgtg gaagaccatc aagcattcaa gcaatcgttt tatatcatgc gtcattggtt
    19021 aaactatgca aagaaattag aattctctga tgatcccaac gtctattatg ttatccagac
    19081 tatcgatatt ggggatgcag aaaacgatat tgttgaatgg ggagagttcg atgtaaatat
    19141 cactgcgaaa ccattcgcaa gagttcaaga agatgtacct ataaccgtag ataaaccaca
    19201 gtcatttaac ttgctgaata atagtttaga agaaagtttt ccaaagatta tcatcactcc
    19261 ttcagctact tcatgccaat tcaccttaaa tgattatgtg tttagttttg aaggcttagt
    19321 agtgggaact gacatagtca ttgatagtga tttgatgctt tgctacgaag agcaatcgga
    19381 cggagatatt ttagatcggt ccaacaaaat gaagaccatg caatatccaa cgttgcaagt
    19441 ggatattaat cattttaatt gtactggttt gagcaaaata caaatttatc gtaatgggtt
    19501 aaggtaggtg aaatagatga tcgataattt actaactatt tacgataaaa atgacgcgaa
    19561 taatttagct gaacatttat atgatacgca aggtttaggc gctttgtcag actggttaac
    19621 agctactgtt agcaataaac taaacggagc cgagatattt cagggtactt attcaataaa
    19681 cggaactaat gcagatttga ttgtagaagg acgtattatt cagtgttatg tagatgaaaa
    19741 tcgagcaaaa cagcgtctac ggatttatta tgcaaaaact tctgtaatag gcaatacgat
    19801 agaagtaaaa gctgaaccta ttttcaatga tataagaaaa tcggtgttga ataaatatga
    19861 cagcggaaca gaaaaaatca ctgctactca ggcatggcaa aacgcaaaag ttttagcgaa
    19921 accagctatc ccttcgcagt tttctttctc gtcattagta gatacgcttg ctaatgtgaa
    19981 gatagaaaag gcgaattttt tagaattctt tggtggaaaa gagggatcta ttctagatcg
    20041 atttcatggt gagtttctaa aagataataa cacattacgt catgaaaaaa gtctaggtac
    20101 ggatcataaa atcaaagcga tttatactaa aaacttaact ggtcttgact tagagattga
    20161 tgctcaaagt gttttagttg gagtttatcc attcattagc agctcttcag aaggagaaga
    20221 cgagatcact ctaccagaag aagttatttt cacggattac gtggatgatt atcctgctgg
    20281 atatgtttct tttgttgatt ttaaagacaa agcgactgat gtagccacat taagggaagc
    20341 tgctaaagac tggttgaaaa caaacataga taaacaaaaa ccacaagtga gtggttcgat
    20401 tgaattagta ccattgaggc atcaaagagg ctatgaaaaa tttgttgatc tagaaaaagt
    20461 ttcgatgggt gacggagtag atgtgtatca tccacagtta aaagtgaata tgtcagcgag
    20521 aattgtggaa tatacgttta atgttctaac caattcatac gataaattag ttgtaggaaa
    20581 cgtcaaaaca aacttcttag aaaacacaga gaataatgta agcaatttga ttaatgattc
    20641 cattgatcaa ttgaaaaatg gtggcgaaat cagtgattta atcaatgata ttgtagatca
    20701 tcaaactgat atgattactg gtcaaaatgg tggttatgtt ttattagatc ctaaagaagc
    20761 gcctagtcgt attttgatta tggacacgcc agataagaat accgcacgga atgttttaca
    20821 aatcaacaac gctggtattg gtttttctaa aactggtatt aatggaacat atgaaaccgc
    20881 atggacgtta gatggcggat tcaatgcctc gtttattaca gctggtgaga tagtagggat
    20941 tactattaga ggtactacat taattagtga tggtgctgat tatagaacaa gtatagctaa
    21001 tggcaaaatg acttggtact caaaaaaagt taacaaagat attatggagc tagaagcacg
    21061 tgattatgta agtgctgatg ccggtattgt atcatacacc atgaaaactg gtggtggttt
    21121 catgattaga aatccacagg gtaacttggt ttttagtacg tgggataatg gtaataacag
    21181 accgtttcta tcttttggtg cgcccaattt caggtatagc aatgctagtt atgtaacttc
    21241 tggcgacggt agttctttaa gcattaatgg tagtgcgggt aactcatggg aatttaaggt
    21301 agctggtagg actatgaaat ttactagtga tggtatgcta acgttaccag gttgtttttt
    21361 tggttcatgg gaagatggga aacttgctag gtttgaacaa tcaacggtac aagtatataa
    21421 agattttact gttagaggta ctaaaaactc aactgtacca acagaacatt atggacaacg
    21481 actattgaac gcttatgaaa ctccagaata ttatttcgct gattatgggg aagccgttac
    21541 aggtgacgat ggtaaagttc gtgttgatat tgaccccatg tttgctgaga cagtaaatct
    21601 aagtcggtat atgacacatg tgacacctac agaactagtt ttgtgtgctg ttactcatga
    21661 agatattgac catttcatca ttgaaactag taagccaaac gtattagtta gatggaattt
    21721 agtggcacac cgtctagggt atgaagatat tagattaaaa gaggatacag catatgatag
    21781 cacagtgctt gaccaaaaac gtttttaaaa cgaagacaag gaggtatata aatggctagc
    21841 agtttatata atttggcttt agatttcagc aaagaattaa actacaccaa agctattatg
    21901 gctcgtcagg gtgataaagg gattacggtg acggttaaac catatttaaa tggcttgcag
    21961 atggatacga gtggcggaac atttacttta aaaggaacaa caccatctaa ccgttacgta
    22021 gatagtgttg caactagcgt aactagtgaa gaagtcacgt tttctcttga tggcacattt
    22081 atgagtgaag caggatatta taaacactgc tacgtagaat atagaaaaga caatcaaatt
    22141 ctaacaacgc aagatatcat ttttttctca ctaggagtgt ctgacatttc gcaaggtcaa
    22201 gccgatgaat atgtttcgca attagaagag ttgattcgaa agtataatga aacttttgat
    22261 gcttttatgg ctgaaactaa aggtagagtg gatagcttaa atcaacagat tactgattta
    22321 actggtcaag ctaaaacgct acaagacaag ttagatgctc tgaaagaaga aatttctaag
    22381 ttaggtaact tacaagtgat gtacagtaac agcatcaact ttggtgacta tgattatagt
    22441 ggaaatccta atttgttaag taagctatca tacgacttaa ttgaaaatca aaatacttca
    22501 gctggaacac tttctaaagg tgaaaactcg tttaaatata ataagatatc agctgaagtg
    22561 gaaggtggag tagagctata ttataaacga agaggtatag ctaactggct accatctaat
    22621 aaaacgcttg taatgactgt taagcttaga gctggagcgg actatagtcc agttgacgga
    22681 aaacttatac tgattagata taggtatgtt gacagtggaa ctggcaagat tgttttagac
    22741 ttacctatta acagtaattc gataactcag gaatggaaag agtttagtat tactggaact
    22801 actccaacat ttagcccaca agcataccat ccttggatac aatttagggc tcaagatggg
    22861 atacttgggg aaatagaaat gagctatgac atcaaaatcg aagaaggctc aacagctaca
    22921 ccattccaac ctaacttatt agcagaacct tacaacatgt gtcgcgaata tcctaacgaa
    22981 aatattgccg atcatacagt taagttccca atcgaatctg gcgaccacca aatatatcaa
    23041 ggttacacag aagaagagct tatgataggt caaacgtata ctatcacgct taaaggaaca
    23101 aaacccgcaa gtcaaacctt tgtagcgtat aatcattgga ctgctcgttt aggagaacta
    23161 aagccagttg atgggttgac agacgtatgg tctctaacat tcacaccaac gaatgttgtg
    23221 gcgagttcac ctaaactttt tcgtgtttat cagtatccac aatcaacagt aggcgcatgc
    23281 cggatcgact ggctcaagat tgaaaaaggc gacacacgaa ccccgaatat tagtgagtat
    23341 aaatatcgtg gtactggtat gcgtgattca aacaatccaa aagattatgt ttgggatcta
    23401 gcaccagaat atgtcgaaga taacttggcc acagatatta aaatttctga aattactggt
    23461 aaagcaaaca attataccga tgggaaagta tcggagatta attcgcagtt gactgcttca
    23521 attaatgaag tagacaccac agctaaggat gctcaaacaa aagcgaatgc taatgcgact
    23581 gctatagatg aattagacaa taagatcgat gaacgcatta atgatacagc tactaccaca
    23641 ttaacagtta caaacgggaa taccggatca gcaaagcttt atcgtgaagg aaaaacagtt
    23701 tctatatatt ttgtggcttt aaacggaaaa agcagtggtg gaaatgattc aacgatacta
    23761 acaattccag aaggctatcg gccaccaatt agttttgagc aactggttgg ctcgatagac
    23821 cgttctactt tgaacagtgc tcagttatct attggtgcag atggagccat taaatggcga
    23881 agaaactcaa gttatggatc ggattatacc tttgcaatta cttacacgat ttagaaaagc
    23941 gtgaatcgat atgaaggcag catatagacc aattgaacct tacggattcg agcaaatcat
    24001 tgtgaatgat gaagaacatt taccggaaga atgcacagaa gtcgaaccac cgattccaaa
    24061 ttggaaaccg aaattcaatt actgggaggg aaataaatga aaaacatttg gaaatatgga
    24121 cgtactggcg gagagtacgc aggaaaagta ttggacgaca tgcttgtatc cgttccttac
    24181 acagatcagc caccgcttga aggaattcgt gctgatggcg aaccgttaac aatcgctgat
    24241 caaatgtttg atcctaaatt gaatcaatgg attattttag cgaacgcact agatcacaac
    24301 gatttaaaca atctcaaagc aatgtatgag tcgttagaaa atgagaacgg cgatttaaaa
    24361 cagatcaatg ccaaactcat gctaagcgat gtagcaatta aacaggaaaa tactgcattg
    24421 aaagaaaaag cggatagttt agcacaaatc aattcaaaaa tgatgcttgc ttcgttacaa
    24481 aatagcaaag acatttcaga aattaaagag caactaaatc cagcttcaaa gggaggtgag
    24541 tagtatgttt agttttagcg atgtgaaaat gatgtatgat tggggctgtt tcactaacga
    24601 acaagtaatg gttttcgttc cgttgtgcat tactgaagaa gaagcagata aaatcattag
    24661 caaagaagag agcgcatctt aattgatgtg ctttttattt tgattcaagg agttgtcaca
    24721 tgattaattt aggggaatgg ggagcgatag caggatcaat aaccgctatc gtttctttga
    24781 ttttattagt aataaaacca attactgcat ctttctcgaa gattactgag actctttcaa
    24841 aagtaagtca caatttagat ttgctgacta aagatttaga atcgagcaaa tcagatcgat
    24901 tgatgattca tgaagaacta aagaaacacg atgaaagatt agatacacat gcagaaaaat
    24961 tggtagaaca cacgcaacaa attaaaactt tatttaggga gagaagaaaa tgaataataa
    25021 aacgttcgaa gtactaaaat ggttcgcact ggtaattatt cccgcactag ctactttcgt
    25081 ggggttagtt ggtaaagcgc tcaattggca gtacacagat atctgtgttg tcatcattac
    25141 tggttttggc gcgtttttag ggagtgtgtt gggtgtatca aatcgaacct acaaaatgtt
    25201 ctcggctgaa agcgaagaag gaggaaacaa atgaaaaaga aaattactat tactgcgatg
    25261 agcctgttaa cggctctttt tttattaccc attaatacgt ttgcttatac tattaatgac
    25321 gagtataatt tagcgccgaa tcaaggagac tccagattag caattcctaa caaaattatt
    25381 ttgcacgaaa ctggaataga tgcaccagca agaaacgtag ccgccaacat gaaaaataat
    25441 tataacggaa gcaatcctta tactacagat gttattggtg acggtgggat tgtttaccgt
    25501 gtgggtgagc aaggatatgt ttcgtgggga gctggtaacg ctaatcctta tgcgcctgta
    25561 cagattgaat tacagcgcac atatgataaa gcattgtttg aaaaaaacta tcgagcttat
    25621 attgaatata caagagatag tgcaaaaaaa tatggaattc cattgactct tgatcaagga
    25681 acttctttat ttacaaaagg aatcatttct catttgtggg tgacaaatta tgtttggggg
    25741 aaccacacag atccatatgg ttacttatcg caaatgggag ttagcaaaga aaagcttgct
    25801 tatgatttag ctcatggatt taccgatgaa aatccaacaa cttctgaaaa caagcctgtc
    25861 attgatccaa cacgagctgg tgcagctaat cctacgctga cagatggaac aaatcacgcc
    25921 cacattgatc agtttgggga aatcgaaaac gcaaacttgc atgtggctgg atggcacatt
    25981 gctaactata aatacgagta tattttcatt atggactaca atactgggaa agaattagct
    26041 cgagtaagag ctgatggaat ttatagacca gatgtaaacc aagcttataa tacttctgga
    26101 aatgttggtt atcatgtatc tttcaatatg cgtaattttc ctagtaagaa agtctatgta
    26161 atgatgcggg caacgaatga tccagaggga aacactaaag gcggtgcgca agatttccat
    26221 gacaaacgtt ggtatttaaa tattcctaaa cgataaaaat agctcctcgt tgaggagcag
    26281 tacataacta tattgacaac tataaaaatt attcgataaa atagtgatgt tatcgcatat
    26341 cttcactatc acccataaat agtcacactc caagctatgc gataacaggt ttgttgccac
    26401 acattctact ggttgattgt ttatggcttt atgtggcaac aacc
//
LOCUS       DACGLI010000043        25771 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.044, whole genome shotgun sequence.
ACCESSION   DACGLI010000043 DACGLI010000000
VERSION     DACGLI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.044"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            420..974
                     /locus_tag="IXT22_001957"
     CDS             420..974
                     /locus_tag="IXT22_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4863299.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1147..1620)
                     /locus_tag="IXT22_001958"
     CDS             complement(1147..1620)
                     /locus_tag="IXT22_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4863300.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1632..2168
                     /locus_tag="IXT22_001959"
     CDS             1632..2168
                     /locus_tag="IXT22_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4863301.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            2208..2579
                     /locus_tag="IXT22_001960"
     CDS             2208..2579
                     /locus_tag="IXT22_001960"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4863302.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2863..4134
                     /locus_tag="IXT22_001961"
     CDS             2863..4134
                     /locus_tag="IXT22_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAQ4863303.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4379..5404
                     /locus_tag="IXT22_001962"
     CDS             4379..5404
                     /locus_tag="IXT22_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863304.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5698..6807
                     /locus_tag="IXT22_001963"
     CDS             5698..6807
                     /locus_tag="IXT22_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863305.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6890..7786
                     /locus_tag="IXT22_001964"
                     /pseudo
     CDS             6890..7786
                     /locus_tag="IXT22_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7802..8626
                     /locus_tag="IXT22_001965"
     CDS             7802..8626
                     /locus_tag="IXT22_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863306.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8658..9968
                     /locus_tag="IXT22_001966"
     CDS             8658..9968
                     /locus_tag="IXT22_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAQ4863307.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10116..11375
                     /locus_tag="IXT22_001967"
     CDS             10116..11375
                     /locus_tag="IXT22_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4863308.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11385..12257
                     /locus_tag="IXT22_001968"
     CDS             11385..12257
                     /locus_tag="IXT22_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863309.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12269..13099
                     /locus_tag="IXT22_001969"
     CDS             12269..13099
                     /locus_tag="IXT22_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863310.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13139..15322
                     /locus_tag="IXT22_001970"
     CDS             13139..15322
                     /locus_tag="IXT22_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4863311.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15383..16603
                     /locus_tag="IXT22_001971"
     CDS             15383..16603
                     /locus_tag="IXT22_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAQ4863312.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16600..18060
                     /gene="gtfA"
                     /locus_tag="IXT22_001972"
     CDS             16600..18060
                     /gene="gtfA"
                     /locus_tag="IXT22_001972"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAQ4863313.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18137..19243
                     /locus_tag="IXT22_001973"
                     /pseudo
     CDS             18137..19243
                     /locus_tag="IXT22_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19565..19774
                     /locus_tag="IXT22_001974"
     CDS             19565..19774
                     /locus_tag="IXT22_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4863314.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19951..20735
                     /locus_tag="IXT22_001975"
                     /pseudo
     CDS             19951..20735
                     /locus_tag="IXT22_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(21019..22104)
                     /gene="xerS"
                     /locus_tag="IXT22_001976"
     CDS             complement(21019..22104)
                     /gene="xerS"
                     /locus_tag="IXT22_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAQ4863315.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22438..22671
                     /locus_tag="IXT22_001977"
     CDS             22438..22671
                     /locus_tag="IXT22_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAQ4863316.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22668..23075
                     /locus_tag="IXT22_001978"
     CDS             22668..23075
                     /locus_tag="IXT22_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4863317.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(24212..24730)
                     /locus_tag="IXT22_001979"
     CDS             complement(24212..24730)
                     /locus_tag="IXT22_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAQ4863318.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         8781 a         3926 c         4793 g         8271 t
ORIGIN      
        1 caaaattatg atcttgcgta aagttataaa atattaataa aaatatttta ttaatgaaaa
       61 gcttggtagc acggttattc atatgctaat ttatttcact ttatagtaag gggagttctt
      121 agtatattgt tcaaacttaa atttcatata atttaattat gtaaattagc tattctaaga
      181 acttctacgg ataactgccc gtctaaaatt taaataagag cttagaatct tcatataagt
      241 aaggttaatt tttttgtaca aaaaagtcgg aatattctga gttactgaaa tgatataaaa
      301 tcataaacta aatcccttga ttttattgac tttcaaaagt ttatatatat aagttaatga
      361 ttatggtaaa atatatacat aatcattaac tcagaatatt tttaagaagg gaaacaatag
      421 tgagctataa tgtacaaccg ttaaggacaa atgaagagat acaagatttt cagttttggc
      481 taagaagaac aagtaatccg gaaagagata gttttttatt tttgtttgga atcaataatg
      541 ggttacgtat gtcagatatt ataggattaa aagttggaga tatacgaggc aaaagtaagc
      601 ctattattgt tgaacataaa acaggtaagc gaaaaccgat ttttatagat aatttgagag
      661 aagaaatttt attatatact gaaggtaaag aagaaaatga ttggttattt ccgagtcggc
      721 aacaaggtcg acatataaca agggatcgtg tctatcagat atatgcagat atagcagaaa
      781 aattaggacg agatgatata ggaacacata cattaagaaa aacttttggg tatcactact
      841 acaagaaaac tagagacatt gctaccttaa tgtttatttt taatcatagc tcgcaagcaa
      901 ttacaaaaag gtacattggt ataactgaag atgaaatagg agcatcactt cgtggattta
      961 aactaggtgt ataatttaaa aatttttata aacagtaaag acaaagatta aaagctattt
     1021 ttatctagaa cgattttatt tcataaagtt cgcggaataa aagctggggt tactggtact
     1081 tggtataggt tcgtgttata taaactaagt aattaaataa catttttagg ttggaaaagg
     1141 atgaaattaa aaaaagagaa tcaatacggt ctcaaaaacg caaacgctgc ggaataagaa
     1201 aaatactgat aactcaacgt ttagcagact atctaatagg gatagtctgc ttttttcgtt
     1261 tttgaccata cttttgacct tctgcaaact tccttgcttt tcctctgtag aactcatgaa
     1321 atctgcaaaa cgaattgccg tttcctctgt ctgctttttc gcgatatggg tgtatatatc
     1381 atccatagtg gttttaatat ctgtatgtcc aagtcgaaca tacacttctt tgacagacgc
     1441 accagattca aagagcagac tacaatgggt atgacgaaaa ccatgaagtg tgatatgttt
     1501 taagttattc tctttaatga tgattttcaa attgtgattt acatagtcta aataaagggg
     1561 cttattttct tctgatgaaa acaaaagttg ttcaccatct tttataggtt tgattctcat
     1621 ttttagatat tatgcccgca cgtattcatc acatttctat tgtgaatcgc tttattcgac
     1681 cgacatttga cttttatcat aatatactcg gtttaaaatt actaatgaaa acaattaatc
     1741 aagacgatca taccatgtat cacctgtttt tttcagataa tcaccaccgt gtgggaactg
     1801 aactgacttt ttttgaagta caagaaggga acaaccagtt ttttggaacc aatacgattg
     1861 aacgaacgat actaaaagtt ccttccgaag catcattgca tttttgggaa atatattttg
     1921 aaacacaagg cgtttgccat tatggaatcg aatcattttc tggacgacct atcttacgtt
     1981 ttgaagggcc agatgcaaca cgattagctt tagttccctt acgcgaattt gaagatattg
     2041 atgattattt cccgtatgtc acagaccaga tccctacaga gcatgccatt ttaggaattg
     2101 atgccattca actacgcgta caatattccg atgcgactga acgagagtta ttgtcggtag
     2161 gctggtagca caaagaatac gtcagtttct tttcgggtca tcaacgagtg acaatcttag
     2221 aaaatcaaga cactcagttc tatcaagaag ttcagattat tcaagatcgt gagaatccag
     2281 ttgccattga agggattggt agcgtccatc atgttgcgtt tggcgtagaa aataaatctg
     2341 atttacaacg catcgacaaa caattacaag agcgcaattt tataaattca ggaataaaag
     2401 atcgtgaatt ttttgtatca ctttattatc gtgacccaaa tcaattattg attgaaattg
     2461 ctacagggga aggaaaccta gatgcaaaag cgtatgaaaa tcaaagtcca cgctttgaag
     2521 aaattccttt atttttaccg cagtacttaa atttcattcg tgaacaagtg gagcaataat
     2581 tagctaatca aatccatgac gaagagtaag aggttgactc ataagtcaaa aaataaagaa
     2641 aaacgcatca aatccattct aaagaatgtt gatttgatgc ggttcctatt tttataaact
     2701 atcattttcg actaataaaa ctacttatga gtcagcctct ctttttttct tgatttttat
     2761 acctctttct aggtaaacta aacatctgcc aaaaataccg tgtctcattg aaacattctc
     2821 aactatttca aaataaaggg gagtaccaaa tgaacgagta tattgaaatt atccacgcaa
     2881 gagaaacaac ttaaaaatgt cagtctcaaa attcccaaaa ataaaattag tatttttacc
     2941 agcgtatctg gttcaggaaa atcatcgatt gtttttgata ctattaccca agaagctggt
     3001 cgtcaactga atgacaccta tgatagtttt acccgtttat ttttacctaa atacagtcgt
     3061 ccagaggttg atgagattga taatctttct acggcgattg tggtcaatca aaagaagatt
     3121 ggtggcagtg cgcgctcaac gttagggacg attactaaca tcaatgcgtt atttcgtgtg
     3181 ttgttttcat gttttgcaac acctagttta ggatatgcaa atgcttattc atttaatgat
     3241 cctagtggaa tgtgttctgt ctgtcaggga atcggtaaga cgattgcatt tttaatagga
     3301 ttgctttatt tttcggctat tgataatgct gattttgtat tttctgatcc atttaccgca
     3361 gaagttttgt ctggaattga ggaacaggca aagaatcatg gttattttgt attggtgcat
     3421 aatgttaatt cagcagaaga tgttaaaact attcagagaa attggcgttt tgaggggttc
     3481 attgttgttg gtgtacgtgt aaaagaattt ttggaattaa ataacgtttt tgatggtcct
     3541 gttgtttata ttgatacgca tctttcaaaa gagacattaa gagaacttga acaacaaatg
     3601 aatcgtttat ttgtaaatac aaatgattac caagctagta cattggcagt ggaacatttg
     3661 attcattatg gtcatgagaa aatagcgttt ctttcttttg actacattgt aggtgaacca
     3721 agtgttattc aagaacgaca tcaagcttat atcgatacat taaagaaata tcatttaacc
     3781 tttaaatcgc attggatata taacaactct gaatttgagc gaatttatca agaattagct
     3841 gaatttactg caattgttgt tactggagat tatttagcgg ctaaattagt aaaattttta
     3901 aaaaataaga ataaacgagt gatggaacaa ttatcgatta ttggatttga tgatattact
     3961 tttgcagaat taatggatcc tgcgttgaca acaatacgac taaatccagg taacaagggg
     4021 gcgattgctt ttcaccaact gattggactg gccaaacaag aagaaataaa aaatcaagta
     4081 ctactattag agggagaatt gatttctcga gactctgttc acaaaatcaa ataaaaaagc
     4141 tctgtgaaat aagtatagtt aacaataaaa tatccgaacg atagagagaa tgaactgtga
     4201 tctagcagtt cctcgtcgca aattcactag aattagcatt atttactcta aattgttcgg
     4261 atattttttc ttgtttttaa ttatgattac agtgcctatt tttaacgaaa tttgcttatt
     4321 ttcaaaatgt atgattatat gttagtaaac actttcaaat atgaaaagag gagctattat
     4381 ggtaggaatt agggatgttg caaaacgggc gggtgtgtcc attgcaacag tatcgcgcgt
     4441 gctaaatgag gatccgacac tttcagtaac cgatgaaacc aaacgaaaga ttgcagaatc
     4501 ggttaatttt tatcattatg tcaaaaaaag tcccgttgca aaaaatttaa caaatattgc
     4561 attaataacg acagtttctg aagtagatga gttggaagat ccctattttc gaacgattcg
     4621 cagagggatt caagtcgaag cagaacaaag caaagtcaat ttgaagaaaa ttattcgttt
     4681 gtcagaaaca ccgttggagc aagacgattt gctaaaatgt caaggtgtgt tgattattgg
     4741 gcaggtgcta tcttctgtga ttgaagaagt atcagcaatt aattcgaatg tcgtagtgat
     4801 tgatgaccct agtattgaag ctgaagtaga tgcagtttat actgatttaa caaaagcaac
     4861 gaatcagcat ttagatcgat tgtataaaaa aggacaccga aacattgcgt ttatcggagg
     4921 aggacgtgtt cgtttagata gccaaggaaa taaacacgtg tcagatgatg attatcgaaa
     4981 aatagcctat gagacgtgga tgaaacaaaa aggattagaa aaatatagtc aaatttattt
     5041 agaaggctgg accacacttg acggaatgca ggcagcagat ttacttttga aaaaacatgc
     5101 taaagataag ttgccgactg ctatcatggt aggaaatgat cctattgctg tgggggttta
     5161 tcgttcactt caaaaaaatg gtctacatat tccagaagat atttcgattg tgagttttga
     5221 taatattgaa gttgctgaat ttttaacacc tgcattaaat acggtgaatg tgaatacaga
     5281 agaaattgga aaactagcag ttcgcatggt taatgaacga ataaaagaag ttagaaatgt
     5341 ttcgatcaaa gtgattgttt ctaataatat tattgttaga gaaagtgaaa aaaatatcga
     5401 ttaaaaaagt aaacatccaa aaaagggtgt ttactttttt gtttactaat atttttagta
     5461 aaaaatctcg acaaaacatt aagtaaacag ttatggtgtt gttaacaaaa agaaaacgca
     5521 ttcaaaacag gaggaattaa gatgaaacat ttcaaaaaaa tagctttaac agggatagct
     5581 gttttaactg ggacattact cgcagcatgt ggtgggggag atagtaattc taaagacggg
     5641 caagtaactt taagctatgc gagttgagat actgaccaag ctccaggact aagaaaaatg
     5701 ttagatgaat ttgaaaaaca aaatcctgat atcaaagtag aaatggagac aacgccttgg
     5761 gatcaatatt gggttaaatt agaagctgca acaacgggag gtaatatgcc agatgtagta
     5821 accatgcact ctagcgaatc ctataaatat atgtcacaga atgctttgat gggacttgat
     5881 gatgttatca aagaaaatga tattgacatg ggaaacttta ctgaaggaat tgctgatttc
     5941 tatacgcttg aagacgaact atacgcaatc cctaaagatg cttctgtagt ggggctatgg
     6001 tacaacaaag aattatttga taatgcaggt gtcgattatc cagatgaaac atggacatgg
     6061 gaaacactca gacaagctgc aattgattta acagatgaat caaaaggcat ctatggtttt
     6121 gcatcacata ttggaacaga gactggctac tggccattta tttatcaaaa tgggggagaa
     6181 gtatttgccg atgacaatac aaaatcaggt ttgaataccc cagaagcaca agaagcttta
     6241 gctttttatc gagatattgc acttgttgat catgcttcac caacaattac agaattacaa
     6301 gatcctgata agttaagtcg ttttcaatca ggtagattag caatgatgat tgaaggaaac
     6361 tggtttgcac cgggattttt gaaaaatgac tatctagttg aaaatgttgc ttctgccgtg
     6421 ttacctaagg gaaaagttaa tgcaacaatt acaaatggac ttggttgggc tgccagtgcg
     6481 agtacaaaat acccagaaga agtgaaaaaa ctaatggcat ttttagctag tgaggacgcc
     6541 aataaaatcc aagcggaaac gggggcatca atcccagcac taaaaggctt tgaagacgag
     6601 tgggctgctt cttcagatac aattgatttg agtgcttttg gaaaaatgtt ggagtatgga
     6661 gtccctcgtc catacaataa agatggatta cgagctgaac aagcagaagt tcaaattatt
     6721 aaccgtattc tgtctggtga agtaactgtt gaagatggaa ccgctcaaat tgaaaaagaa
     6781 gtcaatgcga tattgagcgg aaattaaatt agttaattat acaatataca ggcgaaagga
     6841 ttctatttcg tctgtatatt aatggatgaa taccaaaaag ggggatatta tgaaaaatcg
     6901 aatttttgga aaatatcgta aagatcaagt gatatggggc tatattttta tttttccaac
     6961 ggcattagga ttaattttat taaatatatg gccagcaatt caaacagcaa ttttaagttt
     7021 tcaaaaaacg gtagggttcg gtgatactga atgggtcgga ttaagaaatt accaaaaaat
     7081 gtttgcagac ggtgaagttt ttcagtcttt attaaacaca ttaatttatg cagtggtttc
     7141 gatacctagt attgttgtat tatccttgtt ggtggcagtt ttaatgaata gaaaagttaa
     7201 aggattgtcg atttatcgga caatttattt tctaccagtc gttgctgcac catccgcagt
     7261 cgcaatgatt tggcgctgga tgttcaataa tgattatgga ctgattaata acatgttggc
     7321 taaaataggt ctcgatggac cagcatggtt aacggatcca tcgattgcga tttattctat
     7381 tatcattgta ggagtttgga gtgctattgg ttataacatg gtgttattac tagccggctt
     7441 ataagaaatt cctaaagatt attatgaagc agcggaaatt gatggtgcta gtccaatcca
     7501 gcagtttttc aacattacgt taccattagt tacaccaaca ttattttttg tagttgtaac
     7561 aacagttatc aatgctttcc aagtatttga tgttattttt atgatgatta ctcctaatag
     7621 taccgccatg tttaaatcac aatcattagc ctatttattc tataaacatt catttatttt
     7681 aaatgacaag ggatatggtt cggcaatcgt tatgttcctt ttagtgatta tattaattat
     7741 tactgcaatt caaatgaagt tgcagaaaaa gtgggtaaac tattaaggag gctatcaaat
     7801 tatgaaaaat aaattttttt caaatgcgcc aatccatatc atgcttattt taggtggtat
     7861 tgcaatggca ttacctttta tttggatgat tttaacttca gggaaaacgt tggttgaatc
     7921 tacccaaatt ccacctacaa ttttccctga gaaatttcag ctaagtaact atcaacaagt
     7981 acttgattta ttaccattca tggcttttta tatcaataca tttttaatgg ttgttggacg
     8041 agtgattggc tcggttttat tttcagcaat ggctgcatat gcttgtgcgc gtctaagttt
     8101 tccagggaaa aatatccttt tcagcttagt acttattcaa atgatgattc ccggttccat
     8161 ttttattact ccacagtatt tattagcaca aaaattgggt attttaaata caattccagc
     8221 attaatatta ccaggggtag ttagtgcgtt tggtacgttt ttattaagac aatttttctt
     8281 aggtttacct gatgaattgg aggaagcggc ctatttagaa ggtgccaata tttggacgat
     8341 ctttttcaaa attatgttgc cgcttgctaa atcaggattg gttgcacttg gaatattcac
     8401 agcgttgttt gcatttaaag atttaatgtg gccattgatt gtcaatactt caattgataa
     8461 gatgccttta gctccgggat tagcaaactt acaaggacaa tatgccacga acttcccaca
     8521 attaatggca ggttcgttat tagcaatttg gccaatagtt gtgatattca tcgttttcca
     8581 aagaaaattc attgaaggaa ttgctacaac aggtagtaaa ttataaaact attaattagt
     8641 gattggagag taagtacatg acaaaaatta catttattgg tgcaggaagt actatttttg
     8701 caaaaaacgt attaggcgat gcgatgttaa ctccaagtct acaagatgca catattgcat
     8761 tgtacgatat tgatgaaaaa cgactaaaag aatcaaattt aatgcttaaa aatattaata
     8821 aaaattcgaa tgaaaatcgt gctgatattg tttcttatta tgatcgcaaa gaagcgttaa
     8881 gagaggctga ttttgttatc aatgctattc aagtgggtgg ttataaacct tcaacagtga
     8941 ttgattttga tattcctaaa aaatatgggt tgcgacaaac tattggtgac accatgggga
     9001 ttggtgggat ttttagaacc ctacggacac taccagtaat gttagacttt gctaaagaaa
     9061 tggaagaagt ttgtccaaat gcttggttat tgaactatac aaatccgatg gcgatgttaa
     9121 ccatgggtgt tttaaaagcg acgagtatta agactgttgg tttatgtcat agcgttcaag
     9181 tatgcgtacc agaattgttt gagcatttag gaatagccga tcaatatgac ttaaatgact
     9241 ttcaatggaa aattgcaggc attaatcata tggcattctt gttggaaatt acaaaaaatg
     9301 gggaagattt ctatccaaca attcgtcagt tagctgcaga aaaaccaaat ccacatccag
     9361 attctgtacg ttttgaattg ttgaaacgtt ttggttacta tattacagaa tcaagtgaac
     9421 acaatgcaga ataccatcca tactttatta aatcaaaata cccagaattg attgacgaat
     9481 tagggattcc gttggatgaa tacttacgtc gttgtgaaca acaaattaat gattgggaaa
     9541 gcatgcgaga ggacattgta aataatgggg agttaacaca tacgagaagc cgtgaatatg
     9601 cttcatatat catggattct attacgacag gaactccgtc agtgattgca ggaaatgtct
     9661 taaataaagg cttaatcaca aacttaccga cagatgtttg tgtggaagta ccttgtttag
     9721 tcgataaaaa tggcgtgcaa ccaacctatg tcggtgaatt gccaacacaa ttagctgctt
     9781 taaatcggac gaatatcaat gttcaagaac tgacagtaga agccgcttta acactagata
     9841 aatcaaaaat ttatcaagca gcgtatttag atccacatct atcatctgaa ttgtctttaa
     9901 cagatatcaa aaatttagtg gatgatttaa tcgaagcaca tggggactat ttacctgaat
     9961 ataattaaaa agaagctgaa agagtaagga attttcaatt ccttactctt ttcttagtta
    10021 aatttagtaa aaatattgac aaaacactta gtaaacagtt acattagtgt taacaaaaag
    10081 aaaacgcatt caaattgtat aaggaggagc ataaaatgaa gtggtctaaa aaaattattt
    10141 tagcttgtat agcactagga gcaacgatct ctttgactgc ttgtggaaaa aatcaggaag
    10201 atgcaagcgg taaggtagaa atagagtttt ttaatcaaaa aaaagaaatg actcaaacga
    10261 ttcaggagat tgctaaagat tttgaagcaa aaaaccctga tattcatgta aaagttgtgg
    10321 atgtaccgaa tgctggtgaa gtaattaaaa cacgtatgct tgcaggcgat gtaccagatg
    10381 tcattaatct ttatcctcaa agtatagaat tgaaagaatg ggcgaaagct ggttatttag
    10441 aggacttaac cgaagaaccg tatttagaga atatcaaaaa tggatatgca caacgttttg
    10501 ctattgagga tcgtgtatat agcataccat taaccgctaa tgtctatggt ttttactata
    10561 acaaaactgc ttttgaggaa atggggattc aagcaccaga aacttgggca gaatttgaaa
    10621 aaatagtagc tgagattaaa gatcaaaaca aagtaccgtt tgcgattgca ggagcagaag
    10681 gctggacttt aaatggttat caccaactag ctatagcgac tgctgctggt ggtgaagagg
    10741 aagcgaacaa tgtttggcgt ttctcagaag ttaatggaat taatgctgaa agcaaagaaa
    10801 tgcaaaaaga ttttaatcga ttagatttgt taagagaacc aaaagctttg caaaacaact
    10861 ggcaaggtgc cggttataac gatacagtag ttacttttac aaaaggtgat gcgttgatta
    10921 tgccgaatgg ttcatgggca atgccgatga ttcattcaca aaatccagat tttgaagtag
    10981 gaacttttcc ttttccagca gatgaagcag gtcaaagtct aacgattggc gcaggagacc
    11041 tagccttatc agtttctgca acttctcaac ataaagaaga agccaaacgt tttgtagaat
    11101 atatgacaac acctgaagcg atgcagaaat attatgatgt agatggtgca ccgtgtgctg
    11161 ttgagggcgt tatcgagaat actcaggatt caccattaag tggtttaact gaacttgctt
    11221 ttactgatcg tcatttagtt tggttagcca aagattggaa tagtgaaaat gatttttata
    11281 ccttaacaac aaattattta cacaatggca atcaaaaagc catgattaac gcattaaatg
    11341 ctttctttaa tccaatgaaa gctgacggaa ggtaggaaaa taaaatgaaa ataaaagaaa
    11401 ttttaaatcg ttactgggca atcatttttg tagcaattcc aattattttg cagatgattt
    11461 ttttctactt tccaatggtt caaggtgctt tttacagttt aactaattgg actggtctga
    11521 cttataattt tgattttgtg ggtttgaaca attataagat tcttttttct gatccgaagt
    11581 ttatcaaatc gattggcttc actttaattg tgacgctttg catgattgct ggacaaattg
    11641 gttttggtat tttgattgcg cgggcgttga acgcaaatat taaagggaaa acattcttta
    11701 gagcatggtt cttttttcca gcggtcttat cgggcgtggt tgtttcttta gtatttaaac
    11761 aaatttttaa ctatggttta ccaaaaattg gtagtatgtt aggcattgaa tttttacaaa
    11821 ccagtctttt aggaacaaca tggggagcga tttttgcagt aatttttgtt ttactttggc
    11881 aaggaattgc catgccagtc atcattttct tagcgggttt tcaaagtatt ccacaagaaa
    11941 ttattgaagc tgctagaatg gatggggcga atgataagca aattttttgg aatattgaaa
    12001 tcacctactt attaccaagt atttcaatgg tatttattat ggcattaaaa ggtggcttaa
    12061 cagcatttga tcaaattttt gctttaactg gtggtggacc aagcgatgcc acaacatctt
    12121 tggggttact tgtttataat tatgctttta aaaacaatca gtttggttat gcgaatgcta
    12181 ttgctttagt cttatttatc ttaattggga ttgtttcact ggcacaatta aaattatcga
    12241 aaaaatttga aatctaggag gtttcccaat gaaaacatca aaagaaaaaa atatttctaa
    12301 atacttgctt ttattattag ggggcttcat gattttagtt cccttagttt caacgctatt
    12361 cggttcattt aaaacaacac ccgatattat gaataatttc tttcgttttc ctaatccagc
    12421 gactttggaa aatttccgaa gattgttagc ggatggaatt ggtcattact tttggaattc
    12481 ggcaatcatc acaatcattg cagtagttgc tgtgacagca attattccta tggctgctta
    12541 ttcactagca agaaaaatga ctcgtgggaa agcatacgga ttgatgtatt tatttttaat
    12601 tttaggaatt tttgttcctt tccaagtaat tatgattccg attaccgtta tgatgagtaa
    12661 aattggttta gcaaatatgt ggggattaat cttactctat ctcacttatg ccgtaccaca
    12721 gacactattt ttatatgttg gttttattaa actaaatgtg cctatcagtc tggatgaggc
    12781 tgctgaaatt gatggggcta gtcactttac aacttatttc aaaattgttt tcccaatgtt
    12841 aaaaccaatg catgcgacga ctattattct taatgctcta tggttttgga atgatttcat
    12901 gctaccatta ttaattttaa atcgtgattc taatatgtgg acactaccat tgtttcaata
    12961 taattatacg ggacaatatt ttaacgacta tggtccaagt tttgcttcct atacagtagg
    13021 aattgtcacg attacactag tttatcttgc tttccaaaga agtattatag ctggaatgag
    13081 caatggagca gtgaaataac caataaatta ttctcattat aaaggagttc ataaacttat
    13141 gattatattt gacaatcaca cacaaacatt tcatttacaa aataaaaaaa ttagctatct
    13201 attaggaatc gaagaaaata attatttaac gcatctttat tttggaaaaa agattacgca
    13261 ctattctggt gggtatcgct acccccgaac agatcgttcc ttctcaccca acaatgcaaa
    13321 tgcgcaagat cgtttattat ctttagacac attaccatta gaatttccag gatatggaca
    13381 tggtgatttt agagaaccgg cgcataatat taaattagga aacggtagtc gtgtaaatga
    13441 ttttcgttat gatagctacg aaattcaaaa aggaaagccc agcttagcgg gattgccagc
    13501 cttatatacg gaagatgatg atgaagctga aacgctgatt attcaattga aagacgcgat
    13561 tagtggattg actttacagt tgttctacac aatttatcaa aatcacagtg taattattcg
    13621 ttctacgcaa ttagtaaata atagtgatga aacagtggag attaaccgct tagctagtca
    13681 atcaattgat tttccaaatc gtccactcga gttaattcat ttaaatggta cctgggcaag
    13741 agaacgtcaa atgactagag aaaaaattca tacagggata aaagtattag atagtaaacg
    13801 cggatcaagc agccatcaac aaaatccgtt tgttgcttta gtagatgcca aaacagatga
    13861 atttcaagga gaggcatatg gatttaattt agtttatagc ggtaatcacg aaacggtgat
    13921 tcaaaaagat ccatttgacc aaacacgggt cattatggga attaattcat ttaattttgg
    13981 ttggcaacta aaaactggcg actcatttca aacgccagaa gtcgtgatgg tttatagtaa
    14041 tgaaggtctg aatacgttat cacagacgta tcatgaattg tataatcacc gtttaattcg
    14101 tggaaactat cgtttaaaag aacgtcccac gttaatcaac aactgggaag caacgtattt
    14161 tgattttaac gaagaaaaaa tcatgaatat tgtcgatgat gcgaagaact tgggcattga
    14221 aatgtttgtt ttagatgatg gttggtttgg cggtcgtgaa aatgacttca cttcattagg
    14281 tgattgggtt gaaacagaag gcaaacttgc ttgtggtttg gaaaatttag ccaagcaagt
    14341 gcatgataac gggatgaaat ttgggatttg gtttgaaccg gaaatgattt ctgaagatag
    14401 tgaactattt cgagcacatc cagattgggc attgggtatt ccaggtcgtg accgctcaat
    14461 tagtcgaaat caatatgttc ttgatttttc aagacaagat gttcgtgata atatctatca
    14521 acaaatgacg gcgatttttg atcgtgtacc gattgattat gtgaagtggg atatgaatcg
    14581 aaatatgaca gaagtctatt ctgtcttgtt ggactcaacg atgcaaggtg aagtggctca
    14641 tcgttatatg ttagggttat atgaattttt agaaaagtta acaacgaatt atccaactat
    14701 tttatttgaa agttgttcgg gtggaggcgg tcgttttgat gcaggtttct tgtattacat
    14761 gccacaaact tggacgagcg acaataccga tgccgtggct cgtctgaaaa ttcaatatgg
    14821 aaccagctta gtgtatccaa tttcaagtat gggtgcgcat gtttcagcag tcccaaatca
    14881 tcaaacagga agagaaacga gtttaactat tcgtggcaat gctgcgatgg ctggtgtttt
    14941 tggttatgag ctagatctaa cgcaattaac ttctgaagaa aaagcagaaa ttaaagaaca
    15001 agttgccttt tataaaaagc atcgccaact tttgcaatat ggaacttttt atcgcttgga
    15061 aagtccgttt gaaggcaatg atactgcatg gatgtttgtc tcaaaagacc aaacagaagc
    15121 catggtcttt tatttccgag tattagcaga agctgcgcat ccattagtca cattgaaatt
    15181 agcaggatta gcagaagaag caacttatca aatggaagat gtaacatttg ctggcgatga
    15241 attgatgaat ctcggttttt atattgactc agaactacat ggtgattatg cgacacaacg
    15301 cttttatttg aaacagatat agtagcttga atttacaata taagtgcaac accaaaagag
    15361 actcattcca aacgaagaaa atatgtttta tttacacgca tttactaaaa agcagcctga
    15421 tttgaattgg gaaaatgaag aagtacgtga agaaatctat gcaatgatta actattggtt
    15481 agataaagga ctaggcggat ttagaatcga tgcgatatta aacatcaaaa aaaaactaga
    15541 gtatggcatc tttgaatctg atggagaaga tgggttagcc ttcattgggc cctggattct
    15601 taatcagtcg ggcattgaag tgtggttaaa agaaatgaga gagcggacat ttaaaccaca
    15661 taatagtatg acggtagcag aagccgatgt tcctaatgaa cgtttagatg aatatattgg
    15721 tgaagatggc tattattcga tggtttttga ttttagttat acggatattg atgtacctga
    15781 aactggtgaa tggtttaaag atagccaatg gacatggacg gatatgcgta ccaatatttt
    15841 tacgaatcaa ttagttacgc aagataaagg ttggggcgcc ttatatttag aaaaccacga
    15901 tcaaccacgt tcaattaata aatatattcc agaagaatgg atcaatgatt atagtaaaaa
    15961 aatgttggcg acgcttttta tgttactaag aggtacccct tttatttatc aaggacaaga
    16021 actaggaatg accaacatag aaatggcatc attagaagat tttgatgatg tagctacgca
    16081 ttctcagtat aaacgggcat tagaatatgg attggcacca gagcaagcat tgaaagctgt
    16141 caataaacga agtcgggata attctcgcac acctatgcaa tggaatacgc aaaaaaatgc
    16201 cagattctca acttctgata atgtatggtt aaaagtaaat cctaattatc cagaactcaa
    16261 tgcagaagct cagttaacca atcaacagtc ggtattcaat tattatcatc aattaattaa
    16321 attaagaaaa aatagtgtat acaaagacgt gctaatctac ggacaatttc taccagtgaa
    16381 agataaaaat gaacatattt tgctttatga acgccaatta gaagataaaa tcgtattagt
    16441 tatcttaaac gttacagcaa cagaacaaga atattatgta gatgaacagt accaacaagt
    16501 attaatcaat aattatgaag atgttttatt agatcaaagt cgaaaattgc gtttacgacc
    16561 gtttgaaagt attgtattag ctaattatgg aggacaatta tgaaaattaa aaacgaagca
    16621 atgctcatca cctatgcaga tagtttagga aaaaacatgg gcgaattaaa acaagtctta
    16681 gacaaacatt tacaaggtgt tattggtggt gtacatctgt tgcctttttt tccatcgaca
    16741 ggtgatcgag gctttgcgcc gagtgattat acgacagttg atccagctct tggaacatgg
    16801 gaagatgtgg aagcattagg tgaagattat tatttgatgt ttgattttat gattaatcac
    16861 atttctcgtg aatcaaaatt tttccaagat ttcaaaaaaa accatgagca gtcaccatac
    16921 aaagaaatgt ttatccgtat tcatgaattt ttcccagaaa atcgaccaac acaagaagat
    16981 attgatttaa tctacaagcg taaagacaaa gcgccgtttc aaacggtaga atttgcggat
    17041 ggtacgacag aagaggtttg gaataccttt ggggaagaac aaattgattt agatgtgacc
    17101 aaagaagttg tgaaagaatt tattcgagaa accatcaaag atatggcgaa ccatggctgt
    17161 tctttaattc gattagatgc gtttgcttat gcgattaaaa aattagatac caatgatttc
    17221 ttcgtggaac cagatatttg ggaactttta gacgaagtgc gtcaagaagc agcgaaatat
    17281 gacgtcgaat tattaccaga aatccatgag cattattcca ttcaaatgaa aattgccaat
    17341 catgattatt atatctatga cttcgccttg ccaatggtca ctctgtattc actttatagt
    17401 ggaaaatcag aacgtttagc caattggttg aaaatgagtc cgatgaagca gtttacaaca
    17461 ttggatacgc atgatggaat tggtgttgtg gacgctcgtg atttattaac agatgaagaa
    17521 ttggattaca cctctgagga attgtataaa gtcggggcga atgtgaagaa ggtctattca
    17581 agtgccaatt acaataattt agatatttat caaattaaca gcacctatta tagtgcatta
    17641 ggcgataatg accgtagcta tctgttagca cgtgcgattc aagtatttgc gccagggatt
    17701 ccacaaattt attacgttgg gttattagca ggaaaaaatg atattgaact gttggaagca
    17761 acgaaagaag ggcgtaatat taatcgtcat tactatgatt tagccgaaat tgaagaagaa
    17821 gtgcaacggc cagtgattca acaattattt gcacttttaa aatttagaaa tgaatctgcg
    17881 gcgtttgatt tggatggaac gattgaagta gcaacgccat cagaatcaga aatagtgatt
    17941 acacgtaaaa ataaaaacgg tagtgatagt gcaacattaa cggctaactt ggatacgaaa
    18001 gaatttatca ttgagtctaa agatataaaa attttcacta gtgttgcatt aaaattttaa
    18061 cctattccat agaacaaaaa atcctttata ctagcacttg gatgacttat ccaagaccaa
    18121 taaaaaggac tcatacatgg ataagtataa aacaaataca gcatttaata aatggttttc
    18181 tgccataaaa ttaggaaaac tttctgtcaa ctcccaaaaa tgtatttttg attacaattc
    18241 gtatcgtaaa aaactgtctt ttgaagctgt gctcaagctc tttctctacg cagttaatga
    18301 agaaaaagaa agtttgcgtg atttgagtac agctcttatc gaccgatcgc tccaactaga
    18361 aaccgatgtg tcatcgatta gtcataccca attgtctcga gcatttaatg cacttgaacc
    18421 taaagtgtta gaagaaattt ttcaacaact gttagaaaaa gttcaacatc aaatcaaacc
    18481 aaccaagcga aatcatctgt atctgattga ttccagtacg ttttcgctta gtttaaaacg
    18541 tcataagtgg gcgactttcc gtcaaacaaa atcaggtgtc aagttacact taaactattg
    18601 ttatatggac gatactacga tgtatccaac tgattttacc ttaacaaatg cccatgaaca
    18661 tgatctcaat caactaccag tattggtgaa tcaaccagag gcaacttacg tgtttgatcg
    18721 tgggtattag gactttgaaa agatggatca gatgcattgg gatggctatt tcttcgtcac
    18781 tcggattaaa aaaaacacca aagttcacgt gatagatact ctggaaacat cgccagaaac
    18841 agaaattcta cgagacgagc tggttcgttt aggatctaaa acctatctaa ccgccaattt
    18901 ccgactagtc actgttcaag ataagaacgg acgtgtgttt caatttatca ccaatcgaat
    18961 ggacgtctct tcaaaagaaa tctctgatat gtatcacgct cgttggcaaa tcgaattgtt
    19021 tttcaagcac atcaaacaac acatgaccat taaaaccttc ttttctcaaa gtgaaaaagg
    19081 cgtgcagaat caattgattt taacgatgat ttccgctctc ctcacgtttc tcatcaaatt
    19141 ggagacgaaa acggaaaaat cagtgttcca aatcaaacga ttctttcgtt atttactgtt
    19201 tcagcccttt gaatgttgtc tagaaaaatt aattcccaca tgagaaaaaa gaaatttggc
    19261 tcgttacttt tggttttcag ttgaataaca gataaaaaat tttctggaaa aagtcatcct
    19321 ctgcgtcagc acagtttttt ttgacttatt ttcagaggaa atagttttca gaatattcta
    19381 aaatgtttta tgcaacacta gtgatatttt ttagaattag atttctaatg tgcatttttt
    19441 gagtattaag gagcaagtat acaaagattt ataaagctga ttaaatttga ataaaaatat
    19501 gcaggaacgc tactattttt agtagtgttc ttttttatat ttgaataaaa aatgtggtgg
    19561 ttaaatggtg gttataacaa aaaatgaatt aatgaaatta ggttatggga agtatcagtc
    19621 tgagagaatc atacgacagg caaaagcaat tatggtttca aaaagctata cctattacga
    19681 aaatagaaga ttaggactag tacctgttga atctgtagaa gaagttttag gtatgaagat
    19741 agaggtagag gaggattttc agaatcatgg ttaattttaa aaaagataaa aatgggaaat
    19801 atcattttac tgctagtttg ggattcgaca aacgaacagg gaaaagagta caaaaaaacg
    19861 tagaggggtt aaaacagtta aagaagaaaa aaagcgtata ccgaacttgt ttctaattat
    19921 ggaaaagaag cagaaacttc tcaaagtact atgttgtttg aggagttttt ttataaatta
    19981 ttcctacctt attatcaagg gaaagtagaa gaaagaacat ataaaaatcg gttatctaca
    20041 atcaaaaaaa cttttcttat ttctttaaaa tggagttaag agaaatacgt ccaattgaca
    20101 ttcaaaagtg gcaaaataat ttattgagca aatataaaaa ttcttatgta agaaacatgt
    20161 atgggatttt tcagatgtca ttagatcgag cagttgtttt gggactactt gaaaaaaatc
    20221 ctgcaaaagt tattggaaat gtgaagaaaa ggaaaactac agttgatttt tggacaaaag
    20281 aagaatttac aaaagttatt tcaacttttt atattgatga tttgtaccaa cattttggtt
    20341 ttatttgtat gtggttactt tttatgaccg ttatgcgttt gggagaagcc actgcattaa
    20401 cttggaaaga tattgatttt gaaaataaaa acttgcgtgt gaataaaaca ctctattata
    20461 agagagccaa aacctatgag tttgtagaac ccgaaacggc ttctagtatt cgtacaatcg
    20521 aactagacga caatacaatt acctttttaa aagcttggaa ggagcgtcaa gtttcaatag
    20581 gaggcatgtc gtttgtactt tcttataatg gaacacctac tcagaaatat acaatccgtc
    20641 atattatgag aagacatgca acgatcgttg gtgttcatat aatccgcata cacggattaa
    20701 ggcatagtca tgcttctttg cttatatcac aataaaaaga tgcacttcga attaaagaaa
    20761 ggttaaaaca tgctgatgta caaacgactt taggaactta tggtcatttg tatctaaatt
    20821 cattgagaga gataacaaat gatcccacag attatatcca aactaatttt tctaaaatca
    20881 aaccgacacc tatttacgat aataaaaaat aaatgataaa caaaagtagg atcacaccaa
    20941 aagaaacaca ctagaaaaac tataatacag gcttttctag cgtgttgttt cttatttccg
    21001 cctatttata cattatactc ataaagcatt taatgcatcg atcgtagccg cattgtctat
    21061 atgggtatat aaagttgttg tattggtact tgaatgtccc aattgttggg cagttaatac
    21121 caatgaattt gtctgttggt agagtctagt agctaatgta tgacgcagtt tgtgagggct
    21181 gacttgaatt ctaaagcctt ttgaatattt tgctaccatc cgttcgattg caataccgga
    21241 tatacgcttg gcttctcctt ggtaaattgc tagaaataaa gctttttcgt tttctgttac
    21301 tttatatcgt tctttccgaa tagctagata attagctaaa tattccattg cgaatgctgc
    21361 tatattgaca gcatctcttt tatttccttt tctagttact accacattat tcttatctaa
    21421 agataggtca tctaaattaa tatttataac ctcggagagt ctcaatccag atcctaaaat
    21481 cagtgcattg atcgccaggt ctctttctac atctcgttga taatagatca aagctcgttt
    21541 actcaaagta tttttatatt cattggcaat ataatctaga taattttgtg tatccttatc
    21601 tagaaataat tttttctcaa tggcattggc acgtgcagct aacgtagttt tatctgtgat
    21661 ggttgctact tgatccatag gattattgtc taagtatggt tttcctagag gattattgga
    21721 acttttcgaa agatatttaa atagaacctt taatgccgtg atatttctat tgatagtaga
    21781 agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct ctttttttac
    21841 attttctttt gtgcgacgtt tcaaatgaga tttgtacaag tttaggtcat aggcagttaa
    21901 ctgtcttatc gaggtgatag aagtatcagg aacgatagac tcactcagaa gccattcata
    21961 aaagagctta taatttttta gatattctaa agtggttcga ggtgattgat ctttatcctc
    22021 acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg tatctatttt
    22081 ttgatatatt tctgtatttt tcatgtcatt catcctttca ataagtaggg gagaagagta
    22141 tctctataat tggactatac caattataga atgttttgtc aattggtatg ctctaaaatt
    22201 tattaatttg tttcaaaaaa agcatataaa caggtatacg tttaataatt taaaataaat
    22261 ggtatacata aatagggaag gaaatagaag ggagcaatct aaattttttg aattttctta
    22321 attaattata tagaaagaac aatctttcta tagagttaga catgagaggg actatgcttg
    22381 atttaaaatc aacaagcgta tatactgtat atacaaagaa aaaggaggga gaagactatg
    22441 gcaattaaag aaagaaaatt tagggaagtg gggaactcag tagtattaac tatttcaaag
    22501 gagtttctta aagaaaatgg gttaaatccc ggagatacgg tttttttaga tgaagaaaaa
    22561 cttcgagcgg caattacaaa aaaacaagcc ttatctgatg aaattgattt agcaatatct
    22621 caagcattaa ctgaatatga tactactttt agagagcttg tcgataaatg agtattcatt
    22681 acctagaagc caaagatatt ataaaaatga atgtaatcca aataaaaaaa tactctccta
    22741 atgaacccct tggtgtaaag gatgcgaatg ctttagaaat gtgtgtaggg caacttcgag
    22801 cctcagcttt tggtgaagag gtttatcctt cgatttatga aaaagcagct atcctactta
    22861 tacaattgat aaagaaacat ccttttcaca atgcaaataa acgtactgct ttcttagcta
    22921 cttttgtctt tttgaaaatc aatggacagc ttttagctat tgatcaaaaa gatgctgtaa
    22981 atttagcggt atatattgct acgtatgata aggatttcga tcaactaaaa tatgaagtga
    23041 tcaacactat aaagacacat acgcagccca tttaaggagt tactgtatgt gtctttatag
    23101 ggttattagc tgctatagcg aaataattga agtaaattac aaatagctat aattcaaatc
    23161 caactatata gaaaacgtaa attttctata tagttggatt aagataacga ctatttattt
    23221 tatcatattt ttactatacc ctatactttt acttggtata tttatgaata atcgcaaatt
    23281 tacccctata ctactagttt gtaagttaga ttaataaaaa tactaaagtt atttgttctt
    23341 ttattaaata cacctacaac ttataaattg atggtattta gataacacga aagaataaaa
    23401 ataacagctg atagtaaagt ttgttgacga ttgctactca atcgaaagtg agttagtgcg
    23461 tatgaacttg cttctgaaaa cttatgaaat gaaagacctt ttacatcttg cagaaatcgg
    23521 tactgggatt aaactaagca ataaaaacta atgttcccct cattctttga acttctacta
    23581 tttgatttat ttattctgat aaatgacgat ttcaccttca ggatcttcaa atcccgtata
    23641 gaatttattt aagatctctt cagtatcagt aataggatag gcgataggcc acataccctt
    23701 tgatggttag aataaactgc tcaaaatctg tatcgtatgt tggctttagc atattaacaa
    23761 aggctatctc caaattataa accataagcg ttgaatcgtt cttaacaatt tcaattcttc
    23821 ctaacccaaa gtcagaagat ataattaccg gacttgcctt acccttcatg tgggttgttg
    23881 agattccata tttaaaggga attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa
    23941 taaaaaaatc tttcccctgc tagtctccta agtccctttg tagcggatat ggcaccataa
    24001 tctcatttta tcgaagtgag tcatggttta tctgttggcc aaccaaaatt gatacaatct
    24061 aacgatgcac cctctacggc attctagggg agtgcacttg cattcaccca ataaaaaccg
    24121 gcagttagca aagaacttat gtagtcgtat gttcttactg ttaacataca agaggtctcc
    24181 tttccacaat tgcttagcag taaacgggaa tttacaaagc taatctcttc cattttctta
    24241 tctttgttct aaaagtccca aatggagcaa ctgtatttac atgaataaat ttatatactt
    24301 cccatacagc cgttttggtt gcctcgtctg cccattttct tttgtgtgca gtgaatagat
    24361 cttcatcact cattgaatca atcatcatgt taatatcatc aatattacga ttgagaattt
    24421 cctctaattc tttcaatggt agatgtgcat aggtatttgt aaaccactta tataactctc
    24481 ctaactgatt ccatttaaat tgatcagaag gcgttttaac agataatcca tttctttcat
    24541 cattttccca ttttagaatt aaattcgtcc aaccaacttg atatgctaaa ttttcagcag
    24601 gtgttctatc cacttcctca actcttttat ccttcaattc ttcaggaata gtttcaaatt
    24661 ctaaaatata tttagtataa gtcctattta tttctttttt taattcttct ttatttttat
    24721 atgttctcat tatattacct ccataaattc ctaattgtct cctttaattc atctataatt
    24781 tcatccacga tattttaatc cgttctacaa tgcatatctg atatgcattg actgtctaac
    24841 tcatatgtga atgatttata aaatatccca acgtctcatc taaagaaatg ttgatcgtca
    24901 gcaaggagct aaaaaatacg aatatatttc ttttgtagta aaatcggact ggtttgcata
    24961 tcattttctt cgtaaatatc aaaatcatgt taactactat caattactaa taaaaactac
    25021 cactttaagc gttaagaact gttaagttta gttaagtgag gatagttcac aaaatccatt
    25081 gttaaacttc acgaaagtgg taaaactcaa aatgctttat ataggattac agcatcgctc
    25141 tttcttcgat tgcgcgttgg gtaaaaaata ttatgaagta aaaattgacg atgacacgtt
    25201 ccttacggct catcagatga aacagctaca aaaacgaaat gatcaactcg aagaaaattt
    25261 aattctaaaa aagcgattgc catattcacg cctcgctcga cgaactatta aaggtcaaga
    25321 tttacctgaa gatcatcctt tttaggaaat tgaagctttt tatgttgcac aatgcattta
    25381 taatactaca atgatgtttt caccagatat tcttctaggg tgcggtgtaa tgaaacagat
    25441 acacttgcaa aagaaaattc accgcgaatt tactaaaatt atgaataatt atgttaatct
    25501 tccgaaattt ttttccaaaa ttaagggatc aagctggtgt tatagattgt ttaaggttgg
    25561 caaaaaaata acttcttttt aaacaattat agaaaaccga tactctgtta agttggttga
    25621 cacggtgtcg atttttatga ctttcttatt ctgaaacttc actaacggac agtacctaaa
    25681 aagtctatag tatggacgtt tacgagtact attttatcaa aaatgctgct catttcaact
    25741 tatatgtttt agtgaactac ccccacttag c
//
LOCUS       DACGLI010000044        25391 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.045, whole genome shotgun sequence.
ACCESSION   DACGLI010000044 DACGLI010000000
VERSION     DACGLI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.045"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(35..400)
                     /locus_tag="IXT22_001980"
     CDS             complement(35..400)
                     /locus_tag="IXT22_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863319.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            608..1090
                     /locus_tag="IXT22_001981"
     CDS             608..1090
                     /locus_tag="IXT22_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863320.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1287..2177
                     /gene="pstS"
                     /locus_tag="IXT22_001982"
     CDS             1287..2177
                     /gene="pstS"
                     /locus_tag="IXT22_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAQ4863321.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2503..4976
                     /locus_tag="IXT22_001983"
                     /pseudo
     CDS             2503..4976
                     /locus_tag="IXT22_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
     gene            complement(5079..6815)
                     /locus_tag="IXT22_001984"
     CDS             complement(5079..6815)
                     /locus_tag="IXT22_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAQ4863322.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6812..7516)
                     /locus_tag="IXT22_001985"
     CDS             complement(6812..7516)
                     /locus_tag="IXT22_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4863323.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7647..8150
                     /locus_tag="IXT22_001986"
     CDS             7647..8150
                     /locus_tag="IXT22_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAQ4863324.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8110..8448
                     /locus_tag="IXT22_001987"
     CDS             8110..8448
                     /locus_tag="IXT22_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAQ4863325.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8469..9887
                     /gene="ffh"
                     /locus_tag="IXT22_001988"
     CDS             8469..9887
                     /gene="ffh"
                     /locus_tag="IXT22_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAQ4863326.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9999..10577
                     /locus_tag="IXT22_001989"
     CDS             9999..10577
                     /locus_tag="IXT22_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAQ4863327.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10581..11102
                     /locus_tag="IXT22_001990"
     CDS             10581..11102
                     /locus_tag="IXT22_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4863328.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11181..11735)
                     /locus_tag="IXT22_001991"
     CDS             complement(11181..11735)
                     /locus_tag="IXT22_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4863329.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11988..12263
                     /gene="rpsP"
                     /locus_tag="IXT22_001992"
     CDS             11988..12263
                     /gene="rpsP"
                     /locus_tag="IXT22_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAQ4863330.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12275..12526
                     /locus_tag="IXT22_001993"
     CDS             12275..12526
                     /locus_tag="IXT22_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4863331.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12650..13441
                     /locus_tag="IXT22_001994"
     CDS             12650..13441
                     /locus_tag="IXT22_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863332.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13611..14132
                     /gene="rimM"
                     /locus_tag="IXT22_001995"
     CDS             13611..14132
                     /gene="rimM"
                     /locus_tag="IXT22_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAQ4863333.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14122..14883
                     /gene="trmD"
                     /locus_tag="IXT22_001996"
     CDS             14122..14883
                     /gene="trmD"
                     /locus_tag="IXT22_001996"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAQ4863334.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15019..15366
                     /gene="rplS"
                     /locus_tag="IXT22_001997"
     CDS             15019..15366
                     /gene="rplS"
                     /locus_tag="IXT22_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAQ4863335.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15676..15918
                     /locus_tag="IXT22_001998"
     CDS             15676..15918
                     /locus_tag="IXT22_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAQ4863336.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            16269..16523
                     /locus_tag="IXT22_001999"
     CDS             16269..16523
                     /locus_tag="IXT22_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4863337.1"
                     /translation="MLELSKQLPVSDPRHFDYEEIAIKILEELQKNYTTKRVNGSNGL
                     LLHAVYDKNSLKGVDECVIWGDYFYVEGITRLAKTWYCYW"
     gene            16552..17811
                     /locus_tag="IXT22_002000"
     CDS             16552..17811
                     /locus_tag="IXT22_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863338.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            17864..18760
                     /locus_tag="IXT22_002001"
     CDS             17864..18760
                     /locus_tag="IXT22_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863339.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            18771..19640
                     /locus_tag="IXT22_002002"
     CDS             18771..19640
                     /locus_tag="IXT22_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863340.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19650..20325
                     /locus_tag="IXT22_002003"
                     /pseudo
     CDS             19650..20325
                     /locus_tag="IXT22_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20531..22195
                     /gene="alsS"
                     /locus_tag="IXT22_002004"
     CDS             20531..22195
                     /gene="alsS"
                     /locus_tag="IXT22_002004"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAQ4863341.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22208..22918
                     /gene="budA"
                     /locus_tag="IXT22_002005"
     CDS             22208..22918
                     /gene="budA"
                     /locus_tag="IXT22_002005"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAQ4863342.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23048..23545
                     /locus_tag="IXT22_002006"
     CDS             23048..23545
                     /locus_tag="IXT22_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAQ4863343.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            23730..23990
                     /locus_tag="IXT22_002007"
     CDS             23730..23990
                     /locus_tag="IXT22_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863344.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(24352..24591)
                     /locus_tag="IXT22_002008"
     CDS             complement(24352..24591)
                     /locus_tag="IXT22_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863345.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            24877..25191
                     /locus_tag="IXT22_002009"
     CDS             24877..25191
                     /locus_tag="IXT22_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863346.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8415 a         4309 c         5220 g         7447 t
ORIGIN      
        1 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
       61 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
      121 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
      181 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
      241 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
      301 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
      361 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
      421 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
      481 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
      541 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
      601 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
      661 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
      721 cctgatccaa ggaagcggat tagtggtttc taggaatttt ccagctttga ctgttttcta
      781 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
      841 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
      901 gattatcggc cctaatggtt tgagcgagag tggattgaag gattcagctt attcctccat
      961 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     1021 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     1081 taactattga tggtggatca tcagtaaaaa agcatatgag ctgcgtaaaa tgcatgtttc
     1141 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     1201 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     1261 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     1321 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     1381 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     1441 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     1501 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     1561 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     1621 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     1681 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     1741 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     1801 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     1861 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     1921 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     1981 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     2041 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     2101 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     2161 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     2221 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     2281 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     2341 aaaagagcta cgacatagaa ctgtcgtagc tttttttttg ctatatgaca ggaatgaaag
     2401 gtgtttgcaa gcttaatgtg aggaacactt tccatatctg ttctatactg gataggagaa
     2461 gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc acatgaagaa taaatggata
     2521 aatcgaagta aaaaaaagaa agtaacacaa agatcatcag ataaagtcat ccgtcttttt
     2581 ccatcgtata aagaaggatt aacggcagat caagtcaagg aacgaataga aaaaggtgca
     2641 gcaaataatt cagtcgatcc cacattcaaa acaaatcagc aaatcgtatt ggaaaacata
     2701 tttacgtatt tcaatttgat ctttcttatc ttagccattt tgctttgttt agtagaatcc
     2761 tataagaact tgactttttt accagttatc atagccaata caggaatcgc catttttcag
     2821 gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt taaatacagc aaaagtcaat
     2881 gtcatacgag acgggataga acaaacaata gatatagaag accttgtaat agatgacatt
     2941 gttattttag agactggaca tcaaattcca gcagatgcag aggtcgtgga agggaaactg
     3001 caagttaatg aggctttatt gacaggcgaa gcagatgaaa taaccaaaga aataggcgat
     3061 ccattaatgt ccggcagttt cattgtttcc ggaaaagctt acgcccgatt agacaaagtt
     3121 ggagcagatt cgtatatttc ccagctgaca gtcaaagcca agacaatggg agaaggagaa
     3181 cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat ggattgggat catcattatt
     3241 cctatcggta tcctgctttt ttctcaaagt tactttttta atggaaacac gatcaaagaa
     3301 agtgtcgttg caatggaagc agcattgatc ggtatgatac ctgaaggact gtacttgctg
     3361 acgacgattg cattagcatt aagtgcgact aaactagcaa agcaaagagt tcttttacac
     3421 aatatgaaaa gcattgagac attggcaagg gtaaatgtcc tttgtgtaga taaaacagga
     3481 acgatcacag aaaataaaat gtctgttcaa aaagtgatcg tctctaaaaa acaagaaata
     3541 atcagtcagt cagatcaatt ggaagcatgc attgctgact atgcaaaagc gatggcagga
     3601 gacaatgcaa caatggaagc tgttaaagca tattttacaa aaaccactga tcaatcctat
     3661 caccatgtta ttcctttttc ttctgtccaa aaattcagca gtgtagcgtt ggcagacaag
     3721 gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc aattgccgga atatgcggaa
     3781 gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg tctttggtgt gtacgatggg
     3841 attcttgaag aaccagtatt gacagaagca gtcacaccat taggctatat tctgattgct
     3901 aatcctatca gaaaagaagc aagagccaca tttgattact tcaaaaaaca gcaagtagcc
     3961 atcaaagtga tttctggaga taatccgctc accgtatcca atgtagctgt ccaagcaggg
     4021 atttcacatg ctgatcagta cgttgatgca tctaaattat cagaagaaga atatgaagca
     4081 gctgtcgaaa aatatacagt ttttggacgc gtcaagccag aacaaaagaa aatcttcgtt
     4141 caattgctaa agcgtcgtaa caatacagta gctatgacag gtgatggcgt gaatgatatt
     4201 ctagccatga aagaagcaga ctgcagtata gcgatggctt ccggaaatga agccgccatg
     4261 caggcctcac aagtggtctt acttgattct gacttttcac gcatgccaga agttgttgca
     4321 gaaggacggc gcgttgtgaa caatattgag cgatcagcca gcttgttttt agtgaagaat
     4381 attttctcct ttttgctctc actgttttca gtgatctttg ctctgaccta tcctttagaa
     4441 ccatcacaaa tcacattgat tagtttgttt actatcggac ttccatcttt cttgcttgct
     4501 ctagaagaaa acaaaaagcg aatcagaggg aaattcatca tgaatgtgat ggaaaaagct
     4561 gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt tggtgatctg cggggtgact
     4621 ttgaatctaa ataaaacaga tgtttctaca gcatctacca tgcttttgat tgcagtaggg
     4681 ttcctcgttc tctataaaat ctgttcaccg ctgaataaat tcagaagtca gatcattctt
     4741 ttctgtgcta gcggtaactt tttttcggtc atcttttgca taagctgttt tcaatcaccg
     4801 gtatctcagc tgtatcactt ttgctgttga gcattctatt tttctcggca gattcgattt
     4861 ttaggcattt gaccacattg gtagaatatt tgtttgaacg taaaaatgaa aaagagcaaa
     4921 agccgtttag tcgcgtagtt aaaaaatttc tatcgatatt taaacgagaa aattgacgaa
     4981 aagtatctca aaaaagagta aaaaagaaca accactcgtg tatctttcga agcaggatga
     5041 gtcatccaac tttaaaacgc acgagcagtt gctctttttt acattttcgg aatggtaacg
     5101 gtgaaagtcg aacctgttcc aagatgactg tctacagtaa tcgtaccatg aaggagttgc
     5161 acgtagtctt ttacaatcgc taaccctaat ccggtcccgc ctgaatgccg gcttcgcgcc
     5221 ttgtctacgc ggtaaaaacg ctcaaagatc cgttcctgat cctcaatgtc gatacctata
     5281 ccaaagtctt ggacagaaaa cgatagatca tctgttgcct gatagcggat aataatctcg
     5341 ctgtcgcttt ttgaatattg gacagcattt tcaatcagat ttttgataat tggataaagg
     5401 atatctgttt tagtagtaaa tggttcgttc tttccaatca atcgaatcgt caaccgtttc
     5461 ttttcgatga ttggctgata attttgaacg atttgctgga aataaggttc tgtataaatt
     5521 gtctggatct cgtaagaatt ctcgccatct tttgacagct ggatgatttc ccgaatcagt
     5581 ttatctaacc ggatcgcatc tttttgcatg atctcaagaa aagaagtcag agtttgcggg
     5641 tcatcttttg caccatccag taaagtctcg gtaaaaccaa tcagtgaagt cacaggagtt
     5701 tttaattcgt gagagacgtt gccaacgaaa tccttttgta gcttttctaa acgtcgcact
     5761 ttcgttaagt catacgccac ccctagaatc tgtccggtac cttctgaatt agtaaagtag
     5821 cgcaaactca agtctaatgt ctgccgacct tctgtaaggg tgatctcctg atggatcagc
     5881 ggatgctcag gagtcacttg atgaatcagc tgaatgagtt ttggctcttg aatgacttct
     5941 gtgtaccgct gttcaggttg atagcttacc acgtttaaat gtagctgcat ctttggatta
     6001 agcagtagta aacgagaatc agcatcatca atcaggaata cgccaatcat cagttcgttc
     6061 agtaacgtat ataattgctc ttctgtggta gtatacgccc gatacatctt actcatttgt
     6121 tcgctcaacg cattgatcgt ctgatacaat tcttcccatt gatcgggtgt ttgcatgatt
     6181 acttccgcct gattaggatt ttgcaccatt ttttttagta cgggcagcac ggttttcaat
     6241 ggctggtttt tttgatagat cagataatag atcattcctg caagaacaag gaagaaagac
     6301 agaaagaaga aaaagaccca acggcgaaaa ctctcagttc tcggtaaaaa accgcttgtc
     6361 ggttctgcga tacgtaaaat ggcttctaac tggccacttt ttttgactgg taatgcgaca
     6421 tataaaagat ccccattcaa agtagtactt ttgcgcaaag cgctacctag gttcccacca
     6481 ttcaatacgg ctttgatttc gggacgggag tttcgctgtt cattcaatgt ttcattgttt
     6541 gtgtcaaata agatctttcc agtagcatcc attaaagtaa tccgttcgtt cgactgatgg
     6601 acgaattctt ccaaagcagt tttgttttgc gctgcttgga ggttttcgac atctaattgc
     6661 cggatcagca gttgtgcttt ttttgtcagg tagctttctt gctgttccac gatctgctgt
     6721 tgaaaataat gggaaatcaa ttgccagcca ccaaaaaaca aactaactaa aagaataaga
     6781 aagaagagac gttcataaat ttttttccat ttcatcgttt gggttcctga aacttatagc
     6841 caaatcctct aatagtcacc aagtactttg ggtgttttgg atctcgctcg attttttctc
     6901 gcaaatgact aacgtgtaca tctacgattc ggctttgtcc tgcgaagtca aaattccaaa
     6961 tgcggtctag caatgtgtct cggtcgatca cacggtcttt tcgtttcatg aaataaacaa
     7021 gtaattcaaa ttctttcggt gttagttcaa tcagatggtc gtctacggtc acttgataat
     7081 tggtcaaatc agcagtgatt tgtccaatcg atagatattc aggctcagct tcatcttttg
     7141 attgcttacg aggttcaatt cgtctgaata ttgctttcat acgggctaat acttcgcgag
     7201 gactaaatgg tttggtcaaa tagtcgtcag cacctatttc taggccaatg atccgatcca
     7261 cttggtcatc tttagccgtc agcatcaaaa tcggtgtttc atttttttct tgacgcagcc
     7321 gctgagtgat ctccatgcca tccatcgttg gaagcatcac atctaaaatg atgaaatcaa
     7381 atgattgttc taatgctaat tctaatcctt cgcctccatc tgtggcactg gttaccttgt
     7441 agccttcttt ttccaaattg aacgtcaaga gcgttacaat agaaggttca tcatcaacaa
     7501 ctagtatttt tttcattcaa atctccttta aataggtttc attctgttta tattttagca
     7561 tagaatcagt acaaagggct attttacaaa agaaataaat ggtataatag gaaggcactt
     7621 tgctgaatag aaaggaagag cagtcaatga ttggaatcag tgcatgttta ggcggtctgg
     7681 cctgtcgcta tgatggacag aaaaaagaag taccagaatt gatggaacta gttgaaactg
     7741 gagaagctgt catggtctgt ccagaagtga tcggcggatt accaattcct agagatcccg
     7801 ctgaaatcat tggtggaaat ggattcgatg tgtggaaaga tcaagcaaaa gtatggacga
     7861 caagcggcga agatgtaacg gaagcgtaca aaaatggcgc gatcaaagcc tatcaaaaat
     7921 tgcaggaaaa acacattgat ctagtcatca tgaaggaaaa aagcccttca tgcggaaccc
     7981 attcgattta tgacgggagt ttttccggaa taaaaaaaaa tggtgccgga gtggctactg
     8041 cttattttat tcagcaaaaa atgactgtgc tctctgatga agaatggctg aaaactagag
     8101 gtgagcagaa tggaaatcga aaagaccaat cgaatgaacg cgctctttga attttattcg
     8161 accttattga cagaaaaaca aatgaactac atggaattat attatgcaga tgatttttca
     8221 ttaggtgaga tcgcggaaga atacgaagta agccgacaag cagtatatga caatatcaag
     8281 cggacaagca agatcttgga ggattatgaa aaaaaacttc atcttttttc taattatatt
     8341 gttcgagaac aggtattgga aaatatgact gcatatatta cagataagta cccggaagat
     8401 aaaaaactac ttgaatatgt acagcaaatt caagcaatcg aagaataaat aaaaggaatg
     8461 aagaaaatat ggcatttgaa agcttaactg aacgtctcca gcaggcgatg ggaaaaataa
     8521 gaaaaaaagg aaaagtatca gaagctgacg taaaagaaat gatgcgggaa atccgccttg
     8581 ccttactaga agccgatgtt aacttgcaag tagtcaaaga ttttactaag cgcgtacgcg
     8641 aacgtgcggt aggggcagaa gtgctggaaa gtttatcacc tgcacaacaa atcgtaaaaa
     8701 tcgttgatga agaattgacg atcacacttg gttctgaaac agcagagtta aataaatcac
     8761 caaaaatacc aactgttatc atgatggctg gtcttcaagg ggcaggtaaa acgaccttta
     8821 ctggtaaatt agccaattat ttaaagaaaa atgaaaatgc tcgtccgctc ctaatcgcag
     8881 gggacgtata tcgaccagct gcgatcgacc aattgaaagt attaggtcaa cagctagacg
     8941 ttcctgtatt tgatatggga actgaagtca gcccggtaga gatcgtccgt caagggatgg
     9001 agttagcaaa agaaaagaaa aacgactatg tattgatcga tacggcagga cgtctgcata
     9061 tcgatgaaac attgatggat gagttgaaac aaatcaaaga attgacgcaa ccaaatgaga
     9121 ttttgcttgt tgtcgatgcc atgactggtc aagatgccgt caacgtagct gatagcttca
     9181 accagcaatt aggtattaca ggggtcgtca tcactaaact tgatggggat actcgaggcg
     9241 gggcagcact atcgatccgc tcagtgacag gcgcaccaat caaattcatc ggttctggtg
     9301 aaaaattgac tgacttagaa gtattccacc cagatcgtat ggctagccgt atccttggta
     9361 tgggggatat gctgacattg attgaaaaag cgcagcaaga ctatgacgag aaaaaagcgg
     9421 aagaacttgc acagaaaatg cgggaaaatt cattcgattt caatgacttt attgaacagc
     9481 ttgatcaagt gatgggtatg ggcccactgg aagatctaat caaaatgatc ccaggaatga
     9541 atcaagtccc tggaatcgaa aacgtcaagg tagatccaaa agatgttgaa cgcaaaaaag
     9601 cgatggttta ttctatgacg ccagcagaaa gagcaaatcc tgatctgttg aacccaagcc
     9661 gtcgtcgccg aattgctgcc ggttctggaa acagtgttgt tgaagtgaat cgaatgatca
     9721 aacaattcaa ggaatcaaga aaaatgatgc agcaaatgtc caaaggggat atgaacatcc
     9781 caggtatgga ccaaatgttt ggttcaggcg tcaaaggaaa actaggcaaa atggcgatga
     9841 atcgaatgat caagaaaaat aagaagaaaa agaaaaaacg gaaataagat gaaaaaaaca
     9901 gcttcggtac agactgaaaa tgtctactgc cggagctttt ctatcagcaa tttttattct
     9961 ttactaatac aattactcta aacgaagagg tggcacagat gagatgtccg tggagtgaac
    10021 aaacagaaag tatgcggcaa tatcatgata ctgtctgggg tgttcctgaa tatgatgacc
    10081 aaaagctgtt ccgaaaattg atgcttgata ttaatcaagc cggattgagc tggcagacga
    10141 ttttaaataa aagtgaagca ttcgatgaag catatgatcg attcgatatt aaaaaagtcg
    10201 caaattatgg agaaacaaaa atcagtgaac taatggaaaa caaaggaatt attcgtaacc
    10261 gaagaaaaat cgaagcagcc gtccaaaacg ccaaagcagt cttgaaaatt caagaagaaa
    10321 tcggcagttt ttcagagtat ctttggtcgt tttctaatgg aaaaatcgtt gattcttctt
    10381 atcattcaca agaagaagtc ccaacaacaa gtcctctttc agatgaatta gcaaaagatc
    10441 taaagaaaag aggatttaaa tttatcggaa gcacaacaat ctatgctttt ttagaagctg
    10501 tcgggatcat caatgatcac cttgacagtt gtttccgcaa agaagaggtc gtacgtatcg
    10561 gcagaaaggg cgaataaagc atgcgaaaaa tcatatttta tggtgctata agtttagatg
    10621 gctatttggc aacgaaaacg gatgatcttc aatggctttt tgacactcca acaggtaagc
    10681 aaaccactta tgaagctttt tatgaaacaa tcgatacgac catcatgggc agaaaaactt
    10741 atcaggaagc aaaaaaatat ttggagaccg aagcaattta tccagagaaa aagaatttcg
    10801 ttttttccac ccacgcacaa ttacaattgc cagatgctga ggtcgtaaac gaagatcctg
    10861 ttgcttttct aaaaaatcta caaatgacag aaggaaaaga tatctgggtt gtgggtggcg
    10921 gtcgattgat caaaccgcta ttggaacatc aaatgattga tgaatggtat atccagatta
    10981 cccctgtatt attaggggac gggattcctt tattccaaaa aggaacatat gaagcgcgtt
    11041 ttgaaatgct agacacgaca cgattcggtg aatttatcga attgcattat gtacgaaagt
    11101 agaagtaaat aaaataaaaa aggcaactat atgcagaaat gtcctgtaca tagttgcctt
    11161 ttttattacc gttatgcttt ttactctgtt aatttgttag aaaaatctag atacgcatct
    11221 aaaatcgttt ggaagaaact taatgttcct tcaacgatat taccattttc atcaattaga
    11281 ttcgcaacgt ttccgatata tgcttccggt tgctgcaagg ttggcacatt caaaaagaca
    11341 agtgattgtc gtagatggtg gtttgcgcca aagccgccga tcccacctgg tgatgcagta
    11401 acgactaaac ctggtttatg atcccaaaca ctgtgtccat aaggtcttga gcctacatct
    11461 aaagcatttt tcaatactgc tggcacagaa cggttgtatt caggagtaac gaaaacgaca
    11521 ccgtctagtc ccctcacttc ctcacgaaaa cgagtccatt cagcaggagc ctgttctgga
    11581 gtttcgagat cctcattgta aaatggcaga tcatcgattt ttacaaatac actttcgtac
    11641 ccttcaggaa gcaatttcgc aaaagcttct gctacttttt tgttgtaaga atcttttctt
    11701 aaactaccaa taaaaaatcc aatttttttt gtcatacgat ttttcctcct tcaaactatc
    11761 tataacaatc ttacaaaaaa taagtaactg gagcaaataa aaacacttac tgacaaaagc
    11821 tacatagaag atagattact tatttttaac aaaaaagaag tctaaaatct tctatttcct
    11881 aaaaaaaatc gaatttaatc aagctgtaaa gaaaaaaagc tttacagggt aaaaaaaaac
    11941 tgttacacta catcttgtga ataaaacaat ggaggtggaa ataaataatg gcagttaaaa
    12001 tccgtttaaa acgtatgggt tctaaaaaga gtccgtttta ccgtatcgtc gtagctgatt
    12061 cacgttctcc tcgtgatgga cgtttcatcg aaactgtagg tacttacaat cctttgaaag
    12121 accctgcaga agtagtttta aaagaagact tagttcttga ctggttatca aaaggtgcac
    12181 aaccttctga cactgtacgt aacatccttt caaaagaagg cgttatgcaa aaacaccacg
    12241 aagctaaatt ctcaaagaaa taaggtgacc ggatatgaaa gatttaagcg acttagtctt
    12301 aacaatcgtt cgtccgctag tcacttatcc tgatcaagtc aagttagacg tcgtagagtc
    12361 gaaagacttt tacgagtaca atctaacagt ggctcctgaa gatattggcc gtatcattgg
    12421 aaaacaaggg cgtgttgcta aagcaatccg cacaatcgtt tacggtgttc ggatcaatgc
    12481 accgaaaaaa gtgcgtttga atatcatcga tgataaggaa aagtaaataa acgtgctgta
    12541 ctcgaatttt cgagtgcagc ttttttgttt ttttattaat tgaagaaatg attatttggc
    12601 aaaacaagca agaaagcgta tccttatagg aggagggagt gaacagccaa tgagaaagaa
    12661 aatgttattt attccatttg ctctattgtt aagcgcttgt agttcggtta ctcaagaatc
    12721 agacaataca catctatcaa gcagtatatc tgaaactgtt accagtccag aaaaaagtag
    12781 taccaaaacg gctaccacca ctgaacaaac aatggctacc tcaaataatg agaaaaagac
    12841 tgctttagac cagttgaaag aacaacagcc aaatgttccc atgcctctag atgtaccagt
    12901 ctcttcaggc tatctcaata tcgcagcgac acatacaaag caaggttatt ctattttata
    12961 ttacagaaca gatcgtcccc tcgggttgaa tgctgacgaa ttgaatcaag aaacgcctat
    13021 tgcaacctat ctatatcaat atgggtttgc ttctagtcaa gaaacaatcc aagttttgca
    13081 gccctttgag atcgacacaa atggtcagca agtggactta ggttctcgaa tcacagggta
    13141 tcagcaaggt gcagcaggtt caagttttct tgaatggcaa gaaggaaact ggcgtattcg
    13201 aatccgtggg aataatatag aaggccaaga tcccttacta ttagctaaag aaatcgtagc
    13261 ttatttggaa gaaaacagtc taccagcacc tgaacaattt ggtaaaatta ctgttgatat
    13321 gggtgatacg acgaatcgag ccgtagaagt aagctggcaa gaaccgaaaa atgcctatac
    13381 gatcactcat caagatccta tgtctgcgtt gaagatggca gtttctatga agaggttgtg
    13441 aaatcagcgc gctgatctga gcccatcatt taactccaag tcacaggaag taatcaaaaa
    13501 tagcacgccg catttttgca taattttggc ttaatacctt aaaagaaaac tagaattgcc
    13561 tcttcacaca tgctaaaata aaacagacaa aaaagaaatg gggatataag ttgactgaat
    13621 acttgaatgt aggaaaaatc gtaaacacac aaggtatcaa aggcgaagtc cgtgttatct
    13681 caacaacgga tttcccagaa gaacgttaca aaaaaggaac ggtgttaaca ctattccaag
    13741 acggaaaagc acctgtggaa ttaacagtca aaagtcatcg caaacataaa aattttgact
    13801 tattgagttt tgaaggacat ccttctatca atgatgtgga aaaatatcgg gatggcatat
    13861 taaaagtgtc aaaagacaac tctgtagatc tagctgaaaa tgaattctat taccatgaga
    13921 tcatcggtct gcatgtatta gaagatggaa ctgagttagg taaagtaaaa gaaatcttgt
    13981 caccaggtgc caatgatgtt tgggtcgttc aacgtccgaa aaaagctgat atattgcttc
    14041 catatatcgc ttctgtcgtc aaagaagtcg atttagaagc tggagtggtc cgtgtagaaa
    14101 ttccagaagg actgattgac gatgaagatt gatgtattga ctttatttcc aagaatgttt
    14161 gaaggtccta tgggggaatc catcatcggt aaggctgtag ataaaggatt attagatatc
    14221 aatatctcta acttccgcga ttattcagat aacaaacatc agacagtaga tgattatcca
    14281 tacggcggtg gagcaggtat gctgctcaaa gtccagccca tctatgataa catccaagcc
    14341 attgaaaaag ctgcaccgga tgtcaaaaaa agagtaattc ttcttgaccc agctggtaaa
    14401 cgattcgatc agaaaatggc agaagaattt tcacaagaag aacacttagt attcatttgt
    14461 ggtcattatg agggatatga tgaacgtatc cgcacattag tgacagatga agtttcctta
    14521 ggagattatg tccttactgg gggagaatta ggtgcgatgg tcatgatcga tgcaacagtt
    14581 cggcttttgc cagatgtgtt agggaatcag acttcagctc aaacggattc ttattcaacc
    14641 ggtttattgg aacatcccca atatactcgc ccggcagaat ataaagggat gaaagtacca
    14701 gaagtattga caaatggaaa tcataaattg attgaagaat ggcaattaaa agaatcacta
    14761 agaaggacct atcaacgtcg gcctgatctt ttggaaacac ttgaatggac acctcaaatg
    14821 acgaaatttt tagaagaaat caagaaagaa gaacaagaaa aaacagcaga tgaagccaag
    14881 tgactttttc taaaatattc tttacagtag gttgataata tgttagtatt ttatggtgag
    14941 tgcaaaagca cttaactatt acgatattcc gctatgagaa aagctcataa gaatatttgg
    15001 aataaggaga agaaaaccat gaatccatta atcgaagaat taacaaaaga acaattacgt
    15061 tctgacatcc cagcgttccg ccctggtgac actgtgcgtg ttcacgcaaa agttgttgaa
    15121 ggtactcgtg aacgtatcca gttatttgaa ggtgttgtta tcaaacgccg cggtgctgga
    15181 atcagcgaaa cttatacagt acgtaaagtt tctaacggag tgggcgttga acgtacattc
    15241 ccattgcata caccacgtgt tgcaaaaatc gaagtagttc gctacggtaa agtacgtcgt
    15301 gcaaaattgt actacctacg tgcattacac ggaaaagctg ctcgtatcaa agaaatccgt
    15361 cgttaatcat tgttatcaga ctgagaaaga acccttggta ttcaagggtt cttttttctt
    15421 agcatgtaat ttgaacaccc tgatccagtt tttttcttta attattggta ggggagaata
    15481 atggattaga ataaatctac ctataagtag tagtaaaaaa aagagcacta tgataatatc
    15541 tttcttaaga gtaaccgctt taataaaaaa tccagaatat tctaacataa atggagtatt
    15601 cttagaatca aaaggagaaa gaagatggtt tatacttata cggagcaaga aaaaatgaaa
    15661 gtttgagaca cattcatgaa tgatggaaaa gtaaaacaag taccaagttc aacaaaaaag
    15721 aaaaacatcc tattgaaaga agtcttgaaa cgctttgacc atggagtgac ttatacagaa
    15781 acagaggtta attcgatact gctgaacgta ttttctagtg gcgattatgt cgaacaaaga
    15841 cgttatctaa tcacatttgg ctttttcaaa agaagttcag acggtcgggc atatcagatg
    15901 atgggaattg aaaattagaa gttttaattt atactcattg aaaaaagttc aagtatgcga
    15961 tattggttct acaccgcata cttgaacttt ttttgtcatc tgtatctata atacaaagcc
    16021 aagaacgtta ttcaaaatat ggatagctat gataaaagct aatgagcgat tcgcagttaa
    16081 ataagcaatc gtcagtaaaa tcgttccagg agcgtacatg aaaaaatcaa ttggatgcgt
    16141 tacatgaata aagataattc tcttttattt gtacgaataa ataccaaaac gtacctccta
    16201 aaattagatt caaagaagat agcaaagagg aaaaagatag ttctgcagca gctatagcgg
    16261 catgtggatt gctagaactt tccaaacaac tgcctgtttc agatcctcgt catttcgatt
    16321 acgaagagat agcaatcaaa atcttggaag aattacagaa aaactataca acgaaacgag
    16381 ttaacggatc aaacggtctg cttctccatg ccgtttatga taaaaacagc ttaaaaggtg
    16441 tagatgaatg tgtgatctgg ggcgattact tttatgtaga aggaatcact cgtctagcta
    16501 aaacatggta ctgttactgg tgatgtataa gagaagagga ggattcatat aatgaagcga
    16561 tggaaaaaaa tgatgattgg atcaatagtt ttaggaatgt cactcgtatt tggtgcttgt
    16621 ggtaatcaag aagacagtag tgaagaatca gcaaatgaaa ttaccgtttc gacatggaat
    16681 tatgaaacaa cacctgaatt caaagcgctc tttgaagcat tcgaaaagaa aacgggaatc
    16741 aaagtgaaag cagtagatat tgcttcagat gattatgata cgaaactcac cacgatgctt
    16801 tcttctggag acacgacaga tgtattgacg atgaaaaatc ttttgtcgta ttcaaattat
    16861 gctttacgag atcagttagt cgatcaaaca gaacgaatta gagaattaga cactgatgct
    16921 gctgaagaaa catatgaaat gtatgatatc gatggaaaaa catatgcatt gccatatcga
    16981 acggactttt gggtactata ttacaataag aaaatgtttg atgatgcagg aatcgaatat
    17041 ccaaaaaatc taacttggga cgaatatgaa gatttagcaa aaaaacttag taaaaatgac
    17101 ggacaagttt acggagcata tcaacatatc tggcgttcga caatccaagc tattgcagct
    17161 gctcaaaacg aggcgaatct tgttgaacca gattatcaat atatgactga ttattatgat
    17221 cgagcattga ggatgcaaaa agaaggcgcg cagatggatt ttggcacggc taaatcaacg
    17281 aaagtaacct atcagtctca atttgaagaa caaaaagcag caatgatgta catgggaact
    17341 tggtatatgg ctggcatact cgcaaacaaa gaagcaagta agacagaagt agaatgggga
    17401 attacagcta ttcctcagaa gaaaaaagga gaatcggtca cgacgtttgg ctcaccaaca
    17461 gcatttgctg tcaataaaaa ctcaaagaaa caaaaagcgg cgcaagaatt tattgaattt
    17521 gcagccagtg aagaaggagc aaaagtatta gcaggagtag gagtagttcc ttcatatcgt
    17581 acggatgaga ttgatcagct ttattttaat ctcgctggaa tgccaacgga tgaaatttct
    17641 aaaaaagctt tttctcctga tgaaatcaaa cttgaatttc cgattgatac gtatgggcct
    17701 gcaatcgata agattttaca agaagaatat gacttagttt tggttggaga tgaaacgccg
    17761 gaaaaaggaa cggtaaatat ggagaaacgt gtagctgcgg aaaaagaata atcatgaaag
    17821 gagagaagcc aagagataaa acactcttgg tttcgtcatc gaaatggaga atagtataaa
    17881 taagaaagct acaaatcatt tgcgtagaaa acgaacgtgg atcgcttatt cgtttatcgc
    17941 cccgaatttc attggttttt tcgtttttac attaatacca atcctgtttt cgcttgtact
    18001 agcatttatg aaatgggatt ctttttcaac gccagaattt gctggactag ataactttcg
    18061 taaaatggcc aacgatgaga cattttggat ttctttgaaa aatacttttt tatataccgc
    18121 tgctgtagtg cctggcacac ttgtttgttc gttagggcta gctttactac taaatcagaa
    18181 aattagaggg atgaagcttt ttcgtacgat atttttcttt ccgtatgtta cttccttagt
    18241 agcaattgct gttgtttgga atatgttgtt tcatccaaca gtgggaccta ttaatatctt
    18301 tttaagacga tttattgaac atcctccagg ttggacttca agttcaaatt gggcgctttg
    18361 ggcaattgta attgtcagta tttggcgagg gatgggttat tacatgattc tataccttgc
    18421 aggactacaa agtatccaaa aagaactata tgaagcgtct tcgctagatg gagcaaaccg
    18481 ttggaaacaa tttttgaatg tgacattacc ttcgttgaga ccaacaacct tctttgtaac
    18541 gatcatgctt gtcatcaatt gtttcaaggt gtttgacctt gtgcaagtga tgacggatgg
    18601 cggccctggt cgagcgacaa atgtgctggt ttaccaaatc tacaatgaag cattcaaaaa
    18661 atttgatttt ggttatgctt cagctatttc acttgttttg ttcgtaattg ttttgggcgt
    18721 tacggttgtt caattttctt ggaataagcg tcgtacttag gaggtgtgat atggaagaga
    18781 gtgttcgaaa tgaaagaaaa aaagcaaaaa ttcgttcaaa aaacatgccc tttattcaat
    18841 ggttgggtat gattctgctg attgtattag ctttattgac gatcattcct tttttatgga
    18901 tggtttctgc ttcattcaaa gcaaataatg aagtgttaac gattccgatt caatggatcc
    18961 ctaaaacttg gcatttagag aattatctgg ttatttggtc tcgtattcct ttagtgacat
    19021 tttttaagaa tacagctttt ttaagcgttg tgatcacgtt gattcagttg tttacttcta
    19081 gttttgctgt ttacgggttt tctgaactaa attttaaagg gcgcgatatt ttatttttag
    19141 catatatcgg cacgattgct gtcccttggc agtcttatat gatcccgcag ttcattatga
    19201 tgagaaaagt gggtttaaca gatacgttgt ggtcgttggt gctattacaa gcgttcaatg
    19261 cttttggtgt gttcttgttg aagcaatatt acagtagtat cccagattct ttatgtgaga
    19321 gtgcgcggat cgatggctta tcagagtggg aaatctatcg caagatcatt ttacctctta
    19381 caaaaccggc gattgccagt ttgacgatca tcacattcgt taatacatgg aacgattata
    19441 tggggccatt catttatttg tcttctacgg aaaataaaac aatccagtta gggttgaaaa
    19501 tgtttattgg gctatttgat gcagagtacg cattaatcat ggctgcctca gttgtttctg
    19561 ttcttcctgt tgcttttata tttttagcga tgcaaaaata ttttgtagaa gggatcgctt
    19621 catcaggaat gaaggaatag gaggtgatta tgaaagagca gcgttttgac aaaaatgttt
    19681 atatggaatt cttttattgg ttgtatcaat cattggcaag tagcctttgt ttttggtgtg
    19741 tcaatatctt gtatatagca gctgcgttcc ttttgtcgat agatggaagg aatgtctttt
    19801 cctttatttt ttctttactt tttattggtc caggttgcat cgtgatgata ggtatgacag
    19861 aagaattagc aaaagaaaaa agtttttcac cagtacgttt gttcataaag acgtttcgcc
    19921 aattttggct aaagggattt ttttattggc tatttgcttg gatagttagt gtgataatga
    19981 tttttgattg tttctttttt atacgttttt cttatggaaa atggttgatt ccgttgtttg
    20041 ttttacttgc ttgttttact tgcttgttta tcagtttcct ttagcatcaa ctgctggtat
    20101 tttcaggtga gaaatccagc gtcgaaacca aatcaagttc tacggatagc gttctactat
    20161 acgttgaaaa aatggtatgt gagtttacta gattttttac tattgacaag tttgtttctc
    20221 ttctttttcg taaagcccca atggtgtatt ctactaggtc cttctatcgt atttggtttg
    20281 atttacttca acaatcgtaa attgatgaga actatggatc tgtagacttt ataaattgaa
    20341 actttcaatt aagaatgaca gttttttatg taaaaactgt cattcttttt cattttttga
    20401 aacatatggc taaacaaatg aaataaaaca tgctatactt ttgaatgaaa caggtttaga
    20461 aactgtatca cttatttgtg attatttcta actaataatt aaaaataaag cataaaaagg
    20521 acgatgttca atggctgaaa aaatgaaaca aggttcgaaa tctgtagtag aaagtttgat
    20581 taatcatcat gttgattatg tattcggtat accaggtgca aaaatcgatg gtgtatttaa
    20641 tgaattagag gatcaaggtc ctgaattaat cgtgactcgt cacgaacaaa atgctgcatt
    20701 tatggcacaa gcaatcggac gtattacagg agagccagga gtagttatcg caacaagtgg
    20761 tcctggtgct agtaacttag ctacaggttt ggtaacagcg acagcagaag gtgacccagt
    20821 tttagcaatt gccggacaag taaaacgaag cgatctattg aagttgaccc atcaaagcat
    20881 ggataatgca gcactgttcc agccaatcac aaaatacagt gcagaaatcc aagatccaga
    20941 aacaatttca gaagtgattg ccaatgctta tcgtatggct aagagttcaa aaaaaggcgc
    21001 gagctttatc agtatcccgc aagatgtagt ggatgcacct gtccaaggta atgtcatcaa
    21061 gccattgagc gatcctaaat taggttctgc ttctgcagat gatatccgtt acctagctga
    21121 acgcattaga gaagcaaaac taccggtact attagtaggt atgcgaggat caagtgaaaa
    21181 agaaacgtta gccatcaggc aattagttga aaagacagca ttgcctgttg tagagacatt
    21241 ccaagcagct ggagtgatct cacgtgaatt agaagcgcat ttctttggtc gtgtgggttt
    21301 atttagaaac caaccaggag atatgctttt gaaacgaagt gatctagtta ttgcaattgg
    21361 ctatgatcca atcgaatatg aagcaagaaa ctggaatgcg gaaaaagatg cgcggatcat
    21421 tgtgatcgat gaagcgccag ctgaaatcga tccttttatg cagcctgaaa gagaattgat
    21481 cggtgatatc tcagccactc ttgatttatt gacaggttca ttagagcctc aacaagtgtc
    21541 agaagatgca aaagaatatt tagcatctct tcaagcaaaa ttaacggagc gggacattgt
    21601 tcaatcaaaa ggagaagcag gtatcttgca tcctttagaa gttattaaca cgcttcagtc
    21661 aaaagtaaca gatgatatga ctgttaccgt agatgtaggt agtcattata tttggatggc
    21721 acgccacttt agaagttatg aacctcgtca tttgttattc agtaatggta tgcaaacgct
    21781 tggtgttgca ttgccatggg cgatttctgc tgcattggtg cgtccaaata cacagatcgt
    21841 atcagtttcc ggcgatgggg gatttttatt ctctgcccag gatttagaaa cggcggtacg
    21901 taaaaaattg aatatcgttc atttgatttg gaatgatgga cactacaata tggtagagtt
    21961 ccaagaaaaa atgaaatatc agcgggcgtc aggtgtagac tttggtccag ttgattttgt
    22021 gaaatatgca gaagcttttg gcgctaaagg aatccgagct acaagtgtag aggaattaga
    22081 aaaagcttta gaagaaggat ttgcgacaga aggacccgta attattgata ttccgattga
    22141 ttaccgtgat aatgagaaat tgggagaaac aatcttacca gatcaattct attaaggaag
    22201 tgtcgacatg actgaaaaaa tcttatacca gcacgggaca ttaggagctt tgatggccgg
    22261 cttgatggat ggaacagaaa cgattgctca tatattagaa aaaggaactc tgggattggg
    22321 aacattgcat gggcttgatg gtgaagtcat ctttttagat ggcgtagctt atcaaggaag
    22381 atcagatggc tcagttgccc aattagatgg aagtgaactt accccctatg cagcaattac
    22441 agattttacg ccagatacta gtttttctgt ctcaaaaact gcagatggag aacaattgaa
    22501 aaaagacata ttagtaagag aagccgggga aaacctattt ttggcagtga agataactgg
    22561 attattcaaa aatatgcaca tccgtatcat gccgaagcaa gaaaaacctt acagaagact
    22621 agcaaaaatt tcagagtctc aaccagaatt ccaacaaagc aatgtccaag gaacattagt
    22681 cgggttcttt acgcctgaat tattccaagg agttgctgca gcgggatttc acctgcattt
    22741 tatcgatgat acacatacat ttggcggaca tgtaatggat tttgaagtgg ctgaaggaaa
    22801 agttgagatt agccgcatct cgtcccttgt acagcatttt ccagttgatg atccgacttt
    22861 tgttcacgaa acgattgatt atgctgattt agcagcagaa atccaacaag cagaatagaa
    22921 aaagacagcg agatgcgttc aaggtgatta acctgacgta tctcgttttt ttgaggagaa
    22981 aacctagcgt ttacaaaaaa actgagctat aatcttctcc atagatcaaa aaggagcggt
    23041 ttttatcatg tggacagaaa aacagaaaaa agatgcatac gaaattttat tattacagca
    23101 acaaggatta ttagaagcag aagataactg gttagcaaat ttagcaaatt catctgcatt
    23161 gttgaatgag actttgcctg agactgtctt tgcaggatat tatttattcg atggtaatga
    23221 attgatttta ggaccgttcc aagggcgagt ttcttgcaca cgtatcaaga tgggaaaagg
    23281 agtttgtgga gaatcagctg aaaaacaaga aacattgatc gttgatgatg tcaaaaccca
    23341 tgcaaattac atttcctgcg attcagccgc acaatcagaa atcgtagtgc caatggtaaa
    23401 agaaggtaat ttaatcggtg ttttagatat cgattgcgga gtaacgaaag ggtatgatga
    23461 aatcgatcaa gcatttctag aaaaatatgt agatctttta ttagcaaatt ttaatataaa
    23521 tgctttttca tttattaata actaaaatcg tctattgaaa caaaaaagaa gagaaatcaa
    23581 gaataaaaag agccggaaag acagtgggca tttctgtttt tcggtttttt tattttttta
    23641 taaaatcaca agtgttattg attttcataa tcatatttta atgttattat cattttaaat
    23701 aatgaaaaaa cattaaggat ggatgaaata tgaataacga aactatcatt ttaggaaaaa
    23761 aatatatttg ccaacctatt ggcttgaaac aaaaagtgat tggagaagta atcagtaaat
    23821 tagaaaattg tgttgtgatc tgcgtagacg aatatcatga cgtcgatcgc aatgaaatat
    23881 tagaaaaatg cggaaaagta gtggcaaaat atactcacgt ttatgagttg gaaacaacag
    23941 aatatctata taactatagc aacaaatatg aacatacttt agtttcataa agatttaaat
    24001 aaagtgcctt caaaagcgag aagaccaagc ttttgaaggc actttattta gttggcagtg
    24061 attgttcatg atttttgatt tattcaaaag gttcgcctag agaatctgtc tctgtaacga
    24121 ggcctggtgg agaaactcga taaaaaccta tactgccaga actgtcctat tttcggatag
    24181 acaaactagt agttttaaaa agatcatccg atccaatcat ttcaaaaaat gcaaaactga
    24241 tatcaggatc atttagctca ggcttgttat cgtaaagcat ttgtaaaggt tgcatttagt
    24301 taggagtaaa cgcgaaacta tcatcattat ttgctgaaga agatgaagaa gctaattcag
    24361 agtttgtttg aaataaagga gacgtgctga cagtttcttt accctgtttt ttgcagaggt
    24421 agaaactttt atatcggaag tttctaccgg agaatttttc tcatttgtag aaattgttga
    24481 atcgatacta ttcgaaattt gcgtatctga aggtatgttc tttgatgcag aagtcccaca
    24541 agcagtaagt aacaataaat ttgataaact gataaacaga attcttttca ttatgtacac
    24601 actccttata gtatcgttta gcatacacct atgctcagta ttaggcaaaa tcaatgcaaa
    24661 actatcaagt cttttatagt atctattagt cttagtaata catatatgga gagggtgata
    24721 tcccagttca aaccagatac attggttacc atctgtatta acgattatgc ctctaaacgc
    24781 tttttttatg aaaaaattta taagtgaaaa cgtaggtatg atattatcta gaggtaattt
    24841 ttttgggtat ttaaatagtt gctaggagga tagcttttgg atttttacag taattttatc
    24901 ttaataatag caatattatt acttctaaat atttggtttt ttgataagag tagaaatgca
    24961 gggataggtt ttagaaccaa acgaagtacg tcttctgaaa aaaagtgggt atattcacag
    25021 actatttttt acggaggggt tatttcaatc agtttacttt cttcaacact ttattctttt
    25081 aatgttatag acgtttccat gtcaaatttt atatctatta ttggaatcct tatttctgca
    25141 attattacac aactacttct tgtgtttgaa gagaagtcaa aaaataatta aagcaattat
    25201 gccttttagt acaggaatta ttacttctta caaatgtata gcgaatgtga agcctgctgt
    25261 tttaattgtt ctagaaaaac ttttgagtga acaattattt tatgttagga tgaattaatt
    25321 tctctagagt ttataattcg ccgtttgtat aattaagcga gacaaataaa aaagccattt
    25381 atgttacact c
//
LOCUS       DACGLI010000045        25242 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.046, whole genome shotgun sequence.
ACCESSION   DACGLI010000045 DACGLI010000000
VERSION     DACGLI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.046"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            5..1087
                     /locus_tag="IXT22_002010"
     CDS             5..1087
                     /locus_tag="IXT22_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4863347.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="IXT22_002011"
     CDS             complement(1305..2447)
                     /locus_tag="IXT22_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4863348.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="IXT22_002012"
     CDS             complement(2452..2637)
                     /locus_tag="IXT22_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4863349.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="IXT22_002013"
     CDS             complement(2991..3236)
                     /locus_tag="IXT22_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4863350.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="IXT22_002014"
     CDS             complement(3230..3631)
                     /locus_tag="IXT22_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4863351.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="IXT22_002015"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="IXT22_002015"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAQ4863352.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="IXT22_002016"
     CDS             complement(5649..7415)
                     /locus_tag="IXT22_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAQ4863353.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="IXT22_002017"
     CDS             complement(7428..8222)
                     /locus_tag="IXT22_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4863354.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="IXT22_002018"
     CDS             complement(8232..9608)
                     /locus_tag="IXT22_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863355.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9728..10375)
                     /gene="eda"
                     /locus_tag="IXT22_002019"
     CDS             complement(9728..10375)
                     /gene="eda"
                     /locus_tag="IXT22_002019"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4863356.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="IXT22_002020"
     CDS             complement(10459..11886)
                     /gene="uxaC"
                     /locus_tag="IXT22_002020"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4863357.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="IXT22_002021"
     CDS             complement(11960..13039)
                     /gene="uxuA"
                     /locus_tag="IXT22_002021"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4863358.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13042..14673)
                     /locus_tag="IXT22_002022"
     CDS             complement(13042..14673)
                     /locus_tag="IXT22_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4863359.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14977..15648
                     /locus_tag="IXT22_002023"
     CDS             14977..15648
                     /locus_tag="IXT22_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4863360.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(16373..16708)
                     /locus_tag="IXT22_002024"
                     /pseudo
     CDS             complement(16373..16708)
                     /locus_tag="IXT22_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16805..17257)
                     /locus_tag="IXT22_002025"
     CDS             complement(16805..17257)
                     /locus_tag="IXT22_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863361.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(17264..17812)
                     /locus_tag="IXT22_002026"
     CDS             complement(17264..17812)
                     /locus_tag="IXT22_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4863362.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(17857..18189)
                     /locus_tag="IXT22_002027"
     CDS             complement(17857..18189)
                     /locus_tag="IXT22_002027"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863363.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18203..18433)
                     /locus_tag="IXT22_002028"
     CDS             complement(18203..18433)
                     /locus_tag="IXT22_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863364.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(18655..19197)
                     /locus_tag="IXT22_002029"
     CDS             complement(18655..19197)
                     /locus_tag="IXT22_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863365.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(19218..20309)
                     /locus_tag="IXT22_002030"
     CDS             complement(19218..20309)
                     /locus_tag="IXT22_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4863366.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20317..22527)
                     /locus_tag="IXT22_002031"
     CDS             complement(20317..22527)
                     /locus_tag="IXT22_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863367.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(22543..25071)
                     /locus_tag="IXT22_002032"
     CDS             complement(22543..25071)
                     /locus_tag="IXT22_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4863368.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
BASE COUNT         8057 a         5079 c         3438 g         8668 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaac tagaaaaaaa acataaaaat
     3721 atttatcatt ctttaaacag aaaatctttc tataaaaaac aaaaaaaaac gattaggcta
     3781 ggctaatcgt tttttgaaca ttcttaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt aagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgacttgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttcca
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 catctggcgt tgattttaga taagtaacga ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcgtct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taataaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaattctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggtac aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagtgat aattccttta
     6421 cgatagcctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat tgaaggtaat
     6721 ccagcttcta ttaagcctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta atagaggaat tttactttct gtttgtaaga tatagttttg atcatatacc
     7201 tcatcagcag ttcctggatt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaaatc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tatatatttt tgttcaatat ctacataatc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attgaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatatcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc ttttgcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 gaatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatcga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttatg tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa tcagaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtac atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agcttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 tattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgacc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttctgttgt taagcgtttt cattctgatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctat acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat gactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctccttcct ttatggatac atactttgtc tagctgtact aacttacaaa gaataaattt
    10441 aagcttttat ttcaagtatt attttctact tccgatttca aaaaaattaa aataattata
    10501 cgcattacga taacaaatat tctccactat ctgactaaga tacatttcat catctggaat
    10561 tcggcctgct ttaacccact cgcttagtaa ttgacataat actcgacgaa aatactcatg
    10621 gcgaggatag cttagaaaac ttcgagaatc agtcaacata cctgtaaaat tcgacaacaa
    10681 actttgttgt gccatcgtag tcaactgttg acgcattcct tcagctgtat cattgaacca
    10741 ccaagcacat cccaattgga ttttttgaat cataccccct tggaagcttt gcattgctgt
    10801 tgctagtgga agccaatcag ttggatttaa tgaatataaa attgtttttg gtaagcaccc
    10861 actcttttca gcggtatcga acaatgctac aacattttgt gtcaaactag cttgatcccc
    10921 catcgaatca ccaccgacat ctactccaat ttgttccttt aatatacttg aattatttct
    10981 taaagcattt aaatgcattt gcatcgtcca accatatctt gtatactcag acatcaaatg
    11041 taattgaata cctgtaacaa attgtgcaat ttctgataaa tggaaatccg tttttcctgc
    11101 taaagctttt attaacagat tgtcgagtat tttttcatct gctatttcat aaaaataagt
    11161 attcaaaccg tgatctgcta atcgacagcc aatttgatga aaatgatcca ctcgttggct
    11221 caatgcttgc ttcaacccat taaagtcttt gattggtata gccgctgttt gactaagttt
    11281 taaaatatag ttcgaaaagc ctgatgattt gatactccag accttatctg gacggaaagt
    11341 aggtaatacc ttgaaagaat tatcctgttt agaaagctca gtatgatacc acaagtcatc
    11401 tgtaggatca tccgttgtac agatggcttt cacatccatc atctccaaca attctttcgg
    11461 gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc caaatttctg gtgcattctt
    11521 ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat tccaaatgag accattcaaa
    11581 aataggatta cctggcgcct tctccactgt ttttacaaaa gctaaaaatt tttcataatc
    11641 atcacctgga ccactgatca actcttcttc tataccatta gctcgcatca atcgccattt
    11701 ataatgatct ccagctcctt tatcatttaa ccatacctga gtcaaattct tgtattgctt
    11761 attttctagc aaatatgctg ggtctaaatg acaatgatag tcgataattg gttggtgttt
    11821 tgcaaattta tgaaaaagtc ttttagctat ttcattctct aataaaaagt tcttatctaa
    11881 aaacatattt aaacactcct ttccttccgt tagtttttag aagagaaaat ttttcctcta
    11941 aataaactcc cttatataat tatttactcg cccccttttc aagcgcttcc caaataccat
    12001 ttaaataaac tgcacctaga gctcggtcat ataatccata accaggtcta ccggtttctc
    12061 cccaaatcat ccgaccatga tctggacgaa tatagccatt aaatccatta tcgtacattg
    12121 tttttaatat cttatacata tctagagaac catattctga tttatgcggc gcttcgtaaa
    12181 aatcgagtcc attgtcactt aaatatttga tattacgaac atgtgcaaaa ggaatccgat
    12241 cccgttgaca aaattcagat agaatttcat agacatcatt atctggtcgt tctgcaatac
    12301 ttccagtaca taatgtaata ccattagaag gagaatccac tacattacac aaccaatcta
    12361 aatcgtcacg atttttaaca atacgaggta atccgaaaat ggaatatggt ggatcatctg
    12421 ggtgaactgc cattttaatc ccaacttctt cacatgtcgg gataattgct ttgagaaaat
    12481 atgcaaagtt ctctcgtaat ttctcttcat caacttcttt ataggcttct aataattgct
    12541 taatttgtga taaccgatga ggttcccaac ccggcaattc aaaattatta gtagaatttt
    12601 ctacttctct aataatttcc tccggatcag tagggatatt ttttgaaata taggctaacg
    12661 tagaagaccc atcatctaaa cgataatcca aatccgattt tacccaatca aatactggca
    12721 taaaattata acagataacc tcaatcccaa attctgccaa attgcgaatc gtctgtttat
    12781 aattctcaat gtattgatct cgtgttggta aaccaatttt gatatcatca tgaacattaa
    12841 cactctcaat aactttcaag gtaagtccat tggcttcgac ttcatctttt aaagatttaa
    12901 ttcgttctct cggccaaacc tctccggctg gtatatccat taatgttcca acaattcctt
    12961 tcattgctgg gatctgacga atttcttgta gtgagatttt ttcttcattt gccccatacc
    13021 atctaaaagt catttccata gttactttcc tccaacttct gttatatatt tattgattgt
    13081 tttacgaact gcttgaggac ctactagcat ttcgcaaaag attttttcag ttttctttcc
    13141 taccccaact tgatataaat ctaaaccaaa gatttcttta ttttctaaaa tttcctgtac
    13201 cgcacaatga atctttgaag gatcttgttc acctaatttc aatactgata atttatcctg
    13261 caactctacc aataacggat caggacttgg cacaaaattt tccccttgat catcgactgc
    13321 cagtaaataa cgtaaccaag cagcaatagc gataggaata aatgttagat tttctgcatt
    13381 tccgtctttt tcgacatact ttttaattgt ttcaccatag cgaatcgcta ctttttgaga
    13441 agtatctgtt gcaattcgtt gtggtgtatc tggaatatag ggattaggca aacgtttatt
    13501 aattacttca tcaataaatt gttttggatc aataatgcct ggattttcaa ctactggtaa
    13561 accttctaaa taacctattc ctttgattaa accaaccaaa tcatcatcct gcatctctgc
    13621 tgaaattgat tgatatccta gcagacaacc tgttactgcc aaagcagtat gaagtggatt
    13681 caagcttgtc gtaaccttca tgatgtctgc tttatcaacc gtctctctat ctgtcataat
    13741 cacaccagcc ttttccaatt taggccggcc atttggaaaa ctatcttcaa taactaaata
    13801 atgaactacc tcagtattag tgaaagcagc aatattggta tgtttttttg tgtgaatgat
    13861 atctaaatcc tcgagcccca tcatcaatag atcttccttt acattctctg aaggatttgg
    13921 cgtaattcga tcaatcatac tccaaggaaa agtcactttt tctttatcct ttaaataagc
    13981 aataaatttt tcagaaacat atccttcttt ttgccaagct tctgcaatcg taaaaatact
    14041 atcttgaaaa cgttgaccat tctgtgagaa attatcagta gaaaccatcg caatcggcaa
    14101 ctctccagca ttaaatctgc tatataacaa ggatgttaca atactcatcg tatgttgagg
    14161 attgctaggt ccagatttga tatcagcttt gactaccgaa aagaattgcc ctttagaatc
    14221 ttttaaactg taaccttttt cagtaatagt aaacgttgta aactgtaatt taggatcttc
    14281 aaaatattta accactcttt gatagtccgc tatattcttc ggattgcaat ataaactatc
    14341 agccgttact gccaaaagtc tttttttgag ttcaccatct ccactcataa caatttccaa
    14401 aatgtcattg ttatagtcat gataagcttt ttccactact tcttcatcaa atgtttcaca
    14461 cacaactact cctgtttcta attcattttg atctgctaag cattgagcaa tttctgcatg
    14521 aaatcctcga taaagatttc ctccaccaaa atgaagccat actggatgtt gctggccttc
    14581 ttgcttaact tctttgacat caaaacacgg cagtagaatc tgcatttcat tgaattcttc
    14641 gatagaattt tgccaatttt taatcgaaac cataattaac ctcctcaaac tgatatgtta
    14701 gttttgatac attttatatt ttaaaaccca ttgtaaccgt tgtcaatata aaaagggaat
    14761 aaacttgctt ttttctacca tatcagaatg attgtatttt ttattcagaa aaataaaata
    14821 ctccttcttt ttggactgat tttatcgaaa cttatttttt ctttttttca tgtattcttt
    14881 tatttttata actagtgtat tacttcaaaa tttgatatta tatggcatga acagaattaa
    14941 aatatcagtt aaaataaaag ttaaggagca ttgtgtatga caattaaaac tagtctccaa
    15001 aatcaagctt accaatctat tcgccgacaa attatctatg ctgacttaga acctggaaaa
    15061 aaagtatcag aaaaaaaatt agaagaaaca ctttctattg gtcgtacacc aatacgtgaa
    15121 gcactgattc aactccgaca acaaggtctt gttgatacaa ttcctcaaag cggaaattat
    15181 atctcattaa ttgatttaga ttcggccaaa aatgctcgat ttgtcagaga acatttggaa
    15241 cgacaaatta tgttagagtg ttgtgccaaa atgaataacc aaaaaaaacg gattttagaa
    15301 actataattt cagaacaaga aaaagctgtt agtcaaaaaa atgctcgtag tttttttcat
    15361 aatgataatt tattccataa agcttgtttt gaaattgcag agcgagaaga agtatggcaa
    15421 tggttagaaa ataacaatac acacttagaa cgatttcgat ggctacgagt aaaaacggaa
    15481 ggattaaagt gggaaaaaat tatggaacaa cattatcaac tatttgaggc attaacaaaa
    15541 caagatccag aagaagctaa ctttctaaca tcgttgcatc ttcatttaat gcttaatgag
    15601 caaaatattg ttttagctac tcatccaaaa tatttcaaaa atatataact tttaactctt
    15661 tttaaattaa atggttgttc tgatcagaaa aatatcgctt gttttcttat tatgtaatat
    15721 atttcataaa ctattctgca taacaactat tgtttgtact ttttacattg gataactaat
    15781 tatgactgct gataactttt gatattaaac tagtatctcc aatacaaata aaaaatagat
    15841 atcttgttca tcaaaattag ttcgtggata cttaccttca tttacatcat tcagcggttt
    15901 cccattttct tttattctat tatttcattt tctaatagac ttggcttcat ttcgcaatac
    15961 tttttttcaa taggcatcaa attggtgttg tttagatatt tagttgtagt tttgtgacat
    16021 gataagtatg ctcctttttc tcttttccac taatacaacg atcaaagggt gcttttttca
    16081 aaaaactaga aaaatcaaaa taagattcgt attttgattc tatatatcct gtttcaacta
    16141 catcttatat ttcacaatag aataaatagc cttttgcata gctgcttaac ttataagaaa
    16201 ttgcaattta cttcttcaaa gtgaaaacga atatgagtaa aataaaatta ttcttcttac
    16261 agataattaa aaatagcgcg taacaaaaat cggcattcaa tcacataatt aggattgatg
    16321 ccgattactt atattctacg tatagtttta gtattcttat tttttatcac cagtaaccaa
    16381 ttgagaacag ccctaaagca gaatagtctt ttatctcaaa acgcttaatt tcaggcttag
    16441 gaatatgaat aatcttttga gtatattctt tctcttttaa tcttactgaa gaaataccac
    16501 tgcctatctt ttttacaaat atttcatttg gtgtacagac taataaaaca atatttgtaa
    16561 tcaatccttg cactaaagaa ttaaaaggaa gactatttaa aacagggtgt gcataactat
    16621 aacatgtgaa gtagttattt tgaactttaa cttttaaaaa ctttaaaaat aatcttattt
    16681 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
    16741 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
    16801 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
    16861 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
    16921 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
    16981 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
    17041 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
    17101 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
    17161 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
    17221 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
    17281 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
    17341 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
    17401 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
    17461 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
    17521 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
    17581 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
    17641 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
    17701 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
    17761 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
    17821 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
    17881 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
    17941 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
    18001 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
    18061 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
    18121 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
    18181 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
    18241 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
    18301 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
    18361 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
    18421 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
    18481 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
    18541 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
    18601 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
    18661 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gatctacttt
    18721 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
    18781 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
    18841 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
    18901 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
    18961 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
    19021 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
    19081 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
    19141 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
    19201 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
    19261 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
    19321 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
    19381 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
    19441 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
    19501 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
    19561 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
    19621 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
    19681 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
    19741 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
    19801 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
    19861 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
    19921 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
    19981 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
    20041 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
    20101 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
    20161 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
    20221 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
    20281 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
    20341 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
    20401 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
    20461 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
    20521 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
    20581 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
    20641 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
    20701 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
    20761 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
    20821 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
    20881 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
    20941 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
    21001 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
    21061 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
    21121 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
    21181 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
    21241 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
    21301 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
    21361 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
    21421 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
    21481 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
    21541 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
    21601 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
    21661 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
    21721 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
    21781 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
    21841 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
    21901 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
    21961 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
    22021 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
    22081 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
    22141 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
    22201 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
    22261 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
    22321 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
    22381 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
    22441 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
    22501 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
    22561 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
    22621 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
    22681 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
    22741 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
    22801 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
    22861 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
    22921 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
    22981 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
    23041 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
    23101 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
    23161 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
    23221 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
    23281 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
    23341 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
    23401 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
    23461 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
    23521 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
    23581 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
    23641 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
    23701 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
    23761 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
    23821 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
    23881 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
    23941 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
    24001 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
    24061 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
    24121 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
    24181 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
    24241 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
    24301 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
    24361 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
    24421 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
    24481 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
    24541 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
    24601 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
    24661 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
    24721 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
    24781 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
    24841 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
    24901 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
    24961 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
    25021 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
    25081 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
    25141 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
    25201 atacacacaa tcaccattca tcatacgaat catataacaa aa
//
LOCUS       DACGLI010000046        24579 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.047, whole genome shotgun sequence.
ACCESSION   DACGLI010000046 DACGLI010000000
VERSION     DACGLI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.047"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(153..551)
                     /locus_tag="IXT22_002033"
     CDS             complement(153..551)
                     /locus_tag="IXT22_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAQ4863369.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(548..1321)
                     /locus_tag="IXT22_002034"
     CDS             complement(548..1321)
                     /locus_tag="IXT22_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4863370.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1318..2001)
                     /locus_tag="IXT22_002035"
     CDS             complement(1318..2001)
                     /locus_tag="IXT22_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4863371.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2168..3055)
                     /locus_tag="IXT22_002036"
     CDS             complement(2168..3055)
                     /locus_tag="IXT22_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863372.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3052..3921)
                     /locus_tag="IXT22_002037"
     CDS             complement(3052..3921)
                     /locus_tag="IXT22_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863373.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4058..5344)
                     /locus_tag="IXT22_002038"
     CDS             complement(4058..5344)
                     /locus_tag="IXT22_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4863374.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5617..6195
                     /locus_tag="IXT22_002039"
     CDS             5617..6195
                     /locus_tag="IXT22_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4863375.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6195..7124
                     /locus_tag="IXT22_002040"
     CDS             6195..7124
                     /locus_tag="IXT22_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863376.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7121..8857
                     /locus_tag="IXT22_002041"
     CDS             7121..8857
                     /locus_tag="IXT22_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4863377.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="IXT22_002042"
     CDS             complement(8920..9756)
                     /gene="pheA"
                     /locus_tag="IXT22_002042"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAQ4863378.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9753..10262)
                     /locus_tag="IXT22_002043"
     CDS             complement(9753..10262)
                     /locus_tag="IXT22_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAQ4863379.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="IXT22_002044"
     CDS             complement(10255..11550)
                     /gene="aroA"
                     /locus_tag="IXT22_002044"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAQ4863380.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11563..12654)
                     /locus_tag="IXT22_002045"
     CDS             complement(11563..12654)
                     /locus_tag="IXT22_002045"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAQ4863381.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="IXT22_002046"
     CDS             complement(12671..13837)
                     /gene="aroC"
                     /locus_tag="IXT22_002046"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAQ4863382.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="IXT22_002047"
     CDS             complement(13839..14903)
                     /gene="aroB"
                     /locus_tag="IXT22_002047"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAQ4863383.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="IXT22_002048"
     CDS             complement(14936..15958)
                     /gene="aroF"
                     /locus_tag="IXT22_002048"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAQ4863384.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16617..17591)
                     /locus_tag="IXT22_002049"
     CDS             complement(16617..17591)
                     /locus_tag="IXT22_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAQ4863385.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17572..19455)
                     /locus_tag="IXT22_002050"
     CDS             complement(17572..19455)
                     /locus_tag="IXT22_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAQ4863386.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19473..21698)
                     /locus_tag="IXT22_002051"
     CDS             complement(19473..21698)
                     /locus_tag="IXT22_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4863387.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21813..22847
                     /locus_tag="IXT22_002052"
     CDS             21813..22847
                     /locus_tag="IXT22_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863388.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22914..23927)
                     /locus_tag="IXT22_002053"
     CDS             complement(22914..23927)
                     /locus_tag="IXT22_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863389.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24005..24193)
                     /locus_tag="IXT22_002054"
     CDS             complement(24005..24193)
                     /locus_tag="IXT22_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAQ4863390.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7065 a         5341 c         4397 g         7776 t
ORIGIN      
        1 agcatatttt gaaaagaaag tctgatgctt agagtagaat ttcataaaaa tttactattt
       61 cataagtatt cacgagaaaa atacaaacaa aaaagcggaa ataacgctca tccgccttct
      121 tgtttgtgtt tatttcctct tcaaacgctt gtctatgatt cagacttttc tctatcgtta
      181 ttttcatcta aaagttcttg cattccgata atttctcgat attgatgaat cttagtgata
      241 ccaatgactt tgtctacatc aatactaaaa caaataccat tacctggaat atcgatgttg
      301 atgccttgac caatcgcatc cattacttta ttcgtcaaac tatcgggtac taatgtcaac
      361 acaatatctt tttctggcga aatgtccaaa cctaaaaatt tccctgaatc atgtacacca
      421 gaacctcttc catgtaagat cgttccgcct gctgcacctg cttcttttga aaagtcgata
      481 acatcttcgc ccattcctcc gtcaacgatc gtcacaatca tgtgaagatt caatgctaca
      541 agatctttca tttgctttcc cccaattttt gcaatctttc tttttcgatt ctgtcttttt
      601 catcttttcg tttataaata tatcctagta ctaaagtgga taatattggt gtcaatgcaa
      661 tcattgcaac cacaccaaac ccgtcaatga tcggatctct tccttcaatt tgtgcagcga
      721 ttgccacgct cattgataaa ataaatgtcg aacacatcgg gcccgttgct actccaccgt
      781 tatcaaaagc cattgctaaa aagatcttgt ccacttttcg tcctaaaata aatgctagcc
      841 cgtatcctgg gatcaagaaa taataaagag agaatccgac gagcaaacgc cacatagaca
      901 atcctactgc tgcgccgatc ccaattgaaa ttaccatcag catgattttc gatcggattc
      961 tcccctcgct caattcttca acctgtttga tcattacatg aatcgccggc tcagcaaacc
     1021 ctactaagaa ccccattaaa aagccaaggg gaaccagtat ataattgtaa ggcaatcccg
     1081 caatagcact gcctaaatgc tgtcctaccg gtacataagc catattgact ccgtgcagga
     1141 aaaggatcaa cccaatagtc gttatcaaga aacctttcat aatgtcaaag aaacgctttt
     1201 tgcgcatacg aaaactaatg atattcatta aaacaaatag gattacgata ggtgccactg
     1261 ccaaaatgac ttccatggta acgatttcga ttccatctat cacttgctgc cagaaactca
     1321 ttggaagatc acccccaaaa tcatcacggc aagaatcggc cctaacgaag caataccgac
     1381 cattccaaaa ctgtcatttt catttttctt ttgtttgatc atactagtca tccctccggc
     1441 aagggccaag ataaatggaa cagttactgg accagtagtc actccccccg aatcaaaagc
     1501 aatcggcata aattcggaac tggtgaaaaa tgaggcgatc aaaacgccta tgtagcctat
     1561 agccatcaat tgataatagg atagcttgaa tacgacccga agcagcgcaa aggctagaaa
     1621 tactccagtg ccgacgctga cgatcccaat cagcaacact ctgccaatct ctccgtcaga
     1681 tatatcatat acttgttgtc ccaaaacttg cacggaaggt tcagcaatcg tgatcacgat
     1741 cccgatagca aatcccaaac tgaccaaaac ggtcaaactt ttctttttga tcatatattt
     1801 ccctactaga tctccgactt ccatcataga ataatctgct ccaaacaaaa agagcgtcat
     1861 tccgatcatc atgattgccg caccaaccag aaatgaagcg aggtcttctc cttctaacgg
     1921 tgcaaaaaca aacgttaaaa tgacaatcag gacagtcatc ggcaatatag cagcaatcac
     1981 ttctttaaaa ttttttagca tgtatcctcc tcctttactc tttaagttta ccttaaaatg
     2041 aaagagtttt cgagcacaaa cttaaaacgt tatcatttaa tttttctcaa cataaaataa
     2101 cacacgtccc aaaagtatct ttttacttgg aaaaatgact ttgaaggaac gcgcttattg
     2161 tgttttttta ttttacagag ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa
     2221 atacgatggc agttggtaaa gtagcgatga ctaatccagc catgatcatt ccatagtctg
     2281 gtgtatagga agcacccata gcagataaaa caagcggaac cgtccgttta tcaggagatt
     2341 gcaaagctac taagggccat aaataattgt tccagctact catgaatgtg atgattgcag
     2401 ccgcggcata ggtattttta gccgtcggca tatacactct aaaaaaaata cttagttctt
     2461 ttagaccgtc taatcgagcg gcttctacta gatcttttgg aaaagattta acattttgtc
     2521 gaaagaagaa gatcaaaaaa gcagtgctaa cagatggcag gatgacaacc aagaaactgt
     2581 tgattcccaa aaccgttccg ttcaattgtg aaaacattcg atataaaggg atcatcaatg
     2641 ccgcaaaagg aaccatcatc gatagcagta gaatattgaa aattaggtct tttcgtttac
     2701 tttgataaat ctcaaatcca tatcctgcca ttgacgaaat cagcaatgca aacacagtgg
     2761 tcaccaaagc gatcatcgct gaattccaaa gggaacgagt aaaattcagc tcattggaaa
     2821 acaaattttg aaaattgatg atcaagttac tgccaatctt tatttttccc gatgtgatat
     2881 ccacgggtgt attcgtcatt cccaaaacca tccagacaaa agggaaaatg gaaataaatg
     2941 ataggatgct taatgctgta tactttaata ctgacccaat tgtcgaacga agttctaatg
     3001 cttgtttttt gacgttgggg cgttcgattg tttctttttc taccatattt ttcatcgact
     3061 ttctcctcct actttcgttt ggattatcga caatatcaca ataaaggaaa caataacaaa
     3121 ggaaactgct gccgcatatc caaaattagg cgtgaattta taactcaaat tatagatgta
     3181 ttgagatagg gtggtcgttg catttgctgg tcccccgcca gtaatatttt gtacttcatc
     3241 aaaaagctgc aatgtcccga tcgtcgaagt aatggaagta aacaaaatga ttggttttaa
     3301 atttgggatc gtcactttga taaactgctg ccatttagaa gcaccgtcaa tagatgctgc
     3361 ttcataaatc tccgaatcaa tattttgcat gcctgaaagg aaaaaaatca tattgtatcc
     3421 agtccaacgc caagtgatcg aaagaatgat cagaactctc gcccaaattg gatgagtcaa
     3481 ccagccaatc ggtgtgtcaa tcataccaat gcccaacaac aagttgttta caaggccaga
     3541 ttgagaaaat agacttttca tgatcagaga ataactgacc atcgaagtga tacatggaag
     3601 aaagatagcg gttcgaaaca accctttata tttcaacttt ttatcattta aaaggttgga
     3661 aataaaaagt gctagaaaca acatgatcgg tacttgtaca agtaaataca ggaatgtatt
     3721 aaaaaaagct tttttaaaag ttgcatctgt caacatccgc tgataattac ctaacccgtt
     3781 aaatgtcata ttgacagggg gaccactttg aaaagacgtg atcaaagcca aaaccatcgg
     3841 aataaaaacc atgattgata tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt
     3901 gaataaatct ttctgcttca ttcttttccc tccaattcta tcattgatta tctacatgaa
     3961 aagacaagaa agacaatatc tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct
     4021 gatgaaaaag cgaagaaatt cactttttta ccaccgatca attagccaat tgtgcttcta
     4081 cttgtttttg tgtatctgct agtaccttgt ctgtctcttc tccattgatg attcgatgaa
     4141 gagcttcagc tacgactgct tcaattgcat aggtctcatg tccgtaattc acttctggta
     4201 tttcagatgt ccatgttgaa aaatcgtcaa agatcttttg accactgtaa aattcagaag
     4261 cttcttgata agcttcttgt tcattcgcgc taagcatcgt agatactagt ccgatttctt
     4321 tcgcaagagt gcccatcagt tcttcattcg aagcaaacgt tgcttctagg aaatctttcg
     4381 ctgaatcttc tccagctact cctttgatca cataccagcc agcgccgcca aggttagaag
     4441 cttgcgcttt ttgcagattt tctggaagtg caggtattgg tgcaatcttc cattttccag
     4501 attggttttc tgctccttgg atcgttgaag aataccaagc gccagttggg ctagaagcta
     4561 ctgctcctga ttgtatcgca gttactccag cattccagtc agaggtttgt tcgactagat
     4621 cttctttcaa aagagtggca aacaattcaa gaccatactt taaagatgca ttgtcttgga
     4681 tcgtgactgt ctccccatct tcagatgtat accattctcc tgcctgttgc ataatcatcc
     4741 ttactcgacc aaggtcagaa ggattgactt cagcgatttt ctttcccgtc ttttctttga
     4801 catctcgcgc tacttgaata tactcgtccc acttcagatt ctccatatcc tcttctgtat
     4861 aacctgcttc tgccatcaga tccgtacgat agaagtttgc tgttacgccc gaatcgaaag
     4921 gaacaccgta tattttatct cctactttgt ttaccgcaaa tttatacggt gcaaaatgat
     4981 cttcctttac aatagcagac aaattagcga atgcatctgg ataagaagtc aaatagcctt
     5041 gtatcctata atcttcaatc aagacgatat tgggcaatcc ttctgtattc ccgctcgcta
     5101 aagcggtgtt cagtttctga acgatatcat cctgagacat cgtaacaact tctatctctg
     5161 tttcttcgtt ctcataaact ttttttgctt cattcactgc tttgatattg aatgtctcat
     5221 cccacgccca gacagtgact ttttcttctt tgtctgctgt actactagca cttccgcatc
     5281 ctgttaagaa acctgatgct gccgctaaac aaacgactcc agcaattaac tttctgatgt
     5341 tcatttttat ccgctccttt tccatccatt agttgtttac gtttgctaca ttcatcatac
     5401 caaaatttga aaacggtttc tttattattc agatacttca aaaatttctc ctaaaataat
     5461 aaaaaaatac aaatcaacta tgacaaaagg aataatctta gcatctagac caaagatcga
     5521 aatggtgagg tttctttaaa ataaaaatat ccttgcattt tctcctagaa ataagtattt
     5581 ttaaattaca agactattct taaggcgggt aaaaaaatgc caatacgcgt aattcttatc
     5641 gatgatgaac agacgatttt agatggaatg aaacagttga tcaattggtc tgagcacggg
     5701 tttcaattaa tagggacttt ttccagtccg ctgaaagcgc ttgatttttc tttggtacat
     5761 gcaatcgata tcgtggtcac agatgtaatg atgcctgaat taaatggaat cgaattatcg
     5821 cggctattaa aacagcaaca acctgaaaca cagatcctta tcctctctag ctatgatgaa
     5881 tttgatatgg ttaaagattc ttttaaagaa ggcgtcgctg attatctttt aaagcctcga
     5941 ttgagtcctg atttttttct aaattcctta actgccgttt cacaaaaaat caaaaaaaag
     6001 cccaacaaaa gcccaatcac caatcgttat gagcagatct gcgagaatct ttcacagcag
     6061 attgctggac aaactcgtcc attgcttgac cctcttcttt ttgaacacac cttgtttttc
     6121 tgttatatac cgaaaaacgg ccattcagtt caaaacaagg ctctaaacaa aaacagtcga
     6181 tcacccattc attgatggat agcgacgatt cgtttactat ttatcctgtt tctacctttt
     6241 cggaagaatc cggctatgta atcaatactg attccaaaga tacacttagg aagtttgttc
     6301 aaaagtttcg tcaagaagtt tttccaggtg atttttttgt tgtttctgat tcttttgcaa
     6361 tccaagatat caatgaaata ttccaagaga tcagaaattg caccaaagga caacgtttct
     6421 atcataaggg aaagaacctt gcttatcagc atgaacttct tccgttatta accaaccacg
     6481 agcagcaagc aagtagttat ttaacaaaaa tcgttcataa agactacgct ttagctgtca
     6541 aagaacttga gaatttcttc acgacgatat tggaacagcc tattgatcca gcttatttga
     6601 aacatgaggc aatcaatcgt ttctatgcat tactcaacgc tttggctgac gagcatgttg
     6661 ggaatgaaga actttctttg ctcaagatcg cccttccttc tttattagcc gatgctgagt
     6721 atttcgaaga tttttctatt cttgtcaaag aaacacttga gaaactcacc cacttttctg
     6781 caaatgcaaa aaaagacaat ttcgatatct tgactttgat ctacgagttc gtccaggaaa
     6841 attatgagaa agaaatcaat ttacaacttt tatccgaaaa atatcatttt tcatatagct
     6901 atctctcagc catctttact gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag
     6961 tccgtatcag taaagccaag ctctttttga cggaaacacg gcttactttg acggaaatct
     7021 gtgagaaagt cggctatacc gaactgggtt atttctccag agtttttaaa gaagagacag
     7081 gaatgacacc ttctcaatac cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga
     7141 gcatgaactc tttgccaaac ttctgttcat tttgttcatc ggtctttttc tgcaagccat
     7201 cgtcatttct ttgtttattt atcatcgatc aagggatgcc tatatccagc tgttcaatca
     7261 atcgaatgat gtggtactaa aaaagattca atctgaattt gaaagtttga atgatacaat
     7321 cgagaataca ttagccgctt ttgattctaa tccagctgtc aaaagctatt tttccaatga
     7381 tccagcccaa catatggaac agcttcagca actaagaaca atccaaaaaa tgaatgactc
     7441 tctttcaaaa atccatccaa tgatcgatta cgatgtattg atctttggag aaaatggaag
     7501 aacttttgtc ggaaacgaca tgctcactgc cgtatctgcc gattcttttt ttcaatctgc
     7561 gattgctcag agagtgaatg aacgtgctgc tgatacacaa atgctttttg cacaccacgg
     7621 attgactctt cgcgataaga aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac
     7681 attgaatcac gtttacggat atgctgtttt atcgatctca tccaagcaac tagcgaatct
     7741 ttttcaatct gtagtaaatc ctgagatatc gaagatctcc ttcatgaacg aagaacagac
     7801 gatcatcgca tcaaatgaag aaaatacaat tgggagccga tcaatgattt tcaaaaaact
     7861 aacagtaggt gaaacaacga tttcaaatgg acagcagttg acccgtcttc ctctgtaccg
     7921 ccaggattgt acattactca gtcaagtcga tcttcattct ttatctaacc aaatgggcgt
     7981 gatttttccg attattttgt ataatatcgt gacacttgct tttgctggct cattggtatt
     8041 tatgtatttg gatcgacaca caaaatcgat ctaccgcttg attgattcgc taaaacggct
     8101 agaggaagat ggcttaaaag ctactgttcc tgtacaagga agccatgaag tccaattgct
     8161 agggaatacg atcaatcaat tgctaagtaa tgctcagcat cattatgaac agacgatcca
     8221 agacgaaaag aagaaacgtt cgcttgaaat ccaaactatg caagcacaga tacagcccca
     8281 ttttatttat aatacgctga ctagcttgaa atttttgatt tggcagaaaa aaacagatga
     8341 agcagttcaa ggaatcgaca gtttcattac tttactaaga agtacgattg ggaaaaaaga
     8401 agaagtgatt ccagtcaagg aagaaatcaa aagcgtacaa agttacatcg atcttttgag
     8461 tatgcgatat ggcgaaagaa tctcggctaa aataatgatt cctgatgaac tgcagtcatt
     8521 atctatgccg aatatgatcc ttcaaccaat tatcgaaaac gcctatcttc atgcttttca
     8581 caataaaacg caaggattca tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt
     8641 cgaagtgatt gataacggcg atggcttcga tactgaaaat accaaacaaa aaaatgatca
     8701 tttttcagga atcggcatca gccatgtaga tgagcggata cgcctaatgt atggcgatgc
     8761 atatggctta acgatccaat cagtgattgg gacaggaacg actgtaacga tttgtctacc
     8821 gcttcttcct aaaaatcaat cagaatatca aaaataaaga atagccaagc gctgattttt
     8881 ttattttaag ttaaataaat caatcagtat tcttgacttt catctacgcg tctcttctac
     8941 tgtcagcact ggataacagc ccaatatttg actttctcct ccgagcatct tgatttcttg
     9001 gagcgcattc tctactaatg tcattggacg gtccaacaac aaatcgatca cgaaaaaata
     9061 ttctcccaag ctagttttca atggtcggga ttcaatctta cttaagttga tttcccgcca
     9121 gccaaaagct gccagcattt tatgaagcat ccctggccga ttagcaggta gtgtcaagat
     9181 gacactcatt tttactggag ctgactgctg gctggtcatc tttcggtcac cgacgatcca
     9241 aaaacgtgtc tggttcaact cattatcttg gatattctca gctaagatct ccaatccaac
     9301 atgctgtgct gtttctaatg aagcaatcgc tgctgcgtct tctttcggat gttctgctac
     9361 atacattgct gcagcagttg ttgattctgt tgctactaaa ggaacattag gataatgcgt
     9421 ttctaaaaac tgttgtgatt gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt
     9481 tgttgctgga ttgcctaaaa gctgctgctt gataggaaga acgatttcac ttttaacttc
     9541 gacttctgga tgtttggaaa gaagatcgat tgtgtgatga acagctcctt ccaatgaatt
     9601 ctctacagga acgacagcca gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg
     9661 gatggaagca tacgcagtca attgttctgt aggaaatagc tgacaagccg cctgataagt
     9721 gaatgaactt tctggcccta gatagctgac gttcatatgc ttttgatcct ttctataatg
     9781 gtatcgatga tcttttctgg tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct
     9841 tcataccaag aaagtcgttg tgccaataat gcttttattt cttctcttgt ttttccaaga
     9901 gctaaaggtc gaatagacgt ttcatcttgt tggatacgat caactagaca gtccgcttct
     9961 gcctctaagt aaagaacaat cggctgtgtt tttaaaaaac gccgattttc tgcactttgg
    10021 acaatccctc caccagtcgc gataattttg tcttcatttg acagctttct taaaatatct
    10081 gactccactt ttcgaaagct tttttcaccg taatagtgaa aatattcggc aatcgacaat
    10141 tggatatgtt cctcaatctt tgtatctaaa tctacatact ctttttgtaa acattgagct
    10201 aaccctttac cgattgttgt ttttccagcg cccatgaaac caatcagcaa aatgctagcc
    10261 atgagcttct cctcctgaca caagttctgc taaatcgtca aaaaatgccg gataagagat
    10321 tgaaacagct tcagctcctt ctagttcgca aggtccatca gctatcaaag cagctacttg
    10381 cagcatcata ccgattcgat gatcgcctct gctggacact tttgcgccat gcagaggtgt
    10441 cggcccatgg atgatcagac cgtctgctgt cgcttttatc tttgctccca ttttctgtaa
    10501 ttcttctgcc accgcatcaa ttctgttggt ttcttttact tttaattctt ctgcgtcttt
    10561 gatgatcgtg attccttctg cttgagtagc cactaaagct agaatgggca attcatcaat
    10621 cagacgcgga atgatttctc caccaatcgt tgctttcttc aaatgactcg tcttgacact
    10681 taaatcagcc gattggttct gttcattgtg attcgtctgg gtaatcgctg cgcccatctc
    10741 ctccaacaca tctaagatac cagttcttgt tggattgacc ccgacatttt ttaacaacag
    10801 ttggctttcc ggaacaagaa gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc
    10861 tggaacagtt atctgttgac cagttaattt ttgcggtccg gtcactatga tcgttttatc
    10921 ttccactgtg atccttccgc caaattgacg aatcatttct tccgtatggt tacgggaacg
    10981 ttctttttca acgattacgg atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga
    11041 tttgacttgc gcactggcta caggcatatt gtatcggata ggtgataaag agcgggttcc
    11101 tgtcacagtg attggtagat actggtcatt ttcttctcct tgcaagtcag cgcccatctc
    11161 gcgtaaaggt tccatcactc gccccattgg acgtttagac aacgaagcat ccccgaacag
    11221 agtagtcgta aaaggctgtc cagccaaaat acccatcaat aaacgtatgg tcgtaccgga
    11281 gtttcccatg tcaattgatt cggttggttg gacaaatgag tggctaccgc gaccatgaat
    11341 cttgatcacc tcttcctctt cttcgatctc gacacctaat tgttggaagg catgtaaagt
    11401 actcagacaa tcttctgcgc gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc
    11461 tccaaacatg atgctgcgat gggaaattga tttatctgct ggtatcctaa cagtccctct
    11521 taatccatgt atttgttgta ataattgcat ttatccagcc tcctatttga tccagcaatg
    11581 ataactggta ttagacataa tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa
    11641 actgatttgc agtattccta aaatatcttc cctggtctct tggatcttca aattaatcaa
    11701 agaaactccc gcttttccga tcagtccagt tacttctgca ataacgccag gttcatctgg
    11761 cacatcgata aataaatcaa aaaaggcagg aatcgcgcct tgcttatgga caggcaactg
    11821 gtctcgactt tcttttgccc gattgaaaaa agaaaagatt tccgattggt tctcagtcat
    11881 gatccattct gctatttgtg tcatttcttg ttgccaatct gccaatcgtt ccaataatat
    11941 ctgcttattg ctcaacaaaa tatctgtcca catgacagga tctgaggaag cgatcctagt
    12001 gatatctcga aagcctcctg ctgccagttg tttggctcgc ggatactctt gattgaattg
    12061 ttctgcctga ttgactaagc cagctgccag aatatgtgga aaatgactta gcattcctgt
    12121 tatacggtca tgttctcttg ctgtaagagt tacatatttt gctttggttc cgcaaaatag
    12181 ttcttgcagt ttttcaacat cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc
    12241 attttcaaat agtttagcat ctgctgcctg tatacctgat ttatgagaac cagccattgg
    12301 atgtccaccg acaaaccgaa gatttttctg ctcagcggat gtcacgactt gctgcttcgt
    12361 actgctgaca tccgtaatga tgacgtgatc agacaagttg attctttcaa ggacatcaag
    12421 ataagctaag gttgtacgga cgggaacggc taataagata acgtctgctt gttctgcacc
    12481 tgtttcaaaa tcacttgcaa cgtaatcaac gatctgctgt tctactgctt gctcacgggt
    12541 ttttgactga ctatcccaac caactactat cagttctgga ttggtctgac gaatacaaag
    12601 tgccatagaa gcaccaatca gtccaagccc cacgataaaa acatgttgtg ccatcttatt
    12661 tgcccccttt ttagtaatgt ttcaagtagt cacggtactc cttcactgca gctttcaact
    12721 caacaagcga atcacttggg aattttgaca atagctctgt cgctaccaca gtggctacaa
    12781 cattttccgc aacgacgcta gctgcaggaa ctgctgtact atccgaacgt tctacacttg
    12841 ctttgtaagg ttcttttgta tcgatatcaa cactttgaag tggcttgtac aatgtaggaa
    12901 tgggtttcat gaccccgcga atgacaagtg gttcgccatt ggtcattccg ccttcgaagc
    12961 cgcctagatt attggtacgt cggaaatagc ctctttcttc ttcccatagg atctcatcca
    13021 tcacttctga gcctggtaat gaaccagaag tgaatccgac cccaaattct acgcctttaa
    13081 aggcattgat actaaccaca gcttgtgcga ttttggcatc tagcttcgtg tcccattgta
    13141 cgtagcttcc taatccagct ggaacgcctc caacgagcac ttctacaatt cctccgatcg
    13201 tatctccatt tttctttgtc tgatcgatca aatcttttat tctttgctca actgctggat
    13261 caacaactcg tacttctgac gcttcagaaa tttctttgat ttcttgaatc gagatatttc
    13321 caggtatttc tgcttggatt ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa
    13381 gttcttccag aattttcttg gcaattgcgc cgattgctac acgcatggtc gtctctcttg
    13441 cagaggaccg ttcaagcaca ttccgaagat ctcgatgatg gtatttcata ccgcctacca
    13501 aatccgcgtg tcctggacgc ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca
    13561 cttctgctac agacatgaca gttgtccaat ttttccaatc tttattttct accactaaag
    13621 tgacaggtga accaattgtt ttgccgtgac ggatgccaga cgtgatccga acacgatctt
    13681 tttcgatctt catccttcct cctctgccgt aaccagcttg tctgcgagcg agttcgtgat
    13741 tgatttcttc ttctgacaga ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt
    13801 ctggtccatg ggattctccc gcagtcatat aacgcatctt acagtcctcc taagtaatct
    13861 ttgaatgtct ctgtgggaac aggaacgatt tttgcttgcc caatcttttc tagcaagatg
    13921 atattcaatt ggcttcctct tgctttctta tcatgggtta tcgcgtggaa taattcatct
    13981 ggatgactta gatcgtacgt aatcggcaga tggaattttt gaagtatcct ttctaaagca
    14041 gctgtcgatc cagttggaga caagccgatt ttttctgcat gagaagtgat ggctaccatt
    14101 ccaatagcta ctccttctcc atgactgact accccatatc ctgctgtatt ttcaattgca
    14161 tggccaattg tatgaccaaa atttaaaata agtcgatttc cttggtcaaa gacatcttct
    14221 tccactactt ttcgtttgat ttccaacgta gcagtaatga ttggaacagc atgttccaga
    14281 agatcttttt cgtctttcag ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct
    14341 gctgatttga tgatttcagc gattccttct cgtaaacgac gtaccggcaa agtttttaga
    14401 acctcaggat caatcaatac accagctggc tggctaaatg ttccgacaag gtttttcgct
    14461 ttgtttgtat tgactgctgt cttcccgcca atactagaat ctacttgtgc aagtagcgta
    14521 gtcggaattt gaacgaaatg gatcccacgc atgaacgtcg aggccacgaa tgctgctaga
    14581 tcacccacca ttcctccacc aagtgcaagt atcccatcgc tgcgggtaaa atcattatct
    14641 gctaaaaaat cgtataactc agctgcttgt tctaaagatt tactggtctc acccgccggt
    14701 acgattgaaa ggactggttc aaaattagct tgtctcaatt ggaacatgat tttttctgca
    14761 tatagtggag caacgtttgt atcagtgatc acagctactt tttgaggtct ccaaatcgtt
    14821 tgaagccatg atccagcctg ttctagtgcg cctttttcaa tatgaatatc gtatttttgg
    14881 ttatcaacat gtacagtaag cattcgtttc acttctttct tttaaaaagc tggaattaat
    14941 cgagtgtctg aatcttttcc attgcttctt tcatgatcgc aacttctttc atcatgcgtg
    15001 agtaagtctt ttcattcaac gattggggac cgtctgacca agcatttgca ggatcaggat
    15061 ggatctctac gatcatgcca tctgctccgc ttgccacacc cgcacgagcc attggtggta
    15121 caagttccca aattcctgta ccatgacttg gatcaacaat cacagggaaa tgagttaatt
    15181 ttttcatcaa tgggacagca cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc
    15241 gaatcccacg ttcgataaaa atgacaggag atttgtcttc gactgcaatg tattctgcag
    15301 cattaagcca ttcattgatc gtaccggaaa ttccacgttt caatccaaca ggtttacctg
    15361 ttttaccgac agcagatagc agtttaaaat tttgcatatt acgtgcgcca atctgtagga
    15421 tatcgctgta ctcagccacc atatcgatat gcccttcatc catcacttca gtaatcactt
    15481 tcattccaaa ttcatcagcc gcttgacgga tgtatttcaa tccttcttct tctaaacctt
    15541 ggaaagcata tggagaagta cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc
    15601 cggctttggc cattcgcgca cattctctga tttggtctaa tccttcgata gaacaaggac
    15661 cagccatcgt cacgaaactg ccgtcaccaa tttttactcc gtctacatcc acgactgtat
    15721 tgccaggatg gaattctcga gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt
    15781 ctactccttc atagcgtgta aatgctcctt cttgtaaact tcgcgtatca ccttttagtc
    15841 caatcactac tcgttctgtt ccttgatcga ttgagacttt gaatccttct ttttcgatat
    15901 gatcgacgac tttttttatt tgttcttccg ttgcttcttt tttcataatt actatcattg
    15961 tttttcccgc tttcttttgt ttacttatct atcttggctg attttctcta ctttttcaag
    16021 gtggttttac attaattcct actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt
    16081 ctttcctact tatgacccag ataatcaaca aaaaaagatg tccctgtagg aaattgcctc
    16141 tacagtgaac atcttcaacg agccttaaaa agcgctgcaa aaatataaaa tagccactat
    16201 agatgaattt ctctacgtgg ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac
    16261 aaacctggtt tgtttgtacc cacgaagtca tgaatacaaa cctatctaaa atagctaaag
    16321 taatacgtat tcagttttgt aagttttcta gatttcataa aaaatcgctc caaactgatg
    16381 taagaattgt acctagtata gacataaaaa aatcgactgt caatcatttt tatgaaactt
    16441 tttttaattt tctgatagtt aactttgttt ttcagaaaaa taacaattgg ttttattgaa
    16501 gaaaatagtc atgaacaaaa gtatctgaga acttttttac tctcttgttc atgacatata
    16561 gaataaagca gctttgtctt gtaaactccg tttttcaaat aataatctaa agattgctac
    16621 tgaataataa agccgatttc atggtcctct tcgctgctga ttcggtaagg tgactcaaca
    16681 tccgctcccc agctattgat acccccgact cctcttactt ttgcaaaaat cgtaagaacc
    16741 gttcgtcttt ctggcggtag ttcttctata tgtgttgcct gttccagttc ttctgctttg
    16801 aatggtaaag cggaaaaagc aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct
    16861 tcttgatctt tatccgtatt atccaacgtt tgatttcttg ttagttctac ccatttcgtt
    16921 tccatatgca tgccgcattc ttggggaaca aggtatgggg aaacggggag tcctgccact
    16981 ttataaatac cttcgacacc accagccatc cgatccggat atgtttcccc tgataggcct
    17041 tcatactcaa aaaattttgc tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat
    17101 tccggtaatc ctttttgtcc ataataatgc atattgacaa gcattttacc ctctccagcg
    17161 atttggtagg aaattgtcac ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg
    17221 atttcaaccg tttcagcgta ttcattactt gaatattgat tatttactgg agcaatcggc
    17281 aaatcgatct ttttattgtc caccagtact tctatttctt tgacttttgg atacaatccg
    17341 gctcctaacc acataccgga tttaaatcca aatccgctac ctctgtcatt atcggtcgtt
    17401 gctcgccaaa aaactggaag tgtttcccgg tatagccatt cttttccgtt tttattgagc
    17461 gattccagtc cgcctcttgt ataagaaaaa atataatgcg tattccccga tttgacacct
    17521 aatgtacagt cgccgaagac gattgcaact ttttccgtat ccatatgact tttatttact
    17581 gtatttttca taataatatc ttacctcctg catggcgggt ttttcttgtc catctgcaaa
    17641 aacgatccca ttccctgaga attcatagtc acttggttta tcgtcaaagt caccgccata
    17701 gcgcatcact tctctgcctg tgattggatc agtcacttgg atcgcctgat ctttaaaatc
    17761 ccatatatag cctccttggt acatttcata acgatcaagc aacgtcatgt aagaatccat
    17821 tccacctaac gaattcccca tgtcatgcat atattcacat aagatgaacg gtttttccgc
    17881 tttattttca aggtagtcaa tgatctcttc tggtggcgca tacatgcagc tttttacatc
    17941 tgaaatcgaa tcttcgaatg ctggatttgg aaaattccct tcataatgga caagtcgatc
    18001 ggggtctact tttttgaagt aatcgttcat ttgtcgaatg ttttcttccg cataagattc
    18061 atttccaaga gaccaaaaaa gaatacttgg atggtttttt aatgtttcga aattcgtttt
    18121 tgctcgatca agaacagccg cctgccactg aggtactgca cctggtacgt tgtaagaagg
    18181 ctcaaatgcg cccatttttt gccatgagcc atgggattcg aggttcgttt ccgccatcac
    18241 atggattcct gcttggtcgc ataaataata ccaagtgatc tggttggggt aatgagatgt
    18301 ccgtacgccg ttgatctttg cattttttat gatagccaaa tctttttcca tatcttctat
    18361 agtgatggcg cgtccttttt tcggatgcca ctcatgtcga tttaccccgt tgataatcat
    18421 ccgttttcca ttgaagtaga tgattttatc tttgatttcg attttacgaa aaccgaagga
    18481 atagtcaata tactccgtta ctcttttttc ttcgtctatc gtctccaatt caagcttata
    18541 taaattgggc tgaaaatgcc cccacagtgc cacattttca aatccatcga tgcgaatcgt
    18601 catttgctct tttaacggat attgctgttg atagatttcc ttcccatcag gatctagtat
    18661 cgctacattc agctgactgt ttttggctac ttgctcaaaa gacaaatcta cttcaagttt
    18721 gccattttga catttgtcat ctaagcgagg tttgatccaa agatcttcta aatggttttg
    18781 tcctcgagca actaagaaga catctctgaa gatcccaaaa aatcggaaaa agtcctgatc
    18841 ttccaagaat gcagctgtac ttcttttgta aacctccaca gctagaatat tttcttcttc
    18901 caaataaggt gttaaatcaa attcagacgg agtgaacgaa tcttcggcat acccgataaa
    18961 atgaccattc aaccaaataa acattgcttg ttctacacca gcaaaatgaa tcgagatttg
    19021 ttttcccttt agaccttctt ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc
    19081 tttagcagct gaaaagatcc cttccgcctc tttctcaggg cttgtcgtga aagggggacg
    19141 gcgaaataca tgtccctccc acggatacat cgtattgatg taatggatct tgtcataatt
    19201 tgctaattca atatgactag gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt
    19261 tttataaaat gtttttggtc gtaccgaagg atttggcgaa taacaaaaac gccatgatcc
    19321 atttaaagac tgtttaaggg aggatgtggt ttctacttct tcccttgttg cataacaaac
    19381 atgatcgcta tgtgcatttg attggttcac tctaaaaact tgtggatcat ctaaccattt
    19441 tatatttgct ttcatacttt tttccttctc tctcataact ttttgaaatg aagcagttct
    19501 gtttggaaat caccttgaaa atcggggaag taaagtccaa ctgtcatcaa ttcggccccc
    19561 gaaaatatcc gcttcgaggt ctgttcctga taaagtgcct catcatctaa ccccatcaga
    19621 tatacttcat ggaacgctgg ttgagctgaa gctagtatcc tccctaaaaa cacaatagct
    19681 tcatcttgtt taggagacac aaacatccat gcggcaatat tttcttcaaa aggactcgcc
    19741 aaacgataat aatggccata ctggatcacc ggacgaatcg tttgatagga tataatttgg
    19801 tcttttactt gctttttttc ttcaggagac agctttgtca aatccagttc ataaccaaaa
    19861 acagcgctca tagctgtttc tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga
    19921 tttggtacag ctgatacatg agctgtgatg gacgaaatcg gataagcaag gcttgttcca
    19981 tattggattt tcatacgctc cactgcatcc gtgttatcac ttgtccatga ctgcggcata
    20041 taataaataa acccggcatc aaaccgtcca cctccaccag aacagccttc ccataagatt
    20101 tccggataat cagttgtcaa atgttcaagt agttcataaa gcccgagcat ataacgatgc
    20161 gctacttctc cttgtctctg tgggtcaagg gtaatcgaat agacatctga aagcgaacgg
    20221 ttcatatccc atttgatgta gtcaagagga atcgtatcta aaatctttct catttgtttc
    20281 tcaatcgtct gccgaacatc taaccttgta aaatccagta catgttgtga tctggaagca
    20341 gaaggcattc tacctggctc ctgcataaga aaatcaggat gtgttcgata cagttcagaa
    20401 tcaaccgaga tcatttcagg ttcaaaccat aaaccaaatt tcaatccttt gctatgagca
    20461 taatctgcta tttcacgtaa tccatttgtc aacttgcctt catactcgaa ccagtctcct
    20521 aatgaagaat tgtccgcatc tctttttcca aaccagccat catctaatac gaacatttcg
    20581 atgcctagct cctttgcttc atcaatgatc gccttgattt tttcactatt gaagtcaaag
    20641 taagtggctt cccagttatt gaccagaatc ggccgttcag caaattgatg acgacctctt
    20701 gcgattcttt cacgtagcaa ctcatggtgg atctgactca ttttgttcaa tccctgactt
    20761 gagtaagaaa ggatcatttc aggtgtttga aaagactggc ctgcattcaa ttcccacgaa
    20821 aaacgatggc tgttgatccc accgacgact ctcaattgat tgatctgatc tttttcaagt
    20881 tcgaaagaat ggttgccgga ataaacaaat tgaagtccga tcgcttctcc agtattttct
    20941 gtcgtatgat gatgaactaa agcaataaag ttattcatat ggtgactgct cgttcctcga
    21001 cggctttcaa atacttttgt tccagataaa acagattgcc gtgaaatctg tctttcattg
    21061 acatgtgctc ctggcaaagc aatgacttca tcaaatcgcc tagtatgggc aaagtctagc
    21121 tggaaactag ccgctttttc tagtttgatt gtttctccgg tttcatttct tatctttaca
    21181 gatcgtgtga tcactgctct atcagtaaat atggtataga acaaatcgaa ataaatcgct
    21241 gtttctctat ccttaagtga aatcaccaac gtttgtgcct ctgacttgtc catcacataa
    21301 gtttgaggca agccttcgat ctctggcttc ccatctgtaa tataatggct gtcatatctc
    21361 agatccagta agtctgatcc attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc
    21421 atgctgccat gagaagagta ttcttgcggt agtgtatctt tcgacagaga ccggtcagga
    21481 tttaagggaa catttcctga aaatccacga tctcttcggg gataattttt attgtctttg
    21541 tactgcttga ctggtttgcc aaaataaata tgcgccaata cattgctttc ttctatcttt
    21601 atcagataag aaagaaatgt atttcgtaaa tggaagactc ggctcttttc atcaaataag
    21661 atgaaatttt tatctgtttt tctatgcgta atatccatca tttcactccc aacaaaacgg
    21721 aaaccgttta ctttttttta taattcctgt atactgttta ctaaacaatt ttgtcaataa
    21781 aaatttttta tttttttgag gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa
    21841 aggcaaatgt ctctcctgct acagtttccc gtgtgttgaa taacgatcag acgatccatg
    21901 tggctcagac tactcggcaa cggatagtag aggcagctgc tgcgttggat tatgacatca
    21961 gtactcgtaa atatatcaaa aagagaatgc cttcgattgg tgtgatctct acgatcggca
    22021 aagcgagcga agaacaggat atctattaca aacatttgcg agtagggatg gaagaagaag
    22081 ctcgacgtct gcatttaggg atgaatcgaa tctataatct atctgataat cctaaacaat
    22141 gggaagatct agatcagtta ggtgcggtga tcgttgttgg gactgttacg aaagaatcga
    22201 ttaccgcctt gttaaaacaa aacatgcaaa tagtcgtcgt ggataaccct gacatccagc
    22261 aagaggtcga tatggtgtat gcagatcttg aacggatgac taaaaccgta ctggaattgt
    22321 tcttagaaaa tggtcataaa agaatagcct atatcggggg atataaagtc gatatggatg
    22381 aattcggtgg gaagcagatt tctataaatg aaaagaggat gcgtgcctat cagcatttta
    22441 tgatcgatca tcacttagaa aaatatatgt cttatcatct aggtggctgg acagaaaaac
    22501 aaggtgaggt acttgcgact aatctattag aaaatgaatc ccctcttcct actgccattc
    22561 ttgtcgggag cgatccaatg gcaattggtg tctatcgggc attgaaacaa aaaaatatcc
    22621 aaattggaga agagattgtt gtagcaagct ttgataatat cgagacaatc gcaaacctct
    22681 cccctggctt gaccagtgtt caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa
    22741 tggcattgga gcgaattgac ggtatacggg acgaaccaat cattttgact tatcctgcac
    22801 gattgattgt tagggaaagt tttatcccaa gaacaaaaag gtattgaaag agaggttgtg
    22861 aaaagccgct tcgtttcttc atactcaaaa cgaaacggct ttttcacaac ctcttactta
    22921 tacttattca caaaatccaa tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa
    22981 tcaaattggt attcatgggt aatctctttt tttgtatctg tataaaacaa ggattgcacg
    23041 ggtaccttta attctgtcaa ccgattttct aatgcttgac cttgctcctg gaatgagtat
    23101 gcatttccgt cagttatata cgttggcgga aattccttag aaacatggtc agccacacta
    23161 gcttctttca attgctcact cgttttccaa tcttttgttc caatcaacga ccacgcaacg
    23221 gttttgacga aaaacttcat aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa
    23281 tcaacaggtc cgcaataaga aatggttcct ttcagactat cttttggaag tagctgtttg
    23341 attttcattt gtttagcata cgcatcattc gtttgtatag ctgcatattg caatgcgatt
    23401 tgtgaacctg cactatctcc accaaaaaat aattgttcca tgtctagcaa tttgtcgtct
    23461 ttttcttcag ctaataaatc tttgatcagt tcattcactt gaagaacttg attagggtat
    23521 tctgaatcag gcgctaattc ataattcatc gcaaccactg cgatgttggc gtctgaaact
    23581 aattttgtcg caaattcttt gacacccgat ttatctccgc cgacgaatcc tccaccatgt
    23641 acccaaaata gaacaggaac aggccccttg ctgttttttg gatagtagat gtcataagta
    23701 ttctctttat acttggactc atacgtcaaa tctgtttttt tcgccacgtt tttttctgct
    23761 tgatcgaacg tttttttatc agtgatttga acagtatttg aaaacatatg gttgatcaag
    23821 aatgctccag gtctggggga aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga
    23881 atgattccga agaaccatcc gataaattta agaattttct ttttcataag gctccctcag
    23941 tagttagtat taagcattct gattatacca tagtgttatt tcctatcaag ctctcctaga
    24001 tgatttaatg attttcccca aacttcttct gcaatgcttt tgacaaaaga aattttttcc
    24061 attgttcttc aaacaaaaca ttttcttctt ctgttgaagc aaatccacat tgaggactta
    24121 agcacaaacg atccaaaggc agatatcgtg tcgcttcgta gatccggtca atcacttgct
    24181 ggtgctcttc catttcgcca tttttcgtta cagtcaaaat ctaagacaac taatttatct
    24241 tcagagactt tctctaaaag aacaaaactc ccagcacgtt cactatcgta ttctaaataa
    24301 taggcacgga cattttcttg agtaaaataa tgggtctgct acgtcgtcat cccccctgat
    24361 gccgccaaaa tcgaataata atttccgcgt caaacatgta tatttagtgt tgaatcattt
    24421 gagaatatga aaataaaaat ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa
    24481 atctgagaca gaatgacgtt cattctgacc cagatttgat tttgcacaac tcaacagtcc
    24541 ttattggcaa atcgccaaaa taatgtagac taactaaaa
//
LOCUS       DACGLI010000047        23669 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.048, whole genome shotgun sequence.
ACCESSION   DACGLI010000047 DACGLI010000000
VERSION     DACGLI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.048"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            285..692
                     /locus_tag="IXT22_002055"
     CDS             285..692
                     /locus_tag="IXT22_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863391.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            706..1107
                     /locus_tag="IXT22_002056"
     CDS             706..1107
                     /locus_tag="IXT22_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863392.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1109..1480
                     /locus_tag="IXT22_002057"
     CDS             1109..1480
                     /locus_tag="IXT22_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863393.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1516..1818)
                     /locus_tag="IXT22_002058"
     CDS             complement(1516..1818)
                     /locus_tag="IXT22_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863394.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2067..2267)
                     /locus_tag="IXT22_002059"
     CDS             complement(2067..2267)
                     /locus_tag="IXT22_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4863395.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(2572..3804)
                     /locus_tag="IXT22_002060"
     CDS             complement(2572..3804)
                     /locus_tag="IXT22_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4863396.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4059..4628
                     /locus_tag="IXT22_002061"
     CDS             4059..4628
                     /locus_tag="IXT22_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4863397.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(4806..5246)
                     /locus_tag="IXT22_002062"
     CDS             complement(4806..5246)
                     /locus_tag="IXT22_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAQ4863398.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5404..6168
                     /gene="map"
                     /locus_tag="IXT22_002063"
     CDS             5404..6168
                     /gene="map"
                     /locus_tag="IXT22_002063"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAQ4863399.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6200..7123
                     /locus_tag="IXT22_002064"
     CDS             6200..7123
                     /locus_tag="IXT22_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAQ4863400.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7199..8338
                     /locus_tag="IXT22_002065"
     CDS             7199..8338
                     /locus_tag="IXT22_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAQ4863401.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8331..9131
                     /locus_tag="IXT22_002066"
     CDS             8331..9131
                     /locus_tag="IXT22_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863402.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9131..9958
                     /locus_tag="IXT22_002067"
     CDS             9131..9958
                     /locus_tag="IXT22_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863403.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            9936..10670
                     /locus_tag="IXT22_002068"
     CDS             9936..10670
                     /locus_tag="IXT22_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4863404.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            10770..11636
                     /gene="rfbA"
                     /locus_tag="IXT22_002069"
     CDS             10770..11636
                     /gene="rfbA"
                     /locus_tag="IXT22_002069"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAQ4863405.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11650..12222
                     /gene="rfbC"
                     /locus_tag="IXT22_002070"
     CDS             11650..12222
                     /gene="rfbC"
                     /locus_tag="IXT22_002070"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAQ4863406.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12244..13272
                     /gene="rfbB"
                     /locus_tag="IXT22_002071"
     CDS             12244..13272
                     /gene="rfbB"
                     /locus_tag="IXT22_002071"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAQ4863407.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13370..14221
                     /gene="rfbD"
                     /locus_tag="IXT22_002072"
     CDS             13370..14221
                     /gene="rfbD"
                     /locus_tag="IXT22_002072"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAQ4863408.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14256..16289
                     /locus_tag="IXT22_002073"
     CDS             14256..16289
                     /locus_tag="IXT22_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863409.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16333..17613
                     /locus_tag="IXT22_002074"
     CDS             16333..17613
                     /locus_tag="IXT22_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAQ4863410.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            17823..18629
                     /locus_tag="IXT22_002075"
     CDS             17823..18629
                     /locus_tag="IXT22_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4863411.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18641..19861
                     /locus_tag="IXT22_002076"
     CDS             18641..19861
                     /locus_tag="IXT22_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863412.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            19851..21437
                     /locus_tag="IXT22_002077"
     CDS             19851..21437
                     /locus_tag="IXT22_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4863413.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21476..23614
                     /locus_tag="IXT22_002078"
     CDS             21476..23614
                     /locus_tag="IXT22_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4863414.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
BASE COUNT         7569 a         3940 c         4852 g         7308 t
ORIGIN      
        1 aggggaagta catatagttg ttgatatagt tgctaatatt gttagctaat ttgttagtaa
       61 aactgtatac gaatttagat agtaaaaaaa cagtttgttc cttatataga ggcactttta
      121 ctactgatta aatgtcagat atgcttacaa atatacttat aaatatgctt acaaaattag
      181 ctaatatttc cgttgacaaa gctttgttac tattgttaaa ctaaattgac tagcaaaagt
      241 gaaacataaa tttattaaat aaatgtaaaa attaggagaa atcaatgtct tatagagtac
      301 aattaataat ttcagaagat gtagaaagtc agcaatttgg cactaatgtt attaataaag
      361 taattaatcc agctctttct attaatgcgc ctttaattcc tactgcttta tcattttctg
      421 taacagctgt ggtgtctgag atagaggata cagaaaagat aaaaatagta gaaattgaag
      481 ttttaaacaa gaatgaaaaa caaatttttt ctacgggtga agtatcggta agcttgcctc
      541 ctcaagttaa cgatataaac tttaatataa acgccagaaa tgtcttggtt gaagaagcag
      601 gagagcatta tgctgttgtt aaatttaatg gaactgagat tggaaggcaa atctttgata
      661 tcaaggtcaa caaaccagtg gaaaaaaatt aaggagacga tacggatgct tgatatagta
      721 ccatcaaata cacatcggag tggtagctta ataaattttg ctgcgatttt tgcttgcgca
      781 tcggtaattc tagcatctcc agttgttgtg gatgcaagtt ctactccgaa aactaaaaat
      841 gataatcaac ttgtaattac tacaaaaaat gagattaaca caatttcaag taatgatggc
      901 aaaatttttg atgtgataaa tacggtttta aaaagaaaag ctgaaatcaa tataaaatat
      961 gatgaagatt taaacttgta tttctttgtt atcaaaacaa catctgaatt gttttcctca
     1021 gattacgatg ttttggatac tctcgataat gtattatctg actataaata tatggggaaa
     1081 tctgtagtag caactttggg ggaataaaat gtttgacttt aatgaatatt tatctatttc
     1141 caaacaaatt gaatcagatg ataaatataa ttctaaagaa tcttatagaa gaactgctgt
     1201 ttcaagagca tactacagtg cttttaaaaa atctgatgag tatttgaaag aaaattatga
     1261 tattatttat aatggaagta gcggaaaagg aagccaccaa accgtttgga atttgttttc
     1321 aacagttaag gaattgaata ccttaggaat acataatagt gggtatagaa tgttagagaa
     1381 aagaaaatgt gctgactata ttcctaatga aaccattacg aaaacagata tggcgctgat
     1441 gaatcgagaa gcagaaaaaa taataaacaa actcacctaa tgaatttcaa gcgagtttgt
     1501 ttgttatttt tttatttaat ctttgtatct ttctggatca acgaaagtat actttatata
     1561 gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca gtcacgatat caaacaaaaa
     1621 gtatacaccc ttcttcattc tagttttcgc agcaggaatt ttgaaatagt tcttattaga
     1681 atagtagaga ttgattaata agctatcttc gattgctaaa aagaaaactt ctgaattcca
     1741 tactttataa aaatctttga taaatctatt cgaagggtca aatttaaacc ataattgtgt
     1801 ttttccttcc atcagcataa aagttcacct caaaaagagt atacgaacga atgttctttt
     1861 tgtgaaggcg gaatttaata tactgaataa tagaaaacaa gtacttgtgc caaattatgt
     1921 gccaaaaaaa ttcgaattca acaaaatgta aacaaataga aaaccttcta tattaagatt
     1981 tcctgcaata acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac
     2041 ccctgtatcc tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa
     2101 ctgctatgtc ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata
     2161 gatgcatgcg tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg
     2221 attactaaag aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt
     2281 cgaattaaac gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct
     2341 taactctagc ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga
     2401 ctttttatta tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt
     2461 accatataaa aaaacggtgg ggttgtttag cgaaataaag gatctaagcc aatagcttag
     2521 atcctttatt ctatgcttta tattattttt tgcatgtgtg cgaaagtata ctcaagccca
     2581 atcgccattt cggaaaatcg gtactgtaga gccatcttca cggattccgt cgatatccat
     2641 cttgtcagat cctaccatga aatctacgtg ggtttgactt ctattcaatc cagcttctgc
     2701 taattcttca tcggacattt ctgtaccgcc tttcacactg aaggcataag cagaacctag
     2761 tgctaagtga ttcgatgcgt tttcatcaaa taatgtattg aaaaagatga tgccagattg
     2821 agaaataggt gaagggtcag gtacaagtgc gacttctcct aaacgacgcg caccttcatc
     2881 tgtatcaagc agttttgcta agacatcttc tccttgttcg gcagaaaaat caacaacttt
     2941 tccatcttta aaagtaaatt tcatacccga gatgatggtg ccagcataac tcagtggctt
     3001 tgtacttgaa atgtaaccat ctactcgatg actgtcaggt gctgtgaaca cttcttccgt
     3061 cggcatattt gccatgaatt tttctccacg agcattatag cttccagcgc cttcccaaag
     3121 atggttttta ggcaatccga taatgatatc tgtaccggga gcagtatagt gaagggcaga
     3181 aaattgttct cgattcaatt cttctgcttt ttttgctaat ttttcatcat gcttcttcca
     3241 tgctaagaca gggtcttctt catagacacg agtcgttttg aaaatctgat cccataatgc
     3301 ctcaacttgt ttttcttctg gcagttctgg gaagactttt gctgcccatt gtttaccagc
     3361 cgcagccacg acagtccaac tgactttatt tgcttgagtt gccttgcgta aattcattag
     3421 tgctttgcca ttcgctgatt gataagacgc tactcgatgg ctatctacac cagcaaatgc
     3481 atcgggatcg gcagaaacaa cgctgatcct gcttgctcct ttttcaagcc attcatccgc
     3541 ttgatcgatt ttagattgtg gtacattctc aatacgatcc gttgcagcat gtaaaagaaa
     3601 ttctctttgg atctggtcgt cagtccattg aacgataacc tcagcggctc ctagtttata
     3661 agcttcttgt gtgatcaatc gagcaagggg tgcctgttcc acgctgatct gtaaaacaac
     3721 tgtgtgtcct ttttctgtgg ctacgccagt ttctgcaatt aagcgtgcat atttttttag
     3781 aagttcatta aaatcagata acataataaa aattcctcct caccattttt tctggtaact
     3841 attagcatga taccatttaa ttatgattca aacaatgagg ctttaaataa aaaaaggagg
     3901 ttattttttt aaggttaagt ttcatgatat atgttactac ttgctatttc agcttgtgaa
     3961 gaaaatcaaa aactaatttt gcatatcaaa aaaaacatgt tacaatgaaa ttaatcaatg
     4021 gtggaagcgt tataaaaaaa ttaaggagat taaaaaatat ggcaagaaaa aagacgatta
     4081 ctagagaaca gattttggca gctgcttatg aagtagctgc caccgatgga tttacacgat
     4141 ttactgcgag aaacatcgcg aacaaaatga attgttccac gcaaccgatt tatcttgagt
     4201 ttaaaaatat ggatgacttg agacaagctc tttttgagca gatctatgat catttacaat
     4261 atgaagtgtt cactgttgag catacaggga atacgattat cgatcttgct tttaattata
     4321 tccattttgc aagaagagag aagaagttgt atcgttcact gtacttagaa gaatatggtg
     4381 gaggaaaaga gatgcagaat ttctcttata cttactttgt gaatacagtg aaacgcgatc
     4441 cagcttatgt gaatctttca gaagagcaga tcgaatcttt gtataatggg acatggatca
     4501 tagctactgg gatcgcagct ttgatgtctt caagcatcat ccatccaact gatgaacaga
     4561 ttgaaaagat gatccaagac agtatagatg ctatcttgaa attcaaagaa ccaatcgaaa
     4621 tcgattgaat atactcaaaa gttccacaaa tcagtaggta acaagagatg tgtcaaaata
     4681 aggaaaagtt cgtttttctt acagcgtatg catttttaac tcccgaagaa ctcttccatg
     4741 aatgcaatga ataaaagagc catacagatt gaataaatct ggatggctct tttattgcaa
     4801 gtatattaaa tttttgcgac tagttcttta gcgaaagctt ctaaattttc gatatcttct
     4861 tcttcagcat tcagatccac tttaacattt tcggctcctt ttgatgcgcc tgtttttgca
     4921 aaagcagcat cgaaatcatc caccgatttg cagaattcat cgtaaaaagt atcaccagat
     4981 ccgcagacac cgtaaatttt tcccaataga tccaattctt gcaagtcttc ataaaagtct
     5041 acgatctcat caggcagatc gccatcatcg tatgtataag tagctactac gcaaatatct
     5101 gcctcctcga attcatctgc atctacttgg gtacattcgt tgatttcgac ttcgatatcc
     5161 agattttcaa atgcttctgc aacaatatcg gcgatttctt cagtgtttcc tgtcatgcta
     5221 gcatatacga tttttgctaa agccatgatg tgcctcctcg tttataatta tttaacaatt
     5281 atgaattata ccaaaacatc attgaaaaga aaataaaacc taaagacacc tggggaatgt
     5341 catttggcta aatgtatgcc gctatgttaa aatgagaggg atttgtaaaa aggagacgaa
     5401 aatatgatta ctttaaaatc agcacgtgaa attgaaatga tggcagaatc tggagcttta
     5461 ttagcagatg tacataaaaa tctgcgtgat tttataaaac caggaatcac aagttgggat
     5521 attgaggtat ttgtcagaaa ctatatcgag agtcatggcg gaattgctgc gcaaattggc
     5581 tttgaagggt atgaatatgc gacttgtatc agtataaatg atgaaatttg tcatggattc
     5641 cctcgtaaaa agcctttgaa aaacggtgat ttggtaaaag tcgatatgtg tatcgatttg
     5701 aaaggcggca tttctgattc ttgttgggcc tatgtagttg gagaatctac acctgagatc
     5761 gaccgattga tggaagtaac gaagaaagct ttgtacatcg gtattgagca agcacaagta
     5821 gggaatcgga ttggtgacat cggtcatgct atccaaactt atgtagaagg cgaaaatcta
     5881 gcgatcgttc gtgattttat tggtcatggc gttggtccta cgattcatga agaaccagca
     5941 gttcctcatt acggagaagc tggaaaaggg ttgcggttga aagaaggcat ggttatcacg
     6001 atcgaaccta tggttaatac cggaacttgg aaaatgaaaa tggatcctaa cggctggact
     6061 gcgtatacaa gagacggcgg actttcttgc caatatgaac atacattggc tattactaaa
     6121 gatggtccaa gaattttgac atcacaagga gaagaaggca cttattgatc tatccagtca
     6181 ataggtacgg gagaggtaca tgaaagtttg gaacaaaata aaacaaaatg aaaatctgat
     6241 gcgctttatt gagacgactc aaaagcgcat cactgattca gaaatgagta cgacctctgt
     6301 cgtcgttgct tattatttac tcttgtcttt atttccattg attattgctt ttggtaatat
     6361 tttaccgttt ctccacatcg atcaagagac tgtactgacc tatttacgag aagtgattcc
     6421 tgagaccgtt taccagttta tcggtcctgc aatcaaagac cttttgacac aaagttcagg
     6481 aggcttgtta tccgtttctg cattagcggc tttatggtct gcaagtcaaa gtatcaatgc
     6541 tttgcaaatt gcgatgaata aagcgtatgg cgtagaaaat agaaaaaatt ttttgatcgt
     6601 ccgtttcttc tcactaattg tcattgtctt gttcatgatt gctattagtg gggtaactat
     6661 cgttcttggg ttgggacagc tgattttgga tgctattcag ccaatcgtac aaatacccgt
     6721 gaactttatc gatcagttcc aaactttgaa gtggccaatc acattggtag ctttatttgt
     6781 catcatgttc ttgatttatt taattgtccc taatgctcag ttgaagttga agacgatcat
     6841 tccgggcacg atcttcgcta ctgtcggctg gatgctgtta tcacaagtgt ttagtatcta
     6901 tgctaggtat tttgcaacga ggatcagcgg ttatcagatc ataggaagtt ttattgtact
     6961 catgctttgg cttaattttg ctgctacgat catcattttg ggcggaatca tcaatgcagt
     7021 tgttcaagaa tacgtgacgg gtcatcaaat caaaaaacgt cgagatccaa gccgaaaatg
     7081 gttcaataaa ttgaaaacta aattttctca taaaaaaaag tagaaacaag agttcttatt
     7141 gtaaatttat atcagtaatt tataataatt atgactctta attaaagtag gtgcccatat
     7201 gcttgtttct tttagtatgg ttataagatt ttttctgaca attttattat cactgatatt
     7261 aacacctgta ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac caaatgaaag
     7321 aagaataaat aaagttccaa tgccttcagc gggcggactg cctatcttta tttcatttgt
     7381 tatatcgact ttattcttat tccgtaaaat tatccctcaa tcgtatattg taccgatctt
     7441 gattgcttct ttagtaatca tagtcacagg agtgctcgat gataaatatg agctgacacc
     7501 taaacaaaaa agtataggga tcttgattgc ttctcttatt atttattttg tagcagatat
     7561 acgtattgat tccttcacgc ttccttttat tggatatatc caactaggct ggcttagttt
     7621 tcccgtaacg attttttgga tcttcggtat cacgaatgcg gtcaatctga ttgacggttt
     7681 ggatgggctg gcggcaggga tttcattgat cggtttaatt acgataggaa tcattggata
     7741 ttttttcctc catgcttcta cagtgtatat tccagttgtt attttctgtc ttgtagcaag
     7801 tattatcggt ttttttcctt acaattttta tccggcaaag atttatttag gcgatacagg
     7861 agctctattc ctagggttta tgatggccgt cctttcacta caagggctga agaacgtgac
     7921 ttttgtttca tcgatttctt tgctgatcgt catgggagtg ccggtaacag acacgttttt
     7981 tgctatcatt aggagaaaag caaaccgtgt ttctttttct acagcagata aaaaacatct
     8041 tcatcaccga ctaatcagtt taggctttac tcataaaggt gctgtcctga cgatttatgc
     8101 gatggctttg atgttttctt tcacagctat ggtcatgaat tatactggaa gaatcggaac
     8161 gatcatattg attattgcca tgttgtttgc tgcaatttta ttatttgaat tgattggtct
     8221 gatcaatgag aaacatcagt ttattttaaa aacattgcga tttttaggga ataaagagta
     8281 ccgtacgcaa gtaaaacaga aatatttgaa gaaatggaac cgtcatatag atgaataaca
     8341 aattaaacca gccgatcctt attagtattg tgacggcaaa cagtgataaa atttttcgga
     8401 cactagataa ttttatttca actgtaaaag atgaaacagc agtaaaaatc cgaatttttg
     8461 acaacaattc acttcccgag tacaaaaaaa gactaacaga gtataggaaa tatccctaca
     8521 tcgatatcta ttttcatgat gaaaattccg gatttggtta tggacataat cacaatctga
     8581 tagctagcga ttctcgctat ggcattattt gtaacccaga tattttagtg gatgaagaga
     8641 cagttacagc attggtcttg ttattgaaag aacatccgga atgtgcgatg ttagcaccta
     8701 agattcttaa tgaagatgga acaactcagc acctcatccg tgagcagctg gctgtttttg
     8761 attacgtttt gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac aaacgactgg
     8821 ctgtgtttga atgccgagga ttgcctactg atgctaatag ttatgtacgg atgatctcag
     8881 gtagttttat ggtagctgat attgataaat ttaaagagat aaaggggttt gatgagcgtt
     8941 tcttcatgta ctttgaagac aacgacttgt gtttgagttt tgaaaaagca ggttacaagt
     9001 tattgtacac acccttttat gcagttatcc atttttacgg gaagggtgcg catcgaaatg
     9061 caaaactgtt tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag tgggggtggc
     9121 gttttttctg atgaaaccag aaatattagt agtcgttgtg ctttatcagc aactattcag
     9181 tcaatctcca gcttatggac cattaagcaa agcacttagc gaaaagcaaa ttcagcttat
     9241 tatttacgat aatagtcctc aaaggcagca aaatgagctg tttgaaaaag aaaatatcgt
     9301 ttatcatcat gatccgcaaa atcctggttt agcggtggct tataattttg cgttgtctca
     9361 agcagatgaa ggaacacgtt gtctcgtcac tctggatcag gatacgaggc tagtcgacga
     9421 ttattttgaa ctattgcgta aagtaacctt tacagatgaa tgtgttgctg cagttccgat
     9481 gattttttct gggagccgac aagtttctcc cctatattca gatcgttata tcaatcgtac
     9541 agctcaagca gtagaagttg aaggcccaac agctgaacga atcatggcaa tcaattcagg
     9601 tgttgcctgg tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg ctttttcttt
     9661 agattttttg gatcattggc tgttttggaa agtggatcag ttggaaaaaa ctgtggagat
     9721 ccttcctgta cgaatggaac atgatctttc ggttttagac tatgaaaaag tttcaagtaa
     9781 tcgataccgt tctattttac aagcagaaaa tcgattttat catgaatatg atcaaaggca
     9841 tttatccagt caccgacgac aattattgtt aagaacagct aaacagttct tgaccgtcaa
     9901 aaaccggcat atctggcgga tgactttgcg ctcatatgtt aagaattgga aggtgtgaat
     9961 tcgtgcgttc ggtttgtata gctaccttta atggaggcag atatttaaga gagcagttag
    10021 atagtatttt atctcagctt tcagcagaag atgaagtagt catttctgat gatgggtcag
    10081 tagatgatac atgggatata ttaactgaat acgcagaaaa agataagcga atccagcttt
    10141 tttcggggcc tcgtcaagga ttgatcgcta attttggtta tgcgatccag cagacgaaag
    10201 gagatctaat ctttttggca gaccaagatg atgtttggtt ggagacaaaa gtgaaaaaga
    10261 tcactgacta ttttgagcag aatccggatc agctagtagt agtttctgat ttaatcattg
    10321 tggacagcga gctgcaagag atccatgatt cgtatttttc gtttcgaaat tccaaagaag
    10381 gatggcttaa taatgtgata agaagtcact atattggtgc tggtatggct ttccggtctt
    10441 ctttaaaacc cgatattttg ccgatcccgt cagaagtgcc gatgcatgat atgtggattg
    10501 gtttgctggg aggaaagaag actgggttcc taagagaacc gttaactctg taccgaagac
    10561 atgatttaaa cgcgagtgag attgaaacac attctaaatt acggcaaaaa atttcttggc
    10621 gtgttcatct gattacggcg ttgatcaaac gaaaatggtt taaacgttga taaaagatgt
    10681 ttaaatcctt aatatttcca tgacaaatat aacaattgat gagataataa caaagtgaaa
    10741 tttgaaatca aaaaggagag cagatatcca tgaagggaat cattcttgct gggggcagcg
    10801 gaacacgtct gtacccttta acaaaggcaa catcgaaaca attgatgccg atttatgaca
    10861 aaccaatgat ttattatcca atgtctactc tgatgttggc gggaatcaaa gaaattctga
    10921 ttatttcaac gccacaagat acaccacgtt tcaaggaatt atttggaaac ggaaatgatt
    10981 taggactgca gatcgaatat gcagtacaag aaagtccaga tggattggca caagcgttta
    11041 tcattggaga agaatttatt ggagatgata gtgtctgctt ggtattaggg gacaatattt
    11101 actatggtgg cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat acaggcgcga
    11161 cagtatttgg ctatcatgtc aatgatccag aacgctttgg tgtagtagaa tttgatgaga
    11221 atatgcaagc tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat tacgctgtaa
    11281 ctggccttta tttttatgac aatgaggtaa tttctatcgc taaaggtatc aaaccttcag
    11341 aacgtggaga actagagatt acggatgtca ataaagcata tttggataaa ggaaaactat
    11401 ccgtagaact tatgggacgc ggatttgctt ggcttgatac aggaacacat gaatcattgc
    11461 ttgaagcatc tacctttatc gaaacaattg aaaaacgtca gaacttaaaa gtggcttgtt
    11521 tggaagaaat tgcttaccgt atgggctaca tcgataagga acaattgctg gcccttgcac
    11581 agccattgaa aaaaaatcaa tacggtcaat atttattgaa tttggccgct gaataaggag
    11641 tccttacaga tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt agaaatggac
    11701 gtctttggcg atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa atttgcagaa
    11761 catggattga aatatgactt tgttcaagac aaccattcac tatcagctga agctggtgtc
    11821 cttcgggggc ttcatttcca aaaaggagaa gctgcacaga caaaattgat tcgggtagtc
    11881 actggagcag ttttagatgt agtagtggat atccgcaaag gtagcccgac ttatggtcaa
    11941 tgggacggat ttatcttatc tgaacataat catcgacagt tgcttgtacc taaaggatat
    12001 gcccatggat tcgttacttt gacaccaaat gtgaacttcc tttataagtg tgataattac
    12061 tataatgcag aagcagatgg gggcatcgca tttgatgatc cagatttagc gattgattgg
    12121 ccaattgatc catcaagagc gattatgtcg gaaaaagatc accgtcatcc gacattaaaa
    12181 gaatttgaag cagaaaatcc atttgtttac ggagaaatct aagaattaag gagaaatttt
    12241 cttatgaaaa acatcattgt taccggaggt gccggattca tcggctctaa tttcgttcat
    12301 tacgtggtaa acaatcatcc agaagtgcat gtcactgttt tggataaact gacttatgca
    12361 ggaaacaaag agaacttggc cggacttcct agcgatcgcg tagaattggt cgtaggagat
    12421 gttgcagatg cagaattagt ggaccgtcta gtaaaagaag cggacgcagt tgttcattac
    12481 gcggcagaat cccataacga taattcatta aaagatcctt tcccatttgt acaaacgaat
    12541 atcattggta cgtatacact tttagaagct tgccgcaagt atgatgtacg ctatcatcac
    12601 gtatctactg acgaggttta cggcgatctt ccattacgtg aagacctgcc aggacatggg
    12661 gaaggcgaag gagaaaaatt cactgcggaa acaccatata atccttcaag tccatattct
    12721 tctacaaaag ctggttcaga tctgttagta aaagcatggg tgcgttcttt tggcttacgt
    12781 gcaaccattt caaactgttc aaacaactat ggtccttatc agcatattga aaaatttatt
    12841 cctcgccaag taacgagtat cttaagcggt attcgtccaa aattatatgg cgaaggaaag
    12901 aatgttcgtg actggatcca tacgaatgat cattcttcag cagtgtggct gattttgacg
    12961 aaaggcagaa ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga taataagacc
    13021 gtgatggaat tgatcttaga aatgatgggc caaccaaaag acgcatacga ccatgtaaac
    13081 gaccgcgcag ggcacgattt gcgttatgca atcgattcga caaaattgcg agaagagcta
    13141 ggttggcagc ctgagtttac gaacttccgt gatgggttgg ctgacacgat caaatggtac
    13201 gaagaacatg aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc atatgccaaa
    13261 aatggacaat aatacagagg aaatttcact gtattaatgg aaaaacacat gtgaggcagg
    13321 cgctcgcctg tctctttttt aaaataaaaa tcaaggagcg gataaccata tgtttttatt
    13381 aactggagga aatggacaat taggtacaga attgcgccat ttattagatg aaaaaaatct
    13441 gccatatgtt tcaacagatg caaaagactt ggatatcaca gatgctgaga aaacaatggc
    13501 ttatattaca gaattaaaac ccgatgttat tttccattgc gcagcttaca cagcagtaga
    13561 taaagcagaa gaagaagcaa aagaattaga tgagaaaatc aatgtcgatg gcacaagaaa
    13621 tgtagcactt gcagcaaaag ctgtgaatgc acaattcgtc tatatcagta cagactatgt
    13681 tttcgatgga aaaaacaaaa atgtagaata cgaagtagac gaccaaacga atccactaaa
    13741 tgaatatggt cgtacgaaat tattaggcga aaaagcagta gaagagattt tagaagacta
    13801 ttatatcata cgaacttctt gggttttcgg gatctatgga cacaatttcg tcttcacgat
    13861 gcaacgccta gcggaaaccc gcgacaaact gactgtagta aatgaccagt ttgggcgacc
    13921 aacttggaca cgtactttgg cagaatttat ggtatatgtc atcgaagaaa aagcaccatt
    13981 tggtatttat catttgtcga acgaaaatag ctgttcttgg tatgagttcg caaaagaaat
    14041 attgaaagat acagatgtag aagttgcacc tgttacgtca gaagaatttc cgcaaaaagc
    14101 aacacgtccg cagtattcag tcatgagcct gaaaaagaca gaagcgttag gttttgtcat
    14161 accaacttgg caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa tgaataagta
    14221 atttcctttt tatcaaatag aatttggagc atgatatgga aaaacaaaca agaagtgcac
    14281 gacgaaaaga aaagccaaaa gcgaatcagg cagattcgaa tttggtgctt gacctgtttc
    14341 taaaactccg ctatcttatt ggcgttttag tcatcgtggt catcgttact tttaatttaa
    14401 acggaagttc acttggtgtt tgggataaat atgtgtcgca aagagacgat gggaaaaaaa
    14461 ctgatgtgat ttttggacag aatcgggaag tgcggtcaga cgaatggctg gtgcagacac
    14521 ctttttacct ctcacaagct gaagaggact tttcgttggt gaacgaggat tattcattaa
    14581 acggacaaaa catgatcatt gcgtataatt ctcctgtaaa ggatattacg gttatcggaa
    14641 aaccattcaa ctggggattc tttttcctcg gaagagatcg aggactttcc ttttattggg
    14701 cgatgaaatt agtcgtcatg gtcttgcttg gattcgaagt actgatgata ttaacgaaga
    14761 ggaaaaaagc tctatcgcta atcggtgcat ttgcgctgac attttctcca gcagtccagt
    14821 ggtggttcat gcaacatgtg ggcgatttga ttttctttac tttgggactg atgattgctt
    14881 tttatcatta tttctacaat catgataaaa aatggctacg aacgttgatg atgcttttgg
    14941 tggttatttt cggtattggg tttattttag tgatttaccc agcccatcaa gtgatgctgg
    15001 cgtacctgct gattttttat tttgttggcc tgcttattta ctatagcaag aaagtttcat
    15061 gggatctgtt ggatgtagtg ttgattggag gggcagtttt atttattggc ggagtcatgg
    15121 ttcatttctg gctaacgtca aaagacgcat tgttagcttc tttgaatacc ttatatccag
    15181 gaaaacgggt aagtactgga ggaaagtgga cgattggcga atttttttct ttccttacaa
    15241 attggaaaat tccttttgaa gatatcaact attcgaataa ctctgaagtg gccctgttct
    15301 atcacttttt tccaactgta ttcctagcaa gtccatttgt gttatttggc aaaaaagata
    15361 gcgaacaaaa gttactggga cgtattttga tgattttttg tctgttttct atcttttgga
    15421 ttaccgttgg gttgccaaaa tggctagcag aaatcactct gctgtcttat gttcctccat
    15481 taagagccat ccttactttt agttttgcgg cttgtttatt atcgatctgg tttatcgctt
    15541 atatttggag agaagatgtt attcctattt ggtataaatt cattttgttg gcagtaaatg
    15601 catggtctta tttctatgcg attacgcatt cgaaaatgga taattatttt tcggattttg
    15661 aaaccatcgc agttgctgtg ttgggaacag tgattttagc ttttgcatta tttggctgga
    15721 gacgcttgtt ttacctcgct tttgtcgcct tagttatcgt atctggcttt ttcgtcaatc
    15781 cagtcgtaga aggtacagga gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa
    15841 tcgatcaaca agatcctggt aaagtttggt tgtctgaaga tgaattatat aacttcaccc
    15901 caacattggg agtgaaatcc ttcaatacag tacgctttta tccagatata gctgcatgga
    15961 agaaaatcga tccgaaagaa gaatacgaga agtattataa tcggtatgct catacaagag
    16021 cttttatcgc taaggaagat acaaagttca ttttagatcg tccagatatg ttttcggtca
    16081 cgttgaattt tgaagacgca gaaaaattag ggatcgacta tgtgatcagt aaacgaccat
    16141 taactgatta caaccaatta tatgaagcgc agttcacgca gctatatgga ccggataaag
    16201 acggttatat gatttttaaa gtagaatatc cggattatcc agatgtacca caaacacaaa
    16261 ctcaggaaaa tcagctagtc gtacagtaat aggctagctg agaataatcc tgaaatatta
    16321 gtagaaagga gagtgaagat aattcaagca atcgtacaaa aatttgtcaa caaaatgagt
    16381 gtcggtttct tgcttttgtt gctgacgcta gtcttttttg tttggacagc aggggtaggt
    16441 tttccagcaa ctttgtttat atataacaat agttcattac ttatcgcttt tagtgtggct
    16501 attttgctca ttttaaatgt ttataaagca aaaggcgtcg attttcttta tctaggtgtt
    16561 gcgcttgccc ttttcatttt cttttcttac tttcgggaat taagaaatga gtctttattt
    16621 ggagacttac tgtttccttt gattatttta ttttgtttag taattaaatg gatcgagtgg
    16681 acaaaatggg atcgcggtat ttatctgatt gtctttacgg tcttcctcgg aatcacgtta
    16741 tatcgtgtat ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat
    16801 tcgctttctg atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct
    16861 ttattgatca gtggatttgc cagttctttt gaacgatggt atgttcgaat catcggtggg
    16921 atagcagtcg ttgcagcctt tttaggtatt tgggtctgcc aatctagagg tgcattagtc
    16981 gcgttgattg tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt
    17041 gcgccattta ttgcctacac ggttacgatt cttttagctt tgccgatttc ttatctggcg
    17101 gctgtctctg aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat
    17161 cagacgctag gagaaaaatc tgaacaagtt ttactaggaa tgaaaacatt tatcttccag
    17221 cgaggaaacc aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga
    17281 ttgataggat ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg
    17341 aaagcagatt tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg
    17401 cagtcattta tggaggatac attgacttca taccgatggg ttccgattat ttatatcctg
    17461 ttggctatgg ccgttcatcg atatgatgaa ccagaagtta cggaggaatt ctatgttatg
    17521 gaagaggcat atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc
    17581 gctcattctt ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg
    17641 acaaccgtcg cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa
    17701 acgttagaga aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta
    17761 ccaaaaatat ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac
    17821 aaatgtttaa agatttgtat ttatttatga aggacattta tcagaacaga aaattactgc
    17881 tacagttttc gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat
    17941 gggcgtttat caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac
    18001 tgaaagcaca aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga
    18061 ttccctggtt cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata
    18121 cttatttagt aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat
    18181 ccaatctgta cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg
    18241 gtatatatcc ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt
    18301 tcttgacagg attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc
    18361 aattaattac gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta
    18421 atcagtttga ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc
    18481 aaggttatcg tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt
    18541 tgtatttctg ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat
    18601 tgaaaccaca tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag
    18661 actaaaagat atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga
    18721 agccctcaat ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa
    18781 tgtagaaata aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc
    18841 tacaatgttg aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga
    18901 aggaaaaatc tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta
    18961 tgaaaatatc tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat
    19021 ggtcgatgat atcattgaat ttgctgacat cggcgaccat atttatcaac ctgtaaaaac
    19081 ctattcaagt gggatgttcg ttcgtctagc ttttgctgta gcgatcaatg tgaatcctga
    19141 tattttgatt gtggatgaag cattggcagt aggagatctt gaatttcaac taaaatgtat
    19201 ggaaaaattt acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat
    19261 tagttcgatt cgccgttttt gtgatcgttc ctattggttg aaaaatggaa aagttgtcga
    19321 atatggtgat acgatggaag taacgacgaa ttacgaaaac tttttgaaga aaaaatcagt
    19381 taaaacagta gatcgaaata aaaaccaagt agaacgcttc gcagctccag atatcgtaga
    19441 cgtgacgaaa gccgaattgt tggataaaga taaaaatcca gtggatatgc tggaacaagg
    19501 agaaaaacta tacgttaaag taacctatga agtaaaagac gatacaatca aaaatccagt
    19561 tttaggaatt gctctgcgta cagtcgacaa tttttatgtg tgcggactca atactctact
    19621 agatggtatc aagatccctt ggaaaaaagg tgagaatatc ttttatctgg agtatgaaaa
    19681 gttaggtttg ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac
    19741 ggttcctttg gtatacaaga caaaatacat gaacttgttt gtcagcggtt cttatatcgg
    19801 agaaggcatc gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg
    19861 attttgaaat ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac
    19921 caggaagtaa agttttagag tttggtcctg gaaacggccg attaacgaaa catttgatcg
    19981 gagcaaaaca atgtgaagtg agcattgtcg agctagataa ggaattgttc gattttgtca
    20041 gcgagtttgc ccaagatgga ttttatggag atatcgaaag ttttgaatgg gcaaactatt
    20101 atgctggaca aacatttgat tacgttttgt ttgccgatgt tttagaacat ttggtagatc
    20161 ctggaaaaac gttgaagaaa gttagagaat ttttgaatga agaaggagaa attctaatta
    20221 cattccctaa ccttgcgcat aattctgtca tgattgattt gttcaataat caattgccat
    20281 gggcttctta tggtttgcta gatgaaaccc ataattcttt ttatactcat gatggcttcc
    20341 aaaaagtttt tgaaaaagca ggattataca tcaatattga agattatttg tacttagctg
    20401 taggtgatac agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgttatgatt
    20461 tcaaaatgcg accatttggc gaagtctacc aatacttctt ctcattgatg aaacatccag
    20521 tagcacaaag ttccattgcg cagccgcaaa attctaatta tgtgaaagta ttagaagtaa
    20581 tccagcaaac gaaacaagat gaaataattc aacaaatacc attcaataat ttcacagggg
    20641 aaaatgagac actaagtttc catgtatcag aattagcaga acgaatggtg tttcgcttcg
    20701 cgcagcaacc tagctttatc gaattcagcg cagaagctgc tggagaaaaa ctcacattta
    20761 tcgattcaaa tgctgtagtc aaaacagtaa atgattgtta tttgtttgat ggtaaagatt
    20821 taccagagtt ctttttaacg gatattgcag ggaaagaagt gactatccat tgtcactatc
    20881 gttttatcgg agaattgaca ccaacaatga aagaattgct ggaaacaatc cgtccaatgg
    20941 ctgaagttac aaagcagctt tctgagaaaa atgatgaatt agaaagagaa aatcattatc
    21001 ttattgagaa taatacaaga ttagatcaga cgttgaaaac aaccataaat cgctattgca
    21061 cgttgttgga aagtgatgaa tggacaatca aacatagatt agggcgacgt aagaaagaaa
    21121 catcgaaaaa aatccaagaa aaagagcttt ctctatgtat tgacgaaaaa atctgggatg
    21181 cagaaacaaa gatattgaaa atcatcgggt ggggaatcgc taattcggat cgccaaccat
    21241 tgtcctataa gttatcagcc gaccaatcac cattttttga agcaattcct gttttacgag
    21301 aagaagtcaa tcaagcaaaa cagctagctg aaggagcaaa agcaggattt gaactgcgga
    21361 tcctttgcga gaaggaacgt tcattcttag ttgaagcagt ggctcaaaat ggtcaatcat
    21421 ggatcattga aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca
    21481 aaaaaaagaa attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt
    21541 gcttattgtg ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga
    21601 aaaagaaaat gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata
    21661 taatcttgat gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg
    21721 aaaagcaatc ttagacttcc aaacagcaag acatcaaaat ggcatagctg tgaaattaaa
    21781 cggtaaatat ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact
    21841 gaaaaaaggg ataaattatg caaggactca tggcgtaaaa aaagcaatcc gccgggtcaa
    21901 actggaattg aaaccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc
    21961 tgatctgaaa gagcaaagga aagaagtaca aggatttgcc taccgcccat tgatttccat
    22021 acttatgcct gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact
    22081 tgatcaaacg tatgatcact gggaactatg tatcagtgat gatgcttcta ctgatccagc
    22141 tatccgaaag tgtctagaat cctatcaagc aaaagatgat agaattaaag tcgttttccg
    22201 acaagaaaat ggacacatca gtctggcaac taattctgca ttggaaatgg cagaaggaga
    22261 gtttatagcg ctcttagata atgatgacga attacctcca tttgccttat atgaagtggc
    22321 aaaagtgcta aacgtacatc cagaactgga tttgatctac agtgacgaag ataaaatcga
    22381 tgcagatggg aatcgctttg acccgcactt caaagcagac tggtctcccg atacattgat
    22441 gggaaataat tatatctctc acttaggcgt atatcggaca agcattgtta aggaacttgg
    22501 cggtttccgt aaaggatatg aaggctctca agattatgat ttggttcttc gtgtgacaga
    22561 acaaattcct gcagaacaca tttaccacat tgaccgtgtc ttgtatcatt ggcggacgat
    22621 cccgggatca actgcaagca atggagaagc taaaagctac atctatgatt ctggagtgaa
    22681 agcattgaca gatgctctat ctagaagaaa tatcaaggga agcgtacatc ctggcagaat
    22741 ttctggtttt tatgaaatca cttatgatgt tttgcaagaa gacttggtca gtgtgatcat
    22801 tccaactaag aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac
    22861 gtcttatcca aattatgaaa tcattattgc agataatgga agtacagatc ctaaaatgca
    22921 agaattattt gcagaataca agcatcagct gaaagaccga tttatcgtcg aattaattga
    22981 cattccattc aattattcac gtatcaacaa tctggcagca gaaaaagcaa acggcaaata
    23041 ctttttattc ttgaataacg atacagaagt gattgaacct gactggatga cagcgatggt
    23101 ttcttatgca cagtttgatc gaatcggctg tgtaggagca aaattatttt atccggatga
    23161 tacaacgcag catgcaggtg tattattagg gatcggtggc gttgcaggac atgcattgaa
    23221 taactatgat cgaacacatt gtggttactt tggccgattg gtcattgacg tcaattactt
    23281 agcagtcact gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg tcaatggatt
    23341 tgatgaaata ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact
    23401 gggtcgttac aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag
    23461 aggttatgaa gatacaccag aaaaacaaag acgttttgct ggggaaatca aaaaaatgca
    23521 agataagtgg ccttcttata ttgctcatga cccattttat aacgataatc taactaaaga
    23581 aggaatcggc gatttttcgt tgagacctga ttgattaaaa gaactgtatt ttcattttta
    23641 ttaatgaaaa tacagttctt ttaatttaa
//
LOCUS       DACGLI010000048        22991 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.049, whole genome shotgun sequence.
ACCESSION   DACGLI010000048 DACGLI010000000
VERSION     DACGLI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.049"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(152..1573)
                     /locus_tag="IXT22_002079"
     CDS             complement(152..1573)
                     /locus_tag="IXT22_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4863415.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1816..3693)
                     /gene="tdc"
                     /locus_tag="IXT22_002080"
     CDS             complement(1816..3693)
                     /gene="tdc"
                     /locus_tag="IXT22_002080"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4863416.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3984..5240)
                     /locus_tag="IXT22_002081"
     CDS             complement(3984..5240)
                     /locus_tag="IXT22_002081"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAQ4863417.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5820..7121
                     /locus_tag="IXT22_002082"
     CDS             5820..7121
                     /locus_tag="IXT22_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4863418.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7190..7789)
                     /locus_tag="IXT22_002083"
     CDS             complement(7190..7789)
                     /locus_tag="IXT22_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4863419.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            8043..8924
                     /locus_tag="IXT22_002084"
     CDS             8043..8924
                     /locus_tag="IXT22_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863420.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8937..10547
                     /locus_tag="IXT22_002085"
     CDS             8937..10547
                     /locus_tag="IXT22_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAQ4863421.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10624..11283)
                     /locus_tag="IXT22_002086"
     CDS             complement(10624..11283)
                     /locus_tag="IXT22_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4863422.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11566..12231)
                     /locus_tag="IXT22_002087"
     CDS             complement(11566..12231)
                     /locus_tag="IXT22_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863423.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12378..12983)
                     /gene="dhaL"
                     /locus_tag="IXT22_002088"
     CDS             complement(12378..12983)
                     /gene="dhaL"
                     /locus_tag="IXT22_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAQ4863424.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(13011..13994)
                     /gene="dhaK"
                     /locus_tag="IXT22_002089"
     CDS             complement(13011..13994)
                     /gene="dhaK"
                     /locus_tag="IXT22_002089"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAQ4863425.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(13996..14391)
                     /gene="dhaM"
                     /locus_tag="IXT22_002090"
     CDS             complement(13996..14391)
                     /gene="dhaM"
                     /locus_tag="IXT22_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAQ4863426.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14545..14865
                     /locus_tag="IXT22_002091"
     CDS             14545..14865
                     /locus_tag="IXT22_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAQ4863427.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14977..15846)
                     /locus_tag="IXT22_002092"
     CDS             complement(14977..15846)
                     /locus_tag="IXT22_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4863428.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15942..17246)
                     /locus_tag="IXT22_002093"
     CDS             complement(15942..17246)
                     /locus_tag="IXT22_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863429.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVSFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17243..17752)
                     /locus_tag="IXT22_002094"
     CDS             complement(17243..17752)
                     /locus_tag="IXT22_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863430.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17927..20062)
                     /locus_tag="IXT22_002095"
     CDS             complement(17927..20062)
                     /locus_tag="IXT22_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4863431.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20145..21800)
                     /locus_tag="IXT22_002096"
     CDS             complement(20145..21800)
                     /locus_tag="IXT22_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863432.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21802..22116)
                     /locus_tag="IXT22_002097"
     CDS             complement(21802..22116)
                     /locus_tag="IXT22_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4863433.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22286..22546
                     /locus_tag="IXT22_002098"
     CDS             22286..22546
                     /locus_tag="IXT22_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAQ4863434.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22560..22874
                     /locus_tag="IXT22_002099"
     CDS             22560..22874
                     /locus_tag="IXT22_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAQ4863435.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
BASE COUNT         6491 a         4731 c         4134 g         7635 t
ORIGIN      
        1 aaaaatctga gccagaatgt ggttcattct gactcagatt tgattttgca caactcatca
       61 gtccttattg acaaagagcc gaaaaaacta ttcacttggc aggacctcct actaaatcag
      121 cgacaaaacg tcggctgaaa gacttatttt tttatttttc ttctaaactt ttttctacct
      181 caatccccca agaatctttc ttgaagtgat tgatgatcaa tggaataacg aacatgacca
      241 ctgtgatagc tgctactaat aatgcatcac tcaatgtcgc tgtacctaat gtagcaaata
      301 cgacaacgat gatagagaag atcagcatgc agctgactac ccaagctaat ccgtttccgt
      361 ttttaccaat tcggtaagga cgttcgaatt ctggatgttt cttacgcatt ttaagcaatg
      421 aaacagcaat caaaatgtac acgatacaat aaataacagt tgtagcattt gtaagtgtca
      481 agaatacagc acttacgtca tccattacac cataaagcaa agcaaataat gaaataacga
      541 ttgattgtgt tagaacgaca tttctagata cgccgtattt gttttcttta tggaatccga
      601 attttggtgg aaggaatcct tcacgagcta cttggatgat tgtttttgat ggtccagtaa
      661 cccaagctga taattgtaaa agcacaccaa taaataccat gaagctgaag atatttccga
      721 tcacttctgg taagcctagg atttgacagt caatcaagat aggctgcgtg atatttgcta
      781 attccatttt tccatctggt acgacatttg ctacaagcat cgcattgatg acattcaata
      841 aaactaatcc gatcaaagcg ataaatacgc cttttgtata attttttgtt gcgtctttca
      901 aacgaggcat gtaaacagaa ctcatttcga tcccaacaaa aataaatgtg ataccagcta
      961 agtatttcaa tgaatcaata tgttccaagt cagggaaagc ttttgaccat gaaaagtcac
     1021 ctagatagcc gtttgagact agtccgactt tgaaggctgc caaaacacct aaaacgaaca
     1081 tgatgactac tgggatatat acccctagcc atacaccgat gttcccgccg acttttgcca
     1141 tatcgaattt caagttcaag atcgtgatga tccagtagat aactaaaata caacctaaaa
     1201 cgaaccagtg attattgcca agttctacat taccaaatgt gtttcctaac aatggtccta
     1261 aagtagaagc gaccattacc atacctggga acatttgcac ccataatagc catgcaacga
     1321 caaatcccca tttgctgccc agtgctgttt ttacccataa ctgaggaccg ccttcttgag
     1381 gaagcatcgt ggaaagctca ccggaaacca ttgatatcgg accggcaaaa aacaaaactg
     1441 caaaaattga ataaaaaatc aatgtccaac cgactgcggc taacgtagga atactccgaa
     1501 ccgttgcaca cagtgccatt gtcagaccga taaaggtccc aagacccatt ttacttactt
     1561 cagatttact caccgttgac actctccttg attttttgga taaaataacg gtgtctttga
     1621 agtagtttca gcaataaacg aaacaattca gcgaatattt gaggggattc tttgagttta
     1681 ttgcttgaag ggtttcttca aagacaacct caaaacaaag ggatcgaaga gcttaggtct
     1741 ccccttgctc ttcagatcca aacatgcgtc agaaacagtt agtattcaag ctgttttcta
     1801 acatgattac cttgcttatt ttgcttcgct tgccaataat tggtctgcgt agattttttc
     1861 caatttttct tgaagagctg ctttgatttt ttcagcatat tcttcaaagt gttcttcttt
     1921 gttcatgtat ggtgtcatta cgctggcacg caatacagtt acttttccgg cacggttcca
     1981 ttcttcatct gagaatccta gttggttcac aaattgtaat gggctgttgc catagtctgg
     2041 gatagcaaag tcagtatgtg aagttaagaa ctcattaccg taaatgcttc ctttcacgta
     2101 tgaagaataa tcatatacgt catggttcaa tttattcatt gcaactaagt catcgttgcc
     2161 tttttctttg aatacatagt ctaccatatt gaaatctgga taagttaatg gatgaacttc
     2221 gatttctttg tctcctactt taaatgacaa gtcattcaag aagttgtaga aacgatgtgc
     2281 accttcgatt gatgcaccca ttaatttacc atatcctgtg acattcaaag gtaagacatg
     2341 gtgtgctgcc caaacgctgg ctgctgttgc ccctgctttt gaaccttcca agatataagc
     2401 cccaagtaat gctgggatat ctgcgccttt ttcaaataca tatgtcgcaa agtaagagat
     2461 aacgtctctc atgcggatat ctttgatgac gataccaccg gcagaatatg gaacatagcc
     2521 cattttatgt gggtcaatcg ttacagattc tgcttcttcg attgctttat atgcactgtg
     2581 tacttcttct aagatataat ctttgttttc tgtaaagaca ttgtatttgt aatgaacatc
     2641 ttttaaatct tcaaatggaa tgaagttgtt gtcttcgtct aagaaaatcg cacggccgta
     2701 tccgccataa gcagcatcta cgtgtaagta gaagtaaata ccgtcttttt ctaatacgcg
     2761 acgcaatgca acgattttat cgataccgtc gattgctcct tcttctgttg atcctacaac
     2821 accgactaca cctaggattg gtgttttttc agctgctaga ccacgaacga ttttttcaag
     2881 ttcgttgatg tccatgcgat agttgtggtc aactggcact ggaatcactt ggtctaaacc
     2941 gataccgatg atgtcggcag cttttagcca tgaatagtgt ttagtttgtg gaaccaacca
     3001 ttttcctaat ttttctaaat gttttccgct acgtgctgag tgagctttga tttcgtcgat
     3061 tttttctggg acgctgtcta acagattcat gatttcttct gttgacaagt tcattaattc
     3121 ccaatcgctt tttccagcaa ctagttcagg tgtcacttct ttcattgcaa gcggcaatga
     3181 tttgatgttg cgggcatacc aaagtccttc taagtttgct aaagaaccat cagcaacgat
     3241 gtggccccag ccatctttat agctcattaa ttttgcaaat tccattccta cttcttcttc
     3301 catttggctt gttgcaggag aagattcata ggcaacgtta ttaccattcc atagcatagc
     3361 aaaattgtac gctagtaaag atggcatcaa tgtttcagag ttcatatgac cccagtaacg
     3421 tccggcatta tgccaaggaa cggaatgggt acgcatccgc gctgaaattt ctgatagaac
     3481 atcctttgtt ttattcacag tgtgttcaaa actagcactg cttttttctt ctggcgtaat
     3541 aataggcatg tcttgaggca tgtagttttg acgccagcct aaatgttcat ccaccaattc
     3601 attcaacaaa gctttataga tttggccgtt ctcagctttg tccccaatga atagggcatt
     3661 taggtttaga tctttcgaca atgattcact catagtgaaa ccctcctaaa aaaatattta
     3721 aattttgtcg agccctacat tacacctgtt cttctattct gtaaactaag ttttggcctg
     3781 atttttaatc atattttaat atgtatcaat tatccgaatt gttcacactt ttgaaataat
     3841 taaaaaaaac gagggaattt acaaatgtaa actccctcgc aaagattgta ttaacgacaa
     3901 ccagcgttct attttaggat gggtttcaaa attggaatgt tgtaatagta tttccctttt
     3961 tcaaggtaaa aacttactaa attctaatca attactttgg ccaaaaagta atttttctta
     4021 ccttttcgaa taaccacaaa cttaccatcg aattcatcgg atggatttat gacaaaattt
     4081 aaatcggtaa cgcggtcacc gttaatactt atagctccgt ttgaaacatc ttcacgtgct
     4141 tgacgtttag atggttcaat ttttgtggaa acaagcagtt ccacgatatt ttcaggtgtg
     4201 cttgaaattt caacgttcgg cattttaccg aatccttgcg cgatttcttc cgcatttagt
     4261 tctttaatat ttccagagaa caatgcttgc gttatttttt gcgcttcttt caagtcttct
     4321 tcactatgca caaatcttgt aacttcttct gccaaacggc gttgtgcttc acgtttctca
     4381 ggttctgtct ctactttttt cgctaagtct tcgatttctt cttgagacaa gaaagtaaag
     4441 aatttcaagt atttcactac atcgcgatca tcttgattca accagaattg gtagaactca
     4501 aatggtgaag ttttcttcgg atcaagccaa acggcaccgc ctgcagtttt tccgaatttc
     4561 gttccgtcag ccttcagcat caatgggatc gttaaaccga acgcttctgc ttctggtcct
     4621 tctaattttc ggattaggtc taatccagct gtgatatttc cccattggtc tgctccaccg
     4681 atttgcaatt gcacatcgta tgttttatgc agatgcaaaa agtcgataga ttgcaggatt
     4741 tggtaagtaa actctgtaaa tgagattcct acttccaaac ggctggcaac gatatctttt
     4801 gctaacatcg tgttgatgtt gaagttttta ccgtagtctc tcaaaaattc aagtaaagag
     4861 atttttgaca accagtcgta gttgttcaca aatgtgatat ttgcatcttt accaaacaat
     4921 tttctcattt gattggaaag tgcgtccacg ttatgttgca cttgttccat cgtttgcaac
     4981 acacgttctg ttttgcggcc gcttgggtcg ccgatcgttc ctgttccgcc gccaatcaga
     5041 atatatggat gatggcctgc caattggaat cttttcatca tcataaatgg aatcaaatgt
     5101 ccgatatgca tcgaatcacc agttggatca acgccgcaat aaagtgaaat gctcttttct
     5161 tcaacgagct cgcgaagtct ttcttcgttt gtttgctgat taatggcgtc gcgccaagtt
     5221 aattcatcaa taatattcat tttactgacc tccgtgtagt ttttttatga aagcaggaac
     5281 ctgctagcat atgtaattaa ttatttcttc aggataggat aggaaataaa aaaagtccct
     5341 tggcatataa gccaagggac gaaatctcgc ggtaccaccc aatttgtatg tctagatatc
     5401 caacatacct ctcgaacatt taacgctgtc gcgtggcaat cactgccaaa gactcctgaa
     5461 atgtaattcg ctttaaagca tgtactggtt tgcagcgacc accagctttc tgaaacattg
     5521 gctttaacaa ctacttcgtt tcgatcttcg tcttgttatt attaatatgt gtctatcata
     5581 gagcgcaact ttttctttgt caacagaaaa aggatatttt ttttaaattc ctcatttttt
     5641 cttttttgaa tccgctctaa ttccgaacat tttattttca attattgtta aaagaaataa
     5701 ctttttctgt attttttctg caatttatcg agaagtcact ttactttgcc tcttattctt
     5761 tcttcgttac aataaggaat gggacaagta aaaaaatgaa aaagcaaggg acgaggtata
     5821 tggaaaaaaa gcaaaaaatt attttaggag ccacttctgc tttaactatc gttattttaa
     5881 ttctaagttt gttttttgtc atccgatcat ctacaaaaaa agaaccaatc attcctgaaa
     5941 aaaaaataac agaaaaagca aaagaaccga cagatgataa gcaacaacta gttactcaag
     6001 caaaaaatct ggctcaaagc tacgattatg accaagcgat tgcgttattg gaaaaagata
     6061 gtaagaacgg atctactgaa acacaacagc ttcttcaaac actaaaaaag gagaaagaac
     6121 aactgatcga ctggtctgat cctactcaga tctctcatgt ctttttccac agcttgatcg
     6181 tggacccgca aaaagccttc cactctcaac aggcacaagg atacaaagat tatatggtga
     6241 ctgttgaaga attcaaccgt tcgatcgaac aactttatca aaatgatttt gttttagtta
     6301 atttgaatga tttgatccaa aaagacgaac aaggaaatct ttcctttaac gggcttgcgc
     6361 tacctgaagg aaaaaaacca ttggttcttt cacaagatga tgtcagctat tatgaatata
     6421 tggataattc cggttttcct agccgattgg tcgtatcaaa taacaatgaa atcaaaaatg
     6481 tctataaaga gaaagataaa gaagaaatcg gtgactttga catggttcct ctgatcgatg
     6541 cctttgtcaa gaaacatcct gatttttctt atcgaggcgc aaaaggtacc ttggccctga
     6601 caggttacaa cggagtttta ggttatcgaa catcaaaatc tcaatatgga gacaatgaaa
     6661 aaacaaaaaa agagattaaa gaagctaaaa aagtggcgga acagttgaag aaagacggct
     6721 ggagctttgc ttcccataca tggggtcact tgaatatgac tcaagcttca ctagaagatg
     6781 taaaaaaaga caatgaattg tggcagcaag aagttgcacc tatcctagga aaaacaaata
     6841 ttctgattta tccatttggt gcagacatca gcgactggca gccttattca gcagaaaatc
     6901 aaaaatttgc ttacttgaag agtcaaggtt tcgatatttt ctgtaatgtc gatgcttcta
     6961 caccagcttg gggacaatta ggtacggatt tctatcgaaa tgctcggatc aatatcgatg
     7021 gcattcgttt tcaatctgat ttagacggaa aaaatcctat tcttgatcca ttcatcaatg
     7081 tccatgatgt ctatgacaaa gaagcacgcg aatctgcttg attttacgtc atttatgaac
     7141 caaaaaagcc gaactgacat tttatcgtca gtttcggctt ttttatgctt tatttcttct
     7201 tcggtgcgat tcccttgatc aggacttctg tccattctgc tgtatatgga agcagttttg
     7261 cgtatatctc cggcttagaa attccttcta ccattgcttg aaaatagagg atcaagaact
     7321 catccgaata tttcaaatcc acttttcctt ctttccgccc tcgatggaaa agatcaagca
     7381 tgatactgaa actttcttgc gtatacgcat ccatcgcgtc agaaaattct tttttttctt
     7441 tttttgtata gtatgtcatc aaatcgatat aaaattgttt gttcactcga ttgagataac
     7501 ggattttgtt ttcactcatg gcaatcagtg tttcttcaaa tggaagattt tccgcaatca
     7561 acgctttcgc ttcttgccct aaatcattca taaatgcaaa aaatacttca taaatcagcc
     7621 cttccttgct gccaaaatat ttaaaaatcg tcgctttact tacctgagcg ttctcagcta
     7681 ccttatccat tgtcactcca gcggttccta tgtctgtgtt catcaagtca aaagctgctt
     7741 gtaaaatctc tttctttttc tcttgtgctc tcttttcaaa accgttcatt tgtagagcct
     7801 cccgtaattt taaactttta taatatatat agttcaaatt tattctgagg tttattataa
     7861 ctatctattg agaaagtatc aagctagcaa ttccttgttt atgaattcat tgacagaaat
     7921 ttataaaaag aatattatgt actaaaataa taaaaaaagt tttataaaaa ggtataaaac
     7981 ctttttatta aactatttaa tcttgtttag tatatatttt tagaaaaagg agtggggttt
     8041 ttatggcaga aatcgtcaaa gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt
     8101 taaaagatgt ctctttcacc gtacattcag gtgaagtcgt tggatttatc ggaccaaatg
     8161 gttctggaaa atccacgacg attcggacac ttttagggat tataaaaaaa gacggcggaa
     8221 cggcaacgat ttttgggcaa gatgtatggg aagatagttt atctatccat gaacgtcttt
     8281 cttatgttcc aggcgatatc tctttgtggg gaaatttgac tggaggagcg atcatcgatc
     8341 tcttcatgaa gcttcatgga aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt
     8401 tctctcttga tcctaagaaa aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg
     8461 gcttgattgc tgctttggct gttgattcgg atctctattt atttgatgag cctacttctg
     8521 gtttagatcc tttgatggaa acgattttcc aagaagaagt tgaaaaattg aaagaacagg
     8581 gcaaatccat cctactttct tctcatattc tcagtgaagt cgagcgacta gcggataaag
     8641 tcgtgatcat acgcgaagga acactcgatg aagaaggaac actcgatgaa ttgcgtcatt
     8701 tgactcgttc gaccatcact atagaaacag aagcagagaa tagtcactta gcacaattga
     8761 acggtgtcca tgactttgtg caaaaaggtc acctcgctca atttgctgct gataacgaag
     8821 ctttcgatgt gattttagct gaagcgtcca aattaggtgt gaaaaaattt gaatctattc
     8881 caccgactct tgaggattta ttcatgagac attatgaagg atgaggagga agcgaaatga
     8941 ctgataaatt ttcacgctgg tccacccttt tttctcaaaa ccttagccgt gactggaaaa
     9001 agatcctgat atggctagtc ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg
     9061 aagaattgac ttccggacaa ggattagctg gattatacga aaccttgcaa aacccggcaa
     9121 tgattgcaat ggtcggacca actccagctt cgaatgctgc tgagtatact ttaggagcga
     9181 tgtatgcaaa tgaaatgttg cttttttgca gtttgtttgc tgctgtgatc tctgttttac
     9241 acgtggtgag ccaaacgaga aaaaaagaag aacttggtct gattgaactt attcgttcct
     9301 ttcgagtcgg acgtcaagca aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt
     9361 tgcttttagc aatatcgatc agctgtacga tgattttttt ccaagcggat tcgatcactg
     9421 cagaaggtgc ttggcttttt gggctatctg taggtagtat ggggattttg gggagtgccg
     9481 ttgcactgtt tgctgcacaa ctgatgccaa gttcagccag ttcgaatggt ctgtctttag
     9541 cgtttttagg tggactttac cttctacgag caataacaga tgtagctgat tcctcccttt
     9601 cgatgtggaa tcctttaggc tggtcttatt tgacctatcc atttacaact aacaactgga
     9661 ttcctttgct ttatttgttt ttgttcagtc taatcttgat aatcagttca tttgttttag
     9721 aggaacatcg agatttgaac accggctata tccccgaacg tgaaggaaaa ccgtatgcta
     9781 aacgttctct tttatccttg cgtggtttat tattctatct aaataaaggg atgacaatca
     9841 gttggcttat cacttttggt ttgatggggg cggcatacgg ctctatctac gggaatatgc
     9901 aacagttttt agaaagtaac gacttaatga aacagatgtt tatccaatct ggcgtctcaa
     9961 ttgaaaaaaa ctttacaagc acgatcatgg tagtcttgat ttgtctagct gctattttac
    10021 caattgctag catcaatcgt ttatttacag aagaaaccca cggacgtatg aatcagctgt
    10081 tcgcaacaaa aatttctagg aaccaacttt attggaccaa tatgttacta gctattctat
    10141 ttgctatatt ggcaatcctg attagttctg gtgcactagg gctttctgct ttggcttcga
    10201 tgaaggatgc gaaagacatg gatctattga tgtttcttaa agccgggttc aatttcctgc
    10261 ctgccgtttt agtgtttatc ggaattagtg gctttctatt cggatggctt cctcgaatcg
    10321 gtaaacttgc ttatatctac ttagcttact cctttgcact caattacttt ggcggaattt
    10381 tggatttacc agaatggttt tccaaaacag ctgtccctag ctgggttcca cggatgccaa
    10441 acgattcttt tgatctttcc gtgttcctta cgttatcatg tatcagcctt gcactgttcg
    10501 tccttggttc tattggttat aggcgaagag acttactaga aggataataa aaaagcatgt
    10561 acaatttcat gctagcctcc aaatctgggt caaaaatcca acatttggag gtcatttttt
    10621 tatttacaag tcttctaact gctctttatc aatgatccag acttctcgat tctttctttt
    10681 tacataacca ttctcctcta ataatttaaa ttttctagat aaagtttcgg gggtcgtacc
    10741 gataaatgca gcaagttctt tcattttcat tggcaggaaa aagtgatcct tccctgtcgc
    10801 tttagctaag tcaagcagat agacagcgac tcgttcttct actttttcca tcatcaaaaa
    10861 agttgtctgc tgctgtactt ttgttaattt ctcaacgttg attgctaaaa gtttcagact
    10921 aagggcggga taatgcagta agagttccga gaaatctttt tgtctcaata tgcaaatttc
    10981 cgttttttct agtgcttcgc caaataaaga ctcatttgga acgcctagca actggctctc
    11041 tccctcatat ccgcccggct ctattactcg taaaagctgt tcctttccgc tagcagataa
    11101 ttgatacact ttcatactgc cggaggccac gatcactaat tgaggttctc cattcggcgc
    11161 aagaatctgt tctccttttt ccacatagtg atgtttgaca agtgcgtgta ctttttcttg
    11221 atcttgctgt actaagtgat tgaacaaagg aacaaatgaa acacataaat gatcatgact
    11281 cataatctct cctccttcta aacagctatt tctaataaag aaacataact tcccttattc
    11341 caactgataa ttttctttta tcatagcata aacgtcaagc gaaccagata ccagcaaata
    11401 gagtggattt ctttttgtcc cttgctttat tttccttctt ttgagacctt aagtaattga
    11461 ttcctatcaa ttttttaaat atttactttt tgaataatca aaaacaaacc ttcactcgca
    11521 agccgagagt aaggtttgtt tttcgcattg cttatttcgt gttgtctatt gaaatttttc
    11581 cgcacctagc ttttgatata gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc
    11641 aacgtgttcg atttcttgcg gatagaagaa tagtttaccc atttgaaagg ttcggtctct
    11701 catcgctttt ttcaactctt cttgtttctt tgtatcggac aaatagtcag acaaagctaa
    11761 gtggtcgtca agttcatgtt ctggttgcgg ccatatgtaa taatccttga tatcgactgt
    11821 tttgctccac tctttcagta tcgcaagcaa ctggttatac gctgcaatgc taccatatcg
    11881 ttcttcgctt ttataatgtt ggtacatcaa atagatttgg tattgttttt gattcaacaa
    11941 aactgctaga caggcattct cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg
    12001 actgcgtaaa ttccagccat tcgtccagct ttcgatttta ggtttgctca tgccgtacat
    12061 atcaggcaaa agtgcagctg tctggagctg aatctctttc catttttgcc agtgttcttt
    12121 atattctttc ttgatttgtt caatcttatc tgttggatgg ctctctttga gctgtttgaa
    12181 tgcgtagatt ggtcgatcaa acaactgata atctgatttt ccaagttcca ttgtttcgcc
    12241 tctttccgtt atcttttgta ttctacctga attttgcgat atggacaaat agaggttgtg
    12301 aaaaagctgt tctgcatcaa gtcataagaa cagccaaaca aaaaactgcg atgagcatca
    12361 ccgcagtttt attgaactta aggttgattg atcacatcta aaagcgttga aaataaaatg
    12421 gcactagaag cagctcctgg gtcgatatgt ccgattgcac gctctcctag ataggaagct
    12481 cgtccttttt tagctaccaa gactttggtg tgttcttttg cctggtcaat gatttctttt
    12541 gttaaattcc ctgccttcaa tgcctctgtg actggcagcc aaacatctaa catcgtttta
    12601 tcgtcagctt ctgcctttcc tcggctttga atacccgctg ttccctgctc gatcacttcg
    12661 cctaattttt cttgagaatc aatagaatcg acctcttttg tcgctttcat catgttcatg
    12721 aatgcagatc cgtataacgg accagaagcc ccaccgactt tcgatatcat cgccatagag
    12781 aatactttga atgtatcgct gattgtttca ggatgatcgg cttgaaaagc ttcttcataa
    12841 gctgaaaccc ctcttcccat gttatttcca tggtctccat cgccaatcgg ggtatctaga
    12901 tcactgagat attgtttgtt ctgattgatt gcctctgcaa attgcgtgag ccattcttgg
    12961 atttcttgaa cggttagttt catattatca cccttttatc ttgagatttt ttaccatgaa
    13021 atcgtctgta cattgctttc taaagaatct ttccattgtg tctccgtcaa gtcgatcagt
    13081 gttagagaaa gaccttgcat atctagtgag gtcataaaat taccgacttt tcggaaaact
    13141 acattgacgc ctctttcttc caacagagct aaaacatcat tcatgaacac gaactgttcc
    13201 atcaaaggcg tcccgcccat tccgttgact agtacacctg cttcttttgg taaattcgag
    13261 taatcatcta aaatcttagt aacaagttcc tttgccagta ctttagaagg ctgcatcttt
    13321 tctcgacgat agcctggctc accgtggata ccaacaccat actcgatctc atcttctcct
    13381 agttcgaatc ctggtttccc tacttctggt acagttgctg ctcgaagcgc tagaccgatc
    13441 gtcttagttg cctgtacgac cttttctccc agttctttca actcagctag ggaagcaccg
    13501 tttcttgctg catcgcccac gattttgtgt acaaggacag tacctgcaac tccgcgtttt
    13561 ccagcagtat acgtactatt ttcaacggcg atatcatcat ctacgatcac actttctact
    13621 tcaatatcgt ccatagcagc taattccttt gccatatcga agttcaatgc atcccctgta
    13681 taattcttaa cgatcagcaa aactcctttt ccactatcgg cttccttaat agccgtctga
    13741 atctgatctg gagttggaga agtaaacaca tcaccaagca ccgctgcact taacatccct
    13801 tcccctacaa acccggcatg ggatggttca tgtccgcttc ctccaccaga aaccaaacca
    13861 acttgttccg ctttctgatt cttggctaca acacgggaag attctacacg atgaacaagt
    13921 tctggatagc tttttactaa tccttccagc atttcttcga caatattgct tggatcattc
    13981 atgatttttt tcaatttatt cccatccttt ctttccggca ttttgtgctt ctgttaagat
    14041 ttgctgagta tcatctgtta taccggcagt gatggctgct gcaaaagctc cttccactaa
    14101 aggcgcatcc accagatgat aacgttgctg ctgctcttct tccaacatgt cttttgccag
    14161 ttccgagttc aataccgcgc taccgatatc cgcaaaaaca aaataactag ctgcatcgct
    14221 tgattcattg actgcttcta cgattttcat cgggtctgat ccgatctcgc catttattcc
    14281 gccgagagaa aaaatttgca cctcttcgga tttttgcatc tgctcaatca tttctttaat
    14341 accatctgtt actttttgac tatgagaaat aagcaaaata ctttttttca caagaatctt
    14401 cctttctttt acatagttgc taacgattgg tttcgctttc attaatgaac aattcaagta
    14461 tataataaat ttctaatttt gggaaaatat gtgtagtgct tcttgaagtt tgttatactt
    14521 taattaaaag agaggagtga tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa
    14581 gccgtagtag cttataaagg gatcgttttt ggtgaggtca ttactgggat ccatgcattt
    14641 aaagacttgg aggcggggtt gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac
    14701 gaactaatgg gtgcaagaga agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta
    14761 ggagctgatg cgatcattgg cgtaaaaatg gactatgaag tattaggcag cgacaatggc
    14821 atgctgatgg tcacatgtag tggaacagct gtctccacga gataagtagg ggacatctgt
    14881 tttaataact aaagagagat gggacatgta gtggcactca agaattagat ttttcagtct
    14941 aacttcgagg tactctacct tcccatcctc tcttttttat ttctttttgc ggatgattcc
    15001 gtaagctgct gcgactaaca cacccgcccc tgctaaggaa taactgacag aagctgtttt
    15061 ttcatttgtt tttggcaaag tctgacttgt tgatttggat ggctctgtcg tttgctgaac
    15121 tgtttctgtc gtgcttccag aggtcactga tttttctcct gccgaatgca aaatatcttt
    15181 tattcgttgg aaactagctg ctaagtcagc tttttttgct tcaaaatcat tagcaactgt
    15241 ttgtgcttcg ctgatctttc cgtggattgc ttgactggcc gctgtgatat ccgcttgagt
    15301 ttgacttagc tttccagaag ctgtttgagc aacctgattt aattgctgat tgaattcttt
    15361 tgcttgttgg atcttcccgt caagatctgt ttggacagct tccgcttttg ctttcgcttc
    15421 ggcaagcttt ttctcaagtt gtgcacggtc atttcccact ttatttttaa gatcagctaa
    15481 atcttgatcg attgctgctt ggtcttcttt caatttgttt tttgcagctt ctaatgcttc
    15541 ttcgagttct tttcttttat tttccaagtc ttgcaaatga tcgatttggt cagaagaggt
    15601 agaactattt attgatgtat cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg
    15661 tacattggaa gtcatttctg tttccgaggc accgttttca gcaccagaag agcttatggt
    15721 tgttgaaggt tctgtttgag caggttcaga agtttccgca aaagctgtct gtcccaataa
    15781 gaaaatactg gaaacagcaa ttggccagat taacggcttc attctttttt tcatcacttt
    15841 tcccatcctt actacttttt aactaatttc ttattataag caaaaatgtt tggaagaacc
    15901 ataaacacaa caggctgttt gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc
    15961 gggcttttcc atgtcccgct tccataacct aaaatcgttt tgactgctgg aatgaaagtc
    16021 gtcacgatcg ttatcgcgtt cactatccag aacaaaagca tatatagtgg tgcgaaaaga
    16081 aggtatttca attttcttcg tcgatcatct acaatcagcg aagctagcaa ctggaaaaat
    16141 cctgcgacca tttcaaagca gatgaacaca aaactgaatg taaaagtaat ataaatctgt
    16201 tcgtagtttc cttgatatac ataatgcccg attaatccag caaaaagaac tacggaaata
    16261 caaaagaata ttgaccagac aatactcaat gtttgatcaa tgaagatgat cgttcttcca
    16321 atatgtttaa aaggatggag catcactttt ttgaaattcg tcagccagac ttctgttcca
    16381 ccttttgccc aacgttttct gtgtcgatat agcatcttca acgtcacagg tacttccatg
    16441 aaaaagataa tctcaggagc aaaaacagat aaccagtcat ttaactgatg atcccaagca
    16501 atactgatgt cttctgtcgc tcgatcttgt ctgaatccgc ccacatcgat caaggcttct
    16561 tttcgataca tcgtatttgc tccactgtac gcataaagac caccgaaaac agctgactgt
    16621 gttcgtttaa tgatgcccac gatacttgag aattcaaccg tttgagattt tgcaatcaat
    16681 ttggtacgat tttggacatc catatttgca gtgaccgcag caatatgtct tgcaccaggg
    16741 cgaatgaaat aattcacata cctaatcagt gcatctggct ccggtaccgt gtctgcatca
    16801 ttgcttaaaa tcaatttccc ttttgcaaag gcaagtccga tattaaacgc gtgggctttt
    16861 cctttatttt tttcgatccg aaccacacga agattagcgt attttttcat cagtctagct
    16921 aatatttctg gtgtttggtc cgttgaacca tcgtctgtca ctaatacctc atagttgtga
    16981 taattcaatt tcgtcatcaa atactcgatt gtatattcga tcacaatttc ttcattatgg
    17041 gctggcacca tgatcgtgat gaacggttcg acactcaagg gaacatctac ccattctttt
    17101 tgcttatgtt tgtataaaaa cacataacac cagacaccaa taaacgatac aaatccgcct
    17161 aaaatcggat aagaaacgag aaaaaaatac ataatagaca aacaagtatc taagaataaa
    17221 ttacctgtat gggtgattga gatcatttca gttccacccc attttcttta tacaaatctg
    17281 caatgaatgt cgtatctaga tttttctctt cggagacaga ataaaaacgg accgtttctc
    17341 tctcttcttt tgttccaaaa cgttccgtat acacttcttc aagtaattct tgtctttttt
    17401 tcaatttttc atcttcatat tcaaaagatt tatttacttt tttgtataga tttcgattgt
    17461 tccacctagt caatacaaat gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc
    17521 cgattaagaa atacagcatt ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg
    17581 ctctttctgg tctcgttaat gggaaaaaga cccatataaa aggaagaaca acgatcatcc
    17641 atcctaaaag agccactaac gtttgccaaa tctttaacca gtaattacct tttgaaaaat
    17701 acttatcttt caccaaaatt gatgcaactt cttctcttgt tacttttttc atatcctcac
    17761 ctcacgtttt tttgttacga cgtaggagtt taccatacat ttcatttctt ttcacataaa
    17821 gtgttcctaa atttttccta agaaaaagaa caaaacattt ctcatcagca aatgaaaaat
    17881 attttgttct ttttatcagt tgttcttttt attttttatc tcttaattat gttgctcttt
    17941 ccaatacgac aatgcttttc attcctctag atatcgccgt gtacatttgt ctgcgtcttc
    18001 tttgctcatc tccatcgttt tcaaatggat ataagattac atgatcaaat tccagtcctt
    18061 ttgctagact caaaggaatg atttggcagt tttctaatcc atatgaattt tttttaatcg
    18121 attcttgtag cgtttgggtt tcctcttctg tttgggtgat aactgccgct ttttctcctt
    18181 ttagagaaac caaaatctca gctagtattt tcaacaattc ttcagaggat cgaaaagagc
    18241 ggtattcggg ttcttttcct tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca
    18301 cagcataggt tttgaaaagc tctgtgattg ctccgctaga acggtaacta tttctaagat
    18361 cataccgatg gatcggcaga tggtagtcgt cgaaacaacg cataatatca gcaaaagtag
    18421 tggaagaatt aaagattgcc tgattctcgt cacctactaa agtaaagtga gtttttggaa
    18481 ataattcgat caatagacct aattgtgcca gggtataatc ttgtacttca tcaatcaata
    18541 gatagcgaaa tgctggtaca tttacctttt caacaagtaa atgacgaata gctaatataa
    18601 tgactgcttc atcaacagta cgtgtgggtt gccaagcata agctgagcca tatcgttttt
    18661 cataaattct ttcaaacaac tgatgctcat ccacccatgc catttcttcg atttgtctgg
    18721 ttatttttcg atattttttt tgtaaaagtt tccttgcata agctacaata ctttgttccg
    18781 aatcatcaga aatcaattta ccgaataatt ccaactgcct atcttctgtc aacgagagta
    18841 cctgattctg cacagcagga ctttttgctt gtttcaaaag atgattcttc cattcgctca
    18901 tcagtgcctt tttcgttgct tgaagcctat cgatcaattt aggatgagca ggaactttct
    18961 catatatttt ttcgatcgtt tttttagaaa ggactgtttt tccattttta gtaagtccac
    19021 ggataaaatt cggatgatct aaaaacaaag gatctgattg ttttagatta tcgataaact
    19081 ttttgctacg caaacgttct gtctgctccg atacattttc tcccgtgata cgtttgaaat
    19141 aagcctcttc accttctatt tcctctgctg aaagctgtga aaccagctgt atgatggtta
    19201 gattcagtgg atttctttca cctaatgatg gtaggacatt cgaaatatag tcgataaacc
    19261 gatgattagg tgatagaatc agcaagtcat cggatgtcat cgtatctcga tataaataga
    19321 gcagatacgc aatacgctgc atgatagcag aggttttacc acttcctgct acgccattta
    19381 ccaagatatt ttgacttttc acatcccgaa tgattgtgtt ttgttccgat tggatcgtag
    19441 cagtgatagc cttcatttca ttggtctcat cttggcctaa gacttctaat aatacgtcat
    19501 cttgaatagc tacagacgta tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt
    19561 gtcgtctttc tttaataacc gtatcgattt tattttgacg aaccgtataa gaagatggac
    19621 caatcatgtt attgtaaaaa agttcggcaa ttggtgaacg ccaatcataa acaagatttt
    19681 catctgcatc atctgtgaaa tttgctgtac cgatataaaa ggattctttt ggctcattat
    19741 ccagaaagtc tacaacgact tttccaaagt agggactttt caataaacgt tcgatctttg
    19801 ctagctgatt ttctgcgttt ttctgtttga tattcatctg atcgatttct ctatttttca
    19861 tttcaatcat cgaaaaagta tccaggttat ctaagtaact gtcaaaattc aatcgaagct
    19921 cgccagccat ttctttcaac gactggtttc cttctatttt tgccgtatcc atcgattccc
    19981 gcagttcgtt ttttttatca attagctttt gatacacgtt cttcagatat gcttcttcta
    20041 actgtttttg tgtgttgacc atacacattc tcctcttttt ttaaagtggt ggaaccgatt
    20101 agtttacctc ttttaagagt cgaatgcaag ctttttaacg agtatcattt gttaggatat
    20161 atcagttctt caggtcggac agtttgatat aaagaaaatg caccatcaag gttttttacg
    20221 tggtagccag actgcttcaa gattctttcc gctagatagc tacgtaatcc gctatgacag
    20281 ctgacgatat attcttgttg gctgtctaat tcatttaatc ggtcccgaag ttcattcaaa
    20341 gggatatgtt tggcttcctt gaatttgccc ttttccaatt cttctgctgt tcgcacatct
    20401 aataaaattt ttccttttgc tagttctgtc ggcaattcat gccattgtac ggtttcacta
    20461 agcccttctg caatgttcat tgctgcatat cctagcatgt ttactggatc tttggctgag
    20521 ccaaatggcg gtgcatacgt caattctaat tccggtaaat cgaagatcgt caaatgccct
    20581 ttgattgctg ttgctaaaat atcgatccgt ttatccacac cttttgcccc aacaccttgt
    20641 gcaccataaa tctcgccagt ctctggatgg aagatcaact tcagtaaaat atctgttgct
    20701 tctggataat agcttgcatg atcttttcct gatacatgaa tgacttcaaa agacagttcg
    20761 ttttctttgg ctgttctttc acttaaaccg gtggatgcgg cagtcattcc aaacgttcgt
    20821 ataattgctg ttccaatacc gccttgattt cttcgagaaa ttccggaaat cgtgtccgca
    20881 acttgtctac cttgacgatt ggctggtgaa gcaagagaaa taagtgcatc ttttccagtg
    20941 atttgctgtt ttacaacgat agcatccccc accgcataaa tatcaggaat attcgtttga
    21001 taacgttcgt ctactaggat acccccgcgt atgcctaatt cgattccagc ggtcactgct
    21061 agctggttat caggacgaac accaatggat aaaataacta aatcagcagg gatggtacgc
    21121 ccatcatcca gtcgcaatcg tttcccgtgg tcttcaaatc cagcgacagc atgagaagta
    21181 atcacttcta ctccttgatg agacaattct ttttctataa aagctgccat ttcttcatcc
    21241 agtgttggaa gaatatgtgg tgcttgttcg atcaccatga cttctaaacc tcttcttttt
    21301 aggttttctg ccatttccaa tccgatgaat cctgcaccaa cgatcacggc acgctttggc
    21361 tgtttttcta atgcatgcat cactttatcg atatctggta catttctaat agaaaaaaca
    21421 ttgtcggctt ctgttatccc tggaatcgat ggaacaactg gttttgcacc aggagataaa
    21481 accaatgcat cgtactgttc aatgtgtttt tgaccctcat gtacgacttc taccgttttg
    21541 ttttcgggaa agatggctgt cacttcatga tttggacgca catctaaaca aaaacgagcg
    21601 gataatgatt ctggcgtttg gacaagaaga ttttcccgtt cactgatttc tcccgaaaga
    21661 taataaggca agccgcaatt tgcaaaagaa acatacggtc ctttttcaaa aacaacgatt
    21721 tctgcatctt ccattaatcg gcgaagccgt gtagcagcag acattccacc tgctacacct
    21781 ccgacaataa cgattttcat cttatttccc tcctactgtt cgatcaaacc attgattcat
    21841 gccaccacgt acattcacta catcataacc agatttcttt aattctttag ctgcttgttt
    21901 actcctcatc cctgattgac aaatcacata gacggtcttt tctttgtctc catcatatct
    21961 gtttatactt tgtaatggaa catttttagc tccttttata tgcccgcccc ggtattctgc
    22021 aggtgttcta acatcaagta acgctggatt ttccaaaagc ttttccttta attctgggac
    22081 tgttatcgat tttattgatt gaaatagcaa attcattttc tgcacctcat ttacattttt
    22141 ataaatacct catggggtat attaaacagg agctttatta atatgtcaac cagaatgact
    22201 cttcattttt ttcactactt tttatatttg cataaaatac cgataagggg tattatctaa
    22261 ttataaaaat agaggagaat gtgttatgga gattgataat aaaaatatcc tgaaccgttt
    22321 gaaacgtaca gagggacaaa ttcgtggtat ccaaaaaatg atcgaagacg aaaaagaatg
    22381 tatggatgtc atcactcaat taagcgctgt tcgttctagt attgatcgcg taatgggcat
    22441 gatcgttgca gataatctga aaaattgctt tgagaaacct gatagtaatc cagaagaaca
    22501 agcggctaaa ctagaacaag cgatcaagat gattattaaa aagtaaagga atgatttcaa
    22561 tgaaagtcgt tttccatatt gatgaattag aaaaatggtc agaaacaggg aaaaacgtaa
    22621 aaaacctgat aaaagcttct ccagaaacga cgattgtcgt atctgtaaat ggcatcgcga
    22681 ttaccggtta tctagactct gccaatgcag aattcttaga tttgcaagga gtcgtttttc
    22741 acgcttgcgc caatgctatg cgtgctaatc atatttcaga aagttcttta cctgaacaag
    22801 taatcgttgt accagcaggt gtccttgatt tagttgaact gcaatcccaa ggttatgctt
    22861 atatcaagcc ttagtcagta gaggttgcga cagaagtgat cagcttcaag aaatttcggc
    22921 ttatttttcg aagaagctac ttctggaaaa ccgtgaatca aaggttgtga aaacgctgtc
    22981 ctgcatcaag t
//
LOCUS       DACGLI010000049        22298 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.050, whole genome shotgun sequence.
ACCESSION   DACGLI010000049 DACGLI010000000
VERSION     DACGLI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.050"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            2..400
                     /locus_tag="IXT22_002100"
     CDS             2..400
                     /locus_tag="IXT22_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4863436.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="IXT22_002101"
     CDS             384..1079
                     /locus_tag="IXT22_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAQ4863437.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1673..2560)
                     /locus_tag="IXT22_002102"
     CDS             complement(1673..2560)
                     /locus_tag="IXT22_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAQ4863438.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEGAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2745..3584
                     /locus_tag="IXT22_002103"
     CDS             2745..3584
                     /locus_tag="IXT22_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4863439.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3780..4754
                     /gene="sgrA"
                     /locus_tag="IXT22_002104"
     CDS             3780..4754
                     /gene="sgrA"
                     /locus_tag="IXT22_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAQ4863440.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5052..5408
                     /locus_tag="IXT22_002105"
     CDS             5052..5408
                     /locus_tag="IXT22_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863441.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5411..6568
                     /locus_tag="IXT22_002106"
     CDS             5411..6568
                     /locus_tag="IXT22_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863442.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6594..7034)
                     /locus_tag="IXT22_002107"
     CDS             complement(6594..7034)
                     /locus_tag="IXT22_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4863443.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7194..7700
                     /locus_tag="IXT22_002108"
     CDS             7194..7700
                     /locus_tag="IXT22_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4863444.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7868..9781
                     /locus_tag="IXT22_002109"
     CDS             7868..9781
                     /locus_tag="IXT22_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4863445.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9786..10787
                     /locus_tag="IXT22_002110"
     CDS             9786..10787
                     /locus_tag="IXT22_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863446.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10989..11195)
                     /locus_tag="IXT22_002111"
     CDS             complement(10989..11195)
                     /locus_tag="IXT22_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAQ4863447.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11841..12689)
                     /locus_tag="IXT22_002112"
     CDS             complement(11841..12689)
                     /locus_tag="IXT22_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4863448.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12853..13755
                     /gene="gnd"
                     /locus_tag="IXT22_002113"
     CDS             12853..13755
                     /gene="gnd"
                     /locus_tag="IXT22_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAQ4863449.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKRTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13757..14758
                     /locus_tag="IXT22_002114"
     CDS             13757..14758
                     /locus_tag="IXT22_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4863450.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14755..15039
                     /locus_tag="IXT22_002115"
     CDS             14755..15039
                     /locus_tag="IXT22_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4863451.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15072..15869
                     /locus_tag="IXT22_002116"
     CDS             15072..15869
                     /locus_tag="IXT22_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4863452.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15883..16716
                     /locus_tag="IXT22_002117"
     CDS             15883..16716
                     /locus_tag="IXT22_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863453.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16734..17591
                     /locus_tag="IXT22_002118"
     CDS             16734..17591
                     /locus_tag="IXT22_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4863454.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17613..18122
                     /locus_tag="IXT22_002119"
     CDS             17613..18122
                     /locus_tag="IXT22_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863455.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18159..18560
                     /locus_tag="IXT22_002120"
     CDS             18159..18560
                     /locus_tag="IXT22_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863456.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18672..19025
                     /locus_tag="IXT22_002121"
     CDS             18672..19025
                     /locus_tag="IXT22_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863457.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19059..19502
                     /locus_tag="IXT22_002122"
     CDS             19059..19502
                     /locus_tag="IXT22_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4863458.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19519..20604
                     /gene="uxuA"
                     /locus_tag="IXT22_002123"
     CDS             19519..20604
                     /gene="uxuA"
                     /locus_tag="IXT22_002123"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4863459.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20597..21310
                     /locus_tag="IXT22_002124"
     CDS             20597..21310
                     /locus_tag="IXT22_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4863460.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            22062..22262
                     /locus_tag="IXT22_002125"
     CDS             22062..22262
                     /locus_tag="IXT22_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4863461.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7680 a         3430 c         4619 g         6569 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat
     1561 aaaaaaaggc cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt
     1621 tccaaaaatc acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga
     1681 atatattttt tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga
     1741 ttgttttatc catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct
     1801 cagatttgta tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat
     1861 aatagctttg ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt
     1921 tttttagttt aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa
     1981 aattcatttt tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct
     2041 tggagaaatt ttctccttca tttgcttctt tttttgcttt atctgctcct tctttagtcg
     2101 aaaatagaat gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat
     2161 ctttatctgt taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa
     2221 agagtttctt atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg
     2281 gaccgagttt tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt
     2341 ttccgtatac atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat
     2401 ttgatttaac ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg
     2461 ttgcaatcgt ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa
     2521 ggcacataat tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag
     2581 tctaacagaa gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt
     2641 agttcgtaaa aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa
     2701 gaaagaaaag ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc
     2761 ggttgattgg atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata
     2821 atgcacttgc ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg
     2881 tcggacattt agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa
     2941 gaatagaaga ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc
     3001 tcgttgttgg aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt
     3061 atcggttaga ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta
     3121 ttgcagtggg ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta
     3181 gatttggtcc gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat
     3241 tgaatcctaa catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca
     3301 gcgcacttat ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga
     3361 atcggacaca aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt
     3421 tctccactct gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag
     3481 catctatatc aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat
     3541 ataaaacaaa gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa
     3601 ggctgatatc ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat
     3661 tcaagcgaat acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca
     3721 ttttcatttt atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa
     3781 tgaagaaaac agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga
     3841 ttggaatcag tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa
     3901 ctgatcggat tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca
     3961 aaagcgtgaa tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa
     4021 gttcagaaaa agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg
     4081 agtatacaat aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag
     4141 ttgatttgat tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca
     4201 gttggacagt tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag
     4261 aaaacacgag cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca
     4321 cgagcagcga aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca
     4381 gcgaaagcag tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga
     4441 gtagcacagg aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt
     4501 tggtacctat cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg
     4561 tgctaaaaca gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa
     4621 cagataatag aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta
     4681 catggatggg tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc
     4741 atcgagtgaa ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt
     4801 gagtgaatat ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc
     4861 tatttttgtt tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata
     4921 agagcaagaa taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac
     4981 gaatctattt gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag
     5041 gagtatgtac tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt
     5101 tgaactattg ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc
     5161 taaactacac cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa
     5221 ggtatccaga atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt
     5281 cttctcagtt tttactgagt aaagtttatt ctatactttt agagggaacg attggttata
     5341 ttttactgga ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa
     5401 ttatataagt ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa
     5461 ctatcattta tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat
     5521 ccgatacttt tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt
     5581 atcaagtata aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac
     5641 gcgtagtata gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa
     5701 acaaggccac tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat
     5761 aacaaaagaa gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc
     5821 gatgaatcac atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa
     5881 cacctatttg gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg
     5941 gattgaatcg tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc
     6001 agaaaaaaat tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg
     6061 gacaaaaaag aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat
     6121 atttccagtg atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc
     6181 agagcttaat acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt
     6241 cagggatatt tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg
     6301 taaaacacag gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa
     6361 atatagtgca tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa
     6421 aaaggcatat gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa
     6481 tgattgggcg cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat
     6541 attggaaaaa ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac
     6601 attgcaaaaa gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg
     6661 agctcttgct ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca
     6721 gtcaaaagtt ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta
     6781 cgaatctcaa tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta
     6841 taactaatag aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag
     6901 tggataaatt catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata
     6961 tcatggacga taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac
     7021 aatttaatca tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa
     7081 atagtcgaaa agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa
     7141 ctagctagat aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa
     7201 acacagccga cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc
     7261 cgatacacga attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa
     7321 cgattgggaa accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa
     7381 aaccatggga gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa
     7441 cccatgcgaa ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc
     7501 attcgatcga attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg
     7561 ctcatggatt aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc
     7621 cttttatgaa agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc
     7681 tgacattttt ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt
     7741 tatccattct gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata
     7801 aaccatttat tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata
     7861 aaaaggagtg aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt
     7921 tgctgtaagt acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc
     7981 ggaatctcgg gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag
     8041 tacttcacaa acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga
     8101 tcaagaaacg accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat
     8161 gtcaaacgac gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga
     8221 tgatatcggt aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca
     8281 gatgacagaa atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt
     8341 agtcactgag cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat
     8401 tgctacttat ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct
     8461 tggaggtaca gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa
     8521 acaacttcat caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata
     8581 ttatgtcgat caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg
     8641 gaataacggg atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt
     8701 atttgttgat tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata
     8761 tgagtcagat gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa
     8821 gattttactt tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga
     8881 tattcctgtc aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca
     8941 actacgtttt acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca
     9001 gttagacatc attggggatc aagagcatga agatttattt atgggccttt tgaaacaata
     9061 ctattttgat caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc
     9121 agattcattg cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa
     9181 cgcgcaaaaa ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc
     9241 agggcatgga aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt
     9301 tttgaaagta gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag
     9361 tctactcaaa gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac
     9421 agagcaaaag acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat
     9481 ttttaatgag acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc
     9541 aaaaaagcaa gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga
     9601 tcaatcaagt gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga
     9661 tgcaaaaaaa agaatgttgc cgaaaactgg agaaaagaaa cattcgcttc tcatttattc
     9721 aggtggattt ttatctgtta gcacgattat cacatggatt tggcgaagaa agagagggta
     9781 aatgaatgaa atggttcaag cgaatagtga ttgcagtacc agttatcatc gtagttattt
     9841 tagtcactgt atttttgatt aatcaaatca caccaaagcc gattagcttg cttgttagaa
     9901 aacaatttga cacaagtgaa aaagaacaag tatatgcccg accagatgat ttccagcaaa
     9961 aaatcgaaca aatcgatata aaaaaagaaa tatcctatcc ttcaaagtac aaaaataata
    10021 atatggatat ctacacaccg aaagtggaaa agaaaaaatt accgattctt ttctggatgc
    10081 atggaggcgc atatgtagga ggggataaaa atgattgtcg tgattatttg gaatatctat
    10141 gttcagacac gcagcaaatc atcgtaaata tagattatga acgatcaccg gaagcaaaac
    10201 atcctacacc agttatccaa ttgaacgaag ccattcaagc agctaaaaaa gagataaaag
    10261 atcaagcaga ttggtcgaat atttcgattg gtggaaattc ggcaggtgca caaattagtg
    10321 gagaatattt gttagcactt caaaatgaag aaattaaaaa agctgatcat cttgatccga
    10381 ctttggagaa caagcagatt acgaagttta tttctttgtc tggtctgttg gatccttctg
    10441 cacttactca agtaagtgat aaaatctcta gctttcttta tgaaaaatgt ggatgggctt
    10501 actttgataa taaggacttt gaacaatcag agaaggtcaa aagtttagcc ttggtcagac
    10561 atgcggatcg ttggacgcaa aacacattct taacggatgg aaatacaaat acgtttacga
    10621 aacaaatgga agaagtaact tctgtatttg agaaagcggg ggtgaaagtc acaaaagtag
    10681 attatgcgga gaaaaatgct gttttgaacc atgaatatca gtttgatttc agcaataaac
    10741 aagcgcaaga aacatatcaa aagttagtaa tgtttttcaa ggagtaaagt cttatgatgc
    10801 aaaagaggtt gtaatctgtc acttagctcc aagtcacaag gagcaatttc aataaacaag
    10861 cttttcatgg tttatgaata ttgtaacttg tgactgagga gttagagatg gcaaggggca
    10921 ccttttattc gaaatttggg aatatcacac gattattgtc acgatctctt ttacgtaaat
    10981 tttataagtc agatttgttg ttttgatcgt ttaaaaaaag caacaaatcc gaagcctgcg
    11041 gaggcaagaa gggacaaaaa gccgagtggt aagcaaaaga atgctggttc cactaatatt
    11101 ccgttgttat tgatataagg ctgggaacaa agatgaatag caaataaaat caatgcacta
    11161 gcgaaaaaaa gcaaagaaat atggatagct ttcataagca gcacctcctt ttttataatt
    11221 gtatgataaa tagattaaga atctataaat gtgacaagtt tgttaggatg tgaataaaat
    11281 gatcatctag cgaacttgaa acaaagatgg ctaatgataa gcaattaatg attcagcaat
    11341 cagataggta caaagtttac catcatacgt ctagaccaat aatagaaaat atgggaatat
    11401 aatagaaaag atttaggata cccccaaaag aatttcccca aaaattcgat gtatcctaaa
    11461 cttttttatt ttacataaca atcatatcaa ctgtgaaata aaattacaaa tgataaccta
    11521 aaatgaggcc aaaagccagt gttatcaagg aaatacttaa ttcaccaaaa ttttttttaa
    11581 ttttttagaa aataagaaac aaaaataata aaaaaaagaa aagataaatt ttttactact
    11641 gtatactaac tttgttatcg catctaacaa gtaactcgaa taataccaat acaaccttct
    11701 ccaaagatgc gatgacatac gttctaaccc accgactatt gatgttctgt accacccttg
    11761 cagaaccaaa aaagccacta ccaaatattt ggtagtggct ttttttgttt tatggatttt
    11821 tcgctttttc tgttatggtg ctattctttg atttcagaaa tagtatgtcg aactttagcg
    11881 atagaacgac gtgattcttt ttcgttgtaa aacatcaaaa tcacatatag agagtccaaa
    11941 atgcttagtt gagaaatacg ggaagctaaa gcttcagatc ggaattctgt ttcttcagaa
    12001 atagaaataa aaacgacatc gccaagttta gcaagggaag aattagcttg gctagtaata
    12061 acgattgttt ttgctccagt ttttcttacg gtttcagcaa tatggattgt ttcttttgat
    12121 tgccctgtgt gagaaatcaa aacagcacag tctttttccg tcaataaaga agcttccatc
    12181 aattgaatat ggtaatccgt gctgtgagaa gttgcgatag gggaacgcaa aaatttatga
    12241 taagcgtcag ttgctacaat ctctgaaccg ccaacaccga aaaaatagac acgtttagat
    12301 tcattgataa tagtagccgc tttttttaga tccttttgtt gtaacaactt ttttgtgtca
    12361 tttaaagttg aaatactaga ctcgaacacc ttttgcgcca tagtgagctc agtatctgtt
    12421 ttctgaatat tttcgtggat agaaatagca gatagatcat tttcttggat caacatggcc
    12481 attttaaaat ctttaaatcc attataacca agtttttttg taaattgaaa aaaagtagag
    12541 tcagcaatgc ccagttcact tgctaaattg ctaataggac tatgacttac tttgcttgga
    12601 ttttctaaaa tataatcggc gatagcctgt tcttttgggc tgaagtcgtt gtacattgtt
    12661 ttgatttgta gtcttatgga gacgctcatg agaattcctc attttcataa taagattatc
    12721 attttttccg ttctcattaa tgttaaagat acaaggagag taggaaaaaa tcaaacaaaa
    12781 aatatttttg taaaatctat ttacaaaaaa atttttttgt ataatgaggg tataagaaat
    12841 ggaggcgcta tcatggaaat tggtgtaatt ggtttgggaa aaatgggatt gaatttagct
    12901 ttaaacttaa aagagcacca tcacaaagta caaggactcg acatttcaag tacagctgtt
    12961 agtcaggcaa gagaaaatga cattcctgct tatcaagaga tctctgaatt tctagctact
    13021 tttgagcaga aaaaaatcat ctggttaatg cttcctgctg gagagataac cgaaaacatg
    13081 ttaagaaaac tttttccaaa actcggacca ggagacatta ttattgaagg cggaaactct
    13141 tattataaag attcaatccg tcgagcagaa gagtttcaga aaaatgaaat cggttacttg
    13201 gattgtggga cttctggagg aatcgaagga gcacgacatc aagcctgctt aatgattgga
    13261 ggagataaag aaacttttct atccgtggaa caattattca aagatgtagc aattgaaaga
    13321 ggatatctgt atgctggtgc atccggaagc ggacacttct tgaaaatgat ccataatgga
    13381 atcgaatatg gaatgatgca agcaatcggt gaaggattcc aacttgtaca aaaaagtgag
    13441 tatgcttttg acttggaaca agtcgcacgt gtttggaatc atggttcggt gattcgcggc
    13501 tggctgatgg aaatcatgga agatcagtta aacgaacatc ccaatttaag taattatcgg
    13561 ggaatcgttt ctgcatcagg tgaagcaaaa cggacggttg aaacagcgct agaaatggct
    13621 gttccagttc cagtaattgc aactagtttg ttcatgagga atctttcaca ggaagaagat
    13681 agtttttcag caaaagtagt ttcagcacta agaaatgggt ttggcggaca tgaaatagtt
    13741 gaaaagggtg agtaaaatgc cagattatca tatagcaatc gttaattcca gcagtttcgg
    13801 aagagtcttt ccacaccact tggaaagatt aaagtcagtt ggagacgttc atttctttac
    13861 tgttgatcaa gagattccag gaaaagaact agcggagtta cttaaaggat tcaatatcat
    13921 tattgcaagt gttacgccat tttttcgacg agattttttt gaaaacaaag atgaactgct
    13981 attgatttcc cgacatggta ttggttacaa caatattgat ttaaaagcag caaaagaaca
    14041 ccagacaatc gtatctatca tacctgcttt agttgaacga aatgctgtag cagaaaataa
    14101 tataactaat ttgttgtcca tgcttcgacg cacgacacaa gcacaagcaa gagtcaagga
    14161 cgatcgatgg gaagatcggg cggagttcgt cggtaggacg ctgtttaaca aaacagttgg
    14221 tgtgattggt gcaggaaata ccggaagcgg agtaatcgaa attttgcgta acggttttcg
    14281 ctgtgatgtt ctagcttatg atccttacaa atcagattta tacatcgaaa gctttggtgc
    14341 aaaaaaagta gaacttcaag aattactgga acaatcagat atcatttgtt tatgtgcgaa
    14401 tttgacagaa gagaactatc acatgatttc tgataaagaa gtcgatcaga tgaaagaaaa
    14461 tgtttatcta tctaatagtg caagaggcgc tctagttgat gaagaagcga tgattaatgg
    14521 tctgaaaagc ggaaagatcg caggatatgc cacagatgtt ttagaagaag aaccgggacg
    14581 tcaagatcat ccgtatttag cgtttgaaca agtagtgatt acgccacata tatcggccta
    14641 cacaagggaa tgtttagaag caatgggtga aaaatgtgtc agagatgtcg aacagatcag
    14701 tcagcacctt cttcctgaac gttctgtcca gacaaagagc aactatataa aaggatgatg
    14761 aagaaaatgg tgaacggttt aaaagtgaaa acaggccctc aattttattt atatgaagaa
    14821 ggtggtattt caaaagtttc tgatctcttg aaatcatacg gcgcgaaaag agtactggtc
    14881 acccacggaa cggtatcatg ggaaaaggcg ctacctaaat tagtattttt gaatgacgaa
    14941 acgattcaat ttttttatca tcgttattct ggagaatgta gttatgctga agccagacga
    15001 atagctacaa tcatcaaaaa aatgaaatcg atttcgtagt tggcgttggc ggaggaaaac
    15061 tgaccgatct agtgggttat agtgccaatc ttgcaagaat cgatttcgga gtcatcccta
    15121 ctttagctag taattgtgct ccatggacac ctcttgctgt catgtataag gagaatggac
    15181 aagcagaagg gaaaacagaa cacttttaca gacaagctgc tttttttata acagatcccc
    15241 aattagtgat tgattcccct gttccatatt tcattgccgg gttagcagat acactagcaa
    15301 aatggtatga atctgagctc atcttagaac aagatttttt gcaagatgaa tcatttttga
    15361 agctagcaca agatactgcg aagatctgca aagaagagat tttgaatcat tctgctaaag
    15421 caatccaaga tatggcacaa agaaaactga catcggagtt caaacagctt tcagagatta
    15481 tctttgctgt tgctggttta gttggaggat taggagataa atacgcaaga aatgtggcag
    15541 cacatgctat gcatgacgct atcagtaaat atattccgga aagccatcgt tttctacatg
    15601 gagaaaaagt agcgtatggg attttctatc aactggcact agaaggtcgc tgggaaaaaa
    15661 tagacgagtt atatcctttg tatcgggaat tagaactgcc ggtttctcta gaacaaatgg
    15721 gattatttcc gaaagataaa cagataatag ataaaatggc tgaatttatt gattcgaaag
    15781 agaaagtgca tttgattcct atagaggtaa cacagaaatc actgatacag tcaatgatgg
    15841 aactggaagg ttatatcaga aagatctgaa ggaggaggac acatggaaac attaagtgta
    15901 gtacaaagtt tgttgattgc tttatgggta gccgcggtta tgtcccgctg gttaggtgga
    15961 ggagccacgt tgaccttacg tttttctcct ttgatgactg gattagtcgt cgggttgatc
    16021 atgggggaag ttgcacaagc gatgattgtt acagccgctt tgcaaatgat ttatatgggg
    16081 gttttttctc caggaggatc aatgccagct gaaccatcta ttgcagcagc tatcgcagta
    16141 ccagtcgcat tattagggga tctgtcgcca gaagcagcga ttgccgttgc ggtgccagtc
    16201 ggattgctcg gaagttactt gtatcagttt cgttttttca tcaatacttt tttaggtaaa
    16261 tatacagaca aagctgtaga agatttgaat acaaaagcta tggcccgatc aattattctt
    16321 tatccaacgg ttgcctcatt tttattattc gttccgcttg ttttcattgc tttatattta
    16381 ggggcgccat tgatcgctga tgtaatcaaa gctttagagg gaacagtcgt tatccacatt
    16441 cttgaagtag taggtggagg gttagcggca atcggtatcg cgacaactgt atacgttatc
    16501 ggtcgaaaag attatctggt ctttttcttc cttgcttatt ttatgagtgt tgttttgaaa
    16561 tctttagata ttacgatggt tacttatgcc atttttggga ttattatcgc tttgatcttt
    16621 gtccagtcgc aaaaagggaa acaagtacag cctgccacaa gcaataacaa ttcagcatct
    16681 tttgatgacg aagatgacta tgatgacgga ttttaattta ggaggaatgg gaaatggctg
    16741 aaataatgga taatcaaaca ggtgctcctg aagaaatcac gaaaaaagat gtaacaaaag
    16801 cctatctgag atggcatttt gcaaacgaaa ttcctcactc ttttgaacgt tacttggcgc
    16861 catcactact atacggaatg atgccaatct tgaaaaaact ttataaagat gaagactctt
    16921 taaaagcagc atataaacgg cagttactgt tcttcaacac tcaattaagc tggggtggcg
    16981 gtgtgattac tggcctaatg tcttctatgg aacagcaaag agcagaagaa gagtatgaag
    17041 aaaaagagat cttgatgcag gatgacttga tgtataacac gaaagcggga ttgatggggg
    17101 cactagcagg aatcggagat gcaatcgatt caggaaccgt ccaatatatt tttatcgcaa
    17161 tcgcggtacc ttgggcacaa cagggaagtc ctttaggcgc actttttcct tttatctgct
    17221 ttgggttgta tcaggtttta ctaggggtat ttttcgcaag acaagctttc actatgggcc
    17281 gtaatgctac aggcctaaag caaaacactg gtgttcagac agcgattgaa atgctatcag
    17341 ttttagggtt gtttatgatg ggggtgcttg cgggaaacta tgtaaaagta gaatcttcat
    17401 tgaaatttgc gatatccgga cgtgagtttg ttatccagga aattcttgat caaatcgtgc
    17461 cagggatatt acctttagct gtcgtaatgg gtgtgtactt gttctatacg aaaaaaggat
    17521 tgaaagtcac acaagcatta ttatggctga ctggaatatt aattgtgcta gcaggaatcg
    17581 gtattttata aaaagaaggg aacgtgaata agatgggtgt agtcaattta gcgcgtgtgg
    17641 atgagcgttt gatccatggg caagtaatgg taacgttatc tcaaaaaagt ggagtgaatt
    17701 ccatttttgt tgtagacgaa gttgtagcaa aagataaatt tatgagagat ctttacaaaa
    17761 atgcaggaag ccgtacagga caaaaaacaa ttgtcattac accagagaaa gctaaattct
    17821 attgggatga atatcaattt aaagaataca attgtatttt gatcgcaaaa acagtccaaa
    17881 cgatttacga cttagtaaaa cacggaatcc ccatggaaga attgaatatt ggagggattg
    17941 ctcaaaaaaa tcctgataca gatcttttag tgacgaaatc tgtttattta aataaatcag
    18001 atgctgaaaa attgaaagaa atgaatgaac aatatggcgt aaagaatatt tattttcaag
    18061 ccactccatc tgcacctaaa acaggattaa aagatgtatt gaacaagttt gatttgtcat
    18121 aaacaaatgc ttagaaaaaa gataaagagg gcgaaaaaat gaagaagaac gagctgtttc
    18181 gtgattggga atttcgttat cgctatattt accgtaagcg ccgtacaaaa aagagtaaac
    18241 agcgttttct ttcagcatta gtatcagata tttacagtat gagaacagat gtgacagtca
    18301 ttgcttacga tacgctagcc taccgatcaa aaaatattta tgttggagat atcgaaaaag
    18361 cagagaaagt tatctgtact tattacgata cacccgttca tgcattagga agttatttca
    18421 tgtttgattg gaaagaccaa aggaaaaaaa caatctactc tatattattg tccttcattt
    18481 tgttgttcag tttaggttgg tggggaatga tgatatataa caaaaatcct catcacgtat
    18541 tcgatctgct atccgtataa acaggtatca ctgtactagc atttgggagc tactttttct
    18601 tattgggaaa agcagctcgc ggatggccta gcagacaaac ttttattcga aatacttcat
    18661 ccatattaac gatgctagaa atgatccgta cgattgatga tccgagtgta gcgtatgcgt
    18721 ttgttgatga aggctgttat ggagaaaagg gcttagacag cgtgagatcg ggtatgaaaa
    18781 aagaggctat tcttttttat ctagactctg ttggggcaga tacaccgcta cagttttcgg
    18841 gaaattattt ttcaaataaa gaacagtggc tgaaacaagt tgataagttg aaagaaaaaa
    18901 acgtcaatta tatttttagt gcaagaaaaa agcaagcgca gttcttctat ttgaccaaaa
    18961 cagatttacg agggaaaaca tttaattggc aaaatgccaa tcagattatt gctctttttc
    19021 gataagtaaa aagtgcaaaa caaggagtga gaagactaat gttggaaatc atgatcgtta
    19081 cacatggtaa gttgagcgaa ggactgaaag atgcggcgga agtaattgtc gggacatcga
    19141 gccatattga aacaatgtgc ttagagtctg gggaggacat ccaaacattc ggagagaagg
    19201 tcaaagaaaa attaactatg atcaacacag cagaacccat gctagtattt gttgatctaa
    19261 ttagcgcaag tccgtacaat caagcgctct tggcagtcaa tgaactgact gaagaaaaga
    19321 aagcagccac ttatgtcata gggggcgtga atctgccaat gttgttagaa gcaatcaatc
    19381 atcagatgct tcacacaccg atagaagaag cggtggaaca aattgtcaaa caaggaaaag
    19441 ataatttaac tgtttggcat gcttcagcgg aagaaaaaaa attagatgag gacgattttt
    19501 agaaggaagg ctgaaaagat gaagtgggga tttagatggt atggtgaaaa aggggattcg
    19561 atcccattaa aatatgttcg ccaaataccg ggaataaatg ggataattgg aactttgctg
    19621 actaaaatgc ctggagatgt ttgggagatt tcagaaattg aggagttgaa agcatctgtt
    19681 gagagccaag gactggaact gcttggaatt gaaagtgtag cgatccacga tgcaatcaag
    19741 gcagggacag atgaacgaga ttactatatt gataactata tacgaacaat caaaaacttg
    19801 tctcgatgtg gggttcgatt gatttgttat agcttcaaac caatttttgg atgggcgaaa
    19861 actgatttgt ttaatgaaaa caacgatgga agctattctc ttttatacga tcagaaaatc
    19921 gtcgatcaga tggagccagg agaaatgtat caattgatac acagccagtc aaagggattc
    19981 aaattgccgg gttgggaaga agaacggttg aaaaaattcg ctcagctgga aaaactgtat
    20041 gaaggaatga ccgaagaaga attatttgaa aatctgactt attttttaga aaaagtgatt
    20101 ccagtgtgcg aaaaagcaga tgtaaaaatg gctatccatc cagatgatcc gccatgggaa
    20161 ctttttggtt ttcctagagt gacgaaaaat cttggcgact tgaagaaaat tctaaatgca
    20221 gtagattctc catataatgg actaacgctg tgcacaggat ctttaggggc aaatccggaa
    20281 aacgatttag ttgaaatcat ccatgaggta ggttcgcgca tccattttgt ccacttcaga
    20341 aacgtggagt ttttaggaga aagaaagttc aaagaaacgg cacatccctc tacagaaggc
    20401 tcccttgata tgtatcatat tatgaaagcg ttggtgcaag aagggttcga cggtcctata
    20461 cgccctgatc atggtagaac cgtgtggggt gaagtggcta tgcctggata tggcctgtat
    20521 gatcgtgcaa tgggactcac ttacatgcaa ggtctatatg aggcgataag taaggaaaaa
    20581 ccactgggag agcattatga ataaaatcaa gctcttcatc tttgatatgg atggcctttt
    20641 attagaaact ggacgtttag cttatcgtgc ttatgtaaaa tcagcacaaa agtatgatta
    20701 tgaaatgcgt aaggaagtct attatttact aactggccaa acagaaatgg cgataagaga
    20761 acaaatgggc attttgtacg gagaagatgt tccatatatc aaatggcgag aagcaatcaa
    20821 tcaatataaa gaaaaaatcg tgaaagaaga taagagagta tatacgaaaa aaggagcaga
    20881 agaaatttta tcttttgcaa aagaaagagg aatccataca atcgtggctt cgtctaatac
    20941 acgggtaaaa gtagaaatgt atttaaaaat ggaaaatcta tatgccttgt ttgatcaaat
    21001 catttcaggg gatgatgtaa aaaaaggaaa gccggaacca gagatctttt tgaaagcttg
    21061 ttcaaaaatg aatattcctc caagtgaagc acttgtattt gaagactcga ttgcagggat
    21121 cgaagcagca aggcgagcgg gcattttgtc ttttctcatc aaagatcatt tgatagggtt
    21181 gcccgatcat aatgggaagc ataagttgaa agtagatgta agtttatatg aatccaataa
    21241 agcagactat gaattttatg acctgcatca agcaaaacga tttttagaaa gtaaagggtt
    21301 gtatctctaa taaagaggac tattttctag tcctctttat ttattgtcct gcacgactga
    21361 gggaacagat gaaaaagaag taatttttta ttttgaagta tctaccttat ttgtagtgaa
    21421 caatttagaa caaacacaaa acgcatctac tgttatctac cagtagatgc gtttaaagag
    21481 aagaacgaga atcgtccata tgagggtttc cactccttat gcagattttt ttaattcttg
    21541 cactgcttgt tcgatcgtaa cacctgtcgc tacatgattg gtattttctt tgtcaaaaac
    21601 gacaaataga ttcaaatctg tatccaaggt tactcgatat tgtatatctt tgttatagaa
    21661 tgtcatagcc attctccttt ctttaaatac ttgctgaaag gcaacgaacg cgttgataac
    21721 gaaattccat ttataagtat accaccaatt gaaaggtttt catagttaag aaattttaaa
    21781 gtcaaaagtt gcagataaaa gcaaataaac aagaaaacaa aaagtgaatc aatcgcggtt
    21841 attcaacttt ttcttcgatt cgaagacaat agaagacaat gaattttata tttcattgca
    21901 ttatccttgt gttattagaa aaagcatgat atattaaatg agtaatctat tttgaaacgt
    21961 aatttgagcg atatatctac atagataaaa ctccttttgc ctatcaaata tttattgcaa
    22021 cgaaaaaacg tacattgata cgtatcagga ggaatttatt tatgaataac ggtacagtaa
    22081 aatggttcaa cgcagacaaa ggttttggct ttatcactgg tgaagatgga aatgatgtat
    22141 ttgcacattt ttcagctatc caaggtgacg gcttcaaaac tttagaagaa ggccaagcag
    22201 tgtcttacga tgttgaagat ggtcaacgtg gccctcaagc aacaaacatt gttaaagctt
    22261 aataaaaatt gacttttaac cgtcttttcg aaagaaaa
//
LOCUS       DACGLI010000050        22024 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.051, whole genome shotgun sequence.
ACCESSION   DACGLI010000050 DACGLI010000000
VERSION     DACGLI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.051"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(59..1369)
                     /locus_tag="IXT22_002126"
     CDS             complement(59..1369)
                     /locus_tag="IXT22_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4863462.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1381..2799)
                     /locus_tag="IXT22_002127"
     CDS             complement(1381..2799)
                     /locus_tag="IXT22_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863463.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3039..4607)
                     /locus_tag="IXT22_002128"
     CDS             complement(3039..4607)
                     /locus_tag="IXT22_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAQ4863464.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4611..4892)
                     /locus_tag="IXT22_002129"
     CDS             complement(4611..4892)
                     /locus_tag="IXT22_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4863465.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4889..5812)
                     /locus_tag="IXT22_002130"
     CDS             complement(4889..5812)
                     /locus_tag="IXT22_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAQ4863466.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5809..6687)
                     /locus_tag="IXT22_002131"
     CDS             complement(5809..6687)
                     /locus_tag="IXT22_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4863467.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6674..8011)
                     /locus_tag="IXT22_002132"
     CDS             complement(6674..8011)
                     /locus_tag="IXT22_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4863468.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8014..9117)
                     /locus_tag="IXT22_002133"
     CDS             complement(8014..9117)
                     /locus_tag="IXT22_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4863469.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9191..10699)
                     /locus_tag="IXT22_002134"
     CDS             complement(9191..10699)
                     /locus_tag="IXT22_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4863470.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10665..11357)
                     /locus_tag="IXT22_002135"
     CDS             complement(10665..11357)
                     /locus_tag="IXT22_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4863471.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11379..12353)
                     /locus_tag="IXT22_002136"
     CDS             complement(11379..12353)
                     /locus_tag="IXT22_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863472.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12653..13525
                     /locus_tag="IXT22_002137"
     CDS             12653..13525
                     /locus_tag="IXT22_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863473.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14107..16305)
                     /locus_tag="IXT22_002138"
     CDS             complement(14107..16305)
                     /locus_tag="IXT22_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4863474.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16537..17529
                     /locus_tag="IXT22_002139"
     CDS             16537..17529
                     /locus_tag="IXT22_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863475.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17589..19010
                     /locus_tag="IXT22_002140"
     CDS             17589..19010
                     /locus_tag="IXT22_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAQ4863476.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19003..20502
                     /locus_tag="IXT22_002141"
     CDS             19003..20502
                     /locus_tag="IXT22_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAQ4863477.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20541..21935
                     /gene="uxaC"
                     /locus_tag="IXT22_002142"
     CDS             20541..21935
                     /gene="uxaC"
                     /locus_tag="IXT22_002142"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4863478.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6668 a         4494 c         3823 g         7039 t
ORIGIN      
        1 cattaaaaaa aataaaggtc aagctaaaat attatttaag cttgacctta ttataatttc
       61 aacgattgtc aaaagtattg tttgcagctg tgttgccagt ttctatagat aaatcacagc
      121 ttttgaaaca taagttttgt actgcttcga ttcgcccgaa ttcttttgca gttatttggc
      181 aatgagaaaa gcagacatct tctataggct tttcaggaaa tgctactaaa tcaaaagctc
      241 gggaaggaag tgagtaacct ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt
      301 tgactttcgt catttgcttt gattcaggta tttcttcagc cactgcttgc caactttctg
      361 gcatttgagc aaggtcattg ctattttttc tattgtattc attatgccag tccattatcc
      421 aagaaaaagg aaattgtaca tcaatcatat tcagattttc taccctgata ttttcgatca
      481 ctccccctct ttcttttgaa gatttcattc gaataccaca gtctgactga aaaaaattga
      541 tatcgtgaat atatacgtca ctaactccag cactaacttc gctaccaata gttacaccgt
      601 atcctgaacg gattttacat ctagcaacct cgattcttga tgattttcga ttgactcttg
      661 caccattgcc atctctgcca gacttaatag caatacaatc atcaccacag gccaaatcac
      721 attcatagac acgcacattt gttgaagaat caatatcaat cccatctgta cttggtccat
      781 cattgttgcg gatgattact ttttctacta atacatcgtt agaataagtg atttgcaagt
      841 tccaaaaacc tgatttctga aaaatcaaat cacgaacaac aacatgttct gcatgataca
      901 gtaaacaagc gcgtggacgt ttaatagcat aatccgcaat ccaacgaagt cccttttgat
      961 cgtattcagc tcttgtcccg cttttttgat cttttcccca atacagctcc caccaatggt
     1021 ctccttgacc gtcgattatt ccttttcctt ctataagaat atctttcgcc gagagaacat
     1081 tcaaaatcgc tgctggccat ttcatttcta cgccggctac tcgtgtatcg atttctggaa
     1141 atgcttcgat atctgttctc cccttgagga ctgcaccttc ttcaaagata agatgactct
     1201 tatcttttaa aaaaagggct ccgactaaat aaatgccttt tggaataaat acaggtaagt
     1261 gttctttcgc accttgatcg attgcttttt gcagtattat tgtatcatct tgttgagtgt
     1321 cgtttgtttt aaagttcaaa gcattgataa tccctttttt tgtccgcaat acgtttctcc
     1381 ctatctttca ttgatttttt tcaattcttc accaataaat acagtttttg aacgattcag
     1441 tgggtaacct actagcaaaa tgattgcgga tacaaataag cagaatgctg gtaacaagtt
     1501 tgccatcgta taaatccttt cttgtactaa aactgattgg atggctccac ctgttgtaga
     1561 cgattggtaa ccaatgagtg ccagcataaa tccgcctacc gctcctgcac atgcttgtcc
     1621 tacttttctc gcaaaagaat ttactccata tactgttcca tcttctctta agcctgtctt
     1681 atattgatga taatcaatca cgtcagtaat gaatgcccag accatcaaat tgaataaacc
     1741 agatcctaaa gtagcgataa ataaaagaat cagatatacc catgcatttg ttatatgaag
     1801 gaaatacatc agcaagtaca tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt
     1861 tttaccaaat aattttgtca gctttgtagc aaatggtgct aaaactacta ctgttccgta
     1921 agtaaataaa agagcaacag acattgcttg tttattatgg aagtaatcat tgaataaata
     1981 agtcatattc gtcccagcta aaatctgatt gatcacaatg aaaatgtcaa caatgactaa
     2041 aataatcagt gctcgattag ctaacaaacc ttttaccaac tgagaagcag atactttttc
     2101 gtttttgaca actcttactc tttcagtagt caatttacaa gttaacatat atgcgacaaa
     2161 tgctattgca gcacatccga ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg
     2221 tccactcttg ttatgggtat acattaaaat cggaatgaag aatcctgtag ttgatccgcc
     2281 aatcgcagaa ccaatgcttc ggaacgtgga caacgaggtg cggtcattag gatttgagct
     2341 aattgctgct gccattgctc catacgggat attgattgtt gagagaaaaa tcccataaac
     2401 aatgtatgaa acaaaaatat aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg
     2461 caaaaacaaa atgacagtca ctaagcaaaa tggatacttc atttttctga tccaaggaat
     2521 aaatcggcca gtttctgtta actctgagac atcacataat cttccaacca tcacatcagc
     2581 aaacgcatcc aaaattctcg aaatcaagaa taacgtacct acgattgccc ctgaaacgcc
     2641 aagaacattc gtataataaa tcatcaagaa actattgact aaacctaaaa taaaacagtt
     2701 acctagatca ccgaacatgt agcctatctt atcggaaatc ccaaattcct ttttttcttt
     2761 ttttactgta tttgctgtaa cagcattttg tgaaagcatt tgaattcctc ctacctcttc
     2821 tagtaaacgt tttcaaaatt ataactcttt ttttcttgtt tttatattca caatgttggc
     2881 tttttattgc attatcttga cagataaaaa acaaaaaata atctaaaaac attgatgcat
     2941 aagattgata acttttttta cataacaata tatacaaaca aaaaaattca ctaactagtg
     3001 aaaataagtt agtgaacctc atttattaaa gaattaaatt acagatgatc ttttccatca
     3061 tacttgaaaa actcaaaatc agcataactt cctctttttt tatttagatc atgcactgct
     3121 atcccgataa aatttccagt aaaccctcct gagagtatac acatgttttt ttgcggacct
     3181 actttcttcc attcttcagt tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt
     3241 acagtgactt tcaaaaaagt cttcttttct gtgagtggaa tcgtccaatc ttctatttgt
     3301 gctactccgt tttctgattc tatcatacgt aggcattttc ccttgtcctc attccaagta
     3361 acataacaat aaatataatt ggattcattt aagtacagta ccagtccagc catctgatta
     3421 aaattattag gcatgtattc aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga
     3481 atagctaaca aatgatgttc gaaggtagat tgaagagatt caccggaaat cagacgtaaa
     3541 aaacctggtc tacattttgt atcacaccaa tcagcatttg gcaaaatgcg tctggcattc
     3601 cagttcttct ttagctctcc ttcaaatgta tccataaact gatgatcttt ttcttgttgt
     3661 acctcttcat ttgtctcaat cattatttct tccatcggag ttgtctggct atctttaagt
     3721 cttaaccaat cgtcggacgt ccaatacact tcttgaatag cggtttctct tcccaaaata
     3781 gccgcaccgt ttaatggtct ggtacaaaga tatgtcatgt accatcttcc tgacggggtt
     3841 tgtactaagc tcccatgtcc tgtacattgc aatgtagaag caggtttgtc actagctgtc
     3901 agcataggaa aaccaggatc aagctcgtaa ggaccagtaa tattctttgc tcggcaaact
     3961 gtaactgaat gtcctcttcc tgtaccgcct tctgccgtca tcaaataata atacccgtta
     4021 cgaaaataca aatgtggtgc ctccgttttc gctaattctg tacctgcaaa tattttatag
     4081 atgggaccat caagcttctt cttctctgca tcatattctt gtaatacgat accgctggat
     4141 ttattcggtg tgtccagacg ataatcccat agttcattga caagccattt ttttcccgtt
     4201 tcaagatcat ggaacaaaga aggatcaaag ccgttactat ttaaataaat tggttcggac
     4261 caaggacctg tgatctcaga tgcagtgatc aaataattgt ggacatcttt aaacggacgg
     4321 cctgcacttt tgacatctgt gtaaacaaga taaaacaatc catcagcata actgatctgt
     4381 ggcgcccata tacttccatt tgtaggattt ccttgcaaag atacttgagt ggtcaaaata
     4441 tccgttgtat gtgaccagtt gactaaattt ttcgactcat atactcggat tcctggaagc
     4501 cattcaaaag aggagacaat aatgtaatac cgctctttca ctcttaatat attaggatct
     4561 ggattgaatc ctcttaaaat aggatttttc actttgatag tctgcatgat tcaggctcct
     4621 tttctcattc ttactcgata taaactgaat gccccagctg ctaaaaaagc aagtgaaata
     4681 aacaacacaa cggcaaacag accagtcatg tcctgtaata atccaaatgt attttctaaa
     4741 gacaaagttg aatgatctac agcaagcgac tgataacttt ttttaaactc tgacgcagac
     4801 atattactta aagtaactgc taacccgcca aagaaaatca aagatagact gccaccgacc
     4861 attcctagca atagttccca ttttcttttc atttctgaac cccctgcttt tctaaatgta
     4921 tccattcagg tcttttgatc gatgtttcat aattgttatt acgttcagag aatttgacag
     4981 tctgttcatt tttcttgtca tcccaattat cccaaccagt tgggtgaaca tgcccaccta
     5041 tcttacacgc ttcaaataag acatttgcat acggacgcca cggtcttcct aaatagacgt
     5101 ttctagtatc aggttctgca gtcaaggtac agctttcaaa acgataccct gttttttgat
     5161 ttttcggcgt agatgctgct gtgatgtatc caggattttt actggctaag ctatggatat
     5221 gacactgatg aaaaacggca tctgccccac caaatatgaa atccaccgtt ccttcaatcc
     5281 agcaatattc ataggtctga cgacaatact caggattggc agaagccggt gtacaaaaag
     5341 gagtaccatc tttttgcaaa tcaggcaacg gacccgtgca taaggtatcc tgataaccag
     5401 atagtcgaca gttttttaaa gatacgcgat ctcctgaatt gaataaagca acagcctgtc
     5461 ctaccttttc tcctggacct gctgtatttt cgatgtgaag attttctaat acgacattcg
     5521 atccttctaa gaaaaaagta gcacttcgga aagtccctaa ctggctaccg tcaagatact
     5581 cctgttttgc aaaacgatta ccggagataa ctactgttcc tgctcccaca agtttaaaat
     5641 tggataatct gctttctata tattcatcat atcttccttc ttttactatc aagacctttg
     5701 gatggctatc cggcaggcct gccaaataat cgattccttc ttggatagtt tcaaaatccg
     5761 tcggggtatc tatagcattc tttccaatta tcagtttgtc tttcatcctc ataaatgctc
     5821 ccttatgaat tgtttccaaa tatttctcat ttcttgtgtt tccatatgac cgcctgttaa
     5881 agaaaaagaa gaaaagtttt ctggactacc cattgattga tactttttgt ccagcccttt
     5941 tctcagcttc agtacgcctt cgtccaagca catcgtatcg ttttttccaa ctaagctaag
     6001 acgagggcgc ggagcgattt tttcttggat tgctaacgtt gtataagctg tcaatagatt
     6061 tggcacatag taataaaacc catgatgatc taggcggcga tgtagcaaaa gtgtttcgat
     6121 gtccacctgt gccgctagat caatacaaac tttgacacga gaatccaatg ctgtcaccca
     6181 ccagcttaat aagcctccca tagaaagacc aatcgttgcg agccgttgag tatctgtgtc
     6241 ttcccttgtc tccaaataat cgatcaagct gatcacatca taaatacgca ttccccataa
     6301 cgtttttcct gttaataaaa attgtttgaa caactcgctt tcagaaatac ctccgcgttc
     6361 ttcaaatccc caagcatcaa tcgaccaaac agcatatccc attcctgtca gtacttctgc
     6421 aaaagatgga gaagctaagt aaggagcacc atggatcaat tcacttttcc cgactgaaaa
     6481 atctccgccg tgagaatgca ggtaaaggac cgtcggaaac ggtccttctt tttctggata
     6541 agcatagagg gctggtactg tttccaattc atttaagtac aattgatagt attcaagcat
     6601 aaaaccgttt tgtttttctc ggtataatcg ttttccacta ggggtatgtc tgctagatgg
     6661 agcacctaaa aaatcattca actgcataag caaagttttt acgaacaacc agttcatcca
     6721 tattttctga ttgatttgat tggaatttct caatactgat ttctttagta ttttctaata
     6781 gaaatgctgg tccctcgtga ttttcaatcg acatctggtt aaaggaaacc ttacccgcaa
     6841 agccaatata aaatccttgt ctgctcattt cctctattcc tgtcatcata gcaggaacac
     6901 cgggaactgc atcttgggcc atcgagacat cgatattgtc aaatgtgatt tcttgtatga
     6961 attgttccgc taatccataa ataaaacctg cagaagcatg gacattcctt gccgtgatat
     7021 tcgaaaaatg gatccttctg aatgctgatg tccgttcatc tatcggataa gccttttttt
     7081 cccatacata cggttctttc cctcgcggac cacagaaata ataaagattc agtataaatg
     7141 gacacatcac attatccatg actatattgg atactcgaat atcttcaacg atcccgcctc
     7201 gacctcgtct agatttcaat cgtattcctc gatcagtttc ttggaagata caatttgaaa
     7261 tggtaatatt acgaatacta ccactcattt cacttcctaa tacgacaccg ccatgtccat
     7321 ggaccatcgt gcaatttgtg atcgtgatat tttcgcaagc gatcctttcg tacgtatctt
     7381 cagtccctgc cttgattgca atacagtcat ctcccacgtc aatatggcaa ttactaatac
     7441 gcacattttt gcatgattct ggatcaattc cgtctgtatt tggtgaatcc gctgggttca
     7501 agatcgtcaa gttatcaaac gttgcattac tgcaaagaat cgggttgatc gtccaacttg
     7561 gtgactggat caatttaata tctttcacag taattcgatg acagttatgg aaactcatca
     7621 atttaggacg aggataagcg agattatctg gttcatttct aaaagtatgc caccattttt
     7681 ttccatttcc atctaatgta ccgaaaccag tgacagagat gttctctaca ttttgagcat
     7741 agatacagga agcataaact tttcgatgga ctccttccca acgtgaatga acaacaggat
     7801 aatcttttgg atcgtcagag aatttcagaa ccgctcctgc gcttaaatga agttcgacat
     7861 tgctttttaa aaataaagct cctgttagaa attcacctgc tggaacaact acggtcccgc
     7921 ctccgtcact tgctgcagca tcaatggctt gttgtattgc ttcagtattc aattcatcaa
     7981 ttgatgcgcc aaatgtcaaa atatcataca tatttataat gcctccactt caatcaatgc
     8041 ttgcaagaat gcaccaacgc ctttttgatc attacaaata attggttcac tgatgtagta
     8101 agcatatgaa ccatctcgct gatctgctcc gcctaaccct gctacttgac agtttttatt
     8161 caagttcagc cagccttctt ttgtttccag aacaaattca tcaagtaatc cttgatgtga
     8221 tttcttcact tgtggaagcc attcttcttt gttcagcagt cccaaacgta ttcctttagc
     8281 cattgcgtaa acaaacatac tactgccgga agcttccaga taatttcctt tccgttttgt
     8341 ttctgttgtt acttgatacc atgtcccgct gttttcttct tgatatggaa gtaatgcagc
     8401 cagtgtcttt tctagaattt ctttcagcaa agaacaatct gtttcttcat gaagtaattc
     8461 ataggtatct gctgcagcca tcaaatacca gccaatcgat cggctccaaa aatgatggga
     8521 tagacctgtt tttggatcag cccatggttg gaccttcttt tcatcccatg catgaatcag
     8581 caaatttgtt tttggatcga atagatgttt ataactgatt tcaaactgtc tcaaaacatc
     8641 ttggtaatct ttttcttcac taaaattctg gataaattca gcataaaaag gagaacccat
     8701 atataagcca tccaaccaaa tttgataagg ataaatttct ttatgccaaa aagctccttc
     8761 ggatgtgcgt ggatggtttg ccaactgctg ggaaaggagt tctgctgctt ttttatattt
     8821 ttcttcgcct gtttctttgt acaataaaaa gaaaagcttt cctgtattta catggtcgat
     8881 attgtattct tcaacgctgt agccacggat cgttccatct tcttgcacga aatagtcgat
     8941 attgtctttt atgaaatcaa aataaatttt ttcttgggtt cgttcccaaa gtaattggaa
     9001 ccctttaagt acgacgccat agtcataaga ccattttcct ttataccact tttcttcata
     9061 taagcgaggt gttctttcca tgatactttt tgctaatttc tttgaccagt tttccattat
     9121 ttgctctcct ttaaaaatta aaataggatt tgggacaaat accaagaagt atttgtccca
     9181 atcgtctata ttactgtgcc gctgctttgt atgcttcctc gtactcttgt gtgattcgat
     9241 cgcctccttg tgctttccag tcttctacag cttttttgaa tccatcttcg tcaagctgtc
     9301 ccatgatgta ttgcaccgta gcatcaatga cgattttttc aatttctgat cctacttcat
     9361 tgttcgtcgg tgaatccaat ggcacagaag gatccattac agcaaattct tcattttctt
     9421 tgatcaattg attagagaat tctttttcag ggtctgtatc tttgaaagag aacgtcactt
     9481 cactaggacg agagcttgat aacggttgca cctcttgttg ccaaagatcc atatcgataa
     9541 attcgataga accatcatca ttcaattcat aatgcgttcc ttcgataccg ccagtcatca
     9601 atttatacac atcttcttct aaaagatcat caacaaattg aagtaatttc ttcaattgtg
     9661 cttcgtcttt tacttgagat ttgggaaatg ctagcaagcc gccaatacca tttccttctg
     9721 accaaacatg ataaccgccg ccttcaccat ctgagatctt gtttacaggc actaattcca
     9781 tatcatcttg aataccttga cccatcgtct tcagattctt gatatccacc attccagtgt
     9841 agattccagt tcttccttgt gcaaattgtt cttgctgatc agtcttttgg gtaactgcaa
     9901 agtcttgtgc caaatagcca ttctcaaata gatctcttga aaaattcaaa gctttcatat
     9961 actcttctgt atcaaattct ggagtgaatt tgccattatc gtctacagcc cagccatttg
    10021 gtgctccaaa ataagaagtg aaaagtttaa agctggtata acgaatatca ctaggcgcac
    10081 gatcgccaaa accaactgtg tcgtccacac catttccatc aggatcgttt tctgtaaatt
    10141 gtttagctac ttcataaagc tcatccatgg tagttggaac atctagtcct agattatcca
    10201 accagtcttt tcgaatgact aagccagcac gagcgtagtc tttttgtatc ggtacgccgt
    10261 acaaggcacc gtcgatactc gcagcttcga ttctatcttc agaaatttga cttaaatttt
    10321 tatagtcttt taaatattct gatacatccc agaatacgcc tgattttaac gcattgcgga
    10381 cagaagagtt tttcaacatc gcaatttgaa gtgtaacgat atctcctagt tcatcagaag
    10441 ccaatgcagt tgttaatctt tcttcttttg aagcatcagg aatccagttg aatgtcagtt
    10501 ccgtatcggt tttttcttcg atcaagttca caatcgtgtc tgtaggcggt gaagcatgat
    10561 gcaaaatatt taaccaagtg attttagctt ttccatcttc tgtctctgaa gaactgttac
    10621 ttgaactgct gccgcatgcg gcaagtgcta gaattcctgc aaaactaaga cctaatttta
    10681 cgagcgttgc ttttttcata aattttctcc ttcactgttt taataatatt tttgttttct
    10741 tctgtttttt ctgtatatga gttcttccat tccaaatggc aaaatataga atttgctgtc
    10801 cacgtgactg cggaaaagaa gagactgcca ccgataaagg ttaaaacacc tggcattgtt
    10861 tggatgatca tcagataaat ccctaccata cttaatatca acactaatga gtaatgaaga
    10921 tgtgagaatc cgaataaaaa tgccattttc attttgaaaa aatatccttt ccaatcataa
    10981 tgagccatga ttgggaaaat atagagtgct gagagcacat atatgaacgc agcaatatac
    11041 aaagcgatcc taagatacca attgtgtatg aaagaaagat ccacaagtaa aacaatcccg
    11101 atggcgccat atatccagct catcagcaag gtttcacgat agttttcttt aaaatatgtg
    11161 aagtacgttt tcgtcaaagg aaacgtttct tttgagcgca gccattttct aatcactgca
    11221 accatcgcat acgatgcagg accgaaagta aaaactccca aacctgcgat gactaaaccg
    11281 ccccacagaa aattcaaata aaccaactgt aaaatacgat ttagccttcc gtttatttta
    11341 tctaatgact gcagcatatc tttccctctc tttctatctt agtaaacgcc gtcttctcct
    11401 agctttttgg caatcttatt agctaaaatt accataaaca atcctacgac ccctttaaac
    11461 aatcccattg ctgtactgaa acttaactgt ccattcttca atccagctgt ataaatatag
    11521 gtgtcgaaaa tttctgcaac gcttcgattc aatgaattca ataacaagta catatgctcg
    11581 aaccctaagt ctaatgtctg accgattttt agaatcagca aggtaatgat tactggacga
    11641 attgccggca atgtaacatg ccatgttttg cgtaagcgtc ctgctccatc catttctgca
    11701 gcttcataca actgtgtatc gactgcagtt atcgctgaaa ggtagatgat cgtagaccag
    11761 cccaactctt tccagatcac ttgtccgata tatactgtgc gtgtccattc aggggatgtt
    11821 agaaaactga ttttttcaaa tcccattgtt gcaaggaatt cattcaatac ccctccgtca
    11881 acattcaaaa atacataagt aatcgaaaca atgattaccc aagacatgaa gtgagggatg
    11941 taaatgatcg tttgaatccc gtttttcaat cgtttgttcg ttacttcatt taatagtaaa
    12001 gacaaaatga ttggcatcgg aaaaaacacg aagatattta atccgaacaa gatcaacgta
    12061 tttcttaata atgtaaagaa tgtcggttct gtaaacaaac gaatgaaatg tttgaaaccg
    12121 acccaaggac ttcccattat tcctaaaaat ggttgataat cttgaaaagc aataacgagt
    12181 ccccccatag gaagatacct aaaaatcaag aaataaagga ctcccggcag aatcatcaca
    12241 tataaaaatt tattcgtttt gattcctgca attatttttt ttcgtcttct gagcttttct
    12301 tcttttttcg atagcgtcag ttgaaatggt tcttgtttct ttacactttc cataagcccc
    12361 tccttagttt tgtgaatgtt tgctgcttat gacttcatga tagataacta tctgaattac
    12421 gtatataatc atttttatcg taagtaaaaa cgcttacata gcaatgattt ttgtgctata
    12481 caaaacgata aagtgtattt tttcacaaat aaactacgca tagcaaacct tctatttttt
    12541 tctatctgac acttagcata ggaaatgatt atatacgtaa tctttcaccg atgataaatt
    12601 gaacatatag aaacagaaac atttaattta ttttgaggag gagcctatct atatgaaaaa
    12661 gaaagtctct ataggagaaa gaagttttac acttttcaac aatacgtttc taattttgct
    12721 agctttgatc tgtatcgttc cttttttaaa tatcatcgct acatcttttg cttctacaca
    12781 agaagtcgtc gcgaaaaagt ttatcctttt tcctactacc ttttctttag acgcgtatcg
    12841 ctacattctt tctacgccga ccatttttag agcacttgct gtttcgattg gtgttacagg
    12901 tgtcggaacg atcgtcagta tgtgtgcaac ttcactgatg gcctacggtc tttccagaaa
    12961 gtatttgttt ggtcgaggtt tcgtcaactt tcttgttgta ttttctatgt tgttcagcgg
    13021 ggggatgatt ccaacgttct tagttgttcg ttctctaggg ctggtcaatt cttactgggc
    13081 catgatcctg cctgtggctg ttaatgcaat gaatatgatc attatgagaa actttttcca
    13141 agccttgccg gatagtttgg aagaatcagc aaaaatggat ggttgcacag attttggtgt
    13201 atttttcaaa attatgctgc cattagcttt accgtctatt gctactatct cgctttttta
    13261 tgctgttact tactggaaca cttatatgac tgctattttg tatatcaacg attcatctaa
    13321 atggccgata cagattcttt tacgccaaat cgtcattgta tcaagtggga tgcaagcaga
    13381 aagtagtgcc gttgatgtga ttccaccagc acaaacagtt aaaatggctg ttatcgttat
    13441 tgcaacagtg cctatgctga ttgtttatcc ttttgttcag aaatattttg tcaaaggagc
    13501 actcgtaggt tctgtcaaag ggtgattatg tactgaacgc aaaatggtag ttgtgtcaga
    13561 agtggtcagc ttcaagaaat aagaaggcat ttacgaaaat tgcttcttaa atttttgtga
    13621 aatttcggct tatttttcga agaatctact cctggaacac cgtgtatcag aggttgtgaa
    13681 agagacgttc agccttgagc gatgataaaa actctcacaa acattgcgac gagtaaccca
    13741 caggagcaat aagaagcgat tttgaaaaat agcttcccat atttcacaaa attatgcctt
    13801 attgtcgata gcctgtctct tgaacgccat ttattcgtaa aaaagaactg tgacaagact
    13861 tttgtcacag ttctttttgc gtgcttagcc ttgaaattta actatccata aatacaaata
    13921 ctagggttat tctaacttct tttattgctt gaatcagtcc acaagaaaaa cagcctcttg
    13981 attaaacggc gtttatcttg ttgattctgc ggcaataaaa tcagccagca gcaaaacatg
    14041 aagtgctgtt ttttgctgtc ctcttttatt gcttgaatca gatcacaaga aaaacagcct
    14101 cttgattcac aaatattttt ttcgatattc tcccggcgta atcgattcct tctttttaaa
    14161 gaaacgaata aaattttgcg gatttcgata ttgcaatctt tctgcaatct cttttacgga
    14221 gaggttagtc tctttcaacc atttttttgc tacctctaaa cgatgatttt gaacaaaatc
    14281 accaaatttt tctcctgttt cctttttaaa tacattactt aaatagttag ggttataatg
    14341 caacctatca gcgatcacat ctaaagacag atcacgatca tattctgtgt agacgatatg
    14401 cataatattc tccgacaaat ttttaaattc atgatcagtg attgcttgag agcattctgt
    14461 gattggcaga actaattgtt ctaaaacaag tttttctagt tctttgggat gataattgtt
    14521 cagtgctttt acataaattt gtttcatgtt atcaaagttt tttgaatcta ctcccaataa
    14581 ctgtcctaat tgaacgagtt cattgatcaa gcggaccgaa actacttccc gactcaaagg
    14641 atttttattt tgtgcaaaca atgcatcaat caattcatgt actaaattct tcacttcctg
    14701 atttccagaa cgaatggctt caaacaatcg attttgttct tctatcggat atctaataag
    14761 tgttttttca tgagcagcag gaacgatttc ctgataaaaa ataattgaac ttggaccagt
    14821 atttacacga taatacaggg cttcttttgc ccgatcaacc gattgcttgc tttcattcag
    14881 cgtttcgaac cggttactga tgcctatact gatagttaaa ttcaagtatt cttttacacg
    14941 tttttgaatg agtcggcaat actccatgac ttttttgctt gcttctgcat catctttatc
    15001 cattcgataa atagtggctt gcatttcttc attcaaaacg atcggcagca ttcgattttc
    15061 ctttggcaca atttccgtga tcatgttgtt gatcgctaaa agtagcaaat cacgctcccc
    15121 accgtgacta tcttctaaca gatcgatttg aaccaaagct gtataatagc agtcattttg
    15181 agaactataa ccaaattgct gcaaccgctg atctagttct cgcctttcta ctcgatttct
    15241 aaataaacta agtacaaata gcgtttccag ctgtggcttt tgggtaacta agtgtgcact
    15301 taacgcttct ttttctccta tgatccgact gactgattga gcgaccaaat ctagttcttt
    15361 cccactgaat ccttttgatt taagattcag acgttcctgt atttgagaaa tcggacgggc
    15421 aaatctgtcc gaaaataagt aggaaaaaag accaatgagt cctaccagtg ttaaagacac
    15481 tgcaactagc ccgattctca gattgcggat cattgcgcca attgcactag agtcaacttc
    15541 taatctgtaa atccaattat tataatctga tttcagtact atatacgttt tatctttttc
    15601 tcttatcact ttcagctgat tgtaatctag atccacgtcc gttaatacag ttggttgctc
    15661 tttatttttt actgtctgag tagtaaaaag gttgccaact tcgttttcaa tagaaagtat
    15721 gtcttctcca ctttcaccaa caacttgttc tattgtatgt ttctctatcg tagcaattcc
    15781 caatgcatat ttttcttttt caaacattgg caaagaaatc accatttcga ttcctttgtt
    15841 tttcttttgc caaaataaat tatttttgtt atttatgtac ttctgttgat acttttcaac
    15901 ttcctcttcg gtcagttgac tcaacgatcc attgattact ccccatttac cagccaaact
    15961 gactaaatca taattattat catccataac aatcgtttct ataaaattta gttctttcct
    16021 gatttcagaa taagtggagt aatctgtata tgtcagcgga tgcttgaata tgtccgagaa
    16081 atttttggtc gaaccatacg tagaaaacga atattcaatc gttctaattt tccattcaac
    16141 gttagtttta acttgcctga gcaaattctt tttgtctgtt aaataactcg attcgatcga
    16201 ttcataggta ttctggtaaa tgaataaact aaatcctatg acaagtacgg ctcctaataa
    16261 aaacatcggt aaaaatattt tataaaatac tgtacttttc ttcattttct tcctctcctc
    16321 cttttaaaat aaaaggcttt catttttctg taaaattgat actcatctaa ttaaatgagc
    16381 attccccgct ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt
    16441 gcaatctttt catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc
    16501 gttaacaaaa agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatatcgct
    16561 aaagcagctg gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata
    16621 aaaaatgaaa caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac
    16681 tatagtgcaa aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt
    16741 ttgcataaag gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta
    16801 ttagacacaa attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc
    16861 aacctgcaac gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc
    16921 atcgactatc tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat
    16981 ccagcggtta tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac
    17041 ggtattggat gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg
    17101 acaaaagaac gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat
    17161 ctagcctatt ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac
    17221 ctattatcac tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt
    17281 ggtgcattga gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc
    17341 gggttcgatg attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag
    17401 cctttgaaag aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg
    17461 acgatcgaac aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat
    17521 tacttgtaaa ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg
    17581 aagtttatat gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag
    17641 ttcttcagtt tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc
    17701 tgaataacca acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc
    17761 ttggaaatat gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca
    17821 atggcgaaat cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt
    17881 atgatgaatg ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct
    17941 ccaatacaac agaggcagga atccaattcg tggagactga taatttaaca gatactcccc
    18001 cacagagctt cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag
    18061 ctggctttac catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa
    18121 tcattttacg ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa
    18181 aagaaaatgt tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag
    18241 atgcaggtgt tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac
    18301 cattcatgct ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac
    18361 aggctggctt gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc
    18421 atttgcttaa tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa
    18481 ctgtagaaga agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc
    18541 tagaattgat tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa
    18601 tcaaagaacg tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata
    18661 gtgtttcaaa gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa
    18721 atcaggtacc accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg
    18781 atcaagtaaa gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg
    18841 ataatggaac agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt
    18901 ctcaaatacc gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag
    18961 gtgtccggtc agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa
    19021 ccaacaatga aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa
    19081 caaacacaac tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt
    19141 cataagattg cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca
    19201 atcggtcatg tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa
    19261 accaatcttt ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac
    19321 ctttttgaga accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt
    19381 aatgatttgt ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc
    19441 aaacagttca aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag
    19501 catccttatg gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg
    19561 gacgcagtaa atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac
    19621 aatacagttc ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt
    19681 ctagtggctc aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt
    19741 ttaacagcgg cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt
    19801 ttgaaatgcg gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca
    19861 ttttctgact acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg
    19921 tttggcgcag aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc
    19981 gttgacttga tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa
    20041 aacccatctc ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc
    20101 tgcacgcaaa aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc
    20161 agaaaaccag ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct
    20221 cttgcttcat ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc
    20281 tcatatgtcc caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat
    20341 tggatggatt ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg
    20401 tttgttcaaa aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac
    20461 gttcgagaaa ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata
    20521 aaaagaaaga aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg
    20581 cgaaaaagct ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact
    20641 tagatccaaa agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag
    20701 gaggcgatca ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca
    20761 caggaaatgc ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta
    20821 tcggaaatcc gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact
    20881 tgttgataaa tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag
    20941 ctcctgattt tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa
    21001 cagatgatcc cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt
    21061 tgaaggttct accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta
    21121 atgcatgggt cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac
    21181 tgatagaagt cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg
    21241 accacgcttt agacatctta cgctataaag aagcggatga aacagtatta gaagagattt
    21301 ttcaaaaagc acgagctaac aaactattat cttcagatga aatcgatgct tatcttacag
    21361 aaacactgat acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca
    21421 tccatgctta tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct
    21481 atgatggaat gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag
    21541 aagaaacgga tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg
    21601 cgattttagc tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt
    21661 ctggatggtg gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg
    21721 atggtagtgc tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct
    21781 acactagaca tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc
    21841 gaggagaagc acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata
    21901 caaatgctaa aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat
    21961 caaaaacagg atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga
    22021 ccaa
//
LOCUS       DACGLI010000051        20801 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.053, whole genome shotgun sequence.
ACCESSION   DACGLI010000051 DACGLI010000000
VERSION     DACGLI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.053"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..300
                     /locus_tag="IXT22_002143"
     CDS             <1..300
                     /locus_tag="IXT22_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4863479.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(724..894)
                     /locus_tag="IXT22_002144"
     CDS             complement(724..894)
                     /locus_tag="IXT22_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4863480.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1088..1267)
                     /locus_tag="IXT22_002145"
     CDS             complement(1088..1267)
                     /locus_tag="IXT22_002145"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863481.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1277..1501)
                     /locus_tag="IXT22_002146"
     CDS             complement(1277..1501)
                     /locus_tag="IXT22_002146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863482.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            1654..2766
                     /locus_tag="IXT22_002147"
     CDS             1654..2766
                     /locus_tag="IXT22_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4863483.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="IXT22_002148"
     CDS             complement(2844..3137)
                     /locus_tag="IXT22_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAQ4863484.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="IXT22_002149"
     CDS             3305..3619
                     /locus_tag="IXT22_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAQ4863485.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="IXT22_002150"
     CDS             3640..5619
                     /locus_tag="IXT22_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4863486.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="IXT22_002151"
     CDS             5632..5958
                     /locus_tag="IXT22_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAQ4863487.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="IXT22_002152"
     CDS             5974..6492
                     /locus_tag="IXT22_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863488.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="IXT22_002153"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="IXT22_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4863489.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="IXT22_002154"
     CDS             complement(7928..9433)
                     /locus_tag="IXT22_002154"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAQ4863490.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="IXT22_002155"
     CDS             complement(9525..10115)
                     /locus_tag="IXT22_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4863491.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="IXT22_002156"
     CDS             10294..11940
                     /locus_tag="IXT22_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4863492.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="IXT22_002157"
     CDS             11989..12708
                     /locus_tag="IXT22_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4863493.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="IXT22_002158"
     CDS             13187..14134
                     /locus_tag="IXT22_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863494.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="IXT22_002159"
     CDS             14146..15066
                     /locus_tag="IXT22_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863495.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="IXT22_002160"
     CDS             15107..16564
                     /locus_tag="IXT22_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863496.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="IXT22_002161"
     CDS             16909..17523
                     /locus_tag="IXT22_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4863497.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="IXT22_002162"
     CDS             17516..19240
                     /locus_tag="IXT22_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4863498.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19237..20688
                     /locus_tag="IXT22_002163"
     CDS             19237..20688
                     /locus_tag="IXT22_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4863499.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6708 a         3511 c         4166 g         6416 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccaggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa aaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg g
//
LOCUS       DACGLI010000052        20073 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.054, whole genome shotgun sequence.
ACCESSION   DACGLI010000052 DACGLI010000000
VERSION     DACGLI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.054"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            238..2469
                     /gene="pflB"
                     /locus_tag="IXT22_002164"
     CDS             238..2469
                     /gene="pflB"
                     /locus_tag="IXT22_002164"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAQ4863500.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            2713..3474
                     /gene="pflA"
                     /locus_tag="IXT22_002165"
     CDS             2713..3474
                     /gene="pflA"
                     /locus_tag="IXT22_002165"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAQ4863501.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            3559..4485
                     /locus_tag="IXT22_002166"
     CDS             3559..4485
                     /locus_tag="IXT22_002166"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAQ4863502.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            4667..5560
                     /locus_tag="IXT22_002167"
     CDS             4667..5560
                     /locus_tag="IXT22_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAQ4863503.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            5694..5819
                     /locus_tag="IXT22_002168"
     CDS             5694..5819
                     /locus_tag="IXT22_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863504.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5953..6585)
                     /locus_tag="IXT22_002169"
     CDS             complement(5953..6585)
                     /locus_tag="IXT22_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863505.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(6733..7275)
                     /locus_tag="IXT22_002170"
     CDS             complement(6733..7275)
                     /locus_tag="IXT22_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAQ4863506.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            7410..7799
                     /locus_tag="IXT22_002171"
     CDS             7410..7799
                     /locus_tag="IXT22_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863507.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            7803..8567
                     /locus_tag="IXT22_002172"
     CDS             7803..8567
                     /locus_tag="IXT22_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4863508.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            8696..9643
                     /locus_tag="IXT22_002173"
     CDS             8696..9643
                     /locus_tag="IXT22_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863509.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            9773..10513
                     /locus_tag="IXT22_002174"
     CDS             9773..10513
                     /locus_tag="IXT22_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863510.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10804..11472)
                     /locus_tag="IXT22_002175"
     CDS             complement(10804..11472)
                     /locus_tag="IXT22_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4863511.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            11606..11893
                     /locus_tag="IXT22_002176"
     CDS             11606..11893
                     /locus_tag="IXT22_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863512.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            12309..13847
                     /locus_tag="IXT22_002177"
     CDS             12309..13847
                     /locus_tag="IXT22_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAQ4863513.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            13844..14809
                     /locus_tag="IXT22_002178"
     CDS             13844..14809
                     /locus_tag="IXT22_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863514.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            14796..16118
                     /locus_tag="IXT22_002179"
     CDS             14796..16118
                     /locus_tag="IXT22_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863515.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      16181..16285
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            16359..17102
                     /locus_tag="IXT22_002180"
     CDS             16359..17102
                     /locus_tag="IXT22_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4863516.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            17117..18109
                     /locus_tag="IXT22_002181"
     CDS             17117..18109
                     /locus_tag="IXT22_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863517.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            18121..18858
                     /locus_tag="IXT22_002182"
     CDS             18121..18858
                     /locus_tag="IXT22_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863518.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLPGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            18848..19570
                     /locus_tag="IXT22_002183"
     CDS             18848..19570
                     /locus_tag="IXT22_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4863519.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(19654..>20073)
                     /locus_tag="IXT22_002184"
     CDS             complement(19654..>20073)
                     /locus_tag="IXT22_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4863520.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         6838 a         3401 c         4095 g         5739 t
ORIGIN      
        1 atacaggtgg cgtctctttt tcattcattt ttaataaatc cttatacgtt tgcaaaaaaa
       61 gatgaaagtg ttcacaatgc ttaaatgttg gtatgtcaac gttgatttaa atatatgtaa
      121 ataaaacata aaaattgtta aataaaaaac aagaaaaccc ttgcaaagat agggtgctgt
      181 gttatactaa tcacgtaaaa actgttacat aaaacagaaa tttaggaggt ccatacaatg
      241 gagcaatgga atggatttaa aggtaccaaa tggaaagaag gcgtagacac tagagacttt
      301 attcaaaata actacactga atatcgcggt gatgacagct ttttggaagg cccaacagaa
      361 gcaacagaaa aattatggga tgaattgcaa aagttaaatg atatccaatt cgagcgtaac
      421 ggtgtctatg atatggacac agaaatcgta tcaactatta cttcacacga tgcaggctat
      481 ttggataaag atttggaaaa aatcgtcggt ctacagacag acaaaccttt gaaacaagca
      541 ttcatgccgt tcggcggaat caatatggct aacaatgcgc taaaaagcaa tggctataca
      601 ccaaacgatg aattgacaca tattttcact gactggcgca aaacacataa tcaaggtgta
      661 tttgacgctt atactgctga aatgcgtgct gctcgtaaaa acaaaatcat tacagggctt
      721 ccagacgctt acggtcgcgg acgtatcatc ggtgactatc gtcgtgtggc attgtatgga
      781 atcgactatt tgatggaaca aaagaaaaaa gatcatgata tgactggtta tcatacaatg
      841 agtgaagaag tgattcgttt acgtgaagaa atcactgaac aatatcgtgc attagcgcaa
      901 atgaaagaaa tggctgcgaa atatggctat gatatttcta aaccagctgc aaatgcaaaa
      961 gaagctgtcc aatggctata cttcggatat ttagcagcaa tcaaatcaca aaatggtgct
     1021 gcgatgtcaa tcggacgtat ctcagcattc cttgatatct atatccaacg tgatttggat
     1081 aatggagtaa tcacagaaaa agaagcacaa gaattgatcg accacttagt aatgaaatta
     1141 cgtatggtca aattcgcgcg tacacctgaa tataaccaat tattctcagg attccctatc
     1201 tgggctactt tatccattgc aggtatggga ttagatggtc gttcattagt tacaaagaat
     1261 gatttccgtc tgcttcatac attaacaaat atgggacctt caccagaacc aaacttgact
     1321 gttttgtatt ctgaacacct tccagaagga ttcagaacat atgctagcag aatcgctatc
     1381 gaaagttctt cgattcaatt cgaaaatgat aatcagcttc gtgaacaatg gggttctgat
     1441 gattgtgcga ttgcttgctg tgtatcagga acagttgtcg gaaaagacat gcaattcttt
     1501 ggcgctcgtg ctaacttggc taaaacacta ttatatgcca tcaatggcgg agtcgatgaa
     1561 gtgactggcg cccaagttgg accagaatat cgtccaatca catcagaaat actagacttt
     1621 gaagaagtga aacataactt catgaatatg atggattggt tagcagaact atatgtcaat
     1681 acgttgaaca tcattcatta tatgcatgat aaatattctt atgaagcagc tcagctggct
     1741 ttgatggatt ctgacttgca acgcacattt gctacaggta ttgctgggat ctctcatgcg
     1801 gcagacagct tgtcagcgat caaatatgca aaagtaaaag caatccgtaa tgaaaaagga
     1861 atagcagttg attttgaagt ggatggcgac ttccctaaat acggaaatga tgatgaccgt
     1921 gcagatgaat tagtttcatg gatcttggaa tacttcatgg gacaaatcaa acgtcataaa
     1981 acttaccgca actcaaaacc aacaacttca ttattgacga ttacttcaaa tgttgtttac
     2041 ggtaaaaata caggaaatac tcctgatggc cgtgaagctg gaaaaccact tgcgccagga
     2101 gcaaatccaa gttacaatgc ggaacaaagt gggttattag ctagcctgaa ctcaacagct
     2161 aaaatgaatt acggctgtgc attggatgga atttcaaata cccaaacaat caatccttca
     2221 ggtcttggaa aagaacaaga tacaagaatc gaaaacttgc gtaatgtctt agatggatac
     2281 ttctcaaaag gagcttatca tttgaatgtc aatgtattca gtaatgattt attgcgtgat
     2341 gcaatggaaa atccaatgaa atatccgaac ttgacgatcc gggtatctgg ttatgcagtt
     2401 aaattccgtg acttgacaag agaacaacaa ttagatgtct tgatgagaac ttcacacgac
     2461 agaatgtaaa aagttcgtga aaaaagtttt tcgacttagc gtcgaaagga cgttgaatag
     2521 ccatcgcatc aaaatcgaat aatcagtatg cttatttgaa agaaacgatt tacaggggca
     2581 ggacttgtat gttccgtccc tgtaaatttt acacataacg aagcggcaat tgcgaaaaat
     2641 tttgttcaga aagcttcgct tcgacagcta acttgtactt aaaatgaaat caaagaaaag
     2701 atgtgaactt aaatggaaga aaaaacaatc ggctatgttc attctatcga aactttcggt
     2761 tcagtagacg gacctggact gcgctttgtc gtgtttatgc aaggatgccg catgcgttgc
     2821 caattttgtc acaatccaga tacttggaat attggcggag ggaaagaata cacagcagat
     2881 gaacttttag ataaagcaga acgcttcaga ccttactggg gagataaagg tggtattact
     2941 gttagtggtg gagaacctct attgcagatc gattttttga tcgaactatt taaaaaagca
     3001 aaagagcgga agatgcatac tacattggat acatgcggaa aaccttttac gtatgaagaa
     3061 cctttctttt cacgttttca agaattgatg aagtatacag atttactgtt atttgacatc
     3121 aaacacatcg ataatgaaga gcataaaaaa ctaacgcatt gggacaatga aaatatttta
     3181 gaaatggctc aatatttgtc aaaaatcaac aaaccggttt ggattcgcca tgtactagtt
     3241 cctgagcgaa gtgattatga tgaatatttg atccgactag acaactttat tcaaaccttg
     3301 tcaaatgtag acagagtaga gattcttcct tatcatacga tgggaaaata caagtgggaa
     3361 acacttggtt tgaaatatcc attagaaggg atcgaaccac ctacaaaaga acgtgtcgaa
     3421 aatgctaaac gattgcttca tacagaagag tatacaaaat atttaacgcg ataggtcgca
     3481 tcggaaagaa gataagtatt gcttctttcc gtttttttgc tattattaaa taggagaaat
     3541 cacaaaggag cgaatgacat gtcaaaaatt ttagtttttg gtcaccaaaa tccagataca
     3601 gatgcaatcg gggcagccat tgcgttttca cacttgcaaa atgaattagg taaagaaaca
     3661 gaagcagttg ctctaggtac acctaatgaa gaaacacaat acgcattaga ccactttcag
     3721 ctatctgcac cacgagtagt agagtcagct aaagcagaaa atgcagatgt catgcttgtg
     3781 gatcataatg aattccaaca aagtatttca gatatcagcg aagtaaatat tttagctgta
     3841 gtagaccacc atcgtattgc aaactttgaa acagctaatc cattgtacta tcgtgcagaa
     3901 ccagttggat gtacaagtac gattatttta aaactatata aagaaaacca agtaacaatt
     3961 cctaaagaaa tcgcaggaat catgctctca gctatcattt cagatacatt gttgttcaaa
     4021 tcaccaacat gtacgcctga agatgaagca gctgcaaaag aacttgcagc aatcgctgaa
     4081 gtcgatctaa acacttatgg acttgaaatg ttgaaagcag gaacaaatct aagtgataaa
     4141 tcagctgcgg ttcttcttga tttggatgca aaaagtttcc caatgggcag ttccaacgtt
     4201 cgtatcgctc aagtcaatac agtggacctt aatgaagtga tggatcgaca agcagagcta
     4261 gaagcagcaa tggaagatga aatgaaagca aatggctacg atctgttcgt attagttgtc
     4321 acaaacatct tagacagtga ttcagaatta cttgttgctg gtaaaggaaa agaaaaagta
     4381 gaagaagctt tccaaacaac tttgaccaac aaccgtgctt tgcttaaagg tgtcgtttca
     4441 cgtaaaaaac aagtcgtacc tcaattgacg gctgtattta gctaatcaaa tggtagtatg
     4501 aagcattcaa aatgaatgga taagcgattg atataaaaag aaacatagaa catactaaag
     4561 gccgaagaaa tggaggagaa taacagtcaa ttatgactct tgttcttcct cctttttacg
     4621 taaaagcctt ttaagtaaaa taaaacggat agaaaagaga acatatatga actattattc
     4681 aaaaaataag gaaaactttt atcaaaaact gaccgatgat ccgctttttt cttcattgac
     4741 cgattatcta tatgaacatc gagaacaaga aacgattcta agagaattga aaaaagaatt
     4801 ttcgcaaaat aaattttccc attttcttga tttattgatc gatgcaggat taatcaagag
     4861 ggaagaacga agatatcatt tgaactttcc aatatttgat cctaaagatt acttgcaaca
     4921 agccacttcg gctgctgaaa ccatagctga acaattgaag agactctctg ttgatgaaca
     4981 aaaattagcg atgggagaag ttatttgggc gtattgtttc gaagatgaac ggaaagaagc
     5041 gtatttttat ggagtaagaa acagccgaga gacagaattg ctgaggacaa ctgcaggaaa
     5101 tgagaagtac cgttttatca cactttcctc tatagaacac ttcccgctta ctttggctaa
     5161 ttactttttt gtacagaaga atcagcttcc tgtaacgaag gcattcaaag aattagccga
     5221 acttattgga gacgtaaatg aatcgtactt ttttgatcaa atagaagtta tcgttgacag
     5281 gatacgtaag aataaatata aaaatcgccg gcctagtatt ttccatcagt ctctacttgt
     5341 gacgaatact ataaaggaag aagaatcatt cacattagaa ttacctattg tcgaaaaaaa
     5401 caattttgag attgaattac caacattgga tccttcattg acaatggagg aaatggcctt
     5461 tcttaaacga caaatctttt ctgagctgag caagaaattt ataccgcatg cattttctta
     5521 tatcaaagaa tatggaacag ttttagtgag taaaacctaa gagagcagta agcaaaaatt
     5581 atactgactc ttgcaggagg agcctttctc ttcctttatg gttaaaagaa ttatttgagt
     5641 attttgccta tctaccacct attagattca ctacatggtc tggaaacaaa ggaatgcaaa
     5701 aaaatggtga gaaatgtgga atgacaaagg aagtagtgat aagaaaagtt agatttttaa
     5761 ataatcaata ttatgattca gtcaagtatg gcattttatg ggaagaacta gctgattaga
     5821 ttaggaagtc catttgataa tccagaatca ctaagaaacg aatggcgagt cattaataat
     5881 ttatccaatc ttgggttatt cttttagatt gaagtgttta aaactaaaaa agcatttatg
     5941 aagtcgtaat agtcaggctt caaaatgctt tttattttgt ttgttttttc tttgccacat
     6001 aaatacacct agactgacga tgaagagcat atccaacaga tttcctgcga cttggatcgt
     6061 cgaagggttg gtcagtggca ttaaagcaag gacaaaaaag gaaaacaagc tgtaaataaa
     6121 acaggtgaca ggaactaatc gaaagaagag cggacatttc aattggctaa aaatgagtga
     6181 aaaaataaaa taagtaaaaa tggataaaat cacgactaaa ccattcatga taaagaagaa
     6241 aagcgtattg tgattaaacg aataaaaaag aattgctaaa aaagaaaacg ttttaaatgc
     6301 aatcaatacg cttgaagctt cgtttaacgt accaggatgt cgatgaaaaa aataggcacc
     6361 gaaataaaca gaaaacagta agccgcaaag agaagacaaa atcaaaaaaa acggattttc
     6421 ttcggcttct gtgatatcag aatgatccaa aagcaaccag cctaatgcac tagaaggcgc
     6481 atgtgaggtc ttaaggtatg aataacatag aaaaaataag atcgtcaaag ttgcaaaaaa
     6541 agagcctaaa tgtaaaaaat tagtggttct acgttgaatt tccataatat ctccaaatta
     6601 aattgataag tatataaagt ataataacaa attgatgagt atatgtcgat gttttttaat
     6661 caaaataata aataaaaact gtctaacatt taaaatttaa tttagatatt agacagtttt
     6721 taagtttgtg agttattttc cttgtcgttt tctcactttt ttagtccaga aaccacctga
     6781 aatatatttt ggctcataag aaatgataaa agcacgctct tcgatttctt tgatcaggcg
     6841 atacagttca cgttcgcttt ttctaggaga aagtatttcg agaactagcc gctcaccttc
     6901 cagccccatt gcagaagtct gtgtcacacc ataaccgtgt tctctcagta tacccggcaa
     6961 acttttatct tctgcgctat ttgctggcaa aatcgttgtg accatgatgt atcctaatgc
     7021 caatttgtct tcaatcaaaa ttccgacact gatacctact gcgtaaccta acgcatagac
     7081 aaataaattc agtggattat ctaaacgatc taaaacaagg gataagccga cgatataaat
     7141 cgtgatctcg accatactga caagtggagc aatcagtcga tagcctttca ttgtcaacat
     7201 gaaacgtaac gtgttcagag tgatataagc aaaattaatg aggaagatca tccccaacat
     7261 ttttggatca atcatttgta aaactccttt catttatata acaacaatat caaaaaaaat
     7321 cgtaagtgaa gaaaaattga aactttatac atacaaaaaa atgataaaat gattataata
     7381 gaattataaa gataggttag gtgattaaaa tgaaaacggt caatcgtgtg ttttgtgcca
     7441 gccacgtgct aagtctcctt ctcagtatat acttaggtgt ctattcgatt caacagccaa
     7501 ttgaggtaga gaacattgtt tttcagatgt cgctgacaga tggtttaatt ttaagcgttt
     7561 ttttcttttt gatactgttt attggtaata ttttcggtag cgttgccagt tttttgaatt
     7621 tttctattta tccactcctt tcgctagcat taggagtggt gggactttgt tctctgtgct
     7681 tatttcccga gccattcagt cctgcattta tattatttgg tacactgaac ctgttccaga
     7741 caactgttgg agcatggttg ctatggcgat caggaaattt aatgaaaata ggtgagtaac
     7801 aattgaatcc aattatattg aaacgttctg tccatcatat tccagtgtta gaagttgttc
     7861 tgaaagaatt aagagaggaa cgtattcccg ttgtcatcta ttatcacgga tggcagacaa
     7921 gtaaggagtt agttttgacg caaggaagaa aaattgcgca gcagggcatt cgtgtgatcc
     7981 tgccagatgc gatgaatcat ggggagcgca aacagccggt ttcttctatt ccatcctata
     8041 cattttggga tagtatctac ggaaatctgt ttgaatttga cacacttatc aagcatttag
     8101 aaaaaagagg tcttctacat gatcagcttg cagttggcgg ggtttcgatg gggggaatga
     8161 caacatgcgc cttgttggct aaacatcctc atatagtagc gggcgtgtgt ttgatgggtt
     8221 cccctgcacc tttggaatat ggaaaagaaa tcgtaaggcg cgcatcggaa tataattatg
     8281 tcgtaccaaa agactatttt gatttgattt catgggttaa gagctatgat ttgtcattgc
     8341 agccggaaaa gttagctgga cgtcctctgt tcttttggca tggacaagct gacgaaaaaa
     8401 tcccttatat acaaacggaa cgatttgtag aaaaaaatcg gcataagtct tacggaaaag
     8461 aaattgtttt tcgttcctca aaaacacagc gacatatggt acaaatacca ctaatggaag
     8521 aagcttccac ttttttagca aaaaatttga taaaaaagta taaataattg aaacggaaaa
     8581 tcactcatga cgatagagga ttttccgttt tttattttgg gctataataa actctgttag
     8641 gaaaatttgg tataattgat agtaagaatg acaacatgtt agaaaggaag agagcatgcc
     8701 cactttagca gatgttgcaa aacgtgccaa tgtttcaaaa atgacggtct ctcgagtcat
     8761 caatcatccg gaacaggtga ctgacgaatt gaaagagtta gttttctcag caatggctga
     8821 actggattac cgtccaaata ttgctgcaaa agcacttgtc acgaatcggt cgcagatcat
     8881 caaattattt atactggaag aaatcgacac aactgagccc tattacatga atttgctgat
     8941 gggaatcgct aaacggatcg gtaaagcgca ttattctctc caattagtta caaatgatgc
     9001 cttcgacgtc ggttcttgtg atggatacat catcacaggt gtcagaaaaa aagacttcga
     9061 ttggatcgac cgtttggaaa aaccagttgt cttgtttggg gaaaattctg aaggatatga
     9121 ttatgtagac agcgataatg aatatggtac agcaaaagca acgcaatatg ccttagaaag
     9181 agattatcaa acgattattt atatcggtat cgaagtggac gagccttttg aaatttcaag
     9241 ggaaactggt tatttatctg tgatgaagga agttgatctt cctagtaaaa tcttgcggtt
     9301 tccaaatcat tcgacagaag tagaaagata tatgacagaa aactgggcag attttacaga
     9361 taaaacttgt tttgtatgta gttcagatcg gctagcacta ggagcagtaa gagggattat
     9421 aaatgctgga ggacacttgc ccgaagaatt tggtgtgatt ggatttgatg gggtattttt
     9481 agaccaaatc agttcaccta aattgacaac gatcaagcaa gatattatac gtatgggtga
     9541 agtatgtgga gaaatgttgt taaaaaaaat agaagaaaaa ggggcgagtc aaggttatcg
     9601 tcgttttttt cctgaactag ttatcagaga gacaacgaat taagtcttat tactatatat
     9661 atatttatga aattcatcgc tattttctta aaataatcag cgcattgcta ctgaaaacaa
     9721 tgaatctgtg ctattattga gaaaagttcc atttttgaga aggatggttt gaatgaaaga
     9781 aatcagacga aaacatttcc gttttcctgc gtacgatgat gagttaggcg taaaattaac
     9841 caacgacaag aagcgagtat tatttgacgg acaagaagat cttttgactg aacagaatca
     9901 gtccccgttt gaacagatga aagaatttca tttcacgaac acgaacaccg agaaaatccg
     9961 tcgcaagcgt cgtgcaacaa atggattgaa gtcagctccg cgtaaggaaa atttggaaaa
    10021 gcataaagga aaattaccgg attataccgg ccattaccaa tcagaaatca catcgacagg
    10081 acgaaaaaaa ctttttggtg attcctctcg ttctgtcaga caaagtgaaa caaggacaga
    10141 gtccaagcat actacacgaa acgcatctgt tgacacgaag gtgcgggagc gttcttattt
    10201 tgttcctaaa tatgtacccg catcgattat cccagaccct agagaaagca aaatttctga
    10261 ggatcattta atcgaatcga tgaaaaaaac ggatgactct tatctgttgt tcgatacaga
    10321 accgacgccg tatcaagaaa aaagaaatgg tgagccgtct gtacgaacat tcaatcgaac
    10381 aaaaacgtta gaggaaacaa agcagtcaga agaaaaaaaa tcgaaaaaaa gccatggtat
    10441 cttagaacgc tcattacaag gattgatcga tgatcaagga aactctttgg gagaaaatag
    10501 ctattttaaa taagtgatat acaaatttat attcggctac agttggaaag gaaacgctgc
    10561 ggcgtttcct tattttatac tctatccgaa agtttatatc gtatcctcaa atttttttga
    10621 gtttaagcga attttttctc ccaataagta agaaaataat ggcaaaataa aaaaacaaac
    10681 tattttcgca gatcgtttgc aaaaatagtt tattttttta taaagaagat tttactgaat
    10741 aatatcattt tagtttacat aatgatattt ctgtaaatta aataaagtag tgaaaaataa
    10801 gaatcagtgc tctaactgtt caagaggatc aagtggttca aatgtttctg tagtctgttt
    10861 tgcttccaat tggggcaaaa cagatccaat ttccagatac ttcactttat tcaatgtata
    10921 agatagaata gaacagctaa gtaatgtata cagaaaatgt gtgagatcca aataaagcaa
    10981 ggagacaact aaaataccaa aagtaatcaa gaaaagactt ttgccaatct taatatgaaa
    11041 atatttttca atggcttgat aaatgatatc tgttccgcct gtgcttccgc cgaatcgaaa
    11101 gacgagaccg caaccaatgc cagaaagaat acctgtcatc aaactattga tcagtagact
    11161 atctacagca aaatgtatat gaaggctctc ccataaatgt aaaaagaaaa ctagcgcaaa
    11221 tgttccgacg atcgtccgga gaaaagcgtg ttttccaaaa agaaacaatg agataagcaa
    11281 taaaggtaaa ttaaaaagca gtgaagtgac agaaggagcg aatccaaaaa gattatgcaa
    11341 aagcaaagca ataccagtaa ccccaccatc tgccagctta gatggaatat tgattcctgt
    11401 cacagctaat ccgtagattc ctgcgcctaa aatgattccg cacaattctg taaataaatt
    11461 taattttttc atttctagcc tcttttcttt tgaaaatttt cagcaacttc tttattatac
    11521 tgacttatac tcttacttca agaggaaaat gaaaaaaaat tatttttggc tgtttctttt
    11581 tatttatcaa ataaggagtg gaaaaatgcg agcagcagac ttattgacaa ttcttacaaa
    11641 atcacccaaa aaaacagagt atcaaggagt ttttttggct caagaacaaa aactggtgcc
    11701 tgtgacaatg gtccagataa ataaagcaaa tcaatttatc tttttatttg aacacggcaa
    11761 agcaccactt gctatgaaag acatctttct ttttttgatg aagaaccgtg agaaagctgt
    11821 ttattatcag tcaaaagaag aactcattcc tctttatgga gtgaaagaga tagaaaataa
    11881 agtggtgata taagtaaaaa taagaaaaca agacgtttat gatgtcaaaa caaccatttt
    11941 ttacattttt ggcaaaaaag tgtcatgata cagtataata ttcgttgaac aggccaataa
    12001 aggtgttctc ccccacgaga tttctacttt attggctgtt tctttttatt aaaataaaag
    12061 ttgtgtgtgt aaaaaagata tagctgattc caagtgacaa tttcgtatag atttttatgg
    12121 tattcgtagt gaaaaaacga gaaccaaaaa gttgatccga ctttgttgct tggattcttt
    12181 ttttgtcagc atatttagag gtattttttt cttttttttg ttcgtgctgt aaggttaagg
    12241 caagacaagt tagttgggaa aaaggaaaga aatgtttata cttaaagaat aacagaaagg
    12301 aaggtcgcat gaataatttt atacaaacat taagtgaaag aaaaggcgag ttgctggaag
    12361 ctgcatttca acatctgtcc atttctctca tttctttgct gattgcagca ctgattgcta
    12421 ttcctttagc gatttgggca gccaatcata aaaaaatggc agaagtctta ttgcagatca
    12481 cgggtgtgct ccaaacgatt ccttcacttg ccttattagg tttacttatc ccatttgtag
    12541 ggatcggaac tgttccagca ttgattgcac ttgttattta cgctttgctt ccgattttcc
    12601 aaaacacgta tattggtcta gctgaaattg acccgtctat tgaagaagca gcggtagcat
    12661 ttggtatgtc cagaatgaga cgcttgctga aagtagagct tcccatcgca ttacctgtca
    12721 ttatctcagg tatccgaact gccttagttt taatcatcgg tacggctact ttggcagcat
    12781 tgatcggagc aggtggatta gggacattta ttttgttagg tattgaccga aatacacctg
    12841 ttttgacatt gattggtgcg atcagttctg ccttgcttgc aattatattc agcggactga
    12901 ttcgctggtt gcagcataag aaacctcgat attccatcat tactttagca gcagtggtgt
    12961 gtttatttgg cggcgtttct ttatatcagt ctgccttgtt taaaaatgaa accatcacga
    13021 ttgctggaaa attaggagcg gaacctgaaa tcctgatcca aatgtataaa gaattgattg
    13081 aagacaacac aaaaacagaa gttgaattaa aaccgaattt tggcaagacg agttttttgt
    13141 tcaatgcact ggatcaaggt caaatcgata tctatcctga gttcacaggt actgtcctag
    13201 aaagcttggt gaaggtacct gaagcaatga aaagtgctga tttgacaaaa gaaaaaacat
    13261 atgacgaagc agaagaatta ttgaataagc aattcgatat gacattatta aaaccaatgg
    13321 cttaccaaaa tacgtatgcc ttggcagtca agagatcttt tgcgaacgaa catcaactta
    13381 aaaagatttc cgatttggca gctatctctg atcagatcaa agcgggattc acactggaat
    13441 ttattgatcg ttcagatgga tataaaggaa tccaagaagc atatggcttg aatttttcaa
    13501 gtgtacaaag catggagcca agtttgcgtt accaagcaat caataatgga gatgtcaata
    13561 ttgtggatgc ctattccaca gatagccagc tcaaggagta cgatctagtg actctagaag
    13621 atgatcgagg gttattccca gcttatcaag gcgcaccgct gatgaaaaaa gattttgcta
    13681 aagaacatcc tgaaatcgtt aaagcactga ataaattaag tggaaaaata acagaggatc
    13741 aaatgattga tatgaattac caagtcaatg tcgaaaagaa aaagccgaca gaagtagcac
    13801 gaatcttcct gaaaaatgaa ggattagtaa aggaggaaga tcagtgacta aattaatcga
    13861 gttcaaacat gtgcaaaaaa agtatgatgg aaagtatgtc atcgatgacc taaatctggc
    13921 aatcaaaaaa ggagaaatct ttgttttggt tggtccttcc ggtagtggaa aaacaactac
    13981 tttgaaaatg atcaatggat tatctaaacc atcagcagga gacatctact tcaaaggaaa
    14041 atcgttaaat gaatataatc tgcagaaaat gcggtggaat atgggatatg tgctgcagca
    14101 aatcgctttg ttcccgacca tgacagtcaa gcaaaatatt gaagtcatcc ctgaaatgtt
    14161 aggttgggaa aagcagaaaa gagcagaccg tgtagatgaa cttcttcaaa aagttggctt
    14221 atctcctgat atttatcgag atcgtatgcc tagagagttg tctggaggag aacagcaacg
    14281 gatcgggatc atccgagcta ttgctgcaag cccagatgtg attttgatgg acgagccatt
    14341 tagcgcatta gatccgattt caagaaactc attacaagaa ttggttttgt ccttacacga
    14401 agaattgggc acgaccatcg ttttcgttac gcacaatatg gaagaagcaa tcaagctagg
    14461 tgatcgtatt gcatttatga aggatggaga aattatccaa tgtgacacac cagagcagtt
    14521 attgatgaat cctaaaaacg actacgttcg gcatttcttt gatgaaccga aacagacgaa
    14581 agagtggcga gtagaagatt tagtcgtcaa tggatatttc ttaaatgaaa taccagaaaa
    14641 tgctcgtcaa caagtttgct ttgatacgcc tatgaaagaa gtatattcgc ttctttcggt
    14701 gtatccaagc attgtgatag tagaaaagca aagaagtatt gggtcgctga caagtaaaga
    14761 aatctttgct tttttaagtc gagaggagga aggaaatgaa aacatatgat gcaatcatca
    14821 tcggttcagg tgtgagcggc ttaagtgctg cttatggatt gaaagaagca ggtaaaacag
    14881 tactagtggt cgaagaagat ctatggggcg ggacttgtcc taaccgtgga tgtgatccta
    14941 aaaaagtctt gttaagtgca gtagaggcac gtaatcgggt aaaacaattg agtggaaaag
    15001 gttttaacga gatcccaact gccaactggg aagaacttca aaaattcaaa cgaacattta
    15061 cggatccagt cccagaaagc cgaaaaaaac aattagcaga agctgaaatc gatcatcttt
    15121 caggaaccgc tcgttttttg gatgattcat ctattgaagt caacgaagaa gtcttccatg
    15181 cggattactt agttttggca accgggcaaa gacctacgat cttaccagtg gagggaaagg
    15241 aatacttgaa aactagtgca gactttttat cattgcctgt actgcctaaa gaaatcattt
    15301 ttatcggtgg tggttatatt gcttttgagc tagctacgat tgccaatgct gcagggagca
    15361 aagtaaccat tgtccatcat aatcaacggc cattaaaaga atttgaggcg tctttggtag
    15421 aggaagccgt ccatcaaatg gaagcatctg gcattcagtt tgcttttggt gttgaaaccc
    15481 aaaagatcat ttcagaaggt actcgctatc gtttagtcgg aaaagagacg gaattagtag
    15541 cagatatgat tttttgtgcg actgggagac agccgaatac agaatcttta gcacttgagc
    15601 aagcgaatat cgtctttgat aaacacggaa ttgcagtcaa tgattatctg caaacgagca
    15661 atccaaaaat ttttgcgtgt ggagatattg tttcaaggaa aaccccaaaa ttgacaccag
    15721 tcgccacttt tgaaggaaat tatgtagcta agcggataac ggatgcaaca agcgaaccta
    15781 tcaaatatcc gattatacct acgatcgtct acgccagtcc taaacttgct gaagtaggag
    15841 ttacaaaaag tcacgcctct tcgtcagatc aagtggtaga gatggatctt accagttggt
    15901 tcacctatca tcgtgtcaat gaaccagttg ctaaggctga attgaccttt gaccagcaaa
    15961 attatttgat tggtgctgca gtgattagcg agcaagcaga cgaattgatc gatgatttga
    16021 cactcgtcat caatcaaaaa ttgactaaaa aagagttgga tagctatatc atggggtatc
    16081 cgacattggc aagtgatctc tcctatttat tgaaataatc agcatgataa ctaaagcgct
    16141 tgttgctttt tccttcttgt gctacacttt aaaaaatgaa tacctgtttc tggggatgtc
    16201 gtagacgaca tgagagtaag ttgtgaactt agacccattg aacctgtcag ttaatactgg
    16261 tgaagggaga aacatagcag acgcttgaag cgggttacta tgtcgtgccc atttcaagcg
    16321 ttttttgtta ttcatattag aagaaaggag gtaacaaaat gaagaaaaat ctttatccag
    16381 cagtcagtat ggcattcatt ttaattattt ggcagattgt tgtcatagtt tggaaaatac
    16441 ctgcctttat tttacccgga cctgctgctg tattttctgc attagcggca gatgcacaag
    16501 tattactttc ccattctgtc acgacattaa atgaagcagt gcttggtttg gtaatagcta
    16561 gcgttctttc ttttattact gccttggcaa tggattattg gaagttttta gaaatgtctt
    16621 tttatccgtt actagtgatt tcacaaatgt tgccaatcat ggtgttaggg ccattactta
    16681 ccctatggtt tggtttcggt atgcttccaa aagtgatcct tgttgtcttg ataagctatt
    16741 ttccgatcgt agtttctttt tcggatacat tgaggaaagt atcaaaagag caaatcatct
    16801 ttttgaaaac gatgggggca gatacaggga agatttatcg aatatataaa ataccagcgg
    16861 gtttatccgg cttcttttcc ggtttaaaag tggctgctac ttattgtgtc agcggagcag
    16921 tcgttggaga atggctaagc gctcaagcag gcttagggta ttacatgata cgcgtaaaaa
    16981 acagctacca gatcgataaa gtttttgctg cgatcatttg tgtcattcta ttgagtttat
    17041 tgctgaatgg cgcttgttca ttattgaaaa aagggtatta tcgtatgctt tatatttttt
    17101 aagagaaggg gatcaaatga aaaaattatg gcttttatta ccgctactgt tgcttttatc
    17161 cgcttgtggc actgcaaaag aaacaagtag caaacaagaa ataaaggatt tgaaaaaagt
    17221 gacacttgtt ttggattatg taccgaatac taatcatact ggcatctacc tagcaaaaga
    17281 aaaaggctat tataaagagg ctggtttaaa tgtccaaatc atcgaaccag gagataattc
    17341 gacaagtatt ggtctagtag gtgcggacaa agcacaattt ggtgtaagtt atcaagaaga
    17401 tgtcacttat gctcacgcag atggacagaa tataccagtc aaagcaattg ctacagtgat
    17461 caaacataat acttctggat tcgccaccct atcagacagt aacatccatt caccaaaaga
    17521 ttttgaagga aaaacatatg caggttggca aagtccaagt gaagaagctg tcttaaaagc
    17581 tgtgatggaa aaagacggcg gggacttttc aaaactgaca atggtaggaa gcaatggaga
    17641 agggccagaa agcttaggaa aatcctcaga tatccaatgg tactttgaag gttgggatat
    17701 gatcaaagca aaagaagcgg gtattgaact aaactatatc ccattgaaag aattagatga
    17761 acggttagat tactatactc cggtaattat tacgaatgat caactgatca aaagtgatcc
    17821 agaattggta cagtctttta tggatgccac gaaaaaaggc tatcaggaag ctattaagga
    17881 tccaaatgac agtgctaaac tgttgcaaaa atatgcaaaa gaaaatgatc ggacgttttt
    17941 agaagaatca caagcattct tgtcaaaaaa ttatacggat gatcctgaga attggggatt
    18001 gatggaagaa aaagtttggc gcaattatac agcttttatg caggaaaacg gattgatcaa
    18061 gcaagatgta ccttcgcaag aactattcac taatcagttt ataaaatagg agtgatagat
    18121 atgtcaatcc aaatcagcca cttgaatgta gtcattgaaa acctgaaaat attagaagac
    18181 atccatttca ctatccctaa agataccttt acatcgattg tcgcgccaag cggagccggt
    18241 aagtcaacat tgctgaaaac tttaacagga gtccagccta tgacttctgg aacgatcaaa
    18301 gtagacgatc aaaaagtaac tggtctccat acagcattta gttatatgcc gcaagaagat
    18361 atgttacttc cttggctgag cgtctatcaa aacgttacgt tatatcaaaa aatcaatcat
    18421 ctaacaatca atgaagaaca agtaagggat tatctggata tctttgggtt aaacggctat
    18481 gaacattttt tgccggaaca attacctggc gggatgaagc agcgaacggc cttgttacga
    18541 acaatcatga atccttcttc ttacttgctt cttgatgaac catttggagc gttagatgct
    18601 atgaccagag ggcagatgca agactggatg ttgaagctgc ctaaaaaagc aaagcggact
    18661 actttacttg tgacgcatga tatcgaagaa gcaatttatt tatcagacag gattcttgtg
    18721 ctttccgccc gtccggcaca tgtgattgct gagattcaag tgcctgaaaa acgacggtca
    18781 cgtgaatggc tactgcagca atcagagttg aagcaaacga tttatcagtt attggcaggt
    18841 gaattagatg ttaagtgatg ctcattgtca tttagatggg agtcagagtt tagcactcct
    18901 tcagcaggaa cacacgattt tgacgatcat caattgtgat tcgccagaag aatggaagga
    18961 aaacagacag cttgcagcaa gtaagactca agccttaagt tacggtatcc atccttggaa
    19021 agcagatagc tatacgtttg aacaagttga gccttttttg aaaaaagcaa ggatcatcgg
    19081 tgaaataggg ttagataata tttggacgaa tgtaccgatg actacacaaa aaaaagtatt
    19141 tgagcgacag cttgcttttg cagccataaa tgagaaacct gttgtactgc acacaaaagg
    19201 atgcgaaaaa gagatcttaa attatatcca agcttaccct aatcactatt tgatccattg
    19261 gtattcttct ttggactatc aacaagacta tattgattta ggctgttatt tcagcattgg
    19321 tcttgatttg aaaaagaatc cagcagtctg gcaactagct aaagcagtcc caatcgacca
    19381 cttacttatt gaaacggatg gactacatgc agcagagtgg gctttagggg ggattttttc
    19441 agaaaaagat tatgtctcac tgcttgaaga acagttaaag acaatcgctg agatcaaaga
    19501 gctatcagtt gaagaagtta aaaaaaatac ttatcaaaac ttggaacgtt tcattagatt
    19561 aggtaaataa aaaagagatg tgacacaact agtgtcgcac ctctttttgg ctttctttgt
    19621 ataaaagtaa actgtttgat taataaatga atcttagtac caaccgtttg cttcccagaa
    19681 tgctttcgcc gcttcccaag aaccataacg tgaagtaaca tattgttctg ctactctttc
    19741 ttggtttgca gcagagtagt caccatttaa gtaagaagaa tctaattggt aacgtccgat
    19801 gtaacgtccg ttcgttgctg tgtaagaacc gcttgattct ttttgtgcga tccattcttt
    19861 tgcagagctt gtgcttgctg gagtagcagc agtttctgtt acagcaggag caggttgtgt
    19921 ttcagcaaca ggcgctgctt gtttttccgt ttgaaccgtt tcttgtacaa caggttgttc
    19981 agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt gtgcagagcc
    20041 ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DACGLI010000053        19451 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.055, whole genome shotgun sequence.
ACCESSION   DACGLI010000053 DACGLI010000000
VERSION     DACGLI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.055"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            127..3654
                     /locus_tag="IXT22_002185"
     CDS             127..3654
                     /locus_tag="IXT22_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4863521.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="IXT22_002186"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="IXT22_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAQ4863522.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="IXT22_002187"
     CDS             7442..7783
                     /locus_tag="IXT22_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863523.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="IXT22_002188"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="IXT22_002188"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4863524.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /locus_tag="IXT22_002189"
     CDS             9140..11560
                     /locus_tag="IXT22_002189"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAQ4863525.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="IXT22_002190"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="IXT22_002190"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAQ4863526.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="IXT22_002191"
     CDS             12994..13731
                     /locus_tag="IXT22_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863527.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="IXT22_002192"
     CDS             13745..14560
                     /locus_tag="IXT22_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4863528.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="IXT22_002193"
     CDS             14573..15220
                     /locus_tag="IXT22_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4863529.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="IXT22_002194"
     CDS             15236..15892
                     /locus_tag="IXT22_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4863530.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="IXT22_002195"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="IXT22_002195"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAQ4863531.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="IXT22_002196"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="IXT22_002196"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAQ4863532.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="IXT22_002197"
     CDS             18234..18752
                     /locus_tag="IXT22_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4863533.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /locus_tag="IXT22_002198"
     CDS             18859..19359
                     /locus_tag="IXT22_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4863534.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6541 a         3341 c         4177 g         5392 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag c
//
LOCUS       DACGLI010000054        19190 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.056, whole genome shotgun sequence.
ACCESSION   DACGLI010000054 DACGLI010000000
VERSION     DACGLI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.056"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            238..1629
                     /locus_tag="IXT22_002199"
     CDS             238..1629
                     /locus_tag="IXT22_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4863535.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAEIDFSQEKIYR"
     gene            1688..2491
                     /locus_tag="IXT22_002200"
     CDS             1688..2491
                     /locus_tag="IXT22_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863536.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGKRIVPEYNNAIRVFSKRRNPFNHMTVMFD
                     KKAILEVGNYQPLSGFEDYYLWARLLKAGYKGYNIQETLVYARTGKDMYARRGGMKYL
                     GSGLMGRYRIWKDGLGSVKDFIIVSCGHIFISLLPNQLRGKFYQTQLRK"
     gene            2524..3378
                     /locus_tag="IXT22_002201"
     CDS             2524..3378
                     /locus_tag="IXT22_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HAQ4863537.1"
                     /translation="MKKIQQITLKMSQEIVDFCLKNQLLCYFCGGGAIGTVREQGFIP
                     WDDDLDFFMPREDYEKFYQLWVNSEKSKKYPIQKASKNYNDHNSFTTIRDADTTFIKT
                     YQRDLDIVHGITIDIFPLDVAPVSKFSRKIQKLWALVYALFCSQVVPEKHGGIMATGS
                     KILLSIFRSPRTRYKIWSFAEKQMTKYNNEPTGYVTELCVGPKYMGNVYPAKDFESAV
                     WVPFEDTEMPVPVGYDNYLSQVFGDYMQLPPEKDQVSHHEAVYIDPEHPYTMYKGKYY
                     LTKGAEKK"
     gene            3375..4076
                     /locus_tag="IXT22_002202"
     CDS             3375..4076
                     /locus_tag="IXT22_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAQ4863538.1"
                     /translation="MITAIIIAGGVGKRMGQDIPKQFITIEGKPIIIYTLESFQHHPQ
                     VDRILVVCKSGWEETMWAYIKEFNISKVKWVITGGSKGQESINNGVQFLKDYSEDDDT
                     IIIHDGIRPLVDELVLSDVIVKCKEFGNGVTSLPYNEQIFIKKTEETTEQYVDRNTLR
                     RVSTPQAYQYGKLRAAYDRAVKEDIGMTDSSYTNTMMVDLGETLYFAAGSDKNIKLTT
                     TDDLELFKAYLKMKD"
     gene            4084..5151
                     /locus_tag="IXT22_002203"
     CDS             4084..5151
                     /locus_tag="IXT22_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4863539.1"
                     /translation="MMTLIKQPMYQEDLAKVINHTPKIKQLHGKSVLMIGASGMIGSF
                     LIDTLMAANEQLGIKIKVYAMGRNRQKLEKRFASYLELDTFEIVEGDVTEPLPKEIQA
                     DYLIHGASNTHPKAYATDPIGTIMTNLAGTEQVLKHAVATQPVRVLFLSTVEIYGENR
                     GDIEKFTEDYCGYIDCNTLRAGYPEGKRVSESLCQAYIAKHDLDIVIPRLCRTFGPTM
                     LLSDTKASSQFILNAVEQKDIVLKSEGNQYFSYVYVGDAVSAILHLLLEGEKGEAYNV
                     SSENFDLRLKELAQQLADISGKQVIFELPDEIEQKGFSKASTAVLENKKIKETGWKPI
                     FPLNESLVHTVELVKGEKYNV"
     gene            5144..6109
                     /locus_tag="IXT22_002204"
     CDS             5144..6109
                     /locus_tag="IXT22_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863540.1"
                     /translation="MCEISIIVPVYKVEKYLRKCVDSILAQTFTDFEVILVDDGSPDN
                     SGKICDEYAEKDNRVRVIHKENGGLSSARNAGIDVARGKYLGFVDSDDYIDEDMYEIL
                     YENLKIHDADISSVELIPFYGDRYKKANKEKKVIILNKKEAIKSVLEGTQFYAYAWNK
                     LYRKELFKDNRYLDGKTFEDAYIIIDLLFQTEKIVVSNEEKYFYLQRNDSIMGKSFSM
                     NNFDVIEAWQYNKEKILDAFPDLHDSYYRRLCWAYFYVLDKMVLSSSYQQIPRKKTVI
                     EFLKKNRNFILTYKGFTKSRKIAIIALSFRVDWYRKLVEQKNKKN"
     gene            6154..7128
                     /locus_tag="IXT22_002205"
     CDS             6154..7128
                     /locus_tag="IXT22_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4863541.1"
                     /translation="MCRISIIVPVYNVEKYLKKCVDSILGQTFTDFELLLIDDGSTDN
                     SGSICDELAKTDNRIKVIHKENGGLSDARNIGIEVAKGDFIGFIDSDDYIDEDMYAFL
                     YNNILKYDAELSMCGIYDVHKNKEIKKLTPFSQLVTKSEAIELVLDGKLVVANAVSKL
                     YKKELFENVRYPKGKIAEDAAVILKIINQCNKIHVDTSQKYYYYHRGDSITSKKFTKK
                     DFDIIDVWNENEKWIIKNYPQMYDKVHTRVCWAYFVVLDKLVLTEEKGLYQEKKQVRE
                     YLIDNFFFIIKNKRLTFQRKISMLLLTFGIAAYKIPVKYQYKKVKAVN"
     gene            7199..8686
                     /locus_tag="IXT22_002206"
     CDS             7199..8686
                     /locus_tag="IXT22_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAQ4863542.1"
                     /translation="MFIYILRIVIQFVGRSFFIYFLGAKYLGLNGLFTNILSFLSLAE
                     LGIGSSIIYSLYKPLAQKDESKVKALMNLYKKTYEFIGIFIGIVGVLIIPLLPLFIKN
                     STDIPHMYRYYVLFLLNSVLSYFFTYKRSLAIADQKNYLVAINDFAFLFFMNIVQVIA
                     LYFYSNFTLFLIVQILFTLFSNINISRTVDKRYSYLKEKDVVSLDKQTKDEVKKNVIG
                     NMSSKIGGVIVMGTDNILISTFVNLTAVGIYSNYSLIVTSVQNLCKQITNSITASVGN
                     FAVSNKKKDSFELFKKHFFINHSLIFFSSILLLTLMNPFISLWVGAKYMLPMSTTILI
                     VLNYSVQVYRNTSFVFIESFGLYWSQRKKPIIEAGVNLLLSLLLLIVFDMGINGVLIG
                     TIGSSLGFVIWYEAFIIYKTVFEKRFIHFFLTFWRSFIELIISAIVVFLLNEYLANGG
                     STFLQFITKTLITIVTTSILYLLLYFRREEFTFIKKILFRYILKK"
     gene            8743..9858
                     /locus_tag="IXT22_002207"
     CDS             8743..9858
                     /locus_tag="IXT22_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4863543.1"
                     /translation="MGGASIVASKIAKGLIDSGHEVFFVSYLESEKPQVESKYYDLYE
                     KKIFLFKNFSRFHKILEYRLFGGFVPSRYIKKEKEQLKKVLKKEKPDVIIFNTFIPSV
                     LFSEFLKYEFPTVKLITWMHSDPDYSLNHIAKFYKKEYRKSFERVDSIVCLSQDTKEK
                     LSLYNNHIKVIYNPLTLSGSSLISNLDKKIISFTARYDINIKGFDYLCEVAKNLPVGW
                     AIRIAGDGTEEERKELKRLIEKNGVLDKIICAGALFGDELINHYIESSIFISTSRSEG
                     LPLVLIEAMTYGLPVISFDHGGAKEILQDGNYGILIKNFDVQDMNNEIEKLSNNRLLM
                     EKYQKFSLERAKDFNEKKIIGEWQTLLNELGNEDVRN"
     gene            9855..11270
                     /locus_tag="IXT22_002208"
     CDS             9855..11270
                     /locus_tag="IXT22_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAQ4863544.1"
                     /translation="MRTSIKNFNLWKEWYLYIFFIGMIIRAINFYSLLPSTFDSIFFK
                     LIGISGVLLLGIDFIIKFNKRKVTYNILLIAYMVILVITSFVHKEYGLGENLKTIMWA
                     ILQYFLIYQFAFENSDNKRFFKRISWGFIYSWFVLVSMSMVLFFGKFGYEKYYNARHR
                     IRIGFLESRLFGTFSDINNAAIASLVVIVLILFYLYNKKVTGLNKIIFLINLPLQFIY
                     IVLSGSRSTYVVSIIIVAISSFIVVLKRNGTKKDLKNYILAIVSSIGSVLILFALFNA
                     TKILFQELLPHLKEINFFNFTERHKELMNNSQHINNTQTPDNTLVRKDVAENTDISNA
                     RITIWKSAWEIFKTSWLIGVSPKNVVSYAQSIIPDGYIAKVGIAIHNAYLNVLTSTGI
                     LGIIPFMAFLIKSFVLNVYRIIYNKCIGKDYHFVYCLVILSYALYAALNNELVYENTV
                     GTFVFWLFLGRVNSKNNSSYF"
     gene            11303..12250
                     /locus_tag="IXT22_002209"
     CDS             11303..12250
                     /locus_tag="IXT22_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4863545.1"
                     /translation="MLNYLITGGAGFIGSTLANYLGKENNVVVIDDLSMGKKENLDES
                     KHITFIEGDVADKNLMEKVMKEYHFDYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(12290..13450)
                     /locus_tag="IXT22_002210"
     CDS             complement(12290..13450)
                     /locus_tag="IXT22_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4863546.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            13615..14790
                     /gene="mltG"
                     /locus_tag="IXT22_002211"
     CDS             13615..14790
                     /gene="mltG"
                     /locus_tag="IXT22_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAQ4863547.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            14926..15405
                     /gene="greA"
                     /locus_tag="IXT22_002212"
     CDS             14926..15405
                     /gene="greA"
                     /locus_tag="IXT22_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAQ4863548.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            15573..16304
                     /locus_tag="IXT22_002213"
     CDS             15573..16304
                     /locus_tag="IXT22_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAQ4863549.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            16301..17368
                     /locus_tag="IXT22_002214"
     CDS             16301..17368
                     /locus_tag="IXT22_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4863550.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            17375..18007
                     /locus_tag="IXT22_002215"
     CDS             17375..18007
                     /locus_tag="IXT22_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4863551.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            18147..18812
                     /locus_tag="IXT22_002216"
     CDS             18147..18812
                     /locus_tag="IXT22_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAQ4863552.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            18840..19133
                     /locus_tag="IXT22_002217"
     CDS             18840..19133
                     /locus_tag="IXT22_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAQ4863553.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
BASE COUNT         6704 a         2688 c         3694 g         6104 t
ORIGIN      
        1 tatatgaata ttgtaacttg tgaataagga attagcagga gaatactagt tcagcataaa
       61 ggaagtgatg ggacttctga gacaactttc tgttatgcag aaatacacat ataaacagac
      121 aataaacgct tttccccgtt tcttttaatt tcctttacaa tttggttatt cactaggttt
      181 ttaaactttg ctatggtaag atgatagagg cattatttta tggttaggag tgtatatatg
      241 aataaaaatg gggagtggaa tgcggcacgc agaatattca ttattcttat ggatgtactt
      301 gtattaaatg tatcgatcta tcttagtttt ttgctgaaat tccagggaga agtaccagtg
      361 agaaacttag aaacctttca gcattcagca atttttattt ccatcatctt tattgcgttg
      421 aatattttgt taggagctta tgtattctat aaccgaatga tcagtgatat tgtcttcatt
      481 actgttattg gacaagtact aatagcattg gggatcatgg tagttacttt tgctggccga
      541 tggtttgcat ttccgcgtgg cgtcattttg atctcgttta tcctaggtac gatattactt
      601 agtgtttacc ggatagtcgt ttacaaactg tacttaagag tcagtcgtga taagaaagtc
      661 cttatcgtgg gtttggagaa agatgtcgca ccagctatcc aaaattttca atctaagaaa
      721 aacaataaac ataaggttga agcagtggca atcgataatt attacgaaaa tacaaaaaaa
      781 ttgatcgatg atatggatat cgtctatttg gcttctaaaa tcccagaaga tgaaaaaatc
      841 aacatttatc aattagtgac taaaaaagag aagaaattat ttttaaatac gacttttgag
      901 aatctgacaa tgataaatcc gaatattatg aattttgaag atgaaagcat cattgaagct
      961 tctgggttca gaatccaacc agaatacgaa ctattcaagc gtctctttga tatcatcgtt
     1021 tcgcttattt tactgatcct cgcctcacct tttatgctaa tcacagcgat tttggtaaaa
     1081 acaacttcac ctggaccaat catctataaa caagtacgta ttacgaaaaa tcaaaaggaa
     1141 ttttcaatct ataaattccg ttccatgagt gcgacagctg aagcaaaatc aggaccagtc
     1201 ttggctaaaa gtaacgatgc acgtgtgaca ccagtaggta aatttatccg tgctgtacgt
     1261 tttgacgaat tacctcaaat ctttaatgta ttgaaaggcg atatgtcgat tgtcggtcca
     1321 aggccagaaa gaccattttt cgttgatcag ttcaatgaag aaaatcctta ttattactta
     1381 agacacaatg tacgtgcggg aattaccgga tatgcacaag tatacggaaa atatgtatca
     1441 gattataaca gtaaactacg ttttgatttg ttgtatatca aaaaatattc attactatta
     1501 gatttgaaga ttttacttca aacaatcaaa atcttatttg ataagatgtc atctcaagga
     1561 ctagatgaag atgaaaatat tagttcatta gcagaaatcg acttttcaca agagaaaatt
     1621 tatcgctaga ttggaaaaat tttgagcaaa gaggtaggag agaacattgg aaaataaaaa
     1681 tgtaagtatg ctgctttctt tatatgataa agaaaagcca gagtatttaa aggaagcatt
     1741 aactagtatt tttgagcaaa cagtaatgcc aaaagaaatt gtattagttt atgacggccc
     1801 tataaatgaa aaacttcaag tagttgtcac ttatttccaa caaaaagatc ctcacttgtt
     1861 tacagttgta aaattagaaa aaaatcaagg attggggatt gctttagcaa ttggattaga
     1921 acatacgaaa aatcgcttag tagccagaat ggatacagat gatataatgg aaccccaacg
     1981 attagaaaaa caattagaga tcttccaaaa agatccagaa atagcgattg ttgggagtaa
     2041 tattgaggaa tttactggca cgcttagcaa tgttatcgga aaaagaattg tacctgaata
     2101 taacaatgca attcgtgtat tttctaaaag aagaaatccc tttaatcata tgaccgttat
     2161 gtttgataaa aaagctattt tggaagtggg aaattaccaa ccattaagtg ggtttgaaga
     2221 ttattatctt tgggcaagat tattaaaggc aggttataaa ggatataata ttcaagaaac
     2281 attagtctat gcgcgaactg gcaaagatat gtatgcaaga agaggcggaa tgaaatatct
     2341 tggttctggt cttatgggtc gttatcgtat ctggaaagac ggtttagggt cagtaaaaga
     2401 ttttataatt gtttcttgcg gacatatttt tattagctta ctaccaaatc aattaagagg
     2461 aaaattttat caaacgcaat taagaaaata ggaggttttt ctttgtatag cactgatcca
     2521 aaaatgaaaa aaatacaaca gattacgttg aaaatgtctc aagagattgt tgatttttgt
     2581 ctaaaaaatc aacttctttg ttatttctgc ggtggtggtg ccatcggtac tgtgagagaa
     2641 caagggttta ttccatggga tgatgattta gatttcttta tgcctagaga ggattatgaa
     2701 aaattttatc aactatgggt taattcagaa aaaagtaaaa aatatcccat acagaaggct
     2761 tctaaaaatt ataatgatca taattctttt acaactatcc gcgatgcaga tactacattt
     2821 attaaaactt atcaaagaga tttagatata gtccatggaa ttactattga tattttcccg
     2881 ttagatgttg cccctgtttc gaaatttagc cgtaaaattc aaaaactatg ggctttagta
     2941 tatgctttat tttgttctca agtcgtccct gaaaaacatg gtggaataat ggctacaggt
     3001 agtaagatac tcttatctat tttccgctca cctcgtacga gatataagat atggtctttt
     3061 gctgaaaaac aaatgacaaa atataataat gaaccaacgg gctatgtgac tgaactttgt
     3121 gtcggaccta aatacatggg aaatgtttat cctgcaaaag actttgaatc tgctgtgtgg
     3181 gtgccattcg aagatacaga gatgccagta ccagttggtt atgataatta tttaagtcaa
     3241 gtttttggtg actatatgca gcttccgcct gaaaaagatc aggtttctca tcatgaagca
     3301 gtttatattg atccagaaca tccatacaca atgtacaaag gaaaatatta tttaactaaa
     3361 ggagcagaaa aaaaatgatt acagctatta ttattgctgg tggtgtgggt aaacgaatgg
     3421 gacaagatat cccaaaacag ttcattacaa ttgaaggaaa acctattatt atctatactt
     3481 tagaatcatt tcaacaccat cctcaagttg accggatttt agtcgtttgc aaatctggtt
     3541 gggaagaaac gatgtgggcg tatatcaaag aattcaatat tagcaaagtc aaatgggtca
     3601 ttacaggtgg atcaaaggga caagagtcga tcaataatgg tgttcagttt ttgaaagact
     3661 attctgaaga tgatgatacg atcatcatcc atgatggaat ccgtccacta gtagacgaac
     3721 tggtattgtc agatgtaatc gttaaatgta aagaatttgg taacggtgta acctctctac
     3781 cttacaacga acaaattttt atcaagaaaa cagaagaaac gacggaacag tatgtcgatc
     3841 gtaacacatt gaggcgtgtc tcaactccac aagcttatca atacggaaaa ctacgggcag
     3901 catatgaccg ggcagtgaaa gaagacatcg gtatgactga ttcttcttat acgaatacca
     3961 tgatggtaga tttgggagaa actttatatt ttgctgctgg ttctgataaa aatatcaaat
     4021 tgacaacaac agatgatcta gaattgttca aagcatattt aaaaatgaaa gactaggtga
     4081 aagatgatga cgttgattaa acaaccaatg taccaagaag atttggcaaa agtaatcaat
     4141 catacaccaa aaataaaaca gctacatgga aaatccgttc tgatgattgg tgcttctgga
     4201 atgatcggct cttttttgat tgatacgttg atggctgcta atgaacaact aggcatcaaa
     4261 atcaaagttt atgcaatggg cagaaaccgt cagaagcttg aaaaaaggtt tgccagttat
     4321 cttgaattag atactttcga aattgttgaa ggtgacgtca cagaaccctt accaaaagaa
     4381 attcaagctg actatttgat acacggtgca agtaacacac atcctaaggc ttacgcaact
     4441 gatccaatcg gtacgatcat gactaatctt gcaggtacag agcaagtatt gaaacatgca
     4501 gtagcaaccc aaccggttag agtattattt ttatcaacag tagaaatcta tggcgaaaat
     4561 cgaggcgata tagaaaaatt cacagaagat tactgtggat acatcgattg taatacactg
     4621 agagcaggct accctgaagg aaaaagagtc agtgaatcat tatgccaagc ctacatcgca
     4681 aaacacgacc tcgacatcgt gattccaagg ctttgccgta cgtttggtcc gacgatgctt
     4741 ttatctgata cgaaagcatc ctcacaattt attttaaatg cagtcgaaca aaaagatatt
     4801 gttttaaaaa gtgaaggaaa ccaatatttt tcgtatgtat atgttggaga tgctgtttct
     4861 gctattcttc atttactgct tgaaggagaa aaaggagagg cgtacaacgt ttcttcagaa
     4921 aactttgatt tacgactaaa agaattagcc caacagctag ctgatatcag cggcaaacaa
     4981 gtaatttttg aattgccgga tgagattgaa caaaaaggtt tctcaaaagc tagcacagca
     5041 gtacttgaaa ataaaaaaat taaagagaca ggttggaaac caatttttcc tttgaacgaa
     5101 tcattggttc atacagtaga attagttaaa ggtgagaaat ataatgtgtg agattagtat
     5161 tattgttcct gtgtataaag ttgaaaaata tttaagaaaa tgtgtagatt cgattttagc
     5221 ccaaacattt actgattttg aagttatatt agtagatgat ggatctcctg acaatagcgg
     5281 gaaaatctgt gatgagtatg ctgaaaaaga taatcgagta cgtgtgatcc ataaagaaaa
     5341 cggcggatta agcagtgcta gaaatgcggg gattgatgtt gcgagaggca aatacttagg
     5401 ctttgttgac agtgatgatt atattgatga agatatgtat gaaattttgt atgagaattt
     5461 gaaaattcat gatgccgaca ttagctctgt tgaattgatt cctttttatg gtgatagata
     5521 taagaaagct aataaagaaa agaaagtaat tatattaaat aaaaaggaag caataaaatc
     5581 tgttttagaa ggaacgcaat tttatgcata cgcatggaat aaactttatc gtaaggaact
     5641 ttttaaagat aatcgttact tggatggaaa aacatttgag gatgcatata taataataga
     5701 tctattattt caaacagaaa aaattgttgt ttccaatgaa gagaaatatt tctatcttca
     5761 aagaaatgat agtattatgg gaaaaagttt ttctatgaat aatttcgatg ttatagaagc
     5821 atggcaatat aacaaagaga agattttaga tgcttttcca gatttgcatg attcctatta
     5881 tcgccgacta tgttgggcat atttttacgt gttggataaa atggttttat caagtagtta
     5941 tcaacaaatt ccacgtaaaa aaacagtaat tgaattttta aagaagaaca gaaattttat
     6001 attaacttat aagggattca ctaaatcgcg caaaatagct attattgctc tgagctttag
     6061 agtagattgg tataggaaat tggttgaaca aaaaaataaa aaaaattaga atgtttaaat
     6121 tagtaaataa aagaaaagga attgaaaact aaaatgtgca gaataagtat aatagttcca
     6181 gtttataatg ttgaaaaata tttaaaaaag tgtgtcgatt caattctagg ccaaacattt
     6241 accgattttg aattattatt aattgatgat ggttctacag ataattcagg aagtatatgc
     6301 gatgaacttg cgaaaacaga caaccgaata aaagtgatac ataaggaaaa tgggggtcta
     6361 agtgatgcca gaaatattgg tattgaggta gcaaagggag attttattgg gtttatagat
     6421 agtgatgatt acattgatga agatatgtat gcatttttat ataacaatat attgaaatat
     6481 gatgcagagt tatcaatgtg tggtatttat gacgtccata agaataaaga aattaaaaag
     6541 ttaactcctt tttctcaatt ggttactaaa tctgaagcaa ttgaattagt attagatggt
     6601 aagctagttg ttgctaatgc agtaagcaag ctatataaaa aagaattatt tgagaatgtg
     6661 agatatccaa aaggaaaaat tgctgaagac gcagcagtaa tactgaaaat tatcaatcag
     6721 tgtaataaaa tccatgttga tacttctcaa aaatattatt attatcatcg tggagatagt
     6781 attactagta aaaaatttac aaaaaaagat tttgatataa ttgatgtatg gaatgagaat
     6841 gaaaaatgga ttattaaaaa ttatcctcaa atgtacgata aagtacatac tagagtttgt
     6901 tgggcttact ttgttgtgtt agataaatta gttttaactg aagaaaaagg actgtatcaa
     6961 gaaaaaaaac aagtaagaga gtatttaatt gataatttct tttttattat aaaaaataaa
     7021 cgattaactt ttcaaagaaa aatatctatg ttattgctta cttttggaat tgctgcgtat
     7081 aaaataccgg ttaaatatca gtataagaaa gtaaaggctg ttaattaatg ctttagttag
     7141 gatgaattag atgaaaaaaa gcaggttaga gtattcttta ataaattctt ctatatcaat
     7201 gtttatatat attttaagga tagtaataca atttgtaggt agaagttttt ttatttattt
     7261 cttaggagcg aaatatttag gattaaatgg tttatttaca aatatactta gtttcttgtc
     7321 gttggctgaa ctaggcatag gctcttctat tatttattcc ctatacaaac cattagccca
     7381 aaaggatgaa agtaaagtaa aggctttaat gaatttgtat aagaagacat atgaatttat
     7441 tggtattttt atcggcatag taggagtatt gattattccg ctgttacctc tatttattaa
     7501 aaatagcaca gacataccac atatgtatcg atattatgta ttatttttat taaattcagt
     7561 tcttagttat tttttcacgt ataaaagatc acttgcaata gcagatcaaa aaaattatct
     7621 ggttgcgatt aatgattttg cctttttatt ctttatgaac attgtacaag taattgcttt
     7681 gtacttttat tctaatttta ctctatttct aatagtgcag attttgttta ctctattttc
     7741 taatataaat atttccagaa cagttgacaa gagatattca tatttaaaag agaaagatgt
     7801 agtttctcta gataagcaaa caaaagatga agtaaagaaa aatgtcatag gtaatatgtc
     7861 ctcaaaaata ggcggggtta ttgtaatggg gacagataat atattaattt ctacatttgt
     7921 taatttaaca gctgtaggaa tttattctaa ctattcattg attgtcacaa gtgtgcaaaa
     7981 tttatgtaag caaattacta attctatcac ggcaagtgta ggaaattttg ctgtatcaaa
     8041 taaaaaaaag gattcatttg agctatttaa aaaacatttt tttatcaacc actcactaat
     8101 ctttttttct tctatattgt tattgacttt aatgaatccc ttcattagct tgtgggtagg
     8161 agccaaatac atgctaccta tgtcaacgac tattttaatt gttttaaatt atagtgtaca
     8221 ggtttataga aatacatcct tcgtttttat agagtcattt ggtttatatt ggtctcaacg
     8281 gaaaaagcct ataattgaag caggtgtaaa cttgttatta tctttgcttt tgttaatagt
     8341 ttttgatatg ggaatcaatg gagtacttat agggactatc ggatcgtctc taggatttgt
     8401 gatttggtat gaagcattta tcatatataa aacggtattt gagaaacgtt ttattcattt
     8461 ctttttaact ttctggcgaa gttttataga attaataatt tcggcaatag tcgtttttct
     8521 attaaatgaa tatttagcaa atggaggcag tacgttcctt caatttataa ctaaaacctt
     8581 aataactata gtaacaacat cgatattata tttgttatta tattttagaa gagaagaatt
     8641 tacatttatc aaaaaaattc tttttaggta tattttaaaa aaatagcttt ctataaagga
     8701 gtgttttatt tgaaaatagc tatactatct ccagctttct caatgggagg agctagtatc
     8761 gtggcctcaa aaattgcaaa aggattaata gatagtggcc atgaagtttt ttttgtttct
     8821 tacttagaaa gtgaaaaacc acaagtagaa tctaagtatt atgatttata cgaaaaaaaa
     8881 atttttttat ttaaaaattt ttctcgattt cataagatat tagagtatag attgtttgga
     8941 ggctttgttc ctagtagata tataaaaaaa gaaaaagaac aactaaaaaa agttctaaag
     9001 aaagaaaaac ctgatgtcat catattcaat acttttatac ctagtgtact attctccgaa
     9061 ttcctaaagt atgaatttcc aacagtgaaa ttaattactt ggatgcactc tgatcctgat
     9121 tacagcttaa atcatattgc taaattttat aaaaaagaat atagaaaaag ttttgaacgc
     9181 gtggattcca ttgtttgtct ttcgcaagat acaaaagaaa aactttcatt atacaataac
     9241 catattaaag ttatttataa cccattgaca ttaagcggct ctagtttaat aagtaacctt
     9301 gataaaaaaa ttatttcatt tactgccaga tacgatataa atattaaagg gtttgattat
     9361 ttatgtgaag tagctaaaaa cttacctgtt ggatgggcta taaggattgc tggagatggt
     9421 acagaagaag aacgtaaaga gctgaaaaga ttaattgaga aaaatggtgt gttagataaa
     9481 attatttgcg caggtgcatt atttggagat gaattaatca atcattatat agaaagttct
     9541 attttcatat ctacttctag aagtgaggga ctaccattag tgttgataga agcaatgact
     9601 tatggattac ctgtaataag ttttgatcat ggtggtgcta aggaaatatt acaagatgga
     9661 aattatggaa ttttaattaa gaattttgac gtacaagata tgaataatga gatagaaaaa
     9721 ttgtctaata atcgtttact tatggaaaaa tatcaaaaat tctctttaga aagagctaag
     9781 gattttaatg aaaaaaaaat aattggtgaa tggcaaacat tgttaaatga attaggaaat
     9841 gaggatgtta gaaattgagg acttcgatta aaaattttaa tttatggaaa gaatggtatc
     9901 tatatatatt ttttataggg atgattattc gtgcaataaa tttttatagt ttattaccgt
     9961 ccacttttga tagtattttt tttaaactta taggaatttc aggagttttg ctattaggga
    10021 tagatttcat aattaaattt aataaaagaa aagtaactta taacatttta ttgatagcat
    10081 atatggtgat tttagtaata acgagttttg ttcataaaga atatggtcta ggagaaaact
    10141 taaagactat aatgtgggca atcttacagt attttttgat ttatcagttt gcttttgaga
    10201 atagcgataa taaacgattt tttaaaagga taagttgggg atttatttat agttggtttg
    10261 ttttagtatc aatgtcaatg gttcttttct ttggtaaatt cggctatgag aaatattata
    10321 atgctagaca taggatcaga attggttttt tagaatcaag actgtttggg acgttttctg
    10381 atattaacaa tgctgctata gcatctttag ttgttattgt cctaatctta ttttatcttt
    10441 ataataaaaa agtgacagga ttaaataaaa tcattttttt aattaatctt ccattacaat
    10501 ttatttatat agtattaagt gggtcacgat ctacctatgt ggtaagtata ataatagttg
    10561 ccatatcatc ttttattgtt gtgttaaaac gaaatggaac aaaaaaagat ttaaaaaact
    10621 atatccttgc tatagtatct tctattggtt ctgttctgat tttattcgct ttgtttaatg
    10681 caactaagat actttttcaa gaattattac ctcatttaaa agaaataaat ttttttaatt
    10741 ttacagagcg tcataaagaa ttaatgaata atagtcaaca tattaataat actcaaacac
    10801 ctgataatac tcttgttagg aaagacgtag ctgaaaatac agatatttct aatgctagaa
    10861 ttactatatg gaaaagtgca tgggaaatat ttaaaacaag ttggcttatc ggagtctctc
    10921 cgaaaaatgt agtatcttat gcacagtcaa ttattccaga tggatatatt gcgaaagtag
    10981 gaattgccat tcataatgca tacttgaatg tattaacatc gacaggtatt ctaggaataa
    11041 ttcctttcat ggctttttta ataaagagtt ttgtgctgaa tgtttatcga atcatctata
    11101 ataaatgcat tggtaaagat tatcattttg tttactgttt agttatttta tcttatgcac
    11161 tatacgcagc tcttaacaat gaattagtct atgaaaacac tgtaggaacg tttgtttttt
    11221 ggctattttt aggaagagtt aatagcaaaa ataattctag ctatttttag taataaattt
    11281 tatcttgaaa agaggagaaa aaatgttgaa ttacttgatt accggtggcg ccggcttcat
    11341 tggctcgacg ctcgcgaatt atctaggaaa agaaaacaat gtagttgtga tcgatgattt
    11401 atcgatgggg aaaaaagaga atctggatga atcgaagcac atcacgttta ttgaagggga
    11461 tgtcgctgac aaaaatttga tggaaaaggt catgaaagaa taccatttcg attatatttt
    11521 ccatctagct gctgtagcta gtgtggcaga ttctgtagaa cgtcctctag aaactcatcg
    11581 tgtaaatttt gacagtgcgc ttttattgct tgaattggta cgaaaatatc aatctggttt
    11641 aaaacgattg gtatttagtt catcagctgc agtttatggc gatgaaccaa cgttgccaaa
    11701 aaaagaagaa tcggtcatcc gtcctttaac accatatgcc atcgataagt ttgcagcaga
    11761 acaatatgtt ttggattact gtcatttata tgatgttccg actagtgctg tccgattttt
    11821 taacgtttat ggtccaaatc aaaatcctaa ctctccatat agcggagtta tttcgattct
    11881 agtggaccga tacaaaaaac aattggcagg agaaaaaaca gaatttactt tatttggtga
    11941 tggtagccaa tctagagact tcgtttatat agaagatgtt atacaagcac ttttacttgt
    12001 tgctaaggaa gaaaaagctt taggacagca attcaatgtc ggtacaggaa aaagcactac
    12061 gctacttgaa ttgattcatt caattgatca aatcttagga acagagctag cgcttaaata
    12121 tgaagcggag cgttcagggg atattcgtga ttctttagcg gatatttcaa agatccgttc
    12181 tttaggttat caacccaaat ttgatatatt gaacggaatg gaacgttatt taaagacaga
    12241 aatcgattga aacaaaaaac cagcatcctg ctggtttttt tgtctcgact tagcttttta
    12301 aattaacacc ttccatcagt tcgtaaatct gatttcttaa atcagtggcc ggcaatttga
    12361 tgtttttatc agattggata ttactttcca tgacgattgc atcttttgtg tcttttttca
    12421 tcgccgctac tgcatggaat cgattgatat ttccctgagc aaggatataa tcatttccac
    12481 tgtaaacacc gccgctgtaa ggatgtttat caccattatt ttgccacaat gagaaaagta
    12541 gttcttttgg tataatatcg ccagacagaa cactggtaaa gaatttgttc aagtcataaa
    12601 cagacatact tatatttcct gtgcctaatt catttcggat gtctgtttca ggctcgacca
    12661 atgcttttga ataatcgtca gttgcagaca tttggtaaga tacagcatgc tgcggggaat
    12721 tttttacatt ttcataaaaa tctgtatgtt ctagatggag tggccgaatg atttcttttt
    12781 ttaaaagagt ttcataaggc tgattcatta gtttgatcaa tacccctgta agcaatgtat
    12841 aatttaatgg ttcataatga tacgtatcat aaccagtaaa tttcaaatga tgaagggcaa
    12901 actgaatgat ctcactatct gacataggtt tttttggaga agcggttcga tgaagaccag
    12961 agcgcatgta aagcatattt ttgattgaga tttgctgact tccaggaatc tgaggataaa
    13021 attcagatag ctttgtgtca aaagttatct tgccagattg aatttgtttt aggataagta
    13081 aagcagtcat cgctttttgg atcgaaccga tttgatagta aagagaagga gaattcgatt
    13141 cttttatgcg tagatttgcg tacccatatc ctttttctaa tatcactcga ttatttttgc
    13201 gtacataaat cgaaccgata taatctgatt tttgcagtaa ttgatcaatt ttgctggcaa
    13261 gcatctgctc attagatgtt aaattggaag caagttgtgc gggttccgtt ttataaattt
    13321 gtggttgagg ttgttttgtt aattgccatc ctgtaatgat gcctgttgaa aagaagctga
    13381 cagccagcaa caaaactgcg agaaaagaaa gagagatctg ctgttttttt tgatgttttc
    13441 cttttgccat attaaatcct tcctatccat ttttaactat ttttcattgt aatcctcaaa
    13501 aagagcattt gccacttaca attttgacat aatatttggt aaaataattc acggcagtag
    13561 aaatttcatg tataataaac agagttacga agatgatagt aaggaggagt tgttttgtca
    13621 ggaaacaaac aacacccaag caaagacaaa aaagaagcca gtaaggcagc tacagcagat
    13681 ataatcgaca agcggagaaa tctgcgtaaa aaagaagata agatcgtgag gaagatcatt
    13741 ttagtgatcg ctcttacatt attgattatt ggcggatttc tcgggtttac cgtatatcgt
    13801 tatgtagata gcgggttgaa gcctttagat aaatcggacg accaattagt ccaagtggaa
    13861 atcccaagcg gctcttctaa taagcagatt ggcgaaattt tggagaaaga caatattatt
    13921 aaaagtggga ttgttttcaa ttattataca aaatttaaaa acttaactgg ctttcaagct
    13981 ggttattatc agttagcgcc taatatgact cttgatgaga ttggcaagca gttgcaagaa
    14041 ggcggcacat ctgagccaac aaaagttgca gatgggaaaa ttgccattcc agaaggctac
    14101 gacatcgatc agattgctga gcgggtagcg aaggtaactg gtaaagacaa gaaagaattt
    14161 ttagatttag taaatgatga gactttcttt aacgagttgt atcaaaaatt cccagaattg
    14221 ttggaaagtg cctctaaagc tgagaacaca aaataccgtt tggaaggcta cttattccca
    14281 gctacttatg attactacac gagtacttcg cttaaggatc ttgtgattga gatggtgaac
    14341 aaaacaaata cggtcatgca aaactattat tcagctatca aacagaaaaa tttgactgta
    14401 caagaagttt taactttggc ttctctagtt gaaaaagaag gcgtaaaaga aaatgatcgt
    14461 aaaaatattg cacaagtctt ctttaaccga atcaaggcaa atatgccact tcagtcagat
    14521 atctctgttt tatatgcatt aggagaacat aaagaattgg tgacgtatga agatacagct
    14581 gtagattcac catacaattt gtataccaat accggctatg ggcctggtcc ttttgacaat
    14641 ccaagcgaag aggcaatcaa ggcagtatta gaaccagcag aaaatgacta ttattatttc
    14701 gtagcagata cgagcactgg aaatgtttat ttcgctaaaa cgtatgaaga acatatggaa
    14761 ctagtgcaaa aatatgtaaa taattcttag aaaaacaggg gctagtcatt gatcattttt
    14821 agaaaaacat ttacatttta agaaaagcgt ggtaatcttt tttggactat attcctcaaa
    14881 agattacctt ttgcggtatt ttatcgaaaa aaggagacgt tacacatggt agagaaagtt
    14941 tatccaatga ctctagaagg taaagaaaaa ttagaaaaag aattagaaga actaaaaaca
    15001 gttaaacgcg gagaaatcat tgaacgaatc aaaatcgctc gcggtttcgg agatctttcc
    15061 gaaaactccg aatacgaatc agctaaagat gaacaagcat ttgttgaagg aagaatcaca
    15121 acaattgaaa atatgatccg ttttgcacaa atcatcgata atgacggcgt agatgcagat
    15181 gaggtatcga tcggtaaaac agttacgttc atcgagttgc ctgatggaga tgaagaagag
    15241 tacacgattg tcggaagtgc tgaagcagac ccgttttctg gaaagatttc caatgattct
    15301 cctatcgcgc aagcattgat tggcaaacgt aaaaatgatg aagtaaccat tgctacacca
    15361 ggtggcgata tgttagttaa aatcgtcaaa gtagaacaag cgtagtctga ctgaaagatc
    15421 tagagagttc atcttactga tgacgcactc tagatctttt ctctttgagt attgcaggtt
    15481 tcactgaacg atcttacatc taaagtccta tagccaacag tcaaaaaaat aggtatgatg
    15541 aaatgagaat gtgtcaggag ggagaaaaag cgatgaatag ttcttggcgt ttttttgtgg
    15601 tagtcgaagc actgctgctg ttatttgctg tttggcaaat cgtaaacaat actggacttt
    15661 tgcttttagt aatattcggt attttcaata tatatctagc tatgcgcaaa tatcctcgta
    15721 ctaaatttca aaattttcaa ttgatcttag ggagcttggt catttttttt agcttagtca
    15781 acagtcctgc tttatggatg atggttgtat tggccgtttt atttatcggg ctgaaaggtg
    15841 tagagatttc aggaatagat ttgacaaaaa atgctttttg gcgaaaaaaa cagatcatga
    15901 tggtccaaac agagcaatta aaaacacata ataatgagcg taaaagacag caattatttg
    15961 gtaaccaacg tattggaaac gacgtctatg aatgggatga tatcaacatt gccatcattt
    16021 ctggtgatac tatcatcgat ttgggcaata cacttttgcc aaaagatgat aatattgtga
    16081 ttgtaagaaa agggataggc agaacacgga tcttagtacc cctgggagtg gctattcgtt
    16141 tagagcatgc gacattagta ggaaatgtct tgtttgaaga agagcagttt tccttaaaaa
    16201 acgaacagat caaaatctgc agcagtgatt atgatgaaaa tcctcgcaga ttgaagatca
    16261 ttaccaatac tttggttgga gatgtcgagg tgatacgaat atgatgggaa gaatatccaa
    16321 agcaatgcta gctgtttatt cggggattgc ggctttcctt attattctat tttcactttt
    16381 cacttatttt tatgccagta accaaagtca ttggtgggga gaattgctgc gtgcgcgttt
    16441 attatacgtt ccgcttatct tccatttgat ggcaatttca ttaggtgtag gattgatcgt
    16501 atttctattg ttatcactta ttcaaaaggc aaaatacggg aaaatcgaag aaaagcttcg
    16561 tgcactttct tctggcaatt atgaatccaa acttttgcat cagccgatcc caagcgcgtc
    16621 ggatgatctg tacatcaaag atattgatat ggaaattact aaaataaaag aaaaaatgat
    16681 cgaagtatcc agtgaattac agattatgac tagccgtcct caatatgtag atggacaaac
    16741 caaagaagag attttaaaat tagaaaggca tcgattagct cgtgagcttc atgattcagt
    16801 ttcacagcaa ttatttgcag cgatgatgat gatgtcggca ttgacggagc aagcagaaaa
    16861 aagtgagaca ccagaaatgt tccgtaagca gttgaaaatg gtggcagaga tcatcaacgc
    16921 ttcccagtct gagatgcgtg cgctgcttct tcatctgcgt ccagtcaatt tagaagaaaa
    16981 aagtttaaaa caaggcattg agcagttatt gaaggaattg cagaataaaa tccagatttc
    17041 gctaaaatgg gaggtagaag atgtaaaatt aactagttcc attgaggatc acttgttccg
    17101 aatcgttcaa gaattgttat caaacacatt aagacatgct aaggctaatg aattagaagt
    17161 ctatttgcat aaaatagata acaatctttt attacgtatc attgacgacg ggacaggatt
    17221 taatatgaat gaaaccaaaa cgggaagtta tggattgaac aatatcaaag aacgagtagc
    17281 tggtattggt ggaacagtaa aaatcattag ttttaaaggg caaggtacga gcgtggagac
    17341 caaggtccct ttgatgaagg aggcatagat aaagatgata aaagttttat tagtagatga
    17401 ccatgaaatg gtacgcttag gcgtctcttc ttatttatct atccaagaag acattgaagt
    17461 gattggagaa gctgaaaatg gacgtcaagg ctatgaaaag gcgatggcac ttcgaccgga
    17521 tgtcatttta atggatctag tcatggaaga aatggatggc atcgaatcaa caaaagcaat
    17581 cttaaaagat tggccaaaag ccaaaatcat tatcgtcaca agttttattg atgatgaaaa
    17641 agtttatcct gcaattgaag caggagcagc aggatatttg ttgaagacgt ctacagcaca
    17701 tgaaatagct gatgctataa gggctacgca acgcggcgag cgagtactag aacctgaagt
    17761 gacaacaaaa atgatggaaa aaatgagtcg gcgaaatgat ccagtattgc atgaagaatt
    17821 aacgaatcga gaaaatgaaa ttttgatgct gatttctgaa gggaaaagta atcaggaaat
    17881 cgcggatgaa ttgtttatca cactgaaaac agtcaaaacg catgtgtcga atatattagc
    17941 taagttagag gtagaagacc gaactcaagc agctatctat gcgtttaaac atggtttggt
    18001 gaaataaaaa cgatgataaa gaggataatc aaaagctgag aaaataacta ttatttttct
    18061 tggctttttt acaataatga tgcttgcttt tgtttttgga aaggctttgt tatactgaga
    18121 aaagaagata ctaaaggagg aaaatggtga aacaaaattt tgcaattgta ggccttggac
    18181 gatttggcgg aagcatctgc cgtacactga tcgaagctgg acaagaagta ctggctattg
    18241 acagtaatga agatcgagtc aatgaatata tgaatatagc cacccatgct gttgtggcaa
    18301 atgcacagga tgagatgaca cttcgttcat taggtataag aaatttcgat catgtaattg
    18361 tcgctattgg agaagatatc caagccagca tcttagttac tctgatggta aaggaaatgg
    18421 gcgtaccgaa tattttagca aaagcccaaa atgagtacca tgcccgtgta ctagagaaga
    18481 tcggagcaga tcgtgtcgta caccctgagc gagacatggg gatacggatt gcacataact
    18541 tagtatcaaa gaatattcta gactacttag agctgtcaga taaatattct ttagcagaaa
    18601 tccgagtctc caatcctaaa tttttcaaca aaacattagc tgaattaaat ttcaggcaac
    18661 gttttgactt aacagtagtc gccatacgaa gagtagatca aacggttatc gcttctcctg
    18721 cagcagatga atatgttcgt gaaaatgata atctactggt tattggagag acaggcgatg
    18781 tggatattct agacgataag atgaatcaat agaaagaaaa gagaaagtag gttgttggga
    18841 tgaaattaac ggtaacgcca aaagcacaaa agtggtttga ctcagaaatt gatctgccag
    18901 aaacttacgg aatacgtttt tttggaaaag tctacggcaa aacagaggtt catgatggtt
    18961 tttcgattgg aatgtcagtt gaacagccag aacatcctgt aaagaaagtg gaaatggatg
    19021 ggacactttt ttttatcgag gaagcagatg aatggttctt taaaggatat gatttacttg
    19081 ttgattatga tcccaacctg gaggagccaa cctatcactt taaaaaacaa taaaaaaaga
    19141 gagggtgaca caatttttgt caccttctct tttttctttt gaaaatattg
//
LOCUS       DACGLI010000055        18969 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.057, whole genome shotgun sequence.
ACCESSION   DACGLI010000055 DACGLI010000000
VERSION     DACGLI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.057"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(342..2312)
                     /locus_tag="IXT22_002218"
     CDS             complement(342..2312)
                     /locus_tag="IXT22_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863554.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2327..3193)
                     /locus_tag="IXT22_002219"
     CDS             complement(2327..3193)
                     /locus_tag="IXT22_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863555.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3183..3416)
                     /locus_tag="IXT22_002220"
     CDS             complement(3183..3416)
                     /locus_tag="IXT22_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4863556.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3428..5584)
                     /locus_tag="IXT22_002221"
     CDS             complement(3428..5584)
                     /locus_tag="IXT22_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863557.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5604..5825)
                     /locus_tag="IXT22_002222"
     CDS             complement(5604..5825)
                     /locus_tag="IXT22_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863558.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            complement(5935..6273)
                     /locus_tag="IXT22_002223"
     CDS             complement(5935..6273)
                     /locus_tag="IXT22_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863559.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            complement(6673..10314)
                     /locus_tag="IXT22_002224"
     CDS             complement(6673..10314)
                     /locus_tag="IXT22_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863560.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPAPDN
                     QENNQETVINKSVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGELLKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10317..12266)
                     /locus_tag="IXT22_002225"
     CDS             complement(10317..12266)
                     /locus_tag="IXT22_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4863561.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12308..13366)
                     /locus_tag="IXT22_002226"
     CDS             complement(12308..13366)
                     /locus_tag="IXT22_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAQ4863562.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13485..13940)
                     /locus_tag="IXT22_002227"
     CDS             complement(13485..13940)
                     /locus_tag="IXT22_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863563.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(14524..15327)
                     /locus_tag="IXT22_002228"
     CDS             complement(14524..15327)
                     /locus_tag="IXT22_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4863564.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16307..17530
                     /locus_tag="IXT22_002229"
     CDS             16307..17530
                     /locus_tag="IXT22_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4863565.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            17565..18332
                     /locus_tag="IXT22_002230"
     CDS             17565..18332
                     /locus_tag="IXT22_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4863566.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            18524..18922
                     /locus_tag="IXT22_002231"
     CDS             18524..18922
                     /locus_tag="IXT22_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4863567.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
BASE COUNT         5732 a         3621 c         2748 g         6868 t
ORIGIN      
        1 aaactctcgc tttttcttca tcagtaaagt ttttatacaa ctgattacaa taatgaggtt
       61 tttgaagttt ctgaatacct atactaactt caaatccttc ttcatgttga attaggatta
      121 cttctgtgtc tctacctaga aatattcgat ctaaaatttt tatgtttggt ttcattattt
      181 aacctccact ataattattt cactcagtaa ggtttcactt tatgaaattt ctatagttct
      241 cttttcacaa aacgtaccat gttctctaag actgttttta gtctcaaata tacatgtttt
      301 ttcttatcct ttccttatac actcaaaatc aaagataaaa cttaaagaat aaactctcca
      361 ataacaaaat tattagtcag atccactggt ctcctgatct gaaatttatt acttcttcct
      421 gttgtcaaat actgtctcaa atcaacagaa agtttttgat catcttctcc ttttctagca
      481 ggagcaactt ttttttcata cttcattaac tctccactgg tcatctttcc aatgatagtg
      541 taattaaaat cactttcaaa actttggtaa atttttccat ctgtattgaa tatatcagct
      601 gtttcaatat cttctttgta ttcattgtct tctcctgaac cgattgtatc aaatagaaag
      661 gcaagacgaa ttccatcttc ttcaagcatt gttaatcttt ttttaattag cccaacggtt
      721 tcaatagata acttatcgaa gccgtgaatc ataacaatat catctttttt tgcttgtgat
      781 gtgatgaaat caaaggtatt taaaaattga gcttccataa cattggtttc tgctcttaga
      841 tcacctaagt tatagtaaaa ctgtaatttg tcacttttac cgatttcttt cagtgtcgtt
      901 ctttgattaa acatcctaga gaagctgtct aatgctgttc tcaatgtgtc ttttaataca
      961 ataatacgat cgacttcttt ttcagtacca gattttttgg cttttgtttc agcattagtc
     1021 aaatagctaa taaaatcccc aagaactggc attgtatcac tactgttcac caaaagtttt
     1081 gaacgttctt cataattaat atcccaaagt ttctgactta tataaaagtt acctaattct
     1141 tttttcaata aaactctagt tgcagaatct aatgttctgc ctgctaacaa ataaaaaatc
     1201 tgagttagtt tatcgagatt ccgtctatat aaatcaccaa tgtccttttg attaccaaaa
     1261 agctccaaag agttaagacc ttcttcagcc aaattaacct tttctattac actgtttaac
     1321 gaaggtttgg caacaaatgt tctaccagtt ggatcaccaa agtaatcaaa tttatttaag
     1381 acaatatgaa aagttcgttt atgatttgcc attgcattat tagcaatcaa ttgcccccaa
     1441 agtgatgatg ctgagatttt ttcatcatag cctttaattg tagcgttttt gtgtgatgcc
     1501 actaaaactt tacttgtaaa agaatcatcc agtgccataa aagctacacc acttgcgtag
     1561 ctagtagaca tagtgccgat agcccatcca ttcgcatcat ctaaaccttt gcgaattgca
     1621 tgatcatttc ctgcaaaatc cgaactcata gacgtatact catagacatt cccgattggt
     1681 tcacttaaaa gtctatcaaa cagatcacgt tgatctcctc catatgacat aagctttaat
     1741 ccatacattt tttcatcata caaccgttgg agtttaatta gctgttcgct gattttatta
     1801 ggagaatcgg atactaatag gatttctagc ttccaatcaa taattttatt tgccatgctg
     1861 tctagtaaag atgctgtatt caaatccata atccgcataa cagttttgct aatttcagca
     1921 tctgaatttt ttccttctaa attattttca taactattcg ttgatccccc aacattctcg
     1981 tgcattattt cttgttgatc tttttgtgac actggcttat ctgcttcaat tagataggct
     2041 tttacccctt ctactctcac ttcaggaata gctttaacca tccaaccaaa tccataattt
     2101 ctattcattc cataagtatt cactaatttc acaattgttc cccaccgctt acctgtccta
     2161 atgtaagatg gtgtaaattg ataaccaact aaagatgtta aatcactaac aaaggtatta
     2221 ttcactacct ttgaatttct agttttttgt tcttttttag tttttctctt ttttttgaaa
     2281 tttaatagtt gtgatctacc cataatttcc atttaatctc tcacctctat ttcagtgcat
     2341 aaatatcaga taatatttct tttgtttgtt tagctgacaa ctgagtgaca ctataataaa
     2401 gtcctctact cgtatagttt tctaaacgtt ccacaccttc atccaatacc atcttagatt
     2461 gagatttcaa gataagatat tggattactg ttgttttcac accatcaata tattctgata
     2521 caaatcgttc ttgctgatct attatgtcaa agactgcttt gttactcctt gcatttcgtt
     2581 tttgtatttt catatttcga gtttgtcttt ccgtattctg aggttgagat gaagtgattt
     2641 tgatttcagc taaggaacga tctctggtat tttgatattg tattgatttc gattcctgag
     2701 ccataacttc ttctggaaaa gcggttagtg atgtagcccc atctagattg aacattaatg
     2761 ctacactccc atctcgatat acgattgttc catcttgttt cacttttaaa atctctgtgc
     2821 ctcgaaatgg tttctttttc cccatagata ctcttgctga attaactact gatttgaaca
     2881 gtctaataga accagaaatc aatgaaccac tagatggatc aataaacata tactggctaa
     2941 ttagaataag aaatccaatt atcattaata acgttggaac aaaaataaat ttcagtttaa
     3001 tcgtatcaga aactaagtaa acaattgatc caagaacaac gactgcaaca actatagctg
     3061 atacaattaa tctttttgct gtaacagaat aggtgctatt gacatgcttt tcaagccatt
     3121 caactctgac aattgtttca gaaggttttt gatgtaagtt atgtttaaat ccatagtttg
     3181 agttatctgc catcagaaat acttcctttc acgttcaact tacggtaaac acctacagtt
     3241 atcactattg caacaataag caagccaatt aaagatattg acttgctcat tgtctcgttc
     3301 gtttgtggta gttcatttac ctgatacacg agctgtgctt cctgtaagtg ctgagaagag
     3361 gtcatgtttt cttgattgtt ttgaattact ggataaacta ttttttcttc tcgcataata
     3421 gccctcctta gttattatca gataagtgag cttgaatttt gtactgattt ccgtctggag
     3481 ttttcacaac tgctttttct ccatcaatag aaatcacttc agccttagtt gttttcccat
     3541 caatactgat gacaacatct ttcccaactt tgaactctgt agttggtgtt gcttcatagc
     3601 tactatttgt tgaagcagag ttcgtatttg tcccaatcga attttccact ctcgaaatag
     3661 atgtttgagt ttgagcctgt gcttgttgat tattatgact aataaagtag gacgatccca
     3721 agatcgttcc gcaagccatt gcagcgacag aaatgatagt agccatcttt ttacttgtaa
     3781 aatcacgttt tgaacttgat tgattttctg tagcaactgc taatgatttc gttttttctg
     3841 ccatttgagc tagatcactt cgggaacgag ataagtcttc tcttaaagct tcactttgtt
     3901 ctgccaactt ttcgctattt aatttataac cctctgctaa atctttgacc tctttcattc
     3961 gatctttata ttcttcgata gttttttgtt gctctacaag ttttgtttct aattctttcg
     4021 tgttgttagc tacctgcttt tcaacttctt ctttgttcgc aaaatatttg acaaccacat
     4081 ctgttgtttt ctcttttgta tcatggaact cagcttcatt ttctgacttt gttttttcga
     4141 caatctctaa agttttttct tgcacgtctg ttaatgattt ttcaatttct ggtttcaatg
     4201 aattgataat tcgttccacc acaacttctt ttgcttcttg gctttgtttc aatgcatcgt
     4261 ttttaataga ttcaattgct tcttggtact gttgatcaag actttcttca gttgcttttc
     4321 tatattcatc ttcttgttgt ttaacttctg gtaaatgctc agcatcatac cgttgctcta
     4381 gtttctttag ttcagcatcc aaataagcct gtttcgccat atcataatct ttacgaatga
     4441 tattggattt ttccatcact aaatcatcaa ttttagatgc ttctgcttcg tagctctctt
     4501 tagcaaccga tagtgtattt gtaaactgat tttgaccatt taatgaggtt gcttcctcta
     4561 tccgcaaaag ctcatcagct aacatttgct ttcctttgag gatcaattgc tccttcgtct
     4621 tatttaattc actgttgatt ttattattag caatagagat gcgagcgttc atactctctt
     4681 tagctaaaaa cagcaatggt ttcaactcag gtatggatag catctcctcg tttaaatcga
     4741 cagggtcatt aatctcatct aaaactacag gttgaaattt gtcagcaatg atctgttcaa
     4801 aatttttttc taaaaaatca gcatctaagt ttttcggtac atcactttca gatgtgattt
     4861 tttcagcttc ataaacataa ttttctttgt cactttggga ttcgggtttt tcatcaattt
     4921 ttggttgttg gtaggtttct gtttgtattt gtgtttcttc tatgcttact tcttggtttt
     4981 ctgcttcggt tggtttgtta tcatccacaa aaagagcttc tttttcatct ggtacatttt
     5041 ctgctacggc ttcaaattca acttcttcag aagagttgaa ggtctcagca attcgttcta
     5101 atccattagt agctacttct aattgctcta ctgcgctata gaagtctgta gcttcttcaa
     5161 cttctgattc aaacacatta ggatcatccg gaataactaa taattgacca ctactatcca
     5221 taaaacggac acctgctaat agcttctctt taaatttttc tggtagatca gctacataat
     5281 tcaaacttga cttcaataga acgacatact tctcagaatc gagaatagca tcatcctcat
     5341 ctataactcc ctcactgttg agcttttgta catcttcaat taccatataa tttttctttg
     5401 gtaaatcttt ggtcagcaac gcatcgaatt ctttccatac ctttgcttta gctttttttg
     5461 ccttcgcttc tttttcttct tttttgtaca cttcgagtaa ttgtggcttc aaagagagtg
     5521 caactacagg aactgtttct gccacataat taatagattc ggtaatatct ttgaattttg
     5581 ccattattgt aaaactcctt ttttcagtca atagttcttt tctgtttatc tagcatatat
     5641 acatatgctt tttcgaattt aataagcgtt tcaagtctgg ctttttcaat ctttttactc
     5701 ccatttcgat aatcatagaa ctggttaaca ttcatattca ttatctttgc cagttcggta
     5761 cctttcagac tgctcattaa tacttcgttg gcgtgagcta acattttttc tctatcaaaa
     5821 accatcttac atttactttc ttccctcact tctaaactac gcttggagcg tagttttttg
     5881 gtaaaaagta aattgaacaa atcggcatat tatccaaatt tgttcaattc acttttaacc
     5941 taacagttca ttttttggaa attttgaaac tagatagata ccaacaactg gaataagtgc
     6001 tgatatgata ttagcttttt ggttcaaatc attacctgtt ttagtaccca ttgtgtaaag
     6061 cataacggtt gtaattacag gaataataaa gattgcaata atcgccccaa catattttaa
     6121 tccatctccc cattttgcat caccaaaaaa tttcattgca gtgaatcctg gtttcaacga
     6181 aaaaacgaat gccaagaaat acaaaacaac ttgtactaaa gttttcatat caggcgtcat
     6241 tccgctaacc aaatttttaa tagaatcgaa catataaaaa cctccttttt aatattttta
     6301 ataagttaat tatatcatcg acaaatctta tttgttcact tgtcaatgat ctaactaaga
     6361 aaaagacgtc tcgatattta catctttatg ttatcataat aacataaatt ttcgatgatt
     6421 aaaagagatt ttccattaaa ttatttcact ttttttattg gctaaaaatg ctggtttatc
     6481 aagtttttgt ttatataata attctgttct ttaccagcat aagccctttt taattataca
     6541 actttgaaca gtaaatattt aattcattta tagacaattt aaaataattt ttttgcataa
     6601 atagaaattt tccttgacat cttcagttag aaatcaaagt aaaaagaagg agcaaatcaa
     6661 tgctccttct ttttactcgt cttcagactt attttcagtt gatttttgat taccgtattt
     6721 tacaatatag tccttgactg acatggtaga tttcttcact actttaccag ttttggatgc
     6781 tcctgtagca gtagccttgg caaccttagc cgttccttta cctattttaa tagcttcgtt
     6841 tttagcttca taggttatcc ctgctagact accttttgga gcttttgcta aagctttatc
     6901 tgctgaggtg taaacatttt taccagtttt tgatagatat tcaacggctg atttagctgt
     6961 tgatggtttc ttggttgatt gattagattt ccctgaatta tctgaagtag atttagaatt
     7021 atttgttcta ttatttttat ttgtcagttc aggttctcta attgattgat tgtctttcga
     7081 cattcctgat ccaatatttg tttcatattt atctgtttga ttaacattag gagtaggaat
     7141 gaactttttc ttcacatctg attgttcttt atccgtttct tttgttagcg attctctgtc
     7201 tttaagtgct gtgtcattcc gaatagcact attatcaaag ttgctgttaa gctctcttga
     7261 ctgactttca ccagatgctc catctcctaa ttcccgatgc actctgtctg acacgtcctc
     7321 accactcatt tcattcctca gttcttgatg agtttgatct aaagtaatct cgtcatcttc
     7381 attctcagga attgcaacag caattggcgt atgtcgttgt tgttcgagtt ctctatttcg
     7441 atctgccaca agcgcatctc tcgtctcaat gatattccca tcctcatcga ctaaatctcc
     7501 attcacatta tatccatcgc tgtgtttacc aagtttatta ccaaactcat caacaagatt
     7561 tccatcttca tcaactaaac gccctttttc gtcaactaaa cgtccgttac tatcctgacc
     7621 aaaatcacca tttagcaacc tgcgtccatt ttcgtcaaca agatttccat cttcatcgac
     7681 taagcgacct ttttcatcaa ttaaacgtcc ttcgctatcc ataccaatat taccatcttc
     7741 actatcttcc aatggtttac cattagtatc tataaggttt ccatcttcat cgaccaaacg
     7801 ccctttttcg tcaataaagt tgcctttagc atctttaccg tatttactat cttttaataa
     7861 ttcaccattt tcatcgacaa agtttccgtt ttcatcaacc atacgtccta aatgatcaat
     7921 atattgttgg gagttattac gtagttgatc ttgacgaact aaatctttga aagaggtatt
     7981 attgattgtt gaaccaactc cgccaccgtt gaatgacatt ccttctggtg tttcaggaat
     8041 tactttatca gcaatggact tagcatcagc attgctatct cccatattgt tcaaacgttc
     8101 agccattttt tgcgctccaa ctgctccaag acctcctgca accatatctt ttactgagct
     8161 gttgccacca tcataatagg gatttttagc tccttggctt ttcttgattg ctttagaaac
     8221 gccgtccaca actcgcacag catcatttct attaccaaat aataacttag cacgttcatc
     8281 aaacccaaac gctacttcaa gtggtaagcc aataagcata ttaatcaaat tatttacttt
     8341 ttcgcctttt ttaaagacta aaagatatcc tacacctaaa atcatagcag atcgaacaat
     8401 atttgctacg ccatcgccaa ctaatgtatt aggaatgaat cccacagcag tatcaccaaa
     8461 tgcacgaata aaagtaatca gaaagatagg taattgtagt ccgatcagag atgttgtaac
     8521 aacacctaat gaaattgcca tcacacctgc tcctgatgca agtgatcctg ttagaactac
     8581 ttcccaaatc cgaataaatt cacgtttaaa tgctttcacg atattcacat tgaacatcgc
     8641 ccaagcacat gctaagtaaa gaactgctaa aacgattgat tcagcgttca tcgctagcca
     8701 cgagccaaac ttacccatcg ctccatgacc aactaaggat gctgtacgcc attctgtttt
     8761 tactgttgac atattcttag cactgccttg aattcctgaa ggagcgatat tatacgcata
     8821 aaacttagct cctgatgtat caagtgccga ttggagcaat aaagctaccg actgtgtgct
     8881 aaaagttgca ttgttagcaa cgccccaagg ttgagtagca tcaaagttat gcgctgttcc
     8941 ttttccatca ggcttgcgat tgtcgtctgt cacattttga tttgctgacc aaatatatcc
     9001 atttaaattg gttggtttct taattgcact tccttctttt ccatccccta aattatagcc
     9061 tgtccaaaca gcaggcgctc ttcccatata agcatcattt tcggcgacat taacatcacc
     9121 ggcataagta ttaatattga aagtatcatt cgatgaccat tcttttaata gagccatacc
     9181 gactgaatta gaatctagat cattattttg tctggcataa ctgctagtat tgatcgctct
     9241 tatcattgca gattttttag atggttcata atctgtatca acgaacttga tttcggatgt
     9301 aggctttccg tcaggtacat caccaccagt atcagatgat ggagcaagat tttgagtaga
     9361 agcccaaagt cttgtgttaa tgatgtagtc agaaacaaca tttgttggta tatctccatc
     9421 tttttttgct gactggatgc cgttgatata aactcccaat agcgatcctg ccactggtaa
     9481 gaatataaac aatacaaaaa tacgaacaat ccatttttca agtactggtg ataatccctt
     9541 cgagttaaca ccatctttcg acaataattt cattccttga taacctagta ttgctgtgaa
     9601 aaagagcata gataagcttg ctatcgcttt aaataattca ttatttaatc ccaaattgtt
     9661 aagcaagcta gttaatgctt tagataccgg attagataca tccgatccac cttctcccca
     9721 ccccataaga gaaaatatat tcatactcat gaaaaatttt ccaaggagtt catttatgga
     9781 ttcagcaata ttagaaagga ttaaactaat tgatccgata aaactaccaa tcgtcctacc
     9841 aatacttcct agaatggatg atgcttgact ggcaatagca tttcctgaga ctgtttcaat
     9901 atatccatag taactataag ttgctagagt agatgctagt tgtgtacctg cattcccccc
     9961 tgcaatcgaa ttaccttgtt tagaaatatc agaataagga aaatcagcac tgataccacc
    10021 ttgtcctaac aaattcattt gtccagtttt agcagcacta tcattgactt ctttatctcc
    10081 catcaagata cgagcatata gtgtccacat cccttgttct gccggtttac tttccgcata
    10141 agcaacgctc ttatttataa ctgtttcttg attgttttct tgattgtcag gagctggatc
    10201 attcattcca aatggagcgc ctaaagttac tgctaatacc cctccaataa ctagacctct
    10261 tacgacccat cgttttattc taaggttttg tagtaaatat ttcttgaatt tcatagctac
    10321 gcccctccaa tcgaaaatac aatcttgttt tctttacttt cagcaacgga aggctttgca
    10381 ataatttcag cattagaatc accttttcct tcaaacgctc cagcttcact caacttaaca
    10441 tcgaatattt ttgcgtttgg ataagtaatt attgcttcag taatcgcttc ttcaaactca
    10501 gattcaacta aatgcaagat attccttgca ccccctgatt tagaatcctc ttgtgaagcc
    10561 atgtcaaaaa ctaagtgcat ggagagatcg tctgcataaa aattttgacc atatactctt
    10621 tctttcctag gtggaagacg taagtctata tttaaatgtt ttcgtactaa ttcagcactc
    10681 ttcaacattt cattataagc aatttccaga agagtttgtt cggataaagc ccaaaatgga
    10741 actattcgtc caaatcggtt aataacttca ggctttagac cttcaccaat caaggcttgt
    10801 ttgatccctg atgcgacttt tcggtattct ctttttagtt cagtgctgta ttcattagaa
    10861 ttttccttgt ttgtaacacg agatagtgag ctatatcggt ttaacgaatc gaacatctcc
    10921 gcacctgcat ttgttgtcgc aaataaaatt gtatttgaca atgaaacggt gtcgtgaact
    10981 tctcgatcat cccatcctct ttcagtaaaa cttatcctac cttcatctaa aattgataaa
    11041 aaggcatcga gtgtttctac accagctttc tcatattcat cacacacaat aatcgcagaa
    11101 ggatcatgcc ttacatgagt acctatgagt cgtctaaaac gcattgcatc atctttggtt
    11161 ttgtaatccg gcatattaac taagagaact ttattttcat cgccataaag tcctcttgcc
    11221 acggctttag ccattgcagt tttaccgacc cctgttgatc ctgtaaacag agcagttgct
    11281 tttggttgct ttcgaccttt aaaacgatca aatccaagct tcatacgttt aaacaacatt
    11341 gttatagtat aaactgctaa cggttgtcct tttatggact ttaattcctc ttgaagtttt
    11401 tccatatcaa aatcagaatc tagctgaata ttatacttac caaatatttg caatagactt
    11461 tctcgattat aagcatttcc gtctactcga tcttttgcaa tcaaatcctc cattacagca
    11521 attgatttag ccggttcgga caaatcctca cgataaagtt tgtttgcttg tacgatttct
    11581 tgaagtaatt catcaggaat cctttgcgat aatctaaaag aagcctgagg atcatcttta
    11641 acagaggatg tatttagcca ttgtctcaaa atatcgacga caacatcgct ttttagttca
    11701 ttcaattcta acggttgtag ccgtctccct aaggcatcat ctcttttgat atagttttca
    11761 tattcttttc ttgtagtagc ggtaatcatt tgaagtgatt catttgctaa cggttctttt
    11821 agcgaatcac ccccaatttt attgccactc ccaaaagagc taacaacttt atgaaactcg
    11881 tcaatgaaga ggacaaattc attatctttg tcctcagctt ttaaaattcg ctcatattct
    11941 ttcaatcttg gaattaatgt ttctaaacgt gtttggagga catcatctcc cccaacacgc
    12001 aattgtccga ttgataattt atatacttgt actttctttc catcttgtcg ctgtctttca
    12061 gcccattcac ttgcaagtgc tgttttacct gttccggctt cacctaacaa gatagcttgc
    12121 ggtgtttccg gtctattcaa gatcagtgac aactcatgga gttcgtcatc acgtcccact
    12181 aacttatgtt ttggtggttt cattggtgtg agagcatgat taaattcggt ttgaatattc
    12241 ttaaaaaact cggtactatt ttccatctgt ttgtgttcac ttcctctaaa ataagaataa
    12301 tttacttcta gtcagtcaaa gttaggtact taaatgtcgt cttcatgtct ccaaaagaat
    12361 ctttgttaaa gtcagcattt ttgtattgat caatcaattt ttgtgtatca ttgattgctt
    12421 taatttcggt ctccattcga ctgtctagtt gacgaatact ttcttgcgaa tctttatcgt
    12481 caggattttg ttgtaaacgt tccagatact cagcttttgt ggcttcaatt ttcttgatgt
    12541 tagtatttga agcatttaac tgatcttcta gcttatttac aacattattc ttacttgtaa
    12601 ctgctacaac ttttgaataa tcaatatcgc catctttggt aagaaagctt ccttgataga
    12661 cattagttga atctgaatat ggatttattc tgaaattgat attatcagga gtattaacag
    12721 gttttgcttt tttcccaaaa gaaattactc cttcattatt aacatcattc atagaatatt
    12781 gagaaagtgc ttttgtaact gaatctgctt cattcacatt gactttggta tcatcgtcag
    12841 ctgtatcatc accagaaatt agtgatactt ggtttgcaat aaaaacttga taagctcttt
    12901 cctctaattt accttttagg aataagaaag catccccatc agtacttaac atcccatagc
    12961 tcatttcaag cttcttagga cgatcttttt cttttgttgc catatataag ttatagtttt
    13021 ttccttgcgt agataacaac tttctagcgt tttgggagta accaagtttt actactgtta
    13081 catctctatt ttgatctgtc cacacatctg aaatagtgat ttctgctcct gatcgagcaa
    13141 actccaatga agaccctata ggtgttgtat tgttcacgag ataataatta tagtttccta
    13201 attgataaat gtagctaccc aagcctgtta ataaaaaaag cactcctaga aaagttgcaa
    13261 gcataatgcg taatccgtga cgtgttctct tatccttatc accaagcaac cctccaataa
    13321 tactgtattg atctttggta gatgttgaat tgacgttttt ttccatcagt ttgtctgccc
    13381 cctttcataa aagagcaaac aatcagacgt tttttcggta attctaggtt cgggattttg
    13441 aatcatttcg gtatattctt ccccattaat atttaacaca aaaattatct tcctttcttc
    13501 gttcctttct tttgctcttt attttccaaa taatcaatga tttttgctat tgtaccaaga
    13561 tagtaattcc cctcagcttt gttttttcgg attttgctaa ccattggagt aggtacaatc
    13621 tcttcatctc tcaattcact gaaagatttt ttacctagat attttccaat aacagatttt
    13681 aaaaaacgtt caaaatcttt ctcgtaagtt gttttcttgc cttttagttc atggttcata
    13741 ttgtcaacga cttttgcggt ttcaataatt gttttagttc tcagcttaat aatttcatct
    13801 ggaattttca atcctcgtaa tttcatcgtt gtactaactg gtaacccatg ctttactgca
    13861 tcagcaatac taaaactttt tagatcatct agtaagctct ccatatagtt aacaaattca
    13921 tgccaattaa tagcattcat tgtctcaccc cttcattttt ttaaaatgag gttcgggcgt
    13981 aacacattta tgttattata atatcataat aacataaata aatcaatcag caaatttaga
    14041 tatcccttaa agtatcagca attattcaac aagatattta ttttagctat ttcagtcatc
    14101 ataaaagact aattagcaat aaaataacta atattatcca tttatcagac gaaaagaaaa
    14161 aacttatcta attactctat attaactttt aacaaatagt tgacttgtcc aaaaatgtta
    14221 ccttcaatct cacaaagata ttaagatgtt tcctaccaaa actgatatca ccggactttt
    14281 tattctgtgt tgtccaaaag tgttaccttt agtcgatcaa caaattaaaa aaaattgttt
    14341 ttttcttgac ttgtccaaaa gtgttaccca tagttgttaa aatttgtata gattagccat
    14401 tctttcgaat attatttaga ctgaaacttg cttacaaaaa aacttcttgc atttattgtc
    14461 caaaagtgtt acccatactt ttttaaagaa gcaggttgta ttaaaattac aaccttcttc
    14521 ttctcaatct tcttctaacc aattatgcat tgaaatggtt ggcaagtttg attctggctc
    14581 actaaaagtg aatctgagcc gatcaactct tcttcctttc tttgcataga ttttttcata
    14641 atcaaaagtt tcaaatacct gtattccgtt ttcatcagga gctaaaaatt cttctttcgc
    14701 ctgctctagt attcttttgt caatatttgt cattctataa cttgaaggta tacttaatgc
    14761 tcttctaaaa tcttcaactt tgactaccca ataaccattt cgccactctt tatttctgta
    14821 ttgcatgaga tgacgataca attcttttgt gtagctactt cttagttttg taaaattatc
    14881 aagttcaaaa cgagtaaagt ttttgccaat tgagtttaag ataaattcaa attcctcatt
    14941 tgccttaatt gtaactgttt ccttctgttt atctatccgg aatttttgaa aaagccacag
    15001 ctgttcatag acgtctgaat cttcaaaacg gtaggttaaa gtacctagtt tgtcactcaa
    15061 agcttttaac acagaataaa aactgtcctt ttctcttctg tcgtatttga ccaaataacg
    15121 aaagaggttg aaatcaaaag ttacttctgc tgttccttga cgtttcattt ttgataaaat
    15181 agcccaaaac acatccattt caacaggctt aaatcctcgc aaagctgttg tattcagacc
    15241 attgttataa cgcacaattg catttgtttg ttctgatact aaatctacat cactatcaat
    15301 aatcttttcg gtaacttctt gagacattga ttactctcca atcttctttt tgcgctcctt
    15361 taatcatgtt aatctggtac taattaaagg aaacaatttt ttctgcttgt tacctaaatt
    15421 aaatcacaac taaaggtaac agtcaacaaa gatttgttac taatctaatt ttctattttt
    15481 tcgccttcca aatcaagaaa accgaaggta acgtcttatc ctagtgtgat acctcaaatg
    15541 tccacttttg ttacctttgc tgtccaaaag tgttaccctt actgtccact tttgttacct
    15601 ttactgtcca aaagtgttac ctttataccc ctttaatact tactctccca agagattaag
    15661 cctcccctaa cagatatatt aacagatatt taacagatat attaacagat atttaataaa
    15721 ggaggattac tcctctctta tttcaaaatc ttaaaaataa aaaatcttaa aaaaaactaa
    15781 cactatctag gagtttattt tgcttgtgta actttgaata attgaaaaaa aggaaaagga
    15841 ggaagcttca gcttcccctt ttatttatat ttataatata tattttaatc tttaaaactt
    15901 tagcaacctt caaaaaggct ttatatcaat cttaaataga ttttagggtg gacataaagc
    15961 gatgcgaaca tggacaaaaa gcgatgtgaa tgtggacaaa aagcgatgca aacgtggaca
    16021 aaaagcgatg tggtattccg aatatatcca aaaaaagaaa aagtatgtga atttatttct
    16081 aaaaactaga aaaatatttg ttttttaatt ttggtaattt ttataatttc gtattttttt
    16141 gaaaaggatt tttatattga aaatgttcta aaatagcgat ttctgctgtc ttatcaatga
    16201 aaattgatta aaaaaataaa atgtgtttta cagagattga gttatgttat aaatttacga
    16261 tacatttctt attgtatcgt atcgaaaaca ggtctatact tattcaatgg aatcgtacca
    16321 gttccaaatt tttaagctcg taccaagctt agaaagaaga ggcaatcgta tgaaaataac
    16381 agaaaagaat gtaaacccga aatttgaacc taccgaaagc aatctaaaaa agtttgattt
    16441 aactgttact ttatcgaatc aacttgtaga tagcattgtt gaaatggatg ctatgccaca
    16501 aaaaatttat ctttatgcta taggacatct tgaccctaaa aatccgcctt ttaataatac
    16561 tgttaaagta tctaaaaagg ctttatttgc gttgatgtct tctagttcat cttcttcaaa
    16621 acattcaaga ttaaaacaag ttattgaaaa attgcatcag caatctgtca ttaaaattca
    16681 aagaactaaa cctaacggta agactgaata caaagtcatc tcaccgctag aaattactga
    16741 attcaatgat ttttctgatg cagtatctat taaatttagt agttcaatta tgcctttatt
    16801 aacgaactta gaagatcatt ttacgcaata tacatttgat caagtagtta acttgacaag
    16861 caagtatgcg atcagttttt ttcaattatt cactaaagat tttaatctgt atgaagcaaa
    16921 tagagataac ttaacatgga gtacaaaatc acttgataga ttaaaaaatc ctgttttctc
    16981 cattgcagat ttacgaaaga aatttagtat tgagaaaaaa tataaagctt ttcgagactt
    17041 tgaaagacgt gtaattaaag aaccgattgc ccaactgaat aaatacactg attttaaaat
    17101 tgactatgag cttatcaaga agggtcatac ttatacaaac ataaagttct tgcttacacg
    17161 taccatgtca gttccggtac cttataagca agaacaaaga gaccctgctt atttaaaagg
    17221 cgcagaagat aaaacagaga aaatgaatca atcgtacttg aaagctatga atagcaaata
    17281 cactaaatta ctaatcaaaa actttttgat cagttctgcc gacttatgcg atcttaaact
    17341 tatgagccga cttcagaata aagtttatcc gctttatgat cgtttatcca aagatagagg
    17401 atttgaatca gttgtcaatc acctatctta cgttgctact cataaggagg attacacaat
    17461 aaaaaatact gttaaatatc tcgaaaaatc aattacgagt tatttgcctt atgtgaacct
    17521 ttatgattaa caactgaaaa aatgcgtgaa ggaaggaaaa acttttgaaa aaagatgaac
    17581 tgacaaagta caatgaggag ttcttagcaa caattgacat gaaaatggat ttaaagtcgt
    17641 atgaacttta tcaattgctg ttcagttata tctcacccac aaagctaaag aaaacaggcg
    17701 tagtagattt acctgttaaa gcgattatta attacatgga tgttgatcaa aatcttgaaa
    17761 cggaactaaa aaccatagtt aacactttgc aaagacaagc agtttatgaa atttcgaatc
    17821 tagacaaaaa atataagacg tatactactg tatctgctat tgatcggatt cattgggatt
    17881 tagaagagca tagtgtatct ttcagttttt cagaagatgt aattccctta attgtctcaa
    17941 tcaaaaagaa gtatccgttc tttgtttttg aagacttagc atcttttcaa aaaaaatata
    18001 gcatcgtgtt atacaaatat ttggcgatgt attataaaaa atatcttatc gccaaaaata
    18061 aaggagattt tgagaaagct gaaatatata agaatcccct gattgaaata gttaaaattc
    18121 gtgagattac gaaaacagaa aatgagtata aaacaatatc gaattttgat agacgtgttt
    18181 taagggaatc agttgaggaa attaatgaaa aatcaatgct gaatattgat tttgctaaag
    18241 ttagaaaagg cagaaattac aattttgctg tccagtttaa tatttctagt gagtttgatg
    18301 aaaaaactta tagagaaaaa aaattaggtt aatgcaaaat atatcttact cgtttgaaga
    18361 tgcttcagac gtatgctaag atatatagtg ccttgggagc aaggtattaa tctcctttag
    18421 aggttaatta gcttgtgatc gcctatcaat ttttttggta ggcgattctt ttttttgaaa
    18481 caaaaaagca aaaattattt tttaattaga gaggtgcaat gcgatgaaat actttttttg
    18541 tgcagtattc gaatggaaag gaaatgaata tgcagttaaa ttcccagatt ttccagactt
    18601 atatacacat ggtgaaactt tagaagatgc ttttgagatg gcgcaagaag tattggaagg
    18661 atacttggtg cttttagagt tgcaagaaaa agaaattcca tcgcctacgc ctgttcaaga
    18721 gttaaatgca agaatcaagc gatctgagaa tgttaattta tttgtcgtaa aagctaatac
    18781 gaaagttgct aaagctcgaa acaagcaaaa ttatgatcga aaatcagtga ctgtggaaca
    18841 ctatttaaat gttttagcgg ctgaagagaa tattaatctg tcgaaagctt tgaatgattt
    18901 gttgagagaa aagttgattt gatgtctctc agatgatcat attaagcaaa aacagcttgt
    18961 tttaggacg
//
LOCUS       DACGLI010000056        18813 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.058, whole genome shotgun sequence.
ACCESSION   DACGLI010000056 DACGLI010000000
VERSION     DACGLI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.058"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            38..1405
                     /gene="nhaC"
                     /locus_tag="IXT22_002232"
     CDS             38..1405
                     /gene="nhaC"
                     /locus_tag="IXT22_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4863568.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1686..2705)
                     /locus_tag="IXT22_002233"
     CDS             complement(1686..2705)
                     /locus_tag="IXT22_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863569.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2727..3734)
                     /locus_tag="IXT22_002234"
     CDS             complement(2727..3734)
                     /locus_tag="IXT22_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4863570.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3727..4392)
                     /gene="pgmB"
                     /locus_tag="IXT22_002235"
     CDS             complement(3727..4392)
                     /gene="pgmB"
                     /locus_tag="IXT22_002235"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4863571.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQTGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4385..6679)
                     /locus_tag="IXT22_002236"
     CDS             complement(4385..6679)
                     /locus_tag="IXT22_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4863572.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6939..9104
                     /locus_tag="IXT22_002237"
     CDS             6939..9104
                     /locus_tag="IXT22_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4863573.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9408..10241
                     /locus_tag="IXT22_002238"
     CDS             9408..10241
                     /locus_tag="IXT22_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAQ4863574.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10343..12043)
                     /locus_tag="IXT22_002239"
     CDS             complement(10343..12043)
                     /locus_tag="IXT22_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863575.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12550..13710
                     /locus_tag="IXT22_002240"
     CDS             12550..13710
                     /locus_tag="IXT22_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4863576.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13726..14169
                     /locus_tag="IXT22_002241"
     CDS             13726..14169
                     /locus_tag="IXT22_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863577.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14652..15182)
                     /locus_tag="IXT22_002242"
     CDS             complement(14652..15182)
                     /locus_tag="IXT22_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAQ4863578.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15287..15838
                     /locus_tag="IXT22_002243"
     CDS             15287..15838
                     /locus_tag="IXT22_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4863579.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15991..16464)
                     /locus_tag="IXT22_002244"
     CDS             complement(15991..16464)
                     /locus_tag="IXT22_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4863580.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16602..18074
                     /locus_tag="IXT22_002245"
     CDS             16602..18074
                     /locus_tag="IXT22_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4863581.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18071..18781
                     /locus_tag="IXT22_002246"
     CDS             18071..18781
                     /locus_tag="IXT22_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAQ4863582.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5765 a         3397 c         3890 g         5761 t
ORIGIN      
        1 atggcagggc cttttcattt gaaataggag atcgacgatg aataaaaata tttctttaaa
       61 agaaagtatc gctgtattga tcgtgttgtt ggcactccta ggagtactga tcatcggatt
      121 ccagctctcg ccacatatcc cgatccttgc agctttcatg tgtttgttgt tttatggcag
      181 atttaaaaag ttcacatggg atgagatcca tgacgggatc atcaaaggaa tcactccagg
      241 gatcattcca atcctgattt ttcttttgat tggtgtctta gttgcttcat ggattttatc
      301 tggaaccatc cctacgatta tggtttatgg atttaaactt gtttctgtgc gtttcttttt
      361 accgacagca tttcttgttt gtgcaattgt cggagtgact gtcggcagtt catttacaac
      421 gatttcgacg attggaattg cttttttggg gatcggtcat ttacttggat tcaatgatgc
      481 aatgactaca ggcgcagtcg tttccggtgc ctttttaggg aataactgct cgcctttatc
      541 agatacgacc aacttggcag cgggtattgg aggagttaat ctattcgaac atatcgctgg
      601 tatgcgttat acggatttcc cagcattcgt cctttcgttg attttttata cgatattagg
      661 acataacagt cattcagccg atctagctag tatcaatgaa atgatccaaa acatgaaagc
      721 gagcttttgg atctctcctt ggacattgat tccactagtt attttatttg ggggggcaat
      781 caaaaaaatt ccggctatcc ctacattact agcgggatcg acagctgctc tcgttctttc
      841 ttttatccat gagaaaagtt tgacggtcgg aaaagcagca gacatcttga tgaatggtta
      901 tgtcgcaaat acacctgatc caaagctaga tgaactgctt tctcgaggcg ggatcatgag
      961 tatgttaggt tctgctagtt tgattttact tgcattggca ttaggtgggt tactgatcaa
     1021 atatctgatc gttgatacca tcgttcaaga attaaaagaa aagatggacc gaccttctcg
     1081 tttagtcggg tttactgcct tgagctgtat cggaatcaat ctgatcgttg gagaacagta
     1141 tctgtccatc attcttccag gagaaacatt caagcgttct tttgatgacg ttggcttatc
     1201 aaaaacctat ttgacacgaa cactagcgga ttcaggtgcg accgtcaatt ctctcgtacc
     1261 gtggggagtc agcggcacat tcattatggg aacgatgaaa gttagcgcgt tgcattactt
     1321 gccattcgcc tttttctcga ttcttgcacc tgtctttaca atattaggcg gttttttatt
     1381 gaatcgtcga cgtgtaaaaa attgaaggaa ggaaaaaaga ggctgggaca gaagcgttta
     1441 actccaagaa ataagaagaa actcaagaaa attgcttttt aaatttttgt gaatttcagc
     1501 ttatttccga aggagttgct tctgcttccg ccgtttatac gtgtttagag cgtgagacaa
     1561 aagtgttctt tacttttgtc ccacgctctt ttttacagat aaacaatgtg ttagaagtag
     1621 tatcttcttt tacataaaaa gctgaccata ggataaatgg tcagcgtatt tagtgagtca
     1681 gctatttagt atgggttttc taaaggaacg actgtctctc ttttgatcaa gcgatgaggg
     1741 atgaccaaac gtacgccact gctcaattct tcatggatca attcgcgcag cttttgcata
     1801 gcgacacgtc ctaattcgga gatatcgata tcgatacttg taaggtaagg gtgtgttaat
     1861 gttgagaaga tcgagttgtt gaagctaatg acggagagtg tctctggaat gacatagcca
     1921 tacatttgcg ccaactgcat cgtgcgaagg gcgaagatat cgtcaatgac caccaatgct
     1981 gtggcttcgt tttctttcaa cgttttctca aaggacagat aatcctccgg atgctctagt
     2041 actacactgg ataacgcagg aagaccagcc atcatcattg ctttttgata accgaaatat
     2101 cgttcgaaat acaaactttc atgagtcgtg tttgtcacaa acaggatatt cttatgtcca
     2161 ttctggatca aaaattctgt tgcttgttta cctagaagct ggttatcatt atctacataa
     2221 acgatttcgt tctcatgatg ataaggctgt ccgatcaaag tgaaagggat gtggttttgg
     2281 tataaataat caatgacagt atcttgacta tctgaataca ctagaataaa accatctact
     2341 tgtttttgta aatgcatacg ctggacgttc tctaacagca attcaaaatt tttagcagta
     2401 gcgattgctg tagtcatatc ataattccgc gcttcttcgt tgattgcttc catgatctca
     2461 agataaaatg ggttaccgat ccgctctttt gaatcaagag ggggtaagat tacgccgatg
     2521 gcactggaaa tgcgttttcc tagattgcgg gcagtcatgt taggaacata acctagttca
     2581 tccataattt ttcggacttt cttctttgtt gtctcggaaa tactaggatg atcgttgatg
     2641 acacgagaga cggtcgaggt ggcaacaccg gcttttttcg ccacatcttt tacggtaata
     2701 gccatgataa aaacaccttt ctcttgttat tgtgcagaga accgataaat cgtctgactg
     2761 atccgttctt gaccaggatg gaggttgatc gatccaaatt tggggaaatg aacgatatca
     2821 gggatttctt gcggttcgat tgctaatccg tagtttgaat gcatctgttt tccattgaca
     2881 gagaaatcag cttcgaatcc agtcgtagaa aataatacca tacttttatt agaagttgct
     2941 atagtcattt ggcgaccaga atgcttctcg aataattgta aggaagtttt ggaaagccta
     3001 ggatgatgca aaagaaatac atcatctagt ccatctggat aacatgcaag gatctcttgc
     3061 agtgttgggg attttctaaa gtcgattggc agtttttctt tttttgtcca atttccagta
     3121 ggcagttttt cttgatctaa ttcaagcaca ccatctaaaa agaccgttaa ctgatgttca
     3181 tagatgtctc ttgttccatt tcctgaaagg ttgaagtagg catggttggt cggattgcag
     3241 atggtttcaa caaggctact agcagaggtt gtcatctcta attcgttttt tgttaaacgg
     3301 taagtgatcg tagcagtgat tggtcctgga taggtagaaa attcatcttt taagtaaaag
     3361 accacaccta ttgatgatgg agttttgaaa acttctactt cccaaaattg gaaagaccag
     3421 cctttcgtgc caccgtggat atggtgtgat ccgcagtttt tctccaatct atgctcaccc
     3481 caagaagcat cccggatcct tccggctaca ggtccgacag ttgctccaaa aaagcttttg
     3541 tctgttagaa catcttcgaa acgatcgtaa gacaataaaa cattttctga ttttccttct
     3601 ttgtctggtg cgaagatttg gtgcaggcgg gcaccgtaat tgagaagaac gacttctaag
     3661 tagtcgttct tcaatgtgat tttctttatt tcagtctctg gaactggtac gacggagatc
     3721 tctggattat ccatggtcat gccacttttc tttcaagtaa tcgatcgtaa gaaaagtcgt
     3781 atcagggaca agcgggatct cctctccaag gtcttcagca cgtcccacgc caattggttg
     3841 agcgccactt gagaggatgg cttggatacc ggtttgcgcg tcttcgatcc cgatacattc
     3901 ttctgctttt agtccgacag cttttgctgc aaggaggaag atatctggcg caggttttcc
     3961 gtttgttgct tctgccgggt cggcaatagc atcaaagtaa ggtgtaagac ccattttttc
     4021 aagtaggaat ggcccgtttt tacttgcaga agcaagagca atcttgattt tttcttcttt
     4081 taaagaatcc agtaaaggca cgaccccggg gaagacatct tttggttcga tcgtctggat
     4141 catctctaaa taataatcgt tttttctttt cgctaattct gcaaattctt cctttgaaaa
     4201 agagtgttct tttccgccat aagctaaaag caaagagagt gagtcttctc ggctgacgcc
     4261 ttttagctgt tcgttgaatg tgtggtcgat cgtaatgccg atttcctgac caagctttcg
     4321 ccaagcacga taatggaatt cagcagtatc ggtaatgaca ccgtctaaat caaacaatac
     4381 ccctttaaac atttgcttcc tcctttctta gcgttatttc tagacgatcc gctaaagaat
     4441 aagactgttc atagacgtaa atttctagag gagaaccttc taataactcg aaagtaactt
     4501 gttcatctgt gactgagatg aacaataaac gtccgcgata attgatatgg aaagaataag
     4561 ctttccaagt ttttggcaga aatggtgcga atctcaactg atcatgggca gttttcattt
     4621 gagcaaatcc ttggacaatc gacaaccagc taccagtcat ggaagtgatg tgcaagccgt
     4681 cttctgtgtc gttattgtaa ttatccaaat ccaagcgagc tgttcgctgg tacatttcta
     4741 cagctttgct ttccattcct aattctgctg ctaaaatcga atggatactt ggcgaaaggg
     4801 aagactcatg gacagtcatt ggttcataga aatcaaagtt tttttgcttt tcttcttttg
     4861 taaaagtatc attgaagaaa taaatcccct gtagtacatc tgcctgcttg atgaagcaag
     4921 atctaaggat tttgtcccaa gaccaatgct gattcagagg aagatcgctt gtgggaatat
     4981 cggatacagg catgagatct ttatctaaga atgtgtcatg ctggacaaag attcctaatt
     5041 cttcgtcaac tgggaagtac atgttctctg cgatatcttt ccatttggct agttcttctt
     5101 cgctgatagt gatagcagct tctttttgat aagttaaata attttctcgc gtgtaacgca
     5161 agacccaagc tgcgatcgta tttgtatacc aattgttatt gatattgttc tcatattcgt
     5221 ttgggccggt cacaccgtgg atcatgtatt tatttgctcg ttttgaaaaa tggacacggt
     5281 ctgcccagaa gcgtgcgatt tctgctaaaa cttccagtcc ttcatttttc aaatattccg
     5341 tatcgccggt gtaattcgta taattgtaga ttgcataggc aatcgcgcca tttcggtgaa
     5401 tctcctcgaa tgtgatttcc cactcgttat ggcattcgac accagtgaag gtgaccatag
     5461 gataaagcgc gccttttaat ccttgttgct gagcgttgtg gattgcttgc ggcagttgat
     5521 tatgccgata tttcagcaga ttcttagtta cttcaggttt ggctaaagca agataaagag
     5581 ggacagcata cgcttctgta tcccagtaag tggctccgcc gtatttttct cctgtgaatc
     5641 ctttggggcc gatattcaat cgttcatctt cgccgtagta agtagagaat agttggaaca
     5701 aattgaatcg aataccttgt tgtgcttctt cgtctccttc gatgaccaca tcggcaagct
     5761 tccatcgttc tgcccaagcc gctgtttgct cttcttttgc ttggatataa ttgtttgtct
     5821 ggttcgttaa ttctgagaca gctttttctg cttgctgcgc ttctggaata tctctactag
     5881 taagaacgat aatttctttt tccactgacc atgtctcacc ttgagataat tctgcagaca
     5941 agcaaccatg taatgctaaa gtatcttcgt gatagtcagg gatgactgat tttccattaa
     6001 cgaaatggcg cattgctgca gtaacagtaa attgttcaat cccaaagttg tttggaatag
     6061 ttttagtcgt caaatagccg atttcttcta tagttccacg atcaatctca ttccaaaaat
     6121 gttcatcata gttgctgtct tcgttttgaa catttccatc caattttgat acgagtttga
     6181 ctgttccgct accttcaagc atttctatag ttaaatagat ataagctgat tcttttttga
     6241 caatgctcag aaaacgttcg aaggaaatgc gtactttatt agtagaagta gtgattgtga
     6301 atgtacgaga taatacacca tttttcatat ctaattccca gtaaaagtct tctggttcca
     6361 aagaagccaa gtcgatcagc tgatcgttga tcgaaatatc tatcgcgata aagttcaagg
     6421 cgttgatcac ttttccaaag tattctggat aaccattttt ccaccagccg acacgtgtct
     6481 tatcgggata ccagacaccc gccaaataag taccttgatg gtggtcccct gagtaagttt
     6541 cttcaaagtt cccgcgcatc cccatataac cgtttccaat acttgttaaa gattcttgca
     6601 gtcgaagatt ttttttatct aattgtgtcg tgctgatttt ccatggatca atagcaaata
     6661 gtcgtttgat ctgtttcatt tttctcctcc taatgagctg ttttatacgt tcataataaa
     6721 cgcaaccgat tgcacaagtc aatagacaaa agaaaatatt tcatagaaaa aagcttaaaa
     6781 aaataaattt ttaggagaaa attatagaag ggaacacacg tattataggt tttatagaat
     6841 ggtatagaca gaaaaataaa aaataaagca tttacaaaaa agaaaacgca cgctataata
     6901 cgtttaacga aaccgattgc gtaaaggagc taaacggaat gaaaaagata tttagttttg
     6961 agttttggca aaaatttgga aaggctttaa tggttgtggt agcagttatg ccggcagctg
     7021 ggttgatgat cagtataggg aaatcaattc ccttgatcaa tcctgattgg acgccgcttg
     7081 tcacaacggg cggagtaatt gaaaatattg gttgggcaat tattggtaat cttcatattt
     7141 tatttgcttt agcaatagga ggaagttggg caaaagaaag agcaggcgga gcatttgcag
     7201 ctgggatctc atttatttta atcaatcgga tcactggggc tatctttggt gtcacaagtg
     7261 acatgcttgc gaatgaagat gcatttaccc acactctgtt cggtacgaag atcatggtta
     7321 aaggattttt tacaagtgta ttggaagcac cagctttgaa tatgggagta ttcgtaggga
     7381 tcatcgctgg atttgtcggg gcaatggctt ataataagta ctataattat agaaaattgc
     7441 cggatgcttt gtcatttttc aatggaaagc gctttgttcc gtttgttgtt atcttatggt
     7501 caacaatcgt ggcattgatt cttgctgtgg tgtggccaaa cgtacaggct ggaatcaata
     7561 attttggttt atggattgca gaatcacaag aaagcgcacc gattctagca ccgtttttat
     7621 ttggaacatt agaacgttta ctattgccat ttggattgca tcatatgctg acgattccta
     7681 tcaactatac acagcttggc ggatcgtatg agattttatc aggcgcacag gcggggacac
     7741 aagtatttgg gcaagatccg ttatggttgg cttgggccac tgatttagtg aatcttaaag
     7801 gtgcagggga tatgtcgcaa tatgagtttg tgttgcataa ctggacgccg gctcgtttca
     7861 aagtaggaca aatgattggt tcttcaggta tcttgatggg aatggctttt gcgatgtatc
     7921 gtaatgtcga tcctgataag aaagcaagat ataaatcaat gtatttttca gcagcgttgg
     7981 ctgtctttct aacaggtgta acagaaccat tggagttcat gtttatgttt gctgctgtgc
     8041 cattatatgt catttattca gtgatccaag gggctgcatt tgcgatggca gatatcttgc
     8101 cattgcgggt ccattcattt gggaatatcg aattgctgac tcggacaccg ttagctatca
     8161 aagcgggtct aggtggagat cttatcaact tcgtgttgtg tgtgatcgct tttggtgttg
     8221 ttacgtattt cttagcaaat ttcttgatca aaaaattcaa ctttgctaca ccgggacgta
     8281 acggaaatta cgacaatgac agtgaagaaa ccgttgtatc taacagcgga acaggaacag
     8341 cagatcagca agtggtccag atcattcatt tgctgggagg aaaagaaaat atcaaagatg
     8401 tcgatgcttg tatgactcgg ttacgcgtaa gtgtaaatga tcgagaaaaa gtagggactg
     8461 aagaagcctg gaaacgagca ggggcgatgg gattgatcgt caaagacaat ggagtccaag
     8521 cagtttatgg accaaaagca gatgtcttga aatcagatat cgaagatctg ctgcaatcag
     8581 gagcagagat tccagagcca gaaatggttt ctacaggaaa tggacaagca ggtagtaagc
     8641 aatacttagg tatagaacaa gaactagttt ccgcagcttc tggagaagtg attcctttat
     8701 ctgaagtaaa agatccggta ttctcacaaa aaatgatggg tgacggcttt gctgttattc
     8761 caacatcaag agaagttgtt gcgccgatcg ctggaaaagt gacaagtatt ttccctagca
     8821 aacatgcaat tgggctggaa acgaaagatg gtatcgaagt tttgatccat atgggaatcg
     8881 atacagtcca aatgaatcag ccagcttttg agattgctgt caaagaaggc caagaagtag
     8941 gaacaggaac gaaattagct gagatggatc ttgatgtgat ccaaaacgaa gaaaaagatc
     9001 caacgatcat gatcgtattt acaaacgata aagtagaaga agtagtgatc aagcaattag
     9061 gtacagtgac agctggtaaa gtgatcggct ccattaaaat gtaaggagag gttgtgaaaa
     9121 agctgtcctg catcaagtca taagaacagc caaacaaaaa tagctcctcc tatttttcgt
     9181 ttggttgggc ttattaccga gaagcagcag tttgaatact gtttagtgga gaggtcgtga
     9241 aaaagctgcc ctgcaccaag tgataaaaac agccaaacaa aaaatagctc ctggtccatt
     9301 gagcttatta ctgaggagtt agcaggagaa cactatttgc tggagaggtt gtgacaaaaa
     9361 ttttgtcaca acccttttgt ttcgaaatga agacaaggag aaaaccaatg aaattcatga
     9421 cactcaacac gcatagctgg cttgagccag aaccagagaa aaaattgcaa gaattagcag
     9481 ataagatcct gttagaagat tatgaagtga ttgctttaca agaaatcaac caattactgg
     9541 aatctgaaga agtagaacct gcgaagctaa tgaagttctg tccggtaaag aatcaagtac
     9601 ctatccgtaa agataatttt gcctaccgtt tagttcagct tttaaaggaa cacggaaaag
     9661 agtatttttg gagttgggaa atgagccaca tcggttatga taaatatgaa gaaggaaatg
     9721 cactgcttac gaaaaaaaca ttggaaagtc aggtccttac cgtctcccaa tttcaaaaga
     9781 aagaagatta tcagacacgc aagatcttga ttgggaaaac aaagatagat gatcaggaca
     9841 tttttgtctc gagctgccac ttttcttggt ggacagataa aaaaagtggc ttttattttg
     9901 agtggaaaaa cttggaaaac tactttttgg aaactcgcgt accacttttt ttcctaggtg
     9961 atttcaataa tccagtagac tctcaaggtt attatactgt aagagaaagt tgccttcttc
    10021 ttcaagattc gtatgttgtc gcgaatgaaa aaggaaaagc agctactgtg gaaaagaaaa
    10081 tagatggttg ggaacaaaat acagaaaaat tgcgtataga ttttattttc gtccctgaag
    10141 gaatgcaggt taaaaaatat caacggattt ttgatgggat cgatagtcca atcatcagtg
    10201 atcactacgg ggtggaaatc gaattagatg tgaacgaata aaaaatataa catataacat
    10261 aaaaaaactg attaaaataa aactctccaa acgattatac cgtttggaga gttttttgat
    10321 cggatgtatt tatccctttt gcctaagcac gtaaaagctt gtatctatga taaataaata
    10381 aacatagcaa ggtaaaccag ccaatcaaag taagagaaag aatgaaatag aaatagattg
    10441 gcgtttgata atgaagcgtg agctcgttga ttcctttttg ctgcttcacg attggggtcc
    10501 cgatatctgt tacttcataa tcagtcaatg tttttccatt ttgctgtagc acagtccgat
    10561 cgtagacgat aacagggata tgaacagttt tgtccccagt gtttttccac ttgattgtca
    10621 aaagaccgcc tggatgtgtt tttataaaag ttgtttcgtt ttctagtatt tcttcgttat
    10681 accggtcgta tttattgtct tttgtctcct tatagattgg cagatagtca ggtgtggttt
    10741 tttggaaaac gaacaagctg gtagacatat ctttgctgaa gaatgttttc cttgcttctt
    10801 ccggcgtatc gaatagataa gtatgtcgac tgacaaatgt ttcattttcc cacttttcca
    10861 gatgctggta taagttctgg atcgtctgtg ctgaaaaaat aagaatgcca aatatactta
    10921 aaagacggaa ccacttttgt tcagaccact ggttcagtga aagggcaagg taaagtagaa
    10981 gcaatagcgt aaatggcacg aaaaatcgaa atggaaactg gatcaaacta ataaaaggca
    11041 catttttttc gatcaatgtc gtccatggaa tcaagctagt agaaagaaaa aagaaaacaa
    11101 gacttgtgta caacacgatt ttttggaata aggtgttctt ttgttgaaag aaaataaaaa
    11161 gcaaaaaacc tgataatatc aatataggaa aggccttagg gtaatggagc caataactgc
    11221 catccagatc tatcgccttt tgactcattt ctctgttaac aaagggagga agaatcttat
    11281 tcccactgta aacaatagct aatcctgccc aaatatttgc tgtcagaaca aaataaagca
    11341 agaccgactt aatcagttga agcagtgctt ttcctttttc agtctggtta aaaaagtaat
    11401 aaagataaaa agggatatac atcaaagcta acatgatcga agacagtaaa tggatctgtg
    11461 tcataagtcc cactgagaca gcgactttga taacagggaa ctttttatga aggacgaaat
    11521 cagcaatagg gatcatacat aaaggataaa aacaagtccc ccagctagtg aatccttggt
    11581 tgatagacca gtattgaata gaatacgtac tcatgaataa aacggctact ggtacactta
    11641 cccaatttcg aacattgaca tatctcagta aaatcagcat agaaaatcct gaaataagat
    11701 aaagaatgaa atttgaaaga atctgataat gaaaccagct acctgcaagc aacacgatca
    11761 atccttgtaa ataagcgaaa aatgggccgt aaacggcatt cacgatcctg ccactttgct
    11821 ggaatccata aagggaagga aaataatgga aatccccata tttaatttgt tgcgcggcat
    11881 catagaaccg attgtaatgg aatggggcat cagcacccaa aattagttta tgtgtgaata
    11941 aatgaggcat gagaaatgcc aaagcaatga aaaaaattgc taaaaatggg ccatattttt
    12001 tcaattgtcg aactcctttg caaactttag ataaattcat catatatcct atgcgagagg
    12061 taggcaagaa attagaaaat tcatgaaaat atttatgaat tttacaagaa aaacataagt
    12121 gaaagttcta aggagagagg atgcgacata agttttgttg catctccttg ttttgaaaca
    12181 gaatttttct taatactcga aacaaagtag ctttttcatg acctctcggt aaacggtgtt
    12241 caatcagctg cttctcggta ataagctcac tagcctagaa aatatgagaa gctattttct
    12301 gactagcgct cttattactc aaagcataac gcagttttca caacctcttc cttaaacggt
    12361 gttcaaaagc ttgcatctgc ggtaataagc ccaacccaac aaaaaatatg agtagctatt
    12421 tttttgggct gtacttatta cttgatgcag gacagctttt tcacaacctc atcggctttc
    12481 attttctatt tttttcctga acccatataa taaaagaaag aacaaaaaaa cttgcaaggg
    12541 aggacacatg tgaagcagag taagcaaaaa cagtctcgtc gacttttgtt tcgtttgttt
    12601 ttattaatat gtatcgtcgt agggttactg atcgctttat atccatttta tgtggattct
    12661 ttaaatagtt ttattgatca aaaacgtatc gaacaagtac aaaaacggac cgcagctgaa
    12721 attgaagtgc agcgaaagaa aatggaggag aaaaaccaac gattaactga ccaaggattc
    12781 aatcctggta ctgatccttt caatgaaaag aacagaaatg aaagtacaac atccagccaa
    12841 ttagaggaat ggctgatcgg aagtatcaat atacctaaga tccaattaaa tatttcactt
    12901 tatgatcggc tcaatggtag gatccttgaa aatggagcag gcgtcttgca aggaacctct
    12961 ttcccgcttg gtggaaattc gacgcattca gtgatctctg ctcacagcgg tttacctaat
    13021 cgacggttat ttaccgaatt agatcgttta gaaaacggag acacgtttat tttgactgtt
    13081 ttgggggaga aattggctta tcaagttaaa aatatacaag tggtactgcc agatgacacg
    13141 tctgttctaa cgatttcaga aggagaagac ttagttacct tgcttacatg tacgccgtat
    13201 atgatcaaca cgcatcgttt gctagtgaca ggacatcgga ttccttataa cgaatcggta
    13261 aaaaaagaag aaggaaaagg aaatcaggaa agaaccatgc ggcaatggtt tattcttgca
    13321 ggaacgataa tagctgtagt catactgtta gtgtttatcg gacgactaat ctatcagtat
    13381 agattaagta aaaaagtgct tgatttttca tttattatta gtgattcgtc agggaaaccg
    13441 gtaaatggta gttcattcat tttgaaacat aagaaaaaaa cacttactag aaatggtgtg
    13501 ccgttttcag tacaaagcga ccatcatggg aaagtcaagc tggatcaatt gcctggtgga
    13561 acttatcgaa tcgtttcagc tgatgatcct aaagttgctg tttcttttgg tattagaaaa
    13621 gtaaaacaag agaagatata cttttttgag gggcgaaaac ttgtaaaaga gcttcaaaaa
    13681 aatggttttt attttaaaat caatgaataa gtaaggagag aaaaaatgat ccgcacaaca
    13741 acaaaattgt ctgccaaaga actggaatct gttctatcga tttggctgca tgctaacttg
    13801 gattctcatg aattcattcc atcaacttat tgggagaatc aagtagaatc tgttaggaaa
    13861 gctttaccag atgcagtgat ttacttagca gaaatagatc aagaaattat tggttttgct
    13921 ggggtgattg atcagtttat cgcaggaatc tttgtgaaaa gggaataccg gcaacaaaga
    13981 atcggtacgc aactaatgaa aaaaataaaa gaaaccaata aaacactgac tttgacagtc
    14041 tatcaaaaaa atcaatcagc tattcatttc tatctttcac aaggttttac aattcaaaca
    14101 cagcaaaaag atgaagcagt aaatgaggag gaacttgtga tgaaatggaa tcaaaacgct
    14161 gatttttgat gaacagaata acgaaataat gctcccagcc taattttttg ctgggagcat
    14221 tatttcattt tgaagtcact aatttaactg tgtgaatatg cagttgttac aatctttgat
    14281 aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa atatgaggaa
    14341 ctatttttcc atttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttga
    14401 taaacggtgt tcaaacggct gcttctcggt aataagccca ctagcctaga aaatatgaaa
    14461 agctattttc taactagcgt tcttattact caaagcataa cgctgatttc acaacctctt
    14521 gataaacggt gttcaatcag ctgaccctcg gtattagctc aaaaaacggc aaaacatgag
    14581 gaactatttt tccgtttctt tctctaatac tcaggtcaga acgctgattt cacaacctct
    14641 ctttcacaac cttattttac tcgtttataa ttttcatcga agtattttcc gctacggata
    14701 tcatctggca ttccatcgta tggttcttcg ctaataacat cttcattgtc tatacctgca
    14761 tcacccatat aagtgatcgt agcaaattca ggaacaagta attttggata agtttcatat
    14821 ttttcacgag ctgcttccat ttctgcgata tgttcgtttt ggaaagtaac agtgatttct
    14881 ggatgttctt caacccattt agggaaaaag atcattccgt gaagtttctt ttcatttggc
    14941 ataaagtcca atgccacgtc tgtccctgtt ggctctgtcc aagtgatttt gaatacgccg
    15001 tccgtcaatt taacgatatc agcttcttgg tcttttaccc aacggccttt gaccattccg
    15061 ccatggatac ggtaatcaac agtatggtca tttttggcat accattcata ttcccaacca
    15121 ttgtcatacg tatagataaa gtgagttcca ataaaatctt ccaattcttt aaattctttc
    15181 atgtttaagc atctccttat aaattaaaac atgtaataaa ctacatgttt tcgattactc
    15241 atttatgata gaatggattt aaagatttgt caaggaggga aaactgatgg caagaaaaaa
    15301 tacacttcga tatattttgt tagggttatt aagtaagaag aagatgacag gatatgaatt
    15361 gaatcaatcg ttcaaaaatg aaataggaga attttggcaa gcaaaacata gtcagattta
    15421 tcctgaactt gcaaaaatgg aagagcaagg aatcattcag catcaagtag agatcacagg
    15481 tgaaaaattg gaaaagaaag tttatgaatt aacagaagaa gggaaggaac aattggcaga
    15541 gtggattcat acacccacca atgaactacc ggttaatcga gacgaatttg ttctgaaatt
    15601 gtatttcgtc aaagacgtga atgatccggc attagtagaa attattcagc agcagcgtga
    15661 ccttcatgaa gaaaaacgac ttcatctatt agagcgaaaa aaaacgatct ttcctactga
    15721 aaaagaaaaa catgaaaatt acggacacta cctgatttta gcgcatgcga tcaatcggga
    15781 aacagaatat gcaaattggc taacagatgt attagaagaa agtaaccgaa aaaaataaaa
    15841 aaatatccga acagtgatgg agaattcctt tctatatgaa agaaacgcag atcaccgttc
    15901 ggatattctt atgttcaaac aggccttttt tcaagtattt atgtagcatc tacttattaa
    15961 aaagcttggt acttaggaga ttagtggcgt ttagagttct tttaacaact gttcgtagtc
    16021 agctttttca tcgacaggaa ggagcttgta agttaattcg tctgtctcgt tgtcatgaat
    16081 gatgtacatc ttagcattct cttctttgaa gttaccgatt tgtaaaatcg tatagcgttc
    16141 gtcgatcaat tcgatatctt tgattgcttt tgaaaaaact ttacggacat ggtgcatttt
    16201 cttttggcgg atttctgcct tttctgcagc ttttgacaaa gtaaatccgt catctaaata
    16261 ttttttgatc agttctactt ttatgactgt aggtaaacga tattttctag gacaattcgc
    16321 atcagcttcg atcgaacgaa tgaatccctt ttgttcccaa taccttaatt gacgtggaga
    16381 cacacctacg atatcactta attcactgat gccaacaacc aattgatcat tttccaacaa
    16441 acgtttaagg gaagccccaa ccatttttgt cactcctttt gtcctcttgc ttcccttaat
    16501 tatatccgta ttaacttatg tgtcaagtag gttgacaaat agcgaattta ggactaaagt
    16561 attctagtag tttcagaaaa aattcagaaa gaaggagaaa tatgagtaac aaccaacccg
    16621 tagatattta cggaaaacca tataatcgga cacttttagt tgttgtctta ttaattggta
    16681 cattttgtac cgttttgaat cagaccttat tgacgacagc ttttcctaca ttgatgaaag
    16741 ctttcgatat ttcagcgtct gatgtgcaat ggttaacgac tggtttcttg ctagtcaacg
    16801 ggatcatgat cccaataaca gcatggctga tcaataaatt cagttcaaga aatttatatc
    16861 tttctgccat gacgatcttt ttgatcggaa cgattacttg ctttacagca cctaatttta
    16921 gtacattact aatcggtcgt ttgatccaag cttgcggtgt gggagtatcg atgccattat
    16981 tgcaaaatat catgctatct attttcccgc cagaaaaaag aggatcagca atggggatgt
    17041 cagggatcgt tattggactt gctcctgctt taggccctac attatctggt tatatcattg
    17101 ataactacca ttggcgtgac ttgtttggta tggtactgcc aatcgttgtt cttgtcttgg
    17161 ttttagcatt cttcctaatg aaaagtgtta ttccattgtc aaatcctagc attgatattt
    17221 tatccgctat tttatcaacg attggattcg gtagtttact ttacggattt tctagtgtag
    17281 gagatgacgg ctggggaagc ttgaaagtaa ttggtttctt agttgttggt gtgattttca
    17341 tcgccttgtt ctcatggcgt caattacatt tggaacatcc attcttggaa cttcgtgtat
    17401 tcaaatcatc tacattcacg attgcagctg ttttagctgg tgtaacaaat atggcgatgg
    17461 taggggcaga aatggtcgta ccattgtata ttcaaaatat tcgtggagaa tcagcattcc
    17521 attctggctt gatgttgttg ccgggtgcat tgatcatggg ggctatgatg cctgtgacgg
    17581 gtgcgatttt cgataaatac ggcgcgaaac gtttagccat cacagggatg ttcattttga
    17641 cagcggcaac tgcaccattt gctttcttga caaaaacgac tccagtttta tatatcgtga
    17701 tcctttatgc gatccgtatg tttgggatct ccatggtcat gatgccggta acgacttctg
    17761 gtatgaatgc attgccaaat aacttgatca gtcatgggac agcggtaaat aatacattcc
    17821 gtcaaatcgc aagctcgatt ggtacagcta ttttgatcag tgtgttgacg aatgtgacaa
    17881 aagcaaatat cccaagcaaa tctgtattgg ataatacgcc attagcttat aaagatcagg
    17941 caatcaatgc cacactgtca ggttaccatg ccgcgtttat cgtagcgatc atctttggga
    18001 ttcttggctt tattattgcc tttttattga agaaaaaaga acctgttcta atgaaagcgg
    18061 gggataatgc atgattattg gagttttgat tgtcagcttg cttgcttttg ctttaacgaa
    18121 cgtgttcgct aaaaaaacat ggcaaacctt tttatctttg attttcggac taatcttcgt
    18181 cgcttcacta agtttgatcg tcgctaattt gtccaatcac tttggaatgg aaaaagtaac
    18241 ggaaacaaaa acagaaaaaa ttgtttccag tgctgattcc caaggagcag atatgctttt
    18301 gtataaagct ttagggaatg gaaaagaaaa agtgtatctt taccgaacaa atgaaaaaca
    18361 agaaaaacca aaagcaactg gtacggataa cgaaacaaat aaagtagaaa agacagacgg
    18421 cgatgctgaa aaagtgacga aaactactta ttgggaatac aaaaacgaca tgtataaatt
    18481 ctggttcaat attgctgata acaatcacga atatgacagc cgagtgaata cattcaaaat
    18541 cccagagaca tgggtagaat taagtacgga ccaagcagcc aagttagctg aattagtgaa
    18601 gaaacagcaa agtacgatgg aaagtgaagc aaaagcttat gttcaagacg gtatggtaaa
    18661 agcaatgact gaaaatccaa aaatgagcaa agcagagcaa gaacaacgta cgaaagcctt
    18721 agctgctgaa ttccaacaac aagcattcgc aaaattagtg aaagaagcaa aaggcgaata
    18781 atattttgaa caccatgtag gaggttgtga aaa
//
LOCUS       DACGLI010000057        18123 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.059, whole genome shotgun sequence.
ACCESSION   DACGLI010000057 DACGLI010000000
VERSION     DACGLI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.059"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(24..722)
                     /locus_tag="IXT22_002247"
     CDS             complement(24..722)
                     /locus_tag="IXT22_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAQ4863583.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="IXT22_002248"
     CDS             complement(715..2067)
                     /locus_tag="IXT22_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAQ4863584.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="IXT22_002249"
     CDS             complement(2290..3690)
                     /locus_tag="IXT22_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAQ4863585.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="IXT22_002250"
     CDS             3851..4588
                     /locus_tag="IXT22_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAQ4863586.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="IXT22_002251"
     CDS             4713..5192
                     /locus_tag="IXT22_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAQ4863587.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="IXT22_002252"
     CDS             5189..5956
                     /locus_tag="IXT22_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863588.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="IXT22_002253"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="IXT22_002253"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4863589.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="IXT22_002254"
     CDS             complement(6859..7461)
                     /locus_tag="IXT22_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4863590.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="IXT22_002255"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="IXT22_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="IXT22_002256"
     CDS             8142..8726
                     /locus_tag="IXT22_002256"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4863591.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="IXT22_002257"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="IXT22_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAQ4863592.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="IXT22_002258"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="IXT22_002258"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAQ4863593.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="IXT22_002259"
     CDS             10627..10806
                     /locus_tag="IXT22_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863594.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="IXT22_002260"
     CDS             10828..11853
                     /locus_tag="IXT22_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAQ4863595.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /locus_tag="IXT22_002261"
     CDS             12028..13272
                     /locus_tag="IXT22_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAQ4863596.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="IXT22_002262"
     CDS             13425..14372
                     /locus_tag="IXT22_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863597.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="IXT22_002263"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="IXT22_002263"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAQ4863598.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="IXT22_002264"
     CDS             complement(15274..15516)
                     /locus_tag="IXT22_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863599.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="IXT22_002265"
     tRNA            15637..15709
                     /locus_tag="IXT22_002265"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
     gene            complement(15828..16466)
                     /locus_tag="IXT22_002266"
     CDS             complement(15828..16466)
                     /locus_tag="IXT22_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4863600.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16589..17221)
                     /locus_tag="IXT22_002267"
     CDS             complement(16589..17221)
                     /locus_tag="IXT22_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4863601.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17572..17871
                     /locus_tag="IXT22_002268"
     CDS             17572..17871
                     /locus_tag="IXT22_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4863602.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6214 a         3162 c         3570 g         5177 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat
    15781 aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa
    15841 acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc
    15901 gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg
    15961 atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca
    16021 aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg
    16081 agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat
    16141 aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc
    16201 aaaaataccg agactgcggc actgattact acattgataa aaaaatattt ggctatattt
    16261 ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt
    16321 gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat
    16381 agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct
    16441 attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata
    16501 gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct
    16561 aaaaatttat cttatatatt cattttgatt atactacttt tatttgtaaa aattttctag
    16621 caaaaccaag tgcttgcaac tgattaagcg tacaattttt tagatgttcc gagcgtactt
    16681 caatcatttc aaaggagttg ctacttaaat cgatattttt taaatcagta tcaaaaaagc
    16741 tagcattttc taaatcatta gtagaaaaca ttattttagt gagggaacag tctacaaaat
    16801 ctgcgcttga taagacagag tgctcaaagg tactttcttt tatgtttgaa ccagataaat
    16861 ttacatagtc cattttacaa ttctcgaata acgtgttccc aatataactt tccatcaatt
    16921 tagtacctgt taatttacaa ttgacaaatt tcacgcgatg caacatgctt tttgtcaata
    16981 tacagcctga aaaatcacag ttttcgaata tacagtcggt aatctccatt ctttgaaaat
    17041 cattggaagc aaaaaatgca tacttgaaaa tagatttgta aataattgga tggcagatta
    17101 tttggttttc gatgacctct ttttgtgaaa ggatattata cagttcaaaa tcttcgtttt
    17161 catagatatg aaaaaaggat cctttattca agcttgcttc attaacttta ggaaaaatca
    17221 tatttaatta cctccatttt cataaagtca tattaacaaa agctaaacca acttacatta
    17281 gcagaaaatg agataggttt tcgccttttt cgataacgat agtgtcgcta tctcttgaaa
    17341 cgttcttaga attgccctga gagacacaaa ttaggcgtaa ttctaataaa aatcttagaa
    17401 taaaaatttt tactgattta atttagaatg tttttaaaat aaaaatcgtt gccataacag
    17461 tgtattgaaa ggttttaaca atccagtaat gatttaaaaa aatctagatg tagcgtatac
    17521 tttgtttata gaatgtagtg ggaagaaata tatttttggg aggaaatcgt gatgtctaaa
    17581 agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc tcgttttaaa tccagagatc
    17641 aaagaaaagg aacgtatact tttgatagac gcaaagacag gcttagaaaa aggtcagtat
    17701 tatcctaaag tcataaataa tttggaacgt agtttacgtc cgttagcaat caggggagaa
    17761 ttgtctaaac cagtatcacc gttttatatg gagatatcaa caataggaaa atttgaaaaa
    17821 gaattaggtc gaggaatggc ttcggcaccg attacttttg ggcatttata aaaacgagtt
    17881 attcatctca atgaattaaa aagtatagtc aatctcataa tgcaggctag gttcatttat
    17941 ttgaacagag tctgtatttt tttattctaa ataaagaaac agatgtttct ttatattgta
    18001 ttttatcctt taattaacac aaaaacagct agtataaact aataatgtta attaaaagtg
    18061 tattttatga aactatcgtt atttattaat gttgcatttt tgtaagttaa aaattggaaa
    18121 tat
//
LOCUS       DACGLI010000058        18030 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.060, whole genome shotgun sequence.
ACCESSION   DACGLI010000058 DACGLI010000000
VERSION     DACGLI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.060"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(164..388)
                     /locus_tag="IXT22_002269"
     CDS             complement(164..388)
                     /locus_tag="IXT22_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAQ4863603.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="IXT22_002270"
     CDS             complement(586..2166)
                     /locus_tag="IXT22_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAQ4863604.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="IXT22_002271"
     CDS             complement(2567..3943)
                     /locus_tag="IXT22_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4863605.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="IXT22_002272"
     CDS             complement(4071..5189)
                     /locus_tag="IXT22_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4863606.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="IXT22_002273"
     CDS             5331..5765
                     /locus_tag="IXT22_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4863607.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="IXT22_002274"
     CDS             complement(5843..6376)
                     /locus_tag="IXT22_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAQ4863608.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="IXT22_002275"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="IXT22_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAQ4863609.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="IXT22_002276"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="IXT22_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAQ4863610.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="IXT22_002277"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="IXT22_002277"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4863611.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="IXT22_002278"
     CDS             complement(10101..10679)
                     /locus_tag="IXT22_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAQ4863612.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="IXT22_002279"
     CDS             11001..11471
                     /locus_tag="IXT22_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAQ4863613.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="IXT22_002280"
     CDS             complement(11579..12805)
                     /locus_tag="IXT22_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAQ4863614.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(13559..13759)
                     /locus_tag="IXT22_002281"
     CDS             complement(13559..13759)
                     /locus_tag="IXT22_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4863615.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13893..14501)
                     /locus_tag="IXT22_002282"
     CDS             complement(13893..14501)
                     /locus_tag="IXT22_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAQ4863616.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(14586..15056)
                     /locus_tag="IXT22_002283"
     CDS             complement(14586..15056)
                     /locus_tag="IXT22_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAQ4863617.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(15104..16018)
                     /locus_tag="IXT22_002284"
     CDS             complement(15104..16018)
                     /locus_tag="IXT22_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4863618.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            16164..16967
                     /locus_tag="IXT22_002285"
     CDS             16164..16967
                     /locus_tag="IXT22_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAQ4863619.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            17145..18015
                     /locus_tag="IXT22_002286"
                     /pseudo
     CDS             17145..18015
                     /locus_tag="IXT22_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
BASE COUNT         5417 a         3614 c         2952 g         6047 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat ctaaaaactt
    13501 cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca acaaattatt
    13561 ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc gtgaattcta
    13621 cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag aaatgaacaa
    13681 atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg ttgaaccatt
    13741 taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa gtaaccttgc
    13801 aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta ttttccaaat
    13861 tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa acgtttgttt
    13921 acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg gacattttta
    13981 tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt ctttccttcc
    14041 atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt ttccattaca
    14101 agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc ttctttaaaa
    14161 gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt aggttcgcca
    14221 ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc gccaccattg
    14281 ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa taattcttct
    14341 attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt cgtcacataa
    14401 gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata aggttccaat
    14461 gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt cctcctcaat
    14521 gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt cttcaattgt
    14581 tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc agtttcttta
    14641 aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg agtgatgatt
    14701 ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc ccccatgtcc
    14761 aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag tgcatgtgta
    14821 aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc aaacaataca
    14881 gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata ttggcgtgcg
    14941 agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag atagactagt
    15001 atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg cttcatgagc
    15061 caacctacct tattaaaaat tcttatttat catactctat atttcaataa ctttcatctt
    15121 tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg atcgtcacat
    15181 gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc ttttcaatct
    15241 cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc ttttcgctat
    15301 actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca atttcttgtt
    15361 ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca gcttttttga
    15421 tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata actggatcga
    15481 tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt accgaagaca
    15541 gtgtatcact taacaaatgc aaataactag attttatatt caaactttca tctgcttctt
    15601 gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct actgttagca
    15661 tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca acggttaaaa
    15721 acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt tctaaacgct
    15781 ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt gccccgtaag
    15841 aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca agagacaaac
    15901 tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc aaaaccacta
    15961 ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct tcctccattt
    16021 tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc accaatcatt
    16081 cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt gcaagtgatg
    16141 acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt tcctttatac
    16201 gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt gtctatcttt
    16261 tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa gtcttaaaca
    16321 acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca atccaaaacg
    16381 ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc attatcttca
    16441 catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg atggggaatt
    16501 ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat acaggcacga
    16561 cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa tctttaaaaa
    16621 acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca ctttggataa
    16681 aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg atcactttgc
    16741 tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa gctacttttc
    16801 ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt gcaacaatct
    16861 tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca ggaatcttta
    16921 tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa ataaagacaa
    16981 ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt gtcacagccc
    17041 cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc aaagttcttc
    17101 ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca gaaagaatca
    17161 tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact atagcgcctg
    17221 gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag atcagtttgg
    17281 gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa tggtagtggc
    17341 atccacagtg aatcgattac ggagcatgtc ttaggaatca tccttgggta ttctcgtggt
    17401 ctttttcaag cacaaaaggc acagagtgac atgaaatggt taggttcatc ggtccattac
    17461 caatctatcc aagggaaaaa aatactaatc attggaactg gccatattgg aaaaatgatt
    17521 gcaaaaaaat gcaaagcatt agacatgaac tgctatggaa tcaatacatc cggtcatcca
    17581 gcagaaggaa tggaaaagac tttttcttta aatcaactaa aggaagttct tcctgaagta
    17641 gatttcgtag tcaatatctt acctctaacg gaggaaacaa ctgggctctt tgatcagcat
    17701 atgtttgaac actttgatcc aaaatctgta ttcatcaatg ttggccgtgg tgcttctgtt
    17761 aagacacaag atctggtgca ggctttaaat aaccagcaac tttcctttgc agcattagac
    17821 gtttttgagg aagagcctct tccacaagat catcctcttt ggaaaatgga caatgtactg
    17881 attacttccc acattgcagg tttgacacct gattttcaaa agaaattaat ggctattttt
    17941 ttaaccaatc tgaaaagcta ctttgccacc catgagcttc aaaccaatca agtaaaattg
    18001 tctgcaggat attaatagct gaaaacaata
//
LOCUS       DACGLI010000059        17547 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.061, whole genome shotgun sequence.
ACCESSION   DACGLI010000059 DACGLI010000000
VERSION     DACGLI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.061"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(39..848)
                     /locus_tag="IXT22_002287"
     CDS             complement(39..848)
                     /locus_tag="IXT22_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4863620.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1141..2577
                     /locus_tag="IXT22_002288"
     CDS             1141..2577
                     /locus_tag="IXT22_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4863621.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2747..3943
                     /locus_tag="IXT22_002289"
     CDS             2747..3943
                     /locus_tag="IXT22_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4863622.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4005..4190)
                     /locus_tag="IXT22_002290"
     CDS             complement(4005..4190)
                     /locus_tag="IXT22_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAQ4863623.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4421..7735
                     /gene="dnaE"
                     /locus_tag="IXT22_002291"
     CDS             4421..7735
                     /gene="dnaE"
                     /locus_tag="IXT22_002291"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAQ4863624.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7903..8865
                     /gene="pfkA"
                     /locus_tag="IXT22_002292"
     CDS             7903..8865
                     /gene="pfkA"
                     /locus_tag="IXT22_002292"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAQ4863625.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8939..10723
                     /gene="pyk"
                     /locus_tag="IXT22_002293"
     CDS             8939..10723
                     /gene="pyk"
                     /locus_tag="IXT22_002293"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAQ4863626.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10758..11660)
                     /locus_tag="IXT22_002294"
     CDS             complement(10758..11660)
                     /locus_tag="IXT22_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4863627.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11846..12415
                     /locus_tag="IXT22_002295"
     CDS             11846..12415
                     /locus_tag="IXT22_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAQ4863628.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12473..12652
                     /gene="rpmF"
                     /locus_tag="IXT22_002296"
     CDS             12473..12652
                     /gene="rpmF"
                     /locus_tag="IXT22_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4863629.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12822..14243
                     /gene="gndA"
                     /locus_tag="IXT22_002297"
     CDS             12822..14243
                     /gene="gndA"
                     /locus_tag="IXT22_002297"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAQ4863630.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14436..15122
                     /locus_tag="IXT22_002298"
     CDS             14436..15122
                     /locus_tag="IXT22_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4863631.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15119..16624
                     /locus_tag="IXT22_002299"
     CDS             15119..16624
                     /locus_tag="IXT22_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4863632.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(17248..17391)
                     /locus_tag="IXT22_002300"
     CDS             complement(17248..17391)
                     /locus_tag="IXT22_002300"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863633.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            17311..>17547
                     /locus_tag="IXT22_002301"
     rRNA            17311..>17547
                     /locus_tag="IXT22_002301"
                     /product="16S ribosomal RNA"
BASE COUNT         5676 a         3058 c         3682 g         5131 t
ORIGIN      
        1 attgtcacaa cctctttttt gtggaatcta attctctatt atagtttaag tagtttttcc
       61 agataaacag ctaaaccgtc ttcctgattg ctcaaaggag tgacatcatt tgcaatgcct
      121 ttgagttggt cagtaccgtt agccatagct actccccaac ctgcataatc caacaattcc
      181 aaatcattat gctcgtcacc aaaggcaatg acgtcttttt gatcgataga caggtagtta
      241 gcaatctctt gcacgccttt tgctttttgg attccttttg aaacaatctc taagatggca
      301 gtaggtccac cccatgtccg aacatcgaca taactgccaa attgacgtgt taattcagca
      361 gatacagctc ctgcaaaacg tttgtctgtt cggacaagca aagatgtagg atttgtcgtc
      421 aaatttttag gagaaagcaa attcttctct cctggacgag aagaagcaaa aattttttca
      481 tcaaagaaat caaaactgtc aataaaaaaa gtatcacgat tttcagcagc gataaaatct
      541 aaatttagct gctttttttg cgataagatt tcaaaagcga tttcacgatt gatcaacgtt
      601 tctctttcac catcccagtg ctgattaggg atgtgtacta atgcgccgtt aaaattaacc
      661 atcggtgttg ttaattctaa ttgttggtaa aactgatggc tcattcggaa tgggcgtcct
      721 gtagcaatac tgacatgatg accggcattg attgcttttt ttagagtctc ttttgtttta
      781 gatgtaatca tcgaatcttg attgagggta gttccgtcca gatcgatggc aattaatttt
      841 ttattcaata agggtccttc cttcctcaac tagcatttgt tttagtctag catattttag
      901 gtaattaaca agagcaatca gctattccta acaaaaacta cagttatggc tatataaata
      961 gctaaacata agctaaacac gaacgttaag tattattttc gctttttttg ttaaaaaaac
     1021 gttgaaaagc gaatgaaacg tctatataat ttgaaattgt tcgatggatt tgccctattt
     1081 tacttatttt ttattattat agttttccat cagaaaaaaa ttcagggagt ggaacttttt
     1141 atggaaaagt ttttcggttt aaagaaaaac aatacaaatg tatcaactga aataatggcg
     1201 ggagtaacga cattctttgc catgagttat atcttattcg taaatccgac gattttgtca
     1261 gcatcaggta tgcccttcca agcagtattt ctagcgacaa tcattgcatc gattattggt
     1321 acgctggtaa tgggattgtt cgcaaatgta ccatatgctc aggcacctgg tatgggattg
     1381 aacgcatttt tcacttttac ggtcgttttt gggcttggtt attcttggca acaagccttg
     1441 gcaatggtgt ttatttgcgg attaatcaat atttttatta ctgtcacaaa tattcgaaaa
     1501 atgattattc gggcgattcc cgaaagtctt caacatgcga ttggtggcgg gatcggtatt
     1561 ttcgttgcgt atgtcggaat caaaaatgca ggattcttat ctttttcagc agaccagtca
     1621 gctatttcga gctctgtcgt tgaaggcgga aaagcgacaa atgttacgat aaatggtgga
     1681 atcgtccctg cgttagccaa ctttgacaac gctcctatct tattggctgt gattggtttg
     1741 gtactgacag ccattttagt tgtaaaaaat gtccgtgggg ctattcttat cggtatcgta
     1801 gcgaccacag tccttggtat ttttatgggt gttgttgatt taagttccat tgattggcaa
     1861 acgaattcgt taggtaattc atttaaagaa ttaggaacaa ctttcggtgc agcatttggt
     1921 tctgaaggca tgcaatcttt attcagtgat tcttccaaga ttcctcaagt attgatgacg
     1981 atcatcgcat tcagtttatc tgatactttc gatacgatcg gaacatttat cggtacagga
     2041 cgccgcacag gtattttctc aaaagaagac gagatcgcgt tggaagatgg tcgtgggttc
     2101 aaaacaaaaa tggataaagc actatttgcc gatgcgatcg ctacttctgt gggggctatc
     2161 tttggtacat cgaatacaac aacttatgtc gaatctgcag ctgggatcgg ggccggtgga
     2221 cgtactggtt tgacttcagt agtagtggca gtgctattcg cattaagtag tttattctct
     2281 ccactgatcg ccattgtacc aaatcaagca actgcgccag cattgatttt agttggagta
     2341 atgatgatgg cttcttttgc agacatcaaa tggctagata tggaagaagc tttaccggcc
     2401 ttctttgcat cgatctttat gggattgtgc tatagcattt cctatgggat tgcagcagga
     2461 tttattttct atacaattgt gaaagtaatc aaaggaaaat acaatcaagt ttctgttgct
     2521 ttgtggatcg ttgatatttt attcattatc aacttcatca ttctagcaac aatttaacta
     2581 aagagaaggg attggaacag tatttgttct gatctctttt tgttttacat aaaaagaacg
     2641 ttacatataa aatgaccttt gcgggatttt tctcttttta ctggcgagat cgttgcttgt
     2701 ttattcgaaa ataggtatga taaaagagac gaaagaggga tgatagatgg agattaattg
     2761 gagaaaaaat ttagtgattg cgtggattgg ctgttttttc actggtgcaa gtattagttt
     2821 agttatgcca ttcataccag tttatgttga gcaactagga acaccaaaag atcaaatcga
     2881 attgttttcg ggactagcaa tctctgtgac tgcttttgca tctgccgtgg ttgcaccaat
     2941 ctggggaaat ctagctgatc gaaaaggccg aaaactcatg atgatccgtg cagcagcagg
     3001 gatgacatta acaatgggat ctttggcttt tgtaccaaac gcgtattggc ttttgatcat
     3061 gcggttttgg aatgggattt tgtctggata tattccaaat gccacagcga tgattgcttc
     3121 acaggcacct agagaaaaga gcggatgggc gttaggaaca ttgtctaccg gagcgattgc
     3181 tggaaatctg atcggacctt caatgggcgg tgcactggct cagtggtttg gtatggaaaa
     3241 tgtattcttg atcacagggg ctttgttgat gatcacaacg gtattgacca ttttcttagt
     3301 caaagaagat ttccatccaa tcgagaaaaa agatctgata agcaccaaag aaattttttc
     3361 aaaaatggat catctctcta ttttgatcgg tctcttcatt acgaccttga ttttacagat
     3421 aggaatcact acgatcagcc ctattttgac cttatatatt cgtgaattga gcggaagtac
     3481 agaaaatatc ctttttgtca gcggcttgat tgtttcgata gctggtgttt ccgctgtctt
     3541 ttcttcaccg aaactaggaa aactagggga taagattggg aatcaaaaag ttctaattgg
     3601 aggactcatt ttatcatttt gctgttattt acctatggca ttcgtcacta caccgctcca
     3661 attaggtata cttcgcttta ttttaggctt ttcaactggc gctttgatgc cttctgtcaa
     3721 tacactgatc agtaagatta cgcctcaaga aggagtcagc cgaatctata gctacaatca
     3781 gatgtttagc aactttggac aagttttagg tcccatgcta ggatcgacag tcgcgcatgc
     3841 ttataattac agtgctgttt ttattgtgac aagtttgttt gttctgtcaa atattcttct
     3901 ttctttattc aactttcgta aagttcttcg cagcagatta taatggtggt gaggagtaga
     3961 aaataaaaaa gagcttgaga aatctcaagc tcttggctgt ttttttacga atgggcagag
     4021 gtttcttttc ttggcgcaac tgcaccaatc aaaaggataa tgacacccgc aatgaatgaa
     4081 atgattgttg tcaaagtaaa atcatatgtt ccgcttgtta atgcagcacc aatataaccg
     4141 actacttgac ctagaacgac agcccagaat aatgtaacga tatatcgcat aaagaacacc
     4201 tcttttctat cttaatttta ccagattttc tttgaatgta aagaaacgag accaaatctc
     4261 aataaaattt gagttcttgc gaaagaactc attcctacag attacaagca agcaaatgaa
     4321 gtggaataat caacttcagc gcctgctatc ttaatgaaag taaaaggatc aaacctttta
     4381 acgctagtga attttaacga aaaaaaaggc ggaatgcaag atgtttttcc cacaacttta
     4441 tacaattact tcttattctc ttttacaaag tacgatacgt attcgagaat atgtacaaga
     4501 agcaaaaaaa caaggctaca cttcattagc cataacggat aaagatgtct tatacggtgc
     4561 acctgaattc tatcgtattt gtgtagaaga aggagtacag ccaatcattg gattacatct
     4621 tagttatact tatgaagaaa aaaattatgg cttgcttgcg tacgcaaaag atgaaatagg
     4681 ttatcagcag ctgatgaaac tttccagccg aaaaatgatc caagaaaaat tggaacttgc
     4741 agaaatgaca gaaaccgacc atctagcgtt tgttgttccg gcaaatcatt ctgtttctga
     4801 ggctttcaat aaagaggata actttttcgg tcattggcag tttttacttg aaaatgtttt
     4861 tactagaaat ttttatatcg gcttgacaga aaacacgcct gatcaattgc ctgaatggta
     4921 tcagtatgtg ataaaagaaa attattcgct ttgtgcatta catcccatcg ctagtttaca
     4981 acaagaagaa ctttttgcac ttgaagtgat gaaacatatc aaagagggaa gccaaatacc
     5041 tttagaaaat ttatctgcat ctttaccact aacagcaaat gtctatcttc tttcagaaca
     5101 agaaatgatc aaacgattcg aaaaagcggg tctttcccaa gctgtaatag gcgcccagcg
     5161 tttagctgaa tcgatttcat ttgaattcca gttccatcag aaattacttc cgcattatcc
     5221 agttcctaat ggaaaacaag ctggagaata tttaagagag ttatgctatt cgcaagtgga
     5281 acgccgaatc actgactata caaaggaata ccaagaacgt ttggactacg agttatctgt
     5341 catccatcaa atgggattcg atgattattt cttgatcgta tgggatgtaa tggcttttgc
     5401 tcatagaaac aaaatcgtta ccggtgcagg tcgtggttct gctgcgggtt cattagtagc
     5461 ctatgtgtta gaaatcacag atgtggatcc attagaatat gatttgctgt tcgaacgctt
     5521 tttaaacccc gaacgcttta cgatgccaga tatcgatttg gatattcctg acaatcgacg
     5581 tgaagaagta ttgaattatg ttcgagaaaa gtatggacaa tatcatatgg cacaaatcgc
     5641 aacatttggc acaatggcag caaaaatggt tcttagagat gcagctagag tgtttggttt
     5701 atcgcaaagt gaagcaaacc gctggtcaaa agcaataccc aatcaattga aaatcacatt
     5761 gacccaagct tataaaactt cgcatcaatt agtagaatta gttcaggcaa gcgaaaaaaa
     5821 ccaactttta ttcaaaactg cagtgatttt agaaggattg ccaagacatg tttcgactca
     5881 cgcagcaggt gtagttatca gcgataagaa tctacttgaa ctagttccgc tccaacgcgg
     5941 ttctgatgaa gcttttctga cccagtatac gatgaatgag gtagaagcaa tcggtctttt
     6001 gaaaatggac tttttaggac tacgcaactt atcgattatt gattttactt tgaaagctgt
     6061 taagcgagta gaagggtatg agatccgatt aaaagagatc ccgctaaatg atgcaaaaac
     6121 gctgctcttg tttcaacgag gcgaaacctc aggagtattt caatttgaat ctgctggtat
     6181 ccggaacgtt ttacgaagat tagatccaga aaacatcgaa gatattgccg cagtcaatgc
     6241 attgtatcga ccaggcccta tgcaaaatat agataccttc attgccagga agaaaggaaa
     6301 agaagccatt cgctacccag atgattcact gatcccgatt ttgaaaaaca catatggagt
     6361 gatcgtctat caggaacaaa tcatgcagat cgcctcgact atggctggat ttacattagg
     6421 gcagtcagat attctgcgac gggcagtgag taaaaagaaa aaagacgtat tagatgaaga
     6481 aaagtcgcat tttgtatcag gagcattaca acagggatat tcggaaaaaa cagcagcgac
     6541 cgtatatgaa tatatcgaaa aatttgcaaa ctatggattc aatcggtcac atgcatttgc
     6601 ttattcattc gtgggattcc aaatggcgta tctaaaagcc catcatccag gtgctttctt
     6661 taccagcctg atgaattctg ttcggcataa cacatcaaaa ttgaaagaat atattgcaga
     6721 agcacgtaaa aataaactca aactttcctc gccgtccatt aatcaaagta attccagttt
     6781 tgagttggtc aataaggaag aaatcagatt cggactgaca gcgataaaag gtattcggcg
     6841 tgattttgta gaagatatat taaacgaaag aaaacaaaat ggcccgttcc agtcagtgga
     6901 tcaattcctc atacggatcg ataagcgttg gctgaaatta gagttactgc aatcactgac
     6961 agcagtagga gtttttgatg aattatctcc taacaggaaa caattgatgc ttgatctcga
     7021 aggaaaaatc caaaatatcg tttacagtgg tggaagtctt gacttgctgg gaatcatggc
     7081 attaaaagaa gaagaagtcg ctgactatac actagaagaa cgcttgaagc tggaagagga
     7141 gtacttaggt atttatttgt caggtcatcc tgcagaaggg tttgatcgtc ttcgtttagc
     7201 taaacaagtt cagctgatta cagatatcgt ccctaatcaa ccagtcaatt tattagtgat
     7261 gatcaaggaa gttagagaaa ttcggacaaa aaaaggagaa ctgatggcct ttgttgaagg
     7321 aaccgacagt agtggagaaa tttctgtcac agtttttcca actctttatc gtaaatatcg
     7381 taatttgttt gccgttgatc gagtgatctt tgttcaaggg cggagcgaaa tcagcaaata
     7441 taatcaggaa ctgcaactaa ttggagaaag ctttgctgat cctaaccagt tagaagccca
     7501 gtatccttca caaacttgct atttgcgtat tacagaagaa cgggaagatc ccgagataat
     7561 gaaacaatta caagtgattt ttcagaaaca cccaggatat ataccagtag ttatgtatca
     7621 cgaaaaaacg caacgaaaag tagttctgtc agatgcttat tgggtggatg acagcaagag
     7681 tataaagcgg caacttattt atctgcttgg cgaagataat gtggttttca aataacttac
     7741 ggtaaaaaat actacttgct ttcatttttt ttcatttttt tatccgtaaa tcaagacaag
     7801 tgagaaaaat aatgttagaa tgttagtcgt ggttaacgca aaaatggttg taaacctaag
     7861 tcatacttag gataaagtat tttaatgagg tgaatgttta ttatgaaacg catcggaatt
     7921 ttgaccagtg gcggagacgc acctggaatg aatgcagctg ttcgtgccgt tgttcgtaaa
     7981 ggtatttacg aaggactgga agtatacggg atcaattatg gttttgccgg tttagttgct
     8041 ggagatattc gtcgtcttga tgtggcagat gtaggtgaca agatccaacg tggtggtaca
     8101 ttcttgtatt ctgcacgtta tccagaattt gcaactgaag aaggtcaatt aaaaggaatc
     8161 gaacaattga aaaaattcgg aatcgaaggt ctagtggtta tcggaggaga cggctcttat
     8221 catggcgcaa tggctttgac aaaacgcggt ttcccagcag taggtattcc tggaacaatc
     8281 gataatgata ttcctgggac tgatttcaca atcggttttg atacagcaat caatacagta
     8341 ctagaatcaa ttgaccgtat tcgtgacaca gcgacttctc atgttcgtac attcgttatc
     8401 gaagtaatgg gacgcaatgc aggagacatc gctttatggt caggtgtggc tggcggagcg
     8461 gatgaaatca tcatcccaga acatgatttt gatatggctt cagttgctaa aaaaatccaa
     8521 gaaggccgcg atcgcgggaa gaaacattgc ttgatcatct tggctgaagg tgtaatgggc
     8581 ggaaatgaat tcgctgagaa actttcagaa tttggtgact atcatacacg tgtatctatc
     8641 ttgggacacg ttgtccgtgg tggagcacca agcgcacgcg accgcgtgtt ggcaagtaaa
     8701 ttcggtgctt acgctgtcga attgcttcaa gaaggaaaag gtggattatg tgtcggtatc
     8761 catgacaacg aaatcgttgc gtctgacatc attgatacac ttgaaaacaa caaacataaa
     8821 ccagacttat cactatatga tctaaataat tcactttcat tttaagagtg aaagaaacca
     8881 agctatttaa gctgtgtaca gctttaaata aacaaaattg aatgggagag ttttttaaat
     8941 gaaaaaaacc aaaatcgtta gtacattagg accagcaagt aactcagtag aaattatttc
     9001 tcaattgatt gaatctgggg caaatgtctt ccgctttaat ttttctcatg gtgaccatga
     9061 agaacaatta tcacgtatga ctatggtccg tgaagcagtt aaaaagacag gaaaagatgt
     9121 cggtattctt ttagatacaa aaggagctga aatccgtaca actgttcaag gcacaacaga
     9181 agctgatttt ggtcgtgcag gatacatcaa atttgaagta ggagatcaaa cacgcatctc
     9241 tatggatcct gaacatgtag gttcaaaaga aaaaatcgcg gttacttacc caggattatt
     9301 tgacgatgtt cacgttggcg gacacatttt atttgatgat ggtttgatcg atatgcaaat
     9361 cattgaaaaa gacgaagcaa accgtgaatt agtcgtagaa gttaaaaatg caggtatgct
     9421 aggatcacgt aaaggggtaa atgcaccagg cgtttctatt agtttgccag gtattactcc
     9481 aaaagatgct gacgatattc gttttggttt agacaacgat atcgacttta tcgctgcaag
     9541 ttttgtacgt aaagcacaag acgttctaga tatccgcgaa atcttagaag aaaaagacat
     9601 gactcatgtt caaatcttcc ctaaaatcga atctcaagaa ggtatcgaca acattgacga
     9661 aatcatcaaa gtttctgacg gtgttatgat tgcccgcgga gatatgggtg ttgaaatccc
     9721 agctgaacta gtaccaatgg ttcaaaaacg cattatcaaa aaatgtaatg ctgctggtat
     9781 cccagttatc actgctacac aaatgttaga atcaatgcaa gaaaacccac gtccaacacg
     9841 tgcggaagct tctgacgttg ctaacgctgt atttgatggc acagatgcaa caatgctatc
     9901 tggtgaatct gcaaacgggg actacccagt tgaagctgtt tcaacaatgg cacgtatcga
     9961 ccaagaagct gaaaatgcat tatcagaatt aggtacattc caattgaacg aattcgataa
    10021 aacagatgta actgaaacaa tcggtttatc tgtagctcgt gctgcaaaaa atctaggcgt
    10081 gaaaacaatc gttgctgcaa ctgaatcagg atacactgca aaaatgattt caaaatatcg
    10141 tccagatgca gatatcttgg ctgttacttt tgacgaacgc acaaaacgtg gtttgatgtt
    10201 aaactggggc gtttacccaa cagttgctga aaaaccatca acaactgatg aaatgtttga
    10261 actagcagct aaaaaagctg ttgaattagg tttcgcatca gaaggcgatt taatcttgat
    10321 cactgctggt gtaccagttg gtgaacgcgg aacaactaac gtgatgaaaa ttcaaatgat
    10381 tggttctaaa ttattagaag ctcaaggcgt tggacaaaaa tctgtcgttg caaatgcagt
    10441 tattgcttca tctgctgaag aagctgtaaa aaaagcaaaa gacggaatgg ttctagttgt
    10501 accatcaact gacaaagaat atatgcctgc aatcgaaaaa gcagctgctg ttatcgttga
    10561 agaaggcgga ttgacttctc acgctgcagt tgtaggaatt gcacaagata ttcctgtaat
    10621 cgttggtgct aaaggcgcaa caacaacaat tacagaaggt gaattgatta ccgttgattc
    10681 acgtcgcggc atcgtttacc gtggcgaaac aacagctatc taatttagct taataaaaaa
    10741 taaaaacagc tcttctttta cgaagagctg tttttttgtg ctgtaacgaa ttcatggata
    10801 acttggacta cttgttcttg aagaggcgtg acgatctgct gtgttcgttt tgccaatgaa
    10861 atcaagaagc gaggctgaac ttcatctgaa agagggaggc aaactaaatg atcttcagga
    10921 tggacagcaa tctctgccaa aaaaccgata cccacatttt ctcggaccat actctttaaa
    10981 atcgtcaagt cattgctttg ataaacaact tttggatgag tatgtgtttg tttagaaagc
    11041 ttagtgaatg ctgcggggtg gacataatgt tcgttcaata gtacaaactg ttcatctgct
    11101 atatctttga aagagacagt atcctgcttg gaaagaggat gtgtaggtgg cacgacgatc
    11161 atgaaacgtt tgtccaaaag taactctgtt tctaaatatt gatccacgat tggctgtgtt
    11221 gagcctaata cagctaaatc gatcctccct tgtcggatca tcccgtataa gtcccgagag
    11281 cctccatcgg taatctcaat ttgattcatc aattcatgct tgataaagta acttgacagt
    11341 ttaggaaagt attcattgcc gataatagga ggcatgccaa aacgaagctt tttcttttgc
    11401 aactgagtga tttcagctct tgcagtagaa atctcttgga gaatggtttg tgcatggaga
    11461 aacagctgct ttccagaagg cgtgacgatt aattcgtgat gcgatcgatc tcttgtaata
    11521 agtacggtgt caaactcttt ttcaagacgt tgtaatgcat atgtaatagt aggttggctc
    11581 acacggaaat aattagccac tttcgtaaaa tttttttgtt tgacgatttg gacatagtat
    11641 tcgatatctt tcgtgttcat gaagatcatc cgctccttta atggaataat gattattgta
    11701 aatgattctg aggatgatag caaacagagg ctttctaata aagatttttc tgttttttta
    11761 tgaactgcaa ggtgtcaaga aaatttcatt gacaacatgc tttttgccct gtataattgc
    11821 ttttgttgct taggagtgat gaaaaatgaa atggtcttta ttggaattga gaaaatacca
    11881 ggagacaccg ttaacttttc atgagacgct cgacttgaaa gccgctctca tgaagcgaga
    11941 caatttaata cttgatgttg cgccagtgga agtcgaaggt ttggtctcag ttgataagaa
    12001 aggctatatc gttcattaca ctgtgcagac gactttgaca gttccttcaa cacgttcact
    12061 agaacctgtt gaactgccca tggatttttc tgtagacgaa gtattcatga cagaagaaca
    12121 attccaaagt agagatgaac aaatgtctgc ggatgagatt ttgctaattg aaggtccatt
    12181 attgaattta gcagagtcga ttgaagacaa catcttattg gcgattccaa tgcgggtatt
    12241 gacaaaagaa gaggaagcag caacagaact tccaaaaggc aatgattggg aagttgtttc
    12301 cgaagaagaa taccagcgca gaaaaatgga agaagccgag aataaaattg atcctcgtct
    12361 tgcaaaacta tctgaacttt ttgattctaa atcaaaagac gacgataaca agtaagattg
    12421 gaatatattg tgtctaattt agatacaaga ctttacaagg aggtgtagca aaatggcagt
    12481 accagctaga agaacatcaa aagctaaaaa agcaaaacgt cgtacacact acaaattgac
    12541 aatcaaaggg ttaaacgaat gtccaaactg tggtgaaatg aaaaaaagcc atcacgtatg
    12601 tgcaaattgt ggttactatg atggtaagga cgtaatgtca aaagaagctt aatacatttt
    12661 aattagaaaa tgtaaaacct caaggctaac catggagcct tgaggtttat ttttttgtag
    12721 tcggtaaata aaaaatatgt tgttctttag tttgcaatgt agccgtgtta agctataatg
    12781 taagagatta gggagaaatc ccgtatgtag gaggagttca tatgtcaaaa caacaaatcg
    12841 gcgttgtcgg tatggccgtt atgggtaaaa atctagcctt gaacatagaa agccgcggct
    12901 attcagtggc tttattcaat cgtacagggg ctaaaacaac cgctgtagta gaagaacacc
    12961 cagataaaaa tttcaaagca acatatacaa tcgaagaatt tgtagaatct atcgagaaac
    13021 cacgtcggat cttgctaatg gtcaaagcag gaccggcaac agatgcaacg atccaagagt
    13081 tgcttcctca ccttgataaa ggcgatattt tgattgacgg aggaaataca ttctttaaag
    13141 atacgatgcg tcgtaatgaa gagttagcca actctggcat caactttatc ggtacaggcg
    13201 tttccggtgg tgaagaagga gctttaaaag gaccttcaat catgcctggt ggacaaaaag
    13261 aagcctatgc gctagttgca ccaatcttag agcaaatttc tgcaaaagca gaagacgaag
    13321 caccatgtgt cacatatatt ggcccaaatg gagccggaca ttatgtgaaa atggtacaca
    13381 acggtattga gtatggagat atgcaactga ttgctgaatc ttatgactta atgaagaata
    13441 ttttaaacct ttcagtagaa gaaatggctg atatctttaa agaatggaat caaggcgaat
    13501 tagacagcta tttgatagaa atcactgctg acattctgac acgtaaagac gatgaaggaa
    13561 caggtaaacc agtagtagat gtgatccttg atgcagctgg gaataaagga acaggtaaat
    13621 ggacaagcca aagcgcgctt gacttaggtg tgccacttcc attgatcact gaatctgtat
    13681 ttgcccgcta tatttctgct tataaagaag aacgcgtaca agcaagcaag attttatctc
    13741 gtacgaacga ttttgagttc acgggagaca aaaaagaatt ggtcgaaaaa atccgagaag
    13801 cgttgtattt cagtaaaatc atgagttatg cccaaggatt tgctcaatta cgtgtcgctt
    13861 caaaagaatt tgattgggac ttgccatttg gtgaaatcgc aaaaatctgg cgcgctggat
    13921 gtatcatccg agctcgattc ttgcaaaaaa ttacggatgc ctatgacaaa aatcctgaga
    13981 tcgaaaattt attgctagat gattacttcg ttgaaatcac gaaaaaatat cagcaatcag
    14041 tcagagacgt cgttgccttg gctgtccaag ctggcgtacc tgtaccgact ttctcatcag
    14101 ccatcgctta cttcgattca tacagagcag aacgtctgcc tgcaaatata atccaagccc
    14161 aacgcgatta ctttggcgca catacctatg aacgtgtcga caaagaagga atcttccatt
    14221 actcatggta ccatgaagaa taatagtctt tcggctgtta ggaaatgaga aaataaaaag
    14281 aggacgaaag agctgaagtc gattgttatg agtagacttc agctcttttt taaaattgct
    14341 atccatgata aaatgactat agatttttaa gcatattatc ggtataatga tagagttttt
    14401 aaaaagccag tagaatagaa aggataaaat aataaatgag caatattcta atcattgaag
    14461 atgaaaagaa cttggcacga tttgtcgagc tagagttgaa gcatgaaggg tataacgcag
    14521 aagtccacta caacggccga actggtttag atgcggcatt aaataatgag tgggatgcca
    14581 tattgttgga tctgatgctc ccagaattga acggtttaga agtctgcaga cgtgtacgcc
    14641 aagtcaaaaa tacaccaatc attatgatga ctgcaagaga ttctgtgatc gatcgtgtat
    14701 ctggacttga ccacggagca gatgactaca tcgtcaaacc atttgctatc gaagaattat
    14761 tagcacgtct tcgtgcattg ttgcgtcgaa tcgatattga aggcgataaa aatgtggcta
    14821 aacaaactac tattacttat cgcgatttga ctatcgaaaa agaaaaccgt gtcgtacgtc
    14881 gcggaaatga agtaattgaa ctaacaaaaa gagaatacga gttgctgctt actttaatgg
    14941 aaaacgtgaa cgtggtatta gcacgtgacg ttttactaaa taaagtgtgg ggatacgaaa
    15001 cagaagttga aacaaacgta gtggacgtat atattcgtta tcttcgcaac aaaattgacg
    15061 ttcccgggga ggaaagctat atccaaactg tacgcggaac aggttatgtg atgcgctcgt
    15121 gataaagccg aaaaaatcgg aaaaaagaga actgaaaggg ccctccttga caatcaagtg
    15181 ggcctttgcg agttctttct tcatattcgt tgtgtttaca attttcgctg tcattaccta
    15241 taaatcatct atcaatctga ttgtggcaaa agaaagaaac aatgtagagc gtacgatttc
    15301 agaagtagct tctcgtttgg ctaactcgga tgaagaactg acattagtaa atacgtatcg
    15361 taatctgacg aaagcgacaa atgacggaga tgaggtcgta gatcatactt cactggtcga
    15421 aggaaactta atgaagatcg attcctttat agctgagcta gggcagccat caatggatct
    15481 ttatgtttat gatttggacg agaacttgat ttttaaaacc catgaaaaca gtcgaaacct
    15541 gattcagact acacgtaaag ttccaacgat cgttacacta gaaggaaaaa ctggcttttt
    15601 atctatccag cctatatatt ctaaaggtac aagagaaaag atcggctatg cgcaaagctt
    15661 ctatgaatta tcttctttct atgatattcg aaataagcta ttattgactc ttattgtttt
    15721 agaagttgtt tctttgatct taagtagtat tttaggtttc tttttatctt cttatttctt
    15781 aaaaccactc aaggtactca gagatacaat ggatactata cgtaaagatc cgcaatcaga
    15841 tatccacatg cctgaaatcg acacaaatga tgaattggca gatttagctg aaatattcaa
    15901 tgagatgctt gaccgtatgc gtttgtatat tgaacaacaa gagcaattcg tggaagacgt
    15961 atctcatgag ttaaggacac ctgttgcaat tattgaaggg catcttagtc tgctaaatcg
    16021 ttgggggaaa gatgatcctg agatattaga agaatcatta agcgccagca tgcaagaaat
    16081 tagccgtatg aaaagcttag ttcaagagat gctagactta tcaagagcag aacaagtaga
    16141 tgttcattat gcgaatgaaa caactaaagg aaaagaagtc acctatcaag tttataataa
    16201 tttcaagata ttatatccag actatgtgat cactttagat gatgatttga caaaagaagt
    16261 gaccctgcaa atttatcgta atcactttga acaattaatc attatcatat tggataacgc
    16321 agtaaagtat tcaactacac gaaaagaagt ccatatctct atttcttcca ctctgaatga
    16381 atttgagatc gcgattcagg actttggcga aggaataccc aaagaagacc ttaataagat
    16441 cttcaatcgt ttttatcgag tggataaagc aagagctaga acgaagggtg gaaatggtct
    16501 ggggttgtct atcgctaaac aactggttga aaactataaa ggacgtatct tagcagaaag
    16561 tgtagtaggg caagggacaa tttttagaat ctttattcct atcgcaaagg cagaagacaa
    16621 gtaaagcatg tgctttactt gtttttttat atatccaaca aagaataagg tacaaaatac
    16681 aagcaagtta gaaattcagg gatgtcatta taaaaaaaac tagcgaacaa ttaaatagaa
    16741 taacatccgt taattaaacg taagtagctt ttagatgaac gaaaaaacaa tgaaatgctg
    16801 taatattcgt gtttaaaaat aataaataaa aatagggaat tttctattgc aattttataa
    16861 agagattgct atattattat ttgttctaaa tgattccttt aaggtgtcac taaaaattat
    16921 aaaaaatagg gttgacgcac ttttgatgtc atgttataat aacgaagtcg tttggatgag
    16981 gtagctaata aagcttgatt ttatcgaaaa aaacttcgaa aaagttgttg acaaataaca
    17041 ataaagatga tatgataatc aagtcgctgc taatgagtga caaagacgtt tagaaaaaat
    17101 aaacaaagaa gttgttgaca ttctcttctg aatctgataa gattaaagag ttgttgaaac
    17161 aaaaagatta gacctttgaa aactgaacaa agtaagacaa accaaatgtg tagggcgtct
    17221 tgattcaatt caagacaaca aacattttta acaagcaagc aatatgctag caaacaaatt
    17281 gagcttaaca atcgcaagat tgttcgaact ttttatgaga gtttgatcct ggctcaggac
    17341 gaacgctggc ggcgtgccta atacatgcaa gtcgaacgct tctttttcca ccggagcttg
    17401 ctccaccgga aaaagaggag tggcgaacgg gtgagtaaca cgtgggtaac ctgcccatca
    17461 gaaggggata acacttggaa acaggtgcta ataccgtata acaatcaaaa ccgcatggtt
    17521 ttgatttgaa aggcgctttc aggtgtc
//
LOCUS       DACGLI010000060        16590 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.062, whole genome shotgun sequence.
ACCESSION   DACGLI010000060 DACGLI010000000
VERSION     DACGLI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.062"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(82..789)
                     /locus_tag="IXT22_002302"
     CDS             complement(82..789)
                     /locus_tag="IXT22_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAQ4863634.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(868..1206)
                     /locus_tag="IXT22_002303"
     CDS             complement(868..1206)
                     /locus_tag="IXT22_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAQ4863635.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(1317..2279)
                     /locus_tag="IXT22_002304"
     CDS             complement(1317..2279)
                     /locus_tag="IXT22_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAQ4863636.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(2294..3625)
                     /locus_tag="IXT22_002305"
     CDS             complement(2294..3625)
                     /locus_tag="IXT22_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4863637.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(3633..4313)
                     /locus_tag="IXT22_002306"
     CDS             complement(3633..4313)
                     /locus_tag="IXT22_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAQ4863638.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(4532..5011)
                     /locus_tag="IXT22_002307"
     CDS             complement(4532..5011)
                     /locus_tag="IXT22_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAQ4863639.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(5138..6817)
                     /locus_tag="IXT22_002308"
     CDS             complement(5138..6817)
                     /locus_tag="IXT22_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4863640.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            7365..8867
                     /locus_tag="IXT22_002309"
     CDS             7365..8867
                     /locus_tag="IXT22_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4863641.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8880..9542
                     /locus_tag="IXT22_002310"
     CDS             8880..9542
                     /locus_tag="IXT22_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863642.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(9643..9846)
                     /locus_tag="IXT22_002311"
     CDS             complement(9643..9846)
                     /locus_tag="IXT22_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4863643.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(9957..11141)
                     /gene="iadA"
                     /locus_tag="IXT22_002312"
     CDS             complement(9957..11141)
                     /gene="iadA"
                     /locus_tag="IXT22_002312"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAQ4863644.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(11298..13037)
                     /gene="yfcC"
                     /locus_tag="IXT22_002313"
     CDS             complement(11298..13037)
                     /gene="yfcC"
                     /locus_tag="IXT22_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4863645.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(13810..14424)
                     /locus_tag="IXT22_002314"
     CDS             complement(13810..14424)
                     /locus_tag="IXT22_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4863646.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(15030..15407)
                     /locus_tag="IXT22_002315"
     CDS             complement(15030..15407)
                     /locus_tag="IXT22_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863647.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(15707..16588)
                     /gene="galU"
                     /locus_tag="IXT22_002316"
     CDS             complement(15707..16588)
                     /gene="galU"
                     /locus_tag="IXT22_002316"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4863648.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         4809 a         3574 c         2831 g         5376 t
ORIGIN      
        1 ttattccaaa taaatggtat tcaatcagct aactctcggt attagctcag atcaaagcgc
       61 tgatttcaca acttctttat tttaatctct tcggttgccg ccgaacaata agatcaagcg
      121 caacagctgc aggaatgtcg aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa
      181 tacgtgtctt gccatcggta cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg
      241 gattgctcgc cgagacgcgt taaattcgac tggtaatgtc accaattgga aaagtaatgc
      301 taaagaaaaa gcgaaaatcc cgatattgat taacgtagag ttccagctaa gcaatacacc
      361 taccataatc aaggggaacg aaatcatcga accaaagtta gctgctggaa caagtgctgc
      421 acgaatcttc aatgggacat aacccgaagc atcttgtacc gcatgtccgc attcatgagc
      481 tgctacacct atcgcagcaa ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat
      541 cttattacct gaattgtagt tatctgtgag atctccggca atttgttgaa caccgacatt
      601 atttatctgt tgactttgta atatatattg tgctgcttgt gtaccagtca cattgttttt
      661 gcttctcact tgatcgtatt ttcggaaagt actattgacg tacgctgacg caattccgga
      721 aataactaat ccaagaatga ccaaaagaaa tgtcggatct aaaaaaccat acattccata
      781 accatacatt ttcgtttcac tccttttcgt ttactttatt ttatcattag tagtaggaaa
      841 agaatgtgaa aagaccttga atattcttta attctttttc acaaattccg atttcagttt
      901 catcggtcca aatccttcta ccttgcaatc gatattatga tcgccttcta ctaaacggat
      961 gttcttgact tttgttcctt gtttaatggc acctgacgca ccttttactt tcaagtcttt
     1021 aatcactgtc acgctatcgc cctctaacag acggtttcca tttgcatcta ataccactaa
     1081 tccgtcttct atgacagttt cttgttcttc tttgttccat tcgttcccgc attctgggca
     1141 aatcaacaag cctcgatctt catatgtgta ctctgagcca cattctgggc aatttggtaa
     1201 tgtcatcttc tttctccttt aaaatcttta gtgagcacta ttgtaacgga aaaagaagat
     1261 cttgaaaaga tacatttgtg atttttacta caaaaggcac gttttcgaac gaagtatcat
     1321 tctgtttttc tgctcttata cgattggcat atatcttgga tctctttata gatttcctct
     1381 acttctgcta aatcttttgc attcgcacca cttgctaatg gatggcctcc tccatgatgg
     1441 cgtttagcca attcattgat gatcggcccc ttagaacgta aacgtacgcg gtaataccct
     1501 gaaggctgct gaacaaaaat cccccaagcc agcacttcgt caatcactcc aggaagtgaa
     1561 acgatcgaag ctgtctctga atcatcgatt ccatatttat caagaatttc ttgcggaagg
     1621 attattcttc ctgcaccatt ttcatccacc tggatatttt gataaagata accggaaagt
     1681 ttagcgactt tcatcggcat ttgttcaatc tctctgttca aagcacttgc atcaaatgga
     1741 taatttctca atatcgaagc aatctctaat gtacgggacg tcgtggaggg atacaaaaag
     1801 cgccctgtat ctccgacgat tcctgcataa agtaaccgtg cagccttaac gttcatcttt
     1861 aaagattcag gaaacatcaa agcaaattct gcaatcatct cactacagct acttgctttt
     1921 gtatttaccc acacaagatc tccataaggg tcatcattgg gatgatggtc gattttgatc
     1981 agtttttctg ccaactgata tctttgatca ctgattctgg gtgaattagc tgtatcagtc
     2041 acgatgacta gcgctccttg gtagaagaca tcttcaactt cttgcatttc tgctaaaaag
     2101 cgaagccctt caatcgtttc acctacttga cgtatttctt tttctgggaa actttcccgt
     2161 aatagttcgg ctaatcctac ttgtgatcct aatgcatcag gatcagggcg caaatgcctg
     2221 tggataatga ttttatcgta tttttttatt gtatctacta tttcttgctg tactgtcatt
     2281 tcactcctgc tttctaagaa cgttccatta cttgacaaac aacgattgct ttggaaacga
     2341 tggtgttttc aataaacact tcgatatcca gtttagcgga acgtctgccg atttccaata
     2401 cacgtggacg aatgtctaat tcgctttcca attggatcag ccgcaaataa tgtaggttca
     2461 cttgttcaat caagatattt cgtttttggt tcatcaccat tgttttttgt gcgacatcag
     2521 aaatgatttc gctaagtacg ccaaaagaaa tggttccaac gccattgacc atttgtggtg
     2581 ctactacgaa tttgaactta gggttttcca aacgatttcc ttcacggtca gtatcaatcg
     2641 tatggatatt tccagatatc tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga
     2701 caagctgcat cgctttcatt acatcttgcc gggtaatcaa gccttccaat gtcaagtcat
     2761 cggaaacgac cggcatgact tctagcccat cccagatcat ttgatggcta acagaggcaa
     2821 tactcattgt tttctttaca ctgattggtt ctttcgtcat cacccgatcg atgatctggt
     2881 ttggcgattt ccctaaaaca tcttttgccg taacaatccc catcaaacga tgatggcggt
     2941 tgacgactgg aaaacgcgaa tgctgcgttt cttctgacaa acgctgataa tcagaaatcg
     3001 tatctgtctg ctgcaaataa tgagtctttt cagctggcat atagatatca ctgacaagca
     3061 tgatatcttt tttgatcaat tggtcgctta acgctcggtt gatcatggtt gcgactgtaa
     3121 atgtatcata agaggtgcgt aagatcggca tttcaagatc atcagctagc tttgcaatct
     3181 cagcagtcgt attgaatcct cctgtgatca atactgcggc gccatcttcc aatgctaatt
     3241 tttggacttc cgcccggttg ccgacgatca ttagtgatcc tggcgtaata tagcgttcca
     3301 tggcatgttt agtcatcgcg ccgatgacga atttattcaa gaccttgtct aatcctgccg
     3361 ccccgcctaa aacgtcccct tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa
     3421 tatgtttttt taatttgcgt tcgatacgga tggtccctac tcgttgaatt gttgaaacta
     3481 gtccgacatt ttctgcatct ttgattgcac ggtacgctgt tccttcactg acattcaatt
     3541 cttttgcgat gcttcttaca gaaattcgat tgccaacagg taaactttca atatattcta
     3601 aaatcaaatc atgttttgtc gccattttct gcctacactt ccagcgtttc cgagacgctc
     3661 attatttttc cttcactatc ttccagtaac tctacaaaag attcgggatc ttgttcaatg
     3721 acagggaaag tattgtaatg gattggaact actttcttgg cacgaattgt ttgcgcagcc
     3781 tttgctgcat cttctggccc catcgtatag ttatcgccaa tcggcaagaa agcgacatca
     3841 atatcgaatt cttctgcaag caatcctaga tcactgaaat aagcagtatc ccctgcatga
     3901 taaatcgttt ttccttctgc ttgaataata attccgctag gctcgcccat atactgaacg
     3961 ataccgtcta cttcatagct tgaactatgc tgtgcatgta cgaattttac cacgccgaat
     4021 ggaaacgcat gttttccacc gatattcata ccgaatgaat ctactcctct gctgttcgca
     4081 taatcagcaa tctcaacaat actgataatt gtggcttgat tttcttttgc aataggaatc
     4141 atatctccta tgtggtcact atgaccatga gtaatcagca accaatctgt ctttacttct
     4201 tctgcagtta agtctgtcaa tggatttcct gtaataaacg ggtcaatcat cacgcgttgg
     4261 ccattttcca tttcaattgt taaacaggaa tgtccatgat acgtaatttt catattttac
     4321 acctcgcgtt ttctctgtat cttttttatt aaaaacgatt tcatcacttg cacatcaatg
     4381 aaaaaatata gctgctaaat atattttcat tggattgata gtacagtatg tacaaagcaa
     4441 ttgtaacaga taatacagga tgcaccaagt accaagcaga tataatctca agtttgaggt
     4501 ctctgctctg cttagcttct cttctcgtcc cttaactaat taaatcagcg taaataggat
     4561 ggacgatctt ttctaaatcg gctactttta tccgaaggct tctcccgatt tcaccgcttg
     4621 acacaattac ttcttctttt tcttttaaag aactgtctgc taaaaaacaa taatcaggat
     4681 gtgcgagttt tattccaata ggggtgtttg ctccgtgggg atatcctgta tgcattaata
     4741 caaaatccat tccaggaaaa ccaactttac gatctttcgt cacttgtctc gtttttttgt
     4801 aatctaagtg atcgttcaaa ggaatcaatg cgatgatcac cccagttttg tttcctttca
     4861 ctacgagagt tttacatatc aaagctggat caatccctct tttttgtagt tcttctgtga
     4921 aagattcttc taccacatga ctaaaatcaa gtggttgata gctgatcttt tgttcttcta
     4981 aataacgttc gacttttgtt tgactcatca ttgattcact ccctttattc tatcgtttat
     5041 tataaagcga gggatgctgt attcaaaaat tatttgtttt tcgcaaaaaa agagcaagac
     5101 gagcactcta tagagaggtt catcttactc tttttgttta ttttttattt cgacgttgag
     5161 tagcttccat aatgactggc aagatcactg ggcggcgttt tgtttgttca aataagtaac
     5221 ggcctaattg atctcggatg tcttgcttta atttgctcca ctcaaaatca ttgctttcta
     5281 aatgtttctc aacgattgtt tcaatcatat tgctgctttc tttcatcaga tcacggctag
     5341 cttttacgta aacgaatccc cgtgaagtaa tttgaggttt tgaaatgatt ttcttttctc
     5401 gccgactgat agtgacaacc gctacgaaaa tcccgtcttc tgacaagatt tttcgatcac
     5461 gtaaaacaat gtttccgata tcacctatgc ctaatccatc aatcattaca ttttctgcac
     5521 ttgtagttcc tgcaacactc atacgcttgt tcttatattc cagcacgtct ccgcgtccag
     5581 taatatagat atttttgtat ggcatcccta ctgcatgagc caaatctgca tgagcagcta
     5641 attcacgata ctctccttga actggcacaa aatatgttgg tttcatcaaa ttgatcatta
     5701 attgcaagtc attaggattg gcatggccag aaacgcgcat attctcagag atcaacttca
     5761 ctgttccacc agctcgataa atgatatctt ccgttttcgc cacgatggtt tccatcgcga
     5821 tgcttggcgt agtagtgata taaaccaaat ctccttcttc aatcttgaca ttacggtgtg
     5881 taccgtttgc cattttttgc agagacttga tgggttcacc cattcggcca gtttctaaaa
     5941 tgatcagttc ttctggatca tagtttttca tgtctttcaa cgtaacaagc agatcttcac
     6001 ttggtaattg aagtttttct aaacgcatcg ctgtgcgaat aattcgttcg aaatcttgac
     6061 cagtcaagac aacttttcgt tgtgcttttt ctgctgcatc caatacttgt tgcactcgtt
     6121 gcaaattact tgctacacaa gcgacgatga tacgcccttc ccaatatttg atcgtatcaa
     6181 atacttcatc tgctatttgg gcttcagaag ctacaggctg aggattttct gcatttgccg
     6241 attcacttag taaggctaag actccttctt tgccgatttc cgccaatcgt gcataatctg
     6301 tttgatacat tgggatagcc gtttggtcaa atttaaaatc tcccgtataa acgatactac
     6361 cttcttttgt tttcagattg atccccactg aatctggtat cgtatgagtg gtacggaaaa
     6421 agctcactac tgtttcacca aagtctattt ctgtatgctc atctaccaca tggaaatcct
     6481 taaatccttt ggctgcttca ttacgactga cattcaattt tgctaactcg atcgtcaact
     6541 ctgtcccgaa tactggtaca gaaatttttg acaacaagta aggaagtgcc ccgatcgcat
     6601 ctgcatgtcc atgtgttaaa aagacaccag ctacacgatc aatgttttct tctaaatacg
     6661 taaaatcagg gattacgacg tcgatcccca acaactcatt ttcaggatat tttagcccac
     6721 aatctaaaat aaaaatatcc tcgcccactt ctgcgacata catgtttttt ccattttcac
     6781 gaacgccgcc taatgggata attttaatgg tactcacaaa cttcacctct tcttatgaca
     6841 tccaagttta aagatgtcga ttttcttctt tatctaaata tatgagccat tccaatgaag
     6901 catatgcaaa atcactattt ctcaacttat ggagaatcag caggaaaatt accagcacat
     6961 ccgcgttctg acagttggat gggcatttta ttttggatat acttcattaa caaaatggat
     7021 cttttgcgaa acgctatagc cagaatactt atataagtat tcagctgttc cccattatta
     7081 tacaacaaat aaactaaatc gctagtatca gcaattgtta gaacaactat gcacgtaaaa
     7141 atccctctgt agcatctagg atttcttttg ctattcctct ttcatttctt cttcgtcggt
     7201 ttgaaacata cttttttcat tttaccacat tttttgcaat aactatagtg actttttata
     7261 tatacagaac ctcatgttga tggtgtgcaa acagcataag atttaagcta gctttaagat
     7321 aggttgtcta ttatcaaatg catctactag gagggatgca aaatatgaat tttatgaaac
     7381 gtgcatggaa aagtacaaaa gtaaaatggg gacgttcatt gttattgttt gccgtgttca
     7441 cagccattct tatttttgtg ctagctggcc tcacgattcg aagcgctgca gaagaagcag
     7501 cgaatcaagc acaaaaagaa gttggagcaa cagtgacttt aagtgccaat cgagaagctt
     7561 catttaaaaa acaggaacaa acttcttcaa gcggttctac cactgaagaa cgtccagatc
     7621 caggcagttt ttctcttaca ccagtttcct taacggacgc ggaaaaaata gctgaattag
     7681 ataatgtaaa gagttattcc tttgaaagtt ccgcctcagc tatggcaaaa gatggaataa
     7741 ctgccatcac tagttctgat tcaagtgaag acagttcaga aactactgat gcaggcggtg
     7801 aacctgctgg aggaatgggc gggaatccgc aaatgactca agcagacttt caaatcagtg
     7861 gtgtgtcagc aactgcacaa aatagtaatt tttctgatgg aacagcaaaa atcacggatg
     7921 gtgaaggaat agatgacagc gacaaaggca caaacaatgt agtcattgat tctactctag
     7981 cagaaacaaa tgacctggca gtcggagata ctttcacaat cacgagtact gaagatgaag
     8041 ataccactta tgaaatgacg atcaaaggaa tttatgaatc cagcgaaaca agcggcagta
     8101 tgggtatgaa attcaacttc atgaatccgt cgaatacact ttacacttct tacacttttg
     8161 caaatgaact aaatgggaca tctgacgata acacgataga ttctgctatt tacactctat
     8221 ctgatccaga taaaatggat gagtttctca aagaagctga gaagctgatc gacacagata
     8281 catttagctt acaatcaaat gattccatgt atcagtcaat gttggaacct ttaaacaacg
     8341 tggcaagttt ttctaaaaat gttgttttac tagtgactgt agccggtatt atcatactta
     8401 ctctgatcat tatgattacc attcgggagc gtcggcatga gttaggcgtc ttgctatctt
     8461 taggagaatc cagaagtaaa atcattctcc aattgtttac cgaagtggct atttgtatga
     8521 ttcttgcatt aggagttgct tcgcttagcg gaaacgtcgt cgcgaatgcc gtgggacagc
     8581 agctacttga ccaacagaca gaaaccacga cacaaaacca gcaagctcct ggcggtggac
     8641 aaatgccagg taacagacaa gaacaaggcg gtcaacgcga tggtcaacaa ggaaccacga
     8701 ataatccatt tgctgtttct gatcaagtca gcgaattgga aatcaatgtc aaacctgcac
     8761 aattgggact attagccgga gtagcatttg gaatcagtct gttttctgtc tttttagctt
     8821 ctatagggat attaagatta aacccaagaa aaatcctatt aaactaaagg aggaatttga
     8881 tgttacggac agaacaattg ggattttggt atcaagatcc gcaagatgcg ctttataaag
     8941 atgtagaact gaatttcgaa gctggaaaaa tgtacgctat tttaggagca agtggttctg
     9001 gaaaaacgac ttttctttcg cttatttctg gactagatgc accaaaagaa ggaaaggtat
     9061 actatcaaga tcgttcactg aacaaaatcg ggttaagaag ttatcgtaaa aatgatgtct
     9121 cgattatttt ccaagcttac aacttgcttc cttatttatc ggctctagac aacgtcatag
     9181 cagcaatgga aatcactaag accaagcaag agaattatcg acaagttgct ttagatcgac
     9241 tggctcgtgt aggaattgat gaaatattag caaaaaaaca ggtgaccaaa ctttcgggag
     9301 gtcagcagca gcgagtcgct atcgttcgtg ctatctgctg tgaacatcaa ctaatcgtag
     9361 cggatgagcc tactggaaat ctagatgaaa caacttcaca agatatcgtc aaacttttcc
     9421 aagaaatcgc ccatgaacaa aatcgctgta ttatcatcgt gactcatgag attgaagtag
     9481 caaaaagctg tgatgaagtc tttgaactaa aaaataaaaa atttcaaaaa atcgaagttt
     9541 aaaaaacagg ataatgatca aataaaaaat ccgaaccata tctgtctcgc agatatggtt
     9601 cggatttttt atttgcttga ttcaattagt aataagtggt ttttattttt tttcgtcttt
     9661 tcgagaaaac ttgtctttga cttcgtcgcc taaatttcga gctttttctt tgatgtcagc
     9721 acctagtgat tgtgctttcc cttctgtttc tttgctcttg tcgtctgttg ctttgccgta
     9781 tgcttctttt ccttcaccga ctactttatc tttcatatct ttagaacgtc cttttaaatc
     9841 tgccattgtg cttcctcctc ttagtttgtt tattgatcta ccttcagggt aacatcaaca
     9901 acagatacag acaaacagaa cgctcgtttt ctaaaaaaga tagttagagc tgttgattaa
     9961 aaactttttt cgaaagtccc ccatactttg acttcttttt cttggaccat tatttctcct
    10021 ttagcgataa ctgtatcaat atcaagcgtt tctttatcca agatacacag atctgcatca
    10081 gcaccaattt cgatttttcc ttttttatcc aatttcaata tacgtgctgg attactggtt
    10141 atagctcgta aggcgatttc caaagggata ctttcttttt gcacagcttc tttgatccct
    10201 actagcaatg ccttggcact tcctactcct aaccctagga aatgattgtt ttcatcaaaa
    10261 taaggcaagc ttccttgtcc atctgaggtc atcgtgaaat tatctaaaga aacatcttcc
    10321 tcgatcaatc gtttcagtgc tttgctgaag cgaacttcac catctgtctt ctcccaaaaa
    10381 tcaggatctt cgctagcagt gaagtcaatc gtgccaccac gtttggcaaa tgccacgcaa
    10441 gcttcaaata attctggtgt gcgatttgca tgagtaggca aaaattgtgt gatcggaatt
    10501 tctgtttctt ctacgattcg tgtcaatagc tctagctttc tttttcctcc gcctaagtgg
    10561 acattgatga tcccagcttt tccggataac atgcctccta cacgagcatc tgctactgca
    10621 cgagcgaact cttcaaaact tggctgagaa gaacggtgat cggatactgc gatttctccg
    10681 attccgataa ttttatcaat tgtcaaaaag tctttgatga tagaatctgt tactgttttt
    10741 accggcaatc ggtacgaacc ttcgtataca taagtggaga ttccttctgc ttccagacct
    10801 ttcgctttgc tgatcaacgc agtcatatct ctaccttctc cgtctgttcc caaacaaccg
    10861 acaactgtcg ttacaccagc tgtagtcaat tggctcaatg tgacttctgg cgttcgattt
    10921 tgataaccgc cttctcctcc tccacctaaa atatggaaat gacagtcaat gaaacccggg
    10981 gttagtactt ttccctcacc tgaaagttct tctacttcca ctccttcgta gccgccttct
    11041 agctgttctt ctacagccaa aatcttccca ccggcaatca gtacatccat ttttcctaag
    11101 taatctggtg caaacacttc aatttgtcga atgattttca tacatttttc ctctttcttt
    11161 aagtataact gatgatagga tcttaaaaaa taatccaaac gataggatct ttactccttt
    11221 gattttaccg taaaatgacg gttcttggag tccttatcta ctgtttggat tactttttta
    11281 tttacaggtc tccagtacta ctgcagacct attgcaatgg caatcatgat gaaaatagtt
    11341 cctaaaacaa acaggaatcc ttgcatcttg atttggaatc ttgcccattt tgcccattcg
    11401 atccgtgcaa cacctagcac accaatcaag ctggctgata cgggtgtaaa agcgtccata
    11461 aaacctgaac caagctgata agcaagaact gctacttgtc tggatacacc tactaaatct
    11521 gccagtggag ccatgattgg catagtcaaa gctgcttgtc ctgaatttga tgtaacaacc
    11581 aagttgaaca aactttggaa gatgtacatc gcccaagcac caatgacagc tggaacaccg
    11641 gtcaacgccg tcccgatccc atgcaaaatc gtattcaaag ctgaaggaac agatgcatca
    11701 gatcctccca agacaagaag aatccctttg gccataccta ctacgattgc tgtaccagct
    11761 aaatcagctg caccagattg gaaagaagaa gcgatgtcat tgactttcat tccatctaat
    11821 ttgaaaagaa cagcaatgat tccagcaact aatcccatca caaagaattg agaagcgatt
    11881 tctggaatgt aatagccttt ttgagtcacg ccccaaacga tccagacaag gacaactaac
    11941 atctctaata agatcaattt atgcccaagc atgaattttt tattttcatc agatgtcttt
    12001 ttgatatgag aacggaaata atcatctgat ttgtaagtca acgaactttc tggtttttta
    12061 cggatttttt ctgcatatat catcatataa ccagcggcta atgcagtaac aactacccac
    12121 ataatcaatc ggaatgtcgc accagacaac acggggattc cagcaatccc ttgagccacc
    12181 gctacgctaa acgggctcat ccaagaggtc gcatttccga cttgagatgc gacataagtc
    12241 acggttactg ctacgatcga gtcatatcct aacgcaatga caaatggaac catcaccatt
    12301 gagaatggaa ttacctcttc tgccatcccg aatgtagcgc caccgaatga aaaagcaaag
    12361 aataatagcg gtaaagctaa acgctccagt cccttagttt tactgataaa cgcatagata
    12421 cctgcgtcga tcgctccggt acgcataata ataccaaaag cacctccaac aacaaggatc
    12481 aatgcagcga tccctacagc agatccatac ttatctccag atactagtcc ttcaaaaaca
    12541 aaatttaaga aaccaaagcc gccaaaatca tctgttcccc atattttggc tgttttatgc
    12601 aattttttag aagtatcata gatattttcg ccgtactgat cgtaaagcac atcatctgtc
    12661 aaggagattt catctagttt ttcctgcgta agattttttt ctccgtcagc aatgactttt
    12721 tccaatcctt tttccggaac atccagtttt tcacgttctg ctggatgatc ttgcagttct
    12781 tctaattgat caaacacata cgacttatcc agctcgtaag cataacggaa ggaatcttga
    12841 cgtaaaacag tacgagtact tgtttcgcca tttgcatctt tgtattcaat atcttgcgtg
    12901 ctgaactttc ctgctggaac gacaaaagtc agtatccatg caaagatgac tacaccaaaa
    12961 ataatgacat acgtatgggg tgtcgataat ttagtgaagt cgcgtttcgg ttttcctgaa
    13021 gaatttgttt tcttcaaatt tatttcttcc tttctttttt cagtaatttt gatgaataaa
    13081 aaatggataa tcaaatgaat tatacagtaa aaatgacatt tccacatgaa taatttatta
    13141 gaaaatcact tttttctatt ttgctttttt tctcctatgt atgattattt ttttctcttt
    13201 ccatttatat taagtatttt atttctctgt ttttccttaa aattcttttt ttatttttag
    13261 attagagaaa atctcgtcct gtttttttca ttttacaatc attgaaaaat tgaatttcat
    13321 tgcaaaaaaa ataataaaca cttataaata tccattatct atccttcaat ttttgtgtat
    13381 tttatttcta ttagaaaaag gtatcctgtt ggacaatttt gttatatcag gtaaacttca
    13441 ttgcaataat gataacaaat gtactataat tactttgtaa agagttttgg ggaagactct
    13501 ttcatcaacg tgtattaaga gacaagaaag aatccatatg gattctttct tgtctctttt
    13561 tccactactt tttatttttc tgacactaca tattcttata actcatttct cataactgtg
    13621 aaacaactta taaaaataac aaactttaaa caaaacaagc ttaaaatcaa agatgatcca
    13681 tcttaaaata actaaaacaa aaaaagtagt cgttgttaat cctcattaat aatcgttttc
    13741 tttttttcaa acgctccatt tttatgtgga acattatttt tttaaggaac tttgtcaaca
    13801 tgtggataac tattttccac ttgtgtcctg gactagctgt tttgctgtaa aatacaaaac
    13861 ttgctgcagc aaaaagatcg ttgcaagaga ggctgttccg cagatcgctg gatctagatt
    13921 tggcaaagtc aagactgcat catgtaaatt ggcgtggttg tccaaaacca aatcagcaaa
    13981 ttcaaataat cgcaaaccac tgctatgttg cgatttgata cttcgtgaca aatcaaatcc
    14041 agtaacaatg attaatggat gaccattttc tttgatccac tgagctagtt cgatgattgc
    14101 cgggtttctt ccttcattcg aaagaagaag aaaaatgtct tctgatttga cagaaagctg
    14161 atcaataatt gcctgtcctg caccttctag cgtttcatag acacctccgg ctggattttc
    14221 aatcaatata cttggtacaa gatccggggt ttgatcccaa aattcaaatg ctacaccact
    14281 tagtgtgcgg ctagcatata tctgcaatct accaccttga ttaatttgtt tcgcgatcca
    14341 agtgccagct tgaagcatca gcggctcttc tatccttaat ttctcttcca attggtgata
    14401 atagtcaaaa taacataaac tcatttatct ctcccgccta gctatacttg acatgaatag
    14461 aaacagctgc ctaatctaag gaagtacata aaaaaacagt agttagacag taacacatgt
    14521 ggtctttgct gtttcaaaca caaaaaaggc attgaacgaa tacgcccaat accttgacat
    14581 agcaaataaa acaacgtgca gaccatggaa aatatctaca taggggtaga attttcaccc
    14641 tagattaggt acaataaatt aggtcgatgc actgcattga ctatggcaaa atgatcggtc
    14701 agggtgtatg tgtgtgactg gtcattccct gattcttagc gccaactaag ggtcagggag
    14761 ccttttttta ttcagctgtt tctatctgaa tttattgtaa gtaatctctt atccaagtgc
    14821 aagcaagaaa atacaaaaaa acattggtat gatttatata tatataaata acataaaaaa
    14881 aggaatggct tatcccgata caacaagcat tcctttaaaa aagattcttt tatataagtg
    14941 aaaaaagctt ttttccacca attaaataaa tctctcatct caatagttta tccattattt
    15001 tatctttttt tgcgtatacc tactaaatat taccgtcttc ttctcgttct tctactttgt
    15061 tcgagagaat ctgtactaga aaaagtagtt gtatgtctac cttttctgcc tatccgagac
    15121 tttcttttca tatatgggat ataaatgatt agatacagta cagcaaaaaa taaagcaaat
    15181 acgcaagctt cccaactacc taacgccaat tcaaccatca aggtagcaac cccaacggat
    15241 gctgcatacc agataaaaat cagaaacgtt tctttttttc tgaccatgcg aaacatgata
    15301 aatagactaa taagcaatag tggcaacaca aatatccaat tgcttccttc catcagccac
    15361 ttgagtatat caagcagcga ctgtgcaaca gcgactaatt ttcccatagt gaacacacac
    15421 ctttttttat aattaaaaaa ttcgcctttt tattctacta tgaatcttct ggcttggctt
    15481 tcatttctct tatgtaatca ttttctttta tacaacttaa aaaaaaatta aaccattagc
    15541 ataatatttt ctgaatctat tcacgaaagt ctttttctat ctttcgtttt ccacgactca
    15601 actgatctag agtcaaaaaa ctaaaacgac agttgcgcaa atgacgcaca agctgccgct
    15661 ttaataacaa atagcctttc attctcagca ggccacttat ttccagttaa ctttctgttc
    15721 ttagcttttt actcaactgg ataatatatg cacttaatga agtcccaatt tccgaatgtt
    15781 gaagtccata ttcaatattt gtcttcatat atcctaactt atcgcctacg tcgtatcttt
    15841 ttcctttaaa ctctctcgca tagaccgcct ctgtctggtt aagagtctga agtgcatccg
    15901 ttagctgtat ctcgtttcct gctcctggtt cttgagtttc taatatctca aatattttag
    15961 gagtcagtag ataacgtccg ataatggcta aattacttgg tgcttttccc atttcaggtt
    16021 tttctacaaa cccttttact ctgcaacgac ccttttcgct atctgtttta ggatcaataa
    16081 ttccgtattt agatgtttca ttttctggta cacgcatgac ggcaacagcg gaagcttgtg
    16141 tttcttcata atccatcatc aattgttgag tcaatgggat atcatctttc atcaaatcat
    16201 cccccagcat gacgacaaac ggttcatttc ctataaatgc ttttgcttga agcacggcat
    16261 cccccagtcc tcttggatga gattgacgga tgaagtgaag attgacttga gtcgtttctt
    16321 caactaaagc gagtaattct gttttttcct tttcccgcaa attgttttcc aattcgatat
    16381 ttgcatcaaa gtgatcttca atgggtcttt tttcttttcc cgttacgatc aagatgtctt
    16441 cgattcccga atccaatgct tcttccacaa taaactggat cgttggttta tccacgattg
    16501 gaagcatttc ttttgccatg gcttttgttg ccggcaaaaa acgtgttcct agcccagcgg
    16561 caggaatgac tgcttttttg accttcactt
//
LOCUS       DACGLI010000061        16387 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.063, whole genome shotgun sequence.
ACCESSION   DACGLI010000061 DACGLI010000000
VERSION     DACGLI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.063"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            103..1146
                     /locus_tag="IXT22_002317"
     CDS             103..1146
                     /locus_tag="IXT22_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAQ4863649.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1319..1543
                     /locus_tag="IXT22_002318"
     CDS             1319..1543
                     /locus_tag="IXT22_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863650.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1546..1803
                     /locus_tag="IXT22_002319"
     CDS             1546..1803
                     /locus_tag="IXT22_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863651.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGFQADNDSKKVE"
     gene            2020..2895
                     /locus_tag="IXT22_002320"
     CDS             2020..2895
                     /locus_tag="IXT22_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863652.1"
                     /translation="MTTNKRWSELVQNTVKKVMPDGYHFNYIQCSQTTESIYFSILNE
                     NRLYYFRVSSHHRKKREDNVTTFLSGKYNGFKELSEAIGEYLKSNRFVRISDKHILIL
                     LLYLNNSFKLFWRDDTFYYIENGMDIYSGINGILKHYIKALLRYGVLYQEDLSNQIKI
                     SNSGKSLLAKYKKLLSPIYKGIDMEAVNSETLFNLVVDEKFANEFFKSKKIERLNNLF
                     PENAIKAYVDNNKSRLYNWFIPKRLRGKIKIGDQVKVINLNHTKIVTVTELYIAEKED
                     ITKMKPVIKILDNKE"
     gene            2905..3699
                     /locus_tag="IXT22_002321"
     CDS             2905..3699
                     /locus_tag="IXT22_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863653.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSRRLRITVEYGTNESATELKQRYLDTRREASKKYDDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            3728..4846
                     /locus_tag="IXT22_002322"
     CDS             3728..4846
                     /locus_tag="IXT22_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863654.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLKTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            4879..5199
                     /locus_tag="IXT22_002323"
     CDS             4879..5199
                     /locus_tag="IXT22_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863655.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            5454..6143
                     /locus_tag="IXT22_002324"
     CDS             5454..6143
                     /locus_tag="IXT22_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863656.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            6180..6347
                     /locus_tag="IXT22_002325"
     CDS             6180..6347
                     /locus_tag="IXT22_002325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863657.1"
                     /translation="MVNEVETLLASFFENGHVNDEWRKEEPKRVNAYIARLKRFIDKY
                     KENSDKFSKDK"
     gene            6367..7995
                     /locus_tag="IXT22_002326"
     CDS             6367..7995
                     /locus_tag="IXT22_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863658.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            8046..8369
                     /locus_tag="IXT22_002327"
     CDS             8046..8369
                     /locus_tag="IXT22_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863659.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLTALGRSRP
                     SSIGG"
     gene            8373..8522
                     /locus_tag="IXT22_002328"
     CDS             8373..8522
                     /locus_tag="IXT22_002328"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863660.1"
                     /translation="MPFGMRVTVGNSKTEKINAIISLIPSMMVQFQCEGAQVKDIELA
                     PQVKL"
     gene            8853..9053
                     /locus_tag="IXT22_002329"
     CDS             8853..9053
                     /locus_tag="IXT22_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863661.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            9187..10413
                     /locus_tag="IXT22_002330"
     CDS             9187..10413
                     /locus_tag="IXT22_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863662.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            11263..12588
                     /locus_tag="IXT22_002331"
     CDS             11263..12588
                     /locus_tag="IXT22_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4863663.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            12581..12928
                     /locus_tag="IXT22_002332"
     CDS             12581..12928
                     /locus_tag="IXT22_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863664.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            13279..14100
                     /locus_tag="IXT22_002333"
     CDS             13279..14100
                     /locus_tag="IXT22_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4863665.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            14120..14680
                     /locus_tag="IXT22_002334"
     CDS             14120..14680
                     /locus_tag="IXT22_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAQ4863666.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNKTHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            15588..16355
                     /locus_tag="IXT22_002335"
     CDS             15588..16355
                     /locus_tag="IXT22_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAQ4863667.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
BASE COUNT         6306 a         2143 c         3217 g         4721 t
ORIGIN      
        1 aacaacgatt atgatcttaa aacaatcgtt tatgtaattg gcaatcttac gaataatttt
       61 catgcaataa tgacaataaa aaatgaaaag gggtaaaatc aaatgaaaaa atttttagta
      121 ggaattctat tcacaatggg gctagtatta ttatcacctt cagtttcagc agaaagctct
      181 atttccatgt atcgtatgta taatcccaat agcggagagc atctatacac tagaagcgtt
      241 ggagaaagag acaatctgaa acgttatgga tggcattacg aaggtgtcgc atggcaagct
      301 ccaacaagtg gtactcctgt ttatcgtttg tataatcggt ataacggtga acatttttac
      361 acagttgatg ccggagaaag agataagatt tcacacacag gatggacgta cgaaggtgtt
      421 gcgttctatt cctacaacgg agcaaataga gttcctgtaa cacgtttata taacaaatac
      481 gtgaattggc atcactacac gttagatcaa aatgaaaaga acgtaattag taaacaaggt
      541 tggaagattg aaggtacagg ctggtatgca atgccaaaca gcgtaccaaa tcctacacct
      601 gctccaagca ctgaaaaagt gttgaacgtt cctgttgtat ggcaaggaaa tacaatgtta
      661 tgcgaaggag cttctttatt agaaggttta cactacaaag gtgtagccac aaatcaaagc
      721 ttaaccagtt ttgtaaacta tatgccaaaa gctaatgaca ataatcctta tcatggttac
      781 tcaggagagt ggcgtcataa cgttaatgga acgtatcaag gcatgatggc tgacccagta
      841 gttaaatggg caaaaaacgt tggcggtaat gccgtcaata tcactggttc aggaacgaat
      901 ggaatcaaga atgaaattcg caatggtaat ccggttgtaa cttggattac ttataactat
      961 gctacgccag agttcaaaca aatgccttgg ggtcgtgcag tatggaatgg acatgtagtt
     1021 ctcgtggatg gcttcagaaa tggtgcatac catgttgttg accctgtatt tggcgcaaaa
     1081 tggatcaatg caagcacgta tgagagagca tttaatgtga ctggaatggc ggttgctgta
     1141 cgttaattga tagaattatc aactaaatga aataagagct taattactga aatggtaaat
     1201 aggctcttat ttttttagag gaaatttttg taatacgaat ctataacaaa aaatattgaa
     1261 tgtagtacac aaaagtggta tattaaaatc gtagagatta tgcgaagagg tgattttgat
     1321 gaaccaaaga agaagaaaaa ggttagaaga aataagcgag cgactttccg agctaaagga
     1381 tgagttagaa gtaattcaag aagaagagta caaagaaaat atacctaaaa atctacaggg
     1441 atcagaaaga tatgaaaaag cagaagaatc cgttgatcaa cttgaagaag ctgttgatgg
     1501 tttatccgac atattagaat tgattgaaga tatagctagc tagagatgat taatgaagat
     1561 ttcaggagtg agaataaaat gattgatatt tcactgatag agaagctact tttttcaaat
     1621 aagtacacag ccaaagagtt ggctacaaga tggcaaatat ccgaatcagc tattaaagcc
     1681 tatcgtcaaa ataagggaag cgtaggatgg cgtgattgga aaggaatcag cattggaaaa
     1741 gcagaagaca taatgaaacg tgaaggattt caagctgaca atgattctaa aaaagttgaa
     1801 tagtttaata gtcgccaaga aaagtaccag gacgagggga aaggtagatt acaaaggaaa
     1861 acacttttaa ataaacttcg caaaagcatc aggttatgag tggctagggc tatacgaatg
     1921 tgatgaaaac aaagggcttt aatgtcaaag aaaacgcaat agggggggaa caaaattttt
     1981 aaaaaagata tttatgtttg gtttaatgga aaaaaatata tgactactaa caaaaggtgg
     2041 tcagagctag tacaaaatac agttaaaaaa gtcatgccag atggatatca tttcaactat
     2101 atacaatgct cacaaacaac tgaaagtatt tatttttcaa tattaaatga gaatagactc
     2161 tattatttca gggtaagttc acaccatagg aaaaagagag aagataatgt tacgacattt
     2221 ttatcgggaa aatacaatgg cttcaaagag ttaagtgaag ccattggtga gtatctaaaa
     2281 agtaatagat ttgtcagaat ttctgacaaa catatattga tcttgttact ttatttgaat
     2341 aatagcttca aattgttttg gagagacgac actttctact atattgagaa cggcatggat
     2401 atttattctg gtatcaacgg catattaaaa cattatatta aggcgttact tcgatatggg
     2461 gttctttatc aagaagattt aagtaaccaa attaagatta gtaattctgg aaagtcatta
     2521 ctggcaaaat ataaaaaatt gctttctcct atctacaaag gaatagatat ggaagctgta
     2581 aattctgaaa ctttatttaa tttagttgtt gatgaaaagt ttgcgaatga attttttaaa
     2641 agtaaaaaaa ttgaaagact aaataacctg tttcctgaaa atgcaataaa agcttatgta
     2701 gataataata aatcacgatt atacaactgg tttattccca aacggttgcg aggaaaaatc
     2761 aaaattggcg atcaagtgaa agtaattaat ctaaatcata ctaagatcgt taccgtaacg
     2821 gagttgtata tagctgaaaa agaagatatt acaaaaatga aaccagttat taaaatacta
     2881 gataacaaag agtgagtgga aaatatggta gcaaaaaaga atactctaaa agaagcttct
     2941 gaaaaatatc aagatatgaa aagacgagga ttaataccaa aggacaaaaa aggtatatgg
     3001 agagaatttg ttaaggaagt cagtagtgat cgaagtggcg gtgactttgt tggacgatat
     3061 acagcaaaag gttatagcag gcgcttaagg atcactgttg aatatggaac gaatgaatca
     3121 gctacagagc tgaagcaaag gtacttagat acacgaagag aagcttcaaa aaaatatgat
     3181 gatttcaaga gcagaggtct aattcctaag aagaaaaagg ggatttggcg tgagtttttc
     3241 aaagaagaag atagcaatcg gaataaggga gacttcattg gacgatacac agcaaaaggc
     3301 tacactaaga atttagggat caaggttgaa tacggaactg gtgaaagttc atgggaattg
     3361 agaaatcgct atttaaatac attgttagag aaatataaag cagaattatt ggagttgttc
     3421 gatgttaatg attttatcga gatggctgaa aagtatggtc atgaagaagg ttttatgatc
     3481 aatgacatta tggttattga taattttacg gatttattag cacttgcgaa aaaagcaagg
     3541 gatttaagag aaacgcagat gtatctattc agaaataaaa acggaagaaa ccggagaact
     3601 gaatcgagtg agattgaaga ttactatgat gcctttacac acgatctggg agcctttgta
     3661 gacgagataa gtggtgtaat gaacaaatat agggtctaga ataaaaaagc cggagatgag
     3721 cagataaatg ggaaacaata gcatatacac acctgaaatg cagaataaaa ttaaaagact
     3781 tgtcggatta gggtggatga caagaggaaa attagattct tttagtacga tcaaatatct
     3841 tttgatggac atttaccgtc agaacaagca aacaggaata cattttttgg gctatgataa
     3901 gccggaagat gcacctttct ttgttccaag ttcagcctat agagccagta cctccggtag
     3961 catgtataac ttggatttgt ttgaggaagg agcaaagatg atcgaatatg atttcaacga
     4021 agcctattcg aggatcatga gaaattatcc tttgccgtca aacacttatt tgaaagcaaa
     4081 atataataca gatcaagcta ttttgagagc gataaataga ccaaaagtaa gaccgtatga
     4141 aaatttaaaa acgtatatgt tctttttggt taattttgaa ggaacagcca aagaaggaac
     4201 atatgctaat ccaaaatcac agtcgatgtt tgcggattat ggcgaaaatc ccaaaacagc
     4261 taatgagcct atttggttat cggagattga gctaacactt atccttgatt attatgatat
     4321 taaagagatg gaagtcctag atagccacac atttttgacg aaaaaaggat tactcaaaga
     4381 atattttgaa agaatcgagc cattaaaaac tgatcctgat acgttgaagc tttataaaaa
     4441 tcttagaacg aaagtatttg gtgctatcgg acaaaaatca ttaagagaag gagaaacaag
     4501 caccttcgat aaatacagta tgtataatcg agcgtattcc tccatggtag caggcgtatt
     4561 tagagatcgt atggttagat atgaacagaa atacgttcat agcgcatatg ggctattaaa
     4621 aattcgtact gatggattgt atttcagatc cgaagtacca gagtttgaag agctgtataa
     4681 acttggagta gttaagaaaa aagttcatac aatatccaaa gaagaagtcg aaaaagcttt
     4741 agaatttaaa aacaaaggat ttgaaaataa gggctccttt gggaaatcta aagatgaagt
     4801 taagggtgtt gtgatagacg atgatttcga gtttgatttt gactaaatac tctttggaaa
     4861 agatggtagg aggtaaatat gaagaagaaa attgtggaag gaaatgtagg tgttattatt
     4921 ctaaaagatt caactgacta tgctaaatca atggcactaa aagacgaaaa agttgcacgc
     4981 atggataaag atttagttga atttctgatg gatgatacag aaagattaaa aggggatcag
     5041 tttttgagtt taatgaaaga caaaggctta aacacatatg gtttatttga ttataagaaa
     5101 ttagctatag agtgggtaaa agaaggagaa atatttttta ttgaagaatg ggaaggtact
     5161 gagaacttag ttcttcatca gtatcttttg aaagcttaat ctaagtaaaa cagttctgac
     5221 tagttatgct tgtcagaatt tcaaaggaag ttttccataa ccatcatcat tcaaaaataa
     5281 aggatttgaa aataagggtt cctttgggaa atctaaagat gaagttaagg gtgttgtgat
     5341 agacgatgat ttcaagtttg attttgacta gatttttttg caatgtttaa gagtaaacaa
     5401 ggtaagaact aagatcatga agattgagag taaagaagat agaggacgaa tgtatgagaa
     5461 cacactatat ttatttagaa gataaaattg tagatgaaat tccggcaaaa agtcgagaac
     5521 aagctagaaa attatttatt gaaaaataca aagagatcaa tggagatagt gaagttccaa
     5581 aagtggtcgt aacagttaga aaaaggcaaa caaaaaagag aagtacgttt catgtcagcc
     5641 ctgatatata taatcttata gagcgacata gaagtgaaga taatatttct atctctcaat
     5701 atattgctac agttattgat gaattgattt caggaaagta tgactatgct tttgattttg
     5761 agggtgaaaa ggattacaaa agtgttgctg tctttcaatc tgattttgag aagctaaaaa
     5821 actatgctgg caggagaaat gttaattttg caagactact agaagagttc tactccgaag
     5881 agttgggagt aggaaatgaa tacaagagag aaacttatgc gaaattgtct cataagttat
     5941 cccaagcgct taaagaagtg acagaagtta aagcggaact agatgctaaa cttgaagaag
     6001 tgaaaaaata tcaaacagag aggaagaaca acatgaagaa tcaagtggaa tttgacgaac
     6061 agaaagaatt tgaaaaagca agaaaacgct ataacaaaat tatgaatgaa cttagctatg
     6121 aacacttaac agttcatgaa taattgagtg agggtacaga aaaatatacg atcgcagata
     6181 tggttaatga agtggaaact cttttagctt ctttctttga aaatggtcac gtaaacgatg
     6241 aatggcgaaa agaagaacct aaaagggtta acgcttatat tgctcgatta aaaaggttta
     6301 ttgataaata taaggagaat agtgacaaat tttctaaaga taaataagga gagagtgtga
     6361 ttacatttgc cagaaatcga aggaatattt tcgccaaaaa taggtaaaaa acagttagat
     6421 ttcagcagtt ttccgagcgt aaatagagat tataatctag gtgatgaggt acagatacta
     6481 aatattgatt tcaaagaact agacttcgct gttgctgttt ccaacaaacc caaggcattg
     6541 gaacgagtga aaaaaatata ccaagagaat gatcaaaata tcaaaaatat gatcaaaaag
     6601 tatagacgag ataattcaaa agttgaagac gttttattca acggtacggc aaaacatgat
     6661 ttgaatgttt atatggcatt aggagtggct ttgtactgta attcaattaa tcagacagat
     6721 attttggtta atatcgtgag gaatagctat caaaaaatat taaaaataag tagcgaaaca
     6781 aacccttatt atgcaatgaa atatcttggg gataatttat taaatgataa aaaattgatg
     6841 cacaacactg aagagctgtt atctaatttg gctgcgatta actttctatt caaaacaggt
     6901 tctgaagatt attttataga taacgtacta aaaggtgctt acggaacagc attttatccg
     6961 ctttacaata tgaaacagca taaagccgaa caaaaggata acaaacttga aattaaaaag
     7021 atgaaagaac tattaggtat aggatttgta aaacccaatt caaaagtcac tattgcttcg
     7081 ttagcaacta ctaacaatga tgggaaaata gtaaatgggt ttgacgattc agatatagat
     7141 atattgtcaa aatcatattt ttctttgtat ggagattttg cagatttgat gggtattgat
     7201 agttacttag tcaataattt tgagatcaag ggtagcgagc tgaatgatat tgtgtatttc
     7261 gttttaatct ctctatatgc aattgatcag aataccgagt accgacaaat tgactatttg
     7321 ctagtttttt atagtttgtt atatcagttc gttttaactc ggttgtttaa aaatgctaag
     7381 gaagaattga tcctgaattc tgattatgaa atagcaaaac aaattgcaag tattagaaaa
     7441 gaaaacaaat ctgaagtaat caaattaaga aaagaattaa gtattgcgag taaagaaaac
     7501 ggtcggttag aatctttagt caaatcggca aaaaaagaag aggaactttt gaagcaagag
     7561 attaaagaat taaaaggaat cagaaaagaa cttgaacagc tgaggtttga aaataaagta
     7621 ttaaagcaat tgcaggagca agaacataga caatcattaa atggtaaaac tgaagagcct
     7681 tcactgtctg aaatgatagc ttatctaaaa cataaaaaca ttcttttagt gggaggacat
     7741 gtaaattttc aaaataaatt aactgaacta ttaccaaata ttaaaatgtt tgatgtaagc
     7801 gaaaataatg gaaagatact taaaaatttg aatacgtgtg atgcgatttt tctatataca
     7861 gattacttga atcatggtct atattatcgt gttatgagtg aaatttctaa taaagataag
     7921 atattttatt tggataatca tgtgaatatg aacttaacaa ttaaacgtat ttacgatctt
     7981 ttatcactta tataaagaga gaagtgataa ataggacaca aaatttggaa agtaggtaag
     8041 tcactatgag agaactaact ttatcttcta aggaattaga aaagaaaact gctttattaa
     8101 acgaaatatt tagtgctgat tgtataatcc aaagtttaaa agaaagttca ttttcaaaac
     8161 taacagatca ggaaaaaatt tcttatatgc taagtttaga taatctagga actaaatatg
     8221 atgaatcagc aagtagcgat aagcttttga ttgaattagt atcaagtctt agtagttttg
     8281 gaaaaatgaa aagatttaat gtgatattag aaatttttgc ttggttaaca gcattaggca
     8341 gaagtcgccc atcctctata ggtgggtgat gaatgccgtt cggtatgagg gttaccgttg
     8401 gtaactcgaa gaccgaaaag ataaatgcta taattagttt gattccaagc atgatggtgc
     8461 aattccagtg tgaaggcgct caagtgaaag atattgagtt agcgccacaa gtaaaactgt
     8521 aagacttgaa gacattcgtg acgatgcgag tgtaacaatg attatgatta gagtgaaaaa
     8581 caaactgaat ctgtcataac gttgtgtggt tagtatttcg accgacgata aaaataaatc
     8641 aaaaaaaccg taggaactac ggggatagct tggtaaataa gagaaaccgc tgttagtgaa
     8701 gaaataagct atcaagtatg ctctattccc aagaagctcc cacttcaagt gttaagaacc
     8761 gttaggttta gctaagtggt gagtagttca ctaacttgta tacacgtatt caaataaaaa
     8821 agcagttatt acatgaagga ttaagtggta atatgttaaa aagaattgca tgggataaag
     8881 ataataaaac agatattgag cttaaagaat ataaatacaa ttatttctcg agatgtatag
     8941 atagaaagtt actgtttaaa aaagaaggat tagaatttag ttttgatgaa gatgaatttg
     9001 aaaaattagt gatggactgg cgtaagaatt tactggatac ggtacaattc taaaagcaat
     9061 tgaggtcgaa attccgatac ttgaatcatg atctatatta tcgtgttatg agtgaaattt
     9121 ctaataaaga taagatattt catttggaca gtcatgtgaa tatgagctta acaattaaac
     9181 gtatttatga tcttttatat gtttataaac attaatgagg tgctaaaatt gacaacaata
     9241 actatgacaa aaaaaataga agtatatgtt gatggatcac aagaagaaag ggattccttt
     9301 tttgattttt tttggaaaaa tagtagagaa tatgtaaaag cgttgaatct ggtatataaa
     9361 cagctaatgt ttgaagagtt gataaaagat gcaattaaag aaatggatca aggttatgct
     9421 gagagagaag aaagtattca aaatcggatt gaaaagttag catatactga tccaatagat
     9481 caaaaaaaac ttgataaagc aaaagctgaa ttatctaaat tgagaaatga aaaaaataaa
     9541 gaagcgagag aaatattaac gcaagcgata gggttgaaga gtcaaacgag aacacgagat
     9601 gtagcaaaaa aattagactt tgactttgga gattttgttg attccgcaaa tatgaaagct
     9661 agtaaagatt ttggcaatga ttttatcgga attgtgaccg gacaaagaac gcctagaata
     9721 tataaaaata gaaacaaata tggattacta ccttttagag gtcgagatat taaaatccat
     9781 aaagatgata agttttatat ttatttacct aaaggcttta ggtttaaagt gaatttaggt
     9841 agcaagccaa gaaaagcaag agatgttgct tcagttttac aacacattat ggatggcgat
     9901 tacaaattaa atcaaagtaa tcttattttt gatggaagaa aattattttt taatctaaca
     9961 atttcttttg aaaaaagcta taatgaaatg gaattcaaga aaggtaatga attgatcgta
    10021 aactttgcag atttgtgtag cggtgaatgt ttaattaatg ataaatctgt aatgtctttt
    10081 ggtgatagcc aatatataag aaacttcaaa agtaaaattt tagcaatgaa atcaaaagaa
    10141 caaagccgag gagtcttttc taagggcggt catggtcgaa aaagaaaatt agatcaagat
    10201 cgatgggaag caataaagaa aagagaaagt aattttgtta aaacttataa taatcaatgt
    10261 tctgcaaaaa tcgttaaaac tgctattcgc aataaagctc aaattattcg tatcattgaa
    10321 ccagataagg cttatggcga atgggcttac tatcaattga aagaacaact agtaaacaaa
    10381 ggaaaaagat atgggataga agtcagaagt tagtaaatta aacaatcgtt gatttggcaa
    10441 cgaaatagtg agggaaaatc cactcactga agggtaaact ccgtcaagtt gtgtgaccag
    10501 acggaaggac gaatgttgtt gaggttttag aaccatataa aacagcatgt ttctcaaatt
    10561 tttaggataa gggaaattgc tagcagtttg ttttagaacc atataaaaca gcatgtttct
    10621 caaatgagta ctttaaatta attgatggcg ttcctgcttt agaaccatat aaaacaacat
    10681 ggatttaaaa caagaagtaa gtcagttctc cttttacttt agtaaggaaa aataaagtat
    10741 tctcaataaa acttaaaata agcaaacctt tgttttaata gctaatcgaa gtaaaaccca
    10801 aagccatatg aacccctgaa tcagcgaaag tttatgatga tttggattac taatagttta
    10861 ggaattagat ggtaaatcta aattaaacaa tcgttgattt ggcaacgaaa tagtgaggga
    10921 aaatccactc actgaagggt aaactccgtc aagttatgtg accagacgga aggacgaatg
    10981 ttgttgaggt tttagaacca tataaaacag catagttctc aaattgttta aaatgattgt
    11041 caagttaaaa aaatctggga tcatataaaa tagtatagtt ctcaaatatg attagaaacc
    11101 ctattaaaga gcaatattaa gccaacttac ttaaatcgtt taattaagaa caataatctc
    11161 ttttagtcag acttttagtc tgactttttt gtatttccaa aatttattct ttacaaaaac
    11221 gaacatacgt ttgtataatt gcttgtgaat gggggaataa aaatgtttga ttacagtaga
    11281 gaaccggtga atgactattt tttaatcgac atgaagtctt tctatgctag cgtggaatgt
    11341 attgaacgaa atttagaccc aatgactaca ccgttaattg tcatgagtag atcggacaac
    11401 actggttcag gtctgactct agcttcttca cctactgcaa agaaaaaata tcatattact
    11461 aatgttagta gagctactga tttaccttat ccattaccaa aagaacttca tattgttcca
    11521 ccacgaatga acttatatat aaaaaaaaat atggaagtta atcagatttt tagaaagtat
    11581 gtcgcagatg aagatttatt gatttattcg attgatgaat caattttaaa agtgacaaaa
    11641 tccttaaatt tatttactag ttcaggaaca agaagcgaga gaagaagaga attagctaaa
    11701 ataatcaaag atgagattca gaaagaaaca ggtctaatag caacagtcgg aataggagat
    11761 aacccattat tagctaaact tgcactggac aatgaagcga agagtagtaa agaatttata
    11821 gctgagtgga cttatgagac tgtacctgaa aaaatatgga aaataaacga gatgactgac
    11881 ttttggggca ttggatcacg catgaaaaaa agattgaatc atatgggaat tatgagtata
    11941 gaagatttag caaattggaa tccctacaca attaaaagtc agttaggtgt aatcggactc
    12001 cagttatatt tccataccaa tggaattgat cgtacggata ttgctattcc accagaacca
    12061 accaaagaaa agtcttatgg gaattcacaa gttctaccaa aagattatac gaggagagaa
    12121 gaagtagaac tagtagtcaa ggagatggca gagcaagtag ccattcgaat tagacaacac
    12181 aattgcaaaa ctggttgtgt acgcttagca attggtacgt caattttgga agaaaaatca
    12241 ggtttctcgc accagatgaa aataccaatt acagataata cgaaagaatt acaaaattat
    12301 tgtctttttt tattcaataa gttttatgag gggcaggaag tacgacatat aggagtaact
    12361 tatagcagat tagtatacac agattcccta caattagatt tatttagtga tccaagaaaa
    12421 aagattgctg aagaaaattt ggataggatt attgataaga ttagacaaaa atatggattt
    12481 acagctatta tacatgcttc atctatgtta gaaggtgcaa gaagtattac gagaagcact
    12541 ttaataggag gacacgcagg aggattagga ggtttgcata atgattgaat ataacgatag
    12601 aggacgttta aaatggtcgg gattttattt gtctgatcat actgaaagaa tcaatgcaga
    12661 caatgtacaa cgtgctaatc ataatttggc aaaagaacaa atgacgactg aagagattgc
    12721 gaaaatactg agaactgctg tcataaaaaa tagacccgtc tgcattcaaa aagaggaacg
    12781 aaacgctgaa ggttactatc cagatgatgt agtaggaaaa attattggat atgacgagct
    12841 tggtgtattt gtggaagaag aaaaagttca ctatgatgaa attaggaatg tttctttctc
    12901 ggaattatta aaatggagtc agatatgaac attattaaaa aatacgaatt cggttatatt
    12961 acgtatgaac agctaataga ggaattatgg ggatatggtc aacaattaat taatgaagtg
    13021 gggattgatt gcttttgttt ctatattgaa tccggagcag gataccataa gaacagatac
    13081 tatatatttc catatccacc aaaatagtct cttagatatt tttaaatttt ctccaaatac
    13141 tttcaattat tgtgaaatat ttccctttaa ttaatcaaat tttttataaa agtaatatat
    13201 aaaataaatt gcttgaagta ttatatttag atatcataat ttatggaaga aaaattaatt
    13261 aaaaaggatg agattataat ggggttactg gttccgagag ctaatactta tactatacct
    13321 ttaacgaaac gccaattaat tgctaaaaga tatcaaagga ttactagagc catcaataga
    13381 gagttttgga attctgaaag tgatactgct cacagtttat acgtaggttc ttatgggaga
    13441 ggaacggcaa ttagtactag tgatatagat ataatagttg aattaccgat ggcagaattt
    13501 gacagattca aaaattattt atcaaatgga ccgtctaagt tattacaagt tataaaaaac
    13561 gcatttcagg aaatactacc aaatagtgat attagagctg atggacaagt tgttaaaata
    13621 aatttccatg atggaatcaa atttgaaata gttccagctt ttaatgaaaa agattatttg
    13681 ggtgagtcaa aagggtttat ttatccagat tcaaacatgg gagggaactg gaaagctaca
    13741 aatcccaaaa aagagcaaga agccatgaaa ttaaagaata caaaaagtaa taatttatta
    13801 tatgctacgt gtaaacattt tcgacatgta cgagatacag aatttacgag ttatcatctt
    13861 tcaggaatag taattgacag tttcgtatat gaggctatgg gaaattggaa attcgttgaa
    13921 aataacagtg ggggtcaaaa cattagttct gtatcttatg agacagcttt attagaatac
    13981 tataactcac ataaagttat gggcggttta aatttatact ctcctggaag caatcaattt
    14041 gttaattctg atagtagtat catatgttta gaaaaagtat taaaaaaaat agctttataa
    14101 agttttatgg aggaacaaca tgggagacga aaaaaagcgc ttggaagttc aattacgtga
    14161 agcatatgga cgagtaacgt atacttacac cactcattta aagcaagccg ataatattat
    14221 ttctgacaat aaaattttaa ggtgtcttca aattggtttg tcagccctta ctactggagg
    14281 ggtacttagt accattatta ctgataatag tgagttaacc tttgttgctg gattatgttc
    14341 aacaatttct cttggattaa acttatactt taagaatttt gatcttgctg aagaagctaa
    14401 aaatcatcaa attgttgccg ataaattatg gttgatcaga gaagaatacg taagcttact
    14461 aacagattta aatcgtttaa gtgttgaaga tattgtgaaa aaaagagatc aattaatgaa
    14521 caaaactcat gaagcatata aaaatgcccc taaaacaaat agtaaaagct atgaatcagc
    14581 tcagaaagca ttaaaatctg aagaagagca attttttaca gaagaggaat tggataagat
    14641 gttaccagag catcttagaa aaaagagttc taaatattga actctttttt tatgcttaaa
    14701 attttcttgt aatttttcta ttcaatcaat aaataatcta tatttaagaa gaaatatgat
    14761 gatagaaaca tctcctaaag ccaccgcaag ccgtcctagc cattgcccag tccgacatcg
    14821 ctagattagt gcatctctcc aaaaaagttt tctaaagcca ccgcaagccg tcctagccat
    14881 tgcctagtcc gacatcgcta gattagtgca tctctccata aaagttttct aaagccaccg
    14941 caagccgttc taagcatagc ttagcccgac attgctagat atgctcatct caccatgaac
    15001 gtttcctaaa gccaccgcaa accgtcctag ccatcgccta gtgcctagtc cgattttgct
    15061 tgatcggttc catttctgtt tatttagtgg gtcaacaccg taatcttaaa tagccatcgc
    15121 ctatttaaga ttactaggtc tgctttgaag gtaaaaagtc tttcattctt caagactttt
    15181 aggctttcaa gctacgcctg aaagcattga aattcatcgc tctttatttg gttttgccat
    15241 ttataattcc ttacgcccat tatctttttc gcctgtcata ccttgtcaga agtgtttaga
    15301 gcttatctca tctttggatt aatacaagtg gcgtaaattt ttttctaaac gcaagcgtta
    15361 cgaaaataat ttacttaaac acttgtatta atccggcaga taagaacgca ttctaatcac
    15421 tcccgacaag gcaagacagg cgaaaaagat aaataaatga acgaaaggaa gaaacataaa
    15481 atgcaaaacc aaatagcgat gaagaaaaaa ccacctccct ctaaaacaat ccaaacaaaa
    15541 aagaattttg aaaaaccaaa aatcaaaaac agaaagaagc gttcaacatg agagatagaa
    15601 ttttagaagt taatcaagaa atggtaaaca agttaacaaa tatcagtggg aactatgaaa
    15661 agtacgatgg tactttactt gataattata tttttcacga tacacaaaat atcagaattg
    15721 gcagaagtaa accgagagcg ttcattctca tcaaagagaa atatttgaat gaatggaata
    15781 gcacctatga aatggttatg actgataact ttgaaaaggt attggatttc agaaatgctt
    15841 tgttgggttc tgatatggga aatagcagtc ttgaatctat tgaagttgaa aacaagaccg
    15901 agaatgaagg tgaaggattg attaagaatg tcctgaaaat cgaacaaaaa tatatcagtg
    15961 aagatagaag tttttataga gtcacaagct cggttggtct agcaaacttt gctactaact
    16021 taattggaaa caatgctagt gaatctttgc tagtgatgtg tctgaataca aagaatgagg
    16081 tcattgctta tagcgaagtt ttcaaaggtg gaattaatca atcagtagcg ataccaagag
    16141 agatttttca actagctttg ctaaacaatt cagcaaaaat cgcagtatca cataatcatc
    16201 cgagcggata tgaatttcca agtgaaaatg acaaaagttt tactacgaat ttgaaaaacg
    16261 caggaaaaac aattggtatt gaattgttag accatatcat cgtaacaagt aaaaacacaa
    16321 gctattactc atttcaagaa aatggttctt tataaaaatt agagaaaaga ggaaaacaag
    16381 atgggcg
//
LOCUS       DACGLI010000062        16334 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.064, whole genome shotgun sequence.
ACCESSION   DACGLI010000062 DACGLI010000000
VERSION     DACGLI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.064"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(119..775)
                     /locus_tag="IXT22_002336"
     CDS             complement(119..775)
                     /locus_tag="IXT22_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4863668.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            968..1246
                     /locus_tag="IXT22_002337"
     CDS             968..1246
                     /locus_tag="IXT22_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863669.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            1265..2473
                     /locus_tag="IXT22_002338"
     CDS             1265..2473
                     /locus_tag="IXT22_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863670.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(2621..2986)
                     /locus_tag="IXT22_002339"
     CDS             complement(2621..2986)
                     /locus_tag="IXT22_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAQ4863671.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(3133..3906)
                     /locus_tag="IXT22_002340"
     CDS             complement(3133..3906)
                     /locus_tag="IXT22_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4863672.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(4080..4940)
                     /locus_tag="IXT22_002341"
     CDS             complement(4080..4940)
                     /locus_tag="IXT22_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAQ4863673.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(4940..6358)
                     /locus_tag="IXT22_002342"
     CDS             complement(4940..6358)
                     /locus_tag="IXT22_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4863674.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(6415..6864)
                     /locus_tag="IXT22_002343"
     CDS             complement(6415..6864)
                     /locus_tag="IXT22_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4863675.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(7309..7572)
                     /locus_tag="IXT22_002344"
     CDS             complement(7309..7572)
                     /locus_tag="IXT22_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAQ4863676.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(7671..8966)
                     /locus_tag="IXT22_002345"
     CDS             complement(7671..8966)
                     /locus_tag="IXT22_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAQ4863677.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(8963..10234)
                     /locus_tag="IXT22_002346"
     CDS             complement(8963..10234)
                     /locus_tag="IXT22_002346"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4863678.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLITTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(10399..11268)
                     /locus_tag="IXT22_002347"
     CDS             complement(10399..11268)
                     /locus_tag="IXT22_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAQ4863679.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(11560..13170)
                     /locus_tag="IXT22_002348"
     CDS             complement(11560..13170)
                     /locus_tag="IXT22_002348"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAQ4863680.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(14363..15703)
                     /gene="glnA"
                     /locus_tag="IXT22_002349"
     CDS             complement(14363..15703)
                     /gene="glnA"
                     /locus_tag="IXT22_002349"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAQ4863681.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(15731..16123)
                     /locus_tag="IXT22_002350"
     CDS             complement(15731..16123)
                     /locus_tag="IXT22_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4863682.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4661 a         3462 c         2777 g         5434 t
ORIGIN      
        1 tgttcaatca gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt
       61 ttccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttgttcatc
      121 aaaagataat attgtcttct aacaagtcca tattcaaaat aacgatatga tggtctttaa
      181 cggtgataat accatctttt ttcagttgtt ttaaaattct gtttacactg ctagcagttg
      241 agatgccaca aaatttggcg atttcttcat tcgtgatcga aaaatcgatc agcatccctt
      301 cttctgtccg cacaccgaat aaatcatata attcgtaaag ttgcgtacaa acagctccca
      361 gctttccgtt taatagcatt tgctgcattt ttttcatcga ataaagcaga cgatagcggt
      421 aatactcttt tacatagtgt tgtagctttg ggtcttggtt gatattttgc caaaagcgca
      481 cacgattgat tcgataaaac tctgcatatt ctgattcaac tcgaatatta tacggcgaat
      541 cgatgaattg tgaatattcg tcttttaaaa gagagacgat ttcaagatct ttgatatagc
      601 gaaggttaaa ttctctccca tcatttgaaa taacacttgc ttttaccgtt ccctctttca
      661 agatatacgt atgggaatct tccatccctt cgaatgtcaa atatttatga tatcctttgc
      721 gtataatcgg aaaatcattt ttatccaaat attcctttaa gactctacta tccaatgatg
      781 ctcccccatc caaactttca tctaaaaaga tcatacagta ctttaaaact ttttaaagtc
      841 caaaggtatt ttactaatga tattaacatt tgttaagtac ctttttccat cacttatgcg
      901 atttttttcc ttttttttat tcgttatact gcagaagtaa aattttttaa gaatagaggg
      961 aaaaaacatg aattactgga tgaacacaat cattaatcga ttagaaacag catatcaaac
     1021 aagatttgat atgaaagctt ctttagtctt tttaaatgat gcgtatcaaa actcgatcga
     1081 attgatcaaa gcagtggatg agaatccaac aaacgaatgc gaagaatttt taaatctgtt
     1141 tatgtctaca agagatttat ttattcgcca acttgttgat cgctatccat ccaattatca
     1201 cgatgtagaa gttcaaatac aaaaattaaa agcatattca gcttaagggg aatgtataac
     1261 atacatggaa aagaaattat ttaataaata ttttattgga atcacattga tcaattttat
     1321 tgtctacctg atttattatc tgttgatggt catcatggca gtcattgcgc aagacacctt
     1381 acacgccagc ttgagccaag caggttttgc ttctgggatc tatatcatcg gaacattgct
     1441 ggcacgctta ttcatgggga aacagttaga actatttggt cggaagttta ccttaagagg
     1501 cggcgcgatc ttctatctcc tttcaacatt agcatatctt tatacgccaa ctatcggggc
     1561 attgtattta gttcgattct tgaatggatt cggctacggt acagtttcta cagctacaaa
     1621 tgctatcgtt actgcatata tccctgcatc taaaaaaggg gaaggcatca attattatgg
     1681 attaagtact agtttagctg ccgctgttgg gccattttta ggaatgattt tgctgaatat
     1741 gactgatttt cgtttcatta tctggttttc aattgtactg gtcttctttg ttacgattgc
     1801 ctgccttgtc tttcctgtaa aaaatattcc attatctgaa gaacaaaaaa tatctcttcg
     1861 ctcatggaat atcaatagtt ttattgaaaa gaaagcactt ttcattacag gaattgcctt
     1921 tttgatgggt ctttcttatt caagtgtttt atcattttta tcttcttata caaaagtaat
     1981 ccacttagtt gctgctgggt catttttctt cgtcgtatat gctttggtca tcacatttac
     2041 acgtccattg actggaagga ttttcgatgt caaaggagaa caatacgtga tgtatcctag
     2101 ctatttattc ttaacagcag gattattttt actgagtgta acgacgaata gtgtgacatt
     2161 gcttatctct ggagcattag tcggcctagg ttatggtacg tttatgtcaa atggacaggc
     2221 tgtttgttta aaaatcgtcc gcgaacatcg aatcagtatt gctttatcta cctactttat
     2281 tggtttagac ctaggcttag gcgttggtcc ttatttgatg gggatgctaa aatctcttac
     2341 ttcatttaga ggattgtatg tgattgccgg agtcattcca ttgatatgta cagcactcta
     2401 tcttgttaat ggccgaaaac atagtcatga agcagagggc gaattgattg aatcattgaa
     2461 aaatgaaatt tgatcttgat gaatagataa aaaaaaccgt tcagatctga aaataatctg
     2521 agcggttttt tgagtaaaaa tagtttatga ttattcttaa ttaaacatct atttattttt
     2581 aaagctttca tttatcgata agaatagttt aactgttgat ttattccatt ttccgttcat
     2641 ctggtacgat gccttgactt agcaaccact tgtggaagaa ccattctgcc acaccgatca
     2701 atagagcagg aatcaatact ttcatccaaa tatcgactgt atcattcata aaatatagat
     2761 agagccacaa gataactgca gctgaaccag catctgcgat cgtcgctgcg atgttcccta
     2821 ctttacgtaa gatcaacaga tcccctagca catagatcat gactacaata attaccccaa
     2881 caatcgttga atccataaag ctaacaccgt ataaacctgt cagcacgacc cacagaatcg
     2941 cccagatcat gattgccttc actaccaacg ccttcacatg tttcattttc tgcactcctt
     3001 tctcctggat aaaaaagtaa gattatctaa caagataacc ttttcattat tataccatcg
     3061 gctgagagaa gcgagcaaag ataaggtcct atctaaaaat gaggaagcca cttagaacat
     3121 tcacgtaata atttatccgt acagacattc gatatggtgt tcctttactt tcgcatactg
     3181 ttcttttgtc agttctttac ttgtcaccag ataatcgatt tcatgaaaag caatggcttg
     3241 atgcatgaat ttatgtgcaa ttttttgctg tgtaactaaa acggcaagcc ggtctgattg
     3301 ttttctaaaa gcttttttga ccattgcctc tccttcatga gtttctgtta ctccttggct
     3361 gaaatctagc ccgcgacaac tcattatcgc taaatccgca taatatgaca atgcatcgtt
     3421 ataggctttt gaaccgttga ttgttgctcg tttcggaaca attgcccctc ccaatacaga
     3481 tacttttgcc gttgtatatt cactcaacat agcagctgtg acgatgccat tcgtaatgat
     3541 ctgcaaacca tcaaatcttg ctaggtttct gactaagtgt aaagaggttg tactggaatc
     3601 caagaataag accatatcat ctcgaatcaa agaagaagct gtatctgcaa tcttacgttt
     3661 ttctgtttct tcttctaatt tggtgatctt catcaggtaa ggcacgtcaa tttttcgatt
     3721 gtcaataagc atggcgccac cgcgaactct acggatcaat ccactttttt ccagaaaaac
     3781 aaggtcacgt ttaatcgtgg cttcgctata atttactaac tcgatcaaat cggtgactct
     3841 tgcaaattgg ttgtttttta gataattcac aatctcctgc tgtctattct ccacttcatt
     3901 caacataaaa tcaccccatt tactttatat agtaacagga aaaaagaggt tgtgacagaa
     3961 gtgattggct tcgagaaata agaagaaatt tttcgaaaaa actacttctg aacatcgtgt
     4021 gtggttaaga gggtatgaca agactattgt cataccctct tgaccacaca tttttatttt
     4081 tagtataaac tagccttgcc tactgtgttc aaaatttcca ttttatgttt gaccacttct
     4141 tgtacctttt tattagctgc tggataaatt gcattcggct cgtacatcga tggattttca
     4201 ctcaatattt ctctcaaagc attgaaaaag acgcttttaa gatctgagct caaattcact
     4261 ttggcaactc cgtattttac tgcttcgctg acttctgcgt ccggattacc tgaaccgcca
     4321 tgtaaaacaa atggaagatc gatttgttgg ttcaattctt tcagtaagtc gatatttaat
     4381 tttggagttc tgtttttcgg atacaagcca tgcgctgttc caattgctac agcaagtgta
     4441 tcgattcctg tttctttcac aaaaatcttc gcttgatcag gatctgtata aatgattgtt
     4501 tcagcacctc cttcagcaga accattattc ccaatcgttc caagctcagc ctccactgag
     4561 acatttaccg catgagctaa cgcaaccact tttttcgtaa tctgtacatt gtcgtcgaat
     4621 gatttcaaag acgcatcgat catcacggaa gaatagccgt ttcgaatcgc ccgtaagaca
     4681 tcttctatcg taccgccatg atccaagtgg ataacgatcg gcagtttact tgtataagca
     4741 taggctctta ctgccgcaac aaactcatca ctcaaatagg cgatttcatc aggatgaatt
     4801 tctaagatta ctggtgcttc taatctctct gcttcttcga tgattgcttt catcatatca
     4861 tagctgcaaa tattgaaggc tggtactgca aattgattct ctttagccac tttcaataac
     4921 tctttcattg tatataacat tacgcttcca cctcatttgt tagattttca tttttcgtcc
     4981 acttgtcttg ttttttctct ttcactgttt ttttcaatag tccaagcata aaggctgtag
     5041 tgactgtacc tgatgcaatt gccaagacat acataggtaa attgttcata acatttggaa
     5101 ttagcatcac ccaaatccct ccatgaggtg ccattgaagt aactcctact gccatggaaa
     5161 tccctgcagc gactgctgaa cctgtcatca aactaggtat cacgcggatc gggtcagata
     5221 ccgcaaacgg tatagcacct tctgtaatat acgaagcgcc taaaatccag catgattgac
     5281 ctgaagtccg ttcttctttg gtaaatttat gtttgaataa taaagtggct aaagcaatac
     5341 ctaggggagg tgtcattcct gcagccatac aagcagcaat cggtgcattt actccagctg
     5401 acatcaaacc gatcgagaaa gtcgaagtcg atttattgat cggcccaccc atatcagctg
     5461 ccatcatgat cccgataagt aatccgaaca atagcccgga tgtatttccc aagctattca
     5521 gccaatttgt caaagcatcc aacacccatg tgatcggttg ttcaatcaca aataccatca
     5581 aaagcccaat aattaagatc gataaaaagg ggacgacaat cagctgataa atagcagaaa
     5641 attctttttt tacgctaatt ttatttgcca gaaaatcaca gatataccct gctagcacgc
     5701 caccaatcat tccgccaaga aaacctgaac cacctgtaga ggccagtaat ccggcaacaa
     5761 ttcctggggc aaaacctgct tttccagcaa tcgatgtagc aatccccgcg cctaacgcag
     5821 gaaccatcat ggcaaacgct gtatctcctc cgatccttga aaatgcagct gctaacacat
     5881 tatagtctgc tgagttggga tcagccgctg taatcccaaa ggcaaaactc agtgcgatga
     5941 tgattccgcc tgcgatcaca aatggaagca tgtaattcac accattcatg aaatgattat
     6001 agattgtcgg ctttttctca tttgcagctg gttctttttc attagacaca acgaatacgc
     6061 caatatctct caatgcttcg tctattacta cttgcggttc tttgattgct cggcttgtag
     6121 agacacgctt tacttttttc ccggcaaatc ggtccaattc gatttcttta tctactgcaa
     6181 gaatgattgc atctgcctct ttgatttctt gttcagataa ctgattttct gtttttacac
     6241 cttgtgtttc gaattttgct tgatggttta gatttcttgc tgttacttct aatttttctg
     6301 ccgacatata agtatgagca attccagtcg ggcaagcagt tacaccaacg attttcatga
     6361 ttattttcct cctttttctt cactatcgat actcggacaa agactctact attttcattc
     6421 ttgactaatc tgtctgatga tatctgctgg cgtagtggct tcttttattc cctttctaaa
     6481 atctgcattc atcaatcgtc tggagagtgt gctgagaatc tctagatgca tatctgctga
     6541 tttttcagga actacgatgg caaaaatata ttcaattggc atttcatcta tcccgctata
     6601 gtccgttaat ttggctgtat gaaaaaaaca cagtgctggt tttgtcacat atttgctttt
     6661 tgcatgggga atcccaaatc catcttctat tcctgtggag atctcctcct ctcgtttgaa
     6721 tagtgcctta acgacttttt gaacatttct taccttattt gtttttttca acacatcccc
     6781 tattcgctca aataatgatc cttttgaatc tatcgatgga tcgaaaacaa tcagttcttc
     6841 tgcgatcaat tgatcaaacc tcataaaaaa cctctccccc acaaaaaatg ttaacgtttt
     6901 cttggaactg aggtcagtat agcatcgcta gctgtaccgt tcaatattat gaatgaacag
     6961 aggaaaaaga cccatcatcc gcgtgtataa gtcattaaaa tgaacgatct agctcacaaa
     7021 caatcgcaag tctataacaa aacaaaaagc cttccttgaa aggaaagctt agcttctaat
     7081 tttaggtaaa tggtttttta cttcgaaata acccctcttc atttcgttaa tataaggtgt
     7141 ttttatcaag tggataatta aaactatata ctagtttttc attgttttgt gcattatgat
     7201 cctacgactt tttcagcatc aaacgaagtt ttaaattggc aaaaaacata aaaaaacaga
     7261 ctatccctat cagatagtct gctaaacgtt gagttatcag cgtttttatt attccgcagc
     7321 gtttgcgtct ttgagaccgt attttttgtt gaaacggtcc acacgtccgt ctgcttgtgt
     7381 gaatttttga cgtccagtgt agaatggatg tgagtcagaa gttacttcga cacggatgac
     7441 tgggtatgta ttaccgtctt cccattcaac tgtttcttgt gaagtttttg ttgaacctga
     7501 caagaatttg aaaccagttg ttgaatccat gaatactact gggtggtaat ctggatggat
     7561 gttttctttc atgatttttt cgctcctttg ccctgctcca tttgctgaac cagagttgat
     7621 ttgtcgattt acaacattaa catcttaaca tgtttcagtc aaggttgcaa ttatcttttc
     7681 agatttctgg tcggattttt tttaccaaag gagacatctt gaaattcttt gaaaaattgc
     7741 tgattgtttt ttgttttacg caaaaagcgg atcagttgtt ccgtatattc taatgaatct
     7801 ccagtcatat tttttcgaag tttccaaatt tcttctaatt cttcacttgg catcaataat
     7861 tcttcttttc gggtacctga ttttttgata tcgatggctg ggaagatccg acgttcagat
     7921 aattcacgtg aaagttgtaa ttctagattt ccagttcctt tgaattcttc atagatcacg
     7981 tcatccatac ggcttcctgt atcgactaaa gcggtcgcta aaatcgtcaa actgccacct
     8041 tcttcgatgt ttcttgctgc cccgaaaaat ttcttaggtt tatacaatgc ggctgggtca
     8101 atcccgccac tcaatgtacg tccgcttggt ggaacgacta agttataggc ccgagcaagt
     8161 ctagtaatac tatccatcaa gataacgaca tctcgtttat cttcgactaa acgcattgcg
     8221 cgttccaata ctaattcaga aactcgagta tggttttgcg gctgcagatc aaatgtagaa
     8281 gataccacgt cgcctttcac gcttcgttct agatccgtta cttcttccgg tcgttcatca
     8341 atcagtagaa cgattaattc tacttccgga tagttttcgg tgataccatt tgcgatttct
     8401 tttaatacag aagttttccc tgcttttggc ggtgcgacga tcaatccacg ctgaccaaaa
     8461 ccgattggag aaaagatatc gatcattcgg gtagatagtc tttgcggtgt tgtttccagt
     8521 tgaagctgtc tttgcggata aagaggtgtt aaggctggaa aatgcggacg ttcttttgct
     8581 tcttccggat cttttccatt aacgctttcc acgtgcatca aaccataata acgttccgat
     8641 tctttaggtg gacgggcttt tcctgccact ttgtccccat ttctcaaact gaatcgtctg
     8701 atttgtgagg cagaaatata gatatcttct gcacttggtc cataattgat tggccgtaaa
     8761 aaaccgtaac catcttgacc aacgatatcc aatattcctt ccatataata aaatccttgt
     8821 ttctctgctt gtgcacgaat cacagctaga gataattcct ttttattcat cttactgtaa
     8881 taaggaattt taaattcttt ggcataacta taaacttctt ttaacgtttt gttctctagt
     8941 tctgccattg tcaaataatc gctcattcag ctcccacttc ctctatcatt tcaattgatg
     9001 cccctaaggc tgttagtttc tcgataatat gatcataacc gcgtaagata taatctacat
     9061 tgtaaatcgt cgttgtccct tctgccaata gtccagcaat cactaaacaa gcacctgccc
     9121 gaagatcaga agccacgact tctgtgccgt gaagtttatt tggaccattc acgatgatca
     9181 tatttccttc cacggtaata tcagcgccca ttcgtgctag ttccggcaca tggttcacac
     9241 gtttcgcata gatcgtatcg atgatttctg aagtgcctgt agtaatcaat agtaacgcag
     9301 taagtggctg ctgcagatct gtggcaaatc ctggataagg ataggtcatg atgtttgcgg
     9361 gttttaattc tttcgagggg taaacttcga tttcatcttc gctgattttc atatggacac
     9421 caatttcctg caattttgct ataaagcttt ccaaatgttc aaagatcaca tttttcactt
     9481 tgataccatt tcctactgca gctgctaatg ctagataggt tcctgcttcg atgcggtcag
     9541 gaatcatgaa atgccgacag ccatgtaatg tttcgactcc ttcgatacgg atcacatctg
     9601 tacccgctcc tcgaactttt gcccccatat tattcagtaa agttgccaca tctatgattt
     9661 ccggttctcg tgcagcgttt tcaattactg tctgtccttt tgcttttaca gcagctaaca
     9721 tcacattgat cgttgctccg actgaaacca cgtccatgaa aatccgattg ccacgcaatc
     9781 ctttattttc tgtccgtaaa tacatggcac catgttcatt tgtcacttca gcacctagag
     9841 cttcaaatcc tttgacgtgt aggtcaatcg gtctagggcc taaataacag ccacctggca
     9901 ggcctactac cgcttcgcca aatttaccaa gcagtgttcc cataaaataa taagaagcac
     9961 gcaaactatt gatttttccg tgcggcatcg gaatcgatac gacttctcga ggatcgattt
    10021 ctagtatgtt gttggaaaaa tggacagttg cgcccatgat ctctaaaatt tcaattaatg
    10081 aatgaacatc ttgtatgtcc ggcacacctt ccaagatcac tggggaatca gctaagattg
    10141 cagctggaat caatgcgact gcactatttt ttgcaccgct gatcgttact tcaccagcta
    10201 aaggtcggtt tcctttgatt acgatttttt tcatctgttt ccaccttgtt tattaatctt
    10261 ttttcatgga tatgcttgta ttttatcata gataaaaaaa agaaacgagc atggtctgcc
    10321 gttttaagta aaaaagaatg gagagcgact tcaaaagtcg ttctccattc ctatatatcg
    10381 tatctgttat gtggatgctt acgctttgtt agctgaaccg aaccagtcga tatgagattt
    10441 agcatcttca acgattgctg ctttacctgg agctaataat ttacgagggt cgaatccttt
    10501 accttcttta tctttaccag cttcgatata tttacgagta gctgcagcaa atgataattg
    10561 gaattcagtg ttaacattta cttttgagat acccattgag atagcttttt cgatttgatc
    10621 ttgaggaata cctgatccgc catgtaatac taaaggcatg tctggaccta cagcatcagc
    10681 aattgcttgt aagtggtcaa aagctaatcc tttccagttt tctggatatt gaccatggat
    10741 gttaccgata ccgcaagcta agtagtcgat acctgtagca accatttgtt tgcattcttc
    10801 aatatcagct aattcgccgt taccgatgat tccgtcttct tctccgccga ttgaaccaac
    10861 ttcacattca actgagatac cttttgcatg tgctttttca acaacgtctt tagctaattt
    10921 caagttttct tcaaatggta gatgtgaacc atcgaacatt actgaagtat agcctaattc
    10981 gatacattcc aaagcagctt cgtaatcacc atggtctaag tggatagcaa ctggaacagt
    11041 gatgttcatt gcttcaacta aatcagtgat taaatcttta cagattttgt aaccacccat
    11101 gtatttagct gcacccattg atgtttggat aagtactggt gcttgttttg cttcagccgc
    11161 ttcaaggatt gcttgagtcc attccaagtt gtttgtgttg aatccgccga cagcgtaacc
    11221 gcctttacga gcagctttta aaaattcagc tcctgatact actggcataa taaaattcct
    11281 cctaagtttt gtaaaactaa atttgttaag acaattctta accaacgacc ctattttacc
    11341 aaacatttcg gtagttttct actaaaatca atgaaaatga aaattttcaa gaagtttttt
    11401 gcaaaaaata aaatatccaa tagcgcttta atcgaaaaaa gtcttttgct ttctatcttt
    11461 tttcctacaa ataataacaa atcagaaaaa gagaaaagtg acaagaaaat tgcttatccc
    11521 cttctcttgc tacttttctc tttctatcaa gttcaaaaat tattttgttt cgtgatctgc
    11581 taatgatgct ccgacaaatg ctttgattaa tttttgcggg cgatttggac gagaaatcaa
    11641 ttctgggtgg aattggcatc ccacaaagaa ttttttctct ggcagctcta cgatttctac
    11701 taaacggtta tctggtgaga cacctgaaaa gactagccct tgttcttcaa acaattgacg
    11761 atatttgtta ttgaactcat agcggtgacg gtgacgttct tgcacaacat cggctccatc
    11821 atatgcttca gccgtcttcg ttcctttttt gattttacat gggtataatc caaggcgtaa
    11881 agttccaccc aaattctcga tgttttcctg atcagccatt aaatcaataa tattgtttgc
    11941 tgtatctgga ttcgtttcag ctgatgacgc atcttctaat ccaacgacgt tacgtgcaaa
    12001 ttcgacacaa gccatctgca taccaagaca aatacctaaa aacggaacgt cattttcgcg
    12061 agcataacga atcgcttcga ttttcccttc tactccgcga tcaccaaatc caccaggaac
    12121 caagattcca tctgcgtctt tcaaacgttc ttctacattt tctctcgtta attcttgtgc
    12181 tttgatccaa tcgatctcga tgtctgaatt ataggcgaaa ccagaatgtt tcaatgcttc
    12241 aactactgag atatatgcat ctggtaactc gacatattta ccgacaagcg caatccgtac
    12301 ttttttcttc aagttcaaga cacgttcttc taattctttc cattctgtca tgtctgcttc
    12361 tggtgtatct agttttaaat ggtcgcaaac aatttgatcc attccttgtg cttgtaaaac
    12421 taatgggatg gagtaaagtg tatctacatc tggcgactcg ataactgctt ctggttcgac
    12481 atcacaaaat tgtgccaatt tgtttttcac gctttgagaa acaggttgct ctgtacgtac
    12541 caccaaaata ttcggttgga tacctaaacc acgtagctct tttacactgt gctgcgttgg
    12601 tttagttttc atttctccag cagctttcaa gtaaggaatc aatgttgtat ggatatacat
    12661 aacattatct gtaccgacat ctgctttcat ttgacgaagt gcttcaagga atggcaaaga
    12721 ttctatatcc cctactgttc cccctacttc tgtaatgatc acatctgaat cagtcatttt
    12781 agctgctcgc atgatttttt ctttgatctc atttgtaata tgaggaataa cttgaacagt
    12841 tgctcccaag tattcgccct tacgttcttt acgcaaaact tcagaataga tttttcctgt
    12901 cgtcacgttg gagtatttgt tcaaattgat gtcaataaaa cgttcgtagt ggcccagatc
    12961 caaatctgtt tcagcaccat catctgttac gaatacttct ccgtgctgat atgggctcat
    13021 cgtccccgga tccacgttga tgtatggatc aaatttttgg atagttactt ttaagccgcg
    13081 gtttttcaat aagcgtccta aagaagctgc aacaatccct tttccgattg atgaaacgac
    13141 accgccggtc acaaaaatat attttgtcat aagttcaaaa actccttttt aatttatgtg
    13201 caggaaaagt ctcagacaat aaacaaagct ccctattctt caataagaat agggagccga
    13261 aatttctgta aacttctgac cctctaaaag ggtgcccaag gtgtataata caagctgact
    13321 aagggaaagt caagtactca aatgaatact atccgcttac aattttttct ttttcgatat
    13381 cctttgagaa attatttctt aagtccttta tgagtgcaaa aaaaatttaa cccacataat
    13441 aagcttgata taaacatagc taacgttaaa cctaagcaaa tcagaaaatc gttactgaaa
    13501 aattttaagt gaaataatag ataaaaaaat aaaacaaaca ttatgataga taatatccca
    13561 cctaacaaag aactactttt tcctacttgc agcaacagtt tatatagctt atcgtagaaa
    13621 caatcttttt ctttcaccct tatttacctc ctttacgtaa aaaacgtagt ccacagttct
    13681 cggatttttg gcatatcttt tctattaaat aatatcaaaa acaaaacaat tccactaatt
    13741 ttttcaaaga tgaccttttt ttcaacaaaa gtgccttgta gggattcatt gaaggtaacg
    13801 aatcacataa gtaaaaaata aggagatgcg acaaaagtcg tgcctcctta tttctaaata
    13861 aacggtgttc tcctgccaac tcctcggtca caagtcacaa tatccatcaa acatgagaag
    13921 ctgtttttga aattatttct tgtgattcgg agttaaatgg taggctcaca acctctggat
    13981 aaacggtatt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa
    14041 gccattttca caaaattttt cttaatactc gaaactaaac gtctttttca aaacctcttg
    14101 gtaaacggtg ttcaaaagct tgcatctgcg gtaataagtt cagccaattc aaaaacaaga
    14161 aaagctgttt ttgcttggct attcttatta cttgttgcag ggcagctttt tcacaacctc
    14221 tccactaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
    14281 gaggaactat ttttccgtta gtttctctaa tactcaggtc aaaacgctga tttcacagcc
    14341 tctaattcac ggtattcctg ttttaataaa gttctagata ttgttctctt tcccactcgg
    14401 aaacagtttg tctgaatgcc gcccattcga gacgttttgc ttcaacaaaa tttgagaaga
    14461 tatgttgtcc taatgcgtca atcattacat tatccttacg caattctttg atagcattat
    14521 ggatagttga aggtaagtcc tggatatgtg cagcttctct ttcttcctca tccattacat
    14581 aaatgttacg gtcaacagct gctggcggtg tgatctgatt acggataccg tctagtcctg
    14641 cttgcaacaa tactgccatt gccaagtatg ggtttgcaga tggatcaact gaccgcaatt
    14701 ccaaacgtgt ggataaaccg cgagattctg gtacacgtac taatggcgaa cgattacggc
    14761 cactccatgc gacataaaca ggcgcttcat aacctggaac gagacgttta taagaattga
    14821 ctgttggatt gcaaacggct gtgtaggcac gagcatgttt cagcaaacca cctaagaaat
    14881 gataagctgt ttcacttagt tccaattcac cgtctttatc atagaaaaca tttccttcat
    14941 cattgaacaa agacatattg caatgcatac cagaaccatt gatcccaaat aacggtttcg
    15001 gcatgaaagt cgcgtgaagt ccatgcttgc gtgcaatcgt tttgacaacg agcttgaagg
    15061 tttggatatt atcacaagca tctaccacat ctgcatattt aaagtcaatt tcatgctgtc
    15121 ctggcgctac ttcatgatgt gaagcttcca cttcaaagcc tagactttct aattccaaca
    15181 cgatgtcacg gcggcaattt tcacctaaat ctgttggtgc aaaatcaaaa taaccacctt
    15241 tatcattcaa ggtcgttgtg atcccaccgt cttcgtctaa tttaaataag aagaattctg
    15301 gttcaggtcc taaattgaaa gaggtaaaac caaggtcgcg catatctttc aatgctcgtt
    15361 tcaaattccc gcgaggatcg ccggcaaatg gtgtcccatc cggattatag atatcacaaa
    15421 ttaaacgagc aacttttcca tgagcacttt cccacgggaa gatcatccaa gtggagagat
    15481 ctggatacaa atacatatcg ctttcttcaa ttcgaacaaa tccttcaatc gaagaaccgt
    15541 caaacatcat tttattttct aatactttgt cgatctggct cactggaact tctacatttt
    15601 tgatcgtacc taagatgtct gtgaacatca atcgtaaaaa tcgtacgttt tcttcctcaa
    15661 tgattcgttt gatttcttca cctgttatct gtttctttac catggtatcc ctcttccttt
    15721 tttaatttat tcagtcaaag aattgtcttt gcaatccttg cgactgataa tgacctgttt
    15781 tgcttaaccc accttgcgcc aaaatctcat cacgaaaaat ttgtcgaacg tcatgatctg
    15841 tcaacggctt cttgtttttt gcttcttgtt ttttcgcctg tgccatttcg tatacacgtt
    15901 tgatcccagc catattcaat ccctctgaaa gatagtcttt aatctcaagc aacatatcaa
    15961 tatcattcag cgaatacata cgtcggtttc cttcgcttcg ttccggatga actaaatctt
    16021 gttcttcata atagcgaatt tgccgagcag acaaatcagt cagcttcata actgtaccaa
    16081 ttggaaatac ggacatagat cggcgcaatt ccttttctcc catcagacgt cccctttcgt
    16141 tttataagtt ggctaaagtg taccaattaa aaaaaatatt gtcaactgca tatgttaggt
    16201 tttctaacat gagatctcta ttttttataa aataacaaaa aaataagaac acaaaaaagg
    16261 tatctagttg attttcgtac cagatacctt ttatttttta ttatactgta ctatccttta
    16321 ttagtgtttt tatt
//
LOCUS       DACGLI010000063        15919 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.065, whole genome shotgun sequence.
ACCESSION   DACGLI010000063 DACGLI010000000
VERSION     DACGLI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.065"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(71..541)
                     /locus_tag="IXT22_002351"
     CDS             complement(71..541)
                     /locus_tag="IXT22_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAQ4863683.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(700..1158)
                     /locus_tag="IXT22_002352"
     CDS             complement(700..1158)
                     /locus_tag="IXT22_002352"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAQ4863684.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1329..2474)
                     /locus_tag="IXT22_002353"
     CDS             complement(1329..2474)
                     /locus_tag="IXT22_002353"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAQ4863685.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2487..3404)
                     /locus_tag="IXT22_002354"
     CDS             complement(2487..3404)
                     /locus_tag="IXT22_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAQ4863686.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3832..4395
                     /gene="efp"
                     /locus_tag="IXT22_002355"
     CDS             3832..4395
                     /gene="efp"
                     /locus_tag="IXT22_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAQ4863687.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4881..6140
                     /gene="lysA"
                     /locus_tag="IXT22_002356"
     CDS             4881..6140
                     /gene="lysA"
                     /locus_tag="IXT22_002356"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAQ4863688.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6127..6927
                     /gene="dapF"
                     /locus_tag="IXT22_002357"
     CDS             6127..6927
                     /gene="dapF"
                     /locus_tag="IXT22_002357"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAQ4863689.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6930..7811
                     /locus_tag="IXT22_002358"
     CDS             6930..7811
                     /locus_tag="IXT22_002358"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAQ4863690.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7808..8524
                     /locus_tag="IXT22_002359"
     CDS             7808..8524
                     /locus_tag="IXT22_002359"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAQ4863691.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8530..9225
                     /gene="dapD"
                     /locus_tag="IXT22_002360"
     CDS             8530..9225
                     /gene="dapD"
                     /locus_tag="IXT22_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAQ4863692.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9241..10242
                     /locus_tag="IXT22_002361"
     CDS             9241..10242
                     /locus_tag="IXT22_002361"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAQ4863693.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10239..11600
                     /locus_tag="IXT22_002362"
     CDS             10239..11600
                     /locus_tag="IXT22_002362"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAQ4863694.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11560..12711
                     /locus_tag="IXT22_002363"
     CDS             11560..12711
                     /locus_tag="IXT22_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAQ4863695.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12686..13855
                     /locus_tag="IXT22_002364"
     CDS             12686..13855
                     /locus_tag="IXT22_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4863696.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14030..15409
                     /locus_tag="IXT22_002365"
     CDS             14030..15409
                     /locus_tag="IXT22_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863697.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15690..15919
                     /locus_tag="IXT22_002366"
                     /pseudo
     CDS             15690..15919
                     /locus_tag="IXT22_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5207 a         2809 c         3390 g         4513 t
ORIGIN      
        1 agtaggacgt cgccacgcaa aggcaaaaag atgaactaga aatagttcat ctttttttat
       61 ttttattaag ttaaagaacg gattcaattg cagcggtcat tttcaatgga gaagtttgtg
      121 gtgcaaatcg ttcgattact ttgccatttc tatcaatcaa aaatttagta aaattccatt
      181 ttattgcttt agtgacagta ccaggagctt catttttaag ataagtaaaa agaggatctg
      241 tattttctcc atttacgtca atcaattgat gcatagggaa ggtaacgcca taagtggttt
      301 tacaagcttc tgctgcttca gtcgctgaat ctagctcttg tttaaattga ttggaaggaa
      361 agcctaagat aaccagacct tgtgtctgat aagcttggta aagttcttct aattgtttaa
      421 attgaggtgc tagaccgcat tttgttgcag tgttaacaat gattatcggt ttgcctgcat
      481 attttttcaa tgaatagaca gtgccgtctt ctaaagtagt ttcaaaatta taaatagaca
      541 taaagttttc tcctttctat tttatataat aaaaagagcg ctaaactgaa aactagctat
      601 ttgttttccc gtttagaact cttttcagac aataaatatt taataaaata cgaagataag
      661 atagctatat tgcttctcat ctttacgttc ttttagaaac tatgcttcta cttcagacca
      721 ttcatcgcgt tttgctaaaa attcacgagc caaagcttgt gcaccttcta gtgtatggct
      781 ggcagcccag ccacattgtg tttcattgct tgcaggtact tcagtagctt caagaacatc
      841 tttcattgtt gcttcaagaa catctaaaat gtcttcgtag ctttcatgat tcaatacagt
      901 caagtaaaag cctgtttggc atcccattgg agaccagtct acgatgtaat ctgcgtgatt
      961 gcggattagt tcggcagtca agtgctcaag tgaatgtaga cttggcatgt ccatgtgttc
     1021 tttatttggt tgtttaaagc ggacgtcgta tttaatgatg acatcgccat gcgcacccgt
     1081 ttttcgatca gctacacgta cataaggtgc tttgactttt gtatggtcaa gattaaaact
     1141 ttcgacattc attctcattt gtaagactcc tatctgtttg ttcattcgtt ttgatgcttt
     1201 tcactaaaga attatttagt gaaatttaca aaaacgtctt tctacttgat tctaacactt
     1261 atcgtttcca aggtgtagca atctgaaata ttttttagat ttttctgcta agtcgtttat
     1321 tgggacttct agttcttgat tctgtcaaat gcctgagcta aatcgtttat gagatcctga
     1381 ccatactcaa ttcctacaga aagacggatc aagccgtcct ttatgccagc ctcttctcgt
     1441 ttttcttttg gaatagacgc atgagtcatg acagaaggaa tttccactaa actttctacg
     1501 ccacctaaac tttctgctaa agtaaatagt tggagtgatt caacaaatgg aatagcagat
     1561 tcttcatttt ttaaagtaaa agaaatcatt ccgctaaagc cgctcatctg ctgcttagca
     1621 actccatgga gttcatgatc gggtaatcct ggatagtaga ccttttctac tgctggatga
     1681 gaaaatagaa aatcagctac cacaaaagca tttttttgat gttcctccat acgaacactt
     1741 agtgtcttga ttccgcgctg aagtaaccag ctatcttggg gaccaagtac ggctccgata
     1801 gcattttggt aaaatccgat ctgatcggct agatctttat ggttagaagt cactaaacca
     1861 gctactacat cgctgtgtcc gcctagatat ttggtaccgc tatggacaac gatatcagaa
     1921 ccgagatcta aaggtctttg aaaataagga gtagcaaatg tattgtcagc aataactatc
     1981 aatccatgtt gatgagccag agtggcactt ttttctaaat cagtaatctt tagaagcgga
     2041 ttgctaggtg tttcaagata aagtgctttt gtattgggtt tgatggattg ttctatttta
     2101 tcaagattac tcgtatctat gatcgtgtac tcgagaccat ttttagtaag aactttgtca
     2161 aatagacgga atgttcctcc atagacatca tctcctaata agatatgatc gccagcttga
     2221 aaaagagaaa aaacggcatg aatcccagaa agaccagaag aaaaagcgaa tcctcgaaca
     2281 ccgccttcca aatcagcaat cagttcttcc aatgcaaaac gagtaggatt accagatctt
     2341 gaatattcat attgtttagg ctggccgacg ccatcttgcc gataagtgga tgtttgataa
     2401 ataggtacac tgacagctcc tgttgtggga tcttcactga tgcctccgtg gatcaatttt
     2461 gtttgaatgt gcatgtttct ttcctcctat aagtaaatgt tttttgataa atagcggtct
     2521 gctgcgtctg gaaaaatcgt aacgacacga tgaccaggtg gtaaacgacg aatttctctt
     2581 aatgctgctg caaaagccgc accactcgaa cttccaacta atagtccttg ttctcgtgct
     2641 aactgcctag tatagttaaa cccttctaca tcagagattg tctcgatctg attgattgaa
     2701 aggggagaaa gaaacggcgg aatgaattct acaccgatac cctcaatttc gtgaggggct
     2761 ggatcaccac catttaacac agagccctct ggttctacac cgattattcg aatgtcggga
     2821 tatttttctt tcaaaaaggt agaagttcca gcaaaggttc caccactccc aattcctgct
     2881 acaaaactat ggatattttc tttgatttca tgaaagattt ctggccctaa cgtatgatag
     2941 taagcagcag gattatcttt attttcaaat tgaagaggca gatagctgtt tgatatctcc
     3001 tctgcaagtt ttttactttt gctgatggca ccgatgattc cttgctcact aggagaatgg
     3061 atgatctttg ctcccaatgc tttcatcaat tgttgttttt ctaagctaaa cttctctgga
     3121 acaacaaaaa ccgttcttaa tttgtatgtg agtgcggcca gagcgatccc aattcctgta
     3181 tttccggcag ttggttcgat gatcgtcgtt ttttcattga tttttccttg ggcaaatcct
     3241 tctttgatca aataactgcc caatctatct ttgatacttc ctccaggatt taaatattct
     3301 agttttgcat aaatagcaga acctttaggc atagaatagt gctgattgtc aaagcgataa
     3361 agcggtgtgg aaccaatagc ttctgtaatt gtcgagataa tcatgtgggc ctcctaaaaa
     3421 aagataataa aaaaaggagc tgactattaa atcagctcct tgaaagacat agagaaaaat
     3481 tgagtagata aaaagataag ttacctggta ctcattctat gaagggcaat taatagacat
     3541 gacaaatagt atgctgcttt tatgcaccat acaacagcaa cgattcaatt gtttttggtt
     3601 gctgactgtc atgtgtatcc ctccaagtaa aatttttatt aacgatagca tgaaaaaaaa
     3661 taaaagtcaa aggcttgaaa gaaaaaaata tttcgatagc atcgtttacc cgtgtttatt
     3721 tttctgacaa ataggcatga gaccttaaaa gatagagaat actctagttt tctggccggt
     3781 tgtctgatac aataaagttg attatgataa agaaaagaag gagcaaaaat aatgatctca
     3841 gcaagtgatt taagagccgg tatgactttc gtacaagacg gcaaactgat taaagttctg
     3901 gatgcaagcc accataaacc tggtaaagga aatacagtta tgcgtatgaa actgaaagat
     3961 gtccgttcag gtgcaacata cgacacaacg ttcagaccag aagaaaaatt tgaaaaagca
     4021 catatcgaca caaaacctgt acaatatttg tacacgatgg atgatacagc tttcttcatg
     4081 gatttggaaa catatgagca atatgaaatt cctgtagaaa cagtagaaga agaaatgaaa
     4141 tatatcctag aaaacatgga agtaaaaatc caatttttcg gtagcgaagt catcggcgtt
     4201 caattaccaa caactgtcgt attacgtgtt gtggaaacac aaccttccat caaaggtgca
     4261 acagtcactg gttcaggtaa gccagcgaca atggaaactg gcttagtagt caatgttcct
     4321 gacttcatcg aaacagatga attgttggaa atcaatacag cagaaggttc ttatgtaaaa
     4381 cgtgcgtcaa aataattcgc taacggattg ataagaattt gaaaacagag cttgacctct
     4441 tgaaaggcag atcatcggat ctgcctttca agaggttttt tgtggaatca gcaaattgaa
     4501 aaataaaaaa gtatttgatt ttatttatat tttgaaagat gaatggcaaa agctagagaa
     4561 agaaaaaact gcacttattt atgaagaaat tgaaatgatt cataaaattg aaaatatccg
     4621 aactattccg aactatattg aagcgaaaat attttttcat cactaaatag tgttgaattt
     4681 atgtttttat gtataaatag cttctaatag ttcgggtatt ttgtttttat aaccattttt
     4741 attcttattt ttaaaaaaat atttcgaaat atactagaca attcagaaaa ttttgtttaa
     4801 tattattcca ataaaattca aatctttatc aaatgaaatt ccaataaaaa cggaaaaaaa
     4861 gtgaaaagag gaatgaaaaa atgacagaat tgataattgg cggagtcaca gcaagcacat
     4921 tggcagaaaa gtataagaca cctctgtatg tgtatgatga agaaaagatg agacaaacga
     4981 tgctgtcatt caagcgaggc tttgtatcga aacgttttga tacaaaagtg ctttacgcct
     5041 ctaaagcatt ccaaacgatt gagatgctgc atttagttcg tgaatatgga ttcgggctag
     5101 atgttgtcag tggtggggaa atctataccg ctttgcaagc tgattttcct agagatacta
     5161 tctacttcca tggtaacaac aagacgccag aggaactgat ctatgcactt gaaaatgatt
     5221 tgttgcatat tgttgccgat aatttgatgg aagttgaatt attagcagaa ttaagccaac
     5281 gctatttaaa aaaaatctgt atcatgcttc ggttgaatgt cggagtagaa gcacatactc
     5341 atgaatatat cgtcactgcg catattgatt caaaattcgg catgagctat gaaagtaaag
     5401 agtgccaaca agcccttcag ttgataaaag aaagcagcta tctagagtta gaaggatttc
     5461 atgctcatat cgggtcacaa atttttgatg ttactgcttg gttagctgaa atcgacaaat
     5521 tgacgaatta cttaaccgat tttgaccaac ctctttcctt gaatcttggc ggagggtttg
     5581 ggattcgtta tacacaaaat gatcagccga tcccagtcga agaggcacta aaaaaactga
     5641 ttgaatatac ggaagaagct ttggaaaaac gaaaactgac cattcgtcaa ttactgatcg
     5701 aaccgggtag aagtattgtt ggagaagctg gtacaacact atacacgatt ggtttcatca
     5761 aaaagacacc acataaaaaa tattactttg tagatggcgg gatgacagat aatatccgtc
     5821 cagctctgta tcaggcagaa tacgattgtg atttagcagc aaaactgtcg gaagaaaaaa
     5881 cagagaaagt gacgattgca ggaaaaatgt gtgaatcagg cgatgtggta attaaagaag
     5941 cttatttgcc gaaagcagaa tcgggtgatc ttttagctgt ttattccacg ggagcttatg
     6001 gatactcgat gagcagcaac tacaatcgag cgacacgacc agcagttgtt tttgtcaata
     6061 atggccaatc aagactgatt gttcgcagac aagcattttc tgatctacta aggggggaag
     6121 tttcctatga tccttcataa atataatggc tgcggaaatg attttatctt attagattac
     6181 gcagaagaca cagattatag tcaattagcc gcttctttat gcacaaaaga aaaatatgat
     6241 atagacggat tgatcgccgt aaaaatcgat ccgttggaaa tgatctatta caacaaagat
     6301 ggcagccgcg cgccgatgtg cggaaatggc attcgctgtt ttgctcgata cgtaaatgat
     6361 cagaacatga tgaatgaaca ggaattcaac gtagagacat tagcaggcac aagaaaaatt
     6421 acggtgttgg atccctcacc tttttattgc agcgtagata tgggagtgcc agatgattct
     6481 ccggaaaaaa tcaaagctaa tcaaacttat ccaataaaaa accaggaaat agagatcaat
     6541 ggtgaaaaag taacgatcac tagtttattt ttaggaacga ttcataccgt tgtttttgtt
     6601 gaaaatgcgc gtgaggaagt ctggagaaaa agaggtgaac tgatctgtca tcatcctttg
     6661 ttcaaagaaa aaaccaatgt caactttgta gaagtagtca atgaacaaga attgatcgtc
     6721 cgtacctatg aaagaggagt aggttggaca cttgcttgcg gtacaggttg ctgtgcctct
     6781 tatgtggttg ctaaggaaac tgggaaaatt tcagcagatc aggtagttgt tcacttggaa
     6841 caaggagact tgatgatctc tggtgaggat gcgatacaaa tggctggccc agcagttcat
     6901 gaatggacaa gaatattgga ggaatgaaga tgataaaagg ttcgatcgtg gcgctgatca
     6961 cgccgatgaa tgaagaggga tcagtagatt atgctggttt ggaaaaattg atccaattcc
     7021 atttagatga acaaacagat ggattattag ttttaggtac aacaggagaa tcttctacgc
     7081 tcacacaatc tgaggaggag cagatccttc aactgacagt aaagaaagtg gctggccgtg
     7141 tgccggtgat tgcaggagct ggaacgaata atacgaaaga aacgattgaa aaagcgaagc
     7201 attttgcttc tttgggggca gacgcacttt tggtcatcac cccttactac aacaaaacaa
     7261 gtgatgcagg actagctgct cattttacag caattgcaga agcctcaccg attccgctta
     7321 ttttgtataa tgttccttct agaacaggca tgtcgattcc aatccatgta ttagtaaatt
     7381 tagcagaaca tcctaatatc attggtttga aagaagcctc aggagatatg gcttatgtga
     7441 tggatgccgc tcggttgatt ggagaagaat tcttccttta cagtggaaat gatgatttga
     7501 tcctaccagt aatgagtgta ggaggaagcg gtgtaataag tgtatgggcg aatatccaac
     7561 ctaaaatagt ccatgaatta gtaaaagata cgcaggacgg aagatggcag caagcaaaag
     7621 aaaagcaatt aaatgcactt gaactgatcc atgccttgtt cagtgagacc aatcctattc
     7681 ctgtcaaagc agccatgtca ttattagact taccttccgg acctctacgc ctgcctttag
     7741 tttctctttc aaaagagaaa aagaaacaat tagctcagct tttgttaaaa gaaaggacgg
     7801 ttgaaaaatg aaaatcggac tgattggcag tggacagatg ggaaatagag tcgaagaagt
     7861 tgcacaagaa agaggagata cggtccttct tttacggacg gcacctaaag aagcaactac
     7921 gcttgctttt acggaactgc cagaactgct tattgatttt tctcatccag ataatttaga
     7981 gaaaatcctt tcgtatagct tatcatatca acttccgtta gtcattggca cgacaggtta
     8041 tacacaatca cagttccaag aaataaaaga acatgccaaa catgtacctg tgatgtatag
     8101 tgctaatttt tcgttcggca tcatggtgat gaatcaacta atcaagcaag cagctgcaat
     8161 gttgcaaggc tggcagatcg aactgattga aaaacatcat agtcgtaaaa aagatgcacc
     8221 atctggtact gcaaatatgc tgcttcaaac aatccaagaa gtgcaaaagc tgcagcccgt
     8281 atacaactgg caagggaaaa aaagagaaga aaaccaaatt ggtgtacaca gtattcgtgc
     8341 aggttcttta cctggtgaac atgatgtatt gtttgctgct actgatgaaa tatttacgat
     8401 caaacatgaa tctttttcta atcgaatctt tgctgcaggc gcagtagaag cagcggactg
     8461 gttgaaagat cagtcaccag gttattacaa attagaagat ttattaatgg acaaaggggt
     8521 gtaaaaaacg tggaagctca agaaatcatc cgctacattc aaacggcatc taaaaagacg
     8581 cctgtgaaag tctatctgaa tgtaaccgag ccaatcgaat ttaaagaaag taaagttttt
     8641 ggtgaaggaa gcagcttcgt tgtttttggt gactatgaga cgattgctcc ggttttagaa
     8701 gctgaatcag aaaaaatcat tgaaatcgaa atcgaaactg ctgcaagata cagcgcagtt
     8761 cctttgctag atattaaaaa aattaatgct cgtatcgaac caggtgctat tatcagagat
     8821 caagtgtcaa tcggcaacaa tgccgtgatc atgatgggag cgattatcaa tattggtgca
     8881 gtaatcggtg aaaacacgat gattgatatg ggtgctgtct taggtggacg agcgacagtg
     8941 ggcaaaaact gccatattgg tgcaggagct gtcttagcag gtgtgatcga accagcatcg
     9001 gccaaaccgg ttatcgtaga agacggcgta ctggtaggtg cgaatgcagt gattgttgaa
     9061 ggtgtccata tcggaaaaga tgcagtcgtg gcagcaggag cagtggtttt agaagatgtg
     9121 gcagcagaaa ctgttgtcgg tggaatacct gcacgtgtat taaaaataag tgatgatcag
     9181 acaaaagaaa atacagcatt gattgctgcg ttacgcgaat tatagaggag atggagaaaa
     9241 atgcgcgaaa tagatacctg tattgtgggg gcaaccggat tagtcggcca aacgatgctc
     9301 aaagtgttag aagaatatga ttttccagta ggacgattga aattattagc ttcaaaacgt
     9361 tcagccggta aagtttgtgt attcaagaaa aagaaacaca ctgtacagga attgacagaa
     9421 acttcatttg aaggatatga tttagcgcta ttttctgcag gtgcttctgt atccaaagag
     9481 tttgcgccaa tcgcacgaag tcagggacta tttgtcatag ataattcctc agcatggcgg
     9541 gaagattcgg atattccatt aatcgttcca gaggtcaatc tggaagacta tacattgaat
     9601 cggctgattg caaatccaaa ttgttcaacc attcaagcgg tacttccgct taaagcttta
     9661 caagaagcct ttggtatcca gcgagtcaat tattcgacct atcaagcagt ttctggttcc
     9721 gggcaaaaag gcattgaaga tcttcatcgt acgcaaaatg acgaggaacc agttttgtat
     9781 ccttataata ttagccaaac ggtgattccg gaaatcgatc agcctttgga aaatgggtat
     9841 acaaaagaag aacagaaaat gataaatgag acccgtaaga ttctgcatca gcctgctttg
     9901 ccagtatcag caacctgcgt acgtgtgcca atcgaaaatg gacatggagt ctctgtggca
     9961 gttcaactgc aaaaagagtt tacgacggaa gaaattagag agtgtctcag ccagtttcca
    10021 gggattcaat tagaagatga tctagcagca cataaatatc cgacgagcat tcttgctaga
    10081 ggaacagata tggtttatgt tgggaggatc agaaaagaca cttctttaga gaacggattg
    10141 ttgttctata cgactgccga taacatacgc aaaggagccg ctgcgaatgc cgtacagatt
    10201 gctgcagctt taatgcagaa aatagcggag gtggcaagat gagtaatacg ctgaaagtag
    10261 cgaaattcgg cggaacatcg atgtctcatg aagagcaatt caaaaaagtc cgtacaattg
    10321 ttctttcaga tcccaatcgc caagtgatcg ttgtttctgc tttaggcaaa cgtacgtcag
    10381 atgatgacaa agtaacagac ttactttatt tgatttatgc ttaccttcag catcatgttg
    10441 attggacacc cctttggaaa aggatttgtg atcgtttcat tcaagtaaga gatgttcttg
    10501 ccctgcagtt acctattgaa gatgaactag cacgcataca gaaacaactg gaagacgaaa
    10561 agataactga agattattta gtaagtagag gtgaatatct gactgctcaa ctgatggctg
    10621 agtatcttgg ttaccagttt attgacgcaa aagacctgat tttctttgac tatgatggga
    10681 aaatcgatca ggaaaaaaca gcacaggaaa tcacaaaagc atttaaaaga tatccgaaaa
    10741 tggttgttcc agggttttac ggggcgaacc ctgcaggaaa agaaaaatta ttgggccgtg
    10801 ggggaagcga cattaccggc gcgatactgg cgaagatgtt gcaagcggaa agttatgaga
    10861 attggacgga tgtttcagga atcatgatgg ctgatccgcg aatcatcgat catcctaaaa
    10921 tcatcgagga aatctctttt agagaactga gagagatggc ttatatgggg gctaacgttc
    10981 ttcatgaagc agctgttttc ccagttcaag aggctgatat ccccatccaa ataaaaaata
    11041 ccaatgatcc tttcgctcaa gggacaaaaa tatcgaatca cgaaatagaa aaggaaaatg
    11101 gactgacagg aatagctgga cgcaaggatt ttctttccat cactttattc aaacgtcata
    11161 tgtccgatga aatcgggttt atctggaaag caatgagcat ttttgctaaa catgagatat
    11221 caatcgaaca tattccttca gggatcgaca atatcggagt gatcgtctca gcagaagcga
    11281 ttgccgataa gttatttctc atcacgaaag aattaaaaga aacacttggc gtggaagaaa
    11341 tcgtcgtgat cgaagactta gctttgatct ctgtcgttgg gggtccgcat aaagaattga
    11401 ttggattatc tgggaaagtg ttatcgatat tgaacaaatt agaaattcgc acatcgatct
    11461 tatcacaagg agcacaggag ttgaatctga tcatcggtgt accgaataat caatatgaaa
    11521 cagtagtgaa gggtatctat gaagggatgg tgaatacgga tgctgaaaga atatcgaatg
    11581 gcactccatc aaattcctga aatcgggttt catgaattca agacaaaaaa atatttatat
    11641 gaacaagtaa aaaacagcga ggccgttatc catgaaatcg gcgaaacagg actactcctt
    11701 tattttgata atcagcaaga agaaacgatt gcttttcgaa cagatatcga tgcactgcca
    11761 gtcaaagaag aaacgaatct ctcttttgct tctaagcatg aaggttatat gcatgcatgt
    11821 ggtcatgacg gacatatggc gatgctttta gggttgactg actttataac taaacacatt
    11881 gaggatctta tttataatgt agtactgatc tatcagccat cagaagaaat ttccggtggc
    11941 gcacaaagcg ttattcagtc aggattgttg gataaatatg aagtacaagc aatatttggc
    12001 tttcatctat ggcctggact agctaaggga gaagttttct ctcgaccagg acctttgatg
    12061 gcacaaagca gtgaaacaga cattatcatt aaaggccagt ctgcacatat tgcttctagt
    12121 gaaaaaggaa tcgatagtct ggaggcagct gtacgatttt tgaagaatgt ttatgatttt
    12181 gaccggcaat taccggcaga gtggaatcat ctaatgaaat ttggccaaat ccaaggtgga
    12241 acgatccgaa atgttttagc tggagaagtt attgtatccg gaagtatccg ttcttacagt
    12301 tcagatatgc aaaattattt gaagagggga ttagaccatt tagcagaaca gtttcactct
    12361 acagctacta tttcttttcg ctataatgac ggctatccag ctgtaatcaa ccatagaggc
    12421 ttatatgcag cactgttaga ttcaaacaaa ctacatgaat tagatgctcc agttcttcaa
    12481 gccgaagatt ttggcatata tacgcaacaa tatccatgtg tatttttctt tttaggtgtc
    12541 ggtgataccc ctgctttaca tgatccgacg ttcgattttg atatggatgt tttagaaaat
    12601 ggtgtagaat ggtacaaaac gattcttttt acagaaaatc ttcttgtaaa aatcgatagc
    12661 agttcaaaag aggagcgagt aaataatgat gaatttatcc aatcgattta gtcctaggct
    12721 ttctagaata gaagtatcaa aaatacgaca attcgatcag caaatatcgt cgataccaga
    12781 tgtgatcaaa ctcaccctgg gagaaccgga ttttccaact cctgaacatg tcaagcaagc
    12841 aggaatagca gcgattgaag aagacttttc tcactatacc ggaatgagag gattagagga
    12901 actgcgggaa gcggcttgta tatttcagca acagcgttat ggattaactt atgatccgca
    12961 aacggaagtt ttgacgacag ttggtgcaac ggaagcgatt gcctctgcgt tgttatctgt
    13021 tttggaagaa ggagacaagg ttcttattcc agcgcctgct tattcaggat atcagccatt
    13081 agtggaacta gctggtgctg aattgatccc gatagatact tctgacacag ggtttgtctg
    13141 tcagccggaa caatttgaac gagcatttga acaatatgga tcagctgtca aagcagtcat
    13201 tttaaactat cctaacaatc ctactgggac gacattgtct gcaaaacaat tgaaagcaat
    13261 cgctgaggtt ttaaaaaaat atccggtatt tgttataagt gatgaagtat atgctgaatt
    13321 gacttatagt ggaacgcata tgtccatagc tacttatctt ccagaacaaa caatcgtgat
    13381 aagcgggtta tccaagtcac atgcgatgac tggttggcga gtgggcttta tttttgctca
    13441 aaaagccctt attgacgaac taattaaagt ccatcaatat ctggtgactg ccgctacaac
    13501 gatgtcgcaa aaagctgcgg ctgaagcgct aataaatggg gtgaaagata gcgagaatat
    13561 gaaagagcaa tatcaaacac gaagagacta tctggtccag caattggcgc ctttaggatt
    13621 tgaagtgacc cagccaaacg gtgcatttta cttgttttgc aaactcccag ctgccattca
    13681 aactgactct tggcagtttt gtgtagaatt agcggaacag gcaaaagttg cgtgtatccc
    13741 aggaattgca tttggcccag aaggagaagg ttatatccgg atttcttatg ctagcagcat
    13801 ggaaaaatta catgaggcct gcaaacggat caaagacttt ttaacagaac agtgattcat
    13861 agattttatc aaaaaaacaa tcgttaattt tgcggtatat tctgcaagga gacgattgtt
    13921 ttttaaattt agttcaaatg aacgcgtttc ttttgattca taactaatgt aatgttaagt
    13981 ttaaattgtt tagaatgatt ttaaaagaat attcaaggag gtttcatcaa tggaaaaaat
    14041 caaagttgtc attgtaggtg catctcatgg agggcatcaa tcgatcttgg aactattgac
    14101 acgatacggt gaaaatgtag atatcacgct atttgaagca ggagactata tttccttcat
    14161 gtcatgtggt atggagctgt atttagaaga caaggtaaca gatgtaaatg atgtacgtaa
    14221 tttcagacca gaaaactttc cgcaatccaa tgttcatatt ttaaataatc acgaagtaaa
    14281 aacgatcgat gccgataaaa aaacagtaac ggttactagc gcatcagata acgaaacaaa
    14341 agaatatcct tatgacaaat tgattttgag ttctggtgtc aaaccaaaca atctgccagt
    14401 accaggagca gatctagaaa atgtctactt gatgcgtgga tacaattggg caaccaaaat
    14461 caaagaaaaa ttaaatgatc cggctattaa aaaaatcgct gtcgtaggtg cgggttacat
    14521 tgggatcgaa gcagcagaag caagccgaaa agctgggaaa gaagtcgtat tgcttgatgt
    14581 gatcgataga cctttaggca cttatttaga tgctgagatg acagatattt tagaacaaca
    14641 cctaaatgaa aacggtattg aagttttgac aaatgcaaaa atcgaagctt ttactggtaa
    14701 cggaaaagtt gaggcaatca aaacaagtga aaaagaaatc ccagcagatc tagtcattca
    14761 agctgccggt gtgaaggcaa atacagaatg gttaaaaggg atcgtcgact tagatgaacg
    14821 tggctggatc caaacaaatg aatacttgca aacgaatctt ccagatgtgt atgcagtagg
    14881 agatgctaca cttgcttatt ctatcccagc acgcaaaaaa atgccgatcg ctttagcgac
    14941 tgttgcacgt agagaagcac gttatgtagt aaaacatctt tttgaagaag taccaaacaa
    15001 accgttcggc ggagtcgtag gttcctctgc attaagtgtc tttgactatc attttgcagc
    15061 aagcggattg aatagcttta cagcagcaaa agcaggagta gatgtacgag tgtcttatta
    15121 tgaagatacg ttacgaccaa aatatgtacc agaagaacaa ggaaatccaa aagtgtccat
    15181 ccaattattc tcggatccaa tgacccatca attgctagga ggagcagtat tatctaccta
    15241 tgatgttaca ggtcaaggaa atgtattggc actagcgatc caaaacaaac tgactttaga
    15301 agaactagca gaagctgact tcttcttcca gccaggcttt gaccgacaat ggagcatgtt
    15361 gaatctagcc gctcaacaag cgttaggaga agaaccattt gtagaataag aaaacgaaat
    15421 atttgaaaag aggttgtgaa aaagctgcct tgcatcaagt aataagaaca gccaagtaaa
    15481 aacagcttct tatgttttta acttggctgg acttattacc gcagatgcaa gcttttgaac
    15541 accgtttatt ttcaaaaaag ggactgtgac acgatttgtg taccgacccc caaaagttag
    15601 accaaaaaat ctaacttttg gaggtcggta ttttttatgg ttaaatatac ttttgaactt
    15661 aaattaaaga tcgttcatga ttatttggat ggcaaaggcg attggaccgt aaaaatccag
    15721 atcaagagat tgaagcggaa atgcttaaaa ttcgggagaa gcacaaggat tatggctgtt
    15781 tacggatgac caatgaacta agaaaccgcg gtttctctat caataaaaag aaagttcagc
    15841 gcttgatcaa gaagctagga ataaaagtaa cggcatacac gcgtaaatca cgtcgctaca
    15901 attcttatcg aggaaaagt
//
LOCUS       DACGLI010000064        15812 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.066, whole genome shotgun sequence.
ACCESSION   DACGLI010000064 DACGLI010000000
VERSION     DACGLI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.066"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            68..751
                     /locus_tag="IXT22_002367"
     CDS             68..751
                     /locus_tag="IXT22_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAQ4863698.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            753..1589
                     /locus_tag="IXT22_002368"
     CDS             753..1589
                     /locus_tag="IXT22_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4863699.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            1600..3354
                     /locus_tag="IXT22_002369"
     CDS             1600..3354
                     /locus_tag="IXT22_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863700.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(3630..3971)
                     /locus_tag="IXT22_002370"
     CDS             complement(3630..3971)
                     /locus_tag="IXT22_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4863701.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(4039..6210)
                     /locus_tag="IXT22_002371"
     CDS             complement(4039..6210)
                     /locus_tag="IXT22_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4863702.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            6421..7278
                     /locus_tag="IXT22_002372"
     CDS             6421..7278
                     /locus_tag="IXT22_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4863703.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(7349..8206)
                     /locus_tag="IXT22_002373"
     CDS             complement(7349..8206)
                     /locus_tag="IXT22_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4863704.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(8191..10893)
                     /locus_tag="IXT22_002374"
     CDS             complement(8191..10893)
                     /locus_tag="IXT22_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4863705.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(10906..12195)
                     /locus_tag="IXT22_002375"
     CDS             complement(10906..12195)
                     /locus_tag="IXT22_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAQ4863706.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            12345..13391
                     /locus_tag="IXT22_002376"
     CDS             12345..13391
                     /locus_tag="IXT22_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4863707.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            13393..15546
                     /locus_tag="IXT22_002377"
     CDS             13393..15546
                     /locus_tag="IXT22_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4863708.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT         4491 a         3303 c         2919 g         5099 t
ORIGIN      
        1 ttgctccgtc ttcttctctt gctgttctgc ttcattgcct ataaaccttt atgaaagaag
       61 agataacatg cctactatcc atattgccgg tgattctact gcggcagaaa aagatgaaaa
      121 caagcgtccc gagacaggtt ggggagaaaa aatctctgct tatttttcac ccgagatcca
      181 gatcaataac caagcaaaga atggacgcag caccaaatca tttatccagg aaggaaggtt
      241 agcccgtcta gcttcacagt ttcagccgaa tgatttctta tttgtacaat ttggacataa
      301 cgaccagaaa atccaagaag aaagaggtac gcttcccttc ggtagctatt taaaaaatct
      361 gcagatattt tttgaatgcg caaaaaaagc gaacgtccaa atggtcttac tgacatctgt
      421 gacgcgacga gattacttag aaaacggaac attgaatcca gatatacttg gagactatcc
      481 aaaagcgatg cgtgcatttg ctgagaaaca ccatattcct cttttagatg tgttctcaag
      541 atcacaagaa ttgttccaga ccttctcaaa agaagagaca aaaaaattct acctgcatct
      601 tatgcctgat acttgtaaaa attacccaga aggactaaaa gacaataccc actttagtcc
      661 agaaggcgct gataaagttg cccgaataat tgttgaattg ataaaagaat cccgtctgcc
      721 tcttgctaat tatttacaaa aaggagtttg agatgtttcc attaaattta ggcatccgtg
      781 cccacgattt agatgttcga aatcgtgaag aaatcgttca aaaagtatca cagcttcact
      841 tgtcccatat ccaatttgca ccacaaaaag catttcctga acaacttaaa ttaactgaca
      901 tgacacttgg gagtgctgcc tattttggtg aatacttcca aaaaaacaat atcgaacttt
      961 ccattttagg atgctatatc aacctatcca gcaaaaatca agaagttcgt gcacaagcat
     1021 tggcaacttt caaacagcaa attgctctgt gctctgccta tcaagccaag atgattgcta
     1081 cggaaaccgg tagtgtctct gtcggttaca caaaagaaaa ttttactgaa gaagcttatc
     1141 agatcgccag aaattctatc attgaattag tcgctcatgc agaaaatttt ggcgtaactg
     1201 ttgctgttga agcagggatc aatcatccaa tctataacta tcagttagct aaacgtttaa
     1261 tcgatgaagt agcttcacca aatttaaaaa tcattttaga ttgtgcgaat ttgatgcata
     1321 aagaaaatca tgctgatcag gaaaaagtga tccgaggtgc cttggacaat ttacatggtt
     1381 atattacagc gcttcatctc aaagactata tcatggaaaa tggaaagatc cgcatggtac
     1441 ctgttggcaa gggctgttta gatttccgcc cggtactgca ttatatcaaa tatgagcgtc
     1501 ctctaatgta cgccactctt gaagctactc ctgagattta tgttcctgaa gcaatagaac
     1561 acttgcagtt tatttaccaa gattgttaag gagaagatta tggaggaacg aatacagaaa
     1621 agttatcaaa aatatcatgc aaatgctttt cagacattgc tgcatcttta tcagggaaat
     1681 tattggcgtt ttgccatgtc aggactcttt tttattatca aacatcttcc atcttggtta
     1741 atgccgatcg ctattgccaa tgtaatcaat gcagcttcat cgaaagattc ttctcagttg
     1801 caggccattt atttcaacgc ttttttgatg gcttgtctga ttggtcaaaa tatattgacg
     1861 aattattttc atgtaaaata ccatagcact tcgatccgtc aagtagaagc tggactaaga
     1921 gcgaccctta tcaagaaaat ccaagaacta tctattcctt atcaaaaaga attgcaatct
     1981 ggacgaatcc agtcaaagat catccgtgat gtagaagcta tccaaacgtt gtcctctcaa
     2041 gtatttgtca gcggattaaa tatcgctgtc aatttattcg tagctttagg tatcacgctt
     2101 tataaaagtc ctgttgtttt catgtttttc ttattgactg ttcctctcgc cgcattcgtt
     2161 actctctttt tccgtaaaag gatcagacag tccaactcag acttcaggca agaaatggaa
     2221 gagacttctg caaaagtgat cgaagtgatc gaattagcac cgattgctcg agctcatggg
     2281 ttagaaaaac acgaaacaac tcgcttaaat aagcatttta ctcaaatcta tgaaaaagga
     2341 ttccacttag atatcctgca atctgttttc ggatcagtca gctgggctag ttttcagata
     2401 tttcagctga tttgtttgag tttcactggg atattagctt tacaagggcg catccaaccc
     2461 ggcgatgtcg tgatgtatca gacgtatttc acgacgatcg tcaattccgt ttctggaatg
     2521 atcacgctga ttcctacgat ttcaaaaggc atggaatcta tcacttctat tggcgaactg
     2581 ttgattgctg gcgatgtaga aacttatcac ggtaagaaaa aaatccaaca tttggatgga
     2641 aattttcgtt ttgaggatgt ttcttttctt tatccggact cactcaaacc gattatcgat
     2701 catttttctc tagaggtgaa agctggagaa acaattgctt ttgttgggcc atctggctct
     2761 ggaaaatcta cactccttaa cttattgatt ggatttatcc agccgacttc aggaaaaatt
     2821 tttctagatg atcagccttt ggatgaactg gatatgcgaa gtgtgcgaaa ttatttagcc
     2881 gttgttcctc aaaccacttt gttgttctcc gcttcgatca aagagaacat cacttatggc
     2941 ttgaaaaacg tatcaaaaga acgtttagat gaagtcatcg aagctgcgca actttcttca
     3001 ctgattgacc agcttcctga tggtctggat accttagtag gcgaacatgg caacaagctg
     3061 tctggtggcc aaaagcaatg tatctccatt gcacgagcgt tgatacgtca gccaaaaatc
     3121 attttgctag atgaagcaac ctcagcttta gataaccagt cagagaaaaa aatccagcaa
     3181 gccctgaatt acctgacaga aacacccact acttttattg tggctcatcg gctttcaacg
     3241 atcaaagagg cagataaaat cgttgtgatc gatgaaggaa aaatcgttga aataggtact
     3301 tacgaaaaac tgttagctca aaaaggctat ttctaccgct tgaaaaatga atgacaaaaa
     3361 ataggagcta tgacaagact tttgtcgtag ctcctatttc tgaataaacg gtgttctcct
     3421 gccaactcct cggtcacaag tcacaatagt catcaaacat gagaagctgt tttttgaaat
     3481 tgttccttgt aactcagagt taaacggtag gctcacgacc tcttggtaaa tggtgttcaa
     3541 gagacagcct atcggcaata agaagcaatt ttgtcatcgc tcaaggccga acgtctcttt
     3601 cacaccctct gttgtttcat aaaatagttt tattcgctgt aaaggtcgcg aactggtgtc
     3661 atgatgatac ggttcaagtc attgatgatt gtactgaagc cttgctcttt ttgcatcaag
     3721 tcattgatta cttcttctga ttggattttc acagccattt cttgtgcttt cattgcatct
     3781 tcgtcgctga actcttgtcc actcatttgt ttttcttgta attcgatttg catcgcttgg
     3841 aagtctttga acagtttgtg tgcttcttcg tttgcttgta ctttctcgta cgcttctttc
     3901 aacgctttga attctggtaa ttcacggatc tcacgttcga tttgattcgc gctatcgtag
     3961 atgtttgaca tgttatgccc tcttttcttt tagtagttac tctctattgt aacatggggt
     4021 tattcgtttt caaaggggct actctccttg atatttccgc cagaggtctt tagccgcttc
     4081 accaattccc tgaacgcctt ctttcaccat atcgccgaag tttttcagcc cttcttttgc
     4141 ttgttcacca tattgattca agttatcttg ccaatttcca gactctccat tagaatttcc
     4201 tgtgtttcca acttgatctg cagctaccac ttgtcctcct gtggcatagg catctgctac
     4261 actaaatcct gtttttgaag tatacggaag gatgccttct gccgctgatt tgaagacttt
     4321 cccgacaaca tttccacttg tcccttccaa atagtgcagc ttgctggatt cttcgtaacc
     4381 catccatgtc gaaatcacta cgtctggcgt gtaaccgatc atccattggt catttgcttt
     4441 tgtggcatcg aaattagttt ctgtggttcc tgttttccct gctatcgtat aacctgcagg
     4501 attcgcagca gccgctgttc catttgaaaa tgtaccaaga agcatgctgg tcatttcatc
     4561 ggctgtttcc tttgatatga cctgttttgg ttttttgttt gtgttatcga cgatcaccgc
     4621 tccagtcgaa tcaacgattt tcgtgataag atgcggcgta tacatctgac catcattggc
     4681 aaatgcactg taagcacccg ccatgatcaa tggagatact cctttttcca gtccaccaag
     4741 ggctaagcca taatacttat cagattttgc taaaggcagg ccgaattctt ctgctttatc
     4801 atatcctttt tgtaaaccga tctcatgcaa aagccataca gcaggcaaat tcaaactttg
     4861 tgcaacagct tgatacatcg gtacttctcc ttggtatgtc ccgtcaaaat tatgcgcatc
     4921 gtaataactt tgcggttcgt ctttcaagat actggaaggc ttgtatccag cttccagtgc
     4981 tggtgtatat acgcttaatg gtttgatcgt tgatcctggt gaacgacgca tctgtgtagc
     5041 aaagctgaat cctctaaaga catgatctcc tcttcgtcct actagtgctt gtacaccacc
     5101 tgtattcgga tctaaagcta ctgaagcaga ttggaccatg gcaccatctg aagcatttgc
     5161 tgggaataat gcactgtttt gataagtagc ttctaattgc ttttgataat cctgatctaa
     5221 agctgtatag attttatagc ctttattcat gacatcttct tcatcaagac catactcgtt
     5281 aactgcttca tcgatcactg catcaaaata ataaggataa cgataaccag aatctgaatt
     5341 atcgtatgtg tcattaagat acgcgctgat atctgtctgg ctttctgctt gttcttgttc
     5401 ttttgtgatt tttccgtttt cttccattac acttagtact gtgtttttcc gatcattcgc
     5461 attttttggg tgatcgatcg gattataaat accaggacct ttcagcattc ctgccaaagt
     5521 agcagcctca gacagcgtaa cattcgttgc atctactcca aaatactttc tggaagcgtc
     5581 ttggacaccc cataccccgt tgccaaaata ggcattgtta agatacatgg tcaagatttc
     5641 ttctttgctg tacttctttt cgatctcgat tgccaaaaat aattccttcg cttttcgatc
     5701 aaacgtttgg tctaatgtca gatacgcatt tttggcaagc tgctgagtga tcgtacttcc
     5761 tccgccccct gatgttccgc cagacaagac cattcggact gctgcacggg caatcccttt
     5821 gatatcaaac ccgtgatgct cgtaaaaatt cctatcttct gtcgagatta ctgcatcttg
     5881 gatataggga gaaatcgcgt ttaattctac atatgttcct ttttgggcgt acagtgtgcc
     5941 agcttcttcg tttttcttat cataaatgac tgtcgattgg cttaatcctg attttaacgt
     6001 ttcgacattt gcttgttttg ctaaaataaa gaggtagata cttgtcacta agacacagat
     6061 caaaccaatc agcaaaatca atttgttcac atgatatttt ttccagatgc gctttcgcca
     6121 tcgatggaat tgtccgagat atggtctgat ccaacgccaa aaactgatca aagcagcttt
     6181 tatcttttct aaaatgcttt gaaaatccat ttgcttcttc tcctgtctat ttgattcaat
     6241 cgtcttattt taccatagtg aaagagtgtt ttcttcctgc ttaagttgta gttcaatatg
     6301 tttttttacg ttagtgcaag tagagtaaca taagaatgaa cagaaaaatg taagtttttt
     6361 cttaaatatg ttttaaaaat ggtacaatta gtctgcaatt gcactgaaag gagtacactt
     6421 gtgaaaatca cgatcacttt acctatgaac catcctgaaa caacaattcg cgacttgctt
     6481 gaaaaggaat ggttagttcc tagaaaggtt cgacactttt tgcgtatacg taaaaacgtt
     6541 tggatcaatc aacaacctgc tttgttccat catgaagtaa agggcaatga ccagatcaca
     6601 ttgttattcg aagaaacaga ttataattat caagaagttc aattaggaga tgcgaagcac
     6661 atccgtgttt tatatgaaga tgagcatttg attatagtgg ataagcctgc aggaatgaag
     6721 actcatccaa atgaaccgac agaaaacagt accttactca atcatttagc tgcttatctc
     6781 gacactaaac agcaacgacc ttacgttgtc caccgcttgg acaaagaaac aagcggtgcc
     6841 gttttatttg caaaaaatcc atttgtcttg ccgatacttg gaagaatgtt ggaacaaaaa
     6901 atgatctatc ggagatatca agccatcgta tggggagaaa ttgccaaaga tatgaccatc
     6961 accaataaaa ttggacgaga tcgccatgat cggagaaaaa gggtcgtaga tgataaaaat
     7021 ggtcagagcg ccttgacaca tgtcactgtc aacaaagtac tttctgaaca aacacaagtc
     7081 tattgtgttt tggaaaccgg acgtacacac cagatcagag ttcatttagc tcataaggga
     7141 catccgatcg ttggagaccc tctctaccaa aatagaacag ctgaacgact gatgctccat
     7201 gcattagaac tgcacatgat ccatccattt actcaagaaa aaatagtcgg taaagcttta
     7261 cctggattat gggaatagaa ataaaaaaga acagagtctt atcagcagat aatgataaga
     7321 ctctgttctt tttgtgtaat ttgtctgctt acttttgatg ttcgtgttct gctaacagca
     7381 aactaccgat aatcccactt tcattcggca gtccccaacg aacgatatat tcacttactt
     7441 gaggtgtttc catataacca cccatcaatt caacaaattg ctgacggatt ttttgaagga
     7501 gatgatcctg attcattacc ccaccgccta aaataatctt ttcaggtgct aacgtcaacg
     7561 tatagttgat cagtgcttga gcaatataat aagcctgaat agcccaaaca ggatgatctt
     7621 gcggcagatc ttgccctttg atccctgtgc gtgcctcaat agacggtcct gctgctaatc
     7681 cttctaaaca atctttatga taaggacaag taccttcata atggtcatct ggatggcgtt
     7741 tcacccaaat atgtcccatt tcaggatgtg cgatccctga aaaaatttct tcattgatca
     7801 cgacacctgc accgattcct gttcccacgg taaggtaaat acaactattt tttccttgtg
     7861 ctgctccttg cttcaattcc ccatatgcag cagcattgac atccgttgtc caagcagcag
     7921 gaatattgta gcgttccttg attgtgccaa gaaaatcgaa ttgtgcccac ccttttttgg
     7981 gagttgccaa aacgtatccg taattatctt ttgttttgtc gataccaatc gggccgaatg
     8041 agccaatccc gattcccttc aattcataac gatcaaaaaa ttcaaatacc tgatccaatg
     8101 tttcttctgg tgttgtggta gggatactta atttttctaa aatttctcca ccatctgaaa
     8161 ccgcacacac aaattttgtt ccgcctgctt ctattccgcc atacattcgt tttcctcctc
     8221 gaatccgatt gtccgaatct cataaggttg gattattggg acaaccgctt gcttcgttgg
     8281 ttcttcaagc agattcaata tgacagtttt tccattgtct ttagttattt ccaatttttc
     8341 taaatgacta gacatattga aacctcttac tactacttta tcactaaact tgctgcgttt
     8401 caaagctgta attgcaaacg tttcactttt tatcgttaaa tattgttgtt ttgaaatcaa
     8461 tgttccttca tgatgtttga tttgttgagt ggaaaaagga atctgtgctg cgtatgcatg
     8521 caaataagta gagaattttt cttctggtcc atgtagttca atgctgtaat tgaaccgatg
     8581 ctcacctaga cactgtgctt ctggtgttgg aaaatatccc caatcgccta gttctcccac
     8641 actgcgaagt agcgtcactg cgatttgtcc gtcttctgtt acttcatatt cattcaaacc
     8701 aaagtttccg actgttacac cgtactcttc atcatgaata ttgacaaatg cttgctgatg
     8761 ttgcggattc gtggggtttt cccaactttt agacacatgg tttgggcgct tcaccacttc
     8821 aaaaatacta tctgcttcgt gatgttccac atgtaacttt gtaggaaaca agacacgtaa
     8881 gcgatgatct ttcatctgat tgtcgagagt cgtttcaaag tcgatttttt tactatcttt
     8941 tctgattgtc atgattgttt ttatttgaag gattcgtttt tctttggatc gttctgcttt
     9001 tcgataacga aattccacaa ccatctgctg ttctttttct aaacgctcgt ctgcagaaac
     9061 agggatttcc atttcctgta gaatacttat ttttgctatt tccggtgtat ctactaatac
     9121 ttttacttca gagttttctt tgttactgga taggattggc tgatcacaga aaggttgttt
     9181 aaagatatac tcatttccta tatcgccgat atcttcaaaa atatgcagat tattcaactt
     9241 tcgtttgttt ttgcgatctt ccattgtaat ggtaccattt ttttcaatcg tcaaatgtag
     9301 agggccgttt tcgatgattc gtccactctg atgaatcatt gtttcctttt cttctgcttt
     9361 cgcttcccct tctacaagcg cgaatgtttc ccaagaaaat gctggcatgt tttctaatgg
     9421 taaagtcact ttgatcattc ttgccatata tggcacacgg aaacggtctt tcggcaaatc
     9481 ataaccaaat tggacagttt cttcagataa aatagctggt atagtggccc cactttttgt
     9541 ttctacatga tacttacgtt taggcaaatt ttctaactct tgatatagtt gttcaggtat
     9601 tccttcagcg aatctttttc tttctaattc gatggttatt tctgcttcac cagttttatc
     9661 cattcctgca gtatttacaa tgacaaatgg aaagctgtct tttgggaatc cggtcgtatc
     9721 gattgctgcg gtcagctgtt ctaaggaatc ttgtgcaaga tactttccaa cttcatctgc
     9781 tttttcaaaa cgaggtatca tttcccgatg gacagaatcg actgaacaac cgcaaatact
     9841 gtcgtgagga tgattttgca ttaatgtctt ccaagcataa tctaattgat catggggata
     9901 gtttccacta acttcataag ccatcgtcgc aagtggttct gtaatatttt ctagctgtcg
     9961 ctggaccttg gtattccatt gttttaagta aacccgagca gatgctgtat tggctaaagt
    10021 ataccagcca tccgtttctt gacttgtcaa ttctccttct actgagccta agtcttctgg
    10081 cacatctttt tgaactgctt ccagatagtc agtaaaatta gaatgaataa actcgtaatc
    10141 tggaaacagt tcatttgcga gatggattgc ttttgatata tctttttgta ccggttgatg
    10201 atcaacacca ttcatcatca ataagtggtt cgtagaggca tattgttctg catccgctaa
    10261 tttttgcttc caaaaggcaa gagctgcttc tttttctact ggaatctcat tcccgttgct
    10321 ataccaattg gcaaatagca gaccaaagat tgctgtttga tcagggcctt tccaccacat
    10381 ctctgagtat tgggaagaat agttttctgc ttccaaaact tgattatcaa agccaattgg
    10441 ttttacacca cggccaaacg ctgctgctga aataccagct tgtttcatta attgaggcgt
    10501 ctgtcccata tttccaaatg tatcgggaaa atagcctaac atgacagggg ttccccattt
    10561 acggctttct tccatgccaa tcagcatatt tctcacgttc gattccgagc tgataagaaa
    10621 atcatcttgc aagatataaa atggtccaat tctcaatttt ccttcattga ttgcttgttg
    10681 gattgcctgt cttttttctg gccttacttg aagatagtca tctaaaataa tcgtttgccc
    10741 atccaaatga aaactgttga aggacggatc aacttcaaat agctctagta gatcgtctat
    10801 caattcaatc agtcgcatgt gatgctgttc gtaagccatg taccattcac gatcccagtg
    10861 gctatgagaa atgatatata ctttcttttt catttacgat acctcctact tttctactct
    10921 aatatcaaag taatccatga ctaattcgca aaacatcata tttgcccaag aaaaccattc
    10981 tctcgtataa ttttcaggat tgttcacatc gaatccttcg tgcataaggt gtgttcctgc
    11041 gtcagttgct acaagtaaat tcaatatccg ctctttttca gatttgtctg acgttgtcat
    11101 tccttccata gctaatgcaa tcggccaaac gtatttttct ggcgtatggg aggatccaat
    11161 tccttttgcg tactttcctt catagaaata tggattttct ttactcaaca atgttcttct
    11221 tgtttgcaga taatcttcct cttgttcaga acaatatccc aagtaaggtg cggcgatcag
    11281 attgggcaca ttactgtcat ccatgactgt ggcgtttccc attccatcta cttcatatgc
    11341 ataaatcgtt tgcccttttt gattaaccgt tcgtccgtga ttctgaatcc cctcttggat
    11401 ctctttcttc aatttctgtg tttgctgtac aatttcttta tcatcgagta tcgtttgaaa
    11461 aatttcttcc acataaccta acacgaccac cgcaaacata ttggatggta ccagatatcc
    11521 ataacggcaa gcatcatcgc taggacggaa accagaccat gtcattcctg taaaagctgt
    11581 ttttgcacct cgcccgtcat tgatcagcgt atcttctttt cttgtcgtgt ctcgtacaaa
    11641 tgtataagga gagtgttcat gatcttgctc tgttttgaac acgtccaaga tttttttgat
    11701 accttcaata aaagattgat tgaattgatc agtttttcct gtatttttgt aaagaagata
    11761 ggccaactgt attgggtagc ataaagaatc aatttcatat tttctttccc agatccaatc
    11821 gttcattttt gtatgatctg tttggtggcc agcaccgtta gcttcttcgt tgaaggcatt
    11881 cgcatatgga tcgatattga tataaaaaaa ttgctttttg actaacccgc tgatcatgtc
    11941 agctaattcc tcatcttctt ttgcaatcac taaataagga cgaacttgtg cagtagagtc
    12001 tcttaaccac atcgctggaa tgtctcccgt caataaaaag gtggttccgt cattttgctt
    12061 tttgactgtt gtcaacagag tattggcaaa tgctgctgta aaattctttg cccagtccgc
    12121 atggatatcc ccacattttt gtgtgatatc ttccataaat ttctgcaccg attttggtat
    12181 atctttataa accactaata aaaccttctt tctatttgat atatctttaa agattatact
    12241 tcatacagcc aattatgtct acgctttcaa aaaatatctt tttatttact ttttcatcca
    12301 ttatggtatt atttgaatat gatatatcat taagaggtgt ttatatgact caaccattgt
    12361 accagacaat atttaatgat ttgcaaacgg ctattttaac tggtgaatta cctgtagaca
    12421 gccaactacc aactgaaaaa gaactttcac gtacctataa agtaagcaga atcacttcca
    12481 aacgtgcatt gactgaatta gagcaattag gacttattta tcgcgttcgc gggaaaggca
    12541 gtttcgttaa atccgcttct ccggaacaga ttcttgcttc tcctacaaaa acacgacgga
    12601 ttctgtttct tcttccatat gtcgctgatt tgtctgttgg tgattttagc aagggattga
    12661 accctgtgat gcaagataaa cagattgatg tcatgatgac gacgcttgac tttctacaaa
    12721 ataaaacagc aaaagagcta atcaatgaat ttgacggatt gatttattat gctcttgata
    12781 cagaacaaca tcttgactta ctttttgagc tttcattgaa agaattccct gtcgtcatat
    12841 tagataaaaa aatctatgag ttaccttttc ctaccgttct ttccgataat ttccaaggcg
    12901 gtgcgcttgc tgcctcttat ttgatcgaac agggacattc aaaaatcgct tatttgtttg
    12961 gtacgcagac tcatccacaa tccgttcgac agcgttacct tggttacctt gaagcattgg
    13021 acaaagctgg tttgactttc cacacttcac tggatgacaa aagcgcgaca ttagatgaat
    13081 tgctttctta tatcactaag tatgaagtaa ctgcttttgt ttgtgaaaac gatgttgtcg
    13141 ctatccagac catgaatctc ttgagacagc atggttatca tatccctgaa gatttttcaa
    13201 ttatcggatt tgatgatatc caagcagcag ctcttgttga cccgccactg acaaccatcg
    13261 cacaagattt tgaacagtta ggtaagcttg cgggagatgc tttggtcact tggttagaga
    13321 caaaagatcg accatccgat agtaaatttc cagtttcatt catcaaaaga caatcaacaa
    13381 aggagaaata aaatgaatat cggtcaaata gatactagac atgcaacagc gaatcagcca
    13441 aatttctcta atgggaactg ccagccttat actggcgttc cttttgggat gaattatttt
    13501 gcaccgcaaa ctacggatca aaacggcagc tggtggtttc atcctgatga ccgcgttttt
    13561 caaggctacc gtcttaccca tcaaccaagt ccttggatgg gtgatttcag tcatatgctg
    13621 tttacgccga tcaatggaaa actacaggag aacacccttt tccatgctca aagttcttac
    13681 cgcccagaag aaagtatatt ttgcccgact catctgtcga tctgtcaatt acgttatggc
    13741 atctgttcta cattgatacc tagcatgtat ggcggaatct tatctattga ttacagcaaa
    13801 aatgacagcg gtttactttt atcctttccg ggacgccatc agctctttgt tatagatcct
    13861 tacacagtgg aaggaaaaat cacacatttt gctggttcag aagatcctga tttttctttt
    13921 tattttatat tgagatttga atatccttta acaattgatg agttagctgt ttccaacaaa
    13981 aatagcgact cgatcccgtt gtattttgaa cagacaaaaa aacaaactat ccgatttggg
    14041 acatctttta tcagctcgga acaagcagct tataacctgg aactagaaca aaaccaaagc
    14101 aaagagactt accttgctca cagtcaagaa caatggcagt cctattttga tcgtatacag
    14161 ctcacacacc atgatcaaca acaattgcgg acgttttatc ataatttata tcgggtgttt
    14221 ttatttccac aaacatttta tgaaattgat cctagtgggc aaaaaatcca ctatgatacg
    14281 actagtcgat ctataaaacc tggtgttctc tatacaaata atgggttttg ggatacgtat
    14341 aaaacggttt atcctcttta ttctttgatt gctgtagaaa aatacgaaga aatgctggaa
    14401 ggttttttga acagctatag agaaagtggc tatttgccaa aatggctgtc tcctgatgaa
    14461 cgtggactta tgcctgggac attgatcgat gcggtcattg cagatgctgc tgtaaaagat
    14521 atccgacgag acttgatgcc tgaatttcta acggcaatgg aaaaaggtgc tacggttcaa
    14581 agcaaacatc caaattatgg acgccaagga acagaagatt acttgacata tggctatgtt
    14641 cctaatcact accacgaatc agtcaatcac acattagact atgcttatag cgatttttgt
    14701 attagccaag ttgccaaggt actagaagaa gaggaaatga cgaagaaata tcagcagcaa
    14761 tcattgaact atcaaaatat ctttgactat gagtcaggat ttatgcgttc aaaagataaa
    14821 gatggcaagt tcagagaacc attttcagct aatcgttggg gacaagatta tgcagaagga
    14881 agtgcttggc aaagcagctt tgctgtttat cacgattttt caggactgat cggaaaatat
    14941 ggtggcagtg agagatataa agaaaaactc attgagctgt gcaatcagcc cccaacgttt
    15001 gacccaggag gatatggttt tgagatccac gaaatgagtg agatggccgc gatagaattt
    15061 ggacaattag ctatttcaaa ccagccaagt tttcactatc cttacttgtt cagttatata
    15121 ggacaacctg aaatggcaca gccactgctt aaacagttga tgactcagac cttcgacgat
    15181 tctccaatgg gttaccctgg agatgaggac aatggaagta tggccgcttg gtatatcttc
    15241 aatagtctgg gattttatcc tgtcacgcct ggaaccggtg aatatgttat cggtatgcca
    15301 ttaattgaca aggctgtttt gcttttgtca aatggaaagg aattgacgat tgaagcaacg
    15361 cctaatcggc cgcagcaaca atttatccat aaaatcaaac ggatggacag agaatatacg
    15421 aaattatatt ttacccatca agatttgctg aaaggcggca cgatctctta ccaattaggg
    15481 atcatccctc accctaagaa atatcaagca aaagatttgc ctttttcctt atcaaactat
    15541 aattaacaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaagcaaa
    15601 aatagatcct catatttttc gtttggttgg tcttattacc gcagatgcaa gcttttgaac
    15661 accgtttatt gagaggttgt gaaatcagcg ttctgacctg agtattagag agacaaatgg
    15721 caaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca gctgattgaa
    15781 caccatttag tggagaggtc gtgaaaaagc tg
//
LOCUS       DACGLI010000065        14575 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.067, whole genome shotgun sequence.
ACCESSION   DACGLI010000065 DACGLI010000000
VERSION     DACGLI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.067"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(18..293)
                     /locus_tag="IXT22_002378"
     CDS             complement(18..293)
                     /locus_tag="IXT22_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863709.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFRKQMKKLIEKEFPRSHKLYVNQQF"
     gene            587..1402
                     /gene="thiD"
                     /locus_tag="IXT22_002379"
     CDS             587..1402
                     /gene="thiD"
                     /locus_tag="IXT22_002379"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAQ4863710.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFKLIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1607..3058)
                     /gene="cls"
                     /locus_tag="IXT22_002380"
     CDS             complement(1607..3058)
                     /gene="cls"
                     /locus_tag="IXT22_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4863711.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3400..6066
                     /locus_tag="IXT22_002381"
     CDS             3400..6066
                     /locus_tag="IXT22_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4863712.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6430..7182
                     /locus_tag="IXT22_002382"
     CDS             6430..7182
                     /locus_tag="IXT22_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4863713.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7204..8358)
                     /locus_tag="IXT22_002383"
     CDS             complement(7204..8358)
                     /locus_tag="IXT22_002383"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAQ4863714.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8543..10984
                     /locus_tag="IXT22_002384"
     CDS             8543..10984
                     /locus_tag="IXT22_002384"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAQ4863715.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11314..12018)
                     /locus_tag="IXT22_002385"
     CDS             complement(11314..12018)
                     /locus_tag="IXT22_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863716.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12205..12450)
                     /locus_tag="IXT22_002386"
     CDS             complement(12205..12450)
                     /locus_tag="IXT22_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863717.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12467..13318)
                     /locus_tag="IXT22_002387"
     CDS             complement(12467..13318)
                     /locus_tag="IXT22_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4863718.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13483..14487
                     /locus_tag="IXT22_002388"
     CDS             13483..14487
                     /locus_tag="IXT22_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAQ4863719.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         4682 a         2557 c         3027 g         4309 t
ORIGIN      
        1 taaagaacag ttagaagtta aaattgctga ttcacataga gtttatgact tcttggaaat
       61 tctttttcaa tcagtttttt catctgttta cgaaattctt ttttttcagt aaacataaag
      121 gtttgggtat cgtaaccttc ttcatgtagg aaatagatta ttcctttttc tgtgttttgc
      181 gtataagctt ttatactcct gtcttttttg aaagaacaga tcgtatagcc atctatttgg
      241 tctggtagtc gtttgatttt cttcaaaatg acttttttat cctcaagttt catttttttc
      301 acctgacttt atttttttca tatggaaatc atagcgcctt tggttatatg aaaacaagaa
      361 ggatactgaa atatatataa atcaaatagt ggttatttat tattagaata gcgaatacaa
      421 acaaatgaca actattttct gatttattac aaatgttttt tcaaataaat ttgattacca
      481 agaaaaggta gtggtatatt tactgaggga tactttgaaa aacatatgat agaaacagta
      541 acagcattat gaaaaatctt tttataaaaa tggaggaatc gatttgatgg aagatcagta
      601 tgtacaagca atgacgatcg caggatcaga tagcgatgga agcgcaggga tgcaagcaga
      661 tatgcataca ttctttacaa gaaatgttta cggtgtttct gtcatgaccg catgtgttgc
      721 aggtaattct tacggaatcg gagcaagtgt gacattgcca acagatttta tcgacaaaga
      781 atttaaactg attgcgaagg actttcaaat acgtgcagct aaaacaggta tgctagcaga
      841 ttcaaagttg attgagacag ttgtaaaaaa ttaccaaaaa tatgattttg gaccattagt
      901 cgtggatccc gtaatcgtaa cgaaacatgg aaatctttta ctagaagaat ctgctttgca
      961 aagcttgaaa gaaaagcttg tccctttggc cgaagtactg acacctaatt tttatgaagc
     1021 agaaaagctg actggacgga cattagcagc tgaagaagat tttgtgcaag cagcaaaaga
     1081 actgcaagat atgggtgcaa aaaacgttat gatcaaagga catcatgcta aagatgcgca
     1141 gcaagaaaca gtcaatgact acgtattgct cgaatcagga aaatcatttt ggttaaatgc
     1201 accattttat cctaccgacc ggatcaacgg aactggcgat tcgctatctg catgtattgc
     1261 agctgagtta gcgaaaggaa aaacagttga acaagcgatc cgattggcaa aagactatgt
     1321 aaaccgtgca attcgtgaag aaataaatgt agggcacaaa tatggaccca tcaatcattg
     1381 ggcagctggt gaattagagt aaaagaaaga ggtcgtgagc ctgccgtcca gctccgagtc
     1441 acaaggaaca agttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg
     1501 aggagttggc aggagaacac cgtttgttcg gaagaaggga ctgtgacaag atttttgtca
     1561 cagtcccttt aatcttagta tatttttctc tacttgaata aaaaaattat aggattggag
     1621 aaaataatcg agaaatttgt tgcttgaata atagccagtt agacatttcc ttgactgttt
     1681 cagttgtcat ggatgaacaa tgtgtctcat cttctttgaa ctgagtagca agttcttcta
     1741 aaaactcagg atcgtaaatg acagcacttg tttcaaaatt caatcggtag ctacgaatat
     1801 cttgatttgc tgaacctacc atgcagattt catcatccat tatcaatgtt tttgcatgga
     1861 ggaagccgtt ctcatagaca aggatttgta cattttcctt gatcagctgc cgagcataat
     1921 attgtgttgc tcgataaata aaaggatgat ccggtttgtt gggaatcatg attttcacat
     1981 ctacaccaga ggcagttgcg atttttaaag cagcaatgac actttcatca ggaacaaggt
     2041 aaggtgtctg tatccaaaca cgttttttag cagaagtaat caatttgata aatgaaagct
     2101 tgatttgttc cctttcgtta ttcggtccgc ttgaaacaag ctggatggat gtatcagcaa
     2161 gcttagattc atctcgatct gcttttttaa agaaataatt caaatgatag ccgacctttt
     2221 tttcttcagg taccgagacg ttccagtctg ttaagaagcg aagctggagc aaagaagaag
     2281 cggcaccgaa aatccgtata tgcgtatcgc gccaatagcc gaattttttt gttgtattta
     2341 catattgatt ggcaatattg aaaccaccgg tataactaat ctttccatcg atcacaacga
     2401 tttttcggtg atcatggtaa ttcaatcgga aacgaagtaa tgccttttgt gaggtaacaa
     2461 atgtatggac atgtccacca tttttgatta gacgattgaa atcttttgct tttgtaccat
     2521 gagagccaaa tgcatcatat aatattcgaa cttccacgcc ttctgcggct ttttcttcta
     2581 aaacatgtaa gacttgctgg ccgatattat ctgtcacaaa tgcgtaatat tcgatatgga
     2641 tcgaatgttt ggcttttttt agatcttgaa gcagtgaatc caatttctct tgtccgtctg
     2701 tgagaagagt gacagaattc attcttgtca gcggcatacg atttaatgaa gagaagaagt
     2761 cgacaaattg ctgtttgtct ttatcgccca tgtcaggatc gtaatgttca atggtatctc
     2821 ctctaaaaga ctgaaagttt tctaattctt tcaagtcact ttgtcggaga tagaattttt
     2881 tcttatccgt taatccacgt ccgaaaaata aatataatac aaagcccacc ccaggaaggg
     2941 caaacaatac taagagccat gcccaaatgg ctgctacatc tcggggtttg atcaaaatag
     3001 ccaccaaagc aataagtgca tttaatagat aaagggcggt tataatacta gataccacaa
     3061 aaatgttcct ccttacatac aataacatta gtatagcatg atagaagaaa gaagcctacc
     3121 aaggtgaata tacttttcac tcctttcatg aaaatgtagg taaatcgggc taaagtagtt
     3181 gctttttgta ggttaataag gtaggatatt agtacagttg aatatctcct taggggagta
     3241 accggcaacg tttgttgcga taatatcaac agtaagttaa ccaaatggtt ttctggtatt
     3301 gtatgaaatg gtgagaccta agacaaatgc gtatttgtct taggtctctt tttttttcag
     3361 acaggactag ggccaagatc aaaaaatggg ggatgaaatt tggaaaacaa ggaacaagca
     3421 caacaagcgg tctataaaga aacgatcgac tcgttgatgc agcaaacgca gagctcaacc
     3481 gatggattga gcaccacgca agcgaaggaa aaattagaaa gagatggctt gaaccagcta
     3541 aaagaaaagc cgaagaagcc aacttggaaa ttgttcttag aaactttcaa agatgcaatg
     3601 gttatcgtat tgctgattgt cgcactgatt cagatggtca tgggtgacta catcgaattc
     3661 ttagttattt ttgcagtatt gatgttgaat tctataatca gtgttgtcca aacaaaaaaa
     3721 gcagaaggtt ctttagaagc gttgaaaaac ctttcagcgc ccgatgctcg agtgattcgt
     3781 gatggtaagg aaaaaacgat tccggcaaac gaacttgtgg taggagatat cgtgttgtta
     3841 gacgcaggcg attatgtacc tgctgatgga cgtttactag atgcgggatc attaaaagta
     3901 gatgaaggta tgctgacagg agagtcgact tctgcagaaa aagaagtaac ggatatcaca
     3961 agtacggtac caatcggaga tcgtacaaat atggtattca gtggaacgat cgtaacttac
     4021 ggacgcggta aattcttagt gacttcaact gggaataata cggagatcgg acaagttgct
     4081 ggccttttgg aatcaacaac tgagcaagtc actccgttac aacgaggtct ggataaattc
     4141 agtaaaaaac taagtctggc tattttggca ttgtctttat tgattttagg tatccaactg
     4201 tttcgtattt atcttggaga aggtacagga gatatgactg cagatatcgt cagcgcagtg
     4261 atgtttgccg tagccgtagc cgtagctgct attccagaag cattacagtc tatcgtaaca
     4321 atcgtgttat ctttgggaac gaataaaatg gcaaaacgtc atgccattat tcggaagctt
     4381 ccagcagttg aaacacttgg ttcgacaagt atcatctgta cagataagac tggtacattg
     4441 acacaaaaca aaatgacagt tgttgactac tttttaggta atggcgatac tggggatttc
     4501 acaaatgacc cttcaaaatg gacagctgac gaacgtcgct tgatcgaaat cagtgtttta
     4561 gcgaatgatg catcgatcag tgaagacggt actaaattgg gcgaccctac ggaagtagcg
     4621 tttatcgact ttagtgaaaa attaaaccag ccttatcagg aaatccgaaa caactaccca
     4681 agacaagcag aacttccttt cgattctgat cgaaaattaa tgtctactgg acacacgatc
     4741 gataacgaaa attacttgtt tgtcaaaggc ggaccagata tcgtcttcca acgcagtaaa
     4801 aaagtattgc taaatggtga agtcgttccg atgacggatg aattgatgaa aaaattccaa
     4861 gagcaaaatg aagctttttc aacacgcgca ttacgtgtac tagcttttgc ttaccgtcca
     4921 cttgataatt ttgatttatc atttgaagat gaagacgatt tgatccttgt tggtttgctt
     4981 gctatgatcg atcctccacg tgctgaagtg actcaggcgg taacagaagc aagaagtgca
     5041 ggaatcaaaa caatcatgat tactggtgac cacaaaacaa cagctgttgc tatcgcaaaa
     5101 caaatcggga tttttgaaga aggaaacctg gctttgaccg ggacggaact agatgaattg
     5161 acagaagatc aactaaacga agttttagaa aaagtcactg tttatgcacg tgtttcacct
     5221 gagaataaaa ttcgtatcgt tcgtgcttgg caaaataaag gtcatatctc agctatgaca
     5281 ggtgatggtg taaatgacgc accagcattg aaacaagcag acatcggaat tgctatggga
     5341 acgggtacag atgtggcaaa agatgcagca gcgatggtat tgacggatga taactttgct
     5401 tctattgtca gcgcagtaga agtaggacgt aatgtgtttg ataatatcaa gaaagctatt
     5461 tcttatctat ttgcaggaaa tttaggtgcg atcattgcga tcatctttgc cttagttgct
     5521 gactggtcca atccatttac agcattacaa ctgttgttca tcaatttagt caatgattca
     5581 ctgccagcaa ttgcattagg tacagaaaaa gctgaacctg ctacgatgaa ccgcccgcca
     5641 agagatccaa attcaggaat ctttacggac aaaacattga tttctgtaac gtatcgtggt
     5701 gtgctgattg ggattgctgt tatctttgct caatggcttg gcatgcagca ttcacctgaa
     5761 ttcggtgtag ccatgtcatt ttcaacattg atttggtgtc ggacattgca aacattccca
     5821 gcacgttcaa acacacaaac agctatccaa gcagggttct tctctaacag aagtgtctta
     5881 ctagctgtag ttgtatgtag cgcgctttac tgcttaacaa tgatcccagg actgaaagaa
     5941 gtcttctcta tcccatcagc atttggattg acagaagtct ttacatgtat gggaatcgca
     6001 cttgtgacaa ttgttttgat ggaaatcact aaattgatca ttgtacgagt acaaggaaat
     6061 aaataaaacg aatcaacgag gttgtgagcc tgccgtttaa ttctgagtca caaggtgcaa
     6121 tttcaacaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga agagttggca
     6181 ggagaacacc gtttaaggaa gaagttgtaa aatcagcatt ttgagctaat actgagggtc
     6241 atctgattgg acactgttta ttcggaaaga gggactttga cacgactttg gtcacagtcc
     6301 ctttttttat ttatgataga cggaaagcca atcattttat tattcatcaa aagagataga
     6361 atagataaaa gaggagaata atttattccg aaaagtgaaa acatataaca aaaaattaga
     6421 ggaaatcaaa tgaatgaaaa agaatgggat gaatttgctg aagaatatta tgaaatccag
     6481 caagaatcgc aagtaactat tgctgaagat gtaaaaaatt atctgaaaac ggagaaagtc
     6541 ctgcctgctg aaacagcagc agacgttgct ggaggatctg gcagatttct ttccttagca
     6601 aaagaaatta atcgctatga tttgatcgat ttttcttcag gaatgctaga aaatgcaaaa
     6661 aaagaagcag aaaaaaatga gttgccaaat gtttccttta tcaaacagtc gttagaagaa
     6721 tttatccaat caaatgagac atatgaaatg gtttttacag cagcaaatcc agcattggta
     6781 catcttattc aattagaaaa attgatgaaa aagtcaagca aatggtgcgt gataatcagg
     6841 gtagtggaat caatcgatga tgttttttat cctatcgaaa agcaactagg aatgatagaa
     6901 gaagatccta atacatcgcc agttgtaatg gatcaatttg aaacatactt aattgatgaa
     6961 ggattcaaag tgaagaaaaa agattttact tattttacac aggaatcaat tactgaagaa
     7021 ttgatgaagc tatactatga cgcgtacgca aaagatcctg ttgtgaccag gtacattcgc
     7081 aaactattca gtgaaaaacg agaaatcctt agtacgacta agctgaccta tagactgctc
     7141 ctttggtccg cagataaaaa aagaaccttt cacgactcgt gaagggttct ttttatgatt
     7201 ttattatatt ttgtagtaac gaatatcatt ttcgatcttt gtaatcgaaa aaggtacatc
     7261 tgaagtatat tctgcacatt ctccgtgttc aggaagcgtc tcactgaaaa tcgtttcata
     7321 ttcgtcaaca gtgatccgtg ttcgagaatc tagcatctct tgatgagatt gtgcgaagag
     7381 atattcttga tagttttctt ccagataacc tgtaaaaaat tcacttactg caccagaacc
     7441 gtagctgaat agaccgatgc gatctcctgg ctgtagtgat ttcgaatttt ccagtagaga
     7501 agttagcccc aggtataatg aaccagtgta aagattaccg attcgtcggc tgtaacggat
     7561 gctttcttca tagcgagcca taagacgttc ctgattttct tcgtctgttt ggtctaatac
     7621 gctttgcaat gccttttttc ccatcttagt atacggaata tggaaagcaa tcgcctgata
     7681 atcttcgagt cctcgacccg acaattcttt atgtcgattc caaacttttt ggaatgattc
     7741 gatatacgta gaattagata aaggaccatc aacaacagga aattcgctat aatctggacg
     7801 ccagaaatca tagatatctt ctgtcagaaa tacgctgtcg tcttcaatcg ataaaatacg
     7861 cgggttttga gtgatcatca tcgcaacagc accgacacct tgcgtcactt caccaccgct
     7921 tgccaagccg taacgagcaa tatcacttgc tatgactagt acttttcgtt ctggatgatt
     7981 tttgacatat tctttcgcca tgtgcaaagc tgcggtgcca ccgtagcaag cctcttttac
     8041 ttcaaaagaa cgagcaaaag attggatttt cagtaaatgg tggataatta ccgcactcgc
     8101 ttttgaatga tcaatcccgg attctgttcc gacgatgacc atgtcgatta gctcacggtc
     8161 tttttctgtt acgattttgc tggcagcatt tgctcctagt gtaatgatgt cttcatttgc
     8221 acgattgact gccatttggt cttgaccaat ccctatatgg tattttgcag gatcatcccc
     8281 acggctttct gccaactctg tcatatctaa atataaatta ggaataaaaa aggaaagacg
     8341 atcaatccct attttcattt caacacctct ttacttatga taaaaaactt actttactaa
     8401 ggtatcataa aaagattaaa agaaatataa aaaagagaat atttaaggat tgttaaaatt
     8461 taatcttaga aaaaaacaac tggaacaaga gctatttgtt tttacagcaa agaatggtat
     8521 atttttgtag gaggtggctt acttgaaaga agtcgttatg atagatgctg caagaacgcc
     8581 gataggaaag tatcgcggaa gtttaagtcc atttactgca gttgaattag gcacacttgt
     8641 gactaaagga ttattagata aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt
     8701 cggaaatgtc ctgcaagctg gtaatggtca aaatgttgcc agacagattg ctttgaacag
     8761 cggtctccct gtagatgtcc cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa
     8821 agcagtgatc ttagcacgcc agctgatcca attaggtgaa gcagaacttg tgatagccgg
     8881 cggaacagag agtatgtctc aagcacctat gctgaaaccg tatcagtcag aaacaaatga
     8941 atatggtgaa ccaatttcca gtatggtcaa cgacggattg actgacgcat tttcaaatgc
     9001 acatatggga ttaaccgcag agaaggttgc aacacaattt tctgtgagca gagaagaaca
     9061 ggatcgctat gccttgtcgt cccagttgaa agcagcacat gctgtcgaag ccggtgtatt
     9121 ttctgaggag atcatcccag tcaagatttc tgatgaagac gtgttatctg aggatgaagc
     9181 agttcgtgga aatagtacat tggaaaaact gggcacgtta cgtacagtat tctcagaaga
     9241 aggaactgta acagcaggaa atgcttcgcc attgaatgac ggtgcctctg tggtgatcct
     9301 tgcatccaaa gaatacgcag aaaataataa tctgccttat ttagcaacca tcaaagaagt
     9361 agcggaggtc ggtattgacc caagtatcat gggaatcgct ccaatcaaag ccattcaaaa
     9421 attgacagat agatcaggaa tgaatttatc aacaatcgat ctttttgaga tcaatgaagc
     9481 atttgcagct tcttctatcg tagttagcca agaactgcag ttagatgaag aaaaggtcaa
     9541 tatatatgga ggagcaatcg cattaggcca tccaattggt gcaagcggtg cacgtatctt
     9601 gactacatta gcttacggat tgcttcgtga acagaagaga tacggtattg cttcattatg
     9661 tattggtgga ggtttaggct tggcagtctt gttagaagcg aatatggagc aaacacataa
     9721 ggatgtgcaa aaaaaaaagt tttatcagct tacgccatct gaacggcgca gtcaattaat
     9781 agaaaaaaat gtattgacac aagaaactgc gttgattttt caggaacaaa cactttctga
     9841 agagctctcc gatcacatga tcgaaaacca agtgagtgaa gtggaaatcc caatgggcat
     9901 cgcgcagaat tttcaaatca atggtaagaa aaaatggatt ccgatggcaa cagaggaacc
     9961 atctgtcatt gcagctgcaa gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac
    10021 acctcagcgg ctgatgcgag ggcaaatcgt tctatcagga aaatcggagt atcaagcagt
    10081 gatcaatgca gttaatcatc gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc
    10141 ttcaatcgtg aaacgcgggg gcggtgttca agatatctct actcgggaat tcatggggag
    10201 tttccatgca tacttatcta ttgatttttt agtggatgta aaagatgcaa tgggcgctaa
    10261 catgatcaac tcgattcttg agagtgtggc aaacaagtta cgggagtggt tccctgaaga
    10321 agagattcta ttcagtattt taagtaattt tgctacagaa tcattggctt ctgcctgttg
    10381 tgaaatccca ttcgaacgct tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa
    10441 aatccaacag gcaggggaat atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa
    10501 agggatcatg aatggtatag aagctgtagt ggcagctaca ggaaatgata cacgtgcggt
    10561 tagcgcttcg attcacgcct acgcggcaag aaatggatta taccaaggat taacagactg
    10621 gcagatcaaa ggggataaac tagttggaaa actaacggtg cctttggctg ttgccacagt
    10681 aggcggagct tccaatatcc tgccaaaagc aaaagcatct ttagctatgt tagatattga
    10741 ttcagccaag gaactagcac aagtaattgc tgcagtaggg ttagctcaaa acctggctgc
    10801 tttgcgtgca ttagttacag aaggaatcca aaaaggccac atgggacttc aagctcgttc
    10861 attagcgatc tcaattgggg ctattggtga ggaaatcgag caagttgcga aaaaattacg
    10921 tgaagcagaa aagatgaacc agcagacagc tatacaaata ttggaaaaaa tccgggaaaa
    10981 ataaaaaagc aatatcttta gaagaataaa gcaagattta cagttatttt atttactgca
    11041 aatcttgctt ttttctctat cagaaaatat gtttattatt agaatttttt atagttaagg
    11101 ttaggcatct taagaaatca ggcaactcca agatatcttc aggtagaaga gaagtcgcct
    11161 aacattgtag gatcataggt gatttgttgg acaggtcaag ctgatatttg agcctgatgt
    11221 tagaaggaat ttctttttac ttgctgtaga aattattata tgactaaaaa ggctgggatt
    11281 ttaaatccca gccttttatg acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc
    11341 aaattgttcg atcaaaggaa tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt
    11401 ttcgataacg aactcatttt cagtagtcat agaaatagtt gctaatttac gaggttcatc
    11461 agcatttttt tcattaataa ctacttcatg ttcattttgt tctgtgtaaa atttaggata
    11521 ctcagcaacg gcttttgaaa aatcagcaaa acttaaagcg gcattcgtat cagttgagcg
    11581 tgtattttca gttgtgtccg cttttggttt ttccgttttt tcttctggca cactgactgt
    11641 ttcttctgta actggtgtcg caacagcttg cgcagttggt tcatcgtttt tcaatcgttg
    11701 atcattccag taagacacga tttcaataag aagattgtca cggaatcgtt cgaaaatccc
    11761 gttttctcct gaacgaattc tctttaatac agtattgaag ttgtcatcga ttggcacgtt
    11821 gatccgtgta tcttcatttg ttttcccagc taatccgatc gttaagattt gacggttttt
    11881 gggatcaagc atgacttgta acggcaaacc atagcgtcgc aagctctctt cttctagaga
    11941 acggaataat tgtcctctta caccatccaa tgaaggacgg aattgattta ataatttttg
    12001 tttctgtttt ttcttcatat gttctctcct tcgctcatac cctttcgatt ataagaaaaa
    12061 aacagccaaa tgaaaaggag taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa
    12121 aaatttgcgt attttcccgt tttttgaaag aaaaataaaa aatggaacgg attatgtata
    12181 tatacataat ccgttccatt ctttctattt tttcggtatc aaggcaaaaa caggtagttc
    12241 aggtgaataa atgacttcat gttcgtgcca gggtttgacc attagcgaat gatcgaaccg
    12301 ttttttcagt tcttcgatga tttgatcatg tgtccagttt cttgcaggaa aatgttggat
    12361 tttctctgca tcgatcaaaa agacaaaatc ggaatgaaaa gtctgggtaa cttcttccga
    12421 gagagaattc aagcgttcga ttggatccat aaaatcacct ttcgacttaa aattgggtag
    12481 tatctgggtc ttttgctttg ccgactacac catctaactg atcgatttgt ttcatttctt
    12541 cttctgttaa ttcaaaatca aataattcag tattttcttt gattctgctt ggtgtcactg
    12601 acttaggaag aggaaggaat tcgtgttgca gcgaccaacg caaagcaact tgtgcaatcg
    12661 tcttgtcatg tgcttcagcg atttgtttca tttcaggcac atcgaagatt ttaccagtgc
    12721 ctaatggact atatgcttcg aggatcatat catgtttttt tgcatactca actacagttg
    12781 gctgtaattc gcctggtgca aggaaaactt gattgaccat cggcataatt tttgctgttt
    12841 ttgctagtgt atctagatgg tggggtaaga aattgctcac accgattgct ttgattttac
    12901 ctgcttcata cagttcttca aatgctcgcc atgtatctgc atttgcttgt tcccaattat
    12961 cacgaaaagc aacagggttt ggccagtgga tcaaaaacag atctaaataa tctgtttgga
    13021 gcttcttcaa tgattcttca aaagaagaca tcacaagttc atagctgtgg tttgcattcc
    13081 ataattttgt tgtcaagaat atctcttctc taggaattcc actttcctta atcgcttggc
    13141 cgacactttc ttcattcttg tatccttggg cagtatcgat atggcgataa cctgcagcca
    13201 gcgcttcttt aacagaggaa acagcgacat ccccatcagg tgtttgccat gtgccgaatc
    13261 ctactaccgg gatttcgtaa ccatttaata gacgataagt gcttgttaat gaattcatac
    13321 tttcagctcc ttttttattc gttcaactat aagtgtagcg catttttcga aaaaaagaat
    13381 ccattttgtt tctactcttg aaatttttgt ttaaaagaaa atgattttga ttctggtatt
    13441 tttgattttt ttccgtaaac taagacagaa gggaatgaga aaatggatat ctatttaaaa
    13501 aaagcaattc tgcatattat tgacagagaa actggttctc cagtcttttc acaaaaagag
    13561 ctggatctga caaaagaata tattcgtgat tttcttcaaa agaagatcca aaaaatctct
    13621 tctgctcaaa caaaaactgg acaactagca gaagaaagca tgatcgttga atcacttaaa
    13681 atcgctcaag aaaattttgt ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc
    13741 taccaagaaa gtgaagaagc acctagtgca gatgtatttg ttgttttgta tgaattagat
    13801 acagtgatgt acttatcttt attgaaagtc aattatcgtg aggcttacac tcactttgtt
    13861 gaagcagacg aagcagggat cgacaaccgc ttgattttga atcgagcaat tctaggggcg
    13921 aaaacacaaa aagcagatga agcattcgct gtgaatttga ctgattggac ctacgaatta
    13981 attgaaaaaa aatatgagtt ttctggcaaa aaagagcttt atttttctgg aagagtgatc
    14041 gaaagtgttc ctgcaccttc tttagaagaa aatgtaaaag tgatccaaaa agtagccaag
    14101 catcttggaa aaaaatttga gacagaagaa tttgatatca tggctgattt gaaagaagct
    14161 gtctatgata cgatagaaga aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc
    14221 ttcaaggaaa acatcacggc aaaaatggct tttaaagaag aagtacaaga gcaaggattt
    14281 gtcccagaag cacctcctgt aaaagaagta caagaaattt ctgagaaaaa atttggaaaa
    14341 caaaaattca agctatcaaa cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac
    14401 ccagatttga ttgaatttgt gaataatccg gatggtacga tatccgtgat gatcaaaaat
    14461 gtggatgaag tattgaatcg tttataaaaa tgactagaac attaggtgtt caagtaccag
    14521 tgatcagtta aatgaattgt gtcaagagaa ggatcggaaa agacgaatat aacaa
//
LOCUS       DACGLI010000066        14062 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.068, whole genome shotgun sequence.
ACCESSION   DACGLI010000066 DACGLI010000000
VERSION     DACGLI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.068"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IXT22_002389"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IXT22_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAQ4863720.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IXT22_002390"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IXT22_002390"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAQ4863721.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="IXT22_002391"
     CDS             complement(2169..2906)
                     /locus_tag="IXT22_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4863722.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(3003..3524)
                     /locus_tag="IXT22_002392"
     CDS             complement(3003..3524)
                     /locus_tag="IXT22_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAQ4863723.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="IXT22_002393"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="IXT22_002393"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAQ4863724.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="IXT22_002394"
     CDS             complement(4401..4886)
                     /locus_tag="IXT22_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAQ4863725.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="IXT22_002395"
     CDS             complement(5039..5236)
                     /locus_tag="IXT22_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863726.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IXT22_002396"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IXT22_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAQ4863727.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IXT22_002397"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IXT22_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAQ4863728.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="IXT22_002398"
     CDS             9211..9423
                     /locus_tag="IXT22_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAQ4863729.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="IXT22_002399"
     CDS             9425..11104
                     /locus_tag="IXT22_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4863730.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="IXT22_002400"
     CDS             complement(11358..11558)
                     /locus_tag="IXT22_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4863731.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="IXT22_002401"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="IXT22_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(12249..12322)
                     /locus_tag="IXT22_002402"
     tRNA            complement(12249..12322)
                     /locus_tag="IXT22_002402"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12286..12288),aa:Ile,seq:cat)
     gene            complement(12634..13032)
                     /locus_tag="IXT22_002403"
     CDS             complement(12634..13032)
                     /locus_tag="IXT22_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863732.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
     gene            complement(13025..13477)
                     /locus_tag="IXT22_002404"
     CDS             complement(13025..13477)
                     /locus_tag="IXT22_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863733.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            complement(13464..13871)
                     /locus_tag="IXT22_002405"
     CDS             complement(13464..13871)
                     /locus_tag="IXT22_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863734.1"
                     /translation="MSFLLLKYLEIYSVKKNKLIGENDSPIKTPIELSLRNRMGILQR
                     SEIVKELFYHKFSYEIRLDDTYEHYRIVFFVYNSIEDATATTALTFGFTKNGTINSDK
                     TRQAATESDGICKKVCNGEENYWIGEEKLNEIY"
BASE COUNT         4152 a         2947 c         2365 g         4598 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagcaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc aacaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 cttcaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgatatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaattatg taccctgtag gactcgaacc tacgaccgga cggttatgag ccgtctgctc
    12301 tgaccaacta agctaagggt actggttgtt gccacataaa gccataaaca atcaaccagt
    12361 agaatgtgtg gcaacaaacc tgttatcgca tagcttggag tgtgactatt atgggtgata
    12421 gtgaagatat gcgataacat cactatttta tcgaatgatt tttatagttg tcaatacagt
    12481 catctaaata cttcatatca atcatttatt cagaaacaaa ctatcttgca ggatctatac
    12541 gagttaatta cagagcaaaa aagcctcaac caaggatgac tggttgaggt ctttgtcttg
    12601 caaatttaaa tagataactc tattacttgt attttatttt tgttgactat atagctgata
    12661 taaatcaata actgtaggca taactcctac ttcgctatat aaattagaaa tcaaattaga
    12721 agctttattc aggataggtt tagctagctc tcccatagat tcttctacta attttttata
    12781 tggctgttca tttgtagaaa cacgaataac tgaaaagagt aaaatatcta ccggtgctcc
    12841 ttccatcccc cctacaatgt gagctcgtaa agaaacaagt tttttttcta gatactctgc
    12901 ttcgtcttct ttatatccaa gttcaatatt aaactctaaa tctccataac taaaattatc
    12961 agttaattca aaatgaattt tattcaaact aatattttca agtgcaaaag taacactatt
    13021 tcctttatcc atgtacatat acctcttttt ctacaatata gcggctcgta tcttggtaat
    13081 taacactagc atagaccata tttgacgata cttcttttct ctttctactt ttaaatactg
    13141 agtaactttt attccgaata taaggtttat tttcaatacg gtcatattta atagggccgc
    13201 cagcaacctt aatagtgaaa ttcattgaat ctttatagga caaattttca acttgtttca
    13261 aaagtttatt gtactctgca acaggaatat gcatatctcc gaactcaaat tcaagatatt
    13321 ttttttcact tattcctaac atttttgaga attctgtcac gtttttttgt ttttttaatc
    13381 ttattttaag taattgtttg gacaggtttc tttgttcaga atttaatttt ttatataaat
    13441 caggatgttt ttttaataaa tcattaatag atttcattca acttttcctc ccctatccag
    13501 taattctctt ccccattgca tactttctta catataccat cactttctgt agcagcttga
    13561 cgggttttat ccgaattgat tgttccattt ttcgtaaaac cgaatgttaa tgcagtagtc
    13621 gcagtagcat cttctataga attgtatacg aaaaaaacaa ttctataatg ctcataagta
    13681 tcatctagtc ttatttcata actaaattta tgataaaaaa gttcttttac tatttccgat
    13741 ctttggagta ttcccatccg atttcttaag cttagctcaa taggtgtttt tattggagaa
    13801 tcattttcac caattaattt atttttttta acagagtaaa tttcaagata ttttaataga
    13861 aggaaagaca caattatggt ttaaatttga tccttcgaat agatttatca aagattttta
    13921 taaggtgtgg gattcagaag ttttctttct agcaatcgaa gatagcttat taatcaatct
    13981 ctactattct aataagaact actttaaaat ccctgctgca aaaactagaa tgaagaaaga
    14041 tgtatacttt ttgtttgata tc
//
LOCUS       DACGLI010000067        13863 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.069, whole genome shotgun sequence.
ACCESSION   DACGLI010000067 DACGLI010000000
VERSION     DACGLI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.069"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="IXT22_002406"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="IXT22_002406"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAQ4863735.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="IXT22_002407"
     CDS             complement(2260..2511)
                     /locus_tag="IXT22_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAQ4863736.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="IXT22_002408"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="IXT22_002408"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAQ4863737.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="IXT22_002409"
     CDS             3461..3679
                     /locus_tag="IXT22_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863738.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="IXT22_002410"
     CDS             complement(3968..4480)
                     /locus_tag="IXT22_002410"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAQ4863739.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="IXT22_002411"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="IXT22_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAQ4863740.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7367)
                     /locus_tag="IXT22_002412"
     CDS             complement(6933..7367)
                     /locus_tag="IXT22_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAQ4863741.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="IXT22_002413"
     CDS             complement(7377..8165)
                     /locus_tag="IXT22_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4863742.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="IXT22_002414"
     CDS             complement(8162..9103)
                     /locus_tag="IXT22_002414"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAQ4863743.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="IXT22_002415"
     CDS             complement(9280..9867)
                     /locus_tag="IXT22_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAQ4863744.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="IXT22_002416"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="IXT22_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAQ4863745.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="IXT22_002417"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="IXT22_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4863746.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="IXT22_002418"
     CDS             complement(12784..13719)
                     /locus_tag="IXT22_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863747.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYEQVVQQFLSQYVH"
BASE COUNT         3834 a         3103 c         2443 g         4483 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctcatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaa
//
LOCUS       DACGLI010000068        13824 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.070, whole genome shotgun sequence.
ACCESSION   DACGLI010000068 DACGLI010000000
VERSION     DACGLI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13824
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.070"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            823..1296
                     /locus_tag="IXT22_002419"
     CDS             823..1296
                     /locus_tag="IXT22_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAQ4863748.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1305..1532
                     /locus_tag="IXT22_002420"
     CDS             1305..1532
                     /locus_tag="IXT22_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863749.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2168..2539
                     /locus_tag="IXT22_002421"
     CDS             2168..2539
                     /locus_tag="IXT22_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863750.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2795..3037)
                     /locus_tag="IXT22_002422"
     CDS             complement(2795..3037)
                     /locus_tag="IXT22_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4863751.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3069..3971)
                     /locus_tag="IXT22_002423"
     CDS             complement(3069..3971)
                     /locus_tag="IXT22_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4863752.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3984..4172)
                     /locus_tag="IXT22_002424"
     CDS             complement(3984..4172)
                     /locus_tag="IXT22_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4863753.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4186..4749)
                     /gene="amaP"
                     /locus_tag="IXT22_002425"
     CDS             complement(4186..4749)
                     /gene="amaP"
                     /locus_tag="IXT22_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4863754.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4787..5680)
                     /locus_tag="IXT22_002426"
     CDS             complement(4787..5680)
                     /locus_tag="IXT22_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4863755.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5758..6696)
                     /locus_tag="IXT22_002427"
     CDS             complement(5758..6696)
                     /locus_tag="IXT22_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4863756.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6730..7080)
                     /locus_tag="IXT22_002428"
     CDS             complement(6730..7080)
                     /locus_tag="IXT22_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4863757.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7113..8015)
                     /locus_tag="IXT22_002429"
     CDS             complement(7113..8015)
                     /locus_tag="IXT22_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4863758.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8008..8865)
                     /locus_tag="IXT22_002430"
     CDS             complement(8008..8865)
                     /locus_tag="IXT22_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4863759.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9199..10008
                     /locus_tag="IXT22_002431"
     CDS             9199..10008
                     /locus_tag="IXT22_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4863760.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10048..10545
                     /locus_tag="IXT22_002432"
     CDS             10048..10545
                     /locus_tag="IXT22_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4863761.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(10930..11003)
                     /locus_tag="IXT22_002433"
     tRNA            complement(10930..11003)
                     /locus_tag="IXT22_002433"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10967..10969),aa:Ile,seq:cat)
     gene            11190..11513
                     /locus_tag="IXT22_002434"
     CDS             11190..11513
                     /locus_tag="IXT22_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863762.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11677..11931
                     /locus_tag="IXT22_002435"
     CDS             11677..11931
                     /locus_tag="IXT22_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863763.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12001..12246
                     /locus_tag="IXT22_002436"
     CDS             12001..12246
                     /locus_tag="IXT22_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863764.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12322..12687
                     /locus_tag="IXT22_002437"
     CDS             12322..12687
                     /locus_tag="IXT22_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863765.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12748..13311)
                     /locus_tag="IXT22_002438"
     CDS             complement(12748..13311)
                     /locus_tag="IXT22_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863766.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         4047 a         2562 c         2295 g         4920 t
ORIGIN      
        1 gtatgtccta tgatgaaaag attgtactat tcattgatca taacgattgg ctatttgatt
       61 gtatcaaatc taggaaatat ggtatttggt atcagtaaag aattcagttg gactactaca
      121 ttatgggaat ctctattctt tttcatcttc gtatttttgt tacaaaatta tcgaaaaaaa
      181 taaacatgtg ccatctatct gttggcacat gttttaggat ttatggtact ttttattcgg
      241 caatccattt tatttttcta cttcttctta atacctctaa cacttttgat ttataaacta
      301 atccaatgca tctacttgcg cttattaagc tatttcagct agatagtacc accccatgcg
      361 tcaatgcttg attttccttt tgtataacat tgtataagca ataaaggaca aataagtggt
      421 gattacacca aaccattgaa taagaaaaat tctgatacgt aaataaacat gaacttgaaa
      481 aaattaatga atcggttagc tactacgtag ttgtcttttt tctcatacag ttctgttaac
      541 ttacacttct cttcgctaga taataaaaaa tcctccaact gtattgtcca atataatccc
      601 aggcatctaa actagcatta tagaagagac acacatagaa tctaaaataa ctggttttaa
      661 atgtttctta caatcaaaaa aagctgttaa atgcactcca caccttcata ctctatcatt
      721 ttttataaac gatatatttt tattgttttt cgataaaaaa tagttgtttt acaataatta
      781 ttctgctata ttttagctat caaagataaa agagggataa aaatgaaatt taaaacattg
      841 ctattaaaat ttgtcgtttt aggtataagt gccgtattta ttttgttcgg cgtacttttt
      901 tatactcaga tcgctacaag cgaaaaagga ttcaattttg attggcagac cacattattt
      961 gtttctgtca tttactttgc ccttctccta gggatcgtta ttgcttattt cttattgaaa
     1021 ctattgaaaa aaatcgaaga taaccaagct ttttccactc aaagcttaaa catactaaaa
     1081 aaaatcgaac gaaccatttt gtttattggt ttcgcctttt ttggcttact tcctaaattt
     1141 atgaaagtag cggatttaga cgatgctcca ggtttgatgt tggtaggaat cgctgtcgta
     1201 ttcattcctt ttgcagtata cacattaaca agcgtgctgg aaaaactgct tgaacatgcg
     1261 attttactta agacagatca tgatttgaca gtgtgaggtg cgacatggca attatcgtta
     1321 atttagatgt agtattagct caaaaaaaaa tgagtgtgac tgaattgagt gagaaagtgg
     1381 gcattacgat ggcaaacatc tctattctaa aaaatggaaa agcaaaagcc atccgttttt
     1441 ccactctcga aaaaatctgc caagttttgg agtgtcaacc aggtgatttg ttgacctata
     1501 aaaatgactc gaatactata ccagaagaat aaaataaagt agaacaaaca gtaaataaaa
     1561 aataatctga atgatagatg tgtgagactt ttagaagtta tttacgtcta ttattcagat
     1621 tttttatttc gattgaatac cgttttatct ataaataaga tatgtactga ctcatacaaa
     1681 gggggccttt tcttctccat gtactatcac ttttcctgat acaactggtt tcctgttacg
     1741 ttgtagttgg atctgctttt agtataatac tttattcatt ccaccagact gatagcagtt
     1801 tgagcagtct aaataatcat gtagtattac aggccattct gtttcatacc ttgaagtgct
     1861 taaaacttca gctaatggcc cattgtgtta actcttactc cattcttttt tagtaagctc
     1921 ccatatatac tgtaaagcct tctatatatt atgtcatgtt gctttttaac atttactatg
     1981 tagttttgat aaaatgattt gaataacagt gatggacaat tcttttttat ttttaacatt
     2041 attttgataa taatgattat ttatttaaaa atacattgga taacatttgt tacgacacga
     2101 aaaagcttca caaacaaata tcgttatttt aaaatgaggg cgaactcaca caattaggag
     2161 gaatagtatg ccatttattg tttacttttt tctttcatta ctcgtgatct atattccatt
     2221 accaacattt ttcctgctcg tcaatcgtct agcagagcaa catgatacga ttgctgctct
     2281 tacgaaactt tgtttacttc tatttgtttg tctagattac tttacgagct attattggct
     2341 aaaacagaca agagtaaaaa agagatatta tttcttcctt gtctttttca atctctttga
     2401 gtttctgatc cattgctttt tacttcatca gtatcatacg atccatttgt ggatcatctg
     2461 ggttttcaaa gtggtcgtat tattttgtat gttcaccttt cctatctcaa gaaaatttag
     2521 ggaggcattg ttttattaaa gaagcttctc tgtatcaata aagacacatt taaggaaaaa
     2581 cttttaaaaa tctaattggg aatttgcccg cataaataag aggctgtgac aaaagtcttg
     2641 tcacagcctc ttattccgta taaacagtgt tcaaaagctt gcatcttcga taatatgccc
     2701 aaccaaatga aaaatatgag aagctatttt tgtttggctg ttcttattac ttgatgaaga
     2761 acagcttttt cacgacctct ttttaaaagt ctttttacag ttttcgagca aagaatgata
     2821 cgattagtac taaaatgatg gcaccaatca atgatggcac gattgccatt cctgcaatac
     2881 ttggtcccca agaacctaat aatgcttgac caagtgctga tccaactaaa cctgctacga
     2941 catttgcaat aatccccatc gaagaacctt tattcgtgat tgctcctgca attgctccga
     3001 taattcctcc gacgataagt gaccaaataa atcccatgtt tcgttcctcc taatgtttta
     3061 cttccttatt actgaacccg tggttctgta ttttctttta ctttttgtgc gccgcttcca
     3121 gctgctgatt ttactttatc tgtttgattc gaagcaaatt caccggtttt tttcgctgcg
     3181 tcagttactt tgtcttgcac cgtttcttga tctttttcaa attcttcttt tgttttgatg
     3241 tccactacgt tagcgttgac ttcgatcact tctaaatgtg tcatattttt tacttctttg
     3301 ccgattactt cttgcatttc ttcaaagatt ttttcgatat ctttgccata ttccacaatg
     3361 acatccatat caactgctac ttgtttttta ccgacttctg tttcgatccc agccgttaca
     3421 ttatctgtat tcacaagttt tcctgccaca ttagagaaga aaccaccgtt tgcagataat
     3481 aaaccgtcta cttgttcaat tgcgattccg atgatttttt gcacaacttt atcttcataa
     3541 ttcagctcac cgcgcattga atcttcctgt tcagaatcat gctttccttg gttatttgta
     3601 tgatcagaac caagttttcc ttgtccgttt gtgtggtcag aactaagttt ttcttgtgct
     3661 ttcgcatggt cagaaggatg tttttgctct tccacaggtt tagaaggatc gattgcatca
     3721 tgttgttctg gaactttaga ttctggagtt cctggatgat gaggtgcatg cttttctgca
     3781 tcatgtttct tctcttctac tccttgttga acgttaggga ctactggatc tggatgtgca
     3841 gatactggtg ctgttttgtt cttttcatcg ttcacaccat ttgattggtt tggtgtcgtt
     3901 gggtctggat gtgcagacac tggtttttgg ttgttcattt tattgttatt atttttgtta
     3961 ttgttattca tggatgtttc ctcctaagat ttaaaatagt gatctaagat tttcgtttgt
     4021 ttcagataaa aaccgatagc gacgccgatc gctgccatga tcaagatcaa taaggtcttg
     4081 aaaaagccca cggtgatcca taaaacggct aatatcaatc caagtacccc aaagatgata
     4141 gggagcttgt atgtcgaaaa tagttctttc atttttggtc cccccctatt ctactcgttt
     4201 gcggtcattg cttcgtttag ctggttcttc aaagcctgtg tatttcaccg atactttcac
     4261 tggctctttt gttcccaata tgtgttgtac ttcattttcg atttctttca tcaatgttcc
     4321 tgttttacca atgagtgctg aagttcgttt caactcccct tttacattga cggcgatctt
     4381 gtttttcgtt gctttgacat ttacttttgg tgaatggatg aattcatctt catgcaagtg
     4441 agaacgaacc attccttcaa ttgctttttt atccaacgtc aactccccat caccatgttt
     4501 cagtagaaag tttccgattg tttttggata aaacaggaaa acaagtaacg tgataattgt
     4561 caaaatagca aatgcaacgg caagccaaaa tacatattgt tgcacgtatg aattagtgat
     4621 ggaaaagaat cgaaacttct ctagctgaaa aggcaatgga taggttgcac ttaatagtat
     4681 cgcaaacaaa agcacagata gcaaaagtaa tgttccgatc actccgatcg tttttacacc
     4741 tttattcatt ttcgcacctc ctcatagggg tgaaacgatc aacttcttat aagttgatcg
     4801 cttctccacc agttactccg taaatttggg ctgtaacata acttgcttta ttcgatgcta
     4861 agaaaacata aactggtgct aattctcctg gctgacctgc acgttctagt aaactttgct
     4921 gaccaaattc agggatcgaa tcagaaggtt gtccttcgtc tagttgtaat ggtgtccaga
     4981 ttggaccagg tgctacacca tttacacgga ttcctttagg tgcaagctgt tttgctaaac
     5041 cgatcgtaaa gttagcgatt gaagcttttg ttgctgcgta atctaataaa tgttcgcttg
     5101 gattgaatgc ttgaacagaa gttgttgtta cgattgctcc tcctgctggg atatgcggaa
     5161 cagcttcttt cactaaagca aacatagcga tgatgtttat cataaatgtg tctttgactt
     5221 gctcaagtgg taactcagca atagactgac aagaaatttg ctgtcctgcg tttagtacca
     5281 tcgtatctag cccgccaagt tcactcacgg ctttatctat gatttcttta ggtgcttgtt
     5341 cgtcacgaag atcaaaaggt agtaagacaa tcttacgtcc tgcaactttc acgtattttg
     5401 ctacttcctc tgcatctttt tcttctcctg ggaagaattg aagagcgata tctgcccctt
     5461 ctctagcaaa tgcaatcgct gctgcacgac cgatccctga atctccacca gtgattagta
     5521 cacggcggtt ttctagttga ttattgcctt cataggattc ttctccacaa tcaggaacag
     5581 gaatcatatt ctgctgtaaa gctggtgtat cctgatcttg tttaggaaat ttctccgtat
     5641 ggtacaagtt tcgcgggtcg attaattttg gttctgtcat tgctgtattc ctcctagttt
     5701 ttaaattgta ttgccaaaac aaatttcttt gtttgatacc tgttttaaat agattcttta
     5761 atttgtataa tctttccggt ataaatggta acctaaaact actgctgcta tcaaagagcc
     5821 aaagactacg agtataaagc ctagagcaga acttttaccc ggtaatcctc ctgtattcat
     5881 tccccaaatc cctgcgaaca acgccggaac ggaaatgatt aatgcagctg aatctagata
     5941 tttcatgata tgatttagat tattgtccat catcccgttg aatagatcac caatactctc
     6001 taataaatct cgatagatct cgatcatttt ttctgtttgt cgctgtctca aatggacatc
     6061 atagagtagc tgttcatcgt ctaaacgttt gatgaaagtt tcagaattcc ataattgatc
     6121 cattgtttcc cgttgatctc ttaaggtatg atcgatatat acgatgtctc tttcaagatc
     6181 tgcctgttta tacagttctt cattttccgt tgttttacga gctgctttat ccaaagcgtc
     6241 aattcgcttt ttcatctctc ttagttcttt cacgtaatgg gtgtaaatat ctaataatgt
     6301 atacgtgatg atcttttcaa acgagtttaa atgatttcca tgctttgtca gcagccgatc
     6361 cacaaattcg gtttttctat cgatacaagt aatcaagaga ttatcggaaa gtacaaaaga
     6421 tattggcgtt aatttttttt cgatacgatt atctgactga tctagattaa tcactaccaa
     6481 agaaaatgga tgctctagtt tcgtctcata aaggcgctcc atccgagaaa cttcttccgg
     6541 atattcggtt cctacgaaaa tatcatcagg aagctcgaat tcttcgattg cttgctcaat
     6601 ctcttcgggc tttgcactat caagtacgag ccaattatat tttttttcat ctgtttctat
     6661 tacattcttt tcttcatcca caaagtagta tctcaatgta tacctccttt ttggactttc
     6721 tcgaaactat tagctgaaga agcagttctt taatttgata ttataatcga gtactgcgat
     6781 ttcattttct aatgaaaagc tgtcaagctg tttgttgaag tccatgttca atcgtttacc
     6841 gaaataattt tgctctaatt tagatgtata gatgtccaat aatggatgct cgattttagt
     6901 cgcatattct ccaaattccg aaacaaaagg aatgatttga aaaaagctgc cttttgcaaa
     6961 agcacctttg tcccttagaa atggatcgga atcattgata agcgcgagtg cgatttttgt
     7021 attttcccca accttttcaa ttaacgtctc tactgcattt ttagacattg taatttccat
     7081 tcctactccc cctcttcagt tgttgtcttc tattatttaa caactacatc tgtttttggt
     7141 tgaacttttg catattttgg atatttaggg aatttagcta cacaacggaa agccgtcatc
     7201 cctgcatatt tttcgtaata tttcttcgtt ggcccttcaa aatccttgct ccacggtttc
     7261 acatgtcctg aaaaatggat aatgtaagga ttgttgcgag tttcttcgta ttcacgttca
     7321 cctgctgctg ttggatgttt ttttgctttt gccatgatat agccttgtgc attccaacgc
     7381 ggatgaagtg gtaaccaacg gtcatgtaag atagcattta atgcatcttg gtcatggaat
     7441 cgtaattttt ctggattatg ttcgatgaaa tctaatactt tttgcgtaat attttcatct
     7501 aaccattttt tcacattgat cagcatcaaa cctgagttga aataacgcat tgatttagct
     7561 gaaattttca ttttttccag tcgttgatgg aacccagcgt cttcaacagc tgctacgatt
     7621 gaatcaccga agtcaagacg ccataattta gagatatctt gtaaagcgat catgtcgcaa
     7681 tccatatata agatacgttc aacttctgtg ccgcggaaca attccggaat cgcaatacga
     7741 taataagctg tttctggaat acgatcgctg attaccacat ttgtaaagaa ttctttattg
     7801 attttcaaga attccacatc tgagttcatt cgtgcgtttt tcactgagaa gcgtaaaagc
     7861 tgtttacttt caaaatcgat atcatcgtca atcacataga accgaacaaa tttagacggg
     7921 ttgcaattat ctaatactga gacaaataat gcagctaaat gtggtacgaa ttttgtgtta
     7981 caacttgcga ctactgctat ttctttttta ttcattgatc tcgcctactt tcgttagagt
     8041 actgtgtgct aattttttta agtataaatt ggtatacgga tgatctttca acgtattcca
     8101 aggtttatca tgtcctgtaa agtgaacgat cgaaggtttt tcatttcctt ctttatactg
     8161 acgttcatat ttttcatttg gtgctggatg acgttcaaaa atcagcgaag tctgcatgtt
     8221 ccattttgga tgaagttgtt cccaatcttc ataaagtaca gcattcaaag catcttggtc
     8281 gtgatagatg attcgatcgc cattttcact gaggtaatgg atagtttttt ctgtaatttc
     8341 ttttttattc cattgatcaa tgtcaatcac catcactcct gaattgaagt acaagtcatc
     8401 ggaatcgatt cctaatcttt ccaaagcttt cacttggcct ggatcgataa tagcgccgat
     8461 tgtttttcca tttaacggct catcatatag ttttacgata tcgtctagta ctaacacatc
     8521 tgaatctaag taaaggactt tcttataatc ctctttagct aataagtttg gtaaagaaat
     8581 tcttaagtaa gcggtagttg tgatatggtc actgactagg aagtcttcgt agatatcttt
     8641 ttccactgtc aggaattgga tacttgcatt acttgaatat ttatttaccg tttcttccaa
     8701 tccttcttta ctatattctg atagaccatc gtcaatcaca taaaatttta tgcgtcttgt
     8761 tttattgcaa ttttctaatg cagttgcgat catcacgctc aagtaaggag cataattttc
     8821 gtctgaagca gttaccacag gaactacgcc gtatctcttc tccatcaaaa tcactccttt
     8881 ttctaatctt tttctaacct gttctacatc tagaatattc ctcatttggt tttaaagcaa
     8941 aatatatgct ttgttttcat tgaatatttt aaaatttttt tatcacaaaa cgcatcggta
     9001 agcgctaact attcgttttt catggctttt tattcaaagg tattgaccaa aaactactat
     9061 atatagccac ctttttctta agaatgtttt ttgaaaaaat tcataatgac aaagcaagtt
     9121 agtttcattt ttttaaattc tcatttaatc ttaaggtaac aggaaaatag atatgtaaaa
     9181 agaaagtagg aagataaaat gaaactagca gcgattgatt tagacggtac cttgcttgat
     9241 cgaaatggaa agataccaga agaaaatatc caagcacttc ggaaatttga tgaaaatggc
     9301 ggaatcgtaa ccgtcgctac cggaaggaac agcatttctg ctaaagatat tttttccgaa
     9361 ttaggaatcg gtggctattt gatttcttcc aatggttcac tgattgctga aatgaaggat
     9421 ggaaaaatgg cgaaagttct cagacgttca aaaatagata gcgatacact gagaaaagcc
     9481 ttcttctatg ctcaagaagc gaaaatatcc atcattgcta gccgagaaac ccaagatgat
     9541 cagctgacat tcgatgaatc aaatctagtc aaagatgacc cttattatga acatttcaat
     9601 ttacagaacc attcttttga tcaaatttta aatatgttgg aagatccttc tcttagctat
     9661 cttaaattag cattaacaga taagagtgaa gaaaaactac agaagctaca aagagatctg
     9721 caagcagatg gtatccaatc agtattctct gatccgcatt tcttagaaat cacgcctaca
     9781 ggtatcacta aagctcattc acttgttttt ctggcggatt accttggaat cgaatcgagt
     9841 gacatcatgg cttttggcga tcaagaaaac gacattgcta tgttgaatta cagcgggttg
     9901 agtattgcga tggggaatgc acagcgacaa gtaaaagaaa ttgcaaacca agtaacactg
     9961 acgaatgaag aagctggtgt tgcttatatt ttaaaaaact tctattaaaa agaataaaat
    10021 gacgatatga atgtaggagg aaagaaaatg ttagttatta ttgatatgca aaatcatatt
    10081 cttgatccaa acagcgaatt ttatattcca gagtcagatc aattggcaga acgtattgct
    10141 caaagattag ctaaagcacg ccaaaataat gaatatattc tcttcacacg ggatatacca
    10201 gttgaactga aggacaaaga agaagaacga gaagatttgc aattgatccc tcttctttct
    10261 ccacaagaaa atgaacgagt gattaaaaag tattacttta cgattccacc tgaaacttta
    10321 gctgaaatcc aggaaacttt atttgaaagc aaagaagaac aaaaagagat cgaagtagtc
    10381 gggattgaaa caaacttgtg tgtactctct aatctgatag gcctgcagag tgcttttcct
    10441 gaagcagact tttttgttga tccaatgtta gtctccagta gaaaacacgg agaatccgct
    10501 ttagagctgt tgaaagattt caacgtctct atcgtcgaat cataaaaata tctatcttca
    10561 tttacgatat ttaacacaca ataaaaaaag cacgcagaac tgttttagtc ctacgtgctt
    10621 tttctatcaa agtagattgg cttttttatg acacagagtg aaacggcagg ctcacgacct
    10681 ctttcttaaa tggtgttcaa tcagctgacc ctcggtatta gcttaacaaa cggcaaaata
    10741 tgaggaacta tttttccgtt tgttaagcta atactcaggt caaaacgctg atttcacaac
    10801 ctcttcctta aacggtattc aaaagcttgc atctgcagta ataagaacag ccaagtaaaa
    10861 acataagaag ctgtttttac ttggctgttc ttattacttg atgcagggca gctttttcac
    10921 aacctcttat gtaccttgta ggactcgaac ctacgaccgg acggttatga gccgtctgct
    10981 ctaaccaact gagctaaagg tacatcataa ataaaattta tttttgttac ttttcaacta
    11041 tagcacgaat gacaaactct cacaagtttc aaaatataag taaaataata ttgttattct
    11101 tatttctttt acttgtgtca taactatttt gttactttaa tttttatttg cttattttag
    11161 aaaaaatgtt attcttttat ttattctcaa tgttaggagt gattattttg ccatttattg
    11221 cgattttatt cgatttagtt gcggcagcag cttattttct ccaattaaat tatcaaacct
    11281 caggaattct gtttattgga atgatttttc aaggtgtgat tacccttttg cttcttgtca
    11341 tgatgctcag ctataaagga aaaagatatg cccgtattca aacaaaagta tttgttaaat
    11401 atgtttccat tcgctatggg atcatcattc tttccttttt agtgaatgcg atcgtcctct
    11461 ttttatatgt attgaattac ttagatatca atccattgat tttttctcga tagataagac
    11521 acattcagcg gaacagttcc tgcttatcag cagaaaactg ttctgctttt tcatttttca
    11581 ttgatctatt cttcttttat tttcctagca tttcatttgt gatgtatgca ataacatgtt
    11641 atcttttatt atatgaatcg ttgaggagtc cgttacatga ttacgttggt gagagttttg
    11701 ttttgggtgc ctgcggtcgc actggtcgca agtattgttt atcttatgaa ttggaacaaa
    11761 gaacggtttt atttagctat tttgactctt ccggctatct actttatgtg gaaagttttt
    11821 aattacaact actttgaacc cgatagtgtt tttatagaag aattatcagg actggttttg
    11881 tctttattga tcgtcattct ttatttgata cgtttaaata aaaaacattg agtactattg
    11941 attgcatgtg tagctttcta tagtcattat aactattcta ctataatgaa aggtgattaa
    12001 atgagtatcg aagaagctat tttactggat actttacgtt gtcgtctgaa tttcttaaga
    12061 actggccgat ctttatctca agtagctgtt tctagcgcgt taagtattcc tttattcaaa
    12121 tatcgtaagt acgaagaagg agaagaaatt ccaagcatca ttgaattaat ctatatcgct
    12181 gacttttacg atatttccgt tgattaccta attggtcgct cagaaacagc aagcaaactg
    12241 aagtgatttt ttccagcctt ggtgctggtt ttttcattta acgtctaagg ttaacaatct
    12301 atatataaag gagacatttc tatgcgatta tggcatgaaa aattgatttc aaagcttcct
    12361 cgtcaacagc ttttaggaca acatcgggaa tgctgtgcat taagaggaaa tggctgggga
    12421 aagaaacatg ctactgtgga ttatgttttt cactattctc cttatagatt attccaatat
    12481 catcagcttg tcatggatga aatggaaaaa cgtggttaca gcccagcacc agagtggaaa
    12541 aatcctatgt atcgtggcaa atcatgcgaa gcattttttg atttacctac tgtagagcgc
    12601 aacgtgccga tttatccgga acacgatgaa gtttatctag cagaatgttt agcaaatttg
    12661 gagcaaaaag gaatttatct tacctaatat aactagaaaa gccttctatc tcctcttact
    12721 tcattaaaaa gctttaacca tcttagatca agctaaaatg tcgtaagttt tagggttatc
    12781 ttcatcctca cgtgcaaaac taaaagcgta ctctagtttt ggttcatcgc caacttccct
    12841 agacataaat gaacatctcc tgacgtggtt taaaagtacc gcatcttcga cgtctgtata
    12901 cgatgcacag cacagattgc ttcttttgat ctttcttttg atttttctgt tgcttcttct
    12961 acaccttctt cgattactac atcgatgctt acaattgctt ctgcctaata ttcccatgca
    13021 tcgtcgattt aagcctctgt agtcactgtg atcgtttcca cattttaact cctctgtcgt
    13081 ggcttcagtt gattttgtga tcagttcagt tgctaagcca gagtcagaac aacctgccat
    13141 tgctagcgtt aatattgata gtaaaaatag tttttttatc ataaggttcc ccccctgaaa
    13201 atagactaaa ataataacgc tttctttttt tgttttcaga cgaaaattaa taatttctaa
    13261 atattcttta aaaaagctta taactattat gcctttttta atatataaca cagttatttt
    13321 taaaaataag aatgctaaat cactctacaa taacggcgaa agcacaaaaa ataaaaaaat
    13381 tattacgtta ttaaaaaaac agatgaaaga tcaggtttta ttagatctca ttctttcatc
    13441 acttgaaggg atttaatgaa ctactttttc ctctttgtcg tttttatata ttcgtattcc
    13501 ttcaaacagt aggatagcct ctttcaatgc ttgatatttg aactgtccgt tacttaaaaa
    13561 tttagatgtg ccgccctctt cctagaacat attctttttt actttttcat taattgacag
    13621 accaatcgaa cgaaactgta aatttcgata ggataatgat tggtcaaact cattcatttt
    13681 caagacatct cgattcatat tcaagatagg aatcttttta tcaacatcac tttattcgta
    13741 ttttcctcta ccataaaagc ttcacgctcc acaaaattgt tttatacact actattcagc
    13801 ccattcaacg accaatgaat tttt
//
LOCUS       DACGLI010000069        13697 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.071, whole genome shotgun sequence.
ACCESSION   DACGLI010000069 DACGLI010000000
VERSION     DACGLI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.071"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            8..730
                     /locus_tag="IXT22_002439"
     CDS             8..730
                     /locus_tag="IXT22_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4863767.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            788..2827
                     /locus_tag="IXT22_002440"
     CDS             788..2827
                     /locus_tag="IXT22_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAQ4863768.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLLAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2936..4087)
                     /locus_tag="IXT22_002441"
     CDS             complement(2936..4087)
                     /locus_tag="IXT22_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4863769.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4241..4771)
                     /locus_tag="IXT22_002442"
     CDS             complement(4241..4771)
                     /locus_tag="IXT22_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863770.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4870..5220)
                     /locus_tag="IXT22_002443"
     CDS             complement(4870..5220)
                     /locus_tag="IXT22_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAQ4863771.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="IXT22_002444"
     CDS             complement(5377..6906)
                     /gene="ahpF"
                     /locus_tag="IXT22_002444"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAQ4863772.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="IXT22_002445"
     CDS             complement(6916..7479)
                     /gene="ahpC"
                     /locus_tag="IXT22_002445"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAQ4863773.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7623..8285)
                     /locus_tag="IXT22_002446"
     CDS             complement(7623..8285)
                     /locus_tag="IXT22_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4863774.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8469..10115
                     /locus_tag="IXT22_002447"
     CDS             8469..10115
                     /locus_tag="IXT22_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4863775.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10106..11188
                     /gene="uxuA"
                     /locus_tag="IXT22_002448"
     CDS             10106..11188
                     /gene="uxuA"
                     /locus_tag="IXT22_002448"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4863776.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11296..12849)
                     /locus_tag="IXT22_002449"
     CDS             complement(11296..12849)
                     /locus_tag="IXT22_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4863777.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12997..>13697
                     /locus_tag="IXT22_002450"
     CDS             12997..>13697
                     /locus_tag="IXT22_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4863778.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDV"
BASE COUNT         4628 a         2534 c         2531 g         4004 t
ORIGIN      
        1 atctattttg ttactgctta cattagtagt tggctatttt tcgattgagt ttatccatgg
       61 attttcgtct gcaaaacaga gttcaactgt gaaaaaggta gagccgaaaa gtatccctac
      121 cacactaaat gtggctttga ttggttcaga tgctcgttcg aaagacgaaa acggtcgctc
      181 ggattcactt ctggttgcac aatacaacca gaaaacacaa caagcaaaac tgatctctat
      241 catgagagat tcatatgtcg atattccagg ttacggaatg aataagataa atgcagctta
      301 ctcttatggg ggagttgatt tattaaatca aacattaaag gaaaatttca aatttgaagc
      361 tccctattat gcaagtatca catttcaaga ttttatcgat tgcgttaatg aactgtttcc
      421 tggtggagtc aagatcgatg cagaaaaatc tctagattta gatggcgtat atataaacaa
      481 aggagagcaa gtgatggatg gtaatacttt actccagtat gctcgatttc gggaagacaa
      541 agaaggagac ttcgggagga tcagaaggca gcagcaagtg atcaaagcta tctctcagca
      601 gctgaaagac gtaacttcaa tattcaagct acccaaagcg gttgggaaat tacttggtag
      661 tatccaaacg aaccttccag aaagtgtgct tctggattgt ggtatggatt tcctcaaaga
      721 catatgttag aataaacagg tataaatagt gaaataaagg aatgacaagc aagagaagga
      781 ggaaaaaatg aaaagaagtg acaagcacgg caaaaatcga acaggcgctt atattgccgg
      841 cgcagtgatc ttaatagcag ctgcgggtgg cggttatttt tactaccagc actatcaaga
      901 aacccaagca gtagaagctg gagaaaagac agttgagcaa tttgtccaag ctttgaacaa
      961 gggagattat aacaaagctg cagaaatgac atcaaaaaag gcggcaaata aaagtgcatt
     1021 atctgaaaaa gagatcttag ataaatacca gaatatatac ggtgctgctg atgtcaaagg
     1081 acttcagata tcgaatctaa aagtagataa aaaagacgat tctacttaca gtttttcata
     1141 taaagcaaag atgaatacct cattaggtga attgaaagat ctttcttata aaggaacatt
     1201 agacagaaat gatggtcaaa ccacgatcaa ctggcaaccc aacttggttt ttccagaaat
     1261 ggaaggaaat gacaaagtaa gcctgaccac acaagaagca gcaagaggga atattataga
     1321 tcgaaatggt gaaccattag caacaacagg caaactaaaa caattaggag tcgttccaag
     1381 taaacttgga gatggaggcg aaaaaacagc caatatcaaa gcgattgctt cctccttcga
     1441 cttaacagaa gatgctatca atcaggcgat ttcacaaagc tgggtacaac ccgattactt
     1501 tgtcccattg aaaatcattg atggagcaac gccagaactt ccagctggag ctaccattca
     1561 agaagtagac ggcagatatt atcctttggg tgaagcagct gctcagctga ttggttacgt
     1621 gggagatatc acagcagaag atattgataa gaatccagaa ttaagcagta atggaaaaat
     1681 cggtcgctca ggtttggaga tggcttttga taaggatctt cgtgggacaa caggtgggaa
     1741 attaagcatt acagatgcag acggtgtaga gaaaaaagtt ctgatcgaac atgaagttca
     1801 aaatggcaaa gatatcaaat tgacaatcga tgcgaaggca caaaaaacag cttttgacag
     1861 tctaggagga aaagctggat caactgttgc gacaacgcca aaaaccggtg atcttcttgc
     1921 gcttgctagc tctccaagct atgatccaaa caaaatgaca aacgggatct cacaagaaga
     1981 ttacaaagct tatgaagaaa atcctgaaca tccattcatc agccgatttg cgacaggtta
     2041 tgctcctgga tctacgttta aaataattac agcagcaatc ggtctcgaca acggcactat
     2101 cgatccaaat gaagtgttga cgatcaacgg gcttaaatgg caaaaagaca gttcttgggg
     2161 atcttttcaa acaacgcgtg tcagtagtga tgtatcacaa gtagacttaa aaactgcttt
     2221 gatctattcc gataatatat atgcggcaca agaaacgttg aaaatgggtg agaaaaaatt
     2281 tcgtacaggc ttagataaat tcatttttgg tgaagacctt gatttgccaa ttagtatgaa
     2341 tccagcacaa atttctaatg aagatagctt taactcagat atcttgctag ctgatactgg
     2401 atatggacag ggcgaacttc taattaatcc tatccagcaa gcagcaatgt attctgtttt
     2461 taccaacaat ggcacacttg tctatcctaa attgattgca gataaagaga caaaagataa
     2521 gaagaatgtc atcagcgaaa cagcagtaca aacgatcgtg ccagatctga gagaagttgt
     2581 gcaagatgta aatggtacag cacattctct ttctgcttta gggattccgt tggcagcgaa
     2641 aactggtaca gcggaaatca aagaaaaaca ggatgtaaag gggcaagaga acagtttctt
     2701 gcttgctttc aatcttgata accaaggtta tatgatggtc agcatgttgg aaaataaaga
     2761 agatgatgat tcagcaacca aacgagcatc ggaactattg caatacctca accaaaatta
     2821 tcaataaaaa attgcttttt aagtacagta aaaggactgt ggcgttatcg tcacagtcct
     2881 tttttcaaat aaacggtttt cacgatgtct ctttcacaac ttctttttga tttactcaca
     2941 cttcataaac tttttttgta aaatatttga gaacaagtgg agaaataagt gtacttaata
     3001 aaatcacgat aactaaaggt gaatagtact gtggttcgat caattgactt tgctgtccaa
     3061 tttgtaaaat gatcaaagcc atttctccac gcgaaatcat accagcaccg accatcaatg
     3121 aactatgttg agaaaaaccg gcaatctgag caccaaaata acctccaagc aatttggtca
     3181 aaatcgctac aagcgtcaat atagaaataa agagtagttg ttcactaaag tcagaaaaat
     3241 caacttctaa tcctacactg acaaaaaata ctggtataaa tactgcatat cctaaagcct
     3301 ctacattgtg gtatacttct tctttaacct ttgtctgact gacagctatc ccagcaaaaa
     3361 aagcaccaat gacagagcta agcccaacaa gatccgctac gtaagacatt cctaaacaaa
     3421 taactagcga tacgatgata atagaagaat ttgcgtacac tttttctgca aatgaaagta
     3481 ggaaaggcgc aatccatttg actaataaga aaataaaaac aaaataaatt agctgttcaa
     3541 tcaaaacaag cggtaaagaa gcattgctag aagcttcccc cgttagaaaa gataggctga
     3601 aacttagaac taaaacgact aaaatgtcat ctaccacaga agcacccaaa attgttgatc
     3661 cttcttttgt attcactacg tttagttctt ttaatacttc tactgaaata ctgacagaag
     3721 ttgccgcaag aataatccca aagaaaatcg cttcatttcc cgaaacttgg aatgctttgc
     3781 ctgtcaacca gccaaaaaca accgggaaga tgatcccaag caaagcaacg aacataccag
     3841 gtcggaaata ttttttcaaa agagataaat cactttccag accagctaaa aacattaata
     3901 agatcacacc aatctccgaa aagtcatgga ctagaatatc aggtttgacc caattcaatc
     3961 cagcttggcc tagcaaaaca ccaacaagta attgtccaat cactgctggg atacctaatc
     4021 tccgcgagat atgtgagcca atcgttgttg aaatcaatat caggcataaa ataccaataa
     4081 attccattct catcattcct ttgtataaaa tatagcccga acttagcata acatacatta
     4141 ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa tccaaaagat ttttttggat
     4201 tgttggtttt tatacggtct attttaataa ctaaaaatga ttaacgtata gtcatttttc
     4261 ttattctgat gaaattgata atctcctgga tgcccatgaa aatcaaaata aagccgaata
     4321 tttggaatag aagcatcaaa cttttgaatg gattgaacaa taagacgaat ccgccaatca
     4381 acaacagaat actactataa acactccaac ttttagcttt tgtattcatg ctgaagaaca
     4441 actggaacaa gctgttgatg ataacagcta atccaagaag aatcggcagg atagaaacga
     4501 ttgcaggtgc aaaagcatag acgatcagag ctaagatcag gaaaaaaaga ccactgaaca
     4561 gaccgatact ccaagaacct gttttccttt taaaacggta agcctcaaaa agattcaaca
     4621 acccaagcaa aacaagatag gcggtgatca gataaccgat aaaatgaaaa acagcagaag
     4681 ggtttagcac aatcgcaatc ccagaaataa tataaacagc agctcttaat aaggcgtatt
     4741 tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa cctcctttga cttattttaa
     4801 cgtgaactag tcattttacc aaattaaatg ttacaaaatg agcgaaggag aagaatatct
     4861 ctggaaaaat caacttctga ggatcttttc catttttttg ccttttgcta gctcatcgat
     4921 cattttatct aaataacgaa tttctttcat caagttatcc tcgatgtctt ctactcgtac
     4981 accacaaaca acacctgtaa tcaaggaacg tgaaggattg gggacagggg cttccgcaaa
     5041 aaattgttcg aaagtcactt gtttttgtag ttgatattct agttctgttt gggaataacc
     5101 cgtcagccaa caaatgattt catctacttc ctcttttata cgatcttttc tctccgcttt
     5161 tgctacatac ataggataaa cgcttgcaaa acttgtcgta aaaatacgat tttgcgccat
     5221 aatcagtcac ctttcttttt ttcaaattat ttactactta tagtatataa gaaaaagaga
     5281 agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac aaaattcttg tcaccatcct
     5341 tttttccgct ctctgacttt ttacaatctt catagctcaa gtgcgcatca gataatcgaa
     5401 tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca atgatttgtt tgtatggact
     5461 atctgtacaa tcaccagctg cgaaaacgcc ggggatattc gttgcgccat ttttctcggt
     5521 cactatttca tttcttggat tcatttcgat cgttccatct agccaatccg tattagggag
     5581 taagccgact agaatgaata ctcctgaaac agctagtgta tgcatctcca tcgtacggcg
     5641 atcgatatag gagagagatt ctacctgatt cgtaccgctg atttctttcg tcgctgcatg
     5701 tttgataaca gtgacattcg caagagagac tagtttatcc tgtaagattt gatctgcttt
     5761 taattctggt aagaattcta gaacatatac atgttttgct aacccagcca aatcgattgc
     5821 tgcttcaaca ccagaattac caccaccgat aacagcaatc tcttttcctt taaataaagg
     5881 gccgtcacag tgtgggcaat aagcaattcc tttattttta aactcttttt cgcctggtac
     5941 attgatagaa cgccagtgcg cacctgtcgc gatgatggcg gtttttgctt taagtgatat
     6001 accgttagct aagccaatat taataaaatg ttgctcttta tttaaggaaa cggcctgttg
     6061 attcatcata atgtcgatag ggtaactacg cacatgactt tctacttgct gcatcaattt
     6121 tggaccttct gtgtaagagg taccaatcat attttcaatc cctagtgttt caacgacttg
     6181 tccgccgaaa gaatcagcga caagtcctgt acggattcct ttacgtgctg catagatagc
     6241 tgcactacta gctgctggtc caccgccaat tactaataca tcataaggtt ctttttcaaa
     6301 caactcttct tcaatcaaag ggccagtgat tttttcaaca atttgttcga tcgtcatgcg
     6361 tccgctacta aattcttctc catttaaaaa cacagttggc actgccatga tttttttatc
     6421 atcgatttct ttttggaaca tcccaccttc aatcatcgta tgagtaatat ttggatttaa
     6481 tacagctaat atattcaatg cctgtacaac gtcggggcaa ttatgacaag tcaagctaac
     6541 ataactgtca aaatgcaatg tttgtgttat ttttttgatt ttaagactca aagattcact
     6601 gattttcggt gcccgtccac taatttgtaa catagccagt aaaaaagagg aaaattcatg
     6661 accgaggggg ataccagcaa aaacgattcc actttctttg ccaactggat tgatagaaaa
     6721 actaggtgtg cgcatcgaat ctcttttttc ccaagagatt ttaggagaca tttctgctat
     6781 ttccttcgta aattcagcta gtttttgact attttcacta ttatccaaac taacagaaaa
     6841 aacaatagga gattcaatca gtgctaaata ttgttcgaga ttttgtttag tttctttgtc
     6901 taacatatcc accacctaaa tctttccaac aagatcaaaa cttggtttca atgtttcgcc
     6961 actttctttc cattttgccg gacaaacttc acctgggtgg gtacgtacat attgagcagc
     7021 gcgaatctta tcaatcagtg cactagcgtc acgaccgatt ccatctgcat tgatttccat
     7081 agcttgaacg attccgtctg gatcaataat aaatgttcct cgctgagcta atccttgctc
     7141 ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac ggatcaccga tcatcacgta
     7201 ttcgatttta ccgatagcat ctgatgtatc atgccatgct ttgtgagtaa agtgggtatc
     7261 ggtagagcaa gaaaagactt caacacctaa agatttcaat gtactgtatt gttcttgtaa
     7321 gtcttctaat tcagtaggac aaacaaaagt aaaatcagct ggatagaagc aaagaatact
     7381 ccagttcccc ataagatctt tttcactgac ttctaaaaat tctccttgat gataagcatg
     7441 tgcattaaat tcttcgattt ttttcccaat caatgacata gtaaaacctc caataataat
     7501 tatttattta taattattgt aatttagttg gagttgcaaa gtcaatggat attttgttat
     7561 ttaataaaga ttactcaaaa acgaaggtta attataaaaa tagaagaggt cgcaagaaaa
     7621 tgctactgct ggaaatactc gggataacgt tgagtaacag tttcctgttc tttcagcatc
     7681 atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg gttttttatc aactaaagcc
     7741 ttgagtaaat cataatgttg ttccatgatc gtttcccatg gaagcccctg aatggtcact
     7801 cgtaaccagc ggaaacgttc taaatgggta ttatggtcat ctaaccagtt ccaaacttct
     7861 tttcttcctg caatttcgaa acaagcttca tgaaataaat tatctgcacg gaaaaaagcg
     7921 cgttcgtcat ttattttgac tgctttttct tgttcttcta aaatcgtttc tagcactatt
     7981 cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga tttgctcttc caactgttct
     8041 cggacaaagc gagcattttc tgcagaaaca agattaattt tggaaacata cgtaccactt
     8101 tgaggtatcg tatacacgag ttcttgctga cgtagttgaa tcaatgcttc gcgaatggga
     8161 gtccggccga tagcaagatg ttcctccagt gccttttcag atattttcct tccaggttct
     8221 aagtcagcat agataatttg tttacgaatc gcttgataag cttgtgattg caagctgctt
     8281 ttcatcttta ttcctccaaa atcatttcta tgaacgtagt ataacagaag aggtctgaaa
     8341 aacaatctgg tatgtcacat taactagtaa atttgtataa atagtaaaat tttggttgac
     8401 atagcgattt ttattgtata aaattcactt gaatacaaaa actaatatgt tagtttagga
     8461 ggggaaaaat gattgattta aacaactgga ggaactttat ccctgaatta tctcaaaaag
     8521 aagtagaaat acctcatttt gaccgtgcat cattaagaga aaatggacaa aaaaatcctg
     8581 tctggatcca tttcggtggc ggaaatcttt atcgaggatt tcatgcagaa atcgctcaac
     8641 gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt ttgtgaaaca ttcgatgaag
     8701 aaataattga aagggcttac caagattttg atgatttgat tcttgaagtg gtcatgccaa
     8761 gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc tgacagtctg tattgtcatc
     8821 cagattgttc tgaacacttt gataagatga ttcgacactt tgaaaatcct agtttacaat
     8881 tagttacttt tgctattact gaaaaaggtt atcgattgaa agatacaaat aataaatata
     8941 taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa gccatcacat acaatgagta
     9001 ttcttgctgc gctactttat aaacgttttt tatctggagc ttggccgatt gcacttgtct
     9061 ctacagataa tttttcacaa aacggtagtc aattacgtac ttctttgcta acgatcgcaa
     9121 aagaatggca aaaggaaggt tatgtacaaa atacatttat ccaatactta tcgaatgaag
     9181 aaattgttgc gtttccatgg acgatgattg atcgtatcac cccgaatcct tccttgtcag
     9241 ttagcaaaat gttggcaaaa gagggctttt caaatatgtc gattttccaa accgcaaaag
     9301 gaaataatat tgctccattt gtcaatacag aggacatcca ttatttaatc atggaagatc
     9361 attttcccaa tggacgtccg aaattcgaaa aagctggggt attcttgact gatcgtgcaa
     9421 cggtagataa agcagatacg atgaaggtga cgacttgcct taatcctttg catacgtctt
     9481 tagctattat gggttgttta ctggggtata ggagcatagc tgaggagatg aaagatccag
     9541 atttatcgct gctagtttct gaaatcgggt acaatgaagg cctcccagtt gtggagtctc
     9601 caggtatcat tgatccaaag atctttctgg aagaagtaat tactgtgcgc ttttctaatc
     9661 caaatattcc tgatatgcct cagcgaatcg ccacggatac ctctcaaaag gtggcgattc
     9721 gttatggtga gacgattaaa aaatatatgg aaatagaagt taaagacccg cagacacttg
     9781 tattcatacc attgactctc gctgcttggc ttcgatacct tattggcatt gatgatcaag
     9841 gaaaaccatt catcccgagt ccagacccac tattgacaga ctttcagcat aagctttccg
     9901 atattcaact gggtacgcaa gatacatcac atattcatga gaaaatggct cctattttgt
     9961 caaataaaga aatttttggt gtagatcttt accaagcaga gcttggcaga aaaatagaag
    10021 aaatgttcat caagatggta gcaggaccga atgccgtacg aaaaacatta caggattact
    10081 tacaagaaca tggaggaaat ttatcatgga aatgactttt agatggtacg gatcacagga
    10141 agaaaagatt accttagatg aaatcagaca gattcctgcg gtcaaaggga ttgtaggcac
    10201 attgatggat ataccagtag gagaggtatg gcccagggag aggatcaaag aactaaaaga
    10261 agaaattgag tctcgtgggt taacactaaa agtaattgaa agcgtcaatg tgcatgatgc
    10321 cattaaaatt ggattacctt cccgtgagca gtatatcgaa aactataagc agacaatccg
    10381 aaacttggca gaatatggaa tagaagtcat ctgctataat tttatgcctg tatttgactg
    10441 ggtgaaatct gaccttgact accgcttaga agacggctca tccacgttag cttttatatc
    10501 tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc atcgaacatt ccagcaatga
    10561 atttgaattg ccgggatggg aacctgagcg cttagctcat atcaaatcct tgcttgaagc
    10621 ctatgcatca gtagacgaag aaaaacttcg agaaaatttt gcctattttc tccaatcaat
    10681 catcccaaca tgtgaagagg taggggtcaa aatggctgta catccagatg atccgccata
    10741 ctcgattttt ggattacctc gaatcgtaaa gaatcgagaa gatttagatt ggttgtgccg
    10801 catagtagac agcccttata acggaatcac tctttgtaca gggagtattg cagaagatcc
    10861 agaaaatgat gtatatggga ttttagcaga attttgtcaa agagatcgaa tcccatttgc
    10921 acatgttcga aatattaaat ttttagctaa tcgagatttc tatgaggcac cgcataaatc
    10981 cgaatacggt tcattagaca tgtaccgcat actaaaaaca atgtatgaca acggatttaa
    11041 cgaatacatc cgtcctgatc atggaagaat gatctggaat gagacaggaa gaccaggata
    11101 cggcttatat gatcgagcat taggtgctgt ttatctaaat ggattatggg aagcaatcga
    11161 aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg taattttatt atgtaaataa
    11221 gaaggatgtt caaattcttg atacataaat ccggaggttg ttaataagca ttcggattta
    11281 tgtatcttat ttggtctagg aagtaacttg attttctttt ttcgattgat ccatgagtgc
    11341 ttcttctttt aattcaaaga tatattctga gatcctcata atcacttttt tccagtcttc
    11401 tggtgtgatg attcctttta aaatatagat ttttttgata tgagaaggca attgtttcaa
    11461 agggcagtcg ctgataacga tgttgcagtt ctccataaaa tcattttgta ttttgatcga
    11521 ttcatttgaa aaaatttgtt ctatcttaac gatcagatct ttactgatat aaaaatcacg
    11581 cgtatagttc acaccaatca caattcgcgg ctgttttttg tagcgatcat acaaatgtac
    11641 taggtcttca accatccatt gcacattttc cttttctaaa ataactggta acaagtgttg
    11701 attttgttct ctgaaatcca tataaaattg ttcaatggcg gtttggactt ctttcaacac
    11761 gctatgttct tgataaagca tgaaagtagg aaggggcgta tttggttgat tgaagttaag
    11821 aaatccatta taaagtttat ttcgtgcgaa tgccaatgag taaagaatct tttctttttc
    11881 aggtataaac aaatcaaata cagtacaaaa ggactccacc atttctcttg aataaagaac
    11941 atgaggaacg tttgcttttt ttaaaagttt gtattgctcc aagcttgttt cttccgattc
    12001 gattttcgtg atagaaagtc gagctaaaat attcactaag atgcgttgtt cgcgacaaat
    12061 tggcagatta ggtcgcaaaa tatctacaga gggatcaata aaaaagtcaa tatattcata
    12121 ctctgtgaat tctttttgta cgtctttcac agaagttgca ggaaaattct ctttacatat
    12181 ttttaataga aaatataatt tatctatcat accgctattt agtcggtcaa gtacttcttt
    12241 tttaaaaaaa gtattcatca taaaagccac tacttgcgga tcttcatcat aaaattctgt
    12301 agcagtactt gaaaagatgt tccaataaat atctaatgct gcatattgaa tttgtacctc
    12361 ttttccagaa aaagactttc tgccattatt agaaaaggag atagacaaac cgtacaatgc
    12421 taaaaatgca ttaatctttt tcattttcgt atacaaataa gaggcactat agtttgtttg
    12481 ctgacttaaa ctgataatcg aatttgtctg acagctgaac aaagaagtca agatctgata
    12541 actgactgat tcgttgcagt atcttccaaa tagacgataa tagcagtaag ccggatcaat
    12601 tccttcaaaa ttcaacttta aaaaaggttt ttgcttatca atatgcagtt ctgttagatt
    12661 gagacgctca aagtcttgtt ctaattcttt gatgtatagt aaaaaatttg attcagacat
    12721 atggaaatga tctgctaaat attgtgtagt aataaagaaa cgatgttcag ataggaaaag
    12781 aaaaatatct aattttgtat tgcttttttt cttcaagaga aacgttttaa tcgcttcttg
    12841 agtttgcatg aaagaggctc ctttttactt aaattgttaa aacttgaaaa tattactgtt
    12901 tttttcataa atttagacaa aaaaacagta aacatatagg tagaatctct actatcttat
    12961 ttcttgcata caaaaaaatc aaggagtgag agagttatga gatattcaac catcttaata
    13021 tcaacatttg cagccttaag cttatcgctt actataaatc agacagtcca cacagaggag
    13081 atagaaacag ccaaatggac agaaaccaag tgggccaacg tcaatcgaat tacctttcag
    13141 gatgaatttt catccttcaa ttcaggagtc gcaaaattaa gaaaaggaca aacagcgacc
    13201 atcaaagcaa aaattgacta ttcaggagac ttagcaccta tactacaatc agctgttaca
    13261 tttgagaatg ttgatcccgc tttgtcgatt ggctatgacg agaacacttt gactatccaa
    13321 cacaagcaag cgatatttac cttcaccgtt acattaaatc aggacttgtt aaaaccagcg
    13381 ctttttactg tcaaggtatc agatggacta ccgaacgatc atcatcattt aacgccgtat
    13441 agtcagcggc agacaattga gcaagattca gctatcgact caggaggaga tcttgttgaa
    13501 gaaccaacag ataaaccaga aaatgaaaat aagccagaag taccgcctac agaaaatcca
    13561 gacggagaac agaaaccgga aatagaacct ggagaagaac ccgatacaga aactcaacca
    13621 gagccagaca atgaatcaaa acctgaaata acccctggag aaaaaccaga tgtagaccca
    13681 gaagaaaaac cagatgt
//
LOCUS       DACGLI010000070        13680 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.072, whole genome shotgun sequence.
ACCESSION   DACGLI010000070 DACGLI010000000
VERSION     DACGLI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.072"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(194..1324)
                     /locus_tag="IXT22_002451"
     CDS             complement(194..1324)
                     /locus_tag="IXT22_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4863779.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1865..2071)
                     /locus_tag="IXT22_002452"
     CDS             complement(1865..2071)
                     /locus_tag="IXT22_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863780.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2087..2701)
                     /locus_tag="IXT22_002453"
     CDS             complement(2087..2701)
                     /locus_tag="IXT22_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAQ4863781.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDKVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2848..3531)
                     /locus_tag="IXT22_002454"
     CDS             complement(2848..3531)
                     /locus_tag="IXT22_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4863782.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3640..4098)
                     /locus_tag="IXT22_002455"
     CDS             complement(3640..4098)
                     /locus_tag="IXT22_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAQ4863783.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4182..5945)
                     /locus_tag="IXT22_002456"
     CDS             complement(4182..5945)
                     /locus_tag="IXT22_002456"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAQ4863784.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6166..7626)
                     /locus_tag="IXT22_002457"
     CDS             complement(6166..7626)
                     /locus_tag="IXT22_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863785.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7834..8760)
                     /gene="glsA"
                     /locus_tag="IXT22_002458"
     CDS             complement(7834..8760)
                     /gene="glsA"
                     /locus_tag="IXT22_002458"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAQ4863786.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8783..10210)
                     /locus_tag="IXT22_002459"
     CDS             complement(8783..10210)
                     /locus_tag="IXT22_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4863787.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10241..11455)
                     /locus_tag="IXT22_002460"
     CDS             complement(10241..11455)
                     /locus_tag="IXT22_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAQ4863788.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11796..12038)
                     /locus_tag="IXT22_002461"
     CDS             complement(11796..12038)
                     /locus_tag="IXT22_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4863789.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(12070..12627)
                     /locus_tag="IXT22_002462"
     CDS             complement(12070..12627)
                     /locus_tag="IXT22_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4863790.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12640..12828)
                     /locus_tag="IXT22_002463"
     CDS             complement(12640..12828)
                     /locus_tag="IXT22_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4863791.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(12841..13407)
                     /gene="amaP"
                     /locus_tag="IXT22_002464"
     CDS             complement(12841..13407)
                     /gene="amaP"
                     /locus_tag="IXT22_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4863792.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4090 a         2823 c         2231 g         4536 t
ORIGIN      
        1 tatgcgtttt tttgttgatt taccaacatg tttagacatt ttcctctagg aaaaaattaa
       61 ctagcaccac gggtataata tgattttttg agatactttc attgcgaatt cctctttcta
      121 aaagaacctc tcgcttgaaa aataaaagat tgtactttat gataattcaa actgagagtt
      181 tctcagtttc tctttattgt ttttcaggtc gatagagcgc caactcttcg gcctgtatct
      241 ttgaagaaat attcaacgtg attccgattc ctaaagaaag gatcagataa cttgttcctc
      301 cgtagctaac aaatggcaat ggcacaccag tcattggcat cagccccgcg atacttccca
      361 cgttcattat cgtctgaacg aatagcaaag ttccgaatcc taaaagaaac aatccagctt
      421 gctgattttt acagcgactg cttaaacaaa agattctcat gcataatgag aacaataaga
      481 aaagcacaca caatgcaccg attagcccaa gctcttctgt aataatcgaa aaaataaaat
      541 ctgtttctgt ctctggaaga tacccttttt ttgtgatact atttcctaat ccccgcccaa
      601 atatgccacc attatatagt gcataaaacg aatgggtcat ttgatagccc gcaccatgac
      661 tatcgataaa agaatctctt aaagtcgcga tcctttcata agcatgatta aacatctgtg
      721 gaagccaacc tttatttcct aaatataata ccccgcctgc tgctccaatc agcaatgcag
      781 aaaaagtaac gattagatag atcccttttt taaatggaac cgccgctgcc caaaatatga
      841 cccacgcaat cgaaaggatc atcaatgctc cagcaatctt tggctgaaat aaaatcagaa
      901 aagttatacc tactgtaatc aggaatggtt tttttagatc ttttgggcta ctatttccgt
      961 cacgaaaaaa ccagcttaaa taaaaaatca aaaaaagatt tgccagttca gaaggctgga
     1021 attgaatgcc aaacagagag atccaacgtt gtgcgccgtt gacagtgaca ccgaatatcc
     1081 ctattcttac taatactaaa aagaaaatcg ataaggctaa accgtatcct gctattttag
     1141 ggtgaagtaa atagtgtagt ttgactgaac gagctaagaa gatcacgctc caactcaaaa
     1201 atatgaaaat tagttgacgc aataatagac tttttgtatt ttcatcggct tgcaataaac
     1261 gataagaact ggcactgtat acttctaaaa gaccgatcat ggacaaagtc aaataaggac
     1321 ccaaaatcca ccaatcgatc ttttttcacc gcatctcctc ctcacacagc aatccacttg
     1381 tcaggtgagg agcgagtttg tctcatcaaa taagtcagtc acaaaaatat aaagaaaagg
     1441 tcagaaacct tttcgaacaa gaattctgac ctagcatcat ctcatcgtcc gagttttagc
     1501 actatacaac gtaaagaaaa cattcttagc tattggaaaa agccttaatc caacagtttc
     1561 tgttttaccc attggcgact ttcgacgttt ctgggcaaca gcctatgttt gtataggagc
     1621 ctcacctaac aaggttatta ctatattcta tttacgagtt catgatagac ttttcctaat
     1681 gattaggcaa tggaatttga aatgaaatag tgaaatttaa caatctttaa tattttttag
     1741 aaaaaaataa caaataagtt gaaagaatcc cgttgcaaat tctttcagtt gcaccaggat
     1801 tctttgataa ttttttagtt ttatgtgttt ttttatatgt tttttcactt ttcggaataa
     1861 atatttattt gttaaagtaa ttaaacaatc cgctaatcgt ttgatctggc atttctattt
     1921 ccttaccatc taaagtaaca gtagtaacga caaaatggtc ttgcaatggc ggaacttcta
     1981 agtactgccc ttgcagaaaa tcattcactg tttcatattc ttttttcatt tcttttgaat
     2041 ctgtcgatgg tttatagctt atttttaaca taactagtgc tcctttttat tcgggacgtg
     2101 caatcgtgaa aatttctcct attgctgcat aatcatttcc tgccaaacgg cttacagcat
     2161 tcaattttct tggatcgatc cttcctgtct tatcatcata gactgtttca tttaaatgat
     2221 atttctgtac ttctagcaaa aataaatcag ctgttacttt atttttattc cgtatctcga
     2281 catgttcata taaggatgtt tcaaaacgaa cttttgcttc tgtcaatgct ggtactgaaa
     2341 tgattactga atcagttaaa gtcaagtcag tcaggtacag ttcgctttcc tcattaggca
     2401 gattggctgc tgttttattt acttcttcta ctttgtcctc atcaaggata tggataacag
     2461 cttctcttgt ctcaagaata ttctttgctg tgtcttttac tgcatcttgt tttctctgga
     2521 tcgccaagga taagatgggt cgattcgaac tgacgatatt gaagtaactg aagggtgcga
     2581 tattcactat atcttttgct gatttagtcg ttactactgc tactggtcta gggatgactg
     2641 aaccaatcag caacttgtaa ttttcacgtt ctgtcaattc tgaaggactc cgttcaaaca
     2701 tggtttcgcc ttctttctat aaaattcgtt aaaaagcaga tcttgaagac aaaatgaaaa
     2761 gtaatgcttt tttcatcttc ttagaatctg ctttaaacta tctatcaatt tttctttttt
     2821 gtcaagaatc tgtgccgtgc gtgtttttta gttatttgct ttacttgcgg cttcgacata
     2881 tcttttagtg atcaattgcg gacgggtgat aatagatcca actacgactg aaaaagcacc
     2941 taattcatat gctttctcta cttgttcagg agagtcagta tgtccttcca taattactgg
     3001 gatatcgact tgttctatga tttgattcaa taaatcaaaa tcaggtgtct gcgtctttcg
     3061 tgaatattct gtatagcctg ctaaagtcgt agacaaaaga tcaaaaccat cttcttgcgc
     3121 ttgaagcgct tcctcaaaag tcgaaatatc tgccatagct aaccgaccgt gttcgtgaat
     3181 catttggaca agttcagcag ttgttttttc tgtcggacgt ttacgagaag ttgcatccag
     3241 tgcaatgatt tctgcttgcg tctccaaaag ttcttccact tctttttctg tcgcagtaat
     3301 aaacacttct gacccatcgt aatctctttt gataatccct attaccggta aatcaacgat
     3361 tcgcttgatt tcattgatat cttctgtcgt atttgctcga ataccaactg ctccgccttc
     3421 ttttgcagcc aaagccattc tccccataat aaaagaactg tgtagcggct cgttttccaa
     3481 agcttgacaa gaaacgacga ctccgccttt gatttgttcc agtgtatcca caatatctcc
     3541 tccagtaatg ttatataaaa atacagcttc atataaaaat gtaacccttt tctattcagg
     3601 agacaataat gagctatttc tttcagcaga cctttcttac taaaagaaaa ttacttcaaa
     3661 ttcttcgtat acgaccagct tctcttctgt aaattctatg ttcaacgctt ctttataagc
     3721 atgtttaaaa aactcagcat ggactttccg ccaataagct aatgtccgat ccccttctcc
     3781 ttctttccaa gcatgctctt tcgtgacttc actaaaaggc aagatggtca catttatatt
     3841 tttgatgata caaactggtt cattttttcc attcaggacc acgtctaatt gaccaacttt
     3901 tggtaaaggc tcattctctt gtttatacag atcgtaacca cttgatgtac cagtctttat
     3961 cttttttaca actagttcgc tcaactcgtc tgccattttt tctgtatccc caaatgaaaa
     4021 gaaacctaat ttttctgatt gataactagg atatttttct tggaactttt tgacatattc
     4081 ttctacttgc tgatacataa catccacccc tttgcttttt ataatgaaaa aaccatccag
     4141 atactagtat aaacaattat ctggatggtg agcataatga attattgaat attcaagaca
     4201 cgcagactat cttcaacgat ttgttttggt gttaaatgat aacgttcata aagctgccct
     4261 acaggaacgc tatccgtgaa ttctttctct gcaccaaaat ttaatacgtt cattgaagaa
     4321 tcaccataat aacgactgat attttcgcca aatcctcctg acaaactacc atcttctaat
     4381 gtgatgacta attcgtgtgt ttcttttaat ttatctaatg tttctacgtc attttctgtg
     4441 atcgttcctg gattgatcaa cgttgcttcg attccttttt ttctaaaagc ttttactgtt
     4501 tcttttccta attcaagaaa accgcctaaa gctaaaattg ctacttttcc tccattattt
     4561 actgtttgat aggctggaat actataatca tttgcgatag ctgtaccatg ttctacacca
     4621 tgtgtaggaa ttcggattgc tacaggctgc gctgtttgtt cgaacgccca atctagcata
     4681 gagatcatat cctcttttgt tgctggagca agatatttga tgttcgggat acttgataag
     4741 taaggaatgt caaatgttcc ttggtgtgtt cggtcactag ctgagatcgt tccgccaccg
     4801 actaaaataa tcactggatt ctcgttgatc gctaaatcat gtgataattg atcatatgcc
     4861 cgttgcaaga aagtacttga ttggaagacg actggacgta ctccctgaga agccaaagca
     4921 gaagcgaaag tgatagagtg ctgttcagcg atccccacgt caaaataatg atctggatgt
     4981 ttttcttgga atgttttcag tccaaaggcg cctggtatcg ctgcattgac tgcggcaata
     5041 ggagctgtac ttgtttgcat tttcttatcc aaataatcca tgatgatcat attaaatgtt
     5101 tctccagaag ttacttgctt tgcctccccg gtggacagat caaatggtac atgccaatga
     5161 tatttcattt tattatcgat tgccggctga taaccgcgac ctttttccgt atggacgtga
     5221 agtacaatcg gatgatcaat atcttttact tcttcaaata aacggatcac cgtttccaga
     5281 tcgtttccat tatccacgta acgataatca aatcccattg ctttaaatag gttattgctg
     5341 cttttaccgt tggtttgacg aagctcagct aagtttttat ataaactgcc atgattctca
     5401 tcaatagaca tctcattatc gtttactaat acgattagat tggattgtaa aacaccacca
     5461 ttgttcaatc cttcaaaagc taagccacca cttagggagc cgtcaccgat aaatgctacc
     5521 acatttcctg attctttctt cagatctctc gctttagcta aacctgttgc taagctgata
     5581 gatgtagatg tgtgccccac tgtaaaatag tcatgtttac tttcatgttg gttggaatat
     5641 ccgctcactt cacggtaatg tcctttttca aaaccatttt ttcgaccagt taaaagctta
     5701 tgaccataag actgatggga aacatcccaa acgattttat cctttggtga atcaaataca
     5761 taatgaaacg caatcgttaa ttctactaca cctagattcg gaccaacgtg cccacctaca
     5821 tcgctgtcct tttgcaagat tttttggcgc atctcttctg ccaactgttt catttcctca
     5881 acagataatt ttttgacatc tgcggggcta ttgattgcat ccaatacatg taatactgta
     5941 ctcataatac attctctcct ccgtactatc ttcttttaat gaaaatagat ttgttacact
     6001 ttatctattc tactacttag agttgactct aagtcaatag cattttaaaa aaatttcaga
     6061 gaaagcttgt tatataagta gatcttcgca cgaatcagga ctcaaataaa aaccttctac
     6121 agacaattaa aaagctttgt agaaggtctc ctaattaagg tctcatcaag aaatatgttt
     6181 ttttaatagg tgaagttcct gagcaatatg atacaaatgg atgtttgcac cttttaatga
     6241 gattggatag atctttgtct tttcagtttc taatccattt tgatagctag cagcatcgca
     6301 caaaaccact ctttttttcg cacatagaca ttcatcaggc aattcttcta atgaacgaaa
     6361 taaaatagga tttatttcag cgatgccttc ttccgcatac aaatgaaatt gggttcgata
     6421 aaaaaattgt ttgactgaac tttctgaaac aacaaaaatt tctatttcct gtctccccgc
     6481 ttgttcactg ttgatcaaag aaagactttt gacgaatttt cgaatgaaat tttcattcca
     6541 tcttagttgg atttgatttt tctttttcca ctcttccaat atttctacaa tttttccgta
     6601 cagaagttgt tctttttctg atagaagata gatcctttcc ggtaaaaata cttgtccatc
     6661 tgcccacaac gtacggacaa attgtaaaaa ggattgcttg aaaataaaat tttctgcatc
     6721 gtcgatttca gcgatactaa taatctgtaa aatcaattca ttcagtgata ggtcattgag
     6781 aacaaaattt ttataaacaa cttcgaaatc ttttcttaac agctccatgt tctcattggt
     6841 ataatttcta ctgttgaaca aagaaaaaat ataatagaca tcttcttctt gtaagtctag
     6901 aattcctttt tgctcttcca atccttgaca gactaattga aataacggct tcgtttctgc
     6961 gcttttctta tcttcttctt tcagtccaag gggaaatgcc tttcttccga ttgcgatctc
     7021 tattcctcgt atgataaagg acttttcatc ttccgaatat cttcttttaa aaaaatgagt
     7081 ctctacataa tcaatcaact cgttacaagc ttcttctaca tacggatttt tattttcata
     7141 gccttcccaa ttgacataac gtactaaagc tagcaagatg ttccgcgagt caaattctgg
     7201 gataatgatt tctttatttt tcaaataatc attttcttta aaaaaatcca atacgatttt
     7261 tttgattgta tatactttgc tcaaagaaat aaattcaaga tcagccagtt ctgtactcgt
     7321 gaatatacca ttaaaataat aacttaaaaa ctttaaaaaa taagattgac cgtacagaaa
     7381 ctgtgtgagc tcagaaagag caataccatg tttgaatacg agtttatact tatgcttctc
     7441 tcttacttgt tcttttatac aatattctag acactcggct agactttcta gatcgtgaag
     7501 gatcgttggt gtagtcaccc ttagagaaat agctgtttgt tcgatgtcta tttcttggaa
     7561 ttcaaataat tgttcacaca gatacacttt tctaaatata tttcgctcga tgtaattttc
     7621 cagcattcct gatacacgcc tccagttttt cttatgattt tatttaatca tatctgtaaa
     7681 tcgtattttt gtttcctttt tatttagaaa agccctttca aaaaccaata aaaaaagaaa
     7741 ctgggacaaa agtcaaacaa gctcacaatt tcagcctcat tgtaggtagc tttgagccgt
     7801 ttggactttt accccagcct ctttcaagaa tggttattca aagatgtcag cgtctagttc
     7861 tttgactaca tctttcaaca attggatacc agctgcgctg ttaccaaatg gatctagtgc
     7921 cgggctgaag acacctatgc cgtaacgatt tggcacagct gccatcaacc cgccgcctac
     7981 accgcttttt gcaggtacac caacatggac ggaaaactct cctgattcat catacaaacc
     8041 agcagttgtc ataattgatt tgacgattgt agcactttct tcagtaatga tttgtttgcc
     8101 attccaagga gcaattcctt tatttgccag cacagcagct aattttgcta tgcctgtagc
     8161 ggtgacattg agggagcatt gtctgaaata agcatcgagt atctccggta cgtctccttc
     8221 gatcatttga ttacctttca tatagtaagc aagagagcga ttgatatcac ctgttcttga
     8281 ttcagaatga tagatttctt cattcaatgt gatattagga tcatcacaga tctctttcat
     8341 aaatgacaag attcgctcaa atttttcatc tgcatcttta ccggcaatca acgaggttgt
     8401 tgcaatcgct cctgcattaa caaaaggatt cattggatgt ttgcgatgat tgatttccat
     8461 attcatgata gaattgaagg caaaaccggt tggttccgtg ttgattgttt gaaagacttt
     8521 ttctattccg ttgtctttga ttgctaataa caatacggga acttttgaca tgctttcgat
     8581 ggcaaagcgc acatcggcgt ctcctccctc aatcagttgt tttgtatcca aatcataaat
     8641 cgccatacct aattgtttgg gatccacttc agctaatgct ggaatgtaat ccgccacttg
     8701 tcctgtttga taatagtgga aattttttcc aatcaattgt tctaattctt ttacttccat
     8761 ttgaataacc agctttcatt ttttattttt ctgcatgctg gaatttatga cggcatgcgt
     8821 agatcgtaaa tggaataact aagacgataa gataagaaac aatcagaatc gtttcataaa
     8881 tcccatgctg tccagctgcg atactagcag gtggaacaaa tgagatacaa aaagcaaaaa
     8941 gtgaagtcaa aagacctaaa caagcaacga ttacttttac aacttttccg cctggaacct
     9001 gataggctct ttcaagactg tcatctttaa aaaccagctt caaatagccc gcgaaaaaca
     9061 taaagtacaa catcaggtag attacaacag tcaatgacat cgctgcaaga aatgaaagat
     9121 tattcccccc gccgcttaat gtaaagacgg ctgcccagat tgttgcaacg atcccatttg
     9181 cgatcatcaa atgagcagga acaccgtgtg tgttttcttt tgcaaaatat tcaggaagta
     9241 atccttcttc tgctgctacg tgaagtgctt ttgaaggaga ggttacccaa gaagcaattt
     9301 ctccgatgac acctaaacaa acaagaatcg caagaatttt cgcaatccat gcaagatttg
     9361 gatcaatgtg tcttaatagg aattctaacg attgaatcac ccctgtatta agagacaaac
     9421 catgttgagg tactgtagta gcgacggtca atccgccaaa agtatctaaa atgattgcca
     9481 gaataaccaa tacaaacatt gctaatggat aatccttttt agggttttcc atttcatttg
     9541 catgactggc agatgtttct acgcccatat atgctaaaat aaaggaaaca aaaacaacca
     9601 gcgtaggcaa tttcgaaaaa tcaggaatca atgttttcat agacagtatc gtttgtagtg
     9661 gagcgcctga agcgacataa tggatcccta agccaaacaa gactaatgct ggcaacaaga
     9721 taccagctac aaaaccgatc cgagcaatca atgaagtgta tttggttcct tttaactgtg
     9781 agagtaaaat agcccagaaa ataatcaata ggattgccaa tttcagatat ttattgtttt
     9841 gtatagcacc aatacccgtt gcataggata atgcaccagt taagaaatac agcatggtca
     9901 agtagccaac tgttatctca aaccattgga aaaagattgc ggcaaaaccg aatcgttttc
     9961 ccaatgtgcg actgacccaa gtatagacac cgcctttttc ccatcctttc accgttgcca
    10021 tctctgctgc gcacaatgcc acagggataa accatagcaa accgcctaat aacaagaaaa
    10081 atactaagct gaagcctgag gtcgcgaatg tgggatattc atataatgaa acgaccattg
    10141 agatggtcat agccaaaaag ccaaagaacg ttaatttttt tgcaggaatt ttcgttttgc
    10201 tttgttgcat gaatcttcct cttttctatt ttaatttgtt tcaattgagt ttgttgccaa
    10261 agaagaaaaa gtccaatcct tcttcttgtt cttcttttgt agtagtgatc gttgtaaagt
    10321 gcatcgccga ttttaaaatc actgttgtca gcacataggc atacacggca gtaatgatga
    10381 caccaatcac ttgaatccct aagaagtacc agctgcttgg attcgttagt aaatggctgt
    10441 tagatgcaaa gatccctatc agaatcgtac ctgtgaatcc gcccatgcca tgaacacccc
    10501 acacatcaag tgcatcatcc cattgtttct ttttacgaaa atcaacagca gcatgacaga
    10561 cgatacccgc aatgatccca atcagcatgg cactttttgc ttctacataa ccggcacaag
    10621 gcgtaatggc tgccaatcca gcaacggatc ctgttagtac gtcgacaaaa tcaaagccat
    10681 ttccttttac ttttgcaatg atcagccaag taatcatcgc aaatgcaaga gcgatgaatg
    10741 ttgaaccaaa tgcattgact gcttgttcat ctgctcgaag tgcaccaccg gaattaaaac
    10801 cgaaccagcc aaaccaaagc agtcctgtac cgatagcagc tgccataaga ctgctatgct
    10861 gacttctttc tcctaaagga atctttcttt gaccaagtgt gaggatacat gctaaagagc
    10921 cgaatccagc tgtcgtgtgg atgactgctc caccagcgaa atctctaaat cccatctgat
    10981 ccaaaaatcc gccaccccat atccagtggc aaacagggaa ataaatcagc agattccaaa
    11041 aaataacaag tataatatag ccttttaaat tcaatctccc tgcaaaagct cctgtcatca
    11101 aaggaacggt aatcacgata aacatcagtt ggtaaagaaa gaacattaaa aatggaatcg
    11161 ttgcaccatg aaacatgttg gggaagcttg taacatgtct catcaaaaag aaatctgccg
    11221 ggtttccaat aacaccgccg atatcccgtc caaaggccaa tccgaatcca ccaaataccc
    11281 acataatcgt tgttatccca acggagagaa aagattgaga catgatcgtt agtatattat
    11341 tcttccgtgc taatccgccg taaaaaaaag ctagaccagg agtcatcagg caaaccattg
    11401 ctgtacataa aatcatgaat gctgtatctc ctgtattgat aggtaatgta ttcatttttt
    11461 tcgcctcctt tctacgatta cgagtataaa agaaggtgta gttgtttttt tcttctgttt
    11521 ttttgaatta atacttgcat ttataaaaga cagacaatta ataaaagctt gatgtgttgt
    11581 gctctttttc gtttttcaca caaataaaga caaaaaataa acggtcttct ttttatagaa
    11641 aaccgtttat tttcgtcttt ttttattttt aaagatattt tttcataagg aataaagaat
    11701 acttcatata aaatatataa aaaagaaccg cagcgagtgt cgctacggtt ctcaaatttg
    11761 ttcttcattt caacataagt ttttcttcaa tttgcttata atttacgtgc aaagaatgaa
    11821 acgactaata ctaaaatgat tgcaccgatc aatgatggaa tgatagccat tcctgcaatt
    11881 gttggtcccc aagttcctag taaagcttgt ccaattgctg aacctactaa accagcaatg
    11941 atgtttgcga tgatccccat tgatgatcct ttattcgtga ttgctcctgc aattgctcca
    12001 atgataccgc cgacgattaa tgcccaaata aatcccattt taaattcctc ctaactgact
    12061 tcttacttct tattgtacac gtggttcgtt attttctttg actttttgtg cacctttgcc
    12121 tacagcagat tttgctttat ctgtttggcg tgaagcaaat tgtcctgtgg attttgctgc
    12181 ttctgttact ttgtcttgta ctgtttcttg atctttttgg tattcttctt gtgttttgat
    12241 gtctgcaaca ttcacattca cttcgataac atctaaatgt gtcatattgt ttacttcagt
    12301 actgatcaat tctttgattt ggttgtaaat atcttcgatg tctttaccgt attctacgat
    12361 cacatctaga tccacagcta cttgtttctt acctacttct gtattgatac ctgctgttac
    12421 gttatctgtg ttgactaatt tttcagccat atttgagaaa aatccgccat ctaatgtcaa
    12481 tagaccatct acatctttca atgcataacc gatgattttt tggatgactt tgtcttcata
    12541 agtcaattca ccattcatca tgcggttttc tcctttttca tttgccaaaa ctgatccatt
    12601 tgttgtattc atgtttttgt tttccatctt tgtttcctcc tatgatttaa aaaattgatc
    12661 aactattcct gactgtttca aataaaaacc gattcctgcg ccaattgctg tcatgattat
    12721 gatcaacaat gtcttgaaaa atccaatcgt taaccataaa acagctagca gtagtccaag
    12781 acccccaaag ataataggga gcttgtatgc tgaaaatagt tctttcatta tttggccctc
    12841 ctattccact cgagagtgct tgtagtctct tgtatcttct tgttcttcat aaccgctgta
    12901 tgtgactgcc actttgaccg tttcttttgt tccgagtact ttagttactt cttcttcgat
    12961 atcttgcatc aatacacctg ttttccctac taatgaagaa gttcgtttca agtctccgtt
    13021 gacatggata tggattcgat ttttcgttga acgtatccgt actttaggtg aatgaatgaa
    13081 ctcttcttcg tgtaaatggg aacgtaccaa cccttcgatc gcttttttgt cgattgttag
    13141 tttgccatct tcccgtttca taacgaaagt tcctcttgac tttggataga aaagaacgac
    13201 tagcaagatg ataatagcaa gaacggcaaa tactacagct gcccagaaaa tatattgttg
    13261 catgtagtaa ttcgttaaag taaagaagcg aaatcgttcc aattgttcag gcataatata
    13321 cggcgcattg atcaacgcaa tcgctagaaa tactgaaagt agcagtaaac tcatgataac
    13381 accgattatt tttaacccct tattcatttt ccacctccta taaacttatt tttaccctgt
    13441 aaataactct accgacaatc acagtataga tagcgaacag ttagcatagc atcagtaaat
    13501 aaagcgctac caaacattgc tggatcataa cggcgtttta ttgccagtct gatactgaaa
    13561 taacaattgc ttacttattc tctatttact tttgattgct ggctatactt aaaggatatt
    13621 attcaagatt aaaaattgca aagattatgc tcagttatta ttacaagatt ctatttattt
//
LOCUS       DACGLI010000071        13449 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.073, whole genome shotgun sequence.
ACCESSION   DACGLI010000071 DACGLI010000000
VERSION     DACGLI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.073"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(44..1363)
                     /locus_tag="IXT22_002465"
     CDS             complement(44..1363)
                     /locus_tag="IXT22_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4863793.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1360..2013)
                     /locus_tag="IXT22_002466"
     CDS             complement(1360..2013)
                     /locus_tag="IXT22_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4863794.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2301..2821
                     /locus_tag="IXT22_002467"
                     /pseudo
     CDS             2301..2821
                     /locus_tag="IXT22_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2723..3439)
                     /locus_tag="IXT22_002468"
     CDS             complement(2723..3439)
                     /locus_tag="IXT22_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAQ4863795.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(3563..3748)
                     /locus_tag="IXT22_002469"
     CDS             complement(3563..3748)
                     /locus_tag="IXT22_002469"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863796.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            3975..5248
                     /locus_tag="IXT22_002470"
                     /pseudo
     CDS             3975..5248
                     /locus_tag="IXT22_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5355..6386)
                     /locus_tag="IXT22_002471"
     CDS             complement(5355..6386)
                     /locus_tag="IXT22_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4863797.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(6393..7223)
                     /locus_tag="IXT22_002472"
     CDS             complement(6393..7223)
                     /locus_tag="IXT22_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4863798.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(7220..8026)
                     /locus_tag="IXT22_002473"
     CDS             complement(7220..8026)
                     /locus_tag="IXT22_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4863799.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(8032..8856)
                     /locus_tag="IXT22_002474"
     CDS             complement(8032..8856)
                     /locus_tag="IXT22_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAQ4863800.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(8846..9946)
                     /locus_tag="IXT22_002475"
     CDS             complement(8846..9946)
                     /locus_tag="IXT22_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4863801.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            10124..10909
                     /locus_tag="IXT22_002476"
     CDS             10124..10909
                     /locus_tag="IXT22_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAQ4863802.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            10942..11325
                     /locus_tag="IXT22_002477"
     CDS             10942..11325
                     /locus_tag="IXT22_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4863803.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            11401..11532
                     /locus_tag="IXT22_002478"
     CDS             11401..11532
                     /locus_tag="IXT22_002478"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4863804.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            11501..11737
                     /locus_tag="IXT22_002479"
     CDS             11501..11737
                     /locus_tag="IXT22_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4863805.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(11815..12786)
                     /locus_tag="IXT22_002480"
     CDS             complement(11815..12786)
                     /locus_tag="IXT22_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAQ4863806.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         4089 a         2926 c         2326 g         4108 t
ORIGIN      
        1 taagtctcta tttttcaata actattgcaa aattatatct taattaagaa aatattttta
       61 ttttaaagat aaaaaattct tcatcctgca atactttata ttctatattg taattattca
      121 gaatattact tacaatatat aaacctaatc cattactatt ttccttattt aaatcaaatt
      181 taacatcaaa tattttatcc atattcgaaa ttttattgtt accgtatgaa ttctctatat
      241 ataaccaatc attaactatc ccaatattaa ttaccccatt tacatcagta tattttaccg
      301 cattactaat caaattagat agaataatct ttaaagctgt ttttcctata taaacattct
      361 cgtctaatat ataattattg acagttattt tcttttgatt tgctaatatt tcatactttt
      421 ttaatatgtc ttctaatgta tcatttattt tcaaatattc ttcatcatta ttcaaatttt
      481 ctatagaatg aactgataat atttgagaaa tattttttgt taaactatca acgatttcaa
      541 tacattcatt aatataaata tctctttctt tatattttcc aatattgtat ttcatgtttt
      601 ccagtattat tttaagacta gcaagagggg ttttaagttc atgggatgca cctttaaaaa
      661 agtcatattt taacttttct aattttaaaa tttctttatt tttaaattcc aaatcgtcaa
      721 ttgttcttaa taaagtagaa tacaaatcat taatttgttg ttttaattct ccaacttcat
      781 cattagagct aacttttaaa ctcatttttt tatcaagttt catcatttta tcagtaacaa
      841 tttttatttc ttgtatatta ttttttattg attttgcata aattaaagaa ataatagcag
      901 aaaataaaat tgatattaat aaagaatatg gtaaaaattt aaggcttaaa tctttcgcat
      961 ctttttgcat atcagctgta gaaacaaatt gtagatttgt ttttttacca tcattaagct
     1021 ttatttctct ttcttcaatt atcaaagaat tactatcact ttctaaatta acatttatat
     1081 tatctttgat ttgtatttca ttcttattat ttttttcttt tatgaatact tttatttcac
     1141 tactcttgga ataaaactcc aaagtttgtt ctatatattt tatttctttt ccattcatat
     1201 tactagaaat ttcatttgcc atattatgaa tcttttcttt tctcgtctcc aaatatgttt
     1261 taggaaagat aaaaaaaatt aatgaatgaa ctaatataat tattattcca agaacagaaa
     1321 atatttgtat gaacattttt ggaaatatct ttaatttttt cattttctct ccaatttata
     1381 tcctacattt cttatagtag ttatacagtc taattgtaat ttttttctaa gttcttttat
     1441 atatacatct attactcgat cataaggagt ttcttcgcta tctttccata cataatcaat
     1501 aatttgcatt cttgttaaca cttgtccatt attatccaat aaacatttta atacttctag
     1561 ttcttttgca tttacatcta tttcttcacc atttatttta gctgtatagc tattaaaatt
     1621 aaccgataga tccttatatt caaacttctc taaatgtcca taattcttct taattaaaga
     1681 atctattcta gcttttaaga ccggcaatga aaatggcttt tctacatatc cgtctactaa
     1741 attagtaaat gcatcaattt tatattcttc atcactaaat gcagtcaaga ttagaattgg
     1801 taaattgctt ttctttctaa tttctttcaa cacttctaaa ccatttataa aaggtatctg
     1861 aatgtctaag ataaccaaat ttatatcgct attaaatttt gacaaggctt ctcttccatc
     1921 tttagcttga ataacagtat atccaaattc tgaaagatat tcacttattc cctctcttat
     1981 catattatca tcttcaacag ttaatatttt catatatacc tccacttaag cctatacact
     2041 agatattata cagcatatta tggctctata atatctagtg ttggtgacgc cttctgttgc
     2101 caatactttt tctttttttt aataaatgca aacagacacc ttgaaatcct ttagaaaaaa
     2161 ggcttctata atattttgtg ttgttggaaa atcgaaggcg attttctact aacacttttt
     2221 cttcgtttca actcaaaaag agactcactt ttggtaaaat ttagtcgacc aaaacatcac
     2281 cctaccaaag gagtcgctct atggataatc atactagaaa attactcgga ttaacagata
     2341 aacatttatt ttttgatgaa gaatggctga ttgaaaaaga atataaaggc gttcaagcgc
     2401 agtttattaa agggagattg gatgactcac cttcccattg tgaacactgt ggatcgattc
     2461 gtattatccg caacggttcc tatacgacac gtactcagat gttgaaagtc aaagaaaagt
     2521 tgactatttt agaattaaaa cgtacccgtt ttctatgcta tgattgtggg cagacctttt
     2581 ctgcgaaaac ggacttagtt gatgaacatc atcaactaac aaaggaactg aagcaggcga
     2641 ttctcataga actgtacgaa aatcaatcac gtaatctgaa aatcagaaga agtaccgtcg
     2701 gctcaagcga tattggaaac tcttactcaa agattccacg acattggagc cgctcaaacg
     2761 gcattatcat cgactgttta aacgaccaat tagtcaaaca gaaatcgtcg atgaaccgtt
     2821 gtgcacaatg gtgtcctgaa cgtacagcga caccttccat atccagagca gtcgccacat
     2881 cacggggatg gatgccatcc aaattaaaag caaccacgcc agtatgatgt tcaggatctt
     2941 gcggtccgta aatggtgata ccgccgatcg cttgtaattt aggtaaaacg taggcaacca
     3001 gttcttgctc ataacgatga atattctcca taccaatctc attcaagtaa tcgattgctc
     3061 ctgcaatgtt cggagtacca gcttcaaatt tccatggcag ctctttccat gaactatcgt
     3121 aaagattgac aaaatctatc atttcaccgc cgaattcgac tggctccatt tgttctaaca
     3181 attgacgttt gccatataat acaccgattc ctgtcggccc gcacatttta tgcccgctaa
     3241 aggcgaaaaa atctgcatcc aacgcttgta catcaactgt catatgcggt gctgcttggg
     3301 caccgactgg actatcctca actacaacag cctgttcaac cctcagccgt ttcaagcaca
     3361 acaaataacc ttctggatct ggtttgccga cctgaagatc atcgatcgtc acaaaggaat
     3421 caattttttc cttaatcatc ggatgtgctt caaaaaaata gtctagctcc cgcagttcag
     3481 aattgagact actccgattt tccagtgctg ctgatccgct gctcaaaatg ttcagcatcc
     3541 actggtctcc caaccgcttg acttatccct tcataaaagg acagttctgc tgccgtccca
     3601 acaccttgtt gatagtctgc aaaaggaatt ttatagccga actgctccag taaataggct
     3661 tcagtaaata gtgatgaata ctctcgtaaa acatccattc actgtcaatc atcgtcccat
     3721 caaaatcaaa aataagtgct ttggtcatct tctttccccc ttacccaaaa caagcaaaag
     3781 ctgtgtcctg ctctctctac agtatcagca taaaaactgc cgtctgaaaa gtcaaaggtg
     3841 aaagaaatgt ggcgctataa tttctaggac tgatagtaaa tcattctatc agtccttttg
     3901 agcataaaaa aacaaaacat acagaagctc cgttagaatt gaatcaccac aacacaatca
     3961 aaggagcgtt ctgtatgcct gatcttcatc ttatcaaact attactagga atcaaagatg
     4021 gaaacattca aatcactcat gtcgagaaga aaaaaataca ttcaatcaac agtatcgttg
     4081 tttctgccac gctcattaaa acgattcagc cctgtcctca gtgtaaacag gtgaatcaac
     4141 atgggctgat cgttaagaac ggaaagaaaa aatcgctggt ccttctcaat aagtgtgcga
     4201 atcaacggac ttatcttgct ttggcaaagc aacggtacct ctgtcgtggc tgtcacacct
     4261 attttacggc gaatacctac attgttgaaa aaaactgttt tatcgccaaa caagtacatt
     4321 ataaaatatt ggaggaattg actgaaaaac aagcaatgac gacgatttct aaacattgcg
     4381 gcgtttcttg gtcaaccgtt tcgcgaacac tcgcttctct gctccccatg acaaacgtga
     4441 aaataaattg gttgcctcgc tgttcattgg tagatgaatt tcgttcattg aaaaatcaag
     4501 tcggtcccta ttctttttct tgtatggatg gcgatactgg gaaattactg gatattcttc
     4561 cttcacgtaa gaagaaagat ctcatttctt attttatgca atttgaacga cgtgcacgtt
     4621 taaacgtaaa aatactcgta acagatatga acgcctctta tgctttgctg ataaaagagt
     4681 gctttcctca tgccaaactc gttgtggatc gctttcacat cgtcaagcac ctcattcgca
     4741 gttttaagga tatttgacta tgagtcatga aaagcttcga ccgaaacgat ccaatacaag
     4801 ccaaacacta tcgacaagtg aaggctttat ctcgacttct gatcaaacga caggacacgc
     4861 ttgtttatga taaatggaca aaatggcgta attttggttg ggcctattta accgaaagtg
     4921 aagtcgtaga acgtctactt tctacttctg atgaactacg aatagcttat gcttactatc
     4981 aagaaattct tcaagctttt tatgacaaag aagcggacat cttctttcag cttgtaaaaa
     5041 caatgcccaa gtcggttcca agagaactgc atcatataaa aaaagcgttt ataaactatg
     5101 aatccggcat tcgtttagcc ttagagttgc cttactcaaa tggcaaaata gaaaatctgc
     5161 atacccacat caaagcattg aaacgaatag cttacgggtt aggatgagaa ccagaatttt
     5221 cttaatcaat catctgatca cttattaaac ataaaaaaac atctaaagca gaaaatcaat
     5281 tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag ccagaaatgt
     5341 ttgccgacta tacactagct ttgttgtgca aaatgctgag tatcaatttc cacagggatt
     5401 gctagaatat ctttcagctg aatgtataag gcatcgctaa ttttctcttc ccgatcgttc
     5461 aaccgatcca ctaaaatttc tttgccctcc agcgtttgaa aaacataccg ttgaatgttg
     5521 cctaaaataa atgattcctt ccatagaacc ggaatcttaa ccccctgagg aaccggttca
     5581 aattgaatca gctccggtct taaataataa atgcagcgat tgcccttagc ggaaaactcg
     5641 tgggtatact gattcagctc ataccattcg aaacgattat agttgccgat aaattccgca
     5701 acaaatcggc tctgaggatt ctgatacaat tccttcgagg tggaaacctg agccacccgc
     5761 ccagcttcca tcacaaaaat ccgatcactg attcgcatcg cctcttcttg gtcatgagtc
     5821 acaaaaatca tcgtcatccc tagcgattgc tggatagcgc gcaaatcccg ctgcagctgt
     5881 tttctaattc gggcatccaa agcacttaat ggctcatcca gcagcaggac tttcggttca
     5941 gtgaccaatg agcgagccag tgccacccgt tgtcgttgac cgccagaaag aaactggaca
     6001 tttttatctg cctgctccgt catatccacc aatgatagca tctcaaaaac cttttcctga
     6061 atcacctcag gactcagctt ctttaccttc aaaccaaagg ctacattttc aaaaacagtc
     6121 atagttggaa acaatgcata ctgttgaaaa acaaagccga tattgcgatc cttcgtaggc
     6181 ttatcggcaa tattctcatt gtccagcaca atctcaccgc tctttggttg ttccaatccc
     6241 gtgatacagc gcagcaacgt agactttccg cacccgctgg gacctagtaa agtaaccagc
     6301 tcaccctttt caatctgaat ttcatcaata gctaaaatct gtttttcatc aaaaaacaga
     6361 ttgagatcat gtatttctaa aaacattttc cgtcacaact cctttaaggg cttctttttc
     6421 gactgcttct cttccctcgt ctgcttaagg gacagctgtt gcttttgtcg ataagtcagc
     6481 ataaaggtag ttaaagcaat tcccaccata aacagcaaat acaaaaccat cacagcgcta
     6541 gccaaatggc cgttttcgtt catccgccgc agcatataga tgcgtaccgt ctgaaatcga
     6601 ccgccaatca acaggttcgt cagcatgtac tccccaaaaa ccgaagaaaa aatcatcaga
     6661 gaaactaggg tcacaccgat acggatgttt ggaaacagca cctggataat aatcgtagac
     6721 atcggggcgc ccaaggtttc tgctgcatcc actaattcct tcagattaat taagcgcatc
     6781 tggttgttaa gactaagata gacaatcggc aacgccgtaa taaacaatgc acctaccaac
     6841 actacaaaca ttgggatacc agtttcagca tacgttcgaa gcaaagccgt taccaaaatc
     6901 actcctggta aagcatacgg cagcaggagc agcttttcca gccaacgatt caaacgaggg
     6961 aaatacaaat gaatccaaat aatggtggga atcatcaaca acagaatcgt caccaagacc
     7021 acacctgcta ataaaagtga gcgacccacc gcagcaataa attccctgtc cgtcagcagc
     7081 tgttggaacc attgcaaggt aaaatcacta ggtaaaagcg attttgacca tttagtggag
     7141 ctggcataca aaatcgttcc aataatcggc agcaagtaat acaggacaaa gcagaacaaa
     7201 atcggtttta ttaacttttt cacgtctgca ccaccttgcc tttcttttga ataatcaaca
     7261 ttgccgttac cagcaggaca cctaaagcga ctgccaacgc actgcctaaa ttaggcttgg
     7321 cgaacacatc tcccgacact aaagccgcaa ttcgaatcgt taaaagattt acattactgc
     7381 tggtcagggc atacgctgtt tcataggtcc ccatgccatt agcaaataag atgacaaagg
     7441 tgctggcaat cgatggtcgc aaaaaaggca aagccacctt gaaccaagca tacgctgatg
     7501 aagcgcccag caattgtgcg gactccagcc attccttttt cacttccttc atgctgggat
     7561 acaaaaacaa gacccctaac ggaatttgga aataggtata cgtgatggtc aatccccacc
     7621 aagaatacaa attgaagtcc gctagaaatg gcaaaatcat tttcagcaca cctacattcc
     7681 ccaacaaaat aataaaagag aatgccagcg gaatcccagc aaaattagct gccaaattgg
     7741 aaacaaaggt gattttctcc tgcaatttag tcgatagatt cattaagcat aaacataaaa
     7801 taaacgtccc gattaaccca atcacactgg agctgacagc aatcagtacg ctgttaacaa
     7861 aggcctgtgt gtaatatttg ttgctgaaaa tatcactgta attggccaat gtccactggt
     7921 tagttaaatc actgtgcaag ctgcacagaa ccataaaaag cagcggcagc agtaaaaatg
     7981 cacagaagat aaaggaggca ggaaccagaa ccaagcgttt tttcatctct ttcatcccct
     8041 catcaattct tgaatgtcct gcattttctc tgacggtgca attcctaata accagcaaaa
     8101 caatggagcc gccagcagct gtggtacagt ttgttccttc agcttttggc gtttatttga
     8161 aatcaaataa aaaggaactt cacgatgtgc agccaagctg ccgccatgca gtccgtgcgc
     8221 atccatcccg tgatccgcag tcaccacgac ttgataacct ttttgcagcc attcaggaag
     8281 gtaaatagcc aataatctgt ccgcctgatt aaccgctgct gcatattcat gagaatcggc
     8341 ggtaaatttg tgaccgacat catcaatatt catcgaatgt acgaccaaaa agtctggctg
     8401 atactgattc actaaataat gggcatccgc aaataaatgc gaatcagggt aagtgtcctc
     8461 actataaaag atgccatgct gaatcagtcg ctcctcctga tgctggatgc gatcaaccaa
     8521 acgattatag ggggcttgat tgtacaactc gctgtaccag tggtaagcgg cggctcctgt
     8581 ttttccgcca gcttccttaa ctaattcaaa cagcgaccac tctttggatc gctgagcatg
     8641 gtaattacta tagatgccat tttcataggc tggaacgccg gtcatcagta cttcgtataa
     8701 cggacgtgaa ttgctgggca gctcactttt taccttcaat aagcttgctt gctggtgctc
     8761 aactaaatga ttcatgaacc caagctgggc gacggctgtg tcgtagcgac agccgtctag
     8821 tataactaca atcagtttgt caagtctact ttgcataggt cagtacctcc gcctgccaaa
     8881 gctctggaag ctctacagag gtcttgttcc aagcttcatt gtcttcaact ggcaccgccg
     8941 cttcataagc atcctccggc agtaattttt cagctacttc tttaggcagc tctaccttgc
     9001 gaataggtcg cgcatagccc tttgccaaat tgatttgccc ttcatcagat aaaatatatt
     9061 cccgtgctag ctttgccgca ttgggatgag gggcattttt attgattaag gttgtatacc
     9121 cgctaatgat ggagccgtct gttggcacag ttacctcaaa acgctcggag tcaatttggt
     9181 cacgataatt tagtccattg aagtcccaaa caactgccac atcgatttca cctttttcaa
     9241 gatttgctac gctggcatca acggtggaca aacggccttt ttctgccatt tttttgtagt
     9301 aattcagacc tggctgaata tccttttcgt cacctccgtt ggcaatcgcc gcagccaata
     9361 cagcaaattg tgcttggttg gcaatcgtca catcccccac gctaacttga tagtcaccct
     9421 cttgcagctc cttccagcta gtcggtgctt gcttcacatt ctctttatcg gtgataaagg
     9481 aaatggttcc cgtatagctt aacaaccaat ccccatcatc atcctttgcc caatccggaa
     9541 tttcctccca atagttggtc ttataaggta aggttaactc tttgctttca gccaacggac
     9601 cgaagctgat accgacatca ccaatatcgg cggttccatt ttttccttct gattcaaact
     9661 tagccaattc ttctgcactg gacatatccg tatccacgtg acttaagccg tattcttttt
     9721 caaggtcgtt ccaagtgcct acccaatttg cccaagtatc cggcattccc aagctggcaa
     9781 tctctccttc ttccttggct ttttctataa tcgtatctaa agagtcgtct gccgcagccg
     9841 attgcttcgt tgcttcacct gagccgcagc ctgtcagcag gatacttact gttgctgcac
     9901 aaaataaacc gatagtcatg ttacgaattt tttcattcat tttcattcat tcttctcccc
     9961 tttcgataat tccattctaa caaagctttg taatgagaga atcagtttct tgaaaaggtt
    10021 tcatgaacaa tgtaaaggtt gtatatggtt tgtaaatttc gacgaattcc cgttaacctt
    10081 ctaaagcttt tgcggtatga tagtagaaaa aaggaggctc cctatgcagt attatgatca
    10141 gcatctccac acgtattttt cctttgattc agaggaaaaa tttgaaaact atttagccta
    10201 tcagccggag tttttcgttt ctacggatca ctttgattta aacaatccat ctaccggaaa
    10261 agatgacatt ccggattatc cagcctatat aaacaaactg gactctttaa aagaaaccta
    10321 ttccaccaaa tttctgcgag gtatcgagat tggcgttgtt ccaggacaag aagagcggat
    10381 cgtggattac ctcgctcagc atccttatga tttaaagctg gtaagtattc atcaaaatgg
    10441 ccgctttgat tatatggacg atgtggtttt aaccaaagat cccattcaaa ctaccaagga
    10501 atattttgat cagatgttgc aggtcttgac ggattttcca gaaggagata ttttgactca
    10561 ctttgattat ggattacgcc gcttcacctt cacagcggaa gaattcgcgg agcattttga
    10621 ggctcagctg ctaacgattt tcaaaaaggt tgttgaacga gaattggcga tggagttaaa
    10681 tgccaagagc ttcttgaaat acggcaacga agacctttac cgttatgccg ttcctttgta
    10741 tcaaagtgtc ggcggaaagc tctttacctt aggctcggat gctcatgttg ccgaagatta
    10801 tcagctgggc tttaaaaaaa tgagtcagct gttggcagac tgtcaggtag aaaagttgct
    10861 agtcattcaa ggaaaagaac gccgcctgac gccgctgccg attttgtgat tcctatataa
    10921 tagaagaaag tggtgaaaaa aatgagcaac ctgtgggact acaatcaaga ggcacccatc
    10981 cattatttaa ttgcgcgaca ttgggatgcg ttgaaaattg aggcggtttg ccgatccttg
    11041 ttagcagccg ttccaaaaca acaactggaa aattttttgg tggctgacag cttgcagcgg
    11101 gaaaaagttc aggcttattt tgcagccttt aaagatcagc ctttggaata tttgcatgcg
    11161 cagtttcatc ttttttatca agtagccgcc ccagatgact acaacgattt acgaggacag
    11221 ctgcaattga cctttcaagc ggatgaaacc gcctataccg ttttattggg aatggctcgc
    11281 cttggtgatc aggcgaaggt cgagtggcgg attttcgata tttgatggca ggatcaaggc
    11341 gtttcagttg caaaccttcc tctctttcaa ttagaaaaac cgcagcagga agaagtttgt
    11401 gtgctggtca ccgatgctgg tgaaattcgt ctccgcttat ttcctgacca agctcccctg
    11461 gctgtagcca actggcgctc cctagctgag caaggcgttt atgacaacac acctttcggc
    11521 tcgtgtcatt aaggaatttg ttattcaagg tggcgctttg gatggttctg gtgatgaagc
    11581 tgtttccagc tatgagggct ttttcgctga tgaagtgcat cgcggacttt atcattttaa
    11641 tggcgccttg gccttagggg accacggccc ccacaccaac ggcaaccagt tttttattgt
    11701 gcaaaacaca aaggcgcagg ctgacctgct aatgtaaagc aagcatactt ggagcttgga
    11761 ggactaccgg agctggatgg tcgttatact gtttttggac aggtatacca agggttagaa
    11821 atcgtagcag cgatcgcagc tcagccgaca aacagtgaag atgtaccgat tgagccagtg
    11881 ttcattcgac aaattaactt cgaaaaaaca tcgtaaaaag acactcactg acttcagcaa
    11941 aagctctatt cttgagctgg ctgcagctag tgagtgtctt tcatttatcc ataagataaa
    12001 gcttggattc aataaataaa taaatgtttt ggttaaagct gtgaccagca aatgaggaac
    12061 cgtgcgagcc agttgatctg ccaatgcaaa catttcttta ggtgaaggcg ctggcgtgtc
    12121 tgccaacgga tactccagtc ccaatgcttg gtaaccgtgc ataccatagc agtggtacgg
    12181 tagtaattct aacggtacga accgatcaag atctgccaca aaacaagcaa tcgtcagcag
    12241 ctcggtcagg ttcatattga tacctggaac cacaggaact cgaattcgca cttcgcagtt
    12301 aggatactca attaaaaagc gacgaatatt cttcaaaatt tgttggttat ctaagccggt
    12361 ccattgtttg tggagcttgc tggtaaacat ttttacatcc acaaacaatg tatccacata
    12421 gggagctacc ttttggattt cattataagc accacaaaag ctggtttcca gtacggtatt
    12481 gattccaatg tatttcgatt tttgcaaaat ttctttagca aaatccgcct gaaccagtgc
    12541 ctcgcctccg ctaatggtca ctccgccatc cgagtgaaag taaaaaacag catccttctc
    12601 aatctcatcc attacctctt cagcggtcat ggtctggcca aatccttttt caatctgctt
    12661 gctttgtgat tcgggaatcg aacaccaggc acagcgtaat gggcagccct ttaaataaac
    12721 aacggtccgt aaaccagcac catcatgtag agaaccctgt tctattctta atactgttcc
    12781 ttccatatag atttttgaat tacacactag tttaaactaa aacacacaag gaaaaactta
    12841 ccatttaatc ataaaattag ctcatataaa tatactagga tgtaaaatag actggtcaaa
    12901 atctggtcaa aaaagaggac taatacaggt agtcctcttt tttgttattt taatattcta
    12961 aatcattttt tattggttta ttcccttatt cgatgtagac tcaaatcact atatcactag
    13021 atatcaaacg gcgtcatacg gaatcaaaaa catcaaattt gacctgttaa atggtcattg
    13081 aataacattc aaaatcaata aaacggagtc agacacggag tcaaaaacgc tgagagtaaa
    13141 aaatatatac agccttgtag gtaaagtacc acagggctgt atatttttta tttcagatta
    13201 ccttaaatga ttccatttac tttttatctc attttttcct actagttagt atcaaatact
    13261 ctcctatttt ctcaataaac tatttttgga tacatggtat ctgaaacagc taaaaccttg
    13321 tcattacagc aaaaaatcac gttatccaga ctgtagacaa agtccatttt atggatgatg
    13381 tctacagtct tttcttttat aatagattta tgaaaacgaa tgcaaggagt gatagctatg
    13441 atgtctaaa
//
LOCUS       DACGLI010000072        13432 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.074, whole genome shotgun sequence.
ACCESSION   DACGLI010000072 DACGLI010000000
VERSION     DACGLI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.074"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..197
                     /locus_tag="IXT22_002481"
     CDS             <1..197
                     /locus_tag="IXT22_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863807.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="IXT22_002482"
     CDS             314..811
                     /locus_tag="IXT22_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4863808.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="IXT22_002483"
     CDS             898..1290
                     /locus_tag="IXT22_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4863809.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..3721
                     /locus_tag="IXT22_002484"
     CDS             1274..3721
                     /locus_tag="IXT22_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4863810.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3724..5907
                     /locus_tag="IXT22_002485"
     CDS             3724..5907
                     /locus_tag="IXT22_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4863811.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5904..6905
                     /locus_tag="IXT22_002486"
     CDS             5904..6905
                     /locus_tag="IXT22_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4863812.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6920..7834
                     /locus_tag="IXT22_002487"
     CDS             6920..7834
                     /locus_tag="IXT22_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4863813.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8079..8195
                     /locus_tag="IXT22_002488"
     CDS             8079..8195
                     /locus_tag="IXT22_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4863814.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            8211..10130
                     /gene="tet(M)"
                     /locus_tag="IXT22_002489"
     CDS             8211..10130
                     /gene="tet(M)"
                     /locus_tag="IXT22_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAQ4863815.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10228..11601
                     /gene="tet(L)"
                     /locus_tag="IXT22_002490"
     CDS             10228..11601
                     /gene="tet(L)"
                     /locus_tag="IXT22_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAQ4863816.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            12165..13427
                     /locus_tag="IXT22_002491"
     CDS             12165..13427
                     /locus_tag="IXT22_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid recombination enzyme type 2"
                     /protein_id="HAQ4863817.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
BASE COUNT         4328 a         2335 c         2829 g         3940 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
     2821 tgaaatcaat atcgtcaatc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
     2881 tgtaattatg aaaaatacca aagattctga atcactggct attgatattt tgacattcct
     2941 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
     3001 agtaaccaat agtgaagtgc gagggttgat gaaagtgatt gaagaattac gggttgagaa
     3061 tacgccacta agtaccagca tagccgacca tatcgaaagt tttacagact atgactttgc
     3121 ccatctgctt tttagtgatg gttatgtaga gcagtctatc agccttgaaa aacaactgaa
     3181 cattatacag gttgccgact tggtacttcc tgacaaggaa acttcctttg aggaatatac
     3241 cacaatggag ttactatcgg tagcaatgct gattgtcatt agtacctttg cgttggactt
     3301 tatccataca gaccgaagta ttttcaagat tgtagactta gacgaagcat ggagcttctt
     3361 acaggtggca caagggaaaa cactatctat gaagctggtt cgtgctggtc gtgctatgaa
     3421 cgctggggta tatttcgtga cccaaaatac agatgacctc ttagatgaaa aactgaaaaa
     3481 taacctcggc ttaaaatttg cctttcgttc cactgacctt aacgagatta aaaaaaccct
     3541 tgcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
     3601 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
     3661 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
     3721 aatgtgaaac catcaatatt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
     3781 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
     3841 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
     3901 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
     3961 ctaccgtgga actggtcgga cggaattgga aaacaagtca tgtatggact atatgccatt
     4021 accaatttta tttggacaat cagtctttat gtttccaatg cgacgggtta cttagtacag
     4081 gaagcctatt ccttagactt catttccgct acagcagatt ccattggcaa gaatatgcag
     4141 acccttgcag gggttacgcc tagtggacta tcaacagagg gtttctatgt tggattcctt
     4201 ttactcttga ttttggttct tggggtttat gttgcctata caggactgat aaagagagaa
     4261 accacaaagg caattcatgc cctcatgaat tttgtgctgg tttttatcct atcggcttcc
     4321 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagc
     4381 aacgctagtt tgtcactggg tacaaaaatt gtcatgcccc attcagatag tcaaggcaag
     4441 gacagtgtgg acttgatacg tgacagccta ttttccatac aggttcagca accgtggcta
     4501 ctgcttcaat ataacagttc agacattgaa agtattggta ttgaccgtgt ggaaagcctg
     4561 ctctcaacca gtccagattc caacaatggg gaagacagag aaaaaattgt tgcggaagaa
     4621 attgaagata gaagcaatac caatatgacg attacaaaga cgattaaccg tttaggtaca
     4681 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
     4741 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
     4801 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
     4861 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
     4921 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
     4981 gtgacctttg caggaatcta ctttaagctg ggcgatttaa tgagtatgtt ttctctacag
     5041 agtaacgatt ctcaaagtgt gggaagtcgt atgatgagaa aacctcgtat gcttatgcac
     5101 gctcacatgc accgtctaca gcggaaactt ggacgctccg tgactgcttt aggggctggg
     5161 tctgccattg ccagtgctac gggtaaaaaa ggacagtcgg gttcgggaag ttctgcgagt
     5221 acacaagcag atcactctcg accaaacggg caggaaaaat caacactagg aaagcgtatc
     5281 ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagatac tgctggtaat
     5341 ttgaaagaac aggttaagga tttgccgacc aatgcaagat atgcagtata tcaaggaaaa
     5401 tctaaagtga cggataatgt ccatgattta accagaagta tttctcaaac caaagcggat
     5461 aaagccagtg gacgcaagaa acagcaggaa caaagacgga aaaccattgc ggagcgtcgc
     5521 tctgaaatgg aacaggtcaa acagaaaaaa cagccagctt cttccgttca tgaaagacca
     5581 gccactaagc aagaacaatc tcatgatgga cagacttcaa ggcaaacaac tgtacaggct
     5641 tcctataggg aatctcaaca agccaaacaa gagcgtccaa cagttaagtc cgattcttca
     5701 agtttaaaaa cggaacgtca aagtaataca gttcaagaaa gaacggttca aaagccagta
     5761 acttcaactg caccaacaga tagagcttca caacgttcaa tcacaaaaga acgtcagtct
     5821 actgttcaaa gagtaccact acaaaataca aaaagtagac caccaatcaa aaccgccacc
     5881 attaagaaag gcagtaagaa accatgaagc tgaaaacttt agtgattggt ggttcgggat
     5941 tattcttgat ggtcttctca ctgcttctgt ttgtcgccat tttattttca gatgaacaag
     6001 atggcggttt ttccaacatt cactatggcg gtgtggatgt ttccgcagaa gtgctggctc
     6061 ataagcctat ggtagaaaaa gttgccaaag aatatggaat tgaagaatac gtcaatatac
     6121 ttcttgcgat tatacaggtg gaatcgggtg gtacagcaga agatgttatg cagtcctcgg
     6181 aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag caaggtgtga
     6241 agtatttcag tgagttatta gccagtagcg aaaggcttgg tgtagattta gaatcggtta
     6301 tccagtccta caattatggt ggtggtttct taggatatgt ggctaatcgt gggaataaat
     6361 atacctttga actggctcaa agtttctcaa aagagtattc gggtgacgaa aaagtgtctt
     6421 accccaatcc catagccata cctatcaatg ggggctggcg atacaattac gggaatatgt
     6481 tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat gatacagtac
     6541 aagccatcat ggacgaagct ctgaaatttg aaggctggaa gtatgtctat ggcggagctt
     6601 ccccgactac ctcttttgat tgtagcggac tgacacaatg gacgtatgga aaagctggaa
     6661 tcaacttacc acgaacagca caacagcaat atgatgtaac ccggcatatc ccattattgg
     6721 aagcaaaagc cggcgatttg gttttctttc attctaccta taacgctggc tcttatatta
     6781 ctcatatcgg gatttattta ggcgataacc gtatgtttca tgcaggcgac cctatcggtt
     6841 atgccgactt aacaagctct tactggcaac agcatttagt gggagcagga cgaatcaaac
     6901 aataagaaag gacgattcaa tgatgaaatt cggaaaaaat cagaatacag aaaaacagac
     6961 accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cgtaaaaagg ttgtgattgt
     7021 cctatgggta cttttaggac ttagtttcag ctttgcgata ttcaagcact ttacagccat
     7081 tgatacccat accattcatg aaaccaccat catagaaaag gaatatgtcg atactcatca
     7141 tgtggaaaat tttgtagaga actttgcgaa agtctactat tcatgggaac taaacgacaa
     7201 gtccattgat aatcgcatag aaaacctgaa agcatatctg acagaggaac ttcaagctct
     7261 gaatgtcgat acagttcgta aagatattcc tgtatcgtct tctgtaaaag gatttcagat
     7321 atggacggta gaagcagatg gcgacaatca atttgatgta acctacagtg tagaccaact
     7381 cattacagag ggggaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
     7441 agacagtact ggaaatatgg tcctcattaa gaatccgacc attactagca taccaaagaa
     7501 atcagactat aaaccaaaag ctattgaaag tgagggtacg gttgattcca ttacaaccaa
     7561 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
     7621 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
     7681 agaactggta aatcctattt acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
     7741 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
     7801 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
     7861 ttttgtaatc acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt
     7921 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
     7981 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
     8041 ttagtttttt gcacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
     8101 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt
     8161 atcactggga tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta
     8221 ttaatattgg agttttagct catgttgatg cgggaaaaac taccttaaca gaaagcttat
     8281 tatataacag tggagcgatt acagaattag gaagcgtgga caaaggtaca acgaggacgg
     8341 ataatacgct tttagaacgt cagagaggaa ttacaattca gacaggaata acctcttttc
     8401 agtgggaaaa tacgaaggtg aacatcatag acacgccagg acatatggat ttcttagcag
     8461 aagtatatcg ttcattatca gttttagatg gggcaattct actgatttct gcaaaagatg
     8521 gcgtacaagc acaaactcgt atattatttc atgcacttag gaaaatgggg attcccacaa
     8581 tcttttttat caataagatt gaccaaaatg gaattgattt atcaacggtt tatcaggata
     8641 ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa ggtagaactg tatcctaata
     8701 tgtgtgtgac gaactttacc gaatctgaac aatgggatac ggtaatagag ggaaacgatg
     8761 accttttaga gaaatatatg tccggtaaat cattagaagc attggaactc gaacaagagg
     8821 aaagcataag atttcagaat tgctccttgt accctgttta tcatggaagc gcaaaaagca
     8881 acatagggat tgagcagctt atagaagtga taacgaataa attttattca tcaacataca
     8941 gaaagaagtc tgaactttgc ggaaatgtct tcaaaattga atattcggaa gaaagacaac
     9001 gtcttgcata tgtacgcctt tatggcggaa tcctgcattt gcgggattcg gttagaatat
     9061 cggaaaagga aaaaataaaa attacagaaa tgtatacttc aataaatggt gaattatgta
     9121 aaattgataa ggcttattcc ggggaaattg ttattttgca aaatgagttt ttgaagctaa
     9181 atagtgttct tggagataca aagctattgc cacagagaga gagaattgaa aatccgctcc
     9241 ctctgctgca aacaactgtt gaaccgagca aacctcaaca aagggaaatg ttacttgatg
     9301 cacttttaga aatctccgac agtgacccgc ttctacaata ttatgtggat tctacgacac
     9361 atgaaattat actttctttc ttagggaaag tacaaatgga agtgattagt gcactgttgc
     9421 aagaaaagta tcatgtggag atagaactaa aagagcctac agtcatttat atggagagac
     9481 cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc gccaaatcct ttctgggctt
     9541 ccattggttt atctgtatca ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg
     9601 tttctcttgg atacttaaat caatcatttc aaaatgcagt tatggaaggg atacgctatg
     9661 gttgcgaaca aggattatat ggttggaatg tgacggattg taaaatctgt tttaagtatg
     9721 gcttatacta tagccctgtt agtaccccag cagattttcg gatgcttgct cctattgtat
     9781 tggaacaagt cttaaaaaaa gctggaacag aattgttaga gccatatctt agttttaaaa
     9841 tttatgcgcc acaggaatat ctttcacgag catacaacga tgctcctaaa tattgtgcga
     9901 acatcgtaga cactcaattg aaaaataatg aggtcattct tagtggagaa atccctgctc
     9961 ggtgtattca agaatatcgt agtgatttaa ctttctttac aaatggacgt agtgtttgtt
    10021 taacagagtt aaaagggtac catgttacta ccggtgaacc tgtttgccag ccccgtcgtc
    10081 caaatagtcg gatagataaa gtacgatata tgttcaataa aataacttag tgtattttat
    10141 gttgttatat aaatatggtt tcttgttaaa taagatgaaa tattttttaa taaagatttg
    10201 aattaaagtg taaaggagga attaattatg aagtgtaatg aatgtaacag ggttaaatac
    10261 aaccaaattt taatttggct ttgcgtttta tcttttttta gcgtattaaa tgaaatggtt
    10321 ttgaacgtct cattacctga tattgcaaat gattttaata aaccacctgc gagtacaaac
    10381 tgggtgaaca cagcctttat gttaaccttt tccattggaa cagctgtata tggaaagcta
    10441 tctgatcaat taggcatcaa aaggttactc ctatttggaa ttataataaa ttgtttcggg
    10501 tcggtaattg ggtttgttgg ccattctttc ttttccttac ttattatggc tcgttttatt
    10561 caaggggctg gtgcagctgc atttccagca ctcgtaatgg ttgtagttgc gcgctatatt
    10621 ccaaaggaaa ataggggtaa agcatttggt cttattggat cgatagtagc catgggagaa
    10681 ggagtcggtc cagcgattgg tggaatgata gcccattata ttcattggtc ctatcttcta
    10741 ctcattccta tgataacaat tatcactgtt ccgtttctta tgaaattatt aaagaaagaa
    10801 gtaaggataa aaggtcattt tgatatcaaa ggaattatac taatgtctgt aggcattgta
    10861 ttttttatgt tgtttacaac atcatatagc atttcttttc ttatcgttag cgtgctgtca
    10921 ttcctgatat ttgtaaaaca tatcaggaaa gtaacagatc cttttgttga tcccggatta
    10981 gggaaaaata taccttttat gattggagtt ctttgtgggg gaattatatt tggaacagta
    11041 gcagggtttg tctctatggt tccttatatg atgaaagatg ttcaccagct aagtactgcc
    11101 gaaatcggaa gtgtaattat tttccctgga acaatgagtg tcattatttt cggctacatt
    11161 ggtgggatac ttgttgatag aagaggtcct ttatacgtgt taaacatcgg agttacattt
    11221 ctttctgtta gctttttaac tgcttccttt cttttagaaa caacatcatg gttcatgaca
    11281 attataatcg tatttgtttt aggtgggctt tcgttcacca aaacagttat atcaacaatt
    11341 gtttcaagta gcttgaaaca gcaggaagct ggtgctggaa tgagtttgct taactttacc
    11401 agctttttat cagagggaac aggtattgca attgtaggtg gtttattatc cataccctta
    11461 cttgatcaaa ggttgttacc tatggaagtt gatcagtcaa cttatctgta tagtaatttg
    11521 ttattacttt tttcaggaat cattgtcatt agttggctgg ttaccttgaa tgtatataaa
    11581 cattctcaaa gggatttcta aatcgttaag ggatcaactt tgggagagag ttcaaaattg
    11641 atcctttttt tataacagga attcaaatct ttttgttcca ttaaagggcg cgattgctga
    11701 ataaaagata cgagagacct ctcttgtatc ttttttattt tgagtggttt tgtccgttac
    11761 actagaaaac cgaaagacaa taaaaatttt attcttgctg agtctggctt tcggtaagct
    11821 agacaaaacg gacaaaataa aaattggcaa gggtttaaag gtggagattt tttgagtgat
    11881 cttctcaaaa aatactacct gtcccttgct gatttttaaa cgagcacgag agcaaaaccc
    11941 ccctttgctg aggtggcaga gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga
    12001 aaggtcttaa aggttttatg gttttggtcg gcactgccga cagcctcgca gagcacacac
    12061 tttatgaata taaagtatag tgtgttatac tttacttgga agtggttgcc ggaaagagcg
    12121 aaaatgcctc acatttgtgc cacctaaaaa ggagcgattt acatatgagt tatgcagttt
    12181 gtagaatgca aaaagtgaaa tcagctggac taaaaggcat gcaatttcat aatcaaagag
    12241 agcgaaaaag tagaacgaat gatgatattg accatgagcg aacacgtgaa aattatgatt
    12301 tgaaaaatga taaaaatatt gattacaacg aacgtgtcaa agaaattatt gaatcacaaa
    12361 aaacaggtac aagaaaaacg aggaaagatg ctgttcttgt aaatgagttg ctagtaacat
    12421 ctgaccgaga tttttttgag caactggatc caggagaaca aaaacgattt tttgaggaaa
    12481 gttataaatt attttccgaa cgatatggca agcaaaatat tgcttatgca acagttcata
    12541 atgatgagca aacccctcac atgcatttag gtgttgtgcc tatgcgtgat ggaaaactgc
    12601 aaggaaaaaa tgtgtttaat cgtcaagaac tgttatggct acaagataaa ttccccgagc
    12661 atatgaaaaa acagggtttt gagttgaagc gtggtgaacg tggctctgac cgtaaacata
    12721 ttgagacagc taaatttaaa aaacaaactt tggaaaaaga gattgatttt ctagaaaaaa
    12781 atttagcagt taaaaaagat gaatggactg cttatagcga taaagttaaa tcagatttag
    12841 aagtaccagc gaaacgacac atgaaaagtg ttgaagtgcc aacgggtgaa aagtccatgt
    12901 ttggtttggg aaaagaaata atgaaaacag aaaagaaacc aaccaaaaat gttgttatat
    12961 cggagcgtga ttataaaaac ttagtgactg ctgcgagaga taacgatagg ttaaaacagc
    13021 atgttagaaa tctcatgagt actgatatgg cgagagaata taaaaaatta agtaaagaac
    13081 atgggcaagt taaagaaaaa tatagtggtc ttgtagagcg atttaatgaa aatgtaaatg
    13141 attataatga gttgcttgaa gaaaacaagt ctttaaagtc taaaataagc gatttaaagc
    13201 gtgatgtgag tttaatctat gaaagcacta aggaattcct taaggaacgt acagacggct
    13261 taaaagcctt taaaaacgtt tttaaggggt ttgtagacaa ggtaaaggat aaaacagcac
    13321 aattccaaga aaaacacgat ttagaaccta aaaagaacga atttgaacta actcataacc
    13381 gagaggtaaa aaaagaacga agtcgagatc agggaatgag tttataaaat aa
//
LOCUS       DACGLI010000073        13424 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.075, whole genome shotgun sequence.
ACCESSION   DACGLI010000073 DACGLI010000000
VERSION     DACGLI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.075"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            79..1125
                     /locus_tag="IXT22_002492"
     CDS             79..1125
                     /locus_tag="IXT22_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4863818.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="IXT22_002493"
     CDS             1474..2106
                     /locus_tag="IXT22_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAQ4863819.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2694..4133
                     /locus_tag="IXT22_002494"
     CDS             2694..4133
                     /locus_tag="IXT22_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4863820.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4428..4646
                     /locus_tag="IXT22_002495"
                     /pseudo
     CDS             4428..4646
                     /locus_tag="IXT22_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4895..5110
                     /locus_tag="IXT22_002496"
     CDS             4895..5110
                     /locus_tag="IXT22_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863821.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5327..5583)
                     /locus_tag="IXT22_002497"
                     /pseudo
     CDS             complement(5327..5583)
                     /locus_tag="IXT22_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(5770..6681)
                     /locus_tag="IXT22_002498"
     CDS             complement(5770..6681)
                     /locus_tag="IXT22_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4863822.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6700..7704)
                     /locus_tag="IXT22_002499"
     CDS             complement(6700..7704)
                     /locus_tag="IXT22_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4863823.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7701..9824)
                     /locus_tag="IXT22_002500"
     CDS             complement(7701..9824)
                     /locus_tag="IXT22_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4863824.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9829..12276)
                     /locus_tag="IXT22_002501"
     CDS             complement(9829..12276)
                     /locus_tag="IXT22_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4863825.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12263..12652)
                     /locus_tag="IXT22_002502"
     CDS             complement(12263..12652)
                     /locus_tag="IXT22_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4863826.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12712..13215)
                     /locus_tag="IXT22_002503"
     CDS             complement(12712..13215)
                     /locus_tag="IXT22_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4863827.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13228..13389)
                     /locus_tag="IXT22_002504"
     CDS             complement(13228..13389)
                     /locus_tag="IXT22_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863828.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4107 a         2645 c         2458 g         4214 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctaacaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2161 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2221 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2281 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2341 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2401 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2461 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2521 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     2581 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     2641 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     2701 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     2761 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     2821 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     2881 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     2941 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3001 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3061 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3121 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3181 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3241 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3301 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3361 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3421 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3481 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3541 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     3601 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     3661 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     3721 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     3781 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     3841 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     3901 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     3961 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4021 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4081 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4141 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4201 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4261 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4321 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4381 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4441 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4501 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4561 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     4621 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     4681 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     4741 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     4801 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     4861 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     4921 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     4981 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5041 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5101 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5161 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5221 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5281 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5341 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5401 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5461 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5521 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     5581 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     5641 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     5701 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     5761 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     5821 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     5881 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     5941 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6001 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6061 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6121 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6181 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6241 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6301 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6361 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6421 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6481 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6541 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     6601 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     6661 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     6721 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     6781 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     6841 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     6901 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     6961 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7021 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7081 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7141 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7201 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7261 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7321 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7381 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7441 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7501 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7561 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     7621 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     7681 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     7741 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     7801 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     7861 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     7921 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     7981 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8041 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8101 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8161 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8221 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8281 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8341 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8401 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8461 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8521 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     8581 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     8641 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     8701 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     8761 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     8821 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     8881 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     8941 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9001 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9061 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9121 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9181 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9241 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9301 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9361 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9421 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9481 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9541 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
     9601 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
     9661 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
     9721 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
     9781 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
     9841 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
     9901 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
     9961 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10021 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10081 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10141 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10201 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10261 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10321 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10381 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10441 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10501 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10561 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    10621 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    10681 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    10741 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    10801 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    10861 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaatccttga ccccttgtga
    10921 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    10981 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11041 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11101 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11161 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11221 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11281 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11341 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11401 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11461 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11521 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    11581 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    11641 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    11701 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    11761 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    11821 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    11881 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    11941 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12001 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12061 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12121 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12181 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12241 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12301 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12361 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12421 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12481 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12541 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    12601 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    12661 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    12721 atactcaaaa acacctcgac tcgttaccaa ataattgcct ccaatctcca agtctctacc
    12781 acacgcatca aaatcaatat acgtcttcaa gtgttctggt acttctccaa aatcaccagc
    12841 ttctacaatc aagaaatatg ctacatcact catatcatcg caatctggat aatagataat
    12901 atcatccaca tgctctacca tctcctcaaa agaattgaag aaagcatgtt gaatctcaga
    12961 agcaacttca ccaactggcg ttccttcaag ttcctccgct aagccacaca accgattaat
    13021 ttcctcaatt ggcgtatact catcaatctc aaagggaagt tcataatcat gaattgcata
    13081 ttcctcgtat tcgtcattta acccaattcg ttctttcact tcatcaaaat cgacaggtgg
    13141 ggtaaaccac gcccccacca attcaccttc gttatatttc ccgaggttcg caatataaac
    13201 acgcatctgt tccatcgtgc ttccccctta cgcaccgaca attcggttaa acaaactgag
    13261 taagacatcc ttcaccccag aagcattaaa gaccaatccg accgcaatca aagcaatcac
    13321 caaaaagcca atcagtttgg aaaactcccg cttaaatcct aaaaacaaac caatgaccac
    13381 aattgccagt aagactaagg attgggcatt ggttaaaaac catt
//
LOCUS       DACGLI010000074        13085 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.077, whole genome shotgun sequence.
ACCESSION   DACGLI010000074 DACGLI010000000
VERSION     DACGLI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.077"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(79..2199)
                     /locus_tag="IXT22_002505"
     CDS             complement(79..2199)
                     /locus_tag="IXT22_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4863829.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2429..3607
                     /locus_tag="IXT22_002506"
     CDS             2429..3607
                     /locus_tag="IXT22_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAQ4863830.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3623..4381
                     /gene="aroD"
                     /locus_tag="IXT22_002507"
     CDS             3623..4381
                     /gene="aroD"
                     /locus_tag="IXT22_002507"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAQ4863831.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4404..4889
                     /gene="ybaK"
                     /locus_tag="IXT22_002508"
     CDS             4404..4889
                     /gene="ybaK"
                     /locus_tag="IXT22_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAQ4863832.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4960..6213)
                     /locus_tag="IXT22_002509"
     CDS             complement(4960..6213)
                     /locus_tag="IXT22_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863833.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6329..7678
                     /gene="gdhA"
                     /locus_tag="IXT22_002510"
     CDS             6329..7678
                     /gene="gdhA"
                     /locus_tag="IXT22_002510"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAQ4863834.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7790..9136
                     /locus_tag="IXT22_002511"
     CDS             7790..9136
                     /locus_tag="IXT22_002511"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAQ4863835.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9444..9830)
                     /locus_tag="IXT22_002512"
     CDS             complement(9444..9830)
                     /locus_tag="IXT22_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4863836.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            10709..10921
                     /locus_tag="IXT22_002513"
     CDS             10709..10921
                     /locus_tag="IXT22_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863837.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11199..12998)
                     /locus_tag="IXT22_002514"
     CDS             complement(11199..12998)
                     /locus_tag="IXT22_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4863838.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4291 a         2353 c         2577 g         3864 t
ORIGIN      
        1 ttattctaag atttctcttt accaacatca tttgacaaag agcctaattt tgtcgctgct
       61 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
      121 cgtttgcgtt ttataaagat caacagttga ttgtcccttg tgttcactaa agacactagt
      181 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
      241 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
      301 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
      361 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
      421 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
      481 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
      541 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
      601 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
      661 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
      721 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
      781 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
      841 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
      901 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
      961 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     1021 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     1081 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     1141 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     1201 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     1261 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     1321 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcaagctgga gaccattctc
     1381 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     1441 attttttcct ttagcgagcc cgaacaaatc atcatttggt gctgcataat gttcttttac
     1501 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     1561 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     1621 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     1681 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     1741 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     1801 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     1861 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     1921 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     1981 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     2041 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     2101 taaataggca aaaatcgttt tcaaccaaag taaaacaact agtaaagaaa aaaatccgag
     2161 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     2221 tcttaatcac agaagtgtca tgaaaccatg ttacacagct cacttattct catttatttt
     2281 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     2341 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     2401 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     2461 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     2521 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     2581 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     2641 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     2701 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     2761 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     2821 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcgtag gaggctatga
     2881 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     2941 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     3001 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     3061 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     3121 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     3181 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     3241 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     3301 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     3361 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     3421 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     3481 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     3541 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     3601 ccattagaag gagcgatgca gaatggtttg ggtaaaggga ttgaatatag gaagcggtag
     3661 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     3721 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     3781 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     3841 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     3901 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     3961 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     4021 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
     4081 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
     4141 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
     4201 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggctgg
     4261 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
     4321 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
     4381 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
     4441 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
     4501 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcat atatttaaaa
     4561 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
     4621 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
     4681 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
     4741 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
     4801 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
     4861 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
     4921 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
     4981 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
     5041 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
     5101 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
     5161 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
     5221 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
     5281 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
     5341 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
     5401 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
     5461 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
     5521 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
     5581 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
     5641 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
     5701 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
     5761 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
     5821 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
     5881 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
     5941 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
     6001 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
     6061 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
     6121 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
     6181 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
     6241 atctgaagaa agaaaacaga aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga
     6301 gggaagataa gcaaaggagc gtggaacgat gacaaacgca acagaatatg ttcaagcaat
     6361 tcaagaaaag ctacatcaaa aggatcaagg gcaagaagaa tttttacaag caatcgatga
     6421 attcatgccc acggttatgt cttttttgga cactcatccc gaatatatcg aaaagaatat
     6481 cttagaactt ttaacggaac cagaaagagt tattcaattt cgagtgcctt ggcaagatga
     6541 tgaaggaaac tggcgagtaa atagagggta ccgtatccaa tacaactcag ctatcggccc
     6601 ttataaaggt ggattgcgct tccatcctag tgtcaatcta agtatcttga aatttttggc
     6661 ttttgaacag attttcaaga atagtttaac cggtctgcca atcggtggag gaaaaggcgg
     6721 aagtgacttc gatcctaaag gaaaatctga taatgagatc atgcgttttt gtcaaagttt
     6781 catgctggaa ttgtcaaaac atatcggccc atcgattgat gttcctgcgg gagatatcgg
     6841 tgtaggagct agagaaatcg gctatttgtt cggcgaatat aaacgattga aaaaatatga
     6901 tactggtgtg ttgacaggta aacctttgga tttttgggga agtaagatac gtacggaagc
     6961 tactggttat ggattagtgt attatgtcaa acatctattg aacgaagaaa aagattcatt
     7021 taatcaaaaa acagtttttg tttccggaag cgggaatgta gccatttatg caatcgaaaa
     7081 agtgcaagag ctaggcggga aagttgttac atgttcagat tctagcgggt acatctatga
     7141 tccagaagga atagatgtga aactattgaa agaagtcaaa gaaatcaata gacaacgttt
     7201 gacggaatac gcaaaccaac gtccttctgc tatttatcat gctggagaat ctgtttggac
     7261 attgaaagaa aaagcggata tcgctttgcc atgtgctact caaaatgaaa tagacgaaag
     7321 cttggccgaa atcttagtag aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc
     7381 atgtacagta aaagctgttt ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa
     7441 agctgctaat gctggaggag tagcagtatc tgctttagaa atgagtcaga acgcccagcg
     7501 attgacttgg gaaagagagc aagtggatga gcagctggat caaatcatgg aaacgattta
     7561 ccatacgtgt cgccaaacag cagccgagta cggcgacgaa aaaaatctgc ttcttggagc
     7621 aaatgttgct ggatttgaaa aagttgccaa agcaatggca gcagaaggtt tagtttgaaa
     7681 aatgaaactt tcttggaaat attgtcagca ttttgtttat ttgcttgaaa aataataaaa
     7741 aaaaacgtaa agtattacct gtagagtaaa cctataagga ggagaacaaa tggcacacat
     7801 tcattttgac tattcaaaag tagcaccgtt tgtcaacgaa caagagttag ggtacatgca
     7861 aagccaagta acagcagccc acaacgaatt acgggaaggt actggcgcag gaagcgactt
     7921 ccgcggctgg atcgatttac caacgaacta tgacaaagaa gaatttgcac gtatcaaaga
     7981 agcagctaaa aaaatccaat ctgattctga agtattagtt gttatcggta tcggtggttc
     8041 ttatttaggc gctcgtgcag cgatcgactt cttgaatcac acattcttca atttattaga
     8101 tagcaacaca agaaaagcac cacaaatctt ctttgccgga aattcaatca gctcaacata
     8161 tattgctgac ttgatcgaag taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa
     8221 atctggaaca actactgaac cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa
     8281 gaaatatgga caagaagaag caaacaaacg tatctacgct acaacagata aagcaaaagg
     8341 tgcagttaaa gtagaagcag atgcagaagg ttgggaaact ttcgtgattc ctgatgacat
     8401 cggcggacgt ttctctgtat taactgctgt tggtttgtta ccaatcgctg ttagtggtgc
     8461 agatatcgat gcattgatgc aaggtgccgc tgatgcaagc aaagcatact caagcgacaa
     8521 actagaagaa aacgaagctt accaatacgc agcaatgcgc aacattcttt accgtaaagg
     8581 caaagtaact gagttgttga tcaactatga accaggaatg caatacttct cagaatggtg
     8641 gaaacaattg tatggtgaat ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc
     8701 aaacttctca actgatttgc actctttagg acaattcatc caagaaggac gtcgcaatat
     8761 ttttgaaaca gttgtgaagg ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc
     8821 agaagattta gacggtctag gctacttgca aggaaaagaa gtggacttcg taaatacaaa
     8881 agcatttgaa ggaacattgc ttgctcatac agacggtgac gtgcctaact tgctagtcaa
     8941 aattccagaa atggatgctt atacattggg ttatacaatg tacttctttg aaattgctgt
     9001 aggtatttca ggttacttga atggaatcaa cccattcgac caaccaggtg tagaagctta
     9061 caagaaaaac atgttcgcac ttctaggcaa accgggcttt gaagatcttg ctaaagaatt
     9121 gaacgaacgc ctgtaagata agggtttttc gctagattta aataatcagt gatagaaaca
     9181 tgttcgcttt aaaatgaaaa ctggtaccca tttaggtact caaacatact gcatcgttta
     9241 ttcagaataa ggggctgtga caagacgttt gtcacagtcc cttgtttgta tagaaatcga
     9301 ttgattgcct tgctctttag tttgttttag gactttaaga acagtgaggc tgacttcgaa
     9361 ggttaattct gtttttttgt tttctagaat cagtaagcaa aaaagcactc acttcgagtg
     9421 cttttttgcg atatattctt agcttaagat aggcctaatt tttcttttac agatgagggt
     9481 accttatcgc tggtaattac ttttttctct atgatccgct tttcgcttgc tttcaactgc
     9541 aagatcgttc cttcggtgta agcagaacca ttggcagagt caccagaagt aatgacatcg
     9601 aaatctaact gtcttttttc accgttttca gcataagcat ctacgttgta tttaaaacct
     9661 cttccaatta cttccccatt atctgctttg atatcagttt ctgcaggcat tggagctttg
     9721 actaccgcat aataatcttt acctacataa gtagactgat agtagtccca acctttccat
     9781 cctataaaag caatcaatat gataacgatc aaccctaaaa tttttttcat gaaagatctc
     9841 cttttttatt tttattatat taaatattat acagataata acggaatatt atcatcgaaa
     9901 cagctaacaa aattgtcata aaaaacgaga tggttgatat tagaacttgt gtttttgttt
     9961 aggtctagag ataaagagag acaatttcca aatatatgta atgaatacaa aaagacgttt
    10021 gtcgcggatt accgttacaa acgtctttta ttgattttcc gagatctcat cagtcgccat
    10081 ttggaatggt tcactcctta tctagattcg tttaatgctc ggactgcttg ttcgattgta
    10141 ataccaaacg caacgttatt ttcgttttgt gcatcaatcg ccataaaacg gttagaagtt
    10201 gtatcaaaag ctacgcggta ttgcatattt gtttttgtaa acgtcataaa attcatctcc
    10261 tttgtaatgt aatttagttc ttgaaagttt cctttaaact ttcgaactta taccaagttt
    10321 agcatcgtac gttttttgat gcaattaaaa agcatttatc attttcctta tttatttttt
    10381 cttaaatggt ttagctattt tcttttaatc cgataagtag cccaatcatc aaggttacaa
    10441 atactattgc ttgaatataa atcatatgct cacctcttta taaataactt agcaatataa
    10501 agaaaaaaac gcacgaacaa cataggaata taaacaaacg tttttgtcac aacgtctaag
    10561 atcgtgttaa aaaatagtta tctaaaaagc agaaagatac tcaaaataaa aaataaaaaa
    10621 atgaataaaa acgttttcaa atacaaggta atttgttatt ataaaataaa gaaaaaacaa
    10681 aataaaaata aagaaaagag ggaatgaaat ggtaaaagca gaagtaggaa gatcttatat
    10741 atgcaaaccg atcggagtat ctcatgaact aatcggctgt attgaacgta catatatcaa
    10801 cacggctgtc gtgtatgttg aaagttatga ccaacgagac tatcaactta tcaatgaaag
    10861 caagtatcgc atgctcgtaa aattctgtga tattagcgca cctactgaat tggtttctta
    10921 aacagtattt ttgagaattc gcaagaactc ccttataata taaataaaga cagaagggag
    10981 cgagaagata tgccaaaaag aaaaagttca gggaaaatgg gaattattct tgcagtgatc
    11041 tctgcaattc ctgctatttt agctattgtt cgtgcgatga aggaatcaag agaaagttaa
    11101 gcacacatta tgagcgtcaa acaaaaaacg catatacctg cggtggcagg ttatgcgttt
    11161 tttgttgtat aaagactttt ttcattaacg atttttgatt agccgactcc caaaacaaaa
    11221 tttagcagtt tatctgaata agtgatttct tcatctgttt gtttcacact ttcatttagt
    11281 agtcccatct catcggttat gataccatcc acaccataaa acatcatgcg actcatggca
    11341 tctgaatcgt tgattgtcca tacatatact tcttttccgt cttggtgggc agaattaatg
    11401 aagttacggt tgatcgtact atattccatt gtcagaaaat cagcaggcgt cacagggggc
    11461 ccaacaatat tgaaaggtaa gatgtagccc acataaaagt ttggttctgc ttcttttaaa
    11521 tctgaaacgg tttggtacgt caaactttgc aaaatatgat ggttctctaa gataactttg
    11581 cggtatttat ggacaaatcg ttcgacaagg tcatccgaat cttttttaga ggtcttgatc
    11641 tcaataagta atttttggtt tagcttatgt gctttttcca aataagaatc aaaagaacaa
    11701 acaggggctt gcactccgtt ttcagtaact gtaagatttg tcaattcttt caatgtaaga
    11761 tcctgtggtg ttccatttac ccctgttaag tgacgaagat ttgcatcatg catcactacg
    11821 aaatgaccat cttttgtttc ctgaacatcc atctctacat aatcaggatg atagtctctg
    11881 cttgtttttt caagtgcttc taaagtattt tgcgccccat tttgggtact cacacctctg
    11941 tgagagacag tcactggttt tgtctgaaca gctgaagtca gataatccat attgtaaaga
    12001 cagacgccaa taccgaaaaa aactgcaaaa agagtcaaac cagtgttttt cagcgcagag
    12061 aaacgcaagt tgggggcttg tgggataaac cacttaggga tctcaggcaa gaagccttcg
    12121 tcatccatga aatcaacaat gatataaaaa atccctacgg tagacatcac gatattgaat
    12181 aataaaatcc cttgtaaaag cgtcatagca aacacagcgc tgatcaatgc atagtctggg
    12241 aaaaattgtt caaccatact ttgtgccaaa ataacaacga tatatcctaa agaagaaagg
    12301 agtaaaatcg taccgccaat cacaataaat tggcccgtga tggccaaaag acgcgatttg
    12361 gtcaatgacc agctttcccg aatggctgct cgaaaagaac gatctcgtag aatcatttcc
    12421 ggtaaagcaa aaatcagtcg aatcccaata tagccaagga aaatataaac gagtaaaaag
    12481 gaactgacga tgatccaacg attagcaaaa ataaaatcca taatgaaagc ggggattttt
    12541 atttttgaca gtagatcaga attaaaactt aatccgctga tcggtagaat caataaaaaa
    12601 taagcaagga aaaacaaaaa agtaatgggt ctcactttct tcagctgaag tatcgtcaag
    12661 tgtaagagtt gcttcaaaga gattggttct ttctttttaa taaaaaaaac actcatcaaa
    12721 agaaaagtaa attcgaaata aactaacagt aaaatcgtca tcaaaactac gattaacgag
    12781 agtagaaccc caggatgttg agaaaaaatt gaaggaatat tgtcataaga caaatagtca
    12841 attgcccctc ggtgtaaaat aaaacgggtc gtactgctca ataagggtaa acaaataaat
    12901 aaaataaagc catgcatcag caagacatca cggaaataag cttgtgttcc ttttaaaaag
    12961 tcccaagcat tacctaagct acgtttcaaa taattcatcc tatcacctgc tcttcacatt
    13021 gtagcgcaaa tctaatgaaa aaggaaaggg tgcagtgtgt tttgcagacc ctttcccaga
    13081 tttaa
//
LOCUS       DACGLI010000075        12980 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.078, whole genome shotgun sequence.
ACCESSION   DACGLI010000075 DACGLI010000000
VERSION     DACGLI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.078"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(63..1172)
                     /gene="rpoD"
                     /locus_tag="IXT22_002515"
     CDS             complement(63..1172)
                     /gene="rpoD"
                     /locus_tag="IXT22_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAQ4863839.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1196..3037)
                     /locus_tag="IXT22_002516"
     CDS             complement(1196..3037)
                     /locus_tag="IXT22_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAQ4863840.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3219..5612)
                     /locus_tag="IXT22_002517"
     CDS             complement(3219..5612)
                     /locus_tag="IXT22_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4863841.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5719..6579)
                     /locus_tag="IXT22_002518"
     CDS             complement(5719..6579)
                     /locus_tag="IXT22_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAQ4863842.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6638..7270)
                     /locus_tag="IXT22_002519"
     CDS             complement(6638..7270)
                     /locus_tag="IXT22_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAQ4863843.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            7479..8198
                     /locus_tag="IXT22_002520"
     CDS             7479..8198
                     /locus_tag="IXT22_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863844.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            8224..10815
                     /gene="mprF"
                     /locus_tag="IXT22_002521"
     CDS             8224..10815
                     /gene="mprF"
                     /locus_tag="IXT22_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4863845.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11003..12190)
                     /gene="tuf"
                     /locus_tag="IXT22_002522"
     CDS             complement(11003..12190)
                     /gene="tuf"
                     /locus_tag="IXT22_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4863846.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12558..12914
                     /locus_tag="IXT22_002523"
     CDS             12558..12914
                     /locus_tag="IXT22_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4863847.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         3723 a         2718 c         2311 g         4228 t
ORIGIN      
        1 ttttttcttt taaaataaac caaacagttt tactgatttc tcttctggtc aatagtccac
       61 gcttattcta agaaatcttt taattgtttt gaacgagaag gatggcgcaa ttttcttaat
      121 gctttagcct cgatctgacg aatacgttcc cgagtaacac caaacacttt ccctacttct
      181 tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta agcgaaggac attctcttcc
      241 cgatcagtca atgtatctag tacatcttcc aattgttctt ttagtaactc ataagctgcg
      301 tgttctgctg gacttgttgc ttcctggtct tctatgaaat cacctaagtg agagtcatct
      361 tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg cgattttcaa gatttctcgg
      421 actttttctg ttggaagatc catttccgca ccgatttctt ctggcgtagg ttctcttcca
      481 aggtcttgca gcaattgacg ttggatacgt atcaatttat taattgtttc aaccatatga
      541 actggaatac ggatcgtacg tgcttggtca gcgattgctc gagtgatggc ttgacgaatc
      601 caccatgtag cataggttga aaacttaaat cctttgcggt agtcaaattt ttcaactgcc
      661 ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga actgcatgcc tcgtcctaca
      721 taacgtttag cgatacttac tactaaacga aggtttgctt ctgccagacg ctgtttcgct
      781 tcttggtcgc cttcttcgat tttcaatgct aacgctactt cttcttccgc agttaaaagg
      841 gagacacggc caatttcttt cagatacata cgaaccgggt cattgatttt tacaccggtt
      901 ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt tctcagcact cttcaagctg
      961 tgaattgatg gatcaccatt ttcatccacc acactgatac ctgcgtcttc aatcttttgg
     1021 atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg tagcaagctg attggataaa
     1081 tcatcatata caacttgtcg tttgggtttg ttttctttga tgaaagctgc tactgctgct
     1141 tcatacgttt ttttatctgt tccatttgcc ataaaagaag gccccccttg agtagctatt
     1201 tggcttgttt taactgtttc gttaaattga tgatttcaat cgtcaattca agctcaagct
     1261 gtttgtttcc agttcgtctg gcttcttgct gcatttgttt ttttaatgtt atttcatcag
     1321 ctaagccaga tttgctgatc acatctagca agtcttggat ttctcgtggc gaactttctt
     1381 ctgccaccgg taaatattcg atttccacca ccaaccgcct taaattttca tcttgcaaaa
     1441 agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga gacatatgca tcgaataaaa
     1501 aataaacttc tgcatatgca tcatgaataa actgaaattc tcgttctttt aaaatattac
     1561 ggacagaaac ttctttaaat gcacgatata atagaatctg ctctgccttt tctacttgcg
     1621 tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac ctgagtgtgt tgactttcct
     1681 gaggttcttg acgattttgc tgatttgtcc ttcgaagatc gcgcagttgt ttttgtatcg
     1741 tctctctgcc gatctgaaac tctgttgaca gttgagatag atacatatct tgttcgattg
     1801 gtgaaacaac tcggctaagt tcaactagta attcttcgag gtattcgatc ttgtcttttt
     1861 cattatctaa atttttccct tgttttaaat aacgtgattt aaaagtaaag actgtttcgc
     1921 gcccatgagc cactaattct tggaaagatg cttctccata cttacggaga tattcatcag
     1981 gatcaagctt ttctggaacg actacgacag aaagtgctaa tcgactgttt tgccgaagca
     2041 attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc tccgtcatag caaaagacca
     2101 attctttcgt cagcttttcc atttgttgga tctgttgagc tgttagactt gtccccatag
     2161 aagctaatcc agttttgata ccagcctgcc atgcagcaat cacatccata aacccttcga
     2221 acaacaaaat ttctccgttt ttccggatat cgcttcttgc tttatcaaga ttaaataaaa
     2281 cttgtctttt attgaacagt tctgtttctg gactattcaa gtatttgggc tgatcttttt
     2341 cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc gatcgtctgg ccttgagaat
     2401 tacgaagtgg aaacatcact ctttgataaa aacgatcaga catacggcca tcatcatgcg
     2461 tgacaaacaa tccagagcgt tctaacaatt catttgaaat tgattcattc ttgaatactt
     2521 gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt gaattcttca attaattcta
     2581 aagacaaccc acgactttgc aaatattcta aagctggctg tccagctttt gtatgcaata
     2641 gcatgtgatg atagatttcc gctgcttttt catgagcagc aatcagtttc cccgtagcag
     2701 attcaggatt ttggacagct atagtacgct gacgccattg atcttctaac ggtatctgtt
     2761 cgaagtctgc cacttttacc actgcttctg gaaaacttag accttctagt tcttgaagaa
     2821 aagtaaacac gtttccgcct ttaccacaac caaagcaatg aaaaatctgc ttgtcttctg
     2881 caacagaaaa agacggtgta cgttcttcat gaaaaggaca cagccccaag taatttttac
     2941 cagacttttt caactggaca tattgtccaa tcacctcaac gatattcgtt tgactgcgta
     3001 ctgtttcgat aacctcttga ggaatccgtt gagccatttt ttcaccccct gctctattga
     3061 tatcttttgg gtttaacaga agatatttca ggagaataac cggtaaaaaa tcgcactaac
     3121 tgaaatcagt gcgattttaa aggacacaat tatacatgtt tgattgtatc atatttcatt
     3181 gctttttcaa gtataacaca tttctatctc attaagcatc aatttgctac tcttttcagt
     3241 aactgatttt gaatatcagc cttccagtac aatactcgaa gaacaatatt tacgagcatg
     3301 aatacaaaga agtatcctac gctctctccc aaccctaagt ttacttccaa aattccatgg
     3361 aacagcattg cagctacata tatccctacg atcgtcgtta ctgctaggaa gatgcgcaat
     3421 gggttgaagg gataacaagc ttttacaact gccatgcaac tgatcccaat cagcaagtaa
     3481 tacatcaaag tagtagtttc agcatttccc catgcgaatg tttttccaag tagatacacc
     3541 gcaatgatat tcactactac aagcaaggca tttggtaaag cattaataag tgctgtaggc
     3601 aaataacggt aagtgatttt tcttttatct tgttcaaaag ataaaaagaa ggaaggatac
     3661 ccttcaatcg ctaaatcaat cagcgtgatt tggataggga taaacggaaa tccaattgct
     3721 gtaacggcac atataatcga taaaataaat gaataaatcg ttttgataaa aaagatgcct
     3781 gagactttcg tcacattgtt gaccactcgg cgtccttcaa acaggacttc tggcaatgta
     3841 gtaaaatcag agtccaacaa taccagattc gcaatctgac gtgttgctcc atcaccttct
     3901 gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa catcattcac accgtcgcct
     3961 gtcattgcaa ccgttctgcc gctttctttc aattcattta ccagcaattt cttttgctgc
     4021 ggactcactc gtccaaaaac cgtatagcga tgagcagctt ctcgcacttc catttcttca
     4081 gtaatttgag aaagatcgac atacgcatca taattcggta atcctgcacg tctagcgata
     4141 ttggagacag taaaaggatt gtctccagaa atcactttca gatccacacc ttcctcatga
     4201 agataagcta gtgtttcttg agcgtttttt cggattggat catcgatttc aaacagagca
     4261 accggctcaa caaatgctgg tttttcttcg ttcaattgct gatttggagc gatccccaac
     4321 ataagtacgc gatagccatt cgcttgggct gtttttagac tgtccggaag ccgatcttct
     4381 tccaccaaac gttcaggcgc tcctacgtac acgactccca gttctggaaa ttccatcgcg
     4441 ccccatttgc gatcagaaga aaatgcgact ttgtttgtca catcataccg attagaaagc
     4501 tcaaaataat ctctcatagc ccgcatagtg atgttgttat cactgctttc tgccagatac
     4561 gtccccataa tttctgggat ggctttctcg tacagcggat gtagtgcttc tacccgctgg
     4621 atactcattt tcccttcagt aatggtccct gttttatcca agcataatgt atcgacatgg
     4681 gccagcgttt caattgaata catgtcttga acaaggattc gtttttttgc cagtttggtt
     4741 acccctgtcg ttaatgcaat acttattagc aataccaaac cctttggaag catgcctaac
     4801 aaagctgctg cagatgcaat aacagaaatt ttgatagaag catcgcggat gaacagtgct
     4861 tccaaaaata gtatgatccc caaaggaata atcacgaaac tagtgaattt ggatactttg
     4921 cgaatcgaat ctacaagttc agaacgaata gctttgtgag tctttgcctc gctagtcaag
     4981 cggacagcat aattatctgc acctactcgg ataacttcag ccatgacaga accgcttgtc
     5041 aaaaagcttc cagaaagcaa ttcagctcca gtttctttga caatcaaatc agattcgcct
     5101 gtcaaaagag cttcatttgc ttctgcccgt ccagatataa cctgtaaatc ggctggtatc
     5161 tgttctcctg ctccgatttt taccaaatct cctaatacca gctctttagt agaaatcgat
     5221 tgttctttac cgtcccggat cactagtact tctgattggg aaacaatcga taatttccgt
     5281 acaagatttc ttgcatgtat ttcttgataa attccaataa cgatattgac gacaataatt
     5341 gctaaatacg ccatgttgga atacgcacct acaaataaca gacaaatccc aataccaaag
     5401 ttcagaaaat tgaataacgt caatatatta tcgctgaata tttgttttgt actttttgat
     5461 gcatcttcct ggtagtcatt ttgctggcca gaagccattt tctgaactac ctcttgctgt
     5521 gtaagtccat tcattttctt tttctccatt ttccgccaac tttcaaaaat aatcacgtgt
     5581 ttaagtctag cgtgttccaa gattaaaaac aacttgtttt tataaaattt atagaaaaac
     5641 acacgaatga ttttacaaaa aagatgccaa cctttttgtt tgaatcaccc gtgtgctgtt
     5701 tttattatca atctatcttt acttatattg ttcctccaaa cggctcatcc accaacctag
     5761 tgctgtaccg gctataaaaa gaacaggaca agctagtacc ccagcaactc ccaatcccgc
     5821 gtaatcggta ggaatgatca taatcgttga agcaaaaact acacctaaaa tgaaatggaa
     5881 tagcttgcta tatgcctttg agaaaatgta atccatgatt tttgacaatc caagaacaca
     5941 aagaatccca ccaattccga tcggcacaat cacttcaagt cgtacttctt taaatccgtc
     6001 agccatcgct ttatacaatc ccatatacac caaaaaatta gaagggctca atcctgggac
     6061 gatcataccc aaaccaatca atccgccggc aatcagccat gttccaaaat tctgatcgac
     6121 ttgcccgtca aataattgag cgccgtataa taaaaacaaa taagccagaa caaaagtaac
     6181 aaccatgatg atcacatcag aagtatctct tccttttttc cctgcttctt tccataacgc
     6241 aggaacagtt ccagcgatac atccgacaaa aaaccataat atcgttgttt catacgcacc
     6301 taataaaaaa ctgactaaaa aagaaagtag aaagatgcct gtcactccgc ctagaccaac
     6361 aggcagaaaa aacaaaacat tttctttgaa attttttgta aggtgggcta aaaaagaaat
     6421 cagccgctca tacatgccaa agacagctgc taatgcacca ccgctgactc ctggcaagat
     6481 aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac atccagtctt tggttgtgta
     6541 ccccacttct tgattttcca ttttttgcct tttttccact atttgcgcac tccttctttc
     6601 atttaatttt attcatgatt gaacatttcc tgctatttta cttaaagact ttttcatagg
     6661 tctctattat tttttcattc attttgacaa tatcaggata aaacatgtta cctccattat
     6721 gatagagata gccgccattg taaagcaagg actggatccg ccaatatcgg tattgtttcc
     6781 cttcctcatt tcctaaaagt gggctcagca catctttaga atacgcttct gctaattcta
     6841 ctgtgttttc tccgccatga ttttttacat aggcaatata atctttccca aaattatatg
     6901 cttggacagc tgtccataaa tcgcatcctt gtttctttgc ttctactatc atttccgcca
     6961 aatatttgac accttgatca atactgtcag ctggattatc aatgatctca gcttctccat
     7021 gcagactttc cgagctccgc atgagatctg tcccttttcc ttttgattcg gtcaatatta
     7081 tcgccttgat caaattctcg tagttttcca tatgataatt ttttgcagct gttgttattt
     7141 ctatttgata gctttccact cgttttaccg aacgataagt tcttcctcct aaaaacaaca
     7201 ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat acggataata gataatcgtt
     7261 ttcgcttcat ttcatcacct agttattttg acatcttttt ttatcttact atttctttat
     7321 cttcttggct atttcttcct tgatttctgt gtacgcctta agaaaaaatg aattttcctg
     7381 tattttttgt catcttacga aaatgatcgt tgtttttcag taaaaacaat tgcccaatga
     7441 ctgatataat cgttatactt tacacagtag gtgattatgt gaaaaaagaa aagaaatatg
     7501 caaaaatgcc agatgggagc gaaatttact atgaaaagag cggtcaaggc ttccctctct
     7561 ttttactgca tggcaatgac ggcagcggcc gctttttttc agaacaggtc cctgtactcg
     7621 aacgctacta taccgtgtat ctagtagata gccgaggaca tggtcgttcg acaaacgaag
     7681 catctatgtt gaattttcag ttaatggccg aggatctgaa tacgatcatg ttgctggaaa
     7741 aaatcgatca ggcagatttt cttggattta gtgatggagc aaatctagca ctggtatttg
     7801 ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa ttctggaaac acgcttgtta
     7861 aaggcgttcg tttttctgcc agagtcatca gtaatattca ttatgcatgg gtatggttac
     7921 tctctttatt tcgcccaagt cttcgcaaaa atcttttagt tatcaaactt ttgctgcatg
     7981 acatcgggct tacagaaaat gatttaaaaa aaatcaactc ccccactttg atcatcgtgg
     8041 gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat agctaaaact ataccaaaag
     8101 cttcctttgt gcttgtgaaa gaacaaggac atgaattagc tagaaaagat cctgaacgct
     8161 tcaatcgaga agttcttcaa tttctttctg aaacataact attaggaata gaaggtgatt
     8221 tatttgttaa aaaataccat acaatggctg aaaaaccacc taggactgtt caaaacaatc
     8281 tttttgattt ctgtcattgt cattattgtc ggtgaattga tgtccatcgg taaaactcta
     8341 tctatccagc aattaggaga aacgtttgcc actatacctg tatggaaaag cggacttatg
     8401 ctgttgattg gtcttgtctc tgtgttacct atgattggtt atgatattat tttgaatcgg
     8461 atgcttgaac aaaagcagaa tcctcgttac ttgtttgaga caagctggct gatcaataca
     8521 atcaacaata ttgccggttt cggcgggttt gttagtgtgg ggcttcgctc tgaactatat
     8581 ggacaaaaga aagagagcag aaacgtgatc caagcattat cgaaagtttt cttgtttttg
     8641 atggctggac tttctattta cagtctgctt tcttttttac ttgtagtctt cacgccagtt
     8701 gctccttttt tgaagcaata ttggatatgg ttgatcggcg gcggtctata ttttcctgtc
     8761 gtctttttat ttactacttt caaaaagaaa ggattccttg gtggtacctc acttaaaact
     8821 caaggacagc tattgctagt ttcattgttg gaatggaccg gtgtcctgtt tagtttcctt
     8881 tctgttggtt atttaatgga aatccggatt gatctgtggc aaacaattcc gttattcatt
     8941 gctgcttcag tgataggaat cgtgtctatg attccaggag aaattgggag tttcgatgta
     9001 atgatgatta tcgggttgtc cgctattggt gtgccaagag aaatagtcgt tgtgtggatc
     9061 ttgctctatc gcctgttcta ctacatcatt ccgtttttga ttggaatcgt ctttttcttc
     9121 aaaaatatcg gttccacttt tgatcagcgt tattctggta tccctaaaca attagcaaca
     9181 gaaattgcgc ataaaatcgt ggttgtctta ttatactttt ctggaatcat gctagtactt
     9241 tctgccacta tcccgcaagc ttttacagag tttcgctggc ttcatagttt gaacccattg
     9301 aaatttcatt ttattatcca atttcctagt atactattgg gatttctttt aatcattatg
     9361 ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc ctacaatctt cttgattgtt
     9421 ctagctttac tttatgtttt attaagtgat tttagtttca caccggtggt tttcttgtct
     9481 attctgcttc tgatcattct tgcttctaaa aacgaattat ttcgggaaca attgatctat
     9541 tcatgggagt ggcgtacgat cgatggaatc attattggtg cactgtcctt gctttacatc
     9601 gttattgggg tatacaatct gccggatttc cctcatcggc gtcaccattt tatttccttt
     9661 ttcttatttc cttctgaaaa gatttggttt tcgggattgt tggccatcat cgctgttagt
     9721 ttcatgatcg ttctatttgt tcatttcctt caaggagaaa agaaacagat tggcgaagcc
     9781 tttaatgaag aaaaggccct gaagatcctt acaacttatg gaggaaactc cgatagtcaa
     9841 ttgatcttct taaaagataa gcggatgttt gcctatgaaa aagacggtga accaactgtt
     9901 cttctccaat tcgcttgctt caataataaa tgtattgtaa tgggtgatcc ttctggtaag
     9961 aaagaagatt ttccagaagc aatcgaagct tttatcgaag aaacagatcg actatgctat
    10021 ttaccagttt tctacgaaac aagcgaagag attgttatga ttttgcatga attcggctac
    10081 gatttcatta agatggggga agaagcttat gtagacctga atagttttac aacttcaggg
    10141 aaaaaaatga agggcactcg tgctgtcttg aatcggatcg aacgagaagg atttacattt
    10201 gatgtcttac aaccaccatt ttctactgag caaatgagta ctttcaaaaa tatctctgat
    10261 aattggttgg gttcacgaaa ggaaaaaggg ttttctttag gctttttctc tgaagattat
    10321 ctacaaagag cgcctattgc agttgtcaaa aatacccaag aagaaattgt cgcttttgca
    10381 acgatcatgc ctacttacac gaacaataaa gtaggaacga ttgatctgat gcgatatgat
    10441 cctaaaaaag caccttctgg cagtatggat ttcttgttct tgcatttgtt tgcctatatg
    10501 aaagaagaac atatccaatg gttcaattta gggatggccc ctctttcaaa tgtcggaact
    10561 tccagaaaga gttttttaca ggaaaggatt gcatacttgg tttacgagtt tggttctcat
    10621 ttttattctt tccatggatt aagagaatat aaaagcaagt acgctacaaa ctgggtctca
    10681 cgttatactc tatattctag agatagttgg attgcatatg ttatgattgc tttgctgatt
    10741 attgataatg cgccagttga gcagacacaa ggtagaataa gtggtttgaa aaaatggata
    10801 cgaagaaagt attaaaaact gcataccgat agatgaacac tctcatgatg aataaaagag
    10861 actgaagtaa aacgaaagtt catgcttcta caatctcttc ttatacaatt gaagaacaaa
    10921 gagcggtcca aacagaaatc ctgtttggac cgctctttta ttttaaacat ttttcattac
    10981 caaaatattc gagtcgcgtt tcttatgctt cgatctctgt aacgatacct gaacccactg
    11041 tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc aacagcgatt ggatggatca
    11101 agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat ttctgtatct tctggcaatg
    11161 tgattgttcc tgtaacatca gttgtgcgga agtagaattg tggacgatag ttgttgaaga
    11221 atggagtatg acgtccacct tcttcttttg tcaacacgta cacttctgct ttgaattttg
    11281 tatgtggagt aatggaacct ggtttagcaa gcacttgtcc acgttcgata tcgtcacgtt
    11341 ggatcccccg taacaacacg cctacgttat ccccagcttc cccgtaatct aacgttttac
    11401 ggaacatttc tacacctgtt acaactgctt tttgtgtttc aggtttgatc cctacgatct
    11461 ctacctcatc accgacacga acagcaccac gatcaatacg acctgaggca acagttcctc
    11521 gacctgtaat tgagaagacg tcttccactg gcaatagtaa tggtttatct gtatcacgtt
    11581 ctggtgttgg gatatattca tctactgtat ccatcaattc cataatagca gcttcagcat
    11641 ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat cacaggagtg tcatcgcctg
    11701 ggaaaccata ttcgctcaat aactcgcgaa cttccatttc taccaaatcg atcaattctt
    11761 catcatcgac taaatcaact ttgttcaaga aaacaatcag gtattttaca ccaacttggc
    11821 gtgacaataa aatgtgttca cgtgtttgag gcatcggacc gtcagttgca gaaacaacta
    11881 agattgcacc atccatttgt gctgcccctg taatcatgtt tttcacatag tccgcgtgtc
    11941 ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc atattctacg tgtgcggtat
    12001 tgatcgtaat cccacgttca cgttcttctg gagctgcatc aatactagca tagtcttgag
    12061 gatttgctag gccttttttg cctaatactg tagtgatcgc agcagttaaa gtagttttcc
    12121 catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg tttacttctg tcataatgtt
    12181 cttttgccat aatttacaaa cctcctaaat aatatagatc actgaaaaat ttcagctctc
    12241 acctttttat tatagtcttt ttttgactaa atcaaaaaga atacgtccga cttacttttt
    12301 gtaagattcg aactaagctt attatacgtc aatattggtc aaagtcaact aagagcactc
    12361 gcttgtctta tacgcgaaaa aagtaccttt tataaataaa aaaatgtgtt ttttgagaaa
    12421 aacttcaaga tagtccttaa ctttcttttg aagcaataag aacaaaatga ggaaaagttt
    12481 aaaattcagc tgttgccaac aactttcaat agacgaaatc ttctatttcg ttaataataa
    12541 ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact tgtcgtttta ggcatatttc
    12601 tcggcggaag ttttgcagct tatcattatt tttacggcgg cgaagcttat tatacaaaaa
    12661 tcacgacgaa tggcgaaatg tcagctaccc aagcagataa cggagagaaa ttcacgactt
    12721 atacctacaa gcaagcggct tataataaag atggtgaaaa aaaacaggtg acgcttcgcg
    12781 aagaaagaga acatccatta aagatgaatg cgtatcttaa actcaaagtc aatcctcgta
    12841 aaggtgtatt aagctgggaa gaaataaagg cttctgaagt gcctaaaaat gcggcagaaa
    12901 aaatcgataa ttagtaaatg gtcttaaaat tttattagat aaaaagaggc tgggacagaa
    12961 gcgtttaact ccaagaaata
//
LOCUS       DACGLI010000076        11445 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.080, whole genome shotgun sequence.
ACCESSION   DACGLI010000076 DACGLI010000000
VERSION     DACGLI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.080"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            185..1183
                     /locus_tag="IXT22_002524"
     CDS             185..1183
                     /locus_tag="IXT22_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4863848.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="IXT22_002525"
     CDS             1295..1804
                     /locus_tag="IXT22_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAQ4863849.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="IXT22_002526"
     CDS             complement(1834..2493)
                     /locus_tag="IXT22_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAQ4863850.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="IXT22_002527"
     CDS             complement(2495..3259)
                     /locus_tag="IXT22_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAQ4863851.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="IXT22_002528"
     CDS             complement(3267..3944)
                     /locus_tag="IXT22_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAQ4863852.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="IXT22_002529"
     CDS             complement(3981..5366)
                     /locus_tag="IXT22_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAQ4863853.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="IXT22_002530"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IXT22_002530"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IXT22_002531"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="IXT22_002531"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAQ4863854.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="IXT22_002532"
     CDS             6305..7162
                     /locus_tag="IXT22_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAQ4863855.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDGTEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="IXT22_002533"
     CDS             complement(7243..7578)
                     /locus_tag="IXT22_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863856.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="IXT22_002534"
     CDS             complement(7645..9015)
                     /locus_tag="IXT22_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAQ4863857.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="IXT22_002535"
     CDS             complement(9093..9629)
                     /locus_tag="IXT22_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4863858.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="IXT22_002536"
     CDS             9938..11419
                     /locus_tag="IXT22_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4863859.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRSCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         3517 a         2299 c         1855 g         3774 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatggtactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgctctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DACGLI010000077        11148 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.081, whole genome shotgun sequence.
ACCESSION   DACGLI010000077 DACGLI010000000
VERSION     DACGLI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.081"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            6..305
                     /locus_tag="IXT22_002537"
     CDS             6..305
                     /locus_tag="IXT22_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863860.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IXT22_002538"
     CDS             378..1739
                     /locus_tag="IXT22_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAQ4863861.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IXT22_002539"
     CDS             1761..2021
                     /locus_tag="IXT22_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863862.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IXT22_002540"
     CDS             2035..2787
                     /locus_tag="IXT22_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAQ4863863.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IXT22_002541"
     CDS             complement(2881..3486)
                     /locus_tag="IXT22_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4863864.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="IXT22_002542"
     CDS             complement(3542..4516)
                     /locus_tag="IXT22_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAQ4863865.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5673)
                     /locus_tag="IXT22_002543"
     CDS             complement(4894..5673)
                     /locus_tag="IXT22_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4863866.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPPDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="IXT22_002544"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="IXT22_002544"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4863867.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="IXT22_002545"
     CDS             7164..8561
                     /locus_tag="IXT22_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4863868.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="IXT22_002546"
     CDS             8642..9082
                     /locus_tag="IXT22_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4863869.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="IXT22_002547"
     CDS             9229..9555
                     /locus_tag="IXT22_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4863870.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="IXT22_002548"
     CDS             9556..10305
                     /locus_tag="IXT22_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863871.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="IXT22_002549"
     CDS             complement(10331..10741)
                     /locus_tag="IXT22_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4863872.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3536 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaatt
//
LOCUS       DACGLI010000078        10760 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.082, whole genome shotgun sequence.
ACCESSION   DACGLI010000078 DACGLI010000000
VERSION     DACGLI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.082"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(59..1042)
                     /locus_tag="IXT22_002550"
                     /pseudo
     CDS             complement(59..1042)
                     /locus_tag="IXT22_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="IXT22_002551"
     CDS             complement(1437..2279)
                     /locus_tag="IXT22_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4863873.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="IXT22_002552"
     CDS             2604..3020
                     /locus_tag="IXT22_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4863874.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="IXT22_002553"
     CDS             3017..3487
                     /locus_tag="IXT22_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863875.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="IXT22_002554"
     CDS             3501..4274
                     /locus_tag="IXT22_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863876.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="IXT22_002555"
     CDS             4288..5100
                     /locus_tag="IXT22_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4863877.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="IXT22_002556"
     CDS             5154..6119
                     /locus_tag="IXT22_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4863878.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6256..8979
                     /locus_tag="IXT22_002557"
     CDS             6256..8979
                     /locus_tag="IXT22_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4863879.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8992..9624
                     /locus_tag="IXT22_002558"
     CDS             8992..9624
                     /locus_tag="IXT22_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4863880.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9829..10056
                     /locus_tag="IXT22_002559"
     CDS             9829..10056
                     /locus_tag="IXT22_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAQ4863881.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10125..10391
                     /locus_tag="IXT22_002560"
     CDS             10125..10391
                     /locus_tag="IXT22_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4863882.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10381..10650
                     /locus_tag="IXT22_002561"
     CDS             10381..10650
                     /locus_tag="IXT22_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4863883.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3566 a         1716 c         2102 g         3376 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcaagatgca gcgattaaat gactatcttt atcaactaac attgcttttg
     6301 aaatctacgc cttcagataa ttattcagct cgcagtattt cgcaagctct acagttgaat
     6361 agaagtacaa tcagtagcta cttaaatgaa ggtgttcgtg aagggctttt cataaaagta
     6421 aaaagttacc cggttttatt tttacataga acagctcttg aagaactaca tatcacactg
     6481 aataactccg aaatagaatc aattgaaagc ttgttaacaa tttctcaaaa acccgcatta
     6541 gatcaagtaa ttggctctaa aggaagtttg aaagaagcaa ttgatcaaat taaaacggca
     6601 gtcttatatc ctggaaaagg gttgccttta ttattgatcg gcgctagtgg atcagggaaa
     6661 acctttctag cgaataaaat atatgaatat gcagtagaag aaaaggtcat tcacacatcg
     6721 gcacctttca tagattataa ttgtgcacaa tatgtgagca atccagagtt actatcctct
     6781 gctttatttg gctacacgaa aggagcattt accggagcaa gccaggagca tactggtttg
     6841 ctagaaaaag ccgatggagg agtattgttt ttagatgaag tgcatcgctt atctgaagaa
     6901 gggcaagaga aattatttac atttatggat acgggtgaat tctctcctat gggggataat
     6961 agtattcgga aaaaagccga tgttcgatta gtctttgcaa caacagaaaa tatatatacg
     7021 actttcttac caacttttct taggagattg ccagttattg ttaatctacc tagatttcaa
     7081 caacgtccgt cgtttgaacg tctgtcattg attgatgaat tttttgtttc tgagagccaa
     7141 attttagcta aggaactatc tgtttctgat gcattgattc atttcttaat gaatagtgat
     7201 tttgaaggta acgtggggaa tattaaaaat attatcaagt atgcttgcgg aaacgcatat
     7261 atccaccaga agagtcagca aacaattcaa gttaaattat tggatatgcc tttagagtac
     7321 agttataaat tcaaggagca actaaataaa cccagaaaga aaagagcaga tcgaatctac
     7381 tatccagaag aaacacgaca agtgcaacta gaaagaaaca atcagctttt tgttcaattt
     7441 tttgaccaat tacttactgg attctctgaa gtgattgaaa ataacaagga tattaaacta
     7501 tttttagaag aaatggttac caaggtaaca caagtaatgg atacgcttat ttttcaagag
     7561 gattacgaaa aagagcagtc tttatacgcc attctaaact atcatattcg tcaaagtatt
     7621 gattttatgc gagaaagcta cgggtttgaa caagatggta accgggtagt cgctttggcc
     7681 aactatctat atgtcaagga taatcaagtg atttttgaaa atagtcttca agaaaagaaa
     7741 accaaagatc agcttaacga attttttgct aatgttcttg aaacccctta ttggtatgca
     7801 aaaaaaatct taagcctttt atctgagtgt ttagatcaac ctgtgtatga agaggacatt
     7861 ttctttatta cgctatattt ttatagtttg aatgtcacga atgttaaaac aggtattaag
     7921 agtattgtgc tagctcatgg ttattctaca gctagtagta tggcgaatgt tgccaaccgt
     7981 atgctgaata agaacgtttt tcaagcttat gatatgcctt tagatattac attagagaaa
     8041 attgaagcaa aattgattca attccttgga gattatcgaa cagattcagg cttgatttta
     8101 ttggtagata tgggttcact aaaccaacta ggcggtttat tagtgaatca tctaaatgga
     8161 ccactgttaa tcattgatca tatcaataca ccgttattat tggaagtcgg ccaacaagta
     8221 ttaaacaata aaagtatcac cgaaatagga gcagaaattg aaacaagtct tactttcaaa
     8281 aagcagttac tacttcccaa gaaaaagaaa aagaaagcca tcattacttg ttgttataca
     8341 gggattggta gtgcgaccca gattcaggag attttaacga aatgcttgaa agatgcagtt
     8401 agagaattag taattattcc gtatgattac aaaaagctgt tagaaaacaa gaattttgag
     8461 actccttttc aattatacga tgtcatcatg attgtaggta cagaagatcc caaaattaat
     8521 cagattccat atattggatt agatcgcctg attaatgggg gaagcattgg cgaatttgtt
     8581 cattacttgg aaaaagagct gactattgaa gtgaacgatt tacaaaaaga attaattttc
     8641 aatttttcaa ttagtaaaat tgtcgaaaat ttaaccattt tggatccaga taaggtgcta
     8701 tcttttgtac aaaaagcaat taaagaatta tcgaagttat taaattttga tttttctaat
     8761 aatcagctgt ttttgttgta ccttcactgt agttgtatga ttgaacgaat tgtacgtaaa
     8821 gaaagtgtgg atgagcaaga ggacattgaa gaatatatgc aagcaaatgg agaaataatg
     8881 gataaaattc atagcgcttt ttttgagatt gaaagggaat acacaattga aataccagat
     8941 ttagagttgc gattattgag cgatattgtt caaggatagg agtgaattcg aatgacaatg
     9001 ggagtaattt ttgatatgga tggggtactc atagatagcg agacatttta ttttgagaga
     9061 agaatgaact tctttcaaga actggagata gatccaggat caaaccagat tgatgattat
     9121 gtggggaaaa cagaagctgc aatatgggaa acattagttc ctgaggacaa atcattaaga
     9181 gaggaacttt atccgaaata tgtagattat cgaaaaacgc atccaattga tttcgctaaa
     9241 gctttacgaa aagaagtgaa accgttactt gacttcctca agaagcggga tataccattg
     9301 gcactggcat cttcttctcc agctgtcgag atagagagta tgctcattca atgtgaactt
     9361 actgaatatt tttcctttgt tataagtggt gagtcattaa aacaaagcaa accacatccc
     9421 gaaatatatt taaaagcgaa acagcaatta gactgtgact tctttattgc agtagaggat
     9481 tcaacgattg gtattaaatc agcaaaggca gcaaatatct atacggcggc actaaaacaa
     9541 ccaatgcaaa tcgatcagag tgaagcagac atacaaattg aaagtctaca agaactggaa
     9601 caaattgttt tagaaaaagg ttagtgaatt aatggaaata aggctatata tctgtgctag
     9661 ctattttgac taaccaaaaa aacttgctat aattcaggtg tagtaaaagg tgctggtaac
     9721 accttttacg aaaatgcttc ggcagtgata atgggattgg ctttttaagt tttttatttt
     9781 gttcgcaatc cctaaggtca tgtgaatgat cctagggatt gctagaatat tttgcaacag
     9841 aaccaaaata cgaatagtta tcaagcagcc atattgactg cggtcaattt aggaggggat
     9901 actgatacta ctgctgccgt aactggtgct cttgcgggta ttctttacgg gggtgaagtg
     9961 atccctgaaa attggagaaa atcgcttcaa aatgaccagc ttcttaaaac gatcagtcag
    10021 agattttgcg ataccgtgct atctcaaaga atttgaataa tggatatgat gcaaatcttg
    10081 tttgtactaa cgttgtattg acaaaaagga ttttatttag tacaatgtta gtacaaatga
    10141 tgaacggagg tagaatcatg tctcaatcaa ccattacatt taggattccc gacgatgaaa
    10201 aagaactggt attagaatat gcaaaagcac acaattcttc attgaccgaa ctttatcgaa
    10261 atgctgtact ggataaaatc gaagatgaaa tcgatctacg gactttacgg agtgcaattg
    10321 aagtttccaa agagaaaaaa gagagtggta tttctcaaga ggaaatggag aaactgctaa
    10381 atgaattata aagtcatcta catgccgcaa gcccagaagc aattaaaaaa aatggacaga
    10441 aaccaagcta aaataattgt cgcctggatc agaaagaatt tagaaaacac gactgacccg
    10501 cgtcagcacg gaaaaggttt gactggaaat aagagtgggg aatggcgcta tcgaattgga
    10561 aactatcgaa tattggctaa tatttgtgat tctgaaattg aaatccagat attctcaatt
    10621 ggacatagaa gtacaatata taaaagataa ccgtttttgg aacgaagtag agtttcgaaa
    10681 gtcaatgtat aatcttttga attttgcata ataccacagg tagaaactac ccgatactat
    10741 cggttggttt ctgctttttt
//
LOCUS       DACGLI010000079        10705 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.083, whole genome shotgun sequence.
ACCESSION   DACGLI010000079 DACGLI010000000
VERSION     DACGLI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.083"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(47..697)
                     /locus_tag="IXT22_002562"
     CDS             complement(47..697)
                     /locus_tag="IXT22_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863884.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNINHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(797..1306)
                     /locus_tag="IXT22_002563"
     CDS             complement(797..1306)
                     /locus_tag="IXT22_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAQ4863885.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(1507..2376)
                     /locus_tag="IXT22_002564"
     CDS             complement(1507..2376)
                     /locus_tag="IXT22_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4863886.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(2396..3517)
                     /locus_tag="IXT22_002565"
     CDS             complement(2396..3517)
                     /locus_tag="IXT22_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAQ4863887.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(3519..3914)
                     /locus_tag="IXT22_002566"
     CDS             complement(3519..3914)
                     /locus_tag="IXT22_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4863888.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(3933..4730)
                     /locus_tag="IXT22_002567"
     CDS             complement(3933..4730)
                     /locus_tag="IXT22_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4863889.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(4732..5520)
                     /locus_tag="IXT22_002568"
     CDS             complement(4732..5520)
                     /locus_tag="IXT22_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4863890.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(5534..6010)
                     /locus_tag="IXT22_002569"
     CDS             complement(5534..6010)
                     /locus_tag="IXT22_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4863891.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(6082..8739)
                     /locus_tag="IXT22_002570"
     CDS             complement(6082..8739)
                     /locus_tag="IXT22_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4863892.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(8758..9162)
                     /locus_tag="IXT22_002571"
     CDS             complement(8758..9162)
                     /locus_tag="IXT22_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAQ4863893.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(9394..9651)
                     /locus_tag="IXT22_002572"
     CDS             complement(9394..9651)
                     /locus_tag="IXT22_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAQ4863894.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(9776..10108)
                     /locus_tag="IXT22_002573"
     CDS             complement(9776..10108)
                     /locus_tag="IXT22_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863895.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         3332 a         2164 c         1486 g         3723 t
ORIGIN      
        1 ttccattttt acagttataa ctagtattat catgaaaaat agccttttat tgtctatggg
       61 aataataatt taaaattggt acttttttat taattagttc atcgcccaat aatctctcca
      121 gtttcttagc atctcctgac tcaaccggaa ttatccaagc ccagtctaaa taatttttta
      181 aaatctcatc atattttgca aatatttcat tgccatattc cgtccttaaa attatatttt
      241 cagtgccaga caagtgattt atattgagtt gataaaaaag atctccatct aaaaaaatat
      301 cattagaaga agatttcccc acagtaatga ccattccatc agctctatgt gttacataca
      361 aataattgta tgacctcatt tcacctaatg aatcaattat ttcttgccct ttagctctaa
      421 tatattgatc tctattacct atctcactct tatttaacaa aagttttttc atgtcaaatt
      481 taatcggctg ttttattttt gtaaattcgc ttctactact aatccaatcc gagattaatt
      541 tttcaacatg tcccagagta aactctgatt tattcgctaa atactttttt tgttgtatta
      601 aagacatctt tccccgaagc tcaaaattga gcctacatcg attctctatc tcttcaaaaa
      661 gcatcttatc ttcatcattc ttatattcat cattcataaa accaatccag ctcctcgatt
      721 aagataatat tttaatctca tacaaaaact agctctcatc aaaacaacca ttgttttgat
      781 ttctcatgaa atttctttat acttttctcc gattataaat tcctaacccc ttgagaaaat
      841 tacgcatata tttatctccg caaggcttaa aatttcgttg gccttctttt ctcaaaaatg
      901 ccccgatttc gccttttgat ggatagattt ctgcctcagc aaaaacgtct aaaatatcat
      961 cagtggtcat agacaaggcg atttttaatt tttttagcaa cacattgttg atatatttga
     1021 tttccttgct tttttgcggc gtgtctacta tcggcttatc tttttgcgga ccacgcgcca
     1081 agagaatcag gccatttagg aatgcgtcaa aaacttggtt gttgatggtt ttttcataca
     1141 cattattttc tgcattatct ttgttcttat cctgtacttt ggtcagtacc gcctgagctt
     1201 cttctttagt cagtggtaca ccgcctagct caaaagcttt aatcaaatcc gtatctttca
     1261 aatcaatcgc ataacgcaat cgcaataacc tatcattgtt attcatttgt tcctccgaag
     1321 tatttagtct ttactttctt acgtactttt tgtcttgcta agatttttag gatcaatgat
     1381 aaaaaccgca tcacttatga taaggcgctg ggtatcatga gtgaatgata ttgctgaata
     1441 caaatagtcc gaccacatta agttgatcgg acttcataag cattttattg actaatactt
     1501 ttttgcttaa gaattgattc taacatcttt tgctaaagtt aagcatccta tagttcctgc
     1561 attatctgct aacttaggtg tgacaatgta ttcttcgata tttggcgtat cgacatagcc
     1621 gttaattagt tctaaaaaac gtctttgtac tttctttttc agatgttctt gttgcatgac
     1681 accaccacca aaaattataa tatctggtga aagcatcagg gtcgtattac aggcacattg
     1741 tgcaatataa tccgcctcga tttcccagaa cggatcttct atagaaagat cttgtccctt
     1801 ggttcccgta cgcatctcga tagcgggtcc agatgccaac ccttcgagac aatcatgatg
     1861 aaaaggacaa gtaccagaga aagtatctcc tgaatgtctc ttaactaacg tatgccccat
     1921 ttctggatgg ctaaaccctt caacaaaaat cccatcttgt atagctcctc caccaattcc
     1981 agttccaaca gtgtaataaa caacactgga taaacctttt ccatgacctg aaacatactc
     2041 cccgtaacaa gcagcattca catcggttgt ccaggcaatt ggaatttcga aatgcttatt
     2101 caacgttcca acaaaatcaa aatttttcca ggcagttttt ggagtagagg tgatatgtcc
     2161 ataggtcttt gattcacgat ggatatcaat cggtccaaat gaccctactc caatgctttc
     2221 taattgttct ttatagtgat taaagaaatc aattaccaaa ctcattgttt cattcggtgt
     2281 agttgtagga aaactcactc tttctaaaac ctttaaatca tcattgccaa tggcacaaac
     2341 aaatttagtc ccacctgctt ctattgagcc atacatttct tactccaccg tccttttatc
     2401 taggaattcg ttcttccctg tctaatagtt tttcgaaaaa ctcatgtggt tccttttggt
     2461 accaataggc aacagaagaa atatcgtctt gacgctcata aagcttgatg tcatcatttc
     2521 ctagggtttg gaaagtaaca cgtaaatttt ctttgaaact aatggggtcg ggtaaatgcc
     2581 agcggtacaa cccatgcatc ggtaaagcat catcgccaaa accatgaact ggatttggat
     2641 taggttttcc agcactaaaa taatcccggg tgtgatctct tttagattga aaaggatagc
     2701 ccataaatag cgtattaaaa ttttgagcat atgccctttc tccaaagttc tttttatgga
     2761 aagcccaagc gccgccaaaa taatcttctg ctcctgtaga tgttattgta gggaaatctt
     2821 catctccatc tatataaaac ttaaattctc cttcccccca ccagtatctt tccaatgcgc
     2881 acaaagcaaa gtaggttcct acataatacc cagtgccttt gattccatca ataagggtgt
     2941 aatcttttcc ttttgtcgtg atgggttcac ggttccattt agcatgaaaa tacatcgcat
     3001 catccggtac ttcagtcaat gcataattaa atgtataaaa aatgtgctta ataaactcag
     3061 gatgttcatt cgttaaagta atcttagctt tttttcgaaa tggcatctca aaatagcaat
     3121 tcatccctga tgttggattc actacgattg gtaaggaatt cacttcgcat cttgtcccaa
     3181 acccattaca aaaaaaatct cctaatggac tttctacaga aggagtggat tcatcatccc
     3241 aataaatacg caaaattaaa tcacgtaaga cgaaactccc agcgattgtt ttgtctgtca
     3301 ctgtcatcca aaaatgacgt aaaattccag ggccttccat ttctgctaaa gtaattgtct
     3361 ctccagcatt tatcggaaca gaaggtgacc cttttctccc aattcctaga tgactcgctg
     3421 tcattgccgc tttccctttt tcaccatttt tattttctgg tgaaatagtt ctactttcct
     3481 ctcccttgtg gagccatata ttatttaaac aattcatttt attcgtcctc tatcctttct
     3541 tcactttttt gattattcat atagatgatt tgttgttgtg cctccgcaat aattgctcca
     3601 atatctaaat tatcatttcc taactgcaaa gcgattgaca ttgccaaggg aagattcatt
     3661 cctgcaatta cgtgcactct gtcagaaata taggtaaaaa acttttgatt tacacttcct
     3721 ccagccatgt cagttaaaac aattatttcg tctgtagtat ccactaactc tttaatttgt
     3781 tcatctatat catcaatttc ttcgacatat gcacataagc tactaatttg attatgcata
     3841 cctgttaaaa actctagtgt ctctttaaaa ccctcagcta gtattgaatg gctagcaatg
     3901 atcaatcttc tcataattca aatccttttc ctttacgcta atattccaaa tgcagccata
     3961 accatcgcaa aaacaataac gagtagaatc aaaatggtca tactgatttt tttcttactg
     4021 agtagataat atgctgcagc agtaataatt actggaatta atgttggtaa aattttgtcc
     4081 aacattggtt ggattttcat actaacttca ccaaaagtga atttaagtgg cgttgaaaca
     4141 ctgataactg aagcaattaa tgatccaact actgttagcc ccaatactga agcagcttca
     4201 gttaaataat taatcttttc accgtattca gtaacaatct tcattccctg cttataacca
     4261 aattcaaagc ctctcattcg gaaaaagaag attaccatga ttaaaatgaa ccataaaaag
     4321 attcctacag gattattttc taaagccata taagccgcaa ttgatcccat gatggttggg
     4381 atcatcgtca tcaaaagaga gtccccaata ccagcaattg gacccatcgt accaacttta
     4441 aagtcattaa tcgcatcttt tgcttctaat ccttgctttt cctccattgc aacacaagca
     4501 cctaaaataa tggctgccag ccaaggctgt gtattgtaat actgaaagtg attatttaaa
     4561 gcttcgatgt attcatcatc atctttgtat aattttctta aaataggtga caatgcgtaa
     4621 gtcacagatg caccttgctg tgtttgataa ttaaaggtac aaactgacat caaccaacga
     4681 tagttcgctt tcctaagatc ctttttcgtt acttgatatt tttcgctcat tttattcatc
     4741 ctccccaata aacccaacat cagaagctcc cgcagaagca gtgatttgtg catctttttc
     4801 agctctatga tacacattaa atgctaaagc gaatcctatg atcgccgctc caataatagg
     4861 taccttcaaa aaagcggcta agaaaaatcc aacaagtaaa taactaatgt atcgacctgt
     4921 aggcataaag cgtaacaaca tcgcaatacc aacagcaggc aacatttttc cggctaatgt
     4981 tagcccatcc ataaaccaat taggtaaaac atccaaaacg taattaacag cagactgtcc
     5041 taaagtaacg gcaataaata ctggaattgc tgcagataaa ccaaagaaaa ttggccccaa
     5101 ccacaaaaca ctattcattt tcttaaattc tcgtttattc gcatattcct gtgatttgcg
     5161 aacaacaaaa ccatttaaga ttttgacaat tacatctagt tgcaccccta acatacctac
     5221 aggtagtcct attgctaatc cggcttctac tccaagctgg ctaccaaatg ccgttgcaat
     5281 aattgcgcac gttccatagt ccggtacaga tgagccacca aaaccggcaa ctcctaatga
     5341 catcaattga actgtaccgc caactatcaa acctgttttt atatcaccca tcaaaattcc
     5401 tgtgaataat ccccaaaaaa ctgcgtaatt tacaaagatc atcggaatcc cataataatc
     5461 aacatgttta ataaatgcta atatagtcag cataataatt tgaaaaatag taaaatgcat
     5521 tatccttact cctttatcct aattttgatt gaatttcctg tgccttatcc gccggaacaa
     5581 attgtgtaac aatttctaca ccagaatcca acaatttttt atacgtgctg atattttcat
     5641 ctgatgcata ggctctagaa gatagctgta atgcattatc tttaacaaca gtaccgccaa
     5701 caattagtcg gtcaattcta ataccgttat ctactaaatg aaggattgtt tccggctctt
     5761 tcacgatgac aaatactttt tcctgatcgt atttcccctt tttaaaattc gcaatcgctg
     5821 tttcttcagt gataattgat acagccattc cagcaggtct agctaaacgc atacttgatt
     5881 tttggatgtc gttatttgcg acagaatcat cgatcaccat cactctgttt gctttagaca
     5941 ttggtgccca ttgcgtgaca ataatcccat gcaataaacg gttatcaact ctcgacataa
     6001 caatactcat aaatacttcc tcctttatct ttcattttct tacaagcaat taccatgcca
     6061 aaacaaaaag aacttgataa atcaagctct ttttacataa tcataaacgt atttaacctc
     6121 atgaatcggg atgtcgacac tataataatg ttcaacgaca ctgaaagatt gcttaaaatg
     6181 tgtctgaaat ttttgaaatt cctcactcgt ttcattgaaa taaatttcat cttccaaagt
     6241 attttgtttt actaatcgtt caattaagca actaatgtga acatataatc cgaaacacgt
     6301 attattatca aatgaaattc ctagatcatt ttgtaagatg tatatagcat ctgaaacccg
     6361 ttctaataat ttagtcggat ttaatatggt caattgctcc attaaattcg ttagactaaa
     6421 attcttcaga atattattgt tcaaaacttt cagttcatta tcattaaagt gtctattcaa
     6481 ttgattggag aatttactta tattcattcc taaaatcata tcttcaattg aaaagaattc
     6541 tacatcttct agatgtggat ttagtgttcc aacaataaaa agaatattgt tctctttacg
     6601 aagctccgat aaatagtttt cattcactaa agagtaatag tcacacgttt ctatgacaag
     6661 atcagtatcc cttggaaagc tatcttcaag tatctttttt aatttaaacg aagttcctaa
     6721 tccgcttgca caagaacaga caatcatatc cttcttaata tttgatgatt cataaatata
     6781 atccacattt tgattttctt ttacttgttc aagaatctgt ttaagcggta aatctaataa
     6841 tatctgattt gcaacatcaa tagccattct tgttgaaaca ttgtttagta gtccgaattt
     6901 tttttgagcg tctagttcca aatttagata aattttctcc agtgaaccca tatcaacaag
     6961 taaaataatt tcttcatatc cggtacactc ttgtaagtat ctattaattt tgtctgcaat
     7021 ctcactactt gaagtcatta gtggcatatc aatggcgtcg tatatatatc tctcaacgat
     7081 cctattagca gtacttgcta tacaggttgc cgttagatct ccatgagcca aaatcagtgc
     7141 taaacgtttt tgctgaaatt ctttactaca cattaactta aataaaataa ccaaaacatt
     7201 tttttgaatt tttgttaaat aaatatcccc tatttgaata aaacgattga ctaattgaac
     7261 ttctcgacta caccaactat taatatcatt gatgaaggaa tataatttat cgtccgatgt
     7321 taattggatt tgataaatcc aagaattcaa aaagatagac gttatttgaa gataataata
     7381 gtcaaattct atttgaaaat ctctctctat ttccttaaca tactgtctaa atcgaatctc
     7441 ttgataggtg ggatatgtta aagctgaatt attttggata tcaacattct tttgtctaaa
     7501 atatctatca tatttctcaa aaagctgctg cttatcagtg tctttcttcc acgtttgata
     7561 aagatactct ataagttcgt tgatattaaa aacttcgtct actttttcca aatcatccat
     7621 ttgaatatat tttaattcat tctgtctttt cataaccttc atgccgttga aattcaccca
     7681 ttgtggtaaa tgatacatct gaatataaag ttcttccaaa tcatctaaga aataaaaggc
     7741 attggcacag gtcaattgaa tgatattttt caaattgcca acattttcac taaagcgata
     7801 gtttaataaa aaatctaata attgttgaga tatcagtatt ttctttgcta gtctttcttc
     7861 ttctgattta aaaaatatct tgattaactg ttttctttca taaagagaac gactgtctaa
     7921 tgttggaagt gttagcttta caggtattct tctcaacaaa gttgataata gtttatcctc
     7981 aggtggttct gatgttgcaa atataatcca gcaacttgat gtgtaccagt tttcattatc
     8041 acccatccga tgaaatttcc tcgtatccat aaactgaaaa agtttctcct gacattcatt
     8101 gctcaatgca tgaatttcat ctaaaaataa gactccatta ttagctaatt ctgctaaacc
     8161 ctttcttcca tcttcggctc ctgtatatgc accttttaca tgcccaaaaa aattggacaa
     8221 gaaaagttct ggattattgg catattcact acaattaact gaaatgaaag atgccttctc
     8281 ttctatataa ttattggcca acaaatcctt atacacataa tttgctaaat agctttttcc
     8341 agttccagtc tcgccatgaa gtaaaatggg taagccattt ggcggatagt agattgctgc
     8401 tttaatttga gcaattacat ttcgcagact tccttgactt ccgataaccc tttctattcc
     8461 aaccctaaaa gagctatcat accatttttc cgcttcctct gaagagctaa aaatttgttg
     8521 atttggaact ttctccggta aagaaaagaa gattactgga cgagtattga tttttccaaa
     8581 ttctccatct tttacgaatt cattcaaata ttgagagaca atattacgac taacatttaa
     8641 tttttcagat attttctgtg ctgtattgtt cccccattta tttttaatct cagagttctc
     8701 tatgacataa ttgacaatgc gttcttttaa ttcttccatc acagcacctc ctcgacacta
     8761 ttcgaatttt gccgacagta tttttccata aatatgactt gctaaaaagg ctttgtttag
     8821 atcattcaat tggaacgttg cttgttttgc ttgatccgct aagacgttga aaagatactc
     8881 tggcgaaatc gcatacccca aaatatcaac gattgttgca atcagatctt cttttgattc
     8941 ttcatctgaa agtaattcac gatacaacat cgtttgtttg cttactgtgt catattcctc
     9001 taaggattca tctgctaaaa gaaccacttg ttccaacaaa cggtcggata aatatttata
     9061 gaaaatcagc cccaataaat aatttttata ttctgacgca tccattttac tacggagatt
     9121 atctgccgca ctaaataact tctgatttaa ttctgcaccc aaaaagatac actcctatct
     9181 cttatttaaa gttgctatat accctcttat tttagcatac tcagttttag aaaaagcaaa
     9241 aaaataaaga aacttattct tgataacaag ctacgtgacg tatatcccta acacaaaaat
     9301 agccatatcc tttggtttgg atacggctat ttgatattac tcattcaatt atcaaatcac
     9361 agtaggtgtg aatctcatcg ggatcggcaa tatctacttc tgattaggat caaaggtgat
     9421 tttctcaata aaggtgtgat acaaagcttt aacttgcttc ttctcactct ggataagaaa
     9481 gcaatccaaa ctagtcaata tctgttggac atctttgact tgaatcggtt ccccttgttg
     9541 ttgaaagatc cctaagattt cattctctcg aatttgtaac tgtcttcgtt tttcagtcaa
     9601 ttcatttaaa cgatctttta acatcggaaa caattcggga ctatcttcca aagcagcttc
     9661 ctgtttttgc tctaatagtt agattttgcg taccattttc ttcttttatt ttccttcgat
     9721 tgctgatttt aatatagtct aaaggaaatt tatatttatt gtattcttta taacttcaag
     9781 agaacttcgt ttgagtatta ctgtattttt ttaattccat aagaaaatta gttattacct
     9841 gccacctaat cagcaaatct gaacctgagt caatataatt aatattattt tccatctcca
     9901 acattgtaag tactgttggt gttaatatag ggactttgta caattgtatt tttttgattt
     9961 tatcatctgc acaaaggaga ttttttaaat ctaatccttc ttttatttca aaagttgaat
    10021 tttttaaatc tataagagta aaaccaattc cttcatactg aatttctgaa aatcgaattt
    10081 ttctcccagt tgatagatca aggggcagaa aaccttttat tacattgtga gtgtcaccat
    10141 catttacaat gtcattagga attttgattt tagaattctg tggagcacct attggaagat
    10201 aataattcat tataattttg tagtcttcat gaggaaataa agtactttta ggattgctaa
    10261 gatattctcg taccgaatct aagaatggct tatccattga atcttcatcc ccatttaaac
    10321 taaaaaacat tcctacaatt gcttttgcaa ctctaagtga attcattttc tttattgaat
    10381 gtgttaaatc agacttacca ttctttaaac ttgtattgtt ataaaggaaa tttttattgt
    10441 cttctgcaaa tctaatatat tcctcaacat actcactacc aaaaaaacta ttacatttac
    10501 tacataacgt attggaatgg caacagtttt tttgacaaat tttataaggt gcagaacttc
    10561 tttccgtatg ctattccgat tgtccttgac aatgagcctc ctcggatgtg acgatcttcg
    10621 gcaggagcta acagttaaag ttagactgcc tcgctagcgt tagcacatcc gagctcatta
    10681 tcaaggattc gctgcgccaa tttct
//
LOCUS       DACGLI010000080        10220 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.084, whole genome shotgun sequence.
ACCESSION   DACGLI010000080 DACGLI010000000
VERSION     DACGLI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.084"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            436..1395
                     /locus_tag="IXT22_002574"
     CDS             436..1395
                     /locus_tag="IXT22_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4863896.1"
                     /translation="MTYTHLTTDELVIIESYFKINQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            1872..2072
                     /locus_tag="IXT22_002575"
                     /pseudo
     CDS             1872..2072
                     /locus_tag="IXT22_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2784..3389)
                     /locus_tag="IXT22_002576"
     CDS             complement(2784..3389)
                     /locus_tag="IXT22_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4863897.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            3571..3906
                     /locus_tag="IXT22_002577"
                     /pseudo
     CDS             3571..3906
                     /locus_tag="IXT22_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4071..4298
                     /locus_tag="IXT22_002578"
                     /pseudo
     CDS             4071..4298
                     /locus_tag="IXT22_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            4424..5395
                     /locus_tag="IXT22_002579"
     CDS             4424..5395
                     /locus_tag="IXT22_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4863898.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            5535..6848
                     /locus_tag="IXT22_002580"
     CDS             5535..6848
                     /locus_tag="IXT22_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4863899.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            6891..7757
                     /locus_tag="IXT22_002581"
     CDS             6891..7757
                     /locus_tag="IXT22_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4863900.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            7754..8602
                     /locus_tag="IXT22_002582"
     CDS             7754..8602
                     /locus_tag="IXT22_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4863901.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            8616..10088
                     /locus_tag="IXT22_002583"
     CDS             8616..10088
                     /locus_tag="IXT22_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAQ4863902.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            10105..>10220
                     /locus_tag="IXT22_002584"
     CDS             10105..>10220
                     /locus_tag="IXT22_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4863903.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEET"
BASE COUNT         3290 a         1710 c         2064 g         3156 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc atcgccgatt gtaaaattaa
      361 gctagacaac taaaaaagtc atttgtgcta cactcaaaat agttccgacc aaagaattat
      421 aaggagtgag tacaaatgac ctatacccat cttacaacgg atgaacttgt aataatagag
      481 tcttatttca aaattaatca atctgttgct aaaactgccc attgcttgaa tcgttcaaga
      541 caaacgatcc ataaagtata tctgttcttc aagcaaggaa aatcagcctt agaatattat
      601 caacagtata agaaaaacaa atcaaactgt ggtagacgtc cgcttgtttt acccgaggaa
      661 caatcagaat atattcaaag aaaggttgtt caaggatgga cacccgatgt gattgttggt
      721 cgtgcagcgt ttcctattag ttgttctgct cgtaccattt atcgtatgtt caaaaagggg
      781 ctatttgatt cttctgactt accgatgaaa ggcaagcgta aaccgaatgg acatcaagaa
      841 agacgtggaa aacaaacttt ccgccgctct attcatgaac gtgaaaagga ttatagccaa
      901 ttctcaaatg agtttggtca ccttgaaggt gacactatcg taggtctgaa acataaaagt
      961 gctgtaatta ccttagttga acgattatca aaagttatca tcacattgaa accgtgtggt
     1021 agacaagcga ttgatattga aaaaaaatta aatcaatggt ttgaatctgt accgaaaaac
     1081 ctattcaaat ccatcacttt tgattgtgga aaggaatttt caaattggaa acagatcagt
     1141 aatgtcaatg atattgccat ttatttcgct gatccaggaa cgccgtctca aagaggccta
     1201 aacgagaatt ctaacggatt gttacgtaga gatggtttat tgaaatctat ggatttcaat
     1261 tcagtagatg aattttttat tcaatctgtc gcatctaaac gaaataatat tcctagaaaa
     1321 tcactggatt atcgaacacc tttggaagta tttttgagtt acgtaagtat tgatgatctg
     1381 tctaacttaa tttgacaatt aagacattta aaaagaaaag tgacagatag gaataaaaac
     1441 ttattaaatg tagttatgat ctgttatatt tcatttctaa tactaggtct tccacaagca
     1501 gtgtttcctg aaatgttttc tggagactgg ggtattgtca gctattctat attaacattg
     1561 attgctatgg ttttaggtac ttcattttat aatgcttttg taagtaagca tgttgaggaa
     1621 tatgaagtat taatgtactt aaaagagaaa aaaacaagta attaatatga gaacaccacg
     1681 catagttttt attttgagat attctagaat gaaacacatt aagaacgaaa gcaaagcaaa
     1741 agacgccaga acttctacta ccttctaagt tttttcatat ttgtttgtta tgctatacat
     1801 agatctgcat aattagactt gcgctgcccg ttattgaagt ttcaggcagc gctctttttg
     1861 ggggatcgat aatggaagaa gaaaaaatat ttgagaaacg ctggcagcta gcatcaagtg
     1921 aacaaagagc aagatacaat aatttgatca cctcctaccc cactgttgac tagacatata
     1981 aggaaaagaa atacttactt tggctgtgcc agttagatat agataccttt gaaacatttg
     2041 aagtgatcct agataaaatt aaacagaatt gatcagaaac aagcgaagcc ttctctcggt
     2101 tcgcttgttt tgctatttat tagttggctc agggcaactc taagctcgtt tgaaagaaaa
     2161 ccgatggata atccccttgt ttgtaccact ttagaataca tggatgtacg tattgccatt
     2221 gactcctatt agttactgaa aaaaaattta aacaagttga gtattgcaga taaatagctc
     2281 cagtgaggtg aataactgct ccactcaagg caatagatag ctccatccag ggcaacaaac
     2341 tgctccactt tcatatttaa tagatgaata accttctgta taatagaaag gcataccttt
     2401 cggtatgaca acttatacag aatgttattt tattggttca ctatcgaaaa attttggagc
     2461 tttatttttc cggtatttct caacgaacga ttagtttaac tgtgggaagc tccagacata
     2521 cgattcgaga agttacttct cgagcagaca ggaagggggt gactgaacta accgctgata
     2581 tgagcgatac ttggctgtag gaatatcttt ttccggaaaa acaaacaaca gcacgaggtt
     2641 accttcctgt agactgggaa tatgttcata aagaactaat gaaaaagaat atgacattga
     2701 aactccttca tagagaatat ggggtacatg gaacatagaa acgaaaatgc acggtagaaa
     2761 agcgaatgaa tatagtataa attctacaaa tcattcgctt tctttatttt atatatggtt
     2821 ggtcgagaga gaccattttc tttggcaatt tctgcaactg gaactccttg atttaacatg
     2881 tccaccacag ttttaaagac taatcgtttt tgcggatctg ttgagttctc agaatattca
     2941 attggtcgcc ccttatatcg accagctttt ttggccaata atactccttg ccgctgacgt
     3001 tcacggattt tctcacgttc gttttgtgca atataactta gcaatgataa aaacatatcg
     3061 aacatagcag tatctaggag ttcatttcca gtattaaaat ctaaaaactg tgcatctagt
     3121 atttttaatg ctactttttt ctgtttcata aaggtaactg tattttttat gtcttcataa
     3181 tctctgccta ggcgatccag tgatgcaaca atgacacaat caccttctcg gatataattt
     3241 agtaattttt gaaactcagg tcgctggata tctttaccac tggctttttc ttggaataat
     3301 ttatcaatgt taaggtcttc catcattgcc aattgtcgat ctaaattttg atcttgtgaa
     3361 gacactctaa tatatccaat ttttgccata aaaactcctt ttaaaaaatg atataattta
     3421 catgtaaaat ttacttgtag ttttactgtt atcatagcat ttttaaaaat aaattttaag
     3481 tctacttata atttactttg gaggttttga atgaatgaaa ttaagcgcaa taaaaattct
     3541 tttggtgttt atttaggaga gcctagctcg gaacagttaa ataaaggtga agctcgtcat
     3601 gctctatgtc gaaatatatt ttatggtaga aaaggcaaac tttatcaaac ttattacgac
     3661 ggtatggagg aacagctcaa cgcattagga ttagtaacta atgctatcat atattggaat
     3721 tcactatatt tagaaaaagt ctttgaacaa attaaaacgg aagggttcga ctgttccgaa
     3781 gaagtgttac gcaagcaatt tccattaatt agtgatcaca ttaattttgt tggcaaatat
     3841 agtttccgct atgaaaaaga attatcgaat ggaatactac gtccgttaaa tatagagaat
     3901 tattgagaat gttcgtcttt tggttcctac cgtgcatttt cgcacggatg ttccagatac
     3961 tatttttgaa tgtataaaat tgaaaacaca agaatactaa taaatcaacg attcttgtgt
     4021 ttttaatttt tcactaccgt gcattttcgt ttctatgttc catgtacccc aatcttgaaa
     4081 aattaattaa agacttagat aaagccattg acgacttagt cgtggtgcta ccggagtatc
     4141 aatgtttaac cagtatccca ggtattggtc ctgtttaggc tgctggaata ctcgctgaaa
     4201 ttggtccaat tgaacgtttt tctgatgaaa taaaattgac aaagtatgcc ggcctatatt
     4261 ggcgacagag tcaatccggt aaatctgaat acgaaaattt ttttacgaaa agcttcacgt
     4321 ctaatatcta ttttaaaata aaaatattcc tgctaatttg gaatcgtttc cttcttttgg
     4381 tataataata cctgaaattc ttttgagagg agttgttcgt gaagtgaaaa ctactatgaa
     4441 ggatgttgct gcgttagcag gagttggtgt gggtacggta tctagagtaa taaatggagt
     4501 aaaggtgaaa gaggttacca aagaaaaagt aatggctgca attagtgagc ttaattatga
     4561 gcctgatgaa tatgccagag gtatgaaaac gaatagtagc aatacaatag ctcttatttt
     4621 acctacgatt tggcatccct tcttttccga gtttgcctac tatgtagagg aagctctcag
     4681 ccaaaaaaat tataagcttt ttttgtgtaa tgcgaacggc agtgcggaaa aagaaaaaga
     4741 atatatccaa atggtcaagc agagtaaagt agacggaatt ataggtatta cctattcaga
     4801 cattgataaa tatgtatcat caaatttacc atttgtcagt atagaccgcc atttttcgga
     4861 acaggtttct tatgtaacgg cagataatta tttaggtggg caaattgccg ctcaagaact
     4921 acttactcgt aactgtaaaa acttgtgcta tgttgggggt gtttcacctt accctaacga
     4981 aacaaacaat cgtaaagctg gtttttacaa tatttgtgag gaaaataaaa tagctgtgaa
     5041 ggtattggat atgcctgaac caattagcaa tttagaggaa caattgctcg cttttttttc
     5101 ggataatcct gaaattgata gcatttttac catcaatgat ttcatggctt tggatgtgat
     5161 aaaagcccaa aaaaaactag ggaaggaagc acctaaggat tttcaaatta ttggttttga
     5221 tggagtcaag ctatcgttgc aaaaagacta tttactatca acgattgtac agccgataga
     5281 ggaaatggcc aaggtttcag tagaaacact catggcgatg attttaaatg aagaaccgcc
     5341 taagcgtgtg gtagtaccgg ttttctttca cgctggagag acgactaaag agtaaaaaac
     5401 cggtttataa cgattttttt gagataggtt gacagaaagt gatttcaatg atatcttaaa
     5461 accaattaat tggaaacgtt accaattaat tgaaaaataa aacggaaacg tttcaaaaaa
     5521 taggaggaac atcgatgaaa aagagaatgt tagcaattgc agcaatttta gcattaacag
     5581 ctggaggact tgcaggatgt ggcagtaagg agaaaagttc aggtagcagt gatccaggag
     5641 aaattaagat ttgggttcag ttttctgatg aaacgcctga aggaaaagct tgggcagaga
     5701 ttgtgaacaa ttttaatgat gaatacgagg gtgaatataa agctgttact gagtatattc
     5761 ctcgtagcgg aagcggcggt ggatatgagg ataaagtaaa tgctgcaatt acaaccaata
     5821 cccttcctga tgttattacg ttagatggac cgaatactgc agcttatgct cattcaggag
     5881 tcattgctcc attagatgat tatttgaaag atgcggacat ggatgatgta ttagacagca
     5941 ttattcagca aggaacctac gatggcaaaa tgtatgcgtt tggtttctca gagtccagtg
     6001 tgggtgtcta ttacaataag tcgctgttca aagatgctgg aattacagaa gatcaattgc
     6061 cgacgttaga agatccttgg acttggacgg aatttcaagc aatttgccaa aagctgactg
     6121 ataaatacaa aacgcctgca attgatatgc aaatggcgtc gggagacgaa atgctgacct
     6181 acgcatatac accatttata tggtcgaatg gcggcgatgt cgttaatgct gatggaacca
     6241 aagccgaaga ctattttaac ggtaaaaaat ccgttgaagc gttggaattt attcaagaat
     6301 tggttgaaaa aggttacacc acaatcagtc ctattgaaaa aggatttgaa actggcaaat
     6361 atgccatgat gctgagcggt tcttggacaa tggcagattt agaggaaaac tatcaagaga
     6421 ttgattatgg tattttgcct taccccgttt cagatgcaac tggggagtta gtttcaccaa
     6481 ccggaagctg gcagttagca atgactgaga aaacagagaa aaaggatgct tctgcggcct
     6541 ttattaagtt tgcaaccagt acagaatcta gtcgtattat gagtttaggg aacagtgttc
     6601 tacctatcag aaattcaaca gttgatttaa ttaaagatga agtgtcggaa ggaatgcagg
     6661 tattaattaa gcaaaaccaa ctttctggac atgcccgccc agtggttgta gcttatccgc
     6721 aagtatctag agcattccaa caagcagttc aagatattag ctacttcgag gaaaacccag
     6781 atgtacaaaa agtagcagat agtcgcgctg ctgaaatgca acaggcaatt gatacttcac
     6841 taaaatagaa gtttctaaag ggggccaatc aagtgttaaa aaaaccgaca atgaaagaca
     6901 atttgatagg ttacggcttt ctagcgccag ctttgctgct gctgacgatt tttctgatca
     6961 tacccgtaat catggtaatt tattatgcct ttactgatta ttatttgtta acgccagatg
     7021 ctagacaatt tatcggctta gaaaatttta agcgactgtt cgctgatcca atttttgtaa
     7081 aaagtatttg gaacacggct aaatttgttg tttggattat tccggtccaa ataggggcag
     7141 ctttaggaat ggcacttatt atcaacaaaa atcgtaaagg aaatatcttt tttaaagtag
     7201 ccttttttgc gccagtcgtg atgtccttag tcgttatttc gattttatgg ttgtacttgt
     7261 taaatcctaa tgaaggtctg gttaatacgc tatttgcaaa gattggaatt gcttcgcagc
     7321 cttttttgac tagtcccaaa caagcaatgt atacgcttgt tttcgtatcg gcatggcaag
     7381 gtgcaggata tcagatgctg ctgtttttag ggggaatgca aaatattccg caagacgttt
     7441 atgaggcagc cgaaattgat ggtttttcta agtttcagca atttcgctat atcaccatgc
     7501 cattattaaa gcccacggcg atttttattt tacttaccac attgatttcg gcctttaaac
     7561 taatcattca gccaatggta atgactcaag gtggaccaat gaattctact atgacaatgg
     7621 tttattacat ttaccaaact ggatttacag accgtatggt aggctactcc agctccattg
     7681 cgttaatctt taccactatg attggtttaa ttacaattgc tcaaagaaaa ttggtaaagg
     7741 aggatgatcc agcatgacca agaaatttgg accgctaatg atcgtagaat attgtttgct
     7801 gttcctttta gcggcattat tcattttccc gatgctgtgg atggtagttt cctctatgaa
     7861 gcctgaagca gatgtctatc aaaatttagc ttccttcaaa gcttttttac ctagtttgaa
     7921 tccagctaat tggtttaaaa cttatcaaga ggttatttcc cggttcagtg tgggaactta
     7981 tttattaaac agtatttttt atggtttaac ctttgcctgt gggtcaatca ttgtaaactc
     8041 tttggcgggt tttgcctttg cgaaggttaa tttttcaggc aagaaaatta tctttggagc
     8101 tttgttagct ctgctgattg tcccgatgga gacggtttta attccgcaat ttaccatcgt
     8161 taattcacta ggcttagtga atactcgctt ggcagtgatt ttaccagcga tggccagcgc
     8221 gtttaatatc tatctgttta gaaatttctt tatcgcgatt ccagaagaaa tcattgaatc
     8281 agcgaaatta gatggtgcaa atattgttaa aattttcttt cacatcatgc tgccaatgtc
     8341 taaaccagcc atagccacag taggtgtctt atcctttatc tccagctgga atgattatat
     8401 ttggccgtta atggtcttaa ctgacagcag caaattttca atgcaagtgg caattactac
     8461 gatcaatact acacagccag tttatatcaa tcaagtgatg gctgttttaa ccattgcaac
     8521 gattccactg attattgttt atatcgttgc acaaaaatat attctgcagg gacttggcgg
     8581 ttctggaacg ggtataaaat aggagtgaat agtgaatgtt gcaaaaactt ttaaaggcca
     8641 atgagtttat tgagaaaaat gctcaaacag tcaatcaaga ataccggaat aaatttcatt
     8701 tgatggctcc gattggctgg atgaatgatc caaatggttt tgtttattat caagaggagt
     8761 atcacttgtt ttatcaatat tatccttacg acagcatctg gggaccaatg cattggggcc
     8821 atgctaaaag caaggatcta attcactggg agcatttgcc agtagcactg gcaccaggtg
     8881 aaagctatga caaggaaggc tgtttttccg gcagtgccat agaaaaggat ggcaagctgt
     8941 atttgattta tacaggacac aatgttgtgg aagggcaagt tcgacaagtt cagtgtttgg
     9001 cagtttcaga agatggcatt cactttgaaa aatatgccgg aaatccaatc atcgcagaag
     9061 atcacttagc ttctgttgca acgaccgaag atttccgcga tcccaaagtg tttcagcgaa
     9121 aagaagacta ttttactgta gtcgctacta aaactgcaga tgctcgtgga caaattgtga
     9181 tgttccattc caaagattta ctaacttggg agttttattc cgtattgctg gagggaactc
     9241 cagaacaagg cattgtatgg gaatgcccag acttgtttga actagatggc aaagaagtct
     9301 tgattctttc tcctattcaa atgactccac aaggcaatgc ttaccaaaat acgaactcaa
     9361 ctgttgcttt catcggtact gtcgattggc aaacaggcaa atttctagta gagaattttc
     9421 atgaaatcga tggcggttta gatttttatg caccccagac ctgtgaaaac gaagcaggcc
     9481 aaagaataat gattgcttgg atgcaaatgt ggcagcgtaa aatacctacg aatgatctgg
     9541 gccatggttg gtcaggttcc atgaccttgc ctagagagct gagggtggct gataatcaat
     9601 tgttgcaacg gccagtttca tcaatttatc aagtaattga tccgcaggaa aggattgaat
     9661 gggcgaagac tgaagagaat cgcttcttac tgaaggactt agtatatgac cagcactatt
     9721 tacgcttgga aatcaattta aaacaggcaa cgaaactaga acttcactat gcgaagggac
     9781 ccgaccatac attactgctt aactatgatg ttgaacggga gtgctttact gcttccaggg
     9841 aacacatgcc gtatgattta tcaggagctg aaaaggaagt gttgaaaaag cgcagtgtga
     9901 cgattccttt ggaaaataat tgtctaacca tcgaaatttt ccgtgatact tcagctattg
     9961 agctttttct aaatgatcgt ctgactatga gtacaacttt ttatgagaca gaaaaaggac
    10021 aggattttct tttgctggca gacagtgaag taaccttttc attggaaagc ggcttaatta
    10081 atctatagaa gggagagctc agtgatgatt tatggttcaa tcgaagcagg cggcacaaaa
    10141 tttgtgtgtg ccattagcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
    10201 acgacacctg aggaaacaat
//
LOCUS       DACGLI010000081         9614 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.086, whole genome shotgun sequence.
ACCESSION   DACGLI010000081 DACGLI010000000
VERSION     DACGLI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.086"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            918..2459
                     /locus_tag="IXT22_002585"
     CDS             918..2459
                     /locus_tag="IXT22_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010632830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAQ4863904.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
     gene            2459..3211
                     /locus_tag="IXT22_002586"
     CDS             2459..3211
                     /locus_tag="IXT22_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4863905.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(3394..3969)
                     /locus_tag="IXT22_002587"
     CDS             complement(3394..3969)
                     /locus_tag="IXT22_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863906.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            4757..5329
                     /locus_tag="IXT22_002588"
     CDS             4757..5329
                     /locus_tag="IXT22_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HAQ4863907.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            5522..6085
                     /locus_tag="IXT22_002589"
     CDS             5522..6085
                     /locus_tag="IXT22_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4863908.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(6364..6651)
                     /locus_tag="IXT22_002590"
     CDS             complement(6364..6651)
                     /locus_tag="IXT22_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4863909.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(6641..6970)
                     /locus_tag="IXT22_002591"
     CDS             complement(6641..6970)
                     /locus_tag="IXT22_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4863910.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            7275..7604
                     /locus_tag="IXT22_002592"
     CDS             7275..7604
                     /locus_tag="IXT22_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4863911.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(7891..8376)
                     /gene="vanZ"
                     /locus_tag="IXT22_002593"
     CDS             complement(7891..8376)
                     /gene="vanZ"
                     /locus_tag="IXT22_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAQ4863912.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(8529..9440)
                     /locus_tag="IXT22_002594"
     CDS             complement(8529..9440)
                     /locus_tag="IXT22_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAQ4863913.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT         3231 a         1709 c         1586 g         3088 t
ORIGIN      
        1 tcaaaaaatc cctcctaaaa ttaatatact catagtttaa tatatacggg tttaattagt
       61 aagagaacat tttgtgaaca ttcttatatt gaaacggctc tctctacaaa tggacgcata
      121 tataagtgta tctgggttag taaacattca ctgttaccaa ctctacttac taaacagata
      181 aaatatcaac gaaataaaaa aaccaaatca actaattttt tactaataac gtagataata
      241 aaatcaaaaa gcaaatttga gcggttgcaa ctataaagtg acctgatgta aaccataaga
      301 tgcttaatta agctatactt agatgagaca ctatacttag gaagaactta gattagcata
      361 gcttcctaga acaaaaaaat acgagaggaa gattctttta tgactaataa atatctatct
      421 gtatttactt ttttggttgg cttgtttttt gttattaata gtgtagcaag ttctgatttt
      481 gatcttagta agattactct tttaactgta ctaccaataa taataggtag tgtgttaatt
      541 cttttttctg tgacttccct ttttagacag cgaggtaatt ccaaaaagca ttagcgaaaa
      601 agataaaagc agttttctct ttacccaaga gagaactgct ttttatcatc tccacatttc
      661 ttgcttaatt aattacagct tcataaatac tatcaatatg gctaataggg aaaccttcag
      721 taagggttac cctagatcct cctctagtgt aaccagtgat tacggcatcg aaaatgtacc
      781 atctctgcaa taatttttac caggctcggc aaagaaatgt accagtaagt gcaaagcagt
      841 gtaccacaaa tacctcttgt ataatgtagg tgcacacctt agggtgtgac atttatttta
      901 caggaggtat ttttattatg tttcgttatc gaaggatact tgaaatgcac agtgaaggaa
      961 ttagtattcg cagtattgca gcaagcacgg ggaactcacg tcagaaaatt actgaggtta
     1021 tccgaaaagc tgaggagaaa gggatagcga gggcgttgtc ggaagaaatg accgatcaat
     1081 ggctaggcga atttttgttt ccagaaaaac aattagaagc caatggacgg cacctgcctg
     1141 acttcgacaa gattcacaag gaattggcca aaccaaacgt gaccttgacg cttcttcatc
     1201 aggaatacgc agttgagtgt cgcatgagtg ggaaaatccc ttacgcctat cgtacatttt
     1261 gtgactatta caatgcgttc gcgcgaaagc ataaagccac tatgcgcatc cgtcggaagc
     1321 ctggtgaaat tatggaagtg gattgggctg gatcgccagc ttatgtcatc gatcgagata
     1381 cgggtgaaaa agtaaaggct tatgtctttg tggcaacctt accgtgcagc caattgtctt
     1441 atgcggaagc attcctaacg atgaaatcgg tggcttggat tacggcacat aaccatgcat
     1501 ttgaatattt tggcggttct accgacataa ttgttcccga taatctaaaa acaggtgtaa
     1561 aaaagaatga aggcatcgat gtcatcctta atgaatcata tcgagagcta ggggaacatt
     1621 acgggtccat cattttacct gcccgagttt ctactcccaa ggataagccc agtgttgaag
     1681 gcagcgtagg cgtcatctcc acttggatta tagctgcctt acgcaatacg cattgtttta
     1741 caatcgaaga tttaaatcgt gaaatcagaa tgaaattaaa tgaattcaat gagcgaccgt
     1801 tcactaagaa accaggatcc aggatcagag ccttcgagga agaagaaaaa ttcgcactta
     1861 atcctcttcc actggcacct tataagatgt ctgtctggaa aaaagcaaag gttcaactaa
     1921 actaccacgt ctcagttgaa agcatgtttt attccgttcc atacgaatac attcaacaaa
     1981 atatagatat tcgaatgaca gagaatctaa ttgaactata ttttaattcc atgcgaatcg
     2041 caacacataa acgtctgtac gggaaatttg ggcagtattc gactgtcaga gatcatatgc
     2101 cagataatca caaaatgtat gtggaccata ccccagaatc ctcgatggaa tgggctgaaa
     2161 ccatcggttc ctcaacagta aaggttgttc aacacctctt agaccgttat caaaatgaaa
     2221 aacaagcctt aaagtcgatc atgtctttga agagctttgg taaaaagtat tctaaaaatg
     2281 aaatagaaac ggcctgttca acagctttaa atctggcttc tttgccttct gttaaaatta
     2341 tccagaccat tctaaagggc aacaagcaga agcgagcaac aagccaatca catattgaag
     2401 acactaacat tgaaaagcat ggattcactc gcggtgcgtc ctattttgga gggaaataat
     2461 gatgttaaat gagcaaacag aagtaaaatt agctgaattg aaactttcag gcatgcttga
     2521 atcctatcgt gaacagatga caaataaaga gtaccaatcc atgagtttcg aagaccgctt
     2581 caacctcatg gttgatctgg agcattcccg gcgaaaaaat aataaactac agcggttgat
     2641 taaatctgca aactttagaa atgcctctgc cagcattgag gatatcgaat accatccgga
     2701 ccgtaattta gataagaacc tcattttaaa actagccagt gggacttatt tggaagaaca
     2761 ccataacatc attttgatgg gcgcttcagg gaatgggaaa acgtatatcg ccaatgcctt
     2821 cggaatacag gcatgccggc aatactacaa cgtgaaatac atccgactcc ctgaactact
     2881 agatgaatta accatctcga aaaatcaagc agatggtagt tttcgaaaaa taatcaacag
     2941 atataaaaaa gttcaattac tcatcatcga tgaatggcta ttaaccaatc tttcgttaga
     3001 aaattccacc tttctattgg aaataatcga atcccgtctt aaaacagcat caactatttt
     3061 ctgttctcaa ttccatccag aaggatggca cgaaaagctc ggcaaccccc aaatcgctga
     3121 tgccattcta gataggatca tacatgattc ttatcaaatt ctggtagacg gtaaagtttc
     3181 tatgcgtgaa cgttacggca tccgtaatta aatgagtcat taaaataaat taagagccac
     3241 tccatgattt tcatgagtgg ctcttagttg accttgtggt cattattgtc gcttttatta
     3301 tttgaaatgg taaccgcgtc gcacttactg gtacatttct ttgcacttag tggtaaaaaa
     3361 caatgctcta gtggtacatt ttcgatgccg tattcaacca gcttgaataa aggcactaac
     3421 acctgctgct gcatcatcgc aatggccaga taaataatcc cctgtaacca tgcctaataa
     3481 tactcctaac aatcccccag ctgtgccaac taaggtacct cctactttca aagcaccagc
     3541 attatacttc aactcgctac gcaatgcatt taatcctctg taagaagtag catatgagtt
     3601 aaccccacca ttcacaaatt tagttgtgaa agcatcttgt gaattaacaa cagctgtcaa
     3661 ttcagctcca tcatattttt cgactaaaga aaaaaattgc tcttcactaa tagaattatc
     3721 ttgactagaa gtagataata ctgattgtgt agaaaataaa tcagggactg aaacagttga
     3781 ttgattggaa gcaatcaatt cagctaactc ttcttcaaac tgaatgtaaa gatcattttt
     3841 tacaatttca taactaacag aatcttcctg tttttcagaa gctttggcta ttgtaggagt
     3901 aattaaggtc gatgtagtaa ttggcaataa ggctaaaata gtaaataaat acttaaattt
     3961 atttttcatt ttttatcctt ctttctattt tttctacttt taataccaca acttgaaaaa
     4021 taaaaaatct aagcaagagt aacatctctt acgtaatgat tttgcaatag tttttcctcc
     4081 tctcacaatc tattattatg tttttcgagc tgtttcaaaa gcacttttct atttacatct
     4141 gggaaactaa tcgttgcttt tataaaaaaa gatgatagca gaaaaaattg aacttttctt
     4201 tactataagg tatttataaa atcatcttca taggtcaaag tagtagtatt aatctcaact
     4261 ttgataagct ggtgtatatc aattttctct ttaatatgta caatcattaa aaatagattt
     4321 ttttactatt tatggtttca attaacaaaa gaacctccac actaaatcac tataaattta
     4381 ttatcacctt agttttttat gtgctcctag catggaaatc ccatcaaaaa agtaaggttt
     4441 gtattcaaat gtttttcgcc aacgagggta tcttcttttt tacactcttt gctgtatcaa
     4501 aatataactg aaattctaag tctcttctat atcagtgatt atgtgattcg aaatatccat
     4561 tccctcaaaa gaagttcata tagaaagtga atagagagtg gctcctgtaa atatgatata
     4621 gttaaactgg caaaataaaa tatgcttttt caaaaagtaa tatttttgtt ttaattacga
     4681 agaactactt ttaaatactg taagcacctt ggcttgttag ttaactattc ttaaaatgag
     4741 agggagacaa atatccatga ataaagctat attttgggat ctgttaggta cgctgggagg
     4801 ggatagtaga acactgatta atcaaaattt caattttttt aaagacacaa taccggcctt
     4861 aaaaaaagcg gcacaaagtc attatctaaa tatcatcatt acgaatcaaa gtcatatttc
     4921 acatggacgt attactatgg cagaatatac tgatgcctta gagagcttaa taaatgagtt
     4981 agagaaaaat gacattcaaa taacggatgt atacacttgc cctcatgcta gaaaagacaa
     5041 ttgtgattgc aagaagcctc aacctacatt tgtcaatgaa gcattaaaaa aatacgattt
     5101 aaatccaagt aagtgtttcg tagtaggcga ttccggtaaa aacgatatga tgttggccaa
     5161 aaatgctggt ataaacagtg ttttactttt aacgggagag ggaattgata gtttaaccaa
     5221 atatagacat ctgtggagtg aaacaaaacc tacttttatt gctgaaaaca gtttagatgc
     5281 tataaataaa atacatatgt atgcagatgg agactcttct gattcatgat accagaagag
     5341 tctccattta ttactaaaaa ccgtatcaaa aacaatcgat tatgagacaa aatgaaatga
     5401 cctcttttat taaataaaag aggtcatatt ttgtatcata acttgttgca ttaactatgt
     5461 atctataact cccttttatg atacaatcaa gccagaatta aagtacgaaa ggaagaaaag
     5521 catgagtgga tacatttatg gttatgcccg agtgagtaca cgttcacaag aactaaatcg
     5581 tcaattagac ttactcaatg aacaaaattg taatgaaatc ctaactgaga aaatgacggg
     5641 aaccaaagcg gttcgtcccc aactaaatcg tttaaaagat aaaattcgtc cgggagatac
     5701 ggtaattgta gaaagttttt ctcgattggg tcgtagtaca aaggatttga ttgaccttgt
     5761 tacctatttt gaagaacacc atgttaagct ggtgagcttg aaagaaaact tcgataccag
     5821 cacgcctcac ggacgcttaa tgatgactgt cttccaagca tttagtcagt tcgaacgtga
     5881 tttaattgtt gaacgtacca aagaaggttt gaaaagtgca cgtgcgagag gtcgtaaagg
     5941 tggccgtcca cgagtgaacc agaaagatgt tgatcgagca gtaaaattgt ataaaagtca
     6001 ggtttatagc gtaaaagaaa ttacggaaat gactggtatt agcaaggcaa cactctaccg
     6061 ctacttaaaa gacaataggg aataatctat tttaatcttt aggaatctat aatatttatg
     6121 ggagaattag agtgattttt ttattattac taaaaaacaa tataaaataa cgcattttaa
     6181 gccctctttg tgcataagga tgaagctttt aatttgaaag aggcttaaaa tgcgttttaa
     6241 ttttttctat ttttcataaa tatataggtt agtggtttaa aattataggg tattacaact
     6301 ctcagctgtt aaaaattatc ttttaaagtg tcgtctatcc tctcaagttg aaacattggg
     6361 ttcttaccta atctttttta attgttcata aaaattttca tgcgttccac atagtaagat
     6421 aggtatcact gcattatctt taatttcata tgcaacgcga tatgtcgtac ctgcatactt
     6481 gaatccaata gcccaaattc ctgataaatc acccgttttt tgttctcccg aatgaggacg
     6541 aactgctatc tcatcataaa ttatcgttaa aaattgttct tttaatgttt tctcttttaa
     6601 tttttttaga tactttatta cgtgtttaga aggtagaatc tcataagcca atttctgctg
     6661 ccaactcctc ttttgtcatc ggtttagaat ttgcaacagt atcttcagca atagatttaa
     6721 atgcagaagt taacgcattt tttctatttc taaattcttt taagatctct tgtttgctat
     6781 aaccttctga aagaatatca gccaaaatat cttcactaaa atcaaaaaat tcttttttag
     6841 gctctacaaa ctcataaagg ataccattct ctacaagctt agcttctact tcaacaccat
     6901 tgggcacatc gaattcttta gggaccgtta acataataga atttccttgt tttcttgttt
     6961 ttgtaatcat attatttcct ccattatttt acatttcgta attacttagt aattacattg
     7021 tacgctattt ttagtagaaa tacaaaataa taaaactcct ttagaacaat tttcaaagga
     7081 gttttatttg attaggaaat tatgtagaat aataatatgt ttttaacttg gaatcaaaaa
     7141 cgcacttgca agtaagttta cttcaataca tgaaattgct tataatagtg tattggaatt
     7201 aaggtagatt gacaaaagag tgatcaaata ggtatacttc attcaaataa tcgtttgaat
     7261 gtgaggtgag atgaatgaaa aaagtttgcc aagtgactgt cgtacataaa gaaaaagtaa
     7321 atggaataaa aaataaattg gatcaaaaag atttttcaaa cttacttgtg ttagggaaat
     7381 gtttcagcga tttttctaga attaaaattt tctatgcttt agaaacctat aaggaaatgt
     7441 gcgtctgtga tttagcagaa atacttactg ctagtgtcgc tacaacgtca caccatttac
     7501 gttttttaaa aaaacatgga atggcaaaat cacgtcaaga tggaaaagta gtttattact
     7561 ctttagcgaa tgaagacatc ctttccgcta ttcgtgtttt ttaaagttat cagaaaatct
     7621 atctatgaaa tcttagtttg ggggtaccgt caggaaaatg cggatttaca acgttaagga
     7681 aatttattaa agagaccaat tcctcagcac taaaattgat aattgggctt tctttgttac
     7741 tatagtgtta ggtaagcttt ttactttatc accggttttc ccctcacttc acacctacgg
     7801 gcgagtttcc ccacatcccg ttttccatct aatccaattc attcaatatc tttatgtgta
     7861 tgaaagatca gattgcttga tttagacatc ttacacgtaa tttattctta aatgggtacg
     7921 gtaaacgagc aataatacga gcaaaagtat acctacaaaa ataataactc tgtctaattt
     7981 tttttgattc atatgcttat tgcttaaacc atataatttc agtccaagaa agcctccaac
     8041 agtatttgta attacatctg ttatgtctgt cgctccaata gcgaagataa attgaattat
     8101 ttcaaaagta agacttaaaa ccagtacaaa agcaaactta ggtaaaaatc cgatttcttt
     8161 aaaattgaca ttcaaaagca agccaaatgg aataaagatt ataacattat ctatcatctc
     8221 tctgaaattc ccagtagcag taaatggagt caagttaaga cttctttgat gataattaaa
     8281 tactgataaa atattgtatt gtaatttgaa taacactaac cagattagtg tcactaaata
     8341 taaagctagc aatcctctag ataatatttt tcccaatata atttcctcta attcttttgt
     8401 ttaagttgta tcattagtat agcaatgtcc tagttaacgt gggttttaaa ttaaaaagct
     8461 aacgttaccc caaaagtgct agtacaataa tgctgttcat taatttcgtt ggtttcattc
     8521 cgccatcctt acctccttga attagtatgt gttgatccgg gaaacactgt cacaattaca
     8581 ccgtctatat tgtttcctga tatctcataa cgaagattag tcggcacatg aatggtggta
     8641 tttttagtaa caggataata aaagatctca tatttttccc catttacact aacagaaatg
     8701 gttttttctt cttttaggta atccatatat tcctcgagaa cgaaattctt ttctttcata
     8761 atcgcactat gtggtaaacc aacatagcga atatgccatg gttcatattg aattcctgtt
     8821 aactctgttt tgtcctctgg ataacgtaaa atgaacccgt atttccaagc attttcttct
     8881 atccactttc cttcaggggc tcgttccatt ttcgtcaagc ttgatcctac atctagtgat
     8941 aaacctgaat tatgctcact ataacctgct ggtaaggcat actcagcccc catttcttgg
     9001 taaagcacac tttgctcatc aaagtctcga tagccactat taataataaa atgactaacg
     9061 ccacccttta cagcatcatt gaccatctct gaaaattttt gtgctatttc ttttgacata
     9121 taaatattac tatcaagcaa cccgtatcca tttattaatt cgtcatgttt agataaattc
     9181 acgatatctg acttcacact ttcttggcga acaggatatt tactattgat taatagcaga
     9241 tttccttgat aaacctgttc ttctgtaatt gttttctctt gggtattttc agaagtccca
     9301 ctattttcta aatgttcttt gggattttga tcataatttt gaaattcgac tttttcctga
     9361 gaaaacagtg cttcattaac gtagtcataa cctaagtata ttaagaataa caataacaat
     9421 aaaaaaaaca acttcttcat tttcagtctc ctccttaact atatagttgg aagtatgaaa
     9481 tatttctaga atcttcccct taaacggcac aatctcgttt gagattgtgc cgttttgccc
     9541 cgtaaattac agtcaattat ttcgccctac tggatttact attatcacca atgtagatga
     9601 attttcataa gtga
//
LOCUS       DACGLI010000082         8948 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.087, whole genome shotgun sequence.
ACCESSION   DACGLI010000082 DACGLI010000000
VERSION     DACGLI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.087"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(15..1154)
                     /locus_tag="IXT22_002595"
     CDS             complement(15..1154)
                     /locus_tag="IXT22_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAQ4863914.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="IXT22_002596"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="IXT22_002596"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAQ4863915.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /locus_tag="IXT22_002597"
     CDS             complement(2967..3722)
                     /locus_tag="IXT22_002597"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAQ4863916.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /locus_tag="IXT22_002598"
     CDS             complement(3826..5016)
                     /locus_tag="IXT22_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAQ4863917.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="IXT22_002599"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="IXT22_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4863918.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7205)
                     /locus_tag="IXT22_002600"
     CDS             complement(6168..7205)
                     /locus_tag="IXT22_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAQ4863919.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="IXT22_002601"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="IXT22_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAQ4863920.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="IXT22_002602"
     tRNA            8802..8873
                     /locus_tag="IXT22_002602"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
BASE COUNT         2322 a         1897 c         1648 g         3081 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag ttttgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc agacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaagtctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaagaaaa
//
LOCUS       DACGLI010000083         8453 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.088, whole genome shotgun sequence.
ACCESSION   DACGLI010000083 DACGLI010000000
VERSION     DACGLI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.088"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..1329)
                     /locus_tag="IXT22_002603"
     CDS             complement(<1..1329)
                     /locus_tag="IXT22_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4863921.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIKPVVLVNFNILKNISKFL"
     gene            complement(1470..2072)
                     /locus_tag="IXT22_002604"
     CDS             complement(1470..2072)
                     /locus_tag="IXT22_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAQ4863922.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            2317..2523
                     /locus_tag="IXT22_002605"
     CDS             2317..2523
                     /locus_tag="IXT22_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863923.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            2835..3554
                     /locus_tag="IXT22_002606"
     CDS             2835..3554
                     /locus_tag="IXT22_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4863924.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(3635..4318)
                     /locus_tag="IXT22_002607"
     CDS             complement(3635..4318)
                     /locus_tag="IXT22_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAQ4863925.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            4536..6722
                     /locus_tag="IXT22_002608"
     CDS             4536..6722
                     /locus_tag="IXT22_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4863926.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7068..7478
                     /locus_tag="IXT22_002609"
     CDS             7068..7478
                     /locus_tag="IXT22_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4863927.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            7492..7848
                     /locus_tag="IXT22_002610"
     CDS             7492..7848
                     /locus_tag="IXT22_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAQ4863928.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3107 a         1382 c         1582 g         2382 t
ORIGIN      
        1 aaggaacttt gagatattct ttaggatatt aaaattaact agcaccacgg gttttatttg
       61 tatataaatc gtttgagaaa aacgctggtt ttcaattgat gtttcaagga aaagataagg
      121 attggtcttt gtcaattcat ccaagataaa caagccaagg ccttcgtttt ttggatttgt
      181 ttttgttgag aacccttttt gtttcaactg gtttaacggt aatgtatttg ttgttgtatt
      241 gatcacacga atcatcacgg aatgattctt cttgagtatg gtcaattcga tttttttctt
      301 ctttgcagca ctagctcctt caatcgcatt gtccaagata ataccaagca tacgtacaag
      361 gtttaccgta tgtttcgtat ccagttcgat tggctcagga aaatgaagct ggacgatcaa
      421 ccctttttcc tgtgccatca tgagttttaa tgacagtaaa ctacggatct caggaacttt
      481 catattatcc aacatactta gattggccgg aaaaaggttc atcatctggc gtgtaggtaa
      541 tatcgtttga tcataataag accgtaatcc ttctaagtcg ccttctgaaa tatagctgtg
      601 aagagaaaaa agcagatttt ggtaatcatg tttgaattct ctcaagtctt gatagttttt
      661 ttctagatct ttgatataat cctgttgcat cctgacttgt tgctctaata actgatcagc
      721 taatttctta ttagagattt tccaataata aaccaagatg atcaggccaa cacacagata
      781 tagaatgaaa aaactcgtat tcaaagctaa gacatcaggt gtttcaccag aaaaacgggt
      841 ataaaaaata atgatatagt atgtaaataa tatcaatgtc ccgatcgtac cgatcatacg
      901 gcggtccaca gtgtgaaacc aagtctctaa cgattttttt aaacaaaaag ctaataaagc
      961 agataaaaaa gcggataaga caatgtgaaa atactgcaat gaatctcctg gttcaataac
     1021 cgaagatttc aaaacaaaaa aatcgccgat gcttgttaag tgatctccta aaagcgacgt
     1081 caataaccca aaaggaagcg cgtaaaccaa ttgttgacgc gaagtcgaaa agaagaaaaa
     1141 agtaagcatc agcattccta tagcaattag agcagtaaaa atccctaaaa tcgaatagac
     1201 ccatccaatc aaaatacaag aaatcagaat gactcccgca aacagatatt tgtatcggat
     1261 gtgatggtca atcaataaga tacaaattgt gtaaatcaaa tattgcaacg ctatggacca
     1321 taaaaacata aagtacagct cccattgatt tttaccaaat tatagcacaa ttggcgtatt
     1381 atttttttaa tttttcaggg attttgaatt cagaactcat accaaagcag cagccagata
     1441 caaaaaagtc agataagtta gttaattgtt taatgattgt ttttttcatg aaagattcct
     1501 ccaaaattca tcaagtagtt tgtaatagga agcaacgtag ctatttctaa aacaatccca
     1561 agtagcaaat aggtagaaaa gtaagaagct gagaaaaata acgtaatgag agaaaaaatt
     1621 agaaacatgc tgatcgcctt ctttaataat gggggacgtt tctcgggttc aatgggattg
     1681 attgctgtac ctcttgatcc atagcgaagc agtaacaaaa agcagctgat taacaaaaag
     1741 accatcattg ggaaggagat agtcaattgc agatgtttca tcaccaaggg aacgccccat
     1801 aaataaagta gtgtccacag cagacaaacg aattcagagt cggaatgcaa tccataagca
     1861 tatctgcgga tgcagatata agaaagaaag gtgattcctg tttccgccca tgagcctgtc
     1921 accagagaaa agactagaac gaccgctagt tttccaagat tattcaataa aacttctaag
     1981 acaaatttta cttggacata caccatatct tcttccgatt tgtctccgct gaataaggct
     2041 tctaataatt tgttcacaac tttatctttc atctcatacg tacctccacc acaaatttta
     2101 tgctaaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac atcaaaaccg
     2161 tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa gtgacagttt
     2221 tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt atgttaaaaa
     2281 attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca attgtttgaa
     2341 gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa aggaaaaata
     2401 gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt agaagacaat
     2461 gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac aatagaagaa
     2521 taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt tagctctgag
     2581 ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc cttgtgaccg
     2641 aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga cttttgtcac
     2701 agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt agcttttaag
     2761 gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga agaacagatt
     2821 ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc ggtgcaggga
     2881 aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt tatgagaacg
     2941 tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat acttttttat
     3001 tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc agccatgatg
     3061 acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg aatgcagatt
     3121 tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa acgatgctga
     3181 aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat attcgtgtat
     3241 cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa cagctagaac
     3301 aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa gagtggtatg
     3361 aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat ttcgtagccg
     3421 atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag aaaatgacag
     3481 aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca aagggaatct
     3541 ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt tctctgtgag
     3601 cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga ttcgtatgat
     3661 aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa atggaaacga
     3721 tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata gctcctgcga
     3781 taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct ttttctttag
     3841 aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt gtaaataaat
     3901 tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat gcagtaaaag
     3961 caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta acaaagaaaa
     4021 aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct ttttttctaa
     4081 aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg gtagacaata
     4141 cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat agaatgatat
     4201 tgccagtttg agcagaggca aaagcaccat attggatata agtataactg tccatggctc
     4261 ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa gtctgcattt
     4321 ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac gattgaaaaa
     4381 aaggaaaaat tttcagaaaa ctaaaatcat atcgcttccc attttcattt ttagaaaggt
     4441 ctgttagtat aaagaaaaaa tagacaacga aactttaaat aaccaacttg aaataaacaa
     4501 attcaaagaa gaaagatggg aaggaaatca atcagttgaa tgaaaaagaa attctccgat
     4561 tacaaaaaga attgaaacgc tgggagaaca agtataaaaa gcttcaacaa gtctttcggc
     4621 tacaagaaga aatcattgct acctatgaag cggcttatgg cgaagcaccc ggacttattg
     4681 aggaagaagt acaagtaaaa gaaagtgaag gaaacagctc tttctttaaa atgatggaga
     4741 aacgttccta taatcgcttc aatcaagaac aaaaagcagc tatcacatat gatatgaaga
     4801 aacatcttcg aatcatagca ggagctggga gcggcaaaac gcaaacaatc tgtgcaaaag
     4861 ctgtttatct gatgacgcaa aaacaagtag acgaagaacg catactaatg atcactttta
     4921 caaggaacgc tgcaaatgaa ctaaaaaaac gagtagataa tttcagccag agaaaaaccg
     4981 ctgtccatat cggaacattc catagtatct tttttaggat atacaatgaa atttgtcgaa
     5041 aatttcctga agtagcaatg caaggaatac aaggagactt ttcaaaggat actgcacaaa
     5101 aagtgaatgc tgttttgcaa cagctgatac gtaaatataa tctttatata tttgatcaat
     5161 atggagaaaa aacgattgct tctcggttag actattggca gaatatgaac ctttcagtag
     5221 aagaaatggt tcagttagtt aaagaaaaat atgattccat tgataagaat gcacgacagc
     5281 cgatatcaga acgactgtat ggattgctca cggaactcca agaacaaaaa agaagccagc
     5341 aattgctaga gttcaatgat gtactccaaa atctgaaaag cgctttggag aatgaggaga
     5401 tccagcatta tatcggccaa aaatatgatt atctattcat tgatgaattt caagatacta
     5461 atccacttca atgggaaatc gtgaaacgga tgacaaagga aaacaggatc aagttgattg
     5521 ttgttggaga tgatgatcag agtatctatg gattcagagg atcagagcca gcatacatca
     5581 agaactttga aaaagaatat cctaccaaaa ctcttttctt attaactaat tatcgttctc
     5641 gggcagctat tgtccaagga gcaaatagat tgatcagcta taataaaaat gatcggatac
     5701 caaaggcgat gattccagca caaaaagaag caggtgttat ggaagcctat ttgttttctg
     5761 atactaaagc agaaagtcag tggctaatca aacaaattca gacatttatt caaaaaaatg
     5821 ggaaatataa ggaatcaatc atattatacc gatcagcttc acaaacgcag cagcttgtcc
     5881 aatctctgct gaaaacgaat attccttttg tactggaagc agatagtcca tatgaaggta
     5941 tctttggtat caagtctttc caacatttct atcaaaaaat tgttcattgg caaacagcac
     6001 tgaatctgca aaagaaaaat caggcctacc agcaattgct ccggcagctg atggcagact
     6061 gctacctgaa aaaaagtgaa tgcgatcaat acttttctcc taaatatcaa aatatagccg
     6121 ttgcagatta tattttgtcg ataagcccca atttaaaatc gaaatctgca gaaatccgag
     6181 agtttgagga agcgttgcgt aaaacagacc agcatcaaga aatctattcg cttgttcaaa
     6241 gctatcttca tctgccacgt atagctaagg aaatcgacca gagtgatcaa gaatggatac
     6301 gagaagaagt aaagcagcat gctactttca gaagactcca agccttatcg caagaaaccc
     6361 aagcgacagc taaagaatta aaaacccgct tgattgctta cagacaagga aaacttgatg
     6421 cactatgtat ccagagcatt cacaaaagta aaggtcttag ttaccgaaat gtctttttga
     6481 ttggttgtaa cgaaggaagt ttgccttata acggagcgac agaaaagaaa gtaatcgact
     6541 ttaatgaaat aaaagcagaa ccagtaacga cgatagaaga agaacgaaga ctattttatg
     6601 ttgcgatgac tagagcaaga aatcgtctgt atctatgtgt acctcaaatg aaaaattcaa
     6661 gaaaattgaa agtatcgaga tttatcaaag aaaccgggag tcgtgtgaaa aaaggaaagt
     6721 gatagaagag agggtgtgac agaagtggtc agtttcaaga aagaagaagg aatgtacgaa
     6781 aattgcttct caaatttttg tgaaatttca gcttattttc gaagaagcta tttctggaac
     6841 acagtttatt cggaaaaggg aggtgtgaca agaattttgt cacacctccc ttatttattt
     6901 tgaaaatgag aatactatta tcaaaataga gaatatatag aaaaattctc attattcaaa
     6961 cgtaaataat cagttatttt gatttttttt atattttatt agctaataat tggtatttta
     7021 aaagaaatta ctgtagaatt ggattataat taaaaaaggg tgagaaaatg ataaaagtat
     7081 atacttcgcc tagctgtact tcctgtagaa aagcaagagc atggttgcaa gcgaatcaac
     7141 ttgaatttga agagaagaat atttttgccg aaccgttaac agaaagtgag atcaaaaaga
     7201 tcttggcagc gactgaagga ggagttcaag atattatttc cactcggtcg aaaatttacg
     7261 aaaagctggg catagatttt aacgaattaa ctttaaagca aatgatcgtc ttattcaaag
     7321 aatatccttc attattgaga cgacctattt tgattgatga aaaaagaata ctaatcggat
     7381 ttaatgaaga tgagatccgg tcatttgtcc ctcgtgaaat tcgatgtgtt gccagaaatc
     7441 tgatctattt acaaaacaat aacatcttaa attcataggg agggagcctt cgtggaagtg
     7501 aaagtctatg gatcagcgca ctgtgtaaca agtctgaagg cgaaacaatg gttagaacac
     7561 catcaattgc cttatcaatt tgttgactta gaagaacgcg atctaagtac agaagaagca
     7621 gaagaattat gcagttttga agaagtgcaa gcagaacagc tatttgcgac ttggtctgag
     7681 gcttttcaca acattgcgat tgacctttcc tgtgtaggaa aaaaacaact gattttttta
     7741 tgcacacaac ataccaatct cctcagacgt cctttgatta ttatcgatga agttctattt
     7801 attggataca atgagcagtt gatggaacag cttatcttaa ataaatagac tttaactgtt
     7861 ttaatcaagt cactgagcat ttcatacagt tgtaacagtc gaacacttag catcaagcgt
     7921 gttatgtgtt ctttttttga ctttattttt ctactataga gacatgctca atttatgtgg
     7981 tcaaaattca aatctaggtg gggatataga gttaaaaata tattgacatg tgtaaattta
     8041 catgatatat tcatttctgt tgttttaagt agcaaagcaa taaaatagta ttttaaaaaa
     8101 catataaaat agttgttgac atgttagaaa tgacatgata agataactga gttgttaaaa
     8161 aagaaccact tgtgaagctt gattctatcg aaaaaaactt caaaaaagtt cttgacaaat
     8221 aacaaatgat aagttatgat aaatgagttg ctgtaagatt tcgaaaaacg aaatcaaaaa
     8281 aacttttaaa aaagagttga caattacttg tctctctgat atgatataaa agttgctacg
     8341 gcagccaaaa acgaatcggg gaacactcct gatgaagtag acctttgaaa actgaacaaa
     8401 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa aca
//
LOCUS       DACGLI010000084         8303 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.089, whole genome shotgun sequence.
ACCESSION   DACGLI010000084 DACGLI010000000
VERSION     DACGLI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.089"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..3085)
                     /locus_tag="IXT22_002611"
     CDS             complement(<1..3085)
                     /locus_tag="IXT22_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAQ4863929.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQE"
     gene            complement(3099..4316)
                     /locus_tag="IXT22_002612"
     CDS             complement(3099..4316)
                     /locus_tag="IXT22_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAQ4863930.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(4306..5901)
                     /locus_tag="IXT22_002613"
     CDS             complement(4306..5901)
                     /locus_tag="IXT22_002613"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAQ4863931.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYSISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6026..6811
                     /locus_tag="IXT22_002614"
     CDS             6026..6811
                     /locus_tag="IXT22_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HAQ4863932.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
     gene            7520..7879
                     /locus_tag="IXT22_002615"
                     /pseudo
     CDS             7520..7879
                     /locus_tag="IXT22_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2448 a         1651 c         1395 g         2809 t
ORIGIN      
        1 tttcttgtgg gtatttaaat ggtttcgctt ctggatgttt ggctttatat ccttcgtaat
       61 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      121 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag gcatgaatca
      181 aattatcact tgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
      241 ctaaagtccc cacatcaaat gcatttaaaa tttgtcggta aacttctttg actccttctg
      301 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgcag
      361 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttagtggtat
      421 tttcactata aaattcgatc gttgaaaaat cttctccctc tttttctggt tcttcctcca
      481 tcaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
      541 tgttcaaagt tgaagattgc accatgtcat cattgtaatc atcataagtc actaacgatt
      601 catacgcacg attcaattct tgaaatgctt tgacgtactc gatacggatt tcaagtggcg
      661 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
      721 atcttttttt ggattcttgg taacttggat aaatcaaacc cgattcttct ttagcttctg
      781 aatacagttt tgtcgcatcc tcgacattct tctccattgt cgctggcttt cggaaagtaa
      841 caattagtcc ttttgttttt tcaggatacg tacggttcgt acgtgaaaag gcttggatca
      901 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggg gcgtcaaaac
      961 ctgtcaatag acgatccact acgattacta aatcgatttg tttcccaaat tgtttgaatt
     1021 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1081 gtgaccaggc agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1141 gttgggcact tgaatctcgg ctattttctt ctaatgaata ggtaatagcg attcgtggga
     1201 aatcaggatc ctccatcgtt cgtccttcac ggataggctg attgggaaac tcttttatta
     1261 accaatcaga ttctttcgtc atctctttga tggcccgata atactttttg gccatatcaa
     1321 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     1381 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcctctgctt
     1441 caaaaacagt agggtccaaa taactttctt ttttgacaga ctccatttga tcgatcatac
     1501 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     1561 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     1621 ccgagccatc ttctaatgca ttcttgatgg tataggtgtg caagacctct ccatactgat
     1681 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     1741 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     1801 cagcacttaa cgctcgatga cactcatcaa ctacaaacac gatatgttgc cccattaatt
     1861 tttggaagcg attggttcct tttttctctt cctgtttctt tgcatatttc aacgccgcat
     1921 ctagtttttg acgggttgta atgatcacaa cattcgcatt ggcatctgcc aacagagttt
     1981 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcattaccag
     2041 aagaaacccc agtattaaac tccgaagcaa atttcgtaaa ctctgtggtg gtctgattat
     2101 ctaaatcttt gcggtccact aacatgatcg ttcgatcgat ccccgatttt cgtgctaaaa
     2161 gcttagtaga tacaaaacta gtcaacgtct ttcctgaacc agtcgcatgc cacacatacc
     2221 ctgattgatg tttatttgcg gcaataaaca aggcttgaat cgcatgcact tgataaggat
     2281 gtaacaccat gagggtttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     2341 agcgatgggc atctgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     2401 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc ttcggtaagg
     2461 catttgcaaa ataccgagtc gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     2521 agatattgtt ccgaaacatg ccttcttcag catatttttt gatttgatta aacgcctgat
     2581 aaaaaccatc ttttgcagtt acttgtttta gctcgatttg gataatcggt aagccattga
     2641 tcaataaggt gacgtcaaaa cgtcgatccc gcgcttctat gttacttcca cgttttgcaa
     2701 tttgatggac cacttcataa gtagagattc ctccaccaat gtcttgattg gaataaagga
     2761 taagtgagac agaacccaat tgcggatttt cccgttcaat cgtgatccga gccatcccat
     2821 tttcaccttt taaccatttc gcagcatcaa atggggtttt cgtccgtagc aataattcgg
     2881 ttttgatcgt ttcaaactct ttatcggtca aaggagaatc attcagttct gcttgattat
     2941 ttgagatgat tttttgacgt aaattgctcc aaagatcttc ttctgatttt agatccggac
     3001 gatacgtcca ctgattatgt ccttccccga ggacacgaat caactgttct tcgacttccg
     3061 cttcctcacg gtgactaatt ttcattcttc ttccctccct aaacaaacat cttttgcaag
     3121 aagccttttt tcgtttcctt cagcaaatct aacttacgtt gatgaagagc gatcgtatca
     3181 tctagctgct tgaagaaggc accaattttt tgttgttcat ttatatccgg tggaaactga
     3241 aatgtccttt gttctatacc acctttagtc acatgtacca ttgtcgttcc gttagttgat
     3301 tctttaattt tctctttatc agtcaatagc caagtatata gatactgttt gtccaattcc
     3361 ttagataaaa atttaagttt ccaaatatga taatggtaga ttacacgttc ttcattccac
     3421 atttcaggac cgaagcttgt tgcccataaa tataagagat ctcctttatt agcatacttg
     3481 tcttcctcta attctaagtt tgaataatac catctatcat tagtattaaa attacctact
     3541 cttaaaaccc tatattttcc agaatcaagt aattcttgtt gtttaaaagc tctaccattc
     3601 aaaaaaacta ccacttcccc caacttccgc tcttcccaat ctcccgtaaa tcctggaaaa
     3661 cgaacttctg gcacttttgc tccgttttta gggaacattt tttgtaagaa tccttttttc
     3721 gtttccttca gcaaatctaa ttcgtgctgg tgaagcatga tggtgtgatc aagttgtttg
     3781 aaaaatgaac cgatcttgat ctgttcgtca taagttggaa gtgagatagg tgtcttttta
     3841 ccactatcaa ttgtataggt tccgacggtt ccaatgcctg caacgtcacg gatatacttc
     3901 tgaattttgt tatttatgaa cgagtagtaa aagaagtttc cgtcaatttt atgctcattc
     3961 ttgaaccaaa tgatgtttcc atccttaaag taaattgggt tatcatcagt gattaataag
     4021 gggacaccta ttgatccgac accagttaca agcaagtctc cttgagaaac tttacctgaa
     4081 tttttcgaat attcattata tttttcttct gaaatgtaaa gataatcgga tggttcctca
     4141 ttttttgcag ctgagacaat atcacgagca cgtaaaaatc taatacctga gttagtccaa
     4201 tctgattgat gaattcgctt cacagaagta acatccatca tatctcctaa cttacgctct
     4261 tcccaatctt ccgtaaaacc aggaaaccgg atttctggtc gtgtatcatt gctcatgttt
     4321 gaacacctcc agcgcacctt gtaaccacgc ttcattttca ggtgttgttt gcagggaaga
     4381 gatagcttct aaaagttctt tttctagcac ttgctgttct tgtcgtatct tcttgatgtc
     4441 atttccgaca tgaaccatat caattggttc ttcttcttcg aaagtatcga catagcgtgg
     4501 gatatttaag ttatagtcat tttctttgat ttcatcaaag gttgccaaat gagcgtattt
     4561 ctcgacatct tttctttcag cgtaggtttc gaggattttt tgaatgtttt cttccgataa
     4621 tttattctga tttttccctt taacaaattc acgactagca tcaatgaata atacatctcg
     4681 agtttgacga ttcttcttca atacaatcac cgtcgttgga atcgatgtac caaagaacaa
     4741 gttcgcaggc ataccgatca cagcataaat actgccgtct tctaataatt tttgacgaat
     4801 gaccccttct gcagcaccac ggaataaaac cccgtgtggc aagacgatag ccatagtccc
     4861 tgtttccttc aaatgataga aaccatgaag aagaaacgca aaatctgctt tggattttgg
     4921 cgctaatttc ccgtagcgat taaaccgaga atcatctaag aaggtcgtat ctgctgacca
     4981 attagccgaa taaggtggat tcatcactac tgcatcaaat gtgtaaggtt catctgttgg
     5041 ccagtcctta ttcaacgtat ccccattgcg gagattcatt tcttcggcat ctaccccatg
     5101 taaaatcaag ttcatttttg ctagattgta tgtcgttgta tttagttctt gcccatgata
     5161 tttaacgtta tctggatgag ttaagtagtt acgtacattt aacatcaagg aacctgaacc
     5221 catggttggg tcaaagacac taaagaatcg tcgttctttt tgatccaacg tcacgatttg
     5281 tgccatcata tcagaaacca tatgaggcgt gtaaaattct ccggctttct tccctgcttc
     5341 tgaagcaaat tgactgatca gaaattcata cgcatccccg atcacatccc catcgtgacc
     5401 taaaacttcc acgtcattca atttcttgat aacttcggta atcgtcacat ttcgttgttg
     5461 ctcatctgtt cctagttttt ttgattggag atccacatca tcaaataacc cattaaattg
     5521 attgtaggta gatgccaatt gcacaaaggc tttgtttaga tcgttcaatt ggaacgttgc
     5581 ttgttttgct tgatccgcta agacgttgaa aagatactct ggtgagatcg aataccccaa
     5641 aatatcaacg attgtggcaa tcaggtcttc ttttgattct tcatctgaaa gtaattcacg
     5701 atacaacatt gtttgtttgc ttactgtgtc atattcctct aaggattcat ctgctaaaag
     5761 aaccacttgt tccaacaaac ggtcggataa atatttatag aaaatcagtc ccaataaata
     5821 atttttatat tctgacgcat ccattttact acggagatta tctgccgcac taaataattt
     5881 ttgatttaat tctgcaccca aaaagataca ctcctatctc ttatttaaag ttgctatata
     5941 ccctcttatt ttagcatact cccttttaga aaaagcaaaa aaaaaagaaa aaatcttatt
     6001 cttgataaca agctacgtga cgtatatgcc taacaaaaat agaacttttg aatcaatctt
     6061 aaatgaaggt ttaaccacag aaccggcatc cattattttt gatgaagtta tcgatgacgt
     6121 tgaagatagt aagtatcata aaaatttaaa agaacttttt tattttgcac tcaacaatgg
     6181 accaagtttg ttcactggta tatcagtacc tgatagtgat aatccattaa ttatggcaaa
     6241 aatttactta acaaaatggt gtaataaata catcagggat aggaataacc cagcattaaa
     6301 aaaacctctt aaaacatttg gcgaaaaaga tgctgcttta actactagag tagcagcaaa
     6361 tgctaatatt gatgatcaaa aagtattgaa tgactacttg cgtggacatt ttttatatat
     6421 gagcgctgag aacatgaacg gaagtatttt agaggaatat ttagccgaag tgttagaacc
     6481 tgaaggttgg atttggtgcg ccggctctgt atatcgagct gttgatttct gttatttagg
     6541 aacctcacca attcttttac aagtgaaaaa taaatacaat acagaaagca gttcgagttc
     6601 agctataaga gtaggaacaa caattagaaa atggaatcgt ttaaataagt cgacaaaaat
     6661 ttctggtttg gatagcccta tccccaattg gaaagcatta atagaaatga ctgaagctag
     6721 taaggaactg gcagctaagt taactgaaaa tagttattta gcttatatta atgaaaaatc
     6781 cacacgagaa ttatggacac tcgatgacta acaatatcct tattagtatc tatccacgat
     6841 acatggaaaa aattataaac aaacaaaaaa actttgaatt tagaaatttc tatcttacct
     6901 cagatcctta taatatcttt tggatttacg aaacaatccc caccaaagct ttaaagtata
     6961 aattgattgt aaaaaatcca attactaaac ttaagaaaaa tcaacactac tttttaggag
     7021 acgatgagtt tgaacaatta gtttaaaagg gaaaatatgc ttctatcatt acaagctcgt
     7081 ttggtgtaag atgggtataa gtcatttatg ttcactctcc ttgtatgctt tagcgggtat
     7141 tacaatttga gtgtaacata aatggctttt ttatttgtct cgcttaatta tacaaacggc
     7201 gaattataaa taactcataa aaaatatttt gactttcaaa atcacttttg ctaccagaag
     7261 ttgaggcgaa gtgttttaag catagttgta ccctagtttg accgttaaaa ataaataacg
     7321 atcgctagag tgcaactatg tttgtttgcc ctaccgtcag cgtcggcttg gcctctcaca
     7381 tccattaccg tcgggattat ctccgttaca tacccttaca aaatacgccc tgtaagcatt
     7441 gcatgaaacc accgtgcatt tgcaccgtat ttccgcccta gccgttcaaa tcggtcgcta
     7501 ccaccattca gaaacacgtg cggtaatgga aggtttggag gaagctatcc agaccactaa
     7561 cgattgtccc tatcgtcgta cgtttcactc agatcaaggt tggtcgtatc aaatgaaagc
     7621 ttatagaaac aaattgaagg agtacaaaat ctttcaaagc atgtctcgga aagggaactg
     7681 cttagataat tcacttatgg agaatttttt tggcttatta aaacaagaga tttttcacgg
     7741 gaaagtttat aactgtttcg aggaattaaa atcagccatc gatagctata tctattacta
     7801 caataatgaa cggataaaac agaaattaaa ctggcaaagt cccgtccaat ttcgtaaaac
     7861 aaccgttacg gttgtgtaaa aatatcattt tagagcatga aaaaaagagt ggatttctcc
     7921 actccaaaaa agtctaactt ttgggggtca ctacattttt gatccttttt atttgattaa
     7981 ttatatccag ctggataata attttggggg caacatttct atcttactat tatcttccta
     8041 aagtagtaga ctttcttatt gggaaaaatt acaacaaaaa ggagtggctt agttgacaac
     8101 tcctttttgt ttacaaatca attggatatc tataaattgt attttctaac gaattttata
     8161 gacatctgat ttgtcaaatt aagctagaca atatgtcttt atctatgcag ctcaaaaata
     8221 cttccaatgg tgttcgataa tttaatgatt ttcttggaat atggtttctt ttcgaggcaa
     8281 cggattgaat aaaggtttca tcc
//
LOCUS       DACGLI010000085         8229 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.090, whole genome shotgun sequence.
ACCESSION   DACGLI010000085 DACGLI010000000
VERSION     DACGLI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.090"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="IXT22_002616"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="IXT22_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAQ4863933.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="IXT22_002617"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="IXT22_002617"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAQ4863934.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="IXT22_002618"
     CDS             2591..3376
                     /locus_tag="IXT22_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4863935.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="IXT22_002619"
     CDS             3389..4240
                     /locus_tag="IXT22_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAQ4863936.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="IXT22_002620"
     CDS             complement(4364..4816)
                     /locus_tag="IXT22_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4863937.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="IXT22_002621"
     CDS             complement(5281..5649)
                     /locus_tag="IXT22_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAQ4863938.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="IXT22_002622"
     CDS             5799..6281
                     /locus_tag="IXT22_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAQ4863939.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="IXT22_002623"
     CDS             6318..7328
                     /locus_tag="IXT22_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAQ4863940.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="IXT22_002624"
     CDS             complement(7443..8156)
                     /locus_tag="IXT22_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863941.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2441 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtct
//
LOCUS       DACGLI010000086         7911 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.092, whole genome shotgun sequence.
ACCESSION   DACGLI010000086 DACGLI010000000
VERSION     DACGLI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.092"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..1023
                     /locus_tag="IXT22_002625"
     CDS             <1..1023
                     /locus_tag="IXT22_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4863942.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1034..3043
                     /gene="topB"
                     /locus_tag="IXT22_002626"
     CDS             1034..3043
                     /gene="topB"
                     /locus_tag="IXT22_002626"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4863943.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELYSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            3389..3985
                     /locus_tag="IXT22_002627"
     CDS             3389..3985
                     /locus_tag="IXT22_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4863944.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3998..4897
                     /locus_tag="IXT22_002628"
     CDS             3998..4897
                     /locus_tag="IXT22_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4863945.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4900..5031
                     /gene="ssb"
                     /locus_tag="IXT22_002629"
     CDS             4900..5031
                     /gene="ssb"
                     /locus_tag="IXT22_002629"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4863946.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            5053..5385
                     /gene="ssb"
                     /locus_tag="IXT22_002630"
     CDS             5053..5385
                     /gene="ssb"
                     /locus_tag="IXT22_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4863947.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            5407..5664
                     /locus_tag="IXT22_002631"
     CDS             5407..5664
                     /locus_tag="IXT22_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863948.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5823..5945)
                     /locus_tag="IXT22_002632"
     CDS             complement(5823..5945)
                     /locus_tag="IXT22_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAQ4863949.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            6135..6359
                     /locus_tag="IXT22_002633"
     CDS             6135..6359
                     /locus_tag="IXT22_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863950.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRNQLVIESMQIRNPDHFTRLMGI"
     gene            6807..7013
                     /locus_tag="IXT22_002634"
     CDS             6807..7013
                     /locus_tag="IXT22_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4863951.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7013..7264
                     /locus_tag="IXT22_002635"
     CDS             7013..7264
                     /locus_tag="IXT22_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863952.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            7280..7717
                     /locus_tag="IXT22_002636"
     CDS             7280..7717
                     /locus_tag="IXT22_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863953.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            7710..>7911
                     /locus_tag="IXT22_002637"
     CDS             7710..>7911
                     /locus_tag="IXT22_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863954.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNN"
BASE COUNT         2869 a         1374 c         1661 g         2007 t
ORIGIN      
        1 gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg tttagatcat
       61 gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc aagttatcaa
      121 ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca cattgacaag
      181 aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca tttaaaattc
      241 tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa actacaagat
      301 gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta cgttgaagag
      361 tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat atgtgtggac
      421 aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat cgttgatcct
      481 tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca agtacctaaa
      541 gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc tgaagcaatt
      601 atggccatac acaaaactga aactaattta cagctgacaa atcaattggt gtctgctcat
      661 gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga aacaattgat
      721 ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg cgcagatgga
      781 acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt taatgcagga
      841 atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca tgaacatgaa
      901 tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat ccagcaacaa
      961 gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca agaaagggag
     1021 tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag cgaaggctta
     1081 tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc aagatcgatt
     1141 gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt tatattcgcc
     1201 cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta ttttccccaa
     1261 tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg tcaaacgaca
     1321 gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag gggagctgat
     1381 tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta aaagactttg
     1441 gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac gagacgcaga
     1501 agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt ggttaattgg
     1561 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagttt
     1621 ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc aggaaaagat
     1681 tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg ctcaaaatgg
     1741 cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag catttgaagc
     1801 ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc ttcaagtcga
     1861 aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc ttcagtctaa
     1921 aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc aagggttgta
     1981 tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg aaggggaata
     2041 tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg aagcgattcc
     2101 gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc aggaacatta
     2161 cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac taagtccact
     2221 gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg cggaaaagta
     2281 tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa aggcaatcga
     2341 aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg acggaaaaga
     2401 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtggatct
     2461 acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     2521 tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     2581 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     2641 ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga ttttgctttg
     2701 ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca aatgggaaag
     2761 ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag ccaatatcca
     2821 aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca ctgattttgg
     2881 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     2941 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     3001 gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg attgttttaa
     3061 aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa
     3121 gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc acacacaaac
     3181 aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca
     3241 gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa atcgaattag
     3301 atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact gtttttataa
     3361 gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca agctgctaga
     3421 agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt ctcctgtaac
     3481 gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt ttttcacctt
     3541 acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac gcggcattat
     3601 ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta gacagatcga
     3661 tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat tcgcagttga
     3721 gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa aaagtcgcta
     3781 tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt ggaatccctg
     3841 gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg agtcggacag
     3901 aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca aaacgatgcg
     3961 ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc agttaaaagc
     4021 aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt taagacattt
     4081 tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa attttgtgtt
     4141 aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa ccaaagatat
     4201 tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg ttctaaacga
     4261 aattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa tgaaagaaac
     4321 gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt tggaaaacat
     4381 gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg caacgatcac
     4441 tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct atcctacaga
     4501 acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata attcgagagg
     4561 aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg agaagacctt
     4621 gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt taaagatata
     4681 ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata cctggaagaa
     4741 atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa tggattcgat
     4801 tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac tagcttatca
     4861 aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa tgtgacatta
     4921 gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac tgcagtagcg
     4981 acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg agaagccgat
     5041 tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt agctaaaaaa
     5101 ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa ccagcaagga
     5161 caacgtgtat atgtgactga agttgtagca gataactttc aactattaga aagtaaagca
     5221 gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac cgccaccttt
     5281 gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca gaatccattt
     5341 ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga gaaagaagga
     5401 gtaagcatgg caaaaaaaat tagtctgacg atggatctat tgatacccgt aattgcattt
     5461 atagacggga tttctttggg cgtcactgaa aatcctttgg taaatagaat tgcgaaagga
     5521 tcactatttc ttgtattcgt gtatcttgtc tgttcttatc ttttaaaaag agcaggaaag
     5581 gataattcct tttggcgatt gactaaagtc acagtagcag cgacagctgt tatacttacg
     5641 gctattctac cgctttatat gtagagttaa cgggaaatcg ttgaacttct tgcgaaatat
     5701 tgctataatg aacatgaaaa agaggagttg cgctaacaac ccctcattaa cagcaccgat
     5761 taaagaacgg tggcagaata ttagttattt ggaaataacc gctgacctgc taaagtagac
     5821 ggttatttct ttttgtcatt tttaagcata tttacaatca aactaatcaa agcaatggta
     5881 aacataccaa aaccaagaat ggtttgaatt gtctcatatg cggacaaaag gcttactcct
     5941 ttcatagatt ttagcactta cattcataag caccaccacc tttccagaag tcgccaccgt
     6001 cttcaaactt tactgtcttg actattatag catatctaaa atcgaataaa aattctcaat
     6061 tttagctgtt tttgctataa ttttagcgag gtgatcgtga tggaacaata tattggttta
     6121 ctcgataaat tagggtgatc aagacacagc cattgcttgt gcgatttaca ttacgcacga
     6181 gtcatgaacc aatcaattgt gtagtggcca atatagaaat agcggataaa ttgctgattt
     6241 tggaagaagg caagtatact atttcagtga caggtcactt caataaacga aatcaactag
     6301 tcattgaatc aatgcaaatt agaaaccctg atcattttac gagattaatg ggcatataaa
     6361 taaaagaaga gctgcagtcc taaatgagga ttgcagctct ttttgtttta catagaaaca
     6421 agaaaaatga aaaggccttt ttaggaaggc gcaagcgcct tctcaattga aaaacctctc
     6481 tctcactcca accgccaccg ccgttcgaga agaaaggaag tgaacgttgc acgttcacta
     6541 agataagggg tcttgcaaag caagacaaaa tagaaaaaac ttcctctcac caaaaggttc
     6601 gttcctgttc gctatctctt tattgatttg ccagaccggc aacaagttgc cttttatcac
     6661 caaaaagcga caaggacaag ggtaaatggc acgctgcacg cccttgtcct tgtcgctttt
     6721 agttgattca ttctggccaa caaatcaata aagaaagaac taacgaaagg aagtaaaacc
     6781 tttcctaaga ggaggcagaa tcaatcatgc gaaagaaatt tgattattgg ggtgttccct
     6841 tcagcgaatt attcccaaac tatcatgcac catatactgt cgaatgcgat tgtggagaaa
     6901 gagcgaaatg tatcaaaagc tattgtttgt atcaatgtcc aacatgcggg aaaaaatata
     6961 ccttgtctta tggcgattat attttgattg atgagaaagg aaagaaacgc tgatgaaaac
     7021 acaacacaaa ttattgactg taaaagaagt cgttcaaatt ttggtggaca aagaagtcat
     7081 ttctgaaaaa gtagcagaag ctttacttat tccgcggtac tggacgatag aaaccccttt
     7141 agtagaggat gcaccgacta tgctatttga agacctagtg aagattgcag gatatgaact
     7201 gcattatcaa gaaaacatgg aaacttatga aaacgaatat tggttaacca aattagagaa
     7261 ctaaaaagga gaaaaaaata tggctcaaaa ttactatgac gaatttgtca aattaccttt
     7321 ggataaaatg gcacaaaaaa tggaggatat gacattccta tacaatgaga cacgtgttcc
     7381 aaaaaaacat tataaggaaa gattgtcggt agctgtggaa gaaatgattg aatcgggtgt
     7441 cgaaatgaat ctcattgcga cctactatcg aacgcttgaa gaactgaaaa agcaaaatgg
     7501 acaatggttt ttccaagcct tactatgctt ggaagcaggc gtcaagccaa acactatcaa
     7561 accttctgaa taccaagctt tagaactaac gtatgggaaa tttgtcgaaa cgaaaaaagc
     7621 caagactgtt tcaagtgaat ggttggacta cttagaaaat gtcaacaagt atggcgcatg
     7681 ttacatcatg aaaaaggagg acaacgaaaa tgaataaggt gatttatcaa ctaacaacgg
     7741 aagatgtgtc acacttttta acaaacaaag aacatttgaa tgaagtaatc agacggattc
     7801 aaaaagactt tagttgtatg gaagaaatga agtactttat tcaaagagtc gaagaacaat
     7861 tgtatttgga aagtgaaacg agtcaaacga aggttacagt cagcaataat t
//
LOCUS       DACGLI010000087         7907 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.093, whole genome shotgun sequence.
ACCESSION   DACGLI010000087 DACGLI010000000
VERSION     DACGLI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.093"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..199)
                     /locus_tag="IXT22_002638"
     CDS             complement(<1..199)
                     /locus_tag="IXT22_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863955.1"
                     /translation="MKKMGKCILCEKYTQLTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
     gene            complement(362..1996)
                     /locus_tag="IXT22_002639"
     CDS             complement(362..1996)
                     /locus_tag="IXT22_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4863956.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            complement(2000..3373)
                     /locus_tag="IXT22_002640"
     CDS             complement(2000..3373)
                     /locus_tag="IXT22_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4863957.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            complement(3389..3628)
                     /locus_tag="IXT22_002641"
     CDS             complement(3389..3628)
                     /locus_tag="IXT22_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863958.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            complement(3810..6485)
                     /locus_tag="IXT22_002642"
     CDS             complement(3810..6485)
                     /locus_tag="IXT22_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAQ4863959.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            complement(6668..7591)
                     /locus_tag="IXT22_002643"
     CDS             complement(6668..7591)
                     /locus_tag="IXT22_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863960.1"
                     /translation="MATNYAKKINFDVDKLYKSLIVVPKNKSEDGNYELEVLQFKIEQ
                     KSSERFMSNQLVKIKKWLPMIDQLVSNNKEAKNLCIFVLLLHGRVINLVNRKSTTKFA
                     NSFWFLKNINKTVEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNETY
                     SQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETLRI
                     LKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEPLK
                     CRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
BASE COUNT         2306 a         1555 c         1207 g         2839 t
ORIGIN      
        1 tataataaac atttccttga ggtttccttt taatcccctt cggaaaatca ccttttgtaa
       61 aatcgctctt aaggaaatca tctaaattac cagttctggt ctttttacct ccagtattcc
      121 ctgatttttt aggtggtaca tgttctttag taagttgagt gtatttttca cataaaatac
      181 acttacccat ctttttcata tctatcccca ctctttttaa ttcttatata caattatatt
      241 tcaaatattc attaataaat atccctattt atgataagga cctccctaac tacttctcta
      301 acgatttcaa atcgctagag aagcgttagc gcccctctaa cgttgtttga tataacctag
      361 actagatcgt taacgtaaag ggtgttttta acacaaaaat agccgtatcc tttgttttgg
      421 atacggctat ttgatattgc tcattcaatt gttgtaccac ggcatgcgtg aatttcatcg
      481 taatttccaa catctcctta tggttaggat caaaggttat tttctctata aaggtacgat
      541 acaaggcttt gatttgcttc ttctcactct gggcaagaaa acgatccaaa ctagtcaata
      601 tccgttggac atctttgact tgaatcggct ctccttgttg aaagatccct aagatttcat
      661 tttctcgaat gtgcaactgt cgtcgttttt cagtcaattc gtctaagcgg tcttttaaca
      721 tcggaaacaa ttcaggacta tcttccaaag cagcttccca tttttcaatt ttagtcttca
      781 attcttcctt tcgttccagt aacaccacga gttcttgttc caatggttgg ctttgtcgca
      841 ctatttcttc atttaacgct gccaccaatc ggggaagaac ttctggtagc tgaacgatct
      901 cctttaatcg gtcggcgaca aatgtttccg cttgttcggc acgaatcgaa ttggcatgac
      961 acacacttgc tcctttattc cgaaagactg aacaagaata atatcgaatc cgtttctttg
     1021 tgccatcctt tagggtattt gtgacattac tcgctgccat cggtgcgcca cattctggac
     1081 aacgtaacaa gcctgtcaat acattttcac ctgtatggtt ccatttgggt tgttttcctt
     1141 ctaaagcaag gcgttcttgt actttttgat aatcttcttc cgaaataatc ggttcatggg
     1201 ttcctttcac taaaatcggt ctcggattct tccccttccg tcgtttggtt tcccaattga
     1261 tgtagcgcgc atattctaaa taccctgcat aaattttatt gcgtaagata tctttgactg
     1321 ccgtggtaga aaaagcattc tttttgactg tttgatatcc ttgacgattc aaaaaattgg
     1381 caatcgctcg ataccctgct ccgcctaaat attttgcata gatcagacga acaattttcg
     1441 cctcttctgg ttcaatgacc aattgttttt gaccattcgt gtcaatacca ctgacatagc
     1501 ctaaacgtcg gcctcctgca taacgctttt tatctttcac taagctttgc attgacattt
     1561 gaacattctc cgcaatttgg ttgcgttcaa attcaccgaa actcccaagg agttgtaaca
     1621 tcaatttacc tgtcgaagtg gtcacgtcaa attgttccga gatcgaatgt aatcctacgt
     1681 catatcgcaa taattcctcg actgtttgta agacatctaa catattgcgt ccgagacggg
     1741 tcaatttcca aatcactagt agatcaaaac gatggttccg agcatcgttc atcattcgtt
     1801 gataggcgaa ccgatttttt gtggatttcc cactgattcc ttcatcggca taaacttcta
     1861 ccacttcata gcccatccgt tcggcaaact gtcgtccatt ttgttcttgt gcttgaatac
     1921 tatgtccttc taaagcttgt tcttgtgtac tcacgcgaat atacaatgcg actcgtttgg
     1981 tttgtatcat ttccatagat cattcgttcc tttctaaaat attttgtgtc agttgtcgga
     2041 agtaaatccc acaaactgtt ttatcctttg ttacctcaat ccgacaaaca tagtcacata
     2101 ataattgtcg actagagagg tcttttagtt gaagccattc tttcactttt gcttcacact
     2161 gttggagtga aagaaacgaa gaagtagaca tcggcttttg aagagcttgc agttgttgct
     2221 tgagttcttc cagtgaacaa ttgccctctt caaatgcctt aatccattgt gcttcttgtt
     2281 tcttttgttg gattactttg cgtttttcat cttttcgctt ttcggctaat tgttgcgtta
     2341 attgggcaat caaggcttga tagacgcctt cgtattgaaa aaaagcctgt atcttttcca
     2401 atacttctga ctcaaccctt tctgcccgaa gaaaaattcc ttggcagctt cggtcggtac
     2461 aatgataata atgaagcgtc ttcgtcttct ttgtattcca ttgatacttc gaactcagat
     2521 gacgaccaca gaagggacac cgaatttttt gacgtaataa gtacagatac gtatcttttt
     2581 tagctgtaca ccttgattgg cgaatctctt gggcttgtaa aaaggttgct ttcgagagaa
     2641 tcggttcaaa ggttcctaga tacttcccca aagatcctcc tttgatttcg ccatagtaca
     2701 atggattttt taggatacta taaatatgat agggctgaaa aggacgttcg cggaagaaaa
     2761 gcttttgttg cgtcaatcgt tgacaaagct ttttgtagcc atattttttg gtcaaataaa
     2821 gttgaaaaat atagcgaaca atccttgctt cgtgtacttc ttgttggatt ttcccattca
     2881 ctaaacgata cccatatggt accgcagaag acaaatattg ccgttgttgc tttttatagg
     2941 aaagtccggc acgaacattc tcaataatga cgtttcgttg ttgttctgca aaagtgaaca
     3001 ataattgcac aaatagttta ttcgttgacg cgtgtgagaa agaagcagga agaggttcag
     3061 aaatcgaata cacttgaacc tgatgttgtt ggcacaactc aataaattct aaggctattt
     3121 tggcttgacg tgccaatcga tcataacgcc aaacatagat caccccctct tcttctgacg
     3181 cacaaaccca agctctaagc tgtcgaaaag ctggacgctc cgctttttcc cctgattctc
     3241 ctttgtctga aaatcgttgg ggaatttgtt catatttctc taaaacatac tctttcactg
     3301 catcatattg agcgtcatta ctaattttcg cttcttcata aacagacgtt cgatcataac
     3361 aagccacacg catgcttgat tcccctctct atgaatgaac taaataccat tttttcacga
     3421 ctcttctatt gaacgaacgt tgcacaaagt gattttctaa atatccttcg ttcttcaacg
     3481 cttgaagagt acccccgata gatccagcag atacccctct tatttcgaaa tccaagtaaa
     3541 ttggttttgt aaaaaaggct tgatttgaaa aatgttcttg aatatacaga agaacctctg
     3601 cttttagtgt cattttattt ttagtcatta gaattttcct ttctttcatg tttgattgaa
     3661 tgaagtaaat gaagcataga tcaagcttca tttacttccg tttgggtttg ctcgctatca
     3721 tacagataag taatcagttg ttttgctaaa tcaataagaa atatttccat aacatggtgc
     3781 ctcactttca tactttggtt tattctaaat tacaatcgaa aatacgattt gagtgaagaa
     3841 ggtaatagaa tctcgtatgt tggaagaact tgacgattca tgtgaatacg tttcgttctt
     3901 ctcccttttt ctgcacacat attacccgaa tcaagcaatt gcctaaaaag ataggttaga
     3961 tcctttactt gaaattctcg ccttaacaag tcctcaaacg ggataggaaa aatatttacc
     4021 ttaatatccc catttttttg aattgatact tttccccaaa tcgtactggg cgtatgtttg
     4081 ttgtcactgt ttgttaaaaa tttatggcta ttcatcacca acaatgtttt cactcggtca
     4141 aataccgttt gctcacttcc taaactagta tctacaatta actgttcgta cgaattaata
     4201 agcaccgtct gtatatgctc taatcgtaaa ggatagccca gtatatcttg aattaggagg
     4261 gctccactat aaatcaaagc tagattatta ccaatgcgtt gcttcaaaga atgttcaggt
     4321 aaaacagccc atagtttttt ttgagcttcg acaaaagttg cttcaatttt tgtaatccct
     4381 tgttcaaaga gtttcaaaag aaataacttt ataccccaac caaaagtatt agaagaaaga
     4441 cttttaactt tctctgcgtg attcgcatcc tttgtaaact tgatatcaga aaattcgata
     4501 tatcgaactt tcaaaccagt taatttctca ttgaaataat tttccaaacg ctcttcagaa
     4561 gaggtaaggg tcaaaacaga aaaagtctct tgtggcataa gctgacaatt agaatctaat
     4621 cttagccttt cttctcctga agctaattga tagatcaacg agctaaagtt attttgagtt
     4681 gctgctccta actcatctag tattagtgga acacctccct gattgtttga tgctagcttt
     4741 ataatggctt tattggtagc attcatattt ctaagaaccg tagttggatt tccaaataaa
     4801 gaggcaataa agtgtaacgt agtggtttta cccgttgtgc tcttgccctg taggttaatt
     4861 agtaaactca aaaaagtatt agccttcgta acgtttaaat agcctaacac aatagaagca
     4921 ataccaatcg accaagcaag ttctaagttc gttcctaaaa catacttatg aaccaatgcg
     4981 tcaaattccg cttctgtacc attagttgtt aattggtagc atgagttttt agttaataca
     5041 gaaggaattt cacgtccaaa agaatcttgt aactgaaaaa tcattgcttc attttctttt
     5101 ttccagccaa gagattcatg ttcaaaaaag attggagcat tctcccgttg aatctgtaaa
     5161 aagtcaacga cttcagcttc tcttctagct ttaatgatta agccatgttt tgctaattgt
     5221 ttaaaattat tagtttgtaa acatccacct tctatttcta tttcatccca acaatgatcg
     5281 acataatagg caagaacaag tgtaatgact ttttgttcga tatttttgcg tatttgctta
     5341 ataaacatcg gacaagcaac tttttcttct tgaccttctt tcaccaaaaa tactccttct
     5401 tgattcagtt taaactggtc aaaataatat tcttgattgg attctaatga ttctacagaa
     5461 ggatttacag gttttggcaa cggatatttt tttacaaagt cttgaatatc tttattttta
     5521 tccgaagcat gcagacaatg aaatcgaatc ttattatcag ccgtaacaga caaacaagaa
     5581 ccattagaat tattcgtgtg ttttcttaat ggacattcgt caaatataag taaggtaact
     5641 cctttatgat cgccctcttt tatggtataa gttaattcag gatagtgagc taaccattgt
     5701 ttatagtctg cttgaataaa aggtaacact tctctaaaag atggatggct ttttactcta
     5761 gaggttgaca tcatggaatt ttcttcaact atctgttcaa gaattttaaa acaattactt
     5821 ctatctatgt tatcgggaat agaaaggaaa ctagataaac gatgcggacg ctcttttgtg
     5881 gactttcctt tgaccgctgg tgtaccaact aatttgcata atcttgaagg attataaaca
     5941 gaagtatcaa tatcaacttc atcttctact ccaaatcttc ggtgaagtaa ttgaagaaaa
     6001 ttctgaatag taagaatcgt ctcgtgatta tttggttgtt catttatggg aagaaaaata
     6061 tggtagccat tcccactatc aacttttaca aatgattcta ttctcttttc tttcaaataa
     6121 cgttctactt gttccataac attttctgcc tttttctttt cgctatctgt tgcacttccc
     6181 tctttccttt tagggtcaat atcaataaat acaaaccgaa ttttttcaat atcattgtct
     6241 ctcacagaat gctttttttg tgtaatcacc tcttgtttaa taggattata agttatgttt
     6301 actgtacctt cagacaattt ctgtttttct aaatagttaa taattgcttg agaatctgca
     6361 gtagaaaaaa tatgagaaac ggttttcttg tttaatgtag aaaaagttct caaattaaca
     6421 taagaaatcc ccagtgtatt taacagttgt aaatgcttct gaattgaagt gtgattcatt
     6481 ttcattaatt accactcact ttctaaaaaa tttttatttg tatgactaca ttacctccaa
     6541 cctctcataa tttcatgatc ttcagttcta caaaaatata tcccactcaa aatcttgaca
     6601 aaagaaaaaa gttgtgattt tggaaatcac aacttttttc ttttacgata aatcaatcct
     6661 tattaaatta tttaggaaaa tattgttcaa ttatttcttt atatattttc tcatagtatg
     6721 tttctgtcca tcctaatgtt cctataaaat caagtcctct acattttaaa ggttcactta
     6781 aactattaat atagttaata atgttgtcta tccttttctc tttatcttca ccttcaatct
     6841 ggggagcata tagtccaatt tcctcccaat aatatgaatc tctttcaatt cccatgatgg
     6901 tagctttggc taatttcaaa tcaaataacg attttagaat tcttagtgtc tcaataaagt
     6961 cttctctctt caactcttta atccattgtg aattttctgg attatctaaa atttcaagtt
     7021 catcttcatt ataagtatat ttcaaatttg acttgcttaa ctcatagata aatgaagttt
     7081 cttgactcat aattctttta agtacttgac tataagtttc gtttgacttt gcccatttcg
     7141 ctaattctac cactgtattc actaataaat cgaaataatg atgttctcgt tcaatagtct
     7201 cagcattttg aaaatgaaaa tcacctttat aaactccatt cttttccact gttttattaa
     7261 tattttttaa aaaccagaat gagtttgcaa atttagtcgt actttttcga ttaactaagt
     7321 taataactct tccatgtaat aataagacaa aaatacataa atttttagct tccttattat
     7381 tagatactaa ttgatcaatc atagggagcc attttttgat tttcactaat tgattgctca
     7441 taaatctttc actggacttt tgttcaatct taaattgcaa aacttctaac tcataattcc
     7501 catcttctga tttatttttg ggaacaacta tcaaactttt ataaagttta tccacatcaa
     7561 aatttatctt ttttgcataa tttgtagcca ttaatacatc tccttattca taataaattt
     7621 catatgacgc tcctctcaaa atttaccggt agactagaaa aaagaataaa agatacgtca
     7681 attcacactt tattcttaaa aaaaaactgg tctctctacc ggtaatatcg attgagtccg
     7741 cctttatcga ctttatcctt tttttatatc tgatttgtca aattaagcta gacaatatgt
     7801 ctttatctat gcagctcaaa aatacttcca atggtgttcg ataatttaat gattttcttg
     7861 gaatatggtt tcttttcgag gcaacggatt gaataaaggt ttcatcc
//
LOCUS       DACGLI010000088         7760 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.094, whole genome shotgun sequence.
ACCESSION   DACGLI010000088 DACGLI010000000
VERSION     DACGLI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.094"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="IXT22_002644"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="IXT22_002644"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAQ4863961.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="IXT22_002645"
     CDS             complement(2032..3273)
                     /locus_tag="IXT22_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4863962.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="IXT22_002646"
     CDS             complement(3291..4214)
                     /locus_tag="IXT22_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4863963.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="IXT22_002647"
     CDS             complement(4435..6927)
                     /locus_tag="IXT22_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4863964.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="IXT22_002648"
     CDS             complement(6934..7401)
                     /locus_tag="IXT22_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAQ4863965.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="IXT22_002649"
     tRNA            complement(7537..7610)
                     /locus_tag="IXT22_002649"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="IXT22_002650"
     tRNA            complement(7668..7741)
                     /locus_tag="IXT22_002650"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2162 a         1691 c         1246 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acaaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DACGLI010000089         7682 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.095, whole genome shotgun sequence.
ACCESSION   DACGLI010000089 DACGLI010000000
VERSION     DACGLI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.095"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..202)
                     /locus_tag="IXT22_002651"
     CDS             complement(<1..202)
                     /locus_tag="IXT22_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863966.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHN"
     gene            complement(195..632)
                     /locus_tag="IXT22_002652"
     CDS             complement(195..632)
                     /locus_tag="IXT22_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863967.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(647..898)
                     /locus_tag="IXT22_002653"
     CDS             complement(647..898)
                     /locus_tag="IXT22_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863968.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(898..1104)
                     /locus_tag="IXT22_002654"
     CDS             complement(898..1104)
                     /locus_tag="IXT22_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4863969.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(1541..1801)
                     /locus_tag="IXT22_002655"
     CDS             complement(1541..1801)
                     /locus_tag="IXT22_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863970.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            1876..2079
                     /locus_tag="IXT22_002656"
     CDS             1876..2079
                     /locus_tag="IXT22_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAQ4863971.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(2220..2705)
                     /gene="ssb"
                     /locus_tag="IXT22_002657"
     CDS             complement(2220..2705)
                     /gene="ssb"
                     /locus_tag="IXT22_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4863972.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(2708..3607)
                     /locus_tag="IXT22_002658"
     CDS             complement(2708..3607)
                     /locus_tag="IXT22_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4863973.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(3620..4213)
                     /locus_tag="IXT22_002659"
     CDS             complement(3620..4213)
                     /locus_tag="IXT22_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAQ4863974.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(4454..6658)
                     /gene="topB"
                     /locus_tag="IXT22_002660"
     CDS             complement(4454..6658)
                     /gene="topB"
                     /locus_tag="IXT22_002660"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4863975.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(6669..>7682)
                     /locus_tag="IXT22_002661"
     CDS             complement(6669..>7682)
                     /locus_tag="IXT22_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4863976.1"
                     /translation="ELKPKYERQNFLVRDDRLDHAVAFLWKDPQTKETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKIIYEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVS
                     AHKVNAFFGQQLSVNDSIEAINLKDICREVAKELKVCERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFIPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT         1939 a         1574 c         1332 g         2837 t
ORIGIN      
        1 gattatggct gactgtaacc ttcgtttgac tcgtttcact ttccatatac aactgttctt
       61 ccactctttg aataaagtac ttcatttctt ccatacaact aaagtctttt tgaatccgtc
      121 tgattacttc attcaagtgt tctttgtttg ttaaaaattg cgaaacatct tctgttgtta
      181 gctgataaac caccttattc attatctttc tcctccgatt caatcgtata aaatgcacca
      241 tttttttcga tattttcaaa agtatctagc cagtcgctag ccattgcttt agctttctta
      301 atctgtgcga attttgcata agtcagttct aaggcttgat attcggaagg tttgatagtg
      361 cttggtttga cacctacttc caagcatagt aaggcttgga aaaaccattt tccattttgt
      421 tttttcagtt cttccagtgt tcgatagtac gtcgcaatga gattcatttc gacacctgat
      481 tcaatcattt cttccactgc gactgacaat ttttccttgt aatgtttttt gggtacacgt
      541 gtttcatggt ataggaacgt catatcctcc attttttgtg ccattttatc caaaggtaat
      601 ttgacaaatt cgtcatagta attttgagcc atattttttc tcctttttag ttctctaatt
      661 tggttaacca atattcgatt tcataagttt ccatgttttc ttgataatgc agttcatatc
      721 ctgcaatctt cactaggtct tcaaatagca tagtcggtgc atcctctact aaaggggttt
      781 ctatcgtcca gtaccgcgga ataagtaaag cttctgctac tttttcagaa atgacttctt
      841 tgtccaccaa aatttgaacg acttctttta cagtcaataa tttgtgttgt gttttcatca
      901 ccgtttcttt actttctcat caatcaaaac ataatcgcca taagacaagg tatatttttt
      961 cccgcatgtt ggacattgat acaaacgata gcttttgata catttcgctc tttctccaca
     1021 atcgcattcg acagtatgtg gtgcatgata gtttgggaat aattcgctga agggaacacc
     1081 ccaataatca aatttctttc gcatgattga ttctgcctcc tcttaggaaa ggttttattt
     1141 cctttcgtta gttctttctt tattgatttg ttggccagaa tgaatcaacg aaaagcgaca
     1201 aggacaaggg cgcgcagcgt gccatttacc cttgtccttg tcgctttttg gtgataaaag
     1261 gcaacttgtt gccggtctgg caaatcaata aagagatagc gaacaggaac gaaccttttg
     1321 gtgagaggaa gttttttcta ttttgtcttg ctttgcaaga caccatatct tagtgaacgt
     1381 gcaacgttca cttcctttct tctcgaacgg cggtggcggt tggagtgaga gaaaggtttt
     1441 tcaattgaga aggcacttgt gtcttcctaa aaaggtcttt tcctgtttct atgtaaaaca
     1501 aaaagagctg caatcctcat ttaggactgc agctcttctt ttatatgccc atcgatcgcg
     1561 taaaatgatc ggggtttcta atttgcatcg attcaatgac taattgattc cgtttattga
     1621 aatgacctgt gacggcaata ttgtattttc catcatccat aattaacaat ttatcgataa
     1681 tttcaatatc tgcaactaca caattaatcg attcatgaat tgtttgtaaa gtaaagcgaa
     1741 ccaataatgg ttgtgttttt attactcgga ttttatcaag caaaccaaca tatttgttca
     1801 tcacgatcac ctcgctaaaa ttatagcaaa aacagctaaa attgagaatt tttattcgat
     1861 tttagatatg ctataatgat caagacagta aagtttgtga cggtggctat ccgattgaaa
     1921 gtgaggtggt gcgtatgtgc gtacttccaa aatcttacag aaaggagaag ccttttgcct
     1981 gttgaaacgg cgctaggatt aatgattagt ttcggttctt tgatcgcaac aatcattttt
     2041 ggaatcttag cagttgtaaa caacaatcaa aaaaaataac cgtcagcttt agccggtcga
     2101 cgattatttt tcaaaaataa tattaagctg gtcaccgtct taaacggtgc tgttagggga
     2161 gttgttagcg caactcctct tttcgtatcc attataacaa ctttattgat cttttacaat
     2221 cagaatggta aatcatcatc actaatatcg attgattgtc cgccaaatgg attttgtgaa
     2281 gcgttcaatc cattgttgtt aggcgtagct acatcccgtt gttcaaaggt ggtagggctt
     2341 ggactgctgg acgattgatc agcgtgcgca cggctttctg tcgctgcttt actttctaat
     2401 agttggaaat tatcggccac aacttctgtc acatacacac gttgtccttg ttggttatcg
     2461 taggttcggg tttgaatccg tccaacaacg ccgatcaaac tgcccttttt agctaatgtc
     2521 gccatcgttt ctgctggttt gcgccaaatc acacagttaa taaaatcagc ttctcgattg
     2581 ccgttttgat tcgtgaaatt tcggttgaca gctagggtaa aagtcgctac tgcagtacca
     2641 ctcgcggtat aacgtaaatc tggatctttg gttaagcgtc ctactaaagt tacattattg
     2701 atcatcttta tctctccatt tcttgattca tttgttgtga tcttttaaac tgccgttttc
     2761 tttcttgatt ttcaattttg atcacacttt tcattaggtg atcaatttcg ttgactgtat
     2821 ctgtaaatga aatggaattc gcaaacgtgt taactgagcg atatttttcc cactgctttt
     2881 ccaaatagtc atttcctctg atcttatcca tttctctttc ataataaaag gacaacggtt
     2941 ttgtatcccc acgttttgta aatgtatttc gaacactttt gtataactct ttcgtatcga
     3001 tattttctag tttcggaatg gtaaataagt cgtagtaatc ttttgctctc gaattatctg
     3061 tgccaaagct gaacgtagca cttagctttt ctgcaataat ttgttctgtt ggataagctg
     3121 gaatctccac ttttttatct tcaaacatta attggtgata gtgtgtatct acttcaggat
     3181 aaatagaatc tcctgttgtc acgtccattt taaacggtac acgtactttc tctaaattag
     3241 ccaccaattt aatttgaaat ccaggataaa aatcggcttc tcttgtttcc ttcattcctt
     3301 gaatagagaa aacaatgcct tcttttgtgg gttttctagt taaatcatta aaaatgctct
     3361 tcaatttttc ttcagttaat ttgctatttc taaatgtcgt atcgatatca attgttgtcc
     3421 ttctatcgat tccatatttt gatcctaata aaaagccgcc tttcaaaatg aagtcatttt
     3481 tgtactttga ttcagaaatt tgttcaatta gacgatccat cataaaatgc cgttgcacta
     3541 actgtgcatt taatcctgta ctctttgcta aatttcttgt ttttgctgca aattgtgtcg
     3601 gtgtcatctt tttcctccat caatataagc tttgcatgtg gtatttcatt tctttttcta
     3661 catgtagttt tgtcatgtaa tctcttaatt tacttggatc tctcaatggg tcttccatgt
     3721 actcttttaa tgcttctaat ttcatttcat attcaaattc atatctcgga ttccaaatat
     3781 cacaaagtgt acgctcttta tcatacatag taataggatt tccttgaaag gaagttccct
     3841 ctacttttcc tagttcataa acttctttct tcacgaaatg aaattgtaac tgctgctctt
     3901 ttgtaattga acgatcaacg ttatagccat ggggaaaagt taagtgaatg aatttcggca
     3961 tattcgtaga aagctggtaa atatctaaag tcgtttcatg agagaagatt cccctggaaa
     4021 atcgttgctg aagccaaaat aaatcatcta ttccatgacc atcctctaca taataaccac
     4081 gatcaacttt gatcaatttt ccttgattca ccaatctttg tacagtggtt gctgcgattc
     4141 caaatttcct ggcttccttc atagataaat ttccatcgcg aatagccaac aattctttca
     4201 gtttatcttg catttacttc ccctcccttc gttacaaata cactacatca aatatatcat
     4261 agtagtttat ttgtaacaag attaacgtct atcgatctaa ttcgatttct ttttgaatgc
     4321 gctgctggtt ctttaattgt tgcagtcttc ttttatttgc acgtaatttc tcttgttcta
     4381 aacgaatttt tgctttttga ttttcgattt cttgttgttt gtgtgttgta tttcgcatag
     4441 gataacccct tcattatttt gtagtgcggc gtgttctttt cttatagttc gtttttttct
     4501 tttcagaaaa ttcaaagcct gttgtaaagt cttcttttaa aacgatcgtt gcttcaaacg
     4561 aacctttctg accttttagt cctctgactg attggcttgt tcggccgttt tgaatgatct
     4621 ctttcagttg tgtggctgtg agtttctttt tggcaatcgt tgtccataat ttaaaatcac
     4681 aggcttcaga cgtacatgcc gccacatttt gataaagcaa gacttcttgt tcccgacatt
     4741 ttggacaaac acctaaatga cgcgttgctt cctgtttttc actggctgct ttcacttctt
     4801 gtaacgtcga tccaaaatca gtggattgga tttgccctgg tacgacttcc aataagtgag
     4861 agacaaattt ttggatattg gctagaaaag tggtttgtgt tccttttcgt tcaccgatct
     4921 ttaacaagta gctttcccat ttggcggtca tttcggcact cgtaagcagc ggctcttttt
     4981 ccacggcttg gcaaagcaaa atccctttat tcgtcaccac gagcttattt ttctctacct
     5041 tgatatattc cttttgtttc aaggtttcaa taatattcgc ccgtgtcgct tctgtaccga
     5101 ttccttccac ttctttcaat atggattgcg cttcttcact atcaacggtt ttcccagctg
     5161 ttttcatcgc cgtgatcaac gtaccttcgg tataaggctg tggtggcttg gtttcttttt
     5221 caaggacttg tagatctacc gtcaccattt ctccttttgt cactttagga agtagcggct
     5281 cttcttcctt ctcttttccg tcgttctctt tgccaaataa cttcttccaa cctagatcta
     5341 tcggtacttt tccgattgcc tttaactgaa gctgctggac ttgcgtcaag atcgttgttt
     5401 cttcataggt atatttttcc gcaaacatgg ccaccgttgt ttttaacact tgttcataaa
     5461 tggcctgctg cagtggactt agttgttcaa aagccgctgc tgtcataacc gtttttgtag
     5521 gaatgatcgc gtaatgttcc tggactttct tgttattcac ataccgacta ttcggcgtat
     5581 gaataggggt tgggattgat tcggccttta aaaaatgctt gtattcatct aaatgatcca
     5641 acaaatacgc atactcccct tccgtaatat aaggggtgtc tgttcgtgga tagcttagat
     5701 atttcccttc atacaagcct tgcatggctt ccaaagtgtc tttggcacta gctttcatga
     5761 gctgattcat tttagactga aggctggata gagaaaaaag acgtggactt gccgcgcttt
     5821 ttttctcggt ttcaacttgg cgaatcatgc ctggctgttt tcccaattga accccctttt
     5881 cttttaaata atcttcaaat gcttcttgcg tcgcttgggt ttcattcgga tcaagcttcg
     5941 catcaaatgc gccattttga gcgattactt cggattttcc ttcaaaataa ggttctttct
     6001 tgaaatttct aatcttttcc tgcaattgat aaatcatgta aagcgttggg gtttggactc
     6061 tgcctaagga aaagcttcct ggtatgcctt tttgctgcaa gagtaaacta tacagtgggc
     6121 taccgttcat cccaattaac caatcggcga tctgacgtgc ttgtgcttct tcaaattttg
     6181 gataggtctc ttttgcgtct cgtaactgct ggaatccctg ataaatggct tctttttcta
     6241 aggagttgat ccaaagtctt ttaaaggttt ttccttgatc ggcgcctact tgttgaatga
     6301 tcgtccaagc gatcagttcc ccttcacgat cgctatctgt cgcaataata atggtgtcgg
     6361 ccgattgaag ttgctgtttc accaccttga attgcttttt cttatcttta ggaacatgat
     6421 agtgataatg tgtagggaaa ataggcaaat gttctaatga ccattgtttc caattttcat
     6481 cgtacatatc gggcgaatct aattcgacta aatgaccaaa accatacgtg atcacagttt
     6541 caccaggaaa caatcgatct tggatttcaa aatacccgtc ttttcgagtg gctttagaga
     6601 agctatcggc ataagctttc gcttgtgacg gcttttctgc taaaataacg gttttcatca
     6661 tgacgatttc actccctttc ttgttgtctg ccttgttgaa acaacatggc acgtttttgc
     6721 tttctgattt cttgttgctg gatctcatgc ttcaattgat cgttccagtc cttttttact
     6781 tcaggtataa attcatgttc atgattttta tagcctttgt agtattgttc tgctttataa
     6841 gagaaaagaa tctgcgcatt aatatcccct ttttcttgat aaaaacgatc aaaatcgtac
     6901 gtaccatcca cgcgttcaca aacttttaat tcttttgcga cttctctaca aatatctttc
     6961 aaattaatgg cttctattga atcgttaaca gaaagctgct ggccaaaaaa cgcatttact
     7021 ttgtgagcgg aaaccagttg gttcgttaat tgcagattgt tttctgtctt gtgtatggcc
     7081 ataatagctt ctggtgtgac cttttcttct tttgcgactt cttcataaat gattttgtat
     7141 tcttttggca cttgccaatc attagcgatt cctcgttcac aacgtacttt ctgattcgta
     7201 aatggatcga ctgcgcccat taattgttct ttttcgtaga aaatatgtcc tgcacggtca
     7261 ttatccacac aaatctcgat ggattgagga aaggcttgtt tctttctcaa ttcagatact
     7321 gcctcaccaa aataatgact gatcacatgg tgttttaacc cttccataga gactaaccac
     7381 gtatcgttta actgatcacg attcagtgca gcatagctaa gtaaatcaat actactctca
     7441 aaaaatttta actgcttagg gtcaccgatc tttaggttaa agccatgatt cgctgtcgaa
     7501 tttttatcta tatgcttata tgtgcctctc tcaccaaaac gttcataatc aatgaacgtt
     7561 ccttgataac tcgcccctac tgtctctttt gtctgtggat ctttccataa aaaggcgacc
     7621 gcatgatcta aacgatcgtc tcgaactaag aaattttgcc gttcatattt tggctttagt
     7681 tc
//
LOCUS       DACGLI010000090         7600 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.096, whole genome shotgun sequence.
ACCESSION   DACGLI010000090 DACGLI010000000
VERSION     DACGLI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.096"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(138..428)
                     /locus_tag="IXT22_002662"
     CDS             complement(138..428)
                     /locus_tag="IXT22_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863977.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="IXT22_002663"
     CDS             complement(546..806)
                     /locus_tag="IXT22_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863978.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="IXT22_002664"
     CDS             complement(943..1356)
                     /locus_tag="IXT22_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAQ4863979.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="IXT22_002665"
     CDS             complement(1812..2297)
                     /locus_tag="IXT22_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863980.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="IXT22_002666"
     CDS             complement(2436..2651)
                     /locus_tag="IXT22_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAQ4863981.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="IXT22_002667"
     CDS             2875..3675
                     /locus_tag="IXT22_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4863982.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="IXT22_002668"
     CDS             3694..5562
                     /locus_tag="IXT22_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4863983.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="IXT22_002669"
     CDS             5555..6046
                     /locus_tag="IXT22_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAQ4863984.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="IXT22_002670"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="IXT22_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAQ4863985.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="IXT22_002671"
     CDS             6606..>7600
                     /locus_tag="IXT22_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAQ4863986.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DACGLI010000091         7352 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.097, whole genome shotgun sequence.
ACCESSION   DACGLI010000091 DACGLI010000000
VERSION     DACGLI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.097"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..448)
                     /locus_tag="IXT22_002672"
     CDS             complement(<1..448)
                     /locus_tag="IXT22_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4863987.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
     gene            complement(755..1852)
                     /locus_tag="IXT22_002673"
     CDS             complement(755..1852)
                     /locus_tag="IXT22_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4863988.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            complement(1960..3987)
                     /locus_tag="IXT22_002674"
     CDS             complement(1960..3987)
                     /locus_tag="IXT22_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAQ4863989.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            complement(4132..4863)
                     /locus_tag="IXT22_002675"
     CDS             complement(4132..4863)
                     /locus_tag="IXT22_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4863990.1"
                     /translation="MMKKEIVLTAAIMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            complement(5379..6278)
                     /locus_tag="IXT22_002676"
     CDS             complement(5379..6278)
                     /locus_tag="IXT22_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAQ4863991.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(6288..6644)
                     /locus_tag="IXT22_002677"
     CDS             complement(6288..6644)
                     /locus_tag="IXT22_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4863992.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            6999..7295
                     /locus_tag="IXT22_002678"
     CDS             6999..7295
                     /locus_tag="IXT22_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAQ4863993.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
BASE COUNT         2153 a         1463 c         1181 g         2555 t
ORIGIN      
        1 tcaactttct cttttcaaaa aaaatttgat atttttttag atttcttttt agtctttgta
       61 atactttata agccacagaa taactcacgt gatgctgttt agcaaaattt tctactgaga
      121 tatatttttc ctgaaagaaa gccaatacca ttttcataga taaagaatcc gttatataac
      181 gagataacag agctttgcta gaacattttc cattaatttc cagacatata tccaattcac
      241 tgacggttac tcgcaaattt ttctctagat cgaacttttg taaatcatgt ttcagcttat
      301 cgatcgtttt tttcaagaga aatgtcgata gcgacaactc ttcttgaaca ttcgatattg
      361 actctgataa atttgagctt gcttctaaat atttaagtaa tgaataactt ctgtgatctt
      421 ctttgcttaa aaaaaactca taattcatta gtcatcagct ctttctacgt atattacttt
      481 ccatgcattc accaactagc tggggataaa actgatttcc tggatccgag tcactgttgt
      541 cagcgattct tgtttgtata atatacatcg tcctgtcttt tttttaacat tttggagagc
      601 gttttatttg gcctttctcg cgatcaaacc tgttattaga attatatcat ttactagtat
      661 gcatttttat taataaaatg gtatatttta tattgttata aaaagagccc aaccatccta
      721 caataataaa aatttactat ttgttatctt aaccttactt ttctttctct tctttttttc
      781 tcaaaacaaa caaaagtatg cataataaaa taaacaataa gaaaagtgaa gctactaaga
      841 tataaatcca attattgtct tttttaatcg taacatccgt cgtgttcaat tccttggcta
      901 cttttccgtc tattgtaaaa tctttttcaa atacccattg attggtatag ttgatcgtag
      961 tatttccttt ttttctcgaa aattttccat tttcattttc atttcctaaa acagtcattg
     1021 taaggtgata ttcacctggg gttagcggtt gaccatttaa agcagttgga aaagaaaaat
     1081 ttgtattcgg cgcaatctgc aatccttctt tttcctcttg atataaaact tcagaatgtc
     1141 ctttttttgt aatttttgtt tcaataacta cttgattgat ataggttttt tgatcatttt
     1201 gaacgtttgc taagatgaca tttcttgcat tgatttgatc tggtttaact tcatgaagag
     1261 taaggttcgg agcaacttcg ttcagtgtct gttgcatcaa caaagcaata atataggtgt
     1321 attcattctc aatcgataag ctttgatcct tagtttctgt ttggtccttt tccgtctgga
     1381 tttcttggaa tgtgatccca ccagccaata caccatcaaa tcgctcattc ggcatcctga
     1441 catgaaaagc aacggtttgg acacttttag gttttagcgt cactatctgt ggatagctca
     1501 cataatctac cagatcaaag atcaggctca tgtctttttc aatctcgttt tttccgtatt
     1561 caaccatcac atttgaattg gtggttgcgc tattcacaga aatatcgatt ttcacttctt
     1621 tttctgtatc atttctcaat tccgctttta cttctacttc ctgatccgga tcaagttgaa
     1681 gatcgaagta agtttttctc ttgtcgattt gattctctga agttatcggc gtcactgaaa
     1741 aattaaatgc actagctgac actgatatat tgttaaaaag tgcccctaaa ataactagga
     1801 gtgttataaa taattgttgt tttggtctca agaaaatcgc tcctttaatc atatgtaaga
     1861 gaagactata acaaaatctt gtctctgtgg gacacaagag cctatggtac ctgtgccctt
     1921 cttgaaactc aataattttg ttatattctt ctcttcctgt taatttcctg ggacatctgc
     1981 aagtatccaa gatagtttcc cctcaaaggt tccgattctt tggttttcta caggaatatc
     2041 tattctgatt ccacgatgag ctgtagaatc taaaagagag gacaaatcgc tttcaccctt
     2101 ttgatcactt tcgaaaatcg taacagcgga tgtccctata accgttgtat tttcagaggt
     2161 aacaaaggaa agagcttctg gaagctcaaa atctccattt gtaagaactt tctcttgttt
     2221 caattgtaat ttccaacttc caaaagcccg ttcatctata attttcaacc cacctgaaaa
     2281 ctgtccgaat tcacttaatg gtctactgga tattttatgt tttccaaaat tgacatattg
     2341 aggagcagtt gagagataaa gtttgccttt tctgtaataa aaatagatat cctctgtatt
     2401 ttcggagaag atgccttctg tattcgctga atccgagtca aaaacatacc cttcaatatc
     2461 aataggagtt tctttatact tctctcctat tttcccagtg attgttttca tttcagcaat
     2521 atcaatctga ctgtctttat ctttataata aacatggata tctatctcct tcagctttgc
     2581 gatctttagg tttatttcat tcgattgctc aatcaaattc ccgttttcaa ggtattcaaa
     2641 atgcatagtg agtacttttt caggaattac ttcctgcaaa gttgtctcca attcgattat
     2701 taacgtatct ccagcaataa aataatctgt cagatttagc gtgactcgat ttccggttat
     2761 caagatatct ttggcatcaa tttgatttcc attgatcaag atatgctcgg gaatagttaa
     2821 ttcttgtggg aggtcgatac tagtctgcat tttcttatat tcaagaaaat ccccctcgac
     2881 cttcaatgta tttctgatag ttatcttatc gtttcctcca gcttcagcga tggccccata
     2941 atcactatcg ttgactttta catcagctgt tgatgtgaca ttcgatggaa gtcgcgtgac
     3001 agcgacagca ttttcttgaa aaaaagtacc tgttgaagaa gtaaaccccc aatttacttc
     3061 tgtagaacca aactgcctaa tgagatcagg tataatccga gaagagcgac cgacaccttc
     3121 caaatcataa gtaagacttc tttgctccgc gtcccattta attattaaca agcgccatgt
     3181 gccattagaa agaaatgtag gagctaccgt cacgccagta tgctctccag aataattatt
     3241 attatttggt ttaggcgtga caaaagcgac atgtccatgc cctctattat cagcagttat
     3301 ctctcgatcc attcgatcag aagaaccact atttttatac gtatcaaact caatcgagag
     3361 cgcattcgca atgtaaggtt ggccagaacg agtagaatat gagccaattc ccatacctgg
     3421 cgatccaata acttgactgg gattactagc cattctagga tcgccagtca atgtaaaggt
     3481 catgccatct cccgctctat ctcgttgatt tcctaagtat aaataagatt taaatgtaaa
     3541 atccgagagt aaactaatct tcttatttga ccaaatagct cctctttgag acctttctgc
     3601 tgggttcaac tgcagtaact tcccattttc caatatggac gtgctagtac cgataggtgt
     3661 ttgaaaaatt ttatcgatag aaataatatt gggatcgtca ggcagctcaa ccgcagaaat
     3721 tggtgcatct tctagtcctt gtttgtccga accctcagct tctacgttgt cagtggtctc
     3781 tccactactc gaaatactta aatcctcact gctttcttgt gtctggttgg attctattaa
     3841 actgtcgaat gtcgaagtga gtttgctttc ttcgtctctt ctatttccat gctccaactg
     3901 attcaattcc aaagagtacc ctatgatcgg aaagatatta gtcactaaga gactgcttaa
     3961 aatgagcacg atcctcctct ttttcaatat atcttttcct cctgatcgtt aaattcctag
     4021 atgaactatt cgtatccaaa caaatttagc ctagcctttg acaatttttg ctcgattacc
     4081 tcgcaagaca atatgactac gtatttattt ttaacagttc ttttcagtaa actagttgtt
     4141 aggtgtatct tctaatgtcc aaactaattt agtggaatat tgttgcgcta acttgacaga
     4201 tttaccgggt accgaaagct gtaccgcatc ttgattttca ttttcatttg caccaaatcg
     4261 atagacccaa gtccccacac ctgttcctga tttagcatta attgctaacg tattgtttcc
     4321 tcccggtgtc aacgttaatt cagaattcac cgtttgcggc gtatatgttg gatcaaccaa
     4381 agaaacagcc tgccctttcg taaatttcag ctgtgctcca actagttcat ccccactggc
     4441 agttttaaac tgttctggtt gagagacact taatttccac ccagataagg tacttctcct
     4501 atctgtcact tggacatatg tcggttttct agacccatcg ttcatcacat cagcagctgc
     4561 ataatacgtt ttatccgcag tagaaatttt ttgagtccca aatttgaatt ttgatccata
     4621 atcaatcgat aatgcccctc ctgttccagg gcttggagga tctgatggat cgacaggttt
     4681 attgggatca ggattctctg gatcaacagg aggagttaca ccctcatctc ctgcttcaaa
     4741 tgtaatcgtt ccttctgtgt tatattcctt tgggtatact tcagttgcag aaacaaaagt
     4801 cgtacttgct accatgctga ataacattat tgctgctgtt aatacgattt cttttttcat
     4861 cattgacatt cctctttctt tatttactaa acatatcagt cgattggatt aatccatagc
     4921 aaaattctgt tttacgatac ttatgaaata aaagaacata gacctatatt tggtcctatg
     4981 tatcgattag ttataaatga ttatcagccc gatttgattt ctagttttta ttgcaacttg
     5041 atgcaaacac aatctagaaa tacagctgtc atagccttta aaataattcg taagtccccc
     5101 tcctatctat caaaatgtga cttgactgcc tagacttcaa tcaatattaa ttataattaa
     5161 ataaaaaatg tatattatat tttttttgtg attatcgttc aaaaaaagaa tacacgcttg
     5221 catctagtac tctgcgagtt acaaatcatc cgatcaaata aacattcgct gattattttc
     5281 cgcaaaaaaa gcagcatatc cacgataaat ggatctactg ctcttactta tccttatgtt
     5341 ttacaaggta ttttctttta cacattacta atgctgtctc aatacggaac gattgtcatc
     5401 gcttgttcaa attcctcttg caaatgttgt gtttgatagg cctgaaaagc tgggtgatgg
     5461 gcacgcaaga ggacacgtaa tttcatagga tcatagctgt ctagcaactg ttctttcaag
     5521 acaaaatctc gggtcagctg ccattcataa taataaccaa aaggtctgca gctgtaaatc
     5581 gtgtgaccga tggatttatc ttcaaagcga cgatgcgtat ggccaaaaac tacttgtttg
     5641 atatttgaat aacggtcaag taattctccg aatgattctg atcctaaaaa tgcatttaat
     5701 ttgttccaac gctcataagg agcagattga tacatgataa atgcccgttt aggaacgaaa
     5761 tgagtggata aaatcacctc aagttttttt gcttccagct ggtctagcaa attttttgca
     5821 gctgcaagca tttctgcatt gacctcgaga tctgttttcc cacgctggat gaaccgatca
     5881 taccaataca aacgcttcat tcgtacgatt gcctcgtaat ctttcaattc ggaaaactga
     5941 tagtcgtacc agccattcat ccctaaaaga acggtctgct catttaaagc aatataccgt
     6001 tcatttaaaa aatgtgggtc tggaaaatgg tccatcatct gttcattggg cacatctgcc
     6061 aactcgtgat tgccgaaatg aaatgtcgta gataatcctt tattgacgaa aaattcgaca
     6121 acagctaggc aacggtctac tttattagcc gtatctccgg ctagatgaag ccgagtgatc
     6181 ttgtgctttt gcaaaacttg ccaaagctgc atcagctctg attcgccgaa tttattgatg
     6241 tccacatgta ggtcgctgat gatcgccaat tttcccattt tatccctcta gtcttttcga
     6301 acaacttgca agttgccttt tctcaagccg cttggtcctt ttaattgtaa actattataa
     6361 gttggttcta aagcaagtgt ggatggatca tccatgtaaa gtattgcact gtctttgatt
     6421 ttgattggtc caactggtgt atcagccact acagaataaa gacttagatc tgtttgtgta
     6481 tcttttttga caatgatcaa tcgaaatgcc gtatccaatt ggcaactgac ttggctttct
     6541 gcaaatggac cgtcaccgtt ttcgatatct aataaaagtt gatcgtctgc ttctaattta
     6601 ttcttcaata cttcttgtgc ttcttttgtc acttctaatt tcatctgtat cacctcatgt
     6661 catagaataa tcactttatt catcagatgc aactaatttg tctggttctg actgttctca
     6721 atttattgga aagtaagtca ttcgtttatt atgatttctc ttatcacaaa agagacaact
     6781 ttcccttttc ttcgttcagt ttcttgaacg gaaaaagacc caaaaagcaa cctgttattt
     6841 gtttaacctt attcctttct taaataacaa aaaatactat aaaaaataaa aaacctttaa
     6901 caactattgg aaaaagaatt actttttgtt cacggattat taacaactct tcggtagagt
     6961 aaacttatca aataaaagac ttctttggag gaatcactat gaaggaatat ataaaaaaca
     7021 tctattttat cgaagaaaca caaaatatcg agggttctta tattgaagta aaaacactct
     7081 ttgtcaatga agataaaacc aaagcattgg atatttataa aaaattagct tcaaaaaaaa
     7141 cgaatagttt tggattgata ttaagcgagt ataaaatcaa agcagaagag agttatttct
     7201 atcaattatt aaaacggtgg agtaagcttc ccgccgattt ttatcgaaaa atgcagatca
     7261 tcaactatca accgcttgct gagacacatg cctaaataga ggttgtgaaa tcagtgcttt
     7321 gagctaatac cgaaggtcag ctgattgaac at
//
LOCUS       DACGLI010000092         6694 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.098, whole genome shotgun sequence.
ACCESSION   DACGLI010000092 DACGLI010000000
VERSION     DACGLI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.098"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            302..898
                     /locus_tag="IXT22_002679"
     CDS             302..898
                     /locus_tag="IXT22_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4863994.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(956..1438)
                     /locus_tag="IXT22_002680"
     CDS             complement(956..1438)
                     /locus_tag="IXT22_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863995.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1544..1741)
                     /locus_tag="IXT22_002681"
     CDS             complement(1544..1741)
                     /locus_tag="IXT22_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863996.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2036..2794
                     /locus_tag="IXT22_002682"
     CDS             2036..2794
                     /locus_tag="IXT22_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAQ4863997.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2854..3282
                     /locus_tag="IXT22_002683"
     CDS             2854..3282
                     /locus_tag="IXT22_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4863998.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3328..3400
                     /locus_tag="IXT22_002684"
     tRNA            3328..3400
                     /locus_tag="IXT22_002684"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3361..3363,aa:Gln,seq:ctg)
     gene            complement(3550..3921)
                     /locus_tag="IXT22_002685"
     CDS             complement(3550..3921)
                     /locus_tag="IXT22_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4863999.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4136..4321
                     /locus_tag="IXT22_002686"
     CDS             4136..4321
                     /locus_tag="IXT22_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864000.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4404..4592)
                     /locus_tag="IXT22_002687"
     CDS             complement(4404..4592)
                     /locus_tag="IXT22_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864001.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4616..4879)
                     /locus_tag="IXT22_002688"
     CDS             complement(4616..4879)
                     /locus_tag="IXT22_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864002.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5037..5294
                     /locus_tag="IXT22_002689"
     CDS             5037..5294
                     /locus_tag="IXT22_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAQ4864003.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(5365..5556)
                     /locus_tag="IXT22_002690"
     CDS             complement(5365..5556)
                     /locus_tag="IXT22_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864004.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(5697..6017)
                     /locus_tag="IXT22_002691"
     CDS             complement(5697..6017)
                     /locus_tag="IXT22_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864005.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(6040..6474)
                     /locus_tag="IXT22_002692"
     CDS             complement(6040..6474)
                     /locus_tag="IXT22_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4864006.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2100 a         1303 c         1022 g         2269 t
ORIGIN      
        1 taaactaatt ttctataaaa gcaagtaatt tttaatggca atatcataaa aaaaagaaga
       61 tagagattta ataattatat atcagctgtt tttttcaaat aagcaaaaat tcctaaaaca
      121 caacaatgaa agcgataact aagaaaatcc ttacataacg atttttctta ttaaaattgt
      181 tttttgaact tcgcttattt tttgtgagca tatctgttta cttacttttt gtaaggtgct
      241 atacttcatt tcgtaatcaa ttaaaaaaat gcaaaacgca aatcaaagga gaaattttat
      301 tatgacaact tttactgaca ctttgaaaaa ccgccgttca atctatcatc taggacgtaa
      361 tgtttcactt tctaatgaag aattaacaac tttgatcaaa gaagcaatta aagaaagccc
      421 aactgctttc aatgctcaat caacacgcgc agttatcctt ttcggagatg cacatgaaaa
      481 actttgggaa atcactgaag aagcacttcg cccattgact ccagcagaag ctttcccaaa
      541 tacacaaaac aaattagctg gtttcaaaaa tggttatggt acagtattat tcttcaaaga
      601 tactgacgtg gtaaaaggtc tacaagaaca atttgaatta tatgcagaca acttcccaga
      661 ttggtcagaa caatcaaacg gaatcgcaac agctaatact tgggtagcat tagttgataa
      721 aggattgggc gcaaacttgc aacattacaa cccagttatt gacgaagcag ttgcaaaaga
      781 atggaatatc ccttcaaact ggaaactacg ttcgcaatta gtattcggtt caccagaaac
      841 accggctggg gaaaaagaat acatgaacga tgccgatcgc ttccgcgtat ttggataatt
      901 ttatttgaaa taaaaaacag aggttgtgac aaacatcttg tcgcaacctc tgtttttatt
      961 ctggatcaat cataatatca atctctgcct catcgtttaa gcgttgggac aaaaatggaa
     1021 ctaattcttc taatgatgca gaaaatttca gcatcggtcc tcgccatccg tttcggaaaa
     1081 aattcatttt tacgatttta gaaccttttg gctgatataa tacaatttta ttgatctcag
     1141 aaaaaggaac accttttttg tcaaagctat tcaaaacaag tccttcttct gtgattcctc
     1201 tactgtccaa caaaaaacta ataaaaatca ttgctgacaa gatccctttt gccaattcat
     1261 ctgctgtagg atgactgatg agtgtatacc aaatgactag tgacactaag aagggtatca
     1321 ccaagtagac ccatcgattt cgcacagtcc gataaataat ttcttttcga accagccaaa
     1381 gaaataaaaa catcacaaca acgaataaaa acaatagaac cgtaaagaat gttaccatga
     1441 caactcgcct cgctttttct tctccagaaa ataggaaaag aatactgatt taccttctca
     1501 aagaaattgg acttgcagca cgccgcacgt ccaattgttt tctttattca aatgtatcat
     1561 attttgcaac aaccatgctt gctttttcat ctaataattc ttggtcctct gcagcacatt
     1621 gggcaacttt gaccacggcg cagtttgtca tttttgatac aacttcacca atgaccgttt
     1681 ttgtaaaacc aattggtttg catgcatatt gttctcctaa attaatcatt tcttccgtca
     1741 tcaaaatcct cctaaactgc tggaactttt ctccacatta ccactgctat ttctttggag
     1801 atttaactca ttgattttta tttacagtta aaaatcaacc ttacaggcat tatagcgtac
     1861 tgttttcgtt ttcacaatta aaacagctgt tgtatttaga agaatttttt tcaaaaaatt
     1921 aaaacatatt ccttaaaaac taattatttc ctacatatta aaatataata cttccatttc
     1981 caataaaaat acatttataa taggaaagat aaacagctga aaagggagat ttcaaatgaa
     2041 gaaaaaaacg ttcaaaaaac tattgtttct agggggcaca gctgctcttt tattaagcgg
     2101 tacaagttat tacctacata tccattctcc agaacataca atgaacactg cacaaaaaag
     2161 ttcaacacaa aaaacgaaaa agacaaaaga gaaagcagaa gttttactag atgttccatt
     2221 agagagccag tttgattctc cttctttaga aaatggctgt gaagtcactt cgctttctat
     2281 gcttttatct ttttatggtt atgaaacaac taaaaaccag ttagctgagc aattggatta
     2341 cgtccctgtt ttcaatgcag atgggactca tggcgatcct aatgaaggat ttgttggtga
     2401 tatcagtggc ggagactggg ctatggtcgt ctatgttccc ccagttgcct cccttgctca
     2461 gcaaatcgtc caaacggatt atcacacttt tccaaaaacc gatgctcaac tcgatgatat
     2521 caaaaaagca ctatctaaag gaaatcctgt ctggacttct gtgactatca attttgaagt
     2581 cccagatgaa actgatttta tgacttggac cacaaataat ggagaagtaa gagtcactcc
     2641 tcttgttcat gcttgtgtag tcactggata tgacaaagaa aatatttatg tcaacgatcc
     2701 ctatggtgta aaaaatcgag cagtaccgat caacgatttt tcggcgattt tcactgcaat
     2761 gggtggacag atgctaactt tggagaaaag ctagtaattc aaacaaaaat cccttatact
     2821 caagatacca aacctttgaa gggagcgtag ataatggaaa aattcacaca taaaaaaatg
     2881 gatccaaatg aaattccgat tatttttgtc cgtgactgca agggaaatgt tcaaggtaaa
     2941 gtctctatta atgagtggaa cgagcgtcgc agacctgcta ccctcaatga actggaaatc
     3001 aaattgtatc gtcaatctct tgtttattac gcagatcaag agtacgagaa agccaccgat
     3061 ttattgaaat ttctaattgc tcgaacagag tatactcgct ttgaatatat tgaacgttta
     3121 gcaaacatct atcatattat gaatgaacct gtcaaagaat atcagttatt ggacaccgtc
     3181 ttgtcagtag cagaactgat tgcccttcct gctggattag aaaagaaact agtacgccgc
     3241 cttttacgag taaagcaaca actatccgat caagaaaaat aacttgcgtt tttttaggaa
     3301 agtgctatga ttattttgtt gaataaatgg gatgtagcca aactggtaag gcacttgact
     3361 ctgaatcaag caattgtagg ttcgaaccct gccatcccaa tttgatgtgc ttgctgaaaa
     3421 aatgaacccc ctgtaaaaga acaatctttt tgcaggggga ttattgtatt atttttacta
     3481 cttgtattta gtttacataa ttaaattatg aataataaaa tcgggcgtat tcttaataca
     3541 aaaactgatt tacccaataa ttgctaatgc tttctccgga actttttctc taggaacttc
     3601 ctcatacgtt tctatgtgtg ctcctttatt gctaattttc aaataatgat tttcttttaa
     3661 cacagaaaga ccattaaatt caaccgttcg ttctttccca ttggcatcag cagctttctg
     3721 cacatacctt gctgtaccat attcatttac ttcctctggt ttttgtgtct ttacatagac
     3781 ctctcctttt tcaactaatg gatttagctg atcaagtata ccagggattt ctccataact
     3841 tccttcagta taatatttca gtccaaatag caaaatacca ctaatcgccg ccagtccaat
     3901 caaatattta atcactttca tctttctacc tccttgttat atattcagta tatgggtcag
     3961 ttaaagaaat tccatccgtc ccaagttgga gatttttctc ctactttaga agcgagaatc
     4021 gagtgttttt ttagtaaaaa tgatcgttat ttgatattat tgacgtgtgg ataaatcagt
     4081 ttttctcgtt ttgtccatgt aaaaaatcat gttgatagca aaggatgtgt tcaaaatgaa
     4141 tcaagaagaa ttatttcaaa aagtcaagga aatgattaag aacggcaatt tcgatggcgc
     4201 aaaacgattt atcgaagaac ataaagaaca attaggacct tataaagaga aagcccaaaa
     4261 tcttttaaaa gatgtaaata tcgacagtgt caaaaacaaa tttaaaaatc tattcaaata
     4321 agtaaaactt tcacttttgt aaaatcaaag gaggacaatg ctgctgcatc gtcctccttt
     4381 ggttcttttc tgaatacttc atactaaaat aaacgtgtcg gatcgtaatg ataagtcaca
     4441 ttgccgttca gtgaggcttt tcccaccaca tatttacgat tctccaactt cagccacgct
     4501 tctcgaaaag ccattaattc ttctcttttt acatcaatct tttcgatttt tccatcgatc
     4561 aaatcttgaa taagttgttc atatggattc atttttttcc tccatctgct gtcaatcaat
     4621 aagttgtaaa aataggttca tatgcttttt tggtatctag atcttctctg actttgactg
     4681 tcgtataaat aattttttct actgggatac tataataact tccttcacca ttattgaatc
     4741 ggtgaacgtc tttctttgct aaaataccat ttattttatt cgtcagtaca cgttgttcga
     4801 cactgttact tacaacatag taaatcaccc gaatattatt gatcaaatgc aaatcgattt
     4861 ctaacactac atgatccatg aaaatcccac tccttctttc actttgatta tagcaagttt
     4921 ctcctctaat ttcaaaatcg atacagattt taccggataa atccacaaaa ctgcttgcgc
     4981 catttcgcac aaagtgttat tttgtatcat ggactttatt tatcggaggc aatagtatga
     5041 tcgcgatcgg tcaatttgtt ttttatattc ctttttttat tatgataagc attcttttct
     5101 attacataaa atggacaaaa aagaagtttt cagttttact ggcctcttta cctgctgtat
     5161 attttactta tcaaattttt tcttttaggc attgggaaac aacgtctgta ttaataacac
     5221 acatcatcga attgacgctt tcagtaattt ttcttattat ttggatctat tttttatata
     5281 agaatcagaa ttgaatccct cgcatgttta aaaagaaaac gattaaagat gcagcaaatt
     5341 tctgccgatc tttaatcgtt ttttctattc tgttatacca aaaaaatgtt tgaatcggtg
     5401 aaggatcgtt ccttgtttta attctataaa ttcttgtgcg atcgggtact tttcttccaa
     5461 attttctttg ttcttttcga tcaggctttt cgcttcttca tattttttat ctgcacatag
     5521 tgcttttact tcctgtaata cttttcctgc ttccatttgc ctcaccctct tgccatttta
     5581 ttgctttaag ttttatttaa gttatacgca ttattctagt ttcatcccaa ataacctttt
     5641 ttcattttta ctcctcgaac taatcagttt tctaaaggct gattggttcg tcttttttat
     5701 ttttcctcca tttcattctg ctcttctgtt aatttatcta atgctttgat tgatgctgcg
     5761 gctcttgcat aatcatagct gtataattcc ataaatttat caggcagaac aaaccacgct
     5821 ggatgataac cgttagctgt gacagggaat cctttatctt gttggttatc tccatcccat
     5881 ctcagagcaa cacctttttt tcctttccac tttactaaag cgatcgagta tcccttcttt
     5941 gtttgtgtgc cgtcttcaat aattgctaaa atttctattt tttcttttgg cgcacggact
     6001 tcttgaggac gaaccatttt ctattcctcc cttatctcat tacttcacga ccaacacact
     6061 gcaaggggca tgtgatacga cataagaagc ggtcgatcca actaatgctt gttgtatagc
     6121 accttttcct gtcgctccca taacgatcaa atcaatattt tcttgtccag ggatgacatt
     6181 ggcaatcaaa tttcttggat ctccagtttc aactattgcg tggatctcag caatgccgta
     6241 ctctttggca tcattgattt ttttcagcat ggctacttct gttctttgtt tttcatctgc
     6301 atagattttt gaaaaggcat aggcactatg ggtcagctca actttgttga tgattgacac
     6361 gataaataag tgggcttcat tgtcctttgc taagtcaagg gcttcagcga acgctttgat
     6421 cgattgtctt gatccgtcaa ctgctaccat gatgttctgg tatcttttac tcattggaac
     6481 cgcctccttt ttcttttatt gtaacatctc aagcaaaaat acaaaaaata tacgcaatat
     6541 gtaaataaaa tgatgaacaa aagcaatttc tttcaagtta tttatacatt tcttttctca
     6601 tcagaacacc tgttctaatc ccattatttc tgcattatgt gaaattcctc atcatttttc
     6661 acatcgagcg aacatcattc tgttacaaaa aacg
//
LOCUS       DACGLI010000093         6173 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.099, whole genome shotgun sequence.
ACCESSION   DACGLI010000093 DACGLI010000000
VERSION     DACGLI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.099"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            725..811
                     /locus_tag="IXT22_002693"
     CDS             725..811
                     /locus_tag="IXT22_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4864007.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IXT22_002694"
     CDS             complement(932..1621)
                     /locus_tag="IXT22_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864008.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IXT22_002695"
     CDS             complement(1628..1906)
                     /locus_tag="IXT22_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864009.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IXT22_002696"
     CDS             complement(1866..2780)
                     /locus_tag="IXT22_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4864010.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IXT22_002697"
     CDS             complement(2762..3142)
                     /locus_tag="IXT22_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAQ4864011.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="IXT22_002698"
     CDS             complement(3592..3879)
                     /locus_tag="IXT22_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4864012.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="IXT22_002699"
     CDS             complement(3899..4123)
                     /locus_tag="IXT22_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAQ4864013.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4763..5296)
                     /locus_tag="IXT22_002700"
     CDS             complement(4763..5296)
                     /locus_tag="IXT22_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4864014.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="IXT22_002701"
     CDS             complement(5317..6159)
                     /locus_tag="IXT22_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAQ4864015.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DACGLI010000094         5946 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.100, whole genome shotgun sequence.
ACCESSION   DACGLI010000094 DACGLI010000000
VERSION     DACGLI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.100"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..813
                     /locus_tag="IXT22_002702"
     CDS             <1..813
                     /locus_tag="IXT22_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAQ4864016.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="IXT22_002703"
     CDS             807..1229
                     /locus_tag="IXT22_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864017.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2399..3367
                     /locus_tag="IXT22_002704"
     CDS             2399..3367
                     /locus_tag="IXT22_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4864018.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3384..3908
                     /locus_tag="IXT22_002705"
     CDS             3384..3908
                     /locus_tag="IXT22_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4864019.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            4284..4565
                     /locus_tag="IXT22_002706"
     CDS             4284..4565
                     /locus_tag="IXT22_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864020.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4567..4983
                     /locus_tag="IXT22_002707"
     CDS             4567..4983
                     /locus_tag="IXT22_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864021.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            5605..>5946
                     /locus_tag="IXT22_002708"
     CDS             5605..>5946
                     /locus_tag="IXT22_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAQ4864022.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2255 a         1017 c          964 g         1710 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
     1441 actttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1501 ccgtaggacg tactgaaagg gtgggattta tgagcgaact aatgcaaaat ttggctagca
     1561 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
     1621 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
     1681 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
     1741 cgtttgaaac gtctaagtat ataaatatat aagagtaggt ttaagagtgc ttaaatcgaa
     1801 ttttagaggg cattcagaca actttagggt tgttagggct tgccctgacc gcctgtaagg
     1861 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
     1921 gctcatagct tctcaaagag ttccttatga acatttttag caaaggagcc ggaagcgact
     1981 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
     2041 ttcccagttg agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
     2101 ggaaattttg tccccctctt ttataatctc tttttaaacc tctttttaaa cctctttacc
     2161 gtcggctata tccttactct cccaagggaa tgacgctttt atctacatcg ttttgtctgt
     2221 ttatctacat cgttttgtct gtttatctac atcgttttgt ctgtttatct acatcgtttt
     2281 gtctgtttgt acattgaatt agtacatcga cgatgttaat ataagatgta gataaacagg
     2341 cattttgtat ttcataacgt gtatctcttg tgcgagtaag aaaggagcta ttttaaatat
     2401 gtctaatgaa atcgtaaagt atcatcatga attaaataca attccgttgc gaaaatttac
     2461 accagtcgaa atgaatttgt tcttttctat cgtatcaaga atgcgtgatg taggtgataa
     2521 aaaagtacaa tttacattcg agcaattaaa agatttaagc aattataaag caactgcaaa
     2581 tgttcgattc atagatgatt tagaaacaac gtatgacaaa ttaatggatt tacgttttgg
     2641 tagaagaagt gctgacggtt tgcaacgtga acgttttgtt ttatttaatc aatttaaaat
     2701 cgacggaaaa tctgatattc cttttgctga aatacaagtt catgaaaaag ccttaccctt
     2761 acttaataat cttgaagaat gggtgcgcta ttctctccaa caattcaatg aattagaaag
     2821 cagttattca aaaacaatgt ttcgattact aaaacaatac agaaccaaag gtttcgctta
     2881 tttttcaaaa gaagactttc atgaattact tgatattcct aaaagttaca accaaggtac
     2941 gattgatcaa cgtgtgttca atccaatacg acaagaacta accgcaatct ttaaaggttt
     3001 aacaatcaaa aagaaatacg gaaaaggacg gggaaagcct gtcattggct atcaatttac
     3061 atttaaacct gagataaaaa aatcagacga ctttaacaaa catgccccaa caaaagaaga
     3121 acaaaacaaa gcattagaac tagctaacca acaagttcaa tctgaaaaag cacctacttc
     3181 attacaagaa aaaatcaaag aacaaaagcg aaaattggaa cttttacaac agttagaaaa
     3241 gttagaaaga gaacaaaata cccaaaataa agaaaataat gcacaaaaat cagagataaa
     3301 ttccgatatt ccttcagaac taaaaaaaga cttattagac aatcttcaaa acttattcaa
     3361 agattgaggg gtttttagat tttatgacag aaaaaacaat caaagaactt gctgaagaat
     3421 taggagttag taaaacagca attaacaaaa aagtttctga cgaaaatcga aaactttggt
     3481 tttcgaaaat cggaaacaag tttgtgatta atgaaaccgg acaaaaggct ataaaatcaa
     3541 tgttttttaa cgaaaacgaa aactcaaatc aacaactagt tggcgaaaaa acgaaaaccg
     3601 aaaaccacaa aaacgccaac caagttcccg aattagaagt cctttctctc ctagaacaac
     3661 agttaaatca aaaagatatg caactacaag aaaaagacga gcaaataaaa caaatgcaaa
     3721 aattactcga ccaccaacaa caactcaccc tgcaagccaa ccaacaaatc gagaaactgc
     3781 aggaacaact acagttgact tatacggaag aatcttcgga aaataaatca acgactcttt
     3841 ctgaagaaac agaatcgata gaaaaacaat caaaggcgga gaaaaaatgg tggcaattct
     3901 ggcaataaaa ccagcaattt aaattaataa aaattgctgg ttttattctt ctttttgctt
     3961 ttgcgagcag agcaacatgg acccatgttg cgatattttg gtggcgcccc aatccccgtt
     4021 ttttcgttga atcttactcg gactgcactc gttttacagc tgatttttct gaattttgaa
     4081 agagcataag gaaacgtggt atcactttct tacgaaaggt gctagatagg ctgtgcctat
     4141 cacgtttctc agaaaaaaat ttgctatcac ttttttgcca ttgtggctag gctatgtata
     4201 gtgttttggc gaaaaatagc tatacaaata ctatatttgt atggtataca taaattatac
     4261 gctgatacga aaggaaaatt tccatggaca ttttagttcg aaatatcaat cccaaaatta
     4321 ttgcaagaat agataaacgt tgtcaggaac tcacaaccaa aacgggcaaa aaatggagtc
     4381 gaaataaata tctaaaagtt ctaatcgaaa gtgattttga ccgtcaactt atgaattaca
     4441 aaaaagatca attcgattta ttactcgaaa aatttattgc cattcaaaca gaaaatacga
     4501 acatactgaa tgactatgtt cacacaaaca accaactcat tgaaacactt atcggaggaa
     4561 tataacatga gaaaaacttc tgttcaaaaa cacgtaaccc tttatcccag tcacgttgac
     4621 gttttagatt ccatcatcga aaaaaatcca gacgtcaaca attattcaga agccattcgt
     4681 tttttatgta tgagttatga acctgatacc aatacaacca caaccagtaa ccaagcaaaa
     4741 ctcaatgcca tgggaaaaga aatttctatc atgacagaaa tcatggcaga atttgctgat
     4801 ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtgta tcaagaagtg
     4861 aaagaaaaaa ttgaaaatca actcaatcct tcccgacgaa atcaacccaa aaatcgtcaa
     4921 aaagaaacca atcaaacctt tacttctgga aattttgacc caacaaactt tctaaaaaga
     4981 taaaaaaaga aaccgatccc taaaaaaatt cctcgatttc tttttaggga tcagtcttcc
     5041 agcaagattt gcaagttggt accaacttgc gaaaaaaaag aaaaatccgc ttatgcaact
     5101 tcttcttttt gtattttggg gcgctacccc aatccccaag tatcggttat ttaatagcgc
     5161 ggaaatccaa agaataggac gtaccctgaa acaaaaaaag actgctctca cgagcagccc
     5221 aaaatgagat tatcctattc atcaacataa aaatattaca aagtgaagaa ctagagaaag
     5281 acaaaaaaag catatcaaat cctctcaaaa ataacaagtc tttaaaaaat gacagataaa
     5341 aatgcacaaa gaactaaaaa agagaaatcg cgtaaaatca agcattagaa gctagtaact
     5401 agctagacca attaaaaatc acaaagtgag cgtctctatc cattggtaga ggggctactt
     5461 ggcatagtcg acattatgtt aactaacgct ataaataacg attatgttcc caaaacaata
     5521 ttttatgaac tataacaaaa atttgttatc gcatattgta tattttaatt ataggtgtat
     5581 accacttaaa tttaacacaa aggcgtgatt attttgaaac ccaaaaagaa aatttatcta
     5641 ggtctcctct tttccttgat gattggaatt tttagtatag gaattacaaa tacctatgct
     5701 tcagaaaatt ctaatttcaa tatcaactcc caaccaattg aagaacaagc aattaatttt
     5761 gcgaaaactg attttgaaca ctccataact tcaattcttt taatggaaaa taacaccgaa
     5821 actgatatta actatactct tggttcgcca tttaaaatgc tcgatggaga aaatacggca
     5881 aatagttcta ttttctttcc agtattttca gacgctgata atacgattaa atatatttat
     5941 accgtc
//
LOCUS       DACGLI010000095         5866 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.101, whole genome shotgun sequence.
ACCESSION   DACGLI010000095 DACGLI010000000
VERSION     DACGLI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.101"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(1122..1520)
                     /locus_tag="IXT22_002709"
     CDS             complement(1122..1520)
                     /locus_tag="IXT22_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864023.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KIAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1736..2791
                     /locus_tag="IXT22_002710"
     CDS             1736..2791
                     /locus_tag="IXT22_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAQ4864024.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQNI
                     LSFSLANLARLEDQSDDVLTANLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2811..3164
                     /locus_tag="IXT22_002711"
     CDS             2811..3164
                     /locus_tag="IXT22_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864025.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3346..3642)
                     /locus_tag="IXT22_002712"
     CDS             complement(3346..3642)
                     /locus_tag="IXT22_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864026.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3646..4464)
                     /locus_tag="IXT22_002713"
     CDS             complement(3646..4464)
                     /locus_tag="IXT22_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4864027.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4690..4911
                     /locus_tag="IXT22_002714"
     CDS             4690..4911
                     /locus_tag="IXT22_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAQ4864028.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4913..5179
                     /locus_tag="IXT22_002715"
     CDS             4913..5179
                     /locus_tag="IXT22_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4864029.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5292..5831
                     /locus_tag="IXT22_002716"
     CDS             5292..5831
                     /locus_tag="IXT22_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864030.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
BASE COUNT         2059 a          978 c          870 g         1959 t
ORIGIN      
        1 tcctacgcac ctcgagtgta aaatttcttt attcctccca cgctccatgt tattttatat
       61 ttcctttttc atgttatttt tatccagaaa ccgatcaagt ttttacctat tcccaaaatc
      121 catttattcg ttattttttt cactgattaa gaataattat ttgatgctta aattagctaa
      181 aaaagcgatt tgttactgat ataatcatga tattgcagct gaattaggcg gaaagataaa
      241 atgttcgcaa aatcaaagta tcaattatct tgttttttta taaatttgta agtaaaaatc
      301 taaaaaagtt ttcttttaat tggtatatgt attaaaatca catttaatca cccataaagt
      361 atgcgctttc atttttttgg atgagattaa tatcaataaa taacgatgta aaaatcattt
      421 attatgctct tttataagga tattaattga tctaatttga aaaaaatcaa aatttaaatg
      481 ttttaatatt acaaataaaa tcatgttatt gtaaaatggt ataaaaaagc taaatattct
      541 atttttgtta ttttattagc aggaaaattt aaatagtttt acaagaatcc gtagaaatat
      601 attggttttg ccttcagatt aatactggat catattaatc tgaatataat atatgaacta
      661 ataaatagct taacctcgct attttgtttt ttctgatcac tatctataca gcattagtaa
      721 atagaatttt aaaaataaaa aaattaagac aaaaaagtat caacataaac atatacatat
      781 acacgtttat gttgattcac ttaatttgtc ctttaaaaag cacttatttt aatataatgt
      841 tattttataa tcttattaca agctgattgt taggcgttgt cctttcatta catttattaa
      901 cggttatttt attgtttaat ttattaatta tttttgatct aaaacttagc ttaacaaata
      961 aataattaac caaccgccag ataaaaatgc gatcattgct aatacataag caaagataaa
     1021 aatatgttcg atcagcttaa accctgatgc gattaagcag accaagtaaa atagaaattc
     1081 tcttacagat aatggtaatt ttctaactag catactcata attaacaccc caaagtaata
     1141 ttgtattttg aacattttac atccaataca gcatcaatca accattgcca atcaaaaata
     1201 caaggcttca ttgaagtatg tttttcagat gaaaagatat aatataattt cttcggaata
     1261 atattttcag ttgttgggat caagctaaat ctaataccgt ctaactcata gctaccagct
     1321 ttctctccat taaaaatttc cttagcactt tcttctaaag aatcaaaata tttttcgaca
     1381 gcaatctttg aagcttttac tattgaagca tttccctttt cgataaaatc tgcttttgtt
     1441 ttaccgacaa taagtaattc ttgatcagta aaatcttcta aaataatggt agtgtaattc
     1501 ttatttcttc tcaatcgcat caggatcact ccttaatata atttatgttt ttataatatc
     1561 ataataagat aaatttgcaa gcatttattt acaccttttt atttacactt tattataatt
     1621 aattagactt ttatgattgc atttttttct tataaacagt tgcaactaat agtaaatagg
     1681 tgtaaactat tttcgtaccg aaataccata aacacaaaca gaaagaggtc ataccatgaa
     1741 agaaccatta ttgttttccg ttgacttagg gaataaatca gtaaaagaaa tgagtacaca
     1801 cgtttctcca ctctcacttc cctctcgtat tttgaacaaa aatatcatta attcaggacg
     1861 tttttctaat ataggttcct cattaaaacg atcactaaac gtttctgaat atagcctagt
     1921 aaacactact gaaagctatt actttgggaa ggatatacac gagctaggaa aagatgacta
     1981 cgtgatagaa tcactaggtt ttgggatcag cagatacaag caggaaacct accaaaatat
     2041 cctatctttc tctttagcta acctagcacg tttagaagat caatctgatg acgttttaac
     2101 cgctaatcta gttttaggtc tgccttcatc cgactatacc gaaacaatcg tcaaatacgt
     2161 gatgcaacaa gccacacgac aacattcagt tgaagttgac ggtaaagctt ataatataaa
     2221 cgtagatacc gtttgggtac tgccacagcc gattggaaca ctatataacc tcctacttgc
     2281 tgatgatggt agtgtacaag atgaaacatt gatcagtcag aagatcggtt ttgttgatat
     2341 tggtggtggc acgaaacttt ttgatgttgt ccaaaatttt gaaattgacg aaaacaaccg
     2401 tgaacaaaag gataccggta tttttacttt atataatcgt atcgtaaata tgcttgacct
     2461 tccgatcagt cctaatgctt tccaacttga aaagattatc cgagaaggca aagaaaaagg
     2521 cgtatatcta tttaaaccaa gcggaaatga aagttttgat atttcagaag tagttgaaag
     2581 agaaataaaa acatacacca atatggttgt tgcagaagtt ttagctacat tcaaaaactt
     2641 cacaacctta gataaagttg tctttactgg tggtggggct tctattatcg acaaacaact
     2701 tgtaaaagat aaaattccgc ataccttgtt tgttgaagac agtgaatttt ctaatgtaaa
     2761 aggcttttac aagtttggtt taactcaata aaacagcgaa ggagatcaac atgaataagg
     2821 gaaaatcaga gcgttatgta gttataatca atagagaaaa ggttagcgag ttacctttag
     2881 cagagtttct tgaatctgaa tatgaaacac taggcgttaa atactctcag acgatcaaaa
     2941 aagctttgaa tctatatcgg cgtgtaaaga acaatgaagt tacaattatt gaagcaggca
     3001 acgatagaaa cgatagcaaa gtagctgaag taaagaataa accaactgat cataacccta
     3061 ttcaacaagc gcatccttca acggttacat ccgatcattc agcaaagaaa gaaaagccaa
     3121 tgctaaaagg gttcaatgca ccaagtaaca aagacttact ttaaaaataa aaaggcgagg
     3181 ttacaatacc tagccttttt attatgtaca aatacaaaca taaacatata cgtatacatg
     3241 tatataaaca tgtatacgta tatatccata aacacgtata cgaaatttag ttaagctata
     3301 cctaaccgct tattccaata aaaaaagtga tcagctttaa actgatcact caccaaaaac
     3361 ttcatcatac aagttatcta tcatttcacc aagtaaagct gaatctgatc gaattcctaa
     3421 cttttcgctg attttagata gtttctttct ttgtgatggt tgaagcgtga attgataatt
     3481 tttcttcttt tcagaactat cactttttag tttagctacc aaagaacttg ttgtttcttt
     3541 aggtgtttgt ttaggttctt caactgcttc aaccacttca ggaacttctt ctacttcagc
     3601 ttcagcgaat tttttaaatc tattttcttt cacttcaatc actccttatt cttgtgccgt
     3661 atcaattatt ttgttgtata gcgtaaacgt gctttcaaag aaatccttat tcttacgata
     3721 gatattctta tccttagcga actcagcaat attcttacct tctaagctag ttgcattaag
     3781 caattccttc tcttgtacat atccaagata attagataac gttggtacca attctaggaa
     3841 ctcacgactt gaattagtat tatgtttgat cctgctaccg atcgtagcgt atttagtttc
     3901 catcagtgtt tcaccagtct taatatcaat caactgtttt gctagtgcat caatatcttt
     3961 accaagctta agcaaagctt caaaaccatc tttagatgga tcagaaatgc ctacgacaag
     4021 atcagataca gcccaagcat tttgagctag tagacctgca tcattatgag tatcaatcag
     4081 aattagatca tacttctctt taagctgttc atagttaaca acgatccatc taaacagtag
     4141 ggttctgttg ttaggcatat cacgcatttg catctcaact tgttttaaat cttcacctgc
     4201 tactaaaata tccatgttct catttatagc taaaggttca gctgatccat gaagatataa
     4261 atgattgatt gtattctctc ttttcgcttt actgaaagca tcaggaaatc gttttgatag
     4321 gttttgcgac ttatcttcat caatatacag caccttcata cctaaatttt cgacagcata
     4381 tccacctaga ttgtagattg ttgttgtttt acctgttcca cctttttcaa tgtttccagt
     4441 aatgattgac aacttctttt ccatgattaa acctccctta ttaatctttt gtaactccat
     4501 tatacactat aaacacgttt atgtatatat ttatatacat aaacgtgttt atatttatat
     4561 ttgcttttat attctacaac ataaacatat atatgtatat gtttatgttt atgtatatat
     4621 tcaaatatat aactattgca tttgtcatac aatcgtagta caatgtaatt gaaaaggagt
     4681 tgataaacta tgccagtaat aagtattcgt gtatctaaag aagaaaaaga ttttcttgaa
     4741 aaagttgctg aattcaacgg agataacatt tctgaattta tgcgtagtaa ttccctgcaa
     4801 acagcagaaa cgttagtaga ctttgccacc tacaagcaac taatgaaaga gcatgaggaa
     4861 aacgatcaaa gtatttccca cgaagatatg ctaaaagagt taggcttata agatgactta
     4921 ccaagtaaga tatgaacgtg aagctcaaaa agcgctaaaa aaaatggata agtttcaggc
     4981 aaaggttatc ctaaactgga tcgagaaaaa tcttgtaggc actgatgatc caagaaagca
     5041 tggtaaaggt ctaacagcta ataaatcagg ctactggcga tatagggtag gtgcataccg
     5101 tataatagct gatattagcg agcatgaagt gacaattctt atattgtcta ttggtcacag
     5161 aagtgaagtt tataagtaac agacaagctg ataaggcttg tctgtttttt tgttaaccca
     5221 acaaaatcac tgtttacgat cccactttac ctaaaaaaga acaatatcct cttgatatta
     5281 tacacaccag tgtgtataat ataagtgtaa acaagctaat taactttcaa aaggagcgat
     5341 tttttatggg atggtatggt gattattcat cagcaaatga agtgatcgaa gaaaagaaag
     5401 ggtacgccaa aaatggtttg gaaatcgtag gtaccaaagt aacgaagacc tatggaatta
     5461 tccttttcaa agatgcagaa ggaacctacg atattgacag cttcatcttt cgagatgaaa
     5521 tgtacaaacc aatctacttc ttaaatgaca gtcctgctta ctttaagaaa attccgaaaa
     5581 aatggttgaa attctttgtc ggtgatcaag aaaaaatggt taagctacaa ctagatagaa
     5641 ttaaagaaga aagcaataaa ccaaaacttg atgacttatt agttgcaggt aaaacttact
     5701 caatctggga tggatcgtat gtcgctgtct atcagtataa actcaaacgt agctttattt
     5761 ttcgactaca agatggatca ctcactcggt tcactcgact atcagcagga gatgttaagg
     5821 aagtaaccta aaacttaaat acataaacat aaacgtgtat acgttt
//
LOCUS       DACGLI010000096         5727 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.103, whole genome shotgun sequence.
ACCESSION   DACGLI010000096 DACGLI010000000
VERSION     DACGLI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.103"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            196..921
                     /locus_tag="IXT22_002717"
     CDS             196..921
                     /locus_tag="IXT22_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864031.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="IXT22_002718"
     CDS             911..1420
                     /locus_tag="IXT22_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864032.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="IXT22_002719"
     CDS             complement(1490..2938)
                     /locus_tag="IXT22_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4864033.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="IXT22_002720"
     CDS             complement(2938..3654)
                     /locus_tag="IXT22_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4864034.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="IXT22_002721"
     CDS             complement(3635..3985)
                     /locus_tag="IXT22_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAQ4864035.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="IXT22_002722"
     CDS             4129..4902
                     /locus_tag="IXT22_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4864036.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="IXT22_002723"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="IXT22_002723"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DACGLI010000097         5694 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.104, whole genome shotgun sequence.
ACCESSION   DACGLI010000097 DACGLI010000000
VERSION     DACGLI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.104"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(46..2970)
                     /locus_tag="IXT22_002724"
     CDS             complement(46..2970)
                     /locus_tag="IXT22_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAQ4864037.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3116..3691
                     /locus_tag="IXT22_002725"
     CDS             3116..3691
                     /locus_tag="IXT22_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864038.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3905..4600
                     /gene="vanR"
                     /locus_tag="IXT22_002726"
     CDS             3905..4600
                     /gene="vanR"
                     /locus_tag="IXT22_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4864039.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4578..>5694
                     /locus_tag="IXT22_002727"
     CDS             4578..>5694
                     /locus_tag="IXT22_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4864040.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVEL"
BASE COUNT         1754 a         1078 c         1077 g         1785 t
ORIGIN      
        1 ctaaaatact ttgttttttt acctgtctac ttgacagggg gcagttcact ctgagttaaa
       61 atggtattct cctagtaaat taatatgttc ccaacctaag ggcgacatat ggtgtaacaa
      121 atcttcatta aagctacctg tccgtttttt atattcaact gctgttgtta ggtggagagt
      181 attccaaata cttatagcat tgataattat gtttaaagca ctggctcttt gcaattgatg
      241 ctgtatggtg cgttctctaa gctcaccttg ttttccgaag aaaatagctc ttgccaatcc
      301 attcatggct tctcctttat tcaatcctct ttgtattttt cttcttaatg attcatccga
      361 tatataattc aaaataaaga tcgttttttc tattcggccc atctcacgta aggctgtagc
      421 taagctgttt tgtcttgaat aggaacctag cttccccata ataagggatg ctgaaactgt
      481 tccctccctt atagaatgag ctaatcgcaa aacatcctca taattttctt taatgacctt
      541 tgtatttatt tgtccacgta aaatggcttc tagttttgga tactcacttg ctttatctat
      601 cgtaaataat tttgagtccg ataaatccct tattcttggg gcaaatttaa atcctaataa
      661 atgagtcagt ccgaatattt ggtcagtgta accggcagtg tctgtataat gttcctctat
      721 gtttagatcc gtctcatgat gtaacaaacc atccaaaaca tgaatcgcat ctcttgaatt
      781 agtatgaata atctttgtgt agtaagaaga gaattgatca cttgtaaatc ggtagatggt
      841 ggctcctttt ccagttccat aatgtggatt tgcatctgca tgtagtgatg aaacacctag
      901 ctgcattctc ataccatctg acgaagatgt tgtaccgtcg ccccaataga aaggcaattg
      961 taatttatga tgaaagttta ctaatatggc ttgggcttta ttcatggcat cttcatacat
     1021 gcgccattga gatacattgg ctagttgctt atatgtaagt ccgggtgtgg cttcggccat
     1081 cttgctcaag ccaatattca ttcccattcc taaaagggca gccatgataa tgattgtttc
     1141 ttccttatct ggttttcgat tattggaagc atgagtgaat tgctcatgaa atcctgttat
     1201 atgggccaca tccatgagta aatcagttaa ttttattctt ggtagcatct gataaaggct
     1261 tgcactaaat ttttttgctt cttctggaac atctttttct aagcgtgcaa gtgatagctt
     1321 tcctttttca agagaaaccc catctaactt attggaattg gcagctaacc actttaacct
     1381 ttcattaaag ctgctggttc tctccgttat ataatcttcg aatgataaac taactgataa
     1441 tctcgtattc cccttcgatt gattccatgt atcttccgaa aacaaatatt cctcaaaatc
     1501 cctatattgt ctgctgccaa caatggaaac atctcctgcc cgaacatgct cccgaagttc
     1561 tgttaaaaca gccatttcat agtaatgacg attaattgtt gtaccatcat cctcgtataa
     1621 atgtcttttc catcgttttg aaataaaatc cacaggtgag tcatcaggca cttttcgctt
     1681 tccagattcg ttcattcctc ggataatctc aacagcttgt aaaagtggct catttgcctt
     1741 tgtagaatga aattccaata ctcttaatag cgttggcgta tattttctta gtgaataaaa
     1801 ccgtttttgc agtaagtcta aataatcata gtcggcagga cgtgcaagtt cctgagcctc
     1861 ttctactgaa gagacaaagg tattccattc aataaccgat tctaaaacct taaaaacgtc
     1921 taatttttcc tctcttgctt taattaatgc ttgtccgatg ttcgtaaagt gtataacttt
     1981 ctcatttagc tttttaccgt tttgtttctg gatttcctct tgagccttac gaccttttga
     2041 taacaaacta agtatttgcc tatcatgaat ttcaaacgct ttatccgtta gctcctgagt
     2101 aagttgtaat aaatagatgg ttaatatcga ataacgttta ttttcttgaa agtcacggaa
     2161 tgcatacggc tcgtatcttg agcctaagcg agacagctgc aacaggcggt tacggtgcaa
     2221 atgactaatt tgcactgttt ctaaatccat tcctcgtatg tattcgagtc gttctattat
     2281 ttttagaaaa gtttcgggtg aaggatgacc cggtggctct tttaaccaac ccaatatcgt
     2341 tttattggat tcggatggat gctgcgaggt aataatccct tcaagctttt ctttttgctc
     2401 atttgttaga gatttactaa ccgtattaaa tagcttcttt tcagccattg cccttgcttc
     2461 ccacaccatt ctttcaagtg tagtgatagc aggcagtata attttgtttt ttcttagaaa
     2521 atctatgcat tcatgcagta gatgaatggc atcaccattt tccaaagcta attgatgaag
     2581 gtacttaaat gtcattcgat attcactcag ggtaaaagtt acaaagtcgt attcacttcg
     2641 aatttctttc aaatgatccc aaagtgtatt ttccctttga ggataatgat caagcgagga
     2701 tggactaaca ccaatctgtt tcgatatata ttgtatgacc gaatctggga tgcttttgat
     2761 atgagtgtat ggccaaccgg gataccgaag aacagctaat tgaacagcaa atcctaaacg
     2821 gttttcttcc ctccttcgct tattaactat ttctaaatcc cgtttggaaa aagtgaagta
     2881 ggtccccagt atccattcat cttcagggat ttgcataaaa gcctgtctct gttccggtgt
     2941 aagcaattct ctacctctcg caattttcat tcagtatcat tccatttctg tattttcaat
     3001 ttattagttc aattatatat caatagagtg tactctattg atacaaatgt agtagactga
     3061 taaaatcata gttaagagcg tctcataaga cttgtctcaa aaatgaggtg atattttgcg
     3121 gaaaatcggt tatattcgtg tcagttcgac taaccagaat ccttcaagac aatttcagca
     3181 gttgaacgag atcggaatgg atattatata tgaagagaaa gtttcaggag caacaaagga
     3241 tcgcgagcaa cttcaaaaag tgttagacga tttacaggaa gatgacatca tttatgttac
     3301 agacttaact cgaatcactc gtagtacaca agatctattt gaattaatcg ataacatacg
     3361 agataaaaag gcaagtttaa aatcactaaa agatacatgg cttgatttat cagaagataa
     3421 tccatacagc caattcttaa ttactgtaat ggctggtgtt aaccaattag agcgagatct
     3481 tattcggatg agacaacgtg aagggattga attggctaag aaagaaggaa agtttaaagg
     3541 tcgattaaag aagtatcata aaaatcacgc aggaatgaat tatgcggtaa agctatataa
     3601 agaaggaaat atgactgtaa atcaaatttg tgaaattact aatgtatcta gggcttcatt
     3661 atacaggaaa ttatcagaag tgaataatta gccattctgt attccgctaa tgggcaatat
     3721 ttttaaagaa gaaaaggaaa ctataaaata ttaacagcct cctagcgatg ccgaaaagcc
     3781 ctttgataaa aaaagaatca tcatcttaag aaattcttag tcatttatta tgtaaatgct
     3841 tataaattcg gccctataat ctgataaatt attaagggca aacttatgtg aaagggtgat
     3901 aactatgagc gataaaatac ttattgtgga tgatgaacat gaaattgccg atttggttga
     3961 attatactta aaaaacgaga attatacggt tttcaaatac tataccgcca aagaagcatt
     4021 ggaatgtata gacaagtctg agattgacct tgccatattg gacatcatgc ttcccggcac
     4081 aagcggcctt actatctgtc aaaaaataag ggacaagcac acctatccga ttatcatgct
     4141 gaccgggaaa gatacagagg tagataaaat tacagggtta acaatcggcg cggatgatta
     4201 tataacgaag ccctttcgcc cactggagtt aattgctcgg gtaaaggccc agttgcgccg
     4261 atacaaaaaa ttcagtggag taaaggagca gaacgaaaat gttatcgtcc actccggcct
     4321 tgtcattaat gttaacaccc atgagtgtta tctgaacgag aagcagttat cccttactcc
     4381 caccgagttt tcaatactgc gaatcctctg tgaaaacaag gggaatgtgg ttagctccga
     4441 gctgctattt catgagatat ggggcgacga atatttcagc aagagcaaca acaccatcac
     4501 cgtgcatatc cggcatttgc gcgaaaaaat gaacgacacc attgataatc cgaaatatat
     4561 aaaaacggta tggggggttg gttataaaat tgaaaaataa aaaaaacgac tattccaaac
     4621 tagaacgaaa actttacatg tatatcgttg caattgttgt ggtagcaatt gtattcgtgt
     4681 tgtatattcg ttcaatgatc cgagggaaac ttggggattg gatcttaagt attttggaaa
     4741 acaaatatga cttaaatcac ctggacgcga tgaaattata tcaatattcc atacggaaca
     4801 atatagatat ctttatttat gtggcgattg tcattagtat tcttattcta tgtcgcgtca
     4861 tgctttcaaa attcgcaaaa tactttgacg agataaatac cggcattgat gtacttattc
     4921 agaacgaaga taaacaaatt gagctttctg cggaaatgga tgttatggaa caaaagctca
     4981 acacattaaa acggactctg gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa
     5041 aaaatgacgt tgttatgtac ttggcgcacg atattaaaac gccccttaca tccattatcg
     5101 gttatttgag cctgcttgac gaggctccag acatgccggt agatcaaaag gcaaagtatg
     5161 tgcatatcac gttggacaaa gcgtatcgac tcgaacagct aatcgacgag ttttttgaga
     5221 ttacacggta taacctacaa acgataacgc taacaaaaac gcacatagac ctatactata
     5281 tgctggtgca gatgaccgat gaattttatc ctcagctttc cgcacatgga aaacaggcgg
     5341 ttattcacgc ccccgaggat ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct
     5401 ttaacaacat tttgaaaaac gccgctgcat acagtgagga taacagcatc attgacatta
     5461 ccgcgggcct ctccggggat gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa
     5521 aagataagct agctgccata tttgaaaagt tctataggct ggacaatgct cgttcttccg
     5581 atacgggtgg cgcgggactt ggattggcga ttgcaaaaga aattattgtt cagcatggag
     5641 ggcagattta cgcggaaagc aatgataact atacgacgtt tagggtagag cttc
//
LOCUS       DACGLI010000098         5691 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.105, whole genome shotgun sequence.
ACCESSION   DACGLI010000098 DACGLI010000000
VERSION     DACGLI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.105"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            58..510
                     /locus_tag="IXT22_002728"
     CDS             58..510
                     /locus_tag="IXT22_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864041.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            524..1213
                     /locus_tag="IXT22_002729"
     CDS             524..1213
                     /locus_tag="IXT22_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864042.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1338..3689
                     /locus_tag="IXT22_002730"
     CDS             1338..3689
                     /locus_tag="IXT22_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAQ4864043.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3769..4164
                     /locus_tag="IXT22_002731"
     CDS             3769..4164
                     /locus_tag="IXT22_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864044.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4489..5106
                     /locus_tag="IXT22_002732"
     CDS             4489..5106
                     /locus_tag="IXT22_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864045.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5147..5446
                     /locus_tag="IXT22_002733"
     CDS             5147..5446
                     /locus_tag="IXT22_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864046.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5480..5647
                     /locus_tag="IXT22_002734"
     CDS             5480..5647
                     /locus_tag="IXT22_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4864047.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
BASE COUNT         1996 a          751 c         1161 g         1783 t
ORIGIN      
        1 caattatctt atcgtagata tatattataa atttaataag aaagcgaggt gagaatcgtg
       61 aaaaaaacga tactaagtat tttttcagta tttacaatat taattggggg ctattttctt
      121 ttgaatttag attctgttaa ttcaaacgct caaataaaag atcaaagagt agctgaacat
      181 aataataaaa aaatgagttt gaccaaaaat atctattcta tgtcagatga agaattgtat
      241 aaagaatttg gtgatttatc cggggaacag ttagaagaaa gtattccagg aattagtgac
      301 tcagataaaa ttgttgtctt gtctgctggt gggcaattaa tgggagatgg caaatccgaa
      361 ttagttagtt ataaacaaaa tcacagacag tttattgatg ttaatactga ttccaacgct
      421 atttcgatta aggatctaaa agagctttta aatagtaaaa gaaatgaatt aaagcagata
      481 aaagaaacta attcagtgga attagagtaa aggaagattc attatgaaaa agatttttgg
      541 tgtttctgtt gggctactta tgatgttaac atttggaaat gcagtatatg ctgctgagaa
      601 agaagttatt tcagatccag agcagtacgc ctcacgatac tttgctgatt ttgaagaaga
      661 agataaagta cttgcattgc cagaaggtgg ttttttaaaa ggggaagcta aaattgtatc
      721 tatggataat ccagatataa ttcaaggttc atataattca gaaactgatc ctgcttcagt
      781 ttcagtgaca gaagcaaaaa aaattgttgc tgaaaaattc aaaaatgata ttgaaactac
      841 tccaattatg cctcgaggag catttccacc cgatgttggt actagcggac accttcttgt
      901 actagcagga ggaggaagct ataaatcaca gccatttagt ggtgcgggat ggcgttttgg
      961 aggtatgggt gtaaaaccag ctgatggtac aggcaacttt ttacgttgga aatcctacat
     1021 tgacgatgga agagtaggaa atgtaaatca agccaacgca actaaatctg gttctattca
     1081 aggaatggca ttgtatgctc gtgaaggatt caaatacttt gcaccaaacg ggcctggttg
     1141 gacaatgaat ataggtattt attacactta taatcctgtt gcaggtacgt attatgttgt
     1201 tcaaaatatt taataaaaca gcacaaagag atttctttgt gctgttttat tatttttagt
     1261 tgttgacaaa cactaaaata taaaatataa tcaacacata aacgaacgta tgttcggcaa
     1321 gaaagcaggg gatttttatg gatgagatgg ttttaagtac tcagaaatgg ctaaacaaga
     1381 aatacagtaa tgttacaggg tttgataagg ttccagaaaa tgggcgaaca gggtggccta
     1441 caatctatgg acttattgaa ggactacaag tagaacttgg tattactaat ctagtagcta
     1501 attttggacc taccactgaa aaaatgtacg ataatcaggt tactcctaaa tggggcaaaa
     1561 atctacctaa aaatattgta tttcttattc aaggtgcctt ttggtgtaag gggattaatc
     1621 caggtggctt cgatggggta tatactccat atttagatac tgctgtaaaa gagttgcaga
     1681 ctgatgcagg gtttaatgga agcgctgtaa ctggagtttt ggatgcgaaa tgggccaaag
     1741 cgttatttga tatgagtgct tttgttcttg ttcccggcgg agatagtaaa attagaaaaa
     1801 tgcagcaatg gttaaatgta aattatttag aatacacggg aataatgcct tgtgatggta
     1861 tttatcaaag aaattcaaat caagcattaa tttttgcatt acaagctgaa ctaggatatt
     1921 ctcccagtga agcaacaggg tcttatggta atgggacaac tagtaaaact tatcctgtgt
     1981 ctgaaggtaa ctcgggaaac tatgtaagaa taattcaata tggattatat gttaatggtt
     2041 attttgaaga cggtacattc gatggtattt tcactaaata tatgggttta gaagtactgg
     2101 cattccgaaa atttatggta ttgcctgaat atactgaaat agcagatgtt gttgtaataa
     2161 aaggactatt gtctagcgct ggagatatta gaagatctgc agatggcgca gatacttcta
     2221 cgcaattaac tagatctcaa atccaaacat tggttgataa tgatataaaa atagttggta
     2281 gatatcttac tggtactgtt ggaattggaa aagatgaacg aaataagtat ctaactacag
     2341 aggaattgaa taatattttt tctaaaaatt tatctgtgtt tcctatctat caagatggag
     2401 gtgcagcatt agcttatttt acttatgatc gtggcttatc agatggtaag aaggctatag
     2461 atgcagcaaa aaatctaaat ataccattaa caacagttat ttattttgct gttgatctag
     2521 acatgttagg ggaagaaatt cttgcatatg ctggagaata ttttaagggg gtatctgctg
     2581 taatgtcata tagcgggtat caaacgggtg tttacggaac aagaaatgtt tgttctcaaa
     2641 taatcaataa cgggtatgct tcgtttgcat ttgtttcaga tatgtcgact ggttatagtg
     2701 ggaatttagg ttttcctatg cctagacaat ggtcttttga tcaatttgtt gaatttacca
     2761 taggaagtgg caacggagct gttggtatcg atttaatcgc tacatcgggt agagatagcg
     2821 gatttaatga gttatcaaat gatactaata atgataatta cattgccaaa tacaatcaga
     2881 aggttataaa tcagatggta cgtgcgtatc aatatctatc acaagctggt cttgataatc
     2941 cttggaaccc tcatttgaca ttttatagat atgtaaatta ttctggtttg tcatgggaca
     3001 tcatttcttc tcctgtaaca gagcatgata gaaaaattta tgatgaatat aggaataaat
     3061 taactaatag cgagggcctg tataattatt ttatagatcc taatactggt tcaataatag
     3121 gtttgcctca cttaattgtg acgttacaat cacagatgtt tctagccgac acaatcaatg
     3181 atagtgtttc tgactttgca ggttggttag gagatttaat gacttgctgg ggtgaagtta
     3241 agaaattagg aatacaaatg gagcaaggtg tatttgcatt agtaggtacg gctgcaggtg
     3301 gaacatttag tctagaagat ttataccaag atgttgacgc ggtaaatgtt tataccttag
     3361 caaaaagaaa ttctgattca acagctttat cggctttaaa aacgtactat tgtgataagg
     3421 gtgctattga tagatttaat caatttgtta agaacagatt tggttcttca gataaaatcg
     3481 cttcagtaac aaatagttta ttagaaaatg acgaaacagt tgatatctta ggtgtaggga
     3541 taatttcatt tttcattgat aaaatagtta ataattcact tgggacagat tttacttatc
     3601 ttgattttat tggagatgag gggaaagttg caaatggatt ttctgaaaaa attattcaat
     3661 ttcaagaaaa tagaagtaaa cttaattaag aatcgtttac tatttaaaca gtgtcctttt
     3721 cctttttaaa tatatacgat aaaataagta tatgaattgt aaaaggacat gatgattatg
     3781 gaagaaatag aatggaataa tctgactcaa aataataaaa ataattctgg atgtggaatt
     3841 atctttatgt ttgttatagt tttgggaata gtagtacttt taataactgt caagatagta
     3901 gattactttg cgaatactcc tgaagaacaa atacagagaa aacttcctga gtttgaaaga
     3961 gtaccacctt atgatccaag agataattca tttcaagtaa aaaaattaaa agagtctcca
     4021 aatgaaatgt ggtttgaagt tacagttgaa tcaagcgact tcaaagaaaa aaagaaagaa
     4081 tacaattata ttgtaaaggc aaaagtatca aaaagattta tttttaaccc taaattagaa
     4141 atatatagtg ttgtaataga ataatagtgt taaaaaaatt gtaaaagtta aagaagtcaa
     4201 attctgatgt gaaaaataaa atataccatg gaagacataa aagaaaaact ggataactag
     4261 tttatttaat ggcagaccgt taaggcctgc catttttatg tattttagcg gaataaatat
     4321 aatcatgcgg gagtgtaaac ttactgtttc aaaaagtata ctttttgaca tgccttgatt
     4381 ttctttgttt atgtatggca taataaccac ataatacaat ttgaaacgtt tctgatttaa
     4441 tctgattgtt ttgaaacaat tttagtgaaa aaagggtaga taaaaacgat gagaaaattt
     4501 ttttatatcc gggtcagtag ttatgatcaa tcgatcgaac gacaactgat ttccgcgaag
     4561 gaattaggaa tccctgaaga atatatattt gtagaaaaag ccagcggcaa agattttaaa
     4621 cgccctgaat atcaattaat gaaacggatg tttcgaaaag gagatttact ctatctacaa
     4681 tcattagata gactaggcag aaataaacaa atgattttag aagaatggcg agaattaact
     4741 aaggaaaagc agattgatat ttctgtgtta gacatgcctc tgttagatac tgctagttac
     4801 aagcaactag atgggttaga gacgcttatc tctgacttaa ttctgcaatt actcagctat
     4861 atggccgaag acgagcggaa acgaattaat agccggcaaa gagaaggcgt agaagctgcg
     4921 aaacaaaagg gtgtaaaatt cggcagaaag aaaattgctt tacctcctga atttcctgcg
     4981 atctattctg actggaaagc aggaaagata actgcagtct atgctatgga tcaattgggc
     5041 atgaaacgaa atacctttta tcgacgggtg aaagaatatg aacatacctt gcaccacttt
     5101 tcttgataga tataacagct attagacggg aagggagagt ttgaaaatgg acttaacgaa
     5161 tcaaagggtc gtttttactg gaacgctgca gcaaatgaca cgaacccaag ccatcggttt
     5221 ggttcactct ttaaacggcc attgtcaatc aagtgttact tcaaaaacaa atttcctggt
     5281 ttgtggtcag tattctaagt cgttgtttga tgattctctc tatacaaaaa aggaacaaac
     5341 cgcgcgggac ttgattgcgt taggtcatga gattaccatt ttatcagaag tcgaatttta
     5401 tgcgttaatt agtcaacagt tgaaagaatg gcaacggtat ttataatcgt tagtaaaatt
     5461 tacaaggagg aaaattttta tgaagcgaaa atcttatgat cgttggggca ttgaaataac
     5521 tagttttaat cgaaatattg cttttcacgt ggagtgtgac tgtggggaat tagcaaaaag
     5581 tgtttatcaa aaaaattact tttactgtcc taaatgccat cgccgatacg gggtacatgg
     5641 aacatagaaa cgaaatagtg cggtagaaaa gcgaatgaat gtagtatatt t
//
LOCUS       DACGLI010000099         5585 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.106, whole genome shotgun sequence.
ACCESSION   DACGLI010000099 DACGLI010000000
VERSION     DACGLI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.106"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(488..1297)
                     /locus_tag="IXT22_002735"
     CDS             complement(488..1297)
                     /locus_tag="IXT22_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4864048.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="IXT22_002736"
     CDS             complement(1297..2043)
                     /locus_tag="IXT22_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4864049.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="IXT22_002737"
     CDS             complement(2061..2528)
                     /locus_tag="IXT22_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4864050.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="IXT22_002738"
     CDS             complement(2528..2938)
                     /locus_tag="IXT22_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4864051.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="IXT22_002739"
     CDS             complement(2949..3962)
                     /locus_tag="IXT22_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4864052.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="IXT22_002740"
     CDS             4179..4913
                     /locus_tag="IXT22_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4864053.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..>5585
                     /locus_tag="IXT22_002741"
     CDS             4897..>5585
                     /locus_tag="IXT22_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4864054.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQS"
BASE COUNT         1790 a         1184 c          920 g         1691 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatc
//
LOCUS       DACGLI010000100         5542 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.107, whole genome shotgun sequence.
ACCESSION   DACGLI010000100 DACGLI010000000
VERSION     DACGLI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.107"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(138..1091)
                     /gene="menA"
                     /locus_tag="IXT22_002742"
     CDS             complement(138..1091)
                     /gene="menA"
                     /locus_tag="IXT22_002742"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAQ4864055.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1104..2207)
                     /locus_tag="IXT22_002743"
     CDS             complement(1104..2207)
                     /locus_tag="IXT22_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4864056.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2297..3232)
                     /locus_tag="IXT22_002744"
     CDS             complement(2297..3232)
                     /locus_tag="IXT22_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAQ4864057.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3534..5468
                     /locus_tag="IXT22_002745"
     CDS             3534..5468
                     /locus_tag="IXT22_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4864058.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
BASE COUNT         1607 a         1088 c         1106 g         1741 t
ORIGIN      
        1 acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
       61 aaatataagg agctattttt atttggctgt tcttattact tgatgcaggg cagttttttc
      121 acaacctctt catgctgtta aatggcttgc ataatgattg ttagtaatag ccccaataca
      181 taactggcat tgaataagac catatttttg atggaatagc tgaaactgat aggctggggt
      241 aacgtttgct tgaattgatc caaatgcttc ttcacaattg gcaaggtcaa gaaggtgacc
      301 aagatcggcc attcatagat accgctcaac aaccccatta aaatcacgaa atagcaagca
      361 tacatcaata gctggaataa gactgttccc gcaggacgtc cgatataaaa aactagtgta
      421 tagcgatgat tttcaatatc acggtcaaga tcccgcaaat tattagccaa catgatattg
      481 gcaatcgtaa acaccaaggg taaggaagct aatacgattg ctgctatagc ccaaagattt
      541 cctaccaaag caaattgtcc agatgaaaag ttgactgtca gatcatagac atctgaaccg
      601 aatgtattga cataaacgac catggcaaaa attccaaggc ccatagtcac cccactgaaa
      661 atttccccta aaggcattcg agataaagga atcggtccga atgtatagaa tactccaata
      721 aaacaacaga taaatcccat caaaagtaaa agccaacccg tattgatcgt tagaataacg
      781 ccgataacaa aaacaaatgc aatcatagct aaaatcatgt ttcgaatcaa tacaggagat
      841 agatttctgc ggccaatgac attttcttca tacttatata cttcagaatg agccttttca
      901 taatccatgt aattattgat agcggtagtc gctaaatcaa aaactagcat tccaataaaa
      961 aataaaaaag tgtttagcca atgtatctca tgaaaaaaag cgatagagaa taatacccct
     1021 accgcaaaag gaaatacact agccaccttt gttcgtattt caactacttc taaaaagatt
     1081 tttagtgtca tggttcgtac tccttatttt agttcagaac ggtcacccat cgtgtaatgg
     1141 gagtcctccg ataatttgaa ggtgtctttg attggatcgg tcacatatac tttatcgtct
     1201 tttgtcacga agatcgcttc cgtcccgtta ttcaattcgc tttcgacgta ttccagtcct
     1261 tttttcacac ccattgaaaa gactgctgta gacaacccgt caccatcaat tgatttatct
     1321 gttatgatcg tgacacttgc gatatcattg tcgaacggat aacccgtttt tggatcaaac
     1381 aaatgatggt attttttgcc atctacttct aaataacgct cgtaaattcc agaggtaact
     1441 aatgttttgt tccgttcttt aatagaacct aaaacagatc cgcgagccat gttcggatct
     1501 tggatgccga ctgtccagtc ttggttttcg cctcttgggc tgtggcctaa gacatagaca
     1561 ttaccgccca agtcaacgat ggcagtggtc actccttgtt ttttcaagac tttcactact
     1621 tcgtccgtaa tgtaaccttt ggcgattgca cctaaatcga tgatcattcc tttttctttt
     1681 agataaacag ttttttcttt gtcatttagt tcgatcttat gataatccac taatttcaat
     1741 gcctgatcga tttcttcttg ggaaggtttt ctggcgtcat caaaaccgat tcgccataat
     1801 tgtgtgattg caccaatcgc catatcgaat ccgccttgag aatcttggct atattcgtag
     1861 gcccgcttga ctaacgtgta gacgtcatca gaaactttta ctggtttgat cccagcttgc
     1921 tcattcactt catcgatctc agaacctttt tgattgatcg tgattttatc accaagttct
     1981 tttactcgat cgaaggcagg tttcaatgct gattctttgc cttcatcata cacacggata
     2041 cgaacgtaag tccctaacaa gaactgttca tcagaatatg gatctttcaa tatcttggta
     2101 gctgctgaac tttcagtggt tgttttattt gctgagttgc tgcagccagt tagcaccata
     2161 aaagagatgc ccagtgtgat taaggaaaat agtagttttt tccgcatctt tttcctctct
     2221 tcattttgaa aggtgagacg actgcctaat ctggctatcg tcccaccctc caacttttat
     2281 tagtatgatt atgtgattat ttttctgtta cgatattatc tacttcgatt gtttgagtgt
     2341 cgcctttttc agctgcattc actaattgtt gtgcgtacat gatgaatgaa tgtgagctgt
     2401 gtgtagcacc tgtaacaact tctacattag caggtgagcc atcttcttcg cccattgctt
     2461 tgacgaattc gtcgttcaga gtagggatgt aagtttttgg ttctgtaccg ctttttgctt
     2521 tcatattttc attatattct gtatcatctt gttttgattt accgtctttg tcgatataat
     2581 caaagtttga ttcagttact ttgccgccag caactgtcat ttcgaattgc acacggtagc
     2641 cgttagagta gttcttttct tcaagcttgt aagtgccgtc tttcaaatca gcaccattgt
     2701 cgatttcgat tgtatctgtg ttaccagctt gagcagcttg gatcaattgt tgtgcgtagt
     2761 tttggaagct ttcagatgag tgagtagctc cagttacgac ttccacaccg cttgcgcttt
     2821 gtgcttttaa gaattggtca ttcaactcag gaatgtattt ttctgggttt gtgccagatt
     2881 ttgcttccat gtttttgttg tattctgcat cttttgtttt tgattcgccg ttttcattga
     2941 cgttatcata ttttgattca gtgattttgc cgtcttttac aaccatttca aagactgcac
     3001 ggtaaccatt tgaataattt ttttcttcta atttatatgt gccgtcttgc aaatctccgc
     3061 cagctacaac ttttgcagat gattctgttg tgctttttgc agtcgaagat tgtgctgtag
     3121 atgattcaga agaagagttt gagcttccgt tgtcatctgc gccgcaagcg cctaacacta
     3181 gagctgaaaa tgctaatacg gcaaatccag ttacaaaacg ttttttcttc attttaatac
     3241 cccaccattc catttctagt ccacaatttt tctttgtgat tcattataca ttctaatctt
     3301 tttagcctat aagtcaacta tttttgataa ataacccatg taatatttca aacgttttct
     3361 ttcagcaaat ttcgtgaaaa aacgctttat tttaaaattt gaaaaaaatc caaaaggagt
     3421 tagacaaaag aacagaacat ctatataata tatggagatt gtgtaataag tatcaaacta
     3481 aaagaattat catatattca ttatatagat agtctataag gagcggatga tcaatggcaa
     3541 agcaaaatat tgtcgttgta ggagcaggat atgccggtgt ttcagctaca aaatacttgg
     3601 caaagaaact gaaaaaagaa gatgtagcaa ttactctgat cgatcgtcat tcgtaccata
     3661 ctatgatgac cgagttgcat gaagtagctg gcggacgtgt agaaccagaa gcaatccaat
     3721 acgatctgca gcatttgttt gctcgtcaaa agaatgtaca acttgtcaca gacactgtaa
     3781 tcggtatcga taaagaacga aaaatcgtca agaccaaatt aggttcctat ccttttgatc
     3841 agctgatcct tggaatgggc ggagagccga atgactttgg tacacctggt gtcaaagcac
     3901 acggattcac cctttggtca tttgaagatt ctgtaaggat tcgggaacat attgagaaga
     3961 cagtagcaaa agctgcattg gaaccagatg atgaactgcg taaagccatg ctgactttcg
     4021 ttgtctgtgg ttctggattt accggtattg aaatgattgg ggaactgatc gactggaaaa
     4081 atcgcctagc caaagattat aaattagatc caaacgaaat cacactgatg gtcgtagagg
     4141 caatgccgac gatcttgaat atgttggatc gaaatgatgc tgcaaaagct gaacgctatt
     4201 tgcgtaagca caacgtggaa ttattattga atgcaccaat cgtagaagtg gctgctgatc
     4261 atatcaaatt gaaagacgga cgcaacattc cgactcacac actgatttgg acagctggtg
     4321 tcaaaggaac ttctgacgct gctgactttg gattagaatc agcacgcgga cagcggttga
     4381 tcgccaatga atatatgcag gcaaaaggct acgaagataa aaacatctat atcattggtg
     4441 atttagtctt ttatgaagaa ttcccaggaa caccgacacc gcagatcgtt caagctgctg
     4501 aacaaacagg acacacagcc gcagcgaata tcgtggcttc gatcaaaggc ggagaaaagc
     4561 ataaatttaa aggaaactat caaggattta tggtttctat tggtgccaaa tggggggtag
     4621 ctaacctatt tgataagatc catttaagcg gatttttagc tatcgtaatg aaacatatcg
     4681 tgaatttgaa atacttcttt gatattcgtt ctggttatta tatgttccaa tatttaatgc
     4741 atgagttttt ccatatcaaa gatgatcgca acgtgactcg aggacattct tctcgttacg
     4801 gcaatgtctt atggagtgtg ccacttcgta ttttctatgg tttagtttgg ttcgttgaag
     4861 cttccaaaaa aatcattggg aatggtgaag tgttcaaacc aagtacttgg tttggtgaag
     4921 gatcatggtt cactggaaac agtgtgttcc cttggacatg ggaatacaat gtaacagatg
     4981 ttgccagtgg tgcttctgct gctggtgatg caaccacagc tgccagcgga gcaggggcaa
     5041 gtgccggaga agcagcgact caagctgcac attttggttt gagttatgca tacggtgaag
     5101 aaccaatggc tgtgattgag aagtcaccag actggttcac aaagatcatg caagtgatca
     5161 tgccaaacaa tgatgtagca atgttcttcc aaaaattcat ggtattcttt gaaattgcct
     5221 tggcattagc attgattgct ggattattca catggctatg cagtgcgaca acgattgtat
     5281 tggtgatcac gttctgctta tcaggcatgt tttactgggt aaacatttgg ttcatttttg
     5341 ttgctttcgc attgatgaac ggttccggac gtgcgattgg gttggatcgc tgggtaattc
     5401 catggctaca acgtacacta ggtaattggt ggtacggtag accaagttcc cagtacggca
     5461 agaaataaat agataaagaa cgttatttga atgcaagatt tcaatagaaa ggggctgaga
     5521 caaaccgtca cagcctcctt tt
//
LOCUS       DACGLI010000101         5480 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.108, whole genome shotgun sequence.
ACCESSION   DACGLI010000101 DACGLI010000000
VERSION     DACGLI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.108"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..1389
                     /gene="gadC"
                     /locus_tag="IXT22_002746"
     CDS             <1..1389
                     /gene="gadC"
                     /locus_tag="IXT22_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HAQ4864059.1"
                     /translation="GGILWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAI
                     FFQWFQITVGFITMIYFILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTN
                     RTAKIAKAGFVIGIVIPSIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFV
                     SFILAYMGVEASASHINELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLS
                     LSAGVIQTFETLILHFNSHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGL
                     LPVFFRKTNKQDVPVPLIMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGY
                     LLFFLGYFVLVFKKKDLKRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAAS
                     EHRTYQIILLISFVVTVLLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEH
                     HVTKNDEHILKH"
     gene            1402..2802
                     /locus_tag="IXT22_002747"
     CDS             1402..2802
                     /locus_tag="IXT22_002747"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003134257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAQ4864060.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(2967..4402)
                     /locus_tag="IXT22_002748"
                     /pseudo
     CDS             complement(2967..4402)
                     /locus_tag="IXT22_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            4795..5388
                     /locus_tag="IXT22_002749"
     CDS             4795..5388
                     /locus_tag="IXT22_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HAQ4864061.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
BASE COUNT         1728 a          906 c         1057 g         1789 t
ORIGIN      
        1 ggaggtattt tatggtttct accagttgct ttatgtgctg cagaaatggc aacagttgaa
       61 ggatggaaag atggtgggat tttcagttgg gttagtcaaa ctttaggaga acgttttggt
      121 tttgcagcta tttttttcca atggtttcaa attacagtag gttttattac aatgatctac
      181 ttcatactag gagcgctgtc gtatgtaatt aattttccag agcttaatac agatccattt
      241 atcaagttta ttggtgtatt agtcattttc tgggtactga ctttttcaca gttgggcggg
      301 accaatcgta ccgctaaaat tgctaaagca ggatttgtca ttggaattgt tattccttcg
      361 atcattctct ttggtttagc agcagcctac tttatcggcg gtaatccgat tcaaatggct
      421 attaatgcga aagcttttat tcctgacttt tctcagcttt caactttagt agtatttgta
      481 tcttttatat tggcttatat gggcgtagaa gcttcagcat cacatattaa tgagctggaa
      541 aatccccaaa gaaactaccc attggcaatg tttttactag tgattttggc catcgcctta
      601 gatgcaatcg gcggtttctc agtagcagcg gttattccac aacatgactt gtctctcagt
      661 gctggtgtaa tccaaacatt tgaaacgctt attttacatt ttaacagtca tttacattgg
      721 ttggtaaaag tgattgctct catgattgcc tgtggcgtta tgggtgaagt tagttcttgg
      781 gtagttggtc catcacgagg gatgtttgca gctgctcagc gaggtctgtt accagttttc
      841 ttccggaaaa ctaataaaca agacgttcca gttccgttga ttatgataca aggaattatc
      901 gttactattt gggcagcagt cttaactttt ggtggaggag gcaacaattt atcattctta
      961 gtagcaatct ccttaactgt tgtcatttat ctcgtaggat atttactatt tttcctaggt
     1021 tactttgtat tagtttttaa gaaaaaagac ttaaaacgaa cttacaatgt accaggaaaa
     1081 actgttggca aaacgattat cggtggaatt ggttttattt tatcagtgtt cgcattgctt
     1141 atctcttttg taccaccagc ttcaattgca gctagtgagc accgaacata ccaaatcata
     1201 ctacttatta gctttgtagt gactgttctt ttacctttta tcatttatga agtacatgat
     1261 aaaagtgctc acacaactat tgaggaacct actcacgtga aagctgaaga cgttaatccc
     1321 gctgtttatc cagctgctag aggagagcac cacgttacaa aaaatgatga acatatttta
     1381 aaacattagg aggaattcat tatgttatac ggaaaagata atcaagaaga aaaaaactat
     1441 ttggaaccaa tttttggctc tgcaagtgag gatgttgact tgcctaaata taagttaaac
     1501 aaagaatcca ttgaaccacg aattgcttat caattagtac aagacgagat gttggatgaa
     1561 ggaaatgcgc gattaaactt agctactttt tgtcaaacgt atatggaacc tgaagcagtg
     1621 aaattgatga cccaaacgtt agaaaaaaat gcaattgata aatcagaata cccacgaaca
     1681 acggaaattg aaaaccgctg tgtaaatatg attgctgatt tatggcatgc tccaaataat
     1741 gaaaaattca tgggaacttc aacgatcggc tcttcagaag cctgcatgct gggtggtatg
     1801 gccatgaaat ttgcttggcg taaacgtgct gaaaaattag gtcttgatat tcaagcaaaa
     1861 aaacctaacc tggtgatctc ttctggttac caagtttgtt gggaaaaatt ctgtgtatat
     1921 tgggatgtgg aactgagaga agtcccaatg gatgaaaaac atatgtcaat taatctagat
     1981 actgtcatgg attatgtgga tgagtacaca attggtattg taggtattat gggtattact
     2041 tacactggtc gttatgatga tatcaagggt ctgaatgatt tagttgaagc tcacaataaa
     2101 caaactgact ataaagtata cattcatgtt gacgctgcat cgggtggctt ttatgcacca
     2161 tttactgaac ctgatctagt ttgggatttt caattgaaaa atgttatctc aattaattct
     2221 tcaggtcaca aatatggttt ggtatatcca ggtgtgggtt gggtcttatg gcgtgaccaa
     2281 caatacttac cagaagaatt agtatttaaa gttagttact taggtggaga aatgccaact
     2341 atggctatca acttctctca tagtgcagca caactaattg ggcaatacta caactttgta
     2401 cgctatggct ttgatggtta tcgtgatatt caccaaagaa ctcatgatgt tgctgtttat
     2461 ttagccaaag agatcgaaaa aactggtatt tttgaaatca ttaatgatgg atcagaattg
     2521 ccagttgtgt gctataagct gaaagaagat cccaatcgcg aatggacact atatgattta
     2581 tctgatcgtc tgttaatgaa gggatggcaa gtcccagcct acccattacc taaagacttg
     2641 gatcaattaa ttattcaacg cttagttgtt cgagcagact ttggaatgaa catggctggt
     2701 gattatgtac aagatatgaa ccaagcaatt gaagagttga ataaagctca tattgtttat
     2761 cataaaaaac aggatgtgaa aacgtacggc tttactcact aaaattcttc agagaaatat
     2821 aaaagaagtt aattaactaa taaaaggagt tgtgattacc acacagctcc ttaaatctat
     2881 ttgaataaat atatgatatt catttgttac actctcaatc ttagctgttg ttctattcat
     2941 cattactctt attgtaagta gttcagtcaa atttgcttgt tcaattgatc gataacagta
     3001 tgaattgttt gaaaagtaat cggatatata attgttttct cactacctaa gccttcttgg
     3061 tataaagaac tatcgcaaag tataatccgc tgagtacaaa agaaagtgtc gtctactatt
     3121 tctctaagtt gtttacaaat gatattacta atagaaaagt gttctcccaa aatgtcttct
     3181 aactgttgtc gatagtataa atacctaaag tctgacggag ctactatgaa cacttcaatt
     3241 ggagatttcc gtttatgctc atttaaaaga cttaaactaa tggttagttt acgaatagaa
     3301 ttctcattcc aacgcagaaa taaattgttt tgttttcgcc attgttcaag aatttcatga
     3361 acttctaagt acaaagcgcg ttgctcttca tttaacaagt aagtcttatc aggttgaaat
     3421 atctgaatat cagcccaaag tgagcggata aacgggagaa gtgctttatc aaaaagtatc
     3481 tgattttctt cagatatatt cagagataag ataagttttt gactgagctc aatcaccaaa
     3541 gggttatctg ctacatggtt ttgataaaca acgttcaagt ctttttgtaa caattcaaag
     3601 ttatcgcata gataatttct agagttgaat agaaagtaga tataaaggca ttcatcttcg
     3661 tcatgacata aagagaaaga aagttgctct aatcctttct gtattagctg aaacaaggga
     3721 gtatgtcggg caactctttt ttcttcctga ctaaaatata ttgggttagt cttagatctc
     3781 tgcaaaccga tagcgatacc taataaaata aattgttttt caactgtagg gtaacttctt
     3841 gaaaaaaatg tttttctaca taatcaatca attgttgacc gctttgaata attgatttat
     3901 ttagctggat caactctgtc cgatttgtct catagattat cgttagtaac aaacttcgat
     3961 aatccttttc aggaatttca aaatggccat cagcatttaa gtactgcatt tgtttaaaaa
     4021 aattaatcaa ctcatttcgt aagttgtaaa ctttgcttaa cgaaatgaag gtagtatcag
     4081 ctatattact ccaattgtgt tcccctgata aataatgtcc tagtacattg aaaaagtcag
     4141 agcgctgata gatgagttga gtgagtgcca acctcgaaaa cgaagagtcg aatgcgactg
     4201 taaagctact tctagatttc tccactgaaa taatttgctg atggagtatg tcggtaatgc
     4261 attccaagtc gttagtgaca gtgagtgggc aaacgttcaa ttgatctgct atttcgcgaa
     4321 tctgaatggt ccctttttcg tgtaattgct cacaaatgta aacttgacga aaaatacttt
     4381 tctccagata ggtttccaac atagtactcc tcctagtcat tttatacata actattataa
     4441 ctctaccaat cggaatagtc ctgtaatata ttgaatcaaa aatataaatt ataaaataat
     4501 tagatggggt atttggttta agtatccctt atatagtaat aaatttatag gtgtgattct
     4561 cgaattaata cccgaaaatg tgagagaatt tttatggatt ttttaggata caaattaatt
     4621 atttttgctt ttatcctgat taccagtcca gtactgtcgg tatcccattt tgcagcaaaa
     4681 tcatgttgat aaagtgacaa gaagactgat gagatatatt atccaaattg agaagataat
     4741 taatcggatt cttgagtata ccctactttt taagaaagta gggtatacaa gcgtatgaat
     4801 aaagacataa ctttccctgt gatggacgtt cggcttgttc caattaccaa aatacaggcg
     4861 aacgattata atcccaatcg agtagcgtct ccggaaatga acttattgga gctttctatc
     4921 attgaagatg gctttactca accattagtt tgttattaca aggaaaaaga agagaagtat
     4981 atcttggttg atgtgcttca taggtatcgt gttgctaagg aaagactcaa cttaaaagtt
     5041 gtaccggtaa cagttattga taaacccata gaagaacgta tggcttcaac aattcgacac
     5101 aatcgtgcaa gagggaccca tgaaataaga ggaatggaaa ttgtcatcca aagattagta
     5161 aaaaatggat ggtcagacaa gagaatatcc aaagaattag gcatggacat tgaagaaatt
     5221 tttcgcttta agcaagtgtc tggtggaatg gcaacagttt ttttgacaaa ttttataagg
     5281 tgcagaactt ctttccgtat gctattccga ttgtccttga caatgagcct cctcggatgt
     5341 gacgatcttc ggcaggagct aacagttaaa gttagactgc ctcgctagcg ttagcacatc
     5401 cgagctcatt atcaaggatt cgctgcgcca atctctggtt acggtaacca accggtgtct
     5461 cgtagccaag tgtaccgtgc
//
LOCUS       DACGLI010000102         5424 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.109, whole genome shotgun sequence.
ACCESSION   DACGLI010000102 DACGLI010000000
VERSION     DACGLI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.109"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            231..1205
                     /locus_tag="IXT22_002750"
     CDS             231..1205
                     /locus_tag="IXT22_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4864062.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1187..1648
                     /locus_tag="IXT22_002751"
     CDS             1187..1648
                     /locus_tag="IXT22_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4864063.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1698..2162
                     /locus_tag="IXT22_002752"
     CDS             1698..2162
                     /locus_tag="IXT22_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4864064.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2176..2925
                     /locus_tag="IXT22_002753"
     CDS             2176..2925
                     /locus_tag="IXT22_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4864065.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2925..3755
                     /locus_tag="IXT22_002754"
     CDS             2925..3755
                     /locus_tag="IXT22_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4864066.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3755..4402
                     /locus_tag="IXT22_002755"
     CDS             3755..4402
                     /locus_tag="IXT22_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4864067.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4500..5276)
                     /locus_tag="IXT22_002756"
     CDS             complement(4500..5276)
                     /locus_tag="IXT22_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4864068.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
BASE COUNT         1858 a          742 c          971 g         1853 t
ORIGIN      
        1 atcatagcta tcactccttg cattcgtttt cataaatcta ttataaaaga aaagactgta
       61 gacatcatcc ataaaatgga ctttgtctac agtctggcat tttattatat aaaattgtta
      121 taaaaaaatt tttttgaaaa atagtattgc aaaataaagc aatttcatag ataataggta
      181 ttgtaaagtt atatgacttt ataatactta ttagagtgag ggataaagaa atgagacaac
      241 tacacaaaga acagattgaa acagcaatgg cagcgttaaa ggaaaagaca attgatcatg
      301 tatattttac agcatgtggg ggttcacaag ccgttttaat ggctggtcaa tatctatttg
      361 ataaagaatt aactgtacct tgtcatgttt atactgctaa cgaatttaac tatgctatac
      421 caaaaggatt atctgaaaat tctttagtta tcacttgttc ccattctggc acaacaccag
      481 aaactgtaga agcaacaaaa aaagcaagag aatttggagc aatgactatt tgtttatcta
      541 atgaagaagg atctcctcta tgggaagcag ctgaatatcc tgttcactat gattggggta
      601 aagatgttga tgctagtgat ttaaataaag gaattcttta tggtttatta tttaatattt
      661 tacttgtttt agatggctct aaaaaatggg aaacttgctt gaatgaattt gataagttaa
      721 atgatcttgt tattgctgaa aagagcaaat ttgaaataac tgctaaagaa tggggtaaaa
      781 accaaaaacg agataaaatt atttacacaa ttggtagcgg tatcaattac ggagaaattt
      841 actccacagc agcttgctgg ttcatggaaa tgcaatggat taattctaat gctattcatt
      901 ctggggaatt tttccatggt ccttttgaaa tcactgatta tgatgtacca ttcatcttag
      961 tgaaaagtat tggagataca agatttttag atcaacgggt agaagacttc actaaaaaat
     1021 tcagtaataa attaatggtt ttagaccaag ctgattttga cttagaatct atagatagtg
     1081 tagcgaaaga atatattgca gctgtactta gtggcgttgt tattcgccaa atggtagaag
     1141 cgattgcttt tgaaagaggc cattccttag atgttagacg ctatatgtgg caaatgaaat
     1201 attaattaat aggaggttgc aaaagatggc aaatcaatta tttcacattg tgattacaac
     1261 acattctacc ctttgtgagg gttatttaaa ggcaacaaaa ttaattttaa tgaatgacgc
     1321 cacaggtatt agtgctgttc catttaaaga aaatactagt ccagatgatt ttgaggagag
     1381 tatgaaagaa ataattagtc agcatcattt gcaacctcta attattttaa cggatttaat
     1441 tggaggaaca cctaataatg tttctattaa acagttgaac aacaatagaa ttcaaattat
     1501 tgctgggatt aatttacctc ttttactgga gttattaatg gcccagtcag ctggtaaatc
     1561 tatagaagaa atagatttta aggaattact gaataactct caaaaaagta tggttcatat
     1621 taattcgctt ttaaaagatg tcagttaagg tggcaatttc tattctataa attttaaaaa
     1681 ttgaaggagg aaatagaatg attaaattag tgcgtgtaga ccacagatta cttcatggac
     1741 aagtaatatt ttcttggact aaacagtatg atattaacca tattattgtg gctgataaca
     1801 aagttccagg agatccaatg tctgtgatgg ctttgacaat tgctaaacct gctgattgca
     1861 aattagacat tgttaaaatt agtgatgtta aagggattat ggaaacatcc ccaaatgata
     1921 attacatgat tttaattaaa ggacctaagg aagcttttga attagttcaa aatttaccag
     1981 aaattaaaga aattaatttt ggcggtgtgt ctaagaaaag cgagtccaaa caatatggaa
     2041 aggcagtctt tttaactcct gaagaattag aagccacaaa aaaaattctt gatcaagaag
     2101 tgaaaatatt tgtgcaacaa gtcccatctt caagtattga aaatgtagat tttagtaagt
     2161 aaggggggaa aataaatgtt attaaaagcc attttattag gtttagttgg tgtggtagct
     2221 gttattgact ccaggttaat tggtcgacaa aatattggta gaccactaat tttgagtaca
     2281 cttgccggac ttgtgctagg tgacttgcat acagggattg ttcttggggc atctttagaa
     2341 ttaatttcta tgggattcgt ctcaattggg gcggctggac ctcctaatat gcaacttggt
     2401 agtattattg ccactgcttt tgcaatttta actaatagta gtacagaaac agccttaaca
     2461 atagctatcc cagtggctgt agctggtgaa tttatgagta ttatcatgcg catgataatt
     2521 gctcaatttg gacatgctgc agataaagcc attgaaaata ataaatttag aaaagctcaa
     2581 attattcata tttattggtc atttattttt aatgcttttg tttactttat tccaatcttt
     2641 ttaacagtat attttggtgc tgacgttgtg gcagatttag tagataaaat tccagaaatg
     2701 attacagacg ccttgactgt ctctggaaat atgctttccg cattagggtt tgcaatgcta
     2761 ttaagcacaa tgttgagtaa aaaattatat ccttacttta tttttggatt ctttattgtt
     2821 gcctattcag gtctttcact aattggcgtg acaatttttg cagctctgat tgcctttgta
     2881 atggatcaag ttaaatatgg aaaaagagaa gaggcgcatg gttaatggaa aatagtacag
     2941 aaaaaaaacg tttaatcaca aaaaaagatc ttaataagat gtgtcttcgt tcatggacaa
     3001 tcatgtgttc gtggaattat gaaagacaaa tgcatatggg atttatgtat gggatggcgc
     3061 caattttaaa taaagtttat aaaaatgatg aagagaaaaa aagagaagct tatactcgtc
     3121 atatggcatt ttttaactgt acgcctcaaa tgacttcatt tattatggga ctttgtgctt
     3181 ctatggaaga acaaaatgct caagcagaag aaggaaactt taatactgaa tctatctcca
     3241 tgattaaaac cagtttaatg ggtccttttg ctggaattgg tgattcattt ttccaaggta
     3301 ctttaagaat tattacattt gggattggat tgtcttttgc taagcaaggt agtattttag
     3361 gaccgatttt agctgttggc ctttttgcta taccttctat tttagctgtt ttttacggcg
     3421 gtaaattagg atatgagtct ggcaataaat accttactaa attgtatcaa gaaggtctta
     3481 tggatcgagt aatgcaattt gcttctatca ttggtttggc tgtagtaggt ggaatggtgg
     3541 ctagcatggt gccaattgtc acccctttaa aattcactac agggggaaca gaacttgttt
     3601 tacaagactt acttgattcc attattcctg gattattacc acttgtatgt actttgggaa
     3661 tatataaatt gattaagaaa aatgttagta caaatatgct cttattaggt tgtattttgg
     3721 cagggtttgt tttaagtata ataggtatct tataatgatt aaggctctaa tttttgatat
     3781 ggacggagtt ttaattgata gcgagattat gtatcaaaag tgggtattta attttttaaa
     3841 acaagaaaat ttaagctatc ctttgtattc ttatcaaaaa aagattggaa ctacagcaag
     3901 tatttttgat gatatagaaa agtacaatga gggatgtaac agtttagaat tgaagggaaa
     3961 atttactaaa tattggaaat cgcaaaagat tgattacttg gatatttttc ctaatatact
     4021 aattgaacag cttgaatggt taaaaaagaa aaaaataaaa atggcaattg cttcttccag
     4081 tccaatggat actataaatg aagttgttac cacttgtaaa atagagtcat attttgattg
     4141 tttaattagc ggaagagatt tgccagaaag taaacctaat cctactatat tccttaaagc
     4201 ttcagaacag ctcagaattc cagttgaaga atgtctggtg atagaagatt cttataatgg
     4261 tataaaagct ggtaaaagag caaatatgaa ggttcttgca attaaagata aacgtttttc
     4321 tcaagatgta agtctagcag atgatgttat ttacgatatt aaatatctgc gacaagaagt
     4381 acaggtgaaa tttggaatat aaataagttt tttgatgtat ttagagaata ttagtaaaaa
     4441 taaaaatcat gcccaaatct aatcaaaatt gattgctttg ggtatgattt cttttaatat
     4501 caatctatta ctttaggatc tgaatcattt ttatgcaccg tatctaaagt gatattttct
     4561 gtgacttcaa taacataact aattctatca caacgaactg tggattgaga ataatgaaat
     4621 ggttgattat ttttatcttt gccaaccttt tctaaaataa atagcggatc tcctactata
     4681 cattgcaata agtcggaaag ctcaggtgtt gcagataaac cgtttatttc cataatagag
     4741 ctcgtagctt tgacatcata gtcatcttct agaagtttat ataatgaagt atattggcta
     4801 cctttttcaa ataaagttgg aaatttttct tctgatgcga aaaaattatc aattcccatc
     4861 ggggcaccgt cttcccacat taaacgttta atattgtaaa ctctatcagt tacattgatt
     4921 tgtaatttat tagctaaaaa ctcatcagcc tttataattt tagaatgtaa aacagtatat
     4981 ctaattttat gtcctcgggt agaaagagaa tcgctaaatc catgaactcc agctaatttt
     5041 aaactttctt ttttttgagt tacaaaggtc cctttccccc ttaatcgttc aactgttcca
     5101 ctttctgcta aaagtttaaa agcttttcga atggtaatct tacttactcc ataaatttta
     5161 cataattctt cttctgtagg taattgctct cctggaagat attttttttc acgaatatcg
     5221 ttacgtatag aagcttctac ttgtaaatat aatggtctat tatcttgaaa attcatagta
     5281 cactccctaa aaagttatac ttcattatat cacaatttat taaaacgtcg attgtaaaat
     5341 taagctagac aactaaaaag atcatttgtg ctacactcaa aatagttccg accaaagaat
     5401 taataaggag tgagtacaaa tgac
//
LOCUS       DACGLI010000103         5337 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.110, whole genome shotgun sequence.
ACCESSION   DACGLI010000103 DACGLI010000000
VERSION     DACGLI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.110"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(61..279)
                     /locus_tag="IXT22_002757"
                     /pseudo
     CDS             complement(61..279)
                     /locus_tag="IXT22_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(545..739)
                     /locus_tag="IXT22_002758"
     CDS             complement(545..739)
                     /locus_tag="IXT22_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864069.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            2091..3131
                     /locus_tag="IXT22_002759"
     CDS             2091..3131
                     /locus_tag="IXT22_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAQ4864070.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            3955..4287
                     /locus_tag="IXT22_002760"
     CDS             3955..4287
                     /locus_tag="IXT22_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAQ4864071.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4903..5244
                     /locus_tag="IXT22_002761"
     CDS             4903..5244
                     /locus_tag="IXT22_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAQ4864072.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1942 a          727 c          900 g         1768 t
ORIGIN      
        1 aggtattttt attatatata gatttaacat atgtcggtcg gttgattgat atagctaaag
       61 ttataactca accgaagccg attcatctac acgaataaag ttgcgagtgt tctcggctaa
      121 ttcataaaaa ttgttatgtg ttccatatag caatactgga ataactttat tttcttgaat
      181 ctcataagca actctataca cggtgaccgc atacttaaat ccattagacc aattacctga
      241 taaacctcca gttttttgct cttacttaaa tggatcaatg gcaatttcat cacaaaccta
      301 tagaggatga gtgacttctg cctaattacg ttaaaaaata ttgaaagtaa ctctatgtag
      361 caaaaaatat ctagaatttc atttcctcaa aactgatcga tattgtatct aaaaatatat
      421 actacctaaa ataggtagta tatattaaaa tatgtgcttt tgttagaaaa atcaatacat
      481 aaattatcat atctgtatat gtcatttagg tatttcagtt atgttataat agttttgctg
      541 tctgctaccc cggcctaatc tggcaagggg aggaggagat ataatgaaat acctttttga
      601 ttttgttttt gcaatcaagc cacttgcaga tgtagtgtgc agttacctct gcaaatggct
      661 tgattgcaaa attgccaaaa aagacagtaa gcctacccgt taattctata atatagaaac
      721 gtaaaaaaaa ccccatcagc ctgcacgctg atggggtttg gtgatataat gaaatacctc
      781 tttgttactc ataattatac cataattagt cacgaatgca accaatagaa aaaactactt
      841 agaacggtag atcatcgcta ataacaatgc attgtccacc aaatggattt tgtgaagcat
      901 taaatacatt gttattaatt gtcgctgctt ttaactaggc ctctcccctt ctattataaa
      961 agaagatata tatcatttct taattaccta ctaccttaaa ccaaaattta agtactacct
     1021 aatttaagta gtacttaaac aatctaaaaa atagttatcc caattgttat gcttttataa
     1081 tacgattatt tgtaacaaaa tgaatattat ataattaaac actaccatat ttaggtagtg
     1141 tttaattatt agcaaaacaa aaaatattta ttctattctc ttaacttcaa ctaagttatg
     1201 ctgcacacct ttatataaat catatgcaac tcattagcta gacaaactac aagcatgtag
     1261 ttttatctgt taattatgta ctacctaaat aaagtagttt ataattagca agtatatata
     1321 tttaaaaatt taagattaat ttttttatga cttgtacaaa tttatctgat attctcttat
     1381 taagaactac ctaatttggg tagttcttat tttttacatt ttaagtagta tttaattgca
     1441 atttggtagt atttttttat tatcttattc ttagaacggt agtacttaat ataaatatag
     1501 gtagtatcta atttaagtat taatggtagt atctaaatta acaggtagta tgtaactact
     1561 ttaaagtaat ttttttcaga ttaacacagt agtatcttat taaataagtt aattttaatg
     1621 gtagtacata attattatat atatctgaca ttggtagtac ttattgtatt ttttagtagt
     1681 atataatcta ttgttttcta gcctaaagcc ttgtcttata agaataatat aatatatact
     1741 actgaaataa ggtagtatat attactagta atggtagtat gttttatatg cataaggtag
     1801 ttcttaattt attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact
     1861 aaattttatt catacgtttt tctggtagta tttaattata aataatattt atttaaagta
     1921 gttcttaatg actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt
     1981 taattaaaaa acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa
     2041 gagtaggtaa ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt
     2101 ttaaattttt taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct
     2161 ttattgtttc tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt
     2221 taaaagcaag attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt
     2281 attttactta tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga
     2341 tagcaatcaa aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta
     2401 acaaacagtt agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag
     2461 aaaatgatat ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat
     2521 cagagggtat gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg
     2581 ctcaagaggg tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa
     2641 tcataccaga acttaataat aatatattag acactaatag acacaatata gacactgaaa
     2701 aagaccgcct acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca
     2761 gcattgctac gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt
     2821 acagtgaagc tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag
     2881 aaagtgatat ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag
     2941 aattatacac gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata
     3001 tccagaacct gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta
     3061 aagtatcaag tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact
     3121 ggttagagtg aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta
     3181 aaaatttttt attattctaa ttatattacg aatattacaa aataatagct attttaatag
     3241 aatttataag ttaaaatatt atgataaaaa tcacaaacgt agccttttac gtcataagtg
     3301 ttaaaagaaa taattaattt caaatataga aaagggaacg tatgtttgca tactcctttt
     3361 ttttgagtta taataatacg cgaagagaga taatttcatt atttaaacaa gctaaaaatc
     3421 ttgatattac ttcttttcag gcaatacgaa tattattcgc ttacattttt tgtataaatt
     3481 taattgtctg ctatgcttgt gatgaattga ttttcgtttt gcacttttgg atgataaatt
     3541 tggacaattg aaaatacaaa aaaaagaaag gcggtatgaa ctcggaaggc tggtaacctt
     3601 cgtcagcgtt catacacggc attaagattt ggcccttaat gcgttaacct ttcagtgtta
     3661 cggtattacc cgcaatggat ttagtataac agatattcaa aagtgatacc actttttttg
     3721 gctgtgttaa ggttaaaaat acgtgatatt acgatgaatc tatgcctaag cataatgtta
     3781 taaaaatgtc cgtgtggctc tttgccgtat gacgaacgct gaaattagag ggaacgcatg
     3841 tttggatgcg ttccctcttt tttgtttgtc atgaacgaaa atcaattctc tatttttgaa
     3901 aaataacaag aaaaacttgt taaaaatatt taaagaaatt gggtggttta ttttatgtca
     3961 tatacaggaa ttttgagtct caaagatatt tgtcactacg gtaaacggtg taccgctaca
     4021 gagaaaatca cgaagaaact atcaactggc caaagtaaaa ccgttgtgca gtgtaagaaa
     4081 tatataatcc agaaagacaa agtctcagag gaaatgattt attacattgg gaaacaaaag
     4141 caaataattt taaaagatcc tatcccctta aaagagctat atccaacaat caaacatgtt
     4201 tatgaccaaa acggtgtact gattggtcga agaaaaaatg gagtcttgcg ttgtaccgca
     4261 aaagggatgg ggcgtttgat cggctgaatt gatcattctc ataacttgta ttttatcgtt
     4321 tttcgcttgc ttgaaaatat tgtcgagact tctaaaggaa cttagagtca ctagaaaaat
     4381 aaggagtaga cttgatctat caacaattcc cttcggggag tgacggggta ggttttaacg
     4441 attggtaacg taaaaaattg gtcaatcgag taaatgcgct tgtttggata gtggtgaaat
     4501 gaatttgtgt aaataataag cgcagagtaa acaagaggga atttagaagt tagacaagtt
     4561 agaatagcgt ctagattaat catgagcagc tactaaggga tctagacttt gacgcaaact
     4621 catggaataa ggagtaggtc ttctcgtaat ggggaggacg cacaagaaat tgtgtcgtgt
     4681 gctgcagtac atgtagatac ttgcgaggac gttgattatt ggatcaatcg agcatttacc
     4741 gctgtctagg gtttctcgtt tcggacgcca taaacgagtc gaaatttttt atgtattttt
     4801 aagtaaacga aaaacgataa aatatgaaca agtcctgaat aaagtgaaaa aattaatata
     4861 aagcatagag aaaatgaaat ttacgtaatg gaggaatgac aaatgaaaaa ttatgatccg
     4921 aatatacgat tgggcacaca tactattaag gtttctttcc aacgttggga ttacaaagga
     4981 tttgtgacgt ttagaagggg cggaaattgt aaaggattag atgttttagc attagacgag
     5041 gatgatttat acgatcaaac attgactgat aatccaattg gattcggctt gctacctgaa
     5101 gatgatgaag gtaatgaatg gtttaaaatg acgcttatga atgataatgg agacgaatta
     5161 tctgttgaag atacttggtc atatttgagt gattatattg tcagctttga aatcattgaa
     5221 tttgtagcgg ataaagaaga ataaaaactg gaggaataaa ttttacagat aaaggcttag
     5281 aaggagtcac gacgattaat aaaaaggtag tattacctta ggcattgagt aaggaat
//
LOCUS       DACGLI010000104         5250 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.111, whole genome shotgun sequence.
ACCESSION   DACGLI010000104 DACGLI010000000
VERSION     DACGLI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.111"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..556
                     /locus_tag="IXT22_002762"
     CDS             <1..556
                     /locus_tag="IXT22_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /protein_id="HAQ4864073.1"
                     /translation="NLIRGEFHFLSEKDMNIIPSFKDSGYIPDTKAMLIYDETGQLEN
                     YLSEISGARPNRLTEENANFLLCNFSNLWLMGINVLKRGEYARSLELLSQLQKNTLQL
                     IRMAEKNADNWLNMSKNLEKEISLENYKKFAKTTARLDKVELFEAYKNSLLLVMDLQS
                     HLIEQYNLKVTHDILERLLNYISE"
     gene            1244..2065
                     /locus_tag="IXT22_002763"
                     /pseudo
     CDS             1244..2065
                     /locus_tag="IXT22_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            2208..2432
                     /locus_tag="IXT22_002764"
     CDS             2208..2432
                     /locus_tag="IXT22_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864074.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGDEIKISNE"
     gene            2447..3316
                     /locus_tag="IXT22_002765"
     CDS             2447..3316
                     /locus_tag="IXT22_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAQ4864075.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3297..4031
                     /locus_tag="IXT22_002766"
     CDS             3297..4031
                     /locus_tag="IXT22_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4864076.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4064..4972
                     /locus_tag="IXT22_002767"
     CDS             4064..4972
                     /locus_tag="IXT22_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAQ4864077.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            4969..5217
                     /locus_tag="IXT22_002768"
     CDS             4969..5217
                     /locus_tag="IXT22_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HAQ4864078.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
BASE COUNT         1807 a          782 c         1125 g         1536 t
ORIGIN      
        1 taatcttata cgtggggaat ttcatttcct ttctgaaaaa gatatgaaca taatcccctc
       61 gtttaaagat tcaggttata ttcctgatac gaaggctatg cttatttacg atgaaacagg
      121 gcaattagaa aattatttat cagagataag tggtgcaaga ccaaatagac ttactgaaga
      181 aaatgctaat tttttgttgt gtaatttctc taatctatgg ttgatgggaa tcaacgttct
      241 aaaaagagga gaatatgctc gttcattaga actcttatca caacttcaaa aaaatacact
      301 acaacttata cgtatggcag aaaaaaatgc tgataattgg ctaaacatga gtaaaaacct
      361 tgaaaaagaa attagccttg aaaattataa aaaatttgca aagaccactg ctcgattaga
      421 taaggtagaa ttatttgaag cctataaaaa ttctttgcta ttagttatgg atttgcaaag
      481 tcaccttatt gaacaataca acttaaaagt tacacatgac attttagaaa gattgttgaa
      541 ttacattagt gaataggaga gtaacgttat tcacagtatt gggtactgaa aattaacagc
      601 atacctcagt ttttcaaaaa acagcgaagc ctatggatat gttcccgtct accgatagtg
      661 caaaaagtgt cgtggatatg tttccgagaa cggacataca caaatgacat tcattctgtc
      721 ctctcaatcc atgtggaagc agtatgtctg ttaacaagaa aataattatt gttcgtcctg
      781 acgagttgtt agactcgaaa aggataaaca tcatttttag aaccggtagc cgatttttgg
      841 ctagcggttt tttgggctct ttggcaaata gtggtgattg aatctcgcgc tatcctatgg
      901 aaaaccgcct tgtgtgaggg gctgcgagac cgcttcgatc ctagaattgc tgaagcacga
      961 atctagcgtc actcacattt catcttttga cgtagctgag acaaggtgtt tttcttcgat
     1021 ccgctagtgg ttaatctctt tttggtgcaa atatggttta gaatttcttt gcatggctta
     1081 agggagtgga gaatcggata ttagtaggat ttacatccac agataaaaat aggcttgatt
     1141 ttaacagcga aactaaaata ccctacttaa atgaagtgat agattagatg ttgggttgtt
     1201 aggagatgct taaaaatcct atgcaatcaa tagtttttag tgtttgttga cttgatccct
     1261 aaatcgcctg agtactaaac gttgagtgtg tctgcttact gtcactagcc agtaagtgag
     1321 actgtagtta atctctcatt ttccccagta ttatgttgaa aatagccatg aagcgattat
     1381 ttctaaagag ttatttttgc aggctcaaga agaaatttat cggagaagta atatctacac
     1441 aggagaaggc aagaacaaaa gaatttatag tagcaagtac gctttaagtg ccatcacctt
     1501 ctgtggatat tgtggcgata tttataggag aacctattgg aatattcatg gcagaaaaga
     1561 atttgtctgg cgatgcgtga ctagaatcga gcagggtccc gaggtatgta agaaccgaac
     1621 cgtaaaagaa gatgaactct atggtgcggt aatgaccgca attaataagc tacttgctgg
     1681 tggcaacaat atgataaaga cactggaaga aaatattcat gctgtgattg gagaaaccac
     1741 agaataccaa atttcagaga ttaataccct actagatgaa aaacaaaaag aactaatcaa
     1801 gctggccaat aaaggtcaag attatgaata cctggtagat gagatcgatg agatgcgaga
     1861 taagcgtcag actcttttag tagaagatgc ctccctcagt ggcgagaacg agcgcatcaa
     1921 tgagttgatt gaatttatcc gcaagaacaa attccgcacc ttagaatatg atgataagct
     1981 tgtaaggaag ataatccaga acgttaaggt ctatgaagac cacttcgtca tagccttcaa
     2041 accaggtatc gaaatggaaa tatgaaaacc agaagtaaat agcccatgac tctgaagtag
     2101 agttgtgggt tttcttttaa ttgctgatta taataatatt ttaatgacta ttgcatttat
     2161 caaccaaatg gtttatgtta ttcttagcat aaacttggag gtgctgtatg actacggcag
     2221 aaatgattaa agaactgtgt gagcaaatga atataagtgt ttccgaactt gctagacgta
     2281 ttggccagac tccacagaat tttaataaaa aattacaacg agaaacagta accttggatg
     2341 agttgaaggc cattgctgat gtgctaggtg tcaagtttgt gcaggcattt attttaccag
     2401 atggagatga aataaaaata tctaacgaat aaaggaggat gtttatatgg taggtaatgt
     2461 tattcaaata gtaacagaga aattatcatc tttgcctttt atagaaggca ttgtattagg
     2521 gggctcacgt gcaagaagca cccatacaga aaattctgat atagatatcg gaatctatta
     2581 caattcagac tcatttgacc tgacagcgat taatcaaatt gctacagagt tggatgatga
     2641 gaatagaaac aaccttgttg tacctcccgg agcgtggggt gattgggtta atggcggtgg
     2701 atggttagtt ataaacgggt gtcatgttga cttgatatta cgtgatataa aacgggtgga
     2761 acaaataatc aaagatacgg agcaaggaat tgttactgcc aattatcaga ccgggcatcc
     2821 ccatggttat ataagtgcta tgtatcgtgg agaattagcg attagtaaaa tactatatgc
     2881 taagaacgaa agcttatgcg aattaaaaaa gcaggcagaa atttacccta ctgctctaaa
     2941 gaaaagcttg atgaactttt ttatatttga agctgaattc tctttaatgt ttgtaaaagc
     3001 aaatgcgggg gcagaggata aatattatat tgcaggccat gtttttcgta ttatttcatg
     3061 cttaaatcaa gtactatttg catgtaataa tgcttattgc attaacgaaa agaaagctat
     3121 aaaactgctt gaaacttttg aatataaacc tgaaaaatat gccgaaagag ttaatcatat
     3181 ttttgaagta ctcggtcttt ctctttttga atgctacgac atgaccgaga aactttataa
     3241 agaagtgaat gaaattgtat cggagataaa taacttttta aacgaggaga gttcagatga
     3301 aagaaaacaa atatgatgat aatatatttt ttcaaaaata cagtcaaatg agtcgctcgc
     3361 agaaaggact ggctggtgcg ggagaatggg agactttgaa aaagatgcta cctgatttta
     3421 agggtaagcg tgtgcttgat ttaggatgcg gctatggatg gcactgtata tatgcgatgg
     3481 aaaacggtgc ttcctctgta gtaggtgttg atatttctca taaaatgctc gaagtagcaa
     3541 aaggaaaaac ccattttcca cagattgaat atgaatgctg tgccatagaa gatgtggatt
     3601 tcccagagga gagctttgat gtaatactaa gttcgcttgc gtttcattat gtagcagact
     3661 atgagaattt aataaaaaag atatatagga tgctgaaggc tggtggcaat ttagttttta
     3721 cagttgaaca tcctgttttt actgctcatg gaacacaaga ctggtattat aacgaaaaag
     3781 gagaaatact gcatttcccg gtggacaatt attattatga gggcaaacgg acagctatgt
     3841 ttttggaaga aaaggttaca aaatatcata gaacactgac cacatatcta aatacactgc
     3901 tttcaaatag ttttataata aatcagattg tggagccaca gccgccagag aacatgatgg
     3961 atattccggg gatggcggat gaaatgcgac gcccaatgat gctgattgta tcggcaaaaa
     4021 agaagatgta ataatataga aaaaataaac gaggagtatg taaatgagat cagaaaaaga
     4081 aatgatggat ttagtacttt ctttagcaga acaggatgaa cgtattcgaa ttgtgaccct
     4141 tgaggggtca cgcgcaaata ttaatatacc taaagatgaa tttcaggatt atgatattac
     4201 atattttgta agtgatatag aaccgtttat atctaatgat gactggctta atcaatttgg
     4261 gaatataata atgatgcaaa agccggagga tatggaatta ttcccacctg aagaaaaggg
     4321 attttcctat cttatgctat ttgatgatta caataaaatt gatcttacct tattgccctt
     4381 ggaagagtta gataattacc taaagggcga taaattaata aaggttctaa ttgataaaga
     4441 ttgtagaatt aaaagggaca tagttccgac tgatatagat tatcatgtaa gaaagccaag
     4501 cgcaagggag tatgatgatt gctgcaatga attttggaat gtaacacctt atgttattaa
     4561 aggattgtgc cgtaaggaaa ttttatttgc tattgatcat tttaatcaga ttgttcgcca
     4621 tgagctgctg agaatgatat catggaaggt cggcatcgaa acaggcttta aattaagtgt
     4681 aggcaagaac tataagttta ttgaaaggta tatatccgag gatttgtggg agaaactttt
     4741 gtccacctac cggatggatt cctatgaaaa catatgggaa gcattatttc tatgccatca
     4801 attgttcagg gcggtatccg gtgaggtggc ggaaaggctt cattatgcct atccggagta
     4861 tgataggaat ataacaaaat ataccaggga catgtataaa aaatacactg gtaaaaccgg
     4921 ctgcctggat agcacatatg ccgctgatat agaagagagg cgggaacagt gattacagaa
     4981 atgaaagcag ggcacctgaa agatatcgat aaacccagcg aaccatttga ggtgataggt
     5041 aagattatac cgaggtatga aaacgagaat tggaccttta cagaattact ctatgaagcg
     5101 ccatatttaa aaagctacca agacgaagag gatgaagagg atgaggaggc agattgcctt
     5161 gaatatattg acaatactga taagataata tatcttttaa cccgtggtgc tagttaattt
     5221 taatatccta aagaatatct caaagttcct
//
LOCUS       DACGLI010000105         5242 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.112, whole genome shotgun sequence.
ACCESSION   DACGLI010000105 DACGLI010000000
VERSION     DACGLI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.112"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(3..1151)
                     /gene="nagA"
                     /locus_tag="IXT22_002769"
     CDS             complement(3..1151)
                     /gene="nagA"
                     /locus_tag="IXT22_002769"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAQ4864079.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLTKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1227..2063)
                     /locus_tag="IXT22_002770"
     CDS             complement(1227..2063)
                     /locus_tag="IXT22_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864080.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2247..3464)
                     /locus_tag="IXT22_002771"
     CDS             complement(2247..3464)
                     /locus_tag="IXT22_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4864081.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3847..3930
                     /locus_tag="IXT22_002772"
     tRNA            3847..3930
                     /locus_tag="IXT22_002772"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3881..3883,aa:Leu,seq:gag)
     gene            complement(4170..5168)
                     /locus_tag="IXT22_002773"
     CDS             complement(4170..5168)
                     /locus_tag="IXT22_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864082.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1621 a         1073 c          832 g         1716 t
ORIGIN      
        1 tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt catatcaggg
       61 ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt atcatcgatt
      121 ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg tgttgctaat
      181 ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc agctaagttg
      241 ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc taaattgtaa
      301 tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac atgatcatgt
      361 cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc atcacaaatc
      421 aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg ttcgcgatga
      481 ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc ttcaacagct
      541 ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac tccttcttca
      601 gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc aatttttttg
      661 gttaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg atccccgaaa
      721 taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc aaaatagatt
      781 cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc agctacatct
      841 tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac tccacaagat
      901 aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac atcatgattc
      961 atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc gctttggtca
     1021 atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag tccatcggta
     1081 atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc agcatagata
     1141 aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc ttatttagag
     1201 aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt cacagcttgt
     1261 gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta tattaagctt
     1321 ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc ccaatagatt
     1381 ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa gaaatttcca
     1441 taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga ttgatgcagc
     1501 agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc cacaccatat
     1561 atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat tctttctttt
     1621 tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat attttgacgc
     1681 aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt tgcttgatac
     1741 agattttcag aaatatcaga agattttagt acttgttcta acttccgata atcacgtttt
     1801 tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt ttttcgagag
     1861 agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat catcaccaat
     1921 acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga acaaatatca
     1981 tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat gatcgttcca
     2041 aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt cgcattctat
     2101 tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta aataatatac
     2161 tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt ctgtggccct
     2221 cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag gaattctctc
     2281 attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat tcgaaaatga
     2341 tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg ttcatgtaaa
     2401 aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc aatttttggg
     2461 aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc attgattgca
     2521 ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag ctcatcgaca
     2581 ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt ggaacacaaa
     2641 cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga cttatctcca
     2701 cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga tagaccgttc
     2761 agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc tagaccatcc
     2821 atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg tcgagctact
     2881 tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt attaggatta
     2941 atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc aatatcagga
     3001 taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc taatgcaata
     3061 gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc attgtccagc
     3121 aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta gatatcattg
     3181 atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt tctagcagaa
     3241 aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat caaatcacga
     3301 atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt caattttaaa
     3361 atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc gcgaacatcg
     3421 taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta gccaatccct
     3481 catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa tatcatactc
     3541 catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa aacacaaaca
     3601 agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc aatccattgc
     3661 aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg caagtccaat
     3721 caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct ccatcttaat
     3781 aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt agtgtgttat
     3841 tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg tgagcgttag
     3901 ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat tttgcttcac
     3961 gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt atcctttaca
     4021 aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg gaaacaagct
     4081 actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa atccctcacc
     4141 taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat tataaaggta
     4201 caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac actcatgctt
     4261 ttcattagct ctttaactgc cattagtact aagatggcga taacaacata aagtatatag
     4321 tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa ccttgaacaa
     4381 aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc aaaacttaaa
     4441 taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc tatccaagta
     4501 cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt caggttacta
     4561 ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg acccattgta
     4621 ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat acgcacataa
     4681 tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa taaaaataag
     4741 atattcatat ctaaaaaaaa cggctttcca aatgatgaaa tacctaaatc taacttatta
     4801 agaaagttga aatttttata ttcaggaaac catttattaa tttcatgtgc agcacgtaat
     4861 gcattccctg gagttgtcaa agagaaaatt aattctgcta agcttattat tgaaaatact
     4921 gataacttat aattatatcg tccattgaca atcaaatata aactaactat acttgttaga
     4981 acaaaaaaac aggcgttgac ttgttcttga ttagttaaaa atatcaataa aggaatactt
     5041 acccaatata tttttctatt tatttcttct cctcttaaga gttgaaaaaa cggataaaaa
     5101 gttagtaaac taaatgctac tggccactga tagttcaagg tggttgctct ccaaccggtt
     5161 tcccccatta ctgtcaatgg tattaaacag tatatagagc aaaccaataa taaattttta
     5221 acatttattt tctcaaaaac at
//
LOCUS       DACGLI010000106         5052 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.113, whole genome shotgun sequence.
ACCESSION   DACGLI010000106 DACGLI010000000
VERSION     DACGLI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.113"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(139..1101)
                     /locus_tag="IXT22_002774"
     CDS             complement(139..1101)
                     /locus_tag="IXT22_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4864083.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1103..2542)
                     /locus_tag="IXT22_002775"
     CDS             complement(1103..2542)
                     /locus_tag="IXT22_002775"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAQ4864084.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2727..4673
                     /locus_tag="IXT22_002776"
     CDS             2727..4673
                     /locus_tag="IXT22_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAQ4864085.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4937..>5052
                     /locus_tag="IXT22_002777"
     CDS             4937..>5052
                     /locus_tag="IXT22_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010051189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4864086.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEET"
BASE COUNT         1637 a          845 c          829 g         1741 t
ORIGIN      
        1 ggatttctcc actccaaaaa agtctaactt ttgggggtca ctacaagttg acaactcctt
       61 tttgtttaca aatcaattgg atatctacaa attgtatttt ctaacgaatt ttatagacat
      121 taaaaaatta atttaacgtt aaatacttcc tccagaaagt attgagattg gtaaaatata
      181 atccttattt gtcttttcgc ctttaatttt tttcagaaga atatcaacaa taagacttgc
      241 aatttcatca attggttgtc ttattgttgt caattgtggg aaaaatttct caataaaaga
      301 ggtaccatcg tatccaataa tttttaaatc ttctgggata ttaagtttaa gttgatgagc
      361 aattttcata gtgagaatgg ctgttaaatc atcagaaaca aaaataccat ctggtttgtg
      421 atttataata gttgacttta tttccatttc acgacggata gtagacagat tattaggaat
      481 tttgaaaatt tttccatttg gattttgaaa agaaaaacct agtgcacgta attctgtggg
      541 agaatccgtg ttatcatttc ctgtaatcat aatggtattt tgacaaccat ttttttgtaa
      601 agtcttagct gcaagttttc ccccttcaaa gttatctgaa gaaacaatgg aaacattagg
      661 agctaaattt ctatcaaaag caacaatagg tgctctcaca cgctcataat cagcaattcc
      721 aagattatgg cttgatgaga ttatgccatc aacttggttg gcttcaagca tttcaatgta
      781 ttctctctct ttagcaggat cattttgact attgcaaata atcgttttat atccatgttt
      841 aaataactct atttcgagat actcaatgag ttcagagtaa aagatattac taatattagg
      901 aaaaataaga ccaataagct gaggtgactt tccttgaagt ccacgtgcta aattatttgg
      961 tttataacca agagttttca tagcttcatg aactttttgt tttgtttttt ctgataaata
     1021 tcccttatta ttaatgacgc gtgaaacggt tgttgggcta actccagcta attcagcgac
     1081 atcagttaat tttgctacca ttttaatatt ttaattcaaa gtattttcca gtaggttcgc
     1141 ctgatttgat ttgaatacca ttttggtgat tttcagggaa tacacgacta gtaaacactt
     1201 tttctccttt attaataaaa atctcaatga ttgagttatc tacaaaaatg ttagcagttg
     1261 tttctttagt atcaattgag cattcacgaa tcgtaccaaa gtcagtggca tattgaatgc
     1321 ctgctttgct gcgatctaaa ataatttttc cttctttggt atctacaatc aagctaagtc
     1381 catttccttt actatcagag aaaagaagta actccgattt ctgatttgga ggaaaagtta
     1441 gttcaagctc ataagtatta tttgtttctg cttttgctgt aaattgttca gaactagcac
     1501 gtaatgatgt aatagcttct actggatatt ggtaaagttt accatctttt attgaaagtt
     1561 cttttacaag actcattgct ccctgataat catacttatc agttggataa tcgatatcag
     1621 gtagtccaat ccaactgaca atcagagcac gaccatcagg agtattgaat ccttgagtcg
     1681 catacgcttc aaatccataa tcaagatttt gaatttctga agcgcccaca agttttactt
     1741 tttctatgtc aagcgattga cagatcttaa aagtattcgg atagatattc ccataattta
     1801 gctcagattt atccaaccct tgaggacaat aaatgagaac aggttttttg tctacaaata
     1861 ctagatttgg acactcaatc atgtattctg aaccagtgcc gccaaaatca aggttgccaa
     1921 cttcctccca tgtttccacg ttattgtcat ccgctttgta aagtttgata aagcctgatt
     1981 tttctaaatt ttgtgctcca acaatcgcat acaattgtcc ttcataatta aacatttgtg
     2041 gatcacgaaa atgatcagtt acatcagcag gtttatgaat aagaacattc tcacctttcg
     2101 taatgttgta gtctttatcc atccatgctc cgatttgaag tgtatcacgt tcccaatttt
     2161 catttcgaac gtttcctgta tagagtaaga atagattccc ctctatttca tatgcagaac
     2221 cggaataagc gccgtggcta tctcgttttg tgtctggaag aagttctgct cctgttacat
     2281 gaaaatgaac taaatcatct gattcattgt gtacccattc tttcaaccca tgagcagctc
     2341 caaatggcca attttgataa aaaagcgtat attttccgtt aaaaaaagaa aaaccattag
     2401 gatcgtttaa caatcctgtt ttaggttcga tatgatagct agcacgccaa ggtgatcgtt
     2461 ttacattatc cttaatttta tccatctcat ctttagtcca atcagaataa gcacgatatc
     2521 gtatttctcg aggtaagttc atattttact ccttcaattt atctttttac aactagtatg
     2581 gtaaacgttt tccgttgaaa aatcaatcat ttcatttaaa aaaataaact atatgacaaa
     2641 cgtttgacat atttttaaga tatgctaaaa taaatttgca tttcagtgaa ccgttttcac
     2701 gtaaaaataa aaaaggagtg attcgaatga attacagtaa agtagcttcc gacgtaatac
     2761 aagcggtcgg aaaagataac cttattgcag ctgcacactg cgctacacgt cttcgtctcg
     2821 tactaaaaga tgacacgaaa gtgaatcaaa aagctttaga cgaaaatcca gatgtgaaaa
     2881 gcacatttaa aattaatgga caatatcaag tgattatcgg tgcaggtgat gttaatttcg
     2941 tttatgacga acttatcaaa aaaactggac tttcggaaat ttcaacagat gatttaaaac
     3001 aaattgctag taaagataaa aaattcaacc ccattatggc attaattaaa ttattatcag
     3061 atatttttgt tccaattata cctgcccttg ttgcaggtgg tttattaatg gcattacaaa
     3121 actttttaac agctgctgga ctttttggac caaaatcaat tgaagaaatg tatcctgcga
     3181 ttgaaggtat ttcctcaatg atccaactga tgtccgctgc accattcatg ttcttaccaa
     3241 ttttagtagg tatttcagct gctaaacgtt ttggagcaaa ccaatttctt ggtgctgcaa
     3301 ttggtatgat catgacaaca ccagatcttg gtggctcaac tgaatattgg aatatttttg
     3361 gttatcatgt ttcacaaaca aactatgctt atcaagttat tccagtttta gcagctgttt
     3421 ggatattatc tatattagaa aaattctttc ataaaaaatt gccatcatct attgacttta
     3481 cattcacgcc attattatca gtaatgatta ctggattttt gactttcaca gttattggcc
     3541 ctgtaatgtt attgttgtct aatggaatta cagacattat tgtttggcta tataacacta
     3601 ctggatttat tggaatgggt atttttggag gaacatattc acttatagtc atgactggtt
     3661 tacatcaatc atttccagct attgaaactc aattactttc agcgtggaca aatggtatcg
     3721 gacatggaga ctttatcttt gtagttgcat ctatggcaaa cgttgctcaa ggtgctgcaa
     3781 catttgccat ttggttctta actaaaaatt ctaagacaaa aagtcttgct tcctctgcgg
     3841 gtgtctcagc acttcttgga attacagagc ctgccttgtt cggagttaac ttaaaatacc
     3901 gctttccatt cttttgtgct ttaattggtt caggaattgc tacagcagta gcaggattac
     3961 ttaaagtagt tgctgtttca cttggttcag caggtttctt gggatttctt tcaattaatg
     4021 caacatctat tccattttac gtattgtgtg aattgattag ctttgtagtt gcttttgcaa
     4081 ttacttactt ctacggtaaa acaaaagctg ctggtatctt taaagcagaa gaaattgctg
     4141 aacaaacacc agttaattct tcaaaagtag caacaacaga tccaatatct actgatgttg
     4201 aatcaacaca aacaaaagtt tcatcagaaa caattgttag tcccatttct ggtaaagtga
     4261 ttagtctttc ttcagtaaat gatccagtct tttcatcaga agctatggga aaagggattg
     4321 ccattaaacc aaatggaaac acggtccatt ctccagtaga tggtactatt caactcacgt
     4381 ttgaaactgg acatgcttat ggtattaaat caaataatgg tgctgaagtt ctaattcata
     4441 ttggtattga tactgtatca atgggaggaa aaggatttac acaaaaagtt actactaatc
     4501 aaaaagttag aaaaggcgat attcttggag catttgaccg ttcaatgatt gagaaagaag
     4561 gtcttgatga tacaacaatg attattgtga ccaatacttc ggattattca gaagtaaata
     4621 tagtagctga aaatacagtc actgagggta ctgatttact tgaaatcaaa taaatatatt
     4681 tccctgagta aagatggaat tttctttcca aaatcaaata atatagatta atcaaatatt
     4741 tgagaataac attttattta atcttttcat atatcaattg tatgaaaaat tattagaatt
     4801 ttaaaaaatg ataaaaattc aaaaagaaaa aatagtagtt atttacttgt catgttacta
     4861 aataaaaaaa taatttaaat atgatatata gtcatttatt tagtgatttc attctaaaat
     4921 aaagggagaa atgtctatgc tatacggtgc aattgaagca ggcggcacaa aatttgtgtg
     4981 tgccattggc gatgaagaaa tgacgatcaa ggaaagagtg agctttccga caacgacacc
     5041 tgaggaaaca at
//
LOCUS       DACGLI010000107         4742 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.114, whole genome shotgun sequence.
ACCESSION   DACGLI010000107 DACGLI010000000
VERSION     DACGLI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.114"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            23..694
                     /locus_tag="IXT22_002778"
     CDS             23..694
                     /locus_tag="IXT22_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4864087.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            753..1193
                     /locus_tag="IXT22_002779"
     CDS             753..1193
                     /locus_tag="IXT22_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864088.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1205..1873
                     /locus_tag="IXT22_002780"
     CDS             1205..1873
                     /locus_tag="IXT22_002780"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4864089.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1937..2560
                     /locus_tag="IXT22_002781"
     CDS             1937..2560
                     /locus_tag="IXT22_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAQ4864090.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2616..3002
                     /locus_tag="IXT22_002782"
     CDS             2616..3002
                     /locus_tag="IXT22_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAQ4864091.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3215..4606
                     /locus_tag="IXT22_002783"
     CDS             3215..4606
                     /locus_tag="IXT22_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAQ4864092.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1578 a          782 c         1011 g         1371 t
ORIGIN      
        1 tgatgaaaaa agggggagaa aaatgaattt tttagttgtt ttaaaagata ctctgattga
       61 gcgatctaca tttctatatg ttcaattgca ggaaaataaa acattgctgc atttttcacc
      121 agagttccat ctagaggggc taacattagg agaaatctat caagcagaag ggctgtcggc
      181 tgttttgcac ttttttaagg tagaattgga attaccagta aaagattata tcgagctttc
      241 tcttgaatct tgggatcgag cagtggttga actgtttcca gaaggtttaa tgatcgatac
      301 aaacgatggg aagatccatc tgactgcagc agaactgcaa aaacaaatgc gttatcaaat
      361 agatgacgaa aattcttttt ctatttttag acgtcagcaa aagattctaa aaagcttttt
      421 aaaagtgatc agtaaaaaac ggaatctgat caaaacgaca cagctgttga aaaaatatcc
      481 aggtctgctt cacacgtcta ttcaatttcc tcaattgatt acgatgatcc atcgttttat
      541 acgtatgcaa cagctaccat ctaagaagct gtttcttcca ttgacggaca catttcgagt
      601 agtcaacaga gaagataaaa agaaagtgat tgtgattgac tttaccagaa atcggaatgt
      661 ccttcaccaa gttgcaatgg aaaaggccaa ttaaggcttt ttctttttgg atttttttgt
      721 cataataaat attagatgat ggaggagata atatgatgca aacatggtta gaaaggctaa
      781 tacgatttca gcagaactat cacaaactta tgcagggaag atatgcgaaa tttgatcagt
      841 tgaatcgcgg tctattgatc gctgcgcttg tctttagttt gctaagtcgt tggttgccct
      901 atagaatcgg acaattgttg ttcatcgtct ttttcggatg gatgatattt cgtttcctat
      961 caaaaaaaat ctaccccaga ctaaatgaga atcaacgtta tttgaaatat cttgatagag
     1021 tcaaagaaaa atatcatcag ataaaaaaca aaaagcaagt caaaatggat cgaaaaagtt
     1081 atactttttt tgagtgcccg aattgtcatc aaaagcagcg tgcacctaaa ggaaaaggac
     1141 gaatacgtgt gacatgcaaa acatgtggta taaaattcga aacgaatgtt taagggagaa
     1201 aagaatgaaa ttagtattat tacgtcatgg cgaaagcgaa gcaaattttg aaaattactg
     1261 gacaggatgg ctagatgtcg ccttaacaga aaaaggaaaa gaacaagcag cagttgccgg
     1321 tcaaaaaatg cttgaagccg gacttcaatt cgatgccgtt tatacctctg ttttgaaacg
     1381 tgcgattctt accggacaag tcgcactaga agaaatgggt cagttatggc ttcctataat
     1441 aaaaacatgg cgtctaaatg aacggcatta tggggatctt gtgggtaaaa acaaagataa
     1501 gatgaaagaa atatacggaa aagatcaagt aaaaacatgg cgcagaggat atacggaagt
     1561 tccgccgtta accgcagaaa atagatttga ccgcagatat gatcacttgg atccgcattt
     1621 gatcccatac ggagaaagtc tggaaatgac agtgaatcgg atcattccct tatggcaaga
     1681 tcatctagca ccaaaactaa aagatcggca agatttacta gttgtgggtc atggtaatag
     1741 catccgagca ctgacaaaat atttagaaga tgttcctgaa gatcaaatgg atacgatcga
     1801 tatcccaaat gcacaaccaa tccagtatac attagcagat gatttgacaa ttctggacaa
     1861 aaaaatactt taaagaacac ctttatctaa aagtgagaga tagaaaaaag aagcaaagga
     1921 atggaacaaa aggaacatga aaaattatat atgggacttt gatggtacat tgtttgatac
     1981 gtatcccgca atggtagatg gtgcatggca agcactaaaa gattttggta tcagtatgga
     2041 caaaaaagaa atctacttca aaatgaaaaa gtattctact agttatttga tcaatgaatc
     2101 aaacttgaat gccagagagt ttaatgaatt atttcaccga tatgaaaaag aaagtacgga
     2161 agtttcccgt ccatttccag aaacgaaaca agtactggaa atgctaaaag acaacggcgg
     2221 tcgtcatttc atcctgaccc accgtttgac agaatcaaca tggggcctgt taaaagaaca
     2281 tcgattggca catctgattg aggaagtagt agggatcgat caggactttc ctcgtaaacc
     2341 tgatccagca tctttaaatt atttgatcga tacttttcat ttagaaagaa cagacacgat
     2401 gatgatcggc gatcgtcgtt tagatatcga agcagggaaa aatgcaggag tcgctacttg
     2461 tctttacgac atcgatcatt ttctgggtga gatcccggca gattatgtgg taggaaatct
     2521 gaatgaaatc cttaccttgc agagcatcat taaaaagtag tatccccttt caaaggagat
     2581 atgttataat tttcataaag gagtgataaa attatatgga aatcagaaga caaaaagaag
     2641 ttgtagaagc atttcattat gatatgagat tgccgaacca agaagtagaa acagatttga
     2701 aagtaggctt ctcgccttta aaagaaacga tcgaaaacta tccgaaagaa catagcatcg
     2761 taggagcacg cttagagttc cgtttagtgt ttgatacata tgttttatct ggaagtgtga
     2821 gtcagatcaa tcatatcctc aatcggaaaa ttgaaggtca aaatgatgtc acacaagaag
     2881 aagtggacga gctagtagca ccgttattcg atatcgtacg ccgaatgtct tatgaggtga
     2941 cagagatcgc cttagatcag cctggggtaa aattgaattt tcaatcagaa aaacaagaat
     3001 agacagtaaa aacatacctg cgatagatta aagctatcac aggtatgttt ttttattact
     3061 aattgtaagc aaaaagaatg tcatttcgat aaaaatcgtc taaaatataa aagtcactga
     3121 aaaaaatttt ttcaggagga tggttgaaga atcattctcg ggaaccttta cttccttcga
     3181 tggacttgtc attaataata tgaggaggag aaaaatgaca acactcatca cagttttagt
     3241 ggttctagtt tttgcggcat tattatatgt gttctatcgt atgcaaaagc gccatacaaa
     3301 attttcaaca cgcgtcttta cagcattagg agttggtatc gtctttggcg gtctgcttca
     3361 attgatcttt ggtgtagacg acaaagtcgt tactcaatca atggaatgga tcgggattgt
     3421 aggtcaagga tatgtatcat tcttgcaaat gctagttatg cctttagtgt ttatttcgat
     3481 cattggtgca ttcacaaaaa tgaaagtttc tgaaaagcta gggaaaatta gtgcgactgt
     3541 attgacttct ttacttggaa caacagctat tgcagcattg atcggaattg gttcaacaat
     3601 gctgttcgga ctccaaggag ctaaattcac acaaggagct gcagaaacag cacgaatctc
     3661 tgaactggca acacgtcagg aaacagttga aaacttatcg attccacagc agattttatc
     3721 ctttatccct aaaaacgttt ttgctgattt agcaggtagt cgtgcaacaa gtacgattgg
     3781 agtcgttatt ttcgcggcat ttgtcggaat cgcttatcta ggcgtgaaaa gaaaagcgcc
     3841 aaaagaagca gcattctttt cagatttagt cgacagtctg tataaaatca ttatgcggat
     3901 cgtgacgctt gttttgcgtt tgacacctta tggagtattt gctttgatga caaacgtttt
     3961 ggcaacaagt gattttgcag ctatcgtcaa tttaggtaaa tttgtcgttg cttcttacgt
     4021 agcattgctt gctgttttga ttgtccactc actgattttg attggtgcaa aagtcaatcc
     4081 aatcaactat ttcaaaaaag cctttccggt attgagcttt gcgtttactt cacgttcaag
     4141 tgctggagct ttgccattga atatcgagac tcagacaaaa gctttaggag tagatgatgc
     4201 aacagctaat ttctcagcaa gttttggttt gtctattgga caaaacggct gtgctggcgt
     4261 ttatccagct atgttggcaa cgatcgtcgc accagcagct ggagtgaatg tctttagttt
     4321 ggaatttatt ttgatgcttg tggcaattgt aacaatcagt tcttttggtg tagctggagt
     4381 cggtgggggc gcaacatttg cttcactgat cgttttaggg gcaatgaact tgccagtagc
     4441 aatcgttggg ttagttatct ctgttgaacc attaatcgat atggcacgta cagcagtaaa
     4501 cgtcagcggt agcatggtag ctggtatcgt gacaagtgca cgcatcaaag atttagatcg
     4561 cgatgtcatc aatgatgatt ctaaagtgat cgatgtgaat gcatagtcaa aaagaggttg
     4621 tgatagaagt ggtcagcttt aagaaataag aagaagtttc ctaaaaatag tttctcaaat
     4681 ttttgtgaaa tttcggctta tttccgagaa gctacttctg aaacaccgtg aataagaggt
     4741 tg
//
LOCUS       DACGLI010000108         4639 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.115, whole genome shotgun sequence.
ACCESSION   DACGLI010000108 DACGLI010000000
VERSION     DACGLI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.115"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(1..859)
                     /locus_tag="IXT22_002784"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="IXT22_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="IXT22_002785"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="IXT22_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAQ4864093.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="IXT22_002786"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="IXT22_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="IXT22_002787"
     CDS             complement(2143..2373)
                     /locus_tag="IXT22_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAQ4864094.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="IXT22_002788"
     CDS             complement(2603..3421)
                     /locus_tag="IXT22_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4864095.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="IXT22_002789"
     CDS             3582..4271
                     /locus_tag="IXT22_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4864096.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..>4639
                     /locus_tag="IXT22_002790"
     CDS             4285..>4639
                     /locus_tag="IXT22_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4864097.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDT"
BASE COUNT         1528 a          757 c          830 g         1524 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacag
//
LOCUS       DACGLI010000109         4606 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.116, whole genome shotgun sequence.
ACCESSION   DACGLI010000109 DACGLI010000000
VERSION     DACGLI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.116"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..503)
                     /locus_tag="IXT22_002791"
     CDS             complement(<1..503)
                     /locus_tag="IXT22_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4864098.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEF"
     gene            1156..1251
                     /locus_tag="IXT22_002792"
     CDS             1156..1251
                     /locus_tag="IXT22_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4864099.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            1951..2247
                     /locus_tag="IXT22_002793"
     CDS             1951..2247
                     /locus_tag="IXT22_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864100.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            2249..2671
                     /locus_tag="IXT22_002794"
     CDS             2249..2671
                     /locus_tag="IXT22_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864101.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            2690..4282
                     /locus_tag="IXT22_002795"
     CDS             2690..4282
                     /locus_tag="IXT22_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864102.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            4303..>4606
                     /locus_tag="IXT22_002796"
     CDS             4303..>4606
                     /locus_tag="IXT22_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864103.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVNGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKS"
BASE COUNT         1707 a          771 c          838 g         1290 t
ORIGIN      
        1 ctaaactctt caatacgaac tacataataa ccagtagaac ggtactgcat aagcagtcgg
       61 aatagagttt ttgcatacgt agaacgcaac gacgtgaaag cagataattc aaatctacta
      121 aattcagctg ttaaaccatt aataatatat tctaggtccg gattaacact gacttcaaca
      181 aacttttttg ttttattgat ttcaaaacca gtaaacaaaa caaagtagcg aatagaatcc
      241 tcatcttcag tacggtaagt aagattaagc atatctttat agagcttttc taaatcaccg
      301 acaaaggctt ttgtagcagt catcttataa tcacttaact cttttaattc ctcgaaagaa
      361 aatctaactt ttttcaaacc acgatctttc atacgagcgc ataatgcaaa aaataaatcc
      421 atctgcttag cattgaaatt tttcagcggt actaaattca attcattttg atatttgact
      481 gttaattccg ttttttcatc cattcctttc ttcccccctt acaaataaat aataaccttt
      541 aacaaccaac tcgtaaatag gttggttgtt attatacaaa aggatattag tactcagata
      601 aaaagttgtt agtactcaga taaaaagttg ttagtactca gataaaaagt tgttagtact
      661 cagataaaaa gttgttagta cccttctgta tccgttggga gagtaaggct caactgcccc
      721 ctaaaaaggg ttctaaaaaa tctttaaaaa ataaataaaa taaacgcgcg cgcgcgagca
      781 aaatttcccg ccaaaaaatc acccactttt taaaataaac aggttcgcgc atgatattaa
      841 actgccaatc tagctcccta tggtcgctgt aagaaggagt gatcgctacg ctctcacatt
      901 ttacttgcag cagtcgcctt taggctcctt cgccaaaaat aattcattag ggactccttt
      961 gtggcgtcct gagagctcgt ctaagccgtt ctaagacaag attcgataaa aactatgtcc
     1021 ttcgttctaa agcgccttac aggcggtcag ggcaagccct aacaacccca aggcaataaa
     1081 aaacttaggc ttatttttgc ttttttattg tataattgat tgtcgcctat ccgacagtct
     1141 tgcgactgga aggaggtgtg tttcgtgttc actaacttta tttgctccct tcttgttggg
     1201 cttttaagcg ctttgttcag ttactggttg aataaccgaa acaagaagta aaacttaatt
     1261 aaggcgactc agcccacaaa aaaagcccca gagaatccga cctctctggg gatttcgtgt
     1321 gtttcgtgtt cacttatttg caatcaaatt ataacagaaa taaatattta tttcaaaaat
     1381 atcctacaaa agtctaaaat ccgtaattat ttcttatatg caacatttac aaataaagtc
     1441 gctctgagag ctcgtatttt tcgatttaag acgttttatt tagtttttgg tgtatttcat
     1501 tggtccaagc taaaaaactc ttagaagcga ttttagagcc atttaaaccc acttaattat
     1561 attctccatg aaattcgctc catgcgtcaa aagctgcgtc tgaaattccg ccgtcttcgt
     1621 tcactagttg cattaatttt tccaacgatc gttttctttc gggtgtcata tttttatatt
     1681 ccaacaattt ttcgtctgtt aaatttggtt atcgattaca cgtgcagcac tcccccccga
     1741 attttaaaga gcataaggaa acgtgacccc acttttaaaa aaagtggttg gataggctgt
     1801 gcctatcacg tttctgaaaa aaataaatga ccccaaaata ccaatatata ggatagtaca
     1861 aggatagcaa aggatagtaa aaggatagag gtaggatagc gaaaaggata ggatcctttt
     1921 cactatccta tattatattg gaggatattt atgaatgtta aaattagaga tttagatcca
     1981 aaattcattt ctgaaattga tcgaagatgc gttgaactaa gtaatcgtac aggaaataaa
     2041 tggagtcgta atgattattt aaagctactc gttgaaaatg attttgatcg tcctttgatg
     2101 gaatacaaac aagaaaagtt tgaccagtta ttagaaaagt tttcagaaat tcaaagttat
     2161 aacacaaaga tattagaaga atatgttagc caaaataatc gtattataga aatcttgatt
     2221 gagcaaaata gaggaagtga actttgatat ggcaaaggtt atagacaaac acatttactt
     2281 tcaccaaaca catatcgatg tattggatga aactatttct actcatgcag aggttaaaaa
     2341 ctatagtgaa gctgttcgct ttttatgtat gaactatgat ccagaagtgg agaaaaaagt
     2401 aaattccaat caagcaaagt tgaatggaat gagtaaagaa atttctattt taaccgaaat
     2461 ggtttcagaa tttgcggatc ttcatttgaa agatacagga atattaattg gtaaaaattc
     2521 aactgtttat caagaagcaa aagaacgagt ggaaggaaaa attaaatcca atcaaacaaa
     2581 aaaatattcc cctcagttga agaaacctgt gaatgaatct gttcatgcca gagtagatcc
     2641 atttgatcca acgaagattc taaaaagata aaaatgaagg aggataataa tgactcaatc
     2701 gccttcagtt attctcactt gtcaatttac tttgccgaat aaaaagtcat tttctactta
     2761 tattgactat attacaaggg aacaggctct tgaagaaaag gaacgacgta cgcccgaaga
     2821 agaacaggaa cttcaacgaa tcaagaatgc tttagaggag ttttatattc ctgaaggaga
     2881 aactttttcg gagagtaaga cgggtaaaga attcagtgaa acgtcgaatg aagctcaatc
     2941 gttgatggaa catggaatca attttgacaa gttagaggaa caagatttta ccaattatct
     3001 ttcttatatg acacgtcact atgcgttaga acaaaagaaa gaactgacgc aaagtgaaca
     3061 aaaagaatac caacgcttga accaagcaat gaaaaaatat caaacagaac cccataaaaa
     3121 agcttcagga aatcttcctg gagttttttc tatagcttca gacgaagtga aaggaagtga
     3181 tctgaaggag attaagcaaa tcttccaaag aggacaacaa aaaggctcaa tcatttatca
     3241 agatgttgtt tctcatgatc attcgtatct tgaaaaaata ggattgtatg atcccaaaac
     3301 agatacttta gatgaagaag ggttaaaagc agctggaaga aaaatgatgg agacattatt
     3361 cgagaaagaa caattgaatg aaacaggtta ctggatggca acgattcacc gtaacactaa
     3421 acatatccat attcattttg cagttgttga aaaagaaaat acgcgtaaac cttacacgga
     3481 ggttgaaaat ggtgtgagtt atatcgtacc gaaaggtaag agaagacaag caacattaga
     3541 cgcaatgaag accaattatg tacatgagtt agaacgtttt tcttatgaaa aggatcgaat
     3601 gattggtatg gagaaacgaa atttattgac gcggaaaagt gatttgcgta acaccttaac
     3661 aaaagtggta aaagagccag cgcgttacga tcgacacgcg atgaacttat taaatgaagt
     3721 atataaaacc ctacctgaca aacgttcgga atggaattac ggggatgaaa aacgaaccaa
     3781 actttcacca tacacaagag agaaactcga tgagttaacc aaatatgttt taacaaaaga
     3841 acctgaatat caagaatata tacagatttc aaaagcattg aaagaagaag caaaaagtct
     3901 ttatggggaa agcaagagag aatcaaagga tgcagagaaa aatgctctct ttgatttaaa
     3961 aaagcgcaca ggaaatgcca tcctaacaga gctgaagaga caggatagtc aaataaaacc
     4021 attaatagaa agtgttgatc agatgcaatc tatttacaat gaacgatcct ttcgaacgct
     4081 taaacaattg ccaacgaatg aatacaaata tagttacgaa gaattcatga agcgcaggaa
     4141 acaattccaa caaagagttg tcacgcagcg gagtttgcgt caattaaatc gaacgattaa
     4201 tgcccatgaa gaaaaatacc acgcaagtaa agcatacgaa gagcaacaac gaagaattca
     4261 aatggaacaa gaaagacagt aaagacagta ggaggaatag caatgaaaca atatttagat
     4321 caatggaaag ttatagaagg atcattaaga gaagaacgaa tcgaacaact tcctgattgt
     4381 ttagaaaaag agcatttgtt ccagataaga gaaatgttga gaaacgaaca gtttgatcca
     4441 aatcaatttt tagtcgttga gtacccagct actggtgtgt attgttgtaa tcatgtgaat
     4501 ggtgaaaaat attttatcat tcaagaatat gagggcaagt tagcacctta ttatactact
     4561 tgggaaatga atgaagaggg aatcaataac tttccatgta aaagca
//
LOCUS       DACGLI010000110         4588 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.117, whole genome shotgun sequence.
ACCESSION   DACGLI010000110 DACGLI010000000
VERSION     DACGLI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.117"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(1..648)
                     /locus_tag="IXT22_002797"
                     /pseudo
     CDS             complement(1..648)
                     /locus_tag="IXT22_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(970..1191)
                     /locus_tag="IXT22_002798"
     CDS             complement(970..1191)
                     /locus_tag="IXT22_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864104.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(1289..1534)
                     /locus_tag="IXT22_002799"
     CDS             complement(1289..1534)
                     /locus_tag="IXT22_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864105.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1774..2388
                     /locus_tag="IXT22_002800"
                     /pseudo
     CDS             1774..2388
                     /locus_tag="IXT22_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2758..3759)
                     /locus_tag="IXT22_002801"
     CDS             complement(2758..3759)
                     /locus_tag="IXT22_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAQ4864106.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(3918..4184)
                     /locus_tag="IXT22_002802"
     CDS             complement(3918..4184)
                     /locus_tag="IXT22_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864107.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(4174..4530)
                     /locus_tag="IXT22_002803"
     CDS             complement(4174..4530)
                     /locus_tag="IXT22_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4864108.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1425 a          843 c          639 g         1681 t
ORIGIN      
        1 agtagacacc gaaaagccga agagcgttcc atttcttcgg ttctttttat atattcctcg
       61 aatggtctcc atgcccttaa tcgtggaaga ggctgtacgg agactttgat aaaatttatt
      121 tcgtcgttta ataggtcgat ggtcttgttc tattaaattg ttaagatact tcacagttcg
      181 gtgctctgtc ttagtatata aacccacact ctgtaacttt ctaaaggcgg agccaagaga
      241 aggtgcttta tcggtcacaa ttgctttcgg ctcaccaaac tgtttatgga gtcgttttaa
      301 gaaagcatag gctgcttgcg tatcccgttt ctttcgtaac cagatatcta aggttaagcc
      361 gtccgcatca attgcacgat aaagataatg ccaacgtccc ttaattttga tataggtttc
      421 gtccattttc catgaataga aggattgtct atttttcttc ttccaaagat aatagaggac
      481 tttgctgtac tcttataccc aacgataaat cgtagtatga caaacattta ttccacgatc
      541 atataacaat tcctgaactt cacgatagct tagattgtaa cgcaggtagt aaccaacagc
      601 gacaataatg acgtcttttt tgaattgttt gcctttaaaa tgattcatta ctctgtcctc
      661 tctgtctttt ttctcaattt tacactaaaa tagatttttt ggaaaacttt gcaacagaac
      721 cgtttttact atatacttct tcccagaact tgtccgtctc cttcaaatta tctctacctc
      781 tcgagttcat tgggtggttt gcccatttat taaacatgga atcacctttc tcatactcat
      841 atatttatgt cctatttcaa ttatatttat atatgcttaa ataaatttgt atcctgaaat
      901 ttattgtaat atgaagctgt attttacata tagtaaccaa agagttaata aaataaaaag
      961 agcgaaccat tatagatcag ctcttttttc attgctgttt ttaatcttat ctagaatcac
     1021 ttcaaatgtt tcaaaggtat ttacatctaa ctgacataac caaagcaagt acttcttttc
     1081 tttgtaagtc caatcaatat tacggtaaga ggacattaga ttatggtacc ttgctctttg
     1141 ttcaactgaa gccaattccc agcgtttttc aaatattttt tcttcttcca ttattgatcc
     1201 ctcgcaagac gctacctcaa acttaaataa tgggcagcga aagtctaatt ccttagatct
     1261 aagtatagca aacaaatatg aaaaaaactt agaaggtagt aaaagttctt ccgtcttttg
     1321 ctttgcttct attcttaatg tgtttcgtta tcggtgccct acaaagattt tcattaatta
     1381 cacactcatt tattgttgtg tattttctga catttctctc ttgatcaatt attttaattc
     1441 catgggcatc ctgatagttc ataggagagg agcggctatc agaaatagtt gcacctatct
     1501 cttgaacttc ttttacaact tctggaaaat ccatccatcc tgcttcagct gtcaaaagta
     1561 ataatctata atatttatct ttccttttca atctaagaaa tcgtcacccc attctttttc
     1621 ttctattata aactatttaa cttttagaat tcaaaaaccg tttgtctatt tagagtttac
     1681 cctaaataga caaaaatata acattgaaaa atttagagtt ctaacgtatg attagggtgt
     1741 attataaacg ttatagaaaa gtagggaata aatttgaaaa ttgcttatat tagagtttca
     1801 tccatcgatc aaaatgaaca acgtcaaatt gaagaaatga aaaagtttgg cgctgaaaaa
     1861 atttttatcg aaaaacaatc tggagcgacg attagtcatc ggccgatttt ccaggaagct
     1921 ttagattttg tcagagagca agatattttt attgtagaag ccattgatcg acttggacgc
     1981 aattatgacg agattatcga ttcagtgaat tatctaaaga agaagaatgt gcgacttatt
     2041 atcaccagtt taccgatcat ggctgaagca attggaaatc ctctcctaga taaattcatc
     2101 aaagacttaa tcatttaaat ctcagccatg attgctgaac aagaacgtac tgaatcgaaa
     2161 cgacgccagg cacaaggaat taaaatcgct aaagcaaacg gcgtctataa aggtcgtcct
     2221 aagttataca gtgcagacac caaagatcct caacgtcgcc ttgtctatag gagtatcgtt
     2281 caggatcttg agaatggggt tgctatctca aagattgcaa cagactacaa tgtgactagg
     2341 caaacaattt accgaataaa aaaagaaatc gaccaactaa ttgtatgatt tcttttttga
     2401 atcacgtaat tattaattag ctttgtcatc aatacagaca atcattttag attcatctag
     2461 ctaagttgat tacatttatg ttaaaaagaa tttagttaac ataaatataa ttgatgcata
     2521 aatcgtcctt atttaaaggc atttaacatt gacaacttag tataatgtat cttatgtaaa
     2581 ctaataagat ttgaatttta ttttatacac actcgataat agatcaattt tatggtcccc
     2641 cgcatttacg attgcacaag agaaacataa agtcgaccta ttagcatttc ttttcaattc
     2701 aaacattaaa aaagtttata cctctgctac taaaaaatga aattatctat ttaaaattta
     2761 aaacggtaaa tctgattcat ccaaattgga aaatggatca gcctgtattg gagctttgta
     2821 tttctccata ataacagata tctttttttc attttttaaa aaataccttt taaatttctt
     2881 atagtcctct gaaatcaaaa tatagcgtga tggatactca tcaaaagaag aatcgtattc
     2941 ttcctttaaa attcccgatt tacttaattt ttctagtaca tcaaatactc tatcactcaa
     3001 gtaactcctt aaattgttat cactttccca ttgaactact tttctataag ttgaattatc
     3061 agttgaaaag atagaatttt catccataaa cgcatatatt agcagcaatc tttcatcatt
     3121 gtcaaattct attggatcaa aaatatctaa gttgtcatca aaatctttat cagttccggt
     3181 aacttttttg ttaattactg aaggtgtctt gtaagaaata gaatctaaat caaagcgttt
     3241 tgattctaaa ttattttgtg ctttctcaat taaataattc actttttttg tgagaaacct
     3301 tctgatattg tctttgctat atgttccata aaaaccctta tcttctaaag agtccctgta
     3361 cttcttaact tctatatact cttcagccaa aacttgtgga actggttcat ctaagaaaaa
     3421 aacccctacc tcgcctttgc tatttttata aaagtaatca atttctgcta tagttcccga
     3481 tctataatta tcaactggag aacccaactt atggccaaaa atcgctaata atatatcact
     3541 attttctaca atttgtttat taataacact ttgcccagag ctattattta tataagtagg
     3601 aatcgcattc gtttcccatc gaattggcat caaaattact tttgtattat ctgtattttc
     3661 tatattccat ctatatatgg tttcttctac ttcattcctc tttgctgcta tatcacctgg
     3721 tgatgctata aatactttta ttagatttat ggttttcatt tattgtacct ttctctttat
     3781 gtctctttaa agtaattttt gtataaaatt tattgacttt tacactatag gacaactttt
     3841 atctatttag tacaaaaagg cccactaaac taattgatta gttaggagcc tattacaggt
     3901 atattttcaa ctcgctttta agcaaattct actaccagct ttttgcctaa tgccctagcg
     3961 atatcatcaa gtttatcgaa agatacgtta tcccctctct caattcgagc aatagtagat
     4021 tgagttgtat gtgctttttg tgcaagctcc gcttgagtta ggcctgcttc ctcccgtgca
     4081 tgataaagag caaccgcagt ttcgagtttt cttccttcac ggtcatatgc ttctgcaaaa
     4141 tctttgtctt tttgcttttc ttcaatcaat tttttaatca tcatttgtga accactcctc
     4201 tctaagttct tttgcatgtt taagttcact tattggtgtt ttctccgttt ttttagtaaa
     4261 tccatgggta atgacatacc ttccattgac cacatggaaa tagatagctc tttggatgtt
     4321 tgatcctacc ttacttctta attcgtacaa attagtgtct aattttttca cccatttcaa
     4381 ccgttgagct actagcatcc cattcttttc tgtttcttct attgtacgta aaagcttcgc
     4441 actatctttt tttggtaatg tttccaacca ttctaaaaat tcatcatgac cattaggtct
     4501 tttaaatgtt tcaaaagata ttttttccat acccaattat atcatatatt gattttatat
     4561 tatagtatat aacataaaaa ttcgaatt
//
LOCUS       DACGLI010000111         4526 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.118, whole genome shotgun sequence.
ACCESSION   DACGLI010000111 DACGLI010000000
VERSION     DACGLI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.118"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..219)
                     /locus_tag="IXT22_002804"
     CDS             complement(<1..219)
                     /locus_tag="IXT22_002804"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4864109.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRPQRSNKPI"
     gene            complement(330..584)
                     /locus_tag="IXT22_002805"
     CDS             complement(330..584)
                     /locus_tag="IXT22_002805"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4864110.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(777..1052)
                     /locus_tag="IXT22_002806"
     CDS             complement(777..1052)
                     /locus_tag="IXT22_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAQ4864111.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(1024..1977)
                     /locus_tag="IXT22_002807"
     CDS             complement(1024..1977)
                     /locus_tag="IXT22_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4864112.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2589..4082
                     /locus_tag="IXT22_002808"
     CDS             2589..4082
                     /locus_tag="IXT22_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAQ4864113.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4217..4513
                     /locus_tag="IXT22_002809"
     CDS             4217..4513
                     /locus_tag="IXT22_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4864114.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1478 a          752 c          793 g         1503 t
ORIGIN      
        1 gatcggttta ttagaccttt gaggtctata ttttttaact acaatcgacc ttaaatttaa
       61 ttgtttcatt agcttttgga catgtttaag agatactgaa atcccttctt ttaataaaac
      121 ttgatggatc tttgtggcac catagcgttg tttattcgta aaaaaaattg ttgaaatctt
      181 ctttttcaac ttattatttc tgatttctgt agctgtcaac ggtttattct tataaaaata
      241 atagacactt ctagggattt ctaataaccg acacaacaaa gaaacagtgt aatccttaca
      301 ccatttttca ataaattgaa caagcgaatt taggttttcc gagagaatat ggctgcggct
      361 ttttttaaga tttcaagttc ctcatttaaa cgagcatttt cttttctcag ttcagctact
      421 tcttttccag tcagtcctgt ggactgatca ggtaaatata aattcttcca tttgtaaatc
      481 gttgcttcag ataagccata ttctttcgct aaccctcgaa cagaacgtcc agtttgattc
      541 agttcaacaa tcatttgttt aaaattttct tcatatcggg tcataaaaat tcatcctctc
      601 gtagataagt ttaatttatt cttgtctcta cgaaaagctg tctaagattt gatactaaca
      661 ccaaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
      721 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
      781 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
      841 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
      901 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
      961 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     1021 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     1081 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     1141 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     1201 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     1261 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     1321 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     1381 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     1441 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     1501 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     1561 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     1621 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     1681 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     1741 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     1801 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     1861 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     1921 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     1981 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa tatattcgat
     2041 atatctaata tactccaaat tgataagaat tcagacttta taaggaatat agtggatata
     2101 ctaaatatat ttgctatatt cagtatatca gatatattca aaatgtcaaa atatatttgt
     2161 gcgttttgcg ttgacaattt agagtgaaaa gaggtaaact taattctata gaaaccacag
     2221 ataattcact atttacaaag tagcaaaagc agtggtactc tttaaacaga aaaattacat
     2281 aaaaaaaaga gacggaaata attgatttta gcagaatcaa ttatttctga atcacatggt
     2341 taggacatgt gttcacgctc gtctcaagaa tatgtaagta gctaccaact acttatatta
     2401 aaagttgatc ggataccttt tccgattgcc tttattctac caaaaaaagg cgagcaactc
     2461 aacagaagaa cgtttattta gtgtacttaa attaaatatt cttaaacact gaagagagaa
     2521 cacatactat ggctgagatt aaagctaaac tgtgttctct ttttgtttga gaaaggacgt
     2581 tacaatcgat gttgagcgaa atttattcag ctattcttaa aaacggctta cgtacataca
     2641 aatatcgaaa cagcaccatg aaacctgcag gtcatattga ttccagtagg agtggtgcta
     2701 tctttgcgta ccgtagcaag caattaatga atgttgggcg tggtatggtc attacttcgg
     2761 aagaagctat tttagagaac gaaaagaaac taacgcattg gacacctaat acctatcgct
     2821 ttggtactta tgcggatgat tatcgaacag tggttaaagg tcattctgag aaaaacttaa
     2881 gtcaaatcaa cacatttgta gttgatatcg attcaaaaga gaaccatcaa ggcgaaatta
     2941 ttttagcctg tttagatcaa gtgggctaca tgccaacgct aattttagaa tcagatcatg
     3001 gttatcaagt ttattttgta ctaaagacac caggctatgt cacaaagaaa agcaatttca
     3061 aggtgatcga tgtagcaaaa aaaatttcaa aaacaattcg tctacagttg gctgaaaaat
     3121 tgtccggagt ggatctagga tgtaaccact tcggaattgc tcgattccca caagaaaata
     3181 atattgtttt taaagaaatg aactatcagt attcttttgc tgactggatt caatggtcga
     3241 tgaagcttga atcagatcaa aaaacaaaag aagatcgaga acgaaaacta attgtctttc
     3301 ctgagaaaaa agaaattcgt caagtagatg aaccgtggtt cgatatgtta cttcataaag
     3361 caaacatcgt cggcggagaa ggacgtcttg gtcgaaataa tgtgattttc acgctttctt
     3421 tagcttatta ctcttcaggt tatgcattgg atacttgcga atacaatatg ttcacattca
     3481 acgaacggtt acaggaaccg ctatctgaag cagaattagt aaagattgta cgtagtgctt
     3541 attctggtaa ttatcaagca gcaagcagag aattcattat tgaattgtgc cagcaatggg
     3601 tttcaccaac cttaaaaaat aatgatctgt tcattcaacg acgtggctgg tggaaattta
     3661 aaaagccacg agatcaaaga aaatatagtc ataaaaatga atggaaagaa gatctattgg
     3721 cttatctaag cgaaaaaagt cttgctagtg agccttattt gaacctgtca aaaaaagaat
     3781 tggcttcaca actaacgatg cccaagcgaa cacttgataa gatcttaaat gagttacgag
     3841 aggagaataa agtcttctac aaggtaacac gaggaagaaa tggcggaatg atcattgctt
     3901 cagtcaaaac gttgttcgcg agggttattc aactaagtaa agaaaagaga ctagattatt
     3961 caacaaggat cacagaggta tttggactca acgagagctt agtagaagag acatttagac
     4021 aattatcaac ccccttgaac cctcttaaag aagtgaatct ttttgaagta gatacaggtt
     4081 gaaaaataaa aggtgcaaat tgccttatac aatatatcta tgatacttct gtaggtgttg
     4141 ctccctttgc ctagctacgt gtaggtggta tacttataac tgcgtatgca gtcttatgta
     4201 tcatggagga agttgtatgt cgttaaaaaa ttatgtctat tcacatcctg ttaatgtgtt
     4261 tatcattggt cgtttgggat tatctgtgga agtgttctgt gagctttatg gttttaagca
     4321 ggggactttg tcttcttggg ttaccaggga aaaaacagtt gcttctttgc cgattgagtt
     4381 tcttcatggg ttgtccttag cttctgggga gactatggat caggtatatg attgtttgtg
     4441 tgtgttagag caggagtata ttgagtataa aatagctaac gagttaagaa aaaggaagaa
     4501 gtatatccag tagtagtttt tattta
//
LOCUS       DACGLI010000112         4425 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.119, whole genome shotgun sequence.
ACCESSION   DACGLI010000112 DACGLI010000000
VERSION     DACGLI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.119"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            690..1658
                     /locus_tag="IXT22_002810"
     CDS             690..1658
                     /locus_tag="IXT22_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4864115.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IXT22_002811"
     CDS             1669..2484
                     /locus_tag="IXT22_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAQ4864116.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IXT22_002812"
     CDS             2552..3262
                     /locus_tag="IXT22_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4864117.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="IXT22_002813"
     CDS             3298..>4425
                     /locus_tag="IXT22_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4864118.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DACGLI010000113         4415 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.120, whole genome shotgun sequence.
ACCESSION   DACGLI010000113 DACGLI010000000
VERSION     DACGLI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.120"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            58..912
                     /locus_tag="IXT22_002814"
     CDS             58..912
                     /locus_tag="IXT22_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4864119.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="IXT22_002815"
     CDS             1009..3258
                     /locus_tag="IXT22_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4864120.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..>4415
                     /locus_tag="IXT22_002816"
     CDS             3261..>4415
                     /locus_tag="IXT22_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4864121.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          805 g         1429 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctaga
//
LOCUS       DACGLI010000114         4371 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.121, whole genome shotgun sequence.
ACCESSION   DACGLI010000114 DACGLI010000000
VERSION     DACGLI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.121"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            106..357
                     /locus_tag="IXT22_002817"
                     /pseudo
     CDS             106..357
                     /locus_tag="IXT22_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            450..1244
                     /locus_tag="IXT22_002818"
                     /note="aph(3')-IIIa"
     CDS             450..1244
                     /locus_tag="IXT22_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4864122.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1654..1765
                     /locus_tag="IXT22_002819"
                     /pseudo
     CDS             1654..1765
                     /locus_tag="IXT22_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1786..1869
                     /locus_tag="IXT22_002820"
     CDS             1786..1869
                     /locus_tag="IXT22_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HAQ4864123.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1994..2731
                     /gene="erm(B)"
                     /locus_tag="IXT22_002821"
     CDS             1994..2731
                     /gene="erm(B)"
                     /locus_tag="IXT22_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4864124.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2994..3857)
                     /locus_tag="IXT22_002822"
     CDS             complement(2994..3857)
                     /locus_tag="IXT22_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAQ4864125.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3859..4131)
                     /locus_tag="IXT22_002823"
     CDS             complement(3859..4131)
                     /locus_tag="IXT22_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4864126.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4148..4363)
                     /locus_tag="IXT22_002824"
     CDS             complement(4148..4363)
                     /locus_tag="IXT22_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAQ4864127.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT         1352 a          735 c          822 g         1462 t
ORIGIN      
        1 ttcttgggag ttttgagact actatatgcg tttttttgtt gatttaccaa catgtttaga
       61 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
      121 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      181 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      241 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      301 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      361 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      421 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      481 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      541 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      601 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      661 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      721 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      781 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      841 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      901 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      961 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     1021 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1081 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1141 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1201 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1261 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1321 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1381 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg ttattttgta
     1441 catttaactt gacggtgaca tctctctatt gtgagttatt agtggtacag ttttcaaccg
     1501 ttttaattat aaaaaagtgg tgcattttta aattggcaca aacaggtaac ggttattgca
     1561 ggtgtatttc ttatctatgg gtttaacatg gattttatca ttaaaatcat gagtattgtc
     1621 cgagagtgat tggtcttgcg tatggttaac cctaaagtta tggaaataag acttagaagc
     1681 aaacttaaga gtgtgttgat agtgcattat cttaaaattt tgtataatag gaattgaagt
     1741 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     1801 atgcgttatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacgca
     1861 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     1921 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt gtttatagat gtaatcactt
     1981 caggagtgat aacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     2041 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     2101 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     2161 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaatactcg
     2221 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     2281 aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     2341 aagccgtgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     2401 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     2461 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     2521 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     2581 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     2641 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     2701 tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt aaatttggaa
     2761 agttacacgt tactaaaggg aatgtagata aattattagg tatagggcac ctctaataac
     2821 taccaattaa ttcacctcaa aatgaaatta gaaaaaaaca gcgaaatttt taaatctatt
     2881 tcttatcgat acaaattcct cgtaggcgct cgggacccca acatgaggaa atgtttttat
     2941 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaata
     3001 cctggaagtt taggtgtttt gggtattggt ggtgtaggtg gctgcaagct ttccaatttt
     3061 tgttgaattg ctttaaattc aggtgtctct tggtgtttat ttagaaccat tttttgctct
     3121 attcgttcta aagtcggttg aatttctttc cctgatactt tacgattcaa ttctttttct
     3181 aaggtttctt ttggactaat agaaggtgtt tccaaacttg aatagagttt tactccttct
     3241 ctgttatata gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
     3301 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctggc tgtcattgga
     3361 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
     3421 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
     3481 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
     3541 aaacggctta tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg
     3601 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
     3661 ttatcaatga caataacatt cccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt
     3721 ttccctgacc ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt
     3781 ccttgaatca attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa
     3841 ttgactatat ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg
     3901 attcattgac cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag
     3961 atttacacgt tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc
     4021 atttttattt aattcatggt tcaaaacata gtttaatact cgattataaa cgcttgccga
     4081 taattcgtta atgatctcta tttcaaatgt tttttcatac gtaactgcca tttcattttc
     4141 actcctttta aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca
     4201 taacttcttt tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt
     4261 cagcacgaac acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat
     4321 catttcgttt tgctttttgt gcgcctaaat ttcccacaat cactcacttc t
//
LOCUS       DACGLI010000115         4281 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.122, whole genome shotgun sequence.
ACCESSION   DACGLI010000115 DACGLI010000000
VERSION     DACGLI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.122"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(37..1257)
                     /locus_tag="IXT22_002825"
     CDS             complement(37..1257)
                     /locus_tag="IXT22_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4864128.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1277..1882)
                     /locus_tag="IXT22_002826"
     CDS             complement(1277..1882)
                     /locus_tag="IXT22_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4864129.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1931..2863)
                     /locus_tag="IXT22_002827"
     CDS             complement(1931..2863)
                     /locus_tag="IXT22_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4864130.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3283..4143)
                     /locus_tag="IXT22_002828"
     CDS             complement(3283..4143)
                     /locus_tag="IXT22_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864131.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1218 a          861 c          701 g         1501 t
ORIGIN      
        1 tttattcttt atttaaaact ttgcaacaga acctttttat tttacagaag cactcgaaac
       61 tgcatctact gcagtttcat cgtgtgtgct ggcgctggtt actgcatctg tttttccacc
      121 atgaacagat gcacttgaaa ccgcatcttc atttccaaca agttgttgac ccgtttgttg
      181 taaataccac tcaatgattg gtttgaaatc aagaatgtat tcattgattc cagcatactc
      241 tccattttca tcatgcattg cttggtaatt atgcacaata tatttttctg gcacttgttt
      301 tggtacatga acacgtaccg catctgttgc tccgcttcgc agttgttgaa ttacccactc
      361 tacattttta tacgattttt ctgggtgaca gttggctaat ggattcccta cctgaccggg
      421 cacacgagca gctaacatct ctttcgcttc ttggcgcaaa ttataatata aaaattggtt
      481 attattatct gcaaaagtta attccatcgg catcgaatct aaaaagtaat tgatttgatc
      541 cactgtcaat aacccacgat ttaatttgac gtaagtattt ccagaaacgg caccgactgc
      601 ttcagaagct ttttccaacc aatgatcatc tgacatatca acatcgggta ttgtcgtagc
      661 aattgttcct gtcgcatgca aatcttctgg tggaagcttt ttaggccctg ctaaggtaga
      721 cacgacttta atgaatttta caaaacttgc taatgtactg cctaaaaagt caacagttcg
      781 tggatcaatc aagcgatctt cttggtcaaa tgcttctttt gcttttccca ataaaaattc
      841 atttccgggc atcactaatg cattcacgcc tggtgcgtcc aaaatttggc gcaagtgtaa
      901 ttgcgcgcgt gaagttcctt gatcgtagta agaagcaccc acaaccatta caggtttatt
      961 ttcaagtgga tggattttaa atgatagcca ttcaagtgca cttttcaatc ctgctggaac
     1021 cgtatgattg tgttctggcg tagcaataat taccccatca gccattaaga ttttgcgatt
     1081 tagctgttga atagcaggac tatttgtttg atcatcatct tgattgaaca gaggtaaatc
     1141 tttgatttca atgatttcta aattaaatag ttcatgatat tgtttttgga taaatgttaa
     1201 taatttacgg ttatatgaaa gttcagctgc tgatccgacg atacctatta atttcatctt
     1261 tgtttgctcc cctcgattaa atcgtttccc atgaaaagct ttcggcttca cgtttatttg
     1321 cttggtgcgc atgttgcaat tgactagtga ttgtgacaaa gagtaagaaa tctttgaata
     1381 gttcacgtaa ttttgcgact tgttcttcat caatgagtcg tccttgctca tcaaaggctt
     1441 ggagtgaatg acccaataaa aattctgagc ttggcataat tcgtgccttt aactctggtg
     1501 aatccaatat ttggcgcaaa tgtgcttgtg cgcgtgaaga acctaacgtg ccataagacg
     1561 ctccggtaat catcactggt ttatccacaa acggaaaaat accatatgaa agccaattta
     1621 atgcgttaat caatgaagca ggaaccgcat ggtcatactc tggtgtgctg atgattacgc
     1681 catctgcttg ttcaattttt ccagcaattt ctttaacaac atttggtagt tctgtgtttt
     1741 caggtttgtt aaatagtggc agctccttga tttcgacaat ttcgatttct gcctcattta
     1801 caaaataatt tttcataaac tgtaataatt cacggtttgt tgaccgcgtt gaatttgttc
     1861 ctactaatcc aataaatttc atcttcattc tctttccttt ctaacatcga tttctgactg
     1921 ttcgcacgta ctaaattttt tcaaatcctt ttgtatacaa gaattgattc tcttttgtta
     1981 caactgctcc ctcgataccc ggctgttctt caagcgcttt caacacttct aaagaagatg
     2041 ctccaaataa acgtgtagtc cagatttctc catctacaga agaatcagac aaaatcgtca
     2101 ggcttgctac gtcattttta actggaaagc cagttttcgg atcaatgatg tgatgataca
     2161 ctgacgaacc attttgtaga taacgttcgt agattccaga ggtaactaaa gattggttgt
     2221 ttagtttaac caccgcaagc gactcttcac gtgaaccttt aggatttcgc aaaccaatac
     2281 gccaagcacc atccgaacgt cttggtgatt caccaaaaac aacgatattt cctcctaagt
     2341 taactaaagc aaacgctgca tttcgctctc ggcaatgtgt aattaattta tctgcaatgt
     2401 aaccttttgc taacgccccc aagtcaatca tcattcctgg tttggttaaa aaaacggttt
     2461 tcattttttc atctaattga atttggtgtg gatccgttag cagaagtaac tcagttatct
     2521 ctgcttttgt tggaaccaat gcatcttcaa atccaatgtg ccatttttgt acaaccggac
     2581 caatagcaat attcagataa ctatttcttg cacaactatg tgcttttcct aatttgatga
     2641 gctcaaaaag ttcaggatgt acaatcacag cttgtcgtcc agcagcttga ttgatggcca
     2701 ttaattcaga agttgcatca tgtgcgctga agcgatgttc ataaacgtgc aaccattcgc
     2761 ctaactctgc tagtaatcga ctaggctctt catgcccaac ttgtaatgta attgttgtcc
     2821 ccatcatttg ccagattttc gtttcttcga tcacctgatt cattttgtac cttctttact
     2881 tgaactacgg attacatgag taattagttt ttatttttgt tactgttttc acaaccagat
     2941 gatacgcctg ctagatttat ttgtcaaccg attttatata tttttttata taataaggta
     3001 attttaatat aaaattttat attgtaaaaa acaaataagg gaaacaaaca acacattttt
     3061 gtgtgttgct tatttccctc taactatcgt tttctatttg atggttaacc tacttaaaat
     3121 aaatactgca acgacaaacg gagatcaagc atgctttgta acgtatttta cgataattac
     3181 gactttattt tattactcta tcttgctgcc atacccgtct atccctaatc atctttggtg
     3241 aattttttca aagttagcat aacaaaaata agtatttttt ccttagttaa tcaatagtat
     3301 catttttttc atatgattta attcatcaat taattttttg tttttattaa ttttagcaaa
     3361 agctagtgca tcttgaatca attcgagcac ttctgccttc gacttatttt tagcctgtgc
     3421 gttcttcgct aattgggcag cagctcgtgc taagtaataa gtcaaatggt tatccgaaca
     3481 aatatcgatt gcgtaattta gtagtgcatc acttgtttcc aaatcaccgt cttgcgcaaa
     3541 aaaaacacca caatgaaaga cgatatttaa cacccgccag atatcttctg ttgtacgaat
     3601 cggatacgta taaatttttt caaacactcg attgaaataa acttctgctt tttccaactc
     3661 tttttctcta gcatagacca ttccaatacc tgtatatgcc aataaacgaa acaacgtgtt
     3721 ggctgtttct gccatcaaca actgatcaaa atggaacaac acatccgtaa ttggtgcatt
     3781 cgtaaaaatc atttcaaatc cttttagata gtagtaacgt gcaatcagct cagactcgtc
     3841 aattaccttg ggatcaatgg ctgctaaaat ctgtgtcaat tgttcatatt cactcgtaat
     3901 cagtgaaaac tctgcttttt ctagctgttc atcaagttgt gtattgatca cgttcatcga
     3961 agaaaaaagt tcaactaacg gaagattgat tcgattacat aatttgatta aaatttttaa
     4021 cgaagggact tgaccattgt tctcaaattt acttaatgtt gcttgtgtac aaattccttc
     4081 agacacttct ttttgagata agttggcagc ctttcttgcc gtaataaatt tttcaatgtt
     4141 cattattttc tctccaatca gacctcacac gaaaatcatt tctgtctcga ttttagcatg
     4201 ttttctttgg gaatgcttta ggttctgttg caaagtttta aataaagaat aaagtccctt
     4261 acggtatcta tgatttaagc t
//
LOCUS       DACGLI010000116         4170 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.123, whole genome shotgun sequence.
ACCESSION   DACGLI010000116 DACGLI010000000
VERSION     DACGLI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.123"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..749
                     /locus_tag="IXT22_002829"
     CDS             <1..749
                     /locus_tag="IXT22_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAQ4864132.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKL
                     ALMGITISIPPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSVKGLES
                     RFESILLAYSVLLSRAQRRFEGTLRYSLGY"
     gene            complement(808..2610)
                     /locus_tag="IXT22_002830"
     CDS             complement(808..2610)
                     /locus_tag="IXT22_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAQ4864133.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(2673..3515)
                     /locus_tag="IXT22_002831"
     CDS             complement(2673..3515)
                     /locus_tag="IXT22_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864134.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            complement(3531..3752)
                     /locus_tag="IXT22_002832"
     CDS             complement(3531..3752)
                     /locus_tag="IXT22_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864135.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            complement(3895..>4170)
                     /locus_tag="IXT22_002833"
     CDS             complement(3895..>4170)
                     /locus_tag="IXT22_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HAQ4864136.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
BASE COUNT         1258 a          842 c          608 g         1462 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaatc catgaaaagc
      481 ttgcccttat gggcattact atatccattc cgccacgtaa aaacatggat aaatcagaaa
      541 aactagacca cagcttactt ggaaaacaaa gaaaaacagt tgggactgtt ttttcttcct
      601 tagaaaaatt aggttgtcaa aatttcaact cacgttctgt taaagggcta gagagtagat
      661 ttgaaagcat attactggct tacagtgttc tattaagtcg agcacaacga cgttttgaag
      721 gaactttgag atattcttta ggatattaaa attaactagc accacgggta tctattaaga
      781 agatcctagg ttatcttaga ttatctgcta atctttgtat ttccagtagt atcctccagc
      841 atgtttttga actccatttg cagcatccct aatacttttt gagttaacgc caacttcttt
      901 tacagcagaa gctatagtat cgaattcttt tattattgtt ccatcatcag tcatttgaat
      961 aatctgtctt ccacgcttct tgctaggctc actaatcgca tcctcttttt tgttcgcttt
     1021 tagaaaatca gatttttcct tagctatccg ctctgcctct tgtttagcaa ataatagctt
     1081 aattgcctta tccctacgag cctctaaagt accaacatcg tgccgtgttt tacgcataat
     1141 tccttcatca agaatgagaa tttcattatc gtaatcctta atttttcgat aagctttagc
     1201 ataagaatca tatagcgcag gagcatcata gccgttatat cgagctttat caaaaagtgc
     1261 aatagcttca tctactttgc catttttcct agcagtttct ccacgttccc aatatggata
     1321 acctgcatca aatcctttct cccaattccc tatatttcgt atcttgttta atgaaactcg
     1381 attatgcaac ccgttaataa ttacatcttc tctagatatc actttttcaa tatttaggtt
     1441 aacttcagtc tcatcatatc cacgattttt tgcatcgaat aataactctt tcatcgctga
     1501 ttttgaaata gatttcagca tactaaggct ttgctctgct tcttttttag tgtaattact
     1561 aacactcata tattcattca tagaattata acaatcgcta taagcactga aaatataatt
     1621 tgaaagaggc gttaagtcaa aggggctacg aaaatagact cgcacatttg ttgtaccgcc
     1681 ttcacttaca gtacaaggtt ctataggtaa atcaattcca tttgtagcat cttttctaat
     1741 aatgatgtaa tttcccttct tagcaaactt aaactttaag aatgtatata gacaagttac
     1801 atcgacataa ttattactgt tttttcgata cctgatccaa ctggtgtcgc atcctttttt
     1861 ctcaataata tcttgaataa aagcacaagc ttcaagttct tttatgtctg gagtcatctt
     1921 ttctatttgc tttttttgtt cttccaacga ctcctcaata atatctaaaa caccccaaaa
     1981 aatctttccg catatatctg catctgattc cgctctatgg gcagtgtcat ttattaatcc
     2041 gaaatattcc gctacagtct cttgcttatg atttacaatg ccttttatat gttttctaga
     2101 gagactcaga gtatcaacat acttaatttt agcatcatac ccaagtctag aaaatgtgtt
     2161 acttaaaaat ccaaaatcga aacttgcatt gtgtgcacac atagtgattt ttccatctag
     2221 tgcatctcct aaaaattcta ccaactgggg gtaaacttcc tgctcatttg gagcagagtt
     2281 tagcatttca ttagttatat tatttattgc cgaagctgag gctgcaattc taacttttgg
     2341 attgacaaga gttccgaatg attgaattgg aactccttct ttaaatagca ccgcaccaat
     2401 ctctacaatt ctatctgaag aagaatttag gccagttgtt tccacatcaa aagcgataaa
     2461 agttttacga aactcatcta catttgatat gtccacttcc aatttttcag caaaaacttt
     2521 accagtacga aatagactag aagccagttg ataatcaacg tgtttactaa cctttccttg
     2581 ttttttcttt agaaaatcaa ataatcccac tattatttcc tcccccatta attttatcca
     2641 gaatcacttt tacgatgcct ttttcttata ttctacctat tcgcatacca caagaagtga
     2701 tctaactttc ttcttctaaa aggaatatgt atattatttt catcaagtag ttttccaaca
     2761 cattcgttaa atgcctcgta atcaaaactt cttcgccacg tatcaatctt attcgtagtt
     2821 agtccttgga tatagtgtgg aagagtattt ttaacgatac catcaaagat ggagtaatca
     2881 tctctcccac acacttccac attatgatat gtacagtact tggatgcaaa tgagaacata
     2941 ttaactgcac caatgttcct tgcgataata tttatcaact gaggatctcc ttttgccaac
     3001 cgatcatcaa aatttggaat ctccagaatt actttagcca aatcatatag agacaacctg
     3061 ctcttatatt gagaaagatg tgttgaattt gttacatcaa ttaccgcaat cttcatcgca
     3121 atagtattta aatcattatg aagaggaaat gcattcaaaa catcatgtat tattagacct
     3181 tctttcccat aattagagct tgcacctaca aacttatgct gtttctcaat attttcttca
     3241 gttaaagata agtatttttg tttatggatt gtttcactta tagttttttc tttacttgaa
     3301 tcaagcttaa gaaccttgtc aatgcaccaa tatgttgttg ctccttttat tggggaaata
     3361 tcattctgct taagatattc ttttaataaa ctcagttgtt ttccttctgg aatagtacca
     3421 gatttcgttt ctatgatatg aggttgtggt ttggaagtac cttcattagc agcaaataca
     3481 gcatactcaa catcatttat tgttatgatt ttcaatacaa attacacctc ctaattacct
     3541 atctttattt cattgccatc aggcaatata aaagcctgca caaacttgac acctagcaca
     3601 tcagcaatcg ctttcaactc atctaaggtt accgtttctc gttgtaattt cttattgaaa
     3661 ttctgtggag tctgtccaat acgtctagca agttcggaaa cacttatatt catttgctca
     3721 cacagttctt taatcatttc tgccgtagtc atacagcacc tccaagttta cgctaagaat
     3781 attataaatc atttggttta taataacaat agttattaaa atattattat aatcagcaag
     3841 caaaagaaaa cccacgactc tactgtagaa tcatgggcta tttacttctg gttttcatat
     3901 ttccatttcg atgccagatt tgaaggatat gacgaagtgt tcttcataga ctgtaacgct
     3961 ctggattatc ttccttacaa gcttatcatc gtactctaag gtacggaatt tgttcttgcg
     4021 gataaattca atcagctcat tgattcgctc gttctcgcca ctgagggagg catcttctac
     4081 taaaaggagc tgtcgcttgt ctctcagctc atcaatctca tctgctagat gttcataatc
     4141 ttgaccctta ttagccagct tgatgagttc
//
LOCUS       DACGLI010000117         4149 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.124, whole genome shotgun sequence.
ACCESSION   DACGLI010000117 DACGLI010000000
VERSION     DACGLI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.124"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..275
                     /locus_tag="IXT22_002834"
     CDS             <1..275
                     /locus_tag="IXT22_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4864137.1"
                     /translation="LDSFASPHYFPPNTKVTERIMVKGLLYDHSEWGNLAKNTKKKYR
                     DLLKQESQNDELTNHLRESFAESADDLKRELDTWLQGLDVTEVGAE"
     gene            272..691
                     /locus_tag="IXT22_002835"
     CDS             272..691
                     /locus_tag="IXT22_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864138.1"
                     /translation="MSNPVEKMTIKNLADELGVSKNTVRNQLVNSGFDLAQYKENGII
                     MLDKELIGVVRSIYRSKSDQLTGQLPVNNTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            700..1008
                     /locus_tag="IXT22_002836"
     CDS             700..1008
                     /locus_tag="IXT22_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864139.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            1012..1374
                     /locus_tag="IXT22_002837"
     CDS             1012..1374
                     /locus_tag="IXT22_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864140.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPDESDGLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            1595..3001
                     /locus_tag="IXT22_002838"
     CDS             1595..3001
                     /locus_tag="IXT22_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAQ4864141.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQTNIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPNLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDVHEYKEIMSEISELRQTAVKERESVSDELRYISRQREE
                     NEREKALVASERVKIEEEKKNMLNVKKEMAVIFQKDIVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQRKLERSEDEIEW"
     gene            3448..>4149
                     /locus_tag="IXT22_002839"
     CDS             3448..>4149
                     /locus_tag="IXT22_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4864142.1"
                     /translation="MSKRGTIVNEWEKLNRISNRRLKYQSLTLPLKMQWSIDRITIVG
                     KLKENIYYHTPNDVLILNFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     HEGKGRIDFNPNKINQFLSGSMKNFIHDLFLEPHFSRADIACDIVDIPDDFVSQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKIVPPEITTWWRLELQ
                     LRRGKATDWHEMVHES"
BASE COUNT         1444 a          602 c          930 g         1173 t
ORIGIN      
        1 gtttggatag ctttgctagt ccacattatt ttccgccaaa tactaaagtt actgaacgga
       61 ttatggtgaa aggtttgctt tatgatcatt ctgagtgggg aaatctagct aagaatacaa
      121 agaaaaaata cagggatttg ttgaagcaag aaagtcaaaa tgatgaattg acgaatcatt
      181 tgcgagagtc atttgcggaa tcggcagacg atttgaaacg agaattagat acatggctcc
      241 aaggacttga tgtaacggaa gtaggtgctg aatgagtaat ccagtagaaa aaatgaccat
      301 aaaaaatctt gctgacgaat tgggtgtatc gaaaaataca gtgcgcaatc aactggtcaa
      361 ttcagggttt gaccttgctc agtataaaga aaatggcatt atcatgctag ataaagagtt
      421 gattggtgtt gttcggtcaa tttatcggtc aaaaagtgat caattgactg gtcaattacc
      481 ggtcaataac acaggcagtg attttccttt agaaaaagag aatgagtttt tgcgtgatca
      541 attagctgag aaggacaaac atatttctga attaacagaa atgattcgtg atcaacaaaa
      601 attgaccctg cttcagcaac aaaaaaacga tcagttgtta ctagaaaatc aagaattaaa
      661 aaatcgaaaa tggtggcaat tctggaagtg aggtgtgaca tggataaaat tgatttgaga
      721 gaagaaacag tcgatagaat tgaattgatg tatgaacggt tagctgatta tttgaatttg
      781 ccggatgaag ataattatag tgaaatgctt gaacgaatta tggatgttct caactcggtt
      841 atcaatgctg atttagcaaa atcttcagtt ttgactaatg aatttgttca taagcattta
      901 gcgcaaacaa ctgatgaatc agaaaaagaa ttttggttga aattaatgag tcatgttatg
      961 cagttaaacc aaatttccgt tattaattcc aaagaaaagg agatgtagtt tatgggaatg
     1021 actttagcag atattaaagc gcaagaagaa aaattaaaaa aagaacaagc gaaacttcgc
     1081 caacagaaaa aacgcttgat tgagaaagaa aatgctgcaa tgggcaaggc tcttcgcaag
     1141 cgttttgggt ttgaaacttt tgctgatttt gagcggtggc tatcgtcgat ttctgacgat
     1201 cagcaacacg aaaaatcagt ggataatgag tggcttgctg atgaaaaatc agcgccaagc
     1261 gaacgagatt atcccgatga atctgacggc ttattcggag tgataccgaa taagaaaagt
     1321 cagatgagtg agagtaaatt tacgtcaata tttaatgacg tgaatttacg ataagcgatt
     1381 attttgcgtg aagcaaaata aagcgtaaaa ggagttgaga gcgtgacacg ctttcggctc
     1441 cttttttcgt tgtcacttgt gacagcgaat accctcggag agcatttgga attgtgacag
     1501 ccatgtcaca attaggaaaa tgttactctt tgacaaagag taacagaaag gtttacactc
     1561 tttttattag cgacagccga aggagggttt taacttgggg ttcagtattt cgttcaaaaa
     1621 gggaacaaag aatacaagca tttctcataa taatcgtgag ttaactgata gccaaaaaat
     1681 caatgactgg cataagcata ttgatttcac aaaatcggat gaaaatatct atttagaaca
     1741 aacaaatatt cgtgaaaaat atgaagaatt attcggtgaa gccgtagaaa aatataatgc
     1801 aaagcagaaa agagccgata gaaaaatcga ggactattta gcaaaggttc gcaaggataa
     1861 aaaattggaa ccacagcgag aatttatcgt gcaaattggt actcttgatg attttcgtac
     1921 tactcgtgat gatggttctt ctactggcat atcggaacaa caagcagaac aaaatcgagt
     1981 gattgccaac aaaattttag ttgagtattt caaagaattt aaagaacgga atcctaattt
     2041 atccgtctac aatgctgtta ttcataatga cgaagtaagt ccgcacctgc atttgaatat
     2101 tgttcctgtt gctgaagggt ataaacgggg tgttcaaaag caaccaagtt ttaacaaagc
     2161 cttgcaacag cagggtttac gagcagataa agagaatggt cgagtgattt ggaataattt
     2221 taggaatcag gaagttgagt caattgaacg tttgatggca gattttggtt gggagcgtga
     2281 gttagtcggt actaacaaaa tcaaagatgt tcacgaatat aaagaaatca tgagcgagat
     2341 ttcagaattg cgtcaaacgg ccgtaaaaga gcgtgagagc gtttctgatg agttgaggta
     2401 tatttctagg caaagagaag aaaatgagcg agaaaaggct ctggtggctt ctgagagagt
     2461 gaagattgaa gaagagaaga aaaatatgct gaatgtaaaa aaagagatgg cggtcatttt
     2521 ccaaaaagat attgttcctt tagaaagttt caagaggctt cctgatggtt cgtatcattt
     2581 atctgggaat gattttgttg atttgtatca acgagctacg agagcaacaa atgccaagag
     2641 aaatgctgat aacatgagtg agcaatattt acagatgctt gagcaaaata cagaattaaa
     2701 tgagtatgta gctacattgg aagaagagcg tcatttgtct ggtagaaaac aattagcaga
     2761 tttacaagtg gaaaataaaa agctgaaaga agaaaatcgc tctttacgcc agcgtttaga
     2821 gcgattaaaa aacgcatttc aaaaatcgat cactcgtttg tctatccgtt ttggtcttgc
     2881 agaaaaggat atggggcttt ctgaggaatt agaagtgtta gagcaggaga aaaccttatt
     2941 ttatcgtcaa aacgtctcac agcgtaaatt agagcgttct gaagatgaga tcgagtggta
     3001 gttacgatgt gcagtcaacg gtaccggagg cggtttgtgc cgaggataag gagttgacgg
     3061 ctaaaccact agcctattaa gctgacattt gctaaaaaat ggccagtcca ttttttggcc
     3121 aacctagcgt tagcgaagtt tgggggcgcc cttttcaaag ggtgcggttt tattttttgg
     3181 atatttgcat agctaaagag aagtgctatt attgagttag caaacaaatg aactgaaaaa
     3241 agagtaaaaa aatagtcgag caacgctacc aacgttctcg acctttacgg aaactaatcg
     3301 cactagctcc gtaacttctt aatcattata cgaatatttt tagatttctt caagactaga
     3361 gattttttgg taatgaattt ttaagagtta cgtgaacttt tgaaaattct ttccagaagt
     3421 ctctttttct ttgaggagga acaaaatttg agtaaacgtg gcacgatcgt gaatgagtgg
     3481 gaaaaactta accgcatttc taacaggcgg ttaaagtatc aaagtttgac ccttccctta
     3541 aaaatgcagt ggtcaattga ccgaattacc atagtcggaa aactgaaaga aaatatttat
     3601 tatcacactc caaatgatgt gttgatttta aattttgaac agcttatgcg tttgaacgaa
     3661 ggcaatggtt atttaaaagc tgttgggaat aatgggtggc aattattaga ccaacacgag
     3721 gaaaatatag cttatattga gattcttaaa tttcatgaag gaaaagggcg gattgacttt
     3781 aatcctaata aaatcaatca atttttatca ggttccatga aaaatttcat tcatgattta
     3841 tttctagaac ctcatttttc acgtgcggat attgcttgcg atattgtaga tattcccgat
     3901 gactttgtta gtcagtatcg tgtagttgat cctgtgtctt ttaaaccaat ttatgggcgt
     3961 tctggtaagt tagaaacggc atattggggt agtcgtgcca gtgaacgaca aattcgaatg
     4021 tacaataaaa aattggaaca agaaagaaaa cgtaaaattg ttccgccgga aataacgaca
     4081 tggtggcgac tagaattgca gttacgaagg ggaaaagcaa ctgattggca tgagatggtt
     4141 catgaaagt
//
LOCUS       DACGLI010000118         4054 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.125, whole genome shotgun sequence.
ACCESSION   DACGLI010000118 DACGLI010000000
VERSION     DACGLI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.125"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            96..251
                     /locus_tag="IXT22_002840"
                     /pseudo
     CDS             96..251
                     /locus_tag="IXT22_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            270..1547
                     /locus_tag="IXT22_002841"
     CDS             270..1547
                     /locus_tag="IXT22_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4864143.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1557..2213
                     /locus_tag="IXT22_002842"
     CDS             1557..2213
                     /locus_tag="IXT22_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4864144.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2213..3589
                     /locus_tag="IXT22_002843"
     CDS             2213..3589
                     /locus_tag="IXT22_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4864145.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3719..>4054
                     /locus_tag="IXT22_002844"
     CDS             3719..>4054
                     /locus_tag="IXT22_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864146.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIA"
BASE COUNT         1614 a          445 c          710 g         1285 t
ORIGIN      
        1 cttcgttgac gtcttggcat gaaaaatcct ccagtgtgtt ttttattatt ctacacacct
       61 tattttttct gtctagtcta gtgtagccga ttcaggataa ggataagtgt attaattgtg
      121 gaaaatgtaa aaaagtttgc caaatgaata aagattcagt tgagaattgc aatcatctgg
      181 agtgtatcag atgtggacga tgtaaaaatg cttgtccagt ggatgcaatt agttatggag
      241 taagaaaata gagaggagta gttaggaaag tgataaaaaa tgctatagca tatattacaa
      301 gaaagaaaaa tagaacttta ataattttta tcatattaac tatagttctt tcttgcttgt
      361 attcttgttt aacaataatg aaatcaagca atgaaataga aaaggcttta tatgaaagtt
      421 ctaattcttc aatatcaata acaaaaaaag atggtaaata ttttaatgtt aatcaattta
      481 aagatattga aaaattaaaa gaaattgaag aaaaaataat tcaatatgat ggattagcaa
      541 aactaaaaga tgctaaagta gttagcggag aacaaagaat aaatagagaa gatttatctg
      601 acgaatttaa gaatgttgtt tcactcgaag ctacaaataa tactaaaaga aatattttat
      661 ttagtagtgg agtatttaca attaaagaag gtaaaaatat agaagaaaat gataagaatt
      721 caattattgt tcatgaagaa tttgctaaac aaaacaatct aaaattaggt gatgaagttg
      781 atcttgaatt actagatatt gaaaaaagtg gaaaaataaa aagtcataaa tttaaaatta
      841 tagggatctt ttctggtaaa aaacaggaaa catatacagg attatcttct gattttagtg
      901 aaaatatggt gtttgtagat tattcaacaa gccaagagat attaaataat tcagaaaata
      961 atgaaattgc aaataaaatt ttaatgtatt ctggtagtgc agaatctaca gacttagcct
     1021 taaacaaatt gaaagagctt aaaattgatg agtcaaagta ttttgttgaa aaagattcta
     1081 atgcgtttga agagtcttta gagtcagtga gtggaataaa atatataata aaagtaatga
     1141 cttattctat tatgttaggt gggatggttg ttctttcatt aatcttgatt ctatggttaa
     1201 gggaaagaat ttatgaaata ggtatattct tatctattgg aacatctaag atacaaatta
     1261 taatgcaatt tatattcgag ttaatattca tatcgatacc aagtataata tcttccttat
     1321 ttttaggaaa tgtattacta aaagtaattg tagatggatt cattaactca gaggattcaa
     1381 tgatttccgg tggaagttta ataaataata gtagttttat gtcaaatata acaacacttg
     1441 gacaaagtta tttaatatta ataagtatta ttgttttatc agttgtattt gcttcttcat
     1501 taatgttaat caagaagcct aaagaaatct tatcaaaaat aagttaggag aaaataatgg
     1561 atatattaga aataaagaat gtagcatata gttatgcaaa ttctaaagaa aaagttttgt
     1621 caggagtaaa tcaaaaattt gaacttggga agttttatgc gatagtagga aagtcaggaa
     1681 caggaaaatc tacacttctt tccttacttg ctggacttga taaacctcaa acaggaaaaa
     1741 tattgtttaa gaatgaagat atacaaaata aaggatatag taatcataga aaaaataata
     1801 tatctttagt atttcaaaac tataatttaa tagattattt atcaccaatt gaaaatatta
     1861 gattagtaaa taaatcagca gatgaaagta tcttgtttga actaggttta gataaaaaac
     1921 aaataaaaag aaatgttatg aaattatctg gtggacagca acaaagagta gctattgcta
     1981 gagcattggt atcagatgct ccaataatac tagctgatga gcctactggt aatctagaca
     2041 gtgttactgc tggagaaata attaatatat taaagacatt agctaaagat agaaataaat
     2101 gtgtaatagt tgtaacacat agtaaggaag tagcagattc tgcggatatc attttagaac
     2161 taagtggtaa aaagttgaaa aaagtaaata aaatgaattt ggaggttgaa taatgataaa
     2221 aaatgcattt gcttatgtaa ctagaaaaag tttaaaatca ttaattatca tattagttat
     2281 tttatctatg tcaactttaa gtctcattag tttatctatt aaagatgcta cggacagagc
     2341 ttcaaaagaa acatttgcta atataacaaa tagtttttct atggagataa atagacaagt
     2401 aaatccagga acacctagag gtgggggaaa tgtaaaaggt gaagatatta aaaagatatc
     2461 tcaaacagat agtatagact cctatgtaaa aagaataaac agtgttgcag atttagttga
     2521 ttatgatatt attgaaactc aagagactct tgcgaatcaa tcacctgaaa gagcaaagaa
     2581 ttttaaaaga acagttatgt taactggggt taacgactca acaaaagaaa caaaatttgt
     2641 atcagaagca tataaattag tagaaggaaa gcatttagaa aatgaagata aaaataaaat
     2701 cttaatgcat aaagatttag ctgaaaaaaa taaccttaaa gttggagata agataaaaat
     2761 aaaatctaat ttatttgatg ctgataatga gaaaggtgca gatgaaacag tagaagtaga
     2821 aattaaaggt ctattcgatg ggcataatag cggtgtagta agtgcagcac aagaactata
     2881 cgaaaataca ttaatcactg atattcatac agctgctaaa gtttatggta ataccgaaga
     2941 tacagctgta taccaagatg caacattctt tgtaaaaggt gataagaatc ttgatagtgt
     3001 aataaaagat cttgggaaat tagatataaa ttggagagaa tataatttga ttaaaagttc
     3061 atcaaattac cctgcattac aacaatctat atcaggtatt tactcaattt caaataaatt
     3121 attttttggc tcattaatat ttgcaggagt tgtagtttca ttattattat tcttatggat
     3181 gaatgctaga aagaaagaaa tagcagtatt actatcatta ggtatatcaa aattagaaat
     3241 ttttggtcaa ttcctaattg agatggtatt tatatcaatc cccgcattcg ttggttccta
     3301 tttcttagct caatatacag ctgacaagct tgggaataat atattgaata aggttactgg
     3361 tgatatagct aaacaaatag ctaaacaatc tgcatctagc caattaggtg gtggggcaga
     3421 agctgaagga tttaacaaga cattatcaag tttagatatc aatgtattac ctaaattcat
     3481 gatttatgta gttatattta tgagtttagt acttcttgta tcattgatta tttcttcatt
     3541 caatatatta agaaggaatc caaaagaatt attaattgac aataattaaa attttcggtg
     3601 ctttttagca ccaaaaatga gagtgtaata taaaccgtgt aagtaaccat caatcctagg
     3661 cgggtggttg cttcacggtt tttatttttc taaaataaga tcaagaggtg attacacgat
     3721 ggctagaaag aaaagaaatc ctgatgctga gaagttagct gaatccattt tgaatactta
     3781 tcaacccgaa tctgtagagg atatgcaaga tgttttaaaa gatgtgtttg gtcccttatt
     3841 tgaaaaaatg cttcaaggag aattgaataa ccatttaggg tatgacgccc attctaaaga
     3901 gccaaagaaa catgacaatc gacgaaacgg ttatggcaat aagacgctta aaacgagctt
     3961 tggtaaagta aacattgatg ttcccagaga ccgggaggct tcttttgaac ctgagttgat
     4021 tcctaataga aaacgagatg tctccgacat cgca
//
LOCUS       DACGLI010000119         3889 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.126, whole genome shotgun sequence.
ACCESSION   DACGLI010000119 DACGLI010000000
VERSION     DACGLI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.126"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..316
                     /locus_tag="IXT22_002845"
     CDS             <1..316
                     /locus_tag="IXT22_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HAQ4864147.1"
                     /translation="LTIPGAMSPTEIFKMFEMGADIVKVFPANCLGPEYFNQVQAPLG
                     SLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKSAVHQLNYERLMELAESFIDSLR
                     VE"
     gene            complement(710..1717)
                     /locus_tag="IXT22_002846"
     CDS             complement(710..1717)
                     /locus_tag="IXT22_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4864148.1"
                     /translation="MVTIRDIAKKSGYSTATISRLFKGDESLSITSDTKNKIIVTAKS
                     LGYDLTKIKTTLYKIAILFWISEEQLKKDVYYQHVKDDLKNYSKKANLDLIFISKNDG
                     VKSIPDDITGFIAIGQLTKKELYYLNQKGYKGVIRGINPLPEHFDTVEPDFHEMARQA
                     INYFINEGFTKIGFIGGNFFNLETGKEEIDSREYAFRYHLEKSGLLNEKYIFSQGSFT
                     VDEGYQLTLKMKAELNEDMPEACFIPSDTIAAGVLQGCHELGINIPKDMAVISINDDD
                     IAKFVAPPLTTFKIDIEEIAKTCVDLLSDQLVYSRDISKKTLIGAKLTVRKSFIPKEE
                     V"
     gene            2184..3590
                     /gene="lacG"
                     /locus_tag="IXT22_002847"
     CDS             2184..3590
                     /gene="lacG"
                     /locus_tag="IXT22_002847"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4864149.1"
                     /translation="MNYKTLPEDFIMGGATAAYQAEGSTKEGGKGQVAWDTFLVEKGR
                     YTADPASDFYNQYPVDAELCKKFKIDSIRMSIAWSRIFPKGYGEVNQTGVEYYHKVFA
                     ELNKHGIIPFVTLHHFDTPKELFDNGDFLNRENVEHFVNYAQFCFDEFSEVHYWSTFN
                     EIYPVASNQYLIGSFPPEVQFDIEKTVTCLHNMMYAHAKTVNIFKDGGYKGEIGVVHS
                     LETKYPASDKEEDKHAAKLDDALSIKFLLDATYLGYYSDETMAHINEILAANGQSADI
                     DSNDFREMKKAANRNDFLGINNYGSHWVKEYKGESTLHYNTTGEKGSQVYCIKGIGER
                     IVREDLPKTDWDWIIYPKGLYDLLVRIQDEYPNYNKIYITENGLGYKDNFEDGIILDD
                     DRIDYLRQHFNAISDAIKMGVNVKGYFIWSLMDVFSWVNGYTKRYGLFYVDFDTQKRY
                     PKESAYWYKFVSETKTII"
     gene            3613..>3889
                     /locus_tag="IXT22_002848"
     CDS             3613..>3889
                     /locus_tag="IXT22_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4864150.1"
                     /translation="MDRKELQLLGFEIVAYAGDARSSLLTVLKEVREGNFDNVERLLA
                     DADENLTLAHNSQTKCLAEEASGNEMEVGVIFIHGQDHLMTTILLREL"
BASE COUNT         1282 a          579 c          757 g         1271 t
ORIGIN      
        1 tctaacaatt cctggggcca tgtcgcccac agagatattc aaaatgtttg agatgggtgc
       61 tgatattgtt aaggtgttcc ccgccaactg tcttggaccg gaatatttca atcaagtgca
      121 agccccttta ggaagtttac ctttgatggc tgtaggaggg gtagatcaga ctaatgcaca
      181 aaactatttg aacaatggag cctcttatgt aggaattggt tcaaaatttt ttgaaaaaag
      241 tgctgttcac caactaaatt acgagaggct aatggagttg gctgaatctt ttatagatag
      301 tttaagagtt gaatagaacc catttgcgga atacaacttg ttttataata tggcgttatc
      361 tgtataaaac atagtatcac agtgaatgag attgaactgg tagattgatt tttcgaccag
      421 ttctttttgc gcgctctgat gcttgatata ttcccaacga gataaaaaat cccccaagat
      481 actaagatga agcgtttatc caacctcata cttagataaa aaggaggaaa tgttctgaat
      541 gataaacaaa aattagcgcg cacaatttgg cgatgaaaaa atcatattgt atttacgtca
      601 aaatatcacc atcaaattat ttatggaaaa cataataggc ataaacccga ttgctcggct
      661 actatgtgga cacaattata gttttaaaga taagtttcaa ttacttattt tacacctctt
      721 ctttagggat aaaacttttc ctaacggtca attttgcgcc gattaatgtt ttctttgata
      781 tgtcccgcga atataccagt tgatcactta ataaatctac acaggtttta gctatctctt
      841 cgatatctat cttaaaagtt gtaagtggtg gtgcaacgaa ttttgcgatg tcgtcatcat
      901 taatacttat tactgccata tctttaggga tgttaatacc caattcatgg cagccctgaa
      961 gaacgccggc agctatagtg tcagatggta tgaaacatgc ctcgggcata tcttcattta
     1021 actcagcttt cattttaaga gttaattgat acccttcgtc aacagtaaat gatccttggg
     1081 agaaaatata cttttcattg agtagtccgc tcttttctaa atgatatcgg aaggcatatt
     1141 cacggctatc aatctcttct ttacccgttt ctaggttaaa gaaatttcct ccaataaatc
     1201 caatttttgt gaaaccttca ttaataaagt agttaattgc ttgtctggcc atttcgtgga
     1261 aatcaggttc tacagtatcg aagtgttcag gtaatgggtt tattcctcgg attaccccct
     1321 tatacccttt ttgatttaag tagtacaatt ccttttttgt caattgtcct attgcgataa
     1381 atccagtaat atcgtcagga atgcttttta caccatcgtt tttagagatg aaaatcaaat
     1441 ctagattagc ttttttacta taatttttca aatcatcttt gacatgttga tagtagacat
     1501 ccttttttaa ctgttcctct gagatccaaa aaagaatggc aatcttgtac agagtagtct
     1561 taatttttgt cagatcatat cctaaagatt tggctgtaac gattattttg tttttagtat
     1621 cagatgtaat agagagtgac tcatcacctt taaaaagtct tgatatagta gccgttgagt
     1681 aaccagattt ttttgcaata tctctaatag taaccattgt tcatcctcct agggatataa
     1741 taatcctttt ctttgttaaa gtaaatcgaa actgctcttt tagtaactta aattactttt
     1801 tctagcagga aacgaaactc tgatatcagc agagagccta atccattaac agagaagatt
     1861 gaatcgataa tggatagcca cttggagaat gattagtagg tgggattgat tttagtggga
     1921 atcagtccgt tttcttgttt cgtgtaaatt aaattagtaa aaagataaat ttattttaca
     1981 aaaaaacgtt tacaaaacgg tttttgaatg gtatatttat tttacatcaa gggatataag
     2041 tgcttgtata tcgcaataaa atagatattc gaggtcggtt tttcgttgtg taaaaaaatt
     2101 tacttataca tgttaaaatt atgctgaggt gatttatggg ttattggcat attgatcaaa
     2161 ctaattttca aggagagatt aaaatgaatt ataaaacttt accagaagac tttattatgg
     2221 gaggagctac ggcagcttat caagcagaag gctctacaaa agaaggtgga aaagggcaag
     2281 tagcgtggga tactttcctt gtagaaaagg gacgctatac tgctgatcca gctagtgatt
     2341 tttataatca atatccagtt gatgctgaat tatgcaaaaa atttaaaatt gatagtatta
     2401 ggatgtctat tgcatggagc cgtatttttc caaaaggcta tggggaagtg aaccaaacag
     2461 gagtggaata ttatcataag gtatttgctg aattgaataa gcatggtatt attccttttg
     2521 taactcttca tcattttgat acccctaaag aactatttga taatggagat tttttaaatc
     2581 gagaaaatgt tgaacatttc gtaaactatg cacagttctg tttcgatgaa ttttctgagg
     2641 ttcattattg gagtacattt aatgagattt atccagttgc ttcaaatcaa tatttgatcg
     2701 gatcgtttcc tccagaagtt caatttgata tagagaagac tgtaacttgt ttacacaaca
     2761 tgatgtatgc gcacgcaaag acagtaaaca tttttaaaga tggtggatat aaaggggaaa
     2821 ttggtgttgt tcactcgcta gagacaaaat atccagcaag tgacaaagaa gaagataagc
     2881 atgctgcgaa attagatgat gcgttatcaa ttaagttctt attagatgct acttatttag
     2941 ggtattactc agatgaaaca atggcacata ttaatgagat tttagcagca aatgggcaat
     3001 ctgcagatat tgattctaat gattttagag agatgaaaaa agcagcaaat cgaaatgatt
     3061 ttcttggtat caataactat ggtagccatt gggttaaaga gtacaaagga gaaagcacac
     3121 ttcactacaa cactaccgga gaaaaaggta gccaagtcta ttgcattaaa gggattggcg
     3181 agagaatcgt gcgtgaggat cttccgaaaa ccgattggga ttggatcatt tatccaaaag
     3241 ggttatatga tttacttgta cgaatccaag acgaatatcc aaattataat aaaatataca
     3301 ttactgaaaa cgggctaggg tataaggata attttgaaga tgggattatt ctagatgatg
     3361 atcgaatcga ttatttacgc cagcatttta atgcgatttc cgatgctatc aaaatgggag
     3421 ttaatgtaaa ggggtatttc atttggtcat taatggatgt tttctcttgg gttaatggat
     3481 acactaagcg ttatggacta ttctatgtag atttcgatac acaaaaaaga tatccgaaag
     3541 agtctgcata ttggtataaa tttgttagcg aaacaaaaac gataatataa aaatagttag
     3601 gagggcaagg aaatggatag gaaagaattg caattattag gatttgaaat tgttgcttat
     3661 gcaggagatg ccagaagttc attattaaca gtgttgaagg aagtgagaga aggtaatttt
     3721 gataatgttg aacgattatt agcggatgct gatgaaaatt taaccttagc gcataactca
     3781 caaacgaaat gtttagctga agaagcgtca gggaacgaaa tggaagtagg cgtaattttt
     3841 attcatgggc aagaccattt aatgacaacg attctattaa gagaactta
//
LOCUS       DACGLI010000120         3700 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.127, whole genome shotgun sequence.
ACCESSION   DACGLI010000120 DACGLI010000000
VERSION     DACGLI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.127"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(75..1169)
                     /locus_tag="IXT22_002849"
     CDS             complement(75..1169)
                     /locus_tag="IXT22_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4864151.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1358..2119
                     /locus_tag="IXT22_002850"
     CDS             1358..2119
                     /locus_tag="IXT22_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4864152.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="IXT22_002851"
     CDS             complement(2234..2674)
                     /gene="fabZ"
                     /locus_tag="IXT22_002851"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4864153.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            2894..3649
                     /gene="fabI"
                     /locus_tag="IXT22_002852"
     CDS             2894..3649
                     /gene="fabI"
                     /locus_tag="IXT22_002852"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAQ4864154.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
BASE COUNT         1187 a          721 c          653 g         1139 t
ORIGIN      
        1 ctataaaaaa acaaaataaa aaagcagaaa taactggcta tttctagcgg attatttctg
       61 caataactaa ttatctattt tttattttca attaatttaa agcttgacca tggtttcaaa
      121 aagtcaagga ggaataattc gtcatcggag attcttccta caacattgac acgtccgtcg
      181 tttttcatat ccttcaaggc gatttgtgtt tctcctttgt attgaccgta cccttcattg
      241 tcaatcagta catccccatg atgcatatct cgcgtattat gaggcgggaa atctttatct
      301 ttgtagtata cacgagtcat cgttgaacga aggatatatt ctgagcgatc ccctcgataa
      361 ctatgaaggt tatcaaacaa gcagattcgt tcgttttctg taataccttc ttccgtatct
      421 actttcaatg ttggataatc cgcgttaaat gcttctgcca tttctttcaa ttcttcttca
      481 cttgcgtacg catttccaat agaaatatca tcaatcaatc ctgtaaggat taaatgcttc
      541 acttgtgtcg caatttcaag atctcggtgg tcttccagcg tgcacaagcc atcttgcgta
      601 ggccaagggc caaactcagc agattgcgaa ttgacgaatg ccatcgtatt caaattatat
      661 tttctgaatt tttctgaaca aaaaacaaag tgttcgtatc ctaaaccaga gtatcgatga
      721 ggataaaaat tatgagaacc taataaatta tccgtgtttg gcgaataact catgatgttg
      781 tcaacgtaat tcgtgcccga actcatattg atctcgattt tgataccaaa aggattgcgc
      841 gtcatttttg cttcttctgc tcctgtgaat ccgatatcta agcggacccc gtaggcaccc
      901 atcttatgga aaaaagataa gtcatcgtaa gaaatctcca actgttcaaa taacgctgga
      961 ttgatatcaa ccattacttc catgcctagg ctattcgcgt aatcaactac ttctttaaat
     1021 tctgaaagaa ctttttcttt atcatcattg atctgcagca aactggtaaa aacccgttta
     1081 tacccatact tatgagctaa atccaagtac gctttgtcct tttcaaatgt tgaccgttct
     1141 ggataaatcg agattcctaa ttttcccata ttaccatttc ctcctgcatc ttttcgtttt
     1201 tgtatccact tacattatag caaacacaaa gtaaatggtc tacacctttt ctttttcttt
     1261 taaaataaat gataaattcc aataatttaa gtaggtattt tccctctatt ttgttatcat
     1321 taaagataac aaaatagtaa attggaaagg aacagttatg aagaaaaata aagttatttt
     1381 aagtattagt ttagcagcag cattgctgtt tgctgctggt tgttctgcaa acaacacgac
     1441 ttcttctagt tcgtctacag aaagttcaaa aagtacatct actgcggaaa gcacgactgc
     1501 cagtagcgtc gatttgaacg cattggaatt accacaattg acgaaagatg tcgccgaaaa
     1561 tgaagatctg gtcgaaatgg tgacgaataa aggcacaatc aaaatcaaat tatttcccga
     1621 acacgcacca aaagcggttg aaaactttat gacacatgca aaagacggtt actacaacgg
     1681 actgactttc catcgcgtca tcaaagattt catgatccaa ggtggcgatc ctaaaggcga
     1741 tggcactgga ggggaaagca tttggggaga aggatttgaa acagagatca acaaccacct
     1801 ttataatata agaggtgcgt tatctatggc tcgctcacaa gatcctaaca gtaacggcag
     1861 ccagttcttt atcgttcaaa atacagatga tatgcatgat ggtcttttaa aagacgacta
     1921 tcctcaagca atcatcgacg cttataaaaa cggcggttat ccttcactag atggccatta
     1981 tactgtcttc ggccaagtga ttgaaggaat ggatgtcgtg gatgctattg caaatatcga
     2041 aacagatagt tcagacaaac caaaagaaga agtaaaaatc gataaaatca atatactgca
     2101 agaagcaaaa caaaaataaa aaaataacgt ctgaatcctg catagatgac aacgtatgct
     2161 aggattcagg cgtcttcttt ttacataaaa agcaagtaag cttccttttg ttttgctata
     2221 tcaggtttta tagtcaagca ttttggttga cgatgaacgt gaactcgcac tcacagactt
     2281 ttttatcatc tacatatgct gcagataacg ctgtaccgac tgatcccttc attttggtga
     2341 tttcaaaatg acatttcagc acatctcctg gaacaacttt ttgacggaat ttggccttat
     2401 tgatcccacc gatataagct ctttttccta gaaactcttc tgattttagg ataagtatcg
     2461 aacctgcttg tgccagtgtt tctagaatca acgcacccgg catcactgga ttgtcaggaa
     2521 agtgaccttg gaaaaaatct tcattgattg ttacattttt tgtcgcaacg atcttttttc
     2581 ctggttctaa agtatctaca taatcaatat aacaaatagg ataacgatta ggaatcaatt
     2641 ccattacttc agtagcagat aatacgtaag acataattaa actccttctt tcaggcaatt
     2701 gccattttca ttactttgac tatcaaagta tcatattcct aaatatttag caatcttttt
     2761 ttaatttaag aaaaaatagt ttgacaatca aaacattttg actaataatt aagaaatcaa
     2821 gaagttattt tagctattat tctctatttt tttacgacta tcaaattttt atcagaaaca
     2881 aaggagagtc attatgtcat ttctagaagg aaaaaaaatc gtcattatgg gcgtcgctaa
     2941 caaaaaaagc attgcttggg gttgtgctga agcaatgttg aaacaagggg cagaaattat
     3001 ctatacttac caaaatgaac gaatgaaaaa atcattagtc aaattggtcg gcgaagaagc
     3061 attcactgta gaatgtgatg tttctagcga cgaaagcatc gaaaaagcaa tgaatgccat
     3121 cggtgaatat gctggggaga tccacggcct tgtccatgca gttgcttacg ccaacaaaga
     3181 agaattgtcc ggaaatgtgt ctgatatttc cagagacggc tatcaattag ctcaagatat
     3241 cagcagctac tctttaattg ctgtatcaaa atacgcacaa ccgtttcttg caccaaacag
     3301 cgggatcgtt agcatgactt atctaggttc agaacgcgca atcccgaatt ataacatgat
     3361 gggtattgcg aaagcttctc ttgaagctgc tatccgttat ttggcagctg agttctcgcc
     3421 taaaggaatt cgggtcaatg gaatctcagc tggggcaatc aaaacattag ctgtcacagg
     3481 tgttaaagac tatcaaaaac tgatccagtt atctgaatct cgtacgcctg atcagcaagg
     3541 tgtgacgatc gaagaagtcg gtaatgcttg tgctttctta atcagcccac tttccagcgg
     3601 aatcatcggt gatattatct acgttgacaa aggtgtccat ctttcataaa cttttgttgc
     3661 attctttaaa gtaaaacata taaaaatcag gaaaaaactt
//
LOCUS       DACGLI010000121         3634 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.128, whole genome shotgun sequence.
ACCESSION   DACGLI010000121 DACGLI010000000
VERSION     DACGLI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.128"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(133..717)
                     /locus_tag="IXT22_002853"
     CDS             complement(133..717)
                     /locus_tag="IXT22_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864155.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(928..1131)
                     /locus_tag="IXT22_002854"
     CDS             complement(928..1131)
                     /locus_tag="IXT22_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864156.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1141..1563)
                     /locus_tag="IXT22_002855"
     CDS             complement(1141..1563)
                     /locus_tag="IXT22_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864157.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1801..2415
                     /locus_tag="IXT22_002856"
     CDS             1801..2415
                     /locus_tag="IXT22_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864158.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2580..3404)
                     /locus_tag="IXT22_002857"
     CDS             complement(2580..3404)
                     /locus_tag="IXT22_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864159.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
BASE COUNT         1203 a          635 c          517 g         1279 t
ORIGIN      
        1 taatattaac aaatgaataa aatccttaca acatttgaga ataagttatc agtagacact
       61 tacaaaaaat tctcatacta ttgtcacttt tctagataaa tggcaaaaat tttcagcatt
      121 aaatgacaaa aactaatgag aatttgtctt tccatttttc tcctccattt ttgccaaata
      181 acgataaatg gtggttcttg agacgttcca ccgttccgca atagtcttaa taggtgtacc
      241 gctatccact aaagtcttca gtaattccaa atcttgttca gacaattttt caggacgacc
      301 accaaaccgt cctcttgcac gagcagctgc tcgtcctgct gcggatcgtt ccaggatcaa
      361 attacgctca aattctgcaa atgccgcaaa caaatgaaac atgagctgtc ctgtagaact
      421 tgatttgtcc atcgtaatat tttcttgaat actatgaaaa ctcacaccac gctcattcag
      481 tcgattgacg attgaaatca aatcttccat atttctacct aaacgatcta agcgccaaac
      541 gacaagtgta tcgccagagc gaacaaaatc aatggccatt tctaatcctg gtcgattact
      601 ttttgcccca ctcatatgat cagtaaaaat tttttcacaa ccaaatttat ttaggctgtc
      661 ttcttgtaaa tccaaatttt gtaaaccagt agatacccgg gcgtatccta ttttcaaaaa
      721 aatcactcct tcattaattt tattgtaaca taactttatc catatagttt aactgaacat
      781 agatattgtt atgggtttat gaacatgaaa tgaattgttt ttttgaaaaa taaagcaaaa
      841 aaagaaagtg tccagaaatg ggtgatttta tgaacacttt caattagaaa aaaagaatgt
      901 cgactagaca ctcttttttt aaaatcatta tttttctttt tgatatgttt tttggtctct
      961 tttttttctt ttttcttcag aatcttctag attagaaatt gatttttgaa ttttttgtgt
     1021 ctcctgtaaa gttcgctgaa cttgtaaagc tgattcttct ttcggtaaat taattttact
     1081 tagaatatcg ctatcttgat aaaaatttgg tgtgttcaca aattctggca taaaaaatcc
     1141 ctactttcta gttaaggttc ctgaataagt cgcaatccaa ttgtttccag ctgatttata
     1201 actttgtaaa tacaattttc catagtacca ataaccattt cttttttctt tccaattccg
     1261 tgattgagga ggtctagaag gccaaccaac tttatcaaaa atcatcgttc ctgtcactcg
     1321 tatcgtttta gaagctgcta gagcaagtaa tggagaaact attaaataat tttcagtaac
     1381 agttaagtcg ttagttgggt taccaatggc tattccgtcc ctatctaaag gagttaattc
     1441 ttggttatta tctactacag tagttggttc atttgtacta tcagcaaatg taggaattgt
     1501 agttccagtt acactaattc caatagttaa aatacctaaa gataaaataa acttattttt
     1561 cattgtctat cacctcgaaa tcaaaactaa gaaaacgttt tcttaataaa tcttaacaga
     1621 taaatcaagt tatatactag aaaattcata aaatatattt ttaatgtcat aatcgtttaa
     1681 attttcttga ttgacattta tttacaaaaa atattgccat ttaaaaagaa aagtgacata
     1741 tggcttcctc gtgtatgatt agggtgtatt ttaaatagtt gcagaaagta ggtaaaagtt
     1801 ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg ccagattgaa
     1861 gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg cgcaacgatt
     1921 actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga tatttttatt
     1981 gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc agtcaattac
     2041 ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc tgaagcaatt
     2101 ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt ggccatgatc
     2161 gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa gatcgcaaaa
     2221 gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa agatccccaa
     2281 cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc gattgctaag
     2341 attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa agacagcatg
     2401 gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta atttcctaca
     2461 tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata aaattccaac
     2521 aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac ttatttacgt
     2581 taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc cttattatct
     2641 tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact aattcctata
     2701 gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat ttgagattta
     2761 tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata cataaagcta
     2821 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     2881 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     2941 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     3001 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     3061 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     3121 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     3181 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     3241 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     3301 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     3361 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     3421 aaatcagcta atttttcttt agaataaaaa aaacatttat atcagaatca ataaattcta
     3481 ttttttttat tactatatcg tcatcattat cttgaccatt tatgtttatt gttccctgag
     3541 tggggagtac ttctttcaaa ttcaagttaa atttatattc cattacttct cctccaatat
     3601 ataaaaatta cttaactgta tccaaattta atat
//
LOCUS       DACGLI010000122         3465 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.129, whole genome shotgun sequence.
ACCESSION   DACGLI010000122 DACGLI010000000
VERSION     DACGLI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.129"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(517..858)
                     /locus_tag="IXT22_002858"
     CDS             complement(517..858)
                     /locus_tag="IXT22_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4864160.1"
                     /translation="MKPNEIVTVYAAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
     gene            complement(848..1129)
                     /locus_tag="IXT22_002859"
     CDS             complement(848..1129)
                     /locus_tag="IXT22_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAQ4864161.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDKPVDVLDTDEKLEEWFNEA"
     gene            complement(1236..1820)
                     /locus_tag="IXT22_002860"
     CDS             complement(1236..1820)
                     /locus_tag="IXT22_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864162.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            complement(1837..2076)
                     /locus_tag="IXT22_002861"
     CDS             complement(1837..2076)
                     /locus_tag="IXT22_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864163.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            complement(2095..2343)
                     /locus_tag="IXT22_002862"
     CDS             complement(2095..2343)
                     /locus_tag="IXT22_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864164.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            complement(2358..2924)
                     /locus_tag="IXT22_002863"
     CDS             complement(2358..2924)
                     /locus_tag="IXT22_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864165.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            complement(2925..>3465)
                     /locus_tag="IXT22_002864"
     CDS             complement(2925..>3465)
                     /locus_tag="IXT22_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864166.1"
                     /translation="ERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIYLI
                     NKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIEDVM
                     KFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDFIK
                     GYRLLLENYGINLEEESVK"
BASE COUNT          968 a          805 c          376 g         1316 t
ORIGIN      
        1 cgaccgctcg ctacgcgacc gttcgttcgt cttttcctcc gtgggactca cccaccgcaa
       61 gcggttggtt gagttgtggc tcctattcaa aattcactaa tatgttattt ttgttttcta
      121 ttcaagtggg taacgttcgt ttgcaagcaa actctctcta tgtaacttgc cagttacatc
      181 agtggtaacg ctacgtcgca agcgacttgc tctaatgaaa ctaccgtttc attctgcctg
      241 ttcgttcgta gcaagctact tcactcactg tatccgtctg aattattgtt atttattact
      301 attcaatatc cgtcagtcat tttatttatt tacatacatt aaatataaaa atgtatctta
      361 taattcgtat attactaatt atcactattt aacaatactt aatattttct taatttttat
      421 aatcacgtat atatttacgt gtattttaat atacataaat acgtttatat aaacgtatat
      481 cttaatatac atataaacaa aaaaagaaaa gccttgttag acttttcttt gtaatctctc
      541 gataaaccta tttagctttt tcgtatcaat agctgatagc ataccaacct ttttaaatga
      601 tatgttctct cggcttttgg gaatagcctt taaagaccct acgtcaatcc atgattgctt
      661 ctttagacct actttttccc attctgcaat aggaaaatac actctcttta tttggtctga
      721 tttattctca tattgacttg tgattccaaa aaattctact ctatcttctt tatcactaac
      781 caccaaaata ggtcttcttt taccaccatt tttatctgta aatgcagcat agaccgttac
      841 tatctcatta ggcttcattg aaccactctt ctaacttttc atctgtatct agaacatcaa
      901 ctggcttatc catagttagc tgttgcaatc tgattccttg cttttcctct tcgcttagct
      961 ttatctctac tggaaactca cctctagcga ccacttgctt ataaaggatt gtgattgctg
     1021 ttgttggatt taaccctagc tcttccaata tcatttctgc gttttctttt aaatccttgt
     1081 ctattccgac ttgaattctg cttttttctt ttggattttt taccttcatt tcgttcacct
     1141 cttttgagta taatatactc attattatat ccattaacta catttatgat tatattatac
     1201 tcttaattag ctactttgca aacaatccaa tcaaatcaag attctacttt actttttata
     1261 cgttctttca tcttctggta tgcaacctct actctttgga catctatatc caatccactt
     1321 acaaccgtac acataccaat ctcatcgcta tccgacactt tatcatattc ttcttcggtg
     1381 atttcaatag gcatataccc atcattaaag catatctcat catctgaata gttttcccat
     1441 tcctcttcat catcttctga ataagtgaca accctatctg ccccctgttc taccatatca
     1501 tcgtaactat cagcaacata ctgcgctttt aatcctttca gttgtaagtc atataaacca
     1561 tacaacctct tactatcttg ttcactgaat aaaattcttt gacgttctaa aattaattct
     1621 ggttcatctt ccacctcttc atctggttct gtaaaatacc attcgataaa ataatatcta
     1681 atatcctcat tcgataaact ttcaaagtcc atattctcct catcaaatcc atcaaaagcg
     1741 ccactacttt gcataccatt caaccaatta atggttctca atcttgcgta ttcacttaat
     1801 accatcttat tctcattcat ggttcttcac cccatattaa ttattttcaa attgacaaat
     1861 caatttattt tgagttaaca aaactaatag ctgttcacta tcaaaaagaa ccttacaaga
     1921 ttctttttct attctctctt ctggcatgta atagccaatc tgttttaaca tcttatctgg
     1981 ataacctttt tgtttggctt ttctcaaaag ctcttcatca ttcccaacat aataataaga
     2041 acaccattgc atacctttac ttttgaattt tgtcatgttg ctaccctctt tcgtttattg
     2101 acccaaccat gaaaaaatat attttgctaa atcttctttt tctatcccat ataaaacatt
     2161 ctctaaatcc aatttatact cttcatcaac aaggctttct gtattgtcat cataaaggac
     2221 atagactgca taatttcttt cgtaaaaggc attagcaaga cttctgctaa tacctaccat
     2281 tcctttccat gtataaccaa aatcaatcaa atcttcatga tctataaaat ccattccttc
     2341 catgctgatt cacactccta ttctgctgtt gtgtaatatg caacgcaatc atctgtccct
     2401 actaaccaca cacaccaatc ttcaatttca tcatcgcttc tcttactcaa ttcctctttg
     2461 gtacaaaaaa ctacttcacc attttctgtt tccatctcat aatcttgtag catgtattca
     2521 aaccaacttc tttcggttgg aaattctatc tcgtggcaac tctggcaaat aaaatcacca
     2581 tattcattga ttcggtagca accttcatct tctacaaatt catgattaca acaaacacat
     2641 ctagtacctg ttaggacttc accctcaatc gttgttctaa cggtatcttc tcttgctacg
     2701 tgttcactgc tgacaagcca atcaatgatt ttctttgcca attcttcatc agaatcggca
     2761 aagcctttaa acgtgtttct ctttccttga aagtagtatt tgcaacttgc ggtagtttct
     2821 atggttccat aacttttttg gaataattca atcatttcac catcaatcac tttttgactt
     2881 ttcgcttcta aattagggaa ctggtctttt cttttttcaa acacttattt cacgctctct
     2941 tcttctaggt ttattccata attttctagc aataatctgt atcccttaat aaaatctttc
     3001 gtagcaaact cttttccgct ttcacaaaac ttgtttagtc ctatctgttg accctcaaaa
     3061 tcaaacaatc gcaatctggt tttatcatct agactaaatc cattttcatc gaacaccatc
     3121 tctaaatgag catagccatc attgttatct gaaaacttca tcacatcttc aatcgtttct
     3181 tgataaggtt catagcgccc accaaaccct gtttcatcat aagcactcac tccagattca
     3241 taggtgacaa aattgataac tcctgtactt ctatcaaaga ttccttttgc taattcttct
     3301 cttgattcat ctcgtaagtc atatgcttta ttgattaaat atattccttg attcaaaacg
     3361 tccatcaaca tgaatcgacc atatccccac tgataatgaa ttgacacgct tactttcgtt
     3421 ttgctgttac catatttgac tgtaattaac gcttgtgttc tttcg
//
LOCUS       DACGLI010000123         3463 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.130, whole genome shotgun sequence.
ACCESSION   DACGLI010000123 DACGLI010000000
VERSION     DACGLI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.130"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            137..748
                     /locus_tag="IXT22_002865"
     CDS             137..748
                     /locus_tag="IXT22_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4864167.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="IXT22_002866"
     CDS             821..1750
                     /locus_tag="IXT22_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAQ4864168.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="IXT22_002867"
     CDS             1908..2645
                     /locus_tag="IXT22_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAQ4864169.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
     gene            complement(2693..>3463)
                     /locus_tag="IXT22_002868"
     CDS             complement(2693..>3463)
                     /locus_tag="IXT22_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864170.1"
                     /translation="MTKSFTEEVTSFKERELHDRYAAIYMDATYIPLKRKTVAKEAIH
                     IAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLFITDGLKGMAGAVQ
                     RFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKKAALEARGAFAEKW
                     KTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIKKYSHRKEQFQNEE
                     SLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE"
BASE COUNT         1149 a          538 c          660 g         1116 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt cat
//
LOCUS       DACGLI010000124         3405 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.131, whole genome shotgun sequence.
ACCESSION   DACGLI010000124 DACGLI010000000
VERSION     DACGLI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.131"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            242..934
                     /locus_tag="IXT22_002869"
     CDS             242..934
                     /locus_tag="IXT22_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4864171.1"
                     /translation="MRKKIIINAGVIIGLMLVIFSGKQYADNILLWGGEDNIEKINNN
                     LTILDTALENKEQKISILNSQLSSNNQTLEQLRTNIEVSKQKVASLENDKNQLVSEKT
                     NLENQLSAKDSELQGKQNEINAKIDEINQKVAEINRLNSDWNNRLQNEKNKFNEEQST
                     INSLNQQINQMLSEKNNIQNQLQATQQKLEEEKSKNSSLNNYIEKLQKAKNDVEDTAN
                     KAQQIVNEHTIQ"
     gene            1362..1754
                     /locus_tag="IXT22_002870"
     CDS             1362..1754
                     /locus_tag="IXT22_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864172.1"
                     /translation="MLDDRLTCSNCGTLFYYEEVRNIVKHRKKEMPIRCPNCNEVIKR
                     KLSHGYFVSYELYEESKINLKKKPKYYKNLKTGAIITEKEFKNLVTEEESRFYNLSGN
                     ICPGFMDQIIENESIESIENYVPVDLPK"
     gene            complement(1927..2109)
                     /locus_tag="IXT22_002871"
                     /pseudo
     CDS             complement(1927..2109)
                     /locus_tag="IXT22_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            2096..2293
                     /locus_tag="IXT22_002872"
     CDS             2096..2293
                     /locus_tag="IXT22_002872"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864173.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(2336..2911)
                     /locus_tag="IXT22_002873"
     CDS             complement(2336..2911)
                     /locus_tag="IXT22_002873"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4864174.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(3066..3405)
                     /locus_tag="IXT22_002874"
                     /pseudo
     CDS             complement(3066..3405)
                     /locus_tag="IXT22_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT         1244 a          503 c          506 g         1152 t
ORIGIN      
        1 gaaacttaca aataaaagct tattcttcag ccaccttcgg gtggttattt tttataaaaa
       61 aatgtaaaaa aatattgata cataaataaa ttagttgtag taaatagttt tagaattgaa
      121 tttctctatc ctttttaaat aattttttag acaaaaaaca gaaagtgtct aaagaaagct
      181 tgacgaagaa aataattttt aataacttat ttaaggaaat tttttgaagg agaagataaa
      241 agtgagaaaa aagattatta ttaatgctgg agtaattata ggattgatgt tagtaatttt
      301 ctccggaaag caatatgctg ataatatttt attatgggga ggggaagata atattgaaaa
      361 gatcaacaac aatttaacta tattagacac agctctagaa aataaagagc aaaaaattag
      421 tattttaaat tcacaattgt cttcaaacaa ccaaactctt gaacaactaa gaactaatat
      481 tgaagtttcc aaacaaaaag tggcatcttt agaaaacgac aagaatcaat tagtatcaga
      541 gaaaactaat ttagaaaatc aattgtcagc aaaagactct gaattgcaag gaaaacaaaa
      601 tgaaattaat gcgaaaatag acgaaattaa ccaaaaagta gctgaaataa atcgattaaa
      661 tagcgattgg aataatcgtt tacaaaatga aaagaacaaa tttaatgaag aacaatctac
      721 tattaatagt ttaaaccagc aaattaatca aatgttgagt gaaaaaaata acattcaaaa
      781 tcaactgcaa gctactcagc aaaagctaga agaagaaaag tcaaaaaata gtagtttgaa
      841 taattacatt gaaaagcttc aaaaagctaa aaatgatgta gaggataccg caaataaagc
      901 acaacaaatt gtaaatgaac atacaatcca atagatatag ttttaattta acaaatggta
      961 tgtttggaga taatgagata gaatataaat gtcataatat tatacaatct aaacaccgtt
     1021 tccttttcta tttttgatga catcagtata tagctactcg aaagagtagt ctttttatta
     1081 ttctcgctta ttattgatat gaaaatttcg atttgacaaa aggtaccgaa taattttgta
     1141 atatgaatta ttatcaagaa gtaattatga tgataacata tggaaactag ttagtaataa
     1201 taacaggtga ttaaactttt gaacgacttg taattctata ttttttcttt taagtaaaaa
     1261 atataggtga ttttttttga cttcatattt ataataaaga cacgtaaatc aattattttt
     1321 cattttactt taactaataa tgtttatttg gagggattat tatgttagat gatagattga
     1381 cgtgttctaa ttgtggtaca ttattttact atgaggaagt tagaaatatt gtaaaacata
     1441 gaaaaaaaga aatgcctata cgttgtccaa attgcaatga agttattaag cgaaagttgt
     1501 ctcatggtta ttttgtcagc tacgaactat atgaagaaag taaaataaat ctgaaaaaaa
     1561 aaccaaaata ctataaaaat ttgaaaactg gagctattat aactgaaaaa gaatttaaaa
     1621 atttagtgac tgaagaagaa agcaggtttt ataatttgtc tggtaatatt tgccctggat
     1681 ttatggatca gattattgaa aatgagtcaa ttgaatcaat tgaaaactat gttcctgttg
     1741 acttaccaaa atagaaaaaa taatcctgtt tttacagtga attattttaa ttttgatttt
     1801 caataaaaat atattacaat aataatcgta atagctaatg aaacaatttc tcaatctttt
     1861 taccactcca aacagggagc gtcaataatt ttgtgtaaat aactcgtcct tctgcaaaat
     1921 aatgggttac tcagtaaaca ttgaagctaa tgtatccgtc acttgttgga agcctttatg
     1981 gcttctattt aagaattttt gattgtatgt atcaaagatg gatactagga aacgctctag
     2041 tgattcttca ttttgaaact gctcttttct gcggctgtat ttcttgattt gtttattgaa
     2101 agattcgatt gtagaaccag aaggaatgga gaacactttt gaactttaca acaaaactac
     2161 tgttgataaa ttaattccaa ttttagttcc aactgattta aatggtcatg atgttttact
     2221 tcgttttaac ggatttttag gtgaggatta tagataccta aaaatttctg atcctcaacc
     2281 tttaacagaa taataaaaaa cgtgtaatca attatttgat tacacgtttt ttatttcaat
     2341 cttcgttgta gtagtggttg cgacataccg aaaggtaatc ttcattacct cctactacaa
     2401 tctgttcacc tgaataaact ggaataccat caacaatacg agcattcatt acagcctttt
     2461 tattgcaaaa atggcaaata gttttaattt cctcaatttt atcagcaaat gtcaataatg
     2521 cttcggatcc cttgaagaga ttattttgaa aatcattctt caatccatag caaattactg
     2581 gtacttcctc attcattacg ataagtgata gatcaataat attctctcta cttaaaaatt
     2641 gagactcatc gaccaaaata caatcaactt ttccgtactg atcaataatc tccactaatt
     2701 ctccgtacac atccatttca gaagtaattg caatagctgg tttcgaaaca cctatacgac
     2761 tctcaacttt tccaaatcct gatcgagtat ctattgcgct tgtcattatg ataactctct
     2821 tcccttgttc ttcataatta tgagccactt tcagtagctc aatactcttt ccactattca
     2881 ttgttccata tctgtaaaat aattgtgcca ttaaatttat tcccttcttt tacaattcaa
     2941 ttattcctta attccatctg cttttatgca gctgctcgtt tattccttga tatgtctata
     3001 acatctacta tccctaaaac caatttataa gccattagag atggtattcc tgaacatctc
     3061 tcatattgtt ttttgagtgg tatatcatct gaaaaactga aggaatcatg aaaatagcga
     3121 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     3181 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     3241 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaatgtgt
     3301 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccattg cggtcgcgcg
     3361 gaatctggag atgaagttcc ccatactcgg tcttgaccgt acggt
//
LOCUS       DACGLI010000125         3052 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.132, whole genome shotgun sequence.
ACCESSION   DACGLI010000125 DACGLI010000000
VERSION     DACGLI010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.132"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            101..571
                     /locus_tag="IXT22_002875"
     CDS             101..571
                     /locus_tag="IXT22_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAQ4864175.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="IXT22_002876"
     CDS             793..1896
                     /locus_tag="IXT22_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4864176.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            2117..>3052
                     /locus_tag="IXT22_002877"
     CDS             2117..>3052
                     /locus_tag="IXT22_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4864177.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTK"
BASE COUNT         1060 a          515 c          654 g          823 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcatac ttcgccgatt gtaaaattaa
     2041 gctagacaac taaaaaaagt catttgtgct acactcaaaa tagttccgac gaaagaatta
     2101 taaggagtga gtacaaatga cctataacca tcttacacca actgaactcg taatgataga
     2161 agcttatttc aatcaatcac aacctgtttc aaaagtagcc aatctgttac aacgttctcg
     2221 acaaactatt tataaggtct atcgttttct taaatctggt ggaagcgcaa tgagctacta
     2281 taaacaatat aagaaaaaca aacgtaactg cggaagacat ccgattgttt tacctgatga
     2341 gcaacaggaa tacattcaaa aaaaggttgt tcaagggtgg gctcctgatg tccttattgg
     2401 tcgagcagag tttcctattg cttgttcggt acgcacactg tatcgaatgt ttaaagataa
     2461 aacctttgac actcacgatt taccaatgaa gggaaaaaga aaaccaaacg gtcataaaga
     2521 aaaaagagga aaacaagggt ttcgccggtc aatccgagac agaaagacag actataccca
     2581 gtttgatcat gaatttggtc acctggaagg tgacactatc gtgggtggaa aacataaaag
     2641 cgcggtcatc acattagttg aacggctatc taaagtcatc attaccttga aacccgaagg
     2701 cagacaggct aaagacattg aaaataggct gaatcaatgg tttcgttgtg tcccaaaaaa
     2761 cttatttaaa tccatcacat ttgattgtgg aaaagaattc tcaaattgga aaaagattag
     2821 taataccaac gatatttcaa tttattttgc ggatccagga acaccttctc aacgaggatt
     2881 gaatgaacat tcaaatggct tattacgtaa agatggtttg tataaagcta tggattttaa
     2941 tggtgtatct gaaaccttta tccaatcggt ggcatcgaaa cgaaatcata ttcctagaaa
     3001 atcattacac tatcggacac caatggaagt atttttgagt tacgtcacaa aa
//
LOCUS       DACGLI010000126         3022 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.133, whole genome shotgun sequence.
ACCESSION   DACGLI010000126 DACGLI010000000
VERSION     DACGLI010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.133"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(287..649)
                     /locus_tag="IXT22_002878"
     CDS             complement(287..649)
                     /locus_tag="IXT22_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864178.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="IXT22_002879"
     CDS             complement(723..1103)
                     /locus_tag="IXT22_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAQ4864179.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="IXT22_002880"
     CDS             1185..2360
                     /locus_tag="IXT22_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4864180.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2436..3020)
                     /locus_tag="IXT22_002881"
     CDS             complement(2436..3020)
                     /locus_tag="IXT22_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4864181.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          942 a          577 c          498 g         1005 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atatttattc aaaataaaag gacgagacct tactaggttt
     2401 cgtccttttt cataattact ccgtaccata ccaaactatt ctgaaatttc aattgtttca
     2461 atcactacat catgtacagg tcggtcttgt ggaccacgtt gtacatttgc gatttcatct
     2521 actgtgtcca tcccttctag tacatgtcca aagactgtat gtcggaaatc tagccaagga
     2581 gttccgccac ctttatacgc ttcaatgatt tctgatggga atccagcacc ttctagttgt
     2641 ccaagcatat tagctggcac atttgtgtta tttacaataa agaattggct tccgtttgtg
     2701 tttggacctg aatttgccat agataaagct ccgcgaaggt tgaacagttc acgactgaat
     2761 tcatcttcaa aactttcgcc ataaatactt tcgccaccca ttcctgttcc agttggatcg
     2821 ccgccttgga tcatgaaatc aggaataacg cggtgaaaaa tcacgccatc ataataacct
     2881 tttttggaaa gttcaatgaa attttgaacc gtcttcggtg ctagttcagg gaataattga
     2941 acagtaatgt caccacggtt tgttttgata acagcttttg gtcctttttc actttttaaa
     3001 tctagttgtg ggaatgccat at
//
LOCUS       DACGLI010000127         3020 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.134, whole genome shotgun sequence.
ACCESSION   DACGLI010000127 DACGLI010000000
VERSION     DACGLI010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.134"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            384..800
                     /locus_tag="IXT22_002882"
     CDS             384..800
                     /locus_tag="IXT22_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAQ4864182.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            814..1380
                     /locus_tag="IXT22_002883"
     CDS             814..1380
                     /locus_tag="IXT22_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAQ4864183.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            1403..2389
                     /locus_tag="IXT22_002884"
     CDS             1403..2389
                     /locus_tag="IXT22_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4864184.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(2544..>3020)
                     /gene="scm"
                     /locus_tag="IXT22_002885"
     CDS             complement(2544..>3020)
                     /gene="scm"
                     /locus_tag="IXT22_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4864185.1"
                     /translation="STDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDSST
                     TTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNR
                     TNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT          910 a          566 c          632 g          912 t
ORIGIN      
        1 ttatgtaaaa ttaaaggaat aagatgcccg agataagcct ccatgagcaa gacacaggtg
       61 tcacaacctc tgttacaacc tcttgttata aacggtgttc cagaagtagc ttcttcgaaa
      121 aataagccga aatttcacaa aaacttgaaa agtaattttc gtaaattcct tcttatttct
      181 tgaagttgcc cacttctgtc acaacctctt gttataaacg gtgttccacc tgctgcttct
      241 cggtaataag cccaaagaat tagaaaacat ggaaagctgt tttctattct tcgttcttat
      301 tactcaaagc aagacacagg tgtcacaacc tcttgttttt atgctaaaat tgggtgagtt
      361 aatctggaaa aaggagaaca aaaatgagcc ttaaagaatt tgctgaaaaa agtctgctca
      421 aaccttggga tgtttttatt attttgcttt tgactgttct ttctttttta ccagtcatga
      481 tttttggtct tcagcaaaac accgcaacag cagaaaaaga agcggtactg cgtgtggatg
      541 gcacagaaat caaaacattc cctttgatgg ctggagaaga gagcaacaca tatacttaca
      601 aagatgaaca cggagattat aacttgatcg agatagatgg cgatcgagta cggataaaag
      661 aagcagattg cgatgaccag atctgcgtac gtcgaggctg ggcaacgaaa aatggcgaaa
      721 ccatcgtctg tttgccacat aaattagtga tcgaagtccg ttcaacagat ggaggtgacg
      781 aagacagtct gatttattag accttcacac accatgagta aattacaaaa aatgatttat
      841 atttcgctac ttgttgcaca aggagtgatc attggtttat tggaaaatat gatcccttat
      901 cctttttctt ttgcgcctgg tgcaaaacta ggcttagcca atctaatcac gatcgttgcc
      961 atttttacca tgaaaaaacg agacagcttc ttactacttt ggctacgact attcctgact
     1021 actttgctag gcggaacgat ttccacattc ctttatagta tgagtggtgc tttgcttagt
     1081 tattttggaa tgttattggt caagcaatta ggaccaaaac gtgtcagtat catcggaatt
     1141 agtgcggccg gcggtttcat gcataatgtc ggacagcttt tgatggcttc tttcattgca
     1201 caatcatgga cagtcatgtt gtacttgcca gtcctttcag ttttagggat tttatcaggg
     1261 attgcaatcg ggatcgcagc gaattatctt ttacgacatg tgcagacact tcaacgattc
     1321 caaaaagatt atgagcaggg aaccaaacaa aaatggagcc caatgtttac caaaaaataa
     1381 tcgtcacaca aggagttttt ttatgaagct acatccaatg tgggaaaact atcctgcttt
     1441 aagtaaagaa ttgacagaaa cactaaaacg gatggaagaa actgtccgcc tgaaaaacaa
     1501 acctgtcgaa caagcaatca aagaaacgat ccatgccggc ggaaagctgt tgcgtcctgc
     1561 ctatcagcta ttgttctcac aatttggacc agagcaagat cgagacaaag ccatcgcttt
     1621 ggcagcttct atcgaaatgc tccatacggc cacactgatc catgatgata tcgttgatga
     1681 agcggatctg cgacgtggtc agcctaatat ccgtagtcag tttggtaatg tcgtttctgt
     1741 ctatgcagga gactatttat ttgtctgctg ttttaaacta ttgtctgatt actccacttc
     1801 cttgaaaagt ctccaattga attctcgcag tatggaaaaa gtattgaatg gcgaattagg
     1861 tcagatggat gatcgctata attatgaact ttctgtaaaa gaatatttgg aaaatatttc
     1921 aggtaagaca gctgaactgt tccaattaag ttgttctgtt ggcgcttttg aaagtggaac
     1981 aagcgagcgc ttcgcaaaaa aagcaggaga tatcggactt tctatcggga tggcctttca
     2041 gattatcgat gatattttag attatacaaa agagagccag gaaatcggca aacctgtact
     2101 agaagacatg cgtcaagggg tctattcttt accgttgatc tactctttgc aaaaaaacaa
     2161 accaaagcta ctaccttatt tagagaagaa agcggcaatg acagaagaag atgtcgacgc
     2221 cgtacgcaaa atcgttgaac atacaggagg cgtggaagaa gctaggaagt tagcggcctc
     2281 ttacacagaa aaggctttga aggaaataaa gaaattacct gccacctctc ttcgaacaaa
     2341 agagaatctc ttttccctta cccaactgat tttggatcgc aaagactgaa tagggaaagg
     2401 ttcgatacgt aaataaattt ctcagaagga aatctacgtg ttttttgaca aattgaattg
     2461 tagttcttgt atttatgata aaaagcaaaa ataaagagca acgtccgtta gcgacgttgc
     2521 tcttttttat cttgaatatt tttttacctt ttcgatttct tataactcat aaaagtgatt
     2581 cttaaaccga ttacaagtaa tataacgcct gcgagtgtta tccaattatt cgattgactt
     2641 ccagttttag gaagtgctct ttttgatttg tttccattgt cattgcttgt tttattagtt
     2701 aagttaaagt tcgtcctgtt atccgaactt gtttttgaga aggagacact tgcatgacgt
     2761 gtatcgcttg tggtagacga cgtgtctgta ctatcgcttg aagttgatga atctgagcta
     2821 tcacttgtgg tagaggatgt atctgtactg tcacttgaag ctgacgtgtc cgtgctatca
     2881 cttgtagtgg tagatgaatc tgagctatca cttgtggtag aggtagtatc tgtactgtca
     2941 cttgaagctg acgtgtccgt gctatcactt gttgtggtag atgtatccgt actgtcgctt
     3001 gaagctgacg tgtccgtgct
//
LOCUS       DACGLI010000128         3011 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.135, whole genome shotgun sequence.
ACCESSION   DACGLI010000128 DACGLI010000000
VERSION     DACGLI010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.135"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            177..359
                     /locus_tag="IXT22_002886"
     CDS             177..359
                     /locus_tag="IXT22_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAQ4864186.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            462..746
                     /locus_tag="IXT22_002887"
     CDS             462..746
                     /locus_tag="IXT22_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864187.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            762..998
                     /locus_tag="IXT22_002888"
     CDS             762..998
                     /locus_tag="IXT22_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864188.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            1020..1274
                     /locus_tag="IXT22_002889"
     CDS             1020..1274
                     /locus_tag="IXT22_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864189.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
     gene            1356..1541
                     /locus_tag="IXT22_002890"
     CDS             1356..1541
                     /locus_tag="IXT22_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAQ4864190.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            1608..2003
                     /locus_tag="IXT22_002891"
     CDS             1608..2003
                     /locus_tag="IXT22_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAQ4864191.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            1993..2370
                     /locus_tag="IXT22_002892"
     CDS             1993..2370
                     /locus_tag="IXT22_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864192.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            2371..2766
                     /locus_tag="IXT22_002893"
     CDS             2371..2766
                     /locus_tag="IXT22_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864193.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
BASE COUNT         1059 a          507 c          523 g          922 t
ORIGIN      
        1 tttatgttta tgtatatgta tatgaatata aacgtattag gtacgaacac ttttaaattc
       61 ttttctgggc tttgttttta gggtagggct aaaaaaaaca tcaccatctg atccaaaaca
      121 gctcagaaac gcatttaaac gtatctgata ccaatattac agaaggagtg tatcgtatga
      181 ttaacctatt tcttttagtg acagctagta cattattctt tactggaata tcactgataa
      241 tttcctattt gatctataag aaagccgaaa atcacacaag caaagcaatc ggactagccg
      301 tttcatcctt tttaactttg ctgactttat ttgttacttt atcgttttct tttgtttaga
      361 acagctgatc cattagcacc tttttctctt tacattatac acactgttgt gtataatgta
      421 tttgtaaaca agctaattaa cttttaggaa ggagtgacaa gatgctaaca gctactttac
      481 agcaacctac tcacgttgct attgcagaaa gttatacaat taatgcaggg atcgttaaac
      541 agctgatcaa ggatcgagaa ttcaaaaagt ttaacagtcg gcaagcgtat aacagacagc
      601 taaagaaagc tattctaaag cacaaagatt ccttcatcgg gaacttggaa agtgtagatg
      661 ttaaaactgt ttcaacggca ttttcagttg ttgaagtgac tattgacggt cgcttgattt
      721 ctctatttgc ttttggaatt aattgatagg gagtgtgaac tttggaaggt aagacttttg
      781 cagaaatttg gactgaattt attgaggtac caactcgcat tgatccgata acttctgaaa
      841 aggtattgga tgcagacttc tacaatctca aagcaggtac tagccttgaa tgcgtttgga
      901 tgtatttaga agagcatttc aaaggcgtaa cgctcggtca cgtcttatac cacaatggtg
      961 ccgagtggga tgcaattgga aatatccatt tttcttaata taagaaagga gaacacaata
     1021 tgaattatac cgatgaagaa caaatcgctt tggaatacgt tttcacaaat gaagaagggg
     1081 aggaaattga aaaagtcttg atcatttcat caaaagactt ggagaaggct ttggcttatg
     1141 aaccatacga atcaaccgta actgtcattg aattcttaga tacctatact tctaatgata
     1201 cttgggaaat tatgaatatt tgcaacgcta ataacattca atttgctgaa aaaaccaata
     1261 aatcatttta ttagttttgc aataaaacat cctctttttc tattgattcc atacacaaca
     1321 atgtgtataa tagattttgt aaagggaggg tagctatgcc taagacagca agagaaattg
     1381 taaaaattct caaatctaac ggcttcaaaa agactggaca aactggcagt catgcaaaat
     1441 tttataattc caagactaaa agaacggtcg ttgttccgat ccacaatggt gatgtaccac
     1501 taggaacaga agctaatatc tggaagcaag cagggcttta acagccttgc cttcctattt
     1561 ggtattaggc atactatcct ctcttacact agaaaaggag cgaggaaatg aagacaaaaa
     1621 atatttttta tccggcaatc ttcgagaaag aaggagaagc ttataacatc gttttccctg
     1681 acttaccgga aatatctacc tttggaaata gtcttgaaga agcatattta aacgctaagg
     1741 atgctttagg attagcgcta tatagtgtac cagatgcaga atttcctaaa ccatcagcag
     1801 tggaagaatt aactttgaaa gccaaccaag tggtagtaat catccaacta aacattaaac
     1861 ttttccgaag aagcttaaat acaaaaacaa ttagaaaaaa tgttagtgtt ccggaatggt
     1921 tagttctttt agggaaggag aaaaacataa acttctctca actacttcaa aaagcactag
     1981 aagaagagtt gcttgaaaag taaaaaggag accgaaccta tgaaagctac acacttaaac
     2041 tatttctctc gaacgttaat caataatcta ttaaaagata caactggcat tagcgttagt
     2101 accaaacact ttgccaatga tctaattatt tttgaggata ataacttgcg aattgagatg
     2161 tttattgaac aggcaacccc taactcaata cctgaattct gctatacgca cactgaaaaa
     2221 atgaaacatg caaaatcagt taaagatgtt gaagcattaa gtgaatcact aacgaacgct
     2281 ttaaacctcg ttaagaaggc aaaattgtta tttgaatttc aaaccgacta ccacaatgag
     2341 ttgcttgctc aatctgaaat tttagattaa ttgaaacagg agaagagaaa gatgaaacaa
     2401 acacaaacag aaaccgttaa cgatacgctt gctgatcaat tagcaggtta ttataaatta
     2461 tttgagatgg gtaaagcaca gcgcttgatc cactatcttt ggaaatacaa aattttgttt
     2521 cttttttggg aatcaacact aacattctca gttctttttt ataagtcaga tttttataat
     2581 caacacttag ttttagggag ttttttgctt atctacacca ttttgatgct taatttatat
     2641 acctacatca cacttgaaga acacttagta attagcgatg cagggatcga gagaaacatc
     2701 aaaagggtat ccttcaagat cacgttaaac aagcctaccg ataaaaagct ctcagaagcg
     2761 ttctgagagc ttttgacatt ttcttgtata attttatcct aacacattac aaagcaccta
     2821 attcgagctt atatcaagca aatttgctat ttattactca atacatatct aaaaattact
     2881 tgatggaaaa ttagatacat ggtaagcatg aaaagaaaat caatttgagc agatgcagta
     2941 caatacatag caatttaaaa gctctcagaa ggcttctgag agcttttaat atattctttg
     3001 ataatttgtc t
//
LOCUS       DACGLI010000129         2967 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.137, whole genome shotgun sequence.
ACCESSION   DACGLI010000129 DACGLI010000000
VERSION     DACGLI010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.137"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(84..1031)
                     /locus_tag="IXT22_002894"
     CDS             complement(84..1031)
                     /locus_tag="IXT22_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4864194.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            1277..1741
                     /locus_tag="IXT22_002895"
     CDS             1277..1741
                     /locus_tag="IXT22_002895"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAQ4864195.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(1803..2846)
                     /locus_tag="IXT22_002896"
     CDS             complement(1803..2846)
                     /locus_tag="IXT22_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAQ4864196.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLFYGLAVGLLQ
                     TVMALLFIWLIKV"
BASE COUNT          981 a          587 c          565 g          834 t
ORIGIN      
        1 tttattcgga aaaaaggact gtgacaagac ttttgtcaca gtcctttttc atttaaaaaa
       61 atgtttactt catttgacgt atattattgg tgaggcttca attcatttgg cttcactttt
      121 tctgtttctc ttatgatata aacaggacgc tgtttcgttt ctaagaagat tttcccgata
      181 tatttcccga tgattccaag acataacaat tggattccac caatgaacag gaagatcgag
      241 accatggaag gccatcctga tgtaggatca ccaaacaaca atgcccgcaa aataatgaac
      301 aaaattgcaa taccagaacc gacacaagac aaagcgccga taaatgaagc aatcgttaac
      361 ggtgcatccg agaagttcac gataccatca atcgagtagt tgaataattt ccagaaggac
      421 caagatgttt cgccagccac acgttcgcgg ttttcataag aaatatattc tgttttaaac
      481 ccgacccagc taaataatcc ttttgaaaat cggttgtatt ctgttaattc taggacggca
      541 tccaccattt gacgagtcat caagcggaaa tcacgagcgc catcgaccat ttctgtatcg
      601 ctgattttat tgatcaactg gtagaatttt ttcgcaaaga aactgcgtat cgcaggctcg
      661 ccttcacgag tcgaacgccg ggtgccgaca caatcgatat cagaagtagt gatccggttg
      721 atcatctcag gaagcaattc gggcggatct tgcagatcaa catccatcac ggtcactaaa
      781 tctcctgtag aagcttgcaa tccagcgtat agagccgctt ctttcccaaa atttctggaa
      841 aatgagacaa agcggacata aggataagct gaggctagct tcttgattgc tgctaacgta
      901 ccgtcttttg atccgtcgtc aataaacaaa tattcgaact catgggcacc tttgaatttt
      961 tcaacctcat caaaaaaaag aggaacagtt ttttcttcat taaaacatgg gacaacaatt
     1021 gatactttca tcgtttctat cctttcaatc gtatgtttat atatggttta cattcaaaat
     1081 ttaataaacc ttaaataaca cctttaaaat ttgattttac gtaaaagaac aggtattctt
     1141 tttgtaaact aacgtattta gtttaccatg tttcctcggt ttatcaaact tttaagaaca
     1201 atttttatta gttggcaagt agttttggat agagaaaaag gaggaagttc cagtctattg
     1261 actagaagca aacaaaatga aaatacacac acctatcggc tttttatggt tagatgcaga
     1321 tgaatccgga ttgactgctg tatcttttca gccaatttca gaaagcgaat cagcgaatca
     1381 gcaaatttta acgcgcacac aagaacagtt tgaagaatat tttgcgggaa aaagaaaaga
     1441 atttgatgtt cctttatcta taaagagagg tacgcctttt cagcaaaatg tctggaaagc
     1501 tttgtcgacc attccttatg gagaaatccg aacgtataaa gaagtagccg ttgctgttga
     1561 tagtccgaaa gctgtgcgag cgattgggca ggcaaatcga accaatccat tgccaatcgt
     1621 tattccttgt catcgagtga tcgggcaaaa tggaaaactg acaggatata tgggaaacgc
     1681 aatagatggg gttgaaatca aacgccaatt gttgttgtta gaaggatatc tgcaaaatta
     1741 aaaacagttg tgattcggac attgttccat gcgagaatca caactgtttt ttcatgttca
     1801 ttctaaactt tgatcagcca aataaatagt aaagccatca ctgtttggag aagcccgaca
     1861 gctaatccat aaaataagaa gcgtgtacct tctttcatga attttgcaaa gtctaaacgc
     1921 agaccaattg ccgctaaagc agtgatctca aaccagctgc tgataaaatg tgccgattgg
     1981 tcaataacta caggtaaaga aaacaagctg ttgaccaaac aaaagatcac aaaccctaat
     2041 acataccaag gaagtggtaa ttttcgtttt ttctgcgtat cagttggcgt ttcaaacaga
     2101 gctggttgtt tcttgtgcat gaatttttca aacagataga caacaacaac gagcatcata
     2161 atacgtagaa tcttaaatag catggcgaat tcgacaacag aattgtcaag taagcttgcc
     2221 ccagcgacta cttgaccaac agattggagt gtgccaccca aaagtgcact tttttcaatg
     2281 agatttccac caaacaactg taatccaaga aaagggagag tcaacatcat cacagtaccc
     2341 agtagattga ctagtgtgat gatctgtcct ttttcttcct ctttcgcatg gatggaaggg
     2401 gcgatcgaag caatagcaga agaaccacaa acagcgtttc ctccagccat catcaaagaa
     2461 gaagtatcgc tgaattgcag ttttttacca atcaagtaag caccgatgat agtgactgac
     2521 atttgcagta acacaaaaac aattcctttt ataccaattt gagcaatcgt ttgagctgtg
     2581 acagttgcac ctagtaaaaa aacagagaat tctaatagtt tgctttcagc aaattttgtg
     2641 ccgattgcta gaacaggctg tttaaaaaaa gtatttccta ataaaatacc caataaaata
     2701 gcaatagtcg ctccacctaa ctgtggcaga taaatagcaa gaagcctgct gaaggcagcg
     2761 atggcaaaag aaagcagtaa accgggtaag atttcgcgga ccgctgaatc ctttacagat
     2821 tttattggat gtgacaatga tttcatttga tcggttcctt tcgtcaataa atactaaaag
     2881 catactcgaa catagtagca ctaaaccagt attttgacaa aagaacaaga ggtcgtgaca
     2941 aaagtcttgt cacgacctct tgtttcg
//
LOCUS       DACGLI010000130         2870 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.139, whole genome shotgun sequence.
ACCESSION   DACGLI010000130 DACGLI010000000
VERSION     DACGLI010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.139"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            256..1224
                     /locus_tag="IXT22_002897"
     CDS             256..1224
                     /locus_tag="IXT22_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4864197.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1217..2248
                     /gene="vanA"
                     /locus_tag="IXT22_002898"
     CDS             1217..2248
                     /gene="vanA"
                     /locus_tag="IXT22_002898"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4864198.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2254..2862
                     /locus_tag="IXT22_002899"
     CDS             2254..2862
                     /locus_tag="IXT22_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4864199.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          847 a          549 c          702 g          772 t
ORIGIN      
        1 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataatttttt
       61 aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa
      121 acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag
      181 agaaagattt gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa
      241 gggttggtct taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag
      301 gcagatgcat tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc
      361 aacgtgtcgg aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat
      421 aaatcagaga tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt
      481 tctacccgaa gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc
      541 actgtcgaca atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt
      601 cttatggcag tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg
      661 ttggacagcg accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc
      721 cagataggca aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat
      781 agtcgcagcc gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc
      841 gatatcgtta cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa
      901 caaatacaga gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta
      961 gatacctatg agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat
     1021 gtattggaag gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat
     1081 caatttttac ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat
     1141 tataccgagc aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt
     1201 gaaaggagac aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga
     1261 ggagcatgac gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa
     1321 atacgagccg ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc
     1381 ttgcgcggaa tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat
     1441 gcacggatta cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt
     1501 ttcagctttg catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc
     1561 cggtatccct tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt
     1621 gacatacatc gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa
     1681 agatgatagg ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc
     1741 aggctcatcc ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga
     1801 atcggcaaga caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt
     1861 cggttgtgcg gtattgggaa acagtgccgc gttagttgtt ggcgaggtgg accaaatcag
     1921 gctgcagtac ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa
     1981 cgcagttata accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac
     2041 ggcaaaaaaa atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt
     2101 acaagataac ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata
     2161 cagtcgttat ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg
     2221 cttgatcgta ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat
     2281 gaaatagtac acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga
     2341 aaaccggttg acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg
     2401 cttttgaagg caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt
     2461 taccgtccta agcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac
     2521 ctgacaaagg aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac
     2581 gtggcttcaa aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta
     2641 gacacgggtg agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat
     2701 catgcggcaa atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc
     2761 atggaaaaca gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac
     2821 gaaccatacc ccaatagcta ttttgatttc cccgttaaat aaacttttaa
//
LOCUS       DACGLI010000131         2719 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.140, whole genome shotgun sequence.
ACCESSION   DACGLI010000131 DACGLI010000000
VERSION     DACGLI010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.140"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="IXT22_002900"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="IXT22_002900"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4864200.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1065 a          420 c          556 g          678 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt
     2701 tgagatattt ataatatca
//
LOCUS       DACGLI010000132         2702 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.141, whole genome shotgun sequence.
ACCESSION   DACGLI010000132 DACGLI010000000
VERSION     DACGLI010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.141"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..1261
                     /locus_tag="IXT22_002901"
     CDS             <1..1261
                     /locus_tag="IXT22_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4864201.1"
                     /translation="GVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGG
                     TVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVE
                     VTDNRSNADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNK
                     KGTIVVTYPDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKED
                     LPKGTTYTWKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPIT
                     EGDQIVTGKTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESG
                     NTSEPTNVVVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSN
                     IFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1395..>2702
                     /locus_tag="IXT22_002902"
     CDS             1395..>2702
                     /locus_tag="IXT22_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4864202.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT         1060 a          360 c          525 g          757 t
ORIGIN      
        1 aggtgtcatt gaagtaacgt atccagacgg tacgaaagat acggtgaaag ttccagtaga
       61 agtgacagac aatcgttctg acgccgataa atatgaacca acagtagaag gcgaaaaagt
      121 agaaattgga ggcacagtag atttaacaga taatgttact aacttgccag cgttaccaga
      181 aggaacaaca gtaacagatg ttactcccgg cggtacaatt gataccaaca caccaggcaa
      241 ttatgaaggt gtcattgaag taacgtatcc agacggtacg aaagatacgg tgaaagttcc
      301 agtagaagtg acagacaatc gttctaatgc agataaatac aatcctgaag gacaaaaagt
      361 gactacagac ttaaataaag agccagatgc atctgaggga attaagaaca aagaagattt
      421 accaaaagga actacttatg cttggaaaga gaaagtagat gttagcacag ctggaaataa
      481 aaaaggtact attgtagtga catatccaga tggatcatct gatgaagttg aagtagacgt
      541 tacagtgaca gatactcgtt ccgatgcaga taaatataat cctgaaggac aaaaagtgac
      601 tacagactta aataaagagc cagatgcatc tgagggaatt aagaacaaag aagatctacc
      661 aaaaggaact acttatactt ggaaagaaaa agtagatgtt agtacagctg gaaacaaaaa
      721 aggtactgta gtagtaacat atccagatgg atctaaagaa gaagtagaag ttactatttc
      781 tgtagtagat aaaaaagcac cgaataaacc tcaagttgat cctattacag agggtgacca
      841 aattgttact ggtaaaactg aaccaaatgc agaggtgaca gttacattac cagacggaag
      901 tcaacaccat gggacagctg ataaaaatgg taattttaca gttaaagttc ctaaattaga
      961 ggcagggaca aaagtgatag taactgcaac tgatgaatct ggtaatacta gtgaacctac
     1021 taatgtagtt gtttcttcca acaaaaaaga cagtggaaaa aacggtagta aaggtagtaa
     1081 gactgacaat caaggtagca acagcaatca agacaaaaat agaggcaaaa gccagtcctc
     1141 aaaagttttt cctaagacgg gagagagtga cagtaatatc tttactatta gcggtggttt
     1201 aatactgtta ggaacgttag gattattagg gtataaaaat cgaaaaaaag agaatgaata
     1261 gaaaatcaat ttcttaagtc ttctctgaga agaggaagaa tctttttctt cctctttttg
     1321 cttttttatg atgggaaata agtgttagtt aaagatgaat atacttttta tagaaaggaa
     1381 aagaatgtaa ttaagtggaa aaaatagtaa ttattggttc aaaccattca gggctagccg
     1441 cagctcgatt tctaaactta agcgattcaa attatgaagt tattctaatc gataaaaaat
     1501 cagaaattag ttacttggaa tgtgggacat cgttatttat aaaaggagaa gtaagtaatt
     1561 tagaagatct tttttatcaa aatagaatga cactaaattc tgagataaaa aagttatttc
     1621 tagagacaga agttgacaaa attgatattc aaaataaaaa gattagttgt gtaaaaaaag
     1681 atggtacaag attctctcaa gaatatgaca aagttatatt agctacaggt tcaaagcaaa
     1741 ttatgctaga tataccgggg aataatttag ctaatatttt ttcgataaag aattttccaa
     1801 atgcaaaaga gatttttaaa gctttggatg atagtactat taaaaaagta ggaattattg
     1861 gagcaggata tattggagtt gaaattgctg aagccataag aaaaagaggg aaagaagtat
     1921 atcttttcga tgttgcagat agagtgttgt cgacttatta cgaccgtagt ttttcagata
     1981 aagttgaaga aatactatca aaaaatggaa tacatctttg tctatcagaa agtcctaaaa
     2041 aatatttagg aagaaaaaag attgaaaaaa tagtcactac aagtggtacc caatactcta
     2101 tggatatggt cgtacaagct ataggatttc tatctaatag tccaattggg gaaaaggaac
     2161 tcttgagaga tgttagtgga gcatatctaa ctaatgaata ccagcaaaca aatataaaag
     2221 atatatatgc tattggggat tgtgctacaa ctttttttac gtccattaat agaagtagtg
     2281 ttgatttttc tatttctaat gctctaagaa cagcttatat tgcaactcaa catattaaca
     2341 atcaagattt tacaccttct ggttcccaat ttacaaatgg cttttctata tttaattaca
     2401 atttttacgc agcaggtttg aatttaaaaa cagcacgatt attaagtgag tctatagatt
     2461 atatagaaat agaagatttc attagacctg cttttttgag aaaaaatagt cgtgtaaaat
     2521 taagaattag ctttgaaaaa aatacaaaga gaatagtagg tgtacaactt tgtagtcaag
     2581 aagatttatc tggactatta tcaatgtttt ctcttgctat agaagaacaa attacattag
     2641 acaaattgaa aatgttagat tatttatttc atcctagttt tagccaaccc tataatttta
     2701 tt
//
LOCUS       DACGLI010000133         2484 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.142, whole genome shotgun sequence.
ACCESSION   DACGLI010000133 DACGLI010000000
VERSION     DACGLI010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.142"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(1014..1304)
                     /locus_tag="IXT22_002903"
     CDS             complement(1014..1304)
                     /locus_tag="IXT22_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864203.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2204)
                     /locus_tag="IXT22_002904"
     CDS             complement(1512..2204)
                     /locus_tag="IXT22_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4864204.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          458 c          349 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgcaa cgacaatccc accagtaata aatttctttt tcatttgcat agctccttaa
     2221 tccaatactt ttacatgcta aaagtaagtg atctcaaaca caatgtcaag cgtttttaaa
     2281 ttacatatgt aattttaata taaatactat caaatactca tttaatcctc cttttttatc
     2341 tatttaaaaa atctttttta tagagaaaaa tgcaggttaa tactttctta aataaatatt
     2401 tatggtgaac aaaaacaaaa aagcaagttt tattaaacgt aacccttttc atttcataga
     2461 ttactgtatt tattacaaaa aacg
//
LOCUS       DACGLI010000134         2454 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.143, whole genome shotgun sequence.
ACCESSION   DACGLI010000134 DACGLI010000000
VERSION     DACGLI010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.143"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            132..344
                     /locus_tag="IXT22_002905"
     CDS             132..344
                     /locus_tag="IXT22_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864205.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAA
                     AVVITAVAKASDSILAWLKFKKEQKK"
     gene            506..1024
                     /locus_tag="IXT22_002906"
     CDS             506..1024
                     /locus_tag="IXT22_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HAQ4864206.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEF
                     KLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGN
                     LSYEMISKVLSL"
     gene            1031..1543
                     /locus_tag="IXT22_002907"
     CDS             1031..1543
                     /locus_tag="IXT22_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864207.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
     gene            1814..2437
                     /locus_tag="IXT22_002908"
     CDS             1814..2437
                     /locus_tag="IXT22_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864208.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          944 a          310 c          408 g          792 t
ORIGIN      
        1 aaaacactat atattccgaa aagtgagtat ctccattcat aaaataatca acatatttaa
       61 aaaatctaat tagctttttt agtcaatcta aagttcttta ttctatgata taatgttact
      121 gtagaaagtt tgtggcggtt tggcaaatcc aattgaagga gcgtggtgcc tatgggctta
      181 ttagcttatc ggacgtactc tgtagaaagg aaatgcctga tttgttctca ttggatcaaa
      241 tcattgctat tatcggagca gcagcagtag ttattactgc cgtagcgaaa gctagcgatt
      301 cgattttagc ttggttaaag ttcaaaaaag aacaaaaaaa atagagccgt ctcaactttt
      361 ggcgaggtag acgagctcta aagctttatt tacatgccat ccgctttgaa cggactacac
      421 tgggcatgtg acagcatgcc ctttcattta tattatatct cattctttta tataatgaaa
      481 gtaaataaat catggaggat aaaatatgga taaatttaat agattaacat taataaatca
      541 gtttgaaatt ttaaaagctt taaatcctaa cgaagaaaaa tactatgctg aaaaaataga
      601 aatactaaca gaaggttacg aatatcacta tagtgaaata tttgaaaata tttctgatcc
      661 attgccagaa gaagattcgc ggtttgttct agacatatta aatatgtata gagatattac
      721 ttttagtaaa aataaattaa aagatataaa ttcaattgat aattattata tacaatttaa
      781 aggttttgac tttaatagct ctaccgaatt taagttagca ctttatgcac aattttttat
      841 tgaaaaatta aataggtttc aagaaatagt tgaagatagt gattttaaca cttttaatag
      901 ccataaaccg atgagaggta cttatataaa atttctcgaa aattataatg atttaaaatc
      961 taccaataat tatcaatttg gaaacttgtc ttatgagatg ataagtaaag ttctaagttt
     1021 gtgatgataa atgaaattaa atagtataaa tgatttattt gctattatag gtgttattgc
     1081 taacatactt ttttcgtgtt tgaattttag atttactcaa aagaacaaaa agaacaaact
     1141 cagtatagaa caaatgaaaa aagacattga aactgattta aaaaatgacc ataaagaaag
     1201 aagaaaaatt gaagaatata cttctttaat ggaaaagtgt aaagcaactg atgcaatttt
     1261 tagcttttta agaaaaagtg atgagataat cacacgtgaa aatatagatt tagaaaatga
     1321 gattagtaaa cttgaatcta tcttttccga tataaattct cttaagtatt taatcgtcga
     1381 agaaaattcg gatagctttt tagaatttga aaaatatcta acagatctta tagataatag
     1441 aaataatgaa ttaatgagac aaaacattgc aagattcctt actaaattag tttctgaatg
     1501 gaaaagtatt atttctcaaa atatggataa attaagatat taaggatgtt agttttaaaa
     1561 taaactaatg tccttatttt tgtgttcaca tttctgttac ctaagaaata cttaaaggag
     1621 gtgatgtagc cagcaacgac tacaacttga acccgctatc tacagtttat ttgttgtttc
     1681 ttttgggtat actctaatgg tacaaatcca tatttgctta aagcgttgat ttttcagcgg
     1741 tttttcttta ttgcaaagtg taccctaaga cctgtatact aatagtaaat agattggata
     1801 ggaatgatgg caaatgtatt tagcttattt aagagtttct tccgacgatc aaagtttagc
     1861 tcggcaacat aagctaattg aaaattggtc agtcaaaaat aatattgctg aagacgattt
     1921 aaaaattttc gaggaaaaag tctctggaaa aaatattgaa aacagaccag agctgcaaga
     1981 gcttatttct ttcatacgtg aacgagatac gattattatt cctagtcttg atcgattagc
     2041 aagaaatagt aaagatacaa aagacttact tcaattgttt cgtagtaaag gtgcttctat
     2101 tgaaatatta gacctaccgt cgtttaatgg ggtaactgac cctgcattaa gagacttgct
     2161 aacaaattta gtcatagaag tgtttagcta tgttgctgaa aacgaacgga aaaaaatcaa
     2221 agagcgtcaa aaacaaggca ttgaaattgc aaagaaaaat ggtcgttata ctggtaaaaa
     2281 gattcaatac catgccaatg caacaggaaa aaacaaattg atttacgatg aaattgttga
     2341 tggtctgaag aaaaaagaaa ctatttctaa aatagcaaag aacgcaggag ttacaagaaa
     2401 aaccgtttat cgagtaaaaa gagatttagg aatgtaatat gttccagtta gaaa
//
LOCUS       DACGLI010000135         2406 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.144, whole genome shotgun sequence.
ACCESSION   DACGLI010000135 DACGLI010000000
VERSION     DACGLI010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.144"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            80..>2406
                     /gene="esp"
                     /locus_tag="IXT22_002909"
     CDS             80..>2406
                     /gene="esp"
                     /locus_tag="IXT22_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAQ4864209.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT          871 a          377 c          488 g          670 t
ORIGIN      
        1 ctattctgtg aataatacgt atcagattta tcttttattc ttactaggaa agtaattatt
       61 aagggagttg atttgaataa tggttagcaa gaataataag agagtatttc tagaaaaaac
      121 aaagaaacga gtattgaagt acagtatcaa aaaattaagt gttggggttg catctgtttt
      181 gattggtgtt ggtcttgtct tgggaacaac tgaactagtt aaagcacaag atgaaatttc
      241 tccaagcagc ccacttgaaa cagcgataag ctccgtacaa gtaggtgaca aagtagcttc
      301 ggggaatact tttcaggaga atcctggtta tacgaaaaat tataactttt cggatttaca
      361 atttagtcct caagaactaa ctggagacac actaaaaggc aatacaattg gatttgaagt
      421 ttacggaaaa cataatattg cagcatcaac taaaaactgg gaaatccgtc ttcaattaga
      481 tgaacgatta gctaaatatg tagaaaaaat tcaggtcgat ccaaagaaag gaattggatc
      541 ttctagacgg acctttgtaa gaattaatga ttcgctgggt agacctacaa atatttggaa
      601 ggtcaattat attcgtgcaa gtgatggatt atttgctggg gcagaaacaa ccgatacgca
      661 aaccgctcct aatggggtaa ttacgtttga aaagagccta gatgaaattt ttaaagagat
      721 aggcatagac aatctcaaga ccgatcgttt aatgtatcga atctacttgg taagtcatca
      781 agacgatgat aaaattgtac cgggtattga tagtacgggc tactttttaa cagattcaga
      841 tgatttctat aatagcttag atgtatctga aaataatcct gaccagttta aacatggatc
      901 agtaagtgca aaatatgaga aacctaatac tcaaacaaaa gatggttcag gatccacagg
      961 tgctaatgga gctataatct tagatcataa gttaacgaaa aattataatt tctcatattc
     1021 atcttccgca aagggcacgc cttggtatgc taattacaaa attgatgaac gattagttcc
     1081 atatgtagcg ggtatacaga tgcacatggt tcaggctgac aaagtaacat atgatgtttc
     1141 gtttgaatcc ggaacaaaag tagctgattt agcaatcgag cgacgggaag gtcatgaaaa
     1201 ttatggcata ggttcaataa ctaataatga tttaactaaa cttatcgatt ttgctaatgc
     1261 aagtccacgt ccagtcgtta ttcgatatgt tttacaattg actaagccat tagatgaaat
     1321 cttagaagat atgaaagcaa cagcacaagt tgaagaaaat aaaccatttg gtgaagattt
     1381 catctttgat tcttggttgt cggatacgaa taaaaaatta atccagaaca cttatggaac
     1441 aggttattat tatttgcaag atattgatgg tgatggaaac cctgacgata aagaagagag
     1501 cggagacacg aatccatata tcgggaaacc tgaattagaa gaagtatatg atgttgacac
     1561 aacagttaag gggaaagtat tcatccacga gttagcggga acaggtcaca aagcccaact
     1621 tgttgataaa gaaggtactg tattagcaga aaaaactatc gctccaaatg aaaaagatgg
     1681 ggctccaatt tcagatactg tagaatttga atttacgggt gtagattcaa gtaaattaat
     1741 cgcgaaagat gaattaaaaa tccaaatcgt ttctccaggt tttgataaac cagaagaagg
     1801 ttcaaccgtt attaaggaat caccaaaagc ggttgataaa caaaccgtgg tagttggatt
     1861 taaaccagat gctaaagaat caattcggaa taataaaaac ttacctgaag atgcagagta
     1921 ttcatggaaa acagagcctg atacttctaa cgttactgat agtacgaaag gtattgtaac
     1981 tgttaagatc ggaaatcgaa ctttcgacgt ggatgtagag tttgctgtaa aagcttctca
     2041 agctatggaa aatgatgcaa catacgtacc tataacaaca actccagaaa cgacagttca
     2101 aagtggaaaa cctacatttg ataaaccaga tgttccttta gctaaagatg ccttttcaat
     2161 ttcagatgtc tataataagt acttcggtaa tgcaagtgtt gatgcaaaca ctggtattgt
     2221 tacattcact ccagctaaag gtgtaggaga atcggagccg attactggaa caattcctat
     2281 taaaattgtt taccaagatg gttctgtagg cacgaccgat ttagcagtaa ctgtaagtaa
     2341 agatatttat gaaaatccag gagaaaacat tcctgcaggc taccacaaag taaccttcac
     2401 cgcagg
//
LOCUS       DACGLI010000136         2350 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.145, whole genome shotgun sequence.
ACCESSION   DACGLI010000136 DACGLI010000000
VERSION     DACGLI010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.145"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..544
                     /locus_tag="IXT22_002910"
     CDS             <1..544
                     /locus_tag="IXT22_002910"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4864210.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(1017..1589)
                     /locus_tag="IXT22_002911"
     CDS             complement(1017..1589)
                     /locus_tag="IXT22_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864211.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1605..2210)
                     /locus_tag="IXT22_002912"
     CDS             complement(1605..2210)
                     /locus_tag="IXT22_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAQ4864212.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          741 a          468 c          358 g          783 t
ORIGIN      
        1 catttcaaaa gagaatctct taaatcagga cttttctact gaaacgatct gtgagaaatg
       61 ggcagctgac attacgtaca ttcctactaa gaaaaatggt tggtgttact tatcttcaat
      121 catggattta cacacgaaaa gaattattag ttatacattt tcaaaacgaa tgactgtgga
      181 ttgtgtcatt caaacattga ataaagcaaa aatacattat cacattccag aaggaatgat
      241 tctacacact gacttgggca gccaatacac agcaagagaa gtggaacaat ggcttaaaac
      301 caacaaaata aggcattctt atagtagaaa aggaacacct tatgataatg ctggaatcga
      361 atctttccat gcctcattga aaaaagaaga agtctacacg actagctact cagattttga
      421 agaagcaaat cgagcgctat ttagctacat tgaaggattt tataaccgaa atcgaatcca
      481 tagctcgatt cactatctaa ccccacagga atttgaagaa ttagcaaaag aaaaaatggc
      541 ttaaccgtct ctactaaaat gtgtccaaga tattgactca aatccagtaa tatcacaata
      601 ggaatgctgt ttattatatt agcagcagtg ctgattttta tgatagttat ttggttctta
      661 aatgaaagat ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca
      721 atagattatt tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg
      781 aacgatatgt gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc
      841 taatatagta agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca
      901 cattttttga gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag
      961 actcatatct agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa
     1021 ctttcttcaa ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct
     1081 tcaacttcct tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt
     1141 gtgattgttg ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt
     1201 tttccttctt gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac
     1261 gtccgtgtca ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg
     1321 atcgttacgt tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga
     1381 gcaaatcgat caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc
     1441 tgattgaatt ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc
     1501 ttctctacgc agttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt
     1561 gagacacgtg catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc
     1621 gtatactcag aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg
     1681 cgatcgtcaa ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt
     1741 atgggacttc gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca
     1801 actttttgca attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt
     1861 ccttctcgaa atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa
     1921 gaagtttgtg gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca
     1981 aatcgaaaat ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata
     2041 tccgaaaata gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca
     2101 tttatttttc cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc
     2161 ttagccaact caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc
     2221 cttaacttta tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt
     2281 tatgtgtcaa aaactattaa gtttctgacc cccgatagat ttttcaagtg tctctatttt
     2341 gcacagtcta
//
LOCUS       DACGLI010000137         2345 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.146, whole genome shotgun sequence.
ACCESSION   DACGLI010000137 DACGLI010000000
VERSION     DACGLI010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.146"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(103..1650)
                     /locus_tag="IXT22_002913"
     CDS             complement(103..1650)
                     /locus_tag="IXT22_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAQ4864213.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1752..2105)
                     /gene="tnpB"
                     /locus_tag="IXT22_002914"
     CDS             complement(1752..2105)
                     /gene="tnpB"
                     /locus_tag="IXT22_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAQ4864214.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2095..2289)
                     /locus_tag="IXT22_002915"
     CDS             complement(2095..2289)
                     /locus_tag="IXT22_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864215.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          660 a          486 c          420 g          779 t
ORIGIN      
        1 tttttatttg gtcttgaaga agaaaagtaa gcgccccata gaacagtacc tgtacgtcaa
       61 ataacccgac ctatagaata gaatcgggaa tgtttggcgt ttttagttac gagaaaaatg
      121 ttgttgtaca tccttgttcc aaggcaacag ttgatctaaa gtttctgctg aaagtacggg
      181 aagatttggt atcttatcaa atagaaactc tagatacttt acaggattca atccgttaag
      241 ttctgctgtt ttatatacac tcagaatgat tcctgaagtt cgtgctcctt caagacttgt
      301 ggaatgcaac caatttttcc gtcctatcac cagctctttg atatttcgct ccgcacgatt
      361 atttgtgagt tctaaacgac catcttcaaa aataggttca aaaccacttc gtagtttaca
      421 cgcatattga acggctgcat ccaacttgga ttttgcaaca ggatctatcg ttgccatcca
      481 ctcataaaaa gcaataaata atggacgcag ttcttgttgc cgacagctta atcgcttctc
      541 aggagaaaag tctttccatt tcttttctag gacaaaccat ttatccaatt gtttgactgc
      601 ttgagctgcg ggaatatccg tgtttttctt tccttttgga attgcttcga aaaatttccg
      661 ccgaacatgc gcgaaacaat agacaagtcg tacactttcc acggcattat acccgctata
      721 gccgtcacag tgtaaatacc ctgtaaactc cttgagaaaa gttttcggaa catctccagc
      781 acgactttcg tcgtggtgat aataaacgat gggatgctga ctgtcttttc ctgtacaaaa
      841 ctgccagtaa taggtatctg ttttggcact ttcaatcaca cgataacttg tttcatcccc
      901 gtgtagaatc tcttcttgat taagatagac tcttaatcgt tctcctaaag ggtctaacgc
      961 gttttgcact gctttaatat gccaattggt gatattatct ctcgaaatat ccaacccatg
     1021 tgtttgtttc caatagttct cttgccgata ggcaggaact ttctgaccaa atttcatccg
     1081 gatcgtttcc gccactaaac tattggaacc taagctatta gaaatcaaag gtttaggaac
     1141 gatcgctttt ttaaaagaag aaagtccttc tttttcgcag cttttacaac aataggtatg
     1201 ttgataatgg gtgagacaat ccaacatagc ctgatggaaa cgaatttctt ctcgtacttt
     1261 tgtccgtccg atatctttca tctgtgaacc gcaatgttca caaaattgtt cttccaaagg
     1321 aaggagatgt tctttctctg ttataggtaa gtgtttgatt ttgtctgctt tcgttcctac
     1381 aactcgttga tgtcctttta ctggaataat ggtggcagct gcttctggaa cacttacaga
     1441 aatttcttca tcactaaaaa gattcaattg cccattcgtt tcctcaaaga gagtctcttt
     1501 agagcgtcca aataatttgt tggttaaata attgaccttt tcattcaata gttggatttc
     1561 agttgtaaga ttctgaatgg tttgttgttg tgcttgattg gttttatggg cttcttgaag
     1621 caactgaagc aacgtatctg tagtttccaa aatttttcac caccttgaat cgaactgatt
     1681 ttgttacaga ataccacaag aaacgcacaa gaaatagggg ttcaacacat tttttgtgtt
     1741 aaccccccag cttaaaaaac tccttttttt cctggcaaaa tagctcgagg ttgatcgata
     1801 cttaatcctt ctaacaacca tcgaacctgt tggttcgtta aggttcgaac ttcgtctttc
     1861 gtccgaggcc attttaactt gccgttttct atccgcttat aacagagaag aaaaccatca
     1921 ccgtcccaat agagaagttt gaaacggtct tgacggttcc cgcaaaataa aaaaacggca
     1981 tcttcgtaaa gctcgagttg atactcttgt tgaataagac tggcaagacc atcaattcct
     2041 tttcgcaaat ctgtttttcc gcacacaata taaatatgtt tggtttgaag taaatcataa
     2101 agcattggac aacagttctt tcaaaatagc ttgaagaata taattgttaa taccgttata
     2161 gatcaaaact tcagaaccat tctctctttt gatgcgcatc gctaacttgg cagccgcggg
     2221 tttacctttt tctggtgcac tcttttcgtt tcctaattgg acaggaacaa tctcatttaa
     2281 tttatacata gaagacctcc agacttcttg atagctcaag tatatcttga ggtgcatttg
     2341 ttagt
//
LOCUS       DACGLI010000138         2270 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.147, whole genome shotgun sequence.
ACCESSION   DACGLI010000138 DACGLI010000000
VERSION     DACGLI010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.147"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            191..445
                     /locus_tag="IXT22_002916"
     CDS             191..445
                     /locus_tag="IXT22_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4864216.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="IXT22_002917"
     CDS             446..763
                     /locus_tag="IXT22_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4864217.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..2257
                     /locus_tag="IXT22_002918"
     CDS             1322..2257
                     /locus_tag="IXT22_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864218.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          429 g          711 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatttat accggaagat tttcaaaact tacagttaga
     1921 aaacatgcgt ttagaagatt tatttagatt agcagaagat gataagtata gatttgaagt
     1981 tttgaaaatt caaaagaatg aactattgaa taagttatat cctgagaatg cgataaaagc
     2041 acattttggt gatgctaatc atatgtatag ttggttcatt cctaaaagat ttagagggaa
     2101 aatcaatgct ggagatcaag tgaaagtact caatcgaaat agtacagatg tcgtaatgat
     2161 aacagatatc tatgtagaag atgaagatat aatcaaatat atgaagcctg tgataaaact
     2221 tgttaataaa aataaaggaa cccgtggtgc tagttaattt tttcctagag
//
LOCUS       DACGLI010000139         2255 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.148, whole genome shotgun sequence.
ACCESSION   DACGLI010000139 DACGLI010000000
VERSION     DACGLI010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.148"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(144..2141)
                     /locus_tag="IXT22_002919"
     CDS             complement(144..2141)
                     /locus_tag="IXT22_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAQ4864219.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          574 a          505 c          411 g          765 t
ORIGIN      
        1 gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc agtttctcgg tatgaagtca
       61 aatttaagca aaaatgtgag aagctatttt cacaaaattt ttcttcatac tcgaaactaa
      121 gcggcttttt cacgacctct tttttatttt gccatgaaca tatcataata cgcgtccatt
      181 atttctttag caatcgtcaa gtttatgtgg tcttgttcgt ctaataagtt cggcaagaca
      241 acactgatgg caatttccgg attgtctgtt ggtccgtatg ccacgatatt actattgact
      301 gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag tccctgtttt tgcggaaagg
      361 tccattttcg cactggctaa tggtttggct gttgtgtaag gatcggtacc atggacaact
      421 tggtggaatc cttcacggag gatcgccata ttttctgcag aaatattgac cgtattttct
      481 actgttgtgc caatttcttt cttcacttca cccaagtttc cattttcgtc attgccatag
      541 atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat tagcgactgt tgaagcatat
      601 tgagctaatt ggattggtgt atatgtgtca aactgtccaa atgccaaatc ggtaaagtta
      661 cctggagcat accattcttt gccattatcc gcattgaact tcttcatata atcaacagaa
      721 cgtgagatcc caggagattc attcggcaaa tcgatcccag tcgttgtacc aagaccaaac
      781 tctttgaaag agtctctcaa ttgctgataa gctttagctt cttcatctaa actaggtagt
      841 cccattccag gtgtatagtc tagtcctaac atctttaacg ccactttgat catatacgta
      901 ttagaagaca attccgatgc tttgactgca tcaagagcaa cttgtccgct tcgattaaag
      961 acagagcttt tttctgaagc accttgcaga cgaatcggct catcaatcaa aacttgattt
     1021 ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac cagccttgac tacagaccct
     1081 ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg tgatttcttt ggaaccttgt
     1141 tcatgactga aaccagtcat tgctagcact tctcctgtct gaggattcat agccactgca
     1201 taagcaccag gcgaatactg tgctttgccg ttgttgatca atgtttgata attccttttc
     1261 aaaatttctt ctacttttga ttggaattct gcattcatag ataacattaa attagaacct
     1321 ttttccccag agaagatttc tttttgattc gaaacatttc cttcattatc aagggaaact
     1381 tcatattggg ttttggttcc ttgcaggaca tcttcatatt gtttttccaa ataactttgt
     1441 cctacacggt cattccgaga ataacctttt gctaggtatt tctctgcttc atctgctgga
     1501 agtccttgct tttcagtcgt cacactgcca agaatacttt tcagtgaact tgctgcatta
     1561 tattctcgtg tccagtctgt gccagtcgaa actcctggaa gttcagaagc gcgttctgcc
     1621 acaacagcta actcttgatc agtaacacca gagtttttga tatagacagt gtttaattca
     1681 tatgcactat tcatccgttt aaagatggta gcaattttta attgctcctc gtttaaatta
     1741 atctcatcag ctgtgacttt attgaccatc gcactatatt gttcgctgtt ccctaattgc
     1801 ttttcttttg ccgaaagtct ttttgtggct tctttcaaat gtttgggatc agccagccaa
     1861 aaatcttttt tatctctatc tgtcagattt tcatctaccg gaacatcgat cagcgagttc
     1921 agcttcgttg cgatttcaag caaatcttta gccgtaactt gtgttcctct cgtatatgtg
     1981 atggcctgat tcgctttatt cgtaactaaa gcttttcctg tggagtcgta gatcattccg
     2041 cgaggagtac tttcttggac cgtaatcgta gaagtagact tcactcgcgc ctccatctct
     2101 tcgccgttca cgatctgcaa ataacccaat ctagcaatca acgcaacaaa taacgtaaat
     2161 ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg accggcgaaa cgttttgttc
     2221 ttaggttctt gtgcaccttt tcttattttt tctaa
//
LOCUS       DACGLI010000140         2251 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.149, whole genome shotgun sequence.
ACCESSION   DACGLI010000140 DACGLI010000000
VERSION     DACGLI010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.149"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..303)
                     /locus_tag="IXT22_002920"
     CDS             complement(<1..303)
                     /locus_tag="IXT22_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864220.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFS"
     gene            765..2147
                     /locus_tag="IXT22_002921"
                     /pseudo
     CDS             765..2147
                     /locus_tag="IXT22_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          831 a          382 c          380 g          658 t
ORIGIN      
        1 ggaaaacttt gcaacagaac cgaaatgagt atagtatgaa ttagtaattt ggttttcatc
       61 taagtttagc tttgatttac taaaattgat atctcgatac atgttcaata catctaatac
      121 aaatcgagaa tcttctttcg gaaatggctc agaaagatca ctccaaattt catcatcata
      181 atgatactcg taaccttctc tcaatatttc gatttttctt tcataataag atctgttttg
      241 gtcctcaaat ttagccaata actcaaattg atttactagt gacaatctct gaaaactgtc
      301 cattaaatgt ttcttcctat cttgttcatt aacaaaaaat tataagccct tacaacgaat
      361 attatatatt aaatttaatt gtaggtgaac acgaatttta taaatattta tggtgttaat
      421 gacaaatgat atccgactcc tcttcatacg ttctggacta tttgctaata gattaaaatt
      481 tcagcatcta tttctgacca taaataaatg agctgccgaa aagctgccaa atcagacttg
      541 aaaataaagg atcaaaaact tttaagtttc tgaccccgta actcacactt caaaatctta
      601 cttaaaaagg agtctgaaag aaaaaaagag tattcaaaat ttttttctaa ctagctacat
      661 cacatctatg cattgacact caaagaacca gaataagtca tcagaaagca agggggtgcg
      721 gacataatcc tggacgaaaa aataaactta ggaggaatgt ccgtgtgttt tcccacaaag
      781 agcgtgtaag ggcaattcag ttatttttaa aatacgattg ctcttatgct gcaaccattc
      841 gagaattagg gtatccgtcg attggtgcac tacggaaatg gtataaagag tatttggaat
      901 ccggagagct ccatcaggag caccgaaaaa aatcaaagta ttctgaagaa caaaaacgaa
      961 tagcggtgaa tcattatttt gaatatggtc aatgttatgc acgaaccatt cgcatgcttg
     1021 gttatcctaa tagagagtcc ttgcggcagc ggtgtgaaga acttgcacca ggagctagaa
     1081 aactccgaaa aagtgcggta aagttaacac aagatcaaaa agaagctgtg ttgaaaaaat
     1141 tctataaacc gcaaactaat aggaaaaatt tagccgaatc tggaggaatt agtagagtta
     1201 ctctatatca atggaaaaac acggttcttg gaaaggattt tccattgtgt atgactttaa
     1261 aaaatcagga aaaacaaaaa gagctacttt taaaggaagt agaagactta caaaaacaag
     1321 tacaccaatt acagctcgaa aaagcattac tcgaaggagc ggctgaactg ctaaaaaaag
     1381 aaaaaggcgt caatcttctt tgtctatcaa atcaagaaaa aacgatattg attgatgcct
     1441 tacgaaatca gttcaccttg aaagagcttc ttcaacagct ccagtttcct aaaagcagct
     1501 atttttatca aaaacaagca cttgagaaac cagataagta ttacaaagaa cgtcaaatta
     1561 attatcacga ttttcaatca taacttctgt gcgtatggtt accgtagaat tcaccaagct
     1621 ttaaaaaata tgggtaaaaa gctttctgaa aaagttgtac gtagattgat gactgaggaa
     1681 aatctatttg ttaaattttc tagacgaaaa aagtattctt cgtatgctgg ggaaatttct
     1741 cctgcacacc ccaatttatt aaatcggaat tttaaagcaa agaagccaaa tgaaaaatgg
     1801 ttaacagata ttactgaatt tagaattctc gcagggaaaa tctacttatc accacttgtc
     1861 gattgttacg atggtgctat tgttagttgg actattggaa caaagccaac ttgcttcact
     1921 ctatgtctaa aaagagttat tcaccagata attcagcgtg cgaaggtttc tttggacgat
     1981 taaaaaacga gatgttttat caacgtgact ggaagaatac aacaatcaat cagtttataa
     2041 acaaattgga tgattatatt cattggtata ataatcaacg aattaagtta tctttaggaa
     2101 ggctaagccc tcttcaatat cggaagaagc aaagatatat ttgttaaaaa ggtccaaaaa
     2161 aaatatccgc accccctttt ttttgtaaaa aactattgca caatacaagt agcctacggc
     2221 tatcgaaatt tccataactt tcgagcaaga a
//
LOCUS       DACGLI010000141         2226 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.150, whole genome shotgun sequence.
ACCESSION   DACGLI010000141 DACGLI010000000
VERSION     DACGLI010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.150"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            5..397
                     /locus_tag="IXT22_002922"
     CDS             5..397
                     /locus_tag="IXT22_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4864221.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            398..1837
                     /locus_tag="IXT22_002923"
     CDS             398..1837
                     /locus_tag="IXT22_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HAQ4864222.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1967..>2226)
                     /locus_tag="IXT22_002924"
     CDS             complement(1967..>2226)
                     /locus_tag="IXT22_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864223.1"
                     /translation="KYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          888 a          195 c          382 g          761 t
ORIGIN      
        1 cctattgaaa ctattgttta ttgatgataa tatggttttt gatattgata atttaaaagg
       61 atttcttaat gataccagtt catttgggtt tatagctaaa gaaaataata aaattatagg
      121 atttgcatat tgctatacac ttttaagacc tgatggaaaa acaatgtttt atttacactc
      181 aataggaatg ttacctaact atcaagacaa aggttatggt tcaaaattat tatcttttat
      241 taaggaatat tctaaagaga ttggttgttc tgaaatgttt ttaataactg ataaaggtaa
      301 tcctagagct tgccatgtat atgaaaaatt aggtggtaaa aatgattata aagatgaaat
      361 agtatatgta tatgattatg aaaaaggtga taaataaatg aatatagttg aaaatgaaat
      421 atgtataaga actttaatag atgatgattt tcctttgatg ttaaaatggt taactgatga
      481 aagagtatta gaattttatg atggtagaga taaaaaatat acattagaat cattaaaaaa
      541 acattataca gagccttggg aagatgaagt ttttagagta attattgaat ataacaatgt
      601 tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg attatcatta
      661 tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc caaattattg
      721 gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga aaaaagaaag
      781 aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa taagggcata
      841 ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac acgagggcaa
      901 aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa atgttaaggc
      961 aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta ttgaaataat
     1021 cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt ttaaaacaaa
     1081 atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata attttttaaa
     1141 tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata ttagtgatga
     1201 attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag aaatttattc
     1261 tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt ttttaagaca
     1321 aatgcacggt ttagattata cagatattag tgaatgtact attgataata aacaaaatgt
     1381 attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg atatagaaaa
     1441 agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg agggtaaaaa
     1501 gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca ataatagatt
     1561 aactggaata attgattttg gagattctgg aattatagat gaatattgtg attttatata
     1621 cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata tattaagaat
     1681 gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg aagaatatta
     1741 tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta tcgaaaatgg
     1801 tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat gaaaagctat
     1861 tataaaagac attagtatta aatagtttaa aaaaatgaaa aataataaag gaagtgagtc
     1921 aagtccagac tcctgtgtaa aatgctatac aatgttttta ccatttctac ttatcaaaat
     1981 tgatgtattt tcttgaagaa taaatccatt catcatgtag gtccataaga acggctccaa
     2041 ttaagcgatt ggctgatgtt tgattgggga agatgcgaat aatcttttct cttctgcgta
     2101 cttcttgatt cagtcgttca attagattgg tactctttag tcgattgtgg gaatttcctt
     2161 gtacggtata ttgaaaggcg tcttcgaatc catcatccaa tgatgcgcaa gcttttgaat
     2221 attttg
//
LOCUS       DACGLI010000142         2154 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.151, whole genome shotgun sequence.
ACCESSION   DACGLI010000142 DACGLI010000000
VERSION     DACGLI010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.151"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..917)
                     /locus_tag="IXT22_002925"
     CDS             complement(<1..917)
                     /locus_tag="IXT22_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAQ4864224.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVG"
     gene            1082..2095
                     /locus_tag="IXT22_002926"
     CDS             1082..2095
                     /locus_tag="IXT22_002926"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAQ4864225.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
BASE COUNT          722 a          396 c          447 g          589 t
ORIGIN      
        1 tttccgacag caattggact gttcggaatc gtgaaaccag aagctgtcaa ttctttgaca
       61 taggagctca agaactcttc ttttaaggca tattgttttc cgttcaatgc gtagcagacc
      121 gtacgaatcg caaaattgct gtttccaaga tccactaatc caaagataga aggttcagtt
      181 tggagctctt cttggtattt ttcagctaat gtacgattta ctcgatcaat gatctcatag
      241 attttgtcat atccttcttc aggaacaatc cgaatatcta aaagtacttg catatttgca
      301 cgagagagat tgctgatcgt ggtgatgttt cgattcggga tgaaatggac agtaccatcc
      361 gttgctttca gctgaagggt acggatacca acagatacga cggttccttc aatcgttaag
      421 tttgctagct tgatgtagtc cccaacatcc atctgttgtt ccatgataat aaaaaatccg
      481 gtaataacat cactcatgaa cccttgggca ccaagaccga ttgccacacc tgcaattccg
      541 gcaccagcca aaagtgatcc gatcggcaca ccgatagcag ataaaattgc atagataaaa
      601 aagaaaccaa gggtataatg aaaaatagta tttaaaagac tatgtaaagt ctttaagcgg
      661 ctctcgttta gaatggcttt tttagaatac tgattaaaag acttatcaat cagatatttt
      721 cccacacggt gaagaatcca aaaaaggacg atcaaaaaaa tcagatataa acttttttgg
      781 ataaaggcag ccaaaatggc gtcccaatca atcccgtccc aaaaccgctg aaacgcattt
      841 actttgctga cagcttgatc tgtcaatgtc tcgccagaag agtctgtcgt accggcagtt
      901 gctaataatg aaaacataaa atcctctttt ctaaaatttg attctttctg tattgtacca
      961 agaagttttc aaaaaaggaa atagcaaaaa taactataat gaaggaaaaa agctgaaaat
     1021 aaaatgacaa ataatatgga taatgataaa atgtggagaa aataacgaag gtggtaagta
     1081 tatgcaaatc gattggaaca atctaggttt ttcttatatc aaaactcctt ggcgttttat
     1141 tgccaaatgg aaagacggac aatgggaaga aggagaattg acagaagata attacctgac
     1201 gattcatgaa ggctctccag cgcttcatta tggtcagcaa tgttttgaag gtctaaaagc
     1261 ttatcgtcga aaagacggca aggtcaatct ctttcgacct gaacaaaata gtcgacggat
     1321 gaatcaaagt gctagacgat tgctgatgcc aatggtccct gaaaagatgt tcgttgatgc
     1381 tgtcaagcaa gtggtaaaag caaatgaaga ttttgtgccg ccctatggaa caggcgctac
     1441 attatacttg cgccctttac tgattggggt cggtgaaaac attggtgtcc atccagctcc
     1501 agaatattta tttgtcgtct tctgtacgcc agtaggagcg tatttcaaag gtggactaaa
     1561 accaacgaat tttattgtat ctgattacga tcgtgctgct cctaagggga ctggtgcagc
     1621 aaaagtcggc ggaaattacg cagcgagttt acttccagga acagaagcaa aagaactgga
     1681 ttactcagat tgtgtttatc ttgatccagc cacacatacg aaaatcgaag aagtaggtgc
     1741 agcaaatttc tttggaatta caaaagacgg aaaattcatc actccgcaat cgccctctat
     1801 cttaccaagt atcacgaaat attccttgtt gcagttagct gaagaacgac taggactgca
     1861 agcaattgaa ggagatattt tcattgatga tctagatcaa tttgcagaag ctggtgcatg
     1921 tggtacagcg gctgttattt ctccaatcgg tgggatttat cacaataaca atcttcatgt
     1981 attttatagt gaaacggaag taggaccagt aacaaaacgg ttgtatgatg aattgacagg
     2041 tattcaattt ggagacatag aagcaccaga aggctggatt gaagtcgtgg aataatttca
     2101 aagtaatgag ttgaaaaaaa cgtaaaaaga aaaaatcagg aagagacttt aaaa
//
LOCUS       DACGLI010000143         2056 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.152, whole genome shotgun sequence.
ACCESSION   DACGLI010000143 DACGLI010000000
VERSION     DACGLI010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.152"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            493..714
                     /locus_tag="IXT22_002927"
     CDS             493..714
                     /locus_tag="IXT22_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864226.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="IXT22_002928"
     CDS             715..972
                     /locus_tag="IXT22_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864227.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="IXT22_002929"
     CDS             complement(1108..1710)
                     /locus_tag="IXT22_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4864228.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="IXT22_002930"
     CDS             complement(1777..1932)
                     /locus_tag="IXT22_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4864229.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DACGLI010000144         2003 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.153, whole genome shotgun sequence.
ACCESSION   DACGLI010000144 DACGLI010000000
VERSION     DACGLI010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.153"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..378
                     /locus_tag="IXT22_002931"
     CDS             <1..378
                     /locus_tag="IXT22_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4864230.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IXT22_002932"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IXT22_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4864231.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="IXT22_002933"
     CDS             1859..>2003
                     /locus_tag="IXT22_002933"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4864232.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DACGLI010000145         1990 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.155, whole genome shotgun sequence.
ACCESSION   DACGLI010000145 DACGLI010000000
VERSION     DACGLI010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.155"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(211..1893)
                     /locus_tag="IXT22_002934"
     CDS             complement(211..1893)
                     /locus_tag="IXT22_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4864233.1"
                     /translation="MNTIIKQIEKGKPFFEKISRNIYLGAIRDGFLTAMPAILFSSIF
                     IMIAAVPEVFNVTLPEAFSTWLWKVYGYSMGLVGLLVVATTARCLANSMNRQLSDSGK
                     QINEVSVMLASICGFVMMAADQIDGGIATDYLGTKGLLAAFVSAFVTVNVYKFCVKRD
                     LTIRMPKEVPGTITQMFRDIIPFSIAVFIAVLIDTGVRQFFGTSFAAGVIQLLQPLFS
                     AADGYVGIAIIWGAMAMFWFVGVHGPSIVEPAIAAIIYANVETNFELFKNGAQASKVL
                     TVGLGNFVGTMGGTGATLVVPFLFMLFAKSKQLKAVGKASFIPVSFAVNEPLLFATPI
                     ILNPYFLIPFLLAPIANVWIFKLFVDVLGMNSFISVLPWATPAPIGLVLGTGFSVLAI
                     VLAVVLIVVDAIIYLPFVKAYDSELVEQELKNIAAEEVKEELVEEIQEVGATAAVIVD
                     EAKASVGEGKRVLVLCAGAGTSAMLANALEEGAKETGVNLSAKAGAYGSHYDMMKNFD
                     LIVLAPQVNSYLDDLRKDADKLGIKVIATKGAEYINLTRDPKGAVDFVLKQF"
BASE COUNT          673 a          439 c          293 g          585 t
ORIGIN      
        1 gtcatttgta ctcactcctt attaattctt tggtcggaac tattttgagt gtagcacaaa
       61 tgatcttttt agttgtctag cttaatttta caatcgacgc ctcaaaaaga atacccgaaa
      121 tttaaacagc aaaaaaagat agcgcttacc attgtgttta agataaaacg ctagctaagt
      181 tggctagcgc tttattaatc taagcaagct ctaaaattgc ttcaatacaa aatcaactgc
      241 tcctttagga tcacgtgtta aattgatata ttctgcacct ttagttgcaa ttacttttat
      301 ccctaatttg tctgcatctt tacggagatc atccaaatag gaattcactt gaggtgctag
      361 aacgattaaa tcaaaatttt tcatcatatc ataatgagaa ccataagctc ctgctttagc
      421 agaaagatta acacctgtct cttttgcgcc ctcttctaat gcattagcca acattgcact
      481 cgttccggca ccagcacaaa gtactaaaac gcgctttcct tcaccaaccg atgcttttgc
      541 ttcatcaact ataactgccg cagttgcacc aacttcttgg atttcttcga ccaattcttc
      601 ttttacttct tctgcagcaa tgttttttaa ctcttgttct actaattcag aatcataggc
      661 cttaacaaaa ggtaaataaa taatcgcatc gacaacaatc aatactaccg ctaatacaat
      721 cgccaacaca ctaaacccgg ttcctaaaac caagccaatc ggtgcgggcg tcgcccaagg
      781 caatacggat ataaagctat tcatccccaa gacatcgaca aaaagtttga atatccatac
      841 gttagcgatt ggtgctaata aaaatggaat tagaaagtac ggattcaaaa taataggagt
      901 agcaaatagt aacggttcat ttaccgcaaa cgaaactgga ataaatgaag ctttaccaac
      961 tgctttcaat tgttttgatt tagcgaacaa catgaacaga aaaggaacaa ctagtgtcgc
     1021 tccagtacca cccatcgttc caacaaagtt tcctagacca actgttaata cttttgaggc
     1081 ttgtgcaccg tttttaaata attcaaagtt agtttctacg ttcgcataaa taattgcagc
     1141 aatcgctggt tcaacaatcg atggtccatg aacaccaaca aaccagaaca ttgccatggc
     1201 tccccaaatg attgcaatac cgacatatcc atcagcagca ctaaataatg gctgcaataa
     1261 ttgaattaca cctgctgcaa atgatgttcc aaaaaattga cgaactcccg tatcaatcaa
     1321 aacggcaata aatactgcaa ttgaaaaggg gataatatct ctaaacatct gtgtgattgt
     1381 tccgggaact tcttttggca tacggatcgt caaatctctt ttaacacaga atttatacac
     1441 atttacagta acaaacgcag aaacgaaagc tgctaataat ccctttgtcc ctaaataatc
     1501 agtagctatc ccaccatcaa tttgatcagc tgccatcatt acaaaaccac aaattgacgc
     1561 taacataaca gaaacttcat taatctgctt acctgaatca gataattgac ggttcattga
     1621 attagctaaa catcgagctg ttgtagcaac aaccaaaaga ccaactaatc ccattgaata
     1681 accataaact ttccaaagcc acgtcgagaa tgcctctggt aacgtcacgt taaatacttc
     1741 tggaacagcc gcaatcataa taaaaatact tgaaaataga atagctggca tagcagttaa
     1801 aaagccatcg cgaattgccc ctaaataaat attacgtgag attttttcaa aaaacggttt
     1861 tcccttctca atttgcttaa taatcgtatt catttttctt ctcctatgct ttagcaaatt
     1921 tttctttgta caattcaaca aaatcattga taagttcggt tctgttgcaa agttttccaa
     1981 aaaatctatt
//
LOCUS       DACGLI010000146         1930 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.157, whole genome shotgun sequence.
ACCESSION   DACGLI010000146 DACGLI010000000
VERSION     DACGLI010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.157"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..435
                     /locus_tag="IXT22_002935"
     CDS             <1..435
                     /locus_tag="IXT22_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4864234.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="IXT22_002936"
     tRNA            complement(759..842)
                     /locus_tag="IXT22_002936"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="IXT22_002937"
     CDS             1370..1870
                     /locus_tag="IXT22_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4864235.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
BASE COUNT          625 a          364 c          329 g          612 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat
//
LOCUS       DACGLI010000147         1842 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.158, whole genome shotgun sequence.
ACCESSION   DACGLI010000147 DACGLI010000000
VERSION     DACGLI010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.158"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..224
                     /locus_tag="IXT22_002938"
     CDS             <1..224
                     /locus_tag="IXT22_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864236.1"
                     /translation="TESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDT
                     YTYDDTEEIQNELDRKRMPYQRFERKKGQ"
     gene            605..784
                     /locus_tag="IXT22_002939"
     CDS             605..784
                     /locus_tag="IXT22_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864237.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            915..1184
                     /locus_tag="IXT22_002940"
     CDS             915..1184
                     /locus_tag="IXT22_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4864238.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            1177..1434
                     /locus_tag="IXT22_002941"
     CDS             1177..1434
                     /locus_tag="IXT22_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4864239.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          677 a          249 c          359 g          557 t
ORIGIN      
        1 ggacggaatc tatcgtgtta atgggaatgg attatgaact cactgtaccc gaagcatttt
       61 tgagggaata tgtagaagaa gtagataacc caggcgacga ctggtacacg actttaactg
      121 attttttaga cacctacact tacgacgata cagaagaaat ccaaaatgaa cttgaccgta
      181 aacgaatgcc atatcaacga tttgaaagga aaaaaggtca ataaccattt ataccgaaaa
      241 gtgaggatgt gtgaaataag aacaaaaaac cttgaaatta agggaatggt tcttatttcg
      301 caccaatcga tccaaccgcc cccgccgctt aggtggtgcg aaataagcgg gcaaagcccg
      361 ataacctaag agaaagaagg agatccatat gaataaaatc attcctctat tgttcgtact
      421 gtttgttggc gagatactta tgcgtcatgg tgcagctcta catttaaact tcgtagtatt
      481 cttaggaata ctggtatttt gtttgatctt ttggcgcttt gtgttaaccc ttgtgagtct
      541 aatattcaag ttgattgcag ccatattttt aatagggtta tttcgatgaa aggagagagt
      601 actaatgcca attgcaatag gaaataaacg gttacccgtg acgttggatg aaaagagaca
      661 aaaagaattg cagcaactaa agcagaagta cggcaaaagt gaatccagga ttatgtgtat
      721 tgcgttagat ttattgattg cccaagaaaa agcaggattt gaggtaccag cactcaaaaa
      781 gtgacgtcac tttttatcct aaaaactaaa agtgatagca cttttaatta taagaagtta
      841 gaatattaat catttgctta attgtacaat ataatgtaca attgttttat agaaataaat
      901 aaggggtgaa aggaatggaa gcagtagctt attcaaattt ccgccaaaat ttacgtagtt
      961 atatgaaaca agttaatgag gatgctgaaa cacttattgt aacaagtaaa gatgtagaag
     1021 atacagttgt tgtattatca aaaagagatt atgattctat gcaagaaacg ttgagaacac
     1081 tttctaataa ttacgtcatg gaaaaaattc gtcgaggaga tgaacaattc tccaaaggtg
     1141 catttaaaac acatgactta atcgaggttg aatctgatga ttaaggcttg gtctgatgat
     1201 gcttgggatg attatcttta ttggcatgag caaggaaaca aaagcaatat aaaaaagatt
     1261 aacaagttaa taaaagatat cgatcgttcc ccctttgctg gattaggaaa acctgagcca
     1321 ttaaagcatg atttatctgg aaaatggtcc agaagaatta cagatgaaca tagactgata
     1381 tatagagttg aaaatgaaac gatatttatt tattctgcaa aagatcacta ttaaccaatc
     1441 ggaagtaagg aaagggtcag aaacttaaaa gtttttgatc cttattttat ttaccctagt
     1501 catttaaaaa gctaatatag cttagtgttg attgttatta atgaatgtgt ttgttacgcg
     1561 tattacggat ataaggttag taaaatcatt tctaaagttg aggaaaagta aatataaatg
     1621 gcttaaattt caacaatttg aagttgaata gatatgttat aatactattg tagtgtggga
     1681 tgttagttac taaaggatga cgcttatata tatgactgaa tagaataagc aataggttta
     1741 ataatctatt ttaaattttt tgtactagtt ttagttaatt agcaaaaaca acaaaaataa
     1801 acttctcata gaatttagct aaaaattaat gatttattta ca
//
LOCUS       DACGLI010000148         1656 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.159, whole genome shotgun sequence.
ACCESSION   DACGLI010000148 DACGLI010000000
VERSION     DACGLI010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.159"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..619
                     /locus_tag="IXT22_002942"
     CDS             <1..619
                     /locus_tag="IXT22_002942"
                     /inference="COORDINATES: protein motif:HMM:TIGR00350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4864240.1"
                     /translation="VDIIGYDTYDKINHAYAFGGVAMTINTIQAYLDIPIDFFVTLNM
                     QGLEQIVDSIGGITLTPTATFTQDSYSFYQGEIINLDGKASLAYSRNRHADDSGDYGR
                     QARQREIIMAIIEKGTKVTTLATKIPSLIKSLQGNMTTNLSVDDMWTIINKYSTALGN
                     IEQVQLKGEGQLLDDGIYYEMINEESLEEVQNILQKQLDYHLNID"
     gene            669..1193
                     /locus_tag="IXT22_002943"
     CDS             669..1193
                     /locus_tag="IXT22_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864241.1"
                     /translation="MQNDIRGKIKKSRHIKGISQSEVAKYLNISRQSISKWENDTSSP
                     DINNLTLLSSLYEISIDDLLKEKKEVKKNIKENSIEIIESKNKLIYLKNNTNRDEGLV
                     LLLISLIGCLISPLGLIIAPVVLKRNKATNTFYKGVIAASVICFTVSLFVSYGHFSNI
                     FHWGGSTNVEYIEN"
     gene            complement(1190..>1656)
                     /locus_tag="IXT22_002944"
     CDS             complement(1190..>1656)
                     /locus_tag="IXT22_002944"
                     /inference="COORDINATES: protein motif:HMM:NF037267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864242.1"
                     /translation="LRQVLLVVTLCLSFFLFEVNTVEAYVANNGVYYNLIQGGTQEFM
                     EVDEEGNPILIRVEEVPGLSLFSVNNGNYKISGSKFGMWKANYYVTVSNNQFIRAYSP
                     SAVAVTGSFTSTRLSLVSSKKASYTLEWKAGILSSNSYLDATLTDNSINITY"
BASE COUNT          596 a          266 c          287 g          507 t
ORIGIN      
        1 tgtcgatatt atcggttatg atacttacga caaaattaac catgcctatg cctttggtgg
       61 agtagccatg actataaata caatacaagc atacttagat atacctattg acttttttgt
      121 aacgttaaat atgcagggtc tagaacaaat tgttgattct attggaggaa taactcttac
      181 tccaactgcc acttttacac aagatagtta ttcattttat caaggcgaaa ttattaactt
      241 agatgggaag gcttccttag cgtactctcg aaatcgtcat gcagatgatt caggtgacta
      301 tgggagacaa gctcgtcaaa gggaaataat aatggcaatt atagagaaag gaactaaagt
      361 tactacacta gcaactaaga taccttcact cattaagagt cttcagggaa atatgactac
      421 taatctgtca gttgacgata tgtggactat tattaataaa tattccactg ctttaggaaa
      481 tatagagcaa gttcaattaa agggggaagg acaactactt gatgacggaa tatactatga
      541 aatgattaac gaagaatctt tagaagaagt tcagaatatc cttcaaaaac aactagatta
      601 tcacttgaat atagactaaa taatctattt cttaatatcc aataaataaa agtcattaat
      661 aggagaggat acagaatgac attaggggaa aaattaaaaa atcacggcat ataaaaggca
      721 tctctcaaag tgaagtagca aaatatttaa atatatctag acaatctatt tctaaatggg
      781 aaaatgatac tagttcccca gatataaaca acttaacttt attaagtagt ttatatgaaa
      841 tctctatcga tgatctttta aaagaaaaaa aagaagttaa aaaaaatata aaagagaata
      901 gtatagagat aatagaatct aaaaataaat taatttattt aaaaaataat acaaaccgag
      961 atgaagggtt agttttattg ctcatttcct taatcggctg tttgatttct cctcttggac
     1021 taattattgc gcctgttgtt ctgaaaagaa ataaagcaac aaacactttt tataaaggag
     1081 tgattgctgc ttcagtcatc tgttttacag taagcctgtt tgtctcctat ggacatttta
     1141 gtaatatctt tcattggggc ggctccacta acgtggaata tattgagaac taatacgtaa
     1201 tattaatgga attatctgtc agtgtagcat ctagataaga gttactagat aaaattccag
     1261 ctttccattc taatgtgtag ctagcttttt tgctggagac gagagacagt ctcgtgctag
     1321 taaaggatcc ggtcactgcg actgcagaag gggagtaggc cctaataaat tggttattcg
     1381 agactgtcac atagtaattt gccttccaca ttccaaattt agatccagat attttataat
     1441 ttccgttgtt gacggagaac agggagagcc cgggaacctc ttccacacga atcaagatag
     1501 gatttccttc ttcgtctacc tccatgaact cttgcgtgcc accttggatt aagttatagt
     1561 agactccatt atttgccaca tatgcttcta cagtgtttac ttcaaataaa aagaaagata
     1621 aacataaagt aacaaccaat aaaacttgtc tcaaaa
//
LOCUS       DACGLI010000149         1640 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.160, whole genome shotgun sequence.
ACCESSION   DACGLI010000149 DACGLI010000000
VERSION     DACGLI010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.160"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..212
                     /locus_tag="IXT22_002945"
     CDS             <1..212
                     /locus_tag="IXT22_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864243.1"
                     /translation="VLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYD
                     DTEEIQNELDRKRMPYQRFERKKGQ"
     gene            593..772
                     /locus_tag="IXT22_002946"
                     /pseudo
     CDS             593..772
                     /locus_tag="IXT22_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            834..1018
                     /locus_tag="IXT22_002947"
                     /pseudo
     CDS             834..1018
                     /locus_tag="IXT22_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, HicA family"
     gene            1052..1483
                     /locus_tag="IXT22_002948"
     CDS             1052..1483
                     /locus_tag="IXT22_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAQ4864244.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          560 a          261 c          338 g          481 t
ORIGIN      
        1 tcgtgttaat gggaatggat tatgaactcg ctgtacccga agtatttttg agggaatatg
       61 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagata
      121 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
      181 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gagaatgtgt
      241 gaaataaaaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc
      301 caaccgcccc cgccgcttag gtggtgcgaa ataagcgagc aaagcccgaa aacctaagag
      361 aaagaaggag atttatatga acaaaattat tcccttatta ttagtcctat ttgttggaga
      421 aatacttatg cgacttagtg cagctgtaca tttaaacctc gcagtatttt tggtaatact
      481 aatgttttgt ttgatctttt ggcgatttgt attagccctc gtaagtctac tattcaagat
      541 gattgcagcc atatttttca taggattatt tcgatgaaag gagagagtac caatgccaat
      601 tgcaatagga aataaacggt tacccgtgac gttggatgaa aagagacaaa aagaattgca
      661 gtaaccaaag cagaagtacg gcaaaagtga atccaggatt atgtgtattg cgttagattt
      721 attgattgcg caagaaaaag caggatttga cataccagca ctcaaaaagt gatcgcactt
      781 tgcgcacgtg ttaatacgtg ttataattat tttgtaagga ggtatagtgc acaatgccac
      841 ttacgggaaa agaaatgctt aagttattga aaaaaatggc tgggttgagc gaaggcaaga
      901 gggatttcat catcatcttt ataaggatgg tgttagaatc actgttcctg ttcatgccaa
      961 tcaagatctt ggccgaggac ttgagcgaaa aattttaaag gatgcgggat tgaaataatc
     1021 tcgcattcga ttaaagaaag gattgactga aatgttaagt gagcctttag caaaaaccta
     1081 tcctgctatt tttagcccag aagaaggtgg tgggtacttt attgaatttc ctgatgttca
     1141 aggtgcttac acaggaatta acgaagacga tatatcttat ggaattgcta tggcacaaga
     1201 ggtgttaggt atggttttag cagattatat tgagcatgaa gatctacttc cagaaccaac
     1261 accaatcaat aagatttctg ttgaagatga ttcttttact actttaattc gtgtagatgt
     1321 tgccaaatat ttgaaagaca cagaacttgt caaaaaaacc ttaacaattc ctcaatgggc
     1381 ggataagcta ggcaaaaggg ctggcataaa tttttcagtc cttctaacag aatcaattgc
     1441 agataaagca gataacattc ttcgttctgg aagaaataat tagaactcaa aagggtcaga
     1501 aacttaaaaa tctttggctt ctttttttac tacaaagatg gcttctttaa attatttgcc
     1561 tgattgattt aaaaaaattg cgcaaagact acgagctaat taagttgctc gtggtctttt
     1621 tttatgaaaa ctttttagat
//
LOCUS       DACGLI010000150         1636 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.161, whole genome shotgun sequence.
ACCESSION   DACGLI010000150 DACGLI010000000
VERSION     DACGLI010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.161"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(183..1502)
                     /locus_tag="IXT22_002949"
     CDS             complement(183..1502)
                     /locus_tag="IXT22_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAQ4864245.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DACGLI010000151         1603 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.162, whole genome shotgun sequence.
ACCESSION   DACGLI010000151 DACGLI010000000
VERSION     DACGLI010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.162"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            90..1556
                     /locus_tag="IXT22_002950"
     CDS             90..1556
                     /locus_tag="IXT22_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAQ4864246.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          445 a          292 c          333 g          533 t
ORIGIN      
        1 tttatatttc ttaaataagt tttttagtta aatttttcgg taaagatgta taatattttc
       61 tgaaaattta aagaattggg gtatagatta tggaaaaaca gcaagacaag ggcttcttcg
      121 ggcagccgaa gggattgtca actttgttct tcactgagat gtgggaacga tttagttatt
      181 acggtatgcg tgcattactt atctattata tgtacgatac agttgccaac gggggacttg
      241 gattaccacg agcaacagca ttagctatca tgtcgatcta cggatctttg atctacatgt
      301 ctagtatcgt cggcggatgg gtatctgacc gagtgttagg agcaaaacgc actgtattct
      361 tcggtggagt tttcattatg cttggccaca tcgtcttggc tttaccattt ggtgtaagta
      421 cattgtttgt ttcgatggca ttgattatta tcggaaccgc ctttttgaaa ccaaatgttt
      481 ctggcatggt cggacatctt tattcaaaga ctgacttgcg aagagatgca ggattttcga
      541 ttttttacat gggtgtcaac ttaggggcat tattagcacc actaatcgtt ggtacaatcg
      601 gtcaagaata taactatcat ttagggttct ctttagctgc tattgggatg ttctttggat
      661 tattacaata catcatccaa ggacgcaaga cattagacgg agtgggtaca acaccgccga
      721 atcctttgac aactgaagaa cgtaaaggat tcatccgtaa cttgatcatc gcacttgttg
      781 ttatcgctgc agtattcggc ggggcacaac taactggtca tctgacaatt gacttttttg
      841 tcaatacaat cagtgtattg gggattatct taccgttgta ttactttatc aaaatgctga
      901 cttcaaaaga tgtaactgct gaagaaaaac caagagtatg ggcttatatc ccattattcc
      961 ttgcagcaat cattttctgg tcattacaag aacaaggttc atctatctta gctttatttg
     1021 ctagtgaacg tacacaatct acgctatttg gtgtaacgat ccaagcaagc tggtatcaat
     1081 cattgaatcc aattttcatc tttattctga caccagtatt cgtaacgatg tggacgaaac
     1141 ttggtgaacg tcaaccatct acagtagtga aattctctct tggactttta tttgcaggat
     1201 tatcgtactt gctattgatg ttgccgggta tgctttatgg tacaagtgga aaagtaagtc
     1261 cattgtggtt gttgggaagt ttcttcatcg tggttattgc tgaattgtgt ctttcaccag
     1321 ttggtttgtc tgtgacaaca aaattagcac cacgagcatt tgaatcacaa acaatcgcta
     1381 tttggttctt agctgatgct tcttcacaag caatcaatgc acaaattgca cgcttctaca
     1441 caccgggaac agaatctgct tacttcggta ttatcggtgc agtagcaatc gtcggtggta
     1501 tcttgctatt tactgtgaaa gaaccaatca aaaaactaat gggctctatt cattaatcaa
     1561 tgaacataaa aacaggaatt gcttatttgc agcagttcct gtt
//
LOCUS       DACGLI010000152         1536 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.163, whole genome shotgun sequence.
ACCESSION   DACGLI010000152 DACGLI010000000
VERSION     DACGLI010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.163"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..>1536)
                     /locus_tag="IXT22_002951"
     rRNA            complement(<1..>1536)
                     /locus_tag="IXT22_002951"
                     /product="23S ribosomal RNA"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DACGLI010000153         1534 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.164, whole genome shotgun sequence.
ACCESSION   DACGLI010000153 DACGLI010000000
VERSION     DACGLI010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.164"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            7..624
                     /locus_tag="IXT22_002952"
     CDS             7..624
                     /locus_tag="IXT22_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864247.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          580 a          189 c          234 g          531 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattttctac gttttccttt tcatatatat taaatattac ggaaaattat
      841 ataaactaat ttagtgtttt gtttgtaatt cctaattttg ctccactttt agataatttt
      901 taggtctatt taactcatca gacattctat gctcattttt ctccaaattt gtttcaactc
      961 tttcgtactt aattttgcgt atttgaaaat tcttctttta gagtactttt attacgatac
     1021 tagtatgata tatatctata gcaaacagtt aaaatcttcc taaaataagc gaatagcatt
     1081 cctaaaacct ataaaatttt tagatgaagc gacaagtgga caattaataa actacttgaa
     1141 catgaaatta tggatcacct ttcaaattta gaaaatggaa ttcttatact tattgcgcaa
     1201 catttattga ttgcaaaatt atgtgacaaa aaaaactagt agaagaaaga ataatggctt
     1261 gataataaag tactacctat taaaggtagt actttattta atttagtata aattaacata
     1321 ctactatatt ttaggtttca tattatataa attaataata tactaccatt tgttggtagt
     1381 ataatttaaa ggtaataagt tattctttta ttactatgtt tgggttttat agcaaagaaa
     1441 gtttaataag agtttggacc tagcaaacaa tattaatgag gtcattaaat cttattatct
     1501 ttagtgatat aacgaaatat ctacacagac aaaa
//
LOCUS       DACGLI010000154         1530 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.165, whole genome shotgun sequence.
ACCESSION   DACGLI010000154 DACGLI010000000
VERSION     DACGLI010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.165"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            89..940
                     /locus_tag="IXT22_002953"
     CDS             89..940
                     /locus_tag="IXT22_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864248.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            961..1173
                     /locus_tag="IXT22_002954"
     CDS             961..1173
                     /locus_tag="IXT22_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864249.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT          570 a          201 c          310 g          449 t
ORIGIN      
        1 acttaaaaaa ttggttcatt gagcaaccta tcgctgctaa agtagcaaag gaaaacgtta
       61 aaggaaagaa tttagggaag aaatcgaaat gaaatcggac gactggattg aacacacctg
      121 gcttcctctg aaaagaaata gcaaacgaaa gaaattttgg gtattgcaat tatggccatt
      181 aggaaaactt tgtagttacg gggcacgact tattcttgat ttaaccgttt actcgattgg
      241 agtatttgga acggcttatt acttgataaa tgatcccaat aggattgcag catcagacat
      301 ttttacagtg ctaatgacgt tgatttttgt catgctattg tctattttta ctcaattagt
      361 catgcaattt accaggcaaa aattaacagc aggaaaactt ttcaaaagcc tattcgattt
      421 aattgttgta aatgcaattc tagcgacttt aataaaacaa attgaacaat ctggaagaac
      481 aacaaaagga gtgaaggatt ttttattgac gtttattcac tttgtaaatg gacacatgta
      541 tttgtttgaa gtgggtatta ttctcttttt tgtcgggtat gtatccacga aacttattaa
      601 acgttcaatt gaaaaagaaa ttgaaattga cctgattccg acacttcttg gttatgagta
      661 caatgttgat tttggaagat atgacgaatt gatcaatacg gatatcgttc acacgagtat
      721 ccatgaatct actgttaagg gcatcagatc tattttaaaa aatggccagg aaatgaaagc
      781 aatagatcga agaaaagaga tctacaattt ttatgaagtc gaagcaagcc tacgatatgg
      841 catcggaaaa ttgtggttag atggaagtaa tattcgtcaa aacaaaccat acattttttg
      901 gaacagtagt gatttagaac ttccaatgaa agataaataa ttatggagaa tcgtttgaaa
      961 atgattcctc tatacaggat tgtgcttata gttggcatgg agttaaaaac cttaaagaag
     1021 gagcagttat tcaaagtgaa agaacgtcat aatcagttac tatgtagtaa aacgggtacg
     1081 atgaacattg aataccgaac agaatattta gaattaacga atcaaactga ttttttgttg
     1141 attcgaaagc aacaagagca agaaaaaaat taatggctac ttatagccaa ttgattgatg
     1201 aatgggaaca attcaaggaa tctaaaattc cagaacgtct ctaaaagcct ttatttgtaa
     1261 agagcataag gaaacgtggg aacacttttt aaaaaaagtg ttccaatagg ctgtgcctat
     1321 tacgtttctc aaaaataaat gtgggaacaa aatatttaaa aataggatag tgaaaggata
     1381 gtgaaggata gtaaaaggag ggtagtagga tagcaaaaag gataggctcc ttttcgctat
     1441 cctttttaaa ttggaggaat taatatggaa gtaagaataa gaaatgtgga tgagaaaatc
     1501 gtaagagaaa ttgatcgaag atgtgacgaa
//
LOCUS       DACGLI010000155         1458 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.167, whole genome shotgun sequence.
ACCESSION   DACGLI010000155 DACGLI010000000
VERSION     DACGLI010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.167"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..354
                     /locus_tag="IXT22_002955"
     CDS             <1..354
                     /locus_tag="IXT22_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4864250.1"
                     /translation="TQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVD
                     QEMYKQAQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISI
                     LKELEEHENWYAEVE"
     gene            355..903
                     /locus_tag="IXT22_002956"
     CDS             355..903
                     /locus_tag="IXT22_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864251.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            1163..1458
                     /locus_tag="IXT22_002957"
                     /pseudo
     CDS             1163..1458
                     /locus_tag="IXT22_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          575 a          182 c          311 g          390 t
ORIGIN      
        1 acccaagtaa aatcgatgag aaatgcgatg caatatcttg agtatatgga cttttttgtg
       61 aaagaatttg atacaaattt atatgttgct ggtgttattc ctttcatgtt ggaaagcggt
      121 gacgcagtag atcaggaaat gtataaacaa gcccaagaga tttatgggga acatttgatt
      181 aaaaatgttg tactcaaaaa tgcgcgctta aaacgatacg acggatcagg tattacgatg
      241 gagaagacaa agaaaggtct cttaaaacaa tgggatcgca aaagccacga attatttatc
      301 agtattttga aagaattgga agaacacgag aattggtatg cggaggtgga gtaattggct
      361 gacatcaaag gacttgatat ttttgggaac aacaaaggac tcgccaaaat aaaaaaagaa
      421 gcagaagcaa agaaaaagca gcaagcaatt acaccatctg aaaataagca attagaagtg
      481 caccaagttc aagaaataaa aacttcctcc aatgttgaaa gacagagtag aggaagaaca
      541 aaaaaagttg gcgcaccaat cagaaagttt gataaggttt attccaccaa gcatccttta
      601 aaactgtcga ctttgttaaa tgcgacttcc agagttttag tagaaaagta tgagactaat
      661 atgacaagag atgaattgct tagaaaagct ttagatgagt atattaaaca gaatcttacg
      721 caagaagata agcaagattt gtttaatgac gtggtgaaag aactagactt gttcagagaa
      781 aaatatccaa ttgttccaga attagatgat cgtggagaaa taataagaac taccagtcag
      841 ataaaacaag ataccgaaga ctcactgcgc aaagggtggg gaatgaataa taaagttaga
      901 taataatcaa agaagaacta agtaactacc tttaaacggt agttacttag ttcttctttg
      961 atttgcatga aatagagggg atttattttt ctggttacgt gattaaaaaa tccaaaaaat
     1021 gagcatagga acggttatga ttttagggtg tgttttaatg agatattgtg atttcattaa
     1081 caagtgtatg ataatctgtt gttgagttag taaataagta atagagctaa ctctaaaata
     1141 aaactattag gaggagatgt aggtgaaaaa gtttaaaaag aaaatatatt taggattggt
     1201 tgttggggtg agtatgtttg ggttcatggc tcatactaaa caagtaactg cagatactaa
     1261 ccaaaaagaa aggattatga gccaattaga tgactctcaa ataagtatgt acccaatgag
     1321 ctaattgtca gtttaaaggc tacacaaaga atttcaacag agaaaaataa accgcaaaat
     1381 ttattgggtg taaaagttat ggtggaaaaa gatttgactc ttaggacaaa tgaaagcgat
     1441 tgtaataagc gagatcaa
//
LOCUS       DACGLI010000156         1424 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.168, whole genome shotgun sequence.
ACCESSION   DACGLI010000156 DACGLI010000000
VERSION     DACGLI010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.168"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(150..1337)
                     /locus_tag="IXT22_002958"
     CDS             complement(150..1337)
                     /locus_tag="IXT22_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAQ4864252.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACGLI010000157         1422 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.169, whole genome shotgun sequence.
ACCESSION   DACGLI010000157 DACGLI010000000
VERSION     DACGLI010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.169"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            6..980
                     /locus_tag="IXT22_002959"
     CDS             6..980
                     /locus_tag="IXT22_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4864253.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          497 a          184 c          236 g          505 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta ta
//
LOCUS       DACGLI010000158         1406 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.171, whole genome shotgun sequence.
ACCESSION   DACGLI010000158 DACGLI010000000
VERSION     DACGLI010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.171"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            295..1343
                     /locus_tag="IXT22_002960"
                     /pseudo
     CDS             295..1343
                     /locus_tag="IXT22_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180785.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
BASE COUNT          553 a          168 c          269 g          416 t
ORIGIN      
        1 cttcgttgac gtcttgacat gaaaaatcct ccagtgtgtt ttttattatt ctacacacct
       61 tattttttct gtctagtcta gtgtagccga ttcaaattga tgaagcagat cccaaagggc
      121 tgcttcatca attttttcgt aagtgtccgt acacttactg tgcttgctca tatattaatc
      181 gatcatatac taatcgtgta agaacaactt taagcataat acttatattg ttataccata
      241 gtttggaaaa ataaaaaatt atatttcatc aacgtttcat aaaaggtgtg tagaatgtta
      301 ttgaaagtag ctataaaatg ctattgtgta aaaaataaag gaggaataat ttatgaaaaa
      361 atagtaccaa gaggagcatg cctattactt gcattatgtt tgagcttaag cgcagttggg
      421 tgtcaaaaaa gtaatgaaaa caataaaata aaagaaggac aatccataag ttctgaagag
      481 gaaggcatgt caattaatgc aaatggcaaa aatgaaactt ttaagccatc agattataca
      541 ttggaggcaa agaaagaata tgtttatgaa tatttagggc ttaaatttaa actctcagac
      601 aaatttagaa attatatagc tgataaaaag atagcgatgt tagatgatca aagtcctata
      661 gataaagaac taaagtatgc tattttgaca tttgagaaaa tgacagaaga acaaaagaat
      721 gcagttatag aaaagatggg cgatggatat aaaaattggc aaaatgagct tgaaagaatt
      781 gggactattg gtatatttga aaaaaataca tcagaagaaa aaaatctaaa attataaaat
      841 gtgatactca tactaaaata ggagtttcaa gtgatggaaa atacgattgc tatttaagca
      901 caaatagcgg agctgaaagt aatcttctgg atgaattaaa aagaactgag attcaaatta
      961 tagataaaaa agaacgtcct aaaaatggtt ttgtgctatc agaaaaaact gatttagaaa
     1021 atacagaagc atttaacaaa gaatcggtta aagatttacg taaactacca acaaaggaca
     1081 taaatggcaa ggattttaca agtaaagatt ttgagaagta tgatcttact atggtaaatg
     1141 tatttgcaac ttggtgtaca gcttgtgtaa aggaaattcc tgatttggtt gaggttcaga
     1201 atgaaatgaa aagcaagggt gtaaatatcg ttggagttgt tacagatcct gttgatgata
     1261 acggtgaaaa caaggaagca attgaaaagt caaagttaat acatgaaaag acaaaggctt
     1321 catatccttt cttaatgcca gatggaatgg caacactttt tttgacaaaa attataaggt
     1381 gttgtgaatg ctgcggtgtt atggct
//
LOCUS       DACGLI010000159         1399 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.172, whole genome shotgun sequence.
ACCESSION   DACGLI010000159 DACGLI010000000
VERSION     DACGLI010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.172"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            149..1318
                     /locus_tag="IXT22_002961"
     CDS             149..1318
                     /locus_tag="IXT22_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864254.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          508 a          226 c          241 g          424 t
ORIGIN      
        1 atccatagtt aatttatcat aatatcccat attttaaaat aaaagatagc gtaaaatatt
       61 ttgtgtaaat agaaatttag ggtagaaaaa aaagtccatt ctgtaaaatt aaagttacca
      121 cacagaaatt ttataggagg actttctcat gactaaattt actatagaaa ttatgcaaac
      181 actactcaat aaaggggatt tagatgaatt atttcaggat catttagagc gagcgattaa
      241 ttcacttcta caagcagagc taactgcttt tttagattac gaaaaatatg atcgaaatgg
      301 attcaattca ggaaattccc gtaacgggaa ttattcacgt acatttaaaa cagaatatgg
      361 cgagttgaat ttaactattc ctagagatcg gaatggcgaa ttttctcaac aaacactacc
      421 agcatataag cgaaccaatg attcattaga aacgaccatt atccaattat ttcaaaaagg
      481 cattactatg gctgaaatct ccaaattaat tgaaaaaatg tatggtcacc actatacgcc
      541 acaaacaatc tccaacatga gtaaattggt ggctgaagat gttttagctt ttaaagaaag
      601 aacgttagaa gccaattatt ccgttatatt tatggatgcg acgcatatcc ctgtgaagcg
      661 acagactgtt tcgaaggaag cagtgtatat tacgattggt attcgtttgg atggaaccaa
      721 agaagttctt gggtttacta ttgccccaac tgagtctgct tatatttgga aagaagttct
      781 tcaagatctt agaaaacgtg ggttagaaga agttttatta gtagtgacag acggattaag
      841 ctgtattgaa gaaagtatcc atagtgtgta tccgaatgcc caatttcaac aatgttgtgt
      901 gcatgtatct agaaatatcg ctcataaagt tcgtgttcga ggtcgaaaag aaatttgtga
      961 ggatttcaaa ttggtttacc aagcgaattc aaaagaagag gcattggatc acatcgactt
     1021 tatgactagg aaatggaaaa agcagtatcc aagagtcgtc aatttactct tgaatcctgc
     1081 cctattaacc ttttataatt tccctcacgc catcagacga acaatttatt cgacgaacct
     1141 gattgaaggc tttaataagc agctaaaacg atatactcga agaaaagaac aattccctaa
     1201 tgaagaatct ctagagagat tcttcatttc tcaatttaat caatataacc aaaaattttt
     1261 aggtagaatt cacaagggat ttaaagaaat tcaggataca ttagagtcga tgatttaact
     1321 gtaattaaca gaatggattt tccatttaca tataattctt gacgctacca taatctaaat
     1381 aaccatcata ttcatctac
//
LOCUS       DACGLI010000160         1359 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.173, whole genome shotgun sequence.
ACCESSION   DACGLI010000160 DACGLI010000000
VERSION     DACGLI010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.173"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..484
                     /locus_tag="IXT22_002962"
     CDS             <1..484
                     /locus_tag="IXT22_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4864255.1"
                     /translation="KEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQ
                     QVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSN
                     NQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK
                     "
     gene            complement(691..1092)
                     /locus_tag="IXT22_002963"
     CDS             complement(691..1092)
                     /locus_tag="IXT22_002963"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864256.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(1213..1296)
                     /locus_tag="IXT22_002964"
                     /pseudo
     CDS             complement(1213..1296)
                     /locus_tag="IXT22_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
BASE COUNT          445 a          254 c          260 g          400 t
ORIGIN      
        1 aaaggaagcg atcgatcaaa tcaagacggc tgtcttgtat cctcataacg gattaccgat
       61 tttattgatg ggtgtaagcg gttcaggaaa aacctttttg gcagaaaaaa tttatgaata
      121 cgccaaggaa caacaggtga tagaatcaaa tgctccattt atcgcctata attgtgctca
      181 atactttaat ttctcgatta acaagatcgt agaaaattta acgatccttg atgcaatgaa
      241 ggttttgaga ttggtacaaa aggccgtcaa agaactcgaa aaactaatgg ggatcgaatt
      301 ttcaaacaat caattgttct tgctttacat gcactgctgc tcaatgatcg aacgtatttt
      361 acgcaaagaa agtgtagatg aacaagcaga tatcaaagaa tatattcaaa aagagggaca
      421 taattatgaa atatcaaaat acccggctta caaaacgaag tttgaaagta ctgtaataaa
      481 gtaagattta aataagcata aacaaggtaa gaaccatagg ggctgtgtca agtccaaaat
      541 cttgtgtaaa aaggaaatct caaagtacga tgttttgcct tgttgagcct agctacggtc
      601 caatatgctg gtaagaagtg tcaagagcaa aaagcgaagc gtctcttgat acttctcacc
      661 agtatattat actattggcg gcttaatgtg ctaaatctcg ttacgatcaa attcaagata
      721 ttttctaggt gcagaagtcc attcgtcatc cttttccatc aataaagcac cgatgatacg
      781 aataacagaa tcacaatttg ggaaaattcg gacaacacgt tcacgacggc gtacttcttc
      841 atttagtctt tcaagaacat tcgttgttct caatcgttga cggatatttt ctggtaaaac
      901 cattacttgc atggcatctt cgaagccctc atccaatatt ttacaggcag ttgcgacttt
      961 cttgtcttcc ccatatttat ccataataag ttgtttacgt tctccagcca gctcgatgct
     1021 tgccgttttg aagatggctt taaagtcttc tttgatatcg cttgagattt tcttggagaa
     1081 tttgtcggaa atgttgcgaa ggagatgtgc ttggcatctc tgctagctcg cacaaagaag
     1141 gtattctttc acagcttttg tgagccctat atgcgcatcc gagatgacca tctttactcc
     1201 tgaaagaccg cgttctttca atccgagagt gtaaaatatt ttgtgtaaat agaaaaaagg
     1261 aagtcccttc agtagaatag agttaccaca acacattcac agaaaagagg acttccatat
     1321 gaacgatttt actacagaaa ttctaaagac tctagcgaa
//
LOCUS       DACGLI010000161         1356 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.174, whole genome shotgun sequence.
ACCESSION   DACGLI010000161 DACGLI010000000
VERSION     DACGLI010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.174"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            21..1322
                     /locus_tag="IXT22_002965"
     CDS             21..1322
                     /locus_tag="IXT22_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4864257.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          439 a          270 c          252 g          395 t
ORIGIN      
        1 caatcaaagg agcgttctgt atgcctgatc ttcatcatat caaactacta cttggaatca
       61 aagataaaaa cattttcatc acaaatgtgg aatcgaagag cattaagaat atcaagagtc
      121 ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg tcctttgtgt aaacagatga
      181 atcatgaagg catgatcgtt aagaacggaa agaaaaaatc gctcattcaa cttaataaat
      241 gtgcgaacca actgacttat cttgctttag cgaaacaacg ctaccactgt cgtggctgcc
      301 acacctattt tacggcgaat acctacattg tcgatagaaa ctgctttatc gctaaacaag
      361 tgcgctataa aattttagaa gagctaactg aaaaacaagc aatgacgaca attgctaagc
      421 attgcggcgt ttcttggtcg accgtttctc ggacactcgc ttctctgatc cccatgacaa
      481 aagtaaaaag aaattggtta ccgcgttgtt tattaatgga tgaatttcgt tcactgaaaa
      541 atcaagtcgg tccctactcc ttttcttgta tggatggcga tactggaaaa ttactggata
      601 ttcttccttc acggaagaaa aaggctctcg tttcttattt tatgcaattt gaacgacgcg
      661 cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt ttcttatgcc tctctgataa
      721 aggaatgttt tccaaaggca aaactcgttg tggatcgttt tcacattgtc aaacatctca
      781 ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag ctttgatcga aacgatccaa
      841 cacaagccaa atattatcga caattaaagg cgttgtctcg gcttctgatc aaacgacagg
      901 acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt tggttgggcg tatctcaccg
      961 aaagtgaagt ggtggatcgt ctgctttcga tctctgacga attacgaatc gcctattttt
     1021 actatcaaga aattcttcaa gcgtttcacg acaaagaggc ggacactttc tttaaacttg
     1081 taagaacgat gcccaattcc gttccaaaag aactgcattc tataaaaaaa gcttttataa
     1141 actatgaatc cggcattcgt ttagccctcg aattgcctta ttcaaatgcc aaaatagaaa
     1201 atctgcatac ccacatcaaa gcattgaaac gagtcgctta tggctttcga agctttcgga
     1261 aaatgaagac cagaattttc ttactaaata atctgattac ctatgaatca aaaaacatct
     1321 aaagtagaaa aggaattcta ccttagatgt tcttat
//
LOCUS       DACGLI010000162         1354 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.175, whole genome shotgun sequence.
ACCESSION   DACGLI010000162 DACGLI010000000
VERSION     DACGLI010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.175"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            82..>1354
                     /locus_tag="IXT22_002966"
     CDS             82..>1354
                     /locus_tag="IXT22_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAQ4864258.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLI"
BASE COUNT          460 a          261 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atca
//
LOCUS       DACGLI010000163         1337 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.177, whole genome shotgun sequence.
ACCESSION   DACGLI010000163 DACGLI010000000
VERSION     DACGLI010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.177"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..252)
                     /locus_tag="IXT22_002967"
     CDS             complement(<1..252)
                     /locus_tag="IXT22_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /protein_id="HAQ4864259.1"
                     /translation="MLKQKELIANVKNLTESDERITACMMYGSFTKGEGDQYSDIEFY
                     IFLKDSITSNFDSSNWLFDVAPYLMLYKNEYGTEVVIFDN"
     gene            complement(306..>1337)
                     /locus_tag="IXT22_002968"
     CDS             complement(306..>1337)
                     /locus_tag="IXT22_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4864260.1"
                     /translation="ARNVVQNYLKRKKGFILVSHDRSLLDQCVDHILSINKTNIEIQK
                     GNFTSWWENKTLQDNFELAENKKLLKEIGRLSYAAKRSSNWSNKVEKSKYGTTNSGSK
                     LDKGYVGHKAAKAMKRAKNIESRHQEAVLQKSELLHNIEQYDDLKISPLEFHKECLIE
                     ANDLSLSYGDKEVCSNLNFRVNIGDRVAIIGKNGSGKSSILKLINGDDIKFTGNFMLA
                     SGLKISYISQDTSYLKGNLSEFAYNNKIDETLFKTILRKLDFNREQFDKNMVDFSAGQ
                     KKKVLIAKSLCESAHLYIWDEPLNYIDIFSRIQIEKMILEYCPTLLFVEHDDAFCNNI
                     CTKNINLGL"
BASE COUNT          413 a          257 c          170 g          497 t
ORIGIN      
        1 attatcaaaa ataactacct ctgttccgta ctcattttta taaagcatca agtacggagc
       61 tacgtcaaac aaccagttgg atgaatcaaa gttcgaggtt atactatctt tcaaaaatat
      121 atagaactct atatcagagt attggtcacc ttctcctttg gtaaacgatc catacatcat
      181 acaagctgta attcgttcat ctgactcagt aagattctta acgtttgcaa ttaattcttt
      241 ttgttttaac atttcttcac cctttcatgt aaatatcttt tagttattgt ggcaactcaa
      301 aatctctaca aacctaaatt aatatttttc gtacaaatgt tattgcaaaa agcatcatca
      361 tgctccacaa acaatagtgt aggacaatat tccaaaatca ttttttcaat ttggatacgt
      421 gaaaaaatat caatatagtt caatggctca tcccatatat acaaatgtgc actttcacaa
      481 aggcttttag caattagtac tttctttttc tgaccagcac taaaatccac catgttctta
      541 tcaaactgct ctctattaaa atccagttta cgaagaatcg ttttaaatag agtttcatcg
      601 atcttattat tataggcaaa ttcagataga ttacctttta aatatgaagt atcttgcgaa
      661 atataagaaa tttttagtcc acttgctagc ataaaatttc cggtaaattt aatatcatct
      721 ccattaatca attttaggat actagactta ccactcccat tttttccgat aatggcaact
      781 ctatcaccaa tattgactct gaaattaaga ttactgcata cttctttatc tccataagac
      841 aatgataaat cattcgcttc tattaagcac tctttgtgaa attcaagtgg tgaaattttt
      901 aagtcatcat attgttcaat gttgtggagc agttctgatt tttgtaaaac ggcttcctga
      961 tgtcttgact caatattttt ggcacgtttc atcgcttttg cagccttatg tccaacataa
     1021 cccttatcca gttttgaacc agaatttgtt gttccatatt tacttttttc tactttattt
     1081 gaccagtttg aactacgttt tgctgcataa gacaaccttc ctatttcttt aaggagtttc
     1141 ttgttttctg ccagttcaaa attatcttgt aacgttttgt tctcccacca agaagtaaaa
     1201 tttccctttt ggatttcgat attcgtttta ttgatagata gtatatggtc aacacattga
     1261 tcaagtaagc ttctatcatg agataccaaa ataaacccct tcttgcgttt caaatagttt
     1321 tgcactacat tacgtgc
//
LOCUS       DACGLI010000164         1312 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.178, whole genome shotgun sequence.
ACCESSION   DACGLI010000164 DACGLI010000000
VERSION     DACGLI010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.178"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(156..1297)
                     /locus_tag="IXT22_002969"
     CDS             complement(join(156..1069,1069..1297))
                     /locus_tag="IXT22_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4864261.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          323 a          263 c          278 g          448 t
ORIGIN      
        1 gacacgattt gtgagaattt tttcgagatt ccagcgggtg agtatctcat cgtttcgacc
       61 agcggtcaaa ccaaaaccgt ttgaccgctg atcgaagcga tgaagttgaa accctgtgga
      121 aatctcgcca aaaaaatgta agtggtagct aggaactaag cttgcaatgc caactcctcc
      181 atctgatttg gtgttaaata gttgatacta ctatggattc gcttgcgatt gtaaaatcct
      241 tcaatgtatt gaaataacgc taaataagca gcttcaaagt tttcatacgc ttttgatgga
      301 tagacttctt cttttttgag tgaggcgtga aacgattcga taccggcatt atcgtaggga
      361 cagcccttac gactgaagga gtgccgaatg ttcaattcat tcagctttgc ctcataggct
      421 tcgctagtgt actgagaacc caaatctgag tggatgatca agttctcgga gggtgtttgg
      481 tttaagagcg cattgtcaag ggtttcgata accaattctt tcgtcatctg cttgccaaac
      541 ttccaaccga tgactttctt tgtgtggagg tcttgaatag tggagaggta ggtccagcca
      601 tcttttaggg tatgaatata ggtaatatct gtcacccatt tttgattgat cgacgtagtg
      661 gtaaaatctt ggtttaacag gtttttacgt ccttcacttt taactttcgc ttgtttgcca
      721 ggcttgtact tcttgagggt gactgaacgc aagcctaatt ttctcatcag tatttgtact
      781 ttctttaagg acaaggtctc gccacggcca acaagaatct tatgaatttt aggcgcacca
      841 tagataccct tgttttcaaa gtagattcct gaaatcaagc ggtttaagcg tttgttttct
      901 gattggcgct tggaaggttt ctttttcttc cagtcatagt agctggattt cggtgcttcc
      961 aaaacggtac acatttgttt tacgtcatga tcatgaacat ttgattgaat aaattcgaag
     1021 acatcactca tttttacttt tgagcgaata tggttaaagc cttttttagg atagtgtttt
     1081 cctcctgcat gcgggccatt tcctttttca tcgctaggat ttctgcctca gtcatgccgg
     1141 ttgctacatt ctttgtatga agcttcttcc aacgataaat cgtttgtgta gcgataccat
     1201 attgcgctgc cagttcttcg accgattggc cagactggtt taaatctaag atcatcttct
     1261 taaagtcttc atcaaatttt ttcttggctt ttgccatcgt ggacacgtcc tt
//
LOCUS       DACGLI010000165         1295 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.179, whole genome shotgun sequence.
ACCESSION   DACGLI010000165 DACGLI010000000
VERSION     DACGLI010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.179"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            143..400
                     /locus_tag="IXT22_002970"
     CDS             143..400
                     /locus_tag="IXT22_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864262.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1045)
                     /locus_tag="IXT22_002971"
     CDS             complement(632..1045)
                     /locus_tag="IXT22_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAQ4864263.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          488 a          165 c          162 g          480 t
ORIGIN      
        1 ttttctgtcc acgttcatat tactccaaag ttttcctcat tccaaaagaa aagcacagaa
       61 tacacaaaga agcgttttta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt gttactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacatc ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc taaaatataa
     1201 gctatttgtt tacttctgta gaatatatac tttgttgtta gataagttgc acatgtttat
     1261 agaatctaaa taataaattt ttatgtaccg cccct
//
LOCUS       DACGLI010000166         1263 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.180, whole genome shotgun sequence.
ACCESSION   DACGLI010000166 DACGLI010000000
VERSION     DACGLI010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.180"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            70..1239
                     /locus_tag="IXT22_002972"
     CDS             70..1239
                     /locus_tag="IXT22_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864264.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          458 a          190 c          207 g          408 t
ORIGIN      
        1 agaaaaaaag aaagtccatt ctgtaaaatt aaagttacca caaccgaaat tttataggag
       61 gactttctca tgcccaattt tactacagaa attatggaaa cactaatcaa taaaggtgat
      121 ttagatgaat tatttcgatg tcatttagaa ttagctgtta attcattatt gcaggctgaa
      181 ttaacagctt ttcttgatta tgaaaaatat gatcgtgctg ggttcaattc aggtaattcc
      241 cgtaatggga attattcacg ttcattcaga acagagtatg gagaattaaa tttggtaatt
      301 cctagagata gaaatggtaa gttttctcaa caaactttac ctgcttataa aagaaccaat
      361 gactctttag aaaccactat tattcagcta tttcaaaaag gaattactat gtctgaaatc
      421 tctgaattga ttgaaaaaat gtacgggcat cactatacgc cacaaaccat ttcaaatatg
      481 actaaaatag tttctgaaga tattattgcc tttaaagaaa ggtccttaga atccagatac
      541 tctgtcattt ttatggatgc tactcacatt cctttaaaaa gacaaactgt ttcaaaagaa
      601 gcagtttata ttgtaattgg cattcgatta gatggaacca aagaggttct tgggtttagt
      661 cttgctccaa ctgaatctgc ttatgtttgg aaagagattc ttcaagacct aaaagaccgt
      721 ggtttaaaag aggttttatt agtcgtaact gatggtttaa gtggcattaa cgatagtatt
      781 catagtgttt atccaaatgc tcaatttcaa caatgttgtg tccatatatc tagaaatatc
      841 gctcataagg ttcgtgttag tgatcgacaa gaaatctgta gcgatttcaa attagtttat
      901 caagcaagtt caaaagaaga agcaaataat caaataaggt ttatgataga taaatggaaa
      961 aagcagtatc cacgagtggt taaattgctc atgaatcctg ctatattaac cttttataat
     1021 ttccctccgt caatcagaag aactatttat tcaactaatt tgattgaagg ttttaacaaa
     1081 caattaaaga aatataccaa aagaaaagag caatttccta atgaagaatc tctggagaga
     1141 tttctagtat ctcaattcaa caactataat caaaagtttc tatgccgagt tcataaaggt
     1201 tttaaagaaa tacatgatac attagaatca atgttttaac ttgatcaaca gaatgggctt
     1261 ttc
//
LOCUS       DACGLI010000167         1258 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.181, whole genome shotgun sequence.
ACCESSION   DACGLI010000167 DACGLI010000000
VERSION     DACGLI010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.181"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            26..>1258
                     /locus_tag="IXT22_002973"
     CDS             26..>1258
                     /locus_tag="IXT22_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4864265.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFR"
BASE COUNT          387 a          253 c          248 g          370 t
ORIGIN      
        1 ctaccaattc ataggaggat tcaagatgtc tcatactcag cttatcaaag ataccctaaa
       61 tattctagac ctaaatatct atttcgagga aaattgttta actaaagaaa aatacaaagg
      121 gcaaatttgc ttgatttaca aaggaactct tctgtacaag ccagaagagt gttcccattg
      181 tctttgtgtc gtcccctcta ggatcattcg ttgggggacg acaaccgttc ggttgttact
      241 gaatgatgtg tctgagtatc gcacttatct ggagctgaag aaacaacgat ttaaatgtaa
      301 gtcttgccaa agaacattcg tagcggatac ctctgttgct gaaaaacact gtttcattag
      361 tcaaaaagtt cgttggtctg tcattgctcg cttaaaagag aatacttcca tgacggaaat
      421 cgctcgtcag aaaaatattt ccacttcttc ggtctatcgt gtcatgaagc gattctaccg
      481 cccattgaat cctttcaaac agactttgcc aaaggtctta tgctttgatg aattcaaatc
      541 ggttcgaagt gttgccagtg caatgagttt tatcatgatg gacggacaaa gccatgcatt
      601 attggatatt gtcgaaaatc gacgcttgcc ttatttagaa cgctattttt ctcggttttc
      661 attagcgact cgtgaagccg ttcaattgat tgttattgat atgtatgcgc cttatgtttc
      721 gttggtgaaa aagcttttcc cgaatgctca gttgatcatc gatcgtttcc acatcgtcca
      781 acatattggc agaactttct tgaatcatcg agtgaaagaa accacggtac gacttaaagg
      841 aaattcccac tctcaacgag ggttagggaa aaaattgaag cgctattgga aactcctaca
      901 aaaagaagaa gcaaagttaa actatgaaaa acgggtttgg cgtgccagtt ttaaagatta
      961 tttgactgaa agtgagattg ccgatcgact gttagctgct tgtcccaact tacgccaagg
     1021 ctatcagtta taccaagaca ttctttatgc ggtaaagaaa agagatcagt cactatttga
     1081 ggattgttta actagagaca ttagcggtct gccagaaacc tatacaacca ctttacgaac
     1141 gtttaaaaag tttctgccac agatccaaaa tgcgcttcac tacagctatt caaacggacc
     1201 attggaatgc ttaaacaacc acatcaaagt attaaaacgc aatgcgtacg gctttcgc
//
LOCUS       DACGLI010000168         1235 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.182, whole genome shotgun sequence.
ACCESSION   DACGLI010000168 DACGLI010000000
VERSION     DACGLI010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.182"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..>1235
                     /locus_tag="IXT22_002974"
     CDS             <1..>1235
                     /locus_tag="IXT22_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4864266.1"
                     /translation="KLCEQVPEKEQKQSVKNEPVSKEQMQSKETKTKQKGYQKRTAEE
                     IKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQFPGATACL
                     GRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGFVREIEATPEDKKRIESGQIEV
                     IKKTYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANNIGI
                     QIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIHELAHARMH
                     KFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYIAAWTKNGQTLDDKEAAERGKI
                     MNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWI
                     DKKDGKVMEEDTGRTLHLK"
BASE COUNT          482 a          205 c          270 g          278 t
ORIGIN      
        1 aaattgtgcg aacaagtacc tgagaaggaa caaaaacaat cggtcaaaaa tgaacctgtt
       61 tcgaaagaac aaatgcagtc gaaagaaaca aaaacaaaac aaaagggcta tcaaaaacga
      121 acggcagaag agattaaaca agaagttaaa tccctttcgc aacaggcact ggatgcggtg
      181 aaaaagcata ctcattctcc tgaagacgtc aaagaacttt tgaactttat gtctcgtttt
      241 ccagaacgat cctttagaaa tcaattattg attgaggaac aatttccagg tgcaacggct
      301 tgtttaggtc gtgccgcgtt gaaaaaagaa ggaatctata tcaaaaaagg ggaacaaggg
      361 aacaagatct ttgtcagaaa aacggtcaaa ggattttatg agaaaggacg tggctttgtt
      421 cgagaaatag aagctacacc agaagataaa aaacgaatcg aaagtggtca aatcgaagtg
      481 atcaaaaaaa cttactacac gattgaaaaa gtgtttgata tcacacaaac acagttaaaa
      541 cctgaagact atccgaaaat ctttccgaac cgtgtctttg attttcaatt ggataaaaaa
      601 ggacagtcag aacttcaagc tgggattcaa gcggtagcca acaatattgg aatacaaatt
      661 cgagatatga cagaaagtga agtctatcaa agagaattag gacaagcacg tggggcgtat
      721 gttcgtaacg aatttactgg cgaagaagaa atcgtcatga atactcgaaa tactcctacg
      781 cagcatttag ctacaagtat tcatgaatta gcccatgcaa gaatgcacaa attttcagaa
      841 ttagataccg caactaaaga attgcaggca gaaatgactt cttatattgt gtgcaaacat
      901 tttggaatgg acacgttgga gaaagctatt ccttatattg cagcatggac gaagaatggt
      961 cagacgttgg atgataagga agctgcggaa cgtgggaaaa tcatgaatga tgtcagccgt
     1021 gtcgcaaatg aattcattca aaccatttct aatgaaatca atcaatacag agaaagagaa
     1081 ccagagatcc aaccagcaga agtgaagcag gagcataaaa atactgtaga aacggcagaa
     1141 caaaagaata ttgttcctgt tggttcactt tggatcgaca agaaagacgg gaaagtaatg
     1201 gaagaagata cgggtcgaac gttacatttg aagga
//
LOCUS       DACGLI010000169         1198 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.183, whole genome shotgun sequence.
ACCESSION   DACGLI010000169 DACGLI010000000
VERSION     DACGLI010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.183"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..449)
                     /locus_tag="IXT22_002975"
     CDS             complement(<1..449)
                     /locus_tag="IXT22_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864267.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKS"
     gene            557..841
                     /locus_tag="IXT22_002976"
                     /pseudo
     CDS             557..841
                     /locus_tag="IXT22_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
BASE COUNT          372 a          179 c          216 g          431 t
ORIGIN      
        1 gatttaaagg catttacttc ttcagtcaga actttagtca tgttggacat ggtttgtgga
       61 gtatagtgat gaccgtacat tttttcgatc aaatcagcaa tttcagacat cgtaacacct
      121 ttttcgaata aatggataat agtggtttcc aatgtatcgt ttgttctttt gtaggctggt
      181 aaagtttgtt gtttaaactc accattacga tctctaggta tttccaatgt taattcacca
      241 tattcggttt tgattgatcg aaagtaagaa ccgtttctcg aattacctga attaaaacca
      301 gtgcgatcat atttttcgta atctaaaaaa gccgttaatt cagtccgtag tagtgtgttt
      361 atcgcttttt ctaagtgcga acggaataat tcatttaaat cgcctttagt gactagagtt
      421 tgcacaattt ctgtagtaaa atcattcata gggaagtcct cttttctgtg aattggttgt
      481 cgttaacttt attctacaga agggacttcc ttttttgtat ggattttttc atttacacaa
      541 aatattttat actctcattt taatacaaga tgatttacac catacgcatc ggttatggtt
      601 aatgaataaa attaatctgt attttgggca ttcttatgtt tttgcttttt atgattacag
      661 gacaaatata actgaagtag atttggttat ttctaattac tacatcgaca ctggaaaaac
      721 gccattactg ttaatgaaaa atatacctac cgaaagaaac tggcgtttgt tcgagaaaac
      781 gatttatcaa ttgaaaaaag aaaaagaggt tgtgaaatca gcgttttgtc ctgagtatta
      841 gagaaacaaa cggaaaaata gtttttcata ttttgccgtt tttgagctaa taccgaggga
      901 cagctgattg aacaccattt attgagagat tgtgaaaaaa ctgtcctgca tcaagtaata
      961 agaacagcca agtaaaaaca gcttctcatg tttgttgaat attgtgactt gtgaccgagg
     1021 agttggcaag agaacaccgt ttattcggaa aaagggactg tgacactaca tgtcacagtc
     1081 cctttttgat tgaattatct catttgtttt ctaatttttt ctttatttga gaaaatagtt
     1141 gaactggata aaaagtactg gacgtgtcaa aattattttg gatcaaatta gatctatt
//
LOCUS       DACGLI010000170         1159 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.184, whole genome shotgun sequence.
ACCESSION   DACGLI010000170 DACGLI010000000
VERSION     DACGLI010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.184"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            296..>1159
                     /locus_tag="IXT22_002977"
     CDS             296..>1159
                     /locus_tag="IXT22_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAQ4864268.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHKKLNL"
BASE COUNT          445 a          139 c          229 g          346 t
ORIGIN      
        1 tacaaaaaag atgttggtga agttcaccaa catcaaaaag tatagagcca aaataaaaaa
       61 agcacctgaa aaggtgtctt tttttgatgg ttttgaactt gttctttctt atcttgatat
      121 atatagaaat aacgtcattt ttattttagt tgctgaaagg tgcgttgaag tgttggtatg
      181 tatgtgtttt aaagtattga aaacccttaa aattggttgc acagaaaaac cccatctgtt
      241 aaagttataa gtgaccaaac aaataactaa atagatgggg gtttctttta atattatgtg
      301 tcctaatagt agcatttatt cagatgaaaa atcaagggtt ttagtggaca agacaaaaag
      361 tggaaaagtg agaccatgga gagaaaagaa aatcgctaat gttgattact ttgaacttct
      421 gcatattctt gaatttaaaa aggctgaaag agtaaaagat tgtgctgaaa tattagagta
      481 taaacaaaat cgtgaaacag gcgaaagaaa gttgtatcga gtgtggtttt gtaaatccag
      541 gctttgtcca atgtgcaact ggaggagagc aatgaaacat ggcattcagt cacaaaaggt
      601 tgttgctgaa gttattaaac aaaagccaac agttcgttgg ttgtttctca cattaacagt
      661 taaaaatgtt tatgatggcg aagaattaaa taagagtttg tcagatatgg ctcaaggatt
      721 tcgccgaatg atgcaatata aaaaaattaa taaaaatctt gttggtttta tgcgtgcaac
      781 ggaagtgaca ataaataata aagataattc ttataatcag cacatgcatg tattggtatg
      841 tgtggaacca acttatttta agaatacaga aaactacgtg aatcaaaaac aatggattca
      901 attttggaaa aaggcaatga aattagacta tgatccaaat gtaaaagttc aaatgattcg
      961 accgaaaaat aaatataaat cggatataca atcggcaatt gacgaaactg caaaatatcc
     1021 tgtaaaggat acggatttta tgaccgatga tgaagaaaag aatttgaaac gtttgtctga
     1081 tttggaggaa ggtttacacc gtaaaaggtt aatctcctat ggtggtttgt taaaagaaat
     1141 acataaaaaa ttaaacctt
//
LOCUS       DACGLI010000171         1158 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.185, whole genome shotgun sequence.
ACCESSION   DACGLI010000171 DACGLI010000000
VERSION     DACGLI010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.185"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            116..1135
                     /locus_tag="IXT22_002978"
     CDS             116..1135
                     /locus_tag="IXT22_002978"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4864269.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT          407 a          183 c          260 g          308 t
ORIGIN      
        1 aagtaaaaac gataaaagaa gtaaacaaac acttaaaaac aatggaaatt agtcccaact
       61 ttaagaaatg tatactataa tggaaattat caattattta tttggaggaa tatccatgaa
      121 acaaaaaatc gcagttcttg gtcctggatc ttggggcact gctttagcac aaacattggc
      181 agaaaacggg catgatgtcc gtatttgggg aaatgtacct gaacagattg atgaaatcaa
      241 taagtatcat acaaatcagc attttttacc tgatttgacg atcccagaat cgattatcgg
      301 atataaagaa ttggcagaag cagtggataa cgcagatgct attttatttg ttgttccaac
      361 aaaagcgatt cgttcagtcg cacaggaact tattggtaaa atgaatacta agccaatcat
      421 tatacatgca agtaaaggac tagaacaaga tacgcataaa cgaatctcag aagttttggc
      481 tgaagaaatt ccagaagaaa aaagacaggc aattgttgta ttatctggtc ctagccatgc
      541 tgaggaagtg gcagtacatg atatcacaac aattacagct gcaagtattg atcaaaaagc
      601 agcagcctat gtacaaaaac tgttcatgaa tgattatttc aggatttata caaataatga
      661 tgtgattggc gtagaaactg gtgcagcact gaaaaatatc attgcaattg gtgccggcgc
      721 tatccatgga ttaggattcg gagatgatgc aaaagcagca atcatgactc gaggattggc
      781 agaaatcagc cgtcttggtg tcgcgatggg tgccaatcct ctgacattta tcggtttgag
      841 tggtgtgggg gacttgatcg ttacttgtac aagtgttcat tctcgcaatt ggcgtgccgg
      901 taacttgtta ggacagggac ataagctgga agaagttcta gaaaacatgg gaatggtcgt
      961 tgagggtgtg gcaacgacaa aagcagcagt agagctagct caacagctag gtgttgagat
     1021 gccaattact caaacaatct ataatgtttt gtataatgga gaagatatca aaaaagcagc
     1081 aaaagaaatc atgttacgtg acggaaaaat ggagaatgaa ttttctcttc gttaaataga
     1141 tgatcaatag ttaatcgt
//
LOCUS       DACGLI010000172         1123 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.186, whole genome shotgun sequence.
ACCESSION   DACGLI010000172 DACGLI010000000
VERSION     DACGLI010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.186"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(677..>1123)
                     /locus_tag="IXT22_002979"
     CDS             complement(677..>1123)
                     /locus_tag="IXT22_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4864270.1"
                     /translation="KIYGNIPYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNR
                     SLALFLMTEVDISILSKIPREYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKW
                     VNKEYIKLFSKNQFYQALKYARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          373 a          149 c          200 g          401 t
ORIGIN      
        1 ttgacggtat gtggttaaaa aagaaaaata gctaggagat ttttgagaga tgactggtaa
       61 atttaaaaat gatagaaatg gagagtatgt atgagtaata aacaattttt atggtcttct
      121 tttgcattta ttgttgttga tatttttttc cgatatttta ataacgatat gatatttaac
      181 tggcaaagaa ttataatcga ttactgtatt ttttgtataa tatatttttt agtgaaaaca
      241 tttctaaaat acgcaaaaaa ataaaattga agatgttatt aaatcgcgat tatttacgga
      301 gatttatata aataaaaacc ccctgacgaa gtcgaagggg gtttttattt tggtttgagg
      361 tttgcatacc taccgaaaag gtagggcagc aaatcgtcaa acaggtatca gctaattgca
      421 ccataagggt gcgctgatac tcggctcaaa agagccgaaa gagccgtctg caagacccct
      481 cggcgagccc acactttgct tgcaaagtat agtgggttat actttacatg gaagtaattg
      541 ccggaaatag tgaaaatgcc tcacatttgt gccacctaaa aaggagcgat ttacatatga
      601 gttatgcagt ttacgggcca agattgttta agcaaaataa gataagttaa gggatgcagt
      661 ttatgcaccc cttaacttat ctattaaata atttatagct attgaaaaga gacaagaatt
      721 gttcaaagct aatattgttt aaatcgtcaa ttcttgcata ttttaaggct tgataaaatt
      781 ggtttttgga aaatagtttt atgtattctt tgttaaccca tttcataaca aaattttcat
      841 attgttttct atctttgagt gatatttttg aagggtgtct ttttaataca attaacgagc
      901 tattaactct aggttttgga tgaaagtatt ctctagggat tttacttaat atggatatat
      961 caacttctgt cattaaaaat agtgctagtg aacgatttgt atttagcaac cttttagcaa
     1021 atccatattc cactattaaa taactttctg tagctgtgct ttcaaaaaca atttttcgaa
     1081 ttatatctgt acttatattg tagggtatat ttccatatat ctt
//
LOCUS       DACGLI010000173         1073 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.187, whole genome shotgun sequence.
ACCESSION   DACGLI010000173 DACGLI010000000
VERSION     DACGLI010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.187"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            2..>1073
                     /locus_tag="IXT22_002980"
     rRNA            2..>1073
                     /locus_tag="IXT22_002980"
                     /product="23S ribosomal RNA"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DACGLI010000174         1071 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.188, whole genome shotgun sequence.
ACCESSION   DACGLI010000174 DACGLI010000000
VERSION     DACGLI010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.188"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            82..>1071
                     /locus_tag="IXT22_002981"
     CDS             82..>1071
                     /locus_tag="IXT22_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HAQ4864271.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSL"
BASE COUNT          360 a          196 c          207 g          308 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct g
//
LOCUS       DACGLI010000175         1063 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.189, whole genome shotgun sequence.
ACCESSION   DACGLI010000175 DACGLI010000000
VERSION     DACGLI010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.189"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(37..993)
                     /locus_tag="IXT22_002982"
                     /pseudo
     CDS             complement(37..993)
                     /locus_tag="IXT22_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          347 a          178 c          159 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcattcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aac
//
LOCUS       DACGLI010000176         1017 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.190, whole genome shotgun sequence.
ACCESSION   DACGLI010000176 DACGLI010000000
VERSION     DACGLI010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.190"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            76..>1017
                     /locus_tag="IXT22_002983"
     CDS             76..>1017
                     /locus_tag="IXT22_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAQ4864272.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAF"
BASE COUNT          368 a          185 c          181 g          283 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
      361 cgaaaagaaa ggcctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
      421 atatttgata ttgacacact accgatgaaa ggtaaaagaa aacccaatgg ccatcaggaa
      481 aaacggggaa aacaacagta tcagcgctca atccatgatc gacctgataa ttatcctgat
      541 ttcaattctg agtttggtca ccttgaaggt gatacgatcg ttggcattca tcataaaagt
      601 gccgtcatta ctttagttga aagattatct aaagtcatta tcacgattaa acccaacggc
      661 cgtaaggcat tagatattga aactgccctt aatcaatggt tttctcgctt ccctaaaaac
      721 ttctttaaat ctattacgtt tgactgtgga aaagaatttt ctaactggaa agccattagt
      781 aaccaacatg atattgatat atattttgcg gaccctggaa caccttctca acgcccatta
      841 aacgagaatt ctaacgggat tctgcgtcgt aatggactgc cgaaatcaat ggattttaga
      901 aaagtgaatc agacatttat ttccagtgtc agcaatcaac gtaatcatat tccaagaaaa
      961 tcattgaatt acagaacacc aatcgaaata tttttgagct atgtacaaga agcattt
//
LOCUS       DACGLI010000177          994 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.191, whole genome shotgun sequence.
ACCESSION   DACGLI010000177 DACGLI010000000
VERSION     DACGLI010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.191"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..>994)
                     /locus_tag="IXT22_002984"
     rRNA            complement(<1..>994)
                     /locus_tag="IXT22_002984"
                     /product="16S ribosomal RNA"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DACGLI010000178          988 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.192, whole genome shotgun sequence.
ACCESSION   DACGLI010000178 DACGLI010000000
VERSION     DACGLI010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.192"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            81..>988
                     /locus_tag="IXT22_002985"
     CDS             81..>988
                     /locus_tag="IXT22_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAQ4864273.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYI"
BASE COUNT          367 a          179 c          179 g          263 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcga
//
LOCUS       DACGLI010000179          912 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.193, whole genome shotgun sequence.
ACCESSION   DACGLI010000179 DACGLI010000000
VERSION     DACGLI010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.193"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            2..>912
                     /locus_tag="IXT22_002986"
     CDS             2..>912
                     /locus_tag="IXT22_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864274.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSN"
BASE COUNT          383 a          137 c          210 g          182 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgcttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgagaag atgtttgaac accagagaaa
      121 gaccaacggt cagccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 acgtttagaa aacaaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaggt
      241 agaaaaactt gaaagacaag aagagctaaa ggaaatgggc tataacaagt acggcggact
      301 ggatatgacg atcgataata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ccacgatccg aaaatatcaa cggaagttgg aaacattaga
      421 acagctgaaa gaaaaatcag aaaaaggaaa agaaaatatc ctccctgaag tacaagcgat
      481 cattgacagc ggacgagtga cgcaatggaa aaaaaatcca accatttatt ttttgaaagg
      541 ctatcgaaaa gttgctttag aactgaatga aaacggggga tttgaggaat caaaaaaata
      601 ccaagccacg tcggaagagg aaaaagcagc tgttcgtgaa ttacttgaag aggctgcacc
      661 aactgattct ctgaaggaga aagaaaaaga tcatttctat cgagtagaat tcaacgaaaa
      721 tgatccagaa aaaggattga aaagttatgg tggggagatc gtaacattag aattgatcga
      781 tcaacttaaa acgttggata accaatacgc tgcagaagca ggttattata aattctattt
      841 tgaagaagtg aagaacggag aagtagtaga tcagatccga atggatctag gggatggcgt
      901 caacagtaat ca
//
LOCUS       DACGLI010000180          911 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.194, whole genome shotgun sequence.
ACCESSION   DACGLI010000180 DACGLI010000000
VERSION     DACGLI010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.194"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..535
                     /locus_tag="IXT22_002987"
     CDS             <1..535
                     /locus_tag="IXT22_002987"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864275.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKIRPFIF"
     gene            562..>911
                     /locus_tag="IXT22_002988"
     CDS             562..>911
                     /locus_tag="IXT22_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864276.1"
                     /translation="MNENGEFEESKKYQATSEEEKAAVRELLEEAVPTDFLKEKENDH
                     FYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYYKFYFEEVKNGEVV
                     DQIRMDLGDGVNSN"
BASE COUNT          381 a          138 c          209 g          183 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgtttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgaaaag atgtttgaac accagagaaa
      121 gaccaacggt caaccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 gcgaatcgaa aataaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaagt
      241 agaaaaactt gaaagacaag aagagataaa ggaaatgggc tataacaagt acggcggact
      301 ggatatgacg atcgagaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcgg aaaaaggaaa agaaaacctt cttcctgaag tacaagcaat
      481 cattgacagc ggacgagtga cgcaatggaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc a
//
LOCUS       DACGLI010000181          890 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.195, whole genome shotgun sequence.
ACCESSION   DACGLI010000181 DACGLI010000000
VERSION     DACGLI010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.195"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..888
                     /locus_tag="IXT22_002989"
     CDS             <1..888
                     /locus_tag="IXT22_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAQ4864277.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DACGLI010000182          883 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.196, whole genome shotgun sequence.
ACCESSION   DACGLI010000182 DACGLI010000000
VERSION     DACGLI010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.196"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..860
                     /locus_tag="IXT22_002990"
     CDS             <1..860
                     /locus_tag="IXT22_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4864278.1"
                     /translation="FRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVR
                     TLNDKYVAIFMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNE
                     LLQDIYSRGVHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRK
                     EICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRR
                     TIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVT
                     DTLVSMFTE"
BASE COUNT          313 a          167 c          156 g          247 t
ORIGIN      
        1 tcttccgaaa aggtattacc atgtcggaaa tcgcagactt gattgagaaa atgtatgggc
       61 atcactacac gccccaaacc atgtccaaca tgactaaagt gctgactgaa gaagtaaatg
      121 catttaaagt tagaactcta aatgataagt atgtcgctat tttcatggat gctacttata
      181 ttccattaaa acggcaaacc gtctccaaag aagcaatcta tattgccatt ggtatacgag
      241 aagacggcac taaagaagta ctaagttatg cgattgctcc gactgaatcg acctacgttt
      301 ggaatgagtt gttacaggac atttactcca gaggggttca tgatgtctta ctgtttatta
      361 ccgatggctt aaaaggcatg aaagatacga ttcaccagat ttatcctaaa gctaaatacc
      421 aacattgctg tgttcacgtt tcccgtaata ttgctcataa agtacgtgtc aaagaccgaa
      481 aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa gaagcgaata
      541 ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg acgcagtcac
      601 tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt cgtagaacca
      661 tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac agccgtagaa
      721 aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt tttgatacat
      781 acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc gatacattag
      841 tttcaatgtt tactgagtaa ctaattattt tgcaggagga caa
//
LOCUS       DACGLI010000183          844 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.197, whole genome shotgun sequence.
ACCESSION   DACGLI010000183 DACGLI010000000
VERSION     DACGLI010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.197"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..735
                     /locus_tag="IXT22_002991"
     CDS             <1..735
                     /locus_tag="IXT22_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4864279.1"
                     /translation="KQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFI
                     GTMKKEFPIPISWTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEG
                     FSHPEMGHMLVVPHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWE
                     IEASYIAQCAYNTTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKY
                     IVTPALEDNAGTLGCLALAREAVLHS"
BASE COUNT          236 a          171 c          211 g          226 t
ORIGIN      
        1 aaacaatacc aagcagattt agcagggatt gggattggct catttgggcc tatcgatatc
       61 catcgcgatt ccgccactta tgggtacatt acctcgaccc cgaaagtggc atggcaaaat
      121 tttgatttca tcggtaccat gaaaaaagaa tttccgatcc cgatttcttg gacaacagat
      181 gtcaatgcgg ctgcctatgg tgagtatgtc ttcggcagtg gcaaaggatt gagcagtgtc
      241 gtttactata cgatcggtac gggtgttggc ggcggtgcct tacaagaagg gcgctttatc
      301 gaagggttta gtcatccaga aatggggcat atgctcgtcg tccctcatcc aaaagatgac
      361 tttgctggca gctgtccatt tcatggcaac tgtttagaag ggatggccgc tggacccgcc
      421 atcgaaaaac gcttagggaa aaaaggacaa gaggttgcag aagatgatcc ttattgggaa
      481 atcgaagcct cctatattgc tcaatgtgcc tacaatacaa ccttgatgtt ttctccagat
      541 gtgatcattt ttggcggtgg tgtgatgaaa caacgccata tgctgcaaaa cgtccacgac
      601 gcatttgcaa aattggtcaa tgggtatgtc gaaacacctg agttaagcaa atatatcgtg
      661 accccagcat tagaagacaa cgctggaacg ctcggttgtt tggcattggc tcgagaagcg
      721 gtcttacatt cataaacgaa aaaaggctct tcgacattta gtgttggtag agaaagatac
      781 aactgaaaat ttagtcataa ccagttaggc agagtgctta actggttttt gttttacttg
      841 gaag
//
LOCUS       DACGLI010000184          780 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.198, whole genome shotgun sequence.
ACCESSION   DACGLI010000184 DACGLI010000000
VERSION     DACGLI010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.198"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..>780
                     /locus_tag="IXT22_002992"
     CDS             <1..>780
                     /locus_tag="IXT22_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4864280.1"
                     /translation="TRYQLIKQLIRTKQHFLENLTYKCNTLAREMRDESTSLFSATLI
                     SLMTEDFTLDELAELPLEAFCDLLQEKGKGRFKQPEKIAKAIQRAITMSYRLGALAQE
                     SINVVLSVLVREIRALEKNIKELDKAIEQVIVVIPEYQCLTSIPGVGKVYAAGLIAEI
                     GQIERFEDQTKLAKYAGLSWKVNQSGNYQSQNTPLTKQGNRYFRYYLVEAANSVKNYL
                     PEYKAFYQSKYKEVPKHQHKRALVLTARKFTRLVDTLLRKH"
BASE COUNT          277 a          152 c          140 g          211 t
ORIGIN      
        1 gtactcgcta tcaacttatt aagcaattga ttcgtacaaa gcaacatttt cttgaaaatc
       61 taacgtacaa atgtaatacg cttgctcgag aaatgcgaga cgaatcgacg agtcttttta
      121 gtgcaaccct catttcactc atgacggaag atttcacatt ggatgaactt gctgagcttc
      181 ctttagaagc tttctgtgat ttacttcaag aaaaaggaaa aggccgtttc aagcaaccag
      241 aaaaaatcgc taaagcaatt caacgtgcaa ttaccatgag ttaccgccta ggtgctcttg
      301 cacaagaatc aattaatgtt gttttaagtg ttctcgtacg agaaatacga gcacttgaaa
      361 aaaatatcaa agaattagat aaagccatcg aacaagtaat tgttgtcatt ccagaatatc
      421 aatgcttaac cagtattcca ggcgttggta aagtctatgc tgccggttta atcgctgaaa
      481 ttggtcaaat cgaaagattt gaagatcaga caaaattggc aaaatacgct ggattaagtt
      541 ggaaagtgaa ccaatctgga aactatcagt cgcaaaatac acctctgaca aaacaaggaa
      601 atcgatattt tagatactac ttagttgaag ctgccaactc tgtaaaaaat tatcttcctg
      661 aatacaaagc tttttatcaa agtaaatata aggaggttcc aaagcatcaa cacaaacgtg
      721 cactcgtcct aaccgcaaga aaatttacgc gtctggtgga tacgctacta cgtaaacacc
//
LOCUS       DACGLI010000185          774 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.199, whole genome shotgun sequence.
ACCESSION   DACGLI010000185 DACGLI010000000
VERSION     DACGLI010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.199"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            349..747
                     /gene="spxA"
                     /locus_tag="IXT22_002993"
     CDS             349..747
                     /gene="spxA"
                     /locus_tag="IXT22_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAQ4864281.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          289 a          108 c          137 g          240 t
ORIGIN      
        1 ttaaaatgac agaaaacatt actattaaag aaataaaaaa cataaaaaat cttaagaaat
       61 cggtttcatt tagcttttga gataaaataa tagtacagtt ttatacgctg tttcatatgt
      121 ttagaaaatt tgaattagat ttgaaaactc taatttttaa atgataaaaa aagcgagaat
      181 gctggtttta ctgtatatta accttagata actttcattt ttttaaaaaa attatgaaaa
      241 aaaggtagct atttaaaagt tgattatgta taatagaaac agatgggaga ttattatgat
      301 cttctgttac aaaaaagtga ttcttatcac gaaaaggagt ggtgcacgtt gttaacatta
      361 tatacttccc caagttgtac ttcctgcaga aaggctcgtg cgtggttgca agaacatcag
      421 attccatttg ttgaacgtaa tattttttca gaaccattga acagttctga attaaaagcg
      481 attttacaaa tgacagaaga cggaacagaa gaaatcatct cgacacgttc caaagtattc
      541 caaaaactga acatggattt agatgatctg ccgttacaag aattattgga acttgtgcaa
      601 aacaatcctg gattgcttcg ccgtccaatc atgattgatg ataaacgtct gcaagttggt
      661 tttaatgaag atgaaattcg tcggttccta ccgcgcgatg tacgacaatt agaattacgt
      721 caagcacaat tgatggctgg attatagaag gataatacga aacttggaaa agac
//
LOCUS       DACGLI010000186          731 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.200, whole genome shotgun sequence.
ACCESSION   DACGLI010000186 DACGLI010000000
VERSION     DACGLI010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.200"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            23..>731
                     /locus_tag="IXT22_002994"
     CDS             23..>731
                     /locus_tag="IXT22_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4864282.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISN"
BASE COUNT          254 a          127 c          140 g          210 t
ORIGIN      
        1 gaattataag gagtgagtac aaatgaccta tacccatctt acaacggatg aacttgtaat
       61 gatagagtct tatttcaaaa taaatcaatc tgttgcgaaa actgcgcatt tcttgaatcg
      121 ttcaagacaa acgatccata aagtatacct gttcttcaag caaggaaaat cagccttaga
      181 gtactatcaa cagtataaga aaaacaaatc aaactgtggt agacgcccgc ttgttttacc
      241 tgaggaacaa tcagaatata ttcaaagaaa ggttgttcaa ggatggacac ccgatgtgat
      301 tgttggtcgt gcagcgtttc ctattcgttg ttctgctcgt accatttatc gtatgttcaa
      361 aaaggggcta tttaatcctt ctgacttacc gatgaaaggc aagcgtaaac caaatggaca
      421 tcaagaaaga cgtggaaaac aagctttccg tcgctctatt catgaacgtg aaaaagatta
      481 tagccaattc tcaaatgagt ttggtcacct tgaaggtgac actatcgtag gtttgaaaca
      541 taaaagtgct gtaattacct tagttgagcg attatcaaaa gttatcatca cattgaaacc
      601 gtgtggtaga caagcgattg atattgaaaa caaattaaat cattggtttg aatctgtacc
      661 gaaaaatcta ttcaaatcca tcacttttga ttgtggaaag gaattttcaa attggaaaca
      721 gatcagtaat g
//
LOCUS       DACGLI010000187          674 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.201, whole genome shotgun sequence.
ACCESSION   DACGLI010000187 DACGLI010000000
VERSION     DACGLI010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.201"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            154..417
                     /locus_tag="IXT22_002995"
     CDS             154..417
                     /locus_tag="IXT22_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4864283.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..>674
                     /locus_tag="IXT22_002996"
     CDS             417..>674
                     /locus_tag="IXT22_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4864284.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTH"
BASE COUNT          254 a           89 c          141 g          190 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcat
//
LOCUS       DACGLI010000188          666 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.202, whole genome shotgun sequence.
ACCESSION   DACGLI010000188 DACGLI010000000
VERSION     DACGLI010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.202"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            289..606
                     /locus_tag="IXT22_002997"
     CDS             289..606
                     /locus_tag="IXT22_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864285.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
BASE COUNT          243 a           74 c           95 g          254 t
ORIGIN      
        1 agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat
       61 aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat
      121 caacgaaagt atactttata tagtcataac gccgatggta actatgcact gtaacgataa
      181 tgctgctaaa atatcttttt acgaaaaaca tcacaaggaa aaacttaact atggtattat
      241 ctaaacataa ttttttcggt atttaatatt taattaggag gtaatatttt gcttttttat
      301 agtaatttta tcttaatagt agcgatatta ttacttctga atatatggat ttttgatagg
      361 agtagaaatg caagtatagg ttttagaact aaacgaagtc tgtcttctaa aaaaaattgg
      421 gtatactcac aaactatttt ttatggagga attgttttaa ttagtttact ttcttcaaca
      481 ctttattctt tgaatattat agatgtttcc acctcaaatt caatatctat tattggaatc
      541 attattgctg caattattac acaactgttt ttagtgtttg gagagaagaa aagaagtaaa
      601 aaatagaaaa actagtgata gttttggtga tataagaaaa acatatatgt ataaaaagaa
      661 gaaagt
//
LOCUS       DACGLI010000189          616 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.203, whole genome shotgun sequence.
ACCESSION   DACGLI010000189 DACGLI010000000
VERSION     DACGLI010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.203"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            51..>616
                     /locus_tag="IXT22_002998"
     CDS             51..>616
                     /locus_tag="IXT22_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAQ4864286.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTT"
BASE COUNT          223 a          103 c          120 g          170 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccac
//
LOCUS       DACGLI010000190          580 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.205, whole genome shotgun sequence.
ACCESSION   DACGLI010000190 DACGLI010000000
VERSION     DACGLI010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.205"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..525
                     /gene="tnpB"
                     /locus_tag="IXT22_002999"
     CDS             <1..525
                     /gene="tnpB"
                     /locus_tag="IXT22_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAQ4864287.1"
                     /translation="KMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLH
                     EKVMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQ
                     YKADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASIN
                     ILTEGLRLHSMGLA"
BASE COUNT          220 a           85 c          114 g          161 t
ORIGIN      
        1 aaaatggaaa agaaactaaa gcgtgaacaa cgcaaattgt ctaggcgtgc tttattggct
       61 aaaaataaag gtaccaatct atttgaagct aaaaattatc aaaaacaaaa acgcaaagta
      121 gctagattgc atgaaaaagt aatgaatcaa cgtactgatt ttctgaataa gttgagtaca
      181 gaaatgatca aaaatcacga tattatctgt attgaagact taaacacaaa aggtatgttg
      241 cgaaatcata aattagctaa aagtatttct gatgtttctt ggtcaaagtt tgtgactaaa
      301 ttacaataca aggctgactg gtatggacga aaaatcatca aagtagataa atggtttccg
      361 tctagtcaga tttgttcaga gtgcggacat aaagatggca agaaatctct tgaaattcga
      421 gaatggactt gtcctgtttg tcatactcat catgatcgtg atatcaatgc tagtatcaat
      481 attctgaccg aaggtctaag actacattct atgggattgg cttagatcca atcatcaaga
      541 accgtaggaa ctacggggat agcttggtaa ataagagaca
//
LOCUS       DACGLI010000191          569 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.206, whole genome shotgun sequence.
ACCESSION   DACGLI010000191 DACGLI010000000
VERSION     DACGLI010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.206"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(44..>569)
                     /locus_tag="IXT22_003000"
     CDS             complement(44..>569)
                     /locus_tag="IXT22_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAQ4864288.1"
                     /translation="LEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASL
                     VKEAFGRIPYSLTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVES
                     TYKSVKVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRI
                     LDNERGSDTSGEAA"
BASE COUNT          167 a          137 c           98 g          167 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggtt tggttatcaa
      361 attcctttcc ccggtctgta tgaaaaagct tgacgtctgt taaagaatac ggtatccgtc
      421 caaaggcttc ttttaccaat gaggcatctt tcttctcacc acaggaataa ccaataattt
      481 ctcgattaaa caaatcaagt attaagcaga tataatgcca ctttttcccc acgcgaacat
      541 aagtaagatc cgtaacgatg gcttccaat
//
LOCUS       DACGLI010000192          556 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.207, whole genome shotgun sequence.
ACCESSION   DACGLI010000192 DACGLI010000000
VERSION     DACGLI010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.207"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(152..346)
                     /locus_tag="IXT22_003001"
     CDS             complement(152..346)
                     /locus_tag="IXT22_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864289.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          171 a          113 c           88 g          184 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caatgtgatg ttaggatgat
      541 ttcatggaca cgattt
//
LOCUS       DACGLI010000193          528 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.208, whole genome shotgun sequence.
ACCESSION   DACGLI010000193 DACGLI010000000
VERSION     DACGLI010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.208"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(5..90)
                     /locus_tag="IXT22_003002"
     tRNA            complement(5..90)
                     /locus_tag="IXT22_003002"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IXT22_003003"
     tRNA            complement(107..178)
                     /locus_tag="IXT22_003003"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IXT22_003004"
     tRNA            complement(190..262)
                     /locus_tag="IXT22_003004"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IXT22_003005"
     tRNA            complement(280..361)
                     /locus_tag="IXT22_003005"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IXT22_003006"
     tRNA            complement(369..441)
                     /locus_tag="IXT22_003006"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IXT22_003007"
     tRNA            complement(445..517)
                     /locus_tag="IXT22_003007"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DACGLI010000194          517 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.209, whole genome shotgun sequence.
ACCESSION   DACGLI010000194 DACGLI010000000
VERSION     DACGLI010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.209"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            57..>517
                     /locus_tag="IXT22_003008"
     CDS             57..>517
                     /locus_tag="IXT22_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4864290.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYS"
BASE COUNT          191 a           72 c          105 g          149 t
ORIGIN      
        1 ataaatatgt tataatagta tcaaatgaat attgctaaaa gaaaagaggt aggaacgtgg
       61 tagcgaagaa atatgtaatc ggtaatttta aaggtggcgt aggtaaaagt acgtgcgcgc
      121 aaatgttagg gtttgaatca gcagttaatg aaggaaaaag aaccttgata attgacttgg
      181 atatgcaagg aaatacttct gatgtgatga acttaacgca tatgaacttc actaacgaag
      241 aaggaggcgg agaaggtgaa ccgattgttt acgaaaatac tgtgactgac gtgttgataa
      301 acaatcttcc acctaaagag gctgtctata aagtaatcaa taacctctat atacttccag
      361 cagacatgtc ctttgaaatg tatgatgatt ggatcaaaga ccaatataat gattcattat
      421 cccaattcaa atatatgaaa gaaaagctag aaccattatt tgatgagttt gacgtcatct
      481 atttagatgt cccaccttct atttctgtat atagtaa
//
LOCUS       DACGLI010000195          514 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.210, whole genome shotgun sequence.
ACCESSION   DACGLI010000195 DACGLI010000000
VERSION     DACGLI010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.210"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..132)
                     /locus_tag="IXT22_003009"
     CDS             complement(<1..132)
                     /locus_tag="IXT22_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4864291.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DACGLI010000196          510 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.211, whole genome shotgun sequence.
ACCESSION   DACGLI010000196 DACGLI010000000
VERSION     DACGLI010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.211"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..442)
                     /locus_tag="IXT22_003010"
     CDS             complement(<1..442)
                     /locus_tag="IXT22_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4864292.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGL"
BASE COUNT          170 a          113 c           90 g          137 t
ORIGIN      
        1 ttaaacctaa cccatgtaat agctgaacga tcatactgga tcctgaggag gtgatcccgc
       61 caaataactg aacggtaatg atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag
      121 cgagtaataa cagtttcaag ctgtttttat ctttgccgag atatcttggc aaaatcaatc
      181 cagcaagcaa gcctgtgaga atttggattg gcgaataata cagagaaaaa atatctgtag
      241 tcactccact taaaataccg ctggacaatc ctgtcagcat tccaggtaca ggcccaagca
      301 atgcaccagc aaaaatcgtt ccgatagaat cgagatagat tggcaaacga agccataaag
      361 caatcgttcc tccaatataa ttgatcccaa tacacaaagc catcactgta agtacgcgag
      421 ttgccatttt gtttttattc attttgttag cccatcttta acctttccaa atctttcata
      481 atcgtttctt cttgtgcatt taaaagaacg
//
LOCUS       DACGLI010000197          479 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.212, whole genome shotgun sequence.
ACCESSION   DACGLI010000197 DACGLI010000000
VERSION     DACGLI010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.212"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
BASE COUNT          162 a           69 c           86 g          162 t
ORIGIN      
        1 acaaaagtat cttcgattaa tacttgctca agttatgtgc agctacgaaa aagtaggtac
       61 cgaggtactt tctttttcgc agcttttttt ggacttatga gaagtacatt cgctggaaga
      121 atacgatata aaacgagctt tttcactaaa gatattaata gagtgaaaga aacaagcttt
      181 tgttgtcagt tttttcactt ttctaaaaat gaaaataaaa aattctggaa gtggagaaga
      241 attttgcttg ctatactttg tcttgtagaa aagaggtaga caaaataatg caagctcaaa
      301 taagcgattt tccataacct tggtaggaat gacaaattaa ataggaaagg gaagtaataa
      361 tatgaataaa aaaaagttat ctctattcgg tttttttgcc ctgacagctt ccatggtttt
      421 gactgtttat gagtatccga cctttgcaac atcacaatta catttggttt tctttcttc
//
LOCUS       DACGLI010000198          462 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.213, whole genome shotgun sequence.
ACCESSION   DACGLI010000198 DACGLI010000000
VERSION     DACGLI010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.213"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(<1..430)
                     /locus_tag="IXT22_003011"
     CDS             complement(<1..430)
                     /locus_tag="IXT22_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4864293.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DACGLI010000199          460 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.denovo.214, whole genome shotgun sequence.
ACCESSION   DACGLI010000199 DACGLI010000000
VERSION     DACGLI010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.denovo.214"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(20..91)
                     /locus_tag="IXT22_003012"
     tRNA            complement(20..91)
                     /locus_tag="IXT22_003012"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="IXT22_003013"
     tRNA            complement(113..200)
                     /locus_tag="IXT22_003013"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="IXT22_003014"
     tRNA            complement(225..298)
                     /locus_tag="IXT22_003014"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="IXT22_003015"
     tRNA            complement(312..382)
                     /locus_tag="IXT22_003015"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="IXT22_003016"
     tRNA            complement(384..459)
                     /locus_tag="IXT22_003016"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DACGLI010000200        56552 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.011, whole genome shotgun sequence.
ACCESSION   DACGLI010000200 DACGLI010000000
VERSION     DACGLI010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.011"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            202..2301
                     /locus_tag="IXT22_003017"
     CDS             202..2301
                     /locus_tag="IXT22_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4864294.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            2497..3360
                     /locus_tag="IXT22_003018"
     CDS             2497..3360
                     /locus_tag="IXT22_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4864295.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            3465..3938
                     /locus_tag="IXT22_003019"
     CDS             3465..3938
                     /locus_tag="IXT22_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4864296.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            4034..4921
                     /gene="xerD"
                     /locus_tag="IXT22_003020"
     CDS             4034..4921
                     /gene="xerD"
                     /locus_tag="IXT22_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4864297.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            4940..5311
                     /locus_tag="IXT22_003021"
     CDS             4940..5311
                     /locus_tag="IXT22_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4864298.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            5281..6078
                     /locus_tag="IXT22_003022"
     CDS             5281..6078
                     /locus_tag="IXT22_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4864299.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            6062..6631
                     /gene="scpB"
                     /locus_tag="IXT22_003023"
     CDS             6062..6631
                     /gene="scpB"
                     /locus_tag="IXT22_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4864300.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            6637..7353
                     /locus_tag="IXT22_003024"
     CDS             6637..7353
                     /locus_tag="IXT22_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4864301.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      7435..7560
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7683..8294
                     /locus_tag="IXT22_003025"
     CDS             7683..8294
                     /locus_tag="IXT22_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4864302.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            8672..10195
                     /locus_tag="IXT22_003026"
     CDS             8672..10195
                     /locus_tag="IXT22_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4864303.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            10432..11772
                     /locus_tag="IXT22_003027"
     CDS             10432..11772
                     /locus_tag="IXT22_003027"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4864304.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            11925..12662
                     /locus_tag="IXT22_003028"
     CDS             11925..12662
                     /locus_tag="IXT22_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4864305.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(12827..13048)
                     /locus_tag="IXT22_003029"
     CDS             complement(12827..13048)
                     /locus_tag="IXT22_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4864306.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            13079..14110
                     /locus_tag="IXT22_003030"
     CDS             13079..14110
                     /locus_tag="IXT22_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864307.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            14097..15500
                     /locus_tag="IXT22_003031"
     CDS             14097..15500
                     /locus_tag="IXT22_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4864308.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            15566..16201
                     /locus_tag="IXT22_003032"
     CDS             15566..16201
                     /locus_tag="IXT22_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4864309.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            16250..16930
                     /locus_tag="IXT22_003033"
     CDS             16250..16930
                     /locus_tag="IXT22_003033"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4864310.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            17065..18294
                     /gene="rpsA"
                     /locus_tag="IXT22_003034"
     CDS             17065..18294
                     /gene="rpsA"
                     /locus_tag="IXT22_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4864311.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            18476..19786
                     /locus_tag="IXT22_003035"
     CDS             18476..19786
                     /locus_tag="IXT22_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4864312.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            20029..20304
                     /locus_tag="IXT22_003036"
     CDS             20029..20304
                     /locus_tag="IXT22_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4864313.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            20539..21585
                     /locus_tag="IXT22_003037"
     CDS             20539..21585
                     /locus_tag="IXT22_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864314.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            21587..22846
                     /locus_tag="IXT22_003038"
     CDS             21587..22846
                     /locus_tag="IXT22_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4864315.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            22852..23433
                     /locus_tag="IXT22_003039"
     CDS             22852..23433
                     /locus_tag="IXT22_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4864316.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(23515..24390)
                     /locus_tag="IXT22_003040"
     CDS             complement(23515..24390)
                     /locus_tag="IXT22_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4864317.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            24538..24870
                     /locus_tag="IXT22_003041"
     CDS             24538..24870
                     /locus_tag="IXT22_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4864318.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            24982..26190
                     /locus_tag="IXT22_003042"
     CDS             24982..26190
                     /locus_tag="IXT22_003042"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4864319.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            26344..26799
                     /locus_tag="IXT22_003043"
     CDS             26344..26799
                     /locus_tag="IXT22_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864320.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            27161..27436
                     /locus_tag="IXT22_003044"
     CDS             27161..27436
                     /locus_tag="IXT22_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864321.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            27449..29527
                     /locus_tag="IXT22_003045"
     CDS             27449..29527
                     /locus_tag="IXT22_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4864322.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            29687..31573
                     /locus_tag="IXT22_003046"
     CDS             29687..31573
                     /locus_tag="IXT22_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4864323.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            31585..32532
                     /locus_tag="IXT22_003047"
     CDS             31585..32532
                     /locus_tag="IXT22_003047"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4864324.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            32552..33079
                     /locus_tag="IXT22_003048"
     CDS             32552..33079
                     /locus_tag="IXT22_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4864325.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(33142..33795)
                     /locus_tag="IXT22_003049"
     CDS             complement(33142..33795)
                     /locus_tag="IXT22_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4864326.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            33927..34769
                     /locus_tag="IXT22_003050"
     CDS             33927..34769
                     /locus_tag="IXT22_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4864327.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            34927..35823
                     /locus_tag="IXT22_003051"
     CDS             34927..35823
                     /locus_tag="IXT22_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4864328.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            35826..36539
                     /locus_tag="IXT22_003052"
     CDS             35826..36539
                     /locus_tag="IXT22_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4864329.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            36559..37077
                     /gene="msrA"
                     /locus_tag="IXT22_003053"
     CDS             36559..37077
                     /gene="msrA"
                     /locus_tag="IXT22_003053"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4864330.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            37074..37301
                     /locus_tag="IXT22_003054"
     CDS             37074..37301
                     /locus_tag="IXT22_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4864331.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            37453..38004
                     /gene="lepB"
                     /locus_tag="IXT22_003055"
     CDS             37453..38004
                     /gene="lepB"
                     /locus_tag="IXT22_003055"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4864332.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(38087..38629)
                     /locus_tag="IXT22_003056"
     CDS             complement(38087..38629)
                     /locus_tag="IXT22_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4864333.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38866..39264)
                     /locus_tag="IXT22_003057"
     CDS             complement(38866..39264)
                     /locus_tag="IXT22_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4864334.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            39524..40384
                     /gene="ylqF"
                     /locus_tag="IXT22_003058"
     CDS             39524..40384
                     /gene="ylqF"
                     /locus_tag="IXT22_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4864335.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            40377..41144
                     /locus_tag="IXT22_003059"
     CDS             40377..41144
                     /locus_tag="IXT22_003059"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAQ4864336.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            41200..42057
                     /gene="dprA"
                     /locus_tag="IXT22_003060"
     CDS             41200..42057
                     /gene="dprA"
                     /locus_tag="IXT22_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAQ4864337.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            42179..44257
                     /gene="topA"
                     /locus_tag="IXT22_003061"
     CDS             42179..44257
                     /gene="topA"
                     /locus_tag="IXT22_003061"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAQ4864338.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            44226..45602
                     /gene="trmFO"
                     /locus_tag="IXT22_003062"
     CDS             44226..45602
                     /gene="trmFO"
                     /locus_tag="IXT22_003062"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAQ4864339.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            45800..46705
                     /gene="xerC"
                     /locus_tag="IXT22_003063"
     CDS             45800..46705
                     /gene="xerC"
                     /locus_tag="IXT22_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAQ4864340.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            46742..47290
                     /gene="hslV"
                     /locus_tag="IXT22_003064"
     CDS             46742..47290
                     /gene="hslV"
                     /locus_tag="IXT22_003064"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAQ4864341.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            47304..48704
                     /gene="hslU"
                     /locus_tag="IXT22_003065"
     CDS             47304..48704
                     /gene="hslU"
                     /locus_tag="IXT22_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAQ4864342.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            48722..49513
                     /gene="codY"
                     /locus_tag="IXT22_003066"
     CDS             48722..49513
                     /gene="codY"
                     /locus_tag="IXT22_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAQ4864343.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            49595..50470
                     /locus_tag="IXT22_003067"
     CDS             49595..50470
                     /locus_tag="IXT22_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAQ4864344.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(50602..51240)
                     /gene="plsY"
                     /locus_tag="IXT22_003068"
     CDS             complement(50602..51240)
                     /gene="plsY"
                     /locus_tag="IXT22_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAQ4864345.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            51367..51801
                     /locus_tag="IXT22_003069"
     CDS             51367..51801
                     /locus_tag="IXT22_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAQ4864346.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            51967..54012
                     /gene="parE"
                     /locus_tag="IXT22_003070"
     CDS             51967..54012
                     /gene="parE"
                     /locus_tag="IXT22_003070"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAQ4864347.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            54024..56474
                     /gene="parC"
                     /locus_tag="IXT22_003071"
     CDS             54024..56474
                     /gene="parC"
                     /locus_tag="IXT22_003071"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAQ4864348.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
BASE COUNT        19609 a         9659 c        12027 g        15257 t
ORIGIN      
        1 atcaattctg attcatcagt cccataaatt atagagccaa aaaaagcttg agactacgca
       61 gtctcaagct tttttttcta taggaaggaa attcattcat tatttttaag taaatcctaa
      121 aaataagcta ttggcgtgac gtatagaata tgatagatta aatggtagcg taaacctagt
      181 aaaggagccg atcgctaagt gatgaaaaaa tgtccaaatt gcggatcgaa aaaaatggag
      241 cagaatacta tctgtccaga ctgcggtcat caaataactg cagaagatca gcaaataaaa
      301 gaatcaattg aagaaacaaa tacagatgca gctatgcagg ataaatcaac tgaagatgca
      361 gtctttcctg atacagaatt aaacgatcca atcgaatggt cggaattgaa agatttacct
      421 ctagaatctg taatggaatt attcgaaaaa gcagaaccag aagacgaaga accacctgct
      481 cacgatcaag taactaatat agagaaaaat gaacagaaga aagcaactgt tcatgagact
      541 tcggaagaat caggaaagaa tcaagaagaa acgcttgaat caaaacaaaa aagaagagta
      601 gctgaactga aagaaatcgt cgataatgag gaagaaaatt cgatactatc cgcttatatc
      661 aaagcacatc gtgaagatac aaaagaagag cacgcgaaag agctgctcaa aatgatcagt
      721 gaaaaaattg cacaggaaaa caaagtagag ccagaaaagg aacaagaaac tgaaaaagac
      781 tctgatagag aaaacgccac aggtaaagaa acagtaaaaa taaaagacgt aaaaacggat
      841 atcacagaaa aaactgaagt atttactgaa aaacaattag aaaaggaaaa aacgaataaa
      901 ctgccggaag cagagaaaaa agaaatactc gaaaacacag acaaaaagtc aacagagccc
      961 gatgaaataa atagtgaatc cgatgctgaa aatcaatctg taagcaaaga gggtactgat
     1021 cttgaagcaa aaatagaaaa agaagagaac cagcctaagc tgtttgaagc agaagcgaaa
     1081 tcaataacaa tcgtgccaga tactgaaaaa acacatcaag aatcaaactt agaaaaaaca
     1141 gatccagata aagcgcaaaa gaaaaaatca aaaaaagtac cttatctcgt tttagcagca
     1201 gtacttctac tcggtggagg aagctgggct tattatgacc atcatcaaaa agtagaagcc
     1261 gaagtagcag cagaagcaaa aagacagcaa caaatggaag aacttcatga gaaacttgct
     1321 gccttttata cagatgatca ccatcaattt attcgtgcag atatgattca tcaagattta
     1381 tcaaaactaa aaaatgattt atccagtctt aagaatgaaa aaggatattc agagttagaa
     1441 acaacttacc aagatatcca atctaagatc cgagatatcc aaaaagtgaa tgagtggttc
     1501 atagcacctg ccatcgtcga tgatcatcta gcagatgaca tcaagttgaa agcagataaa
     1561 gagatccaag caatcgaaac ggataacaca gattttggaa aattgattca acaagcacaa
     1621 acagaagcta aaaatcaata tgctgaattg caaacagcta aagaaaaaac agctatagtc
     1681 tttaaagacg gaaaagtagt ggattcagca acacgcgacc aatacaagac ggcaaaagaa
     1741 gcagtagaaa aagtgaaaaa tacagatcta tctgctcagt tgaatgaaca attgaaacaa
     1801 gtagataaga tgctcactga taaagagaaa aaagaagaag aggaaaagaa aaaagcagaa
     1861 gaagcgaaaa aagcagctga agaacaagca aaacaagccg ctcaagcagc agctgcagct
     1921 caagccgctc aacaagctgc ggtcgcacaa gcagcacagc aagaagcggc atcctcgacc
     1981 ccttcctctt caaactcagc gaatcagcca atcaaatctg ccagagcaag tgatattgcc
     2041 gatgcatcta atccagcatg gacgtgggca ccaggtgtcc aaagcaaagt gattgctaca
     2101 tgtatccaac gtggatatat cgttgaagga ggttacagat tagaaaaagc cagaatcgaa
     2161 aatggggaag gctattataa tctatatgcc acttcaacaa aatctgcatt gatgaaaggc
     2221 attggagaaa gtgctttgcc attttacatc gtaaccatca actgtaaaac tggatggttc
     2281 ggaggaaatg ggagcaatta attttaggca aatgaaagag gctgtgagcc tgccgtttaa
     2341 caccgtttat tcgaaaaagg ggagtatgac acaactgttg tcatactcct tttttcacct
     2401 ttccaaacca aggctcagct attcaagtag ataacattat gttatgatag caaagaaatg
     2461 tattaagaaa acctttcact atagagggag aaaaaaatga acgatttatt agcaactata
     2521 tttacaggta ttattattga tgaaaatgaa aaaaactact ttgtccaaaa aaacggacaa
     2581 acctttggct taagcaaatc agaaggtgaa cacaaaatcg gtgaagcagt tgaaggattc
     2641 ggttaccaaa atcaaaaaca tgaaaatcgg atcactacac aaattcctaa aagccgtatc
     2701 ggtcattacg gttttggaat cgttactgct acacgaaaag atttaggtgc gtttgtcgat
     2761 atcggtcttc cagataaaga ctttgtcgta tctcttgatg aattgccgac aatgacagag
     2821 ctatggccta aaaaagggga tcgcttgatg atttccctta gagttgatgc aaaagaccgt
     2881 atttggggca gtttagcaga tgaaaaaata ttcaaatctt taagcaaata tggaacagaa
     2941 gaaatgaaaa acaaagatgt gataggaaca gcataccgct tgaaattaac aggtacgtac
     3001 gttttaacgg aagatttcta tcttgggttt atccatcctt ctgaacgata taatgaacct
     3061 cgtctaggcg agcagataaa aggtcgagtg attggtgtcc gaccagacgg tgtactgaat
     3121 ctttcattga agccaagagc atatgaagct atatcagatg atgcacaaat gattttaacc
     3181 attttagaac gttctgcaga tcagcaaatc aactttacag ataaatcgga tccagaagaa
     3241 atcatgaaag cttttggtat cagcaaagga gcatttaagc gcgcattagg taatcttttg
     3301 aaacaaggat tgattacaca agaaaacggt gtgacaaaac tagtcaaaaa atctaattga
     3361 gaatcccttg catgtttttc ttaactagct tataataatt ttaattaaca tagtgttata
     3421 tcttttttta tttgtaatta ttataaattg ttggggttga gtaaatggtc atgaatgcta
     3481 tttcggcgat gaaaaaaaca aaacagcagc tacatgaagc ggggtttaag ctgacaccgc
     3541 aaagagaagc tactctgctt gtgcttttgg aaaatgagaa agagcattta tctgcagaag
     3601 aaatcttctt tttagtgaaa aaaaagagtc cggaaattgg acttgctact gtttatcgaa
     3661 cccttgaaat cttgacagaa ttgaaaattg tcgataaagt aagttttaat gatggattag
     3721 cccgttatga tttgagaaaa gaaggcgcca aacatttcca tcatcattta ctatgcttga
     3781 actgcggcac gatcgaggaa gtagaagagg atcttttact tgaagtggag caagtagtag
     3841 aagaacgtta tcatttttta gtaaaagatc atcggctaac gttccatgga atctgtcagg
     3901 aatgctatga aaaagaaaaa agaaaccagt ccgtctgagt gtctagacgg ctttttcttt
     3961 gctcagatta tggaaaaaga ctatcagaat gaagcggtat ctgatatgat agagaggcat
     4021 gagggggatt attatgaaag agcaaatcaa cgattatctc cactacttga atattgaacg
     4081 gggattgtcc gccaatacac gacaaagcta tgaacgtgat ttggaacagt acttgcattt
     4141 tctacaggag cagaaaattg cttcatggca ggatgtcgat cgctttttag tcatccgttt
     4201 tctggagaag ttgcatgaag aaaaaaaagc gacagcaact gttactcgga tgatctcaag
     4261 tctcagaaga ttccatcagt ttttacggca agagcgtatc actgatcatg atccgatgca
     4321 acatatcgat acgccgaaga aagcacagaa attaccaagt acattgactc tgacagaagt
     4381 agaaaagctg attgaagcac ctgatacgac aaaaacgtta gggataagag atcgtgcaat
     4441 cttggaagtc atgtatgcta ctgggatgcg cgtcagtgaa ttgattggat tgaaattggg
     4501 agatcttcat ctttctcttg gactggtaca gacagttgga aaaggagata aagagcggat
     4561 cattccttta ggtgattatg cgatccaatg gctggaacgc tacttagacg aagcacgtcc
     4621 attacttgta aaggacgcat ctgaaatgca tgtatttgtc aataatcatg ggaaaggtct
     4681 ttctcggcaa ggaatctgga aaaatctgaa gcagttagta cgagaggctg ggatttacaa
     4741 agaagtaaca ccacatacgc tgcggcatag ctttgccaca catctgctag aaaatggagc
     4801 tgatttgcgg acagtacagg aattgttagg tcacgcggat atctctacga ctcagattta
     4861 tacacatatc acgaagaaaa gaatgacgga tgtttataag cagcattttc caagggctta
     4921 gtcataggaa ggtgagaaga tgttaacaca ttaccggaaa gaaaaccgta aaattgctat
     4981 gggactattg agtttccata agaaactgac aggtaaaact tctttgttga aggagattga
     5041 tacgtacgaa tctgaagacg attatgaact ttttttcttt acgccagaag gttcaaccaa
     5101 cattcaaggg attattggta tttactgggc aacgaacgat cagctgatca tccatgacat
     5161 ttctttgaat ccgtcttatc gcggtgagaa tatgggcttt caaatgttag atgaattaca
     5221 ggaaaagtac ccggatgtct ccatccgtgc aactgaaatc acagagcctt acattggaaa
     5281 atggctagca aagaaaaaga agaaagagtg aatgagttga cggagatcaa tattaaatta
     5341 gatgtattcg agggtcctct cgatctgctg cttcatctga ttcagcaaat ggaaatcgat
     5401 atatatgata taccgatcgc tacgatcacg gagcaatata tgaattatat ccatacaatg
     5461 aaaacactcg agctagctgt tgcaggagaa tacttagtga tggctgctac attgatggca
     5521 atcaaaagca agacattgct tcctgtccaa gaattcgtca cagacgatga agaattatgg
     5581 gaagaagatc ctcgagaaga attggtcact cagcttttag aataccgtaa atataaatat
     5641 gcagctgaaa gactgacaga aaaagcagag gaacgaagtc tttattacac aaaagaacct
     5701 atgaacatcg atgggttagc ggatgctgaa aagccgttga agcgaggaca agtcaaaaaa
     5761 atcgatttga tccgtgccat gcagaaaatc ttagaacgta agaaattttc tcaaaaagtg
     5821 gaaaaaacga tcacgcccga tgacacaacg atcgaagaac gaatggtatt tatcgaagag
     5881 cgtataaaaa gaaatgcgca tggctgtact ttcgattctt tttttgagtc accttctaaa
     5941 agtgaagttg tcactacttt tatggctttg ctagaattga tgaaaaaagg gcagatcatt
     6001 gcgcaacaaa aagaaaacta tgaatcaatt atgctttatc cagcagtagg agataccgaa
     6061 catgacgaaa ttaagtgaac ttgaagccct tctttttatt gttggcgagg aagggatcag
     6121 taatgaagaa ttaagcggac tgttaaatct cagcgaagca gaagtcacaa gtttagtgaa
     6181 agaattaaaa gaatcttaca ctcaaaactc gcactcagct ttgcatattt ttgaaacgga
     6241 aagccattat gtattaacga ctaaaaaaga gctggctccc ttacttaagc gatatgcgca
     6301 agggacatca aacacattat ctcaagccgc cgtcgaaacc ttagcaatca tcgcttataa
     6361 acagccaatc acaagagctg aaatcgagca gattcgagga gttcaggttt caggagcggt
     6421 acagcgtcta gctgcccata aactgattga agaaaaaggt agagtagaag gaccaggtcg
     6481 gccgatatta tatggaacaa ctggctactt cttagattat tttggtttga aatcattaga
     6541 agaactgcct gatacacaag aaatggaaat ttcacttgaa gaagacgtgt caccagatct
     6601 attctttgat ggaatgaata aaggagaata attgtaatgg agagattgca gaaagtaatt
     6661 gcccacgctg gcatcacttc tcgtcgaaaa gcagaagaat tcatccttgc aggacgtgta
     6721 aaagtaaacg gacaagttgt aagggaatta gggataaaag ttgggaaaca tgacactgtg
     6781 gaagtggatg aagtcccaat ttatcaagaa gaatacggtt actatttatt gtacaaacct
     6841 aaaggagtta tttctgctgt tgcagatgac aaaggaagaa aagttgttac ggatcttttg
     6901 ccgatggtaa aagaacgtat ctatcctgta ggtcgactgg attacgatac ttcggggatc
     6961 ttgctactga caaatgatgg agattttgct cagcgcctga cacatccaaa acatgaagtg
     7021 gataaagttt acgttgcaaa ggtaaaaggg atcgctacaa aatcgatgct tgcacctttg
     7081 acaaaaggaa taaagatcga aggacgaaaa acatctccag ctaaattcca aattttatca
     7141 gtggatccta agacaaacca cagtatcgtg gaattgacga tccacgaagg acgtaatcat
     7201 caagtgaaaa atatgcttca agcagttggt cttcctgtgc aaaaactaaa acgtgaaaaa
     7261 tacggagatc tgactttaca aggcctacgt cctggggatt accgtgaact gaacaaaaaa
     7321 gaagtcagca gtttgctgaa ccactcaaaa tgaacactta ctttttataa gtgttagatg
     7381 ttgcgttttt tgaatagata tgtataatga atatgtaaac aaaaattata taaggttcgt
     7441 cttcaggggc agggtgaaat tcccgaccgg tggttatagt ccacgaccta ttttgcaaaa
     7501 aaatagctga atcggtgaaa ttccgatacc gacagtatag tctggataaa gaagatagag
     7561 cttatttgac gacgcttgat caaataactc taactctatt ttccctggaa aatagagttt
     7621 tttcatttgg agagaaacgt caaaaagttc gctgaagagg agtcctaaca ggaggatttc
     7681 aaatgaagaa cacccgtgta cagaaaatgg ttgcagtagc gatgtttgct gcgatcgcat
     7741 tagttttaca gtattttgct tttccgatca tgccggcttt tagttttttg aagatcgatt
     7801 ttagtgatat ctcggtattg atcagcatgt tcttattcgg tccagcggcc ggagttgcaa
     7861 cagcgttctt gcgttcagta ttacatctgc tgactacagg tttttctccg gataatttgg
     7921 taggagacac tgctagtttc ttatcaacaa cgatctttac attcccgatt tattatttct
     7981 ttagtgtaaa gaaacagcat aaaggaagaa acaaattttt aggtgtcatt acaggaacca
     8041 tcgctctaac tatttttatg agtatcgcaa attatttcgt tattacgcct ctttacttaa
     8101 tgtttttagg gctgaacgca acacagatgc tgggcatgtc tttagcaaac tatgtactga
     8161 ttgggatcgt tcctttcaac ttgatcaaag gattcatcgt gagtgctgtc tttttagtgc
     8221 tgcatgcgca acttcttcca tggttaagtc gaaaacaaca tcagttcgaa caacgtcata
     8281 cagcagtcaa ataaatatca aaaagatcaa gaaatttctt ggtctttttt tttggaaaaa
     8341 aatacaagac atgcaataat gtaaacgttt tatttgtttg ttttgagtat ttttttgatt
     8401 tatgcataaa aatcaatcaa ttctttgcaa atgtgaaatt cttctccttt taaaagacga
     8461 aaatgtttgt ttataaaaaa aaggaaacgc tacaatgaaa aagaagaaag ctttaaaaac
     8521 ctgaaaaaag aggagggaat agggaaaaac gaactttttg aacaaaagtt ttacaaaatg
     8581 cgtgttatta tttttgttct gatactcttt ttgataaaat aacattagag ccaaaattgt
     8641 tgtctctaac ggaaaagaaa ggaagaagaa gatggaacaa acaaaaaaga aaaaatttca
     8701 aatgccttca gcgtatacgg tcttatttat tattattgca gtaatcgctg tacttacttg
     8761 gtttatacca gctgggcact atagtgtaga cgatgcaggc aacatcgtcg ctggatcata
     8821 tgaacgagta caacaaaatc ctcaagggct gtgggatatt ttcatggcgc caatcaatgg
     8881 gatgctaggt gtaccagcgg gggagctaac taaagaaaca cctgctgcaa tcccaatctc
     8941 tttcttcatt ttggttgttg gtggattttt aggtattatc aacaaaacag gggcactaga
     9001 tgccgggatt gcttcagttg tgaagaaatt caaaggaaaa gaaaaaatgc ttattccagt
     9061 attgatgctg ttatttgcat taggcggctc tacttacgga atggcagaag aaacgattcc
     9121 attctatgct ttactgatcc cagtcatgat ggctgtaggc tttgatacag tagtagctgt
     9181 agcaatcgta ttagtagggt ctcaagtagg ctgtctagct tcaacggtaa atccttttgc
     9241 aacaggcgta gcttcacaag ctgttgggat ttcgatgggt gaaggtattg gtcttcgatt
     9301 cttgatgttc gttattttgt tagctatttc tattgtatat gtgtatcgtt atgcatcaaa
     9361 gatcgaaaaa gatccaacaa aatcattagt atacaaccaa cgtaaagaag atatgaagca
     9421 tttcgatatt gaagcaatcg gtcgtcaaga agtaatcacg aaaaaacaaa aacatgttaa
     9481 tgtattgttc tttattactt ttggtatcat gatcatcagt ttgattcctt ggacaacctt
     9541 gaatgcgaat ttcacgattt ttgaatcatt gacaaactgg ttaacaaacc ttccggtact
     9601 aggtacggtt ctaggtaaaa gcatgcttcc attaggtgac tggtacttcc cagaaattac
     9661 tatgttattc ttagtaatgt ccatcgtagt agcaatcact tatggcatga aagagtctga
     9721 atttgtctct gaatttttag ctggtgcttc tgatttgatc ggtgtagcaa tcgtagtagc
     9781 tgttgctcgt ggtatccaag tggttatgaa caatggatta atcacagaca ccatcttaca
     9841 ttggggcgaa caaggattaa gttcattatc ttcaagtgta ttcatcatta ttacatttat
     9901 tttctatatc cctatgtcat tcttgattcc ttcaacttcc ggcttagctg ctgcaacaat
     9961 gggaatcatg ggacctatgg gtgaatttgc cggcgtcggt aaggatttag taatcactgc
    10021 ttatcaatct gcatctggtt tagtaaactt aattacacca acatctgcta tcgtaatggg
    10081 tgctgtagca attgctcgtt tcgatgtttc agtgtggtgg aaatttaccg gtaaattaat
    10141 tgcgatatta tttgtagcca tctgtgtgat cctaggtgta gcagcaatgt tctaaaccta
    10201 gacaaataca ggtacaaggt ctatcataag aatgaagaaa ccgataaacg gctatcgata
    10261 agcacgtgga taagtcaata gctccattca gtgagtgttt tttctttcat catttgttaa
    10321 gaacattctg cttgctgatg gagcaggctt aaaacgtcat tatttgagaa gaagaggttg
    10381 tgtcggagga atttgacatg acccttttta acatattagg aggataatat catgaaaaaa
    10441 tttgtgacag aacaacatca tgaacaagca ttagaatcat tgagcgaatt gatccgaatt
    10501 ccttccgtac tagatgaagc agattcagga caaggacatc ccttcggtaa aaaagtgatt
    10561 gaagctttgg ataaagtatt ggaaatcagt gaaaagctag gatttagaac atttaaagat
    10621 ccagaaggct attacggtta ttcagagatt ggctctggag atgaattatt cggtatcttg
    10681 tgtcatatgg acgttgttcc agcaggggac gaaaataatt gggaaacaaa accattcgat
    10741 ccaactataa aagacggctg gttagttggt cgcggatccc aagatgacaa aggtccttct
    10801 attgcggcaa tgtatgccgt caaagctttg attgatgctg gcgtggaatt caagacacgt
    10861 attcgtttta tctttggtac agatgaagaa aatttatggc gttgtttaga aaaatataac
    10921 gaaaaagaag aaggaattac gcaaggattt gcgccagatg ctgaatttcc tttaatttat
    10981 gcagaaaaag gcttattgca agcttacttg acaggaccag gaacgaacga gttttctgta
    11041 aaagctggag gagcgttgaa tgttgttcct gatgcagctc cttactctgg agaaaagctt
    11101 tctgaagtaa aagaagcatt gaaaaaacac gaattcgatt tcgaagaaca aggtgaaggc
    11161 atcgtcgttc ttggtaaaag tatccacgcg aaagatgcag cacaaggagt gaatgctatt
    11221 tctcgtctgg caattgctct ttcagaagta tttgattttg gcccaatcaa tttcttagga
    11281 aaattagttc aagaaaatgc aactggtgaa gctgtcgtgg gcaaaacaga agatgaacaa
    11341 tccggcgagc taacgatgaa ctttgcaagt ttggaaatca caccagaaca aacaaaaatc
    11401 ggtgtagata tgagaatccc tgttacattc aagaaagatg atttagtagc taaattaact
    11461 aaaacagcag aaaaatatgg gttgacttat gaagaatttg acttccttga ttcattatac
    11521 gtgccactag acagtgagtt agtgaaaaat ctattgggga catatcgcga tattactgga
    11581 gacatgactg aaccgtttgt atcaggcggc gctacttttg ctcgtacgat gaaccagtgt
    11641 gtggcattcg gtgcgatgtt ccctgatact cctgacttta tgcaccaggc gaatgaacga
    11701 tgggaattaa gtagtatgta taaagcaatg gaaatttatg cagaagctgt gtatcgttta
    11761 tgtgctaaat aaaaataaac atacaaaaag ggcggatatt caaatggata ttccgtcttt
    11821 ttttatttga tgctggaaag tttgcatttc tctcttattt ttttaaggta taatcatact
    11881 tgattaagaa aaaggggtca ctcagataga aaaggtggga gaaagtgaaa atatttagac
    11941 gaatactaat tggcttagtc atcattttag gattactcgg tggagccggt tattactata
    12001 tacagcaaaa tacgtacgaa ccatcgtcag aagcgcaagt gttggtaaaa gaaggaaaaa
    12061 acaaagaaga ttacttattt tttgaaggag agaaaaagaa tcatggaaag tctccattac
    12121 ttatttttta tcctggtgct ctcgtagagc cagaaagtta tagtatttgg gcgcaagatt
    12181 tagcaaaaaa cggcttttca gtcgctattg tcaaaatgcc acttgatcta gcagtgatgg
    12241 gcggaaacaa agcggataag gtcaaagaag attttccaaa ttccgattat gtgatcggtg
    12301 gccattcatt aggtggcgta atggcaagtc gttatgtcaa taagaatcat tcagacaaac
    12361 atttaaaagg ggtattcttc atggcaagtt atcccgacaa aaaaggaaca ttgacagaat
    12421 cagctgttcc tgttttatcg atcacggcga caaaagataa agtattgaat caggaagctt
    12481 atcaagaagc taagcagtat ttaccggaaa gaacagagta tgtatcaatc aatggcggaa
    12541 atcatggagg ttttggcagc tatggtgagc aaaaaggaga tggagaggca gaaatttcta
    12601 acgcagacca gcaaactgtg atcgtcaata cattggaaaa ctggctgaaa aagttgaaat
    12661 aatataaatg ggtcctatag ggtccgtgaa aaaactagtc aattaactat agatagcaaa
    12721 tgaatctttc aaaataagtc gggatttcac ggaacaagag aaacagatcc cggcttattt
    12781 tcaagtttag agaacttagt gtacgttttt aaagtttcgt ttatatttat attttatttt
    12841 ctaataaaat cgctcgaact ggacattttt gatacgcttt ttttacatat gtttcttctt
    12901 ccggcatcac gaactgttga tgagcctctg gttcttgggc aaataaaacg attccttctt
    12961 catcataatc gaaaatatct ggcgcttcga tttgacaaag accgcatgca atacagcgtt
    13021 caggtacaag tttacatagt agtgacattt ctaaccatcc taacttaagg agaataatat
    13081 gattgttttt attttatcgc tattttcatc aggacacaag ctgcggatta gttctcttta
    13141 ccaactcctt gtgggaaaac gaacgacttc agtacttatt tatggattta cccacgaact
    13201 tttgtttatc cataacagtt ttccagaatt gaagcaggat aagttttatc aaattttgca
    13261 aaaaattgcg cagcaaggtt ggatcgaaat aaatgaaaat gaagcaaagc taacgcctgc
    13321 aggggctgat atgttgtccg aacatcaaat agaacatact ggtttgcgtt ttgaccgcta
    13381 tggcagaaca ggggaaacta gttggcggct cattaaattt gctgttcaag taatttctaa
    13441 tctggcaacg ggtattcaag actatcttcc agcagagaca agtccttttt atactttcca
    13501 actaaaaaaa tggcttagtg aaagccaatt gccacgtgaa attttgattg atactgcgta
    13561 tgagagtttg gtgcagctgt tttcggagat accagaagaa gcagcagatt ttttagctaa
    13621 ccaattatct ggaaatgagc gaacagggct gcttccttat cagctggcaa aaaacaatga
    13681 tgagtcagcg gtttatctgc aacaaagcag atgtatccac cttttgttag cacaaatcga
    13741 aaaacggcca gattcgcttt ggcacgcttt gatcgattca ttattacagc aaaatttcaa
    13801 tcaaagcatg atgatcacca agcagatgtt tatgaatggt cagacaattg accagatcat
    13861 ggcaatccgt catttaaaaa gaggaacagt aacagatcat cttattgagt gggccttgtt
    13921 ttttgatgat tttccatacg agtggattct ctctgcagaa acaatcgaac gtttggaacc
    13981 aaataaggat tccgtgcgag agtggcgctt tagcgaatgg aatgtagatg gacaattaga
    14041 ttatggagaa tttcgtttgt atcaaatcta tctattgaga aaggaagcga tacagaatgt
    14101 taataaatga attaaaaaaa tattttggat ttgattcatt tcgtcccggc caagaagaaa
    14161 ttattcaggc gttgcttgat ggagaagata ctctcgctat tttgcctaca ggaacgggaa
    14221 aaagcctttg ctatcaattg acggggtatt taatggaagg tctggtcatc atcgtgtcac
    14281 cgctgctttc tctaatggaa gatcaagtga cgcaattaca aaaacgaggg gagaaacgag
    14341 tagctgcttt caatagttta ctttcgcaat ctgaaagaag atacgtcctc cgtcatctat
    14401 cgcaatataa atttttgttt ttgagtcccg aaatgttgac taatccttct cttttagagc
    14461 atctgaaaaa acaaaatatt gcgttatatg tagtagatga ggctcattgc gtgtctcaat
    14521 ggggagttga tttccgtcca gaatatcaac agttaggaaa aatccgaaag cttttaggaa
    14581 acccggtcac actggcacta acggcgacag caacagattt agtagcaaga gatatacgtc
    14641 atgtactatt tgatcgacca ccaaaagaga tcagacaatc agtcaatcgg caaaatatct
    14701 cgctttttgt tcggaaaacg cagcaaaaag aacaagaact tgaacacttc atggaaagag
    14761 cacaaggagc ggcaatcatt tattgtgcaa caaaaaaaga agtcgaacga ttgtatcatt
    14821 tattcaggga acgttttaca gttggatact atcacggtgg tcttgatgca gctcaaagaa
    14881 gacaacttca acagcagttt gtaaaaaatc agctgcagtt tctcattgct acgaatgcat
    14941 ttggtatggg gatcgataaa tctgatatcc gttatgtggt ccattatgat ttgccagaca
    15001 gtctagaaaa ctatgtacaa gaaatcggtc gagcaggcag agatcaggaa gaaagtgcag
    15061 caattctttt ttatcaaagt ggggatgaac gtatccatta tttctttaat caactttcta
    15121 gagaacagcg acaaagtttt gagctttatt tggaatatgc cacagagcaa gctccctttg
    15181 atgagctgca aaaaaaatgg atggagctga tccagcagtc tgaaaaacca gaaaattggg
    15241 tggaacggct caaacgtcag gaaaaagaaa aagaattccg cctgcagcag atgcttcgct
    15301 atattaatga agaaaactgc cgcagaaaat tcatcttagc ttattttggc gaaaaactct
    15361 ccgaaaagcc gcagaattgt tgtgatattg atggagcaaa agcagaactt ctgccaaaga
    15421 ggaagctttt ttctaagact gaacaacttc attgggaaac gattttacta aatttattta
    15481 aaaaaaacat ggaacattga ttttttagga caagacactt tttcctatgg tataatacac
    15541 acgatagagt ttaggaggta aaacagtgag cagaaaagat agacatcaat ctacagaaaa
    15601 taacgaaaca caagaaccat gggaacaacc aatctacgat acagatgatg aagtttcatc
    15661 aagaagttct cagagacaac aaaagaaagg aaatacatta tttctttcgc tatttttgat
    15721 tttactggtc ttatgtatcg ctattccagc aggtgcttat ttctggatca gaaatggatc
    15781 aagcaacaat gcaacagcag caacttcttc tgaaacttcg acatcagtag tagaaagttc
    15841 tacaagtaca acaaaagagg agtcaactga gacttcaaca gtagaatcta gtacaatcgc
    15901 ggaagaatct actgtgtctc aagatacagg tgtaacgtca gaaagcagta ttgcagcaga
    15961 gacaacaccg acttcctcaa gtgaggcaac ttatcaagca ggggattcaa gcagcaatgc
    16021 agcagaaaca acaccttctt catcagctgc agccggttca acaacgactg ttcaagcagg
    16081 cgaaggtcca aaacaagtgg ctgagcgtgc agggatcacc actgatcaat tgtttgaatt
    16141 gaatggctta gatccaaaca actttatgct ttaccctggt caagaattaa gaattaaata
    16201 ataatagccg cgctttgcgg ctttttttct gagaaaaagg agttatatca tgacacaaat
    16261 cagtattgca atcgacgggc ctgcttcatc tgggaaaagt accgttgcca agatattagc
    16321 aaaagaattg aattatattt atacagatac cggtgccatg tatcgcgcag taacttattt
    16381 agctattacg aacaatgtat ctttttcaga tgaagaaggg ctagtttcgc tgatcaaaaa
    16441 gtatcctatc tctttttcgc aacaagaaga tggacagcat gtattcatag catcaaaaga
    16501 tgtgacttta gaaatccgtc aaccagatgt cacaaaagct gtttctgaag tctctgcaca
    16561 tggaaaagtc agagaagaat tagttgctgt ccaacgaaaa ataggggaac gcggtggcgt
    16621 tgtcatggac ggaagagaca tcgggacagc tgtattaccg aatgcagaag tgaaaatctt
    16681 tttagtagca agcgtaagtg agcgtgcaga aagacgtttc aaagagaacc aagaaaaagg
    16741 aattccgact gatcttgaaa cactgacgaa agagatacag gaaagagacc attatgattc
    16801 aacaagggac gtctctccgc tgaagcaagc agaggatgct gttcgtatcg atacgactgg
    16861 caaatcgatt ccagaagtcg ttgcagcaat aaaagctgtt gttttgaaaa aaggttatct
    16921 tcttttttaa attaagaaaa aaaatgaaaa acaattgttt tttcaaggaa aacgaacgaa
    16981 atcgctttat tttttttgaa taatcaatta aactaaaaac agtaccgtac ttacggcaga
    17041 atgttggtta ggaggacaag tgttatgaca gaatttgatc aaaatcaaga gaacaaccag
    17101 tcaatggaag acgcaatgaa aagcgtacaa gaagtaaaag ttggcgatgt tgttaagggc
    17161 gaagttttag tcattgaaga caaacaagtg attgtcggaa tcgaaggggc tggagttgaa
    17221 ggagtcgttc cggcaaaaga attatcaact ttgccggtag aagatatcag cgaagtagta
    17281 aaagtcggtg atgtattaga tttagtcgtt atcagtacga tcggcaaaga taaagaaaac
    17341 ggcagctatc tactttcaaa acgccgttta gatgctaaaa aagtttggga agatatcgaa
    17401 agagatttcc aagagggcaa ggtcatcgaa gcacctgtta caaatgttgt caaaggcggt
    17461 ttagtcgttg acgtcggtgt acgtggtttt gtccctgcat caatggtgga agatcatttt
    17521 gttgcagact tttcagacta taaaggcaaa acattgagct ttaaaatcat cgaaatcgaa
    17581 ccatcagaaa atcgtttgat cttatcgcat aaagcggtag tggaaaacga aagagaagaa
    17641 aagaaaaaag aaattctttc aactatccat gagggagatg ttctcagtgg acgtgttgca
    17701 cgtcttactg attttggcgc atttgtcgac ctaggcggaa ttgacggtct agtccatgtc
    17761 tcagagattt cacatagtca tgtagcaaaa ccaagtgatg tattggctgt caatgatgat
    17821 gtaaatgtca aagtgttgtc tatcaatcct gaacaagaac gtgtttcctt gtcaatcaaa
    17881 gacacacagc ctggaccttg gtcagaaatc gatacaaaag ctccagttgg cacagtatta
    17941 gacggaacag ttaaacgttt gacaagcttc ggtgcctttg ttgaagtgtt ccctggagta
    18001 gaagggctag tccatatctc tcaaatttca cataaacata ttgcgacacc acatgaagtg
    18061 cttcatgaag gtgacgaagt gaaagtgaaa gtattagaga tccatccaga agaacatcgt
    18121 attgcattga gtatcaaagc tttagaagaa aaaccagctt cagaagaaga accaaaaaat
    18181 gttgagtctt atgaattacc agaagaaaat actggattta ctatgggaga cattttaggt
    18241 gatgcgttga aagaagaagt agaagaaaaa gcaaccgatg attctgaaaa ataattgatt
    18301 ttgtatctgt gactgagatg aaagcagctg cttttgtctc agtttttctt ttgaaaagcg
    18361 attagtattt caataaggaa taaaaatact tcgtttaatt gacaatctat gcttgaaagt
    18421 tggcaatgca ttcgttaaac taagtgagat tggaaacttg tgaggaggaa ataatatggc
    18481 aaatccaaca attgcaatcg ttggccgccc gaacgtcggt aagtctacga tttttaaccg
    18541 catcgctggt gagcgtatct cgattgtcga agatactcct ggagtaactc gtgatcgtat
    18601 ttatgcaaaa ggtgaatggt taggtcgaga attcagcgtg atcgacacag gcggaattga
    18661 tcttggcgat gaacctttta tggatcagat caagcatcaa gcagaaatcg cgattgaaga
    18721 agcagatgta atcatttgtg tagtcagcgg acgcgaaggc gtgacagacg cagatgagat
    18781 ggttgcgaaa attttataca gaagtaataa accagtgatt ttagcagtca ataaagtaga
    18841 taatccagaa atgagaaacg atatctatga attttattcc ttagggctag gcgatcctta
    18901 tcctgtttca ggaagccatg gactagggat tggtgatatt ttagatgaag cagtgaagta
    18961 tttctctgaa gagactgaag aagaggacga cgacacgatt aagtttagtt tgattggtcg
    19021 cccaaatgtt ggtaaatcct ctttgatcaa tgcgatttta ggagaagaac gtgtaattgt
    19081 ttcggatatt gaaggaacga cccgagacgc aatcgacacc cacttcgttt ctgaaagtgg
    19141 tcagaaattc ttaatgatag atacagctgg tatgcgtaaa cgcggaaaag tatacgaaaa
    19201 tactgaaaaa tacagcgtga tgcgtgcaat gcgtgccatt gaccgttctg atatcgtttt
    19261 gatggtactg aatgctgaag aagggattcg ggaacaagac aagcgagtag cgggttacgc
    19321 ccatgaagct ggtcgtggaa ttattatcgt cgtgaataaa tgggatcttg taaagaaaga
    19381 aaccaataca atgcgtgatt tcgaacaaga gattcgtgat gaattccggt atcttgatta
    19441 cgctccaatc gtttttgttt ctgcagtgac taaacaacgg ttggaacgtc tgcctgaaat
    19501 gatcgaacaa gtaagtatga accagaatct tcgtatctct tcggctgtgt tgaatgatat
    19561 cattatggat gctgtagcaa tcaatccaac accaacagat aaaggaaaac gcctgaagat
    19621 tttttatgct acacaagtcg ctgtcaaacc acctacattt gtcgtttttg tcaatgaaga
    19681 ggaattgatg catttttctt atgaacgttt cttagaaaat caaatcagaa aagcatttac
    19741 ttttgaaggg acgtccatcc gaattatccc tcgtaggaga aaataggcat tttaccatat
    19801 cgacgttttt ttttcaaaag aaaaagacag tttcgtttgt tacgtttcta tgactaaaaa
    19861 aagcatgtga aaattggtaa aaaccttgct attaagcggt tcatatgata tcgtgataac
    19921 agaatattga agttaatcaa tatttctttt taaacttctg gaccactcag aaagttttaa
    19981 ctaaatgata tttctatcat atctcttgtg gaggaggtga atctatccat ggcaaacaaa
    20041 gcagaattaa tcgaaaaagt tgcttcagct actgatttaa ctaaaaaaga tgcaactgca
    20101 gcagtagatg ctgtattttc aactattcaa gatgctttag ctaacggcga aaaagttcaa
    20161 ttaatcggtt ttggtaactt tgaagttcgc gaacgcgcag ctcgcaaagg tcgtaaccca
    20221 caaactggtg aagaaatcga aattccagct agcaaagtac ctgcattcaa accaggtaaa
    20281 gcattaaaag acgctgttaa ataagacagt tgaaaaagcg cttgtggctc tagggctaca
    20341 agtgcttttc tttttatttc ctagcagaaa aggaataaat aagagacaga gattccgaat
    20401 ccgtatgtca tacatagaaa acacatgtat tttatttaat ttttatttat ttgcaagtta
    20461 tgaggtgagc tttgctctta tcttttctag aatttgctta ctaatggtaa aataaaaata
    20521 agaagaggag ggatgcgtat ggaacttgat tatcaagtag aagatgcgtt gacgaaagtg
    20581 ttttacggag aaacgctagt cagtcagcta agagaacttt ccattgatca gccaatctta
    20641 tttttaacga atcagcgcta ttatgatttg tttgcagata agatcaaccc gttatttgca
    20701 aatcaagcaa acaatgactg gtatatttgt gccaacactc aatgcaatca tttaacagaa
    20761 ttaaagaacc tgcttgattt cgtcaaacgc tatcccgaaa atcaatccat gtttatcatc
    20821 ggatttggaa atgaagggat catggatctg gcaggttttt ttcaaaaaca tacaaccctt
    20881 gattcatcac tatggatgat ccctgtatcg atccgttctc taagccgagc attaacaccg
    20941 cagcggacga ttttgcagct accaaatcgt gtagtgctgc aaaccatcaa tctgccagaa
    21001 cgcatcgttt atgatcaaac aatcagcgag cggcaggtgg acggaaagca gattgacttt
    21061 ttgactttta tctgttgcgg aatgatttgt gatcatcgtt ttttgcaaaa tctgtataaa
    21121 aactatccaa ataaaaagca attaacgact cggccgtttg ccgggatgat cgaagaaatg
    21181 atctattttt atcaattaga ggcagaaaac ctgtcaaatt atggtaaact gtttgaacaa
    21241 gctttttatc tgaccgaaaa tggccatcta ctttctgcta gtatgaaaaa atttttagga
    21301 atgatgtttc atttcgtgtg gaatctccaa gcatatcctt ttgatttcca actaaaaaac
    21361 ttttttgtgt ggctggactt gcttggctat ccaatccact ggctggaaca gatttcaaag
    21421 atggagtatt tggaaaaagt tctttttttg gcagaaaaaa gcaaaaaaat acttgtttta
    21481 gaaaaaatag gtataataga cggataccaa catccaaacg aaaaagaatt attgagaaca
    21541 atgacggtat ttcaacaaat cgtcagtgag ataagaggga attgaaatga atacaaatag
    21601 cgaaaaaatg ttgcaagctt tatcagatga agacttgtca caagcacaaa tctttttaga
    21661 aaaagcatta aaagaagacc cagcagatat attagctgaa ctaggcgaag aattgctggc
    21721 tattggcttt ttgatcgaag caaaacagat ttttgaacaa ctgatcaacc aatacccaga
    21781 aaatgacgga ctgaacatcc cgttagcaga aattgcaatc gaagataatg agatcgactt
    21841 agcttttgaa tacctggaaa aagtggataa gcaaagtgat tactatccgc aaagcttatt
    21901 ggcgatagct gatttgtacc aagttatcgg aatccctgaa gtgagtgaag caaaattgaa
    21961 agaagcagct gggttgcttc ctgatgaacc attgatccag tttgcgctag ctgaattgta
    22021 tttttcagtt gatcgtttca aagaggcagc agtggtttat gaaacattgt tggcaagcgg
    22081 gataaatgaa atttcaggaa tctcgatgca ggaacgttta ggacaatcct taagtatgca
    22141 aggagaattc gaagcagcta tcgtaccttt agaagaagca ctgaaagaag aaaggacaga
    22201 tgatcgactg ttccagctag cttttacgaa tcttcaattg aaagaaaatc agcaggcaat
    22261 caactatctg gaagaacttc gagaagttaa tccgcattat caatcgttat atctatatct
    22321 aggacaagct cttcaagaag aagaaatgat tgaagaagca caaacagtgt tagaagaagg
    22381 aatcaaagaa aatccttacc aagtcgaact ttatcacctg gcctcggaaa atgctttccg
    22441 tctgcatgat agacagcgag cagaagaact tttactgaaa gctttagaag taggagacaa
    22501 acaagatgaa acattactta ctttaagtaa tctttacttg gatgatgaaa gatatgaaga
    22561 tgtgatacaa gtgatcaatc agatggaaga aactgctaat ccttatgcag aatggaacct
    22621 agcccatgct tataatgaat tagaagactt taccgttgca gctgtacact atgaacaggc
    22681 ttatcatgaa ctatcacatg aaccagattt cttgaaagag tatgcctttt tcttaagaga
    22741 agaagggcag ctgaaaagag cgcaagaatt attgacttat tatttaacac ttgaaccagg
    22801 agatatggag gcactgtcat tattagatga cctaacagag aggtgagaaa aatgctaatt
    22861 gatgtacggg aaaagaagaa ttttttaacg tggatggtca atcatgtatc ttttagccga
    22921 agagaagttt tttggatctt gaattatctt gccaatcatg aagcgatttt aagcaatgtc
    22981 cactttgttg aaggggcgaa ttttgcggat cgaggactgc agatcagtga tctatctgtt
    23041 gaaggggaac ccatgaaatt gtttttgcag ggaaaagaat ttacggacac agaccagatt
    23101 tttcatgaaa tccgtttgaa ttggaaaaag cctttatatg tggaatgtat attcgaaaat
    23161 gcttggcaga caagagaata tctatctatc ttagaagaca atccattttc ttcttgggat
    23221 tcttcagtca gtgaagaaga tactgaatta attgaacgat attttcaaga aaaagaagaa
    23281 gaggcaaaac taaaaatgct ttatgctcaa atcgatcaag cactagaaga tggagatagg
    23341 gatgcttttt tgaaattatc tgatgaagtt aaccgaaaga tccttttgca gacacaaaag
    23401 aaaagtaacc gggtaagtga acataacaat tagttaaaaa tagtatagta ctaaaaaaga
    23461 caaaggtcag ctggatgtgg aatctttcct catagcctat ctttgtcttt tttcttatag
    23521 ttttttcagt aatcttgtct gtggcttcaa ataagtaaag ccttgccctt ccacttcatg
    23581 cacattgatg attgaaagga aagctttttc gtcaatctcg tggacgatcc tcttagcttc
    23641 agttaattca ctagagctaa cgaccatata gatgattttt tttgaattac cagagaatgc
    23701 gccttctcca gaaaggaaag tcacacctct ttgcagaccg gtcatcagta gtggtgcaat
    23761 ctcttcgctt ttgttggaga cgacaagtag accttttgca gaatatccgc catctaagat
    23821 cgaatcaatc acacgactga aaacatacga aacaatcaac gtatacatca tacgtttcaa
    23881 gtcgatatag gttaatgaag caagtaagac gatgatatca aatgccaata gggaacgccc
    23941 catagtgatg ccgtaatttt gttctaaaat ccgagcgata atatcactgc cgcctgttgt
    24001 tccacccatg cggtagacga tcccgcttcc tacacctgca actaaacccg caagtagaga
    24061 aacgatcagt agatcatgct gtaaattgat ttctagtgga accctttgcc agatccataa
    24121 aaagaatgac aaagaaagtg tacctagaac agtataggcc aaggaacgtt taccgaggat
    24181 ctttcctcct agtaaaatca atgggatgtt gattaataaa gtcgtataag ctggatcaat
    24241 accaaataaa gctcttaaga tcaaggtgat ccctgagact cccccttctg ctaaatgatt
    24301 agcgatgttc aagtaaacaa gaccaaatgc ataaatactt gttcctataa tgataaaaag
    24361 aacttctttt actgtttttc gtttgaccat atgaattcca gctttcaatt atgtattttc
    24421 acagaatttc catttagaaa ttccttccta aatgtagcat ggaaattcga ttttctcaat
    24481 tgctcttatc taggatttgc gttaaagttt tggtaagata gttttggagg gaaaaagatg
    24541 gataaaaagc gttctttata cagtatgcag caggaagtgg atgaatatat ccagcaattc
    24601 aaggtggggt atttctctcc attagctcag atggctcgat taactgaaga agtaggtgaa
    24661 ttggcaagag aagtcaacca cacttatgga gaaaaaagca aaaaggcttc tgaaccagtt
    24721 aactcggtag cagaagaact tggtgatgtt ttattcgtta cgatgatcat ggctaattca
    24781 ttgaatatcg acttaactga agtttttgaa aaaaacatgg aaaaattcaa tcaaagagac
    24841 cataatcgct ttgagcgtaa ggacgagtaa acaagatgaa gtggtcctgg ccttgaagac
    24901 tctgaaacgg acttgtcaaa cagtcaccat gcaactgagt ctttatctca ggacaagaaa
    24961 cacgcaggaa aggttggaaa aatgaaatta aaacaattac ctctggaata ccaaaaggca
    25021 attccagttc tgaaaaaatt agagaatgca ggatatgaag cttattttgt aggtggaagt
    25081 gttcgtgata tcttgctgaa ccagccaatc catgatgtgg atatcgcaac aagcgcattt
    25141 ccagaagaaa tcaaacagct ttttccaaaa acgatagata ttgggatcga acatggaact
    25201 gtgttggtat tagaaaatga tgaacaatat gagatcacca catttcggac ggaatcaact
    25261 tatcaggact accgtagacc agatcatgtc gaattcgttc gttcgttggc agaagatttg
    25321 aaaagaagag attttacgat caatgcgttt gctttgaaag aagatggaga aatcatcgat
    25381 ttgttcgatg gtctgcaaga tctagaagaa cagatcttgc gagctgtagg caatcctcat
    25441 gagcggttcc atgaagatgc cttacgaatg atgcgcgggt tgcgttttgt cagtcaacta
    25501 gggttcaaat tagaggaaga aaccttctac gccatcaaag aaaaccacga gctattaggt
    25561 aaaatatctg tagaacgtat aaatgtggaa ttcatcaaga tgctcttggg aaatgaacgg
    25621 gccgcgggaa tccatgcatt tattgaaaca gagtgctaca tttgctgtcc cggtttgaaa
    25681 gaagaaggcg aagcactttt acgttttgct gaattaccat ccgtcccatt gaaagaagag
    25741 agccaagcat gggcattatt gatcagccaa ctggatctaa aagaaaatga gattcgttcc
    25801 tttttgaaat cgtggaagtg ttctaaccaa atgattaaag acgttcaagc acttgtccaa
    25861 ggactacgac aacgagaaac tggagctttg gaaccattcg aattgtactt cttaggcaaa
    25921 aaacatgcac tgcaagtaga agaattgatg atctattttg acgaaacacc tcagatggat
    25981 gccgtaggag aatcctatga tcgtttacct atcaagtcat taagcgaatt agcagtagat
    26041 ggtaaaatct tgctagaaga aactggaaaa aaacctggta agtgggttag tgaagctttg
    26101 caattagctg aaaaagccgt cgtagaacaa agaataaaaa atgataaaaa acaggttttg
    26161 gattttttat cgaaagaaaa attgatttaa aaaacactag actgtatctg ctcagctttg
    26221 ttggctactt aaagtgggca gatacgtcat tagaagaaaa aacataagat gtgaccactt
    26281 acataaattt gtgctaaact gaggtagtac aagaataaat tacatcataa aggagtcttt
    26341 ttaatgagta aagaaatgac agcgctaaaa ttttatttta gaaatggaga aacctggacg
    26401 atcaaccgcc gtcatatcgg cgatctttgg atcaaacaaa tcacaacaag ttttggacga
    26461 atcaatggca gtgaatttgt tgaaatccat ccgtgtgctg gatttaaaat cgaaatcttc
    26521 catgaagggg acgcagttgc gacacatgat atcaacctag gcggactgga aatgggcatg
    26581 tttaatcgcg cattgaaata cgaagatatc gagcgaatgg aaatccttta ccgaaatggc
    26641 acacctgatc ttgtgtactt cccatatcta gataaaggaa cagaaggatt agacaatcaa
    26701 tatcaatcaa caaaaatcag cgaaaaaaca ggtaacttgt atatcgtgat caatccagat
    26761 caacgtgtag aagatgtata cggggaattt ttcgaataaa tcgattttta cgcaaaaatg
    26821 aggctgtgaa agagatgtgt cttattacta ctgataggct gtctcttcca caccgtttat
    26881 tcagaataag ggactgtgac aagatttttg tcgcagcccc atttttttgt tgtgataaaa
    26941 gaacaagaaa ggcaggaatg ggaaagtaaa catccttttg tcagaaactt ttatctttct
    27001 taagttttac ttgatatctg atactatttg gaatagaatg aggcgttgaa aaatttatgg
    27061 aaatttctaa ctagcaataa acgatgaaac aatgaaatat ttttcatcca aaaagaactt
    27121 tgctataatg atggaagttt gtgtatagga gatctggaaa atgagagaga gttttgaaca
    27181 acaaaaaaaa ctgttgcatg atcgctatgg cgccctttcg atggatgacc gccgtcaaat
    27241 actttgtaag ttgcgtaaaa gaaatatatt gatgtatcgt cagttggaac gtctgaaaca
    27301 tgatctgctt cgtttggagt caaaacgtgt acagtgtgaa ttagagggga accaaacaca
    27361 ggttgaagta gtcgaaacca aaattttaaa gaaaaaagaa caatttttaa aaatgcttac
    27421 acaaaataaa aaataaaggg gatggacgat ggaatttgct gagttagtta ttgtatttgc
    27481 agtaacgatc accttatcga acatagctag ccgcattttg ccaatgattc cagctccact
    27541 gatccaaatt ttccttggag tggtattagg tctgacagag tggggacaat caatcgattt
    27601 tgaacctgaa ttgttcttag ttatgattat tgcaccattg ttatttagag aaggagaaaa
    27661 agcagatatt tcttcgattc tcaaaaattt cgggacaatt ttgttcttgg catttggagg
    27721 agtcattttg acccttgtcg gggtaggtgc gacgttatca ttcctgttgc caagtgtccc
    27781 acttgctgcc tgctttgctt ttggagcagc gttaggtccg acagatgcgg tagcagtcag
    27841 ttctctttct ggacgagtga atatccctaa aaaggcgatg catattttgg aaggagaagg
    27901 tcttttgaat gatgcatctg gtgttactgc cttccagttt gctcttggtg cgctgatcac
    27961 cggatctttt tcagcagtaa acgcggggat gagtctagta gtttctagta ttgggggagc
    28021 tttgatcggc tttttgcttg tctggttcaa acaaaaaata attcatttga tcgaaaaagc
    28081 atcagcacaa gatgtcacag ggtatctgct gatcgaactt ttgcttcctt ttctagccta
    28141 tgtattggca gaggcatttg atgtatctgg aatcattgct gcagtggcag caggtattct
    28201 ccaagcttct ggttttagga aaatctctgt gtttgatgca gaattgtcga gcttgtccca
    28261 cagtacatgg acaactattg cttttacact gaatgcatta gtatttatat ttttaggaat
    28321 cgaattgacg caagtgttct cgccagtatg gggagacggt ttatatccaa acggtctttt
    28381 attagcgatt atcgtattaa tctctgtcat gctttttgtg atcagattca tttctatcag
    28441 tcttttttat gtattcaaag atggcagtaa aaagttcaaa aaacagttga acgagatctt
    28501 gatcttaaca tttggcggtg taaagggaac agtcagtttg gctacgattt ttattttgcc
    28561 attttcaatc aataatatga tgttttacca gcggtctttg cttttgtttc tgacggcggg
    28621 tgtcatctta gtgactttgg tcatagggat cattgtcttg cctatgctga cggaaacaga
    28681 ggaagcgaaa agcacggatt tgaatgcttt gatgatttta gaagaggtcg ttgaagtttt
    28741 gcgaaaagaa ataaaggaaa ttgatcgtaa tacaaaagaa tttttagcca ctgaagcagt
    28801 gatagaaaat tatcaagaac ggatacgtga tctgtacttg gaagatttaa ccgatgatga
    28861 aaagcaagaa gtacaagaaa tacaagcact gattttgtcg atcgaacggg atggattgga
    28921 tgaaagttat cgttcgggca agctttcttc taatggttat cgtttttact cccgttttct
    28981 ttctcgattc gaacattcta tcacaagcca gattttgtct tttatcggct tttggttcat
    29041 tgttgtccgt aggttaatgc gaatcgttct ccatccgaaa atgttttggc aaagaagata
    29101 tgctgatcgt cagacattta ttagtgatga agatatccaa gaaatcagag agacatatca
    29161 aaaaaatact cagttgatta ttgaaagttt agataacttg actgatattt atgatgaaac
    29221 gatggttcaa ttttttatcc agcaacgcaa acttgaagga ataaaaatga actcggggaa
    29281 tttgatttct tcgtggatga tccagcaaga tagtctgttt acgaaaaaaa tgctaagagg
    29341 ttattatctt gaaagaaaaa tcattgatga atacgaagtt gctgaaaaaa tcacgacgtt
    29401 ttctgcgaac agctatcgca ggaatatcaa tttgttagaa tcttatacga tgaacaaacc
    29461 atctgataac ttttctttcc gatttgcgtt tcgagcaaag tcaaaaaaaa cgagtccaat
    29521 aaaataaaaa ggtaaaaatt ttcaagtttt ataaaaaaca aaacatatca gaacaggatc
    29581 gaatcggtcc tgttcttttt ttgagaacac aaaaagaaca aataccaaaa aaattttcct
    29641 gaagttcact atttttatga tacaatatcc aagataagga gggaacatgt tgaaagaatt
    29701 aaaagtaact gacctcaaaa aaacttatgg tgaaaaagat ttgtttgacc agatttcttt
    29761 tttggtccac gaaaaagacc gtatcgggtt gattgggacg aacgggacgg gtaaaacaag
    29821 tctcttaaat attattgccg gtatcgatag cagcgacggt gatcggcaaa cagtgtttta
    29881 tccaactgat taccgtattg gttatctttc tcaagcagct gaattttccg atgaattaac
    29941 tgttctccaa gcagtctttc aaggaaacag ccccttgatc caaactgttc gagcatatga
    30001 ggaagcattg atcgaactag gggaaaacgg agaagaccct gatgtgcaaa aacgttatgc
    30061 taaagcagaa gaacaaatga ataaagaaga tgcttggact acagatacca acgcaaagat
    30121 tattttgcaa aaattaggaa tcagtgaatt agataaaaaa atcagtactt tatcaggtgg
    30181 tcagaaaaaa cgagttagtc tggcgcaagt gttgattgat gaacccgatt tactattact
    30241 agacgaacca acaaaccatt tagattatga agcgatcgag tggttggaaa actatttgaa
    30301 acaataccgt ggcgcactat tgatggttac ccacgatcgt tattttctag atagagtagc
    30361 aaaccgaatc ttcgaacttt catttggaaa attatacgag tataaaggaa attatgaagc
    30421 ttacgtctta gaaaaagcag aacgtgatcg tgtagaagta gaacaagaag aaaagcgcaa
    30481 gcggctttat aaacaggaat tagcttggat gagggctggc gtacaggcac gtggcaccaa
    30541 gcagcaagca cggatcaacc gtttcgaaga tctaaaggag aacttgtacc aagtaaacca
    30601 agaagatgat ttagagctga acctagcgac acaacgttta gggaaaaaag tactggaaat
    30661 caaagatggc agttaccgta taaatgacca aacactgcta gaacatttag atttattgat
    30721 tcaatctcgg gaaagactag gtattactgg taaaaatggt gcgggaaaat cgacattgct
    30781 taatattcta gctggcagaa ttcccctgga tagcggtaca atgtctatcg gtgaaacggt
    30841 tcatcttgcg tattatacac aagaaaatga agaaatggca ccagataaac ggatgattgc
    30901 ttacttacaa gaagctgctg aagaagcaaa aacagcagat ggcagtcaaa tcggagtagc
    30961 agaattactt gaacgatttt tatttccaag atttatgcat gggacactga taggcaaact
    31021 ttcaggcgga gaaaaacgcc ggttattttt gttgaaactg ctgattcagc aacctaatgt
    31081 tttattattg gatgaaccga ccaatgattt ggacatagca acattgacga ttttggaaga
    31141 ttattttaga agttttccag gtgctgtgat cactgtttcc catgaccgtt atttcttgga
    31201 caaggtagca gataagttat tagtattcca aggaaacgga aaacaagaac tttattacgg
    31261 aaacatgtcc agttatttac tgaagcaaaa agagacccag cagcctgctg aaaaagcgaa
    31321 accaaaaata cagagcaagg aacctgctga aaagaagaaa ttatcttaca tggaacaaaa
    31381 agaatgggaa acgattgaag atgagattgc agaacttgaa gaaaaaatct cattgctcca
    31441 agaagagatg aatcatcaag gagataattt cactcgatta caagaattgc aaaacgacgt
    31501 atctgaaaca gaagcacaac ttgaagaaaa aatggcacgg tgggaatact tgagtgaatg
    31561 ggtagaagat taggaggaaa aaggatggaa caagcgtatc ttgacttagg aagaaaattg
    31621 ttggaagaag ggcatcgtaa agaagacaga acaggcacag gcacattaag cttattcgga
    31681 taccaaatgc ggtttgatct gcaaaaaggg tttcctttgt taacaacgaa acgagtacct
    31741 tttggattga tcaaaagcga attgctttgg tttttaaaag gagatacgaa tatccgctat
    31801 ctattacaaa ataaaaacca tatttgggat gaatgggcat ttgaacgcta catcaaaagt
    31861 ccagactata atggaccaga tatgactgat tttggccata gatgtttgac agatcctgaa
    31921 ttcaatgaag aatataaaaa gcagagcaag cttttttgcg agaagatcct aaccgatgat
    31981 tcctttgctg aaacatacgg cgatcttgga cacatctacg gctatcaatg gcgtcactgg
    32041 gaaacaaaag acggtggctt tatcgatcaa atcaaacaag tgatcgaagc aatcaaaaag
    32101 actcctgatt ctagaagatt gatcgtttct gcatggaatc cggaagatgt tcctagcatg
    32161 gctttgcctc cttgtcatac gatgtttcaa ttttatgttc aagagggacg gctaagctgc
    32221 caattgtatc aacgcagtgg ggatgtgttt ctaggcgttc cgttcaacat tgcaagttat
    32281 gcgttgctga ctcacctaat tgcacatgaa acaggtttag cggttggcga atttgttcac
    32341 acattaggag atgctcatct ttatatcaat catatcgaac aaatgaaaga acaattgagc
    32401 cgagaaatac gcgcatttcc gactttagtt ttgaatcagg aaaagcagtc agtatttgat
    32461 tttgagatgg aagatatcca attagaagga tatgacccac atccggcgat caaagctcct
    32521 atcgctgttt agaatcagaa aggatgagaa aatgttagct gcaatttggg cacaggatga
    32581 aaacggattg attggaaaag aagaccgtct tccttggcgt ttgccaaatg atctgaaatt
    32641 cttcaaacaa atgacagaag caaatacact agtgatggga cgaaaaacat tcgaagggat
    32701 gggtagccgt ccgttgccga atcgtcagac gattgttttg acgagagatt cttcctataa
    32761 agcagaaggc gtgcatgtca tgcatagtgt ggaagacgtg cttgctctgg aaaaagaaac
    32821 agacggtatc tttttcatcg ctggagggtc agctgtttat caagaatttc tgccattttg
    32881 tacgatatta taccgtacag tcatccatca tgtattcgat ggagatgctt attttccacc
    32941 tgttgactgg tctgattggt cactgatcaa tactagtcaa ggagaaatgg atgaaaaaaa
    33001 tcgttatccg catcaatttg aaacgtatca gcgtaatgag aatcctgtaa aaagcgggac
    33061 aggcgaattg acgatataaa aaagctatgg atagactagc tgttatttag agctgtccca
    33121 tccatagctt tatttttttt attaagtaaa gaataaaaca gagaagtaca taaaacctgc
    33181 acctaacata acaaacaaat gccaaacaac atgcatatag cggatagaat tcaagctata
    33241 aaagaatgcg cctatcgtgt aagaaagccc gcctgctacc atcaaaataa caccagtcat
    33301 tccaagagag tgataaagag gaacagcagc cacgacacag agccacccca taaaaatata
    33361 gatgatcgta gatacttttg atactctctc ccgtttatgc aacgtcaacg ctttatatat
    33421 aatgccaaga atcgcaaaca accagattaa tacaaataaa gtccaaccta gccatcctcg
    33481 gatactcagc aaacaaaaag gagtataact tcctgcaatc aaaagaaaaa tcgaactatg
    33541 atcgaatact tggaacacct tttttgcttt tgtaaaaatc aatgaatgaa acaaagtaga
    33601 cgttaaaaat aaaagaatca tcatcgatcc atagatagca taagagacaa tatggaggga
    33661 ggaatgcaag tgggcacctt ttactaaaag aaccactagt cccgcgatac tcaatccagt
    33721 cccaattcca tgggtgactg cattaaacac ttcatttaat atttcatacg ttcgattaaa
    33781 tttcgttttt tccatgaaaa cggctccttt actaggtgta attaatgaaa aatcattatt
    33841 tgtctgttat actaaaaata gaaattgtct tacatgtagt ttaacatgaa taaggcatct
    33901 tgttaaagaa agagagagag aaaataatga caaatgtaaa aatcgtaaca gattcttcat
    33961 gtacgatgga aaaaaatgta cgcgatgctt taggcattcg tgtcatgccg ctatccatca
    34021 tgatcgacgg aacagtatat cccgatgatg accaactaga cggcgaaaga tttatggaaa
    34081 tgatggcgaa agcaaaaaat ctgcccaaaa caagccaacc accaattgga gaattcatct
    34141 cgatgtatga tgagctagga gaagacggca gtgaagtgat ttcgatccat atgacaaaag
    34201 gcttgagtgg aacagtagaa gcagcaagac aagccagtaa tctaacaaaa acgaaagtaa
    34261 cggttatcga cagtgatacc actgaccaag gattatcttt tcaggtaatt cgagcagctg
    34321 aattagcaaa agaaggtaaa acagtagaga aaatccttga agaagtcaaa aaagtacaag
    34381 acaatacaaa attatacatc ggaatatcca cactagataa cttggtaaaa ggtggaagaa
    34441 tcagccgaac aactggtttg ctgtctagtg ttttgaacat acgcgtggtg atgaatttcg
    34501 cccattctga attaatccct gtaactaagg ggcgaggaaa gaaaacgttc gataaatggt
    34561 ttaataattt gaaaaatgaa ctgaaagaat tgccaaatgt gcgacaaatc ggtatttcac
    34621 atgcggatgc aaaagaattg gcgcaagaat tcaaagaggg tttgcaagaa ttattcccgg
    34681 acatgcatat ccctgtactg catacgaatc cggttatcgc tacgcatact ggtaaagacg
    34741 cgtttgcaat catgtattat gtagattagt cgaaaagagg ataagccctc agcctgaaag
    34801 gcttgcagct tattctcttt ttctttataa aattaggaaa ataattgttt tcttttttca
    34861 taaagactac ctttttgata aaatttttga taacattaga accaatcgaa tacaagaggt
    34921 gaaaaaatga aattaacgaa acgacatttg atcctcgttt tgttcccatt attaattgcg
    34981 atcatcatct atgcaggttt agctgcttct ataccgaaag ctggcccact aatgaaacca
    35041 gtaactactg tgagagaaga tccaaataaa aaagaaaaac ttcactacat agctatcgga
    35101 gattcgctga ctgaaggagt aggagatcaa accaagcaag gaggattcgt tccccttgtc
    35161 gcaaatgatc taaaagaccg ttataatttg accgcggttg aaacagaaaa ctatggtgta
    35221 aatggtgaac gaagtgacca gatcttaaag cgagtaaaaa caaaagaaga aattcgaaac
    35281 aatatcaaaa cagctgattt tatcacactg actgttggcg gtaatgattt gatgaaagtt
    35341 atccaaaata atttattcgg gttaacggtc aattccttta aaaagccact gaaaaactat
    35401 caggaaaatg tcacagaact attggaagaa tttcgatccc tcaataaaac cgcacctatt
    35461 tacattttag gcatctacaa tccattttat ttgaactttc ctgagatcac tgacatgcag
    35521 acaattgtta acaattggaa caaaggaaca gaaacggtga caaaaaaaat gccgaactgc
    35581 tactttatcc caatcaatga tttgctttat caaggattga atcaggaagt aggtgtcaca
    35641 gaagaaggaa cagatcaaac aactagcacg acagaaaatc taaatggcat caaaaataat
    35701 gtgctctatg aagaagatca tttccatcca aataatttag gttatcaatt gatggcaaat
    35761 gcagtgagag atcagctgat cgagacacaa aaccaatggt tagagaagga ggatgatcaa
    35821 taaacatgaa aacaagatct gacgtatctt caaacaaaac aaagaaaaca aattactgga
    35881 aattcgcctt ccttatcctt cttggggtag tacttggttc gaccgtattt ttaggcagcc
    35941 gtatttttgc taatcgggaa ccagaactcc cagaaatacc agctcttacg gaaagacaag
    36001 gagatcctgt cttaacgatc aattcaaata aagaaaaagt caatcaaatc atcagctttt
    36061 tccttagtga gtatcaaaaa gatagtgata ttgaatataa attttatttg gaaaatgaag
    36121 cactactcaa tggtactttc gaagtactag gttttcctat cgatttctat ttatattttg
    36181 atccgtatgt gatggaaaac ggaaatgtcc aactaaaagc tagaagtctt tctatcggaa
    36241 cattgagttt gccaatcaaa gatgtgatga atatgatcaa gagaaactat aaattaccag
    36301 attggatcga agtcaataca gatgatctga ctatcatgct taggttggat caattccgaa
    36361 tgcaaaacgg gatgtatatt aaagcagata aaatcgactt agtaaatgat gacattcggt
    36421 ttagtctata tttgccaaaa gatacctctg atgcttcaaa caactcaaat accaacaaaa
    36481 ctagcaccag cagtactgaa agcaagacaa aagaaaataa aaaatcatcg gatgagtagt
    36541 attagagggg gaatcataat ggaacgagca atatttgcag gaggctgctt ctggtgtatg
    36601 atccagcctt tcgacacgct tcctggtatc catacagtga tgtcaggata tactggaggg
    36661 catgtaccag atccgactta tgaacaagta aaaagccaaa cgactggaca tacagaagca
    36721 gtggagatta tctatgatcc aacattgatt tcatatgaac aattagtaga actttactgg
    36781 cagcaaactg atccaactga cgctttcgga caattcgagg atcgcggtga caattatcgc
    36841 ccggtgatct tttatttgac agaagaacag cggatcattg ctgaaaaaag taagaaacag
    36901 ttagctgaaa gtggacgttt cgaacagcca atcgttacaa aaatcgaacc agcccaacca
    36961 ttttatctag cagaagaaga ccatcaagag tattataaaa agcatcctga aaattttaaa
    37021 agaaaccatg cacgccgggc tgcctttatc gaagaaaatt ggaggaacga agggtgaatc
    37081 gaagcttttt tcattattta atgacactgc gaggcggtgg cacacatgat gctttatctg
    37141 ttttcgctac agaagccggt aaagacatcc aatttcctaa gcacagctct agctacgaag
    37201 aaatttctaa ttatctggaa ctgaatgtcg actatttgcc gtccatggat atctttgacg
    37261 aagcatggga aaaatattta gaaaataatc atgacatata agagatagtt ttgtacttta
    37321 tgatcaaaaa agttttttgt ccaatagcct aattgaaaga attattttta tttcagctat
    37381 ctagtcgcat ttttttgata tttttcttat aataaagaaa gaatgaaaaa aagagggatg
    37441 gattgataga gattgacaaa aaaacaacgc tatattaatc gcttctggct tgtattcaaa
    37501 tacttacttg tttctgtatt ccttgcgttc atgttgcggg gatttttatt catcccggta
    37561 ccagtggaag gcaattcaat ggaaaacgtg ttgaagcaag gtgatatggt tgtgatggaa
    37621 aaattttcgg agatcagacg atttgatatt gttgtttttc aattagcaga tggcacgatt
    37681 tatatcaaac gagtaatcgg tcttccagga gaaaatgtca gctaccaaaa tgatcaattg
    37741 aagatcaatg ggaaagtagt taaggaacct tatctaacta aaaacctgaa atcagatcat
    37801 gcaaatgcat cctatacgac ggactttaca ctacaagagc taacgggaca atccaagctt
    37861 ccggaagata attattttgt acttggagat aatcgaagag tttcaaaaga tagtcgttcg
    37921 tttggcacga tcaataaaac tgatattcta ggtaaagcaa gatttgtcta ttatccactt
    37981 gatgaaataa aatggatcca gtgagaaaca ataaagcgtg cagtctgttg agactgcacg
    38041 ctttattgtt taatccaaaa tcagtttact accttagtac gtaaaatcaa acagctcgtt
    38101 taaacacttt tctagcctct aaagttttga taaatgaata aacaaccatt atttgaatag
    38161 ggatttggat catattcctg atgaatctac ctagaaaaat tactttgaaa tctgcaccaa
    38221 acaaaacaga catcagccaa gaattgataa aaaggctgac tgggatcata atcaataatt
    38281 gggcagcgat gacggaaggc aggtttatct ttttatgata taaaaataag ccattaataa
    38341 atccaccaag gaaagccgtg ataagaaaag cagcttgaaa cgttcctgaa ccaaatatcg
    38401 tgaaatttaa agtgttcgac aacatttcaa gcaaaccagc ccagatcggt ccatatagat
    38461 aacccataag cgccatactt aaaaatccga atgtgatttg aaaataagca ggaccaatcg
    38521 ctatcttgta taagatgaca tcaagggcta ataaaagagc agaggtcgac aacaatcttg
    38581 cattcatttc gggcaatcta aaaacgtctt ttgcaatcaa agtgttcaaa atattctctc
    38641 ctttgtcagt taataataaa aggataccat aaaatcacca atgtgtcatg acacattggt
    38701 gatttacata cactggcatc taacaattaa aaaaagggtg agaagactgc ttttataaac
    38761 tgtaaaaaag agattgtacg aataaaaaaa atagaggcgg agaatactta tcgtatcatc
    38821 cgcctttgtt tttttgttat aaaaaacgtc agattagtta tctgcttaca tcttcatcca
    38881 tacgggttct aatgtatttc cgtctagatc ttggacttct aatgaaaaca tttcttcttc
    38941 aggcattccc atatctactt cgtggaaagt accaccattt tcttttgcaa tttgagcaaa
    39001 tttttttact tcatccgcat tttcaacact aaacgaaatc aaagcaccac ttgttttttt
    39061 attatcagct atttctttat cttttataaa ttttttataa aaatcatgag agagaagcat
    39121 tatccaaaaa gtgtcatccc ataccattga accagcttct tcagtagaaa attcttcatt
    39181 ttttttaaaa cccagctttt cataaaaagc aacggaacga ttgacatcag caacaggaaa
    39241 attaacaaaa accatactat tcatttgttt cgtctccttt ctgttttgtt cgtctatcat
    39301 ctcttattta ggaaacgctg tcaaaaattt agattcatat atagaaacca aaataaaaat
    39361 ttgcatcatc aaaaaagtga agatgtgata gaatgaggac tggttcactt tcacttaact
    39421 aatagatgga atttctttat aataaaaaag tgaatttata ttgaaaaaga aaaaaacaag
    39481 taaagccggg gaatattccg gtatgaaagg aatggagaga acaatgacca tccaatggtt
    39541 tccgggacat atggcaaaag cccgacgaga agtttctgaa aaaatgaaat atgtggacat
    39601 cgtatttgaa ttggtagacg cacgattacc tttatcttct cgtaatccaa tgctagatca
    39661 gatcattcag caaaaacctc gccttgtttt attgaataaa gcggatctgg cagatccaca
    39721 acagacaaag ctgtggcaag aatattttcg taaacaaggc catcttgcat tagctatcac
    39781 ggcacaagaa agtaaaggaa ttaaaggtct agtacctgcg gctaaagaag cattgaaaga
    39841 aaaacgggca agagatgctg ctcgggggat caagcctcgc gctattcggg caatggtctt
    39901 aggtattcca aatgttggga aatctacgtt gatgaatcga ctagtaggca agaaaattgc
    39961 acagacagga aataagcctg gcgtaacaaa aggtcagcag tggcttcgtt taggtaatga
    40021 gttggaattg ttagacacac cagggatttt atggcccaaa tttgaagatg aagaaatcgg
    40081 caaaaaacta gcgctgacag gcgcgatcaa agaccagctt gtccatttag atgatttagc
    40141 gatttacgga ttagactttt ttgcccgata ttattcagga agaatcagcg atcgttatgg
    40201 tttatcaatc gagcaagaag aaaaattggc accggaatta ctgatggata ttacagcaaa
    40261 acgtgggtat aaagaagact atgatcgtgg cagcgaatta gtcgtgcatg atattcgtca
    40321 aggaaaactt ggacgataca cactggatcg ttgcgaagaa atggagcaaa aaagtgatga
    40381 ctgaatccat ccaaagtatc aaagaacgat tgaaaagcat acagagaata gatgatccta
    40441 cactagaatc attaagaaat gatccacgca aaggcgtgca gcaagcactg gcttcttttg
    40501 aacgacgatt gaaaaaggaa gcattaatta aggaaaaata tgaagaaatg ttttgctttg
    40561 aaaagcaagg gtacgcacaa ggtcaccaat ggattgccgg cattgatgaa gtaggaagag
    40621 gaccattagc tggacctgtc gtggcagctg cagttatctt gccgaaaaat gagatcatat
    40681 tagggctgaa tgactccaaa caattatcag agaaaaagcg agaacttctt tatcaacaag
    40741 ttcaagaaaa agccctggca atcgggatcg ggatcgttga tcagcagaca atcgatgatg
    40801 tgaatattta tgaagcaagt aaattagcga tgatccaagc agtagaaaaa ttgtccattg
    40861 taccaagcta tttgttgatc gatgcgatga ccttggattt gcctattcag caggaaaaaa
    40921 taatcaaagg ggatgtacga tctgtgtcga ttgctgctgc aagtatcatt gctaaagtat
    40981 atcgagacca attgatgaaa gaatatgacg tgctttatcc tggatatggt ttctcgcata
    41041 atgcaggtta tggaacaaag gaacacttag aaggacttga acgacaagga attacgccaa
    41101 tccatcgtaa aagttttgca cctgtaaaaa aatatttaca ataaaaaaca gccgctttta
    41161 cgtatcttat tagaaagaga gacgaaaggc ggttttatga tgtatcaaat agaagaaaat
    41221 ttattgaaac ttgcttatac aaaaggaatc agtagtcaag gaaaatgggc acttgctaac
    41281 tggatgatgc agtatcctta taaagaaatc ggatttgaag acatcattaa gataggtaaa
    41341 ataaccaaac accgggagct gtttcgcaaa agttggcagg aaattcacgc taactggggc
    41401 aaaatccaat cgaaacagtc gtttatcact tgctttgatc ccaaatatcc ccctcagctg
    41461 cttcacttga cctatccgcc aattgtactg ttttataatg gtgatctatc tttactttct
    41521 tgtaacatgt taagcgttgt tggtggaaga cacacttctg ctttagccaa aaaaacagtt
    41581 tattatttac taaaaccagt gatagaagct ggatatgtga tcgtcagtgg ctgcgcgaaa
    41641 gggatagata catacggtca ccaagcagca atctctcatg gtggacggac aatcgcagtc
    41701 attggaacag ggatagagca agtctatcct gctgaaaatc gtgacttgca agaggtgatt
    41761 gcaaatgatc atcttctttt gagtgaatat cctcctcaat ccggcccgaa aaagcattgt
    41821 tttccaatga gaaatcggat tatcgcagct ttgtctaaag gaacatgtgt ctttgaagcc
    41881 aagaaaaaaa gcggctctct gataacagca cagcaagcat tggatcttgg aagaacagtt
    41941 ttttctgttc caggaaatat tttaacagaa cattctaccg gatgtcatca tttgatccaa
    42001 gacggtgcag tttgcacggt ttcgggtgaa gatatcttgg cagaatttaa agaataacac
    42061 catacttttc atttgctttt cttgacaaac gttttctgaa tggatatgat tagctacgat
    42121 ttgtatgaat cctcttttaa tagtaggaac acgacaatgg aaaggagtcc attcagtaat
    42181 ggcgtataaa tatttagtga ttgtagaatc acctgcaaaa gccaagacaa ttgagaaata
    42241 tcttggacga aactataaag taatggccag tgttggccat ataagagatt taccgaaaag
    42301 taaaatgggt atcgattttg aaaacaatta tgaaccccat tatatttcta tacgcggaaa
    42361 aggcgatgtc atcaaaagcc tgaaagccgc agcaaaaaaa gctcaaaaag tttacttggc
    42421 aagtgacccg gatagagaag gagaagcgat tgcttggcat ttagcgtacc tacttgggtt
    42481 ggatctgaaa gaaaaaaatc gggtggtctt caatgaaatc acaaaagacg cagtcaaagc
    42541 agcttttaag gaaccaagaa cgatcgatgt agatttagta gatgcacagc aagctcgtcg
    42601 taccttagac agaatcgttg gttattcgat cagtcctatt ctctggcgta aggtcaagaa
    42661 agggttaagt gcaggacgtg tccaatctgt cgctttaaaa attattattg accgtgaaaa
    42721 agagatccga gaatttgttc cagaagaata ttggagcatc gacggtaatt ttaaaaaagc
    42781 tcgcaagaaa ttcaaagcaa atttctgggg aatcgacggt aagaaaaaga aattaccaga
    42841 tgcacaaagt gtaaaagaag tcactgctag aattgatgga acagacttcg aagttaaaaa
    42901 agtagaaaag aaagagcgca aaagaaaccc tgcgaatcct ttcactacaa gtagcctgca
    42961 acaagaagct gcccgtaagt taaactttcg aacaagaaaa accatgatgg tagcacagca
    43021 attatatgaa ggaatcactt tgggtaaaca aggaacagtc ggcttgatta catacatgcg
    43081 tactgattct acccggattg ccgatacagc aaaagcagag gccgcagcat ttattgaaga
    43141 tacgtatgga aaagaatttt ctagacatga tcaccgaaag atcaaaaatg ctcaaggcgc
    43201 acaagatgcc catgaagctg tgcgtccaac gagtgtgctt cgtacaccag atgaactcaa
    43261 acaatattta gataaagatc aattgaaact ttatacattg atctggtcac gttttgtggc
    43321 tagtcagatg acaccagcta ttttagatac aatgaaagtg acattagaac aaaatggtgt
    43381 catcttcatt gcgaacggtt caaaaatcaa attcaaagga ttcatgcaag tgtatgtgga
    43441 aggtagagat gacggcaaag aagagaaaga aaatattctt ccagaacttg aagaaggcga
    43501 tgtagtccaa tctgttgata ttgaaccaaa acaacatttt actcaaccac cagcacgttt
    43561 tagtgaggct acgttgattc gtgcactaga agaaaacggg gtagggcgac cttccactta
    43621 tgcaccaaca cttgatacga tccaaagacg ctactatgta aaattgacac aaaaaagatt
    43681 tgagccgact gaactaggag aaattgtcaa ttcattaatc tgtgaattct tccctcaaat
    43741 cgtcgatatc catttcacag cagaaatgga aggagatttg gataaaattg aagaaggcac
    43801 ggaagcgtgg gtcaaagtgg ttgatcgttt ctataaaccg tttgaaaaag aactgacgaa
    43861 tgcggaagaa aaaatcgaaa aaattcaaat caaagatgaa ccagcaggat tcgattgtga
    43921 tgtctgtgga catccgatgg tgataaaatt agggaaatat gggaagtttt atgcttgcag
    43981 taattttcct gattgtcgga atacgaaacc aatcgtaaaa gaaatcggtg tgacttgccc
    44041 agtatgtcat gaaggacaag tcattgaacg aaaatctaag aaaaacagac tattctatgg
    44101 ttgttcccgt ttcccagaat gtgaattcac ttcttgggat aaaccagtgg gcagaaattg
    44161 tccaaaatgt gacggatatc tggtcgagaa gaaagtcaaa ggcggtaaac aagtagtctg
    44221 tgtaaatgga gattacgaag aagacatcca aaaataatag aaaagaggtt ctttcattga
    44281 aaatggtaaa tgttgttgga gcagggcttg ccggaagtga agctgcttgg cagatcgcac
    44341 aagcaggagt ccctgtccgt ttatatgaaa tgcgtccagt caaatcgact gaggcgcatc
    44401 acacaagtaa ttttgctgaa ctagtatgtt ccaattcatt aagaggaaac agtttggcta
    44461 atgcagtagg gttattgaaa gaagaaatgc gccgattgaa ttcggtagta atcacttcgg
    44521 cagatgaaac agcagtgcca gctggtggtg ccttagctgt tgaccgcgat tctttttctg
    44581 aaacaattac ccgaaaagtc aaagagcatc cattagtaac agtgataaac gaagaaatta
    44641 ctgaaatacc ggaaggaatc accgtagtag caacaggacc tttgacttct catccattag
    44701 cagaaagcat caaagcattc aatggttcag atggttttta tttctatgat gcagctgcac
    44761 caatcgtaga caaagctacg atcgatatgg ataaagtata tttgaagtcc cgctatgaca
    44821 aaggagaagc agcttacttg aactgtccga tgacagaaga ggaattcaaa gctttccatg
    44881 aggcactaat caatgccgaa gtggcagaac ttaaatcttt tgagaaagaa aaatattttg
    44941 aaggatgtat gccaattgaa gtaatggcac agcgaggatt caaaacgatg cttttcggac
    45001 ctatgaaacc agttggattg gaagatccta aaactggcaa acgtccttat gctgttatcc
    45061 agctgcgtca agacaatgct gcagcttctt tatacaacat cgtgggcttt cagactcact
    45121 tgaaatgggg cgagcaaaaa cgtgttttcc ggatgattcc tgggttagaa aatgctgaat
    45181 tcgttcgcta tggtgtgatg caccgaaaca gctttatgaa ttcgccagaa ttgctgaaac
    45241 cgacttacca atcaacgaaa cgcgaagatc tgttctttgc aggtcagatg actggtgtag
    45301 aaggctatgt tgaaagtgca gcgagcggac tacttgctgg aatcaacgcc gcacgcttag
    45361 caaaagaaat ggaaccagtc gagtttccac aagaaacagc tattggaagt atggcttact
    45421 acattactca tgcggaagga aaacatttcc aaccgatgaa tgccaactat ggtctgtttc
    45481 ctgaactgcc agagcgcatt cgagacaaaa aagcaagata tgaagcaatt gcacaacgag
    45541 ctttaaaagc taatgaggca ataaaaacag aattagaaaa aactgcaatc ccaaatgagt
    45601 aaggaaactc catgaagagg gtgagacgga tagtctcgct ctttttcttg cgtttttctt
    45661 aagaatttct caaacaaaat gtgaggaatt gcgccaattg tgaacaaact tagaaatatt
    45721 ggttaaattc tgacaattta tttgtctttt tataaacgct gtgctaaatt attctctggg
    45781 acaaaaggaa ggtgagaaaa tgacagaagc cacgtgggaa caaaaatttt tgcgttattt
    45841 gattgtcgaa agaggatatt cagaaaaaac gaaagaagca tatgaagaag acattctcca
    45901 tttcaaacat tttttggagg aatctggaga cgctgatctg ctgaaggcgg aatattttac
    45961 ggttcgtgtc tatttgagtg cattagctga tcatcgtcct agctatagca gaaattctat
    46021 cagtcgcaag atagccagcc tacgttcgtt ttatcagtat cttctcaaag aagaagtgat
    46081 aaaagaaaat ccattttctt acgttcatct caaaaagaaa aatttgagac tgccacgttt
    46141 tttttatgaa aatgaaatgc aagcactttt tgacagcgta gcaggagata gtcctttgga
    46201 tttgaggaac cgcgctttac tggaagtcct ttacgggtca ggcatccgtt taagtgagtg
    46261 tagcagtttg tcggtatcag acattgattt tgattcagag gtcatgttga tccatggtaa
    46321 agggaacaaa gagagatatg ctcctctagg ttcttttgct caagatgctc tgcaagaata
    46381 tttcagggaa ggccgccagg tattgatgac aaaatatcac gaagagcatg atatcgtttt
    46441 tgtgaatcat catggaaaac caatcacgcc tactggaatt gaatatgtct tgaatcaaat
    46501 gatcaaaaaa agcagtttgg atagtgatat ccatcctcac atgctgcgcc atacatttgc
    46561 tactcattta ttaaataatg gggcagattt gcggacagtc caagaattgc taggacatgc
    46621 caatttatcg actacccaga tctatgccca tgtaacaaaa gaaagtttac aaaaaaacta
    46681 tcgttctttc catccaagag cgtaaaaata aggaaaagaa caaatttagg aggaaacaaa
    46741 catggtcgaa tcaccatttc attcaaccac tatctgtgcc gtcgaaaaag acgggaaatt
    46801 tgctatggct ggagatggcc aagtaacaat gggtgaatct gttgtcatga aaggcactgc
    46861 aaagaaagta cgacgtatct acaatggaga agttgttgta ggtttcgccg gaagtgttgc
    46921 agatgcgttt actttagaag aaaaatttga aggcaaacta aacgaatata acgggaatct
    46981 acaacgcgca gctgtcgaat tagctcaaga atggcggaca cagcaatcta tgcaaaaact
    47041 tgaagcgatg ctgatcgtaa tgaatgataa agaaatgctt cttgtttcag gtacaggaga
    47101 agttatcaca ccagatgatg gtatcttagc tatcggatca ggagggaatt ttgcgttggc
    47161 tgcagcccga gcaatgaaaa actatgctca aaacgacatg agtgcgaaag aaattgcaga
    47221 aaatgcgtta aatattgccg cagatatctg tatctttact aatcataata ttatcgtaga
    47281 agaactgtaa gaggtgagta gatatgtatg aattaaaaca aacaccaaga caaatcgtaa
    47341 gtgaattaga tgaatatatc gtaggacagc acgcagcaaa aaaatctgtt gccgttgctt
    47401 tgcgtaaccg ctatcgccgt ttgcagttag atgaaaaaat gcaacaagat attacaccaa
    47461 aaaatatgct gatgatcgga cctacagggg tcggtaaaac agaaatcgca cgacgtttgg
    47521 caaaaatcgt caatgcacca tttgtcaaag tcgaagcaac aaaatttact gaagtcggtt
    47581 atgtcggaag agatgtagaa tcaatggttc gggatttagt agaaaatgcg atccaaatcg
    47641 tagaaaaaga gcagtacagc cgtgtataca caagtgctaa aaaaaatgca gaaaaacgtt
    47701 tggtaaaaat cttggtacct ggtatcaaaa aagaacagaa acaatccact aatcaatttg
    47761 aacaaatgat gaatcttttt aatgctagtc agcaaaatac cgctgaaccg caagaagaag
    47821 tgacagaaga tattcgaatc aatcgccgta cagtcttgga acaactacaa aagggtttac
    47881 tggatagtcg tgaagtaacc attgaagttg aagaccaaaa gaaacctgca ccaatgatga
    47941 acaatggatt ggagcaaatg gggatcgacc taaatgaaac tctaggtgct ttgacaccga
    48001 agaaaaaagt ggaacggacg gtaacagtca aagaagcttt agagttattg atcaaggaag
    48061 aatcagcaaa attagtcaag gatgctgata tccatagtga ggcaatcaaa ttagcggaag
    48121 aaagtggaat tatttttatc gatgaaatcg ataagatcac ttctaaatca cagcaatctg
    48181 gagaagtatc cagagaaggc gtccaaagag acatattgcc aattgtcgaa ggttcacaag
    48241 taaacacaaa atacgggatc atccaaacag atcacgtcct attcattgct tcaggagctt
    48301 tccatttgtc taaaccaagt gatctaattc cagaacttca aggacgcttc ccgatacggg
    48361 tagaattaga tgatttgaca gctgaagatt ttgtgaagat tctgaccgaa ccaaataatg
    48421 ctttagtaaa acaatacgtc gcgttgatcg gtacagaaaa tgtgtcagtt acgtttacaa
    48481 aagaagcaat tgaacggatc gctcaaatcg ctttcgatgt caaccgtgac acagataata
    48541 tcggcgcacg cagactgcat accattttgg aaaaactact agaagatcta ttatttgaag
    48601 caccagatat gcaaatggga gaaataacga tcacagaagc atatgtggat gacaaacttg
    48661 gctcaattgc ggcaaatgaa gatttaagtc gctatatttt ataaaaaatc ggaggacgac
    48721 aatgacagac ttgctaacga aaacccgcaa gataaacaca cttttgcagc aaaagaatac
    48781 ttttgacatg caagcagatt tgccttacga taaaatggct gtcacactag gtggtattct
    48841 tgacagcaac acctatatca taggaagtga cggagtatta ctaggttata atgaacgtca
    48901 cgatgtgaac aatgaacgaa tcaaaacaat gtttgttgag aaacaatttc ctgaatctta
    48961 tactgataca gtggcacagt tgatgaaaac tgaagctaat atcccaatta ctagtgatat
    49021 tactgcattt ccggtagagt caagagagaa atatccattt ggtctgacga ctgtcgttcc
    49081 gatctttgga gctggcgaac gtttgggtac gattatctta tctcgtatgg aacaatcgtt
    49141 tgcagatgac gatctagtct tagcagaata tggagctacg gttgtcggta tgcagatcct
    49201 ttatcagaag tctcgaagca tcgaagcaga tgtacggagt gcaacggctg tccaaatggc
    49261 aatcaacaca ttatcttata gcgaattgaa ggctgtacaa gctatctttg aagcattgga
    49321 tggagatgaa ggtcgtctga ctgcttctaa tattgccgat agtatcggca tcactcgttc
    49381 tgtgatcgtc aatgctttac gaaaattgga atcagctgga atcattgaat ctcgttcgtt
    49441 aggcatgaag ggaacttatt taaaagtatt gaattcccgt tttaaagacg agttagcaaa
    49501 acacagttat tagaagtaag gggactgggg cagatagaaa tgtttgttcc agccttccca
    49561 ttttaaaaag taagtcgaag ttggaggaat ggcaatgact gttattattc aaaatgacca
    49621 gctgatcgcc gaaatcgctg aacacggtgc ggaattgatc agtctgaaat caaaagaaca
    49681 tggtttagag tatatctggc aaggtgatcc agcgtattgg ggcagacatg caccggtttt
    49741 attccctttt gttggacgtt taaaagatga tcagtatgtt tatcaaggga aaacatatca
    49801 aatggggcaa cacggatttg ctcgggatat ggattttgaa gtcattgaac atggacaaga
    49861 aatggctagt ttcatcttaa ggagtacgcc ggagacatta gaaaagtatc catttgattt
    49921 tgaattagtg atcagctatg aattaggagg agacggcatc acggttcatt atcaagtggc
    49981 aaataccggt gaaaaagaaa tgttcttttc tatcggtgga catcctgctt tcaatgtacc
    50041 tcttgaagaa ggattgtcat ttgaagattt ctatctggca ttttctccat tgaaatcaag
    50101 attacgccta ccattgaaag gcccattcat cgatatggat caaaagacgt taggtcagac
    50161 aaatacgaat ctggctttga atcgtgaact ttttgagcaa gatgccttgg tttttgaaac
    50221 aaggggtcta aatgcgtacg ccattcgaag tgaaaaatct tcccatagcg taactttaag
    50281 ctataaagat atgccttatg tagggatctg gtctccttat ccaaaagaag cgcctttcgt
    50341 ttgtatcgaa ccgtggtgcg gaatcgctga cacggtgaac agtagtggaa acttgatgga
    50401 aaaagtaggg atcaatcaac taggtgccca tgaaatcttc aagacaaaat attccatcac
    50461 agtgaagtaa gaggttgtga ccgagaagtt agcagggaac accgtttacc aaggtgtgta
    50521 aaaaagctat cctgtaagta ataagggagt gtgacatcga tttgtcacac tcccgtttta
    50581 tctctttgga atgaaaaagt atcaggattt tttcttgctg ctattcaaac caaacgggat
    50641 tcgactttca gtatggtttc tgatacgctt gatattgtct ttatgccgat aaaagataaa
    50701 ggaagaaact aaaaaggcaa tgatcgtcag taaccaattg ggcttagcca aaatcacagg
    50761 agctacataa ggaaggacga tcgtagataa agtgatcaat actgcactga tcatactgct
    50821 caaactcacc atacttgtac aaaataaact aacgataaag atgatacaag aataaacaaa
    50881 aaatacagga ttaaatccta aaagcattcc tgcacttgtc gcaacagctt ttcctccttt
    50941 gaacccagca aaaatcggaa atgtatggcc aagaatggcg cataccccaa accaaagagg
    51001 gttaatccca gaaaggtgga agatcatcgg caaacaagta gccaatgtac cttttaaaat
    51061 atccataagc aggacaacaa tcccggctgt tttgcctaat acacgaaatg tattggtcgt
    51121 tccagtatta ccgctcccgt gttgtcggat atcttttttg aaaaacaatt tgccaatcca
    51181 gacaccggaa ggaatagaac ctaaaagata tgctaaaata agtaataaga tcaatttcat
    51241 tttttaccct ctttcaagtt gaaaactatc ctttatttta gcatgaatag gtaacaggaa
    51301 caattgaaaa aatgaaagat acaagtataa tagatggaat aaaaagaaaa gcaaggggtg
    51361 gcagaaatgt ctgtaaaaaa tccaacacaa gaaacgattt tcaactattt ggaagaagca
    51421 aaaaatattg ccgtcgtagg cttgagcaat aaaccagaac gaacaagtta catggttgca
    51481 caggtattgc aagacaatgg atataaaatc ataccagtaa atccattatt ggctggtgaa
    51541 gaaattctag gcgagaaagt ctatgcgaat ttgacagaaa tcgatgatcc aatcgatatc
    51601 gtagatgtat ttagacggag tgaattttta cctgaaatag caggtgattt tttgaaaact
    51661 gatgctaaag tgttctgggc acaattaggg attgaaaaca aagaagcagc tgagatgcta
    51721 agaaaagcag gacgtacaga tatcgtaatg gatcgttgta ttaagattga acttggtaag
    51781 ttgaaagaaa accaaaaata aaaatgacca caaagaagag atgatcgata gaggggaatg
    51841 tcgaaaaagc ggttaggaga taattaaaat tgatttctcg tctaccctct tttttttcac
    51901 gaccttttct agtatgataa tcgtggtgcg gttttgccgc aaagtattat tgaaggagcg
    51961 tttgccttgg caaaaaaagt aaacaacgaa tacaatgact cgtccatcca agtattggaa
    52021 ggattagagg cagttagaaa aagaccaggg atgtacattg gatccactga cagccgaggc
    52081 ttgcatcatt tagtctatga aatcgtcgat aatgcagttg acgaagcatt atcaggttat
    52141 ggcagtgaga ttgatgtgac catccatgaa gacaatagta taactgttgc agatagcgga
    52201 cgtgggatgc ctgtaggaat gcatgcttcc ggaataccaa cagttgaagt gatttttact
    52261 gtgctgcatg ctggcggaaa gtttggtcaa ggagggtaca aaacttctgg tggactgcac
    52321 ggtgtaggag ccagtgtggt aaatgcctta tcgaaatggc taattgtaac gatcgttaga
    52381 gatggcgtag agtatcagca gaaatttaaa aacggcggta aacctgacgg tactttgaaa
    52441 aagataggaa aaacaaaaaa agcaaacggg acgactgtcc attttttacc agatgataca
    52501 atattcagta caacgaaatt ttcatatgaa attttagccg aacggttaag agaatctgcc
    52561 tttcttctaa aaggcgttaa aatctctctt tctgatcttc gtggagaaga accagtcaag
    52621 gaaatttttc attacgaaga aggaatcaaa gaatttgttg attatctgaa tgaagaaaaa
    52681 gatacattga caccagttgt ttatttttca ggagaaaaag aaggtatcga agtagaggtc
    52741 gcttatcaat acaatgacgg ttattcagaa aatgttttat cttttgtcaa taacgttcgg
    52801 acaaaagatg ggggaaccca tgaagctggt atgaaagcgg cgatgacgaa atcttataat
    52861 gaatatgcga gaaaagttgg tttgctgaaa gaacgggaca agaatctgga aggtagtgat
    52921 ttcagagaag ggttagctgc tgtactttct atccgtgtac ctgaaaatct tctgcaattt
    52981 gaagggcaaa caaaagaaaa acttggtacg ccagttgctc gtaccgtagt agataacgtc
    53041 atcagtgaac aaatgggctt ttatttgcag gaaaatagcg aaatgagcca gatgttggtc
    53101 cgtaaagcaa tcaaagccag agaagcgaga gaagcagcac gtaaagccag agaagaaagc
    53161 cgaaatggga agaagcgtaa aaaaggcgaa tctcttcttt caggaaaatt gacacccgca
    53221 caatcccgaa accctaagaa aaatgaattg tatttagtcg aaggggattc tgctggcgga
    53281 tctgctaaac aaggaagaga cagaaagttc caagcaattc tacctttacg aggaaaagtc
    53341 atcaataccg aaaaagctaa aatgcaagat atcttgaaaa atgaagaaat caatacgatg
    53401 atctatacga ttggtgcagg agtcggtcct gagttttcta tcgaagactg taattacgac
    53461 aaagtaatca tcatgaccga tgcggataca gacggcgccc atattcaagt attactgctt
    53521 actttctttt atcgttatat gaaaccgctg attgaagctg ggaaagtata tatcgcgtta
    53581 ccgcctttat ataaagtatc caaaggacaa ggaaagaagc aagtcattga atatgcgtgg
    53641 acagatgacg aattggcagc aatgattaaa aaagtcggca aaggatatat gctgcagcga
    53701 tataaaggac ttggagagat gaatgcggaa caattgtggg aaacaacgat ggatccgact
    53761 tcccgtacgt tgatccgcgt ccgtatcgat gatgctgcgc aagctgaacg tcgagtaacc
    53821 acactgatgg gtgacaaagt agaacctcga agaaaatgga tcgaaaatca cgtgcaattt
    53881 acgctcgaag aagatggcag tatcttagat aaaaaagagg atactgaaat ctctccttca
    53941 gtttctaatg atttattaga tgaagaacga gcagataaaa atgaaaacaa tcagttattt
    54001 gaagtagaat aggaggtcac ctgatggaaa atcgacaaga agtacaagaa ttaactttag
    54061 aagaagtgat gggtgaccgc ttcggacgtt attccaaata tattatccaa gaacgtgcac
    54121 tgcctgatat ccgtgatgga ttgaagccag tgcaacgccg gatattattt gccatgaaca
    54181 aagatggcaa tacgtatgac aaaggattcc gtaaatcagc aaaatctgtc ggaaatatca
    54241 tggggaatta tcatcctcat ggtgacatca gtatttatga agcgatggtc cgcatgagcc
    54301 aagactggaa gttgcgggaa gtactgatcg aaatgcacgg gaataacggg agtatggacg
    54361 gtgatccacc tgctgcgatg cgttatactg aagccagatt atccaagtta agtggagaga
    54421 tgctagcaga tatcgagaaa gaaacagtcg atctcgtgtg gaattttgat gatacagaaa
    54481 aagaaccaac agtccttcca gctcgatacc caaaccttct cgtcaatgga tcgacaggta
    54541 tatctgctgg atatgcaaca gaaatcccga ctcataactt agctgaagtg atcgatggca
    54601 caatctatat gatcgatcat ccacaagcga gccttgaaaa attgatggaa tatattcctg
    54661 gacctgactt tccaacagga gggatcttgc aaggaaaaga tgaaatcaaa aaagcttatg
    54721 aaacaggacg aggaaaagtt attcttcgtt cgaaaacaaa gatagaggca atgaagggta
    54781 ataaacagca aatcgtgatc acagaaatcc catatgaagt aaataaagcg accttggtga
    54841 aaaaaatgga tgagatccgt ttgaataaga aaatcgatgg aatagctgaa gtacgagatg
    54901 aaagtgatag aacaggtctg caaattgtcg tcgaattgaa aaaagacgcc aatgctcaag
    54961 gaattttgaa ttatttgttc aaaaacactg agctacagat caattacaat ttcaatatgg
    55021 tcgctatcga ccatatgact ccgcatcaag ttggactgaa agacatttta agaagttata
    55081 tcgagcatcg aaagcaagtc ataacaaaac gtagtcaatt cgatttagcc aaagctcaaa
    55141 aaagacagca tatcgtagaa ggattgatga aagctttatc gattctggat gaagtaatcg
    55201 caacgattcg tgaaagtaaa gacaaaaaag acgccaaaaa gaatttagtc gacgtctttc
    55261 aatttacaga agaacaagca gaagcaattg tcacattgca attataccgt ttgacgaaca
    55321 cggatatcac agagcttcaa aaggaatccg aaagcttgat tgcgcaaatc acagagttga
    55381 ataaaatcct ttcaaatgac aaagagcttt tctctgttat gaaaaaagaa ttgcgagaag
    55441 tgaaaaaaaa ttattcttcc gctcgtctaa cgacaatcga agacgaaatc gaagaaatca
    55501 aaattgatac gcaagtctta gtggcacaag aagacgtaat tgtcagtgtg acgcgagaag
    55561 gctatgtgaa gcgaacaagc cttcgttctt atagtgcttc caaaccagaa gaaatcggga
    55621 tgcgagaagg cgactacttg ctatactcag gtgaattgag tacattggac catgttcttc
    55681 tgatcacaaa taaagcaaat gtgatctacc gccctgtcca tgaactaccc gatttgaaat
    55741 ggaaagatgc tggtgagcac atttctcaaa caatctccaa tctgtctgta gacgaatcga
    55801 ttttagctgt tttcccatat caaaaaattc aagcagagaa aacatttgta ttcatcagca
    55861 agaatggatt gatcaagcaa acacgaatga cagagttcga accatggcgc acctataaga
    55921 gccgtccgct cagctgtatg aagctaaagg cggaagaaga tgaactgatt gctgtgtatc
    55981 tgaaagaaga tcagccaggc ttagatgttt tcttagtaac gcatcaagga atgggtttgc
    56041 gctatccttt aacagatgtt cccgttgttg gagcaaaggc agctggagtg aagtctatga
    56101 atttgaaaga tggagatagg attatcaacg ggctgcttgt gttagcagaa ggtgatacgc
    56161 cgatcgtaat cgttactcag cgaggagctg ttaaacgcat gcttgctcaa gaaatcagcc
    56221 aaacttcacg tgcgaagcgg ggagtgacgg tcatgcgtga gctgaaaaaa aatccgcacc
    56281 gtattatcta tatgtcggaa ggaagatcaa aagaaataac cttgatgaat caaaaagggc
    56341 agcagttaac gattgaccca actgatttcc ctataggtga tcgaacatcg aatggatcat
    56401 ttgcgatgga tgagaaaaaa ggtggagaag tcatcgaagt tatcgatgct cctgagattt
    56461 tcatcgagtc gtaactgttg tagtatttta atgaagagac gccatctgta ttaataggct
    56521 ctttgtcaat aaggactgat gagttgtgca aa
//
LOCUS       DACGLI010000201        20943 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.052, whole genome shotgun sequence.
ACCESSION   DACGLI010000201 DACGLI010000000
VERSION     DACGLI010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.052"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(101..544)
                     /locus_tag="IXT22_003072"
     CDS             complement(101..544)
                     /locus_tag="IXT22_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4864349.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINAMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(739..2079)
                     /locus_tag="IXT22_003073"
     CDS             complement(739..2079)
                     /locus_tag="IXT22_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4864350.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGIILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHAADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFAAYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLIIFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLTLRKGTLW
                     DKGISFFALAVLWLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2361..3257
                     /locus_tag="IXT22_003074"
     CDS             2361..3257
                     /locus_tag="IXT22_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4864351.1"
                     /translation="MNKNDVLLIAKNKSLYFFPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMDFSSSEPKTDLFFGATNNGRKERAEKYKQEFTKR
                     GVTTNYFILPLRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYQFYHSENIFLLQERDLDELPEFLHTPFQPIPSELLEFFDAENWAKR
                     FFTTDSAIYEQYEYDLSSVKNK"
     gene            complement(3400..4341)
                     /locus_tag="IXT22_003075"
     CDS             complement(3400..4341)
                     /locus_tag="IXT22_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4864352.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVVLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNKHVDLIVALTKANQLDDMFRSIQSIITENTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEAKLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAEGM
                     VRTIVSEFASIAAKEGITLDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAVWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4467..5588
                     /locus_tag="IXT22_003076"
     CDS             4467..5588
                     /locus_tag="IXT22_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4864353.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALGGTWRTIDGMDLLFRQRKISYLLTNWQGKNTAVIESAQVLGLDLLDKP
                     TDQTIRLASSYALGELIKDTLLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTRKLHLDRRNVLVSKVKVIIAADVTNPYTGQQGAAWQFGRQKGGTDTTLAFLD
                     KQAEKIAQQIKDVWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFELVSQITGLEKQI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDRELEGLFDFLPIV
                     LSIQLGPIDLEEAMEHRQTLEKTEILGQTLSRFFNILPK"
     gene            5846..7348
                     /gene="lsa"
                     /locus_tag="IXT22_003077"
     CDS             5846..7348
                     /gene="lsa"
                     /locus_tag="IXT22_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lsa family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4864354.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQAFVYFPQQTKDKERLTYYVLNEIMDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEIAKNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKKVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDALTMNSQVSHHKRLLSVENLQLGYENLLFEPVHF
                     TIEPHQRMAISGPNGAGKSSIIHYLLGTFNGKVVGEKSQPKHLTISYVRQNYEDNRGT
                     LAEFAKKNRVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYI
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLEKI"
     gene            7415..7942
                     /locus_tag="IXT22_003078"
     CDS             7415..7942
                     /locus_tag="IXT22_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4864355.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQALAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVVDRLNLPMTADERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECMEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELISYE"
     gene            8154..9215
                     /locus_tag="IXT22_003079"
     CDS             8154..9215
                     /locus_tag="IXT22_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4864356.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQNRLIELGSEAKKNKLELMVDISGEALKRAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPNDIDELKEAAADFSQIEAWHNYYPRLETGLDKEWYQEK
                     NQWLKTQGFLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSEHVQEQFASFQKEQTVLLHTEPVDEVFYEYILGKHTNRQDDARDVIRSADARF
                     REIPPIPVRNTAKRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9218..10114
                     /gene="murQ"
                     /locus_tag="IXT22_003080"
     CDS             9218..10114
                     /gene="murQ"
                     /locus_tag="IXT22_003080"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4864357.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELPSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISEHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEAAQAKLAEANGFVKGTL"
     gene            10128..12110
                     /locus_tag="IXT22_003081"
     CDS             10128..12110
                     /locus_tag="IXT22_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4864358.1"
                     /translation="MAKNELTLEELAKQIYQGAGGMGNVESIVHCMTRVRMKVINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQEMVDLAGVKLGEKLPSASATTAS
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAGTWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALATGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKAVPQASA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVISSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAADK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="IXT22_003082"
     CDS             complement(12180..12626)
                     /gene="nrdI"
                     /locus_tag="IXT22_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4864359.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEYEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQRFGFPFLADYELRGTPSDVTRVYQILAEKNK"
     gene            12837..14261
                     /locus_tag="IXT22_003083"
     CDS             12837..14261
                     /locus_tag="IXT22_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4864360.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNVASIVMSTIFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFINNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGFLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14438..15211)
                     /locus_tag="IXT22_003084"
     CDS             complement(14438..15211)
                     /locus_tag="IXT22_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4864361.1"
                     /translation="MTLLIKQELFKLIKKKSTAVLSVLLVALLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMESQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSIYLYLLAIIVTVLMKLILFPSISFTEKISTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIALFLALGYLVFKRKNV"
     gene            complement(15208..16113)
                     /locus_tag="IXT22_003085"
     CDS             complement(15208..16113)
                     /locus_tag="IXT22_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4864362.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSEGTIRIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVKQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDQAARTILTDAGYPLEDPDKIKLLKKNEELLGTVIQLLSAENVHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16274..16594)
                     /locus_tag="IXT22_003086"
     CDS             complement(16274..16594)
                     /locus_tag="IXT22_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4864363.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGLLLISIIGIKI
                     TSGH"
     gene            17067..17753
                     /locus_tag="IXT22_003087"
     CDS             17067..17753
                     /locus_tag="IXT22_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4864364.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17755..18699
                     /locus_tag="IXT22_003088"
     CDS             17755..18699
                     /locus_tag="IXT22_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4864365.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18898..19542
                     /gene="pcp"
                     /locus_tag="IXT22_003089"
     CDS             18898..19542
                     /gene="pcp"
                     /locus_tag="IXT22_003089"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4864366.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19621..20898
                     /locus_tag="IXT22_003090"
     CDS             19621..20898
                     /locus_tag="IXT22_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864367.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6757 a         3774 c         4370 g         6042 t
ORIGIN      
        1 cacaacctct gattcacggt gttccagaag tagcttcttc ttatttcttg aagttgatca
       61 cttctggaac atcctctttt tttatttgga tggataatgg tcattccatt tctttgatca
      121 tttttttcat tttgtcgatt tcttcttctt gtgcctgaat gatttcttcc gctaattttt
      181 ttacttcagg atcttttaaa tcagctcgtt tacttgtcaa gatagcaata gagtgatgag
      241 ggatcatcgc cttcatccac gccgtatcgt tgacagttgt ttggcttcgt accataaata
      301 aggaaccggc aaaaacaaga agactagcgg ctaaaatcat agcatttatc tttttgtttt
      361 catacatttt ccacatgaac aacaacatga tgactgccat gactgcaccc atcatcaacg
      421 ccatgaatac acgtgtgcga ctgaagaaga tatgatcaag cgcataaaca ttcaaataca
      481 tcataccaaa catgactacc gtcgaaacac caatcatcaa caaaaacttc caatactttt
      541 tcatttaaaa caaactcctt tttcttcatt cctttcttct atcatgtcat gagcgtggag
      601 aacaatcaat taatctgcac agatggtttt tgaacaccgt ttattcggaa aaaagaactg
      661 caacaatttt tgtcgcagct cctttttttc aatagctcca gatattcaat ataaatagaa
      721 taaaattctc tattggtttc attcattcgt caagacgaaa gcatcattct ttttttgata
      781 actgaaataa atgaacaggt aaagcaaacc ggtcaataca gttaccccaa tggagttcgt
      841 gaataggata ccaaggaaaa tcaaccataa gactgctaat gcaaaaaagc tgattccttt
      901 gtcccataac gttcctttcc ttagtgtcag tacaaaggac gcagcactga taatgatcca
      961 gatcaataat actgtatagg aaagagaacc tgccagatag ccaaataatt tgtcaccgac
     1021 aaaataagaa agagccacac ctagataaag aacactggta caaaacagca cagcacgttg
     1081 cggtacttga tgcttgttta aaacagctag ttttctagag gaacctttcc gatctttcaa
     1141 gcggaagaac aaaattctcg aagaagcata tacacctgaa ttgatagacg agaacagagc
     1201 aagaacaatc acgaaattga cgatatctgc cgcaaatgga atattcattt tttcaaatac
     1261 catcacaaaa ggactaacgt tcgtgcctgc taaagtattc caaggaaaaa taatcaaaag
     1321 caaaaataaa ggaataatgt aaaaggaaat gattcttccc atgacgcctt tgattgcttt
     1381 aggaatcgca cgtttaggat catctgcttc gcttactgtg atagcaatca actcagaacc
     1441 gccgtaagaa tagataacta caagcaaaga actgatgatt cccttcatac cgtggggagt
     1501 aaaaccacca tgatcagtta attgttgaag ggtagggaaa acaccagtac ccaacatttg
     1561 ctgaccgaca agataagcag caaaaatgat caataggata atgacactga ttttagcaaa
     1621 ggccagccaa tattctgtct ctgcgaataa tcgtaccgaa taaagattga tgatagtagt
     1681 taaaacagcc aacataaaaa caaataccca agctgggatg tgggggaacc acaactgtaa
     1741 aaaggaagca gctgcaacag cttcagcaat gatattgata atccacatgg accagtagac
     1801 ccaatcggta aaatcggcag catgagcacc tagatatgga cgaatcaatc cagataatcc
     1861 gtggtgcgta tcaccaccac ttaaaacaat ttttcccaga cctttcatca cgatatataa
     1921 aattatgccg ccaatcaaaa aagcgatcaa tacagaaggg ccggcgattc caatcgcttc
     1981 gccacttcct ttaaatagac ctgcaccaat cgctccacct aaagctagca tggtgatatg
     2041 tcgggagcta agttgttttt tcaatttttt atcttccata aataacctct ttcttttaaa
     2101 ttcacaatca aaatgcatag taagaataaa tagtaagaat aaatagtaat aataataatg
     2161 actaatgata acaaattttc agataattac aactattcag aaaacttttg ggcatatttt
     2221 aatggaagaa tgatttattt catcgtattt tcatagaaat gttaaatttt tataaaaata
     2281 ataggaagcg ttttactggc tttttactat ttaaacaggc tatcatagga aaaagtgaca
     2341 gagaaagtga ggcggaacag atgaacaaaa acgacgtatt gctaattgcg aaaaataaat
     2401 cactttattt ttttccttcc atccgctctt tagatgtttg gtccggaaaa gatttactac
     2461 agtcggaatt cattaaatca gctcgacaac agttggcaaa ttatcagctg atcgtttttt
     2521 tagattatgg atttgatatg gagatggctc gacgcgtgcg tccatttacc aatgcaaaaa
     2581 tcgtgttatt tttttggaac cactttaaag cagaacacga ggcgatgctg aagcaggcac
     2641 aagatgaacc ggcaatcgat gagatttatc attttgattt tttagaagcg aaagaacttg
     2701 gactaaaaca taatagttcc ttttattcga aacatatgga tttttcttct agcgaaccaa
     2761 agacggatct attttttggt gcaacaaata acggcagaaa agaacgggca gaaaaatata
     2821 agcaggaatt tacaaaaaga ggtgttacga ccaattactt tattcttccg cttcgaggaa
     2881 atgaacaacc tggatacctt acttatgaag aatatctgaa aaaaaccggg gaatcgaggg
     2941 ggattctaga actgttgcgg gaagggcagc aaggagtgac tttgcgaacg tttgaatcta
     3001 tgtattttca aaagaaacta gtgacagata atcaagccat agctcattat cagttttatc
     3061 attctgaaaa tatttttttg cttcaagaac gtgatttaga tgaattaccg gaatttttgc
     3121 atacgccatt tcaaccaatc ccatcagaac tgttggaatt ttttgatgca gaaaattggg
     3181 caaaacgttt tttcactact gactccgcta tttatgaaca atatgaatac gatctttcct
     3241 ctgttaaaaa taaataaaag tgccaaccaa tcatagatga aaataaacaa gcgcaattct
     3301 tatggcaaca tgagaattgt gtttttcttt ttgaactttc atgggggtaa aaaaatgaga
     3361 accagctgct gatccagctg attctcatca gagagccttt tattctgcgc caaggattcc
     3421 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     3481 ttgtcctttt cgccaaacgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     3541 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     3601 agcaatatgt tggtacactt cttcttgatc taatgtgatt ccttcttttg ctgcgataga
     3661 agcaaactca gatacaatcg ttcgaaccat gccctctgcc gctttttgcg cacctaattc
     3721 agcaatatta caatccaata tcgtgcataa tccatttaat gttccgttta cacaagcttt
     3781 tcgccaaatg gaataacgaa cattatgact atagattgga ttcaattttg cttcttgaaa
     3841 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     3901 ttctccatca cctaataatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     3961 gatcccaaat aagatatttt tctttggtac atatttttcc agtacatctt catgacctaa
     4021 tccattcagt aaacacaaaa cataagtatt ctcagtaata atggattgga tcgaacgaaa
     4081 catatcatct aattgattcg cttttgtcaa ggctacgatc aaatccacgt gtttgttgct
     4141 ttcgatgatt tcttctggtg aatagattgg cagttttgca actacttctt tgccattaaa
     4201 gtcagcaatc aatccatttg tacgaatggc ttcaatgtga gcaggccagc gatcgatcaa
     4261 gacgacctca tttccgcttt gatgcaacat taatccgatt cggctgccca ttgctccggc
     4321 tccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     4381 tatagaaaaa cagaagaaaa tagcattgtt ttgtttgaaa aaagtgaaaa aaagtgtctt
     4441 acttaagaag aaagtgaggg atatagatgg atattttggc ggcaatcgat tcatttaaag
     4501 gaagtgcttc ttcatttgaa ttaaatcagg cagttctaaa tggttgggaa gaccgtaaag
     4561 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     4621 acgcgctcgg gggaacctgg cgtacgattg atgggatgga tctcttattt cgtcagcgaa
     4681 aaatcagtta tttattgacg aactggcaag gaaaaaatac cgcagtcatt gaatctgcac
     4741 aagtattagg attagattta cttgataaac caacggatca aaccatccga cttgcttcta
     4801 gttatgcctt gggagagctt atcaaagata cactgcttca agaagtggaa caaatcattg
     4861 tcactttagg aggaagcgga tgtagcgatg gtggtctagg attactccaa tctttgggtg
     4921 cttctttaga agggtacaca gaaggaaatc ctttgttatc tactagaaaa cttcatttgg
     4981 atcgaaggaa cgttcttgtt tctaaagtaa aagtgatcat cgctgcagac gtgaccaacc
     5041 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaacggata
     5101 cgacgttagc tttcttggat aaacaagctg aaaagattgc tcagcagata aaagatgttt
     5161 gggaggtgga tttagatgac atcccaggaa gcggagcagc aggcggtatt ggcggagccc
     5221 tttttttgtt aggagcgaag atggtctctg gttttgagtt ggtcagccaa atcactggat
     5281 tagaaaaaca gatcgaacaa gcggatgtca tcattacagg agaagggcgg attgatcagc
     5341 aaacaatcca cggaaaagtt ccatatggcg tagcagtgct tgcaaaaaaa tatcgaaaac
     5401 caataatcgc tatttgcgga agtagagacc gagagctgga aggactcttt gattttctcc
     5461 ccattgtctt aagcattcaa ttaggaccaa tcgatttaga ggaagcaatg gaacacaggc
     5521 aaacattaga aaaaacagaa atcttaggac agacactcag cagatttttc aacattctcc
     5581 cgaagtagtt gacaaaaaca atttctttat gctatcgtaa tttcaaatat aggacaaagt
     5641 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     5701 tgtggagaca agggagcagt gtgcagattt tcgggattgg cttggttctt tcgatgtatg
     5761 ggtctttttg tgtgccccaa cccttgcatc ctctttagcc agttctgaaa ataggactgg
     5821 tcttttttta cgaggtgatg gaataatgtc taaaatcgaa ataaaaaatc tgacattcgg
     5881 ctatgacagc caaggcacat tattatttga acaagccaat ctaaactttg acacacaatg
     5941 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atatcctgca
     6001 aaacaaactc ccttatcaag ggcaagtgat ccatcagcaa gcgtttgtct atttcccgca
     6061 gcaaacaaaa gataaagagc gtttgaccta ttatgtgtta aatgagatta tggattttga
     6121 gatatgggaa attgaaagag agctccaact gatgcaaaca gatcctgaaa tcttatggag
     6181 agaattcagc acactatcag gaggagagaa gacaaaagtc ctactggcac tcttatttgt
     6241 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggcag
     6301 aaaacaagta gcggcttact tgaaaaagaa aaaacaagga ttcatcgtgg tgagtcatga
     6361 tcggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaga gccaactgga
     6421 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     6481 aatagctaaa aatgaaaaat tgaaaaaaga agtcagcagg ctaaagaaaa cagcagctga
     6541 aaaagcagaa tggtctcgtt cccgagaagg ggacaaaaca aagaaaaaag tcggattcat
     6601 cgatacggaa tctaggcgag tgaataaagg agcagtaggc gctgatgctg cacggacgat
     6661 gaaacgatct aaagcaatcg tgaatcggat ggaaacccag atcagtgaga aagaaaaatt
     6721 attaaaagat atcgagtata tcgatgcttt gacgatgaat agccaagtgt ctcatcataa
     6781 acggctgtta agcgtagaaa atcttcaatt agggtatgaa aatctgttat tcgagccagt
     6841 tcattttacg atcgaacctc atcagcggat ggcaatttca ggtcctaacg gcgcgggaaa
     6901 gtcatccatt atccattatc ttctggggac attcaacggc aaggttgtag gagaaaaatc
     6961 ccagcccaaa catttgacca ttagttacgt acgccaaaat tatgaagaca atcgagggac
     7021 attggcggaa ttcgcgaaga aaaaccgagt agactatcaa gcatttttga ataatctccg
     7081 aaagcttggg atggaaagag atgtttttca taataaaatc gaacagatga gtatgggaca
     7141 acggaaaaaa gtggaattgg ctaaatcttt atcccaacca gctgagctct atatatggga
     7201 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgattttgaa
     7261 cgtgaaacct gctatgttac tagtggaaca tgatcaaacc tttctagata aagtatctac
     7321 tgagattatt tctcttgaga aaatctaaac cttgtaatct caaagacaac aaggtatggt
     7381 taaggagaac tttgtcaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     7441 aacaacttgg aacgcacaag gattagtttg cgggcgagca gatgtgccgc tgactgaaaa
     7501 aggacagatg caggcacagg cactagcaga aaaggtagta gatttgcctg ttccaatcac
     7561 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag tagttgatcg
     7621 tctcaatttg ccgatgaccg ctgatgagcg attggtagaa atggattttg gggattatga
     7681 cggactgcca agcaaagatg aaaactttca aaaagcgcgt ttagcgtttg ctgtacgttt
     7741 cccaaatgga gagtcggtct tagatgtgta cgcacggatc gttcctttat tgaaagaatg
     7801 catggaagac gaagaaaatg tctacttgtt agtctgtcat aatgccttga taagagtgat
     7861 caatgcttat tttcatccaa tgcctaatga agggttcttt acattcatgg tagacaatac
     7921 agaattaatt tcttatgagt aattagactt ttgtgttatt taaataaaat gtttcaaggc
     7981 actgcttttg cttagcagtg ccttttttgt ggctgtgtca attcttttgg cattataaat
     8041 ccaattttta gaaataaaat ttaattattt taacaaaagt attgaaattt tgtttcttta
     8101 gatatatact ctagtcatag aaatgaagac ggatacagaa aaagagggat aatatgtttg
     8161 gcttttcaat atttatgaat gattctttgt cagaagagaa gaaacagtat atccgccaaa
     8221 tggcatccaa tggctttgtc ggtattttca cttccatgca tataccggaa gatgatgttt
     8281 cggcttatca aaatcgattg atcgaactag gaagcgaagc gaaaaagaat aaactagagt
     8341 tgatggtcga tatttcagga gaggcattga aacgagctgg cttttcatta gaagatctaa
     8401 cacccttgaa agcaattggt gtaacagggt taagaatgga ttatcatatt tctaatcagc
     8461 agatcgccga ctggtcacat caattgaaaa tcagtttgaa tgccagcacg atcacgccta
     8521 atgatatcga tgagttgaaa gaagcagcgg ctgatttctc acagattgaa gcttggcata
     8581 attattatcc acgtcttgaa acagggttgg acaaagaatg gtatcaggaa aaaaatcaat
     8641 ggctcaaaac tcaaggattc cttgtacaag gctttgtacc aggagataca gagttgagag
     8701 gtccactgta tcaaggatta ccaactttgg aagaacatcg agggatccat cctctggcag
     8761 gtgctcttga tctattagca agtaacacgg atattgttta tatcggagat gcaggtctgt
     8821 cagaacacgt tcaggagcaa tttgcttctt tccaaaaaga acagacagtc ttgctccata
     8881 cggaacctgt agatgaagtt ttttacgaat atatattagg aaaacatacg aatcggcaag
     8941 atgatgcaag agatgtcata cgaagcgcag atgcgcgttt tcgagagatt ccgccaatcc
     9001 cagtaagaaa tacagctaag cgtatgaaag gatctattac tttagataac gaaaagtatt
     9061 tgcgctatat gggtgagatc caattaacta aatatgattt gccagcggat gaaaaagtga
     9121 atgtagtagc caaagtcatc aaagaagaac taccgctgat caaccaaatc aaagctggta
     9181 tgaactatca atttataaga aaagaaggaa gataaaaatg agcaaaatca atttagagaa
     9241 cctaacaacg gaacgcagaa accaagaaac ttttggatta gatgaaatga gtatttctca
     9301 agcagtccaa ctcatgaaca aagaagatca gaaagtggcc gctgctgttg aaaaagaact
     9361 gccaagtatc gagccagtga tcgccaacac gattgaatcc tttaaaaaag gtggtcgctt
     9421 gatttatatg ggagctggaa cgagtggtag acttggtgta ttagatgctg ctgaatgtgt
     9481 accgacattc ggtgtagaac cggaaatggt cataggccta attgctggtg gagaagaagc
     9541 aatgactgta gccgtcgaag gagccgaaga ttcttatgaa ttagggcaag aagatctaat
     9601 caagctgaat ttaacaaaaa atgatatagt tattggtatc gcagctagcg gtcgtacacc
     9661 atatgtgatt ggtggattag attacgcaaa atcgattggt gctgttacag gaacgatttc
     9721 ttgcaataaa caagcagaaa tcagcgagca tgcggatttc ccaatcgaag tcgatgcagg
     9781 accagaattt ttgacaggct ctactcgatt gaagtcagga acagcacaaa aactgatttt
     9841 gaatatgatt tctactatca gtatgatcgg tatcggtaaa gtattcaata acttgatggt
     9901 cgacgtcaaa ccaacaaatg aaaaactaat tgaacgctca aaacgaatca tcatgcaagc
     9961 gacagaagct gactacgaaa cagctgaaaa gtactttgag gaagcagatc aaaatgtcaa
    10021 actggctatc gtcatgattt tgacaaatag tgataaagag gcagctcaag caaaattagc
    10081 tgaagcaaac ggttttgtaa aaggaacctt atgaggggga aaagaccatg gcaaaaaacg
    10141 aattgacttt ggaagaactg gcaaaacaaa tttatcaagg agcaggcggt atgggcaatg
    10201 ttgaaagcat tgtccactgc atgactcgtg tacgtatgaa ggtcatcaat gatgatcttg
    10261 taaatgtctc ggaattaaaa gcgattccag gagtacttgg cgtagtagag gatgaacagc
    10321 tccaagtcat catcggacct gggaaagtga acaaagtagc gcaggaaatg gttgacttag
    10381 caggcgtgaa attaggagaa aaacttcctt ctgctagtgc aactacagca agttcttctg
    10441 catctggaaa agaccgtgta aacgaacggg cacaagaaat gaaagcggca caaaaatcga
    10501 aacaaaaacc ctctaaaatc aaatcggtat taaaagacat ctctaatatc tttgtaccaa
    10561 tgatccctgc atttgtcggc actgggatcg tggcagggat tgccgcagtt ttagcaaact
    10621 tagtcacagc tggaacacta gacgcaggaa catggcaaca atatatcgat gtgatgaaca
    10681 tcttgaaaaa cgggatgttt agctatctag ttatctatac aggtatcaat gctgcacaag
    10741 tttttggtgc aacgccaacg cttggtggag ttatcggggc tgttgtgatg ctgacaggga
    10801 tgaatccaga agcaccactg aaaaacttgt ttaccggtga agctcttgca actggacaag
    10861 gcgggatctt aggtgttatc ttcgcagttt ggttattgtc aatcgttgag aaaaaactgc
    10921 ataaagtagt acctgatgcg gtagatatca tcgttacgcc aactctttcc ctgattgcca
    10981 tcggtctgat cgaaattttc ttcatcatgc ctttagcagg gttcatttct gacggcatgg
    11041 tcggtgggat caactgggta cttggtgttg gaggagcatt tgccggcttc gttctaggta
    11101 cattattctt gccaatggtc atgttcggac tacatcagat cttgacgcca atccatgtac
    11161 aaatgattga tgaaactggt cgtaccttat tgcttccaat ccttgcgatg gccggagcag
    11221 gacaagtggg tgcagcattg gcattatgga tccgctgcaa aaaagacaaa gaattaacag
    11281 aaatgatcaa aggggcttta ccagtcggaa tcttaggaat cggcgaacca ttgatttacg
    11341 gagtaacatt acctctagga cgtccattta ttactgcttg tatcggtgga ggtatcggtg
    11401 gggcagtgat cggaatgatc ggaaatgtcg gagcaatcgc tattggacct tcaggagccg
    11461 ctttgattcc attgatctct gatggtaaat ggttaggcta tatccttggt ttattggctg
    11521 cttacgctgg tggcttcgtt gctacattct tcttcggtat tcctaaagac cgtttagaaa
    11581 aagaagaact agcgaccgaa acagccacag taaatgaagt acctgaaaaa gcagtacctc
    11641 aagcttcagc tgaaagtgtg actatcttat catcagttgc tgacggaaca gttgtttctt
    11701 tagataaagc aagtgaccca gtttttgcac aaaaaatgat gggtgaaggt tactttgtag
    11761 aaccagaaaa cggacatatc tattccccgg ttactggagt aataagttct gttttcccaa
    11821 caaaacatgc tatcggcatt acgacaccaa atggcttaga aatcttgctt cacatgggca
    11881 tcaacacagt tgacttaggc ggtacgccat tcgatgtgaa agtaacagaa ggacagcaag
    11941 tgacacctga tacgcttgta gcagaagctg acttagaagc aatcaaagca gcagacaaag
    12001 aaacctccat gatcgtcttg gtaaccaata tggatcgtgt aaaaaacttt gtcttggaaa
    12061 aaacaggtaa agcgaaagca aaagcacctg tgatggatgt caaagcttaa taagaataga
    12121 aacaatagag aacataaaaa gaagaagccg aaatttattt ttcagcttct tcttttgtgt
    12181 tatttatttt tttctgccaa aatttgataa acgcgtgtca catcagatgg tgttccccgt
    12241 aattcataat ctgccaagaa aggaaagccg aatctttgtg cgtattgttt ggctgtcaga
    12301 caatattgat tgttgaagtt tttattaccg ctaccgacta caccaaggca aagtttatga
    12361 ttgtcttcgt attccagata ttcgcgcatc gtttcggtca agatttctgt gtcaccgttg
    12421 tctaacccat tcccgccgtc taaataagta ggaacgaaag taaaaaatgg ttctgtttct
    12481 ttcgtaaaat cactattttc atggatttct tttaaagtaa cttcaggatt gacaggatct
    12541 tctgcatgca ttttttcagc atattctgct agatgtttgg caaaagcacg cgtatttcct
    12601 gaaatcgata tatataaaat gttcatggat catcccccaa ttctttccct ttagtatagc
    12661 atctttttaa gtttttttgg tggtgtaatt tggaaaggga ctaggcgctt tgcttgtata
    12721 atgagaaaaa agtcggtaga attatatttc tattaaagtt tttattaatt aagtaaaaat
    12781 aaaaaaggtt tgttatactt tttgataaaa gcggttttac tttggaggat gcttacatgg
    12841 atacagagca acagaaaaaa ggaattggtt tgattccact tgctgcctta gtgattggtt
    12901 cagcgattgg aggtggcgta tttggtatta tgacggacat ctccggatcg gctggtggcc
    12961 cagctatctt cagctgggta ctcgtaggaa cagcaatgtt gatgctctcc ttatcgatca
    13021 ataatatcaa taaaaaacgt ccagatttaa aaggcgggat ctttagttac gcagaagaag
    13081 gttttggccg tttcgctggt tttatcagcg gttggggtta ctggctcaca tgctggttag
    13141 gaaacgtggc gttcgcaaca ttgttgatga gtgcattagg ttatttcttc cccgtattcg
    13201 aaggtggtca aaatgtggca tcgatcgtga tgagtacgat cttcttatgg ggatatgcat
    13261 ggctagtgaa tcgtggagtt gaaaatgcta gctttgtcaa tgctatcgtc acattttgta
    13321 aattagtgcc attattttta tttattgtag tagctatcag caccttttcg atccaacaat
    13381 tcattaataa cttttctagc gatatcatat tgaatgcgaa tgggcagccg atcccgtttt
    13441 ctagtcaagt attgagttgc atcatggtga tgctctgggt attcgttggt attgaaggag
    13501 cttctgtcgt aggttcacga gcaaaaaaac aatcggatgt tgggaaagca acgattctag
    13561 gaatattcgg tttgatcatt atttacgtct tggtttccat gcttccatat ggcacaatga
    13621 cgatgaatca gctgcaaacg atcaaagcgc aacctgctat gggatatgta tttgaaatga
    13681 tggttggtaa atggggggcg gtcgtgatca acggcggttt gatcatttct ttagttgggg
    13741 tttggctctc atggacaatc ttgccgattg aaacaatggg gaatatggct gaggacggac
    13801 ttttgcctaa agcatgggga aaactcaaca aaaatggggc accaacttat gctatcgtat
    13861 tgacgacgtt atgtacgaat gtctttttac tttcattatt attcactgac agtgcatata
    13921 actttgctta tacacttggt acagcagcga ttttcttcac gtggcttttc ttagggctgt
    13981 accaaatgaa gctttcttat cagcggaaag agtgggtcca atttttagta gggtttttag
    14041 caagtgcttt tcaagtatgg gccatgctag ttgtagcctt taatgaagtg atgcttgttc
    14101 ttgttctttt cttaccaggt atttattttt acctcaaagc acgtaaagaa caaaacgaac
    14161 ctgtacaaca tatccactta gataagattt tacttatcgg tgtgacgatg gtcggagtaa
    14221 tcgcaatggt tttatttgcc actgggatgc ttcacgtata gaagtataaa gagaggctgt
    14281 gaagcctgtg gtttattcaa aaaagaagcg gtgacaacat tcgtgtcatc gcttcttttt
    14341 ttgaataaat ggtgttcaag aagtagcttc ttctaaaaat aagccgaaat ttcttgaaac
    14401 tggccacttc tgtcacaact tctttgttaa tgaaccatca tacatttttt cgcttgaata
    14461 cgaggtatcc caatgctaag aacaaagcaa tgtaagctaa attgccaaac agcatttgat
    14521 tagtagaaag atgagtcaat tgcttcataa tctcttcgtt gccaatttgg ttttgcagat
    14581 tcagcatact gattggattc catttgatcc actcccattt ttgaatgagt gcgatgagga
    14641 taccagatat gattgatgaa gcaaaataaa agacgatccc tgctgagatg gaggcaccgg
    14701 aactattgat aaaacaagca atcatcaaca ctaaacttaa aattagccat aaaccgatat
    14761 aactacccaa agtataagtg aataagcttt ggatcagtgt ctgaccagta gaaatcttct
    14821 ccgtaaagga aatcgaaggg aaaaggatca gtttcatcag cacggtgaca ataatagcta
    14881 aaaggtataa ataaatagaa taaataacta atgtgatcca tttacttact aatatttctc
    14941 ctcgagaata ctttcgataa aggagatttt tcaatgtacc atattgtgat tccattgaaa
    15001 tgatcgtact tgcagcagca atcatgataa agacaatcca agatgtggca ctgaaaagct
    15061 gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt tttggctaga agtgctgttc
    15121 ctatgagcaa agcaactaat agaacagata aaacagcagt tgactttttc ttgatcaatt
    15181 taaataattc ttgttttata agcaacgtca tttttcttct tcccccttta ctgaatccag
    15241 aatttccaat agggaagatt ccaaatcatt cgtcagatgc tggacatctg tcacatggac
    15301 attttctgca gacaataact ggataacagt tcctaataac tcttcgtttt tttttagaag
    15361 cttgatttta tcaggatctt ccaagggata tccagcgtct gtcaagatcg ttcgagcagc
    15421 ttgatcattt gtcgtagaga taacgatgaa atcttgcgct gtttggttca attcagccat
    15481 tgtacattgt ttgatgattt ttccttgatt gatcaggatc agctcatcga ccattttttc
    15541 aagctcgctg agtaagtgac tggagatcaa gaaagaggtg ccctgagtag ccaagtcggt
    15601 aatgattttt cgcacatctc ttgttgcttg tggatccaaa ccgttcatcg gctcatctaa
    15661 aataacgata gacggatggt tcagtaaggc aagagcaatt cccaattttt gtttcattcc
    15721 cagcgagtag gatttcgctt ttttgtgaat gtatttttcc atcttgagct gtttcacgat
    15781 agtgtcgata gcagatacat cgtttgtttc agagaataac ttcagatgat cataacctgt
    15841 taagaatgga tagatacccg gatattcgat caatgctcct acttgttcta atcctttatg
    15901 actagaggga gaaatctcat tttcaccaat acggatcgtt ccttctgagt aatggatcag
    15961 tcctaaaata gctttcatga tcgttgtttt tccagcgcca ttaggaccta ctaatccaac
    16021 gattttgcca ggagataagc taaaactgac atcgctgagg gcttgtttgt gaccaaagtt
    16081 cttggataat tcttggaccg aaagactttt caaaaatatt cactcctttt ctatagatag
    16141 tacaagcata cacctgatga gtagagaagt cgctaggtca ttagtcttat tttcttgttt
    16201 tttcatagaa agaggaatat caaataaaaa gccccgcttt ttctgatcag tccttgtctg
    16261 cttgtctaag tatctagtga ccgctagtga ttttgatgcc aatgatgctg atgagcagca
    16321 acccgacaaa gaaccaagtg gaaagattca gcttatcatg aaacaagacc acaccaataa
    16381 tgaccgaacc aactgcgcca atccctgtcc aaataggata agagagactc ataggcaaac
    16441 ttttgattgc ctttgacaaa aagtaaaaac tagcaatcat tccaatcact gtgtaaaaag
    16501 aataattgat tttagaaaaa ccatcactcc atttcatcat cgttgaccag aatacttcca
    16561 aaattcctgc tatgattaat tccatccatg ccatacatac gttcctcctt caatataaaa
    16621 aatacacaaa aagaggagaa tcatcccttc aaagacctaa tggaatgatc atcctctttt
    16681 ttactacccg gtggcagatc gtatatcttt ttctgtagta tagcacacct atccagatat
    16741 cggcaatctc atacttttta gtaaagtgta acaagcattg acggatatat cgttagcaga
    16801 aaagaagatg aatgctttgc aatttcatag aaaggagttg ttatttatta atcatttaaa
    16861 aaaacagtaa ctagacctta tttttatata ttagcaggca ataaattaaa aaaagcttta
    16921 tcttacaata agtaaggtga attatataat aaaaaaataa cgaaaaatat ttaaaaatag
    16981 tgtctatttc gtgagaaaac aactatattt tttatgtgtt ttgctttata attaaaaaaa
    17041 tattgtcatt ttatggagga aaatatatgg aaaattatct tagcctttta ggcgtcttga
    17101 ttgttattct cgggtttgca tttaaattag actcgatatt gatcgtaatg gttgctttag
    17161 ttgttacagc tttgactggc ggtcttggca ttcaaggaat gttagaactt ttaggtacaa
    17221 gttttgtaaa caatcgcggg atggcgattt ttatcatcat tatgttggca acaggaacgc
    17281 ttgaaagaaa tggtctgaaa gaatcagcgg cttccttgat caagcgattc aagaaagtat
    17341 ctgctggtat gattgtagat atttatggga tctttcgaat gatctttgcg gcttttaacg
    17401 tgagttttgg tggagttgct ggatttgttc gtccaatcat tttaccgatg gcattgggga
    17461 ccatcgaatc aaaagggtta gaagtccatc ctaagcatga agaagaacta aaaggtatgg
    17521 cttcagctat ggaaaatgtc tgctggttct ttggccaagt actattcatc ggaggagcag
    17581 gggcgttgct agtccaatca acactgaaag atctaggata tgacgtaaca ttgggacagc
    17641 ttgctttagt ggaagttcca gtggctatca cggctttagt tgtggcaagt gtctacttct
    17701 atcttaaaga aaagaaatta gcgaagaaat attatccagg aaaggggcaa taagatggac
    17761 ttttttacaa atcctgatat tttattaggc gataaattac tggagatcct ttatatcgtg
    17821 atgggactcg tattgattta cactggagta agaaatttaa cagataaaac caatcctcat
    17881 cgttatgggt cagccttttt ctggacggtc ttaggggtag ttattgcagg aggaagatgg
    17941 cttccggcaa tcgtgaacgg tggcttgatc tttgcgatga ccataccagc aattgctaag
    18001 aaagtcagca aaggagaaag ccggcttcca tcaaaagaat atatggaaaa aatgtcagac
    18061 aaactaggaa tgaaaatttt tattccagct ttgagtatcg gtgtctttgc gatcttgttt
    18121 gctctattta ccaatttagg tgctttagtc ggcgtgggcg tcggtgtttt tgcagccatg
    18181 ctaatcttga tgttcttttc tcgagataat cgaccaagta catttttaga tgatgcagca
    18241 gatatgctgg gcacagtagg gccgttaagc atgttgccaa tgcttttagc ttctctaggt
    18301 gcggtattta caagcgctgg agttgggaca gtgatttcca atgcagtagg tacgatcgtt
    18361 ccagaaggaa atgtgaacat cggcatcatc atttacgctc ttggcatggt gatatttacg
    18421 gtaatcatgg ggaatgcatt tgcggccatc accgtgatga cggttgggat cggtgcacca
    18481 ttcgtattta gtcatggagc gaatccagcg ttaataggaa tggttgcatt gacttgcggt
    18541 ttttgtggga ccctgctgac accgatggct gctaacttca atatcgtgcc tgtagcgatg
    18601 ctggagatga aagacaaata cggagtgatc aaaaaccagt tgtttattgc gttatttatg
    18661 ctagttttcc aaattgctta tatgattcta tttaaataat agaagagagg ggttgtgaca
    18721 gaataattgt cgcaacctct tctaacattg tagtggaaca ctattttttt ataagaatat
    18781 attaagtttg atctgttatg ttatttaaac tattgtttcc tttatttacg ctgttcaagg
    18841 aaaatggtat gataaaagat aaccatatgt taaatcaatc ggacggagga acaacagatg
    18901 aaagtactag taacaggttt tgatccattt ggtggggaca aagtgaatcc agcctatgaa
    18961 gcagtaaaaa aaatgccaga tgaaatcagc ggtgctgaaa tcatcaaagt ggaagtaccg
    19021 accgtattcg aaaaaagcag tcaagtagtc aaagaagcca tccaacagca ccaaccagat
    19081 gtcgtgatct gtgtcggaca agcaggtggg cggtcagcag tctcgttcga acgtgtcgca
    19141 atcaatctag cagaagcaag aatccctgat aatgaaggaa atcagccatt cgatacggct
    19201 ttagaagaaa acggtccagc cgcttacttt acctcattgc caatcaaagc aatgacaaaa
    19261 aatgtacaag atcatggtct accagcgtac atctcttata cagcaggaac atttgtctgc
    19321 aatgatatca tgtatcgttt gcttcatttg atcgaaacac aattcccggc aattcgaggt
    19381 gggttcatcc acgtgccatt ctcacccgat caagtgatcg atcgtccagt gggtacgcct
    19441 tctatgtctt tagaagacat tgcttcttct ttgacttatg cagttgaagc agcagtagaa
    19501 aataaagaag atatttccgg aaatgccgga acaactcact aatttagcaa gaaacactgg
    19561 ctggttgcta acgttatgtt agtagccagc tttttgtaat tagaaaggaa agaaacagcc
    19621 gtggaagaat ggcaatccgt ctttgaagaa tggtttccaa aagaaatcag caaaagctat
    19681 cccatcaaaa tttctaaaca atacacaagc agtcaacgtt gggagatcta tgcaaaatta
    19741 acgaaaaaac agcgggaact agtcgataag caccgccgat atctaatcag ctctcgtttt
    19801 atggaagaac attatttagc tgcaacagat tgggtgtttt ctgacttcaa gatcaatccg
    19861 ttttttcgaa caaaacgaag ccagcaaaaa ttgtattgtg agtgtggtag agaattaaaa
    19921 gtgcaataca tcgttaaatc gccaaaaacc ggaaagatcc taaaactagg catcaaccac
    19981 tttgccgatc acctgcatgt ctctccgaca gtggcagctt cgatccatca gggaatgaca
    20041 aaagttgatc tggccttaga cgaattatta tggcttaagc agaagaatat cgattttcct
    20101 gaaggactat ggcaaaaata ctgttttgtc ttgtaccaaa atcgtcggat gaaacagcca
    20161 tatttaccgg atataaaatt agctcagcgg ctcgcagaat ttcgccaagt agaaatgccg
    20221 atttacatag cggattatca agcattggaa aatgaaatca agaaaataag tgaacacatc
    20281 aatgggcagt caaaaaagcg acagataaaa aaagaactat ttgacgactt tgcagaagaa
    20341 ttagtaaagg atgtagaaga attcttgatc aactatcgcg catttttacg taaagattgg
    20401 caatccatcg tatatgaaga agtgccagta catcctaatg cttattttga aacatttatt
    20461 tccgtgttga gaaagacaaa acgtcaacga acaccagaag tcactgctca gatggaatat
    20521 tttgcgaaaa accaacgatt catccaacca aaaatctatc tatttatttg gaagcaatat
    20581 tgtcgctatg gttttacaga agggttcttc gacagcattc ctcggatagt cagaaatggt
    20641 tttttaaaag tattgcgtaa agaacgagaa gctatacaat ctgctgataa gaaagaccgt
    20701 acagtctcaa aagaaaaatg gcaactagta gtgaaagata tccaatctgg aaatgtgcaa
    20761 gagacaatcg acaaatggaa aggaaaacat tatcgtttta ctgaagctca gaaacaagcg
    20821 ttggaatatt atcagaagtt agaagaatca ctgcgtttca atgatgaggc aagaaagtat
    20881 ctgaaggaat tactataaaa aatagaggct gggacagaag cgtttaactc caagaaataa
    20941 gaa
//
LOCUS       DACGLI010000202        13213 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.076, whole genome shotgun sequence.
ACCESSION   DACGLI010000202 DACGLI010000000
VERSION     DACGLI010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.076"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(204..2162)
                     /locus_tag="IXT22_003091"
     CDS             complement(204..2162)
                     /locus_tag="IXT22_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4864368.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="IXT22_003092"
     CDS             complement(2159..3031)
                     /locus_tag="IXT22_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4864369.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="IXT22_003093"
     CDS             complement(3373..4245)
                     /locus_tag="IXT22_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4864370.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="IXT22_003094"
     CDS             4373..4942
                     /locus_tag="IXT22_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4864371.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="IXT22_003095"
     CDS             5009..5746
                     /locus_tag="IXT22_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4864372.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="IXT22_003096"
     CDS             5977..7245
                     /locus_tag="IXT22_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4864373.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="IXT22_003097"
     CDS             7732..8196
                     /locus_tag="IXT22_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4864374.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="IXT22_003098"
     CDS             8180..8809
                     /locus_tag="IXT22_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4864375.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr"
                     /locus_tag="IXT22_003099"
     CDS             9163..10641
                     /gene="msr"
                     /locus_tag="IXT22_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4864376.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="IXT22_003100"
     CDS             10688..11134
                     /locus_tag="IXT22_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4864377.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="IXT22_003101"
     CDS             complement(11333..11848)
                     /locus_tag="IXT22_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4864378.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="IXT22_003102"
     CDS             11965..13167
                     /locus_tag="IXT22_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4864379.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DACGLI010000203        12200 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.079, whole genome shotgun sequence.
ACCESSION   DACGLI010000203 DACGLI010000000
VERSION     DACGLI010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.079"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            14..238
                     /locus_tag="IXT22_003103"
     CDS             14..238
                     /locus_tag="IXT22_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864380.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            355..852
                     /locus_tag="IXT22_003104"
     CDS             355..852
                     /locus_tag="IXT22_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4864381.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            939..1331
                     /locus_tag="IXT22_003105"
     CDS             939..1331
                     /locus_tag="IXT22_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4864382.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1315..3762
                     /locus_tag="IXT22_003106"
     CDS             1315..3762
                     /locus_tag="IXT22_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4864383.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3765..5948
                     /locus_tag="IXT22_003107"
     CDS             3765..5948
                     /locus_tag="IXT22_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4864384.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5945..6946
                     /locus_tag="IXT22_003108"
     CDS             5945..6946
                     /locus_tag="IXT22_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAQ4864385.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6961..7875
                     /locus_tag="IXT22_003109"
     CDS             6961..7875
                     /locus_tag="IXT22_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4864386.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8120..8236
                     /locus_tag="IXT22_003110"
     CDS             8120..8236
                     /locus_tag="IXT22_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAQ4864387.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            8252..10171
                     /gene="tet(M)"
                     /locus_tag="IXT22_003111"
     CDS             8252..10171
                     /gene="tet(M)"
                     /locus_tag="IXT22_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAQ4864388.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            10269..11642
                     /gene="tet(L)"
                     /locus_tag="IXT22_003112"
     CDS             10269..11642
                     /gene="tet(L)"
                     /locus_tag="IXT22_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAQ4864389.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         3817 a         2182 c         2564 g         3637 t
ORIGIN      
        1 tgagatattt ataatatcag gaacttacct atccatatat aactggtttc tatcaaacgc
       61 tcaatcactg gtgcttttag caatcgttgt gattggcttg tatcttggct tcaagcgtga
      121 gtttagcaaa ctgattggct ttttaattat tgcgattatt gcggttggct tagtcttcaa
      181 cgctgctgga gtaaaagaca ttttactaga gctattcaat cgcattattg gtgcttaaat
      241 aaaaccgttc ttttgtggaa tataagtggt tttcttatgt tccgcaaagg aatggtacac
      301 caaacgaagt gcggtaggga tttttgaatc tctacaaaga aaggacgtga atatatggac
      361 gatatgcaag tctatattgc gaatttaggc aaatacaatg agggcgaatt ggtcggtgcg
      421 tggtttacct ttcccattga ctttgaggaa gtcaaagaga aaatcggctt gaatgatgaa
      481 tatgaggaat acgccattca tgattacgag ttacccttta cggttgacga atacacttct
      541 attagcgaac tcaatcgcct atgggaaatg gtatcggagt tgccagaaga actacaatcg
      601 gagctatctg ctctgctcac tcatttttca agtattgaag aactaagcga acatcaagaa
      661 gatattatca ttcattccga ttgtgatgat atgtctgacg tggcacgcta ctacattgaa
      721 gaaacgggtg ctttaggcga agtgccagcc agtcttcaaa actatattga ttatgaatcc
      781 tatggtcggg atttagacct ttcgggaacg tttatctcaa ccaatcacgg gatttttgaa
      841 atcgtctatt aaatctgtcg gtacattctt actggcagat tttcttgttt acggggtagt
      901 caaaagacta tccccatttt tatgaaagga ttgattacat gaagaaaata cgaagctata
      961 ccagtatctg gtctgttgag aaagtgttgt actccatcaa tgactttaga cttccgtttc
     1021 ccataacctt tacgcaaatg acatggtttg tcgtgtcact ctttgcagtt atgatacttg
     1081 gcaacttgcc ccctctttct atgatagagg gagcatttct caaatacttt gggattcctg
     1141 tggctttcac atggtttatg tctacaaaaa cctttgatgg taaaaagcct tatggatttt
     1201 tgaagtctgt cattgcttat gcactgcgac gaaagctgac ctatgcagga aaaaaagtaa
     1261 cgcttggcag aaaccagcca caagaagcca ttacagcagt taggagtgaa ttttatggca
     1321 tatccaatta aatatattga aaacaatctg gtctggaata aagatgggga atgttacgct
     1381 tactatgagc ttgttcccta caattactca tttctaagtc cggaacagaa aatacaagta
     1441 catgattctt tcagacagct tatcgcacaa aatcgtgatg gcaagattca tgctttacaa
     1501 atcagtacag aatccagcat actttctgca caagaacgtt ccaaaaatga agtcactgga
     1561 aagctcaaaa cggttgccta tgacaaaatc gaccaacaga cagacgcttt aatatccatg
     1621 attggcgaaa atcaagtgga ctaccgtttc tttatcggtt ttaagttgct tctcaacgat
     1681 caggagtttt ctatgaaaag tcttaccgtt gaagcaaaaa atgcttttac tgattttgtc
     1741 tatgatgtga accataagct gatgggcgat tttgttagta tgagtaatga tgaaatcctg
     1801 cgttttcaga agatggaaaa gcttttagaa aataaaatct cccgtcgttt caaaatccga
     1861 agattagata aggatgactt cggctatctg attgaacacc tttacggaca gacaggcact
     1921 gcctatgaag agtatgagta tcctctatca aagaaaaagc tggaacatga aacactgatt
     1981 aaaacctatg acctcattaa gcctactcgc tgtctggtgg aagaaaaaca gcgatatttg
     2041 aaaatccagc aggaagacga aaccgcctat gtagcttact ttaccatcaa cagtattgtc
     2101 ggcgaactgg acttcccgtc ctctgaaatc ttctactacc agcaacagca atttaccttt
     2161 ccgattgata cgtcaatgaa tgtggaaatt gtagcgaatc gtaaagccct atctactgtc
     2221 cgcaataaaa agaaagaact gaaagacttg gataaccacg cttggcaaag tgataatgaa
     2281 accagctcta atgtggcgga agctctggaa agtgtgaacg agctggaaac caatttagac
     2341 caaagcaagg aatctatgta taagctgtcc tatgttgtaa gggtatcagc aaatgacctt
     2401 gacgaactta aacgtcgttg taatgaagtg aaagatttct atgatgattt gagcgtgaaa
     2461 ctggtacgac cttttgggga tatgctgggc ttacatgaag aatttttacc tgccagcaaa
     2521 agatatatga atgactatat tcaatacgtg acctctgatt tcctcgctgg tttaggtttt
     2581 ggtgctactc aaatgctggg tgaaaatgag gggatttatg ttggctacag cttagatact
     2641 ggacgcaatg tctatctgaa acctgctctt gccagtcaag gggttaaggg ttcagtaacc
     2701 aatgcgttag cgtctgcctt tgtcggttcg ctgggtggtg gtaaatcctt tgcgaataac
     2761 cttatcgtct attatgcagt gctttatggg gcacaagcag tgattgtaga cccaaaagca
     2821 gaacgtggca gatggaaaga aaccttgcca gagatttccc atgaaatcaa tatcgtcaat
     2881 ctgacttctg atgagaaaaa caaaggctta cttgaccctt atgtaattat gaaaaatacc
     2941 aaagattctg aatcactggc tattgatatt ttgacattcc ttacggggat ttcctctcgt
     3001 gatggggaac gcttcccaat ccttagaaaa gccattcgtg cagtaaccaa tagtgaagtg
     3061 cgagggttga tgaaagtgat tgaagaatta cgggttgaga atacgccact aagtaccagc
     3121 atagccgacc atatcgaaag ttttacagac tatgactttg cccatctgct ttttagtgat
     3181 ggttatgtag agcagtctat cagccttgaa aaacaactga acattataca ggttgccgac
     3241 ttggtacttc ctgacaagga aacttccttt gaggaatata ccacaatgga gttactatcg
     3301 gtagcaatgc tgattgtcat tagtaccttt gcgttggact ttatccatac agaccgaagt
     3361 attttcaaga ttgtagactt agacgaagca tggagcttct tacaggtggc acaagggaaa
     3421 acactatcta tgaagctggt tcgtgctggt cgtgctatga acgctggggt atatttcgtg
     3481 acccaaaata cagatgacct cttagatgaa aaactgaaaa ataacctcgg cttaaaattt
     3541 gcctttcgtt ccactgacct taacgagatt aaaaaaaccc ttgccttttt tggtgtagac
     3601 ccagaggacg aaaacaatca gaagcgattg cgtgatttgg aaaacgggca atgccttatc
     3661 agtgatttat atggtcgtgt cggtgtgata cagttccacc ctgtatttga agaactgctc
     3721 catgcctttg ataccagacc acctgtgcga aaagaggtgt aaatgtgaaa ccatcaatat
     3781 taaacagaat aaaatcaaac tggacgctga aacgtctagg taaagtggca atgacagtgg
     3841 ctttcacact tgtgattgcc atttttcttt tagccatgct gggaacggtg gttcaagctg
     3901 cgggcttggt agatgatacg gtcaatgtgg caaatgaata cagccgatac ccacttgaaa
     3961 actatcaact ggatttttat gtggataata gctggggctg gctaccgtgg aactggtcgg
     4021 acggaattgg aaaacaagtc atgtatggac tatatgccat taccaatttt atttggacaa
     4081 tcagtcttta tgtttccaat gcgacgggtt acttagtaca ggaagcctat tccttagact
     4141 tcatttccgc tacagcagat tccattggca agaatatgca gacccttgca ggggttacgc
     4201 ctagtggact atcaacagag ggtttctatg ttggattcct tttactcttg attttggttc
     4261 ttggggttta tgttgcctat acaggactga taaagagaga aaccacaaag gcaattcatg
     4321 ccctcatgaa ttttgtgctg gtttttatcc tatcggcttc ctttattgcc tacgctcccg
     4381 actacattaa aaaaatcaat gacttttcat cagacatcag caacgctagt ttgtcactgg
     4441 gtacaaaaat tgtcatgccc cattcagata gtcaaggcaa ggacagtgtg gacttgatac
     4501 gtgacagcct attttccata caggttcagc aaccgtggct actgcttcaa tataacagtt
     4561 cagacattga aagtattggt attgaccgtg tggaaagcct gctctcaacc agtccagatt
     4621 ccaacaatgg ggaagacaga gaaaaaattg ttgcggaaga aattgaagat agaagcaata
     4681 ccaatatgac gattacaaag acgattaacc gtttaggtac agtcttcttc ctatttgtct
     4741 tcaatattgg gatttccata tttgtattcc tattaacagg aatcatgatt ttctcgcagg
     4801 tactttttat catctatgct atgtttctgc ctgtgagctt tattttaagc atgattccat
     4861 catttgatgg tatgtcaaaa cgagccataa caaagctctt taataccatt ttgacacgag
     4921 ctggaatcac attgattatt acgacagcat ttagtatttc aaccatgctc tataccttat
     4981 cggctggtta tccgttcttt ttgattgctt ttctacagat tgtgaccttt gcaggaatct
     5041 actttaagct gggcgattta atgagtatgt tttctctaca gagtaacgat tctcaaagtg
     5101 tgggaagtcg tatgatgaga aaacctcgta tgcttatgca cgctcacatg caccgtctac
     5161 agcggaaact tggacgctcc gtgactgctt taggggctgg gtctgccatt gccagtgcta
     5221 cgggtaaaaa aggacagtcg ggttcgggaa gttctgcgag tacacaagca gatcactctc
     5281 gaccaaacgg gcaggaaaaa tcaacactag gaaagcgtat cggtcaaacc atcggtacag
     5341 tagctgatac caaagacaga atggtagata ctgctggtaa tttgaaagaa caggttaagg
     5401 atttgccgac caatgcaaga tatgcagtat atcaaggaaa atctaaagtg acggataatg
     5461 tccatgattt aaccagaagt atttctcaaa ccaaagcgga taaagccagt ggacgcaaga
     5521 aacagcagga acaaagacgg aaaaccattg cggagcgtcg ctctgaaatg gaacaggtca
     5581 aacagaaaaa acagccagct tcttccgttc atgaaagacc agccactaag caagaacaat
     5641 ctcatgatgg acagacttca aggcaaacaa ctgtacaggc ttcctatagg gaatctcaac
     5701 aagccaaaca agagcgtcca acagttaagt ccgattcttc aagtttaaaa acggaacgtc
     5761 aaagtaatac agttcaagaa agaacggttc aaaagccagt aacttcaact gcaccaacag
     5821 atagagcttc acaacgttca atcacaaaag aacgtcagtc tactgttcaa agagtaccac
     5881 tacaaaatac aaaaagtaga ccaccaatca aaaccgccac cattaagaaa ggcagtaaga
     5941 aaccatgaag ctgaaaactt tagtgattgg tggttcggga ttattcttga tggtcttctc
     6001 actgcttctg tttgtcgcca ttttattttc agatgaacaa gatggcggtt tttccaacat
     6061 tcactatggc ggtgtggatg tttccgcaga agtgctggct cataagccta tggtagaaaa
     6121 agttgccaaa gaatatggaa ttgaagaata cgtcaatata cttcttgcga ttatacaggt
     6181 ggaatcgggt ggtacagcag aagatgttat gcagtcctcg gaatccctcg gtcttccacc
     6241 taattcattg agtacagaag aatccattaa gcaaggtgtg aagtatttca gtgagttatt
     6301 agccagtagc gaaaggcttg gtgtagattt agaatcggtt atccagtcct acaattatgg
     6361 tggtggtttc ttaggatatg tggctaatcg tgggaataaa tatacctttg aactggctca
     6421 aagtttctca aaagagtatt cgggtgacga aaaagtgtct taccccaatc ccatagccat
     6481 acctatcaat gggggctggc gatacaatta cgggaatatg ttttatgtgc aactggtaac
     6541 gcagtatctt gtcacaacag agtttgatga tgatacagta caagccatca tggacgaagc
     6601 tctgaaattt gaaggctgga agtatgtcta tggcggagct tccccgacta cctcttttga
     6661 ttgtagcgga ctgacacaat ggacgtatgg aaaagctgga atcaacttac cacgaacagc
     6721 acaacagcaa tatgatgtaa cccggcatat cccattattg gaagcaaaag ccggcgattt
     6781 ggttttcttt cattctacct ataacgctgg ctcttatatt actcatatcg ggatttattt
     6841 aggcgataac cgtatgtttc atgcaggcga ccctatcggt tatgccgact taacaagctc
     6901 ttactggcaa cagcatttag tgggagcagg acgaatcaaa caataagaaa ggacgattca
     6961 atgatgaaat tcggaaaaaa tcagaataca gaaaaacaga caccaaagga aaagaaacct
     7021 cgtgtctata aggtcaatcc tcgtaaaaag gttgtgattg tcctatgggt acttttagga
     7081 cttagtttca gctttgcgat attcaagcac tttacagcca ttgataccca taccattcat
     7141 gaaaccacca tcatagaaaa ggaatatgtc gatactcatc atgtggaaaa ttttgtagag
     7201 aactttgcga aagtctacta ttcatgggaa ctaaacgaca agtccattga taatcgcata
     7261 gaaaacctga aagcatatct gacagaggaa cttcaagctc tgaatgtcga tacagttcgt
     7321 aaagatattc ctgtatcgtc ttctgtaaaa ggatttcaga tatggacggt agaagcagat
     7381 ggcgacaatc aatttgatgt aacctacagt gtagaccaac tcattacaga gggggaaaat
     7441 acaaagaccg tccactctgc ttatatagtg agtgtctatg tagacagtac tggaaatatg
     7501 gtcctcatta agaatccgac cattactagc ataccaaaga aatcagacta taaaccaaaa
     7561 gctattgaaa gtgagggtac ggttgattcc attacaacca atgaaatcaa tgagttttta
     7621 acgacgttct tcaagctcta tcctacagcg acagccagtg aactttccta ctatgtgaat
     7681 gacgggatat taaaaccaat cggaaaagag tacatctttc aagaactggt aaatcctatt
     7741 tacaatcgta aggataatca agtcacggta tcgctgacag tggagtatat cgaccagcag
     7801 accaaagcaa cgcaggtatc tcaatttgat ttggtacttg aaaagaacgg gagtaattgg
     7861 aagattatag aataacaaat attggtacat tattacagct attttgtaat cacgtactct
     7921 ctttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat tatttaagta
     7981 tctatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac tgtcaatttg
     8041 atagtgggaa caaataattg gatgtccttt tttaggaggg cttagttttt tgcacccagt
     8101 ttaagaatac ctttatcatg tgattctaaa gtatccggag aatatctgta tgctttgtat
     8161 gcctatggtt atgcataaaa atcccagtga taagagtatt tatcactggg atttttatgc
     8221 ccttttgggc ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
     8281 tcatgttgat gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat
     8341 tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg
     8401 tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt
     8461 gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc
     8521 agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg
     8581 tatattattt catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat
     8641 tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc
     8701 cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac
     8761 cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat
     8821 gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa
     8881 ttgctccttg taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct
     8941 tatagaagtg ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg
     9001 cggaaatgtc ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct
     9061 ttatggcgga atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa
     9121 aattacagaa atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc
     9181 cggggaaatt gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac
     9241 aaagctattg ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt
     9301 tgaaccgagc aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga
     9361 cagtgacccg cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt
     9421 cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga
     9481 gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata
     9541 taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc
     9601 accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa
     9661 tcaatcattt caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata
     9721 tggttggaat gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt
     9781 tagtacccca gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa
     9841 agctggaaca gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata
     9901 tctttcacga gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt
     9961 gaaaaataat gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg
    10021 tagtgattta actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta
    10081 ccatgttact accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa
    10141 agtacgatat atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt
    10201 ttcttgttaa ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg
    10261 aattaattat gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc
    10321 tttgcgtttt atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg
    10381 atattgcaaa tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta
    10441 tgttaacctt ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca
    10501 aaaggttact cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg
    10561 gccattcttt cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg
    10621 catttccagc actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta
    10681 aagcatttgg tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg
    10741 gtggaatgat agcccattat attcattggt cctatcttct actcattcct atgataacaa
    10801 ttatcactgt tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt
    10861 ttgatatcaa aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa
    10921 catcatatag catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac
    10981 atatcaggaa agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta
    11041 tgattggagt tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg
    11101 ttccttatat gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta
    11161 ttttccctgg aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata
    11221 gaagaggtcc tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa
    11281 ctgcttcctt tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt
    11341 taggtgggct ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac
    11401 agcaggaagc tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa
    11461 caggtattgc aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac
    11521 ctatggaagt tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa
    11581 tcattgtcat tagttggctg gttaccttga atgtatataa acattctcaa agggatttct
    11641 aaatcgttaa gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg
    11701 aattcaaatc tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc
    11761 tctcttgtat cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca
    11821 ataaaaattt tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata
    11881 aaaattggca agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc
    11941 tgtcccttgc tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag
    12001 agggcaggtt tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat
    12061 ggttttggtc ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata
    12121 gtgtgttata ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg
    12181 ccacctaaaa aggagcgatt
//
LOCUS       DACGLI010000204         9694 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.085, whole genome shotgun sequence.
ACCESSION   DACGLI010000204 DACGLI010000000
VERSION     DACGLI010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.085"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            215..1126
                     /locus_tag="IXT22_003113"
     CDS             215..1126
                     /locus_tag="IXT22_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAQ4864390.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1279..1764
                     /gene="vanZ"
                     /locus_tag="IXT22_003114"
     CDS             1279..1764
                     /gene="vanZ"
                     /locus_tag="IXT22_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAQ4864391.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2051..2380)
                     /locus_tag="IXT22_003115"
     CDS             complement(2051..2380)
                     /locus_tag="IXT22_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864392.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            2685..3014
                     /locus_tag="IXT22_003116"
     CDS             2685..3014
                     /locus_tag="IXT22_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4864393.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            3004..3291
                     /locus_tag="IXT22_003117"
     CDS             3004..3291
                     /locus_tag="IXT22_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4864394.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(3570..4133)
                     /locus_tag="IXT22_003118"
     CDS             complement(3570..4133)
                     /locus_tag="IXT22_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864395.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(4326..4898)
                     /locus_tag="IXT22_003119"
     CDS             complement(4326..4898)
                     /locus_tag="IXT22_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HAQ4864396.1"
                     /translation="MNKAIFWDLLGTLGGDSRTLINQNFNFFKDTIPALKKAAQSHYL
                     NIIITNQSHISHGRITMAEYTDALESLINELEKNDIQITDVYTCPHARKDNCDCKKPQ
                     PTFVNEALKKYDLNPSKCFVVGDSGKNDMMLAKNAGINSVLLLTGEGIDSLTKYRHLW
                     SETKPTFIAENSLDAINKIHMYADGDSSDS"
     gene            5686..6261
                     /locus_tag="IXT22_003120"
     CDS             5686..6261
                     /locus_tag="IXT22_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4864397.1"
                     /translation="MKNKFKYLFTILALLPITTSTLITPTIAKASEKQEDSVSYEIVK
                     NDLYIQFEEELAELIASNQSTVSVPDLFSTQSVLSTSSQDNSISEEQFFSLVEKYDGA
                     ELTAVVNSQDAFTTKFVNGGVNSYATSYRGLNALRSELKYNAGALKVGGTLVGTAGGL
                     LGVLLGMVTGDYLSGHCDDAAAGVSAFIQAG"
     gene            complement(6444..7196)
                     /locus_tag="IXT22_003121"
     CDS             complement(6444..7196)
                     /locus_tag="IXT22_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4864398.1"
                     /translation="MMLNEQTEVKLAELKLSGMLESYREQMTNKEYQSMSFEDRFNLM
                     VDLEHSRRKNNKLQRLIKSANFRNASASIEDIEYHPDRNLDKNLILKLASGTYLEEHH
                     NIILMGASGNGKTYIANAFGIQACRQYYNVKYIRLPELLDELTISKNQADGSFRKIIN
                     RYKKVQLLIIDEWLLTNLSLENSTFLLEIIESRLKTASTIFCSQFHPEGWHEKLGNPQ
                     IADAILDRIIHDSYQILVDGKVSMRERYGIRN"
     gene            complement(7196..8737)
                     /locus_tag="IXT22_003122"
     CDS             complement(7196..8737)
                     /locus_tag="IXT22_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010632830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAQ4864399.1"
                     /translation="MFRYRRILEMHSEGISIRSIAASTGNSRQKITEVIRKAEEKGIA
                     RALSEEMTDQWLGEFLFPEKQLEANGRHLPDFDKIHKELAKPNVTLTLLHQEYAVECR
                     MSGKIPYAYRTFCDYYNAFARKHKATMRIRRKPGEIMEVDWAGSPAYVIDRDTGEKVK
                     AYVFVATLPCSQLSYAEAFLTMKSVAWITAHNHAFEYFGGSTDIIVPDNLKTGVKKNE
                     GIDVILNESYRELGEHYGSIILPARVSTPKDKPSVEGSVGVISTWIIAALRNTHCFTI
                     EDLNREIRMKLNEFNERPFTKKPGSRIRAFEEEEKFALNPLPLAPYKMSVWKKAKVQL
                     NYHVSVESMFYSVPYEYIQQNIDIRMTENLIELYFNSMRIATHKRLYGKFGQYSTVRD
                     HMPDNHKMYVDHTPESSMEWAETIGSSTVKVVQHLLDRYQNEKQALKSIMSLKSFGKK
                     YSKNEIETACSTALNLASLPSVKIIQTILKGNKQKRATSQSHIEDTNIEKHGFTRGAS
                     YFGGK"
BASE COUNT         3116 a         1599 c         1723 g         3256 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccgta tcacttatga aaattcatct
       61 acattggtga taatagtaaa tccagtaggg cgaaataatt gactgtaatt tacggggcaa
      121 aacggcacaa tctcaaacga gattgtgccg tttaagggga agattctaga aatatttcat
      181 acttccaact atatagttaa ggaggagact gaaaatgaag aagttgtttt ttttattgtt
      241 attgttattc ttaatatact taggttatga ctacgttaat gaagcactgt tttctcagga
      301 aaaagtcgaa tttcaaaatt atgatcaaaa tcccaaagaa catttagaaa atagtgggac
      361 ttctgaaaat acccaagaga aaacaattac agaagaacag gtttatcaag gaaatctgct
      421 attaatcaat agtaaatatc ctgttcgcca agaaagtgtg aagtcagata tcgtgaattt
      481 atctaaacat gacgaattaa taaatggata cgggttgctt gatagtaata tttatatgtc
      541 aaaagaaata gcacaaaaat tttcagagat ggtcaatgat gctgtaaagg gtggcgttag
      601 tcattttatt attaatagtg gctatcgaga ctttgatgag caaagtgtgc tttaccaaga
      661 aatgggggct gagtatgcct taccagcagg ttatagtgag cataattcag gtttatcact
      721 agatgtagga tcaagcttga cgaaaatgga acgagcccct gaaggaaagt ggatagaaga
      781 aaatgcttgg aaatacgggt tcattttacg ttatccagag gacaaaacag agttaacagg
      841 aattcaatat gaaccatggc atattcgcta tgttggttta ccacatagtg cgattatgaa
      901 agaaaagaat ttcgttctcg aggaatatat ggattaccta aaagaagaaa aaaccatttc
      961 tgttagtgta aatggggaaa aatatgagat cttttattat cctgttacta aaaataccac
     1021 cattcatgtg ccgactaatc ttcgttatga gatatcagga aacaatatag acggtgtaat
     1081 tgtgacagtg tttcccggat caacacatac taattcaagg aggtaaggat ggcggaatga
     1141 aaccaacgaa attaatgaac agcattattg tactagcact tttggggtaa cgttagcttt
     1201 ttaatttaaa acccacgtta actaggacat tgctatacta atgatacaac ttaaacaaaa
     1261 gaattagagg aaattatatt gggaaaaata ttatctagag gattgctagc tttatattta
     1321 gtgacactaa tctggttagt gttattcaaa ttacaataca atattttatc agtatttaat
     1381 tatcatcaaa gaagtcttaa cttgactcca tttactgcta ctgggaattt cagagagatg
     1441 atagataatg ttataatctt tattccattt ggcttgcttt tgaatgtcaa ttttaaagaa
     1501 atcggatttt tacctaagtt tgcttttgta ctggttttaa gtcttacttt tgaaataatt
     1561 caatttatct tcgctattgg agcgacagac ataacagatg taattacaaa tactgttgga
     1621 ggctttcttg gactgaaatt atatggttta agcaataagc atatgaatca aaaaaaatta
     1681 gacagagtta ttatttttgt aggtatactt ttgctcgtat tattgctcgt ttaccgtacc
     1741 catttaagaa taaattacgt gtaagatgtc taaatcaagc aatctgatct ttcatacaca
     1801 taaagatatt gaatgaattg gattagatgg aaaacgggat gtggggaaac tcgcccgtag
     1861 gtgtgaagtg aggggaaaac cggtgataaa gtaaaaagct tacctaacac tatagtaaca
     1921 aagaaagccc aattatcaat tttagtgctg aggaattggt ctctttaata aatttcctta
     1981 acgttgtaaa tccgcatttt cctgacggta cccccaaact aagatttcat agatagattt
     2041 tctgataact ttaaaaaaca cgaatagcgg aaaggatgtc ttcattcgct aaagagtaat
     2101 aaactacttt tccatcttga cgtgattttg ccattccatg tttttttaaa aaacgtaaat
     2161 ggtgtgacgt tgtagcgaca ctagcagtaa gtatttctgc taaatcacag acgcacattt
     2221 ccttataggt ttctaaagca tagaaaattt taattctaga aaaatcgctg aaacatttcc
     2281 ctaacacaag taagtttgaa aaatcttttt gatccaattt attttttatt ccatttactt
     2341 tttctttatg tacgacagtc acttggcaaa cttttttcat tcatctcacc tcacattcaa
     2401 acgattattt gaatgaagta tacctatttg atcactcttt tgtcaatcta ccttaattcc
     2461 aatacactat tataagcaat ttcatgtatt gaagtaaact tacttgcaag tgcgtttttg
     2521 attccaagtt aaaaacatat tattattcta cataatttcc taatcaaata aaactccttt
     2581 gaaaattgtt ctaaaggagt tttattattt tgtatttcta ctaaaaatag cgtacaatgt
     2641 aattactaag taattacgaa atgtaaaata atggaggaaa taatatgatt acaaaaacaa
     2701 gaaaacaagg aaattctatt atgttaacgg tccctaaaga attcgatgtg cccaatggtg
     2761 ttgaagtaga agctaagctt gtagagaatg gtatccttta tgagtttgta gagcctaaaa
     2821 aagaattttt tgattttagt gaagatattt tggctgatat tctttcagaa ggttatagca
     2881 aacaagagat cttaaaagaa tttagaaata gaaaaaatgc gttaacttct gcatttaaat
     2941 ctattgctga agatactgtt gcaaattcta aaccgatgac aaaagaggag ttggcagcag
     3001 aaattggctt atgagattct accttctaaa cacgtaataa agtatctaaa aaaattaaaa
     3061 gagaaaacat taaaagaaca atttttaacg ataatttatg atgagatagc agttcgtcct
     3121 cattcgggag aacaaaaaac gggtgattta tcaggaattt gggctattgg attcaagtat
     3181 gcaggtacga catatcgcgt tgcatatgaa attaaagata atgcagtgat acctatctta
     3241 ctatgtggaa cgcatgaaaa tttttatgaa caattaaaaa agattaggta agaacccaat
     3301 gtttcaactt gagaggatag acgacacttt aaaagataat ttttaacagc tgagagttgt
     3361 aataccctat aattttaaac cactaaccta tatatttatg aaaaatagaa aaaattaaaa
     3421 cgcattttaa gcctctttca aattaaaagc ttcatcctta tgcacaaaga gggcttaaaa
     3481 tgcgttattt tatattgttt tttagtaata ataaaaaaat cactctaatt ctcccataaa
     3541 tattatagat tcctaaagat taaaatagat tattccctat tgtcttttaa gtagcggtag
     3601 agtgttgcct tgctaatacc agtcatttcc gtaatttctt ttacgctata aacctgactt
     3661 ttatacaatt ttactgctcg atcaacatct ttctggttca ctcgtggacg gccaccttta
     3721 cgacctctcg cacgtgcact tttcaaacct tctttggtac gttcaacaat taaatcacgt
     3781 tcgaactgac taaatgcttg gaagacagtc atcattaagc gtccgtgagg cgtgctggta
     3841 tcgaagtttt ctttcaagct caccagctta acatggtgtt cttcaaaata ggtaacaagg
     3901 tcaatcaaat cctttgtact acgacccaat cgagaaaaac tttctacaat taccgtatct
     3961 cccggacgaa ttttatcttt taaacgattt agttggggac gaaccgcttt ggttcccgtc
     4021 attttctcag ttaggatttc attacaattt tgttcattga gtaagtctaa ttgacgattt
     4081 agttcttgtg aacgtgtact cactcgggca taaccataaa tgtatccact catgcttttc
     4141 ttcctttcgt actttaattc tggcttgatt gtatcataaa agggagttat agatacatag
     4201 ttaatgcaac aagttatgat acaaaatatg acctctttta tttaataaaa gaggtcattt
     4261 cattttgtct cataatcgat tgtttttgat acggttttta gtaataaatg gagactcttc
     4321 tggtatcatg aatcagaaga gtctccatct gcatacatat gtattttatt tatagcatct
     4381 aaactgtttt cagcaataaa agtaggtttt gtttcactcc acagatgtct atatttggtt
     4441 aaactatcaa ttccctctcc cgttaaaagt aaaacactgt ttataccagc atttttggcc
     4501 aacatcatat cgtttttacc ggaatcgcct actacgaaac acttacttgg atttaaatcg
     4561 tattttttta atgcttcatt gacaaatgta ggttgaggct tcttgcaatc acaattgtct
     4621 tttctagcat gagggcaagt gtatacatcc gttatttgaa tgtcattttt ctctaactca
     4681 tttattaagc tctctaaggc atcagtatat tctgccatag taatacgtcc atgtgaaata
     4741 tgactttgat tcgtaatgat gatatttaga taatgacttt gtgccgcttt ttttaaggcc
     4801 ggtattgtgt ctttaaaaaa attgaaattt tgattaatca gtgttctact atcccctccc
     4861 agcgtaccta acagatccca aaatatagct ttattcatgg atatttgtct ccctctcatt
     4921 ttaagaatag ttaactaaca agccaaggtg cttacagtat ttaaaagtag ttcttcgtaa
     4981 ttaaaacaaa aatattactt tttgaaaaag catattttat tttgccagtt taactatatc
     5041 atatttacag gagccactct ctattcactt tctatatgaa cttcttttga gggaatggat
     5101 atttcgaatc acataatcac tgatatagaa gagacttaga atttcagtta tattttgata
     5161 cagcaaagag tgtaaaaaag aagataccct cgttggcgaa aaacatttga atacaaacct
     5221 tacttttttg atgggatttc catgctagga gcacataaaa aactaaggtg ataataaatt
     5281 tatagtgatt tagtgtggag gttcttttgt taattgaaac cataaatagt aaaaaaatct
     5341 atttttaatg attgtacata ttaaagagaa aattgatata caccagctta tcaaagttga
     5401 gattaatact actactttga cctatgaaga tgattttata aataccttat agtaaagaaa
     5461 agttcaattt tttctgctat catctttttt tataaaagca acgattagtt tcccagatgt
     5521 aaatagaaaa gtgcttttga aacagctcga aaaacataat aatagattgt gagaggagga
     5581 aaaactattg caaaatcatt acgtaagaga tgttactctt gcttagattt tttatttttc
     5641 aagttgtggt attaaaagta gaaaaaatag aaagaaggat aaaaaatgaa aaataaattt
     5701 aagtatttat ttactatttt agccttattg ccaattacta catcgacctt aattactcct
     5761 acaatagcca aagcttctga aaaacaggaa gattctgtta gttatgaaat tgtaaaaaat
     5821 gatctttaca ttcagtttga agaagagtta gctgaattga ttgcttccaa tcaatcaact
     5881 gtttcagtcc ctgatttatt ttctacacaa tcagtattat ctacttctag tcaagataat
     5941 tctattagtg aagagcaatt tttttcttta gtcgaaaaat atgatggagc tgaattgaca
     6001 gctgttgtta attcacaaga tgctttcaca actaaatttg tgaatggtgg ggttaactca
     6061 tatgctactt cttacagagg attaaatgca ttgcgtagcg agttgaagta taatgctggt
     6121 gctttgaaag taggaggtac cttagttggc acagctgggg gattgttagg agtattatta
     6181 ggcatggtta caggggatta tttatctggc cattgcgatg atgcagcagc aggtgttagt
     6241 gcctttattc aagctggttg aatacggcat cgaaaatgta ccactagagc attgtttttt
     6301 accactaagt gcaaagaaat gtaccagtaa gtgcgacgcg gttaccattt caaataataa
     6361 aagcgacaat aatgaccaca aggtcaacta agagccactc atgaaaatca tggagtggct
     6421 cttaatttat tttaatgact catttaatta cggatgccgt aacgttcacg catagaaact
     6481 ttaccgtcta ccagaatttg ataagaatca tgtatgatcc tatctagaat ggcatcagcg
     6541 atttgggggt tgccgagctt ttcgtgccat ccttctggat ggaattgaga acagaaaata
     6601 gttgatgctg ttttaagacg ggattcgatt atttccaata gaaaggtgga attttctaac
     6661 gaaagattgg ttaatagcca ttcatcgatg atgagtaatt gaactttttt atatctgttg
     6721 attatttttc gaaaactacc atctgcttga tttttcgaga tggttaattc atctagtagt
     6781 tcagggagtc ggatgtattt cacgttgtag tattgccggc atgcctgtat tccgaaggca
     6841 ttggcgatat acgttttccc attccctgaa gcgcccatca aaatgatgtt atggtgttct
     6901 tccaaataag tcccactggc tagttttaaa atgaggttct tatctaaatt acggtccgga
     6961 tggtattcga tatcctcaat gctggcagag gcatttctaa agtttgcaga tttaatcaac
     7021 cgctgtagtt tattattttt tcgccgggaa tgctccagat caaccatgag gttgaagcgg
     7081 tcttcgaaac tcatggattg gtactcttta tttgtcatct gttcacgata ggattcaagc
     7141 atgcctgaaa gtttcaattc agctaatttt acttctgttt gctcatttaa catcattatt
     7201 tccctccaaa ataggacgca ccgcgagtga atccatgctt ttcaatgtta gtgtcttcaa
     7261 tatgtgattg gcttgttgct cgcttctgct tgttgccctt tagaatggtc tggataattt
     7321 taacagaagg caaagaagcc agatttaaag ctgttgaaca ggccgtttct atttcatttt
     7381 tagaatactt tttaccaaag ctcttcaaag acatgatcga ctttaaggct tgtttttcat
     7441 tttgataacg gtctaagagg tgttgaacaa cctttactgt tgaggaaccg atggtttcag
     7501 cccattccat cgaggattct ggggtatggt ccacatacat tttgtgatta tctggcatat
     7561 gatctctgac agtcgaatac tgcccaaatt tcccgtacag acgtttatgt gttgcgattc
     7621 gcatggaatt aaaatatagt tcaattagat tctctgtcat tcgaatatct atattttgtt
     7681 gaatgtattc gtatggaacg gaataaaaca tgctttcaac tgagacgtgg tagtttagtt
     7741 gaacctttgc ttttttccag acagacatct tataaggtgc cagtggaaga ggattaagtg
     7801 cgaatttttc ttcttcctcg aaggctctga tcctggatcc tggtttctta gtgaacggtc
     7861 gctcattgaa ttcatttaat ttcattctga tttcacgatt taaatcttcg attgtaaaac
     7921 aatgcgtatt gcgtaaggca gctataatcc aagtggagat gacgcctacg ctgccttcaa
     7981 cactgggctt atccttggga gtagaaactc gggcaggtaa aatgatggac ccgtaatgtt
     8041 cccctagctc tcgatatgat tcattaagga tgacatcgat gccttcattc ttttttacac
     8101 ctgtttttag attatcggga acaattatgt cggtagaacc gccaaaatat tcaaatgcat
     8161 ggttatgtgc cgtaatccaa gccaccgatt tcatcgttag gaatgcttcc gcataagaca
     8221 attggctgca cggtaaggtt gccacaaaga cataagcctt tactttttca cccgtatctc
     8281 gatcgatgac ataagctggc gatccagccc aatccacttc cataatttca ccaggcttcc
     8341 gacggatgcg catagtggct ttatgctttc gcgcgaacgc attgtaatag tcacaaaatg
     8401 tacgataggc gtaagggatt ttcccactca tgcgacactc aactgcgtat tcctgatgaa
     8461 gaagcgtcaa ggtcacgttt ggtttggcca attccttgtg aatcttgtcg aagtcaggca
     8521 ggtgccgtcc attggcttct aattgttttt ctggaaacaa aaattcgcct agccattgat
     8581 cggtcatttc ttccgacaac gccctcgcta tccctttctc ctcagctttt cggataacct
     8641 cagtaatttt ctgacgtgag ttccccgtgc ttgctgcaat actgcgaata ctaattcctt
     8701 cactgtgcat ttcaagtatc cttcgataac gaaacataat aaaaatacct cctgtaaaat
     8761 aaatgtcaca ccctaaggtg tgcacctaca ttatacaaga ggtatttgtg gtacactgct
     8821 ttgcacttac tggtacattt ctttgccgag cctggtaaaa attattgcag agatggtaca
     8881 ttttcgatgc cgtaatcact ggttacacta gaggaggatc tagggtaacc cttactgaag
     8941 gtttccctat tagccatatt gatagtattt atgaagctgt aattaattaa gcaagaaatg
     9001 tggagatgat aaaaagcagt tctctcttgg gtaaagagaa aactgctttt atctttttcg
     9061 ctaatgcttt ttggaattac ctcgctgtct aaaaagggaa gtcacagaaa aaagaattaa
     9121 cacactacct attattattg gtagtacagt taaaagagta atcttactaa gatcaaaatc
     9181 agaacttgct acactattaa taacaaaaaa caagccaacc aaaaaagtaa atacagatag
     9241 atatttatta gtcataaaag aatcttcctc tcgtattttt ttgttctagg aagctatgct
     9301 aatctaagtt cttcctaagt atagtgtctc atctaagtat agcttaatta agcatcttat
     9361 ggtttacatc aggtcacttt atagttgcaa ccgctcaaat ttgctttttg attttattat
     9421 ctacgttatt agtaaaaaat tagttgattt ggttttttta tttcgttgat attttatctg
     9481 tttagtaagt agagttggta acagtgaatg tttactaacc cagatacact tatatatgcg
     9541 tccatttgta gagagagccg tttcaatata agaatgttca caaaatgttc tcttactaat
     9601 taaacccgta tatattaaac tatgagtata ttaattttag gagggatttt ttgagagtca
     9661 agtccagact cctgtgtaaa atgctataca atgt
//
LOCUS       DACGLI010000205         8097 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.091, whole genome shotgun sequence.
ACCESSION   DACGLI010000205 DACGLI010000000
VERSION     DACGLI010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.091"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            144..1580
                     /locus_tag="IXT22_003123"
     CDS             144..1580
                     /locus_tag="IXT22_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4864400.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1769..4216
                     /locus_tag="IXT22_003124"
     CDS             1769..4216
                     /locus_tag="IXT22_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4864401.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4446..5513
                     /gene="rlmN"
                     /locus_tag="IXT22_003125"
     CDS             4446..5513
                     /gene="rlmN"
                     /locus_tag="IXT22_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4864402.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5706..6809)
                     /locus_tag="IXT22_003126"
     CDS             complement(5706..6809)
                     /locus_tag="IXT22_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4864403.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7362..7910
                     /gene="aac(6')"
                     /locus_tag="IXT22_003127"
     CDS             7362..7910
                     /gene="aac(6')"
                     /locus_tag="IXT22_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4864404.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2709 a         1380 c         1755 g         2253 t
ORIGIN      
        1 ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac aacctccttt
       61 acataatttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg aacgattgaa
      121 ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt ccaaaagatt
      181 ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa gaagatggga
      241 aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt aaaggaacga
      301 acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct ttaatgaaag
      361 aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt cctaatggac
      421 gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac gaattgattg
      481 aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa gcattgcaag
      541 atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat tatgcagaaa
      601 cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat gaacaaaata
      661 tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca gacccgaaac
      721 gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc aataaatttc
      781 acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca aattatccaa
      841 ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg atggccaatt
      901 attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg ttcttagaag
      961 aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa tctgctaaac
     1021 cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat ccattaaacg
     1081 gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa gaaactggag
     1141 ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat tgggactggg
     1201 agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt taccgcatgc
     1261 cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa gataaacaaa
     1321 tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc aaagaagcaa
     1381 tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat ttgcttagct
     1441 ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac gaaacacaag
     1501 aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa ctgattgaag
     1561 aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct ggatatggcc
     1621 gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata agctgaaaaa
     1681 tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt ttttgtataa
     1741 tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta ctaaaaaaag
     1801 gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc tgacgattgg
     1861 tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag gttttttagg
     1921 aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa tcctctgtct
     1981 tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt caattggtaa
     2041 aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat tgttacatgc
     2101 ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga catgggattt
     2161 gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg ggatgattgg
     2221 agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt atttagcagc
     2281 agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct atcagctgtt
     2341 aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg atcctgccaa
     2401 gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag aagcgaaaga
     2461 agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat atgagaagaa
     2521 aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac cagaaaatac
     2581 agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata tccatcctgc
     2641 gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag aaggtttttc
     2701 agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag cagaacagga
     2761 aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa ctgtggatca
     2821 aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa ctttccaaag
     2881 tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca caaaattcga
     2941 agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag atgatatcgc
     3001 gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta aatcactgat
     3061 tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa tcatcgaagc
     3121 acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg tttctggacg
     3181 ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt cgactggtag
     3241 tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg ctaagcccca
     3301 tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt acaacggcat
     3361 acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag ccttacaaaa
     3421 agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag taagaaatat
     3481 ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga aacatccaac
     3541 cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg tagccagcaa
     3601 tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg ggattcatat
     3661 gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca aagcaaatgt
     3721 accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga tcattgattc
     3781 taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa tgggtgagaa
     3841 taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac gggtcgttca
     3901 atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga cagatgaagt
     3961 tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag caaaagcact
     4021 tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc ggatcggtta
     4081 caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg gcccgtcaga
     4141 aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa cgttgccgga
     4201 cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac caataaaaag
     4261 acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct aatacggtat
     4321 gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat ttgtgaagta
     4381 ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa aagagggaaa
     4441 atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc aattggttta
     4501 tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg tatcaaaaac
     4561 gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa aaattatcgg
     4621 agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg gatggtacag
     4681 taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg atgagacaag
     4741 aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc tgtacgtttt
     4801 gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt gttgcacaga
     4861 tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg
     4921 ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac tttttgcata
     4981 tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt tccactagtg
     5041 gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat ctggctattt
     5101 ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc
     5161 caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac cgtcgaatca
     5221 cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg caacaattag
     5281 cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca tataatccag
     5341 tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga ttttatgatg
     5401 tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca gatattgatg
     5461 cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc
     5521 ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga actgttcaac
     5581 ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac aagaaaaacc
     5641 ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg ggttttagca
     5701 attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg ataagtttct
     5761 acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac atgtttaata
     5821 tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac attgagattc
     5881 atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat tttatcaaac
     5941 aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac agatgctccg
     6001 tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga gtgtgccata
     6061 gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac aatgatatcc
     6121 gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt caatgcttgc
     6181 gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc taatctatcc
     6241 gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt ggataaagca
     6301 tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc tgtatcaatg
     6361 aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta
     6421 tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg aaaggtgaag
     6481 actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg gccaccaccg
     6541 actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg ttcaatattt
     6601 ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa
     6661 gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat cagcactact
     6721 tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt tccaatggta
     6781 taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg ttgaaacggg
     6841 ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga ggtgaaccta
     6901 agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa taagtatcct
     6961 aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt tcctcttagt
     7021 atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa attaagatta
     7081 ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa gcaaaagata
     7141 atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt cctgatcttt
     7201 cctattttga ataaagtgtt tctgtataat ttttttattt tataagtaag ataaataatg
     7261 aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt tcgttttttc
     7321 aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc agtgaatttg
     7381 accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg acttggccgg
     7441 aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca gaacgaatcg
     7501 cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc cctcaatacg
     7561 gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga aagaaccaaa
     7621 taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga ggaatcacga
     7681 tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg gacctgtatg
     7741 agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg tatgaattct
     7801 atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc tgggacaaac
     7861 cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa taaaaagagg
     7921 ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat tacttcttga
     7981 atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc gtgtaccaga
     8041 ggttgtgaaa aagtcgctag tttcgagtag taagaaaaat tttgtgaaaa tggcttt
//
LOCUS       DACGLI010000206         5775 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.102, whole genome shotgun sequence.
ACCESSION   DACGLI010000206 DACGLI010000000
VERSION     DACGLI010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.102"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            complement(86..3010)
                     /locus_tag="IXT22_003128"
     CDS             complement(86..3010)
                     /locus_tag="IXT22_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAQ4864405.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            3156..3731
                     /locus_tag="IXT22_003129"
     CDS             3156..3731
                     /locus_tag="IXT22_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4864406.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            3945..4640
                     /gene="vanR"
                     /locus_tag="IXT22_003130"
     CDS             3945..4640
                     /gene="vanR"
                     /locus_tag="IXT22_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAQ4864407.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            4618..5769
                     /locus_tag="IXT22_003131"
     CDS             4618..5769
                     /locus_tag="IXT22_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4864408.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPGFCCKVLNKE"
BASE COUNT         1782 a         1090 c         1090 g         1813 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt ctaaaatact ttgttttttt
       61 acctgtctac ttgacagggg gcagttcact ctgagttaaa atggtattct cctagtaaat
      121 taatatgttc ccaacctaag ggcgacatat ggtgtaacaa atcttcatta aagctacctg
      181 tccgtttttt atattcaact gctgttgtta ggtggagagt attccaaata cttatagcat
      241 tgataattat gtttaaagca ctggctcttt gcaattgatg ctgtatggtg cgttctctaa
      301 gctcaccttg ttttccgaag aaaatagctc ttgccaatcc attcatggct tctcctttat
      361 tcaatcctct ttgtattttt cttcttaatg attcatccga tatataattc aaaataaaga
      421 tcgttttttc tattcggccc atctcacgta aggctgtagc taagctgttt tgtcttgaat
      481 aggaacctag cttccccata ataagggatg ctgaaactgt tccctccctt atagaatgag
      541 ctaatcgcaa aacatcctca taattttctt taatgacctt tgtatttatt tgtccacgta
      601 aaatggcttc tagttttgga tactcacttg ctttatctat cgtaaataat tttgagtccg
      661 ataaatccct tattcttggg gcaaatttaa atcctaataa atgagtcagt ccgaatattt
      721 ggtcagtgta accggcagtg tctgtataat gttcctctat gtttagatcc gtctcatgat
      781 gtaacaaacc atccaaaaca tgaatcgcat ctcttgaatt agtatgaata atctttgtgt
      841 agtaagaaga gaattgatca cttgtaaatc ggtagatggt ggctcctttt ccagttccat
      901 aatgtggatt tgcatctgca tgtagtgatg aaacacctag ctgcattctc ataccatctg
      961 acgaagatgt tgtaccgtcg ccccaataga aaggcaattg taatttatga tgaaagttta
     1021 ctaatatggc ttgggcttta ttcatggcat cttcatacat gcgccattga gatacattgg
     1081 ctagttgctt atatgtaagt ccgggtgtgg cttcggccat cttgctcaag ccaatattca
     1141 ttcccattcc taaaagggca gccatgataa tgattgtttc ttccttatct ggttttcgat
     1201 tattggaagc atgagtgaat tgctcatgaa atcctgttat atgggccaca tccatgagta
     1261 aatcagttaa ttttattctt ggtagcatct gataaaggct tgcactaaat ttttttgctt
     1321 cttctggaac atctttttct aagcgtgcaa gtgatagctt tcctttttca agagaaaccc
     1381 catctaactt attggaattg gcagctaacc actttaacct ttcattaaag ctgctggttc
     1441 tctccgttat ataatcttcg aatgataaac taactgataa tctcgtattc cccttcgatt
     1501 gattccatgt atcttccgaa aacaaatatt cctcaaaatc cctatattgt ctgctgccaa
     1561 caatggaaac atctcctgcc cgaacatgct cccgaagttc tgttaaaaca gccatttcat
     1621 agtaatgacg attaattgtt gtaccatcat cctcgtataa atgtcttttc catcgttttg
     1681 aaataaaatc cacaggtgag tcatcaggca cttttcgctt tccagattcg ttcattcctc
     1741 ggataatctc aacagcttgt aaaagtggct catttgcctt tgtagaatga aattccaata
     1801 ctcttaatag cgttggcgta tattttctta gtgaataaaa ccgtttttgc agtaagtcta
     1861 aataatcata gtcggcagga cgtgcaagtt cctgagcctc ttctactgaa gagacaaagg
     1921 tattccattc aataaccgat tctaaaacct taaaaacgtc taatttttcc tctcttgctt
     1981 taattaatgc ttgtccgatg ttcgtaaagt gtataacttt ctcatttagc tttttaccgt
     2041 tttgtttctg gatttcctct tgagccttac gaccttttga taacaaacta agtatttgcc
     2101 tatcatgaat ttcaaacgct ttatccgtta gctcctgagt aagttgtaat aaatagatgg
     2161 ttaatatcga ataacgttta ttttcttgaa agtcacggaa tgcatacggc tcgtatcttg
     2221 agcctaagcg agacagctgc aacaggcggt tacggtgcaa atgactaatt tgcactgttt
     2281 ctaaatccat tcctcgtatg tattcgagtc gttctattat ttttagaaaa gtttcgggtg
     2341 aaggatgacc cggtggctct tttaaccaac ccaatatcgt tttattggat tcggatggat
     2401 gctgcgaggt aataatccct tcaagctttt ctttttgctc atttgttaga gatttactaa
     2461 ccgtattaaa tagcttcttt tcagccattg cccttgcttc ccacaccatt ctttcaagtg
     2521 tagtgatagc aggcagtata attttgtttt ttcttagaaa atctatgcat tcatgcagta
     2581 gatgaatggc atcaccattt tccaaagcta attgatgaag gtacttaaat gtcattcgat
     2641 attcactcag ggtaaaagtt acaaagtcgt attcacttcg aatttctttc aaatgatccc
     2701 aaagtgtatt ttccctttga ggataatgat caagcgagga tggactaaca ccaatctgtt
     2761 tcgatatata ttgtatgacc gaatctggga tgcttttgat atgagtgtat ggccaaccgg
     2821 gataccgaag aacagctaat tgaacagcaa atcctaaacg gttttcttcc ctccttcgct
     2881 tattaactat ttctaaatcc cgtttggaaa aagtgaagta ggtccccagt atccattcat
     2941 cttcagggat ttgcataaaa gcctgtctct gttccggtgt aagcaattct ctacctctcg
     3001 caattttcat tcagtatcat tccatttctg tattttcaat ttattagttc aattatatat
     3061 caatagagtg tactctattg atacaaatgt agtagactga taaaatcata gttaagagcg
     3121 tctcataaga cttgtctcaa aaatgaggtg atattttgcg gaaaatcggt tatattcgtg
     3181 tcagttcgac taaccagaat ccttcaagac aatttcagca gttgaacgag atcggaatgg
     3241 atattatata tgaagagaaa gtttcaggag caacaaagga tcgcgagcaa cttcaaaaag
     3301 tgttagacga tttacaggaa gatgacatca tttatgttac agacttaact cgaatcactc
     3361 gtagtacaca agatctattt gaattaatcg ataacatacg agataaaaag gcaagtttaa
     3421 aatcactaaa agatacatgg cttgatttat cagaagataa tccatacagc caattcttaa
     3481 ttactgtaat ggctggtgtt aaccaattag agcgagatct tattcggatg agacaacgtg
     3541 aagggattga attggctaag aaagaaggaa agtttaaagg tcgattaaag aagtatcata
     3601 aaaatcacgc aggaatgaat tatgcggtaa agctatataa agaaggaaat atgactgtaa
     3661 atcaaatttg tgaaattact aatgtatcta gggcttcatt atacaggaaa ttatcagaag
     3721 tgaataatta gccattctgt attccgctaa tgggcaatat ttttaaagaa gaaaaggaaa
     3781 ctataaaata ttaacagcct cctagcgatg ccgaaaagcc ctttgataaa aaaagaatca
     3841 tcatcttaag aaattcttag tcatttatta tgtaaatgct tataaattcg gccctataat
     3901 ctgataaatt attaagggca aacttatgtg aaagggtgat aactatgagc gataaaatac
     3961 ttattgtgga tgatgaacat gaaattgccg atttggttga attatactta aaaaacgaga
     4021 attatacggt tttcaaatac tataccgcca aagaagcatt ggaatgtata gacaagtctg
     4081 agattgacct tgccatattg gacatcatgc ttcccggcac aagcggcctt actatctgtc
     4141 aaaaaataag ggacaagcac acctatccga ttatcatgct gaccgggaaa gatacagagg
     4201 tagataaaat tacagggtta acaatcggcg cggatgatta tataacgaag ccctttcgcc
     4261 cactggagtt aattgctcgg gtaaaggccc agttgcgccg atacaaaaaa ttcagtggag
     4321 taaaggagca gaacgaaaat gttatcgtcc actccggcct tgtcattaat gttaacaccc
     4381 atgagtgtta tctgaacgag aagcagttat cccttactcc caccgagttt tcaatactgc
     4441 gaatcctctg tgaaaacaag gggaatgtgg ttagctccga gctgctattt catgagatat
     4501 ggggcgacga atatttcagc aagagcaaca acaccatcac cgtgcatatc cggcatttgc
     4561 gcgaaaaaat gaacgacacc attgataatc cgaaatatat aaaaacggta tggggggttg
     4621 gttataaaat tgaaaaataa aaaaaacgac tattccaaac tagaacgaaa actttacatg
     4681 tatatcgttg caattgttgt ggtagcaatt gtattcgtgt tgtatattcg ttcaatgatc
     4741 cgagggaaac ttggggattg gatcttaagt attttggaaa acaaatatga cttaaatcac
     4801 ctggacgcga tgaaattata tcaatattcc atacggaaca atatagatat ctttatttat
     4861 gtggcgattg tcattagtat tcttattcta tgtcgcgtca tgctttcaaa attcgcaaaa
     4921 tactttgacg agataaatac cggcattgat gtacttattc agaacgaaga taaacaaatt
     4981 gagctttctg cggaaatgga tgttatggaa caaaagctca acacattaaa acggactctg
     5041 gaaaagcgag agcaggatgc aaagctggcc gaacaaagaa aaaatgacgt tgttatgtac
     5101 ttggcgcacg atattaaaac gccccttaca tccattatcg gttatttgag cctgcttgac
     5161 gaggctccag acatgccggt agatcaaaag gcaaagtatg tgcatatcac gttggacaaa
     5221 gcgtatcgac tcgaacagct aatcgacgag ttttttgaga ttacacggta taacctacaa
     5281 acgataacgc taacaaaaac gcacatagac ctatactata tgctggtgca gatgaccgat
     5341 gaattttatc ctcagctttc cgcacatgga aaacaggcgg ttattcacgc ccccgaggat
     5401 ctgaccgtgt ccggcgaccc tgataaactc gcgagagtct ttaacaacat tttgaaaaac
     5461 gccgctgcat acagtgagga taacagcatc attgacatta ccgcgggcct ctccggggat
     5521 gtggtgtcaa tcgaattcaa gaacactgga agcatcccaa aagataagct agctgccata
     5581 tttgaaaagt tctataggct ggacaatgct cgttcttccg atacgggtgg cgcgggactt
     5641 ggattggcga ttgcaaaaga aattattgtt cagcatggag ggcagattta cgcggaaagc
     5701 aatgataact atacgacgtt tagggtagag cttccagggt tctgttgcaa agttttaaat
     5761 aaagaataaa atccc
//
LOCUS       DACGLI010000207         2993 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.136, whole genome shotgun sequence.
ACCESSION   DACGLI010000207 DACGLI010000000
VERSION     DACGLI010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.136"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            3..188
                     /locus_tag="IXT22_003132"
     CDS             3..188
                     /locus_tag="IXT22_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005611413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4864409.1"
                     /translation="MNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKF
                     VQAFILPDGDEIKISNE"
     gene            203..1072
                     /locus_tag="IXT22_003133"
     CDS             203..1072
                     /locus_tag="IXT22_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAQ4864410.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            1053..1787
                     /locus_tag="IXT22_003134"
     CDS             1053..1787
                     /locus_tag="IXT22_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4864411.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            1820..2728
                     /locus_tag="IXT22_003135"
     CDS             1820..2728
                     /locus_tag="IXT22_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAQ4864412.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            2725..2973
                     /locus_tag="IXT22_003136"
     CDS             2725..2973
                     /locus_tag="IXT22_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HAQ4864413.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
BASE COUNT         1047 a          420 c          662 g          864 t
ORIGIN      
        1 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttta
       61 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
      121 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agatgaaata aaaatatcta
      181 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
      241 atcatctttg ccttttatag aaggcattgt attagggggc tcacgtgcaa gaagcaccca
      301 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
      361 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
      421 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
      481 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
      541 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
      601 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
      661 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
      721 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
      781 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
      841 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
      901 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
      961 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     1021 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     1081 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     1141 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     1201 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     1261 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     1321 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     1381 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     1441 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     1501 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     1561 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     1621 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     1681 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     1741 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     1801 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     1861 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     1921 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     1981 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     2041 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     2101 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     2161 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     2221 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     2281 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     2341 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     2401 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     2461 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     2521 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     2581 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     2641 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     2701 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     2761 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     2821 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     2881 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     2941 ataatatatc ttttaacccg tggtgctagt taattttaat atcctaaaga ata
//
LOCUS       DACGLI010000208         2950 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.138, whole genome shotgun sequence.
ACCESSION   DACGLI010000208 DACGLI010000000
VERSION     DACGLI010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.138"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            297..1265
                     /locus_tag="IXT22_003137"
     CDS             297..1265
                     /locus_tag="IXT22_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAQ4864414.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1258..2289
                     /gene="vanA"
                     /locus_tag="IXT22_003138"
     CDS             1258..2289
                     /gene="vanA"
                     /locus_tag="IXT22_003138"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAQ4864415.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2295..2903
                     /locus_tag="IXT22_003139"
     CDS             2295..2903
                     /locus_tag="IXT22_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAQ4864416.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          876 a          563 c          714 g          797 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccg cttccagcga tgccagactt
       61 ggttgataaa aggaggtcct aagagatgta tataattttt taggaaaatc tcaaggttat
      121 ctttactttt tcttaggaaa ttaacaattt aatattaaga aacggctcgt tcttacacgg
      181 tagacttaat accgtaagaa cgagccgttt tcgttcttca gagaaagatt tgacaagatt
      241 accattggca tccccgtttt atttggtgcc tttcacagaa agggttggtc ttaattatga
      301 ataacatcgg cattactgtt tatggatgtg agcaggatga ggcagatgca ttccatgctc
      361 tttcgcctcg ctttggcgtt atggcaacga taattaacgc caacgtgtcg gaatccaacg
      421 ccaaatccgc gcctttcaat caatgtatca gtgtgggaca taaatcagag atttccgcct
      481 ctattcttct tgcgctgaag agagccggtg tgaaatatat ttctacccga agcatcggct
      541 gcaatcatat agatacaact gctgctaaga gaatgggcat cactgtcgac aatgtggcgt
      601 actcgccgga tagcgttgcc gattatacta tgatgctaat tcttatggca gtacgcaacg
      661 taaaatcgat tgtgcgctct gtggaaaaac atgatttcag gttggacagc gaccgtggca
      721 aggtactcag cgacatgaca gttggtgtgg tgggaacggg ccagataggc aaagcggtta
      781 ttgagcggct gcgaggattt ggatgtaaag tgttggctta tagtcgcagc cgaagtatag
      841 aggtaaacta tgtaccgttt gatgagttgc tgcaaaatag cgatatcgtt acgcttcatg
      901 tgccgctcaa tacggatacg cactatatta tcagccacga acaaatacag agaatgaagc
      961 aaggagcatt tcttatcaat actgggcgcg gtccacttgt agatacctat gagttggtta
     1021 aagcattaga aaacgggaaa ctgggcggtg ccgcattgga tgtattggaa ggagaggaag
     1081 agtttttcta ctctgattgc acccaaaaac caattgataa tcaattttta cttaaacttc
     1141 aaagaatgcc taacgtgata atcacaccgc atacggccta ttataccgag caagcgttgc
     1201 gtgataccgt tgaaaaaacc attaaaaact gtttggattt tgaaaggaga caggagcatg
     1261 aatagaataa aagttgcaat actgtttggg ggttgctcag aggagcatga cgtatcggta
     1321 aaatctgcaa tagagatagc cgctaacatt aataaagaaa aatacgagcc gttatacatt
     1381 ggaattacga aatctggtgt atggaaaatg tgcgaaaaac cttgcgcgga atgggaaaac
     1441 gacaattgct attcagctgt actctcgccg gataaaaaaa tgcacggatt acttgttaaa
     1501 aagaaccatg aatatgaaat caaccatgtt gatgtagcat tttcagcttt gcatggcaag
     1561 tcaggtgaag atggatccat acaaggtctg tttgaattgt ccggtatccc ttttgtaggc
     1621 tgcgatattc aaagctcagc aatttgtatg gacaaatcgt tgacatacat cgttgcgaaa
     1681 aatgctggga tagctactcc cgccttttgg gttattaata aagatgatag gccggtggca
     1741 gctacgttta cctatcctgt ttttgttaag ccggcgcgtt caggctcatc cttcggtgtg
     1801 aaaaaagtca atagcgcgga cgaattggac tacgcaattg aatcggcaag acaatatgac
     1861 agcaaaatct taattgagca ggctgtttcg ggctgtgagg tcggttgtgc ggtattggga
     1921 aacagtgccg cgttagttgt tggcgaggtg gaccaaatca ggctgcagta cggaatcttt
     1981 cgtattcatc aggaagtcga gccggaaaaa ggctctgaaa acgcagttat aaccgttccc
     2041 gcagaccttt cagcagagga gcgaggacgg atacaggaaa cggcaaaaaa aatatataaa
     2101 gcgctcggct gtagaggtct agcccgtgtg gatatgtttt tacaagataa cggccgcatt
     2161 gtactgaacg aagtcaatac tctgcccggt ttcacgtcat acagtcgtta tccccgtatg
     2221 atggccgctg caggtattgc acttcccgaa ctgattgacc gcttgatcgt attagcgtta
     2281 aaggggtgat aagcatggaa ataggattta cttttttaga tgaaatagta cacggtgttc
     2341 gttgggacgc taaatatgcc acttgggata atttcaccgg aaaaccggtt gacggttatg
     2401 aagtaaatcg cattgtaggg acatacgagt tggctgaatc gcttttgaag gcaaaagaac
     2461 tggctgctac ccaagggtac ggattgcttc tatgggacgg ttaccgtcct aagcgtgctg
     2521 taaactgttt tatgcaatgg gctgcacagc cggaaaataa cctgacaaag gaaagttatt
     2581 atcccaatat tgaccgaact gagatgattt caaaaggata cgtggcttca aaatcaagcc
     2641 atagccgcgg cagtgccatt gatcttacgc tttatcgatt agacacgggt gagcttgtac
     2701 caatggggag ccgatttgat tttatggatg aacgctctca tcatgcggca aatggaatat
     2761 catgcaatga agcgcaaaat cgcagacgtt tgcgctccat catggaaaac agtgggtttg
     2821 aagcatatag cctcgaatgg tggcactatg tattaagaga cgaaccatac cccaatagct
     2881 attttgattt ccccgttaaa taaactttta acggttctgt tgcaaagttt taaataaaga
     2941 ataaaatccc
//
LOCUS       DACGLI010000209         1996 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.154, whole genome shotgun sequence.
ACCESSION   DACGLI010000209 DACGLI010000000
VERSION     DACGLI010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.154"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            46..438
                     /locus_tag="IXT22_003140"
     CDS             46..438
                     /locus_tag="IXT22_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4864417.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            439..1878
                     /locus_tag="IXT22_003141"
     CDS             439..1878
                     /locus_tag="IXT22_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HAQ4864418.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          835 a          156 c          335 g          670 t
ORIGIN      
        1 acactaaaat agattttttg gaaaactttg caacagaacc tcctattgaa actattgttt
       61 attgatgata atatggtttt tgatattgat aatttaaaag gatttcttaa tgataccagt
      121 tcatttgggt ttatagctaa agaaaataat aaaattatag gatttgcata ttgctataca
      181 cttttaagac ctgatggaaa aacaatgttt tatttacact caataggaat gttacctaac
      241 tatcaagaca aaggttatgg ttcaaaatta ttatctttta ttaaggaata ttctaaagag
      301 attggttgtt ctgaaatgtt tttaataact gataaaggta atcctagagc ttgccatgta
      361 tatgaaaaat taggtggtaa aaatgattat aaagatgaaa tagtatatgt atatgattat
      421 gaaaaaggtg ataaataaat gaatatagtt gaaaatgaaa tatgtataag aactttaata
      481 gatgatgatt ttcctttgat gttaaaatgg ttaactgatg aaagagtatt agaattttat
      541 gatggtagag ataaaaaata tacattagaa tcattaaaaa aacattatac agagccttgg
      601 gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg atatggacaa
      661 atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac tgatgagata
      721 gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg aattggtaca
      781 agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa tgcagttatt
      841 ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc tggttttaga
      901 attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga ttgttattta
      961 atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata tttaattgag
     1021 cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg ttatgatagt
     1081 gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac taataagaaa
     1141 aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt agaaactaat
     1201 gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat actaggttat
     1261 aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc agaagaagaa
     1321 caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg tttagattat
     1381 acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga gtatatattg
     1441 ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat agaaagtttt
     1501 atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg ccataatgat
     1561 tttagttgta atcatctatt gttagatggc aataatagat taactggaat aattgatttt
     1621 ggagattctg gaattataga tgaatattgt gattttatat acttacttga agatagtgaa
     1681 gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa tatagatatt
     1741 gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga aactattgtt
     1801 tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga aatttataaa
     1861 aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga cattagtatt
     1921 aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga ctcctgtgta
     1981 aaatgctata caatgt
//
LOCUS       DACGLI010000210         1954 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.156, whole genome shotgun sequence.
ACCESSION   DACGLI010000210 DACGLI010000000
VERSION     DACGLI010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.156"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..597
                     /locus_tag="IXT22_003142"
     CDS             <1..597
                     /locus_tag="IXT22_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /protein_id="HAQ4864419.1"
                     /translation="PYLIVDLKLCNRTDNLIRGEFHFLSEKDMNIIPSFKDSGYIPDT
                     KAMLIYDETGQLENYLSEISGARPNRLTEENANFLLCNFSNLWLMGINVLKRGEYARS
                     LELLSQLQKNTLQLIRMAEKNADNWLNMSKNLEKEISLENYKKFAKTTARLDKVELFE
                     AYKNSLLLVMDLQSHLIEQYNLKVTHDILERLLNYISE"
     gene            1285..1954
                     /locus_tag="IXT22_003143"
                     /pseudo
     CDS             1285..1954
                     /locus_tag="IXT22_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          658 a          315 c          402 g          579 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaaccg ataatcttat acgtggggaa
       61 tttcatttcc tttctgaaaa agatatgaac ataatcccct cgtttaaaga ttcaggttat
      121 attcctgata cgaaggctat gcttatttac gatgaaacag ggcaattaga aaattattta
      181 tcagagataa gtggtgcaag accaaataga cttactgaag aaaatgctaa ttttttgttg
      241 tgtaatttct ctaatctatg gttgatggga atcaacgttc taaaaagagg agaatatgct
      301 cgttcattag aactcttatc acaacttcaa aaaaatacac tacaacttat acgtatggca
      361 gaaaaaaatg ctgataattg gctaaacatg agtaaaaacc ttgaaaaaga aattagcctt
      421 gaaaattata aaaaatttgc aaagaccact gctcgattag ataaggtaga attatttgaa
      481 gcctataaaa attctttgct attagttatg gatttgcaaa gtcaccttat tgaacaatac
      541 aacttaaaag ttacacatga cattttagaa agattgttga attacattag tgaataggag
      601 agtaacgtta ttcacagtat tgggtactga aaattaacag catacctcag tttttcaaaa
      661 aacagcgaag cctatggata tgttcccgtc taccgatagt gcaaaaagtg tcgtggatat
      721 gtttccgaga acggacatac acaaatgaca ttcattctgt cctctcaatc catgtggaag
      781 cagtatgtct gttaacaaga aaataattat tgttcgtcct gacgagttgt tagactcgaa
      841 aaggataaac atcattttta gaaccggtag ccgatttttg gctagcggtt ttttgggctc
      901 tttggcaaat agtggtgatt gaatctcgcg ctatcctatg gaaaaccgcc ttgtgtgagg
      961 ggctgcgaga ccgcttcgat cctagaattg ctgaagcacg aatctagcgt cactcacatt
     1021 tcatcttttg acgtagctga gacaaggtgt ttttcttcga tccgctagtg gttaatctct
     1081 ttttggtgca aatatggttt agaatttctt tgcatggctt aagggagtgg agaatcggat
     1141 attagtagga tttacatcca cagataaaaa taggcttgat tttaacagcg aaactaaaat
     1201 accctactta aatgaagtga tagattagat gttgggttgt taggagatgc ttaaaaatcc
     1261 tatgcaatca atagttttta gtgtttgttg acttgatccc taaatcgcct gagtactaaa
     1321 cgttgagtgt gtctgcttac tgtcactagc cagtaagtga gactgtagtt aatctctcat
     1381 tttccccagt attatgttga aaatagccat gaagcgatta tttctaaaga gttatttttg
     1441 caggctcaag aagaaattta tcggagaagt aatatctaca caggagaagg caagaacaaa
     1501 agaatttata gtagcaagta cgctttaagt gccatcacct tctgtggata ttgtggcgat
     1561 atttatagga gaacctattg gaatattcat ggcagaaaag aatttgtctg gcgatgcgtg
     1621 actagaatcg agcagggtcc cgaggtatgt aagaaccgaa ccgtaaaaga agatgaactc
     1681 tatggtgcgg taatgaccgc aattaataag ctacttgctg gtggcaacaa tatgataaag
     1741 acactggaag aaaatattca tgctgtgatt ggagaaacca cagaatacca aatttcagag
     1801 attaataccc tactagatga aaaacaaaaa gaactaatca agctggccaa taaaggtcaa
     1861 gattatgaat acctggtaga tgagatcgat gagatgcgag ataagcgtca gactctttta
     1921 gtagaagatg cctccctcag tggcgagaac gagc
//
LOCUS       DACGLI010000211         1504 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.166, whole genome shotgun sequence.
ACCESSION   DACGLI010000211 DACGLI010000000
VERSION     DACGLI010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.166"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            262..373
                     /locus_tag="IXT22_003144"
                     /pseudo
     CDS             262..373
                     /locus_tag="IXT22_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="IXT22_003145"
     CDS             394..477
                     /locus_tag="IXT22_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HAQ4864420.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="IXT22_003146"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="IXT22_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAQ4864421.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DACGLI010000212         1419 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.170, whole genome shotgun sequence.
ACCESSION   DACGLI010000212 DACGLI010000000
VERSION     DACGLI010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.170"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            <1..1073
                     /locus_tag="IXT22_003147"
     CDS             <1..1073
                     /locus_tag="IXT22_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4864422.1"
                     /translation="DFILYLKLCNRTDARNVVQNYLKRKKGFILVSHDRSLLDQCVDH
                     ILSINKTNIEIQKGNFTSWWENKTLQDNFELAENKKLLKEIGRLSYAAKRSSNWSNKV
                     EKSKYGTTNSGSKLDKGYVGHKAAKAMKRAKNIESRHQEAVLQKSELLHNIEQYDDLK
                     ISPLEFHKECLIEANDLSLSYGDKEVCSNLNFRVNIGDRVAIIGKNGSGKSSILKLIN
                     GDDIKFTGNFMLASGLKISYISQDTSYLKGNLSEFAYNNKIDETLFKTILRKLDFNRE
                     QFDKNMVDFSAGQKKKVLIAKSLCESAHLYIWDEPLNYIDIFSRIQIEKMILEYCPTL
                     LFVEHDDAFCNNICTKNINLGL"
     gene            1127..1384
                     /locus_tag="IXT22_003148"
                     /pseudo
     CDS             1127..1384
                     /locus_tag="IXT22_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
BASE COUNT          525 a          182 c          269 g          443 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccga tgcacgtaat gtagtgcaaa
       61 actatttgaa acgcaagaag gggtttattt tggtatctca tgatagaagc ttacttgatc
      121 aatgtgttga ccatatacta tctatcaata aaacgaatat cgaaatccaa aagggaaatt
      181 ttacttcttg gtgggagaac aaaacgttac aagataattt tgaactggca gaaaacaaga
      241 aactccttaa agaaatagga aggttgtctt atgcagcaaa acgtagttca aactggtcaa
      301 ataaagtaga aaaaagtaaa tatggaacaa caaattctgg ttcaaaactg gataagggtt
      361 atgttggaca taaggctgca aaagcgatga aacgtgccaa aaatattgag tcaagacatc
      421 aggaagccgt tttacaaaaa tcagaactgc tccacaacat tgaacaatat gatgacttaa
      481 aaatttcacc acttgaattt cacaaagagt gcttaataga agcgaatgat ttatcattgt
      541 cttatggaga taaagaagta tgcagtaatc ttaatttcag agtcaatatt ggtgatagag
      601 ttgccattat cggaaaaaat gggagtggta agtctagtat cctaaaattg attaatggag
      661 atgatattaa atttaccgga aattttatgc tagcaagtgg actaaaaatt tcttatattt
      721 cgcaagatac ttcatattta aaaggtaatc tatctgaatt tgcctataat aataagatcg
      781 atgaaactct atttaaaacg attcttcgta aactggattt taatagagag cagtttgata
      841 agaacatggt ggattttagt gctggtcaga aaaagaaagt actaattgct aaaagccttt
      901 gtgaaagtgc acatttgtat atatgggatg agccattgaa ctatattgat attttttcac
      961 gtatccaaat tgaaaaaatg attttggaat attgtcctac actattgttt gtggagcatg
     1021 atgatgcttt ttgcaataac atttgtacga aaaatattaa tttaggtttg tagagatttt
     1081 gagttgccac aataactaaa agatatttac atgaaagggt gaagaaatgt taaaacaaaa
     1141 agaattaatt gcaaacgtta agaatcttac tgagtcagat gaacgaatta cagcttgtat
     1201 gatgtatgga tcgtttacca aaggagaagg tgaccaatac tctgatatag agttctatat
     1261 atttttgaaa gatagtataa cctcgaactt tgattcatcc aactggttgt ttgacgtagc
     1321 tccgtacttg atgctttata aaaatgagta cggaacagag gtagttattt ttgataatct
     1381 ggttctgttg caaagtttta aataaagaat aaaatccct
//
LOCUS       DACGLI010000213         1349 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.176, whole genome shotgun sequence.
ACCESSION   DACGLI010000213 DACGLI010000000
VERSION     DACGLI010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.176"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            46..297
                     /locus_tag="IXT22_003149"
                     /pseudo
     CDS             46..297
                     /locus_tag="IXT22_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            390..1184
                     /locus_tag="IXT22_003150"
                     /note="aph(3')-IIIa"
     CDS             390..1184
                     /locus_tag="IXT22_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAQ4864423.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          424 a          234 c          322 g          369 t
ORIGIN      
        1 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
       61 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      121 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      181 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      241 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      301 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      361 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      421 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      481 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      541 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      601 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      661 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      721 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      781 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      841 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      901 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
      961 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1021 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1081 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1141 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1201 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1261 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1321 cgcctacgag gaatttgtat cgataagaa
//
LOCUS       DACGLI010000214          592 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium strain VREN0499
            SAMEA3304443-rid9560433.guided.204, whole genome shotgun sequence.
ACCESSION   DACGLI010000214 DACGLI010000000
VERSION     DACGLI010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3304443
            Sequence Read Archive: ERR985059
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000702220.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000702220.1
            Genome Coverage       :: 143x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/05/2020 22:55:17
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,151
            CDSs (total)                      :: 3,094
            Genes (coding)                    :: 3,021
            CDSs (with protein)               :: 3,021
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 73
            CDSs (without protein)            :: 73
            Pseudo Genes (ambiguous residues) :: 0 of 73
            Pseudo Genes (frameshifted)       :: 32 of 73
            Pseudo Genes (incomplete)         :: 33 of 73
            Pseudo Genes (internal stop)      :: 22 of 73
            Pseudo Genes (multiple problems)  :: 13 of 73
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3304443-rid9560433.guided.204"
                     /strain="VREN0499"
                     /db_xref="taxon:1352"
     gene            39..488
                     /locus_tag="IXT22_003151"
                     /pseudo
     CDS             39..488
                     /locus_tag="IXT22_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
BASE COUNT          231 a           89 c           76 g          196 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccata taagatatat ggaaatatac
       61 cctacaatat aagtacagat ataattcgaa aaattgtttt tgaaagcaca gctacagaaa
      121 gttatttaat agtggaatat ggatttgcta aaaggttgct aaatacaaat cgttcactag
      181 cactattttt aatgacagaa gttgatatat ccatattaag taaaatccct agagaatact
      241 ttcatccaaa acctagagtt aatagctcgt taattgtatt aaaaagacac ccttcaaaaa
      301 tatcactcaa agatagaaaa caatatgaaa attttgttat gaaatgggtt aacaaagaat
      361 acataaaact attttccaaa aaccaatttt atcaagcctt aaaatatgca agaattgacg
      421 atttaaacaa tattagcttt gaacaattct tgtctctttt caatagctat aaattattta
      481 atagataagt taaggggtgc ataaactgca tcccttaact tatcttattt tgcttaaaca
      541 atcttggccc gtaaactgca taactcatat gtaaatcgct cctttttagg tg
//
